ORF_ID e_value Gene_name EC_number CAZy COGs Description
CNPNMHOP_00001 3.9e-142 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
CNPNMHOP_00002 1.9e-62 S Protein of unknown function (DUF4235)
CNPNMHOP_00003 2.9e-136 G Phosphoglycerate mutase family
CNPNMHOP_00004 6.2e-257 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00005 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
CNPNMHOP_00006 2.4e-47 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00007 2e-202 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00008 7e-187 K Periplasmic binding protein-like domain
CNPNMHOP_00009 1.7e-182 K Psort location Cytoplasmic, score
CNPNMHOP_00010 4.1e-153 msmF G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00011 2.6e-152 rafG G ABC transporter permease
CNPNMHOP_00012 1.9e-104 S Protein of unknown function, DUF624
CNPNMHOP_00013 2.9e-13 S Transposon-encoded protein TnpV
CNPNMHOP_00014 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
CNPNMHOP_00015 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
CNPNMHOP_00016 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
CNPNMHOP_00017 4.9e-102 malE G Bacterial extracellular solute-binding protein
CNPNMHOP_00018 1.2e-106 malE G Bacterial extracellular solute-binding protein
CNPNMHOP_00019 3.2e-248 malF G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00020 3.5e-163 malG G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00021 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CNPNMHOP_00022 5.4e-144 S HAD-hyrolase-like
CNPNMHOP_00023 1.4e-142 traX S TraX protein
CNPNMHOP_00024 1.3e-193 K Psort location Cytoplasmic, score
CNPNMHOP_00026 0.0 M cell wall anchor domain protein
CNPNMHOP_00027 4.7e-136 M LPXTG-motif cell wall anchor domain protein
CNPNMHOP_00028 3.7e-183 M Cna protein B-type domain
CNPNMHOP_00029 2e-144 srtC 3.4.22.70 M Sortase family
CNPNMHOP_00030 1.3e-47 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00031 8.2e-78 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00032 3.8e-182 K Psort location Cytoplasmic, score
CNPNMHOP_00033 2e-152 rafG G ABC transporter permease
CNPNMHOP_00034 9.1e-137 msmF G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00035 8.4e-165 K Psort location Cytoplasmic, score
CNPNMHOP_00036 1.5e-250 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00037 3.5e-226 M Protein of unknown function (DUF2961)
CNPNMHOP_00038 1.1e-264 amyE G Bacterial extracellular solute-binding protein
CNPNMHOP_00039 4.9e-55 S HAD-hyrolase-like
CNPNMHOP_00040 2.6e-153 S AAA domain
CNPNMHOP_00041 6e-126 S membrane transporter protein
CNPNMHOP_00042 9e-53 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
CNPNMHOP_00043 3.8e-145 S Mitochondrial biogenesis AIM24
CNPNMHOP_00044 0.0 dnaK O Heat shock 70 kDa protein
CNPNMHOP_00045 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CNPNMHOP_00046 2.1e-159 dnaJ1 O DnaJ molecular chaperone homology domain
CNPNMHOP_00047 4.5e-115 hspR K transcriptional regulator, MerR family
CNPNMHOP_00048 8.6e-47
CNPNMHOP_00049 8.7e-130 S HAD hydrolase, family IA, variant 3
CNPNMHOP_00051 5.8e-126 dedA S SNARE associated Golgi protein
CNPNMHOP_00052 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
CNPNMHOP_00053 6.1e-191 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CNPNMHOP_00054 6.4e-74
CNPNMHOP_00055 2.5e-106
CNPNMHOP_00056 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CNPNMHOP_00057 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
CNPNMHOP_00059 4.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
CNPNMHOP_00060 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_00061 3.9e-263 lacS G Psort location CytoplasmicMembrane, score 10.00
CNPNMHOP_00062 2.8e-210 GK ROK family
CNPNMHOP_00063 6.2e-219 G Bacterial extracellular solute-binding protein
CNPNMHOP_00064 7.5e-147 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00065 9.8e-164 G ABC transporter permease
CNPNMHOP_00066 8.6e-173 2.7.1.2 GK ROK family
CNPNMHOP_00067 0.0 G Glycosyl hydrolase family 20, domain 2
CNPNMHOP_00068 7.6e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CNPNMHOP_00069 4.3e-234 nagA 3.5.1.25 G Amidohydrolase family
CNPNMHOP_00070 2.3e-187 lacR K Transcriptional regulator, LacI family
CNPNMHOP_00071 0.0 T Diguanylate cyclase, GGDEF domain
CNPNMHOP_00072 5.5e-250 3.2.1.14 GH18 S Carbohydrate binding domain
CNPNMHOP_00073 0.0 M probably involved in cell wall
CNPNMHOP_00074 2.9e-234 M Protein of unknown function (DUF2961)
CNPNMHOP_00075 7.4e-144 I alpha/beta hydrolase fold
CNPNMHOP_00076 1.3e-152 S AAA domain
CNPNMHOP_00077 6.9e-206 lipA I Hydrolase, alpha beta domain protein
CNPNMHOP_00078 1.2e-140 mdlA2 V ABC transporter
CNPNMHOP_00079 0.0 tetP J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNPNMHOP_00080 3e-183 mdlA2 V ABC transporter
CNPNMHOP_00081 0.0 yknV V ABC transporter
CNPNMHOP_00082 8e-126
CNPNMHOP_00083 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_00084 1.4e-223 K helix_turn _helix lactose operon repressor
CNPNMHOP_00085 1.1e-232 G Alpha galactosidase A
CNPNMHOP_00086 0.0 G Alpha-L-arabinofuranosidase C-terminus
CNPNMHOP_00087 8.5e-184 tatD L TatD related DNase
CNPNMHOP_00088 0.0 kup P Transport of potassium into the cell
CNPNMHOP_00089 1e-167 S Glutamine amidotransferase domain
CNPNMHOP_00090 5.1e-150 T HD domain
CNPNMHOP_00091 2.2e-157 V ABC transporter
CNPNMHOP_00092 2.8e-241 V ABC transporter permease
CNPNMHOP_00093 0.0 S Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_00094 2.8e-246 S zinc finger
CNPNMHOP_00095 2e-71 S Bacterial PH domain
CNPNMHOP_00096 1.5e-76
CNPNMHOP_00097 1.4e-200 V Domain of unknown function (DUF3427)
CNPNMHOP_00098 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
CNPNMHOP_00099 5.8e-183 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
CNPNMHOP_00100 5.6e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
CNPNMHOP_00101 1.2e-233 aspB E Aminotransferase class-V
CNPNMHOP_00102 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
CNPNMHOP_00103 1.3e-99 tmp1 S Domain of unknown function (DUF4391)
CNPNMHOP_00104 4.8e-199 S Endonuclease/Exonuclease/phosphatase family
CNPNMHOP_00106 7e-41 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CNPNMHOP_00107 4.4e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CNPNMHOP_00108 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
CNPNMHOP_00109 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CNPNMHOP_00110 3.9e-156 hgdC I BadF/BadG/BcrA/BcrD ATPase family
CNPNMHOP_00111 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
CNPNMHOP_00112 3.9e-253 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
CNPNMHOP_00113 1.1e-115 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00114 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
CNPNMHOP_00115 2.5e-107 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00116 5.8e-239 G Transporter major facilitator family protein
CNPNMHOP_00117 2.3e-234 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNPNMHOP_00118 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
CNPNMHOP_00119 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
CNPNMHOP_00120 2.3e-108 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00121 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
CNPNMHOP_00122 3.4e-219 lmrB U Major Facilitator Superfamily
CNPNMHOP_00123 2.6e-15 K helix_turn_helix, mercury resistance
CNPNMHOP_00124 2.9e-87 K Periplasmic binding protein domain
CNPNMHOP_00125 3.2e-151 EGP Major facilitator Superfamily
CNPNMHOP_00126 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
CNPNMHOP_00127 5.4e-181 G Transporter major facilitator family protein
CNPNMHOP_00128 2.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CNPNMHOP_00129 5.1e-107 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00130 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
CNPNMHOP_00131 3.2e-98 K MarR family
CNPNMHOP_00132 0.0 V ABC transporter, ATP-binding protein
CNPNMHOP_00133 0.0 V ABC transporter transmembrane region
CNPNMHOP_00134 1.1e-184 lacR K Transcriptional regulator, LacI family
CNPNMHOP_00135 3e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
CNPNMHOP_00136 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CNPNMHOP_00137 1.1e-104
CNPNMHOP_00138 1.1e-216 cas3 L CRISPR-associated helicase Cas3
CNPNMHOP_00139 1.4e-94
CNPNMHOP_00140 3.6e-256 cas4 3.1.12.1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CNPNMHOP_00141 2.5e-25 cas2 L CRISPR associated protein Cas2
CNPNMHOP_00142 1.8e-85
CNPNMHOP_00143 8.9e-127 S Phospholipase/Carboxylesterase
CNPNMHOP_00144 8.1e-240 patB 4.4.1.8 E Aminotransferase, class I II
CNPNMHOP_00145 6.7e-187 K LysR substrate binding domain protein
CNPNMHOP_00146 6.1e-154 S Patatin-like phospholipase
CNPNMHOP_00147 6.4e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
CNPNMHOP_00148 6e-302 E ABC transporter, substrate-binding protein, family 5
CNPNMHOP_00149 3e-20 S Patatin-like phospholipase
CNPNMHOP_00150 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CNPNMHOP_00151 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
CNPNMHOP_00152 4.8e-117 S Vitamin K epoxide reductase
CNPNMHOP_00153 2.9e-173 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
CNPNMHOP_00154 3.6e-32 S Protein of unknown function (DUF3107)
CNPNMHOP_00155 1.5e-267 mphA S Aminoglycoside phosphotransferase
CNPNMHOP_00156 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
CNPNMHOP_00157 1.7e-285 S Zincin-like metallopeptidase
CNPNMHOP_00158 1.3e-154 lon T Belongs to the peptidase S16 family
CNPNMHOP_00159 6.5e-75 S Protein of unknown function (DUF3052)
CNPNMHOP_00161 4e-239 2.7.11.1 NU Tfp pilus assembly protein FimV
CNPNMHOP_00162 8.5e-218 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CNPNMHOP_00163 5.6e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CNPNMHOP_00164 0.0 I acetylesterase activity
CNPNMHOP_00165 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
CNPNMHOP_00166 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CNPNMHOP_00167 1.2e-217 iunH1 3.2.2.1 F nucleoside hydrolase
CNPNMHOP_00168 5.3e-206 P NMT1/THI5 like
CNPNMHOP_00169 5.5e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00170 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
CNPNMHOP_00171 4e-240 lacY P LacY proton/sugar symporter
CNPNMHOP_00172 1.1e-192 K helix_turn _helix lactose operon repressor
CNPNMHOP_00173 3e-60 S Thiamine-binding protein
CNPNMHOP_00174 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CNPNMHOP_00175 2e-132 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CNPNMHOP_00176 9.9e-155 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CNPNMHOP_00177 0.0
CNPNMHOP_00178 0.0 pilT NU Type II/IV secretion system protein
CNPNMHOP_00179 0.0 pulE NU Type II/IV secretion system protein
CNPNMHOP_00180 1.4e-136 ppdC NU Prokaryotic N-terminal methylation motif
CNPNMHOP_00181 1.6e-104 S Prokaryotic N-terminal methylation motif
CNPNMHOP_00182 1.8e-40 pilA NU Prokaryotic N-terminal methylation motif
CNPNMHOP_00183 7.7e-231 pilC U Type II secretion system (T2SS), protein F
CNPNMHOP_00184 0.0
CNPNMHOP_00185 2.4e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
CNPNMHOP_00186 1.1e-189 pilM NU Type IV pilus assembly protein PilM;
CNPNMHOP_00187 1.8e-165 pilN NU PFAM Fimbrial assembly family protein
CNPNMHOP_00188 1e-105 S Pilus assembly protein, PilO
CNPNMHOP_00189 1.3e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
CNPNMHOP_00190 2.1e-243 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CNPNMHOP_00191 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CNPNMHOP_00192 1.5e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CNPNMHOP_00193 3.4e-40 yggT S YGGT family
CNPNMHOP_00194 1.3e-30 3.1.21.3 V DivIVA protein
CNPNMHOP_00195 3.6e-86 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CNPNMHOP_00196 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CNPNMHOP_00197 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
CNPNMHOP_00198 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CNPNMHOP_00199 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CNPNMHOP_00200 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
CNPNMHOP_00201 1.5e-122
CNPNMHOP_00202 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CNPNMHOP_00203 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
CNPNMHOP_00204 3.1e-264 glnA2 6.3.1.2 E glutamine synthetase
CNPNMHOP_00205 3.1e-217 S Domain of unknown function (DUF5067)
CNPNMHOP_00206 9e-138 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
CNPNMHOP_00207 5.2e-218 EGP Major facilitator Superfamily
CNPNMHOP_00208 4.2e-118 ytrE V ATPases associated with a variety of cellular activities
CNPNMHOP_00209 1.4e-90
CNPNMHOP_00210 7.2e-156 V N-Acetylmuramoyl-L-alanine amidase
CNPNMHOP_00211 1.7e-185
CNPNMHOP_00212 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
CNPNMHOP_00213 5.9e-114 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
CNPNMHOP_00214 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNPNMHOP_00215 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
CNPNMHOP_00216 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CNPNMHOP_00217 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CNPNMHOP_00218 1e-53 M Lysin motif
CNPNMHOP_00219 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNPNMHOP_00220 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
CNPNMHOP_00221 0.0 L DNA helicase
CNPNMHOP_00222 7e-92 mraZ K Belongs to the MraZ family
CNPNMHOP_00223 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CNPNMHOP_00224 6.7e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CNPNMHOP_00225 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
