ORF_ID e_value Gene_name EC_number CAZy COGs Description
OOOKNECK_00005 7.8e-08
OOOKNECK_00013 1.6e-08
OOOKNECK_00017 5.9e-275 C Na+/H+ antiporter family
OOOKNECK_00018 3.3e-60 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OOOKNECK_00019 3.1e-44 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
OOOKNECK_00020 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OOOKNECK_00021 1.3e-246 ygaK C Berberine and berberine like
OOOKNECK_00023 6.4e-230 oppA5 E PFAM extracellular solute-binding protein family 5
OOOKNECK_00024 3.5e-145 appB P Binding-protein-dependent transport system inner membrane component
OOOKNECK_00025 4.1e-127 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00026 9.8e-135 oppD3 P Belongs to the ABC transporter superfamily
OOOKNECK_00027 2.9e-131 oppF3 E Belongs to the ABC transporter superfamily
OOOKNECK_00028 2e-285 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OOOKNECK_00029 4.7e-179 S Amidohydrolase
OOOKNECK_00030 4.3e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
OOOKNECK_00031 5e-171 ssuA M Sulfonate ABC transporter
OOOKNECK_00032 2.4e-142 ssuC P ABC transporter (permease)
OOOKNECK_00033 1.8e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
OOOKNECK_00035 3.9e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OOOKNECK_00036 8.9e-78 ygaO
OOOKNECK_00037 1.8e-22 K Transcriptional regulator
OOOKNECK_00039 4.2e-107 yhzB S B3/4 domain
OOOKNECK_00040 6.2e-221 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OOOKNECK_00041 2.9e-168 yhbB S Putative amidase domain
OOOKNECK_00042 2.2e-84 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
OOOKNECK_00043 3.2e-102 yhbD K Protein of unknown function (DUF4004)
OOOKNECK_00044 3.8e-12 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OOOKNECK_00045 5.6e-37 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
OOOKNECK_00046 1.3e-56 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
OOOKNECK_00048 0.0 prkA T Ser protein kinase
OOOKNECK_00049 1.7e-213 yhbH S Belongs to the UPF0229 family
OOOKNECK_00050 1.6e-71 yhbI K DNA-binding transcription factor activity
OOOKNECK_00052 1.7e-82 yhbJ V COG1566 Multidrug resistance efflux pump
OOOKNECK_00053 4.1e-284 yhcA EGP Major facilitator Superfamily
OOOKNECK_00054 1e-98 yhcB 1.6.5.2 S NADPH-dependent FMN reductase
OOOKNECK_00055 5.3e-49 yhcC
OOOKNECK_00056 3.6e-52
OOOKNECK_00057 3.7e-58 yhcF K Transcriptional regulator
OOOKNECK_00058 7.4e-116 yhcG V ABC transporter, ATP-binding protein
OOOKNECK_00059 7.2e-164 yhcH V ABC transporter, ATP-binding protein
OOOKNECK_00060 7.9e-158 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OOOKNECK_00061 3.9e-30 cspB K 'Cold-shock' DNA-binding domain
OOOKNECK_00062 1.2e-128 metQ M Belongs to the nlpA lipoprotein family
OOOKNECK_00063 4e-182 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
OOOKNECK_00064 8.6e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOOKNECK_00065 6.9e-40 amaB 3.5.1.6, 3.5.1.87 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OOOKNECK_00066 4.4e-38 yhcM
OOOKNECK_00067 6.3e-74 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOOKNECK_00068 1.3e-154 yhcP
OOOKNECK_00069 9.4e-113 yhcQ M Spore coat protein
OOOKNECK_00070 3.8e-298 yhcR 3.1.3.5 F Belongs to the 5'-nucleotidase family
OOOKNECK_00071 6.9e-99 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
OOOKNECK_00072 3.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOOKNECK_00073 1.7e-61 yhcU S Family of unknown function (DUF5365)
OOOKNECK_00074 8.4e-67 yhcV S COG0517 FOG CBS domain
OOOKNECK_00075 1e-122 yhcW 5.4.2.6 S hydrolase
OOOKNECK_00076 1.9e-302 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OOOKNECK_00077 2.2e-254 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOOKNECK_00078 3.2e-101 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
OOOKNECK_00079 1.5e-141 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
OOOKNECK_00080 8.9e-289 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OOOKNECK_00081 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OOOKNECK_00082 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
OOOKNECK_00083 1.6e-192 yhcY 2.7.13.3 T Histidine kinase
OOOKNECK_00084 2.5e-107 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_00085 5e-85 azr 1.7.1.6 S NADPH-dependent FMN reductase
OOOKNECK_00086 8e-38 yhdB S YhdB-like protein
OOOKNECK_00087 1.3e-51 yhdC S Protein of unknown function (DUF3889)
OOOKNECK_00088 2e-200 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OOOKNECK_00089 5.8e-71 nsrR K Transcriptional regulator
OOOKNECK_00090 3.5e-248 ygxB M Conserved TM helix
OOOKNECK_00091 4.6e-20 ycgB S Stage V sporulation protein R
OOOKNECK_00092 6.3e-224 ycgB S Stage V sporulation protein R
OOOKNECK_00093 6.2e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
OOOKNECK_00094 3.3e-123 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OOOKNECK_00095 2.8e-157 citR K Transcriptional regulator
OOOKNECK_00096 4.6e-197 citA 2.3.3.1 C Belongs to the citrate synthase family
OOOKNECK_00097 2.3e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_00098 6.1e-247 yhdG E amino acid
OOOKNECK_00099 1.6e-196 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OOOKNECK_00100 8.1e-45 yhdK S Sigma-M inhibitor protein
OOOKNECK_00101 3.2e-195 yhdL S Sigma factor regulator N-terminal
OOOKNECK_00102 4.2e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_00103 5.8e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OOOKNECK_00104 4e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OOOKNECK_00105 1.8e-69 cueR K transcriptional
OOOKNECK_00106 1.5e-217 yhdR 2.6.1.1 E Aminotransferase
OOOKNECK_00107 3.3e-228 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOOKNECK_00108 5.3e-22 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OOOKNECK_00109 2.4e-201 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
OOOKNECK_00110 8.8e-49 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OOOKNECK_00111 3.4e-54 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OOOKNECK_00112 1.2e-121 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOOKNECK_00114 2.7e-197 yhdY M Mechanosensitive ion channel
OOOKNECK_00115 1.7e-134 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
OOOKNECK_00116 5.5e-150 yheN G deacetylase
OOOKNECK_00117 2.7e-149 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
OOOKNECK_00118 1.1e-81 pksA K Transcriptional regulator
OOOKNECK_00119 7e-90 ymcC S Membrane
OOOKNECK_00120 1.5e-83 T universal stress protein
OOOKNECK_00121 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOOKNECK_00122 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOOKNECK_00123 1.9e-99 yheG GM NAD(P)H-binding
OOOKNECK_00125 3.8e-28 sspB S spore protein
OOOKNECK_00126 1.7e-36 yheE S Family of unknown function (DUF5342)
OOOKNECK_00127 1.1e-248 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
OOOKNECK_00128 6.1e-202 yheC HJ YheC/D like ATP-grasp
OOOKNECK_00129 8.5e-199 yheB S Belongs to the UPF0754 family
OOOKNECK_00130 2.8e-52 yheA S Belongs to the UPF0342 family
OOOKNECK_00131 2.7e-152 yhaX S haloacid dehalogenase-like hydrolase
OOOKNECK_00132 1.1e-291 hemZ H coproporphyrinogen III oxidase
OOOKNECK_00133 1.5e-244 iucD 1.14.13.59 Q L-lysine 6-monooxygenase (NADPH-requiring)
OOOKNECK_00134 5.5e-204 yhaU P COG0475 Kef-type K transport systems, membrane components
OOOKNECK_00135 8.6e-87 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
OOOKNECK_00137 1.2e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
OOOKNECK_00138 1.2e-14 S YhzD-like protein
OOOKNECK_00139 5.9e-163 yhaQ S ABC transporter, ATP-binding protein
OOOKNECK_00140 1.7e-203 yhaP CP COG1668 ABC-type Na efflux pump, permease component
OOOKNECK_00141 9.1e-231 yhaO L DNA repair exonuclease
OOOKNECK_00142 0.0 yhaN L AAA domain
OOOKNECK_00143 1.1e-175 yhaM L Shows a 3'-5' exoribonuclease activity
OOOKNECK_00144 2.3e-31 yhaL S Sporulation protein YhaL
OOOKNECK_00145 1.1e-113 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
OOOKNECK_00146 1e-93 yhaK S Putative zincin peptidase
OOOKNECK_00147 9.9e-55 yhaI S Protein of unknown function (DUF1878)
OOOKNECK_00148 1.5e-109 hpr K Negative regulator of protease production and sporulation
OOOKNECK_00149 9e-38 yhaH S YtxH-like protein
OOOKNECK_00150 2e-17
OOOKNECK_00151 1.3e-74 trpP S Tryptophan transporter TrpP
OOOKNECK_00152 1.5e-197 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OOOKNECK_00153 2.4e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
OOOKNECK_00154 4.4e-135 ecsA V transporter (ATP-binding protein)
OOOKNECK_00155 5.7e-217 ecsB U ABC transporter
OOOKNECK_00156 1.1e-116 ecsC S EcsC protein family
OOOKNECK_00157 1.4e-215 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
OOOKNECK_00158 2.5e-237 yhfA C membrane
OOOKNECK_00159 6e-88 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
OOOKNECK_00160 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOOKNECK_00161 6.9e-23 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OOOKNECK_00162 4.5e-163 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OOOKNECK_00163 1.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
OOOKNECK_00164 6.6e-273 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
OOOKNECK_00165 3.5e-100 yhgD K Transcriptional regulator
OOOKNECK_00166 1.6e-255 yhgE S YhgE Pip N-terminal domain protein
OOOKNECK_00167 1.3e-176 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OOOKNECK_00169 1.5e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
OOOKNECK_00170 1.2e-225 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOOKNECK_00171 6.2e-134 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
OOOKNECK_00172 1.7e-187 lplJ 6.3.1.20 H Lipoate-protein ligase
OOOKNECK_00173 5.7e-107 yhfK GM NmrA-like family
OOOKNECK_00174 1.7e-295 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OOOKNECK_00175 8.1e-64 yhfM
OOOKNECK_00176 5.4e-231 yhfN 3.4.24.84 O Peptidase M48
OOOKNECK_00177 1.6e-200 aprE 3.4.21.62 O Belongs to the peptidase S8 family
OOOKNECK_00178 7e-129 yhfQ P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
OOOKNECK_00179 1.2e-100 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
OOOKNECK_00180 1.4e-193 vraB 2.3.1.9 I Belongs to the thiolase family
OOOKNECK_00181 6.2e-263 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
OOOKNECK_00182 3.1e-85 bioY S BioY family
OOOKNECK_00183 2.4e-197 hemAT NT chemotaxis protein
OOOKNECK_00184 1e-262 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
OOOKNECK_00185 1.4e-158 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_00186 1.2e-30 yhzC S IDEAL
OOOKNECK_00187 4.2e-109 comK K Competence transcription factor
OOOKNECK_00188 4.1e-57 frataxin S Domain of unknown function (DU1801)
OOOKNECK_00189 6.1e-171 els S Acetyltransferase, GNAT family
OOOKNECK_00190 1.2e-121 yrpD S Domain of unknown function, YrpD
OOOKNECK_00191 7.8e-42 yhjA S Excalibur calcium-binding domain
OOOKNECK_00192 3.3e-47 S Belongs to the UPF0145 family
OOOKNECK_00193 1.2e-261 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOOKNECK_00194 3.1e-27 yhjC S Protein of unknown function (DUF3311)
OOOKNECK_00195 7.9e-58 yhjD
OOOKNECK_00196 1e-105 yhjE S SNARE associated Golgi protein
OOOKNECK_00197 6.6e-90 sipV 3.4.21.89 U Belongs to the peptidase S26 family
OOOKNECK_00198 3.4e-264 yhjG CH FAD binding domain
OOOKNECK_00199 6.1e-91 yhjH K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_00200 7.9e-184 abrB S membrane
OOOKNECK_00201 2.6e-198 blt EGP Major facilitator Superfamily
OOOKNECK_00202 3.5e-106 K QacR-like protein, C-terminal region
OOOKNECK_00203 1.4e-82 yhjR S Rubrerythrin
OOOKNECK_00204 1.2e-118 ydfS S Protein of unknown function (DUF421)
OOOKNECK_00205 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
OOOKNECK_00206 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
OOOKNECK_00207 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
OOOKNECK_00208 0.0 sbcC L COG0419 ATPase involved in DNA repair
OOOKNECK_00209 3.9e-50 yisB V COG1403 Restriction endonuclease
OOOKNECK_00210 1.7e-31 gerPF S Spore germination protein gerPA/gerPF
OOOKNECK_00211 2.1e-59 gerPE S Spore germination protein GerPE
OOOKNECK_00212 7.7e-22 gerPD S Spore germination protein
OOOKNECK_00213 5.9e-61 gerPC S Spore germination protein
OOOKNECK_00214 4.8e-32 gerPB S cell differentiation
OOOKNECK_00215 8.4e-34 gerPA S Spore germination protein
OOOKNECK_00216 1.6e-08 yisI S Spo0E like sporulation regulatory protein
OOOKNECK_00217 2e-166 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
OOOKNECK_00218 1.9e-59 yisL S UPF0344 protein
OOOKNECK_00219 0.0 wprA O Belongs to the peptidase S8 family
OOOKNECK_00220 3.1e-90 yisN S Protein of unknown function (DUF2777)
OOOKNECK_00221 0.0 asnO 6.3.5.4 E Asparagine synthase
OOOKNECK_00222 7e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
OOOKNECK_00223 1e-241 yisQ V Mate efflux family protein
OOOKNECK_00224 8e-157 yisR K Transcriptional regulator
OOOKNECK_00225 8.6e-142 purR K helix_turn _helix lactose operon repressor
OOOKNECK_00226 4.4e-154 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
OOOKNECK_00227 5.2e-77 yisT S DinB family
OOOKNECK_00228 1e-73 argO S Lysine exporter protein LysE YggA
OOOKNECK_00229 1e-188 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_00230 2.4e-49 mcbG S Pentapeptide repeats (9 copies)
OOOKNECK_00231 6e-76 yjcF S Acetyltransferase (GNAT) domain
OOOKNECK_00232 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
OOOKNECK_00233 5e-31 yajQ S Belongs to the UPF0234 family
OOOKNECK_00234 1.1e-07 yajQ S Belongs to the UPF0234 family
OOOKNECK_00235 7.4e-20 cvfB S protein conserved in bacteria
OOOKNECK_00236 2.1e-120 cvfB S protein conserved in bacteria
OOOKNECK_00237 5e-147 yufN S ABC transporter substrate-binding protein PnrA-like
OOOKNECK_00238 1.9e-175 yvaQ NT Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer).
