ORF_ID e_value Gene_name EC_number CAZy COGs Description
DHMILLCL_00001 6.7e-248 S zinc finger
DHMILLCL_00002 7.5e-71 S Bacterial PH domain
DHMILLCL_00003 1.5e-76
DHMILLCL_00004 1.8e-49 V Domain of unknown function (DUF3427)
DHMILLCL_00005 1.7e-87 3.1.21.7 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
DHMILLCL_00006 1.2e-88 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DHMILLCL_00007 2.1e-90
DHMILLCL_00008 4e-53 K TfoX N-terminal domain
DHMILLCL_00009 5.4e-141 V Domain of unknown function (DUF3427)
DHMILLCL_00010 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
DHMILLCL_00011 7.2e-189 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DHMILLCL_00012 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DHMILLCL_00013 1.1e-233 aspB E Aminotransferase class-V
DHMILLCL_00014 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DHMILLCL_00015 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
DHMILLCL_00016 3.4e-22 M cell wall anchor domain protein
DHMILLCL_00017 6.2e-199 S Endonuclease/Exonuclease/phosphatase family
DHMILLCL_00019 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHMILLCL_00020 1.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DHMILLCL_00021 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DHMILLCL_00022 1.1e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DHMILLCL_00023 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
DHMILLCL_00024 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DHMILLCL_00025 5.5e-255 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DHMILLCL_00026 9.4e-115 K Bacterial regulatory proteins, tetR family
DHMILLCL_00027 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
DHMILLCL_00028 1.7e-111 K Bacterial regulatory proteins, tetR family
DHMILLCL_00029 1.9e-218 G Transporter major facilitator family protein
DHMILLCL_00031 1.2e-271 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
DHMILLCL_00033 4.4e-08 Q Non-ribosomal peptide synthetase modules and related proteins
DHMILLCL_00034 1.9e-209 hsvB 6.3.2.4 M Belongs to the D-alanine--D-alanine ligase family
DHMILLCL_00035 2e-130 ydjE EGP Major facilitator Superfamily
DHMILLCL_00036 3.1e-19 Q Belongs to the P-Pant transferase superfamily
DHMILLCL_00037 2.8e-69 dap2 E peptidase
DHMILLCL_00038 9.3e-199 P Major Facilitator Superfamily
DHMILLCL_00039 8.9e-247 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DHMILLCL_00040 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
DHMILLCL_00041 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DHMILLCL_00042 2.3e-108 K Bacterial regulatory proteins, tetR family
DHMILLCL_00043 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
DHMILLCL_00044 1.9e-212 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DHMILLCL_00045 5.1e-107 K Bacterial regulatory proteins, tetR family
DHMILLCL_00046 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DHMILLCL_00047 1.3e-96 K MarR family
DHMILLCL_00048 0.0 V ABC transporter, ATP-binding protein
DHMILLCL_00049 0.0 V ABC transporter transmembrane region
DHMILLCL_00050 9e-184 lacR K Transcriptional regulator, LacI family
DHMILLCL_00051 3.9e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
DHMILLCL_00052 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DHMILLCL_00053 0.0 cas3 L DEAD-like helicases superfamily
DHMILLCL_00054 1.2e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
DHMILLCL_00055 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
DHMILLCL_00056 4.5e-152 csd2 L CRISPR-associated protein Cas7
DHMILLCL_00057 1.7e-130 cas4 3.1.12.1 L Domain of unknown function DUF83
DHMILLCL_00058 7.2e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHMILLCL_00059 1.9e-46 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DHMILLCL_00060 1.6e-120 S Phospholipase/Carboxylesterase
DHMILLCL_00061 2.4e-239 patB 4.4.1.8 E Aminotransferase, class I II
DHMILLCL_00062 1.9e-186 K LysR substrate binding domain protein
DHMILLCL_00063 2.9e-159 S Patatin-like phospholipase
DHMILLCL_00064 3.8e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
DHMILLCL_00065 8.6e-301 E ABC transporter, substrate-binding protein, family 5
DHMILLCL_00066 3.5e-21 S Patatin-like phospholipase
DHMILLCL_00067 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DHMILLCL_00068 8.6e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DHMILLCL_00069 2.1e-117 S Vitamin K epoxide reductase
DHMILLCL_00070 1.1e-172 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DHMILLCL_00071 3.6e-32 S Protein of unknown function (DUF3107)
DHMILLCL_00072 4.7e-269 mphA S Aminoglycoside phosphotransferase
DHMILLCL_00073 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
DHMILLCL_00074 1.6e-283 S Zincin-like metallopeptidase
DHMILLCL_00075 1e-154 lon T Belongs to the peptidase S16 family
DHMILLCL_00076 6.5e-75 S Protein of unknown function (DUF3052)
DHMILLCL_00078 4.4e-238 2.7.11.1 NU Tfp pilus assembly protein FimV
DHMILLCL_00079 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DHMILLCL_00080 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DHMILLCL_00081 0.0 I acetylesterase activity
DHMILLCL_00082 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
DHMILLCL_00083 4.5e-154 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DHMILLCL_00084 3.2e-218 iunH1 3.2.2.1 F nucleoside hydrolase
DHMILLCL_00085 5.3e-206 P NMT1/THI5 like
DHMILLCL_00086 1.8e-140 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_00087 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DHMILLCL_00088 4.7e-241 lacY P LacY proton/sugar symporter
DHMILLCL_00089 1.1e-192 K helix_turn _helix lactose operon repressor
DHMILLCL_00090 3e-60 S Thiamine-binding protein
DHMILLCL_00091 1.2e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DHMILLCL_00092 5.4e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DHMILLCL_00093 9.9e-155 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DHMILLCL_00094 0.0
DHMILLCL_00095 0.0 pilT NU Type II/IV secretion system protein
DHMILLCL_00096 0.0 pulE NU Type II/IV secretion system protein
DHMILLCL_00097 2.4e-136 ppdC NU Prokaryotic N-terminal methylation motif
DHMILLCL_00098 2.1e-104 S Prokaryotic N-terminal methylation motif
DHMILLCL_00099 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
DHMILLCL_00100 4.7e-230 pilC U Type II secretion system (T2SS), protein F
DHMILLCL_00101 0.0
DHMILLCL_00102 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DHMILLCL_00103 2.5e-189 pilM NU Type IV pilus assembly protein PilM;
DHMILLCL_00104 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
DHMILLCL_00105 1e-105 S Pilus assembly protein, PilO
DHMILLCL_00106 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DHMILLCL_00107 2.2e-245 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DHMILLCL_00108 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DHMILLCL_00109 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DHMILLCL_00110 6.9e-41 yggT S YGGT family
DHMILLCL_00111 1.3e-30 3.1.21.3 V DivIVA protein
DHMILLCL_00112 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DHMILLCL_00113 4.2e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DHMILLCL_00114 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DHMILLCL_00115 1.3e-257 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DHMILLCL_00116 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DHMILLCL_00117 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DHMILLCL_00118 1.5e-122
DHMILLCL_00119 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DHMILLCL_00120 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DHMILLCL_00121 1.2e-263 glnA2 6.3.1.2 E glutamine synthetase
DHMILLCL_00122 3.7e-218 S Domain of unknown function (DUF5067)
DHMILLCL_00123 3.6e-139 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DHMILLCL_00124 1.5e-220 EGP Major facilitator Superfamily
DHMILLCL_00125 1.9e-118 ytrE V ATPases associated with a variety of cellular activities
DHMILLCL_00126 1.5e-28 2.7.13.3 T Histidine kinase
DHMILLCL_00127 5.4e-57 T helix_turn_helix, Lux Regulon
DHMILLCL_00128 4.5e-83
DHMILLCL_00129 1.2e-155 V N-Acetylmuramoyl-L-alanine amidase
DHMILLCL_00130 2.4e-187
DHMILLCL_00131 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DHMILLCL_00132 5.9e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DHMILLCL_00133 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DHMILLCL_00134 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DHMILLCL_00135 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DHMILLCL_00136 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DHMILLCL_00137 2.3e-53 M Lysin motif
DHMILLCL_00138 8.5e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DHMILLCL_00139 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DHMILLCL_00140 0.0 L DNA helicase
DHMILLCL_00141 7e-92 mraZ K Belongs to the MraZ family
DHMILLCL_00142 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DHMILLCL_00143 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DHMILLCL_00144 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DHMILLCL_00145 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHMILLCL_00146 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DHMILLCL_00147 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DHMILLCL_00148 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DHMILLCL_00149 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DHMILLCL_00150 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DHMILLCL_00151 5.2e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
DHMILLCL_00152 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
DHMILLCL_00153 2.4e-247 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
DHMILLCL_00154 1.6e-27
DHMILLCL_00155 1.3e-219 S Metal-independent alpha-mannosidase (GH125)
DHMILLCL_00156 2.9e-165 2.7.1.4 G pfkB family carbohydrate kinase
DHMILLCL_00157 1.7e-218 GK ROK family
DHMILLCL_00158 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
DHMILLCL_00159 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_00160 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_00161 0.0 P Belongs to the ABC transporter superfamily
DHMILLCL_00162 9e-95 3.6.1.55 F NUDIX domain
DHMILLCL_00163 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DHMILLCL_00164 2.5e-289 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DHMILLCL_00165 1.5e-186 V Acetyltransferase (GNAT) domain
DHMILLCL_00166 1e-279 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DHMILLCL_00167 2.5e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DHMILLCL_00168 1.2e-36
DHMILLCL_00169 2.8e-187 galM 5.1.3.3 G Aldose 1-epimerase
DHMILLCL_00170 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DHMILLCL_00171 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DHMILLCL_00172 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DHMILLCL_00173 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DHMILLCL_00174 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DHMILLCL_00175 2.1e-25 rpmI J Ribosomal protein L35
DHMILLCL_00176 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DHMILLCL_00177 7.7e-177 xerD D recombinase XerD
DHMILLCL_00178 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DHMILLCL_00179 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
DHMILLCL_00180 1.7e-249 naiP U Sugar (and other) transporter
DHMILLCL_00181 0.0 typA T Elongation factor G C-terminus
DHMILLCL_00182 4e-104
DHMILLCL_00183 3.7e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DHMILLCL_00184 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DHMILLCL_00185 2.8e-34
DHMILLCL_00186 5.2e-08
DHMILLCL_00187 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DHMILLCL_00188 0.0 E ABC transporter, substrate-binding protein, family 5
DHMILLCL_00189 0.0 E ABC transporter, substrate-binding protein, family 5
DHMILLCL_00190 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_00191 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
DHMILLCL_00192 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
DHMILLCL_00193 3e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DHMILLCL_00194 3.7e-151 S Protein of unknown function (DUF3710)
DHMILLCL_00195 2.4e-133 S Protein of unknown function (DUF3159)
DHMILLCL_00196 1.1e-242 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DHMILLCL_00197 1.5e-98
DHMILLCL_00198 0.0 ctpE P E1-E2 ATPase
DHMILLCL_00199 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DHMILLCL_00200 3.7e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_00201 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DHMILLCL_00202 5e-209 rhaR1 K helix_turn_helix, arabinose operon control protein
DHMILLCL_00203 8.9e-229 V ABC-2 family transporter protein
DHMILLCL_00204 2.2e-224 V ABC-2 family transporter protein
DHMILLCL_00205 4.4e-191 V ATPases associated with a variety of cellular activities
DHMILLCL_00206 2.1e-244 T Histidine kinase
DHMILLCL_00207 9e-116 K helix_turn_helix, Lux Regulon
DHMILLCL_00208 0.0 S Protein of unknown function DUF262
DHMILLCL_00209 1.8e-127 K helix_turn_helix, Lux Regulon
DHMILLCL_00210 5.1e-243 T Histidine kinase
DHMILLCL_00211 6.7e-60 S Domain of unknown function (DUF5067)
DHMILLCL_00212 4.9e-127 ybhL S Belongs to the BI1 family
DHMILLCL_00213 8e-177 ydeD EG EamA-like transporter family
DHMILLCL_00214 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DHMILLCL_00215 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DHMILLCL_00216 1.9e-192 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DHMILLCL_00217 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DHMILLCL_00218 0.0 ftsK D FtsK SpoIIIE family protein
DHMILLCL_00219 1.6e-123 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHMILLCL_00220 5.5e-98 cinA 3.5.1.42 S Belongs to the CinA family