CNPNMHOP_00226 1.1e-153 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNPNMHOP_00227 6.4e-263 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CNPNMHOP_00228 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNPNMHOP_00229 6.2e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CNPNMHOP_00230 8.1e-203 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
CNPNMHOP_00231 1.8e-215 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CNPNMHOP_00232 2.3e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
CNPNMHOP_00233 4.6e-141 ftsQ 6.3.2.4 D Cell division protein FtsQ
CNPNMHOP_00234 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
CNPNMHOP_00235 1.6e-27
CNPNMHOP_00236 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
CNPNMHOP_00237 1.1e-164 2.7.1.4 G pfkB family carbohydrate kinase
CNPNMHOP_00238 1.7e-218 GK ROK family
CNPNMHOP_00239 6.1e-307 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
CNPNMHOP_00240 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00241 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00242 0.0 P Belongs to the ABC transporter superfamily
CNPNMHOP_00243 9.9e-94 3.6.1.55 F NUDIX domain
CNPNMHOP_00244 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
CNPNMHOP_00245 2.6e-273 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
CNPNMHOP_00246 5e-187 V Acetyltransferase (GNAT) domain
CNPNMHOP_00247 7.1e-281 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CNPNMHOP_00248 7.4e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
CNPNMHOP_00249 1.2e-36
CNPNMHOP_00250 4.3e-188 galM 5.1.3.3 G Aldose 1-epimerase
CNPNMHOP_00251 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CNPNMHOP_00252 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CNPNMHOP_00253 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CNPNMHOP_00254 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
CNPNMHOP_00255 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNPNMHOP_00256 2.1e-25 rpmI J Ribosomal protein L35
CNPNMHOP_00257 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CNPNMHOP_00258 2e-177 xerD D recombinase XerD
CNPNMHOP_00259 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
CNPNMHOP_00260 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
CNPNMHOP_00261 1.7e-249 naiP U Sugar (and other) transporter
CNPNMHOP_00262 0.0 typA T Elongation factor G C-terminus
CNPNMHOP_00263 4e-104
CNPNMHOP_00264 3.7e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
CNPNMHOP_00265 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
CNPNMHOP_00266 2.8e-34
CNPNMHOP_00267 5.2e-08
CNPNMHOP_00268 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
CNPNMHOP_00269 0.0 E ABC transporter, substrate-binding protein, family 5
CNPNMHOP_00270 0.0 E ABC transporter, substrate-binding protein, family 5
CNPNMHOP_00271 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00272 1.4e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
CNPNMHOP_00273 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
CNPNMHOP_00274 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
CNPNMHOP_00275 1.7e-151 S Protein of unknown function (DUF3710)
CNPNMHOP_00276 2.4e-133 S Protein of unknown function (DUF3159)
CNPNMHOP_00277 1.4e-237 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CNPNMHOP_00278 2.3e-70
CNPNMHOP_00279 0.0 ctpE P E1-E2 ATPase
CNPNMHOP_00280 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CNPNMHOP_00281 1.4e-248 VP1224 V Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_00282 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
CNPNMHOP_00283 9.8e-213 rhaR1 K helix_turn_helix, arabinose operon control protein
CNPNMHOP_00284 1.1e-229 V ABC-2 family transporter protein
CNPNMHOP_00285 2.2e-224 V ABC-2 family transporter protein
CNPNMHOP_00286 4.4e-191 V ATPases associated with a variety of cellular activities
CNPNMHOP_00287 1.8e-243 T Histidine kinase
CNPNMHOP_00288 9e-116 K helix_turn_helix, Lux Regulon
CNPNMHOP_00289 0.0 S Protein of unknown function DUF262
CNPNMHOP_00290 1.8e-127 K helix_turn_helix, Lux Regulon
CNPNMHOP_00291 3.3e-242 T Histidine kinase
CNPNMHOP_00292 1.4e-57 S Domain of unknown function (DUF5067)
CNPNMHOP_00293 1.7e-127 ybhL S Belongs to the BI1 family
CNPNMHOP_00294 8e-177 ydeD EG EamA-like transporter family
CNPNMHOP_00295 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
CNPNMHOP_00296 8.7e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CNPNMHOP_00297 6e-191 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNPNMHOP_00298 7.2e-11 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CNPNMHOP_00299 0.0 ftsK D FtsK SpoIIIE family protein
CNPNMHOP_00300 8.6e-122 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNPNMHOP_00301 1e-96 cinA 3.5.1.42 S Belongs to the CinA family
CNPNMHOP_00302 2.3e-79 K Helix-turn-helix XRE-family like proteins
CNPNMHOP_00303 8.2e-45 S Protein of unknown function (DUF3046)
CNPNMHOP_00304 2.3e-207 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CNPNMHOP_00305 1.1e-119 recX S Modulates RecA activity
CNPNMHOP_00306 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CNPNMHOP_00307 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CNPNMHOP_00308 6.5e-193 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNPNMHOP_00309 1.1e-96
CNPNMHOP_00310 1.5e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
CNPNMHOP_00311 0.0 pknL 2.7.11.1 KLT PASTA
CNPNMHOP_00312 1.4e-195 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
CNPNMHOP_00313 1.1e-118
CNPNMHOP_00314 3.4e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CNPNMHOP_00315 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
CNPNMHOP_00316 1.5e-222 G Major Facilitator Superfamily
CNPNMHOP_00317 1.2e-239 T PhoQ Sensor
CNPNMHOP_00318 2.4e-79 S Protein of unknown function (DUF2975)
CNPNMHOP_00319 5.8e-32 yozG K Cro/C1-type HTH DNA-binding domain
CNPNMHOP_00320 0.0 lhr L DEAD DEAH box helicase
CNPNMHOP_00321 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
CNPNMHOP_00322 3e-234 S Type I phosphodiesterase / nucleotide pyrophosphatase
CNPNMHOP_00323 7e-147 S Protein of unknown function (DUF3071)
CNPNMHOP_00324 1e-47 S Domain of unknown function (DUF4193)
CNPNMHOP_00325 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CNPNMHOP_00326 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNPNMHOP_00327 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CNPNMHOP_00328 2.9e-236 dinF V MatE
CNPNMHOP_00329 0.0 S LPXTG-motif cell wall anchor domain protein
CNPNMHOP_00331 1.3e-52 L Helix-turn-helix domain
CNPNMHOP_00332 1.8e-101 V Abi-like protein
CNPNMHOP_00333 3.9e-16 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00334 1.1e-74
CNPNMHOP_00335 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00336 5.5e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNPNMHOP_00337 5.3e-145 metQ P NLPA lipoprotein
CNPNMHOP_00338 1.7e-156 S Sucrose-6F-phosphate phosphohydrolase
CNPNMHOP_00339 1.8e-225 S Peptidase dimerisation domain
CNPNMHOP_00340 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNPNMHOP_00341 4.5e-31
CNPNMHOP_00342 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
CNPNMHOP_00343 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CNPNMHOP_00344 9.9e-80 S Protein of unknown function (DUF3000)
CNPNMHOP_00345 3.3e-239 rnd 3.1.13.5 J 3'-5' exonuclease
CNPNMHOP_00346 2.7e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CNPNMHOP_00347 1.9e-130 yebE S DUF218 domain
CNPNMHOP_00348 7.6e-129 E Psort location Cytoplasmic, score 8.87
CNPNMHOP_00349 3.9e-159 O Thioredoxin
CNPNMHOP_00350 1.2e-158 msbA2 3.6.3.44 V ABC transporter transmembrane region
CNPNMHOP_00351 1.5e-208 KLT Lanthionine synthetase C-like protein
CNPNMHOP_00352 1.9e-113 K helix_turn_helix, Lux Regulon
CNPNMHOP_00353 4.8e-136 2.7.13.3 T Histidine kinase
CNPNMHOP_00355 1.3e-42 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CNPNMHOP_00356 4.4e-117 S phosphoesterase or phosphohydrolase
CNPNMHOP_00357 2.6e-118
CNPNMHOP_00358 1.5e-69
CNPNMHOP_00359 3.2e-22
CNPNMHOP_00360 3.7e-65 S Putative inner membrane protein (DUF1819)
CNPNMHOP_00361 1.6e-41 lexA 3.6.4.12 K Putative DNA-binding domain
CNPNMHOP_00362 2.6e-131 XK26_04895
CNPNMHOP_00363 0.0 KL Type III restriction enzyme res subunit
CNPNMHOP_00364 2.9e-187 L Eco57I restriction-modification methylase
CNPNMHOP_00365 3.9e-184 3.1.21.4 V Type III restriction enzyme res subunit
CNPNMHOP_00366 5.5e-56 S SIR2-like domain
CNPNMHOP_00367 8.5e-252 S AAA-like domain
CNPNMHOP_00368 0.0 S Protein of unknown function DUF262
CNPNMHOP_00369 4.9e-33 S Protein of unknown function DUF262
CNPNMHOP_00371 1.2e-123 3.2.1.8 S alpha beta
CNPNMHOP_00372 5.9e-85 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CNPNMHOP_00373 1.3e-182 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
CNPNMHOP_00374 1.8e-112 kcsA U Ion channel
CNPNMHOP_00375 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
CNPNMHOP_00376 2.3e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CNPNMHOP_00377 0.0 ecfA GP ABC transporter, ATP-binding protein
CNPNMHOP_00378 2.4e-47 yhbY J CRS1_YhbY
CNPNMHOP_00379 9.6e-146 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CNPNMHOP_00380 2.2e-201 S Glycosyltransferase, group 2 family protein
CNPNMHOP_00381 2.7e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
CNPNMHOP_00382 8.1e-221 E Aminotransferase class I and II
CNPNMHOP_00383 1.1e-144 bioM P ATPases associated with a variety of cellular activities
CNPNMHOP_00384 1.2e-305 2.8.2.22 S Arylsulfotransferase Ig-like domain
CNPNMHOP_00385 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNPNMHOP_00386 0.0 S Tetratricopeptide repeat
CNPNMHOP_00387 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CNPNMHOP_00388 8.2e-213 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CNPNMHOP_00389 3.8e-84 ykoE S ABC-type cobalt transport system, permease component
CNPNMHOP_00390 6.7e-268 ykoD P ATPases associated with a variety of cellular activities
CNPNMHOP_00391 3.1e-145 cbiQ P Cobalt transport protein
CNPNMHOP_00392 2.3e-251 argE E Peptidase dimerisation domain
CNPNMHOP_00393 3.6e-93 S Protein of unknown function (DUF3043)
CNPNMHOP_00394 5.4e-246 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNPNMHOP_00395 3.9e-142 S Domain of unknown function (DUF4191)
CNPNMHOP_00396 2.3e-281 glnA 6.3.1.2 E glutamine synthetase
CNPNMHOP_00397 4e-42 V DNA modification
CNPNMHOP_00398 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
CNPNMHOP_00399 1.5e-17 L HNH endonuclease
CNPNMHOP_00401 2.9e-17
CNPNMHOP_00403 2.7e-94 yvdD 3.2.2.10 S Possible lysine decarboxylase
CNPNMHOP_00405 5.9e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CNPNMHOP_00406 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
CNPNMHOP_00407 4.9e-99
CNPNMHOP_00408 4.5e-205 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CNPNMHOP_00409 6.7e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CNPNMHOP_00410 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CNPNMHOP_00411 2.7e-241 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
CNPNMHOP_00412 4.6e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CNPNMHOP_00413 2.3e-82 argR K Regulates arginine biosynthesis genes
CNPNMHOP_00414 4.6e-238 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CNPNMHOP_00415 1.3e-279 argH 4.3.2.1 E argininosuccinate lyase
CNPNMHOP_00416 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
CNPNMHOP_00417 8.6e-137 S Putative ABC-transporter type IV
CNPNMHOP_00418 0.0 S Protein of unknown function (DUF975)
CNPNMHOP_00419 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CNPNMHOP_00420 1.5e-149 L Tetratricopeptide repeat
CNPNMHOP_00421 1.2e-191 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CNPNMHOP_00422 1.9e-133 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CNPNMHOP_00423 3e-116 trkA P TrkA-N domain
CNPNMHOP_00424 2.2e-263 trkB P Cation transport protein
CNPNMHOP_00425 2e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CNPNMHOP_00426 5.3e-261 recN L May be involved in recombinational repair of damaged DNA
CNPNMHOP_00427 2.7e-120 S Haloacid dehalogenase-like hydrolase
CNPNMHOP_00428 1.3e-115 S ABC-2 family transporter protein
CNPNMHOP_00429 2.3e-173 V ATPases associated with a variety of cellular activities
CNPNMHOP_00430 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
CNPNMHOP_00431 1.1e-23 C Acetamidase/Formamidase family
CNPNMHOP_00432 1.6e-44 L transposition
CNPNMHOP_00433 0.0 S Histidine phosphatase superfamily (branch 2)
CNPNMHOP_00434 1.7e-94 S Pyridoxamine 5'-phosphate oxidase
CNPNMHOP_00435 2.6e-22 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00436 6.4e-96 bcp 1.11.1.15 O Redoxin
CNPNMHOP_00438 7.4e-77 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNPNMHOP_00439 1.5e-161 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNPNMHOP_00440 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
CNPNMHOP_00441 2e-142
CNPNMHOP_00442 7.4e-174 G Fic/DOC family
CNPNMHOP_00443 4.7e-105 3.1.3.27 E haloacid dehalogenase-like hydrolase
CNPNMHOP_00444 4.4e-231 EGP Major facilitator Superfamily
CNPNMHOP_00445 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
CNPNMHOP_00446 1.4e-250 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CNPNMHOP_00447 1.9e-242 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CNPNMHOP_00448 3.2e-101
CNPNMHOP_00449 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNPNMHOP_00450 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNPNMHOP_00452 1.8e-121
CNPNMHOP_00453 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
