ORF_ID e_value Gene_name EC_number CAZy COGs Description
CFDECGKC_00002 5.6e-129 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CFDECGKC_00003 7.8e-188 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CFDECGKC_00004 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CFDECGKC_00005 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CFDECGKC_00006 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CFDECGKC_00007 3.7e-186 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CFDECGKC_00008 3.6e-181 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
CFDECGKC_00009 3.5e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CFDECGKC_00010 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CFDECGKC_00011 1.3e-99 2.3.1.128 K Acetyltransferase GNAT Family
CFDECGKC_00012 2.6e-280 S Protein of unknown function (DUF3114)
CFDECGKC_00014 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
CFDECGKC_00015 1.1e-298 V abc transporter atp-binding protein
CFDECGKC_00016 0.0 V abc transporter atp-binding protein
CFDECGKC_00017 4.4e-190 XK27_10075 S abc transporter atp-binding protein
CFDECGKC_00018 1.7e-10
CFDECGKC_00020 2.1e-70 M Pilin isopeptide linkage domain protein
CFDECGKC_00023 7.4e-74 XK27_04435 3.5.4.5 J Acetyltransferase GNAT family
CFDECGKC_00024 5.5e-141 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDECGKC_00025 7.1e-30
CFDECGKC_00026 8.7e-25 K trisaccharide binding
CFDECGKC_00027 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CFDECGKC_00028 2.3e-156 dprA LU DNA protecting protein DprA
CFDECGKC_00029 1e-165 GK ROK family
CFDECGKC_00030 1.3e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDECGKC_00031 9.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CFDECGKC_00032 5.3e-127 K DNA-binding helix-turn-helix protein
CFDECGKC_00033 6e-91 niaR S small molecule binding protein (contains 3H domain)
CFDECGKC_00034 1.3e-85
CFDECGKC_00035 3.8e-274 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CFDECGKC_00036 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CFDECGKC_00037 2.7e-126 gntR1 K transcriptional
CFDECGKC_00038 2.3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CFDECGKC_00039 2.3e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDECGKC_00040 9.4e-189 adhP 1.1.1.1 C alcohol dehydrogenase
CFDECGKC_00041 1e-44
CFDECGKC_00042 5.8e-51
CFDECGKC_00043 9.7e-269 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDECGKC_00044 2.1e-157 aatB ET ABC transporter substrate-binding protein
CFDECGKC_00045 4.4e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFDECGKC_00046 1.4e-105 artQ P ABC transporter (Permease
CFDECGKC_00047 1.9e-58 phnA P Alkylphosphonate utilization operon protein PhnA
CFDECGKC_00048 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CFDECGKC_00049 2.2e-165 cpsY K Transcriptional regulator
CFDECGKC_00050 6e-126 mur1 3.4.17.14, 3.5.1.28 NU muramidase
CFDECGKC_00051 2.4e-168 yeiH S Membrane
CFDECGKC_00053 3.4e-09
CFDECGKC_00054 1.6e-285 adcA P Belongs to the bacterial solute-binding protein 9 family
CFDECGKC_00055 3.9e-145 XK27_10720 D peptidase activity
CFDECGKC_00056 2e-274 pepD E Dipeptidase
CFDECGKC_00057 2.2e-160 whiA K May be required for sporulation
CFDECGKC_00058 3.1e-181 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CFDECGKC_00059 2e-163 rapZ S Displays ATPase and GTPase activities
CFDECGKC_00060 1.4e-136 yejC S cyclic nucleotide-binding protein
CFDECGKC_00061 9.9e-187 D nuclear chromosome segregation
CFDECGKC_00062 7.4e-80 hmpT S cog cog4720
CFDECGKC_00063 3.1e-136 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
CFDECGKC_00064 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CFDECGKC_00065 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CFDECGKC_00066 1.1e-301 dnaK O Heat shock 70 kDa protein
CFDECGKC_00067 6.3e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CFDECGKC_00068 1.4e-184 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CFDECGKC_00069 7.2e-101 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
CFDECGKC_00070 5.3e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CFDECGKC_00071 5.2e-130 ais G Phosphoglycerate mutase
CFDECGKC_00072 3.9e-243 XK27_08635 S UPF0210 protein
CFDECGKC_00073 1e-38 gcvR T UPF0237 protein
CFDECGKC_00074 1.5e-233 capA M Bacterial capsule synthesis protein
CFDECGKC_00075 2e-149 srtB 3.4.22.70 S Sortase family
CFDECGKC_00077 4.5e-29 K Helix-turn-helix domain
CFDECGKC_00078 1.8e-19
CFDECGKC_00079 4.5e-55 cadC K Bacterial regulatory protein, arsR family
CFDECGKC_00080 1.2e-101 cadD P cadmium resistance
CFDECGKC_00082 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CFDECGKC_00083 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CFDECGKC_00084 5.1e-22 K Transcriptional
CFDECGKC_00086 3.2e-150 degV S DegV family
CFDECGKC_00087 2.7e-91 yacP S RNA-binding protein containing a PIN domain
CFDECGKC_00088 3.7e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDECGKC_00090 3.6e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CFDECGKC_00091 3.1e-256 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFDECGKC_00093 3.3e-112 cysE 2.3.1.30 E serine acetyltransferase
CFDECGKC_00094 4.7e-140 S SseB protein N-terminal domain
CFDECGKC_00095 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CFDECGKC_00096 2.8e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFDECGKC_00097 3.5e-230 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CFDECGKC_00098 0.0 clpC O Belongs to the ClpA ClpB family
CFDECGKC_00099 1.8e-75 ctsR K Belongs to the CtsR family
CFDECGKC_00100 1.6e-82 S Putative small multi-drug export protein
CFDECGKC_00101 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CFDECGKC_00102 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
CFDECGKC_00103 2.4e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
CFDECGKC_00104 1.7e-287 ahpF O alkyl hydroperoxide reductase
CFDECGKC_00106 5.4e-30 S reductase
CFDECGKC_00107 3.9e-72 badR K Transcriptional regulator, marr family
CFDECGKC_00108 1.2e-35 XK27_02060 S Transglycosylase associated protein
CFDECGKC_00109 3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CFDECGKC_00110 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDECGKC_00116 1.9e-223 L Transposase
CFDECGKC_00117 1.2e-25 WQ51_00785
CFDECGKC_00118 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CFDECGKC_00119 4.3e-214 ywbD 2.1.1.191 J Methyltransferase
CFDECGKC_00120 2.9e-117 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CFDECGKC_00121 2.2e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CFDECGKC_00122 2e-102 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFDECGKC_00123 6.3e-60 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CFDECGKC_00124 2.2e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CFDECGKC_00125 4.1e-206 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CFDECGKC_00126 4.2e-53 yheA S Belongs to the UPF0342 family
CFDECGKC_00127 5.3e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
CFDECGKC_00128 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CFDECGKC_00129 4.5e-80 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CFDECGKC_00130 1.6e-138 pheA 4.2.1.51 E Prephenate dehydratase
CFDECGKC_00131 7.8e-250 msrR K Transcriptional regulator
CFDECGKC_00132 8.4e-152 ydiA P C4-dicarboxylate transporter malic acid transport protein
CFDECGKC_00133 4.2e-200 I acyl-CoA dehydrogenase
CFDECGKC_00134 2e-97 mip S hydroperoxide reductase activity
CFDECGKC_00135 1.9e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDECGKC_00136 1.9e-46 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDECGKC_00137 2.5e-91 Q Nodulation protein S (NodS)
CFDECGKC_00138 3.5e-121 U COG COG3505 Type IV secretory pathway, VirD4 components
CFDECGKC_00139 1e-69 L Integrase core domain
CFDECGKC_00140 1.2e-07 K Psort location Cytoplasmic, score 8.87
CFDECGKC_00141 3.4e-56 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDECGKC_00142 3.1e-93
CFDECGKC_00144 2.4e-44
CFDECGKC_00145 1.1e-56 S ParE toxin of type II toxin-antitoxin system, parDE
CFDECGKC_00146 4.4e-130 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDECGKC_00147 6.7e-128 S Domain of unknown function (DUF4336)
CFDECGKC_00148 1.2e-200 yeaN P transporter
CFDECGKC_00149 3.2e-150 yitS S EDD domain protein, DegV family
CFDECGKC_00150 5.8e-95 XK27_08140 K Bacterial regulatory proteins, tetR family
CFDECGKC_00151 8.6e-99 ypgQ F HD superfamily hydrolase
CFDECGKC_00152 4.4e-128 S CAAX amino terminal protease family
CFDECGKC_00153 2.1e-109 cutC P Participates in the control of copper homeostasis
CFDECGKC_00155 5.4e-21 S Domain of unknown function (DUF4767)
CFDECGKC_00156 4.3e-282 norB P Major facilitator superfamily
CFDECGKC_00157 1.1e-92 tetR K transcriptional regulator
CFDECGKC_00158 1.3e-148 S Domain of unknown function (DUF4300)
CFDECGKC_00159 3.7e-126 V CAAX protease self-immunity
CFDECGKC_00160 2.3e-158 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CFDECGKC_00161 1.6e-132 fecE 3.6.3.34 HP ABC transporter
CFDECGKC_00162 3.2e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CFDECGKC_00163 9.3e-124 ybbA S Putative esterase
CFDECGKC_00164 3.7e-157 yegS 2.7.1.107 I Diacylglycerol kinase
CFDECGKC_00165 2.8e-172 S Domain of unknown function (DUF389)
CFDECGKC_00166 5.5e-31 S Membrane
CFDECGKC_00167 7.8e-10 S CsbD-like
CFDECGKC_00168 1.6e-172 pdhD 1.8.1.4 C Dehydrogenase
CFDECGKC_00169 8.1e-167 acoA C Acetoin dehydrogenase E1 component subunit alpha
CFDECGKC_00170 4.6e-175 acoB C dehydrogenase E1 component
CFDECGKC_00171 2.1e-142 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDECGKC_00172 1.8e-83 Q Methyltransferase domain
CFDECGKC_00173 4.2e-77 K TetR family transcriptional regulator
CFDECGKC_00174 8.4e-48
CFDECGKC_00175 5.9e-124 V CAAX protease self-immunity
CFDECGKC_00176 1.5e-10
CFDECGKC_00177 8.4e-19 S Bacterial lipoprotein
CFDECGKC_00178 1.9e-60 S Protein of unknown function (DUF1722)
CFDECGKC_00179 2.6e-64 yqeB S Pyrimidine dimer DNA glycosylase
CFDECGKC_00181 2.5e-51
CFDECGKC_00182 6.8e-94 S CAAX protease self-immunity
CFDECGKC_00183 4.9e-119 estA E GDSL-like Lipase/Acylhydrolase
CFDECGKC_00184 1.1e-102
CFDECGKC_00185 2.1e-286 sulP P Sulfate permease and related transporters (MFS superfamily)
CFDECGKC_00186 9.9e-149 ycgQ S TIGR03943 family
CFDECGKC_00187 1.9e-156 XK27_03015 S permease
CFDECGKC_00189 0.0 yhgF K Transcriptional accessory protein
CFDECGKC_00190 9.3e-85 ydcK S Belongs to the SprT family
CFDECGKC_00191 2.9e-41 pspC KT PspC domain
CFDECGKC_00192 3.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CFDECGKC_00193 3.1e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CFDECGKC_00194 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CFDECGKC_00195 3e-67 ytxH S General stress protein
CFDECGKC_00197 7.5e-177 yegQ O Peptidase U32
CFDECGKC_00198 1.9e-250 yegQ O Peptidase U32
CFDECGKC_00199 6e-86 bioY S biotin synthase
CFDECGKC_00201 1.1e-33 XK27_12190 S protein conserved in bacteria
CFDECGKC_00202 2.8e-97 mntH P H( )-stimulated, divalent metal cation uptake system
CFDECGKC_00203 1e-96 mntH P H( )-stimulated, divalent metal cation uptake system
CFDECGKC_00204 4.2e-128 L NgoFVII restriction endonuclease
CFDECGKC_00205 3e-165 dcm 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
CFDECGKC_00206 8e-170 dcm_2 2.1.1.37 L C-5 cytosine-specific DNA methylase
CFDECGKC_00207 4.7e-08 K Psort location Cytoplasmic, score
CFDECGKC_00208 4.2e-15
CFDECGKC_00209 8.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CFDECGKC_00210 4.3e-138 M LysM domain
CFDECGKC_00211 8.4e-23
CFDECGKC_00212 5.2e-175 S hydrolase
CFDECGKC_00214 7.3e-115 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
CFDECGKC_00215 7.9e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CFDECGKC_00216 3.5e-139 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
CFDECGKC_00217 1.3e-26 P Hemerythrin HHE cation binding domain protein
CFDECGKC_00218 1.2e-152 5.2.1.8 G hydrolase
CFDECGKC_00219 6.1e-114 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDECGKC_00220 1.2e-200 MA20_36090 S Protein of unknown function (DUF2974)
CFDECGKC_00221 7.4e-130 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDECGKC_00222 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
CFDECGKC_00223 2.3e-15
CFDECGKC_00224 0.0
CFDECGKC_00225 8.2e-123 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
CFDECGKC_00226 7.5e-56 S Phage derived protein Gp49-like (DUF891)
CFDECGKC_00227 1e-42 K Helix-turn-helix domain
CFDECGKC_00228 3.6e-304 hsdM 2.1.1.72 V type I restriction-modification system
CFDECGKC_00229 1.3e-131 S double-stranded DNA endodeoxyribonuclease activity
CFDECGKC_00230 8.2e-33 2.4.1.21 GT5 M Right handed beta helix region
CFDECGKC_00231 1.8e-32 2.4.1.21 GT5 M Right handed beta helix region
CFDECGKC_00232 3.8e-174 spd F DNA RNA non-specific endonuclease
CFDECGKC_00233 7.7e-92 lemA S LemA family
CFDECGKC_00234 4e-135 htpX O Belongs to the peptidase M48B family
CFDECGKC_00235 5e-119 sirR K iron dependent repressor
CFDECGKC_00236 2.1e-171 sitA P Belongs to the bacterial solute-binding protein 9 family
CFDECGKC_00237 7.8e-133 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
CFDECGKC_00238 8.1e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
CFDECGKC_00239 7.6e-75 S Psort location CytoplasmicMembrane, score
CFDECGKC_00240 5.6e-65 S Domain of unknown function (DUF4430)
CFDECGKC_00241 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CFDECGKC_00242 3.5e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
CFDECGKC_00243 9.4e-112 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
CFDECGKC_00244 1.4e-163 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
CFDECGKC_00245 8.3e-106 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
CFDECGKC_00246 1.1e-89 dps P Belongs to the Dps family
CFDECGKC_00247 2.2e-78 perR P Belongs to the Fur family
CFDECGKC_00248 7.1e-27 yqgQ S protein conserved in bacteria
CFDECGKC_00249 2.7e-177 glk 2.7.1.2 G Glucokinase
CFDECGKC_00250 0.0 typA T GTP-binding protein TypA
CFDECGKC_00252 4.8e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CFDECGKC_00253 8e-199 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CFDECGKC_00254 2.2e-130 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CFDECGKC_00255 7.1e-224 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CFDECGKC_00256 4.7e-233 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CFDECGKC_00257 3e-122 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CFDECGKC_00258 1.8e-99 sepF D cell septum assembly
CFDECGKC_00259 2.9e-30 yggT D integral membrane protein
CFDECGKC_00260 2.7e-143 ylmH S conserved protein, contains S4-like domain
CFDECGKC_00261 8.4e-138 divIVA D Cell division initiation protein
CFDECGKC_00262 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CFDECGKC_00263 8.6e-87 sigH K DNA-templated transcription, initiation