OOOKNECK_00239 1.3e-232 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
OOOKNECK_00241 1.3e-154 yitS S protein conserved in bacteria
OOOKNECK_00242 8.7e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_00243 1.2e-79 ipi S Intracellular proteinase inhibitor
OOOKNECK_00244 9.8e-26 S Protein of unknown function (DUF3813)
OOOKNECK_00245 2e-07
OOOKNECK_00246 4.4e-149 yitU 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OOOKNECK_00247 3.2e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
OOOKNECK_00248 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
OOOKNECK_00249 3.6e-70 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
OOOKNECK_00250 5.1e-265 yitY C D-arabinono-1,4-lactone oxidase
OOOKNECK_00251 9.4e-87 norB G Major Facilitator Superfamily
OOOKNECK_00252 1.4e-192 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OOOKNECK_00253 3.2e-220 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
OOOKNECK_00254 9.8e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
OOOKNECK_00255 2.2e-210 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
OOOKNECK_00256 1.4e-195 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OOOKNECK_00257 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
OOOKNECK_00258 3.4e-172 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OOOKNECK_00259 2.1e-27 yjzC S YjzC-like protein
OOOKNECK_00260 6.3e-22 yjzD S Protein of unknown function (DUF2929)
OOOKNECK_00261 2.9e-131 yjaU I carboxylic ester hydrolase activity
OOOKNECK_00262 5.5e-98 yjaV
OOOKNECK_00263 2e-163 med S Transcriptional activator protein med
OOOKNECK_00264 3.3e-26 comZ S ComZ
OOOKNECK_00266 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OOOKNECK_00267 1.2e-230 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOOKNECK_00268 3.6e-140 yjaZ O Zn-dependent protease
OOOKNECK_00269 1.6e-180 appD P Belongs to the ABC transporter superfamily
OOOKNECK_00270 5.7e-183 appF E Belongs to the ABC transporter superfamily
OOOKNECK_00271 0.0 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
OOOKNECK_00272 4.8e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00273 1.8e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00274 5.5e-146 yjbA S Belongs to the UPF0736 family
OOOKNECK_00275 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
OOOKNECK_00276 0.0 oppA E ABC transporter substrate-binding protein
OOOKNECK_00277 7.8e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00278 6.5e-165 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00279 1.2e-199 oppD P Belongs to the ABC transporter superfamily
OOOKNECK_00280 8.8e-170 oppF E Belongs to the ABC transporter superfamily
OOOKNECK_00281 9.2e-220 S Putative glycosyl hydrolase domain
OOOKNECK_00282 2.9e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOOKNECK_00283 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
OOOKNECK_00284 1.1e-108 yjbE P Integral membrane protein TerC family
OOOKNECK_00285 5e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OOOKNECK_00286 1.9e-201 yjbF S Competence protein
OOOKNECK_00287 0.0 pepF E oligoendopeptidase F
OOOKNECK_00288 5.8e-19
OOOKNECK_00289 2.6e-166 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OOOKNECK_00290 5.9e-70 yjbI S Bacterial-like globin
OOOKNECK_00291 7.9e-107 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OOOKNECK_00292 7.1e-93 yjbK S protein conserved in bacteria
OOOKNECK_00293 5e-60 yjbL S Belongs to the UPF0738 family
OOOKNECK_00294 1.9e-107 yjbM 2.7.6.5 S GTP pyrophosphokinase
OOOKNECK_00295 3.9e-150 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OOOKNECK_00296 4.1e-156 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOOKNECK_00297 5.5e-138 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
OOOKNECK_00298 2.7e-245 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
OOOKNECK_00299 8.7e-133 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
OOOKNECK_00300 4e-102 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
OOOKNECK_00301 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
OOOKNECK_00302 7.5e-29 thiS H Thiamine biosynthesis
OOOKNECK_00303 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
OOOKNECK_00304 3e-179 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OOOKNECK_00305 2.6e-141 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OOOKNECK_00306 6.8e-139 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
OOOKNECK_00307 5.4e-72 yjbX S Spore coat protein
OOOKNECK_00308 1.8e-80 cotZ S Spore coat protein
OOOKNECK_00309 1.3e-92 cotY S Spore coat protein Z
OOOKNECK_00310 1.3e-69 cotX S Spore Coat Protein X and V domain
OOOKNECK_00311 1.4e-21 cotW
OOOKNECK_00312 2.5e-33 cotV S Spore Coat Protein X and V domain
OOOKNECK_00313 2.8e-55 yjcA S Protein of unknown function (DUF1360)
OOOKNECK_00317 8.4e-38 spoVIF S Stage VI sporulation protein F
OOOKNECK_00318 0.0 yjcD 3.6.4.12 L DNA helicase
OOOKNECK_00319 6.2e-33
OOOKNECK_00320 2.4e-125 blm 3.5.2.6 S Belongs to the metallo-beta-lactamase superfamily. Class-B beta-lactamase family
OOOKNECK_00321 1.2e-104 S ABC-2 type transporter
OOOKNECK_00322 2.1e-129 nodI V AAA domain, putative AbiEii toxin, Type IV TA system
OOOKNECK_00323 8.8e-34 K SpoVT / AbrB like domain
OOOKNECK_00324 2e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOOKNECK_00325 7.8e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
OOOKNECK_00326 1.2e-121 yjcH P COG2382 Enterochelin esterase and related enzymes
OOOKNECK_00327 1.8e-209 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOOKNECK_00328 1.7e-213 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOOKNECK_00330 5.9e-55
OOOKNECK_00331 2.6e-74 yobL S Bacterial EndoU nuclease
OOOKNECK_00332 4.5e-31
OOOKNECK_00333 1.2e-72 yokH G SMI1 / KNR4 family
OOOKNECK_00334 5.5e-103 1.1.1.169 H 2-dehydropantoate 2-reductase
OOOKNECK_00335 4.3e-22 yokK S SMI1 / KNR4 family
OOOKNECK_00336 3e-62 H Acetyltransferase (GNAT) domain
OOOKNECK_00337 3.7e-25
OOOKNECK_00338 1.1e-197 K Psort location Cytoplasmic, score
OOOKNECK_00339 6.4e-311 K Psort location Cytoplasmic, score
OOOKNECK_00340 3.5e-36 S YolD-like protein
OOOKNECK_00341 5.8e-46 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOOKNECK_00342 6.5e-11 S Bacillus cereus group antimicrobial protein
OOOKNECK_00346 1.7e-28 N Kelch motif
OOOKNECK_00348 6.8e-154 bla 3.5.2.6 V beta-lactamase
OOOKNECK_00349 1.2e-45 yjcS S Antibiotic biosynthesis monooxygenase
OOOKNECK_00350 1.8e-238 yfjF EGP Belongs to the major facilitator superfamily
OOOKNECK_00351 2.2e-76 napB K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_00352 1.8e-217 ganA 3.2.1.89 G arabinogalactan
OOOKNECK_00353 3.7e-299 lacE 2.7.1.196, 2.7.1.205, 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOOKNECK_00354 3.4e-49 lacF 2.7.1.207 G phosphotransferase system
OOOKNECK_00355 1.6e-279 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
OOOKNECK_00356 1.4e-136 lacR K COG1349 Transcriptional regulators of sugar metabolism
OOOKNECK_00357 5.8e-118 5.4.2.6 S Haloacid dehalogenase-like hydrolase
OOOKNECK_00358 7.6e-34
OOOKNECK_00359 4.5e-52 K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_00360 2.2e-103 yhiD S MgtC SapB transporter
OOOKNECK_00362 5.4e-20 yjfB S Putative motility protein
OOOKNECK_00363 5.9e-62 T PhoQ Sensor
OOOKNECK_00364 2.9e-94 yjgB S Domain of unknown function (DUF4309)
OOOKNECK_00365 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OOOKNECK_00366 9.4e-87 yjgD S Protein of unknown function (DUF1641)
OOOKNECK_00367 2e-214 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
OOOKNECK_00368 1.8e-215 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OOOKNECK_00369 6.8e-29
OOOKNECK_00370 4.7e-141 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OOOKNECK_00371 3.8e-118 ybbM S transport system, permease component
OOOKNECK_00372 1.1e-125 pstB 3.6.3.27 P Belongs to the ABC transporter superfamily
OOOKNECK_00373 5.9e-172 yjlA EG Putative multidrug resistance efflux transporter
OOOKNECK_00374 7.3e-86 yjlB S Cupin domain
OOOKNECK_00375 7e-66 yjlC S Protein of unknown function (DUF1641)
OOOKNECK_00376 2.9e-163 yjlD 1.6.99.3 C NADH dehydrogenase
OOOKNECK_00377 3.7e-79 uxaC 5.3.1.12 G glucuronate isomerase
OOOKNECK_00378 5.4e-181 exuR K transcriptional
OOOKNECK_00379 6.3e-160 uxaA 4.2.1.7, 4.4.1.24 G Altronate
OOOKNECK_00380 5.2e-87 T Transcriptional regulatory protein, C terminal
OOOKNECK_00381 2.9e-129 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
OOOKNECK_00383 6.9e-128 MA20_18170 S membrane transporter protein
OOOKNECK_00384 4.9e-76 yjoA S DinB family
OOOKNECK_00385 3.2e-214 S response regulator aspartate phosphatase
OOOKNECK_00387 3.1e-162 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
OOOKNECK_00388 6.8e-60 yjqA S Bacterial PH domain
OOOKNECK_00389 4.8e-100 yjqB S phage-related replication protein
OOOKNECK_00390 1.5e-106 xkdA E IrrE N-terminal-like domain
OOOKNECK_00391 2.6e-55 xre K Helix-turn-helix XRE-family like proteins
OOOKNECK_00393 3.2e-144 xkdC L Bacterial dnaA protein
OOOKNECK_00396 4.5e-10 yqaO S Phage-like element PBSX protein XtrA
OOOKNECK_00397 8.5e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOOKNECK_00398 1.1e-107 xtmA L phage terminase small subunit
OOOKNECK_00399 1.6e-209 xtmB S phage terminase, large subunit
OOOKNECK_00400 2.5e-240 yqbA S portal protein
OOOKNECK_00401 7.5e-91 xkdF 2.1.1.72 L Putative phage serine protease XkdF
OOOKNECK_00402 3e-157 xkdG S Phage capsid family
OOOKNECK_00403 1.3e-45 yqbG S Protein of unknown function (DUF3199)
OOOKNECK_00404 3.3e-40 yqbH S Domain of unknown function (DUF3599)
OOOKNECK_00405 4.1e-60 xkdI S Bacteriophage HK97-gp10, putative tail-component
OOOKNECK_00406 5.8e-58 xkdJ
OOOKNECK_00407 6.3e-15
OOOKNECK_00408 3.2e-224 xkdK S Phage tail sheath C-terminal domain
OOOKNECK_00409 2e-74 xkdM S Phage tail tube protein
OOOKNECK_00410 1.7e-73 S Phage XkdN-like tail assembly chaperone protein, TAC
OOOKNECK_00411 3.4e-19
OOOKNECK_00412 1.6e-191 xkdO L Transglycosylase SLT domain
OOOKNECK_00413 1.3e-111 xkdP S Lysin motif
OOOKNECK_00414 2.9e-163 xkdQ 3.2.1.96 G NLP P60 protein
OOOKNECK_00415 8.5e-33 xkdR S Protein of unknown function (DUF2577)
OOOKNECK_00416 2.1e-57 xkdS S Protein of unknown function (DUF2634)
OOOKNECK_00417 7.4e-165 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
OOOKNECK_00418 7.2e-85 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
OOOKNECK_00419 6.1e-26
OOOKNECK_00420 8.6e-182
OOOKNECK_00421 1.3e-43 xkdW S XkdW protein
OOOKNECK_00422 3.4e-16 xkdX
OOOKNECK_00423 1.3e-105 xepA
OOOKNECK_00424 7.4e-37 xhlA S Haemolysin XhlA
OOOKNECK_00425 4.3e-37 xhlB S SPP1 phage holin
OOOKNECK_00426 7.6e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_00427 8.7e-23 spoIISB S Stage II sporulation protein SB
OOOKNECK_00428 1.7e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
OOOKNECK_00429 2.4e-173 pit P phosphate transporter
OOOKNECK_00430 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
OOOKNECK_00431 1.4e-240 steT E amino acid
OOOKNECK_00432 5.3e-178 mhqA E COG0346 Lactoylglutathione lyase and related lyases
OOOKNECK_00433 5.2e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OOOKNECK_00434 1.2e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOOKNECK_00436 5e-198 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOOKNECK_00437 2.3e-263 yubD P Major Facilitator Superfamily
OOOKNECK_00438 3.6e-154 dppA E D-aminopeptidase
OOOKNECK_00439 3.5e-158 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00440 5.3e-170 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
OOOKNECK_00441 3e-182 dppD P Belongs to the ABC transporter superfamily
OOOKNECK_00442 1.3e-309 dppE E ABC transporter substrate-binding protein
OOOKNECK_00443 1.9e-172 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
OOOKNECK_00444 1.1e-190 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
OOOKNECK_00445 2.4e-156 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OOOKNECK_00446 4.4e-180 ykfD E Belongs to the ABC transporter superfamily
OOOKNECK_00447 1.4e-200 pgl 3.1.1.31 G 6-phosphogluconolactonase
OOOKNECK_00448 1.5e-131 ykgA E Amidinotransferase
OOOKNECK_00449 8.4e-93 ykhA 3.1.2.20 I Acyl-CoA hydrolase
OOOKNECK_00450 4.4e-92 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OOOKNECK_00451 1.2e-48 ykkC P Multidrug resistance protein
OOOKNECK_00452 1e-48 ykkD P Multidrug resistance protein
OOOKNECK_00453 4.4e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
OOOKNECK_00454 4.4e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OOOKNECK_00455 3.3e-220 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OOOKNECK_00456 1.3e-62 ohrA O Organic hydroperoxide resistance protein
OOOKNECK_00457 7.5e-78 ohrR K COG1846 Transcriptional regulators
OOOKNECK_00458 7.9e-70 ohrB O Organic hydroperoxide resistance protein
OOOKNECK_00459 2.9e-51 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OOOKNECK_00461 6e-205 M Glycosyl transferase family 2
OOOKNECK_00462 3.1e-80 3.2.1.4 GH5,GH9 K Collagen triple helix repeat
OOOKNECK_00463 4e-207 hcaT 1.5.1.2 EGP Major facilitator Superfamily
OOOKNECK_00464 1e-117 yeiL T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
OOOKNECK_00465 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OOOKNECK_00466 6.8e-173 isp O Belongs to the peptidase S8 family
OOOKNECK_00467 3e-140 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOOKNECK_00468 7.1e-125 ykoC P Cobalt transport protein
OOOKNECK_00469 8.6e-277 P ABC transporter, ATP-binding protein
OOOKNECK_00470 9.3e-96 ykoE S ABC-type cobalt transport system, permease component
OOOKNECK_00471 7.9e-238 ydhD M Glycosyl hydrolase
OOOKNECK_00473 3e-235 mgtE P Acts as a magnesium transporter
OOOKNECK_00474 1.6e-52 tnrA K transcriptional
OOOKNECK_00475 1.9e-16
OOOKNECK_00476 5.9e-25 ykoL
OOOKNECK_00477 1.5e-80 ykoM K transcriptional
OOOKNECK_00478 4.1e-98 ykoP G polysaccharide deacetylase
OOOKNECK_00479 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
OOOKNECK_00480 2.8e-149 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
OOOKNECK_00481 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
OOOKNECK_00482 4.4e-95 ykoX S membrane-associated protein
OOOKNECK_00483 5.4e-128 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
OOOKNECK_00484 3.4e-127 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_00485 4.5e-118 rsgI S Anti-sigma factor N-terminus
OOOKNECK_00486 9.6e-26 sspD S small acid-soluble spore protein
OOOKNECK_00487 9.5e-124 ykrK S Domain of unknown function (DUF1836)
OOOKNECK_00488 3.9e-154 htpX O Belongs to the peptidase M48B family
OOOKNECK_00489 6.1e-236 ktrB P COG0168 Trk-type K transport systems, membrane components
OOOKNECK_00490 3e-111 ydfR S Protein of unknown function (DUF421)
OOOKNECK_00491 1.2e-19 ykzE
OOOKNECK_00492 3.8e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
OOOKNECK_00493 0.0 kinE 2.7.13.3 T Histidine kinase