CNPNMHOP_00454 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CNPNMHOP_00455 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
CNPNMHOP_00456 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CNPNMHOP_00458 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CNPNMHOP_00459 7.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CNPNMHOP_00460 2.3e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
CNPNMHOP_00461 3.2e-225 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CNPNMHOP_00462 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CNPNMHOP_00463 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CNPNMHOP_00464 7.1e-297 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CNPNMHOP_00465 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CNPNMHOP_00466 2.6e-163 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CNPNMHOP_00467 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CNPNMHOP_00468 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
CNPNMHOP_00469 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
CNPNMHOP_00470 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
CNPNMHOP_00471 1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNPNMHOP_00472 2.6e-172 S Bacterial protein of unknown function (DUF881)
CNPNMHOP_00473 4.2e-45 sbp S Protein of unknown function (DUF1290)
CNPNMHOP_00474 1.6e-141 S Bacterial protein of unknown function (DUF881)
CNPNMHOP_00475 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CNPNMHOP_00476 3.5e-112 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
CNPNMHOP_00477 5.2e-128 yebC K transcriptional regulatory protein
CNPNMHOP_00478 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
CNPNMHOP_00479 5.1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CNPNMHOP_00480 5.6e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CNPNMHOP_00481 1e-58 yajC U Preprotein translocase subunit
CNPNMHOP_00482 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CNPNMHOP_00483 2.2e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CNPNMHOP_00484 2.6e-161 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CNPNMHOP_00485 1.8e-246
CNPNMHOP_00486 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CNPNMHOP_00487 8.2e-34
CNPNMHOP_00488 4.9e-160 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
CNPNMHOP_00489 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CNPNMHOP_00490 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
CNPNMHOP_00491 1.1e-69
CNPNMHOP_00493 3.7e-265 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
CNPNMHOP_00494 0.0 pafB K WYL domain
CNPNMHOP_00495 2.1e-54
CNPNMHOP_00496 0.0 helY L DEAD DEAH box helicase
CNPNMHOP_00497 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
CNPNMHOP_00498 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
CNPNMHOP_00499 4.6e-61
CNPNMHOP_00500 9.7e-112 K helix_turn_helix, mercury resistance
CNPNMHOP_00501 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
CNPNMHOP_00502 9.4e-36
CNPNMHOP_00507 1.6e-156 S PAC2 family
CNPNMHOP_00508 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CNPNMHOP_00509 5.1e-158 G Fructosamine kinase
CNPNMHOP_00510 3.2e-117 L Phage integrase family
CNPNMHOP_00511 5.5e-151 XK27_00240 K Fic/DOC family
CNPNMHOP_00513 2e-38
CNPNMHOP_00514 1.5e-24
CNPNMHOP_00518 1.7e-81 K BRO family, N-terminal domain
CNPNMHOP_00520 4.4e-41 O prohibitin homologues
CNPNMHOP_00524 1.7e-110 yqaJ L YqaJ-like viral recombinase domain
CNPNMHOP_00525 1.6e-84 recT L RecT family
CNPNMHOP_00527 5.3e-66
CNPNMHOP_00528 1e-60 L HNH endonuclease
CNPNMHOP_00529 3.1e-20
CNPNMHOP_00530 4.8e-11
CNPNMHOP_00531 2.5e-27
CNPNMHOP_00533 2e-46
CNPNMHOP_00537 6.5e-12
CNPNMHOP_00539 2.8e-92
CNPNMHOP_00543 8.6e-40 L HNH nucleases
CNPNMHOP_00545 4.8e-10
CNPNMHOP_00546 4.5e-222 S Terminase
CNPNMHOP_00547 2.1e-69 S Phage portal protein
CNPNMHOP_00548 7.1e-32 xkdG S Phage capsid family
CNPNMHOP_00549 1.5e-89 xkdG S Phage capsid family
CNPNMHOP_00550 8.7e-21
CNPNMHOP_00551 1.1e-30
CNPNMHOP_00552 3.4e-27
CNPNMHOP_00553 1.7e-27
CNPNMHOP_00554 2.1e-55
CNPNMHOP_00555 6.5e-27
CNPNMHOP_00557 6.4e-38 NT phage tail tape measure protein
CNPNMHOP_00558 9.9e-22 NT phage tail tape measure protein
CNPNMHOP_00559 3.8e-42
CNPNMHOP_00560 1.2e-79 S Psort location Cytoplasmic, score
CNPNMHOP_00562 2.8e-22 V Type II restriction enzyme, methylase subunits
CNPNMHOP_00563 3.3e-155 ksgA 2.1.1.182, 2.1.1.184 J Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family
CNPNMHOP_00564 2.9e-24 L transposase activity
CNPNMHOP_00565 9.3e-108 L Transposase and inactivated derivatives
CNPNMHOP_00566 4.3e-55 KLT Protein tyrosine kinase
CNPNMHOP_00567 2.5e-259 EGP Transmembrane secretion effector
CNPNMHOP_00568 4.3e-147 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00569 9.1e-168 G ABC transporter permease
CNPNMHOP_00572 3.9e-131 clcA P Voltage gated chloride channel
CNPNMHOP_00573 1.1e-138 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNPNMHOP_00574 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNPNMHOP_00575 4.1e-29 E Receptor family ligand binding region
CNPNMHOP_00576 1e-196 K helix_turn _helix lactose operon repressor
CNPNMHOP_00577 6.5e-295 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
CNPNMHOP_00578 4.9e-10 S Protein of unknown function, DUF624
CNPNMHOP_00579 2e-278 scrT G Transporter major facilitator family protein
CNPNMHOP_00580 7.9e-252 yhjE EGP Sugar (and other) transporter
CNPNMHOP_00581 2e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNPNMHOP_00582 4e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CNPNMHOP_00583 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
CNPNMHOP_00584 2.6e-35 G beta-mannosidase
CNPNMHOP_00585 3.1e-187 K helix_turn _helix lactose operon repressor
CNPNMHOP_00586 4.4e-13 S Protein of unknown function, DUF624
CNPNMHOP_00587 3.5e-269 aroP E aromatic amino acid transport protein AroP K03293
CNPNMHOP_00588 0.0 V FtsX-like permease family
CNPNMHOP_00589 3.3e-227 P Sodium/hydrogen exchanger family
CNPNMHOP_00590 1.3e-76 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00591 3.6e-178 3.4.22.70 M Sortase family
CNPNMHOP_00592 0.0 inlJ M domain protein
CNPNMHOP_00593 1.3e-181 M LPXTG cell wall anchor motif
CNPNMHOP_00594 2.5e-89 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00595 9.9e-275 cycA E Amino acid permease
CNPNMHOP_00596 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CNPNMHOP_00597 3.8e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
CNPNMHOP_00598 3.8e-26 thiS 2.8.1.10 H ThiS family
CNPNMHOP_00599 8.5e-185 1.1.1.65 C Aldo/keto reductase family
CNPNMHOP_00600 1.6e-56 ydgJ K helix_turn_helix multiple antibiotic resistance protein
CNPNMHOP_00601 1e-284 lmrA1 V ABC transporter, ATP-binding protein
CNPNMHOP_00602 0.0 lmrA2 V ABC transporter transmembrane region
CNPNMHOP_00603 1.7e-115 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CNPNMHOP_00604 1.2e-237 G MFS/sugar transport protein
CNPNMHOP_00605 2.1e-297 efeU_1 P Iron permease FTR1 family
CNPNMHOP_00606 2.4e-92 tpd P Fe2+ transport protein
CNPNMHOP_00607 5.2e-229 S Predicted membrane protein (DUF2318)
CNPNMHOP_00608 2.3e-219 macB_2 V ABC transporter permease
CNPNMHOP_00610 4.5e-201 Z012_06715 V FtsX-like permease family
CNPNMHOP_00611 9e-150 macB V ABC transporter, ATP-binding protein
CNPNMHOP_00612 1.1e-61 S FMN_bind
CNPNMHOP_00613 2.7e-88 K Psort location Cytoplasmic, score 8.87
CNPNMHOP_00614 1.8e-274 pip S YhgE Pip domain protein
CNPNMHOP_00615 0.0 pip S YhgE Pip domain protein
CNPNMHOP_00616 6.3e-227 S Putative ABC-transporter type IV
CNPNMHOP_00617 1.7e-37 nrdH O Glutaredoxin
CNPNMHOP_00618 2.1e-73 M cell wall organization
CNPNMHOP_00619 7.9e-18
CNPNMHOP_00621 1.6e-307 pepD E Peptidase family C69
CNPNMHOP_00622 8.3e-193 XK27_01805 M Glycosyltransferase like family 2
CNPNMHOP_00624 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
CNPNMHOP_00625 1.9e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CNPNMHOP_00626 1.5e-236 amt U Ammonium Transporter Family
CNPNMHOP_00627 7.7e-55 glnB K Nitrogen regulatory protein P-II
CNPNMHOP_00628 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
CNPNMHOP_00629 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CNPNMHOP_00630 6e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
CNPNMHOP_00631 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
CNPNMHOP_00632 1e-27 S granule-associated protein
CNPNMHOP_00633 0.0 ubiB S ABC1 family
CNPNMHOP_00634 1.4e-192 K Periplasmic binding protein domain
CNPNMHOP_00635 2.5e-242 G Bacterial extracellular solute-binding protein
CNPNMHOP_00636 3.1e-167 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00637 9.3e-147 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00638 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
CNPNMHOP_00639 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
CNPNMHOP_00640 0.0 G Bacterial Ig-like domain (group 4)
CNPNMHOP_00641 1.8e-206 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
CNPNMHOP_00642 2.7e-117 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CNPNMHOP_00643 3.9e-91
CNPNMHOP_00644 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
CNPNMHOP_00645 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CNPNMHOP_00647 1.1e-141 cpaE D bacterial-type flagellum organization
CNPNMHOP_00648 1.6e-185 cpaF U Type II IV secretion system protein
CNPNMHOP_00649 6.2e-123 U Type ii secretion system
CNPNMHOP_00650 1.4e-87 gspF NU Type II secretion system (T2SS), protein F
CNPNMHOP_00651 1.3e-42 S Protein of unknown function (DUF4244)
CNPNMHOP_00652 5.1e-60 U TadE-like protein
CNPNMHOP_00653 4.7e-56 S TIGRFAM helicase secretion neighborhood TadE-like protein
CNPNMHOP_00654 1.6e-216 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
CNPNMHOP_00655 1.6e-193 S Psort location CytoplasmicMembrane, score
CNPNMHOP_00656 1.1e-96 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00657 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
CNPNMHOP_00658 7.7e-106 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CNPNMHOP_00659 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
CNPNMHOP_00660 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
CNPNMHOP_00661 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CNPNMHOP_00662 2.7e-48 yitI S Acetyltransferase (GNAT) domain
CNPNMHOP_00663 2.4e-115
CNPNMHOP_00664 2.1e-299 S Calcineurin-like phosphoesterase
CNPNMHOP_00665 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CNPNMHOP_00666 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
CNPNMHOP_00667 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
CNPNMHOP_00668 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
CNPNMHOP_00669 1.1e-195 K helix_turn _helix lactose operon repressor
CNPNMHOP_00670 1.3e-203 abf G Glycosyl hydrolases family 43
CNPNMHOP_00671 2.7e-244 G Bacterial extracellular solute-binding protein
CNPNMHOP_00672 5e-168 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00673 4.6e-155 U Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00674 0.0 S Beta-L-arabinofuranosidase, GH127
CNPNMHOP_00675 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
CNPNMHOP_00676 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
CNPNMHOP_00677 1.3e-234 glf 5.4.99.9 M UDP-galactopyranose mutase
CNPNMHOP_00678 2.4e-190 3.6.1.27 I PAP2 superfamily
CNPNMHOP_00679 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNPNMHOP_00680 1.2e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CNPNMHOP_00681 2.7e-192 holB 2.7.7.7 L DNA polymerase III
CNPNMHOP_00682 3.7e-185 K helix_turn _helix lactose operon repressor
CNPNMHOP_00683 6e-39 ptsH G PTS HPr component phosphorylation site
CNPNMHOP_00684 4.6e-286 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNPNMHOP_00685 1.1e-106 S Phosphatidylethanolamine-binding protein
CNPNMHOP_00686 0.0 pepD E Peptidase family C69
CNPNMHOP_00687 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
CNPNMHOP_00688 6.7e-62 S Macrophage migration inhibitory factor (MIF)
CNPNMHOP_00689 7.1e-95 S GtrA-like protein
CNPNMHOP_00690 2.1e-263 EGP Major facilitator Superfamily
CNPNMHOP_00691 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
CNPNMHOP_00692 7e-184
CNPNMHOP_00693 3e-91 S Protein of unknown function (DUF805)
CNPNMHOP_00694 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CNPNMHOP_00697 3e-268 S Calcineurin-like phosphoesterase
CNPNMHOP_00698 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
CNPNMHOP_00699 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CNPNMHOP_00700 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CNPNMHOP_00701 1.4e-199 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
CNPNMHOP_00702 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CNPNMHOP_00703 7.2e-177 plsC2 2.3.1.51 I Phosphate acyltransferases
CNPNMHOP_00704 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
CNPNMHOP_00705 9.8e-219 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CNPNMHOP_00706 2.9e-175 S CAAX protease self-immunity
CNPNMHOP_00707 1.7e-137 M Mechanosensitive ion channel
CNPNMHOP_00708 5e-229 MA20_36090 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00709 2.1e-227 MA20_36090 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00710 2e-121 K Bacterial regulatory proteins, tetR family
CNPNMHOP_00711 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
CNPNMHOP_00712 5.2e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
CNPNMHOP_00713 6e-228 gnuT EG GntP family permease
CNPNMHOP_00714 1.9e-82 gntK 2.7.1.12 F Shikimate kinase
CNPNMHOP_00715 1.9e-127 gntR K FCD
CNPNMHOP_00716 1.4e-229 yxiO S Vacuole effluxer Atg22 like
CNPNMHOP_00717 0.0 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_00718 8.4e-30 rpmB J Ribosomal L28 family
