ORF_ID e_value Gene_name EC_number CAZy COGs Description
HPNBHMFG_00001 1.1e-245 S zinc finger
HPNBHMFG_00002 7.5e-71 S Bacterial PH domain
HPNBHMFG_00003 1.5e-76
HPNBHMFG_00004 4.9e-201 V Domain of unknown function (DUF3427)
HPNBHMFG_00005 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
HPNBHMFG_00006 8.7e-187 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
HPNBHMFG_00007 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HPNBHMFG_00008 4.3e-233 aspB E Aminotransferase class-V
HPNBHMFG_00009 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HPNBHMFG_00010 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
HPNBHMFG_00011 3.8e-23
HPNBHMFG_00012 4.6e-43 V ATPases associated with a variety of cellular activities
HPNBHMFG_00013 7e-198 S Endonuclease/Exonuclease/phosphatase family
HPNBHMFG_00015 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPNBHMFG_00016 8.9e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HPNBHMFG_00017 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HPNBHMFG_00018 2.4e-138 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPNBHMFG_00019 1.5e-155 hgdC I BadF/BadG/BcrA/BcrD ATPase family
HPNBHMFG_00020 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HPNBHMFG_00021 1.4e-253 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HPNBHMFG_00022 8.5e-116 K Bacterial regulatory proteins, tetR family
HPNBHMFG_00023 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HPNBHMFG_00024 9.1e-110 K Bacterial regulatory proteins, tetR family
HPNBHMFG_00025 6e-236 G Transporter major facilitator family protein
HPNBHMFG_00026 9.5e-274 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HPNBHMFG_00027 2.7e-96 K transcriptional regulator
HPNBHMFG_00028 3.9e-221 blt G MFS/sugar transport protein
HPNBHMFG_00029 2.1e-301 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HPNBHMFG_00030 5.6e-12 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPNBHMFG_00031 4.2e-135 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPNBHMFG_00032 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
HPNBHMFG_00033 5.2e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
HPNBHMFG_00034 2.3e-113 K Bacterial regulatory proteins, tetR family
HPNBHMFG_00035 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HPNBHMFG_00036 8e-221 lmrB U Major Facilitator Superfamily
HPNBHMFG_00037 4.8e-14 K helix_turn_helix, mercury resistance
HPNBHMFG_00038 8.9e-118 K Periplasmic binding protein domain
HPNBHMFG_00039 1.3e-214 EGP Major facilitator Superfamily
HPNBHMFG_00040 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
HPNBHMFG_00041 1.1e-181 G Transporter major facilitator family protein
HPNBHMFG_00042 1.3e-189 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HPNBHMFG_00043 5.1e-107 K Bacterial regulatory proteins, tetR family
HPNBHMFG_00044 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HPNBHMFG_00045 5.1e-96 K MarR family
HPNBHMFG_00046 0.0 V ABC transporter, ATP-binding protein
HPNBHMFG_00047 0.0 V ABC transporter transmembrane region
HPNBHMFG_00048 2.8e-185 lacR K Transcriptional regulator, LacI family
HPNBHMFG_00049 1e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
HPNBHMFG_00050 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HPNBHMFG_00051 0.0 cas3 L DEAD-like helicases superfamily
HPNBHMFG_00052 1.2e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
HPNBHMFG_00053 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
HPNBHMFG_00054 1.3e-151 csd2 L CRISPR-associated protein Cas7
HPNBHMFG_00055 1.7e-130 cas4 3.1.12.1 L Domain of unknown function DUF83
HPNBHMFG_00056 6.5e-198 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPNBHMFG_00057 6.6e-47 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HPNBHMFG_00058 1.6e-125 S Phospholipase/Carboxylesterase
HPNBHMFG_00059 2.4e-239 patB 4.4.1.8 E Aminotransferase, class I II
HPNBHMFG_00060 5.1e-187 K LysR substrate binding domain protein
HPNBHMFG_00061 1e-156 S Patatin-like phospholipase
HPNBHMFG_00062 3.8e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
HPNBHMFG_00063 5e-301 E ABC transporter, substrate-binding protein, family 5
HPNBHMFG_00064 1e-20 S Patatin-like phospholipase
HPNBHMFG_00065 8.3e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HPNBHMFG_00066 3e-170 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HPNBHMFG_00067 1.8e-116 S Vitamin K epoxide reductase
HPNBHMFG_00068 3.8e-173 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HPNBHMFG_00069 3.6e-32 S Protein of unknown function (DUF3107)
HPNBHMFG_00070 1.1e-270 mphA S Aminoglycoside phosphotransferase
HPNBHMFG_00071 1.5e-280 uvrD2 3.6.4.12 L DNA helicase
HPNBHMFG_00072 1.7e-285 S Zincin-like metallopeptidase
HPNBHMFG_00073 5e-154 lon T Belongs to the peptidase S16 family
HPNBHMFG_00074 6.5e-75 S Protein of unknown function (DUF3052)
HPNBHMFG_00076 8.3e-237 2.7.11.1 NU Tfp pilus assembly protein FimV
HPNBHMFG_00077 5.5e-217 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HPNBHMFG_00078 4.3e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HPNBHMFG_00079 0.0 I acetylesterase activity
HPNBHMFG_00080 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
HPNBHMFG_00081 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HPNBHMFG_00082 1.4e-218 iunH1 3.2.2.1 F nucleoside hydrolase
HPNBHMFG_00083 1.6e-205 P NMT1/THI5 like
HPNBHMFG_00084 1.4e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00085 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HPNBHMFG_00086 2.8e-241 lacY P LacY proton/sugar symporter
HPNBHMFG_00087 3.7e-193 K helix_turn _helix lactose operon repressor
HPNBHMFG_00088 3e-60 S Thiamine-binding protein
HPNBHMFG_00089 1.2e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HPNBHMFG_00090 2e-132 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HPNBHMFG_00091 4.9e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HPNBHMFG_00092 0.0
HPNBHMFG_00093 0.0 pilT NU Type II/IV secretion system protein
HPNBHMFG_00094 0.0 pulE NU Type II/IV secretion system protein
HPNBHMFG_00095 4.9e-137 ppdC NU Prokaryotic N-terminal methylation motif
HPNBHMFG_00096 1.6e-104 S Prokaryotic N-terminal methylation motif
HPNBHMFG_00097 2.4e-46 pilA NU Prokaryotic N-terminal methylation motif
HPNBHMFG_00098 9.5e-231 pilC U Type II secretion system (T2SS), protein F
HPNBHMFG_00099 0.0
HPNBHMFG_00100 1.2e-149 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HPNBHMFG_00101 3e-190 pilM NU Type IV pilus assembly protein PilM;
HPNBHMFG_00102 8.1e-166 pilN NU PFAM Fimbrial assembly family protein
HPNBHMFG_00103 2.3e-105 S Pilus assembly protein, PilO
HPNBHMFG_00104 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HPNBHMFG_00105 2.2e-245 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HPNBHMFG_00106 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HPNBHMFG_00107 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HPNBHMFG_00108 1.2e-40 yggT S YGGT family
HPNBHMFG_00109 1.3e-30 3.1.21.3 V DivIVA protein
HPNBHMFG_00110 5.6e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HPNBHMFG_00111 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HPNBHMFG_00112 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HPNBHMFG_00113 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HPNBHMFG_00114 3.6e-224 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HPNBHMFG_00115 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HPNBHMFG_00116 4.4e-122
HPNBHMFG_00117 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HPNBHMFG_00118 1.2e-129 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HPNBHMFG_00119 1.2e-263 glnA2 6.3.1.2 E glutamine synthetase
HPNBHMFG_00120 5.6e-219 S Domain of unknown function (DUF5067)
HPNBHMFG_00121 5.3e-138 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HPNBHMFG_00122 3.2e-220 EGP Major facilitator Superfamily
HPNBHMFG_00123 1.2e-117 ytrE V ATPases associated with a variety of cellular activities
HPNBHMFG_00124 1.5e-89
HPNBHMFG_00125 1.4e-187 V N-Acetylmuramoyl-L-alanine amidase
HPNBHMFG_00126 1.9e-59
HPNBHMFG_00127 4.4e-112
HPNBHMFG_00128 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HPNBHMFG_00129 1.1e-112 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HPNBHMFG_00130 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HPNBHMFG_00131 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HPNBHMFG_00132 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HPNBHMFG_00133 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HPNBHMFG_00134 1e-53 M Lysin motif
HPNBHMFG_00135 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HPNBHMFG_00136 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HPNBHMFG_00137 0.0 L DNA helicase
HPNBHMFG_00138 7e-92 mraZ K Belongs to the MraZ family
HPNBHMFG_00139 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HPNBHMFG_00140 3.9e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HPNBHMFG_00141 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HPNBHMFG_00142 4.2e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPNBHMFG_00143 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HPNBHMFG_00144 1.5e-192 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HPNBHMFG_00145 2.5e-256 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HPNBHMFG_00146 1.4e-202 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HPNBHMFG_00147 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HPNBHMFG_00148 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
HPNBHMFG_00149 1.7e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
HPNBHMFG_00150 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HPNBHMFG_00151 1.6e-27
HPNBHMFG_00152 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
HPNBHMFG_00153 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
HPNBHMFG_00154 1.7e-218 GK ROK family
HPNBHMFG_00155 4.7e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HPNBHMFG_00156 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00157 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00158 0.0 P Belongs to the ABC transporter superfamily
HPNBHMFG_00159 9.9e-94 3.6.1.55 F NUDIX domain
HPNBHMFG_00160 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HPNBHMFG_00161 2.6e-273 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HPNBHMFG_00162 5e-187 V Acetyltransferase (GNAT) domain
HPNBHMFG_00163 7.1e-281 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HPNBHMFG_00164 7.4e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HPNBHMFG_00165 1.2e-36
HPNBHMFG_00166 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
HPNBHMFG_00167 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HPNBHMFG_00168 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HPNBHMFG_00169 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HPNBHMFG_00170 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HPNBHMFG_00171 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HPNBHMFG_00172 2.1e-25 rpmI J Ribosomal protein L35
HPNBHMFG_00173 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HPNBHMFG_00174 2e-177 xerD D recombinase XerD
HPNBHMFG_00175 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HPNBHMFG_00176 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
HPNBHMFG_00177 1.7e-249 naiP U Sugar (and other) transporter
HPNBHMFG_00178 0.0 typA T Elongation factor G C-terminus
HPNBHMFG_00179 4e-104
HPNBHMFG_00180 3.7e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HPNBHMFG_00181 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HPNBHMFG_00182 2.8e-34
HPNBHMFG_00183 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HPNBHMFG_00184 0.0 E ABC transporter, substrate-binding protein, family 5
HPNBHMFG_00185 0.0 E ABC transporter, substrate-binding protein, family 5
HPNBHMFG_00186 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00187 1.4e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
HPNBHMFG_00188 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
HPNBHMFG_00189 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HPNBHMFG_00190 1.7e-151 S Protein of unknown function (DUF3710)
HPNBHMFG_00191 2.4e-133 S Protein of unknown function (DUF3159)
HPNBHMFG_00192 2.8e-243 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HPNBHMFG_00193 2e-74
HPNBHMFG_00194 0.0 ctpE P E1-E2 ATPase
HPNBHMFG_00195 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HPNBHMFG_00196 2.9e-249 VP1224 V Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_00197 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HPNBHMFG_00198 3.2e-208 rhaR1 K helix_turn_helix, arabinose operon control protein
HPNBHMFG_00199 4.4e-228 V ABC-2 family transporter protein
HPNBHMFG_00200 3.8e-224 V ABC-2 family transporter protein
HPNBHMFG_00201 4.4e-191 V ATPases associated with a variety of cellular activities
HPNBHMFG_00202 1.1e-245 T Histidine kinase
HPNBHMFG_00203 9e-116 K helix_turn_helix, Lux Regulon
HPNBHMFG_00204 0.0 S Protein of unknown function DUF262
HPNBHMFG_00205 1.8e-127 K helix_turn_helix, Lux Regulon
HPNBHMFG_00206 9.1e-227 T Histidine kinase
HPNBHMFG_00207 1.6e-57 S Domain of unknown function (DUF5067)
HPNBHMFG_00208 1.7e-127 ybhL S Belongs to the BI1 family
HPNBHMFG_00209 8e-177 ydeD EG EamA-like transporter family
HPNBHMFG_00210 2.5e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HPNBHMFG_00211 8.7e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HPNBHMFG_00212 6e-191 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPNBHMFG_00213 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HPNBHMFG_00214 0.0 ftsK D FtsK SpoIIIE family protein
HPNBHMFG_00215 4.1e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPNBHMFG_00216 6.1e-97 cinA 3.5.1.42 S Belongs to the CinA family
HPNBHMFG_00217 1.6e-80 K Helix-turn-helix XRE-family like proteins