CFDECGKC_00264 5.8e-138 ykuT M mechanosensitive ion channel
CFDECGKC_00265 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CFDECGKC_00266 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CFDECGKC_00267 2.7e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CFDECGKC_00268 3.8e-84 XK27_03960 S Protein of unknown function (DUF3013)
CFDECGKC_00269 2.4e-77 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
CFDECGKC_00270 7.9e-82 XK27_02675 K Acetyltransferase GNAT Family
CFDECGKC_00271 1.3e-176 prmA J Ribosomal protein L11 methyltransferase
CFDECGKC_00272 2.3e-128 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CFDECGKC_00273 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CFDECGKC_00274 2e-82 nrdI F Belongs to the NrdI family
CFDECGKC_00275 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CFDECGKC_00276 3.7e-73 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CFDECGKC_00277 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
CFDECGKC_00278 8.7e-237 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CFDECGKC_00279 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CFDECGKC_00280 1.3e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
CFDECGKC_00281 1.7e-189 yhjX P Major Facilitator
CFDECGKC_00282 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CFDECGKC_00283 2.8e-84 V VanZ like family
CFDECGKC_00284 4.8e-181 D nuclear chromosome segregation
CFDECGKC_00285 2.2e-123 glnQ E abc transporter atp-binding protein
CFDECGKC_00286 1.3e-271 glnP P ABC transporter
CFDECGKC_00287 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CFDECGKC_00288 4.8e-18 S Protein of unknown function (DUF3021)
CFDECGKC_00289 2e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
CFDECGKC_00290 3e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
CFDECGKC_00291 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CFDECGKC_00292 1.2e-233 sufD O assembly protein SufD
CFDECGKC_00293 2.9e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CFDECGKC_00294 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
CFDECGKC_00295 2.9e-273 sufB O assembly protein SufB
CFDECGKC_00296 4.7e-26
CFDECGKC_00297 1e-156 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CFDECGKC_00298 6.2e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CFDECGKC_00299 1.6e-71 adcR K transcriptional
CFDECGKC_00300 8.7e-92 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
CFDECGKC_00301 9.6e-128 adcB P ABC transporter (Permease
CFDECGKC_00302 9.9e-161 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
CFDECGKC_00303 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_00304 3.1e-158 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
CFDECGKC_00305 4.8e-257 pgi 5.3.1.9 G Belongs to the GPI family
CFDECGKC_00306 3e-151 Z012_04635 K sequence-specific DNA binding
CFDECGKC_00307 5.7e-278 V ABC transporter
CFDECGKC_00308 6.1e-126 yeeN K transcriptional regulatory protein
CFDECGKC_00309 1.7e-46 yajC U protein transport
CFDECGKC_00310 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CFDECGKC_00311 9.3e-144 cdsA 2.7.7.41 S Belongs to the CDS family
CFDECGKC_00312 2.1e-230 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
CFDECGKC_00313 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CFDECGKC_00314 0.0 WQ51_06230 S ABC transporter
CFDECGKC_00315 1.4e-142 cmpC S abc transporter atp-binding protein
CFDECGKC_00316 1.1e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CFDECGKC_00317 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CFDECGKC_00319 5.5e-44
CFDECGKC_00320 7.6e-55 S TM2 domain
CFDECGKC_00321 1.8e-164 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFDECGKC_00322 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDECGKC_00323 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CFDECGKC_00324 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
CFDECGKC_00325 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
CFDECGKC_00326 1.2e-68 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
CFDECGKC_00327 1.3e-145 cof S Sucrose-6F-phosphate phosphohydrolase
CFDECGKC_00328 1.3e-134 glcR K transcriptional regulator (DeoR family)
CFDECGKC_00329 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CFDECGKC_00330 7.6e-74 K helix_turn_helix multiple antibiotic resistance protein
CFDECGKC_00331 2.5e-231 S COG1073 Hydrolases of the alpha beta superfamily
CFDECGKC_00332 6e-152 cylA V abc transporter atp-binding protein
CFDECGKC_00333 3.4e-128 cylB V ABC-2 type transporter
CFDECGKC_00334 7.6e-74 K COG3279 Response regulator of the LytR AlgR family
CFDECGKC_00335 8.9e-32 S Protein of unknown function (DUF3021)
CFDECGKC_00336 9.6e-124 mta K Transcriptional
CFDECGKC_00337 4.7e-120 yhcA V abc transporter atp-binding protein
CFDECGKC_00338 7.9e-217 macB_2 V FtsX-like permease family
CFDECGKC_00339 1.3e-271 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CFDECGKC_00340 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CFDECGKC_00341 1.3e-73 yhaI S Protein of unknown function (DUF805)
CFDECGKC_00342 1.7e-254 pepC 3.4.22.40 E aminopeptidase
CFDECGKC_00343 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDECGKC_00344 1.3e-108 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CFDECGKC_00345 2.4e-92 ypsA S Belongs to the UPF0398 family
CFDECGKC_00346 9.6e-50 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CFDECGKC_00347 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CFDECGKC_00348 3.4e-275 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
CFDECGKC_00349 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
CFDECGKC_00350 8.2e-22
CFDECGKC_00351 4.7e-257 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CFDECGKC_00352 2.2e-87 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
CFDECGKC_00353 2.5e-302 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CFDECGKC_00354 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CFDECGKC_00355 1e-165 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDECGKC_00356 2e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CFDECGKC_00357 3.9e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CFDECGKC_00358 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
CFDECGKC_00359 2.2e-101 ybhL S Belongs to the BI1 family
CFDECGKC_00360 1.9e-12 ycdA S Domain of unknown function (DUF4352)
CFDECGKC_00361 2.1e-243 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CFDECGKC_00362 1.8e-90 K transcriptional regulator
CFDECGKC_00363 1.6e-36 yneF S UPF0154 protein
CFDECGKC_00364 6.4e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CFDECGKC_00365 3.9e-184 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CFDECGKC_00366 5.1e-98 XK27_09740 S Phosphoesterase
CFDECGKC_00367 8.3e-87 ykuL S CBS domain
CFDECGKC_00368 6.1e-132 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
CFDECGKC_00369 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CFDECGKC_00370 9.1e-96 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CFDECGKC_00371 3.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFDECGKC_00372 1.8e-257 trkH P Cation transport protein
CFDECGKC_00373 2.2e-157 trkA P Potassium transporter peripheral membrane component
CFDECGKC_00374 1.3e-06 I mechanosensitive ion channel activity
CFDECGKC_00376 3.6e-17 L Transposase
CFDECGKC_00378 4.1e-30
CFDECGKC_00379 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CFDECGKC_00380 2.6e-83 comFC K competence protein
CFDECGKC_00381 1.5e-250 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CFDECGKC_00382 1e-108 yvyE 3.4.13.9 S YigZ family
CFDECGKC_00383 4.1e-167 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CFDECGKC_00384 2.3e-111 acuB S CBS domain
CFDECGKC_00385 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
CFDECGKC_00386 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
CFDECGKC_00387 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
CFDECGKC_00388 4.2e-145 livH E Belongs to the binding-protein-dependent transport system permease family
CFDECGKC_00389 1.7e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
CFDECGKC_00390 1.9e-46 ylbG S UPF0298 protein
CFDECGKC_00391 3.4e-74 ylbF S Belongs to the UPF0342 family
CFDECGKC_00392 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CFDECGKC_00393 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CFDECGKC_00394 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
CFDECGKC_00395 0.0 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
CFDECGKC_00396 2.5e-222 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CFDECGKC_00397 3.3e-200 metB 2.5.1.48, 4.4.1.8 E cystathionine
CFDECGKC_00398 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
CFDECGKC_00399 7.8e-289 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
CFDECGKC_00400 4.8e-271 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CFDECGKC_00402 2.6e-82 S Protein conserved in bacteria
CFDECGKC_00406 3.8e-33
CFDECGKC_00407 2.3e-16
CFDECGKC_00408 0.0 L helicase
CFDECGKC_00410 5.7e-142 XK27_08075 2.4.1.83 GT2 M glycosyl transferase family 2
CFDECGKC_00411 1.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CFDECGKC_00412 1.6e-80 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFDECGKC_00413 1.7e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CFDECGKC_00415 1e-122 XK27_01040 S Protein of unknown function (DUF1129)
CFDECGKC_00416 1e-168 corA P COG0598 Mg2 and Co2 transporters
CFDECGKC_00417 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CFDECGKC_00421 2.8e-32 blpT
CFDECGKC_00422 7e-187 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
CFDECGKC_00423 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
CFDECGKC_00424 1.2e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CFDECGKC_00425 1.7e-61 yqhY S protein conserved in bacteria
CFDECGKC_00426 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CFDECGKC_00427 9.2e-178 scrR K Transcriptional regulator
CFDECGKC_00428 2.3e-289 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
CFDECGKC_00429 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_00430 1.3e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
CFDECGKC_00431 4e-186 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFDECGKC_00433 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFDECGKC_00434 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFDECGKC_00435 9.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CFDECGKC_00436 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CFDECGKC_00437 1e-180 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CFDECGKC_00438 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CFDECGKC_00442 2.9e-31 yozG K Transcriptional regulator
CFDECGKC_00444 7.1e-178 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CFDECGKC_00445 9.4e-95 yebC M Membrane
CFDECGKC_00446 2.9e-310 KT response to antibiotic
CFDECGKC_00447 4.4e-74 XK27_02470 K LytTr DNA-binding domain protein
CFDECGKC_00448 7.5e-113 liaI S membrane
CFDECGKC_00449 1.7e-298 O MreB/Mbl protein
CFDECGKC_00451 3.8e-145 V Psort location CytoplasmicMembrane, score
CFDECGKC_00454 5.2e-14
CFDECGKC_00455 1.7e-235 dcuS 2.7.13.3 T protein histidine kinase activity
CFDECGKC_00456 2e-242 2.7.13.3 T protein histidine kinase activity
CFDECGKC_00457 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CFDECGKC_00458 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CFDECGKC_00459 3.4e-124 S Protein of unknown function (DUF554)
CFDECGKC_00460 8.9e-133 ecsA_2 V abc transporter atp-binding protein
CFDECGKC_00461 4.3e-273 XK27_00765
CFDECGKC_00462 1.3e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CFDECGKC_00463 7.9e-222 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CFDECGKC_00464 2.6e-54 yhaI J Membrane
CFDECGKC_00465 3.8e-61 yhaI J Protein of unknown function (DUF805)
CFDECGKC_00466 1.4e-35 yhaI J Protein of unknown function (DUF805)
CFDECGKC_00468 3.2e-96
CFDECGKC_00469 1.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CFDECGKC_00470 4e-45 ftsL D cell division protein FtsL
CFDECGKC_00471 0.0 ftsI 3.4.16.4 M penicillin-binding protein
CFDECGKC_00472 9.1e-116 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CFDECGKC_00473 7.2e-221 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CFDECGKC_00475 9.3e-256 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CFDECGKC_00476 2.6e-68 yutD J protein conserved in bacteria
CFDECGKC_00477 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CFDECGKC_00478 9.7e-89 XK27_09885 V Glycopeptide antibiotics resistance protein
CFDECGKC_00481 0.0 mdlA V abc transporter atp-binding protein
CFDECGKC_00482 0.0 mdlB V abc transporter atp-binding protein
CFDECGKC_00483 4e-10 S Bacteriocin class II with double-glycine leader peptide
CFDECGKC_00488 3e-07
CFDECGKC_00489 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
CFDECGKC_00490 5.7e-163 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
CFDECGKC_00491 5e-98 V CAAX protease self-immunity
CFDECGKC_00492 2.7e-140 cppA E CppA N-terminal
CFDECGKC_00493 5.7e-172 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
CFDECGKC_00495 1.1e-75 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDECGKC_00496 9.2e-144 cah 4.2.1.1 P carbonic anhydrase
CFDECGKC_00497 0.0 pflB 2.3.1.54 C formate acetyltransferase'
CFDECGKC_00498 2e-200 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDECGKC_00499 3.6e-35
CFDECGKC_00501 1.5e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
CFDECGKC_00502 1e-162 yxeN P ABC transporter (Permease
CFDECGKC_00503 2.1e-129 tcyN 3.6.3.21 E abc transporter atp-binding protein
CFDECGKC_00504 5e-10 S Protein of unknown function (DUF4059)
CFDECGKC_00505 8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CFDECGKC_00506 1.3e-91 rsmD 2.1.1.171 L Methyltransferase
CFDECGKC_00507 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CFDECGKC_00508 9.3e-187 ylbL T Belongs to the peptidase S16 family
CFDECGKC_00509 5.4e-183 yhcC S radical SAM protein
CFDECGKC_00510 3.5e-97 ytqB J (SAM)-dependent
CFDECGKC_00512 0.0 yjcE P NhaP-type Na H and K H antiporters
CFDECGKC_00513 4.3e-141 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
CFDECGKC_00514 3.8e-238 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
CFDECGKC_00515 7.4e-10 MU outer membrane autotransporter barrel domain protein
CFDECGKC_00516 2e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFDECGKC_00518 1.2e-74 XK27_03180 T universal stress protein
CFDECGKC_00519 1.7e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
CFDECGKC_00520 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CFDECGKC_00521 4.1e-98 pncA Q isochorismatase
CFDECGKC_00522 5.8e-293 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDECGKC_00523 2.3e-218 M lipopolysaccharide 3-alpha-galactosyltransferase activity