CNPNMHOP_00719 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
CNPNMHOP_00720 6.5e-105 rsmD 2.1.1.171 L Conserved hypothetical protein 95
CNPNMHOP_00721 3.2e-151 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CNPNMHOP_00722 3.6e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CNPNMHOP_00723 1.8e-34 CP_0960 S Belongs to the UPF0109 family
CNPNMHOP_00724 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CNPNMHOP_00725 3.7e-177 S Endonuclease/Exonuclease/phosphatase family
CNPNMHOP_00726 8.4e-272 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CNPNMHOP_00727 2.1e-302 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
CNPNMHOP_00728 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
CNPNMHOP_00729 0.0 yjjK S ABC transporter
CNPNMHOP_00730 1.2e-94
CNPNMHOP_00732 5.3e-245 S Domain of unknown function (DUF4143)
CNPNMHOP_00733 5.7e-92 ilvN 2.2.1.6 E ACT domain
CNPNMHOP_00734 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
CNPNMHOP_00735 1.7e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CNPNMHOP_00736 1.7e-22 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CNPNMHOP_00737 1.8e-113 yceD S Uncharacterized ACR, COG1399
CNPNMHOP_00738 1.1e-130
CNPNMHOP_00739 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CNPNMHOP_00740 3.2e-58 S Protein of unknown function (DUF3039)
CNPNMHOP_00741 1.7e-195 yghZ C Aldo/keto reductase family
CNPNMHOP_00742 9.2e-77 soxR K MerR, DNA binding
CNPNMHOP_00743 2.3e-119 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CNPNMHOP_00744 1.9e-138 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CNPNMHOP_00745 5e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CNPNMHOP_00746 2.1e-238 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
CNPNMHOP_00747 2.4e-174 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
CNPNMHOP_00748 1.3e-34 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
CNPNMHOP_00751 1.3e-179 S Auxin Efflux Carrier
CNPNMHOP_00752 0.0 pgi 5.3.1.9 G Belongs to the GPI family
CNPNMHOP_00753 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CNPNMHOP_00754 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CNPNMHOP_00755 2.1e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNPNMHOP_00756 5e-128 V ATPases associated with a variety of cellular activities
CNPNMHOP_00757 1.6e-269 V Efflux ABC transporter, permease protein
CNPNMHOP_00758 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
CNPNMHOP_00759 2.9e-229 dapE 3.5.1.18 E Peptidase dimerisation domain
CNPNMHOP_00760 6.6e-309 rne 3.1.26.12 J Ribonuclease E/G family
CNPNMHOP_00761 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
CNPNMHOP_00762 2.6e-39 rpmA J Ribosomal L27 protein
CNPNMHOP_00763 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CNPNMHOP_00764 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CNPNMHOP_00765 8.2e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
CNPNMHOP_00767 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CNPNMHOP_00768 1.1e-128 nusG K Participates in transcription elongation, termination and antitermination
CNPNMHOP_00769 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CNPNMHOP_00770 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CNPNMHOP_00771 5.9e-143 QT PucR C-terminal helix-turn-helix domain
CNPNMHOP_00772 0.0
CNPNMHOP_00773 3.9e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
CNPNMHOP_00774 9.6e-77 bioY S BioY family
CNPNMHOP_00775 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
CNPNMHOP_00776 0.0 pccB I Carboxyl transferase domain
CNPNMHOP_00777 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
CNPNMHOP_00779 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CNPNMHOP_00780 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
CNPNMHOP_00782 1.4e-116
CNPNMHOP_00783 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CNPNMHOP_00784 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CNPNMHOP_00785 8.5e-91 lemA S LemA family
CNPNMHOP_00786 0.0 S Predicted membrane protein (DUF2207)
CNPNMHOP_00787 3.7e-170 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
CNPNMHOP_00788 7e-297 yegQ O Peptidase family U32 C-terminal domain
CNPNMHOP_00789 4.1e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
CNPNMHOP_00790 7e-150 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CNPNMHOP_00791 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CNPNMHOP_00792 1.3e-58 D nuclear chromosome segregation
CNPNMHOP_00793 2.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
CNPNMHOP_00794 8.2e-210 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNPNMHOP_00795 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNPNMHOP_00796 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CNPNMHOP_00797 2.8e-220 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
CNPNMHOP_00798 3.4e-129 KT Transcriptional regulatory protein, C terminal
CNPNMHOP_00799 1e-196 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
CNPNMHOP_00800 1.3e-163 pstC P probably responsible for the translocation of the substrate across the membrane
CNPNMHOP_00801 1.2e-167 pstA P Phosphate transport system permease
CNPNMHOP_00802 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CNPNMHOP_00803 1.3e-141 P Zinc-uptake complex component A periplasmic
CNPNMHOP_00804 1.3e-246 pbuO S Permease family
CNPNMHOP_00805 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CNPNMHOP_00806 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CNPNMHOP_00807 1.6e-175 T Forkhead associated domain
CNPNMHOP_00808 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
CNPNMHOP_00809 4.8e-36
CNPNMHOP_00810 9.4e-92 flgA NO SAF
CNPNMHOP_00811 6.1e-30 fmdB S Putative regulatory protein
CNPNMHOP_00812 1.4e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
CNPNMHOP_00813 2.9e-122 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
CNPNMHOP_00814 1.6e-147
CNPNMHOP_00815 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CNPNMHOP_00819 5.5e-25 rpmG J Ribosomal protein L33
CNPNMHOP_00820 2.4e-204 murB 1.3.1.98 M Cell wall formation
CNPNMHOP_00821 9.6e-267 E aromatic amino acid transport protein AroP K03293
CNPNMHOP_00822 8.3e-59 fdxA C 4Fe-4S binding domain
CNPNMHOP_00823 7.3e-206 dapC E Aminotransferase class I and II
CNPNMHOP_00825 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
CNPNMHOP_00826 7.7e-180 EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00827 3.9e-141 EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00828 6.7e-156 oppD EP Oligopeptide/dipeptide transporter, C-terminal region
CNPNMHOP_00829 2.8e-151 dppF E ABC transporter
CNPNMHOP_00830 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CNPNMHOP_00831 0.0 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_00832 4.1e-233 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
CNPNMHOP_00833 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
CNPNMHOP_00834 8.7e-297 CE10 I Belongs to the type-B carboxylesterase lipase family
CNPNMHOP_00836 7.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNPNMHOP_00837 1.4e-251 M Bacterial capsule synthesis protein PGA_cap
CNPNMHOP_00838 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CNPNMHOP_00839 2.1e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
CNPNMHOP_00840 6.9e-122
CNPNMHOP_00841 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
CNPNMHOP_00842 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CNPNMHOP_00843 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
CNPNMHOP_00844 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CNPNMHOP_00845 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CNPNMHOP_00846 1.3e-215 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
CNPNMHOP_00847 4.2e-239 EGP Major facilitator Superfamily
CNPNMHOP_00848 3.3e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
CNPNMHOP_00849 5.2e-181 rhaR_1 K helix_turn_helix, arabinose operon control protein
CNPNMHOP_00850 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CNPNMHOP_00851 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
CNPNMHOP_00852 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CNPNMHOP_00853 5.3e-116 rplD J Forms part of the polypeptide exit tunnel
CNPNMHOP_00854 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CNPNMHOP_00855 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CNPNMHOP_00856 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CNPNMHOP_00857 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CNPNMHOP_00858 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CNPNMHOP_00859 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CNPNMHOP_00860 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
CNPNMHOP_00861 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CNPNMHOP_00862 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CNPNMHOP_00863 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CNPNMHOP_00864 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CNPNMHOP_00865 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNPNMHOP_00866 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CNPNMHOP_00867 4.2e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CNPNMHOP_00868 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CNPNMHOP_00869 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CNPNMHOP_00870 3.4e-25 rpmD J Ribosomal protein L30p/L7e
CNPNMHOP_00871 3.7e-73 rplO J binds to the 23S rRNA
CNPNMHOP_00872 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CNPNMHOP_00873 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CNPNMHOP_00874 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CNPNMHOP_00875 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CNPNMHOP_00876 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CNPNMHOP_00877 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CNPNMHOP_00878 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNPNMHOP_00879 1.3e-66 rplQ J Ribosomal protein L17
CNPNMHOP_00880 1.2e-183 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CNPNMHOP_00881 8.1e-43 gcs2 S A circularly permuted ATPgrasp
CNPNMHOP_00882 1.5e-45 E Transglutaminase/protease-like homologues
CNPNMHOP_00884 2.5e-105
CNPNMHOP_00885 6.1e-191 nusA K Participates in both transcription termination and antitermination
CNPNMHOP_00886 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CNPNMHOP_00887 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CNPNMHOP_00888 5.1e-188 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CNPNMHOP_00889 2.6e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
CNPNMHOP_00890 5.9e-250 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CNPNMHOP_00891 5.5e-107
CNPNMHOP_00893 2.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CNPNMHOP_00894 3.9e-213 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNPNMHOP_00895 9.7e-250 T GHKL domain
CNPNMHOP_00896 4e-150 T LytTr DNA-binding domain
CNPNMHOP_00897 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
CNPNMHOP_00898 0.0 crr G pts system, glucose-specific IIABC component
CNPNMHOP_00899 6.4e-154 arbG K CAT RNA binding domain
CNPNMHOP_00900 4.6e-197 I Diacylglycerol kinase catalytic domain
CNPNMHOP_00901 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CNPNMHOP_00903 4.6e-188 yegU O ADP-ribosylglycohydrolase
CNPNMHOP_00904 4.1e-189 yegV G pfkB family carbohydrate kinase
CNPNMHOP_00905 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
CNPNMHOP_00906 1.5e-103 Q Isochorismatase family
CNPNMHOP_00907 2.3e-214 S Choline/ethanolamine kinase
CNPNMHOP_00908 2.5e-275 eat E Amino acid permease
CNPNMHOP_00909 2e-263 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
CNPNMHOP_00910 3.9e-142 yidP K UTRA
CNPNMHOP_00911 1.6e-120 degU K helix_turn_helix, Lux Regulon
CNPNMHOP_00912 5.1e-282 tcsS3 KT PspC domain
CNPNMHOP_00913 8.3e-146 pspC KT PspC domain
CNPNMHOP_00914 7.1e-93
CNPNMHOP_00915 4.4e-115 S Protein of unknown function (DUF4125)
CNPNMHOP_00916 0.0 S Domain of unknown function (DUF4037)
CNPNMHOP_00917 7e-212 araJ EGP Major facilitator Superfamily
CNPNMHOP_00919 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CNPNMHOP_00920 9.3e-192 K helix_turn _helix lactose operon repressor
CNPNMHOP_00921 8.8e-251 G Psort location CytoplasmicMembrane, score 10.00
CNPNMHOP_00922 4.1e-99 S Serine aminopeptidase, S33
CNPNMHOP_00923 1.1e-206 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CNPNMHOP_00924 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CNPNMHOP_00925 0.0 4.2.1.53 S MCRA family
CNPNMHOP_00926 9e-87 phoU P Plays a role in the regulation of phosphate uptake
CNPNMHOP_00927 4.7e-216 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
CNPNMHOP_00928 6.2e-41
CNPNMHOP_00929 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CNPNMHOP_00930 5.6e-164 usp 3.5.1.28 CBM50 S CHAP domain
CNPNMHOP_00931 1.3e-79 M NlpC/P60 family
CNPNMHOP_00932 2.3e-190 T Universal stress protein family
CNPNMHOP_00933 1e-72 attW O OsmC-like protein
CNPNMHOP_00934 3.8e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CNPNMHOP_00935 2.1e-128 folA 1.5.1.3 H dihydrofolate reductase
CNPNMHOP_00936 3.6e-85 ptpA 3.1.3.48 T low molecular weight
CNPNMHOP_00938 9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CNPNMHOP_00939 5e-170 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CNPNMHOP_00943 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
CNPNMHOP_00944 9.7e-161
CNPNMHOP_00945 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
CNPNMHOP_00946 1.2e-282 pelF GT4 M Domain of unknown function (DUF3492)
CNPNMHOP_00947 1.3e-282 pelG S Putative exopolysaccharide Exporter (EPS-E)