OOOKNECK_00494 5.4e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OOOKNECK_00496 1e-190 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OOOKNECK_00497 1.6e-219 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OOOKNECK_00498 7.3e-138 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
OOOKNECK_00499 5.2e-223 mtnE 2.6.1.83 E Aminotransferase
OOOKNECK_00500 6.9e-223 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
OOOKNECK_00501 1.6e-131 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
OOOKNECK_00502 1.2e-109 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
OOOKNECK_00503 3.6e-91 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OOOKNECK_00504 4e-11 S Spo0E like sporulation regulatory protein
OOOKNECK_00505 2.1e-269 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOOKNECK_00506 3.2e-77 ykvE K transcriptional
OOOKNECK_00507 1.7e-121 motB N Flagellar motor protein
OOOKNECK_00508 2.5e-136 motA N flagellar motor
OOOKNECK_00509 0.0 clpE O Belongs to the ClpA ClpB family
OOOKNECK_00510 6.4e-177 ykvI S membrane
OOOKNECK_00511 4.9e-13
OOOKNECK_00512 9.3e-146
OOOKNECK_00513 1.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OOOKNECK_00514 2.9e-78 queD 4.1.2.50, 4.2.3.12 H synthase
OOOKNECK_00515 7.8e-137 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
OOOKNECK_00516 7.7e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OOOKNECK_00517 1.8e-41 ykvR S Protein of unknown function (DUF3219)
OOOKNECK_00518 1.7e-24 ykvS S protein conserved in bacteria
OOOKNECK_00519 2.3e-27
OOOKNECK_00520 1.1e-104 ykvT 3.5.1.28 M Cell Wall Hydrolase
OOOKNECK_00521 2.7e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_00522 2.4e-81 stoA CO thiol-disulfide
OOOKNECK_00523 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OOOKNECK_00524 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OOOKNECK_00525 1.9e-170 ykvZ 5.1.1.1 K Transcriptional regulator
OOOKNECK_00526 8.1e-154 glcT K antiterminator
OOOKNECK_00527 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_00528 2.1e-39 ptsH G phosphocarrier protein HPr
OOOKNECK_00529 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OOOKNECK_00530 6.7e-37 splA S Transcriptional regulator
OOOKNECK_00531 1.8e-192 splB 4.1.99.14 L Spore photoproduct lyase
OOOKNECK_00532 3.1e-255 mcpC NT chemotaxis protein
OOOKNECK_00533 2.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
OOOKNECK_00534 1.6e-48
OOOKNECK_00535 2.2e-113 ykwD J protein with SCP PR1 domains
OOOKNECK_00536 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
OOOKNECK_00537 1.3e-247 pilS 2.7.13.3 T PAS fold
OOOKNECK_00538 1.4e-48 pilS 2.1.1.80, 2.7.13.3, 3.1.1.61 T Histidine kinase
OOOKNECK_00539 5.7e-214 patA 2.6.1.1 E Aminotransferase
OOOKNECK_00540 1.4e-09
OOOKNECK_00541 2.2e-165 cheV 2.7.13.3 T Chemotaxis protein CheV
OOOKNECK_00542 3.2e-83 ykyB S YkyB-like protein
OOOKNECK_00543 2.9e-235 ykuC EGP Major facilitator Superfamily
OOOKNECK_00544 5.1e-87 ykuD S protein conserved in bacteria
OOOKNECK_00545 7.5e-147 ykuE S Metallophosphoesterase
OOOKNECK_00546 5.6e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_00548 2.4e-231 ykuI T Diguanylate phosphodiesterase
OOOKNECK_00549 2e-36 ykuJ S protein conserved in bacteria
OOOKNECK_00550 1.7e-90 ykuK S Ribonuclease H-like
OOOKNECK_00551 7.3e-26 ykzF S Antirepressor AbbA
OOOKNECK_00552 1e-75 ykuL S CBS domain
OOOKNECK_00553 2.3e-167 ccpC K Transcriptional regulator
OOOKNECK_00554 2.4e-86 fld C Flavodoxin
OOOKNECK_00555 8.6e-162 ykuO
OOOKNECK_00556 1.3e-73 fld C Flavodoxin
OOOKNECK_00557 4.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
OOOKNECK_00558 6.7e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
OOOKNECK_00559 1.8e-37 ykuS S Belongs to the UPF0180 family
OOOKNECK_00560 1.6e-138 ykuT M Mechanosensitive ion channel
OOOKNECK_00562 5.5e-72 ykuV CO thiol-disulfide
OOOKNECK_00564 3.8e-97 rok K Repressor of ComK
OOOKNECK_00565 3.3e-146 yknT
OOOKNECK_00566 2.2e-100 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
OOOKNECK_00567 4.1e-184 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
OOOKNECK_00568 1.5e-239 moeA 2.10.1.1 H molybdopterin
OOOKNECK_00569 1.7e-85 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
OOOKNECK_00570 6e-82 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
OOOKNECK_00571 4.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OOOKNECK_00572 1.6e-99 yknW S Yip1 domain
OOOKNECK_00573 9.9e-155 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OOOKNECK_00574 5.1e-122 macB V ABC transporter, ATP-binding protein
OOOKNECK_00575 4e-207 yknZ V ABC transporter (permease)
OOOKNECK_00576 4.3e-130 fruR K Transcriptional regulator
OOOKNECK_00577 7.1e-164 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
OOOKNECK_00578 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
OOOKNECK_00579 1.5e-106 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OOOKNECK_00580 6.4e-36 ykoA
OOOKNECK_00581 5.5e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOOKNECK_00582 1.3e-157 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OOOKNECK_00583 9.5e-236 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
OOOKNECK_00584 1.1e-12 S Uncharacterized protein YkpC
OOOKNECK_00585 7.7e-183 mreB D Rod-share determining protein MreBH
OOOKNECK_00586 1e-44 abrB K of stationary sporulation gene expression
OOOKNECK_00587 9.1e-237 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOOKNECK_00588 1.6e-146 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
OOOKNECK_00589 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
OOOKNECK_00590 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
OOOKNECK_00591 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OOOKNECK_00592 5.3e-30 ykzG S Belongs to the UPF0356 family
OOOKNECK_00593 2.5e-141 ykrA S hydrolases of the HAD superfamily
OOOKNECK_00594 1.6e-97 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OOOKNECK_00596 3e-66 recN L Putative cell-wall binding lipoprotein
OOOKNECK_00597 3.8e-183 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOOKNECK_00598 1.2e-177 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOOKNECK_00599 2.1e-225 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOOKNECK_00600 2.7e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOOKNECK_00601 6.1e-45 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
OOOKNECK_00602 1.4e-126 pdaA_2 3.5.1.104 G Polysaccharide deacetylase
OOOKNECK_00603 1.5e-272 speA 4.1.1.19 E Arginine
OOOKNECK_00604 5.9e-42 yktA S Belongs to the UPF0223 family
OOOKNECK_00605 1.8e-118 yktB S Belongs to the UPF0637 family
OOOKNECK_00606 6.3e-24 ykzI
OOOKNECK_00607 5.1e-150 suhB 3.1.3.25 G Inositol monophosphatase
OOOKNECK_00608 1.6e-70 ykzC S Acetyltransferase (GNAT) family
OOOKNECK_00609 5.1e-287 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
OOOKNECK_00610 5.6e-26 ylaA
OOOKNECK_00611 4.4e-14 sigC S Putative zinc-finger
OOOKNECK_00612 5.9e-37 ylaE
OOOKNECK_00613 6.7e-24 S Family of unknown function (DUF5325)
OOOKNECK_00614 0.0 typA T GTP-binding protein TypA
OOOKNECK_00615 6.6e-48 ylaH S YlaH-like protein
OOOKNECK_00616 1.5e-32 ylaI S protein conserved in bacteria
OOOKNECK_00617 1.6e-12 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOOKNECK_00618 3.4e-67 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOOKNECK_00619 7.8e-244 phoH T ATPase related to phosphate starvation-inducible protein PhoH
OOOKNECK_00620 5.7e-80 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OOOKNECK_00621 3.4e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
OOOKNECK_00622 8.7e-44 ylaN S Belongs to the UPF0358 family
OOOKNECK_00623 1.1e-209 ftsW D Belongs to the SEDS family
OOOKNECK_00624 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
OOOKNECK_00625 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
OOOKNECK_00626 4.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OOOKNECK_00627 2.6e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
OOOKNECK_00628 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OOOKNECK_00629 1.5e-109 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
OOOKNECK_00630 2.7e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
OOOKNECK_00631 1.9e-161 ctaG S cytochrome c oxidase
OOOKNECK_00632 4.6e-58 ylbA S YugN-like family
OOOKNECK_00633 1.2e-71 ylbB T COG0517 FOG CBS domain
OOOKNECK_00634 6.4e-193 ylbC S protein with SCP PR1 domains
OOOKNECK_00635 1.5e-52 ylbD S Putative coat protein
OOOKNECK_00636 8.8e-37 ylbE S YlbE-like protein
OOOKNECK_00637 2.5e-69 ylbF S Belongs to the UPF0342 family
OOOKNECK_00638 1e-41 ylbG S UPF0298 protein
OOOKNECK_00639 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
OOOKNECK_00640 2.1e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OOOKNECK_00641 5.2e-210 ylbJ S Sporulation integral membrane protein YlbJ
OOOKNECK_00642 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
OOOKNECK_00643 2.6e-183 ylbL T Belongs to the peptidase S16 family
OOOKNECK_00644 1.5e-220 ylbM S Belongs to the UPF0348 family
OOOKNECK_00645 5.6e-89 yceD S metal-binding, possibly nucleic acid-binding protein
OOOKNECK_00646 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
OOOKNECK_00647 5e-70 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
OOOKNECK_00648 5.8e-88 ylbP K n-acetyltransferase
OOOKNECK_00649 3.7e-152 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OOOKNECK_00650 1.9e-300 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
OOOKNECK_00651 1.2e-77 mraZ K Belongs to the MraZ family
OOOKNECK_00652 5.6e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
OOOKNECK_00653 2.4e-51 ftsL D Essential cell division protein
OOOKNECK_00654 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
OOOKNECK_00655 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
OOOKNECK_00656 9.8e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OOOKNECK_00657 1.4e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OOOKNECK_00658 6.7e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OOOKNECK_00659 2.2e-185 spoVE D Belongs to the SEDS family
OOOKNECK_00660 1.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OOOKNECK_00661 1.3e-165 murB 1.3.1.98 M cell wall formation
OOOKNECK_00662 3.9e-126 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
OOOKNECK_00663 1.7e-227 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
OOOKNECK_00664 7.5e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OOOKNECK_00665 0.0 bpr O COG1404 Subtilisin-like serine proteases
OOOKNECK_00666 7.8e-158 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
OOOKNECK_00667 1.2e-116 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_00668 3.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_00669 7.9e-143 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
OOOKNECK_00670 7e-242 argE 3.5.1.16 E Acetylornithine deacetylase
OOOKNECK_00671 2.2e-38 ylmC S sporulation protein
OOOKNECK_00672 5.2e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
OOOKNECK_00673 4.1e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OOOKNECK_00674 5.7e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
OOOKNECK_00675 5.2e-41 yggT S membrane
OOOKNECK_00676 6.3e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
OOOKNECK_00677 8.9e-68 divIVA D Cell division initiation protein
OOOKNECK_00678 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OOOKNECK_00679 3.8e-63 dksA T COG1734 DnaK suppressor protein
OOOKNECK_00680 1.7e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OOOKNECK_00681 1.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
OOOKNECK_00682 1e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
OOOKNECK_00683 1.1e-229 pyrP F Xanthine uracil
OOOKNECK_00684 1.7e-160 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OOOKNECK_00685 2.2e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OOOKNECK_00686 3.7e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
OOOKNECK_00687 0.0 carB 6.3.5.5 F Belongs to the CarB family
OOOKNECK_00688 1.1e-138 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
OOOKNECK_00689 1.6e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
OOOKNECK_00690 1.7e-123 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
OOOKNECK_00691 6.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OOOKNECK_00692 6.1e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
OOOKNECK_00693 8e-175 cysP P phosphate transporter
OOOKNECK_00694 3.6e-221 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
OOOKNECK_00695 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
OOOKNECK_00696 1.4e-139 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OOOKNECK_00697 3.2e-136 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
OOOKNECK_00698 4.3e-75 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
OOOKNECK_00699 7.4e-270 amyA 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
OOOKNECK_00700 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
OOOKNECK_00701 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
OOOKNECK_00702 6.7e-151 yloC S stress-induced protein
OOOKNECK_00703 1.5e-40 ylzA S Belongs to the UPF0296 family
OOOKNECK_00704 1.2e-109 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
OOOKNECK_00705 2.8e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
OOOKNECK_00706 4.5e-222 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OOOKNECK_00707 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OOOKNECK_00708 4.7e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
OOOKNECK_00709 6.4e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OOOKNECK_00710 4.9e-246 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OOOKNECK_00711 7.6e-205 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
OOOKNECK_00712 3.5e-132 stp 3.1.3.16 T phosphatase
OOOKNECK_00713 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
OOOKNECK_00714 2.7e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
OOOKNECK_00715 1.3e-114 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
OOOKNECK_00716 1.8e-113 thiN 2.7.6.2 H thiamine pyrophosphokinase
OOOKNECK_00717 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
OOOKNECK_00718 6.1e-58 asp S protein conserved in bacteria
OOOKNECK_00719 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
OOOKNECK_00720 4.8e-117 sdaAB 4.3.1.17 E L-serine dehydratase
OOOKNECK_00721 3.9e-154 sdaAA 4.3.1.17 E L-serine dehydratase
OOOKNECK_00722 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OOOKNECK_00723 2.2e-91 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
OOOKNECK_00724 2.3e-176 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
OOOKNECK_00725 1.9e-167 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOOKNECK_00726 1.1e-127 IQ reductase
OOOKNECK_00727 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
OOOKNECK_00728 7.5e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