CFDECGKC_00524 1.1e-145 H COG0463 Glycosyltransferases involved in cell wall biogenesis
CFDECGKC_00525 3.8e-187 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CFDECGKC_00526 1.7e-236 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CFDECGKC_00527 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDECGKC_00528 2.2e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CFDECGKC_00529 1.7e-229 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CFDECGKC_00530 6.2e-61
CFDECGKC_00531 3.3e-189 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CFDECGKC_00532 2.7e-142 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CFDECGKC_00533 7.4e-97 yqeG S hydrolase of the HAD superfamily
CFDECGKC_00534 1.1e-214 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CFDECGKC_00535 7.7e-49 yhbY J RNA-binding protein
CFDECGKC_00536 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CFDECGKC_00537 1.4e-104 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CFDECGKC_00538 2.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CFDECGKC_00539 1.9e-138 yqeM Q Methyltransferase domain protein
CFDECGKC_00540 2.6e-197 ylbM S Belongs to the UPF0348 family
CFDECGKC_00541 3.4e-39 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
CFDECGKC_00542 3e-43 yoeB S Addiction module toxin, Txe YoeB family
CFDECGKC_00545 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
CFDECGKC_00547 1.6e-103
CFDECGKC_00549 4.1e-07
CFDECGKC_00550 2.3e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CFDECGKC_00551 1.9e-130 ecsA V abc transporter atp-binding protein
CFDECGKC_00552 2.4e-176 ecsB U Bacterial ABC transporter protein EcsB
CFDECGKC_00553 9.5e-91 ytmP 2.7.1.89 M Phosphotransferase
CFDECGKC_00554 3.4e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CFDECGKC_00556 2.2e-210 ytfP S Flavoprotein
CFDECGKC_00557 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFDECGKC_00558 6.8e-65 XK27_02560 S cog cog2151
CFDECGKC_00559 2.6e-41 WQ51_02910 S Protein of unknown function, DUF536
CFDECGKC_00560 6.4e-105 dnaQ 2.7.7.7 L DNA polymerase III
CFDECGKC_00561 1.5e-119 K transcriptional regulator, MerR family
CFDECGKC_00562 0.0 V ABC transporter (Permease
CFDECGKC_00563 1.9e-124 V abc transporter atp-binding protein
CFDECGKC_00565 1.2e-43 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CFDECGKC_00566 1.2e-46
CFDECGKC_00567 6.8e-47
CFDECGKC_00568 0.0 ctpE P E1-E2 ATPase
CFDECGKC_00569 1.2e-59
CFDECGKC_00570 1.8e-256 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CFDECGKC_00571 4e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
CFDECGKC_00572 7.9e-132 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CFDECGKC_00573 5.1e-99 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
CFDECGKC_00574 5.8e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CFDECGKC_00575 1.1e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CFDECGKC_00576 2.3e-162 EGP Major facilitator Superfamily
CFDECGKC_00577 1.3e-70 copY K Copper transport repressor, CopY TcrY family
CFDECGKC_00578 6.8e-54 copA 3.6.3.54 P P-type ATPase
CFDECGKC_00579 1.4e-30 copZ 2.7.7.77 P Heavy metal-associated domain protein
CFDECGKC_00580 7.1e-192 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CFDECGKC_00581 3e-114 papP P ABC transporter (Permease
CFDECGKC_00582 4.6e-107 P ABC transporter (Permease
CFDECGKC_00583 3.3e-155 cjaA ET ABC transporter substrate-binding protein
CFDECGKC_00587 5.9e-255 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CFDECGKC_00588 2.2e-114 ywaF S Integral membrane protein (intg_mem_TP0381)
CFDECGKC_00589 2.3e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CFDECGKC_00590 1.9e-193 yjbB G Permeases of the major facilitator superfamily
CFDECGKC_00591 7.8e-152 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
CFDECGKC_00592 1.7e-99 thiT S Thiamine transporter
CFDECGKC_00593 3.3e-62 yjqA S Bacterial PH domain
CFDECGKC_00594 7.4e-153 corA P CorA-like protein
CFDECGKC_00595 2.2e-245 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CFDECGKC_00596 1.5e-40 yazA L endonuclease containing a URI domain
CFDECGKC_00597 7.9e-140 yabB 2.1.1.223 L Methyltransferase
CFDECGKC_00598 3.5e-142 nodB3 G deacetylase
CFDECGKC_00599 9.8e-143 plsC 2.3.1.51 I Acyltransferase
CFDECGKC_00600 3.8e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
CFDECGKC_00601 0.0 comEC S Competence protein ComEC
CFDECGKC_00602 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDECGKC_00603 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
CFDECGKC_00604 3e-232 ytoI K transcriptional regulator containing CBS domains
CFDECGKC_00605 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
CFDECGKC_00606 3.3e-156 rbn E Belongs to the UPF0761 family
CFDECGKC_00607 1.7e-85 ccl S cog cog4708
CFDECGKC_00608 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CFDECGKC_00609 3.8e-182 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CFDECGKC_00611 3.5e-172 yfjR K regulation of single-species biofilm formation
CFDECGKC_00613 5.8e-72 S QueT transporter
CFDECGKC_00614 1.4e-158 xth 3.1.11.2 L exodeoxyribonuclease III
CFDECGKC_00616 3e-198 XK27_00915 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CFDECGKC_00617 2.2e-17 yjdB S Domain of unknown function (DUF4767)
CFDECGKC_00618 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
CFDECGKC_00619 1.9e-149 O protein import
CFDECGKC_00620 4.2e-122 agrA KT phosphorelay signal transduction system
CFDECGKC_00621 1.3e-211 2.7.13.3 T protein histidine kinase activity
CFDECGKC_00623 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CFDECGKC_00624 1.5e-36 ylqC L Belongs to the UPF0109 family
CFDECGKC_00625 1.1e-236 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CFDECGKC_00626 0.0 ydaO E amino acid
CFDECGKC_00627 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
CFDECGKC_00628 4.5e-146 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CFDECGKC_00629 2.4e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
CFDECGKC_00630 4.5e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CFDECGKC_00631 5.3e-81 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CFDECGKC_00632 2.1e-168 murB 1.3.1.98 M cell wall formation
CFDECGKC_00633 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
CFDECGKC_00634 2.4e-139 potB P ABC-type spermidine putrescine transport system, permease component I
CFDECGKC_00635 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
CFDECGKC_00636 2.4e-203 potD P spermidine putrescine ABC transporter
CFDECGKC_00637 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
CFDECGKC_00638 6.9e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
CFDECGKC_00639 7.3e-153 GK ROK family
CFDECGKC_00640 1.9e-208 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CFDECGKC_00641 2e-100 wecD M Acetyltransferase (GNAT) domain
CFDECGKC_00642 7.7e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CFDECGKC_00643 8.3e-74 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
CFDECGKC_00644 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
CFDECGKC_00646 5.9e-56 lrgA S Effector of murein hydrolase LrgA
CFDECGKC_00647 9.4e-116 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CFDECGKC_00648 3.5e-97 3.1.3.18 S IA, variant 1
CFDECGKC_00649 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDECGKC_00650 1.2e-297 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CFDECGKC_00651 1.4e-110 serB 3.1.3.3 E phosphoserine phosphatase
CFDECGKC_00652 8.5e-08 N PFAM Uncharacterised protein family UPF0150
CFDECGKC_00653 9.8e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
CFDECGKC_00655 3.5e-61 ycaO O OsmC-like protein
CFDECGKC_00656 1.9e-62 paaI Q protein possibly involved in aromatic compounds catabolism
CFDECGKC_00657 1.3e-09 O ADP-ribosylglycohydrolase
CFDECGKC_00658 4e-125 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFDECGKC_00660 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CFDECGKC_00661 1.7e-17 XK27_00735
CFDECGKC_00662 1.1e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFDECGKC_00663 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
CFDECGKC_00664 5.6e-164 S CAAX amino terminal protease family protein
CFDECGKC_00666 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CFDECGKC_00667 3.4e-83 MA20_25245 K Gnat family
CFDECGKC_00668 5.5e-115 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
CFDECGKC_00669 8.3e-84 mutT 3.6.1.55 F Nudix family
CFDECGKC_00670 1.6e-130 ET Belongs to the bacterial solute-binding protein 3 family
CFDECGKC_00671 1.8e-131 ET Belongs to the bacterial solute-binding protein 3 family
CFDECGKC_00672 2.9e-199 arcT 2.6.1.1 E Aminotransferase
CFDECGKC_00673 1e-129 gltS ET Belongs to the bacterial solute-binding protein 3 family
CFDECGKC_00674 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CFDECGKC_00675 9.9e-51 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CFDECGKC_00676 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CFDECGKC_00677 4e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CFDECGKC_00678 3.4e-55 yitW K metal-sulfur cluster biosynthetic enzyme
CFDECGKC_00679 3e-170 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CFDECGKC_00680 2.9e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CFDECGKC_00681 1.9e-124 ycbB S Glycosyl transferase family 2
CFDECGKC_00682 1.1e-45 XK27_09090 S Uncharacterized conserved protein (DUF2304)
CFDECGKC_00683 2.3e-216 amrA S polysaccharide biosynthetic process
CFDECGKC_00684 1.8e-128 2.7.8.12 M transferase activity, transferring glycosyl groups
CFDECGKC_00685 1.3e-141 S Predicted membrane protein (DUF2142)
CFDECGKC_00686 2.3e-215 rgpA GT4 M Domain of unknown function (DUF1972)
CFDECGKC_00687 4.2e-175 rgpB GT2 M Glycosyltransferase, group 2 family protein
CFDECGKC_00688 5.2e-142 rgpC GM Transport permease protein
CFDECGKC_00689 4e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CFDECGKC_00690 1.3e-182 rgpEc GT2 M Glycosyl transferase family 2
CFDECGKC_00691 0.0 rgpF M Rhamnan synthesis protein F
CFDECGKC_00692 8.5e-117 radC E Belongs to the UPF0758 family
CFDECGKC_00693 8.2e-128 puuD T peptidase C26
CFDECGKC_00694 1.9e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CFDECGKC_00695 8.2e-60 XK27_04120 S Putative amino acid metabolism
CFDECGKC_00696 1.5e-203 iscS 2.8.1.7 E Cysteine desulfurase
CFDECGKC_00697 4.8e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFDECGKC_00698 5.4e-101 yjbK S Adenylate cyclase
CFDECGKC_00699 1.8e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
CFDECGKC_00700 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CFDECGKC_00701 2.3e-170 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
CFDECGKC_00702 1e-176 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
CFDECGKC_00703 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CFDECGKC_00704 2.7e-311 amiA E ABC transporter, substrate-binding protein, family 5
CFDECGKC_00705 1.1e-275 amiC P ABC transporter (Permease
CFDECGKC_00706 3.8e-165 amiD P ABC transporter (Permease
CFDECGKC_00707 3.9e-201 oppD P Belongs to the ABC transporter superfamily
CFDECGKC_00708 4.7e-171 oppF P Belongs to the ABC transporter superfamily
CFDECGKC_00709 4.5e-130 V Psort location CytoplasmicMembrane, score
CFDECGKC_00710 4.1e-119 skfE V abc transporter atp-binding protein
CFDECGKC_00711 5.6e-62 yvoA_1 K Transcriptional
CFDECGKC_00712 2.6e-146 supH S overlaps another CDS with the same product name
CFDECGKC_00713 3.5e-146 XK27_02985 S overlaps another CDS with the same product name
CFDECGKC_00714 7e-195 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CFDECGKC_00715 8.8e-113 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CFDECGKC_00716 7.9e-46 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
CFDECGKC_00717 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CFDECGKC_00718 8.1e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CFDECGKC_00719 9.2e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CFDECGKC_00720 1.3e-134 stp 3.1.3.16 T phosphatase
CFDECGKC_00721 8.3e-292 prkC 2.7.11.1 KLT serine threonine protein kinase
CFDECGKC_00722 4.1e-104 kcsA P Ion transport protein
CFDECGKC_00723 2.5e-116 yvqF S Membrane
CFDECGKC_00724 2.8e-169 vraS 2.7.13.3 T Histidine kinase
CFDECGKC_00725 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDECGKC_00727 7.2e-53 bta 1.8.1.8 CO cell redox homeostasis
CFDECGKC_00728 1.8e-61 L thioesterase
CFDECGKC_00729 1.7e-142 S Macro domain protein
CFDECGKC_00730 5.3e-50 trxA O Belongs to the thioredoxin family
CFDECGKC_00731 7.2e-74 yccU S CoA-binding protein
CFDECGKC_00732 1.2e-143 tatD L Hydrolase, tatd
CFDECGKC_00733 1.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CFDECGKC_00734 1.9e-153 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CFDECGKC_00736 3.5e-160 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CFDECGKC_00737 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CFDECGKC_00738 2.9e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
CFDECGKC_00739 1.6e-169 rmuC S RmuC domain protein
CFDECGKC_00740 3.1e-178 cbf S 3'-5' exoribonuclease yhaM
CFDECGKC_00741 4e-142 purR 2.4.2.7 F operon repressor
CFDECGKC_00742 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CFDECGKC_00743 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CFDECGKC_00744 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CFDECGKC_00745 1.9e-186 gap 1.2.1.12 C Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CFDECGKC_00746 1.2e-121
CFDECGKC_00747 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CFDECGKC_00748 3e-87 S Fusaric acid resistance protein-like
CFDECGKC_00749 2.5e-62 glnR K Transcriptional regulator
CFDECGKC_00750 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
CFDECGKC_00751 3.6e-114 pscB M CHAP domain protein
CFDECGKC_00753 4.3e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
CFDECGKC_00754 2.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CFDECGKC_00755 4.2e-95 S Protein of unknown function (DUF1697)
CFDECGKC_00756 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CFDECGKC_00757 5.7e-172 clcA_2 P Chloride transporter, ClC family
CFDECGKC_00758 3.5e-134 yfeJ 6.3.5.2 F glutamine amidotransferase
CFDECGKC_00759 4e-130 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
CFDECGKC_00760 2e-248 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
CFDECGKC_00761 6.8e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
CFDECGKC_00762 1.7e-109 cps4C M biosynthesis protein
CFDECGKC_00763 2.2e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
CFDECGKC_00764 3.6e-252 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
CFDECGKC_00765 8.2e-221 rgpAc GT4 M group 1 family protein
CFDECGKC_00766 2.4e-209 wcoF M Glycosyltransferase, group 1 family protein
CFDECGKC_00767 1.2e-120 Z012_10770 M Domain of unknown function (DUF1919)
CFDECGKC_00768 4.8e-150