HPNBHMFG_00218 3e-46 S Protein of unknown function (DUF3046)
HPNBHMFG_00219 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HPNBHMFG_00220 6.6e-122 recX S Modulates RecA activity
HPNBHMFG_00221 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HPNBHMFG_00222 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HPNBHMFG_00223 6.5e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HPNBHMFG_00224 1.3e-97
HPNBHMFG_00225 1.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
HPNBHMFG_00226 0.0 pknL 2.7.11.1 KLT PASTA
HPNBHMFG_00227 1.4e-195 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HPNBHMFG_00228 1.1e-118
HPNBHMFG_00229 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HPNBHMFG_00230 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HPNBHMFG_00231 1.5e-222 G Major Facilitator Superfamily
HPNBHMFG_00232 3.3e-242 T PhoQ Sensor
HPNBHMFG_00233 2.4e-79 S Protein of unknown function (DUF2975)
HPNBHMFG_00234 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
HPNBHMFG_00235 0.0 lhr L DEAD DEAH box helicase
HPNBHMFG_00236 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HPNBHMFG_00237 1e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
HPNBHMFG_00238 7e-147 S Protein of unknown function (DUF3071)
HPNBHMFG_00239 1e-47 S Domain of unknown function (DUF4193)
HPNBHMFG_00240 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HPNBHMFG_00241 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HPNBHMFG_00242 3.5e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HPNBHMFG_00243 3.9e-233 dinF V MatE
HPNBHMFG_00244 0.0 S LPXTG-motif cell wall anchor domain protein
HPNBHMFG_00246 7.7e-27 L Helix-turn-helix domain
HPNBHMFG_00247 1.8e-101 V Abi-like protein
HPNBHMFG_00248 3.9e-16 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00249 1.1e-74
HPNBHMFG_00250 7.6e-110 metI P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00251 4.2e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPNBHMFG_00252 1.9e-147 metQ P NLPA lipoprotein
HPNBHMFG_00253 1.1e-155 S Sucrose-6F-phosphate phosphohydrolase
HPNBHMFG_00254 1.8e-225 S Peptidase dimerisation domain
HPNBHMFG_00255 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPNBHMFG_00256 4.5e-31
HPNBHMFG_00257 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HPNBHMFG_00258 2.8e-165 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HPNBHMFG_00259 9.9e-80 S Protein of unknown function (DUF3000)
HPNBHMFG_00260 9e-237 rnd 3.1.13.5 J 3'-5' exonuclease
HPNBHMFG_00261 1.2e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HPNBHMFG_00262 4.2e-130 yebE S DUF218 domain
HPNBHMFG_00263 8.4e-128 E Psort location Cytoplasmic, score 8.87
HPNBHMFG_00264 3.9e-159 O Thioredoxin
HPNBHMFG_00265 1.2e-158 msbA2 3.6.3.44 V ABC transporter transmembrane region
HPNBHMFG_00266 4.2e-138 3.6.3.44 V ABC transporter
HPNBHMFG_00267 0.0 KLT Lanthionine synthetase C-like protein
HPNBHMFG_00268 1.2e-120 K helix_turn_helix, Lux Regulon
HPNBHMFG_00269 4.8e-136 2.7.13.3 T Histidine kinase
HPNBHMFG_00271 1e-147 S phosphoesterase or phosphohydrolase
HPNBHMFG_00273 1.1e-89 insK L Integrase core domain
HPNBHMFG_00274 2.8e-50 insK L Integrase core domain
HPNBHMFG_00275 4.8e-54 mazG S MazG-like family
HPNBHMFG_00276 3e-269 L Uncharacterized conserved protein (DUF2075)
HPNBHMFG_00277 1.8e-27
HPNBHMFG_00278 8.1e-125 3.2.1.8 S alpha beta
HPNBHMFG_00279 1e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPNBHMFG_00280 2.9e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HPNBHMFG_00281 1.3e-113 kcsA U Ion channel
HPNBHMFG_00282 5.1e-39 pepC 3.4.22.40 E homocysteine catabolic process
HPNBHMFG_00283 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
HPNBHMFG_00284 2.3e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HPNBHMFG_00285 0.0 ecfA GP ABC transporter, ATP-binding protein
HPNBHMFG_00286 2.4e-47 yhbY J CRS1_YhbY
HPNBHMFG_00287 1.8e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HPNBHMFG_00288 2.2e-201 S Glycosyltransferase, group 2 family protein
HPNBHMFG_00289 2.7e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HPNBHMFG_00290 8.1e-221 E Aminotransferase class I and II
HPNBHMFG_00291 9.5e-144 bioM P ATPases associated with a variety of cellular activities
HPNBHMFG_00292 4.7e-307 2.8.2.22 S Arylsulfotransferase Ig-like domain
HPNBHMFG_00293 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HPNBHMFG_00294 0.0 S Tetratricopeptide repeat
HPNBHMFG_00295 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HPNBHMFG_00296 8.2e-213 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HPNBHMFG_00297 4.9e-84 ykoE S ABC-type cobalt transport system, permease component
HPNBHMFG_00298 2.3e-268 ykoD P ATPases associated with a variety of cellular activities
HPNBHMFG_00299 3.1e-145 cbiQ P Cobalt transport protein
HPNBHMFG_00300 2.3e-251 argE E Peptidase dimerisation domain
HPNBHMFG_00301 3.6e-93 S Protein of unknown function (DUF3043)
HPNBHMFG_00302 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HPNBHMFG_00303 8.6e-142 S Domain of unknown function (DUF4191)
HPNBHMFG_00304 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
HPNBHMFG_00305 4e-42 V DNA modification
HPNBHMFG_00306 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
HPNBHMFG_00307 1.5e-17 L HNH endonuclease
HPNBHMFG_00309 2.9e-17
HPNBHMFG_00310 2.7e-94 yvdD 3.2.2.10 S Possible lysine decarboxylase
HPNBHMFG_00312 5.9e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HPNBHMFG_00313 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HPNBHMFG_00314 4.9e-99
HPNBHMFG_00315 4.5e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HPNBHMFG_00316 6.7e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HPNBHMFG_00317 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HPNBHMFG_00318 2.7e-241 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HPNBHMFG_00319 4.6e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HPNBHMFG_00320 2.3e-82 argR K Regulates arginine biosynthesis genes
HPNBHMFG_00321 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HPNBHMFG_00322 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
HPNBHMFG_00323 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HPNBHMFG_00324 1.5e-136 S Putative ABC-transporter type IV
HPNBHMFG_00325 0.0 S Protein of unknown function (DUF975)
HPNBHMFG_00326 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HPNBHMFG_00327 1.5e-149 L Tetratricopeptide repeat
HPNBHMFG_00328 1.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HPNBHMFG_00329 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HPNBHMFG_00330 3e-116 trkA P TrkA-N domain
HPNBHMFG_00331 2.2e-263 trkB P Cation transport protein
HPNBHMFG_00332 2.9e-176 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HPNBHMFG_00333 4.8e-262 recN L May be involved in recombinational repair of damaged DNA
HPNBHMFG_00334 4.4e-123 S Haloacid dehalogenase-like hydrolase
HPNBHMFG_00335 6.1e-118 S ABC-2 family transporter protein
HPNBHMFG_00336 3e-173 V ATPases associated with a variety of cellular activities
HPNBHMFG_00337 6.4e-58 K helix_turn_helix gluconate operon transcriptional repressor
HPNBHMFG_00338 4.3e-23 C Acetamidase/Formamidase family
HPNBHMFG_00339 2.7e-44 L transposition
HPNBHMFG_00340 0.0 S Histidine phosphatase superfamily (branch 2)
HPNBHMFG_00341 1.7e-94 S Pyridoxamine 5'-phosphate oxidase
HPNBHMFG_00342 2.6e-22 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00343 6.4e-96 bcp 1.11.1.15 O Redoxin
HPNBHMFG_00345 7.4e-77 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPNBHMFG_00346 5.3e-167 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HPNBHMFG_00347 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
HPNBHMFG_00348 2e-142
HPNBHMFG_00349 7.4e-174 G Fic/DOC family
HPNBHMFG_00350 4.7e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
HPNBHMFG_00351 5.1e-232 EGP Major facilitator Superfamily
HPNBHMFG_00352 1.5e-283 thrC 4.2.3.1 E Threonine synthase N terminus
HPNBHMFG_00353 9.3e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HPNBHMFG_00354 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HPNBHMFG_00355 3.2e-101
HPNBHMFG_00356 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HPNBHMFG_00357 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPNBHMFG_00359 1.8e-121
HPNBHMFG_00360 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HPNBHMFG_00361 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPNBHMFG_00362 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HPNBHMFG_00363 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HPNBHMFG_00365 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HPNBHMFG_00366 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HPNBHMFG_00367 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HPNBHMFG_00368 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HPNBHMFG_00369 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HPNBHMFG_00370 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HPNBHMFG_00371 3.3e-294 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HPNBHMFG_00372 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HPNBHMFG_00373 1.3e-159 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HPNBHMFG_00374 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HPNBHMFG_00375 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HPNBHMFG_00376 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HPNBHMFG_00377 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HPNBHMFG_00378 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HPNBHMFG_00379 9.9e-172 S Bacterial protein of unknown function (DUF881)
HPNBHMFG_00380 4.2e-45 sbp S Protein of unknown function (DUF1290)
HPNBHMFG_00381 2e-141 S Bacterial protein of unknown function (DUF881)
HPNBHMFG_00382 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HPNBHMFG_00383 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
HPNBHMFG_00384 5.2e-128 yebC K transcriptional regulatory protein
HPNBHMFG_00385 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HPNBHMFG_00386 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HPNBHMFG_00387 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HPNBHMFG_00388 1e-58 yajC U Preprotein translocase subunit
HPNBHMFG_00389 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HPNBHMFG_00390 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HPNBHMFG_00391 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HPNBHMFG_00392 1.8e-246
HPNBHMFG_00393 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HPNBHMFG_00394 8.2e-34
HPNBHMFG_00395 4e-154 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HPNBHMFG_00396 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HPNBHMFG_00397 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HPNBHMFG_00398 1.1e-69
HPNBHMFG_00400 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HPNBHMFG_00401 0.0 pafB K WYL domain
HPNBHMFG_00402 2.1e-54
HPNBHMFG_00403 0.0 helY L DEAD DEAH box helicase
HPNBHMFG_00404 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HPNBHMFG_00405 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
HPNBHMFG_00406 4.6e-61
HPNBHMFG_00407 9.7e-112 K helix_turn_helix, mercury resistance
HPNBHMFG_00408 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
HPNBHMFG_00409 5.4e-36
HPNBHMFG_00410 2.5e-08
HPNBHMFG_00417 1.4e-155 S PAC2 family
HPNBHMFG_00418 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HPNBHMFG_00419 5.1e-158 G Fructosamine kinase
HPNBHMFG_00420 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HPNBHMFG_00421 1e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HPNBHMFG_00422 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HPNBHMFG_00423 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HPNBHMFG_00424 1.4e-40 nadR H ATPase kinase involved in NAD metabolism
HPNBHMFG_00425 2.5e-49 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
HPNBHMFG_00426 1.6e-111 pnuC H Nicotinamide mononucleotide transporter
HPNBHMFG_00427 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
HPNBHMFG_00428 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HPNBHMFG_00429 1.3e-162 S Sucrose-6F-phosphate phosphohydrolase
HPNBHMFG_00430 2.4e-32 secG U Preprotein translocase SecG subunit
HPNBHMFG_00431 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HPNBHMFG_00432 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HPNBHMFG_00433 1.3e-171 whiA K May be required for sporulation
HPNBHMFG_00434 1.1e-170 rapZ S Displays ATPase and GTPase activities
HPNBHMFG_00435 6e-182 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HPNBHMFG_00436 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HPNBHMFG_00437 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HPNBHMFG_00438 2.4e-220 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00439 0.0 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00440 9.5e-141 S Domain of unknown function (DUF4194)
HPNBHMFG_00441 7.6e-273 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00442 2e-13
HPNBHMFG_00444 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HPNBHMFG_00445 2.3e-110 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
HPNBHMFG_00446 1.9e-300 ybiT S ABC transporter
HPNBHMFG_00447 1e-173 S IMP dehydrogenase activity
HPNBHMFG_00448 6.1e-279 pepC 3.4.22.40 E Peptidase C1-like family
HPNBHMFG_00449 2.9e-142 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00450 4.1e-57
HPNBHMFG_00451 1.9e-26
HPNBHMFG_00452 4.2e-108
HPNBHMFG_00455 1e-182 cat P Cation efflux family
HPNBHMFG_00456 1.8e-75 S Psort location CytoplasmicMembrane, score
HPNBHMFG_00457 6e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
HPNBHMFG_00458 2.6e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
HPNBHMFG_00459 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HPNBHMFG_00460 6.7e-72 K MerR family regulatory protein