OOOKNECK_00729 0.0 smc D Required for chromosome condensation and partitioning
OOOKNECK_00730 5.9e-172 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
OOOKNECK_00731 4.3e-50 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
OOOKNECK_00732 9e-232 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OOOKNECK_00733 1.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
OOOKNECK_00734 1.7e-35 ylqC S Belongs to the UPF0109 family
OOOKNECK_00735 1.1e-60 ylqD S YlqD protein
OOOKNECK_00736 1.4e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OOOKNECK_00737 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
OOOKNECK_00738 1.9e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
OOOKNECK_00739 5.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OOOKNECK_00740 5.5e-125 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OOOKNECK_00741 1.4e-266 ylqG
OOOKNECK_00742 1.6e-42 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
OOOKNECK_00743 2.6e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
OOOKNECK_00744 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OOOKNECK_00745 1.7e-162 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
OOOKNECK_00746 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OOOKNECK_00747 5.3e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
OOOKNECK_00748 3.3e-169 xerC L tyrosine recombinase XerC
OOOKNECK_00749 2.2e-91 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OOOKNECK_00750 2e-229 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OOOKNECK_00751 2e-135 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
OOOKNECK_00752 7.8e-51 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
OOOKNECK_00753 9.9e-74 flgC N Belongs to the flagella basal body rod proteins family
OOOKNECK_00754 2.5e-31 fliE N Flagellar hook-basal body
OOOKNECK_00755 2.7e-251 fliF N The M ring may be actively involved in energy transduction
OOOKNECK_00756 1.7e-177 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OOOKNECK_00757 1.4e-85 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
OOOKNECK_00758 2.7e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
OOOKNECK_00759 4.5e-71 fliJ N Flagellar biosynthesis chaperone
OOOKNECK_00760 1.2e-37 ylxF S MgtE intracellular N domain
OOOKNECK_00761 5.5e-189 fliK N Flagellar hook-length control protein
OOOKNECK_00762 2.7e-68 flgD N Flagellar basal body rod modification protein
OOOKNECK_00763 5.4e-136 flgG N Flagellar basal body rod
OOOKNECK_00764 5.1e-56 fliL N Controls the rotational direction of flagella during chemotaxis
OOOKNECK_00765 2.3e-179 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
OOOKNECK_00766 3.8e-175 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OOOKNECK_00767 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
OOOKNECK_00768 3.3e-110 fliZ N Flagellar biosynthesis protein, FliO
OOOKNECK_00769 3.7e-109 fliP N Plays a role in the flagellum-specific transport system
OOOKNECK_00770 7.5e-37 fliQ N Role in flagellar biosynthesis
OOOKNECK_00771 3.2e-128 fliR N Flagellar biosynthetic protein FliR
OOOKNECK_00772 1.1e-187 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OOOKNECK_00773 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OOOKNECK_00774 2.9e-156 flhF N Flagellar biosynthesis regulator FlhF
OOOKNECK_00775 4.3e-153 flhG D Belongs to the ParA family
OOOKNECK_00776 1.1e-187 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
OOOKNECK_00777 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
OOOKNECK_00778 2.5e-80 cheW NT COG0835 Chemotaxis signal transduction protein
OOOKNECK_00779 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
OOOKNECK_00780 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
OOOKNECK_00781 3.9e-139 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_00782 1.7e-47 ylxL
OOOKNECK_00783 3.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
OOOKNECK_00784 1.2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OOOKNECK_00785 1.6e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
OOOKNECK_00786 2.1e-89 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
OOOKNECK_00787 1.3e-142 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OOOKNECK_00788 8.4e-137 cdsA 2.7.7.41 S Belongs to the CDS family
OOOKNECK_00789 2.3e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
OOOKNECK_00790 4.2e-231 rasP M zinc metalloprotease
OOOKNECK_00791 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
OOOKNECK_00792 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OOOKNECK_00793 1.9e-80 rimP S Required for maturation of 30S ribosomal subunits
OOOKNECK_00794 3.5e-205 nusA K Participates in both transcription termination and antitermination
OOOKNECK_00795 1.7e-36 ylxR K nucleic-acid-binding protein implicated in transcription termination
OOOKNECK_00796 1.8e-47 ylxQ J ribosomal protein
OOOKNECK_00797 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OOOKNECK_00798 8.6e-44 ylxP S protein conserved in bacteria
OOOKNECK_00799 3.7e-51 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OOOKNECK_00800 2.4e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OOOKNECK_00801 1.9e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
OOOKNECK_00802 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OOOKNECK_00803 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
OOOKNECK_00804 1.4e-178 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
OOOKNECK_00805 2e-233 pepR S Belongs to the peptidase M16 family
OOOKNECK_00806 2.6e-42 ymxH S YlmC YmxH family
OOOKNECK_00807 9.8e-158 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
OOOKNECK_00808 4.3e-101 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
OOOKNECK_00809 1.1e-189 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OOOKNECK_00810 7.4e-217 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OOOKNECK_00811 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OOOKNECK_00812 4.7e-302 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
OOOKNECK_00813 6.6e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
OOOKNECK_00814 2.6e-29 S YlzJ-like protein
OOOKNECK_00815 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
OOOKNECK_00816 2e-129 ymfC K Transcriptional regulator
OOOKNECK_00817 6.2e-225 ymfD EGP Major facilitator Superfamily
OOOKNECK_00818 5.8e-74 K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_00819 0.0 ydgH S drug exporters of the RND superfamily
OOOKNECK_00820 7e-234 ymfF S Peptidase M16
OOOKNECK_00821 7.3e-239 ymfH S zinc protease
OOOKNECK_00822 8.1e-126 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
OOOKNECK_00823 9.7e-42 ymfJ S Protein of unknown function (DUF3243)
OOOKNECK_00824 5.1e-142 ymfK S Protein of unknown function (DUF3388)
OOOKNECK_00825 6.4e-117 ymfM S protein conserved in bacteria
OOOKNECK_00826 4.2e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OOOKNECK_00827 2.1e-230 cinA 3.5.1.42 S Belongs to the CinA family
OOOKNECK_00828 7.6e-186 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OOOKNECK_00830 4.2e-161 pbpX V Beta-lactamase
OOOKNECK_00831 4.2e-241 rny S Endoribonuclease that initiates mRNA decay
OOOKNECK_00832 1.9e-152 ymdB S protein conserved in bacteria
OOOKNECK_00833 1.2e-36 spoVS S Stage V sporulation protein S
OOOKNECK_00834 3.1e-195 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
OOOKNECK_00835 7e-212 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OOOKNECK_00836 6.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OOOKNECK_00837 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
OOOKNECK_00838 2.1e-86 cotE S Spore coat protein
OOOKNECK_00839 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OOOKNECK_00840 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OOOKNECK_00841 2.9e-125 pksB 3.1.2.6 S Polyketide biosynthesis
OOOKNECK_00842 8.6e-159 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOOKNECK_00843 6.9e-173 pksD Q Acyl transferase domain
OOOKNECK_00844 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOOKNECK_00845 8.5e-35 acpK IQ Phosphopantetheine attachment site
OOOKNECK_00846 1.5e-241 pksG 2.3.3.10 I synthase
OOOKNECK_00847 8.8e-139 pksH 4.2.1.18 I enoyl-CoA hydratase
OOOKNECK_00848 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
OOOKNECK_00849 1.4e-142 rhiB IQ polyketide synthase
OOOKNECK_00850 0.0 rhiB IQ polyketide synthase
OOOKNECK_00851 0.0 rhiB IQ polyketide synthase
OOOKNECK_00852 0.0 Q Polyketide synthase of type I
OOOKNECK_00853 0.0 pfaA 4.1.1.35 GT4 Q Polyketide synthase of type I
OOOKNECK_00854 1e-157 dhbF IQ polyketide synthase
OOOKNECK_00855 0.0 dhbF IQ polyketide synthase
OOOKNECK_00856 0.0 pks13 HQ Beta-ketoacyl synthase
OOOKNECK_00857 1.4e-223 cypA C Cytochrome P450
OOOKNECK_00858 5.2e-72 nucB M Deoxyribonuclease NucA/NucB
OOOKNECK_00859 3.4e-116 yoaK S Membrane
OOOKNECK_00860 1.6e-61 ymzB
OOOKNECK_00861 3.1e-248 aprX O Belongs to the peptidase S8 family
OOOKNECK_00863 1e-117 ymaC S Replication protein
OOOKNECK_00864 1.4e-75 ymaD O redox protein, regulator of disulfide bond formation
OOOKNECK_00865 9.8e-53 ebrB P Small Multidrug Resistance protein
OOOKNECK_00866 2.5e-47 ebrA P Small Multidrug Resistance protein
OOOKNECK_00868 1.4e-42 ymaF S YmaF family
OOOKNECK_00869 6.7e-165 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OOOKNECK_00870 1.1e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
OOOKNECK_00871 2.6e-40
OOOKNECK_00872 7.9e-21 ymzA
OOOKNECK_00873 2.3e-58 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
OOOKNECK_00874 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OOOKNECK_00875 2.6e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OOOKNECK_00876 1.3e-103 ymaB S MutT family
OOOKNECK_00878 4.1e-88 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_00879 8.6e-176 spoVK O stage V sporulation protein K
OOOKNECK_00880 8.2e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OOOKNECK_00881 5e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
OOOKNECK_00882 8.8e-66 glnR K transcriptional
OOOKNECK_00883 1.2e-260 glnA 6.3.1.2 E glutamine synthetase
OOOKNECK_00885 1.3e-12
OOOKNECK_00886 3.9e-116 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
OOOKNECK_00887 5.6e-212 cypA C Cytochrome P450
OOOKNECK_00888 5.1e-246 xynT G MFS/sugar transport protein
OOOKNECK_00889 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
OOOKNECK_00890 9.6e-206 xylR GK ROK family
OOOKNECK_00891 2.2e-254 xylA 5.3.1.5 G Belongs to the xylose isomerase family
OOOKNECK_00892 1.8e-273 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
OOOKNECK_00893 1.5e-116 3.2.1.8 G Glycosyl hydrolases family 11
OOOKNECK_00894 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
OOOKNECK_00895 1.3e-88 K Transcriptional regulator, TetR family
OOOKNECK_00896 2.2e-177 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OOOKNECK_00898 2.5e-195 S aspartate phosphatase
OOOKNECK_00901 1.7e-66 S DinB family
OOOKNECK_00902 8.5e-182 adhP 1.1.1.1 C alcohol dehydrogenase
OOOKNECK_00903 4e-11
OOOKNECK_00905 2.9e-26 S Protein of unknown function (DUF4025)
OOOKNECK_00906 1.1e-10 ywlA S Uncharacterised protein family (UPF0715)
OOOKNECK_00907 1.1e-128 yoaP 3.1.3.18 K YoaP-like
OOOKNECK_00908 1.1e-90 J Acetyltransferase (GNAT) domain
OOOKNECK_00910 1.4e-34
OOOKNECK_00912 6.6e-100 ynaE S Domain of unknown function (DUF3885)
OOOKNECK_00913 1.4e-187 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_00914 1.1e-115 AA10,CBM73 S Pfam:Chitin_bind_3
OOOKNECK_00916 3.3e-84 yvgO
OOOKNECK_00918 0.0 yobO M Pectate lyase superfamily protein
OOOKNECK_00919 1.3e-32 S TM2 domain
OOOKNECK_00920 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
OOOKNECK_00921 3.9e-24 S Domain of unknown function (DUF4177)
OOOKNECK_00922 9.7e-128 yndL S Replication protein
OOOKNECK_00924 2.5e-125 O COG0330 Membrane protease subunits, stomatin prohibitin homologs
OOOKNECK_00925 5.8e-66 yndM S Protein of unknown function (DUF2512)
OOOKNECK_00926 1.3e-11 yoaW
OOOKNECK_00927 9e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OOOKNECK_00928 1.2e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
OOOKNECK_00929 1.6e-109 yneB L resolvase
OOOKNECK_00930 9.8e-33 ynzC S UPF0291 protein
OOOKNECK_00931 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OOOKNECK_00932 7.7e-79 yneE S Sporulation inhibitor of replication protein sirA
OOOKNECK_00933 2.3e-28 yneF S UPF0154 protein
OOOKNECK_00934 8.9e-23 ynzD S Spo0E like sporulation regulatory protein
OOOKNECK_00935 1.2e-121 ccdA O cytochrome c biogenesis protein
OOOKNECK_00936 1.2e-56 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
OOOKNECK_00937 5.6e-75 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
OOOKNECK_00938 2.8e-70 yneK S Protein of unknown function (DUF2621)
OOOKNECK_00939 5.7e-59 hspX O Spore coat protein
OOOKNECK_00940 2.3e-19 sspP S Belongs to the SspP family
OOOKNECK_00941 7.5e-15 sspO S Belongs to the SspO family
OOOKNECK_00942 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OOOKNECK_00943 3e-136 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
OOOKNECK_00944 3.6e-88 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OOOKNECK_00946 1.1e-31 tlp S Belongs to the Tlp family
OOOKNECK_00947 7.7e-73 yneP S Thioesterase-like superfamily
OOOKNECK_00948 1.9e-49 yneQ
OOOKNECK_00949 3.4e-43 yneR S Belongs to the HesB IscA family
OOOKNECK_00950 4.2e-93 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
OOOKNECK_00951 3.3e-68 yccU S CoA-binding protein
OOOKNECK_00952 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OOOKNECK_00953 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
OOOKNECK_00954 4.6e-13
OOOKNECK_00955 1.2e-39 ynfC
OOOKNECK_00956 4e-246 agcS E Sodium alanine symporter
OOOKNECK_00957 5.2e-22 yndG S DoxX-like family
OOOKNECK_00958 2e-77 yndH S Domain of unknown function (DUF4166)
OOOKNECK_00959 4.6e-275 yndJ S YndJ-like protein
OOOKNECK_00960 1.2e-49 S Domain of unknown function (DUF4870)
OOOKNECK_00961 3.2e-216 T PhoQ Sensor
OOOKNECK_00962 9e-122 T Transcriptional regulatory protein, C terminal
OOOKNECK_00963 5.5e-239 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
OOOKNECK_00964 1.5e-278 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
OOOKNECK_00965 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00966 0.0 Q Non-ribosomal peptide synthetase modules and related proteins
OOOKNECK_00967 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00968 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00969 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00970 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00971 4.5e-206 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
OOOKNECK_00972 2e-122 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
OOOKNECK_00973 1.1e-105 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OOOKNECK_00974 2.3e-114 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OOOKNECK_00975 2.5e-164 bioI 1.14.14.46 C Cytochrome P450