DHMILLCL_00221 6.1e-80 K Helix-turn-helix XRE-family like proteins
DHMILLCL_00222 4.3e-46 S Protein of unknown function (DUF3046)
DHMILLCL_00223 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DHMILLCL_00224 1.7e-122 recX S Modulates RecA activity
DHMILLCL_00225 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DHMILLCL_00226 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DHMILLCL_00227 1.9e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DHMILLCL_00228 6.5e-97
DHMILLCL_00229 9.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
DHMILLCL_00230 0.0 pknL 2.7.11.1 KLT PASTA
DHMILLCL_00231 1e-196 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DHMILLCL_00232 1.1e-118
DHMILLCL_00233 3.4e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DHMILLCL_00234 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DHMILLCL_00235 1.5e-222 G Major Facilitator Superfamily
DHMILLCL_00236 2.5e-242 T PhoQ Sensor
DHMILLCL_00237 4.6e-78 S Protein of unknown function (DUF2975)
DHMILLCL_00238 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
DHMILLCL_00239 0.0 lhr L DEAD DEAH box helicase
DHMILLCL_00240 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DHMILLCL_00241 5.2e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
DHMILLCL_00242 7e-147 S Protein of unknown function (DUF3071)
DHMILLCL_00243 1e-47 S Domain of unknown function (DUF4193)
DHMILLCL_00244 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DHMILLCL_00245 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DHMILLCL_00246 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DHMILLCL_00247 2.5e-245 dinF V MatE
DHMILLCL_00248 0.0 S LPXTG-motif cell wall anchor domain protein
DHMILLCL_00249 1.4e-110 S Sucrose-6F-phosphate phosphohydrolase
DHMILLCL_00251 1.9e-149 metQ P NLPA lipoprotein
DHMILLCL_00252 8.7e-175 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHMILLCL_00253 1.3e-93 metI P Binding-protein-dependent transport system inner membrane component
DHMILLCL_00254 1.2e-211 S Peptidase dimerisation domain
DHMILLCL_00255 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DHMILLCL_00256 4.5e-31
DHMILLCL_00257 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DHMILLCL_00258 2.8e-165 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DHMILLCL_00259 9.9e-80 S Protein of unknown function (DUF3000)
DHMILLCL_00260 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
DHMILLCL_00261 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DHMILLCL_00262 5e-131 yebE S DUF218 domain
DHMILLCL_00263 7.1e-127 E Psort location Cytoplasmic, score 8.87
DHMILLCL_00264 1.5e-158 O Thioredoxin
DHMILLCL_00265 4.7e-12 msbA2 3.6.3.44 V ABC transporter transmembrane region
DHMILLCL_00266 1.4e-93 msbA2 3.6.3.44 V ABC transporter transmembrane region
DHMILLCL_00267 4.2e-138 3.6.3.44 V ABC transporter
DHMILLCL_00268 0.0 KLT Lanthionine synthetase C-like protein
DHMILLCL_00269 1.6e-112 K helix_turn_helix, Lux Regulon
DHMILLCL_00270 4.8e-136 2.7.13.3 T Histidine kinase
DHMILLCL_00273 1.3e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DHMILLCL_00274 2.9e-156 S phosphoesterase or phosphohydrolase
DHMILLCL_00275 2.3e-212
DHMILLCL_00276 8.6e-70
DHMILLCL_00277 3.2e-22
DHMILLCL_00278 2.2e-65 S Putative inner membrane protein (DUF1819)
DHMILLCL_00279 1.6e-41 lexA 3.6.4.12 K Putative DNA-binding domain
DHMILLCL_00280 2.6e-131 XK26_04895
DHMILLCL_00281 0.0 KL Type III restriction enzyme res subunit
DHMILLCL_00282 4.7e-108 L Eco57I restriction-modification methylase
DHMILLCL_00283 1.8e-56 L Eco57I restriction-modification methylase
DHMILLCL_00284 3.9e-184 3.1.21.4 V Type III restriction enzyme res subunit
DHMILLCL_00285 4.2e-56 S SIR2-like domain
DHMILLCL_00286 8.5e-252 S AAA-like domain
DHMILLCL_00287 0.0 S Protein of unknown function DUF262
DHMILLCL_00288 4.9e-33 S Protein of unknown function DUF262
DHMILLCL_00290 1.2e-123 3.2.1.8 S alpha beta
DHMILLCL_00291 1.7e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DHMILLCL_00292 1.3e-182 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DHMILLCL_00293 1.3e-113 kcsA U Ion channel
DHMILLCL_00294 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DHMILLCL_00295 6.1e-109 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DHMILLCL_00296 0.0 ecfA GP ABC transporter, ATP-binding protein
DHMILLCL_00297 2.4e-47 yhbY J CRS1_YhbY
DHMILLCL_00298 4.1e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DHMILLCL_00299 3.7e-201 S Glycosyltransferase, group 2 family protein
DHMILLCL_00300 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DHMILLCL_00301 8.1e-221 E Aminotransferase class I and II
DHMILLCL_00302 5e-145 bioM P ATPases associated with a variety of cellular activities
DHMILLCL_00303 1.6e-307 2.8.2.22 S Arylsulfotransferase Ig-like domain
DHMILLCL_00304 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DHMILLCL_00305 0.0 S Tetratricopeptide repeat
DHMILLCL_00306 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DHMILLCL_00307 5.3e-212 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DHMILLCL_00308 1.9e-83 ykoE S ABC-type cobalt transport system, permease component
DHMILLCL_00309 9e-265 ykoD P ATPases associated with a variety of cellular activities
DHMILLCL_00310 3.1e-145 cbiQ P Cobalt transport protein
DHMILLCL_00311 2.5e-253 argE E Peptidase dimerisation domain
DHMILLCL_00312 4.4e-93 S Protein of unknown function (DUF3043)
DHMILLCL_00313 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DHMILLCL_00314 6e-143 S Domain of unknown function (DUF4191)
DHMILLCL_00315 7.8e-282 glnA 6.3.1.2 E glutamine synthetase
DHMILLCL_00316 4e-42 V DNA modification
DHMILLCL_00317 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
DHMILLCL_00318 1.5e-17 L HNH endonuclease
DHMILLCL_00320 4.5e-18
DHMILLCL_00321 1.3e-96 yvdD 3.2.2.10 S Possible lysine decarboxylase
DHMILLCL_00322 1.5e-11 V FtsX-like permease family
DHMILLCL_00324 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DHMILLCL_00325 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DHMILLCL_00326 4.9e-99
DHMILLCL_00327 4.1e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DHMILLCL_00328 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DHMILLCL_00329 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DHMILLCL_00330 1e-240 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DHMILLCL_00331 7.1e-186 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DHMILLCL_00332 3.5e-83 argR K Regulates arginine biosynthesis genes
DHMILLCL_00333 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DHMILLCL_00334 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
DHMILLCL_00335 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DHMILLCL_00336 8.6e-137 S Putative ABC-transporter type IV
DHMILLCL_00337 0.0 S Protein of unknown function (DUF975)
DHMILLCL_00338 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DHMILLCL_00339 1.5e-149 L Tetratricopeptide repeat
DHMILLCL_00340 2e-191 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DHMILLCL_00341 1.2e-130 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DHMILLCL_00342 1.3e-114 trkA P TrkA-N domain
DHMILLCL_00343 1.5e-259 trkB P Cation transport protein
DHMILLCL_00344 2.2e-176 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DHMILLCL_00345 1.4e-261 recN L May be involved in recombinational repair of damaged DNA
DHMILLCL_00346 4.4e-123 S Haloacid dehalogenase-like hydrolase
DHMILLCL_00347 3.3e-116 S ABC-2 family transporter protein
DHMILLCL_00348 9.2e-175 V ATPases associated with a variety of cellular activities
DHMILLCL_00349 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
DHMILLCL_00350 4.3e-23 C Acetamidase/Formamidase family
DHMILLCL_00351 2.7e-44 L transposition
DHMILLCL_00352 0.0 S Histidine phosphatase superfamily (branch 2)
DHMILLCL_00353 1.1e-95 S Pyridoxamine 5'-phosphate oxidase
DHMILLCL_00354 3.3e-22 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00355 8.1e-91 bcp 1.11.1.15 O Redoxin
DHMILLCL_00357 2.5e-56 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DHMILLCL_00358 1.2e-166 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DHMILLCL_00359 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
DHMILLCL_00360 2e-142
DHMILLCL_00361 7.4e-174 G Fic/DOC family
DHMILLCL_00362 4.5e-73 3.1.3.27 E haloacid dehalogenase-like hydrolase
DHMILLCL_00363 1e-232 EGP Major facilitator Superfamily
DHMILLCL_00364 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
DHMILLCL_00365 1.9e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DHMILLCL_00366 1.5e-242 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DHMILLCL_00367 3.2e-101
DHMILLCL_00368 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DHMILLCL_00369 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHMILLCL_00371 5.4e-121
DHMILLCL_00372 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DHMILLCL_00373 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHMILLCL_00374 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
DHMILLCL_00375 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DHMILLCL_00377 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DHMILLCL_00378 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DHMILLCL_00379 8e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DHMILLCL_00380 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DHMILLCL_00381 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DHMILLCL_00382 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DHMILLCL_00383 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DHMILLCL_00384 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DHMILLCL_00385 1.1e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DHMILLCL_00386 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DHMILLCL_00387 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DHMILLCL_00388 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DHMILLCL_00389 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DHMILLCL_00390 1.8e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DHMILLCL_00391 2.9e-171 S Bacterial protein of unknown function (DUF881)
DHMILLCL_00392 4.2e-45 sbp S Protein of unknown function (DUF1290)
DHMILLCL_00393 1.6e-141 S Bacterial protein of unknown function (DUF881)
DHMILLCL_00394 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DHMILLCL_00395 8.7e-111 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
DHMILLCL_00396 5.2e-128 yebC K transcriptional regulatory protein
DHMILLCL_00397 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DHMILLCL_00398 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DHMILLCL_00399 3.1e-198 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DHMILLCL_00400 9.4e-60 yajC U Preprotein translocase subunit
DHMILLCL_00401 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DHMILLCL_00402 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DHMILLCL_00403 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DHMILLCL_00404 8.7e-246
DHMILLCL_00405 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DHMILLCL_00406 8.2e-34
DHMILLCL_00407 1.5e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DHMILLCL_00408 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DHMILLCL_00409 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DHMILLCL_00410 1.1e-69
DHMILLCL_00412 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DHMILLCL_00413 0.0 pafB K WYL domain
DHMILLCL_00414 2.1e-54
DHMILLCL_00415 0.0 helY L DEAD DEAH box helicase
DHMILLCL_00416 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DHMILLCL_00417 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
DHMILLCL_00418 4.6e-61
DHMILLCL_00419 9.7e-112 K helix_turn_helix, mercury resistance
DHMILLCL_00420 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
DHMILLCL_00421 5.4e-36
DHMILLCL_00422 2.5e-08
DHMILLCL_00429 1.6e-156 S PAC2 family
DHMILLCL_00430 5.4e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DHMILLCL_00431 2.5e-157 G Fructosamine kinase
DHMILLCL_00432 8.9e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DHMILLCL_00433 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DHMILLCL_00434 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DHMILLCL_00435 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DHMILLCL_00436 2.6e-42 nadR H ATPase kinase involved in NAD metabolism
DHMILLCL_00437 2.2e-36 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
DHMILLCL_00438 3.5e-67 pnuC H Nicotinamide mononucleotide transporter
DHMILLCL_00439 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
DHMILLCL_00440 2.3e-300 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DHMILLCL_00441 1.3e-162 S Sucrose-6F-phosphate phosphohydrolase
DHMILLCL_00442 2.4e-32 secG U Preprotein translocase SecG subunit
DHMILLCL_00443 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DHMILLCL_00444 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DHMILLCL_00445 1.3e-171 whiA K May be required for sporulation
DHMILLCL_00446 1.1e-170 rapZ S Displays ATPase and GTPase activities
DHMILLCL_00447 7.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DHMILLCL_00448 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DHMILLCL_00449 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DHMILLCL_00450 2.9e-133 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00451 1.5e-22 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00452 0.0 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00453 4.7e-140 S Domain of unknown function (DUF4194)
DHMILLCL_00454 6.9e-274 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00455 2e-13
DHMILLCL_00457 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DHMILLCL_00458 2.3e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DHMILLCL_00459 1.3e-298 ybiT S ABC transporter