HPNBHMFG_00461 7.2e-116 ykoE S ABC-type cobalt transport system, permease component
HPNBHMFG_00462 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HPNBHMFG_00463 2.6e-119 yoaP E YoaP-like
HPNBHMFG_00465 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HPNBHMFG_00466 7.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HPNBHMFG_00467 6.4e-148 yeaZ 2.3.1.234 O Glycoprotease family
HPNBHMFG_00468 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HPNBHMFG_00469 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
HPNBHMFG_00470 0.0 comE S Competence protein
HPNBHMFG_00471 2.2e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HPNBHMFG_00472 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPNBHMFG_00473 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
HPNBHMFG_00474 5.7e-172 corA P CorA-like Mg2+ transporter protein
HPNBHMFG_00475 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPNBHMFG_00476 5.2e-65 3.4.22.70 M Sortase family
HPNBHMFG_00477 5.6e-83 3.4.22.70 M Sortase family
HPNBHMFG_00478 4.6e-302 M domain protein
HPNBHMFG_00479 2.7e-70 pdxH S Pfam:Pyridox_oxidase
HPNBHMFG_00480 1.3e-232 XK27_00240 K Fic/DOC family
HPNBHMFG_00482 6.2e-117
HPNBHMFG_00483 4.3e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HPNBHMFG_00484 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HPNBHMFG_00485 5.8e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HPNBHMFG_00486 4.5e-26 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPNBHMFG_00487 1.3e-15 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HPNBHMFG_00488 3e-107 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HPNBHMFG_00489 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
HPNBHMFG_00490 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HPNBHMFG_00491 1.1e-268 G ABC transporter substrate-binding protein
HPNBHMFG_00492 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
HPNBHMFG_00493 3.3e-96 M Peptidase family M23
HPNBHMFG_00494 2.3e-60
HPNBHMFG_00497 5e-125 XK27_06785 V ABC transporter
HPNBHMFG_00498 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HPNBHMFG_00499 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPNBHMFG_00500 2.3e-139 S SdpI/YhfL protein family
HPNBHMFG_00501 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
HPNBHMFG_00502 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HPNBHMFG_00503 2.8e-218 yxjG_1 E Psort location Cytoplasmic, score 8.87
HPNBHMFG_00504 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HPNBHMFG_00505 8.8e-109 J Acetyltransferase (GNAT) domain
HPNBHMFG_00506 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HPNBHMFG_00507 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HPNBHMFG_00508 2.7e-123 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPNBHMFG_00509 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HPNBHMFG_00510 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HPNBHMFG_00511 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HPNBHMFG_00512 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HPNBHMFG_00513 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HPNBHMFG_00514 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HPNBHMFG_00515 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HPNBHMFG_00516 6.8e-19
HPNBHMFG_00517 6.4e-184 gguB U Branched-chain amino acid transport system / permease component
HPNBHMFG_00518 3e-271 araG 3.6.3.17 G ATPases associated with a variety of cellular activities
HPNBHMFG_00519 5e-186 G Periplasmic binding protein domain
HPNBHMFG_00520 5e-178 GK ROK family
HPNBHMFG_00521 7.1e-126 xylG 3.6.3.17 G ATPases associated with a variety of cellular activities
HPNBHMFG_00522 9.5e-29
HPNBHMFG_00523 2.9e-43 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HPNBHMFG_00524 7.3e-155 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HPNBHMFG_00525 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HPNBHMFG_00526 1.5e-28 S Putative phage holin Dp-1
HPNBHMFG_00527 1.9e-199 M Glycosyl hydrolases family 25
HPNBHMFG_00530 1.8e-40 MU outer membrane autotransporter barrel domain protein
HPNBHMFG_00531 3.7e-19
HPNBHMFG_00532 8.1e-93 L DNA integration
HPNBHMFG_00533 1.1e-45
HPNBHMFG_00535 2.1e-85
HPNBHMFG_00537 9.9e-301 S Psort location Cytoplasmic, score
HPNBHMFG_00538 1.1e-142
HPNBHMFG_00539 1.5e-196 S phage tail tape measure protein
HPNBHMFG_00541 8.6e-63
HPNBHMFG_00542 1.1e-110
HPNBHMFG_00543 1.7e-61
HPNBHMFG_00544 4.7e-35
HPNBHMFG_00545 1e-43
HPNBHMFG_00546 2.5e-65 S Phage protein Gp19/Gp15/Gp42
HPNBHMFG_00548 4.2e-153 V Phage capsid family
HPNBHMFG_00549 3.1e-71
HPNBHMFG_00551 3.3e-114
HPNBHMFG_00552 6.1e-245 S Phage portal protein, SPP1 Gp6-like
HPNBHMFG_00553 9.9e-269 S Terminase
HPNBHMFG_00554 1.8e-58
HPNBHMFG_00555 1.3e-51 V HNH nucleases
HPNBHMFG_00556 1.6e-165 J tRNA 5'-leader removal
HPNBHMFG_00557 2.2e-16
HPNBHMFG_00560 1.2e-10
HPNBHMFG_00563 1.2e-103 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPNBHMFG_00564 1.1e-76 V HNH endonuclease
HPNBHMFG_00565 4.7e-25
HPNBHMFG_00566 4.8e-136 K Transcriptional regulator
HPNBHMFG_00568 4.4e-63 ssb1 L Single-strand binding protein family
HPNBHMFG_00573 8.5e-37
HPNBHMFG_00575 2.4e-107 K BRO family, N-terminal domain
HPNBHMFG_00580 1.1e-10
HPNBHMFG_00581 2.3e-103 dinD S SOS response
HPNBHMFG_00582 1.5e-30
HPNBHMFG_00583 1.9e-86
HPNBHMFG_00584 3.7e-54 S PFAM Uncharacterised protein family UPF0150
HPNBHMFG_00585 1e-34 N HicA toxin of bacterial toxin-antitoxin,
HPNBHMFG_00586 5.2e-20 S Predicted membrane protein (DUF2335)
HPNBHMFG_00587 6.3e-25 S Predicted membrane protein (DUF2335)
HPNBHMFG_00588 2.4e-239 int L Phage integrase, N-terminal SAM-like domain
HPNBHMFG_00589 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
HPNBHMFG_00590 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HPNBHMFG_00591 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HPNBHMFG_00592 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HPNBHMFG_00593 2e-74
HPNBHMFG_00594 3.2e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HPNBHMFG_00595 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HPNBHMFG_00596 2.5e-234 F Psort location CytoplasmicMembrane, score 10.00
HPNBHMFG_00597 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
HPNBHMFG_00598 7.6e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
HPNBHMFG_00599 5e-145 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HPNBHMFG_00600 3e-234 hemN H Involved in the biosynthesis of porphyrin-containing compound
HPNBHMFG_00601 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HPNBHMFG_00602 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
HPNBHMFG_00603 1.1e-133 S UPF0126 domain
HPNBHMFG_00604 7.3e-227 ilvE 2.6.1.42 E Amino-transferase class IV
HPNBHMFG_00606 1.2e-73 K Acetyltransferase (GNAT) domain
HPNBHMFG_00607 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPNBHMFG_00608 1.4e-92 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPNBHMFG_00609 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HPNBHMFG_00610 3.8e-195 S alpha beta
HPNBHMFG_00611 6.5e-25 yhjX EGP Major facilitator Superfamily
HPNBHMFG_00612 2.6e-30 EGP Major facilitator Superfamily
HPNBHMFG_00613 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HPNBHMFG_00614 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPNBHMFG_00616 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HPNBHMFG_00617 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
HPNBHMFG_00618 1.1e-39 nrdH O Glutaredoxin
HPNBHMFG_00619 1.6e-120 K Bacterial regulatory proteins, tetR family
HPNBHMFG_00620 1.5e-223 G Transmembrane secretion effector
HPNBHMFG_00622 4.2e-269 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_00623 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HPNBHMFG_00624 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HPNBHMFG_00625 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HPNBHMFG_00626 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HPNBHMFG_00627 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HPNBHMFG_00628 4.1e-251 corC S CBS domain
HPNBHMFG_00629 2.1e-102 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HPNBHMFG_00630 5.9e-208 phoH T PhoH-like protein
HPNBHMFG_00631 6.9e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HPNBHMFG_00632 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HPNBHMFG_00634 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
HPNBHMFG_00635 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HPNBHMFG_00636 6.1e-108 yitW S Iron-sulfur cluster assembly protein
HPNBHMFG_00637 2.6e-97 iscU C SUF system FeS assembly protein, NifU family
HPNBHMFG_00638 1.2e-238 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HPNBHMFG_00639 1e-142 sufC O FeS assembly ATPase SufC
HPNBHMFG_00640 6.1e-235 sufD O FeS assembly protein SufD
HPNBHMFG_00641 1.6e-290 sufB O FeS assembly protein SufB
HPNBHMFG_00642 0.0 S L,D-transpeptidase catalytic domain
HPNBHMFG_00643 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HPNBHMFG_00644 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
HPNBHMFG_00645 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HPNBHMFG_00646 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HPNBHMFG_00647 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HPNBHMFG_00648 9.3e-57 3.4.23.43 S Type IV leader peptidase family
HPNBHMFG_00649 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HPNBHMFG_00650 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HPNBHMFG_00651 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HPNBHMFG_00652 2.5e-36
HPNBHMFG_00653 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HPNBHMFG_00654 5.6e-129 pgm3 G Phosphoglycerate mutase family
HPNBHMFG_00655 1.2e-38 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HPNBHMFG_00656 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HPNBHMFG_00657 1.9e-150 lolD V ABC transporter
HPNBHMFG_00658 4.8e-216 V FtsX-like permease family
HPNBHMFG_00659 1.7e-61 S Domain of unknown function (DUF4418)
HPNBHMFG_00660 0.0 pcrA 3.6.4.12 L DNA helicase
HPNBHMFG_00661 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HPNBHMFG_00662 2.8e-244 pbuX F Permease family
HPNBHMFG_00663 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_00664 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HPNBHMFG_00665 6e-302 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HPNBHMFG_00666 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HPNBHMFG_00667 8.7e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HPNBHMFG_00668 8.1e-66 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
HPNBHMFG_00669 2.8e-249 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HPNBHMFG_00671 1.4e-212 ykiI
HPNBHMFG_00672 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HPNBHMFG_00673 4.6e-120 3.6.1.13 L NUDIX domain
HPNBHMFG_00674 3.5e-171 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HPNBHMFG_00675 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HPNBHMFG_00676 9.4e-101 pdtaR T Response regulator receiver domain protein
HPNBHMFG_00677 2.1e-165 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
HPNBHMFG_00678 1.6e-102 hsdM 2.1.1.72 V HsdM N-terminal domain
HPNBHMFG_00679 9.8e-28 L Protein of unknown function (DUF1524)
HPNBHMFG_00680 4.2e-21 K Cro/C1-type HTH DNA-binding domain
HPNBHMFG_00681 1.8e-128 S Uncharacterised protein conserved in bacteria (DUF2326)
HPNBHMFG_00682 3.8e-16
HPNBHMFG_00683 1.7e-66 S Psort location Cytoplasmic, score
HPNBHMFG_00685 2.3e-17 K Psort location Cytoplasmic, score
HPNBHMFG_00687 2.8e-146 2.7.7.7 L Transposase, Mutator family
HPNBHMFG_00688 5.3e-152 L Phage integrase family
HPNBHMFG_00689 3.9e-16
HPNBHMFG_00690 3.4e-43 K Helix-turn-helix domain protein
HPNBHMFG_00691 2.7e-13 K Helix-turn-helix domain protein
HPNBHMFG_00692 6.8e-36 rplV S ASCH
HPNBHMFG_00693 2.2e-32 topB 5.99.1.2 L DNA topoisomerase
HPNBHMFG_00694 6.2e-122 L Integrase core domain
HPNBHMFG_00695 1.3e-42 L Psort location Cytoplasmic, score 8.87
HPNBHMFG_00696 2.6e-111 sprF 4.6.1.1 M Cell surface antigen C-terminus
HPNBHMFG_00698 1.3e-64 dam2 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
HPNBHMFG_00699 5e-68
HPNBHMFG_00701 8.5e-24
HPNBHMFG_00702 1.1e-97
HPNBHMFG_00703 1.5e-45 S PrgI family protein
HPNBHMFG_00704 0.0 trsE U type IV secretory pathway VirB4
HPNBHMFG_00705 3.3e-155 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
HPNBHMFG_00706 2.8e-22 V Type II restriction enzyme, methylase subunits
HPNBHMFG_00707 1.8e-75 G ABC transporter permease
HPNBHMFG_00708 3.1e-28 G ABC transporter permease
HPNBHMFG_00709 3.3e-147 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00710 1.6e-253 EGP Transmembrane secretion effector
HPNBHMFG_00711 1.4e-189 K Periplasmic binding protein domain
HPNBHMFG_00712 5.3e-229 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
HPNBHMFG_00713 1.2e-143 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HPNBHMFG_00714 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HPNBHMFG_00715 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HPNBHMFG_00716 2.2e-142 yecS E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00717 6.4e-128 pknD ET ABC transporter, substrate-binding protein, family 3
HPNBHMFG_00718 8.9e-32 pknD ET ABC transporter, substrate-binding protein, family 3
HPNBHMFG_00719 1.1e-156 pknD ET ABC transporter, substrate-binding protein, family 3
HPNBHMFG_00720 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HPNBHMFG_00721 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
HPNBHMFG_00722 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HPNBHMFG_00723 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