CFDECGKC_00769 8.5e-163 M Glycosyltransferase, group 2 family protein
CFDECGKC_00770 5.2e-160 M Glycosyltransferase like family 2
CFDECGKC_00771 4.8e-173
CFDECGKC_00772 5.7e-245 epsU S Polysaccharide biosynthesis protein
CFDECGKC_00773 1.8e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
CFDECGKC_00774 3e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
CFDECGKC_00775 1.5e-186 wbbI M transferase activity, transferring glycosyl groups
CFDECGKC_00777 2.6e-149 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CFDECGKC_00778 4.3e-109 pgm G Belongs to the phosphoglycerate mutase family
CFDECGKC_00779 6.3e-108 G Belongs to the phosphoglycerate mutase family
CFDECGKC_00780 1.4e-107 G Belongs to the phosphoglycerate mutase family
CFDECGKC_00781 1.8e-196 S hmm pf01594
CFDECGKC_00782 1.7e-284 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CFDECGKC_00783 4.9e-39 S granule-associated protein
CFDECGKC_00784 2.3e-287 S unusual protein kinase
CFDECGKC_00785 1.6e-98 estA E Lysophospholipase L1 and related esterases
CFDECGKC_00786 1e-156 rssA S Phospholipase, patatin family
CFDECGKC_00787 2.9e-182 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CFDECGKC_00788 2.8e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
CFDECGKC_00790 2.6e-214 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CFDECGKC_00791 1.9e-118 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CFDECGKC_00792 1.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CFDECGKC_00793 0.0 S the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_00794 6e-225 2.7.13.3 T protein histidine kinase activity
CFDECGKC_00795 1.4e-202 hpk9 2.7.13.3 T protein histidine kinase activity
CFDECGKC_00796 1.5e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
CFDECGKC_00797 1.9e-181 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CFDECGKC_00798 4e-211 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CFDECGKC_00799 0.0 lpdA 1.8.1.4 C Dehydrogenase
CFDECGKC_00800 0.0 3.5.1.28 NU amidase activity
CFDECGKC_00801 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
CFDECGKC_00802 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
CFDECGKC_00803 2.2e-146 ycdO P periplasmic lipoprotein involved in iron transport
CFDECGKC_00804 1.8e-231 ycdB P peroxidase
CFDECGKC_00805 3.1e-290 ywbL P COG0672 High-affinity Fe2 Pb2 permease
CFDECGKC_00806 3.2e-122 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CFDECGKC_00807 9.5e-23 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CFDECGKC_00808 4.7e-213 msmX P Belongs to the ABC transporter superfamily
CFDECGKC_00809 9.8e-152 malG P ABC transporter (Permease
CFDECGKC_00810 1.7e-249 malF P ABC transporter (Permease
CFDECGKC_00811 3.9e-229 malX G ABC transporter
CFDECGKC_00812 2.1e-156 malR K Transcriptional regulator
CFDECGKC_00813 3e-300 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
CFDECGKC_00814 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CFDECGKC_00815 9.8e-38
CFDECGKC_00816 1.9e-186 lplA 6.3.1.20 H Lipoate-protein ligase
CFDECGKC_00817 3e-193 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
CFDECGKC_00818 0.0 pepN 3.4.11.2 E aminopeptidase
CFDECGKC_00819 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
CFDECGKC_00820 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDECGKC_00821 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CFDECGKC_00822 1.3e-154 pstA P phosphate transport system permease
CFDECGKC_00823 1.9e-156 pstC P probably responsible for the translocation of the substrate across the membrane
CFDECGKC_00824 6.9e-156 pstS P phosphate
CFDECGKC_00825 6.7e-248 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
CFDECGKC_00826 1.7e-142 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
CFDECGKC_00827 1e-44 yktA S Belongs to the UPF0223 family
CFDECGKC_00828 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CFDECGKC_00829 4.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CFDECGKC_00830 2.1e-146 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CFDECGKC_00831 3.7e-241 XK27_04775 S hemerythrin HHE cation binding domain
CFDECGKC_00832 6.1e-35 M1-755 P Hemerythrin HHE cation binding domain protein
CFDECGKC_00833 4e-110 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
CFDECGKC_00834 3.6e-85 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CFDECGKC_00835 1.1e-136 S haloacid dehalogenase-like hydrolase
CFDECGKC_00836 3.3e-239 metY 2.5.1.49 E o-acetylhomoserine
CFDECGKC_00837 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CFDECGKC_00838 1.1e-240 agcS E (Alanine) symporter
CFDECGKC_00839 4.3e-245 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CFDECGKC_00840 9.2e-178 bglC K Transcriptional regulator
CFDECGKC_00841 1.6e-238 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
CFDECGKC_00843 6.4e-82 yecS P ABC transporter (Permease
CFDECGKC_00844 1.3e-148 yckB ET Belongs to the bacterial solute-binding protein 3 family
CFDECGKC_00845 1.4e-241 nylA 3.5.1.4 J Belongs to the amidase family
CFDECGKC_00846 4.4e-112 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CFDECGKC_00847 4.5e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CFDECGKC_00848 5.2e-127 csm6 S Psort location Cytoplasmic, score
CFDECGKC_00849 3.6e-136 csm6 S Psort location Cytoplasmic, score
CFDECGKC_00850 7e-203 csm5 L CRISPR-associated RAMP protein, Csm5 family
CFDECGKC_00851 5.4e-164 csm4 L CRISPR-associated RAMP protein, Csm4 family
CFDECGKC_00852 2.4e-116 csm3 L RAMP superfamily
CFDECGKC_00853 3.6e-61 csm2 L Pfam:DUF310
CFDECGKC_00854 0.0 csm1 S CRISPR-associated protein Csm1 family
CFDECGKC_00855 5.4e-130 cas6 S Pfam:DUF2276
CFDECGKC_00856 1e-51 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFDECGKC_00857 6.3e-99 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CFDECGKC_00858 6.4e-42 cas1 L maintenance of DNA repeat elements
CFDECGKC_00859 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CFDECGKC_00860 7.2e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CFDECGKC_00861 3e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
CFDECGKC_00862 1.7e-132 S TraX protein
CFDECGKC_00863 2.5e-308 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CFDECGKC_00864 1.3e-271 S Psort location CytoplasmicMembrane, score
CFDECGKC_00865 5.8e-88 V ABC transporter, ATP-binding protein
CFDECGKC_00866 1.9e-47
CFDECGKC_00867 1e-224 dinF V Mate efflux family protein
CFDECGKC_00868 1.3e-179 yclQ P ABC-type enterochelin transport system, periplasmic component
CFDECGKC_00869 0.0 V Type III restriction enzyme, res subunit
CFDECGKC_00870 3.2e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
CFDECGKC_00871 2.5e-133 2.4.2.3 F Phosphorylase superfamily
CFDECGKC_00872 1.1e-92 K LysR substrate binding domain
CFDECGKC_00873 7.5e-125 ltaE 4.1.2.48 E Beta-eliminating lyase
CFDECGKC_00874 8.8e-105 K Bacterial regulatory proteins, tetR family
CFDECGKC_00875 7.1e-179 ybhR V ABC transporter
CFDECGKC_00876 4.8e-123 ybhF_2 V abc transporter atp-binding protein
CFDECGKC_00877 1.4e-187 adhB 1.1.1.1, 1.1.1.14 E Zinc-binding dehydrogenase
CFDECGKC_00878 7.7e-197 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CFDECGKC_00879 1.7e-157 czcD P cation diffusion facilitator family transporter
CFDECGKC_00880 4.6e-100 K Transcriptional regulator, TetR family
CFDECGKC_00881 1.1e-70 S Protein of unknown function with HXXEE motif
CFDECGKC_00882 4.9e-46
CFDECGKC_00883 5.8e-72 L Transposase
CFDECGKC_00884 1.8e-73 S Fibronectin-binding repeat
CFDECGKC_00885 2.4e-254 S Signal peptide protein, YSIRK family
CFDECGKC_00886 2e-126 K response regulator
CFDECGKC_00887 1.2e-175 saeS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
CFDECGKC_00888 1.4e-147 cbiO2 P ABC transporter, ATP-binding protein
CFDECGKC_00889 1.1e-155 P abc transporter atp-binding protein
CFDECGKC_00890 3.7e-132 cbiQ P cobalt transport
CFDECGKC_00891 4.1e-91 2.7.7.65 T Psort location CytoplasmicMembrane, score
CFDECGKC_00892 1.5e-138 S Phenazine biosynthesis protein
CFDECGKC_00893 2.6e-92 tetR K transcriptional regulator
CFDECGKC_00894 7.3e-124 V abc transporter atp-binding protein
CFDECGKC_00895 0.0 V ABC transporter (Permease
CFDECGKC_00896 1.5e-109 magIII L Base excision DNA repair protein, HhH-GPD family
CFDECGKC_00897 1.9e-262 proWX P ABC transporter
CFDECGKC_00898 6e-129 proV E abc transporter atp-binding protein
CFDECGKC_00899 1e-168 C alcohol dehydrogenase
CFDECGKC_00900 1.3e-135 1.6.5.2 GM NmrA-like family
CFDECGKC_00901 1.2e-68 mgrA K Transcriptional regulator, MarR family
CFDECGKC_00902 1.5e-77 S Macro domain
CFDECGKC_00903 2.2e-95 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
CFDECGKC_00904 5.6e-42 C Pyridoxamine 5'-phosphate oxidase
CFDECGKC_00905 3e-133 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
CFDECGKC_00906 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CFDECGKC_00909 1.3e-232 L DNA binding domain of tn916 integrase
CFDECGKC_00910 1.8e-30 xis S Excisionase from transposon Tn916
CFDECGKC_00911 9.3e-36 S Helix-turn-helix domain
CFDECGKC_00912 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CFDECGKC_00913 2e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CFDECGKC_00914 9.7e-236 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CFDECGKC_00915 2.1e-233 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
CFDECGKC_00917 3e-60 divIC D Septum formation initiator
CFDECGKC_00918 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CFDECGKC_00919 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CFDECGKC_00920 3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CFDECGKC_00921 1.1e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CFDECGKC_00922 1.1e-29 yyzM S Protein conserved in bacteria
CFDECGKC_00923 2.7e-197 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CFDECGKC_00924 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CFDECGKC_00925 7.7e-135 parB K Belongs to the ParB family
CFDECGKC_00926 1e-205 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
CFDECGKC_00927 4.8e-85 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CFDECGKC_00928 2.4e-119 yoaK S Protein of unknown function (DUF1275)
CFDECGKC_00932 0.0 XK27_10405 S Bacterial membrane protein YfhO
CFDECGKC_00933 1.1e-305 ybiT S abc transporter atp-binding protein
CFDECGKC_00934 7.8e-152 yvjA S membrane
CFDECGKC_00935 1.2e-191 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CFDECGKC_00936 5.6e-275 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CFDECGKC_00937 5.5e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CFDECGKC_00938 4.9e-58 yaaA S S4 domain protein YaaA
CFDECGKC_00939 6.7e-229 ymfF S Peptidase M16
CFDECGKC_00940 5.6e-231 ymfH S Peptidase M16
CFDECGKC_00941 1.4e-129 S sequence-specific DNA binding
CFDECGKC_00942 4.1e-90 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CFDECGKC_00943 1.1e-150 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDECGKC_00944 6.2e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDECGKC_00945 2.8e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CFDECGKC_00946 1e-70 lytE M LysM domain protein
CFDECGKC_00947 8.4e-64 isaA GH23 M Immunodominant staphylococcal antigen A
CFDECGKC_00948 4.7e-311 S Bacterial membrane protein, YfhO
CFDECGKC_00949 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CFDECGKC_00950 5.4e-99 yvbG U UPF0056 membrane protein
CFDECGKC_00951 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CFDECGKC_00952 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CFDECGKC_00953 2.2e-73 rplI J binds to the 23S rRNA
CFDECGKC_00954 1e-246 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CFDECGKC_00955 1.8e-47 veg S Biofilm formation stimulator VEG
CFDECGKC_00956 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CFDECGKC_00957 1.9e-10
CFDECGKC_00958 5.4e-54 ypaA M Membrane
CFDECGKC_00959 9.3e-95 XK27_06935 K transcriptional regulator
CFDECGKC_00960 7.3e-160 XK27_06930 V domain protein
CFDECGKC_00961 4.4e-107 S Putative adhesin
CFDECGKC_00962 8.6e-62 XK27_06920 S Protein of unknown function (DUF1700)
CFDECGKC_00963 6.3e-54 K transcriptional regulator, PadR family
CFDECGKC_00964 7e-115 nudL L hydrolase
CFDECGKC_00968 1.6e-25 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDECGKC_00969 0.0
CFDECGKC_00970 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
CFDECGKC_00971 9.9e-141 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
CFDECGKC_00972 5.8e-162 T Diguanylate cyclase
CFDECGKC_00973 6.3e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CFDECGKC_00974 9.9e-61 fruR K transcriptional
CFDECGKC_00975 5.7e-25 L Transposase
CFDECGKC_00976 3e-62 tnp* 1.1.1.193 L An automated process has identified a potential problem with this gene model
CFDECGKC_00977 4.3e-183 KLT Protein tyrosine kinase
CFDECGKC_00978 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CFDECGKC_00979 1.5e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CFDECGKC_00980 3e-217 metE 2.1.1.14 E Methionine synthase
CFDECGKC_00981 4.3e-53 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_00982 4.6e-118 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_00983 9e-31 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_00984 2.5e-239 hisS 6.1.1.21 J histidyl-tRNA synthetase
CFDECGKC_00986 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
CFDECGKC_00987 1.9e-167 XK27_01785 S cog cog1284
CFDECGKC_00988 3.4e-124 yaaA S Belongs to the UPF0246 family
CFDECGKC_00989 8.2e-116 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
CFDECGKC_00990 2.4e-89 XK27_10930 K acetyltransferase
CFDECGKC_00991 1.7e-13
CFDECGKC_00992 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
CFDECGKC_00993 1.6e-291 ccs S the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_00994 3.2e-44 yrzB S Belongs to the UPF0473 family
CFDECGKC_00995 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CFDECGKC_00996 6.3e-44 yrzL S Belongs to the UPF0297 family
CFDECGKC_00997 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CFDECGKC_00998 1.1e-234 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
CFDECGKC_01000 1.6e-213 int L Belongs to the 'phage' integrase family
CFDECGKC_01001 1.4e-18 S Domain of unknown function (DUF3173)
CFDECGKC_01002 1.5e-156 L Replication initiation factor
CFDECGKC_01003 8e-88 K sequence-specific DNA binding
CFDECGKC_01004 2.5e-173 yeiH S membrane
CFDECGKC_01005 4.7e-197 ltrA S Low temperature requirement protein
CFDECGKC_01007 2.2e-90 adk 2.7.4.3 F topology modulation protein
CFDECGKC_01008 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CFDECGKC_01009 1.3e-78 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CFDECGKC_01010 9.7e-36 XK27_09805 S MORN repeat protein
CFDECGKC_01011 0.0 XK27_09800 I Acyltransferase
CFDECGKC_01012 3e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CFDECGKC_01013 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