DHMILLCL_00460 1e-173 S IMP dehydrogenase activity
DHMILLCL_00461 6.7e-278 pepC 3.4.22.40 E Peptidase C1-like family
DHMILLCL_00462 1.7e-145 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00463 3.4e-145
DHMILLCL_00464 6.3e-104
DHMILLCL_00467 2.5e-181 cat P Cation efflux family
DHMILLCL_00468 5.3e-75 S Psort location CytoplasmicMembrane, score
DHMILLCL_00469 5.5e-222 yxjG_1 E Psort location Cytoplasmic, score 8.87
DHMILLCL_00470 1.9e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
DHMILLCL_00471 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DHMILLCL_00472 6.7e-72 K MerR family regulatory protein
DHMILLCL_00473 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
DHMILLCL_00474 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DHMILLCL_00475 4.6e-119 yoaP E YoaP-like
DHMILLCL_00477 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DHMILLCL_00478 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DHMILLCL_00479 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
DHMILLCL_00480 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DHMILLCL_00481 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
DHMILLCL_00482 0.0 comE S Competence protein
DHMILLCL_00483 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DHMILLCL_00484 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DHMILLCL_00485 2.5e-142 ET Bacterial periplasmic substrate-binding proteins
DHMILLCL_00486 5.7e-172 corA P CorA-like Mg2+ transporter protein
DHMILLCL_00487 2.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DHMILLCL_00488 5.2e-65 3.4.22.70 M Sortase family
DHMILLCL_00489 8.1e-82 3.4.22.70 M Sortase family
DHMILLCL_00490 1.2e-302 M domain protein
DHMILLCL_00491 9.2e-71 pdxH S Pfam:Pyridox_oxidase
DHMILLCL_00492 2.9e-232 XK27_00240 K Fic/DOC family
DHMILLCL_00494 3.3e-118
DHMILLCL_00495 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DHMILLCL_00496 5.6e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DHMILLCL_00497 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DHMILLCL_00498 1.8e-72 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DHMILLCL_00499 6.1e-108 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DHMILLCL_00500 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
DHMILLCL_00501 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DHMILLCL_00502 1.1e-268 G ABC transporter substrate-binding protein
DHMILLCL_00503 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
DHMILLCL_00504 3.3e-96 M Peptidase family M23
DHMILLCL_00505 1.6e-61
DHMILLCL_00508 5e-125 XK27_06785 V ABC transporter
DHMILLCL_00509 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DHMILLCL_00510 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DHMILLCL_00511 5.1e-139 S SdpI/YhfL protein family
DHMILLCL_00512 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
DHMILLCL_00513 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DHMILLCL_00514 2e-32 yxjG_1 E Psort location Cytoplasmic, score 8.87
DHMILLCL_00515 3.1e-172 yxjG_1 E Psort location Cytoplasmic, score 8.87
DHMILLCL_00516 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DHMILLCL_00517 9.7e-108 J Acetyltransferase (GNAT) domain
DHMILLCL_00518 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DHMILLCL_00519 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DHMILLCL_00520 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DHMILLCL_00521 4.7e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DHMILLCL_00522 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DHMILLCL_00523 3.5e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DHMILLCL_00524 1.5e-277 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DHMILLCL_00525 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DHMILLCL_00526 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DHMILLCL_00527 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DHMILLCL_00528 4.3e-155 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DHMILLCL_00529 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DHMILLCL_00530 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
DHMILLCL_00531 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DHMILLCL_00532 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DHMILLCL_00533 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DHMILLCL_00534 2e-74
DHMILLCL_00535 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DHMILLCL_00536 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DHMILLCL_00537 1.9e-234 F Psort location CytoplasmicMembrane, score 10.00
DHMILLCL_00538 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
DHMILLCL_00539 7.6e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
DHMILLCL_00540 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DHMILLCL_00541 4.3e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
DHMILLCL_00542 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DHMILLCL_00543 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
DHMILLCL_00544 1.1e-133 S UPF0126 domain
DHMILLCL_00545 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
DHMILLCL_00547 2.3e-58 K Acetyltransferase (GNAT) domain
DHMILLCL_00548 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHMILLCL_00549 9.1e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHMILLCL_00550 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DHMILLCL_00551 3.8e-195 S alpha beta
DHMILLCL_00552 1.3e-25 yhjX EGP Major facilitator Superfamily
DHMILLCL_00553 2.6e-30 EGP Major facilitator Superfamily
DHMILLCL_00554 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DHMILLCL_00555 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHMILLCL_00557 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DHMILLCL_00558 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
DHMILLCL_00559 1.1e-39 nrdH O Glutaredoxin
DHMILLCL_00561 7e-121 K Bacterial regulatory proteins, tetR family
DHMILLCL_00562 4.6e-225 G Transmembrane secretion effector
DHMILLCL_00564 1.9e-269 S Psort location Cytoplasmic, score 8.87
DHMILLCL_00565 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DHMILLCL_00566 1.8e-42 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DHMILLCL_00567 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DHMILLCL_00568 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DHMILLCL_00569 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DHMILLCL_00570 4.1e-251 corC S CBS domain
DHMILLCL_00571 3.6e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DHMILLCL_00572 1.3e-207 phoH T PhoH-like protein
DHMILLCL_00573 4.1e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DHMILLCL_00574 8.5e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DHMILLCL_00576 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
DHMILLCL_00577 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DHMILLCL_00578 2.7e-108 yitW S Iron-sulfur cluster assembly protein
DHMILLCL_00579 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
DHMILLCL_00580 1.9e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DHMILLCL_00581 1e-142 sufC O FeS assembly ATPase SufC
DHMILLCL_00582 6.1e-235 sufD O FeS assembly protein SufD
DHMILLCL_00583 1.6e-290 sufB O FeS assembly protein SufB
DHMILLCL_00584 0.0 S L,D-transpeptidase catalytic domain
DHMILLCL_00585 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DHMILLCL_00586 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
DHMILLCL_00587 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DHMILLCL_00588 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DHMILLCL_00589 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DHMILLCL_00590 9.3e-57 3.4.23.43 S Type IV leader peptidase family
DHMILLCL_00591 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DHMILLCL_00592 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DHMILLCL_00593 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DHMILLCL_00594 3.6e-35
DHMILLCL_00595 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DHMILLCL_00596 5.6e-129 pgm3 G Phosphoglycerate mutase family
DHMILLCL_00597 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DHMILLCL_00598 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DHMILLCL_00599 4.6e-149 lolD V ABC transporter
DHMILLCL_00600 2e-214 V FtsX-like permease family
DHMILLCL_00601 1.7e-61 S Domain of unknown function (DUF4418)
DHMILLCL_00602 0.0 pcrA 3.6.4.12 L DNA helicase
DHMILLCL_00603 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DHMILLCL_00604 2.8e-244 pbuX F Permease family
DHMILLCL_00605 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_00606 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DHMILLCL_00607 5.1e-301 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DHMILLCL_00608 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DHMILLCL_00609 7.4e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DHMILLCL_00610 4e-42
DHMILLCL_00611 4e-15 K Helix-turn-helix XRE-family like proteins
DHMILLCL_00612 1.8e-93 S Domain of unknown function (DUF4263)
DHMILLCL_00613 2.3e-98
DHMILLCL_00614 4.3e-94
DHMILLCL_00615 3.6e-68 M Cna protein B-type domain
DHMILLCL_00616 5.6e-250 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DHMILLCL_00618 5.1e-207 ykiI
DHMILLCL_00619 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DHMILLCL_00620 6.4e-122 3.6.1.13 L NUDIX domain
DHMILLCL_00621 1.1e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DHMILLCL_00622 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DHMILLCL_00623 9.4e-101 pdtaR T Response regulator receiver domain protein
DHMILLCL_00624 2.9e-162 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DHMILLCL_00625 4.9e-76 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
DHMILLCL_00626 5e-107 L Belongs to the 'phage' integrase family
DHMILLCL_00627 1.8e-53 3.1.21.3 V Type I restriction modification DNA specificity domain protein
DHMILLCL_00628 7.8e-38 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
DHMILLCL_00629 5.2e-244 hsdM 2.1.1.72 V HsdM N-terminal domain
DHMILLCL_00630 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
DHMILLCL_00631 5.1e-37 pcrA1 3.6.4.12 F DNA helicase
DHMILLCL_00632 1.6e-101 E Binding-protein-dependent transport system inner membrane component
DHMILLCL_00633 1.4e-121 tcyA ET Bacterial periplasmic substrate-binding proteins
DHMILLCL_00634 3.2e-115 3.6.3.21 E ATPases associated with a variety of cellular activities
DHMILLCL_00635 2.1e-195 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DHMILLCL_00637 2.9e-18 relB L RelB antitoxin
DHMILLCL_00639 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
DHMILLCL_00640 5.7e-175 terC P Integral membrane protein, TerC family
DHMILLCL_00641 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DHMILLCL_00642 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DHMILLCL_00643 8.3e-255 rpsA J Ribosomal protein S1
DHMILLCL_00644 7.1e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DHMILLCL_00645 4.2e-171 P Zinc-uptake complex component A periplasmic
DHMILLCL_00646 2e-160 znuC P ATPases associated with a variety of cellular activities
DHMILLCL_00647 3.9e-140 znuB U ABC 3 transport family
DHMILLCL_00648 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DHMILLCL_00649 3e-102 carD K CarD-like/TRCF domain
DHMILLCL_00650 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DHMILLCL_00651 2e-129 T Response regulator receiver domain protein
DHMILLCL_00652 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DHMILLCL_00653 5.5e-138 ctsW S Phosphoribosyl transferase domain
DHMILLCL_00654 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DHMILLCL_00655 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DHMILLCL_00656 8.7e-223
DHMILLCL_00657 0.0 S Glycosyl transferase, family 2
DHMILLCL_00658 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DHMILLCL_00659 5.7e-208 K Cell envelope-related transcriptional attenuator domain
DHMILLCL_00661 2.6e-169 K Cell envelope-related transcriptional attenuator domain
DHMILLCL_00662 0.0 D FtsK/SpoIIIE family
DHMILLCL_00663 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DHMILLCL_00664 3.9e-276 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DHMILLCL_00665 2.7e-144 yplQ S Haemolysin-III related
DHMILLCL_00666 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DHMILLCL_00667 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DHMILLCL_00668 6.5e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DHMILLCL_00669 1.8e-91
DHMILLCL_00671 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DHMILLCL_00672 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DHMILLCL_00673 2e-71 divIC D Septum formation initiator
DHMILLCL_00674 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DHMILLCL_00675 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DHMILLCL_00676 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DHMILLCL_00677 4.7e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
DHMILLCL_00678 0.0 S Uncharacterised protein family (UPF0182)
DHMILLCL_00679 3.1e-178 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DHMILLCL_00680 6.2e-40 ybdD S Selenoprotein, putative
DHMILLCL_00681 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
DHMILLCL_00682 1.2e-52 azlD E Branched-chain amino acid transport protein (AzlD)
DHMILLCL_00683 6.1e-143 azlC E AzlC protein
DHMILLCL_00684 6e-88 M Protein of unknown function (DUF3737)
DHMILLCL_00685 7.1e-83 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DHMILLCL_00686 1.9e-144 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DHMILLCL_00687 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
DHMILLCL_00688 3.6e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DHMILLCL_00689 3.1e-236 patB 4.4.1.8 E Aminotransferase, class I II