HPNBHMFG_00724 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HPNBHMFG_00725 3.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HPNBHMFG_00726 3.7e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HPNBHMFG_00727 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HPNBHMFG_00728 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
HPNBHMFG_00729 0.0 pepO 3.4.24.71 O Peptidase family M13
HPNBHMFG_00730 6.8e-98 L Single-strand binding protein family
HPNBHMFG_00731 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HPNBHMFG_00732 5.1e-270 recD2 3.6.4.12 L PIF1-like helicase
HPNBHMFG_00733 2.5e-161 supH S Sucrose-6F-phosphate phosphohydrolase
HPNBHMFG_00734 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPNBHMFG_00735 2.7e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HPNBHMFG_00736 4.5e-195 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HPNBHMFG_00737 7.6e-115 ywlC 2.7.7.87 J Belongs to the SUA5 family
HPNBHMFG_00738 1.9e-124 livF E ATPases associated with a variety of cellular activities
HPNBHMFG_00739 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
HPNBHMFG_00740 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
HPNBHMFG_00741 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
HPNBHMFG_00742 7.8e-219 livK E Receptor family ligand binding region
HPNBHMFG_00743 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HPNBHMFG_00744 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HPNBHMFG_00745 1.5e-35 rpmE J Binds the 23S rRNA
HPNBHMFG_00747 6.8e-226 xylR GK ROK family
HPNBHMFG_00748 3.8e-287 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HPNBHMFG_00749 2.1e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HPNBHMFG_00750 9.7e-09 CE10 I Belongs to the type-B carboxylesterase lipase family
HPNBHMFG_00751 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HPNBHMFG_00752 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HPNBHMFG_00753 2.3e-159 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00754 3.4e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00755 2.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HPNBHMFG_00756 8.8e-187 K Bacterial regulatory proteins, lacI family
HPNBHMFG_00757 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
HPNBHMFG_00758 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HPNBHMFG_00759 6.3e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HPNBHMFG_00760 4.9e-295 S Amidohydrolase family
HPNBHMFG_00762 1.1e-162 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
HPNBHMFG_00763 1.7e-67 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HPNBHMFG_00764 4.2e-180 V Beta-lactamase
HPNBHMFG_00765 0.0 yjjK S ATP-binding cassette protein, ChvD family
HPNBHMFG_00766 8.5e-165 tesB I Thioesterase-like superfamily
HPNBHMFG_00767 6.2e-94 S Protein of unknown function (DUF3180)
HPNBHMFG_00768 1.1e-273 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HPNBHMFG_00769 4.9e-154 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HPNBHMFG_00770 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
HPNBHMFG_00771 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HPNBHMFG_00772 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HPNBHMFG_00773 1.1e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HPNBHMFG_00774 7.9e-234 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HPNBHMFG_00775 6.3e-232 epsG M Glycosyl transferase family 21
HPNBHMFG_00776 1.3e-237 S AI-2E family transporter
HPNBHMFG_00777 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
HPNBHMFG_00778 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
HPNBHMFG_00779 0.0 yliE T Putative diguanylate phosphodiesterase
HPNBHMFG_00780 2.2e-111 S Domain of unknown function (DUF4956)
HPNBHMFG_00781 6.9e-158 P VTC domain
HPNBHMFG_00782 6.5e-310 cotH M CotH kinase protein
HPNBHMFG_00783 2.1e-285 pelG S Putative exopolysaccharide Exporter (EPS-E)
HPNBHMFG_00784 1.9e-166 pelF GT4 M Domain of unknown function (DUF3492)
HPNBHMFG_00785 1.9e-104 pelF GT4 M Domain of unknown function (DUF3492)
HPNBHMFG_00786 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
HPNBHMFG_00787 3e-154
HPNBHMFG_00788 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
HPNBHMFG_00792 2.7e-163 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HPNBHMFG_00793 7.6e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HPNBHMFG_00795 3.6e-85 ptpA 3.1.3.48 T low molecular weight
HPNBHMFG_00796 1.9e-129 folA 1.5.1.3 H dihydrofolate reductase
HPNBHMFG_00797 1.9e-180 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HPNBHMFG_00798 3.8e-72 attW O OsmC-like protein
HPNBHMFG_00799 1.9e-189 T Universal stress protein family
HPNBHMFG_00800 1.3e-79 M NlpC/P60 family
HPNBHMFG_00801 1.6e-166 usp 3.5.1.28 CBM50 S CHAP domain
HPNBHMFG_00802 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HPNBHMFG_00803 6.2e-41
HPNBHMFG_00804 2.3e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPNBHMFG_00805 2.5e-105 phoU P Plays a role in the regulation of phosphate uptake
HPNBHMFG_00806 0.0 4.2.1.53 S MCRA family
HPNBHMFG_00807 3e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HPNBHMFG_00808 2.6e-200 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HPNBHMFG_00809 4.1e-99 S Serine aminopeptidase, S33
HPNBHMFG_00810 7.4e-250 G Psort location CytoplasmicMembrane, score 10.00
HPNBHMFG_00811 9.3e-192 K helix_turn _helix lactose operon repressor
HPNBHMFG_00812 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HPNBHMFG_00814 1.2e-211 araJ EGP Major facilitator Superfamily
HPNBHMFG_00815 0.0 S Domain of unknown function (DUF4037)
HPNBHMFG_00816 6.7e-116 S Protein of unknown function (DUF4125)
HPNBHMFG_00817 2.8e-89
HPNBHMFG_00818 7.5e-147 pspC KT PspC domain
HPNBHMFG_00819 1.9e-268 tcsS3 KT PspC domain
HPNBHMFG_00820 5.6e-121 degU K helix_turn_helix, Lux Regulon
HPNBHMFG_00821 3.7e-102 Q Isochorismatase family
HPNBHMFG_00822 2e-269 U Permease for cytosine/purines, uracil, thiamine, allantoin
HPNBHMFG_00823 8.3e-190 yegV G pfkB family carbohydrate kinase
HPNBHMFG_00824 6.7e-187 yegU O ADP-ribosylglycohydrolase
HPNBHMFG_00826 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HPNBHMFG_00827 9.8e-200 I Diacylglycerol kinase catalytic domain
HPNBHMFG_00828 4e-156 arbG K CAT RNA binding domain
HPNBHMFG_00829 0.0 crr G pts system, glucose-specific IIABC component
HPNBHMFG_00830 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HPNBHMFG_00831 8e-151 T LytTr DNA-binding domain
HPNBHMFG_00832 5.7e-250 T GHKL domain
HPNBHMFG_00833 7.3e-212 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPNBHMFG_00834 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HPNBHMFG_00836 2.8e-106
HPNBHMFG_00837 4.1e-251 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HPNBHMFG_00838 1.8e-218 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HPNBHMFG_00839 5.1e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HPNBHMFG_00840 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HPNBHMFG_00841 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HPNBHMFG_00842 6.1e-191 nusA K Participates in both transcription termination and antitermination
HPNBHMFG_00843 4.7e-104
HPNBHMFG_00845 2e-169 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HPNBHMFG_00846 7.8e-64 rplQ J Ribosomal protein L17
HPNBHMFG_00847 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPNBHMFG_00848 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HPNBHMFG_00849 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HPNBHMFG_00850 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HPNBHMFG_00851 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HPNBHMFG_00852 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HPNBHMFG_00853 9.9e-239 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HPNBHMFG_00854 9.8e-74 rplO J binds to the 23S rRNA
HPNBHMFG_00855 3.4e-25 rpmD J Ribosomal protein L30p/L7e
HPNBHMFG_00856 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HPNBHMFG_00857 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HPNBHMFG_00858 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HPNBHMFG_00859 4.6e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HPNBHMFG_00860 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HPNBHMFG_00861 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HPNBHMFG_00862 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HPNBHMFG_00863 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HPNBHMFG_00864 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HPNBHMFG_00865 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
HPNBHMFG_00866 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HPNBHMFG_00867 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HPNBHMFG_00868 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HPNBHMFG_00869 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HPNBHMFG_00870 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HPNBHMFG_00871 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HPNBHMFG_00872 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
HPNBHMFG_00873 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HPNBHMFG_00874 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HPNBHMFG_00875 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HPNBHMFG_00876 4.7e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
HPNBHMFG_00877 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
HPNBHMFG_00878 4.2e-239 EGP Major facilitator Superfamily
HPNBHMFG_00879 1.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HPNBHMFG_00880 3.2e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HPNBHMFG_00881 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HPNBHMFG_00882 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
HPNBHMFG_00883 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HPNBHMFG_00884 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HPNBHMFG_00885 3.1e-122
HPNBHMFG_00886 6.2e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HPNBHMFG_00887 2.7e-185 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HPNBHMFG_00888 7.2e-253 M Bacterial capsule synthesis protein PGA_cap
HPNBHMFG_00889 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HPNBHMFG_00891 3.6e-295 CE10 I Belongs to the type-B carboxylesterase lipase family
HPNBHMFG_00892 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HPNBHMFG_00893 2e-232 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
HPNBHMFG_00894 0.0 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_00895 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HPNBHMFG_00896 7.4e-152 dppF E ABC transporter
HPNBHMFG_00897 6.7e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
HPNBHMFG_00898 3.9e-141 EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00899 2.4e-181 EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_00900 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
HPNBHMFG_00902 4.9e-210 dapC E Aminotransferase class I and II
HPNBHMFG_00903 8.3e-59 fdxA C 4Fe-4S binding domain
HPNBHMFG_00904 9.6e-267 E aromatic amino acid transport protein AroP K03293
HPNBHMFG_00905 3.4e-206 murB 1.3.1.98 M Cell wall formation
HPNBHMFG_00906 5.5e-25 rpmG J Ribosomal protein L33
HPNBHMFG_00910 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HPNBHMFG_00911 1.4e-146
HPNBHMFG_00912 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
HPNBHMFG_00913 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HPNBHMFG_00914 6.1e-30 fmdB S Putative regulatory protein
HPNBHMFG_00915 1.9e-92 flgA NO SAF
HPNBHMFG_00916 7e-35
HPNBHMFG_00917 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HPNBHMFG_00918 2.1e-175 T Forkhead associated domain
HPNBHMFG_00919 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HPNBHMFG_00920 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HPNBHMFG_00921 1.3e-246 pbuO S Permease family
HPNBHMFG_00922 9.5e-145 P Zinc-uptake complex component A periplasmic
HPNBHMFG_00923 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HPNBHMFG_00924 5.2e-168 pstA P Phosphate transport system permease
HPNBHMFG_00925 1.3e-163 pstC P probably responsible for the translocation of the substrate across the membrane
HPNBHMFG_00926 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HPNBHMFG_00927 3.4e-129 KT Transcriptional regulatory protein, C terminal
HPNBHMFG_00928 6.3e-220 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HPNBHMFG_00929 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HPNBHMFG_00930 4.4e-222 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPNBHMFG_00931 3.3e-211 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HPNBHMFG_00932 6.6e-267 pepC 3.4.22.40 E Peptidase C1-like family
HPNBHMFG_00933 1.3e-58 D nuclear chromosome segregation
HPNBHMFG_00934 5.8e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HPNBHMFG_00935 2.4e-150 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HPNBHMFG_00936 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HPNBHMFG_00937 7e-297 yegQ O Peptidase family U32 C-terminal domain
HPNBHMFG_00938 9.7e-171 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HPNBHMFG_00939 0.0 S Predicted membrane protein (DUF2207)
HPNBHMFG_00940 8.5e-91 lemA S LemA family
HPNBHMFG_00941 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HPNBHMFG_00942 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HPNBHMFG_00943 2.4e-116
HPNBHMFG_00945 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
HPNBHMFG_00946 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HPNBHMFG_00948 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HPNBHMFG_00949 0.0 pccB I Carboxyl transferase domain
HPNBHMFG_00950 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HPNBHMFG_00951 2.1e-79 bioY S BioY family
HPNBHMFG_00952 1.3e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HPNBHMFG_00953 0.0
HPNBHMFG_00954 5.9e-143 QT PucR C-terminal helix-turn-helix domain