OOOKNECK_00976 8.5e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OOOKNECK_00977 4e-122 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OOOKNECK_00978 3.9e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
OOOKNECK_00979 1.6e-252 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
OOOKNECK_00980 8.5e-134 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
OOOKNECK_00981 1.6e-67 yngA S membrane
OOOKNECK_00982 8.6e-154 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OOOKNECK_00983 1.6e-103 yngC S SNARE associated Golgi protein
OOOKNECK_00984 1.1e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OOOKNECK_00985 5.6e-133 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OOOKNECK_00986 1.6e-163 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
OOOKNECK_00987 1.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
OOOKNECK_00988 9e-240 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
OOOKNECK_00989 5.9e-310 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OOOKNECK_00990 5e-207 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
OOOKNECK_00991 5.6e-294 yngK T Glycosyl hydrolase-like 10
OOOKNECK_00992 5.1e-63 yngL S Protein of unknown function (DUF1360)
OOOKNECK_00993 0.0 Q D-alanine [D-alanyl carrier protein] ligase activity
OOOKNECK_00994 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_00995 3.1e-257 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
OOOKNECK_00996 3.4e-180 yoxA 5.1.3.3 G Aldose 1-epimerase
OOOKNECK_00997 3.8e-241 yoeA V MATE efflux family protein
OOOKNECK_00998 1.6e-94 yoeB S IseA DL-endopeptidase inhibitor
OOOKNECK_01000 1.9e-95 L Integrase
OOOKNECK_01001 1.1e-33 yoeD G Helix-turn-helix domain
OOOKNECK_01002 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OOOKNECK_01003 1.2e-190 ybcL EGP Major facilitator Superfamily
OOOKNECK_01004 6.7e-50 ybzH K Helix-turn-helix domain
OOOKNECK_01005 1.5e-225 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OOOKNECK_01006 4.4e-30 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OOOKNECK_01007 3.6e-290 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
OOOKNECK_01008 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
OOOKNECK_01009 3.6e-147 gltC K Transcriptional regulator
OOOKNECK_01010 5.1e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OOOKNECK_01011 6.1e-135 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOOKNECK_01012 3.6e-61 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
OOOKNECK_01013 6.9e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01014 1.3e-37 yoxC S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OOOKNECK_01015 1.7e-115 yoxB
OOOKNECK_01016 2.7e-92 thiT S Thiamine transporter protein (Thia_YuaJ)
OOOKNECK_01017 6.1e-176 yuaG 3.4.21.72 S protein conserved in bacteria
OOOKNECK_01018 2.6e-81 yuaF OU Membrane protein implicated in regulation of membrane protease activity
OOOKNECK_01019 2.2e-79 yuaE S DinB superfamily
OOOKNECK_01020 1.2e-103 yuaD S MOSC domain
OOOKNECK_01021 6.7e-226 gbsB 1.1.1.1 C alcohol dehydrogenase
OOOKNECK_01022 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
OOOKNECK_01023 3.4e-92 yuaC K Belongs to the GbsR family
OOOKNECK_01024 4.3e-92 yuaB
OOOKNECK_01025 4.8e-117 ktrA P COG0569 K transport systems, NAD-binding component
OOOKNECK_01026 9.3e-142 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OOOKNECK_01027 5.2e-207 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OOOKNECK_01028 1.7e-36 G Cupin
OOOKNECK_01029 1.1e-42 yjcN
OOOKNECK_01032 2.4e-132 S Aspartate phosphatase response regulator
OOOKNECK_01033 4e-14
OOOKNECK_01035 2.8e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
OOOKNECK_01036 5.5e-193 yubA S transporter activity
OOOKNECK_01037 9.1e-181 ygjR S Oxidoreductase
OOOKNECK_01038 1.5e-97 pfpI 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
OOOKNECK_01039 5.3e-228 mcpA NT chemotaxis protein
OOOKNECK_01040 6.9e-220 mcpA NT chemotaxis protein
OOOKNECK_01041 1.3e-213 mcpA NT chemotaxis protein
OOOKNECK_01042 9.4e-132 mcpA NT chemotaxis protein
OOOKNECK_01043 8.4e-38 mcpA NT chemotaxis protein
OOOKNECK_01044 3.3e-135 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
OOOKNECK_01045 5.8e-39
OOOKNECK_01046 3.6e-186 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
OOOKNECK_01047 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
OOOKNECK_01048 8.1e-230 yugS S COG1253 Hemolysins and related proteins containing CBS domains
OOOKNECK_01049 4.1e-116 yugP S Zn-dependent protease
OOOKNECK_01050 6.5e-17
OOOKNECK_01051 1e-27 mstX S Membrane-integrating protein Mistic
OOOKNECK_01052 1.6e-177 yugO P COG1226 Kef-type K transport systems
OOOKNECK_01053 5e-69 yugN S YugN-like family
OOOKNECK_01055 1.9e-258 pgi 5.3.1.9 G Belongs to the GPI family
OOOKNECK_01056 5.8e-227 yugK C Dehydrogenase
OOOKNECK_01057 1e-223 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
OOOKNECK_01058 6.8e-34 yuzA S Domain of unknown function (DUF378)
OOOKNECK_01059 2.9e-61 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
OOOKNECK_01060 3e-207 yugH 2.6.1.1 E Aminotransferase
OOOKNECK_01061 5.8e-83 alaR K Transcriptional regulator
OOOKNECK_01062 2e-149 yugF I Hydrolase
OOOKNECK_01063 5e-38 yugE S Domain of unknown function (DUF1871)
OOOKNECK_01064 6.4e-218 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
OOOKNECK_01065 2.9e-219 T PhoQ Sensor
OOOKNECK_01066 7.4e-62 kapB G Kinase associated protein B
OOOKNECK_01067 1.6e-115 kapD L the KinA pathway to sporulation
OOOKNECK_01068 1.5e-165 yuxJ EGP Major facilitator Superfamily
OOOKNECK_01069 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
OOOKNECK_01070 1e-69 yuxK S protein conserved in bacteria
OOOKNECK_01071 1.1e-71 yufK S Family of unknown function (DUF5366)
OOOKNECK_01072 6.4e-31 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOOKNECK_01073 3.8e-246 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOOKNECK_01074 8.7e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
OOOKNECK_01075 5.1e-193 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
OOOKNECK_01076 1.7e-279 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
OOOKNECK_01077 7.4e-181 yufP S Belongs to the binding-protein-dependent transport system permease family
OOOKNECK_01078 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
OOOKNECK_01079 9.8e-11
OOOKNECK_01080 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
OOOKNECK_01081 6.6e-67 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOOKNECK_01082 2.2e-49 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOOKNECK_01083 7.4e-259 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOOKNECK_01084 5.5e-75 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOOKNECK_01085 1.4e-36 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
OOOKNECK_01086 9.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
OOOKNECK_01087 2.6e-59 ydiI Q protein, possibly involved in aromatic compounds catabolism
OOOKNECK_01088 1e-45 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_01089 6.6e-47 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_01090 4.2e-253 comP 2.7.13.3 T Histidine kinase
OOOKNECK_01092 2.9e-61 comQ H Belongs to the FPP GGPP synthase family
OOOKNECK_01094 1.6e-47 yuzC
OOOKNECK_01095 8.2e-224 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
OOOKNECK_01096 1.7e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OOOKNECK_01097 3e-101 pncA Q COG1335 Amidases related to nicotinamidase
OOOKNECK_01098 1.1e-65 yueI S Protein of unknown function (DUF1694)
OOOKNECK_01099 4.8e-38 yueH S YueH-like protein
OOOKNECK_01100 7.1e-33 yueG S Spore germination protein gerPA/gerPF
OOOKNECK_01101 1.4e-182 yueF S transporter activity
OOOKNECK_01102 1.6e-22 S Protein of unknown function (DUF2642)
OOOKNECK_01103 2.4e-95 yueE S phosphohydrolase
OOOKNECK_01104 3.4e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_01105 2.7e-74 yueC S Family of unknown function (DUF5383)
OOOKNECK_01106 0.0 esaA S type VII secretion protein EsaA
OOOKNECK_01107 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
OOOKNECK_01108 6.3e-198 essB S WXG100 protein secretion system (Wss), protein YukC
OOOKNECK_01109 9.6e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
OOOKNECK_01110 1.7e-45 esxA S Belongs to the WXG100 family
OOOKNECK_01111 6.8e-226 yukF QT Transcriptional regulator
OOOKNECK_01112 1.3e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
OOOKNECK_01113 1.9e-129 yukJ S Uncharacterized conserved protein (DUF2278)
OOOKNECK_01114 1.7e-31 mbtH S MbtH-like protein
OOOKNECK_01115 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_01116 2.3e-162 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
OOOKNECK_01117 3.6e-307 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
OOOKNECK_01118 5.8e-214 entC 5.4.4.2 HQ Isochorismate synthase
OOOKNECK_01119 2.2e-129 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01120 8.9e-156 besA S Putative esterase
OOOKNECK_01121 3e-118 yuiH S Oxidoreductase molybdopterin binding domain
OOOKNECK_01122 1.2e-100 bioY S Biotin biosynthesis protein
OOOKNECK_01123 1.5e-207 yuiF S antiporter
OOOKNECK_01124 1.2e-277 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OOOKNECK_01125 6.5e-76 yuiD S protein conserved in bacteria
OOOKNECK_01126 1.3e-114 yuiC S protein conserved in bacteria
OOOKNECK_01127 4.9e-27 yuiB S Putative membrane protein
OOOKNECK_01128 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
OOOKNECK_01129 1.8e-184 yumC 1.18.1.2, 1.19.1.1 C reductase
OOOKNECK_01131 3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
OOOKNECK_01132 2e-27
OOOKNECK_01133 8e-67 CP Membrane
OOOKNECK_01134 3.5e-118 V ABC transporter
OOOKNECK_01136 5.4e-32 S Bacteriocin class IId cyclical uberolysin-like
OOOKNECK_01138 6.6e-42 rimJ 2.3.1.128 J Alanine acetyltransferase
OOOKNECK_01139 1.3e-129 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01140 2.6e-61 erpA S Belongs to the HesB IscA family
OOOKNECK_01141 3.8e-159 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OOOKNECK_01142 3.6e-203 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOOKNECK_01143 1.7e-37 yuzB S Belongs to the UPF0349 family
OOOKNECK_01144 5.7e-205 yutJ 1.6.99.3 C NADH dehydrogenase
OOOKNECK_01145 4.1e-53 yuzD S protein conserved in bacteria
OOOKNECK_01146 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
OOOKNECK_01147 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
OOOKNECK_01148 3.1e-162 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
OOOKNECK_01149 4.5e-194 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OOOKNECK_01150 5.1e-240 hom 1.1.1.3 E homoserine dehydrogenase
OOOKNECK_01151 6.3e-193 yutH S Spore coat protein
OOOKNECK_01152 5.2e-84 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
OOOKNECK_01153 7.9e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
OOOKNECK_01154 8.9e-72 yutE S Protein of unknown function DUF86
OOOKNECK_01155 1.7e-47 yutD S protein conserved in bacteria
OOOKNECK_01156 8e-168 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OOOKNECK_01157 2.5e-191 lytH M Peptidase, M23
OOOKNECK_01158 1.1e-128 yunB S Sporulation protein YunB (Spo_YunB)
OOOKNECK_01159 1.2e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
OOOKNECK_01160 4.8e-143 yunE S membrane transporter protein
OOOKNECK_01161 9.9e-168 yunF S Protein of unknown function DUF72
OOOKNECK_01162 2.1e-55 3.1.3.18, 3.8.1.2 S phosphoglycolate phosphatase activity
OOOKNECK_01163 2.7e-252 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
OOOKNECK_01164 1.7e-293 pucR QT COG2508 Regulator of polyketide synthase expression
OOOKNECK_01165 2.8e-65
OOOKNECK_01166 2.4e-207 blt EGP Major facilitator Superfamily
OOOKNECK_01167 1.2e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
OOOKNECK_01168 6.4e-224 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
OOOKNECK_01169 3.7e-162 bsn L Ribonuclease
OOOKNECK_01170 7e-198 msmX P Belongs to the ABC transporter superfamily
OOOKNECK_01171 1.5e-132 yurK K UTRA
OOOKNECK_01172 2.5e-158 yurL 2.7.1.218 G pfkB family carbohydrate kinase
OOOKNECK_01173 2.4e-156 yurM P COG0395 ABC-type sugar transport system, permease component
OOOKNECK_01174 2.2e-157 yurN G Binding-protein-dependent transport system inner membrane component
OOOKNECK_01175 2.1e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
OOOKNECK_01176 5.3e-181 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
OOOKNECK_01177 8.3e-160 K helix_turn_helix, mercury resistance
OOOKNECK_01178 1e-14
OOOKNECK_01179 2.4e-77
OOOKNECK_01180 3.5e-22 S Sporulation delaying protein SdpA
OOOKNECK_01182 2.6e-64 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
OOOKNECK_01183 3.5e-197 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
OOOKNECK_01184 3.4e-101 Q ubiE/COQ5 methyltransferase family
OOOKNECK_01185 1.1e-72 yncE S Protein of unknown function (DUF2691)
OOOKNECK_01186 1.9e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
OOOKNECK_01187 8.7e-270 sufB O FeS cluster assembly
OOOKNECK_01188 8.5e-78 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
OOOKNECK_01189 2.8e-232 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OOOKNECK_01190 7e-245 sufD O assembly protein SufD
OOOKNECK_01191 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
OOOKNECK_01192 6.7e-09
OOOKNECK_01193 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OOOKNECK_01194 4e-142 metQ P Belongs to the NlpA lipoprotein family
OOOKNECK_01195 8.3e-93 metI P COG2011 ABC-type metal ion transport system, permease component
OOOKNECK_01196 1.1e-184 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OOOKNECK_01197 2.1e-55 yusD S SCP-2 sterol transfer family
OOOKNECK_01198 5.2e-53 yusE CO Thioredoxin
OOOKNECK_01199 1.3e-60 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
OOOKNECK_01200 2.1e-38 yusG S Protein of unknown function (DUF2553)
OOOKNECK_01201 5.5e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
OOOKNECK_01202 1.8e-62 arsC 1.20.4.1 P Belongs to the ArsC family
OOOKNECK_01203 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
OOOKNECK_01204 1e-215 fadA 2.3.1.16 I Belongs to the thiolase family
OOOKNECK_01205 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
OOOKNECK_01207 3e-148 fadM E Proline dehydrogenase
OOOKNECK_01208 3.5e-39
OOOKNECK_01209 1.3e-51 yusN M Coat F domain
OOOKNECK_01210 4.5e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
OOOKNECK_01211 5.4e-284 yusP P Major facilitator superfamily
OOOKNECK_01212 9.8e-59 L PFAM Restriction endonuclease BamHI
OOOKNECK_01213 1.8e-16 K Helix-turn-helix XRE-family like proteins
OOOKNECK_01214 2.2e-126 2.1.1.72 L DNA methylase
OOOKNECK_01215 8.1e-38 yusU S Protein of unknown function (DUF2573)
OOOKNECK_01216 3.1e-150 yusV 3.6.3.34 HP ABC transporter
OOOKNECK_01217 1e-46 S YusW-like protein