DHMILLCL_00690 1e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DHMILLCL_00691 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DHMILLCL_00692 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DHMILLCL_00693 7.7e-242 S Putative esterase
DHMILLCL_00694 3.2e-142 ybbL V ATPases associated with a variety of cellular activities
DHMILLCL_00695 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
DHMILLCL_00696 6.8e-271 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DHMILLCL_00697 6e-126 S Enoyl-(Acyl carrier protein) reductase
DHMILLCL_00698 2.9e-227 rutG F Permease family
DHMILLCL_00699 5.4e-155 3.1.3.73 G Phosphoglycerate mutase family
DHMILLCL_00700 7e-141 K helix_turn_helix, arabinose operon control protein
DHMILLCL_00701 1.4e-137 S Sulfite exporter TauE/SafE
DHMILLCL_00702 1.9e-93 S ECF transporter, substrate-specific component
DHMILLCL_00703 1.4e-112 2.7.1.48 F uridine kinase
DHMILLCL_00704 2.5e-172 korD 1.2.7.3 C Domain of unknown function (DUF362)
DHMILLCL_00705 6.7e-224 C Na H antiporter family protein
DHMILLCL_00706 1.8e-176 MA20_14895 S Conserved hypothetical protein 698
DHMILLCL_00707 7e-118
DHMILLCL_00708 3.7e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DHMILLCL_00709 3.9e-167 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DHMILLCL_00710 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DHMILLCL_00711 3.1e-144 cobB2 K Sir2 family
DHMILLCL_00713 2.3e-85 I alpha/beta hydrolase fold
DHMILLCL_00714 4.1e-261 G Bacterial extracellular solute-binding protein
DHMILLCL_00715 1.3e-182 K helix_turn _helix lactose operon repressor
DHMILLCL_00716 2e-108 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DHMILLCL_00717 4.3e-259 EGP Transmembrane secretion effector
DHMILLCL_00718 8.6e-56 KLT Protein tyrosine kinase
DHMILLCL_00719 1.9e-189 K Periplasmic binding protein domain
DHMILLCL_00720 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DHMILLCL_00721 8.9e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DHMILLCL_00722 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DHMILLCL_00723 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
DHMILLCL_00724 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
DHMILLCL_00725 6.4e-128 pknD ET ABC transporter, substrate-binding protein, family 3
DHMILLCL_00726 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
DHMILLCL_00727 1.1e-156 pknD ET ABC transporter, substrate-binding protein, family 3
DHMILLCL_00728 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DHMILLCL_00729 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
DHMILLCL_00730 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DHMILLCL_00731 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
DHMILLCL_00732 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DHMILLCL_00733 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DHMILLCL_00734 1.7e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DHMILLCL_00735 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DHMILLCL_00736 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
DHMILLCL_00737 0.0 pepO 3.4.24.71 O Peptidase family M13
DHMILLCL_00738 1.4e-98 L Single-strand binding protein family
DHMILLCL_00739 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DHMILLCL_00740 8.7e-270 recD2 3.6.4.12 L PIF1-like helicase
DHMILLCL_00741 2.5e-161 supH S Sucrose-6F-phosphate phosphohydrolase
DHMILLCL_00742 3.1e-121 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DHMILLCL_00743 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DHMILLCL_00744 5.8e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DHMILLCL_00745 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
DHMILLCL_00746 1.9e-124 livF E ATPases associated with a variety of cellular activities
DHMILLCL_00747 1.8e-150 E Branched-chain amino acid ATP-binding cassette transporter
DHMILLCL_00748 1.4e-196 livM U Belongs to the binding-protein-dependent transport system permease family
DHMILLCL_00749 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
DHMILLCL_00750 7.8e-219 livK E Receptor family ligand binding region
DHMILLCL_00751 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DHMILLCL_00752 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DHMILLCL_00753 1.5e-35 rpmE J Binds the 23S rRNA
DHMILLCL_00755 6.8e-226 xylR GK ROK family
DHMILLCL_00756 2.9e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DHMILLCL_00757 2.1e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DHMILLCL_00758 9.7e-09 CE10 I Belongs to the type-B carboxylesterase lipase family
DHMILLCL_00759 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DHMILLCL_00760 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DHMILLCL_00761 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_00762 1.3e-185 MA20_14025 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_00763 2.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
DHMILLCL_00764 2.1e-188 K Bacterial regulatory proteins, lacI family
DHMILLCL_00765 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
DHMILLCL_00766 1.3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DHMILLCL_00767 3.5e-249 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
DHMILLCL_00768 1.3e-279 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DHMILLCL_00769 1.5e-107 S Membrane
DHMILLCL_00770 1.1e-133 ydcZ S Putative inner membrane exporter, YdcZ
DHMILLCL_00771 9.3e-88 ykoE S ABC-type cobalt transport system, permease component
DHMILLCL_00772 4.7e-227 xylR GK ROK family
DHMILLCL_00773 1.7e-290 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DHMILLCL_00774 5.2e-167 F Inosine-uridine preferring nucleoside hydrolase
DHMILLCL_00775 2.4e-214 bdhA C Iron-containing alcohol dehydrogenase
DHMILLCL_00776 8.6e-09 bdhA C Iron-containing alcohol dehydrogenase
DHMILLCL_00777 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DHMILLCL_00778 1e-181 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
DHMILLCL_00779 3.6e-10 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
DHMILLCL_00780 0.0 O Highly conserved protein containing a thioredoxin domain
DHMILLCL_00781 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DHMILLCL_00782 0.0 G Psort location Cytoplasmic, score 8.87
DHMILLCL_00783 4.3e-150 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_00784 2.1e-174 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_00785 5.1e-256 G ABC transporter periplasmic binding protein YcjN precursor K02027
DHMILLCL_00786 2.3e-98 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
DHMILLCL_00787 9.3e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DHMILLCL_00788 5.9e-182 V Beta-lactamase
DHMILLCL_00789 0.0 yjjK S ATP-binding cassette protein, ChvD family
DHMILLCL_00790 5e-165 tesB I Thioesterase-like superfamily
DHMILLCL_00791 6.8e-93 S Protein of unknown function (DUF3180)
DHMILLCL_00792 2.4e-273 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DHMILLCL_00793 1e-154 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DHMILLCL_00794 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DHMILLCL_00795 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DHMILLCL_00796 8.6e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DHMILLCL_00797 1.5e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DHMILLCL_00798 4.4e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DHMILLCL_00799 6.3e-232 epsG M Glycosyl transferase family 21
DHMILLCL_00800 2.9e-234 S AI-2E family transporter
DHMILLCL_00801 2.5e-180 3.4.14.13 M Glycosyltransferase like family 2
DHMILLCL_00802 8.9e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DHMILLCL_00803 0.0 yliE T Putative diguanylate phosphodiesterase
DHMILLCL_00804 8.5e-111 S Domain of unknown function (DUF4956)
DHMILLCL_00805 1.4e-158 P VTC domain
DHMILLCL_00806 0.0 cotH M CotH kinase protein
DHMILLCL_00807 5.4e-281 pelG S Putative exopolysaccharide Exporter (EPS-E)
DHMILLCL_00808 2.6e-277 pelF GT4 M Domain of unknown function (DUF3492)
DHMILLCL_00809 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
DHMILLCL_00810 7.4e-153
DHMILLCL_00811 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
DHMILLCL_00815 7.7e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DHMILLCL_00816 7.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DHMILLCL_00818 3.6e-85 ptpA 3.1.3.48 T low molecular weight
DHMILLCL_00819 2.4e-129 folA 1.5.1.3 H dihydrofolate reductase
DHMILLCL_00820 8.4e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DHMILLCL_00821 1e-72 attW O OsmC-like protein
DHMILLCL_00822 1.3e-190 T Universal stress protein family
DHMILLCL_00823 1.3e-79 M NlpC/P60 family
DHMILLCL_00824 1.8e-165 usp 3.5.1.28 CBM50 S CHAP domain
DHMILLCL_00825 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DHMILLCL_00826 6.2e-41
DHMILLCL_00827 1.4e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DHMILLCL_00828 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
DHMILLCL_00829 0.0 4.2.1.53 S MCRA family
DHMILLCL_00830 3e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DHMILLCL_00831 5.6e-203 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DHMILLCL_00832 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DHMILLCL_00834 2.4e-212 araJ EGP Major facilitator Superfamily
DHMILLCL_00835 0.0 S Domain of unknown function (DUF4037)
DHMILLCL_00836 6.7e-116 S Protein of unknown function (DUF4125)
DHMILLCL_00837 4.6e-92
DHMILLCL_00838 5.7e-147 pspC KT PspC domain
DHMILLCL_00839 2.6e-259 tcsS3 KT PspC domain
DHMILLCL_00840 5.6e-121 degU K helix_turn_helix, Lux Regulon
DHMILLCL_00841 2.8e-102 Q Isochorismatase family
DHMILLCL_00842 6.9e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
DHMILLCL_00843 8.3e-190 yegV G pfkB family carbohydrate kinase
DHMILLCL_00844 4.6e-188 yegU O ADP-ribosylglycohydrolase
DHMILLCL_00846 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DHMILLCL_00847 8.3e-199 I Diacylglycerol kinase catalytic domain
DHMILLCL_00848 2.8e-157 arbG K CAT RNA binding domain
DHMILLCL_00849 0.0 crr G pts system, glucose-specific IIABC component
DHMILLCL_00850 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DHMILLCL_00851 8e-151 T LytTr DNA-binding domain
DHMILLCL_00852 5.7e-250 T GHKL domain
DHMILLCL_00853 7.3e-212 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHMILLCL_00854 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DHMILLCL_00856 2.8e-106
DHMILLCL_00857 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DHMILLCL_00858 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DHMILLCL_00859 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DHMILLCL_00860 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DHMILLCL_00861 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DHMILLCL_00862 6.1e-191 nusA K Participates in both transcription termination and antitermination
DHMILLCL_00863 4.4e-78
DHMILLCL_00865 1.5e-45 E Transglutaminase/protease-like homologues
DHMILLCL_00866 1.1e-42 gcs2 S A circularly permuted ATPgrasp
DHMILLCL_00867 2e-169 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DHMILLCL_00868 7.8e-64 rplQ J Ribosomal protein L17
DHMILLCL_00869 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHMILLCL_00870 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DHMILLCL_00871 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DHMILLCL_00872 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DHMILLCL_00873 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DHMILLCL_00874 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DHMILLCL_00875 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DHMILLCL_00876 9.8e-74 rplO J binds to the 23S rRNA
DHMILLCL_00877 3.4e-25 rpmD J Ribosomal protein L30p/L7e
DHMILLCL_00878 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DHMILLCL_00879 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DHMILLCL_00880 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DHMILLCL_00881 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DHMILLCL_00882 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DHMILLCL_00883 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DHMILLCL_00884 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DHMILLCL_00885 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DHMILLCL_00886 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DHMILLCL_00887 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
DHMILLCL_00888 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DHMILLCL_00889 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DHMILLCL_00890 5.7e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DHMILLCL_00891 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DHMILLCL_00892 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DHMILLCL_00893 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DHMILLCL_00894 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
DHMILLCL_00895 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DHMILLCL_00896 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
DHMILLCL_00897 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DHMILLCL_00898 4.7e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
DHMILLCL_00899 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
DHMILLCL_00900 1.6e-238 EGP Major facilitator Superfamily
DHMILLCL_00901 2e-216 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DHMILLCL_00902 3.2e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DHMILLCL_00903 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DHMILLCL_00904 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
DHMILLCL_00905 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DHMILLCL_00906 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DHMILLCL_00907 3.1e-122