CNPNMHOP_00948 8.6e-310 cotH M CotH kinase protein
CNPNMHOP_00949 2.2e-159 P VTC domain
CNPNMHOP_00950 2.2e-111 S Domain of unknown function (DUF4956)
CNPNMHOP_00951 0.0 yliE T Putative diguanylate phosphodiesterase
CNPNMHOP_00952 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
CNPNMHOP_00953 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
CNPNMHOP_00954 1.1e-236 S AI-2E family transporter
CNPNMHOP_00955 3.1e-231 epsG M Glycosyl transferase family 21
CNPNMHOP_00956 1.1e-232 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
CNPNMHOP_00957 3.3e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CNPNMHOP_00958 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CNPNMHOP_00959 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNPNMHOP_00960 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
CNPNMHOP_00961 1.1e-153 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CNPNMHOP_00962 6.3e-258 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNPNMHOP_00963 3.1e-93 S Protein of unknown function (DUF3180)
CNPNMHOP_00964 5e-165 tesB I Thioesterase-like superfamily
CNPNMHOP_00965 0.0 yjjK S ATP-binding cassette protein, ChvD family
CNPNMHOP_00966 8.5e-181 V Beta-lactamase
CNPNMHOP_00967 9.3e-74 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CNPNMHOP_00968 3.9e-170 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
CNPNMHOP_00970 1.1e-77 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
CNPNMHOP_00971 5.8e-296 S Amidohydrolase family
CNPNMHOP_00972 2.2e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
CNPNMHOP_00973 8.7e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CNPNMHOP_00974 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
CNPNMHOP_00975 2e-183 K Bacterial regulatory proteins, lacI family
CNPNMHOP_00976 9.4e-239 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
CNPNMHOP_00977 1.7e-185 MA20_14025 U Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00978 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_00979 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CNPNMHOP_00980 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
CNPNMHOP_00981 9.7e-09 CE10 I Belongs to the type-B carboxylesterase lipase family
CNPNMHOP_00982 8e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
CNPNMHOP_00983 4.5e-288 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
CNPNMHOP_00984 2e-225 xylR GK ROK family
CNPNMHOP_00986 1.5e-35 rpmE J Binds the 23S rRNA
CNPNMHOP_00987 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CNPNMHOP_00988 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CNPNMHOP_00989 7.8e-219 livK E Receptor family ligand binding region
CNPNMHOP_00990 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
CNPNMHOP_00991 6.7e-196 livM U Belongs to the binding-protein-dependent transport system permease family
CNPNMHOP_00992 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
CNPNMHOP_00993 1.9e-124 livF E ATPases associated with a variety of cellular activities
CNPNMHOP_00994 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
CNPNMHOP_00995 1.7e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
CNPNMHOP_00996 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CNPNMHOP_00997 8.2e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
CNPNMHOP_00998 2.5e-161 supH S Sucrose-6F-phosphate phosphohydrolase
CNPNMHOP_00999 1e-270 recD2 3.6.4.12 L PIF1-like helicase
CNPNMHOP_01000 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CNPNMHOP_01001 5.4e-95 L Single-strand binding protein family
CNPNMHOP_01002 0.0 pepO 3.4.24.71 O Peptidase family M13
CNPNMHOP_01003 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
CNPNMHOP_01004 5.4e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
CNPNMHOP_01005 1.7e-142 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
CNPNMHOP_01006 7.5e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CNPNMHOP_01007 1.1e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNPNMHOP_01008 2.3e-168 ftsE D Cell division ATP-binding protein FtsE
CNPNMHOP_01009 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
CNPNMHOP_01010 8.9e-150 usp 3.5.1.28 CBM50 D CHAP domain protein
CNPNMHOP_01011 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CNPNMHOP_01012 1.1e-156 pknD ET ABC transporter, substrate-binding protein, family 3
CNPNMHOP_01013 1e-35 pknD ET ABC transporter, substrate-binding protein, family 3
CNPNMHOP_01014 6.4e-128 pknD ET ABC transporter, substrate-binding protein, family 3
CNPNMHOP_01015 1.4e-128 yecS E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01016 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
CNPNMHOP_01017 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CNPNMHOP_01018 3e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
CNPNMHOP_01019 3.4e-228 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CNPNMHOP_01020 1.4e-189 K Periplasmic binding protein domain
CNPNMHOP_01021 4.7e-88 L DNA integration
CNPNMHOP_01022 5e-43
CNPNMHOP_01023 5.9e-35 MU outer membrane autotransporter barrel domain protein
CNPNMHOP_01025 2.1e-11
CNPNMHOP_01027 1.8e-88 M Glycosyl hydrolases family 25
CNPNMHOP_01028 2.1e-23 S Putative phage holin Dp-1
CNPNMHOP_01029 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CNPNMHOP_01030 1e-196 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CNPNMHOP_01031 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
CNPNMHOP_01032 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNPNMHOP_01033 2.2e-41 nadR H ATPase kinase involved in NAD metabolism
CNPNMHOP_01034 2.5e-112 pnuC H Nicotinamide mononucleotide transporter
CNPNMHOP_01035 7.1e-09 pnuC H Nicotinamide mononucleotide transporter
CNPNMHOP_01036 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
CNPNMHOP_01037 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
CNPNMHOP_01038 2.4e-32 secG U Preprotein translocase SecG subunit
CNPNMHOP_01039 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CNPNMHOP_01040 4.2e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
CNPNMHOP_01041 1.3e-171 whiA K May be required for sporulation
CNPNMHOP_01042 4e-170 rapZ S Displays ATPase and GTPase activities
CNPNMHOP_01043 7.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
CNPNMHOP_01044 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CNPNMHOP_01045 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CNPNMHOP_01046 2.4e-220 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_01047 0.0 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_01048 1.5e-138 S Domain of unknown function (DUF4194)
CNPNMHOP_01049 2.4e-273 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_01050 2e-13
CNPNMHOP_01052 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CNPNMHOP_01053 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
CNPNMHOP_01054 1.2e-299 ybiT S ABC transporter
CNPNMHOP_01055 5e-176 S IMP dehydrogenase activity
CNPNMHOP_01056 5.7e-277 pepC 3.4.22.40 E Peptidase C1-like family
CNPNMHOP_01057 1.7e-145 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_01058 2.8e-144
CNPNMHOP_01059 9e-98
CNPNMHOP_01062 1.5e-181 cat P Cation efflux family
CNPNMHOP_01063 3.6e-76 S Psort location CytoplasmicMembrane, score
CNPNMHOP_01064 2.7e-221 yxjG_1 E Psort location Cytoplasmic, score 8.87
CNPNMHOP_01065 1.5e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
CNPNMHOP_01066 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
CNPNMHOP_01067 6.7e-72 K MerR family regulatory protein
CNPNMHOP_01068 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
CNPNMHOP_01069 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
CNPNMHOP_01070 2.1e-119 yoaP E YoaP-like
CNPNMHOP_01072 3.1e-195 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CNPNMHOP_01073 2.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
CNPNMHOP_01074 1.3e-148 yeaZ 2.3.1.234 O Glycoprotease family
CNPNMHOP_01075 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
CNPNMHOP_01076 5.5e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
CNPNMHOP_01077 0.0 comE S Competence protein
CNPNMHOP_01078 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
CNPNMHOP_01079 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CNPNMHOP_01080 7.9e-139 ET Bacterial periplasmic substrate-binding proteins
CNPNMHOP_01081 5.7e-172 corA P CorA-like Mg2+ transporter protein
CNPNMHOP_01082 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CNPNMHOP_01083 5.2e-65 3.4.22.70 M Sortase family
CNPNMHOP_01084 5.6e-83 3.4.22.70 M Sortase family
CNPNMHOP_01085 2.7e-302 M domain protein
CNPNMHOP_01086 9.2e-71 pdxH S Pfam:Pyridox_oxidase
CNPNMHOP_01087 4.5e-233 XK27_00240 K Fic/DOC family
CNPNMHOP_01089 1.6e-117
CNPNMHOP_01090 5.6e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
CNPNMHOP_01091 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CNPNMHOP_01092 2.9e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CNPNMHOP_01093 7.6e-71 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CNPNMHOP_01094 3e-107 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
CNPNMHOP_01095 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
CNPNMHOP_01096 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
CNPNMHOP_01097 1.7e-266 G ABC transporter substrate-binding protein
CNPNMHOP_01098 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
CNPNMHOP_01099 3.3e-96 M Peptidase family M23
CNPNMHOP_01100 1.6e-61
CNPNMHOP_01103 5e-125 XK27_06785 V ABC transporter
CNPNMHOP_01104 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CNPNMHOP_01105 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CNPNMHOP_01106 5.1e-139 S SdpI/YhfL protein family
CNPNMHOP_01107 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
CNPNMHOP_01108 8.8e-121 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
CNPNMHOP_01109 3.4e-216 yxjG_1 E Psort location Cytoplasmic, score 8.87
CNPNMHOP_01110 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNPNMHOP_01111 2e-108 J Acetyltransferase (GNAT) domain
CNPNMHOP_01112 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CNPNMHOP_01113 9.2e-161 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
CNPNMHOP_01114 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNPNMHOP_01115 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CNPNMHOP_01116 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
CNPNMHOP_01117 7e-178 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
CNPNMHOP_01118 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CNPNMHOP_01119 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
CNPNMHOP_01120 5.1e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CNPNMHOP_01121 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
CNPNMHOP_01122 1.6e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
CNPNMHOP_01123 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CNPNMHOP_01124 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
CNPNMHOP_01125 1.1e-197 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
CNPNMHOP_01126 1.9e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
CNPNMHOP_01127 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
CNPNMHOP_01128 2e-74
CNPNMHOP_01129 1.9e-305 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
CNPNMHOP_01130 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
CNPNMHOP_01131 1.3e-235 F Psort location CytoplasmicMembrane, score 10.00
CNPNMHOP_01132 2.1e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
CNPNMHOP_01133 1.2e-288 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
CNPNMHOP_01134 2.5e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
CNPNMHOP_01135 4.3e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
CNPNMHOP_01136 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CNPNMHOP_01137 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
CNPNMHOP_01138 2.4e-133 S UPF0126 domain
CNPNMHOP_01139 2.5e-227 ilvE 2.6.1.42 E Amino-transferase class IV
CNPNMHOP_01141 6.6e-50 K Acetyltransferase (GNAT) domain
CNPNMHOP_01142 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNPNMHOP_01143 7.2e-77 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CNPNMHOP_01144 6.5e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CNPNMHOP_01145 1.9e-194 S alpha beta
CNPNMHOP_01146 6.5e-25 yhjX EGP Major facilitator Superfamily
CNPNMHOP_01147 2.2e-29 EGP Major facilitator Superfamily
CNPNMHOP_01148 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNPNMHOP_01149 3.1e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNPNMHOP_01151 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNPNMHOP_01152 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
CNPNMHOP_01153 1.1e-39 nrdH O Glutaredoxin
CNPNMHOP_01154 5.4e-121 K Bacterial regulatory proteins, tetR family
CNPNMHOP_01155 5.1e-224 G Transmembrane secretion effector
CNPNMHOP_01157 4.2e-269 S Psort location Cytoplasmic, score 8.87
CNPNMHOP_01158 4.6e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
CNPNMHOP_01159 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
CNPNMHOP_01160 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
CNPNMHOP_01161 0.0 fadD 6.2.1.3 I AMP-binding enzyme
CNPNMHOP_01162 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CNPNMHOP_01163 3.8e-249 corC S CBS domain
CNPNMHOP_01164 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CNPNMHOP_01165 1.3e-207 phoH T PhoH-like protein
CNPNMHOP_01166 5.3e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
CNPNMHOP_01167 6.5e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CNPNMHOP_01169 2.6e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