OOOKNECK_01218 0.0 pepF2 E COG1164 Oligoendopeptidase F
OOOKNECK_01219 3.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01220 1.5e-77 dps P Belongs to the Dps family
OOOKNECK_01221 3.5e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOOKNECK_01222 2.2e-99 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_01223 6.3e-249 cssS 2.7.13.3 T PhoQ Sensor
OOOKNECK_01224 1.3e-23
OOOKNECK_01225 3e-154 yuxN K Transcriptional regulator
OOOKNECK_01226 7.3e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
OOOKNECK_01227 6.6e-24 S Protein of unknown function (DUF3970)
OOOKNECK_01228 1.1e-254 gerAA EG Spore germination protein
OOOKNECK_01229 4.6e-181 gerAB E Spore germination protein
OOOKNECK_01230 7.6e-192 gerAC S Spore germination B3/ GerAC like, C-terminal
OOOKNECK_01231 5.6e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_01232 1.1e-192 vraS 2.7.13.3 T Histidine kinase
OOOKNECK_01233 4.4e-124 yvqF S Cell wall-active antibiotics response 4TMS YvqF
OOOKNECK_01234 2.1e-117 liaG S Putative adhesin
OOOKNECK_01235 8.7e-90 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
OOOKNECK_01236 6.9e-44 liaI S membrane
OOOKNECK_01237 1.2e-220 yvqJ EGP Major facilitator Superfamily
OOOKNECK_01238 2.3e-96 yvqK 2.5.1.17 S Adenosyltransferase
OOOKNECK_01239 3.1e-202 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
OOOKNECK_01240 1.4e-176 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_01241 1.1e-164 yvrC P ABC transporter substrate-binding protein
OOOKNECK_01242 1e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01243 4.3e-166 yvrE G SMP-30/Gluconolaconase/LRE-like region
OOOKNECK_01244 0.0 T PhoQ Sensor
OOOKNECK_01245 5.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_01246 6.2e-35
OOOKNECK_01247 2.1e-100 yvrI K RNA polymerase
OOOKNECK_01248 1.6e-15 S YvrJ protein family
OOOKNECK_01249 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
OOOKNECK_01250 9.9e-60 yvrL S Regulatory protein YrvL
OOOKNECK_01251 4.5e-146 fhuC 3.6.3.34 HP ABC transporter
OOOKNECK_01252 1.4e-168 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_01253 1.5e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_01254 5.8e-177 fhuD P ABC transporter
OOOKNECK_01255 4e-122 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
OOOKNECK_01256 3e-233 yvsH E Arginine ornithine antiporter
OOOKNECK_01257 5.2e-13 S Small spore protein J (Spore_SspJ)
OOOKNECK_01258 3e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
OOOKNECK_01259 1.1e-165 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOOKNECK_01260 3.5e-163 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOOKNECK_01261 5.4e-159 yvgK P COG1910 Periplasmic molybdate-binding protein domain
OOOKNECK_01262 4.2e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
OOOKNECK_01263 1.2e-99 modB P COG4149 ABC-type molybdate transport system, permease component
OOOKNECK_01264 3.3e-113 yfiK K Regulator
OOOKNECK_01265 5.6e-171 T Histidine kinase
OOOKNECK_01266 6.8e-170 yfiL V COG1131 ABC-type multidrug transport system, ATPase component
OOOKNECK_01267 3e-185 yfiM V ABC-2 type transporter
OOOKNECK_01268 7.3e-174 yfiN V COG0842 ABC-type multidrug transport system, permease component
OOOKNECK_01269 3.6e-154 yvgN S reductase
OOOKNECK_01270 6.6e-84 yvgO
OOOKNECK_01271 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
OOOKNECK_01272 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
OOOKNECK_01273 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OOOKNECK_01274 0.0 helD 3.6.4.12 L DNA helicase
OOOKNECK_01275 5.4e-99 yvgT S membrane
OOOKNECK_01276 1.6e-138 S Metallo-peptidase family M12
OOOKNECK_01277 6.6e-72 bdbC O Required for disulfide bond formation in some proteins
OOOKNECK_01278 5e-98 bdbD O Thioredoxin
OOOKNECK_01279 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
OOOKNECK_01280 0.0 copA 3.6.3.54 P P-type ATPase
OOOKNECK_01281 4.9e-28 copZ P Heavy-metal-associated domain
OOOKNECK_01282 7.6e-46 csoR S transcriptional
OOOKNECK_01283 6.6e-190 yvaA 1.1.1.371 S Oxidoreductase
OOOKNECK_01284 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOOKNECK_01285 2.4e-245 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_01286 2e-43 ytnI O COG0695 Glutaredoxin and related proteins
OOOKNECK_01287 9.3e-173 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_01288 5.2e-139 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOOKNECK_01289 1.9e-116 tcyM U Binding-protein-dependent transport system inner membrane component
OOOKNECK_01290 8e-118 tcyL P Binding-protein-dependent transport system inner membrane component
OOOKNECK_01291 3.3e-144 tcyK M Bacterial periplasmic substrate-binding proteins
OOOKNECK_01292 2.1e-127 ytmJ ET Bacterial periplasmic substrate-binding proteins
OOOKNECK_01293 5.7e-100 ytmI K Acetyltransferase (GNAT) domain
OOOKNECK_01294 1e-159 ytlI K LysR substrate binding domain
OOOKNECK_01295 7.7e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_01296 1.1e-41 yrdF K ribonuclease inhibitor
OOOKNECK_01298 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OOOKNECK_01299 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
OOOKNECK_01300 1.6e-142 est 3.1.1.1 S Carboxylesterase
OOOKNECK_01301 4.2e-20 secG U Preprotein translocase subunit SecG
OOOKNECK_01302 6e-35 yvzC K Transcriptional
OOOKNECK_01303 1.6e-67 K transcriptional
OOOKNECK_01304 9.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
OOOKNECK_01305 1.4e-50 yodB K transcriptional
OOOKNECK_01306 5.5e-240 T His Kinase A (phosphoacceptor) domain
OOOKNECK_01307 1.3e-119 K Transcriptional regulatory protein, C terminal
OOOKNECK_01308 6.8e-131 mutG S ABC-2 family transporter protein
OOOKNECK_01309 1e-120 spaE S ABC-2 family transporter protein
OOOKNECK_01310 1.6e-123 mutF V ABC transporter, ATP-binding protein
OOOKNECK_01311 4.4e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOOKNECK_01312 8.2e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OOOKNECK_01313 6.5e-97 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOOKNECK_01314 5.6e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OOOKNECK_01315 1.7e-56 yvbF K Belongs to the GbsR family
OOOKNECK_01316 4.1e-108 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOOKNECK_01317 7.4e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
OOOKNECK_01318 8.6e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
OOOKNECK_01319 9.7e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
OOOKNECK_01320 2.8e-94 yvbF K Belongs to the GbsR family
OOOKNECK_01321 4.4e-104 yvbG U UPF0056 membrane protein
OOOKNECK_01322 2.6e-113 exoY M Membrane
OOOKNECK_01323 0.0 tcaA S response to antibiotic
OOOKNECK_01324 1.4e-78 yvbK 3.1.3.25 K acetyltransferase
OOOKNECK_01325 7.8e-206 EGP Major facilitator Superfamily
OOOKNECK_01326 4.2e-172
OOOKNECK_01327 2e-123 S GlcNAc-PI de-N-acetylase
OOOKNECK_01328 2.4e-141 C WbqC-like protein family
OOOKNECK_01329 8.3e-141 M Protein involved in cellulose biosynthesis
OOOKNECK_01330 1.3e-219 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OOOKNECK_01331 5.9e-129 5.1.3.2 M GDP-mannose 4,6 dehydratase
OOOKNECK_01332 3.8e-18 5.1.3.2 M GDP-mannose 4,6 dehydratase
OOOKNECK_01333 7.6e-216 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OOOKNECK_01334 9.5e-250 1.1.1.136 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOOKNECK_01335 7.3e-223 ywaD 3.4.11.10, 3.4.11.6 S PA domain
OOOKNECK_01336 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
OOOKNECK_01337 6.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
OOOKNECK_01338 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
OOOKNECK_01339 1.6e-216 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
OOOKNECK_01340 2.1e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OOOKNECK_01341 8.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OOOKNECK_01342 2.3e-31 araE EGP Major facilitator Superfamily
OOOKNECK_01343 1.7e-208 araE EGP Major facilitator Superfamily
OOOKNECK_01344 7.4e-200 araR K transcriptional
OOOKNECK_01345 1.2e-188 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_01346 8.4e-125 yvbU K Transcriptional regulator
OOOKNECK_01347 2.8e-152 yvbV EG EamA-like transporter family
OOOKNECK_01348 3.2e-213 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_01350 6.7e-148 ybbH_1 K RpiR family transcriptional regulator
OOOKNECK_01351 6.6e-295 gntK 2.7.1.12, 2.7.1.17, 2.7.1.189 G Belongs to the FGGY kinase family
OOOKNECK_01352 2.3e-219 gntP EG COG2610 H gluconate symporter and related permeases
OOOKNECK_01353 3.5e-129 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OOOKNECK_01354 1.7e-265 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
OOOKNECK_01355 1.8e-133 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
OOOKNECK_01356 7.3e-136 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_01357 4.6e-61 EK COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_01358 1.4e-117 yvfI K COG2186 Transcriptional regulators
OOOKNECK_01359 3.8e-296 yvfH C L-lactate permease
OOOKNECK_01360 4.7e-39 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OOOKNECK_01361 1.6e-175 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
OOOKNECK_01362 2.7e-32 yvfG S YvfG protein
OOOKNECK_01363 2.3e-176 yvfF GM Exopolysaccharide biosynthesis protein
OOOKNECK_01364 2.7e-216 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
OOOKNECK_01365 1.1e-49 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
OOOKNECK_01366 1.8e-102 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OOOKNECK_01367 5.2e-268 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_01368 2e-186 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
OOOKNECK_01369 2e-197 epsI GM pyruvyl transferase
OOOKNECK_01370 4.6e-191 epsH GT2 S Glycosyltransferase like family 2
OOOKNECK_01371 1.4e-201 epsG S EpsG family
OOOKNECK_01372 3.8e-199 epsF GT4 M Glycosyl transferases group 1
OOOKNECK_01373 8.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOOKNECK_01374 3.6e-213 epsD GT4 M Glycosyl transferase 4-like
OOOKNECK_01375 9.3e-206 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OOOKNECK_01376 8.1e-113 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
OOOKNECK_01377 5.4e-116 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
OOOKNECK_01378 3.3e-116 ywqC M biosynthesis protein
OOOKNECK_01379 5.1e-78 slr K transcriptional
OOOKNECK_01380 6.5e-236 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
OOOKNECK_01382 1.3e-85 ywjB H RibD C-terminal domain
OOOKNECK_01383 1.7e-130 CH FAD binding domain
OOOKNECK_01384 9.3e-74 S Metallo-beta-lactamase superfamily
OOOKNECK_01385 3e-105 yyaS S Membrane
OOOKNECK_01386 1e-82 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOOKNECK_01387 1.2e-93 padC Q Phenolic acid decarboxylase
OOOKNECK_01388 9.4e-50 MA20_18690 S Protein of unknown function (DUF3237)
OOOKNECK_01389 6.1e-31 S Protein of unknown function (DUF1433)
OOOKNECK_01390 5e-17 S Protein of unknown function (DUF1433)
OOOKNECK_01391 4.8e-19 S Protein of unknown function (DUF1433)
OOOKNECK_01392 5.8e-253 I Pfam Lipase (class 3)
OOOKNECK_01393 7.6e-33
OOOKNECK_01395 1.8e-278 cscA 3.2.1.26, 3.2.1.65 GH32 G invertase
OOOKNECK_01396 7.8e-214 rafB P LacY proton/sugar symporter
OOOKNECK_01397 1.6e-177 scrR K transcriptional
OOOKNECK_01398 2.4e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
OOOKNECK_01399 7.2e-158 yraN K Transcriptional regulator
OOOKNECK_01400 3.7e-202 yraM S PrpF protein
OOOKNECK_01401 8.3e-241 EGP Sugar (and other) transporter
OOOKNECK_01402 5.3e-89
OOOKNECK_01403 6.4e-102 yvdD 3.2.2.10 S Belongs to the LOG family
OOOKNECK_01404 7.1e-50 yvdC S MazG nucleotide pyrophosphohydrolase domain
OOOKNECK_01405 6.4e-277 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
OOOKNECK_01406 4.1e-104 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OOOKNECK_01407 2.9e-179 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOOKNECK_01408 1.3e-76 M Ribonuclease
OOOKNECK_01409 1.5e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
OOOKNECK_01410 1.4e-35 crh G Phosphocarrier protein Chr
OOOKNECK_01411 3.1e-170 whiA K May be required for sporulation
OOOKNECK_01412 9.4e-175 ybhK S Required for morphogenesis under gluconeogenic growth conditions
OOOKNECK_01413 2.2e-165 rapZ S Displays ATPase and GTPase activities
OOOKNECK_01414 2.5e-86 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
OOOKNECK_01415 9.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
OOOKNECK_01416 3.3e-118 usp CBM50 M protein conserved in bacteria
OOOKNECK_01417 4.2e-267 S COG0457 FOG TPR repeat
OOOKNECK_01418 6.8e-182 sasA T Histidine kinase
OOOKNECK_01419 4.4e-118 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_01420 0.0 msbA2 3.6.3.44 V ABC transporter
OOOKNECK_01421 2.2e-108 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
OOOKNECK_01422 1.2e-135 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
OOOKNECK_01423 6.7e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OOOKNECK_01424 1.4e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OOOKNECK_01425 8.2e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
OOOKNECK_01426 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OOOKNECK_01427 1.4e-113 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
OOOKNECK_01428 9.4e-201 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
OOOKNECK_01429 7.2e-135 yvpB NU protein conserved in bacteria
OOOKNECK_01430 2.4e-79 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
OOOKNECK_01431 1.3e-111 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
OOOKNECK_01432 5.8e-149 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OOOKNECK_01433 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
OOOKNECK_01434 3.4e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
OOOKNECK_01435 4.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
OOOKNECK_01436 7.6e-132 yvoA K transcriptional
OOOKNECK_01437 3.2e-101 yxaF K Transcriptional regulator
OOOKNECK_01438 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
OOOKNECK_01439 9.1e-46 yvlD S Membrane
OOOKNECK_01440 9.6e-26 pspB KT PspC domain
OOOKNECK_01441 5.6e-163 yvlB S Putative adhesin
OOOKNECK_01442 4e-46 yvlA
OOOKNECK_01443 3.6e-30 yvkN
OOOKNECK_01444 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
OOOKNECK_01445 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
OOOKNECK_01446 7.6e-33 csbA S protein conserved in bacteria
OOOKNECK_01447 0.0 yvkC 2.7.9.2 GT Phosphotransferase
OOOKNECK_01448 1e-91 yvkB K Transcriptional regulator
OOOKNECK_01449 6.5e-222 yvkA EGP Major facilitator Superfamily
OOOKNECK_01450 4.5e-25 yuaB
OOOKNECK_01452 1e-215 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOOKNECK_01453 2.9e-54 swrA S Swarming motility protein
OOOKNECK_01454 1.3e-249 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
OOOKNECK_01455 9.6e-192 ywoF P Right handed beta helix region