HPNBHMFG_00955 8.8e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HPNBHMFG_00956 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HPNBHMFG_00957 2.9e-129 nusG K Participates in transcription elongation, termination and antitermination
HPNBHMFG_00958 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HPNBHMFG_00960 3.3e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HPNBHMFG_00961 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HPNBHMFG_00962 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HPNBHMFG_00963 2.6e-39 rpmA J Ribosomal L27 protein
HPNBHMFG_00964 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HPNBHMFG_00965 2.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
HPNBHMFG_00966 4.4e-230 dapE 3.5.1.18 E Peptidase dimerisation domain
HPNBHMFG_00967 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
HPNBHMFG_00968 2.5e-270 V Efflux ABC transporter, permease protein
HPNBHMFG_00969 1.9e-127 V ATPases associated with a variety of cellular activities
HPNBHMFG_00970 8e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HPNBHMFG_00971 2.6e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HPNBHMFG_00972 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HPNBHMFG_00973 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HPNBHMFG_00974 5.4e-181 S Auxin Efflux Carrier
HPNBHMFG_00977 7.7e-220 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HPNBHMFG_00978 2.6e-241 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HPNBHMFG_00979 1.7e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HPNBHMFG_00980 1.9e-138 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HPNBHMFG_00981 4e-119 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HPNBHMFG_00982 9.2e-77 soxR K MerR, DNA binding
HPNBHMFG_00983 1.7e-195 yghZ C Aldo/keto reductase family
HPNBHMFG_00984 7.2e-58 S Protein of unknown function (DUF3039)
HPNBHMFG_00985 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HPNBHMFG_00986 8.5e-134
HPNBHMFG_00987 1.8e-113 yceD S Uncharacterized ACR, COG1399
HPNBHMFG_00988 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HPNBHMFG_00989 1.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HPNBHMFG_00990 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HPNBHMFG_00991 5.7e-92 ilvN 2.2.1.6 E ACT domain
HPNBHMFG_00992 9.7e-247 S Domain of unknown function (DUF4143)
HPNBHMFG_00994 3.2e-95
HPNBHMFG_00995 0.0 yjjK S ABC transporter
HPNBHMFG_00996 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
HPNBHMFG_00997 1.9e-287 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPNBHMFG_00998 1.3e-269 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HPNBHMFG_00999 1.5e-178 S Endonuclease/Exonuclease/phosphatase family
HPNBHMFG_01000 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HPNBHMFG_01001 1.8e-34 CP_0960 S Belongs to the UPF0109 family
HPNBHMFG_01002 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HPNBHMFG_01003 1.9e-148 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HPNBHMFG_01004 2.1e-148 I alpha/beta hydrolase fold
HPNBHMFG_01005 3.2e-138 uhpT EGP Major facilitator Superfamily
HPNBHMFG_01006 1.5e-90 K helix_turn_helix, arabinose operon control protein
HPNBHMFG_01007 2.4e-91 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HPNBHMFG_01008 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HPNBHMFG_01009 8.4e-30 rpmB J Ribosomal L28 family
HPNBHMFG_01010 0.0 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01011 1.9e-229 yxiO S Vacuole effluxer Atg22 like
HPNBHMFG_01012 1.9e-127 gntR K FCD
HPNBHMFG_01013 3.6e-78 gntK 2.7.1.12 F Shikimate kinase
HPNBHMFG_01014 1.3e-227 gnuT EG GntP family permease
HPNBHMFG_01016 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
HPNBHMFG_01017 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HPNBHMFG_01018 2.4e-124 K Bacterial regulatory proteins, tetR family
HPNBHMFG_01019 3.2e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01020 3.8e-229 MA20_36090 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01021 1.7e-137 M Mechanosensitive ion channel
HPNBHMFG_01022 1.3e-175 S CAAX protease self-immunity
HPNBHMFG_01023 3.7e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HPNBHMFG_01024 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HPNBHMFG_01025 5.5e-177 plsC2 2.3.1.51 I Phosphate acyltransferases
HPNBHMFG_01026 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HPNBHMFG_01027 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
HPNBHMFG_01028 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPNBHMFG_01029 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HPNBHMFG_01030 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HPNBHMFG_01031 4.1e-265 S Calcineurin-like phosphoesterase
HPNBHMFG_01034 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HPNBHMFG_01035 7.8e-108 S Protein of unknown function (DUF805)
HPNBHMFG_01036 7e-184
HPNBHMFG_01037 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HPNBHMFG_01038 6.1e-263 EGP Major facilitator Superfamily
HPNBHMFG_01039 7.1e-95 S GtrA-like protein
HPNBHMFG_01040 6.7e-62 S Macrophage migration inhibitory factor (MIF)
HPNBHMFG_01041 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HPNBHMFG_01042 0.0 pepD E Peptidase family C69
HPNBHMFG_01043 1.1e-106 S Phosphatidylethanolamine-binding protein
HPNBHMFG_01044 1e-285 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HPNBHMFG_01045 6e-39 ptsH G PTS HPr component phosphorylation site
HPNBHMFG_01046 4.9e-185 K helix_turn _helix lactose operon repressor
HPNBHMFG_01047 1.9e-193 holB 2.7.7.7 L DNA polymerase III
HPNBHMFG_01048 9.2e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HPNBHMFG_01049 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HPNBHMFG_01050 6.2e-191 3.6.1.27 I PAP2 superfamily
HPNBHMFG_01051 8.5e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
HPNBHMFG_01052 7.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HPNBHMFG_01053 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HPNBHMFG_01054 0.0 S Beta-L-arabinofuranosidase, GH127
HPNBHMFG_01055 1.9e-156 U Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01056 9.1e-170 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01057 8.2e-246 G Bacterial extracellular solute-binding protein
HPNBHMFG_01058 6e-204 abf G Glycosyl hydrolases family 43
HPNBHMFG_01059 4.1e-195 K helix_turn _helix lactose operon repressor
HPNBHMFG_01060 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
HPNBHMFG_01061 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HPNBHMFG_01062 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
HPNBHMFG_01063 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HPNBHMFG_01064 1.4e-300 S Calcineurin-like phosphoesterase
HPNBHMFG_01065 9.3e-115
HPNBHMFG_01066 2.7e-48 yitI S Acetyltransferase (GNAT) domain
HPNBHMFG_01067 7.2e-211 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HPNBHMFG_01068 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
HPNBHMFG_01069 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HPNBHMFG_01070 2.2e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HPNBHMFG_01071 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HPNBHMFG_01072 1.1e-96 K Bacterial regulatory proteins, tetR family
HPNBHMFG_01073 1.6e-193 S Psort location CytoplasmicMembrane, score
HPNBHMFG_01074 4.9e-218 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
HPNBHMFG_01075 3e-55 S TIGRFAM helicase secretion neighborhood TadE-like protein
HPNBHMFG_01076 5.1e-60 U TadE-like protein
HPNBHMFG_01077 1.3e-42 S Protein of unknown function (DUF4244)
HPNBHMFG_01078 1.8e-87 gspF NU Type II secretion system (T2SS), protein F
HPNBHMFG_01079 1.6e-129 U Type ii secretion system
HPNBHMFG_01080 5.2e-184 cpaF U Type II IV secretion system protein
HPNBHMFG_01081 5.5e-141 cpaE D bacterial-type flagellum organization
HPNBHMFG_01083 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HPNBHMFG_01084 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HPNBHMFG_01085 2.5e-90
HPNBHMFG_01086 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HPNBHMFG_01087 1.5e-208 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HPNBHMFG_01088 0.0 G Bacterial Ig-like domain (group 4)
HPNBHMFG_01089 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
HPNBHMFG_01090 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HPNBHMFG_01091 9.3e-147 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01092 3.1e-167 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01093 4.3e-07 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01094 1.1e-242 G Bacterial extracellular solute-binding protein
HPNBHMFG_01095 1.1e-192 K Periplasmic binding protein domain
HPNBHMFG_01096 0.0 ubiB S ABC1 family
HPNBHMFG_01097 1e-27 S granule-associated protein
HPNBHMFG_01098 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HPNBHMFG_01099 8.6e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HPNBHMFG_01100 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HPNBHMFG_01101 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HPNBHMFG_01102 1e-54 glnB K Nitrogen regulatory protein P-II
HPNBHMFG_01103 1.2e-236 amt U Ammonium Transporter Family
HPNBHMFG_01104 8.6e-168 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HPNBHMFG_01105 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
HPNBHMFG_01107 6.1e-196 XK27_01805 M Glycosyltransferase like family 2
HPNBHMFG_01108 3.4e-305 pepD E Peptidase family C69
HPNBHMFG_01111 6e-38 nrdH O Glutaredoxin
HPNBHMFG_01112 1.2e-225 S Putative ABC-transporter type IV
HPNBHMFG_01113 0.0 pip S YhgE Pip domain protein
HPNBHMFG_01114 6.5e-280 pip S YhgE Pip domain protein
HPNBHMFG_01115 5.4e-89 K Psort location Cytoplasmic, score 8.87
HPNBHMFG_01116 1.1e-61 S FMN_bind
HPNBHMFG_01117 2.2e-148 macB V ABC transporter, ATP-binding protein
HPNBHMFG_01118 1.6e-201 Z012_06715 V FtsX-like permease family
HPNBHMFG_01120 8e-220 macB_2 V ABC transporter permease
HPNBHMFG_01121 1.2e-230 S Predicted membrane protein (DUF2318)
HPNBHMFG_01122 1.4e-92 tpd P Fe2+ transport protein
HPNBHMFG_01123 1.6e-292 efeU_1 P Iron permease FTR1 family
HPNBHMFG_01124 4.4e-237 G MFS/sugar transport protein
HPNBHMFG_01125 2e-116 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HPNBHMFG_01126 2.5e-311 lmrA2 V ABC transporter transmembrane region
HPNBHMFG_01127 2.1e-285 lmrA1 V ABC transporter, ATP-binding protein
HPNBHMFG_01128 1.9e-57 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HPNBHMFG_01129 2.6e-178 1.1.1.65 C Aldo/keto reductase family
HPNBHMFG_01130 3.8e-26 thiS 2.8.1.10 H ThiS family
HPNBHMFG_01131 3.2e-127 thiF 2.7.7.73, 2.7.7.80 H ThiF family
HPNBHMFG_01132 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HPNBHMFG_01133 9.9e-275 cycA E Amino acid permease
HPNBHMFG_01134 1.5e-18
HPNBHMFG_01135 6.3e-80 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01136 1.1e-252 M domain protein
HPNBHMFG_01137 0.0 inlJ M domain protein
HPNBHMFG_01138 3.1e-176 3.4.22.70 M Sortase family
HPNBHMFG_01139 5e-79 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01140 1.7e-226 P Sodium/hydrogen exchanger family
HPNBHMFG_01141 0.0 V FtsX-like permease family
HPNBHMFG_01142 5.4e-270 aroP E aromatic amino acid transport protein AroP K03293
HPNBHMFG_01143 8.3e-12 S Protein of unknown function, DUF624
HPNBHMFG_01144 1.5e-186 K helix_turn _helix lactose operon repressor
HPNBHMFG_01145 6.5e-35 G beta-mannosidase
HPNBHMFG_01146 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HPNBHMFG_01147 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPNBHMFG_01148 1.8e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HPNBHMFG_01149 7.9e-252 yhjE EGP Sugar (and other) transporter
HPNBHMFG_01150 3.3e-270 scrT G Transporter major facilitator family protein
HPNBHMFG_01151 4.9e-10 S Protein of unknown function, DUF624
HPNBHMFG_01152 3.1e-297 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HPNBHMFG_01153 1.1e-195 K helix_turn _helix lactose operon repressor
HPNBHMFG_01154 1.4e-29 E Receptor family ligand binding region
HPNBHMFG_01155 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPNBHMFG_01156 2.6e-148 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HPNBHMFG_01157 1.4e-131 clcA P Voltage gated chloride channel
HPNBHMFG_01158 9.3e-108 L Transposase and inactivated derivatives
HPNBHMFG_01159 3.8e-29 L transposase activity
HPNBHMFG_01160 9.8e-155 clcA P Voltage gated chloride channel
HPNBHMFG_01161 3.5e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HPNBHMFG_01162 4.1e-206 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HPNBHMFG_01163 0.0 pip S YhgE Pip domain protein
HPNBHMFG_01164 0.0 pip S YhgE Pip domain protein
HPNBHMFG_01165 2e-169 yddG EG EamA-like transporter family
HPNBHMFG_01166 3.2e-65 K Helix-turn-helix XRE-family like proteins
HPNBHMFG_01168 4.7e-162 htpX O Belongs to the peptidase M48B family
HPNBHMFG_01169 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HPNBHMFG_01170 3.9e-187 ansA 3.5.1.1 EJ Asparaginase
HPNBHMFG_01171 0.0 cadA P E1-E2 ATPase
HPNBHMFG_01172 1.5e-283 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HPNBHMFG_01173 1e-267 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HPNBHMFG_01174 1.2e-36 K helix_turn_helix, Lux Regulon
HPNBHMFG_01175 2.4e-22 2.7.13.3 T Histidine kinase
HPNBHMFG_01180 1.5e-159 yicL EG EamA-like transporter family
HPNBHMFG_01181 2.3e-193 pldB 3.1.1.5 I Serine aminopeptidase, S33
HPNBHMFG_01182 3.2e-113 K helix_turn_helix, Lux Regulon
HPNBHMFG_01183 3.5e-225 2.7.13.3 T Histidine kinase
HPNBHMFG_01184 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HPNBHMFG_01185 1.2e-131 fhaA T Protein of unknown function (DUF2662)
HPNBHMFG_01186 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HPNBHMFG_01187 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HPNBHMFG_01188 9.8e-275 rodA D Belongs to the SEDS family