CNPNMHOP_01170 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CNPNMHOP_01171 1e-107 yitW S Iron-sulfur cluster assembly protein
CNPNMHOP_01172 3.4e-100 iscU C SUF system FeS assembly protein, NifU family
CNPNMHOP_01173 2.5e-239 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNPNMHOP_01174 1e-142 sufC O FeS assembly ATPase SufC
CNPNMHOP_01175 6.1e-235 sufD O FeS assembly protein SufD
CNPNMHOP_01176 1.6e-290 sufB O FeS assembly protein SufB
CNPNMHOP_01177 0.0 S L,D-transpeptidase catalytic domain
CNPNMHOP_01178 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CNPNMHOP_01179 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
CNPNMHOP_01180 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
CNPNMHOP_01181 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CNPNMHOP_01182 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CNPNMHOP_01183 9.3e-57 3.4.23.43 S Type IV leader peptidase family
CNPNMHOP_01184 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CNPNMHOP_01185 1e-81 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CNPNMHOP_01186 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CNPNMHOP_01187 2.5e-36
CNPNMHOP_01188 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
CNPNMHOP_01189 5.6e-129 pgm3 G Phosphoglycerate mutase family
CNPNMHOP_01190 9.4e-39 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
CNPNMHOP_01191 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CNPNMHOP_01192 9.2e-150 lolD V ABC transporter
CNPNMHOP_01193 1.8e-215 V FtsX-like permease family
CNPNMHOP_01194 1.7e-61 S Domain of unknown function (DUF4418)
CNPNMHOP_01195 0.0 pcrA 3.6.4.12 L DNA helicase
CNPNMHOP_01196 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CNPNMHOP_01197 2.8e-244 pbuX F Permease family
CNPNMHOP_01198 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01199 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNPNMHOP_01200 3e-301 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CNPNMHOP_01201 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
CNPNMHOP_01202 4.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CNPNMHOP_01203 5.8e-76 yiaC K Acetyltransferase (GNAT) domain
CNPNMHOP_01204 5.9e-71 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
CNPNMHOP_01205 6.4e-254 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CNPNMHOP_01207 1.4e-212 ykiI
CNPNMHOP_01208 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CNPNMHOP_01209 3.4e-123 3.6.1.13 L NUDIX domain
CNPNMHOP_01210 7.6e-174 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
CNPNMHOP_01211 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CNPNMHOP_01212 9.4e-101 pdtaR T Response regulator receiver domain protein
CNPNMHOP_01213 3e-164 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
CNPNMHOP_01214 1.3e-187 hbd2 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain
CNPNMHOP_01215 2.9e-77 L Phage integrase family
CNPNMHOP_01216 1.2e-59 L Phage integrase family
CNPNMHOP_01217 3e-145 K Transcriptional regulator
CNPNMHOP_01218 1.5e-130
CNPNMHOP_01220 4.6e-12 IQ Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)
CNPNMHOP_01221 8.3e-18
CNPNMHOP_01222 2e-171 L Transposase, Mutator family
CNPNMHOP_01223 9.3e-60 GT2,GT4 S Transposase
CNPNMHOP_01224 0.0 S Protein of unknown function (DUF499)
CNPNMHOP_01225 2.9e-301 L Protein of unknown function (DUF1156)
CNPNMHOP_01226 0.0 L DEAD-like helicases superfamily
CNPNMHOP_01227 1.2e-13
CNPNMHOP_01228 3.8e-18
CNPNMHOP_01229 2.5e-09 insK L Integrase core domain
CNPNMHOP_01231 1.8e-15
CNPNMHOP_01232 6.6e-70 topB 5.99.1.2 L DNA topoisomerase
CNPNMHOP_01234 2.3e-273 pyk 2.7.1.40 G Pyruvate kinase
CNPNMHOP_01235 8.8e-176 terC P Integral membrane protein, TerC family
CNPNMHOP_01236 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CNPNMHOP_01237 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CNPNMHOP_01238 8.3e-255 rpsA J Ribosomal protein S1
CNPNMHOP_01239 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CNPNMHOP_01240 1.5e-171 P Zinc-uptake complex component A periplasmic
CNPNMHOP_01241 2e-160 znuC P ATPases associated with a variety of cellular activities
CNPNMHOP_01242 1.7e-140 znuB U ABC 3 transport family
CNPNMHOP_01243 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CNPNMHOP_01244 3e-102 carD K CarD-like/TRCF domain
CNPNMHOP_01245 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CNPNMHOP_01246 2e-129 T Response regulator receiver domain protein
CNPNMHOP_01247 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
CNPNMHOP_01248 2.5e-138 ctsW S Phosphoribosyl transferase domain
CNPNMHOP_01249 1.1e-152 cof 5.2.1.8 T Eukaryotic phosphomannomutase
CNPNMHOP_01250 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
CNPNMHOP_01251 8.7e-223
CNPNMHOP_01252 0.0 S Glycosyl transferase, family 2
CNPNMHOP_01253 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CNPNMHOP_01254 5.7e-208 K Cell envelope-related transcriptional attenuator domain
CNPNMHOP_01256 1.8e-170 K Cell envelope-related transcriptional attenuator domain
CNPNMHOP_01257 0.0 D FtsK/SpoIIIE family
CNPNMHOP_01258 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
CNPNMHOP_01259 6e-277 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
CNPNMHOP_01260 1.8e-143 yplQ S Haemolysin-III related
CNPNMHOP_01261 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CNPNMHOP_01262 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
CNPNMHOP_01263 6.1e-282 sdaA 4.3.1.17 E Serine dehydratase alpha chain
CNPNMHOP_01264 6.7e-91
CNPNMHOP_01266 1.9e-71 P Major Facilitator Superfamily
CNPNMHOP_01268 1.7e-182 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
CNPNMHOP_01269 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
CNPNMHOP_01270 2e-71 divIC D Septum formation initiator
CNPNMHOP_01271 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CNPNMHOP_01272 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CNPNMHOP_01273 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CNPNMHOP_01274 1.1e-92 2.3.1.183 M Acetyltransferase (GNAT) domain
CNPNMHOP_01275 0.0 S Uncharacterised protein family (UPF0182)
CNPNMHOP_01276 9.6e-180 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
CNPNMHOP_01277 4e-39 ybdD S Selenoprotein, putative
CNPNMHOP_01278 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
CNPNMHOP_01279 3.2e-53 azlD E Branched-chain amino acid transport protein (AzlD)
CNPNMHOP_01280 1.1e-141 azlC E AzlC protein
CNPNMHOP_01281 1.1e-86 M Protein of unknown function (DUF3737)
CNPNMHOP_01282 1.8e-81 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CNPNMHOP_01283 4.9e-145 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
CNPNMHOP_01284 5e-176 opcA G Glucose-6-phosphate dehydrogenase subunit
CNPNMHOP_01285 1.8e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CNPNMHOP_01286 9.4e-219 patB 4.4.1.8 E Aminotransferase, class I II
CNPNMHOP_01287 3.4e-146 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CNPNMHOP_01288 9.9e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CNPNMHOP_01289 0.0 lysX S Uncharacterised conserved protein (DUF2156)
CNPNMHOP_01290 2.9e-241 S Putative esterase
CNPNMHOP_01291 1e-140 ybbL V ATPases associated with a variety of cellular activities
CNPNMHOP_01292 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
CNPNMHOP_01293 4.3e-273 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
CNPNMHOP_01294 4.2e-127 S Enoyl-(Acyl carrier protein) reductase
CNPNMHOP_01295 2.4e-234 rutG F Permease family
CNPNMHOP_01296 5.4e-155 3.1.3.73 G Phosphoglycerate mutase family
CNPNMHOP_01297 7e-141 K helix_turn_helix, arabinose operon control protein
CNPNMHOP_01298 4e-137 S Sulfite exporter TauE/SafE
CNPNMHOP_01299 8.5e-70 S ECF transporter, substrate-specific component
CNPNMHOP_01300 3.2e-78 2.7.1.48 F uridine kinase
CNPNMHOP_01301 3.1e-167 korD 1.2.7.3 C Domain of unknown function (DUF362)
CNPNMHOP_01302 3e-224 C Na H antiporter family protein
CNPNMHOP_01303 1.8e-176 MA20_14895 S Conserved hypothetical protein 698
CNPNMHOP_01304 7e-118
CNPNMHOP_01305 3.7e-16 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CNPNMHOP_01306 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_01307 0.0 abfA1 3.2.1.55 GH51 G arabinose metabolic process
CNPNMHOP_01308 2.2e-246 G Bacterial extracellular solute-binding protein
CNPNMHOP_01309 5.3e-275 G Bacterial extracellular solute-binding protein
CNPNMHOP_01310 1.3e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CNPNMHOP_01311 7e-242 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CNPNMHOP_01312 5.6e-292 E ABC transporter, substrate-binding protein, family 5
CNPNMHOP_01313 3.7e-166 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01314 1.2e-139 EP Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01315 7.1e-136 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
CNPNMHOP_01316 1.2e-138 sapF E ATPases associated with a variety of cellular activities
CNPNMHOP_01317 8.4e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
CNPNMHOP_01318 1e-218 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
CNPNMHOP_01319 0.0 macB_2 V ATPases associated with a variety of cellular activities
CNPNMHOP_01320 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
CNPNMHOP_01321 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CNPNMHOP_01322 2.7e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNPNMHOP_01323 3.1e-270 yhdG E aromatic amino acid transport protein AroP K03293
CNPNMHOP_01324 5.9e-307 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNPNMHOP_01325 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CNPNMHOP_01326 1.5e-214 ybiR P Citrate transporter
CNPNMHOP_01327 8.8e-176 ydcZ S Putative inner membrane exporter, YdcZ
CNPNMHOP_01329 0.0 tetP J Elongation factor G, domain IV
CNPNMHOP_01333 2.9e-100 K acetyltransferase
CNPNMHOP_01334 1.1e-108 papP E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01335 3.6e-120 E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01336 2.4e-150 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
CNPNMHOP_01337 6.9e-143 cjaA ET Bacterial periplasmic substrate-binding proteins
CNPNMHOP_01338 1.4e-200 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CNPNMHOP_01339 9e-156 metQ M NLPA lipoprotein
CNPNMHOP_01340 1e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNPNMHOP_01341 4.9e-98 metI P Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01342 5.7e-222 mtnE 2.6.1.83 E Aminotransferase class I and II
CNPNMHOP_01343 9.4e-75 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
CNPNMHOP_01344 2.8e-15 P Belongs to the ABC transporter superfamily
CNPNMHOP_01345 3e-43 XAC3035 O Glutaredoxin
CNPNMHOP_01346 3.1e-127 XK27_08050 O prohibitin homologues
CNPNMHOP_01347 6.9e-15 S Domain of unknown function (DUF4143)
CNPNMHOP_01348 3.7e-74
CNPNMHOP_01349 4.8e-134 V ATPases associated with a variety of cellular activities
CNPNMHOP_01350 2.8e-146 M Conserved repeat domain
CNPNMHOP_01351 6.4e-255 macB_8 V MacB-like periplasmic core domain
CNPNMHOP_01352 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNPNMHOP_01353 1.2e-183 adh3 C Zinc-binding dehydrogenase
CNPNMHOP_01354 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CNPNMHOP_01355 1.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CNPNMHOP_01356 2.3e-89 zur P Belongs to the Fur family
CNPNMHOP_01357 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
CNPNMHOP_01358 3.6e-202 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
CNPNMHOP_01359 2.7e-188 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
CNPNMHOP_01360 7.4e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
CNPNMHOP_01361 2.5e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
CNPNMHOP_01362 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
CNPNMHOP_01363 2.1e-247 EGP Major facilitator Superfamily
CNPNMHOP_01364 9.7e-236 purD 6.3.4.13 F Belongs to the GARS family
CNPNMHOP_01365 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CNPNMHOP_01366 1.4e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CNPNMHOP_01367 2.5e-308 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
CNPNMHOP_01368 1.9e-36
CNPNMHOP_01369 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
CNPNMHOP_01370 9.5e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CNPNMHOP_01371 8.2e-227 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CNPNMHOP_01372 6.5e-226 M Glycosyl transferase 4-like domain
CNPNMHOP_01373 2.5e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
CNPNMHOP_01375 1.8e-187 yocS S SBF-like CPA transporter family (DUF4137)
CNPNMHOP_01377 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CNPNMHOP_01378 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CNPNMHOP_01379 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CNPNMHOP_01380 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CNPNMHOP_01381 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CNPNMHOP_01382 1.8e-75 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CNPNMHOP_01383 1.1e-239 carA 6.3.5.5 F Belongs to the CarA family
CNPNMHOP_01384 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
CNPNMHOP_01385 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
CNPNMHOP_01386 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
CNPNMHOP_01388 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
CNPNMHOP_01389 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CNPNMHOP_01390 7.9e-227 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CNPNMHOP_01391 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNPNMHOP_01392 7.1e-135 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CNPNMHOP_01393 1.1e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CNPNMHOP_01394 3.5e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