CFDECGKC_01014 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CFDECGKC_01015 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
CFDECGKC_01016 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CFDECGKC_01017 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CFDECGKC_01018 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CFDECGKC_01019 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CFDECGKC_01020 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CFDECGKC_01021 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CFDECGKC_01022 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
CFDECGKC_01023 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CFDECGKC_01024 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CFDECGKC_01025 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CFDECGKC_01026 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CFDECGKC_01027 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CFDECGKC_01028 7.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CFDECGKC_01029 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CFDECGKC_01030 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CFDECGKC_01031 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CFDECGKC_01032 1.9e-23 rpmD J ribosomal protein l30
CFDECGKC_01033 5.7e-58 rplO J binds to the 23S rRNA
CFDECGKC_01034 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CFDECGKC_01035 7.3e-118 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CFDECGKC_01036 3.3e-80 S peptidoglycan catabolic process
CFDECGKC_01039 1.2e-07
CFDECGKC_01040 5.9e-22 S COG5546 Small integral membrane protein
CFDECGKC_01041 1.7e-62 S Pfam:Phage_holin_4_1
CFDECGKC_01042 6.7e-18
CFDECGKC_01043 1e-172 S peptidoglycan catabolic process
CFDECGKC_01044 2.1e-110
CFDECGKC_01045 3.9e-250 S transmembrane transport
CFDECGKC_01046 7.9e-112 S Bacteriophage Gp15 protein
CFDECGKC_01047 7.5e-24
CFDECGKC_01048 5.2e-72
CFDECGKC_01049 1.4e-66 S Minor capsid protein from bacteriophage
CFDECGKC_01050 9.4e-51 S Minor capsid protein
CFDECGKC_01051 5.5e-29 S Minor capsid protein
CFDECGKC_01052 5.4e-44
CFDECGKC_01054 7.9e-141 S peptidase activity
CFDECGKC_01055 5.6e-72 S Phage minor structural protein GP20
CFDECGKC_01056 1.9e-188 S Phage minor capsid protein 2
CFDECGKC_01057 3.5e-264 S Phage portal protein, SPP1 Gp6-like
CFDECGKC_01058 2.7e-225 S Pfam:Terminase_3C
CFDECGKC_01059 3.6e-46 L DNA packaging
CFDECGKC_01060 1.6e-30
CFDECGKC_01063 1.4e-46 S sequence-specific DNA binding
CFDECGKC_01065 6.6e-25 S Protein of unknown function (DUF1642)
CFDECGKC_01067 5.9e-11
CFDECGKC_01068 6e-49 S hydrolase activity, acting on ester bonds
CFDECGKC_01069 2.7e-200 S DNA primase
CFDECGKC_01070 6.1e-106 S Bifunctional DNA primase/polymerase, N-terminal
CFDECGKC_01071 8.2e-68 S Protein of unknown function (DUF669)
CFDECGKC_01072 2.6e-225 S helicase activity
CFDECGKC_01073 5.6e-124 S AAA domain
CFDECGKC_01074 9.7e-64 S Siphovirus Gp157
CFDECGKC_01076 2.6e-80 M Pilin isopeptide linkage domain protein
CFDECGKC_01078 2.6e-25
CFDECGKC_01080 9.7e-74 K Phage antirepressor protein
CFDECGKC_01082 1.5e-24
CFDECGKC_01083 9.8e-21
CFDECGKC_01084 2.6e-19 E Zn peptidase
CFDECGKC_01086 5.1e-207 S Phage integrase family
CFDECGKC_01087 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CFDECGKC_01088 4.3e-77 yueI S Protein of unknown function (DUF1694)
CFDECGKC_01089 6.2e-202 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CFDECGKC_01090 3.6e-199 yyaQ S YjbR
CFDECGKC_01091 2.4e-181 ccpA K Catabolite control protein A
CFDECGKC_01092 2.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
CFDECGKC_01093 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
CFDECGKC_01094 2.5e-112 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFDECGKC_01095 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
CFDECGKC_01096 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CFDECGKC_01097 2e-33 secG U Preprotein translocase subunit SecG
CFDECGKC_01098 3.6e-219 mdtG EGP Major facilitator Superfamily
CFDECGKC_01099 1.1e-101 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CFDECGKC_01100 1.3e-151 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CFDECGKC_01101 1.3e-165 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CFDECGKC_01102 2e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CFDECGKC_01103 4.6e-88 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CFDECGKC_01104 4.9e-151 licT K antiterminator
CFDECGKC_01105 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CFDECGKC_01106 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
CFDECGKC_01107 7.5e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CFDECGKC_01108 2.4e-153 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CFDECGKC_01109 8e-148 I Alpha/beta hydrolase family
CFDECGKC_01110 6.6e-08
CFDECGKC_01111 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
CFDECGKC_01112 9.1e-78 feoA P FeoA domain protein
CFDECGKC_01113 1.4e-130 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFDECGKC_01114 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
CFDECGKC_01115 1e-34 ykuJ S protein conserved in bacteria
CFDECGKC_01116 3.7e-182 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CFDECGKC_01117 0.0 clpE O Belongs to the ClpA ClpB family
CFDECGKC_01118 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CFDECGKC_01119 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
CFDECGKC_01120 1.3e-171 S oxidoreductase
CFDECGKC_01121 1.7e-229 murN 2.3.2.16 V FemAB family
CFDECGKC_01122 4.4e-118 M Pfam SNARE associated Golgi protein
CFDECGKC_01123 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
CFDECGKC_01126 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
CFDECGKC_01129 4.8e-16 S Protein of unknown function (DUF2969)
CFDECGKC_01130 1.1e-200 ilvE 2.6.1.42 E Aminotransferase
CFDECGKC_01131 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDECGKC_01132 2.4e-10
CFDECGKC_01134 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CFDECGKC_01135 2.3e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CFDECGKC_01136 4.8e-13 L Helix-hairpin-helix DNA-binding motif class 1
CFDECGKC_01137 2.2e-30 S Domain of unknown function (DUF1912)
CFDECGKC_01138 8.8e-173 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
CFDECGKC_01139 2.3e-251 mmuP E amino acid
CFDECGKC_01140 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
CFDECGKC_01141 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CFDECGKC_01142 9.7e-22
CFDECGKC_01143 4.9e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CFDECGKC_01144 8.5e-167 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CFDECGKC_01145 4.5e-211 mvaS 2.3.3.10 I synthase
CFDECGKC_01146 1.9e-223 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
CFDECGKC_01147 3e-78 K hmm pf08876
CFDECGKC_01148 5.2e-119 yqfA K protein, Hemolysin III
CFDECGKC_01149 4.1e-29 pspC KT PspC domain protein
CFDECGKC_01150 1e-201 S Protein of unknown function (DUF3114)
CFDECGKC_01151 1.4e-159 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CFDECGKC_01152 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CFDECGKC_01153 8.8e-10
CFDECGKC_01154 1.3e-246 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
CFDECGKC_01155 5.7e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
CFDECGKC_01156 0.0 U protein secretion
CFDECGKC_01157 7.7e-118 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CFDECGKC_01158 1.1e-24
CFDECGKC_01159 7.7e-97 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
CFDECGKC_01160 9.2e-256 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CFDECGKC_01161 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
CFDECGKC_01162 2.9e-51 S ABC-2 family transporter protein
CFDECGKC_01163 6.4e-151 V ABC transporter, ATP-binding protein
CFDECGKC_01164 2.3e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CFDECGKC_01165 8e-177 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
CFDECGKC_01166 1.6e-166 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
CFDECGKC_01167 3.9e-135 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
CFDECGKC_01168 1.7e-102 GBS0088 J protein conserved in bacteria
CFDECGKC_01169 2.6e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFDECGKC_01170 3e-142 E Alpha beta hydrolase
CFDECGKC_01173 4.4e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
CFDECGKC_01174 4e-220 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CFDECGKC_01175 1.2e-126 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CFDECGKC_01176 1.5e-113 S VIT family
CFDECGKC_01177 7.5e-138 deoD_1 2.4.2.3 F Phosphorylase superfamily
CFDECGKC_01178 2.6e-196 yceA S Belongs to the UPF0176 family
CFDECGKC_01179 2e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CFDECGKC_01180 6.6e-198 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CFDECGKC_01181 0.0 lmrA V abc transporter atp-binding protein
CFDECGKC_01182 0.0 mdlB V abc transporter atp-binding protein
CFDECGKC_01183 2.5e-273 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CFDECGKC_01184 4.5e-103 abiGI K Transcriptional regulator, AbiEi antitoxin
CFDECGKC_01185 7.3e-31 XK27_00530 M CHAP domain protein
CFDECGKC_01186 2e-26 S Antitoxin component of a toxin-antitoxin (TA) module
CFDECGKC_01188 4.5e-132 agrA KT Response regulator of the LytR AlgR family
CFDECGKC_01189 6.1e-225 2.7.13.3 T GHKL domain
CFDECGKC_01192 2.1e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CFDECGKC_01193 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CFDECGKC_01194 1.4e-202 V permease protein
CFDECGKC_01195 8.9e-122 macB V ABC transporter, ATP-binding protein
CFDECGKC_01196 2.6e-180 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CFDECGKC_01197 3.4e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
CFDECGKC_01198 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
CFDECGKC_01199 9.3e-211 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
CFDECGKC_01200 5e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CFDECGKC_01201 4.7e-222 pyrP F uracil Permease
CFDECGKC_01202 4.8e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CFDECGKC_01203 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CFDECGKC_01204 1.4e-75 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CFDECGKC_01205 9e-167 fhuR K transcriptional regulator (lysR family)
CFDECGKC_01207 1.2e-95
CFDECGKC_01208 5.8e-55 V ABC-2 type transporter
CFDECGKC_01209 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
CFDECGKC_01213 9.2e-141 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CFDECGKC_01214 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_01215 2.3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CFDECGKC_01216 1e-254 cycA E permease
CFDECGKC_01217 5e-38 ynzC S UPF0291 protein
CFDECGKC_01218 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CFDECGKC_01219 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CFDECGKC_01220 1.1e-218 S membrane
CFDECGKC_01221 2.9e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CFDECGKC_01222 1.5e-292 nptA P COG1283 Na phosphate symporter
CFDECGKC_01223 2.1e-114 3.4.17.14, 3.5.1.28 NU amidase activity
CFDECGKC_01224 4.5e-75 S Bacterial inner membrane protein
CFDECGKC_01225 7.1e-139 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
CFDECGKC_01226 1.3e-94 S HD domain
CFDECGKC_01227 2.3e-103 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
CFDECGKC_01228 1.9e-53 glnB K Belongs to the P(II) protein family
CFDECGKC_01229 4.3e-228 amt P Ammonium Transporter
CFDECGKC_01230 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CFDECGKC_01231 1.2e-54 yabA L Involved in initiation control of chromosome replication
CFDECGKC_01232 3.4e-133 yaaT S stage 0 sporulation protein
CFDECGKC_01233 3.9e-159 holB 2.7.7.7 L dna polymerase iii
CFDECGKC_01234 6.3e-111 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CFDECGKC_01236 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CFDECGKC_01237 2.6e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CFDECGKC_01238 1.6e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CFDECGKC_01239 2.7e-217 ftsW D Belongs to the SEDS family
CFDECGKC_01240 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CFDECGKC_01241 2.3e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CFDECGKC_01242 1e-38 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFDECGKC_01243 3.6e-87 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CFDECGKC_01244 5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CFDECGKC_01245 7.3e-84 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDECGKC_01246 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CFDECGKC_01247 2.1e-110 atpB C it plays a direct role in the translocation of protons across the membrane
CFDECGKC_01248 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CFDECGKC_01249 2.1e-39
CFDECGKC_01250 1.5e-95 E Pfam:DUF955
CFDECGKC_01251 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CFDECGKC_01252 6.6e-18
CFDECGKC_01253 3.6e-97 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CFDECGKC_01254 1.1e-101 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CFDECGKC_01255 3e-14 coiA 3.6.4.12 S Competence protein
CFDECGKC_01256 1.1e-14 T peptidase
CFDECGKC_01257 1.5e-150 rarD S Transporter
CFDECGKC_01258 7.7e-152 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CFDECGKC_01259 2.6e-236 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
CFDECGKC_01260 1.4e-132 yxkH G deacetylase
CFDECGKC_01261 1.9e-206 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CFDECGKC_01262 8.2e-126 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CFDECGKC_01263 8.6e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CFDECGKC_01264 9.4e-181 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CFDECGKC_01265 3.5e-219 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
CFDECGKC_01266 3.6e-140 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CFDECGKC_01267 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
CFDECGKC_01269 1.3e-187 2.7.13.3 T GHKL domain
CFDECGKC_01270 2.5e-127 agrA KT response regulator
CFDECGKC_01271 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
CFDECGKC_01274 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CFDECGKC_01275 3e-84 yxjI S LURP-one-related
CFDECGKC_01276 1.9e-166 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
CFDECGKC_01277 6.1e-120 yrrM 2.1.1.104 S O-Methyltransferase
CFDECGKC_01278 5.9e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
CFDECGKC_01279 0.0 pepF E oligoendopeptidase F
CFDECGKC_01280 6.4e-163 coiA 3.6.4.12 S Competence protein
CFDECGKC_01281 7.6e-86 L transposase activity
CFDECGKC_01282 2.9e-148 L Integrase core domain protein