DHMILLCL_00908 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DHMILLCL_00909 3.6e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DHMILLCL_00910 1e-254 M Bacterial capsule synthesis protein PGA_cap
DHMILLCL_00911 8.8e-224 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DHMILLCL_00913 2.4e-294 CE10 I Belongs to the type-B carboxylesterase lipase family
DHMILLCL_00914 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
DHMILLCL_00915 5.9e-232 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
DHMILLCL_00916 0.0 G Psort location Cytoplasmic, score 8.87
DHMILLCL_00918 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DHMILLCL_00919 7.4e-152 dppF E ABC transporter
DHMILLCL_00920 1.8e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
DHMILLCL_00921 6e-142 EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_00922 4.5e-180 EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_00923 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
DHMILLCL_00924 3.3e-206 dapC E Aminotransferase class I and II
DHMILLCL_00925 8.3e-59 fdxA C 4Fe-4S binding domain
DHMILLCL_00926 2.8e-266 E aromatic amino acid transport protein AroP K03293
DHMILLCL_00927 1.9e-204 murB 1.3.1.98 M Cell wall formation
DHMILLCL_00928 5.5e-25 rpmG J Ribosomal protein L33
DHMILLCL_00932 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DHMILLCL_00933 4.7e-147
DHMILLCL_00934 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DHMILLCL_00935 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DHMILLCL_00936 6.1e-30 fmdB S Putative regulatory protein
DHMILLCL_00937 1.1e-92 flgA NO SAF
DHMILLCL_00938 4.8e-36
DHMILLCL_00939 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DHMILLCL_00940 3.6e-175 T Forkhead associated domain
DHMILLCL_00941 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DHMILLCL_00942 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DHMILLCL_00943 1.3e-246 pbuO S Permease family
DHMILLCL_00944 1.8e-143 P Zinc-uptake complex component A periplasmic
DHMILLCL_00945 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DHMILLCL_00946 1.5e-167 pstA P Phosphate transport system permease
DHMILLCL_00947 6.8e-165 pstC P probably responsible for the translocation of the substrate across the membrane
DHMILLCL_00948 1.3e-199 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DHMILLCL_00949 3.4e-129 KT Transcriptional regulatory protein, C terminal
DHMILLCL_00950 6.9e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DHMILLCL_00951 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DHMILLCL_00952 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DHMILLCL_00953 1.7e-210 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DHMILLCL_00954 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
DHMILLCL_00955 1.3e-58 D nuclear chromosome segregation
DHMILLCL_00956 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DHMILLCL_00957 2.5e-144 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DHMILLCL_00958 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DHMILLCL_00959 7e-297 yegQ O Peptidase family U32 C-terminal domain
DHMILLCL_00960 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DHMILLCL_00961 0.0 S Predicted membrane protein (DUF2207)
DHMILLCL_00962 8.5e-91 lemA S LemA family
DHMILLCL_00963 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DHMILLCL_00964 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DHMILLCL_00965 1.1e-116
DHMILLCL_00967 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
DHMILLCL_00968 4.5e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DHMILLCL_00970 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
DHMILLCL_00971 0.0 pccB I Carboxyl transferase domain
DHMILLCL_00972 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DHMILLCL_00973 6e-79 bioY S BioY family
DHMILLCL_00974 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DHMILLCL_00975 0.0
DHMILLCL_00976 5.9e-143 QT PucR C-terminal helix-turn-helix domain
DHMILLCL_00977 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DHMILLCL_00978 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DHMILLCL_00979 4.2e-128 nusG K Participates in transcription elongation, termination and antitermination
DHMILLCL_00980 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DHMILLCL_00982 9.7e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DHMILLCL_00983 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DHMILLCL_00984 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DHMILLCL_00985 2.6e-39 rpmA J Ribosomal L27 protein
DHMILLCL_00986 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DHMILLCL_00987 8.5e-301 rne 3.1.26.12 J Ribonuclease E/G family
DHMILLCL_00988 3.1e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
DHMILLCL_00989 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DHMILLCL_00990 2.5e-270 V Efflux ABC transporter, permease protein
DHMILLCL_00991 5e-128 V ATPases associated with a variety of cellular activities
DHMILLCL_00992 1.5e-115 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DHMILLCL_00993 6.7e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DHMILLCL_00994 1.5e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DHMILLCL_00995 0.0 pgi 5.3.1.9 G Belongs to the GPI family
DHMILLCL_00996 5.4e-181 S Auxin Efflux Carrier
DHMILLCL_00999 4.2e-218 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DHMILLCL_01000 4e-237 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DHMILLCL_01001 1.1e-250 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DHMILLCL_01002 3.9e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DHMILLCL_01003 3.6e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DHMILLCL_01004 5.4e-77 soxR K MerR, DNA binding
DHMILLCL_01005 8.7e-195 yghZ C Aldo/keto reductase family
DHMILLCL_01006 9.4e-58 S Protein of unknown function (DUF3039)
DHMILLCL_01007 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DHMILLCL_01008 8.5e-134
DHMILLCL_01009 1.8e-113 yceD S Uncharacterized ACR, COG1399
DHMILLCL_01010 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DHMILLCL_01011 5.7e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DHMILLCL_01012 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DHMILLCL_01013 5.7e-92 ilvN 2.2.1.6 E ACT domain
DHMILLCL_01014 2.1e-94
DHMILLCL_01015 0.0 yjjK S ABC transporter
DHMILLCL_01016 1.6e-151 guaA1 6.3.5.2 F Peptidase C26
DHMILLCL_01017 2.7e-294 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DHMILLCL_01018 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DHMILLCL_01019 4e-179 S Endonuclease/Exonuclease/phosphatase family
DHMILLCL_01020 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DHMILLCL_01021 1.8e-34 CP_0960 S Belongs to the UPF0109 family
DHMILLCL_01022 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DHMILLCL_01023 3.2e-151 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DHMILLCL_01024 6.5e-105 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DHMILLCL_01025 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DHMILLCL_01026 8.4e-30 rpmB J Ribosomal L28 family
DHMILLCL_01027 0.0 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01028 4.9e-230 yxiO S Vacuole effluxer Atg22 like
DHMILLCL_01029 1.9e-127 gntR K FCD
DHMILLCL_01030 1.8e-77 gntK 2.7.1.12 F Shikimate kinase
DHMILLCL_01031 8.8e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DHMILLCL_01032 6.3e-125 K Bacterial regulatory proteins, tetR family
DHMILLCL_01033 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01034 5.9e-230 MA20_36090 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01035 1.7e-137 M Mechanosensitive ion channel
DHMILLCL_01036 4e-177 S CAAX protease self-immunity
DHMILLCL_01037 7.5e-214 3.6.3.30 E Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
DHMILLCL_01038 4.7e-141 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_01039 1.4e-157 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_01040 5.8e-219 P Bacterial extracellular solute-binding protein
DHMILLCL_01041 5.5e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DHMILLCL_01042 6.6e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DHMILLCL_01043 5.5e-177 plsC2 2.3.1.51 I Phosphate acyltransferases
DHMILLCL_01044 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DHMILLCL_01045 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
DHMILLCL_01046 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DHMILLCL_01047 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DHMILLCL_01048 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DHMILLCL_01049 1.3e-279 S Calcineurin-like phosphoesterase
DHMILLCL_01052 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DHMILLCL_01053 1.2e-111 S Protein of unknown function (DUF805)
DHMILLCL_01054 7e-184
DHMILLCL_01055 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DHMILLCL_01056 2.1e-263 EGP Major facilitator Superfamily
DHMILLCL_01057 7.1e-95 S GtrA-like protein
DHMILLCL_01058 6.7e-62 S Macrophage migration inhibitory factor (MIF)
DHMILLCL_01059 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DHMILLCL_01060 0.0 pepD E Peptidase family C69
DHMILLCL_01061 1.1e-106 S Phosphatidylethanolamine-binding protein
DHMILLCL_01062 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DHMILLCL_01063 6e-39 ptsH G PTS HPr component phosphorylation site
DHMILLCL_01064 7.6e-186 K helix_turn _helix lactose operon repressor
DHMILLCL_01065 1.3e-191 holB 2.7.7.7 L DNA polymerase III
DHMILLCL_01066 1.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DHMILLCL_01067 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DHMILLCL_01068 3.1e-190 3.6.1.27 I PAP2 superfamily
DHMILLCL_01069 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
DHMILLCL_01070 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
DHMILLCL_01071 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DHMILLCL_01072 0.0 S Beta-L-arabinofuranosidase, GH127
DHMILLCL_01073 1.9e-156 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_01074 9.1e-170 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01075 4.8e-246 G Bacterial extracellular solute-binding protein
DHMILLCL_01076 2.3e-203 abf G Glycosyl hydrolases family 43
DHMILLCL_01077 1.9e-195 K helix_turn _helix lactose operon repressor
DHMILLCL_01078 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
DHMILLCL_01079 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DHMILLCL_01080 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DHMILLCL_01081 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DHMILLCL_01082 4.6e-299 S Calcineurin-like phosphoesterase
DHMILLCL_01083 2.4e-115
DHMILLCL_01084 2.1e-38
DHMILLCL_01085 2.8e-30 K helix_turn_helix, Lux Regulon
DHMILLCL_01086 1.1e-06 2.7.13.3 T Histidine kinase
DHMILLCL_01087 1.3e-23 S Protein of unknown function (DUF1778)
DHMILLCL_01088 5.9e-46 K Acetyltransferase (GNAT) family
DHMILLCL_01089 9.2e-160 K Periplasmic binding protein domain
DHMILLCL_01090 1e-126 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01091 5.7e-156 malC G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01092 4.1e-232 G Bacterial extracellular solute-binding protein
DHMILLCL_01093 1.9e-271 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01094 0.0 3.2.1.22 G lipolytic protein G-D-S-L family
DHMILLCL_01095 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DHMILLCL_01096 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
DHMILLCL_01097 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DHMILLCL_01098 1e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DHMILLCL_01099 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DHMILLCL_01100 1.1e-96 K Bacterial regulatory proteins, tetR family
DHMILLCL_01101 1.6e-193 S Psort location CytoplasmicMembrane, score
DHMILLCL_01102 4.9e-218 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DHMILLCL_01103 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
DHMILLCL_01104 1.1e-59 U TadE-like protein
DHMILLCL_01105 1.3e-42 S Protein of unknown function (DUF4244)
DHMILLCL_01106 6.1e-91 gspF NU Type II secretion system (T2SS), protein F
DHMILLCL_01107 1.2e-132 U Type ii secretion system
DHMILLCL_01108 8e-185 cpaF U Type II IV secretion system protein
DHMILLCL_01109 6.1e-140 cpaE D bacterial-type flagellum organization
DHMILLCL_01110 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DHMILLCL_01111 1.3e-223 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DHMILLCL_01112 3.9e-91
DHMILLCL_01113 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DHMILLCL_01114 6.7e-206 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DHMILLCL_01115 0.0 G Bacterial Ig-like domain (group 4)
DHMILLCL_01116 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
DHMILLCL_01117 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DHMILLCL_01118 9.3e-147 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01119 3.1e-167 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01120 4.3e-07 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01121 2.5e-242 G Bacterial extracellular solute-binding protein
DHMILLCL_01122 1.4e-192 K Periplasmic binding protein domain
DHMILLCL_01123 0.0 ubiB S ABC1 family
DHMILLCL_01124 1e-27 S granule-associated protein
DHMILLCL_01125 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DHMILLCL_01126 2.5e-251 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DHMILLCL_01127 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DHMILLCL_01128 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DHMILLCL_01129 1e-54 glnB K Nitrogen regulatory protein P-II
DHMILLCL_01130 1.2e-236 amt U Ammonium Transporter Family
DHMILLCL_01131 2.1e-166 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DHMILLCL_01132 1.1e-107 icaR K Bacterial regulatory proteins, tetR family
DHMILLCL_01134 6.1e-196 XK27_01805 M Glycosyltransferase like family 2