OOOKNECK_01456 2.2e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
OOOKNECK_01457 2.3e-122 ftsE D cell division ATP-binding protein FtsE
OOOKNECK_01458 5.2e-35 cccB C COG2010 Cytochrome c, mono- and diheme variants
OOOKNECK_01459 1.5e-147 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_01460 9.4e-170 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
OOOKNECK_01461 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
OOOKNECK_01462 4.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OOOKNECK_01463 6.8e-68
OOOKNECK_01464 1.3e-09 fliT S bacterial-type flagellum organization
OOOKNECK_01465 7e-63 fliS N flagellar protein FliS
OOOKNECK_01466 2.3e-239 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
OOOKNECK_01467 1.9e-101 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OOOKNECK_01468 2.3e-31 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OOOKNECK_01469 8.5e-75 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
OOOKNECK_01470 4.1e-77 yviE
OOOKNECK_01471 7.4e-161 flgL N Belongs to the bacterial flagellin family
OOOKNECK_01472 3.5e-272 flgK N flagellar hook-associated protein
OOOKNECK_01473 5.4e-78 flgN NOU FlgN protein
OOOKNECK_01474 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
OOOKNECK_01475 3.9e-72 yvyF S flagellar protein
OOOKNECK_01476 6.2e-62 comFC S Phosphoribosyl transferase domain
OOOKNECK_01477 8.2e-42 comFB S Late competence development protein ComFB
OOOKNECK_01478 2.9e-249 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
OOOKNECK_01479 8.1e-154 degV S protein conserved in bacteria
OOOKNECK_01480 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_01481 2.4e-180 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
OOOKNECK_01482 1e-116 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
OOOKNECK_01483 4.2e-170 yvhJ K Transcriptional regulator
OOOKNECK_01484 1.4e-182 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
OOOKNECK_01485 5.6e-225 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
OOOKNECK_01486 1.9e-141 tuaG GT2 M Glycosyltransferase like family 2
OOOKNECK_01487 1.6e-107 tuaF M protein involved in exopolysaccharide biosynthesis
OOOKNECK_01488 5.4e-251 tuaE M Teichuronic acid biosynthesis protein
OOOKNECK_01489 1.5e-242 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOOKNECK_01490 1.4e-212 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
OOOKNECK_01491 4.8e-255 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_01492 1.4e-116 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
OOOKNECK_01493 9.7e-211 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_01494 1.1e-303 lytB 3.5.1.28 D Stage II sporulation protein
OOOKNECK_01495 1e-29
OOOKNECK_01496 5.2e-138 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
OOOKNECK_01497 7e-185 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
OOOKNECK_01498 2.1e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
OOOKNECK_01499 1e-178 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
OOOKNECK_01500 3.4e-136 tagG GM Transport permease protein
OOOKNECK_01501 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OOOKNECK_01502 4.9e-258 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
OOOKNECK_01503 3.4e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
OOOKNECK_01504 1.4e-139 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
OOOKNECK_01505 7.6e-203 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
OOOKNECK_01506 1.5e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
OOOKNECK_01507 3.8e-184 pmi 5.3.1.8 G mannose-6-phosphate isomerase
OOOKNECK_01508 6e-136 gerBA EG Spore germination protein
OOOKNECK_01509 3e-79 gerBA EG Spore germination protein
OOOKNECK_01510 1.4e-190 gerBB E Spore germination protein
OOOKNECK_01511 6.3e-166 gerAC S Spore germination protein
OOOKNECK_01512 1.2e-241 GT2,GT4 J Glycosyl transferase family 2
OOOKNECK_01513 1.6e-239 ywtG EGP Major facilitator Superfamily
OOOKNECK_01514 1.1e-173 ywtF K Transcriptional regulator
OOOKNECK_01515 2e-152 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
OOOKNECK_01516 4.1e-29 yttA 2.7.13.3 S Pfam Transposase IS66
OOOKNECK_01517 8.6e-229 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OOOKNECK_01518 3.8e-20 ywtC
OOOKNECK_01519 1.2e-216 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
OOOKNECK_01520 2.3e-70 pgsC S biosynthesis protein
OOOKNECK_01521 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
OOOKNECK_01522 1.2e-184 gerKA EG Spore germination protein
OOOKNECK_01523 2.1e-178 gerKB E Spore germination protein
OOOKNECK_01524 3.1e-50 gerKC S Spore germination B3/ GerAC like, C-terminal
OOOKNECK_01525 4.4e-113 gerKC S Spore germination B3/ GerAC like, C-terminal
OOOKNECK_01526 3.1e-173 rbsR K transcriptional
OOOKNECK_01527 1.9e-153 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OOOKNECK_01528 9e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
OOOKNECK_01529 8.4e-271 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
OOOKNECK_01530 3.5e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
OOOKNECK_01531 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
OOOKNECK_01532 3.9e-85 batE T Sh3 type 3 domain protein
OOOKNECK_01533 6.4e-88 ywrO 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
OOOKNECK_01534 9e-144 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
OOOKNECK_01535 9.6e-303 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
OOOKNECK_01536 7.1e-164 alsR K LysR substrate binding domain
OOOKNECK_01537 1.8e-232 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OOOKNECK_01538 1.2e-115 ywrJ
OOOKNECK_01539 1.5e-113 cotB
OOOKNECK_01540 8.5e-204 cotH M Spore Coat
OOOKNECK_01541 9.5e-07
OOOKNECK_01542 6.2e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
OOOKNECK_01544 1.3e-285 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
OOOKNECK_01545 3e-81 ywrC K Transcriptional regulator
OOOKNECK_01546 2e-98 ywrB P Chromate transporter
OOOKNECK_01547 5.4e-87 ywrA P COG2059 Chromate transport protein ChrA
OOOKNECK_01548 3.3e-102
OOOKNECK_01549 4.9e-63
OOOKNECK_01550 1.3e-73 S SMI1 / KNR4 family
OOOKNECK_01551 3.6e-18
OOOKNECK_01552 8.4e-59 S SUKH-4 immunity protein
OOOKNECK_01553 2.2e-231 ywqJ S Pre-toxin TG
OOOKNECK_01554 1e-27 ywqI S Family of unknown function (DUF5344)
OOOKNECK_01555 2.2e-17 S Domain of unknown function (DUF5082)
OOOKNECK_01556 3.5e-143 ywqG S Domain of unknown function (DUF1963)
OOOKNECK_01557 8e-241 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
OOOKNECK_01558 3.4e-135 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
OOOKNECK_01559 8.5e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
OOOKNECK_01560 2.1e-105 ywqC M biosynthesis protein
OOOKNECK_01561 2.6e-15
OOOKNECK_01562 4.2e-300 ywqB S SWIM zinc finger
OOOKNECK_01563 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OOOKNECK_01564 1.9e-150 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
OOOKNECK_01565 5.4e-136 glcR K DeoR C terminal sensor domain
OOOKNECK_01566 5.4e-56 ssbB L Single-stranded DNA-binding protein
OOOKNECK_01567 2.5e-56 ywpG
OOOKNECK_01568 9.9e-68 ywpF S YwpF-like protein
OOOKNECK_01569 5.9e-46 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
OOOKNECK_01570 4.9e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
OOOKNECK_01571 9.5e-192 S aspartate phosphatase
OOOKNECK_01572 1.5e-136 flhP N flagellar basal body
OOOKNECK_01573 8e-127 flhO N flagellar basal body
OOOKNECK_01574 2.7e-180 mbl D Rod shape-determining protein
OOOKNECK_01575 1.8e-44 spoIIID K Stage III sporulation protein D
OOOKNECK_01576 1.1e-71 ywoH K transcriptional
OOOKNECK_01577 4.1e-212 ywoG EGP Major facilitator Superfamily
OOOKNECK_01578 2.4e-270 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
OOOKNECK_01579 9.8e-242 ywoD EGP Major facilitator superfamily
OOOKNECK_01580 8.5e-99 phzA Q Isochorismatase family
OOOKNECK_01581 3.9e-226 amt P Ammonium transporter
OOOKNECK_01582 1.7e-57 nrgB K Belongs to the P(II) protein family
OOOKNECK_01583 1.1e-206 ftsW D Belongs to the SEDS family
OOOKNECK_01584 1.3e-99 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
OOOKNECK_01585 6.4e-67 ywnJ S VanZ like family
OOOKNECK_01586 1.6e-120 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
OOOKNECK_01587 3.9e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
OOOKNECK_01588 3.1e-11 ywnC S Family of unknown function (DUF5362)
OOOKNECK_01589 1.3e-67 ywnF S Family of unknown function (DUF5392)
OOOKNECK_01590 1.2e-274 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OOOKNECK_01591 8.6e-16 yqgA
OOOKNECK_01592 1.3e-50 ywnC S Family of unknown function (DUF5362)
OOOKNECK_01593 3.7e-90 ywnB S NAD(P)H-binding
OOOKNECK_01594 6.1e-67 ywnA K Transcriptional regulator
OOOKNECK_01595 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
OOOKNECK_01596 5.5e-62 ureB 3.5.1.5 E Belongs to the urease beta subunit family
OOOKNECK_01597 2e-49 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
OOOKNECK_01598 1.2e-09 csbD K CsbD-like
OOOKNECK_01599 1.2e-80 ywmF S Peptidase M50
OOOKNECK_01600 8.2e-93 S response regulator aspartate phosphatase
OOOKNECK_01601 3.8e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OOOKNECK_01602 1e-142 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OOOKNECK_01604 8.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
OOOKNECK_01605 1.3e-112 ywmC S protein containing a von Willebrand factor type A (vWA) domain
OOOKNECK_01606 1.2e-180 spoIID D Stage II sporulation protein D
OOOKNECK_01607 8.2e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOOKNECK_01608 1.7e-131 ywmB S TATA-box binding
OOOKNECK_01609 6.2e-32 ywzB S membrane
OOOKNECK_01610 4.3e-88 ywmA
OOOKNECK_01611 5.3e-63 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
OOOKNECK_01612 1e-265 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OOOKNECK_01613 5.9e-152 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OOOKNECK_01614 8.2e-282 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OOOKNECK_01615 4.5e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OOOKNECK_01616 3e-42 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OOOKNECK_01617 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OOOKNECK_01618 5.4e-130 atpB C it plays a direct role in the translocation of protons across the membrane
OOOKNECK_01619 2.8e-61 atpI S ATP synthase
OOOKNECK_01620 4e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OOOKNECK_01621 9.6e-236 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OOOKNECK_01622 2.7e-94 ywlG S Belongs to the UPF0340 family
OOOKNECK_01623 4.6e-79 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
OOOKNECK_01624 1.1e-72 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OOOKNECK_01625 6.2e-86 mntP P Probably functions as a manganese efflux pump
OOOKNECK_01626 3.7e-155 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
OOOKNECK_01627 3.7e-73 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
OOOKNECK_01628 9.2e-116 spoIIR S stage II sporulation protein R
OOOKNECK_01629 9.7e-59 ywlA S Uncharacterised protein family (UPF0715)
OOOKNECK_01631 5.9e-152 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
OOOKNECK_01632 2.6e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OOOKNECK_01633 2.4e-65 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_01634 2.7e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
OOOKNECK_01635 1.1e-151 ywkB S Membrane transport protein
OOOKNECK_01636 0.0 sfcA 1.1.1.38 C malic enzyme
OOOKNECK_01637 5.6e-101 tdk 2.7.1.21 F thymidine kinase
OOOKNECK_01638 1.1e-32 rpmE J Binds the 23S rRNA
OOOKNECK_01639 4.3e-239 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OOOKNECK_01640 1.1e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
OOOKNECK_01641 3.5e-97 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOOKNECK_01642 2.5e-133 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OOOKNECK_01643 7.1e-110 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OOOKNECK_01644 2.7e-157 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
OOOKNECK_01645 8.5e-63 spo0F T COG0784 FOG CheY-like receiver
OOOKNECK_01646 1.8e-90 ywjG S Domain of unknown function (DUF2529)
OOOKNECK_01647 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
OOOKNECK_01648 7.1e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
OOOKNECK_01649 0.0 fadF C COG0247 Fe-S oxidoreductase
OOOKNECK_01650 1.1e-201 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
OOOKNECK_01651 2.1e-174 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
OOOKNECK_01652 9.3e-43 ywjC
OOOKNECK_01653 0.0 ywjA V ABC transporter
OOOKNECK_01654 8.5e-290 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OOOKNECK_01655 1.4e-116 narI 1.7.5.1 C nitrate reductase, gamma
OOOKNECK_01656 4e-85 narJ 1.7.5.1 C nitrate reductase
OOOKNECK_01657 3.8e-292 narH 1.7.5.1 C Nitrate reductase, beta
OOOKNECK_01658 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOOKNECK_01659 2.7e-205 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOOKNECK_01660 1.4e-78 arfM T cyclic nucleotide binding
OOOKNECK_01661 1.6e-126 ywiC S YwiC-like protein
OOOKNECK_01662 1.4e-125 fnr K helix_turn_helix, cAMP Regulatory protein
OOOKNECK_01663 4.3e-209 narK P COG2223 Nitrate nitrite transporter
OOOKNECK_01664 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
OOOKNECK_01665 1.5e-71 ywiB S protein conserved in bacteria
OOOKNECK_01667 1.2e-189 ywhL CO amine dehydrogenase activity
OOOKNECK_01668 5.8e-78 S aspartate phosphatase
OOOKNECK_01670 2.3e-167 speB 3.5.3.11 E Belongs to the arginase family
OOOKNECK_01671 1.6e-157 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OOOKNECK_01672 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOOKNECK_01673 3e-72
OOOKNECK_01674 5.1e-90 ywhD S YwhD family
OOOKNECK_01675 2.1e-117 ywhC S Peptidase family M50
OOOKNECK_01676 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
OOOKNECK_01677 9.8e-68 ywhA K Transcriptional regulator
OOOKNECK_01678 4.9e-241 yhdG_1 E C-terminus of AA_permease
OOOKNECK_01679 1.7e-87 ywgA 2.1.1.72, 3.1.21.3
OOOKNECK_01680 1.5e-252 ywfO S COG1078 HD superfamily phosphohydrolases
OOOKNECK_01681 6.9e-36 ywzC S Belongs to the UPF0741 family
OOOKNECK_01682 2.2e-105 rsfA_1
OOOKNECK_01684 1.3e-48 padR K PadR family transcriptional regulator
OOOKNECK_01685 9e-85 S membrane
OOOKNECK_01686 1.1e-92 V ABC transporter, ATP-binding protein
OOOKNECK_01687 1.1e-42 V ABC transporter, ATP-binding protein
OOOKNECK_01688 2.4e-162 yhcI S ABC transporter (permease)
OOOKNECK_01691 1.9e-164
OOOKNECK_01693 2.2e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
OOOKNECK_01694 1e-154 cysL K Transcriptional regulator
OOOKNECK_01695 1.5e-151 MA20_14895 S Conserved hypothetical protein 698
OOOKNECK_01696 8.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
OOOKNECK_01697 9e-144 ywfI C May function as heme-dependent peroxidase