CFDECGKC_01283 2.2e-263 2.7.13.3, 2.7.7.7, 5.4.99.21 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CFDECGKC_01284 1.8e-109 S CAAX amino terminal protease family protein
CFDECGKC_01285 4.7e-168 K transcriptional regulator (lysR family)
CFDECGKC_01286 6.4e-159 S reductase
CFDECGKC_01288 2.2e-31 L COG1943 Transposase and inactivated derivatives
CFDECGKC_01289 3.5e-85 L Protein of unknown function (DUF1524)
CFDECGKC_01290 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CFDECGKC_01294 2.4e-187 phoH T phosphate starvation-inducible protein PhoH
CFDECGKC_01295 1.3e-123 sip M LysM domain protein
CFDECGKC_01296 3.7e-34 yozE S Belongs to the UPF0346 family
CFDECGKC_01297 3.8e-159 cvfB S Protein conserved in bacteria
CFDECGKC_01298 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CFDECGKC_01299 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CFDECGKC_01300 3.6e-203 sptS 2.7.13.3 T Histidine kinase
CFDECGKC_01301 6.4e-117 T response regulator
CFDECGKC_01302 3.3e-112 2.7.6.5 S Region found in RelA / SpoT proteins
CFDECGKC_01303 7.4e-112 K Acetyltransferase (GNAT) family
CFDECGKC_01304 0.0 lmrA2 V abc transporter atp-binding protein
CFDECGKC_01305 0.0 lmrA1 V abc transporter atp-binding protein
CFDECGKC_01306 3.3e-74 K DNA-binding transcription factor activity
CFDECGKC_01307 6e-70 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
CFDECGKC_01308 2.4e-274 S Psort location CytoplasmicMembrane, score
CFDECGKC_01309 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
CFDECGKC_01310 6.1e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
CFDECGKC_01311 5.3e-128 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
CFDECGKC_01312 1.3e-26 U response to pH
CFDECGKC_01313 0.0 yfmR S abc transporter atp-binding protein
CFDECGKC_01314 3.9e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CFDECGKC_01315 5.7e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CFDECGKC_01316 5.6e-147 XK27_08360 S EDD domain protein, DegV family
CFDECGKC_01317 5e-63 WQ51_03320 S cog cog4835
CFDECGKC_01318 4.2e-132 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CFDECGKC_01319 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CFDECGKC_01320 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CFDECGKC_01321 6e-94 2.3.1.128 K acetyltransferase
CFDECGKC_01322 2e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CFDECGKC_01323 3.5e-293 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CFDECGKC_01324 6.3e-224 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CFDECGKC_01325 1.8e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
CFDECGKC_01327 2.3e-229 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CFDECGKC_01328 3.5e-260 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CFDECGKC_01329 0.0 fruA 2.7.1.202 G phosphotransferase system
CFDECGKC_01330 1.3e-165 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
CFDECGKC_01331 4e-112 fruR K transcriptional
CFDECGKC_01332 7.1e-207 rny D Endoribonuclease that initiates mRNA decay
CFDECGKC_01333 1.4e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CFDECGKC_01334 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CFDECGKC_01335 3.9e-159 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CFDECGKC_01336 5.4e-256 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CFDECGKC_01337 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CFDECGKC_01338 3.6e-53 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CFDECGKC_01339 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CFDECGKC_01340 1.8e-125 IQ reductase
CFDECGKC_01341 3e-162 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
CFDECGKC_01342 2.2e-171 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
CFDECGKC_01343 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFDECGKC_01344 1.1e-162 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CFDECGKC_01345 5.2e-72 marR K Transcriptional regulator, MarR family
CFDECGKC_01346 3.1e-139 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
CFDECGKC_01347 2.2e-111 S HAD hydrolase, family IA, variant 3
CFDECGKC_01348 2.4e-256 lysC 2.7.2.4 E Belongs to the aspartokinase family
CFDECGKC_01349 3e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
CFDECGKC_01350 3.8e-246 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CFDECGKC_01351 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
CFDECGKC_01352 7.8e-102 ygaC J Belongs to the UPF0374 family
CFDECGKC_01353 5.6e-104 S Domain of unknown function (DUF1803)
CFDECGKC_01354 1.9e-164 ppaC 3.6.1.1 C inorganic pyrophosphatase
CFDECGKC_01355 3e-40 L COG1943 Transposase and inactivated derivatives
CFDECGKC_01356 6.6e-189 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
CFDECGKC_01357 2.9e-99 yvdD 3.2.2.10 S Belongs to the LOG family
CFDECGKC_01358 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CFDECGKC_01359 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CFDECGKC_01360 8e-42 ylxQ J ribosomal protein
CFDECGKC_01361 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
CFDECGKC_01362 4e-199 nusA K Participates in both transcription termination and antitermination
CFDECGKC_01363 2.3e-81 rimP S Required for maturation of 30S ribosomal subunits
CFDECGKC_01364 2e-188 brpA K Transcriptional
CFDECGKC_01365 1.8e-90 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
CFDECGKC_01366 1.2e-76 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
CFDECGKC_01367 1.6e-247 pbuO S permease
CFDECGKC_01368 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CFDECGKC_01369 7.3e-135 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
CFDECGKC_01370 6.2e-169 manL 2.7.1.191 G pts system
CFDECGKC_01371 4.7e-135 manY G pts system
CFDECGKC_01372 5.1e-162 manN G PTS system mannose fructose sorbose family IID component
CFDECGKC_01373 7.7e-67 manO S Protein conserved in bacteria
CFDECGKC_01374 4.9e-174 manL 2.7.1.191 G pts system
CFDECGKC_01375 1.2e-117 manM G pts system
CFDECGKC_01376 1.6e-168 manN G PTS system mannose fructose sorbose family IID component
CFDECGKC_01377 2.5e-62 manO S protein conserved in bacteria
CFDECGKC_01378 8.9e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CFDECGKC_01379 1.3e-108
CFDECGKC_01380 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CFDECGKC_01381 4.4e-166 dnaI L Primosomal protein DnaI
CFDECGKC_01382 1e-215 dnaB L Replication initiation and membrane attachment
CFDECGKC_01383 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CFDECGKC_01384 3.9e-279 T PhoQ Sensor
CFDECGKC_01385 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDECGKC_01386 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
CFDECGKC_01387 2.6e-129 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
CFDECGKC_01388 2.1e-236 P COG0168 Trk-type K transport systems, membrane components
CFDECGKC_01389 8e-120 ktrA P COG0569 K transport systems, NAD-binding component
CFDECGKC_01390 4.5e-149 cbiQ P cobalt transport
CFDECGKC_01391 1e-309 ykoD P abc transporter atp-binding protein
CFDECGKC_01392 2e-92 S UPF0397 protein
CFDECGKC_01393 2.5e-155 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
CFDECGKC_01394 6.1e-211 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
CFDECGKC_01395 2.3e-98 metI P ABC transporter (Permease
CFDECGKC_01396 6.4e-188 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CFDECGKC_01397 2e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
CFDECGKC_01398 1.9e-164 metQ M Belongs to the NlpA lipoprotein family
CFDECGKC_01399 1.8e-137 ET ABC transporter substrate-binding protein
CFDECGKC_01400 4.5e-129 cbiO P ABC transporter
CFDECGKC_01401 3.2e-136 P cobalt transport protein
CFDECGKC_01402 1.3e-176 cbiM P biosynthesis protein CbiM
CFDECGKC_01403 5.2e-161 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CFDECGKC_01404 4.7e-111 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
CFDECGKC_01405 5.3e-130 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
CFDECGKC_01406 6.6e-78 ureE O enzyme active site formation
CFDECGKC_01407 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CFDECGKC_01408 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CFDECGKC_01409 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CFDECGKC_01410 2.6e-94 ureI S AmiS/UreI family transporter
CFDECGKC_01411 2.2e-241 S Domain of unknown function (DUF4173)
CFDECGKC_01412 5.4e-53 yhaI L Membrane
CFDECGKC_01413 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
CFDECGKC_01414 1.3e-138 K sequence-specific DNA binding
CFDECGKC_01415 1.3e-106 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
CFDECGKC_01416 3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CFDECGKC_01417 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CFDECGKC_01418 6.7e-42 bipA Q Transposase
CFDECGKC_01419 1.2e-103 L Transposase
CFDECGKC_01420 1.1e-90 L COG3547 Transposase and inactivated derivatives
CFDECGKC_01421 0.0 zmpB M signal peptide protein, YSIRK family
CFDECGKC_01422 0.0 GM domain, Protein
CFDECGKC_01423 5.1e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CFDECGKC_01424 0.0 sbcC L ATPase involved in DNA repair
CFDECGKC_01425 1e-140
CFDECGKC_01426 3.3e-36 S PFAM Uncharacterised protein family (UPF0153)
CFDECGKC_01427 0.0 M family 8
CFDECGKC_01428 2.8e-211 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
CFDECGKC_01429 1.3e-290 asp1 S Accessory Sec system protein Asp1
CFDECGKC_01430 2.9e-290 asp2 3.4.11.5 S Accessory Sec system protein Asp2
CFDECGKC_01431 1.5e-77 asp3 S Accessory Sec system protein Asp3
CFDECGKC_01432 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CFDECGKC_01433 2.8e-282 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
CFDECGKC_01434 2.3e-243 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
CFDECGKC_01435 2.6e-17 S Accessory secretory protein Sec Asp4
CFDECGKC_01436 3.6e-16 S Accessory secretory protein Sec, Asp5
CFDECGKC_01437 2.1e-185 nss M transferase activity, transferring glycosyl groups
CFDECGKC_01438 1.1e-201 pmrB EGP Major facilitator Superfamily
CFDECGKC_01439 2.8e-19
CFDECGKC_01440 8.4e-262 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CFDECGKC_01441 1.6e-211 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CFDECGKC_01442 1.1e-81 ypmB S Protein conserved in bacteria
CFDECGKC_01443 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CFDECGKC_01444 1.6e-117 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CFDECGKC_01445 2.7e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
CFDECGKC_01446 1.7e-180 yufP S Belongs to the binding-protein-dependent transport system permease family
CFDECGKC_01447 6.2e-277 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CFDECGKC_01448 1.4e-187 tcsA S membrane
CFDECGKC_01449 1.3e-66 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CFDECGKC_01450 2.7e-112 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CFDECGKC_01451 1.1e-231 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
CFDECGKC_01452 1.7e-105 rsmC 2.1.1.172 J Methyltransferase small domain protein
CFDECGKC_01453 1.2e-171 coaA 2.7.1.33 F Pantothenic acid kinase
CFDECGKC_01454 1e-29 rpsT J Binds directly to 16S ribosomal RNA
CFDECGKC_01455 9.8e-237 T PhoQ Sensor
CFDECGKC_01456 2.7e-120 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDECGKC_01457 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
CFDECGKC_01458 2.1e-115 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
CFDECGKC_01459 3.1e-90 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CFDECGKC_01460 1e-91 panT S ECF transporter, substrate-specific component
CFDECGKC_01461 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CFDECGKC_01462 1.6e-165 metF 1.5.1.20 E reductase
CFDECGKC_01463 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CFDECGKC_01465 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
CFDECGKC_01466 0.0 3.6.3.8 P cation transport ATPase
CFDECGKC_01467 5.3e-242 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CFDECGKC_01468 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDECGKC_01469 9.6e-236 dltB M Membrane protein involved in D-alanine export
CFDECGKC_01470 4.2e-297 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CFDECGKC_01471 0.0 XK27_10035 V abc transporter atp-binding protein
CFDECGKC_01472 2.2e-291 yfiB1 V abc transporter atp-binding protein
CFDECGKC_01473 1.1e-99 pvaA M lytic transglycosylase activity
CFDECGKC_01474 9.3e-178 ndpA S 37-kD nucleoid-associated bacterial protein
CFDECGKC_01475 3e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CFDECGKC_01476 9.4e-104 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CFDECGKC_01477 7.5e-144 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CFDECGKC_01478 3.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CFDECGKC_01479 7.8e-111 tdk 2.7.1.21 F thymidine kinase
CFDECGKC_01480 1.9e-181 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CFDECGKC_01481 2.1e-151 gst O Glutathione S-transferase
CFDECGKC_01482 6.5e-176 nrnA 3.1.13.3, 3.1.3.7 S domain protein
CFDECGKC_01483 1.1e-172 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
CFDECGKC_01484 4.4e-45 rpmE2 J 50S ribosomal protein L31
CFDECGKC_01485 4.7e-230 mntH P Mn2 and Fe2 transporters of the NRAMP family
CFDECGKC_01486 7.6e-164 ypuA S secreted protein
CFDECGKC_01487 8.2e-72 yaeR E COG0346 Lactoylglutathione lyase and related lyases
CFDECGKC_01488 9.3e-133 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
CFDECGKC_01489 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CFDECGKC_01490 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CFDECGKC_01491 7.8e-255 noxE P NADH oxidase
CFDECGKC_01492 2.1e-293 yfmM S abc transporter atp-binding protein
CFDECGKC_01493 3e-82 XK27_01265 S ECF-type riboflavin transporter, S component
CFDECGKC_01494 2.6e-155 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
CFDECGKC_01495 6.3e-85 S ECF-type riboflavin transporter, S component
CFDECGKC_01497 6.1e-238 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CFDECGKC_01498 1.2e-55 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
CFDECGKC_01500 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDECGKC_01501 4.3e-89 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CFDECGKC_01502 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CFDECGKC_01503 1e-22 WQ51_00220 K Helix-turn-helix domain
CFDECGKC_01504 2e-76 S Protein of unknown function (DUF3278)
CFDECGKC_01505 0.0 smc D Required for chromosome condensation and partitioning
CFDECGKC_01506 5.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CFDECGKC_01507 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CFDECGKC_01508 1.2e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CFDECGKC_01510 1.1e-294 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDECGKC_01511 6.5e-90 pat 2.3.1.183 M acetyltransferase
CFDECGKC_01512 4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CFDECGKC_01513 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CFDECGKC_01514 7e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