HPNBHMFG_01189 1.8e-265 pbpA M penicillin-binding protein
HPNBHMFG_01190 5.8e-177 T Protein tyrosine kinase
HPNBHMFG_01191 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HPNBHMFG_01192 8.7e-116 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HPNBHMFG_01193 8.7e-209 srtA 3.4.22.70 M Sortase family
HPNBHMFG_01194 2.6e-141 S Bacterial protein of unknown function (DUF881)
HPNBHMFG_01195 3.1e-57 crgA D Involved in cell division
HPNBHMFG_01196 2.3e-238 L ribosomal rna small subunit methyltransferase
HPNBHMFG_01197 3.1e-147 gluP 3.4.21.105 S Rhomboid family
HPNBHMFG_01198 3.4e-35
HPNBHMFG_01199 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HPNBHMFG_01200 1.7e-63 I Sterol carrier protein
HPNBHMFG_01201 2.2e-34 S Protein of unknown function (DUF3073)
HPNBHMFG_01202 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPNBHMFG_01203 2.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HPNBHMFG_01204 0.0 yjjP S Threonine/Serine exporter, ThrE
HPNBHMFG_01205 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HPNBHMFG_01206 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HPNBHMFG_01207 2.1e-241 ytfL P Transporter associated domain
HPNBHMFG_01208 3.4e-188 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HPNBHMFG_01209 3.1e-101 S Protein of unknown function DUF45
HPNBHMFG_01213 2.9e-58 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HPNBHMFG_01214 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HPNBHMFG_01215 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
HPNBHMFG_01216 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPNBHMFG_01217 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HPNBHMFG_01218 6.2e-90 S Protein of unknown function (DUF721)
HPNBHMFG_01219 3.7e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HPNBHMFG_01220 1e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HPNBHMFG_01221 6.6e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HPNBHMFG_01222 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HPNBHMFG_01223 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
HPNBHMFG_01224 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
HPNBHMFG_01225 1.5e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HPNBHMFG_01226 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HPNBHMFG_01227 2e-202 parB K Belongs to the ParB family
HPNBHMFG_01228 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HPNBHMFG_01229 7e-14 S Psort location Extracellular, score 8.82
HPNBHMFG_01231 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
HPNBHMFG_01232 4e-13 S Domain of unknown function (DUF4143)
HPNBHMFG_01233 0.0 murJ KLT MviN-like protein
HPNBHMFG_01234 8.6e-304 murJ KLT MviN-like protein
HPNBHMFG_01235 0.0 M Conserved repeat domain
HPNBHMFG_01236 6.3e-122 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HPNBHMFG_01237 5e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HPNBHMFG_01238 2.6e-109 S LytR cell envelope-related transcriptional attenuator
HPNBHMFG_01239 3.6e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HPNBHMFG_01240 7.8e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HPNBHMFG_01241 1.6e-197 S G5
HPNBHMFG_01243 7.5e-151 O Thioredoxin
HPNBHMFG_01244 0.0 KLT Protein tyrosine kinase
HPNBHMFG_01245 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
HPNBHMFG_01246 4.5e-26 cysB 4.2.1.22 EGP Major facilitator Superfamily
HPNBHMFG_01247 4.6e-43 cysB 4.2.1.22 EGP Major facilitator Superfamily
HPNBHMFG_01248 1e-11
HPNBHMFG_01249 8e-58 yccF S Inner membrane component domain
HPNBHMFG_01250 1.2e-118 K Bacterial regulatory proteins, tetR family
HPNBHMFG_01251 3e-213 G Transmembrane secretion effector
HPNBHMFG_01252 1.6e-16 K addiction module antidote protein HigA
HPNBHMFG_01253 2.5e-239 S HipA-like C-terminal domain
HPNBHMFG_01254 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HPNBHMFG_01255 5.9e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HPNBHMFG_01256 1.7e-262 pip 3.4.11.5 S alpha/beta hydrolase fold
HPNBHMFG_01257 0.0 tcsS2 T Histidine kinase
HPNBHMFG_01258 4.7e-129 K helix_turn_helix, Lux Regulon
HPNBHMFG_01259 0.0 MV MacB-like periplasmic core domain
HPNBHMFG_01260 1.6e-140 V ABC transporter, ATP-binding protein
HPNBHMFG_01261 8.2e-193 K helix_turn_helix ASNC type
HPNBHMFG_01262 2e-149 P Cobalt transport protein
HPNBHMFG_01263 2.5e-305 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HPNBHMFG_01264 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
HPNBHMFG_01265 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
HPNBHMFG_01266 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HPNBHMFG_01267 1.5e-82 yraN L Belongs to the UPF0102 family
HPNBHMFG_01268 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
HPNBHMFG_01269 5.9e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HPNBHMFG_01270 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HPNBHMFG_01271 5.2e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HPNBHMFG_01272 4.8e-117 safC S O-methyltransferase
HPNBHMFG_01273 3.3e-245 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HPNBHMFG_01276 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HPNBHMFG_01277 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPNBHMFG_01278 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HPNBHMFG_01279 0.0 E ABC transporter, substrate-binding protein, family 5
HPNBHMFG_01280 7.6e-251 EGP Major facilitator Superfamily
HPNBHMFG_01281 1.2e-172 yjfF U Branched-chain amino acid transport system / permease component
HPNBHMFG_01282 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
HPNBHMFG_01283 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
HPNBHMFG_01284 2.4e-165 G Periplasmic binding protein domain
HPNBHMFG_01285 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
HPNBHMFG_01286 9.8e-286 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HPNBHMFG_01287 1.4e-133 KT Transcriptional regulatory protein, C terminal
HPNBHMFG_01288 2e-250 rarA L Recombination factor protein RarA
HPNBHMFG_01289 0.0 L DEAD DEAH box helicase
HPNBHMFG_01290 4.3e-191 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HPNBHMFG_01291 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01292 3.1e-111 gluC E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01293 4.4e-152 gluB ET Belongs to the bacterial solute-binding protein 3 family
HPNBHMFG_01294 6.2e-137 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HPNBHMFG_01295 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
HPNBHMFG_01296 5.5e-281 glnP E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01297 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HPNBHMFG_01298 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HPNBHMFG_01299 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HPNBHMFG_01300 1e-139 3.5.2.10 S Creatinine amidohydrolase
HPNBHMFG_01301 5e-246 proP EGP Sugar (and other) transporter
HPNBHMFG_01302 4.7e-285 purR QT Purine catabolism regulatory protein-like family
HPNBHMFG_01303 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
HPNBHMFG_01304 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HPNBHMFG_01305 4.6e-188 uspA T Belongs to the universal stress protein A family
HPNBHMFG_01306 1.2e-182 S Protein of unknown function (DUF3027)
HPNBHMFG_01307 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
HPNBHMFG_01308 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPNBHMFG_01309 6.8e-133 KT Response regulator receiver domain protein
HPNBHMFG_01310 1.3e-124
HPNBHMFG_01312 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HPNBHMFG_01313 8.5e-77 S LytR cell envelope-related transcriptional attenuator
HPNBHMFG_01314 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HPNBHMFG_01315 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
HPNBHMFG_01316 4.2e-175 S Protein of unknown function DUF58
HPNBHMFG_01317 1.4e-90
HPNBHMFG_01318 4.7e-191 S von Willebrand factor (vWF) type A domain
HPNBHMFG_01319 5e-182 S von Willebrand factor (vWF) type A domain
HPNBHMFG_01320 1.3e-62
HPNBHMFG_01321 1.3e-276 S PGAP1-like protein
HPNBHMFG_01322 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HPNBHMFG_01323 0.0 S Lysylphosphatidylglycerol synthase TM region
HPNBHMFG_01324 1.4e-41 hup L Belongs to the bacterial histone-like protein family
HPNBHMFG_01325 3.9e-57
HPNBHMFG_01326 9.7e-141 C FMN binding
HPNBHMFG_01327 7.2e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HPNBHMFG_01328 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HPNBHMFG_01329 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
HPNBHMFG_01330 1.5e-300 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HPNBHMFG_01331 3.8e-282 arc O AAA ATPase forming ring-shaped complexes
HPNBHMFG_01332 3.5e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HPNBHMFG_01333 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HPNBHMFG_01334 7.1e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HPNBHMFG_01335 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HPNBHMFG_01336 4.1e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HPNBHMFG_01337 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HPNBHMFG_01338 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HPNBHMFG_01340 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HPNBHMFG_01341 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HPNBHMFG_01342 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HPNBHMFG_01343 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
HPNBHMFG_01344 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HPNBHMFG_01345 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HPNBHMFG_01346 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HPNBHMFG_01347 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HPNBHMFG_01348 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HPNBHMFG_01349 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HPNBHMFG_01350 1.1e-187 yocS S SBF-like CPA transporter family (DUF4137)
HPNBHMFG_01352 1.5e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
HPNBHMFG_01353 6.5e-226 M Glycosyl transferase 4-like domain
HPNBHMFG_01354 8.2e-227 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HPNBHMFG_01355 4.3e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HPNBHMFG_01356 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HPNBHMFG_01357 1.5e-33
HPNBHMFG_01358 3.6e-307 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HPNBHMFG_01359 1.4e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HPNBHMFG_01360 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HPNBHMFG_01361 3.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HPNBHMFG_01362 2.1e-247 EGP Major facilitator Superfamily
HPNBHMFG_01363 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HPNBHMFG_01364 1.1e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
HPNBHMFG_01365 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
HPNBHMFG_01366 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HPNBHMFG_01367 2.5e-203 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
HPNBHMFG_01368 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HPNBHMFG_01369 4.4e-88 zur P Belongs to the Fur family
HPNBHMFG_01370 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HPNBHMFG_01371 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HPNBHMFG_01372 1.2e-183 adh3 C Zinc-binding dehydrogenase
HPNBHMFG_01373 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HPNBHMFG_01374 6.8e-257 macB_8 V MacB-like periplasmic core domain
HPNBHMFG_01375 4.4e-147 M Conserved repeat domain
HPNBHMFG_01376 9.6e-135 V ATPases associated with a variety of cellular activities
HPNBHMFG_01377 4.3e-75
HPNBHMFG_01378 2.4e-15 S Domain of unknown function (DUF4143)
HPNBHMFG_01379 5.3e-127 XK27_08050 O prohibitin homologues
HPNBHMFG_01380 1.4e-43 XAC3035 O Glutaredoxin
HPNBHMFG_01381 2.8e-15 P Belongs to the ABC transporter superfamily
HPNBHMFG_01382 4.3e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HPNBHMFG_01383 4.3e-13 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HPNBHMFG_01384 7e-220 mtnE 2.6.1.83 E Aminotransferase class I and II
HPNBHMFG_01385 2.4e-97 metI P Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_01386 6.3e-180 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HPNBHMFG_01387 2.3e-151 metQ M NLPA lipoprotein
HPNBHMFG_01388 9.1e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HPNBHMFG_01389 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
HPNBHMFG_01390 4.1e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HPNBHMFG_01391 3.6e-120 E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01392 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01393 7.7e-101 K acetyltransferase
HPNBHMFG_01397 0.0 tetP J Elongation factor G, domain IV
HPNBHMFG_01399 4e-215 ybiR P Citrate transporter
HPNBHMFG_01400 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HPNBHMFG_01401 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HPNBHMFG_01402 8.9e-270 yhdG E aromatic amino acid transport protein AroP K03293
HPNBHMFG_01403 3e-101 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HPNBHMFG_01404 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HPNBHMFG_01405 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HPNBHMFG_01406 0.0 macB_2 V ATPases associated with a variety of cellular activities
HPNBHMFG_01407 3.2e-217 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HPNBHMFG_01408 9.3e-189 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HPNBHMFG_01409 4e-139 sapF E ATPases associated with a variety of cellular activities
HPNBHMFG_01410 1.4e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