CNPNMHOP_01395 3.8e-282 arc O AAA ATPase forming ring-shaped complexes
CNPNMHOP_01396 2.3e-301 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
CNPNMHOP_01397 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
CNPNMHOP_01398 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
CNPNMHOP_01399 2.2e-279 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
CNPNMHOP_01400 9.7e-141 C FMN binding
CNPNMHOP_01401 8.7e-57
CNPNMHOP_01402 1.4e-41 hup L Belongs to the bacterial histone-like protein family
CNPNMHOP_01403 0.0 S Lysylphosphatidylglycerol synthase TM region
CNPNMHOP_01404 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
CNPNMHOP_01405 1e-276 S PGAP1-like protein
CNPNMHOP_01406 1.3e-62
CNPNMHOP_01407 1.9e-181 S von Willebrand factor (vWF) type A domain
CNPNMHOP_01408 1.6e-191 S von Willebrand factor (vWF) type A domain
CNPNMHOP_01409 3.6e-91
CNPNMHOP_01410 4.2e-175 S Protein of unknown function DUF58
CNPNMHOP_01411 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
CNPNMHOP_01412 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CNPNMHOP_01413 8.5e-77 S LytR cell envelope-related transcriptional attenuator
CNPNMHOP_01414 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CNPNMHOP_01416 1.3e-124
CNPNMHOP_01417 6.8e-133 KT Response regulator receiver domain protein
CNPNMHOP_01418 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
CNPNMHOP_01419 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
CNPNMHOP_01420 1.2e-182 S Protein of unknown function (DUF3027)
CNPNMHOP_01421 4.6e-188 uspA T Belongs to the universal stress protein A family
CNPNMHOP_01422 0.0 clpC O ATPase family associated with various cellular activities (AAA)
CNPNMHOP_01423 1.5e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
CNPNMHOP_01424 2.3e-284 purR QT Purine catabolism regulatory protein-like family
CNPNMHOP_01425 5e-246 proP EGP Sugar (and other) transporter
CNPNMHOP_01426 4.6e-140 3.5.2.10 S Creatinine amidohydrolase
CNPNMHOP_01427 2.6e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
CNPNMHOP_01428 5.8e-250 hisS 6.1.1.21 J Histidyl-tRNA synthetase
CNPNMHOP_01429 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CNPNMHOP_01431 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01432 3.3e-138 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
CNPNMHOP_01433 1.4e-136 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
CNPNMHOP_01434 6.8e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
CNPNMHOP_01435 3.1e-111 gluC E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01436 1e-199 gluD E Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01437 1.3e-190 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
CNPNMHOP_01438 0.0 L DEAD DEAH box helicase
CNPNMHOP_01439 3.1e-251 rarA L Recombination factor protein RarA
CNPNMHOP_01440 2.9e-258 EGP Major facilitator Superfamily
CNPNMHOP_01441 9.2e-311 E ABC transporter, substrate-binding protein, family 5
CNPNMHOP_01442 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CNPNMHOP_01443 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CNPNMHOP_01444 8.8e-240 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CNPNMHOP_01446 3.3e-245 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNPNMHOP_01447 4.8e-117 safC S O-methyltransferase
CNPNMHOP_01448 5.2e-178 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
CNPNMHOP_01449 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
CNPNMHOP_01450 2.7e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
CNPNMHOP_01451 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
CNPNMHOP_01452 3.1e-83 yraN L Belongs to the UPF0102 family
CNPNMHOP_01453 2.2e-162 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
CNPNMHOP_01454 1.7e-251 metY 2.5.1.49 E Aminotransferase class-V
CNPNMHOP_01455 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
CNPNMHOP_01456 5.1e-306 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
CNPNMHOP_01457 6.9e-150 P Cobalt transport protein
CNPNMHOP_01458 8.2e-193 K helix_turn_helix ASNC type
CNPNMHOP_01459 2.8e-140 V ABC transporter, ATP-binding protein
CNPNMHOP_01460 0.0 MV MacB-like periplasmic core domain
CNPNMHOP_01461 1.1e-125 K helix_turn_helix, Lux Regulon
CNPNMHOP_01462 0.0 tcsS2 T Histidine kinase
CNPNMHOP_01463 1.5e-266 pip 3.4.11.5 S alpha/beta hydrolase fold
CNPNMHOP_01464 7.7e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CNPNMHOP_01465 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CNPNMHOP_01466 2.6e-241 S HipA-like C-terminal domain
CNPNMHOP_01467 5.5e-11 K addiction module antidote protein HigA
CNPNMHOP_01468 3e-213 G Transmembrane secretion effector
CNPNMHOP_01469 6.6e-119 K Bacterial regulatory proteins, tetR family
CNPNMHOP_01470 8e-58 yccF S Inner membrane component domain
CNPNMHOP_01471 1e-11
CNPNMHOP_01472 4.1e-54 cysB 4.2.1.22 EGP Major facilitator Superfamily
CNPNMHOP_01473 1.3e-25 cysB 4.2.1.22 EGP Major facilitator Superfamily
CNPNMHOP_01474 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_01475 8.9e-198 K helix_turn _helix lactose operon repressor
CNPNMHOP_01476 3.6e-241 mntH P H( )-stimulated, divalent metal cation uptake system
CNPNMHOP_01477 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
CNPNMHOP_01478 6.8e-126 L Protein of unknown function (DUF1524)
CNPNMHOP_01479 1.2e-244 T Diguanylate cyclase (GGDEF) domain protein
CNPNMHOP_01480 1.4e-284 EGP Major facilitator Superfamily
CNPNMHOP_01481 9.6e-47
CNPNMHOP_01482 9.3e-189 S Endonuclease/Exonuclease/phosphatase family
CNPNMHOP_01483 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
CNPNMHOP_01484 0.0 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CNPNMHOP_01485 8.6e-187
CNPNMHOP_01486 3.2e-13 S enterobacterial common antigen metabolic process
CNPNMHOP_01487 8.5e-08 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
CNPNMHOP_01489 2.2e-36 S enterobacterial common antigen metabolic process
CNPNMHOP_01490 3.7e-89 S enterobacterial common antigen metabolic process
CNPNMHOP_01491 2.7e-20 pslL G Acyltransferase family
CNPNMHOP_01492 7.2e-176 wzy S EpsG family
CNPNMHOP_01494 5.7e-194 1.13.11.79 C Psort location Cytoplasmic, score 8.87
CNPNMHOP_01495 2.1e-210 S Polysaccharide pyruvyl transferase
CNPNMHOP_01496 2.7e-110 H Hexapeptide repeat of succinyl-transferase
CNPNMHOP_01497 9.5e-197 S Glycosyltransferase like family 2
CNPNMHOP_01498 2.3e-249 cps2J S Polysaccharide biosynthesis protein
CNPNMHOP_01499 8.5e-240 MA20_17390 GT4 M Glycosyl transferases group 1
CNPNMHOP_01500 5.6e-203 GT4 M Psort location Cytoplasmic, score 8.87
CNPNMHOP_01501 4.8e-218 M Domain of unknown function (DUF1972)
CNPNMHOP_01502 1e-211 M Glycosyl transferase 4-like domain
CNPNMHOP_01503 2.6e-83 GT2 S Glycosyltransferase like family 2
CNPNMHOP_01504 9.5e-40 M Glycosyl transferase, family 2
CNPNMHOP_01506 5.2e-74 H Core-2/I-Branching enzyme
CNPNMHOP_01507 3e-32 2.3.1.30 E serine acetyltransferase
CNPNMHOP_01508 5.4e-153 S Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01509 1.8e-12 L PFAM Integrase catalytic
CNPNMHOP_01510 2.9e-13 L Transposase, Mutator family
CNPNMHOP_01511 1.7e-153
CNPNMHOP_01512 4e-18
CNPNMHOP_01514 5.5e-30 S enterobacterial common antigen metabolic process
CNPNMHOP_01516 2.1e-25 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CNPNMHOP_01518 2.3e-79 S RloB-like protein
CNPNMHOP_01519 1.6e-185 S AAA domain, putative AbiEii toxin, Type IV TA system
CNPNMHOP_01520 2.2e-95 S enterobacterial common antigen metabolic process
CNPNMHOP_01521 5.2e-48 S enterobacterial common antigen metabolic process
CNPNMHOP_01522 2e-103
CNPNMHOP_01523 2.1e-135 S Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01524 3.4e-56 yccF S Inner membrane component domain
CNPNMHOP_01525 0.0 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
CNPNMHOP_01526 4.3e-144 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01527 1.4e-162 G PFAM binding-protein-dependent transport systems inner membrane component
CNPNMHOP_01528 2.3e-223 G Bacterial extracellular solute-binding protein
CNPNMHOP_01529 2.4e-181 K helix_turn _helix lactose operon repressor
CNPNMHOP_01530 1.8e-184 K Psort location Cytoplasmic, score
CNPNMHOP_01531 3e-270 G Bacterial extracellular solute-binding protein
CNPNMHOP_01532 1.7e-162 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01533 6.5e-148 P Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01534 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
CNPNMHOP_01535 5.5e-246 wcoI DM Psort location CytoplasmicMembrane, score
CNPNMHOP_01536 1.3e-96 3.1.3.48 T Low molecular weight phosphatase family
CNPNMHOP_01537 1.9e-44
CNPNMHOP_01538 1.6e-28 K Cro/C1-type HTH DNA-binding domain
CNPNMHOP_01539 3.6e-70
CNPNMHOP_01540 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CNPNMHOP_01541 4.4e-157 cps1D M Domain of unknown function (DUF4422)
CNPNMHOP_01542 1.1e-189 2.4.1.166 GT2 M Glycosyltransferase like family 2
CNPNMHOP_01543 5.6e-253 S Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01544 2.2e-285 S Psort location CytoplasmicMembrane, score 9.99
CNPNMHOP_01545 1e-206 wbbI M transferase activity, transferring glycosyl groups
CNPNMHOP_01546 1.8e-190 1.13.11.79 C Psort location Cytoplasmic, score 8.87
CNPNMHOP_01547 1.4e-209 GT2 M Glycosyltransferase like family 2
CNPNMHOP_01548 5.1e-223 C Polysaccharide pyruvyl transferase
CNPNMHOP_01549 0.0 amyE 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CNPNMHOP_01550 2.1e-88
CNPNMHOP_01551 5.6e-170 S G5
CNPNMHOP_01552 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
CNPNMHOP_01553 1.7e-113 F Domain of unknown function (DUF4916)
CNPNMHOP_01554 7.4e-155 mhpC I Alpha/beta hydrolase family
CNPNMHOP_01555 3e-209 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
CNPNMHOP_01556 2.7e-70 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
CNPNMHOP_01557 3.3e-236 S Uncharacterized conserved protein (DUF2183)
CNPNMHOP_01558 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
CNPNMHOP_01559 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CNPNMHOP_01560 1.5e-87 J TM2 domain
CNPNMHOP_01561 9.1e-217 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
CNPNMHOP_01562 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
CNPNMHOP_01563 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
CNPNMHOP_01564 6.7e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
CNPNMHOP_01565 3.8e-223 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
CNPNMHOP_01566 3.4e-141 glpR K DeoR C terminal sensor domain
CNPNMHOP_01567 4e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
CNPNMHOP_01568 9e-234 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
CNPNMHOP_01569 4e-23 lmrB EGP Major facilitator Superfamily
CNPNMHOP_01570 7.1e-43 gcvR T Belongs to the UPF0237 family
CNPNMHOP_01571 7.2e-253 S UPF0210 protein
CNPNMHOP_01572 3.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CNPNMHOP_01573 3.5e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
CNPNMHOP_01574 6.8e-100
CNPNMHOP_01575 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNPNMHOP_01576 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CNPNMHOP_01577 1.8e-101 T Forkhead associated domain
CNPNMHOP_01578 4.8e-104 B Belongs to the OprB family
CNPNMHOP_01579 9.9e-163 3.1.3.16 T Sigma factor PP2C-like phosphatases
CNPNMHOP_01580 0.0 E Transglutaminase-like superfamily
CNPNMHOP_01581 8.3e-221 S Protein of unknown function DUF58
CNPNMHOP_01582 3.1e-227 S ATPase family associated with various cellular activities (AAA)
CNPNMHOP_01583 0.0 S Fibronectin type 3 domain
CNPNMHOP_01584 1e-266 KLT Protein tyrosine kinase
CNPNMHOP_01585 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
CNPNMHOP_01586 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
CNPNMHOP_01587 1.4e-216 G Major Facilitator Superfamily
CNPNMHOP_01588 1.4e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CNPNMHOP_01589 2.8e-37 csoR S Metal-sensitive transcriptional repressor
CNPNMHOP_01590 0.0 pacS 3.6.3.54 P E1-E2 ATPase
CNPNMHOP_01591 9.5e-175 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNPNMHOP_01592 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CNPNMHOP_01593 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
CNPNMHOP_01594 1.5e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CNPNMHOP_01595 5.2e-116 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CNPNMHOP_01596 5.7e-286 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
CNPNMHOP_01597 9.1e-240 G Bacterial extracellular solute-binding protein
CNPNMHOP_01598 3.3e-127 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CNPNMHOP_01599 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CNPNMHOP_01600 0.0 cydD V ABC transporter transmembrane region
CNPNMHOP_01601 0.0 fadD 6.2.1.3 I AMP-binding enzyme
CNPNMHOP_01602 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CNPNMHOP_01603 1.5e-129 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
CNPNMHOP_01604 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
CNPNMHOP_01605 3.1e-209 K helix_turn _helix lactose operon repressor
CNPNMHOP_01606 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
CNPNMHOP_01607 1.2e-188 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CNPNMHOP_01608 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
CNPNMHOP_01609 2.4e-292 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CNPNMHOP_01610 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CNPNMHOP_01611 2.2e-271 mmuP E amino acid
CNPNMHOP_01612 2.7e-59 psp1 3.5.99.10 J Endoribonuclease L-PSP
CNPNMHOP_01614 4.7e-122 cyaA 4.6.1.1 S CYTH
CNPNMHOP_01615 1.2e-169 trxA2 O Tetratricopeptide repeat