DHMILLCL_01135 2.4e-303 pepD E Peptidase family C69
DHMILLCL_01137 2.3e-163 M cell wall binding repeat
DHMILLCL_01138 6e-38 nrdH O Glutaredoxin
DHMILLCL_01139 2e-225 S Putative ABC-transporter type IV
DHMILLCL_01140 0.0 pip S YhgE Pip domain protein
DHMILLCL_01141 5.3e-274 pip S YhgE Pip domain protein
DHMILLCL_01142 1.2e-88 K Psort location Cytoplasmic, score 8.87
DHMILLCL_01143 5.3e-61 S FMN_bind
DHMILLCL_01144 9e-150 macB V ABC transporter, ATP-binding protein
DHMILLCL_01145 9.8e-204 Z012_06715 V FtsX-like permease family
DHMILLCL_01147 8e-220 macB_2 V ABC transporter permease
DHMILLCL_01148 1.2e-230 S Predicted membrane protein (DUF2318)
DHMILLCL_01149 1.4e-92 tpd P Fe2+ transport protein
DHMILLCL_01150 1.4e-293 efeU_1 P Iron permease FTR1 family
DHMILLCL_01151 2.2e-201 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DHMILLCL_01152 0.0 lmrA2 V ABC transporter transmembrane region
DHMILLCL_01153 0.0 lmrA1 V ABC transporter, ATP-binding protein
DHMILLCL_01154 1.1e-83 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DHMILLCL_01155 1.5e-205 1.1.1.65 C Aldo/keto reductase family
DHMILLCL_01156 1.9e-26 thiS 2.8.1.10 H ThiS family
DHMILLCL_01157 8.4e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
DHMILLCL_01158 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DHMILLCL_01159 3.7e-282 cycA E Amino acid permease
DHMILLCL_01160 1.9e-84 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01161 7.6e-211 M LPXTG cell wall anchor motif
DHMILLCL_01162 0.0 inlJ M domain protein
DHMILLCL_01163 1.3e-183 3.4.22.70 M Sortase family
DHMILLCL_01164 1.3e-76 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01165 3.3e-227 P Sodium/hydrogen exchanger family
DHMILLCL_01166 0.0 V FtsX-like permease family
DHMILLCL_01167 9.1e-270 aroP E aromatic amino acid transport protein AroP K03293
DHMILLCL_01168 8.3e-12 S Protein of unknown function, DUF624
DHMILLCL_01169 2.5e-189 K helix_turn _helix lactose operon repressor
DHMILLCL_01170 2.4e-38 G beta-mannosidase
DHMILLCL_01171 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DHMILLCL_01172 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DHMILLCL_01173 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DHMILLCL_01174 7.9e-252 yhjE EGP Sugar (and other) transporter
DHMILLCL_01175 5.9e-267 scrT G Transporter major facilitator family protein
DHMILLCL_01176 1.6e-149 amyC5 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01177 2.9e-162 amyD3 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01178 3.8e-219 G Bacterial extracellular solute-binding protein
DHMILLCL_01179 0.0 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
DHMILLCL_01180 1.5e-115 S Protein of unknown function, DUF624
DHMILLCL_01181 1.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DHMILLCL_01182 1.4e-195 K helix_turn _helix lactose operon repressor
DHMILLCL_01183 1.4e-29 E Receptor family ligand binding region
DHMILLCL_01184 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHMILLCL_01185 2e-145 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DHMILLCL_01186 7.2e-297 clcA P Voltage gated chloride channel
DHMILLCL_01187 2.6e-252 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DHMILLCL_01188 4.1e-206 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DHMILLCL_01189 0.0 pip S YhgE Pip domain protein
DHMILLCL_01190 0.0 pip S YhgE Pip domain protein
DHMILLCL_01191 2.7e-169 yddG EG EamA-like transporter family
DHMILLCL_01192 4.6e-185 K Helix-turn-helix XRE-family like proteins
DHMILLCL_01194 2.3e-161 htpX O Belongs to the peptidase M48B family
DHMILLCL_01195 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DHMILLCL_01196 6.7e-187 ansA 3.5.1.1 EJ Asparaginase
DHMILLCL_01197 0.0 cadA P E1-E2 ATPase
DHMILLCL_01198 3.6e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DHMILLCL_01199 9.4e-269 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DHMILLCL_01200 2.4e-22 2.7.13.3 T Histidine kinase
DHMILLCL_01205 8.8e-160 yicL EG EamA-like transporter family
DHMILLCL_01206 1.5e-192 pldB 3.1.1.5 I Serine aminopeptidase, S33
DHMILLCL_01207 3.2e-113 K helix_turn_helix, Lux Regulon
DHMILLCL_01208 2.3e-224 2.7.13.3 T Histidine kinase
DHMILLCL_01209 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DHMILLCL_01210 1.2e-131 fhaA T Protein of unknown function (DUF2662)
DHMILLCL_01211 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DHMILLCL_01212 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DHMILLCL_01213 1.3e-271 rodA D Belongs to the SEDS family
DHMILLCL_01214 8e-266 pbpA M penicillin-binding protein
DHMILLCL_01215 5.8e-177 T Protein tyrosine kinase
DHMILLCL_01216 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DHMILLCL_01217 1.7e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DHMILLCL_01218 6.7e-209 srtA 3.4.22.70 M Sortase family
DHMILLCL_01219 6.8e-142 S Bacterial protein of unknown function (DUF881)
DHMILLCL_01220 3.1e-57 crgA D Involved in cell division
DHMILLCL_01221 3.1e-234 L ribosomal rna small subunit methyltransferase
DHMILLCL_01222 1.1e-147 gluP 3.4.21.105 S Rhomboid family
DHMILLCL_01223 1.9e-33
DHMILLCL_01224 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DHMILLCL_01225 1.7e-63 I Sterol carrier protein
DHMILLCL_01226 1.4e-41 S Protein of unknown function (DUF3073)
DHMILLCL_01227 1.7e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DHMILLCL_01228 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DHMILLCL_01229 0.0 yjjP S Threonine/Serine exporter, ThrE
DHMILLCL_01230 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DHMILLCL_01231 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DHMILLCL_01232 2.3e-240 ytfL P Transporter associated domain
DHMILLCL_01233 4.1e-189 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DHMILLCL_01234 3.1e-101 S Protein of unknown function DUF45
DHMILLCL_01238 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DHMILLCL_01239 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DHMILLCL_01240 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
DHMILLCL_01241 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHMILLCL_01242 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DHMILLCL_01243 6.2e-90 S Protein of unknown function (DUF721)
DHMILLCL_01244 8.2e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DHMILLCL_01245 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DHMILLCL_01246 2.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DHMILLCL_01247 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
DHMILLCL_01248 7.3e-189 yidC U Membrane protein insertase, YidC Oxa1 family
DHMILLCL_01249 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
DHMILLCL_01250 4.3e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DHMILLCL_01251 2.5e-170 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DHMILLCL_01252 1.5e-202 parB K Belongs to the ParB family
DHMILLCL_01253 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DHMILLCL_01254 7e-14 S Psort location Extracellular, score 8.82
DHMILLCL_01256 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DHMILLCL_01257 4e-13 S Domain of unknown function (DUF4143)
DHMILLCL_01258 0.0 murJ KLT MviN-like protein
DHMILLCL_01259 1e-304 murJ KLT MviN-like protein
DHMILLCL_01260 0.0 M Conserved repeat domain
DHMILLCL_01261 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DHMILLCL_01262 3.8e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DHMILLCL_01263 2.6e-109 S LytR cell envelope-related transcriptional attenuator
DHMILLCL_01264 9.6e-169 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DHMILLCL_01265 7.8e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DHMILLCL_01266 2.8e-197 S G5
DHMILLCL_01268 2.2e-150 O Thioredoxin
DHMILLCL_01269 0.0 KLT Protein tyrosine kinase
DHMILLCL_01270 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
DHMILLCL_01271 4.5e-167 G ABC transporter permease
DHMILLCL_01272 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01273 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
DHMILLCL_01274 2.2e-246 G Bacterial extracellular solute-binding protein
DHMILLCL_01275 1.8e-275 G Bacterial extracellular solute-binding protein
DHMILLCL_01276 5.9e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DHMILLCL_01277 1.6e-241 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DHMILLCL_01278 8.7e-293 E ABC transporter, substrate-binding protein, family 5
DHMILLCL_01279 4.8e-166 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01280 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
DHMILLCL_01281 1.4e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DHMILLCL_01282 4e-139 sapF E ATPases associated with a variety of cellular activities
DHMILLCL_01283 1.3e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DHMILLCL_01284 3.8e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DHMILLCL_01285 0.0 macB_2 V ATPases associated with a variety of cellular activities
DHMILLCL_01286 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DHMILLCL_01287 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DHMILLCL_01288 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DHMILLCL_01289 3.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
DHMILLCL_01290 2e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DHMILLCL_01291 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DHMILLCL_01292 2e-214 ybiR P Citrate transporter
DHMILLCL_01294 7.5e-175 ydcZ S Putative inner membrane exporter, YdcZ
DHMILLCL_01296 0.0 tetP J Elongation factor G, domain IV
DHMILLCL_01300 2.7e-114 K acetyltransferase
DHMILLCL_01301 6.2e-109 papP E Binding-protein-dependent transport system inner membrane component
DHMILLCL_01302 3.6e-120 E Binding-protein-dependent transport system inner membrane component
DHMILLCL_01303 7.1e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
DHMILLCL_01304 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
DHMILLCL_01305 7.7e-199 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DHMILLCL_01306 2.9e-154 metQ M NLPA lipoprotein
DHMILLCL_01307 7.7e-194 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DHMILLCL_01308 3.2e-97 metI P Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01309 4.8e-221 mtnE 2.6.1.83 E Aminotransferase class I and II
DHMILLCL_01310 1.2e-74 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DHMILLCL_01311 2.8e-15 P Belongs to the ABC transporter superfamily
DHMILLCL_01312 1.4e-43 XAC3035 O Glutaredoxin
DHMILLCL_01313 3.1e-127 XK27_08050 O prohibitin homologues
DHMILLCL_01314 1.7e-13 S Domain of unknown function (DUF4143)
DHMILLCL_01315 4.3e-75
DHMILLCL_01316 3.4e-129 V ATPases associated with a variety of cellular activities
DHMILLCL_01317 6.3e-146 M Conserved repeat domain
DHMILLCL_01318 4.4e-256 macB_8 V MacB-like periplasmic core domain
DHMILLCL_01319 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DHMILLCL_01320 1.2e-183 adh3 C Zinc-binding dehydrogenase
DHMILLCL_01321 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DHMILLCL_01322 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DHMILLCL_01323 2.3e-89 zur P Belongs to the Fur family
DHMILLCL_01324 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DHMILLCL_01325 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DHMILLCL_01326 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DHMILLCL_01327 1.3e-128 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
DHMILLCL_01328 7.4e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
DHMILLCL_01329 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DHMILLCL_01330 2.1e-247 EGP Major facilitator Superfamily
DHMILLCL_01331 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
DHMILLCL_01332 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DHMILLCL_01333 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DHMILLCL_01334 9.6e-257 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DHMILLCL_01335 1.2e-24
DHMILLCL_01336 1.3e-119 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
DHMILLCL_01338 1.1e-12
DHMILLCL_01339 3.5e-39 S Domain of unknown function (DUF4839)
DHMILLCL_01340 8.4e-36
DHMILLCL_01341 2e-203 S Short C-terminal domain
DHMILLCL_01342 3.2e-136
DHMILLCL_01343 4.9e-100 S Protein of unknown function (DUF4230)
DHMILLCL_01346 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DHMILLCL_01347 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DHMILLCL_01348 1.1e-228 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DHMILLCL_01349 6.5e-226 M Glycosyl transferase 4-like domain
DHMILLCL_01350 8.5e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
DHMILLCL_01352 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
DHMILLCL_01354 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DHMILLCL_01355 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DHMILLCL_01356 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DHMILLCL_01357 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DHMILLCL_01358 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DHMILLCL_01359 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DHMILLCL_01360 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
DHMILLCL_01361 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DHMILLCL_01362 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DHMILLCL_01363 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DHMILLCL_01365 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DHMILLCL_01366 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DHMILLCL_01367 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DHMILLCL_01368 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DHMILLCL_01369 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DHMILLCL_01370 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DHMILLCL_01371 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DHMILLCL_01372 4.4e-283 arc O AAA ATPase forming ring-shaped complexes