CFDECGKC_01515 7.2e-121 sdaAB 4.3.1.17 E L-serine dehydratase
CFDECGKC_01516 1.2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
CFDECGKC_01517 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
CFDECGKC_01518 1.5e-161 yjlA EG membrane
CFDECGKC_01519 1.1e-79 3.4.21.89 S RDD family
CFDECGKC_01520 2.8e-51
CFDECGKC_01521 5.9e-86
CFDECGKC_01522 2.3e-24
CFDECGKC_01523 6.6e-142 S ABC-2 family transporter protein
CFDECGKC_01524 9e-142 S ABC-2 family transporter protein
CFDECGKC_01525 7.2e-186 S abc transporter atp-binding protein
CFDECGKC_01526 5.6e-81
CFDECGKC_01529 4.3e-85 yfjR K regulation of single-species biofilm formation
CFDECGKC_01530 7.9e-126 S Protein of unknown function DUF262
CFDECGKC_01531 1.1e-201 S Protein of unknown function DUF262
CFDECGKC_01532 8.8e-102 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CFDECGKC_01533 1.2e-189 desK 2.7.13.3 T Histidine kinase
CFDECGKC_01534 5.8e-132 yvfS V ABC-2 type transporter
CFDECGKC_01535 2.5e-158 XK27_09825 V abc transporter atp-binding protein
CFDECGKC_01538 2.8e-171 fabH 2.3.1.180 I synthase III
CFDECGKC_01539 1.7e-240 6.2.1.30 H Coenzyme F390 synthetase
CFDECGKC_01540 4.7e-151 gumP S Metallo-beta-lactamase superfamily
CFDECGKC_01541 3.1e-181 ybjS 1.1.1.133, 5.1.3.13 M NAD dependent epimerase dehydratase family protein
CFDECGKC_01542 4.4e-228 2.4.1.276 GT1 CG Glycosyltransferase family 28 C-terminal domain
CFDECGKC_01543 1.3e-105 1.1.1.105 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDECGKC_01544 1.1e-169 ugcG 2.4.1.80 GT21 M transferase activity, transferring glycosyl groups
CFDECGKC_01545 2.4e-92
CFDECGKC_01546 7.9e-209 2.4.1.276 GT1 CG transferase activity, transferring hexosyl groups
CFDECGKC_01548 1.3e-193 anK3 G response to abiotic stimulus
CFDECGKC_01549 0.0 hscC O Belongs to the heat shock protein 70 family
CFDECGKC_01550 1.8e-165 yocS S Transporter
CFDECGKC_01551 5.8e-82 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
CFDECGKC_01552 1e-115 yvfS V Transporter
CFDECGKC_01553 1.1e-153 XK27_09825 V abc transporter atp-binding protein
CFDECGKC_01554 3.1e-15 liaI KT membrane
CFDECGKC_01555 2.6e-30 liaI KT membrane
CFDECGKC_01556 4.7e-93 XK27_05000 S Fe-S-cluster oxidoreductase
CFDECGKC_01557 0.0 V ABC transporter (permease)
CFDECGKC_01558 3.9e-131 macB2 V ABC transporter, ATP-binding protein
CFDECGKC_01559 1.1e-154 T Histidine kinase
CFDECGKC_01560 1.7e-122 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDECGKC_01561 3.7e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CFDECGKC_01562 1.1e-215 pbuX F xanthine permease
CFDECGKC_01563 7e-276 V (ABC) transporter
CFDECGKC_01564 8.9e-145 K sequence-specific DNA binding
CFDECGKC_01565 9.1e-232 norM V Multidrug efflux pump
CFDECGKC_01567 9.1e-178 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CFDECGKC_01568 4.4e-231 brnQ E Component of the transport system for branched-chain amino acids
CFDECGKC_01569 1.4e-178 manA 5.3.1.8 G mannose-6-phosphate isomerase
CFDECGKC_01570 1.8e-59 S Protein of unknown function (DUF3290)
CFDECGKC_01571 1.5e-107 S Protein of unknown function (DUF421)
CFDECGKC_01572 1.4e-16 csbD S CsbD-like
CFDECGKC_01573 1.6e-115 S Carbohydrate-binding domain-containing protein Cthe_2159
CFDECGKC_01574 6.4e-40 XK27_01300 P Protein conserved in bacteria
CFDECGKC_01575 7.2e-216 yfnA E amino acid
CFDECGKC_01576 0.0 S dextransucrase activity
CFDECGKC_01577 6.6e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CFDECGKC_01578 1.5e-42 S Sugar efflux transporter for intercellular exchange
CFDECGKC_01579 6.8e-204 P FtsX-like permease family
CFDECGKC_01580 4.6e-123 V abc transporter atp-binding protein
CFDECGKC_01581 2.8e-97 K WHG domain
CFDECGKC_01582 8e-171 ydhF S Aldo keto reductase
CFDECGKC_01584 5.5e-27 XK27_07105 K transcriptional
CFDECGKC_01585 9.4e-31
CFDECGKC_01586 1.4e-107 XK27_02070 S nitroreductase
CFDECGKC_01587 2e-152 1.13.11.2 S glyoxalase
CFDECGKC_01588 1.6e-76 ywnA K Transcriptional regulator
CFDECGKC_01589 1.2e-155 E Alpha/beta hydrolase of unknown function (DUF915)
CFDECGKC_01590 1.2e-225 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CFDECGKC_01591 1.2e-109 drgA C nitroreductase
CFDECGKC_01592 2.5e-97 yoaK S Protein of unknown function (DUF1275)
CFDECGKC_01593 1.3e-38 DJ nuclease activity
CFDECGKC_01594 1.2e-29 XK27_10490
CFDECGKC_01595 3e-156 yvgN C reductase
CFDECGKC_01596 3.2e-209 S Tetratricopeptide repeat
CFDECGKC_01597 0.0 lacL 3.2.1.23 G -beta-galactosidase
CFDECGKC_01598 0.0 lacS G transporter
CFDECGKC_01599 1.3e-198 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
CFDECGKC_01600 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFDECGKC_01601 1.3e-287 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CFDECGKC_01602 9e-220 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CFDECGKC_01603 1.7e-182 galR K Transcriptional regulator
CFDECGKC_01604 6e-307 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
CFDECGKC_01605 1.2e-217 vncS 2.7.13.3 T Histidine kinase
CFDECGKC_01606 7.8e-112 K Response regulator receiver domain protein
CFDECGKC_01607 5.8e-234 vex3 V Efflux ABC transporter, permease protein
CFDECGKC_01608 8.6e-108 vex2 V abc transporter atp-binding protein
CFDECGKC_01609 1.1e-212 vex1 V Efflux ABC transporter, permease protein
CFDECGKC_01610 1.9e-283 XK27_07020 S Belongs to the UPF0371 family
CFDECGKC_01612 1.3e-196 gldA 1.1.1.6 C glycerol dehydrogenase
CFDECGKC_01613 6.4e-105 XK27_10475 S oxidoreductase
CFDECGKC_01614 1.4e-47 XK27_10475 S oxidoreductase
CFDECGKC_01615 8.2e-58 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
CFDECGKC_01616 9e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
CFDECGKC_01617 4.5e-180 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
CFDECGKC_01618 2.8e-227 thrE K Psort location CytoplasmicMembrane, score
CFDECGKC_01619 2.4e-134 T Ser Thr phosphatase family protein
CFDECGKC_01620 9.4e-34 S Immunity protein 41
CFDECGKC_01621 0.0 pepO 3.4.24.71 O Peptidase family M13
CFDECGKC_01622 6.1e-09 S Enterocin A Immunity
CFDECGKC_01623 1.9e-192 mccF V LD-carboxypeptidase
CFDECGKC_01624 6.1e-15 S integral membrane protein
CFDECGKC_01625 4.2e-43 czrA K helix_turn_helix, Arsenical Resistance Operon Repressor
CFDECGKC_01626 2.8e-118 yhfC S Putative membrane peptidase family (DUF2324)
CFDECGKC_01627 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_01629 3.4e-227 S dextransucrase activity
CFDECGKC_01630 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_01631 0.0 S dextransucrase activity
CFDECGKC_01632 0.0 S dextransucrase activity
CFDECGKC_01633 1.2e-78 S dextransucrase activity
CFDECGKC_01634 0.0 S dextransucrase activity
CFDECGKC_01635 7.3e-101 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CFDECGKC_01636 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CFDECGKC_01637 0.0 M Putative cell wall binding repeat
CFDECGKC_01638 0.0 S dextransucrase activity
CFDECGKC_01639 0.0 S dextransucrase activity
CFDECGKC_01640 8.6e-18 S dextransucrase activity
CFDECGKC_01641 5.3e-84 M Putative cell wall binding repeat
CFDECGKC_01642 3.4e-224 S dextransucrase activity
CFDECGKC_01644 2.8e-226 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CFDECGKC_01645 3.4e-14 rpmH J Ribosomal protein L34
CFDECGKC_01646 5.9e-100 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
CFDECGKC_01647 9.3e-104 K Transcriptional regulator
CFDECGKC_01648 9.6e-173 jag S RNA-binding protein
CFDECGKC_01649 9.7e-147 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CFDECGKC_01650 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CFDECGKC_01651 3.3e-269 argH 4.3.2.1 E Argininosuccinate lyase
CFDECGKC_01652 5.8e-230 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CFDECGKC_01653 1.8e-128 fasA KT Response regulator of the LytR AlgR family
CFDECGKC_01654 8e-225 fasC 2.7.13.3 T protein histidine kinase activity
CFDECGKC_01655 2.4e-210 hpk9 2.7.13.3 T protein histidine kinase activity
CFDECGKC_01656 2.6e-150 hpk9 2.7.13.3 T protein histidine kinase activity
CFDECGKC_01657 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
CFDECGKC_01658 1.8e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CFDECGKC_01659 0.0 amiA E ABC transporter, substrate-binding protein, family 5
CFDECGKC_01660 2.4e-119 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CFDECGKC_01661 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CFDECGKC_01662 4.6e-50 S Protein of unknown function (DUF3397)
CFDECGKC_01663 9.2e-89 cah 4.2.1.1 P Reversible hydration of carbon dioxide
CFDECGKC_01664 7e-127 WQ51_05710 S Mitochondrial biogenesis AIM24
CFDECGKC_01665 3.1e-226 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CFDECGKC_01666 1.9e-76 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
CFDECGKC_01667 2.7e-79 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
CFDECGKC_01668 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
CFDECGKC_01669 9.3e-231 XK27_09615 C reductase
CFDECGKC_01670 1.6e-140 fnt P Formate nitrite transporter
CFDECGKC_01671 7.9e-97 XK27_08585 S Psort location CytoplasmicMembrane, score
CFDECGKC_01672 5.7e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CFDECGKC_01673 1e-170 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CFDECGKC_01674 4.4e-118 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CFDECGKC_01675 2.2e-96 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CFDECGKC_01676 4.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CFDECGKC_01677 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CFDECGKC_01678 9.2e-141 S HAD hydrolase, family IA, variant
CFDECGKC_01679 2.2e-159 rrmA 2.1.1.187 Q methyltransferase
CFDECGKC_01683 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CFDECGKC_01684 2.5e-65 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CFDECGKC_01685 8.3e-37 yeeD O sulfur carrier activity
CFDECGKC_01686 2e-186 yeeE S Sulphur transport
CFDECGKC_01687 5.7e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CFDECGKC_01689 3.6e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CFDECGKC_01690 3.5e-08 XK27_10305 S Domain of unknown function (DUF4651)
CFDECGKC_01691 5.7e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CFDECGKC_01692 9.6e-102 S CAAX amino terminal protease family protein
CFDECGKC_01694 1.4e-108 V CAAX protease self-immunity
CFDECGKC_01695 8.8e-27 lanR K sequence-specific DNA binding
CFDECGKC_01696 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CFDECGKC_01697 3.6e-174 ytxK 2.1.1.72 L DNA methylase
CFDECGKC_01698 2e-12 comGF U Putative Competence protein ComGF
CFDECGKC_01699 4.5e-71 comGF U Competence protein ComGF
CFDECGKC_01700 3.1e-15 NU Type II secretory pathway pseudopilin
CFDECGKC_01701 1.4e-69 cglD NU Competence protein
CFDECGKC_01702 2.2e-43 comGC U Required for transformation and DNA binding
CFDECGKC_01703 1.3e-143 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFDECGKC_01704 1.1e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CFDECGKC_01705 3.8e-68 S cog cog4699
CFDECGKC_01706 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDECGKC_01707 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CFDECGKC_01708 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CFDECGKC_01709 1.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CFDECGKC_01710 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CFDECGKC_01711 2.2e-76 ilvN 2.2.1.6 E Acetolactate synthase
CFDECGKC_01712 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
CFDECGKC_01713 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CFDECGKC_01714 1.2e-302 yloV S kinase related to dihydroxyacetone kinase
CFDECGKC_01715 1.4e-57 asp S cog cog1302
CFDECGKC_01716 1.6e-225 norN V Mate efflux family protein
CFDECGKC_01717 7.8e-277 thrC 4.2.3.1 E Threonine synthase
CFDECGKC_01720 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
CFDECGKC_01721 0.0 pepO 3.4.24.71 O Peptidase family M13
CFDECGKC_01722 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CFDECGKC_01723 1.7e-287 treB 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
CFDECGKC_01724 7.9e-126 treR K trehalose operon
CFDECGKC_01725 1.9e-95 ywlG S Belongs to the UPF0340 family
CFDECGKC_01728 1.5e-93
CFDECGKC_01729 7.3e-12 K DNA-templated transcription, initiation
CFDECGKC_01730 7.1e-76 3.4.21.89 S RDD family
CFDECGKC_01731 1.2e-14
CFDECGKC_01733 2.2e-84 Q Methyltransferase domain
CFDECGKC_01734 2.7e-146 S TraX protein
CFDECGKC_01735 2.3e-119 KT Transcriptional regulatory protein, C terminal
CFDECGKC_01736 1.2e-231 T PhoQ Sensor
CFDECGKC_01737 8.1e-257 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CFDECGKC_01738 1.1e-141 XK27_05470 E Methionine synthase
CFDECGKC_01739 2.8e-38 XK27_05470 E Methionine synthase
CFDECGKC_01740 1.6e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CFDECGKC_01741 5.3e-44 pspE P Rhodanese-like protein
CFDECGKC_01742 2.4e-136 IQ Acetoin reductase
CFDECGKC_01744 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CFDECGKC_01745 2.3e-53 S Bacterial protein of unknown function (DUF961)
CFDECGKC_01746 1e-63 S Bacterial protein of unknown function (DUF961)
CFDECGKC_01747 3.7e-265 D Domain of unknown function DUF87
CFDECGKC_01748 1.6e-232 K Replication initiation factor
CFDECGKC_01749 1.9e-30 S Psort location CytoplasmicMembrane, score
CFDECGKC_01750 7.5e-91 S Antirestriction protein (ArdA)
CFDECGKC_01751 3.8e-90 S TcpE family
CFDECGKC_01752 0.0 S AAA-like domain
CFDECGKC_01753 0.0 S the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_01754 2.2e-190 yddH M NlpC p60 family protein
CFDECGKC_01755 7.4e-169 S Conjugative transposon protein TcpC
CFDECGKC_01756 3.2e-145 yjjH S Calcineurin-like phosphoesterase
CFDECGKC_01757 4.2e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CFDECGKC_01758 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CFDECGKC_01759 3.2e-124 ftsE D cell division ATP-binding protein FtsE
CFDECGKC_01760 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CFDECGKC_01761 6.6e-92 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
CFDECGKC_01762 1.2e-176 yubA S permease
CFDECGKC_01763 3.1e-223 G COG0457 FOG TPR repeat
CFDECGKC_01764 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CFDECGKC_01765 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CFDECGKC_01766 1.2e-227 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CFDECGKC_01767 1.5e-86 ebsA S Family of unknown function (DUF5322)
CFDECGKC_01768 5.5e-17 M LysM domain
CFDECGKC_01769 2.8e-120 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CFDECGKC_01770 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CFDECGKC_01771 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CFDECGKC_01772 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CFDECGKC_01773 4.2e-83 XK27_03610 K Gnat family