CNPNMHOP_01616 1.7e-179
CNPNMHOP_01617 4.8e-195
CNPNMHOP_01618 1.1e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
CNPNMHOP_01619 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
CNPNMHOP_01620 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CNPNMHOP_01621 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CNPNMHOP_01622 3.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CNPNMHOP_01623 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CNPNMHOP_01624 4.5e-149 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNPNMHOP_01625 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CNPNMHOP_01626 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CNPNMHOP_01627 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
CNPNMHOP_01628 4.5e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CNPNMHOP_01630 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
CNPNMHOP_01631 3.3e-192 yfdV S Membrane transport protein
CNPNMHOP_01632 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
CNPNMHOP_01633 3.5e-174 M LPXTG-motif cell wall anchor domain protein
CNPNMHOP_01634 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
CNPNMHOP_01635 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNPNMHOP_01636 9.4e-98 mntP P Probably functions as a manganese efflux pump
CNPNMHOP_01637 4.9e-134
CNPNMHOP_01638 8.4e-134 KT Transcriptional regulatory protein, C terminal
CNPNMHOP_01639 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CNPNMHOP_01640 7.8e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
CNPNMHOP_01641 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CNPNMHOP_01642 0.0 S domain protein
CNPNMHOP_01643 1.8e-69 tyrA 5.4.99.5 E Chorismate mutase type II
CNPNMHOP_01644 1.3e-79 K helix_turn_helix ASNC type
CNPNMHOP_01645 5.1e-245 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CNPNMHOP_01646 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
CNPNMHOP_01647 2.1e-51 S Protein of unknown function (DUF2469)
CNPNMHOP_01648 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
CNPNMHOP_01649 8.7e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CNPNMHOP_01650 8.6e-287 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CNPNMHOP_01651 5e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CNPNMHOP_01652 6.2e-134 K Psort location Cytoplasmic, score
CNPNMHOP_01653 3.1e-133 spoU 2.1.1.185 J RNA methyltransferase TrmH family
CNPNMHOP_01654 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CNPNMHOP_01655 3.4e-170 rmuC S RmuC family
CNPNMHOP_01656 6.8e-135 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
CNPNMHOP_01657 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
CNPNMHOP_01658 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
CNPNMHOP_01659 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CNPNMHOP_01660 2.5e-80
CNPNMHOP_01661 6.3e-210 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
CNPNMHOP_01662 4.8e-39 M Protein of unknown function (DUF3152)
CNPNMHOP_01663 1.4e-125 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CNPNMHOP_01664 3.4e-19 S zinc-ribbon domain
CNPNMHOP_01666 1.5e-167 T Pfam Adenylate and Guanylate cyclase catalytic domain
CNPNMHOP_01667 2.9e-292 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CNPNMHOP_01668 1.7e-70 rplI J Binds to the 23S rRNA
CNPNMHOP_01669 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CNPNMHOP_01670 9.7e-70 ssb1 L Single-stranded DNA-binding protein
CNPNMHOP_01671 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CNPNMHOP_01672 3.3e-186 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CNPNMHOP_01673 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNPNMHOP_01674 1.1e-259 EGP Major Facilitator Superfamily
CNPNMHOP_01675 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
CNPNMHOP_01676 2e-197 K helix_turn _helix lactose operon repressor
CNPNMHOP_01677 2.6e-61
CNPNMHOP_01678 1.1e-17 relB L RelB antitoxin
CNPNMHOP_01679 6.4e-24 S Addiction module toxin, RelE StbE family
CNPNMHOP_01680 1.1e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CNPNMHOP_01681 5.9e-255 S Domain of unknown function (DUF4143)
CNPNMHOP_01682 4.5e-288 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
CNPNMHOP_01683 2.7e-224 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
CNPNMHOP_01684 2.9e-136 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
CNPNMHOP_01685 1.4e-181 M Glycosyl transferases group 1
CNPNMHOP_01686 3.6e-174 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
CNPNMHOP_01687 7.1e-109 rgpC U Transport permease protein
CNPNMHOP_01688 6.4e-71 S Acyltransferase family
CNPNMHOP_01689 4.7e-78 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CNPNMHOP_01690 2.8e-155 rfbJ M Glycosyl transferase family 2
CNPNMHOP_01691 2e-291 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
CNPNMHOP_01692 8.9e-259 S AAA domain
CNPNMHOP_01693 3.1e-69
CNPNMHOP_01694 1e-10
CNPNMHOP_01695 1.3e-296 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
CNPNMHOP_01696 2.8e-58
CNPNMHOP_01698 5.7e-25 S Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
CNPNMHOP_01699 6.1e-16 S BrnA antitoxin of type II toxin-antitoxin system
CNPNMHOP_01700 5.2e-43 K Cro/C1-type HTH DNA-binding domain
CNPNMHOP_01701 7.1e-16
CNPNMHOP_01702 1.1e-150 ltrBE1 U Relaxase/Mobilisation nuclease domain
CNPNMHOP_01703 3.3e-28 S Bacterial mobilisation protein (MobC)
CNPNMHOP_01705 0.0 V Type II restriction enzyme, methylase subunits
CNPNMHOP_01710 2.2e-98
CNPNMHOP_01711 1.9e-10
CNPNMHOP_01712 5.9e-120 L Phage integrase, N-terminal SAM-like domain
CNPNMHOP_01714 1.2e-92 EGP Major facilitator Superfamily
CNPNMHOP_01715 2.2e-58 EGP Major facilitator Superfamily
CNPNMHOP_01716 9.8e-155 clcA P Voltage gated chloride channel
CNPNMHOP_01717 3.5e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CNPNMHOP_01718 3.2e-217 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
CNPNMHOP_01719 0.0 pip S YhgE Pip domain protein
CNPNMHOP_01720 0.0 pip S YhgE Pip domain protein
CNPNMHOP_01721 1.3e-169 yddG EG EamA-like transporter family
CNPNMHOP_01722 3.2e-65 K Helix-turn-helix XRE-family like proteins
CNPNMHOP_01724 1.2e-186 htpX O Belongs to the peptidase M48B family
CNPNMHOP_01725 3.1e-270 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
CNPNMHOP_01726 1.9e-267 E aromatic amino acid transport protein AroP K03293
CNPNMHOP_01727 2.7e-188 ansA 3.5.1.1 EJ Asparaginase
CNPNMHOP_01728 0.0 cadA P E1-E2 ATPase
CNPNMHOP_01729 1.6e-221 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
CNPNMHOP_01730 4.1e-264 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CNPNMHOP_01732 5.1e-11 XK27_10430 S NAD(P)H-binding
CNPNMHOP_01733 1.5e-159 yicL EG EamA-like transporter family
CNPNMHOP_01734 6e-194 pldB 3.1.1.5 I Serine aminopeptidase, S33
CNPNMHOP_01735 3.2e-113 K helix_turn_helix, Lux Regulon
CNPNMHOP_01736 5.4e-226 2.7.13.3 T Histidine kinase
CNPNMHOP_01737 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
CNPNMHOP_01738 1.2e-131 fhaA T Protein of unknown function (DUF2662)
CNPNMHOP_01739 5.2e-71 fhaB T Inner membrane component of T3SS, cytoplasmic domain
CNPNMHOP_01740 1.3e-240 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
CNPNMHOP_01741 1.3e-271 rodA D Belongs to the SEDS family
CNPNMHOP_01742 8e-266 pbpA M penicillin-binding protein
CNPNMHOP_01743 5.8e-177 T Protein tyrosine kinase
CNPNMHOP_01744 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
CNPNMHOP_01745 1.7e-119 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
CNPNMHOP_01746 1.3e-207 srtA 3.4.22.70 M Sortase family
CNPNMHOP_01747 2.9e-137 S Bacterial protein of unknown function (DUF881)
CNPNMHOP_01748 3.1e-57 crgA D Involved in cell division
CNPNMHOP_01749 1.3e-241 L ribosomal rna small subunit methyltransferase
CNPNMHOP_01750 3.4e-146 gluP 3.4.21.105 S Rhomboid family
CNPNMHOP_01751 3.4e-35
CNPNMHOP_01752 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CNPNMHOP_01753 6.3e-63 I Sterol carrier protein
CNPNMHOP_01754 4.9e-42 S Protein of unknown function (DUF3073)
CNPNMHOP_01755 2.2e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
CNPNMHOP_01756 6.1e-299 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNPNMHOP_01757 0.0 yjjP S Threonine/Serine exporter, ThrE
CNPNMHOP_01758 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CNPNMHOP_01759 1.1e-38
CNPNMHOP_01760 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CNPNMHOP_01761 1e-240 ytfL P Transporter associated domain
CNPNMHOP_01762 2.5e-186 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CNPNMHOP_01763 8.9e-101 S Protein of unknown function DUF45
CNPNMHOP_01767 2.5e-57 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CNPNMHOP_01768 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CNPNMHOP_01769 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
CNPNMHOP_01770 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNPNMHOP_01771 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNPNMHOP_01772 5.3e-89 S Protein of unknown function (DUF721)
CNPNMHOP_01773 2.4e-234 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CNPNMHOP_01774 2.5e-203 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CNPNMHOP_01775 2.9e-306 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CNPNMHOP_01776 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
CNPNMHOP_01777 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
CNPNMHOP_01778 3.6e-91 jag S Putative single-stranded nucleic acids-binding domain
CNPNMHOP_01779 1.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
CNPNMHOP_01780 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
CNPNMHOP_01781 1.7e-201 parB K Belongs to the ParB family
CNPNMHOP_01782 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CNPNMHOP_01783 7e-14 S Psort location Extracellular, score 8.82
CNPNMHOP_01785 5.2e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
CNPNMHOP_01786 2e-12 S Domain of unknown function (DUF4143)
CNPNMHOP_01787 0.0 murJ KLT MviN-like protein
CNPNMHOP_01788 4.1e-306 murJ KLT MviN-like protein
CNPNMHOP_01789 0.0 M Conserved repeat domain
CNPNMHOP_01790 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
CNPNMHOP_01791 3.2e-283 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
CNPNMHOP_01792 2.6e-109 S LytR cell envelope-related transcriptional attenuator
CNPNMHOP_01793 8.1e-168 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CNPNMHOP_01794 6e-166 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CNPNMHOP_01795 1.6e-197 S G5
CNPNMHOP_01797 7.5e-151 O Thioredoxin
CNPNMHOP_01798 0.0 KLT Protein tyrosine kinase
CNPNMHOP_01799 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
CNPNMHOP_01800 1.8e-83 K Cro/C1-type HTH DNA-binding domain
CNPNMHOP_01801 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
CNPNMHOP_01802 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
CNPNMHOP_01803 2.5e-116 S Short repeat of unknown function (DUF308)
CNPNMHOP_01804 2.3e-48 S Antitoxin component of a toxin-antitoxin (TA) module
CNPNMHOP_01805 7.5e-55 DJ Addiction module toxin, RelE StbE family
CNPNMHOP_01806 4.5e-13 S Psort location Extracellular, score 8.82
CNPNMHOP_01807 2.1e-230 EGP Major facilitator Superfamily
CNPNMHOP_01808 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNPNMHOP_01809 2e-269 KLT Domain of unknown function (DUF4032)
CNPNMHOP_01810 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
CNPNMHOP_01811 2.8e-131 K LytTr DNA-binding domain
CNPNMHOP_01812 2.7e-234 T GHKL domain
CNPNMHOP_01813 2.6e-51
CNPNMHOP_01814 1.8e-216 clcA_2 P Voltage gated chloride channel
CNPNMHOP_01815 8.8e-48 S Psort location Cytoplasmic, score
CNPNMHOP_01816 9.9e-138
CNPNMHOP_01817 5.3e-165 3.4.22.70 M Sortase family
CNPNMHOP_01818 1.4e-303 M LPXTG-motif cell wall anchor domain protein
CNPNMHOP_01819 0.0 S LPXTG-motif cell wall anchor domain protein
CNPNMHOP_01820 2.5e-10 S LPXTG-motif cell wall anchor domain protein
CNPNMHOP_01821 1.3e-72 S GtrA-like protein
CNPNMHOP_01822 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
CNPNMHOP_01823 2.2e-120 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
CNPNMHOP_01824 6.9e-80 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
CNPNMHOP_01825 3.4e-112 vex2 V ABC transporter, ATP-binding protein
CNPNMHOP_01826 8.5e-213 vex1 V Efflux ABC transporter, permease protein
CNPNMHOP_01827 8.3e-241 vex3 V ABC transporter permease
CNPNMHOP_01828 1.2e-34 lacS G Psort location CytoplasmicMembrane, score 10.00
CNPNMHOP_01829 1.7e-42 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
CNPNMHOP_01830 1.8e-227 yhjX EGP Major facilitator Superfamily
CNPNMHOP_01831 5.4e-309 trxB1 1.8.1.9 C Thioredoxin domain
CNPNMHOP_01832 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
CNPNMHOP_01833 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
CNPNMHOP_01834 5.9e-154 ypfH S Phospholipase/Carboxylesterase
CNPNMHOP_01835 0.0 yjcE P Sodium/hydrogen exchanger family
CNPNMHOP_01836 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CNPNMHOP_01837 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
CNPNMHOP_01838 1.5e-230 nagC GK ROK family
CNPNMHOP_01839 1.5e-244 msmE7 G Bacterial extracellular solute-binding protein
CNPNMHOP_01840 6.6e-157 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01841 2.6e-155 G Binding-protein-dependent transport system inner membrane component
CNPNMHOP_01842 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
CNPNMHOP_01843 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
CNPNMHOP_01844 9.8e-143 cobB2 K Sir2 family
CNPNMHOP_01845 7.4e-30 I alpha/beta hydrolase fold
CNPNMHOP_01846 3e-141 I alpha/beta hydrolase fold

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)