DHMILLCL_01373 1.1e-300 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DHMILLCL_01374 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
DHMILLCL_01375 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DHMILLCL_01376 2.6e-280 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DHMILLCL_01377 9.7e-141 C FMN binding
DHMILLCL_01378 1.8e-57
DHMILLCL_01379 1.4e-41 hup L Belongs to the bacterial histone-like protein family
DHMILLCL_01380 0.0 S Lysylphosphatidylglycerol synthase TM region
DHMILLCL_01381 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DHMILLCL_01382 1e-276 S PGAP1-like protein
DHMILLCL_01383 1.3e-62
DHMILLCL_01384 5e-182 S von Willebrand factor (vWF) type A domain
DHMILLCL_01385 2e-189 S von Willebrand factor (vWF) type A domain
DHMILLCL_01386 3.6e-91
DHMILLCL_01387 5.5e-175 S Protein of unknown function DUF58
DHMILLCL_01388 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
DHMILLCL_01389 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DHMILLCL_01390 8.5e-77 S LytR cell envelope-related transcriptional attenuator
DHMILLCL_01391 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DHMILLCL_01393 1.3e-124
DHMILLCL_01394 2.6e-132 KT Response regulator receiver domain protein
DHMILLCL_01395 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DHMILLCL_01396 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
DHMILLCL_01397 1.2e-182 S Protein of unknown function (DUF3027)
DHMILLCL_01398 4.6e-188 uspA T Belongs to the universal stress protein A family
DHMILLCL_01399 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DHMILLCL_01400 8.3e-254 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
DHMILLCL_01401 4.7e-285 purR QT Purine catabolism regulatory protein-like family
DHMILLCL_01402 2.5e-245 proP EGP Sugar (and other) transporter
DHMILLCL_01403 4.6e-140 3.5.2.10 S Creatinine amidohydrolase
DHMILLCL_01404 2.6e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DHMILLCL_01405 5.8e-250 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DHMILLCL_01406 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DHMILLCL_01407 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
DHMILLCL_01408 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
DHMILLCL_01409 1.4e-136 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DHMILLCL_01410 1.4e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
DHMILLCL_01411 3.1e-111 gluC E Binding-protein-dependent transport system inner membrane component
DHMILLCL_01412 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
DHMILLCL_01413 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DHMILLCL_01414 0.0 L DEAD DEAH box helicase
DHMILLCL_01415 2.4e-251 rarA L Recombination factor protein RarA
DHMILLCL_01416 2.9e-258 EGP Major facilitator Superfamily
DHMILLCL_01417 9.2e-311 E ABC transporter, substrate-binding protein, family 5
DHMILLCL_01418 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DHMILLCL_01419 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DHMILLCL_01420 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DHMILLCL_01423 3.6e-244 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DHMILLCL_01424 4.8e-117 safC S O-methyltransferase
DHMILLCL_01425 5.2e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DHMILLCL_01426 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DHMILLCL_01427 5.9e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DHMILLCL_01428 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
DHMILLCL_01429 1.5e-82 yraN L Belongs to the UPF0102 family
DHMILLCL_01430 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DHMILLCL_01431 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
DHMILLCL_01432 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
DHMILLCL_01433 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
DHMILLCL_01434 6.9e-150 P Cobalt transport protein
DHMILLCL_01435 8.2e-193 K helix_turn_helix ASNC type
DHMILLCL_01436 5.1e-142 V ABC transporter, ATP-binding protein
DHMILLCL_01437 0.0 MV MacB-like periplasmic core domain
DHMILLCL_01438 9.4e-130 K helix_turn_helix, Lux Regulon
DHMILLCL_01439 0.0 tcsS2 T Histidine kinase
DHMILLCL_01440 1.5e-266 pip 3.4.11.5 S alpha/beta hydrolase fold
DHMILLCL_01441 7.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DHMILLCL_01442 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DHMILLCL_01443 2.5e-239 S HipA-like C-terminal domain
DHMILLCL_01444 1.6e-16 K addiction module antidote protein HigA
DHMILLCL_01445 3e-213 G Transmembrane secretion effector
DHMILLCL_01446 6.6e-119 K Bacterial regulatory proteins, tetR family
DHMILLCL_01447 8e-58 yccF S Inner membrane component domain
DHMILLCL_01448 1e-11
DHMILLCL_01449 1e-42 cysB 4.2.1.22 EGP Major facilitator Superfamily
DHMILLCL_01450 4.5e-26 cysB 4.2.1.22 EGP Major facilitator Superfamily
DHMILLCL_01451 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01452 8.9e-198 K helix_turn _helix lactose operon repressor
DHMILLCL_01453 2.3e-240 mntH P H( )-stimulated, divalent metal cation uptake system
DHMILLCL_01454 8.4e-167 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DHMILLCL_01455 7.8e-116 L Protein of unknown function (DUF1524)
DHMILLCL_01456 6e-233 T Diguanylate cyclase (GGDEF) domain protein
DHMILLCL_01457 5.8e-283 EGP Major facilitator Superfamily
DHMILLCL_01458 2.5e-47
DHMILLCL_01459 5.1e-187 S Endonuclease/Exonuclease/phosphatase family
DHMILLCL_01460 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
DHMILLCL_01461 0.0 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DHMILLCL_01462 3e-198
DHMILLCL_01463 1.7e-139 V Abi-like protein
DHMILLCL_01465 5.9e-40 L Transposase and inactivated derivatives IS30 family
DHMILLCL_01466 2.7e-09 S KAP family P-loop domain
DHMILLCL_01467 1.3e-15 S KAP family P-loop domain
DHMILLCL_01469 1.2e-44 S Bacteriophage abortive infection AbiH
DHMILLCL_01471 9.4e-61 1.13.11.79 C Psort location Cytoplasmic, score 8.87
DHMILLCL_01472 3e-225 1.12.98.1 C Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term
DHMILLCL_01473 2.3e-220 S Polysaccharide biosynthesis protein
DHMILLCL_01474 5.1e-111 S Polysaccharide pyruvyl transferase
DHMILLCL_01475 1.2e-35 S EpsG family
DHMILLCL_01476 1.1e-176 M Glycosyl transferase, family 2
DHMILLCL_01477 1.7e-173 MA20_43635 M Capsular polysaccharide synthesis protein
DHMILLCL_01478 1.1e-147 cps1D M Domain of unknown function (DUF4422)
DHMILLCL_01479 5.3e-153 M Psort location Cytoplasmic, score 8.87
DHMILLCL_01480 1e-207 M Domain of unknown function (DUF1972)
DHMILLCL_01481 3.8e-187 S Glycosyltransferase like family 2
DHMILLCL_01483 4.9e-226 C Polysaccharide pyruvyl transferase
DHMILLCL_01484 2e-51 S Core-2/I-Branching enzyme
DHMILLCL_01485 5.2e-233 S Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01486 1.1e-29 epsJ S Glycosyltransferase like family 2
DHMILLCL_01487 6.5e-54 2.3.1.30 E serine acetyltransferase
DHMILLCL_01488 4.2e-135 L Integrase core domain
DHMILLCL_01489 1.7e-63 L Psort location Cytoplasmic, score 8.87
DHMILLCL_01490 1.5e-237 F Permease family
DHMILLCL_01491 1.7e-265 3.5.4.28, 3.5.4.31 F Amidohydrolase family
DHMILLCL_01492 7.1e-144 S Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01493 1.7e-55 yccF S Inner membrane component domain
DHMILLCL_01494 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
DHMILLCL_01495 2.5e-144 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01496 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
DHMILLCL_01497 2.3e-223 G Bacterial extracellular solute-binding protein
DHMILLCL_01498 7.5e-183 K helix_turn _helix lactose operon repressor
DHMILLCL_01499 1.4e-184 K Psort location Cytoplasmic, score
DHMILLCL_01500 3e-270 G Bacterial extracellular solute-binding protein
DHMILLCL_01501 1.7e-162 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01502 6.5e-148 P Binding-protein-dependent transport system inner membrane component
DHMILLCL_01503 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DHMILLCL_01504 5.5e-246 wcoI DM Psort location CytoplasmicMembrane, score
DHMILLCL_01505 2.6e-97 3.1.3.48 T Low molecular weight phosphatase family
DHMILLCL_01506 1.4e-73
DHMILLCL_01507 1.6e-28 K Cro/C1-type HTH DNA-binding domain
DHMILLCL_01508 1.9e-71
DHMILLCL_01509 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
DHMILLCL_01510 1.8e-158 cps1D M Domain of unknown function (DUF4422)
DHMILLCL_01511 1.1e-189 2.4.1.166 GT2 M Glycosyltransferase like family 2
DHMILLCL_01512 1.2e-255 S Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01513 1.5e-286 S Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01514 4.7e-207 wbbI M transferase activity, transferring glycosyl groups
DHMILLCL_01515 7.1e-192 1.13.11.79 C Psort location Cytoplasmic, score 8.87
DHMILLCL_01516 5.5e-211 GT2 M Glycosyltransferase like family 2
DHMILLCL_01517 2.1e-224 C Polysaccharide pyruvyl transferase
DHMILLCL_01518 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
DHMILLCL_01519 2.1e-88
DHMILLCL_01520 5.6e-170 S G5
DHMILLCL_01521 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DHMILLCL_01522 1.7e-113 F Domain of unknown function (DUF4916)
DHMILLCL_01523 3.4e-160 mhpC I Alpha/beta hydrolase family
DHMILLCL_01524 2.1e-207 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DHMILLCL_01525 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DHMILLCL_01526 1.5e-236 S Uncharacterized conserved protein (DUF2183)
DHMILLCL_01527 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DHMILLCL_01528 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DHMILLCL_01529 1.5e-87 J TM2 domain
DHMILLCL_01530 6.5e-215 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DHMILLCL_01531 5.2e-133 glxR K helix_turn_helix, cAMP Regulatory protein
DHMILLCL_01532 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DHMILLCL_01533 3.9e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DHMILLCL_01534 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DHMILLCL_01535 3.4e-141 glpR K DeoR C terminal sensor domain
DHMILLCL_01536 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DHMILLCL_01537 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DHMILLCL_01538 1.1e-23 lmrB EGP Major facilitator Superfamily
DHMILLCL_01539 7.1e-43 gcvR T Belongs to the UPF0237 family
DHMILLCL_01540 5.5e-253 S UPF0210 protein
DHMILLCL_01541 2.5e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DHMILLCL_01542 1.1e-180 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DHMILLCL_01543 6.8e-100
DHMILLCL_01544 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHMILLCL_01545 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DHMILLCL_01546 2.8e-97 T Forkhead associated domain
DHMILLCL_01547 4.8e-104 B Belongs to the OprB family
DHMILLCL_01548 5.8e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
DHMILLCL_01549 0.0 E Transglutaminase-like superfamily
DHMILLCL_01550 8.3e-221 S Protein of unknown function DUF58
DHMILLCL_01551 1.9e-208 S ATPase family associated with various cellular activities (AAA)
DHMILLCL_01552 0.0 S Fibronectin type 3 domain
DHMILLCL_01553 1.3e-260 KLT Protein tyrosine kinase
DHMILLCL_01554 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DHMILLCL_01555 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DHMILLCL_01556 6.6e-246 G Major Facilitator Superfamily
DHMILLCL_01557 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DHMILLCL_01558 1.1e-38 csoR S Metal-sensitive transcriptional repressor
DHMILLCL_01559 0.0 pacS 3.6.3.54 P E1-E2 ATPase
DHMILLCL_01560 4.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DHMILLCL_01561 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DHMILLCL_01562 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DHMILLCL_01563 2.9e-169
DHMILLCL_01564 0.0 O Type VII secretion system ESX-1, transport TM domain B
DHMILLCL_01565 1e-225 snm S WXG100 protein secretion system (Wss), protein YukD
DHMILLCL_01566 1.1e-47 esxU S Proteins of 100 residues with WXG
DHMILLCL_01567 1.5e-43 S Proteins of 100 residues with WXG
DHMILLCL_01569 1.1e-264 O Subtilase family
DHMILLCL_01570 1.3e-175
DHMILLCL_01571 9.8e-142
DHMILLCL_01572 3.7e-188
DHMILLCL_01573 4.4e-55
DHMILLCL_01574 1e-191
DHMILLCL_01575 1.3e-156 T Forkhead associated domain
DHMILLCL_01576 0.0 eccCa D FtsK/SpoIIIE family
DHMILLCL_01577 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DHMILLCL_01578 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DHMILLCL_01579 5e-290 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
DHMILLCL_01580 1.7e-10
DHMILLCL_01581 8.7e-13
DHMILLCL_01582 1.1e-153 EGP Major facilitator Superfamily
DHMILLCL_01584 5.9e-120 L Phage integrase, N-terminal SAM-like domain
DHMILLCL_01585 1.9e-10
DHMILLCL_01586 2.1e-101
DHMILLCL_01591 0.0 V Type II restriction enzyme, methylase subunits
DHMILLCL_01593 3.3e-28 S Bacterial mobilisation protein (MobC)
DHMILLCL_01594 1.1e-150 ltrBE1 U Relaxase/Mobilisation nuclease domain
DHMILLCL_01595 7.1e-16
DHMILLCL_01596 5.2e-43 K Cro/C1-type HTH DNA-binding domain
DHMILLCL_01597 6.1e-16 S BrnA antitoxin of type II toxin-antitoxin system
DHMILLCL_01598 2.6e-25 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
DHMILLCL_01600 8.9e-57
DHMILLCL_01601 1.5e-300 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DHMILLCL_01602 4.1e-10
DHMILLCL_01603 8.8e-75
DHMILLCL_01604 4.4e-258 S AAA domain
DHMILLCL_01605 1.7e-303 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DHMILLCL_01606 6.3e-155 rfbJ M Glycosyl transferase family 2
DHMILLCL_01607 2.4e-169 S Acyltransferase family
DHMILLCL_01608 3.7e-251
DHMILLCL_01609 0.0 wbbM M Glycosyl transferase family 8