CFDECGKC_01774 3.2e-92 yybC
CFDECGKC_01775 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
CFDECGKC_01776 1.7e-273 pepV 3.5.1.18 E Dipeptidase
CFDECGKC_01777 1.4e-107 ung2 3.2.2.27 L Uracil-DNA glycosylase
CFDECGKC_01778 1.3e-07 V Glucan-binding protein C
CFDECGKC_01779 6.7e-48 U AAA-like domain
CFDECGKC_01781 2.1e-14
CFDECGKC_01783 4.1e-42 xisC L viral genome integration into host DNA
CFDECGKC_01785 4.1e-120 K helix_turn_helix, arabinose operon control protein
CFDECGKC_01786 6.7e-106 I Psort location Cytoplasmic, score
CFDECGKC_01787 4.1e-189 G Protein of unknown function (DUF4038)
CFDECGKC_01788 6.4e-177 G pts system
CFDECGKC_01789 0.0 G Part of a membrane complex involved in electron transport
CFDECGKC_01790 2.4e-51 L Transposase
CFDECGKC_01791 3.9e-102 tcyB_2 P ABC transporter (permease)
CFDECGKC_01792 3.2e-153 endA F DNA RNA non-specific endonuclease
CFDECGKC_01793 5.5e-26 epuA S DNA-directed RNA polymerase subunit beta
CFDECGKC_01794 7.7e-233 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CFDECGKC_01795 3.7e-11 S Protein of unknown function (DUF1146)
CFDECGKC_01796 3.3e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CFDECGKC_01797 3.2e-134 G Domain of unknown function (DUF4832)
CFDECGKC_01798 9.2e-84 S membrane
CFDECGKC_01799 6.7e-96 P VTC domain
CFDECGKC_01800 1e-222 cotH M CotH kinase protein
CFDECGKC_01801 4.9e-183 pelG M Putative exopolysaccharide Exporter (EPS-E)
CFDECGKC_01802 1.4e-270 pelF GT4 M Domain of unknown function (DUF3492)
CFDECGKC_01803 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
CFDECGKC_01804 1.5e-145
CFDECGKC_01805 4.6e-276 5.1.3.2 GM Psort location CytoplasmicMembrane, score
CFDECGKC_01806 1e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CFDECGKC_01807 3.3e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CFDECGKC_01808 6.4e-304 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CFDECGKC_01809 3.6e-88 ytsP 1.8.4.14 T GAF domain-containing protein
CFDECGKC_01810 4.3e-161 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CFDECGKC_01811 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
CFDECGKC_01814 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CFDECGKC_01815 7.8e-214 XK27_05110 P Chloride transporter ClC family
CFDECGKC_01816 6.9e-38 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
CFDECGKC_01817 2.4e-281 clcA P Chloride transporter, ClC family
CFDECGKC_01818 1e-75 fld C Flavodoxin
CFDECGKC_01819 2.2e-18 XK27_08880
CFDECGKC_01820 1.4e-125 XK27_08875 O Zinc-dependent metalloprotease
CFDECGKC_01821 5e-150 estA CE1 S Esterase
CFDECGKC_01822 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDECGKC_01823 1.5e-135 XK27_08845 S abc transporter atp-binding protein
CFDECGKC_01824 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
CFDECGKC_01825 1.8e-176 XK27_08835 S ABC transporter substrate binding protein
CFDECGKC_01826 8.4e-18 S Domain of unknown function (DUF4649)
CFDECGKC_01827 1.2e-138 Q the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_01828 1.2e-241 htaA 3.4.21.72 Q the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_01829 2.5e-25 Q the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_01830 2.7e-277 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CFDECGKC_01831 1e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CFDECGKC_01832 0.0 dnaE 2.7.7.7 L DNA polymerase
CFDECGKC_01833 1.1e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDECGKC_01834 1.2e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CFDECGKC_01835 2.1e-37 ysdA L Membrane
CFDECGKC_01836 6.6e-190 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CFDECGKC_01837 6.4e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CFDECGKC_01838 2.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CFDECGKC_01839 1.1e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
CFDECGKC_01841 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CFDECGKC_01842 5.2e-96 ypmS S Protein conserved in bacteria
CFDECGKC_01843 3.4e-155 ypmR E COG2755 Lysophospholipase L1 and related esterases
CFDECGKC_01844 2.5e-147 DegV S DegV family
CFDECGKC_01845 4.6e-302 recN L May be involved in recombinational repair of damaged DNA
CFDECGKC_01846 1.6e-71 argR K Regulates arginine biosynthesis genes
CFDECGKC_01847 5.5e-147 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
CFDECGKC_01848 1.7e-154 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CFDECGKC_01849 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDECGKC_01850 1.6e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CFDECGKC_01852 4.9e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CFDECGKC_01853 2.5e-124 dnaD
CFDECGKC_01854 5.1e-181 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CFDECGKC_01855 9.9e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CFDECGKC_01856 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
CFDECGKC_01857 1.2e-65 GnaT 2.5.1.16 K acetyltransferase
CFDECGKC_01858 1.6e-126 Q Methyltransferase domain
CFDECGKC_01859 2.8e-137 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CFDECGKC_01860 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CFDECGKC_01861 7.6e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
CFDECGKC_01862 3.2e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CFDECGKC_01863 8.4e-236 rodA D Belongs to the SEDS family
CFDECGKC_01864 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_01865 1.3e-163 L High confidence in function and specificity
CFDECGKC_01866 2e-42 mccF V LD-carboxypeptidase
CFDECGKC_01867 1.5e-14 L COG3547 Transposase and inactivated derivatives
CFDECGKC_01868 4.1e-57 L transposase IS116 IS110 IS902 family
CFDECGKC_01869 1e-103 L COG3547 Transposase and inactivated derivatives
CFDECGKC_01870 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_01871 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_01872 3e-179 XK27_08075 M glycosyl transferase family 2
CFDECGKC_01873 6.6e-99 S Carbohydrate-binding domain-containing protein Cthe_2159
CFDECGKC_01874 1.3e-142 P molecular chaperone
CFDECGKC_01875 1.3e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
CFDECGKC_01878 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
CFDECGKC_01879 1.4e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CFDECGKC_01880 1.8e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CFDECGKC_01881 1e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CFDECGKC_01882 1.5e-109 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CFDECGKC_01883 5.7e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CFDECGKC_01884 3.2e-234 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CFDECGKC_01885 5.5e-118 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CFDECGKC_01886 2.9e-179 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CFDECGKC_01887 4.3e-189 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CFDECGKC_01888 8.6e-58 XK27_08085
CFDECGKC_01889 5.2e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
CFDECGKC_01890 3.3e-135 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
CFDECGKC_01891 5.9e-112 ylfI S tigr01906
CFDECGKC_01892 1.4e-136 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CFDECGKC_01893 6.9e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
CFDECGKC_01894 3.8e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
CFDECGKC_01895 4.9e-30 KT response to antibiotic
CFDECGKC_01897 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CFDECGKC_01898 6.4e-113 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
CFDECGKC_01899 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CFDECGKC_01900 1.5e-255 S phospholipase Carboxylesterase
CFDECGKC_01901 3.7e-199 yurR 1.4.5.1 E oxidoreductase
CFDECGKC_01902 4.4e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
CFDECGKC_01903 6.4e-145 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CFDECGKC_01904 2.6e-118 trmK 2.1.1.217 S SAM-dependent methyltransferase
CFDECGKC_01905 1.3e-64 gtrA S GtrA-like protein
CFDECGKC_01906 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CFDECGKC_01907 8.4e-163 ybbR S Protein conserved in bacteria
CFDECGKC_01908 1.8e-148 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CFDECGKC_01909 1.2e-255 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
CFDECGKC_01910 2.3e-150 cobQ S glutamine amidotransferase
CFDECGKC_01911 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFDECGKC_01912 2e-132 pip 1.11.1.10 S Alpha beta hydrolase
CFDECGKC_01913 1.6e-39 MA20_06245 S yiaA/B two helix domain
CFDECGKC_01914 0.0 uup S abc transporter atp-binding protein
CFDECGKC_01915 5.2e-113 udk 2.7.1.48 F Cytidine monophosphokinase
CFDECGKC_01916 1.2e-178 yfmL 3.6.4.13 L DEAD DEAH box helicase
CFDECGKC_01917 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
CFDECGKC_01918 2.7e-153 XK27_05675 S Esterase
CFDECGKC_01919 6.1e-162 XK27_05670 S Putative esterase
CFDECGKC_01920 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
CFDECGKC_01921 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CFDECGKC_01922 3e-38 ptsH G phosphocarrier protein Hpr
CFDECGKC_01923 1.5e-222 icd 1.1.1.42 C Isocitrate dehydrogenase
CFDECGKC_01924 1.3e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
CFDECGKC_01925 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CFDECGKC_01926 2.2e-34 nrdH O Glutaredoxin
CFDECGKC_01927 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDECGKC_01928 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CFDECGKC_01929 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
CFDECGKC_01930 1e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CFDECGKC_01931 1.8e-229 cinA 3.5.1.42 S Belongs to the CinA family
CFDECGKC_01932 1.2e-105 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
CFDECGKC_01933 1e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CFDECGKC_01935 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CFDECGKC_01937 5.4e-69 K LytTr DNA-binding domain
CFDECGKC_01938 1e-78 S Protein of unknown function (DUF3021)
CFDECGKC_01939 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CFDECGKC_01940 1.1e-56 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CFDECGKC_01941 3.1e-69 argR K Regulates arginine biosynthesis genes
CFDECGKC_01942 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
CFDECGKC_01943 2.5e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CFDECGKC_01944 1.4e-70 S KAP family P-loop domain
CFDECGKC_01945 1.9e-15 S NYN domain
CFDECGKC_01946 1.1e-200 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CFDECGKC_01947 2.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CFDECGKC_01948 2.3e-237 purD 6.3.4.13 F Belongs to the GARS family
CFDECGKC_01949 2.3e-156 S CHAP domain
CFDECGKC_01950 3.6e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CFDECGKC_01951 9.9e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CFDECGKC_01952 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CFDECGKC_01953 6.4e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CFDECGKC_01954 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CFDECGKC_01955 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CFDECGKC_01956 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CFDECGKC_01957 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CFDECGKC_01958 8e-140 recO L Involved in DNA repair and RecF pathway recombination
CFDECGKC_01959 2.5e-217 araT 2.6.1.1 E Aminotransferase
CFDECGKC_01960 1.2e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CFDECGKC_01961 2.1e-83 usp 3.5.1.28 CBM50 S CHAP domain
CFDECGKC_01962 1.1e-81 mreD M rod shape-determining protein MreD
CFDECGKC_01963 3.2e-94 mreC M Involved in formation and maintenance of cell shape
CFDECGKC_01967 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CFDECGKC_01968 1.5e-33 ykzG S Belongs to the UPF0356 family
CFDECGKC_01969 1.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
CFDECGKC_01970 6.9e-72 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CFDECGKC_01971 2.8e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CFDECGKC_01972 3.7e-112 azlC E AzlC protein
CFDECGKC_01973 1.3e-46 azlD S branched-chain amino acid
CFDECGKC_01974 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CFDECGKC_01975 1.5e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
CFDECGKC_01976 2.5e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CFDECGKC_01977 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CFDECGKC_01978 6.1e-94 cvpA S toxin biosynthetic process
CFDECGKC_01979 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CFDECGKC_01980 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CFDECGKC_01982 4.9e-34
CFDECGKC_01983 2.1e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
CFDECGKC_01984 6.4e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CFDECGKC_01985 3.2e-220 vicK 2.7.13.3 T Histidine kinase
CFDECGKC_01986 4.6e-154 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
CFDECGKC_01987 6.7e-57 S Protein of unknown function (DUF454)
CFDECGKC_01988 1.9e-225 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
CFDECGKC_01989 1.3e-145 yidA S hydrolases of the HAD superfamily
CFDECGKC_01990 1.3e-146 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
CFDECGKC_01991 2.6e-67 ywiB S Domain of unknown function (DUF1934)
CFDECGKC_01992 0.0 pacL 3.6.3.8 P cation transport ATPase
CFDECGKC_01993 3.5e-132 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
CFDECGKC_01994 1.7e-154 L the current gene model (or a revised gene model) may contain a frame shift
CFDECGKC_01996 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CFDECGKC_01997 1.4e-162 mleP S auxin efflux carrier
CFDECGKC_01998 8.4e-309 sfcA 1.1.1.38, 4.1.1.101 C malic enzyme
CFDECGKC_01999 1.9e-48 K Helix-turn-helix
CFDECGKC_02000 1.5e-118 mleR K malolactic fermentation system
CFDECGKC_02001 2.6e-127 XK27_00785 S CAAX protease self-immunity
CFDECGKC_02002 6.4e-233 EGP Major facilitator Superfamily
CFDECGKC_02003 3.7e-52 rmaI K Transcriptional regulator, MarR family
CFDECGKC_02004 1.8e-93 maa 2.3.1.79 GK Maltose O-acetyltransferase
CFDECGKC_02005 1.2e-64 2.7.13.3 T Histidine kinase
CFDECGKC_02006 2.3e-74 K Transcriptional regulatory protein, C terminal
CFDECGKC_02008 2.4e-14
CFDECGKC_02009 2.9e-88 V abc transporter atp-binding protein
CFDECGKC_02010 4.2e-223 L Transposase
CFDECGKC_02011 0.0 3.5.1.28 M domain protein
CFDECGKC_02012 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
CFDECGKC_02013 7.1e-24
CFDECGKC_02014 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
CFDECGKC_02015 1.2e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CFDECGKC_02016 9.7e-82 queD 4.1.2.50, 4.2.3.12 H synthase
CFDECGKC_02017 7.9e-134 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CFDECGKC_02018 2.5e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)