HPNBHMFG_01411 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01412 1.3e-166 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01413 2.3e-293 E ABC transporter, substrate-binding protein, family 5
HPNBHMFG_01414 1.6e-241 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HPNBHMFG_01415 5.9e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HPNBHMFG_01416 1.1e-275 G Bacterial extracellular solute-binding protein
HPNBHMFG_01417 2.2e-246 G Bacterial extracellular solute-binding protein
HPNBHMFG_01418 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
HPNBHMFG_01419 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_01423 1.5e-208 L Phage integrase, N-terminal SAM-like domain
HPNBHMFG_01424 8.5e-14
HPNBHMFG_01425 7.2e-190 L Psort location Cytoplasmic, score
HPNBHMFG_01427 3.9e-08
HPNBHMFG_01428 9.2e-30
HPNBHMFG_01429 1.4e-277 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HPNBHMFG_01430 2e-67
HPNBHMFG_01431 4e-259 S AAA domain
HPNBHMFG_01432 1.4e-199 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HPNBHMFG_01433 2.9e-237 5.4.99.9 H Flavin containing amine oxidoreductase
HPNBHMFG_01434 9.3e-37
HPNBHMFG_01435 2.1e-80 S enterobacterial common antigen metabolic process
HPNBHMFG_01436 7.7e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPNBHMFG_01437 1.1e-262 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPNBHMFG_01438 1.9e-161 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPNBHMFG_01439 1.9e-75 rgpC GM Transport permease protein
HPNBHMFG_01440 2.9e-107 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HPNBHMFG_01441 1.4e-87 M Polysaccharide pyruvyl transferase
HPNBHMFG_01442 1.3e-110 wbbX GT2,GT4 M transferase activity, transferring glycosyl groups
HPNBHMFG_01443 1.2e-76 rfbN GT2 M Glycosyl transferase family 2
HPNBHMFG_01444 9.9e-114 M Glycosyltransferase like family 2
HPNBHMFG_01445 4.2e-302 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HPNBHMFG_01446 2.9e-201 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPNBHMFG_01447 6.4e-24 S Addiction module toxin, RelE StbE family
HPNBHMFG_01448 1.1e-17 relB L RelB antitoxin
HPNBHMFG_01449 3.5e-61
HPNBHMFG_01450 1.1e-197 K helix_turn _helix lactose operon repressor
HPNBHMFG_01451 2.8e-166 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HPNBHMFG_01452 1.1e-259 EGP Major Facilitator Superfamily
HPNBHMFG_01453 4.8e-174 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HPNBHMFG_01454 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HPNBHMFG_01455 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HPNBHMFG_01456 9.7e-70 ssb1 L Single-stranded DNA-binding protein
HPNBHMFG_01457 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HPNBHMFG_01458 1.7e-70 rplI J Binds to the 23S rRNA
HPNBHMFG_01460 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HPNBHMFG_01461 1.2e-08 M Protein of unknown function (DUF3152)
HPNBHMFG_01462 3.3e-54 M Protein of unknown function (DUF3152)
HPNBHMFG_01463 6.9e-209 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HPNBHMFG_01464 2.5e-80
HPNBHMFG_01465 1.4e-147 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HPNBHMFG_01466 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HPNBHMFG_01467 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HPNBHMFG_01468 2e-131 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
HPNBHMFG_01469 6.8e-171 rmuC S RmuC family
HPNBHMFG_01470 0.0 N Bacterial Ig-like domain 2
HPNBHMFG_01471 0.0 scrB 3.2.1.26, 3.2.1.97 GH101,GH32 N Glycosyl hydrolases family 43
HPNBHMFG_01472 8.4e-114 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HPNBHMFG_01473 1.2e-145 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HPNBHMFG_01474 5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPNBHMFG_01475 8.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HPNBHMFG_01476 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HPNBHMFG_01477 2.7e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
HPNBHMFG_01478 2.1e-51 S Protein of unknown function (DUF2469)
HPNBHMFG_01479 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HPNBHMFG_01480 9.3e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HPNBHMFG_01481 1.3e-79 K helix_turn_helix ASNC type
HPNBHMFG_01482 3e-69 tyrA 5.4.99.5 E Chorismate mutase type II
HPNBHMFG_01483 0.0 S domain protein
HPNBHMFG_01484 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HPNBHMFG_01485 1e-287 E Bacterial extracellular solute-binding proteins, family 5 Middle
HPNBHMFG_01486 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HPNBHMFG_01487 4.9e-134 KT Transcriptional regulatory protein, C terminal
HPNBHMFG_01488 4.9e-134
HPNBHMFG_01489 3.6e-97 mntP P Probably functions as a manganese efflux pump
HPNBHMFG_01490 9.7e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HPNBHMFG_01491 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HPNBHMFG_01492 7.1e-175 M LPXTG-motif cell wall anchor domain protein
HPNBHMFG_01493 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
HPNBHMFG_01494 5.7e-192 yfdV S Membrane transport protein
HPNBHMFG_01495 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HPNBHMFG_01498 2.8e-09
HPNBHMFG_01501 2.4e-39 O prohibitin homologues
HPNBHMFG_01506 3.7e-51 ssb1 L Single-stranded DNA-binding protein
HPNBHMFG_01507 4.1e-08
HPNBHMFG_01510 5.7e-33 V HNH endonuclease
HPNBHMFG_01511 2.8e-30 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HPNBHMFG_01512 2.1e-42 S Protein of unknwon function (DUF3310)
HPNBHMFG_01514 6.7e-08
HPNBHMFG_01517 1.1e-08 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPNBHMFG_01520 1.2e-19
HPNBHMFG_01522 7.7e-35 L HNH endonuclease
HPNBHMFG_01523 1e-07
HPNBHMFG_01524 1.6e-239 S Terminase
HPNBHMFG_01525 2.2e-181 S Phage portal protein, SPP1 Gp6-like
HPNBHMFG_01526 2.3e-167
HPNBHMFG_01527 7.4e-28
HPNBHMFG_01528 3.3e-145 V Phage capsid family
HPNBHMFG_01530 7.9e-47 S Phage protein Gp19/Gp15/Gp42
HPNBHMFG_01531 4.5e-31
HPNBHMFG_01533 1e-20
HPNBHMFG_01534 8.1e-60 eae N domain, Protein
HPNBHMFG_01535 7.6e-28
HPNBHMFG_01536 1.3e-29
HPNBHMFG_01537 2.1e-82 NT phage tail tape measure protein
HPNBHMFG_01538 5.1e-70 S phage tail
HPNBHMFG_01539 1.1e-226 S Prophage endopeptidase tail
HPNBHMFG_01542 1.7e-38
HPNBHMFG_01543 1.3e-133
HPNBHMFG_01545 2.6e-84 L reverse transcriptase
HPNBHMFG_01547 8.8e-16
HPNBHMFG_01548 3.7e-107 M Glycosyl hydrolases family 25
HPNBHMFG_01549 1.1e-27 S Putative phage holin Dp-1
HPNBHMFG_01550 7.2e-38
HPNBHMFG_01551 2.4e-43 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
HPNBHMFG_01552 2.1e-93 L Phage integrase family
HPNBHMFG_01554 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HPNBHMFG_01555 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
HPNBHMFG_01556 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPNBHMFG_01557 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HPNBHMFG_01558 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HPNBHMFG_01559 1.4e-308 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HPNBHMFG_01560 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HPNBHMFG_01561 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HPNBHMFG_01562 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HPNBHMFG_01563 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HPNBHMFG_01564 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HPNBHMFG_01565 1.1e-194
HPNBHMFG_01566 3.3e-178
HPNBHMFG_01567 9.3e-170 trxA2 O Tetratricopeptide repeat
HPNBHMFG_01568 1.8e-121 cyaA 4.6.1.1 S CYTH
HPNBHMFG_01570 8e-64 psp1 3.5.99.10 J Endoribonuclease L-PSP
HPNBHMFG_01571 5.7e-272 mmuP E amino acid
HPNBHMFG_01572 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HPNBHMFG_01573 2e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HPNBHMFG_01574 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
HPNBHMFG_01575 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HPNBHMFG_01576 2e-285 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HPNBHMFG_01577 2.1e-210 K helix_turn _helix lactose operon repressor
HPNBHMFG_01578 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HPNBHMFG_01579 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HPNBHMFG_01580 1.8e-297 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HPNBHMFG_01581 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HPNBHMFG_01582 0.0 cydD V ABC transporter transmembrane region
HPNBHMFG_01583 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HPNBHMFG_01584 2.1e-129 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HPNBHMFG_01585 9.1e-240 G Bacterial extracellular solute-binding protein
HPNBHMFG_01586 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_01587 1.1e-195 K helix_turn _helix lactose operon repressor
HPNBHMFG_01588 2.3e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HPNBHMFG_01589 8.4e-167 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HPNBHMFG_01590 2.6e-125 L Protein of unknown function (DUF1524)
HPNBHMFG_01591 1.9e-242 T Diguanylate cyclase (GGDEF) domain protein
HPNBHMFG_01592 6.8e-284 EGP Major facilitator Superfamily
HPNBHMFG_01593 1.3e-46
HPNBHMFG_01594 1.6e-140 S Endonuclease/Exonuclease/phosphatase family
HPNBHMFG_01595 1.7e-84 3.1.3.48 T Low molecular weight phosphatase family
HPNBHMFG_01596 9.3e-224 pflA S Protein of unknown function (DUF4012)
HPNBHMFG_01597 3.8e-191 wcoI DM Psort location CytoplasmicMembrane, score
HPNBHMFG_01598 2.8e-14
HPNBHMFG_01599 9.5e-106
HPNBHMFG_01601 2.9e-49 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HPNBHMFG_01602 1.9e-147 L Transposase and inactivated derivatives IS30 family
HPNBHMFG_01603 3.1e-107 3.1.3.48 T Low molecular weight phosphatase family
HPNBHMFG_01604 4.6e-114 S Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_01606 6.9e-167 rgpAc GT4 M Domain of unknown function (DUF1972)
HPNBHMFG_01607 1.6e-171 rfaG3 M Glycosyltransferase, group 1 family protein
HPNBHMFG_01608 5.3e-34 2.3.1.79 S Hexapeptide repeat of succinyl-transferase
HPNBHMFG_01609 4.9e-33 M Glycosyltransferase like family 2
HPNBHMFG_01610 2e-17 M O-Antigen ligase
HPNBHMFG_01611 7.5e-139 S Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_01612 3e-119 C Polysaccharide pyruvyl transferase
HPNBHMFG_01613 1.9e-52 S Core-2 I-Branching enzyme
HPNBHMFG_01615 1.8e-195 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HPNBHMFG_01616 8.7e-265 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HPNBHMFG_01617 4.6e-171 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HPNBHMFG_01618 2.7e-39 S Bacteriophage abortive infection AbiH
HPNBHMFG_01619 4.3e-167 L Transposase and inactivated derivatives IS30 family
HPNBHMFG_01621 5.1e-84 K Helix-turn-helix domain protein
HPNBHMFG_01622 1.7e-26 tnp7109-21 L Integrase core domain
HPNBHMFG_01623 1.1e-29 S Abi-like protein
HPNBHMFG_01624 2.1e-60 L Helix-turn-helix domain
HPNBHMFG_01625 2.1e-120 insK L Integrase core domain
HPNBHMFG_01626 1.2e-25 K Transposase IS116 IS110 IS902
HPNBHMFG_01628 5.5e-09
HPNBHMFG_01629 2.4e-31
HPNBHMFG_01631 2.5e-29 S AAA domain, putative AbiEii toxin, Type IV TA system
HPNBHMFG_01633 8.2e-115 ysdA S Protein of unknown function (DUF1294)
HPNBHMFG_01634 1.1e-243 S Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_01635 4.5e-151 V Abi-like protein
HPNBHMFG_01637 2.4e-54 yccF S Inner membrane component domain
HPNBHMFG_01638 8.3e-15 wcoI DM Psort location CytoplasmicMembrane, score
HPNBHMFG_01639 1.4e-184 K Psort location Cytoplasmic, score
HPNBHMFG_01640 3e-270 G Bacterial extracellular solute-binding protein
HPNBHMFG_01641 1.7e-162 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01642 6.5e-148 P Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01643 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPNBHMFG_01644 9.4e-90 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HPNBHMFG_01645 5.1e-154 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HPNBHMFG_01647 9.2e-89
HPNBHMFG_01648 5.2e-168 S G5
HPNBHMFG_01650 1.1e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HPNBHMFG_01651 3.5e-114 F Domain of unknown function (DUF4916)
HPNBHMFG_01652 3.4e-160 mhpC I Alpha/beta hydrolase family
HPNBHMFG_01653 8.1e-207 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HPNBHMFG_01654 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HPNBHMFG_01655 1.5e-236 S Uncharacterized conserved protein (DUF2183)
HPNBHMFG_01656 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HPNBHMFG_01657 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HPNBHMFG_01658 2.9e-86 J TM2 domain
HPNBHMFG_01659 1.9e-214 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HPNBHMFG_01660 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
HPNBHMFG_01661 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HPNBHMFG_01662 1.4e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HPNBHMFG_01663 2e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HPNBHMFG_01664 3.4e-141 glpR K DeoR C terminal sensor domain
HPNBHMFG_01665 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HPNBHMFG_01666 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HPNBHMFG_01667 1.1e-23 lmrB EGP Major facilitator Superfamily
HPNBHMFG_01668 7.1e-43 gcvR T Belongs to the UPF0237 family
HPNBHMFG_01669 5.5e-253 S UPF0210 protein
HPNBHMFG_01670 2.5e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HPNBHMFG_01671 1.3e-181 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HPNBHMFG_01672 1.5e-99
HPNBHMFG_01673 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPNBHMFG_01674 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HPNBHMFG_01675 3.3e-87 T Forkhead associated domain
HPNBHMFG_01676 1.7e-78 B Belongs to the OprB family
HPNBHMFG_01677 3.8e-162 3.1.3.16 T Sigma factor PP2C-like phosphatases
HPNBHMFG_01678 0.0 E Transglutaminase-like superfamily
HPNBHMFG_01679 8.3e-221 S Protein of unknown function DUF58