DHMILLCL_01610 1.6e-57 wbbM M Glycosyl transferase family 8
DHMILLCL_01611 2.9e-168 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DHMILLCL_01612 2.9e-129 rgpC U Transport permease protein
DHMILLCL_01613 0.0 wbbM M Glycosyl transferase family 8
DHMILLCL_01614 7.3e-201 1.1.1.22 M UDP binding domain
DHMILLCL_01615 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DHMILLCL_01616 1.7e-254 S Domain of unknown function (DUF4143)
DHMILLCL_01617 9.7e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DHMILLCL_01618 1.2e-61
DHMILLCL_01619 3.3e-197 K helix_turn _helix lactose operon repressor
DHMILLCL_01620 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DHMILLCL_01621 2.5e-259 EGP Major Facilitator Superfamily
DHMILLCL_01622 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DHMILLCL_01623 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DHMILLCL_01624 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
DHMILLCL_01625 1.7e-69 ssb1 L Single-stranded DNA-binding protein
DHMILLCL_01626 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DHMILLCL_01627 1.7e-70 rplI J Binds to the 23S rRNA
DHMILLCL_01629 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DHMILLCL_01630 9.5e-09 M Protein of unknown function (DUF3152)
DHMILLCL_01631 1.1e-79 M Protein of unknown function (DUF3152)
DHMILLCL_01632 1.1e-211 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DHMILLCL_01633 2.5e-80
DHMILLCL_01634 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DHMILLCL_01635 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DHMILLCL_01636 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DHMILLCL_01637 1e-135 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
DHMILLCL_01638 3.1e-168 rmuC S RmuC family
DHMILLCL_01639 7.1e-113 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DHMILLCL_01640 6.9e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DHMILLCL_01641 6.2e-134 K Psort location Cytoplasmic, score
DHMILLCL_01642 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHMILLCL_01643 5.5e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DHMILLCL_01644 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DHMILLCL_01645 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
DHMILLCL_01646 2.1e-51 S Protein of unknown function (DUF2469)
DHMILLCL_01647 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DHMILLCL_01648 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DHMILLCL_01649 3.7e-79 K helix_turn_helix ASNC type
DHMILLCL_01650 1.1e-68 tyrA 5.4.99.5 E Chorismate mutase type II
DHMILLCL_01651 0.0 S domain protein
DHMILLCL_01652 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DHMILLCL_01653 1.3e-287 E Bacterial extracellular solute-binding proteins, family 5 Middle
DHMILLCL_01654 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DHMILLCL_01655 4.9e-134 KT Transcriptional regulatory protein, C terminal
DHMILLCL_01656 4.9e-134
DHMILLCL_01657 9.4e-98 mntP P Probably functions as a manganese efflux pump
DHMILLCL_01658 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DHMILLCL_01659 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DHMILLCL_01660 2.1e-174 M LPXTG-motif cell wall anchor domain protein
DHMILLCL_01661 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
DHMILLCL_01662 5.7e-192 yfdV S Membrane transport protein
DHMILLCL_01663 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DHMILLCL_01664 3.6e-90 L Phage integrase family
DHMILLCL_01665 3.2e-11 xhlB S SPP1 phage holin
DHMILLCL_01666 2.7e-74 3.2.1.20, 3.5.1.28 GH31 V N-acetylmuramoyl-L-alanine amidase
DHMILLCL_01667 5.1e-10
DHMILLCL_01669 3.9e-106
DHMILLCL_01670 5.4e-150 NT phage tail tape measure protein
DHMILLCL_01671 4.5e-37
DHMILLCL_01672 8.3e-55
DHMILLCL_01673 2.6e-60
DHMILLCL_01674 6.7e-36
DHMILLCL_01675 3.3e-42
DHMILLCL_01676 2e-214 S Caudovirus prohead serine protease
DHMILLCL_01677 8.8e-161 S Phage portal protein
DHMILLCL_01678 3.4e-237 S Terminase
DHMILLCL_01679 2.3e-40
DHMILLCL_01680 1.4e-98 L HNH endonuclease
DHMILLCL_01681 3.7e-17 S Helix-turn-helix domain
DHMILLCL_01683 4.6e-15
DHMILLCL_01684 3.8e-26
DHMILLCL_01690 1e-206 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DHMILLCL_01691 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
DHMILLCL_01692 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHMILLCL_01693 2.3e-58 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DHMILLCL_01694 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DHMILLCL_01695 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DHMILLCL_01696 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DHMILLCL_01697 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DHMILLCL_01698 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DHMILLCL_01699 0.0 tetP J elongation factor G
DHMILLCL_01701 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DHMILLCL_01702 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DHMILLCL_01703 5.3e-194
DHMILLCL_01704 1.7e-179
DHMILLCL_01705 6e-169 trxA2 O Tetratricopeptide repeat
DHMILLCL_01706 4.7e-122 cyaA 4.6.1.1 S CYTH
DHMILLCL_01708 7e-60 psp1 3.5.99.10 J Endoribonuclease L-PSP
DHMILLCL_01709 9.8e-272 mmuP E amino acid
DHMILLCL_01710 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DHMILLCL_01711 1.2e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DHMILLCL_01712 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
DHMILLCL_01713 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DHMILLCL_01714 9.1e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DHMILLCL_01715 2.1e-210 K helix_turn _helix lactose operon repressor
DHMILLCL_01716 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DHMILLCL_01717 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
DHMILLCL_01718 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DHMILLCL_01719 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DHMILLCL_01720 0.0 cydD V ABC transporter transmembrane region
DHMILLCL_01721 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DHMILLCL_01722 3e-128 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DHMILLCL_01723 1.6e-239 G Bacterial extracellular solute-binding protein
DHMILLCL_01724 2.8e-51 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01725 4.6e-25 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01726 1.6e-44
DHMILLCL_01727 1e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DHMILLCL_01728 1.9e-62 S Protein of unknown function (DUF4235)
DHMILLCL_01729 2.4e-135 G Phosphoglycerate mutase family
DHMILLCL_01730 3.9e-259 amyE G Bacterial extracellular solute-binding protein
DHMILLCL_01731 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DHMILLCL_01732 6.5e-185 K Periplasmic binding protein-like domain
DHMILLCL_01733 1.7e-182 K Psort location Cytoplasmic, score
DHMILLCL_01734 4.1e-153 msmF G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01735 1.5e-152 rafG G ABC transporter permease
DHMILLCL_01736 1.9e-104 S Protein of unknown function, DUF624
DHMILLCL_01737 2.9e-13 S Transposon-encoded protein TnpV
DHMILLCL_01738 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
DHMILLCL_01739 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DHMILLCL_01740 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
DHMILLCL_01741 4.3e-236 malE G Bacterial extracellular solute-binding protein
DHMILLCL_01742 3.2e-248 malF G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01743 3.5e-163 malG G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01744 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DHMILLCL_01745 5.4e-144 S HAD-hyrolase-like
DHMILLCL_01746 1.4e-142 traX S TraX protein
DHMILLCL_01747 1.3e-193 K Psort location Cytoplasmic, score
DHMILLCL_01748 0.0 M cell wall anchor domain protein
DHMILLCL_01749 2.1e-81 M LPXTG-motif cell wall anchor domain protein
DHMILLCL_01750 9.7e-184 M Cna protein B-type domain
DHMILLCL_01751 3.5e-157 srtC 3.4.22.70 M Sortase family
DHMILLCL_01752 1.5e-124 S membrane transporter protein
DHMILLCL_01753 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
DHMILLCL_01754 0.0 dnaK O Heat shock 70 kDa protein
DHMILLCL_01755 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DHMILLCL_01756 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
DHMILLCL_01757 4.5e-115 hspR K transcriptional regulator, MerR family
DHMILLCL_01758 4.3e-46
DHMILLCL_01759 3.3e-129 S HAD hydrolase, family IA, variant 3
DHMILLCL_01761 5.8e-126 dedA S SNARE associated Golgi protein
DHMILLCL_01762 7.3e-18 3.2.1.78 GH26 G Glycosyl hydrolase family 26
DHMILLCL_01763 1.9e-179 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DHMILLCL_01764 6.6e-107
DHMILLCL_01765 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DHMILLCL_01766 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DHMILLCL_01768 4.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
DHMILLCL_01769 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01770 9.7e-262 lacS G Psort location CytoplasmicMembrane, score 10.00
DHMILLCL_01771 3.1e-209 GK ROK family
DHMILLCL_01772 1.4e-141 G ABC transporter permease
DHMILLCL_01773 0.0 S Psort location CytoplasmicMembrane, score 9.99
DHMILLCL_01774 6.2e-241 V ABC transporter permease
DHMILLCL_01775 1.1e-151 V ABC transporter
DHMILLCL_01776 6.7e-150 T HD domain
DHMILLCL_01777 5.7e-166 S Glutamine amidotransferase domain
DHMILLCL_01778 0.0 kup P Transport of potassium into the cell
DHMILLCL_01779 2.2e-184 tatD L TatD related DNase
DHMILLCL_01780 0.0 G Alpha-L-arabinofuranosidase C-terminus
DHMILLCL_01781 1.5e-232 G Alpha galactosidase A
DHMILLCL_01782 1.8e-218 K helix_turn _helix lactose operon repressor
DHMILLCL_01783 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01784 8e-126
DHMILLCL_01785 0.0 yknV V ABC transporter
DHMILLCL_01786 0.0 mdlA2 V ABC transporter
DHMILLCL_01787 1.1e-214 lipA I Hydrolase, alpha beta domain protein
DHMILLCL_01788 5e-27 S Psort location Cytoplasmic, score 8.87
DHMILLCL_01789 3.8e-156 I alpha/beta hydrolase fold
DHMILLCL_01790 3e-239 M Protein of unknown function (DUF2961)
DHMILLCL_01791 0.0 M probably involved in cell wall
DHMILLCL_01792 3.7e-246 3.2.1.14 GH18 S Carbohydrate binding domain
DHMILLCL_01793 0.0 T Diguanylate cyclase, GGDEF domain
DHMILLCL_01794 1.3e-108 T Diguanylate cyclase, GGDEF domain
DHMILLCL_01795 3.9e-187 lacR K Transcriptional regulator, LacI family
DHMILLCL_01796 6.9e-232 nagA 3.5.1.25 G Amidohydrolase family
DHMILLCL_01797 7.6e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DHMILLCL_01798 0.0 G Glycosyl hydrolase family 20, domain 2
DHMILLCL_01799 5.1e-165 2.7.1.2 GK ROK family
DHMILLCL_01800 1.1e-25 G ABC transporter permease
DHMILLCL_01801 5.5e-30 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DHMILLCL_01802 1.8e-83 K Cro/C1-type HTH DNA-binding domain
DHMILLCL_01803 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
DHMILLCL_01804 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01805 4.9e-268 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DHMILLCL_01806 5.5e-116 S Short repeat of unknown function (DUF308)
DHMILLCL_01807 2.7e-49 S Antitoxin component of a toxin-antitoxin (TA) module
DHMILLCL_01808 3.4e-55 DJ Addiction module toxin, RelE StbE family
DHMILLCL_01809 4.5e-13 S Psort location Extracellular, score 8.82
DHMILLCL_01810 1.7e-232 EGP Major facilitator Superfamily
DHMILLCL_01811 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DHMILLCL_01812 2e-269 KLT Domain of unknown function (DUF4032)
DHMILLCL_01813 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
DHMILLCL_01814 1.8e-130 K LytTr DNA-binding domain
DHMILLCL_01815 6.8e-233 T GHKL domain
DHMILLCL_01816 3.3e-210 clcA_2 P Voltage gated chloride channel
DHMILLCL_01817 2.1e-202 C Acetamidase/Formamidase family
DHMILLCL_01818 6.6e-85 K FCD
DHMILLCL_01819 3.3e-141 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
DHMILLCL_01820 3e-113 U Binding-protein-dependent transport system inner membrane component
DHMILLCL_01821 1.5e-150 ET Bacterial periplasmic substrate-binding proteins
DHMILLCL_01822 1.7e-213 E Aminotransferase class I and II
DHMILLCL_01823 1.5e-71 S GtrA-like protein
DHMILLCL_01824 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DHMILLCL_01825 4.9e-120 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
DHMILLCL_01826 2.4e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
DHMILLCL_01827 1.2e-112 vex2 V ABC transporter, ATP-binding protein
DHMILLCL_01828 2.7e-19 vex1 V Efflux ABC transporter, permease protein
DHMILLCL_01829 3.6e-43 vex1 V Efflux ABC transporter, permease protein
DHMILLCL_01830 1.8e-84 vex1 V Efflux ABC transporter, permease protein
DHMILLCL_01831 2.7e-158 vex3 V ABC transporter permease
DHMILLCL_01832 7.7e-50 vex3 V ABC transporter permease
DHMILLCL_01833 5.6e-14 lacS G Psort location CytoplasmicMembrane, score 10.00
DHMILLCL_01834 3.1e-41 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DHMILLCL_01835 8.8e-229 yhjX EGP Major facilitator Superfamily
DHMILLCL_01836 0.0 trxB1 1.8.1.9 C Thioredoxin domain
DHMILLCL_01837 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DHMILLCL_01838 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DHMILLCL_01839 1.3e-153 ypfH S Phospholipase/Carboxylesterase
DHMILLCL_01840 0.0 yjcE P Sodium/hydrogen exchanger family
DHMILLCL_01841 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DHMILLCL_01842 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DHMILLCL_01843 1.5e-230 nagC GK ROK family
DHMILLCL_01844 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
DHMILLCL_01845 6.6e-157 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01846 2.6e-155 G Binding-protein-dependent transport system inner membrane component
DHMILLCL_01847 3e-110 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)