HPNBHMFG_01680 3.1e-227 S ATPase family associated with various cellular activities (AAA)
HPNBHMFG_01681 0.0 S Fibronectin type 3 domain
HPNBHMFG_01682 1.2e-266 KLT Protein tyrosine kinase
HPNBHMFG_01683 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HPNBHMFG_01684 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HPNBHMFG_01685 1.7e-246 G Major Facilitator Superfamily
HPNBHMFG_01686 4.1e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HPNBHMFG_01687 1.1e-38 csoR S Metal-sensitive transcriptional repressor
HPNBHMFG_01688 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HPNBHMFG_01689 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HPNBHMFG_01690 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HPNBHMFG_01691 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HPNBHMFG_01692 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HPNBHMFG_01693 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HPNBHMFG_01694 7.7e-291 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HPNBHMFG_01695 1.7e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HPNBHMFG_01696 2.2e-173 T GHKL domain
HPNBHMFG_01697 2.5e-57 T GHKL domain
HPNBHMFG_01698 1.4e-130 KT LytTr DNA-binding domain
HPNBHMFG_01699 1.1e-270 3.2.1.21 GH3 G Glycosyl hydrolase family 3 C-terminal domain
HPNBHMFG_01700 2e-307 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N terminal domain
HPNBHMFG_01701 3.2e-63
HPNBHMFG_01702 0.0 3.2.1.23 G Domain of unknown function (DUF4982)
HPNBHMFG_01703 2.7e-111 S Psort location CytoplasmicMembrane, score
HPNBHMFG_01704 7e-53 S Protein of unknown function (DUF4235)
HPNBHMFG_01705 7.5e-137 G Phosphoglycerate mutase family
HPNBHMFG_01706 5.1e-31 K purine nucleotide biosynthetic process
HPNBHMFG_01707 2e-68 K Psort location Cytoplasmic, score
HPNBHMFG_01708 6.1e-199 K Psort location Cytoplasmic, score
HPNBHMFG_01709 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HPNBHMFG_01710 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HPNBHMFG_01711 7.3e-115 S Protein of unknown function, DUF624
HPNBHMFG_01712 2.1e-196 K Periplasmic binding protein domain
HPNBHMFG_01713 1.7e-289 3.2.1.26 GH32 G Glycosyl hydrolases family 32
HPNBHMFG_01714 1.3e-251 amyE G Bacterial extracellular solute-binding protein
HPNBHMFG_01715 1.2e-09 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HPNBHMFG_01716 1.1e-184 K Psort location Cytoplasmic, score
HPNBHMFG_01717 2e-152 rafG G ABC transporter permease
HPNBHMFG_01718 8.2e-138 msmF G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01719 8.2e-185 K Psort location Cytoplasmic, score
HPNBHMFG_01720 3.2e-253 amyE G Bacterial extracellular solute-binding protein
HPNBHMFG_01721 3.5e-226 M Protein of unknown function (DUF2961)
HPNBHMFG_01722 3.9e-267 amyE G Bacterial extracellular solute-binding protein
HPNBHMFG_01723 4.9e-55 S HAD-hyrolase-like
HPNBHMFG_01724 1.3e-152 S AAA domain
HPNBHMFG_01725 7.3e-124 S membrane transporter protein
HPNBHMFG_01726 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
HPNBHMFG_01727 5.5e-144 S Mitochondrial biogenesis AIM24
HPNBHMFG_01728 0.0 dnaK O Heat shock 70 kDa protein
HPNBHMFG_01729 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HPNBHMFG_01730 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
HPNBHMFG_01731 4.5e-115 hspR K transcriptional regulator, MerR family
HPNBHMFG_01732 4.3e-46
HPNBHMFG_01733 3.3e-129 S HAD hydrolase, family IA, variant 3
HPNBHMFG_01735 5.8e-126 dedA S SNARE associated Golgi protein
HPNBHMFG_01736 7.3e-18 3.2.1.78 GH26 G Glycosyl hydrolase family 26
HPNBHMFG_01737 5.2e-190 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HPNBHMFG_01738 1.1e-106
HPNBHMFG_01739 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HPNBHMFG_01740 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HPNBHMFG_01741 6.6e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
HPNBHMFG_01742 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_01743 4.8e-261 lacS G Psort location CytoplasmicMembrane, score 10.00
HPNBHMFG_01744 3.6e-210 GK ROK family
HPNBHMFG_01745 4.2e-242 G Bacterial extracellular solute-binding protein
HPNBHMFG_01746 2.2e-146 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01747 4.4e-164 G ABC transporter permease
HPNBHMFG_01748 3e-173 2.7.1.2 GK ROK family
HPNBHMFG_01749 0.0 G Glycosyl hydrolase family 20, domain 2
HPNBHMFG_01750 2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HPNBHMFG_01751 1.5e-234 nagA 3.5.1.25 G Amidohydrolase family
HPNBHMFG_01752 2.3e-187 lacR K Transcriptional regulator, LacI family
HPNBHMFG_01753 0.0 T Diguanylate cyclase, GGDEF domain
HPNBHMFG_01754 1.9e-250 3.2.1.14 GH18 S Carbohydrate binding domain
HPNBHMFG_01755 0.0 M probably involved in cell wall
HPNBHMFG_01756 1.9e-230 M Protein of unknown function (DUF2961)
HPNBHMFG_01757 1.4e-155 I alpha/beta hydrolase fold
HPNBHMFG_01758 5e-27 S Psort location Cytoplasmic, score 8.87
HPNBHMFG_01759 1.1e-214 lipA I Hydrolase, alpha beta domain protein
HPNBHMFG_01760 0.0 mdlA2 V ABC transporter
HPNBHMFG_01761 0.0 yknV V ABC transporter
HPNBHMFG_01762 3e-125
HPNBHMFG_01763 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_01764 1.4e-223 K helix_turn _helix lactose operon repressor
HPNBHMFG_01765 1.1e-232 G Alpha galactosidase A
HPNBHMFG_01766 0.0 G Alpha-L-arabinofuranosidase C-terminus
HPNBHMFG_01767 2.2e-184 tatD L TatD related DNase
HPNBHMFG_01768 0.0 kup P Transport of potassium into the cell
HPNBHMFG_01769 1e-167 S Glutamine amidotransferase domain
HPNBHMFG_01770 5.1e-150 T HD domain
HPNBHMFG_01771 1.1e-156 V ABC transporter
HPNBHMFG_01772 2.1e-241 V ABC transporter permease
HPNBHMFG_01773 0.0 S Psort location CytoplasmicMembrane, score 9.99
HPNBHMFG_01774 1.5e-102 isp2 3.2.1.96 M CHAP domain
HPNBHMFG_01775 1.9e-21
HPNBHMFG_01776 6.1e-20
HPNBHMFG_01778 3.4e-08 D AAA domain
HPNBHMFG_01779 5.5e-56 D AAA domain
HPNBHMFG_01781 6.9e-36 S Transcription factor WhiB
HPNBHMFG_01782 9.6e-87 S Helix-turn-helix domain
HPNBHMFG_01783 1.8e-19 S Helix-turn-helix domain
HPNBHMFG_01784 4.5e-10
HPNBHMFG_01785 2e-28
HPNBHMFG_01786 6.3e-105
HPNBHMFG_01790 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
HPNBHMFG_01791 8.8e-176 terC P Integral membrane protein, TerC family
HPNBHMFG_01792 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HPNBHMFG_01793 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HPNBHMFG_01794 8.3e-255 rpsA J Ribosomal protein S1
HPNBHMFG_01795 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HPNBHMFG_01796 5.9e-173 P Zinc-uptake complex component A periplasmic
HPNBHMFG_01797 2e-160 znuC P ATPases associated with a variety of cellular activities
HPNBHMFG_01798 1e-140 znuB U ABC 3 transport family
HPNBHMFG_01799 7.3e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HPNBHMFG_01800 3e-102 carD K CarD-like/TRCF domain
HPNBHMFG_01801 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HPNBHMFG_01802 3e-128 T Response regulator receiver domain protein
HPNBHMFG_01803 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPNBHMFG_01804 2.9e-139 ctsW S Phosphoribosyl transferase domain
HPNBHMFG_01805 3.3e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HPNBHMFG_01806 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HPNBHMFG_01807 7.4e-214
HPNBHMFG_01808 0.0 S Glycosyl transferase, family 2
HPNBHMFG_01809 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPNBHMFG_01810 5.7e-208 K Cell envelope-related transcriptional attenuator domain
HPNBHMFG_01812 9e-170 K Cell envelope-related transcriptional attenuator domain
HPNBHMFG_01813 0.0 D FtsK/SpoIIIE family
HPNBHMFG_01814 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HPNBHMFG_01815 5.1e-276 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HPNBHMFG_01816 6.8e-143 yplQ S Haemolysin-III related
HPNBHMFG_01817 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HPNBHMFG_01818 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HPNBHMFG_01819 1.7e-284 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HPNBHMFG_01820 1.8e-91
HPNBHMFG_01822 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HPNBHMFG_01823 7.6e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HPNBHMFG_01824 2e-71 divIC D Septum formation initiator
HPNBHMFG_01825 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HPNBHMFG_01826 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HPNBHMFG_01827 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HPNBHMFG_01828 3.6e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
HPNBHMFG_01829 0.0 S Uncharacterised protein family (UPF0182)
HPNBHMFG_01830 4e-178 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HPNBHMFG_01831 6.2e-40 ybdD S Selenoprotein, putative
HPNBHMFG_01832 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
HPNBHMFG_01833 7.9e-52 azlD E Branched-chain amino acid transport protein (AzlD)
HPNBHMFG_01834 1.1e-141 azlC E AzlC protein
HPNBHMFG_01835 1.3e-87 M Protein of unknown function (DUF3737)
HPNBHMFG_01836 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HPNBHMFG_01837 7.1e-144 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HPNBHMFG_01838 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
HPNBHMFG_01839 6.1e-304 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HPNBHMFG_01840 8.2e-237 patB 4.4.1.8 E Aminotransferase, class I II
HPNBHMFG_01841 4.5e-146 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HPNBHMFG_01842 4.5e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HPNBHMFG_01843 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HPNBHMFG_01844 7.7e-242 S Putative esterase
HPNBHMFG_01845 1.2e-141 ybbL V ATPases associated with a variety of cellular activities
HPNBHMFG_01846 3.9e-134 ybbM V Uncharacterised protein family (UPF0014)
HPNBHMFG_01847 6e-275 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HPNBHMFG_01848 6e-126 S Enoyl-(Acyl carrier protein) reductase
HPNBHMFG_01849 2.4e-226 rutG F Permease family
HPNBHMFG_01850 4.1e-155 3.1.3.73 G Phosphoglycerate mutase family
HPNBHMFG_01851 7e-141 K helix_turn_helix, arabinose operon control protein
HPNBHMFG_01852 1.4e-137 S Sulfite exporter TauE/SafE
HPNBHMFG_01853 1.9e-93 S ECF transporter, substrate-specific component
HPNBHMFG_01854 4.2e-112 2.7.1.48 F uridine kinase
HPNBHMFG_01855 2.5e-172 korD 1.2.7.3 C Domain of unknown function (DUF362)
HPNBHMFG_01856 6.7e-224 C Na H antiporter family protein
HPNBHMFG_01857 2.2e-180 MA20_14895 S Conserved hypothetical protein 698
HPNBHMFG_01858 7e-118
HPNBHMFG_01859 3.7e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HPNBHMFG_01860 5.7e-85 K Cro/C1-type HTH DNA-binding domain
HPNBHMFG_01861 2.6e-65 K Transcriptional regulator PadR-like family
HPNBHMFG_01862 4e-45 yjdF S Protein of unknown function (DUF2992)
HPNBHMFG_01863 7.1e-13 S Cysteine-rich KTR
HPNBHMFG_01864 2.3e-75 phyR K Sigma-70, region 4
HPNBHMFG_01865 3.5e-39 S COG NOG21981 non supervised orthologous group
HPNBHMFG_01866 7.2e-32 L Psort location Cytoplasmic, score 8.87
HPNBHMFG_01867 7.3e-225 L Psort location Cytoplasmic, score 8.87
HPNBHMFG_01868 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HPNBHMFG_01869 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HPNBHMFG_01870 9.1e-119 S Short repeat of unknown function (DUF308)
HPNBHMFG_01871 2.7e-49 S Antitoxin component of a toxin-antitoxin (TA) module
HPNBHMFG_01872 2.9e-54 DJ Addiction module toxin, RelE StbE family
HPNBHMFG_01873 4.5e-13 S Psort location Extracellular, score 8.82
HPNBHMFG_01874 2.9e-232 EGP Major facilitator Superfamily
HPNBHMFG_01875 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HPNBHMFG_01876 2e-269 KLT Domain of unknown function (DUF4032)
HPNBHMFG_01877 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
HPNBHMFG_01878 2.8e-131 K LytTr DNA-binding domain
HPNBHMFG_01879 1.7e-231 T GHKL domain
HPNBHMFG_01880 1.1e-73
HPNBHMFG_01881 1.8e-219 clcA_2 P Voltage gated chloride channel
HPNBHMFG_01882 6.1e-49 S Psort location Cytoplasmic, score
HPNBHMFG_01883 3.4e-138
HPNBHMFG_01884 1.9e-178 3.4.22.70 M Sortase family
HPNBHMFG_01885 7.4e-244 M LPXTG-motif cell wall anchor domain protein
HPNBHMFG_01886 0.0 S LPXTG-motif cell wall anchor domain protein
HPNBHMFG_01887 3.9e-72 S GtrA-like protein
HPNBHMFG_01888 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HPNBHMFG_01889 6.4e-120 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
HPNBHMFG_01890 2.4e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
HPNBHMFG_01891 1.1e-113 vex2 V ABC transporter, ATP-binding protein
HPNBHMFG_01892 2.2e-213 vex1 V Efflux ABC transporter, permease protein
HPNBHMFG_01893 3.9e-238 vex3 V ABC transporter permease
HPNBHMFG_01894 1.2e-34 lacS G Psort location CytoplasmicMembrane, score 10.00
HPNBHMFG_01895 1.1e-38 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HPNBHMFG_01896 5.7e-229 yhjX EGP Major facilitator Superfamily
HPNBHMFG_01897 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HPNBHMFG_01898 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HPNBHMFG_01899 2.3e-88 I alpha/beta hydrolase fold
HPNBHMFG_01900 6.2e-145 cobB2 K Sir2 family
HPNBHMFG_01901 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HPNBHMFG_01902 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HPNBHMFG_01903 2.6e-155 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01904 6.6e-157 G Binding-protein-dependent transport system inner membrane component
HPNBHMFG_01905 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
HPNBHMFG_01906 4e-231 nagC GK ROK family
HPNBHMFG_01907 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HPNBHMFG_01908 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HPNBHMFG_01909 0.0 yjcE P Sodium/hydrogen exchanger family
HPNBHMFG_01910 1.2e-154 ypfH S Phospholipase/Carboxylesterase
HPNBHMFG_01911 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)