OOOKNECK_01698 8.9e-139 IQ Enoyl-(Acyl carrier protein) reductase
OOOKNECK_01699 4.9e-229 ywfG 2.6.1.83 E Aminotransferase class I and II
OOOKNECK_01700 4.7e-208 bacE EGP Major facilitator Superfamily
OOOKNECK_01701 8e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
OOOKNECK_01702 3.3e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_01703 1.1e-135 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
OOOKNECK_01704 1.4e-110 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
OOOKNECK_01705 5.8e-217 ywfA EGP Major facilitator Superfamily
OOOKNECK_01706 8.8e-170 tcaB EGP Major facilitator Superfamily
OOOKNECK_01707 4.2e-256 lysP E amino acid
OOOKNECK_01708 0.0 rocB E arginine degradation protein
OOOKNECK_01709 2.1e-293 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OOOKNECK_01710 1.1e-245 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOOKNECK_01711 2.6e-61
OOOKNECK_01712 1.3e-84 spsL 5.1.3.13 M Spore Coat
OOOKNECK_01713 5.6e-155 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
OOOKNECK_01714 1e-176 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
OOOKNECK_01715 4.5e-132 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OOOKNECK_01716 5.8e-167 spsG M Spore Coat
OOOKNECK_01717 2.6e-124 spsF M Spore Coat
OOOKNECK_01718 1.4e-209 spsE 2.5.1.56 M acid synthase
OOOKNECK_01719 4.4e-118 spsD 2.3.1.210 K Spore Coat
OOOKNECK_01720 1e-215 spsC E Belongs to the DegT DnrJ EryC1 family
OOOKNECK_01721 2.7e-258 spsB M Capsule polysaccharide biosynthesis protein
OOOKNECK_01722 9.4e-141 spsA M Spore Coat
OOOKNECK_01723 1.6e-62 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
OOOKNECK_01724 5e-55 ywdK S small membrane protein
OOOKNECK_01725 1.9e-226 ywdJ F Xanthine uracil
OOOKNECK_01726 5.4e-36 ywdI S Family of unknown function (DUF5327)
OOOKNECK_01727 5.4e-132 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OOOKNECK_01728 9.2e-147 ywdF GT2,GT4 S Glycosyltransferase like family 2
OOOKNECK_01730 1.9e-144 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
OOOKNECK_01731 1.5e-20 ywdA
OOOKNECK_01732 5.8e-269 scrB 3.2.1.26, 3.2.1.65 GH32 G invertase
OOOKNECK_01733 2.1e-247 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_01734 7e-150 sacT K transcriptional antiterminator
OOOKNECK_01736 0.0 vpr O Belongs to the peptidase S8 family
OOOKNECK_01737 6.4e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_01738 2.7e-118 M1-869 K WYL domain
OOOKNECK_01739 4e-126 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_01740 3.2e-42 S Ketosteroid isomerase-related protein
OOOKNECK_01741 2.1e-32 S Stress responsive A/B Barrel Domain
OOOKNECK_01742 6.8e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
OOOKNECK_01743 1.8e-207 rodA D Belongs to the SEDS family
OOOKNECK_01744 6.3e-68 ysnE K acetyltransferase
OOOKNECK_01745 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
OOOKNECK_01746 1.6e-61 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OOOKNECK_01747 2.3e-110 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
OOOKNECK_01748 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OOOKNECK_01749 1.6e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
OOOKNECK_01750 8.4e-27 ywzA S membrane
OOOKNECK_01751 6.4e-282 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
OOOKNECK_01752 2.1e-208 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OOOKNECK_01753 9.6e-60 gtcA S GtrA-like protein
OOOKNECK_01754 1.1e-96 ywcC K Bacterial regulatory proteins, tetR family
OOOKNECK_01756 8.3e-125 H Methionine biosynthesis protein MetW
OOOKNECK_01757 6.8e-119 S Streptomycin biosynthesis protein StrF
OOOKNECK_01758 6.3e-108 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
OOOKNECK_01759 1e-232 ywbN P Dyp-type peroxidase family protein
OOOKNECK_01760 2.4e-132 ycdO P periplasmic lipoprotein involved in iron transport
OOOKNECK_01761 3.6e-194 P COG0672 High-affinity Fe2 Pb2 permease
OOOKNECK_01762 1.8e-108 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
OOOKNECK_01763 4.8e-127 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
OOOKNECK_01764 2.6e-150 ywbI K Transcriptional regulator
OOOKNECK_01765 2.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
OOOKNECK_01766 2.2e-109 ywbG M effector of murein hydrolase
OOOKNECK_01767 1.5e-26 ywbE S Uncharacterized conserved protein (DUF2196)
OOOKNECK_01768 1.8e-128 mta K transcriptional
OOOKNECK_01769 7.1e-156 yjfC O Predicted Zn-dependent protease (DUF2268)
OOOKNECK_01770 4.9e-221 ywbD 2.1.1.191 J Methyltransferase
OOOKNECK_01771 2.9e-66 ywbC 4.4.1.5 E glyoxalase
OOOKNECK_01772 1.6e-241 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOOKNECK_01773 4.6e-234 epr 3.4.21.62 O Belongs to the peptidase S8 family
OOOKNECK_01774 1.6e-160 gspA M General stress
OOOKNECK_01776 2.9e-116 ywaC 2.7.6.5 S protein conserved in bacteria
OOOKNECK_01777 1.9e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
OOOKNECK_01778 4.7e-12 S D-Ala-teichoic acid biosynthesis protein
OOOKNECK_01779 7.7e-288 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_01780 6.5e-226 dltB M membrane protein involved in D-alanine export
OOOKNECK_01781 5.6e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_01782 5.6e-193 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
OOOKNECK_01783 5.5e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OOOKNECK_01784 2.3e-248 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OOOKNECK_01785 6.2e-49 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOOKNECK_01786 1.2e-244 licC 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOOKNECK_01787 7.5e-49 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
OOOKNECK_01788 2.6e-228 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OOOKNECK_01789 1e-117 licR 2.7.1.202 GKT Mga helix-turn-helix domain
OOOKNECK_01790 5.2e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
OOOKNECK_01791 2.9e-169 fhuB3 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_01792 3.3e-178 fhuG1 P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_01793 2.2e-165 cbrA3 P Periplasmic binding protein
OOOKNECK_01794 1.2e-50 arsR K transcriptional
OOOKNECK_01795 3.9e-224 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OOOKNECK_01796 4.9e-48 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOOKNECK_01797 1.9e-47 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
OOOKNECK_01798 1.8e-224 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
OOOKNECK_01799 1.8e-278 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOOKNECK_01800 1.1e-161 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
OOOKNECK_01801 3.1e-178 manA 5.3.1.8 G mannose-6-phosphate isomerase
OOOKNECK_01802 6.9e-206 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
OOOKNECK_01803 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
OOOKNECK_01804 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
OOOKNECK_01805 6.3e-249 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
OOOKNECK_01806 2e-149 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OOOKNECK_01807 7.4e-287 cydD V ATP-binding protein
OOOKNECK_01808 6.4e-307 cydD V ATP-binding
OOOKNECK_01809 5.7e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
OOOKNECK_01810 3.8e-265 cydA 1.10.3.14 C oxidase, subunit
OOOKNECK_01811 2.3e-211 cimH C COG3493 Na citrate symporter
OOOKNECK_01812 1.2e-149 yxkH G Polysaccharide deacetylase
OOOKNECK_01813 6.5e-204 msmK P Belongs to the ABC transporter superfamily
OOOKNECK_01814 2e-155 lrp QT PucR C-terminal helix-turn-helix domain
OOOKNECK_01815 6.4e-143 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
OOOKNECK_01817 3.7e-82 yxkC S Domain of unknown function (DUF4352)
OOOKNECK_01818 2.6e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
OOOKNECK_01819 2.6e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
OOOKNECK_01822 3e-81 yxjI S LURP-one-related
OOOKNECK_01823 9.4e-214 yxjG 2.1.1.14 E Methionine synthase
OOOKNECK_01824 1.8e-143 rlmA 2.1.1.187 Q Methyltransferase domain
OOOKNECK_01825 6.8e-208 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOOKNECK_01826 6e-67 T Domain of unknown function (DUF4163)
OOOKNECK_01827 2.8e-45 yxiS
OOOKNECK_01828 6.4e-181 L DNA synthesis involved in DNA repair
OOOKNECK_01829 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
OOOKNECK_01830 6.8e-221 citH C Citrate transporter
OOOKNECK_01831 3.8e-136 exoK GH16 M licheninase activity
OOOKNECK_01832 1.8e-142 licT K transcriptional antiterminator
OOOKNECK_01833 1.6e-219 yxiO S COG2270 Permeases of the major facilitator superfamily
OOOKNECK_01834 3.4e-253 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
OOOKNECK_01836 1.4e-21
OOOKNECK_01837 5.8e-14 S YxiJ-like protein
OOOKNECK_01838 3.9e-111
OOOKNECK_01839 5.6e-77
OOOKNECK_01840 9.9e-65 yxiG
OOOKNECK_01841 2.6e-57 yxxG
OOOKNECK_01843 1.3e-196 pelB 4.2.2.10, 4.2.2.2 G Pectate lyase
OOOKNECK_01844 1.5e-142 yxxF EG EamA-like transporter family
OOOKNECK_01845 4.1e-72 yxiE T Belongs to the universal stress protein A family
OOOKNECK_01846 3.1e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOOKNECK_01847 6.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_01848 1.7e-46 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
OOOKNECK_01849 2e-146 dcm 2.1.1.37 L C-5 cytosine-specific DNA methylase
OOOKNECK_01850 1.5e-63 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
OOOKNECK_01851 2.9e-76 L Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
OOOKNECK_01852 2e-262 L Z1 domain
OOOKNECK_01853 3.4e-82 S Putative PD-(D/E)XK family member, (DUF4420)
OOOKNECK_01854 3.3e-197 S AIPR protein
OOOKNECK_01855 2e-266 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OOOKNECK_01856 8.5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
OOOKNECK_01857 1.1e-281 hutH 4.3.1.3 E Histidine ammonia-lyase
OOOKNECK_01858 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OOOKNECK_01859 9.4e-231 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
OOOKNECK_01860 1e-168 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
OOOKNECK_01861 5e-249 lysP E amino acid
OOOKNECK_01862 3.3e-231 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
OOOKNECK_01863 1.2e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OOOKNECK_01864 9.4e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OOOKNECK_01865 5.3e-170 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
OOOKNECK_01866 2.1e-146 yidA S hydrolases of the HAD superfamily
OOOKNECK_01871 7.9e-21 yxeD
OOOKNECK_01872 2.7e-35
OOOKNECK_01873 1.2e-169 fhuD P Periplasmic binding protein
OOOKNECK_01874 2.7e-55 yxeA S Protein of unknown function (DUF1093)
OOOKNECK_01875 0.0 yxdM V ABC transporter (permease)
OOOKNECK_01876 1.4e-136 yxdL V ABC transporter, ATP-binding protein
OOOKNECK_01877 9.6e-175 T PhoQ Sensor
OOOKNECK_01878 1.9e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_01879 4.6e-152 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
OOOKNECK_01880 4.8e-146 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
OOOKNECK_01881 6.8e-164 iolH G Xylose isomerase-like TIM barrel
OOOKNECK_01882 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
OOOKNECK_01883 2e-228 iolF EGP Major facilitator Superfamily
OOOKNECK_01884 1.8e-172 iolE 4.2.1.44 H Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
OOOKNECK_01885 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
OOOKNECK_01886 1.6e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
OOOKNECK_01887 8.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
OOOKNECK_01888 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOOKNECK_01889 8.9e-136 iolR K COG1349 Transcriptional regulators of sugar metabolism
OOOKNECK_01890 6.2e-171 iolS C Aldo keto reductase
OOOKNECK_01891 4.8e-244 csbC EGP Major facilitator Superfamily
OOOKNECK_01892 0.0 htpG O Molecular chaperone. Has ATPase activity
OOOKNECK_01893 2.1e-146 IQ Enoyl-(Acyl carrier protein) reductase
OOOKNECK_01894 1.6e-100 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
OOOKNECK_01895 3.5e-192 desK 2.7.13.3 T Histidine kinase
OOOKNECK_01896 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
OOOKNECK_01897 1.4e-209 yxbF K Bacterial regulatory proteins, tetR family
OOOKNECK_01898 4.9e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
OOOKNECK_01899 1.6e-137 S PQQ-like domain
OOOKNECK_01900 2.7e-57 S Family of unknown function (DUF5391)
OOOKNECK_01901 4.3e-49 arsR3 K helix_turn_helix, Arsenical Resistance Operon Repressor
OOOKNECK_01902 5.1e-199 EGP Major facilitator Superfamily
OOOKNECK_01903 1.9e-64 yxaI S membrane protein domain
OOOKNECK_01904 9e-119 E Ring-cleavage extradiol dioxygenase
OOOKNECK_01905 9.4e-106 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
OOOKNECK_01906 8.9e-284 ahpF O Alkyl hydroperoxide reductase
OOOKNECK_01907 9e-186 G Major royal jelly protein
OOOKNECK_01908 1e-235 aapA E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_01909 3.4e-156 K helix_turn_helix, Deoxyribose operon repressor
OOOKNECK_01910 1.4e-73 K Integron-associated effector binding protein
OOOKNECK_01911 5.4e-75 yjhE S Phage tail protein
OOOKNECK_01912 6.2e-55 yqaS L DNA packaging
OOOKNECK_01913 3.8e-181 ps334 S Terminase-like family
OOOKNECK_01914 6e-157 S Phage portal protein, SPP1 Gp6-like
OOOKNECK_01916 1.4e-50 S Domain of unknown function (DUF4355)
OOOKNECK_01917 7.1e-121 S P22 coat protein - gene protein 5
OOOKNECK_01919 3.9e-34 S Phage Mu protein F like protein
OOOKNECK_01920 4.8e-17 S Phage gp6-like head-tail connector protein
OOOKNECK_01921 1e-47
OOOKNECK_01922 1.1e-25
OOOKNECK_01923 1.3e-31
OOOKNECK_01924 8e-103 Z012_02110 S Protein of unknown function (DUF3383)
OOOKNECK_01925 1.4e-34
OOOKNECK_01926 2.4e-15
OOOKNECK_01927 4.2e-127 N phage tail tape measure protein
OOOKNECK_01928 2.1e-41 3.5.1.28 M LysM domain
OOOKNECK_01929 2e-29
OOOKNECK_01930 8.9e-88
OOOKNECK_01931 4.5e-26
OOOKNECK_01932 3e-25 S Protein of unknown function (DUF2634)
OOOKNECK_01933 3.4e-102 Z012_12235 S homolog of phage Mu protein gp47
OOOKNECK_01934 1.7e-60
OOOKNECK_01935 5.2e-48
OOOKNECK_01937 1.5e-18 xkdX
OOOKNECK_01938 2.1e-29 xhlA S Haemolysin XhlA
OOOKNECK_01939 3.7e-28 xhlB S SPP1 phage holin
OOOKNECK_01940 1.9e-73 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_01942 1.2e-27 K Helix-turn-helix domain
OOOKNECK_01943 4.4e-89 T Histidine kinase-like ATPases
OOOKNECK_01944 1.2e-22 S STAS-like domain of unknown function (DUF4325)
OOOKNECK_01945 3.1e-13
OOOKNECK_01946 4.8e-08
OOOKNECK_01947 3.7e-10 lexA 3.4.21.88 KT domain protein
OOOKNECK_01948 2.7e-155 L Recombinase
OOOKNECK_01949 4.1e-72 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_01950 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
OOOKNECK_01951 3.4e-197 gerM S COG5401 Spore germination protein
OOOKNECK_01952 5.8e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OOOKNECK_01953 8e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OOOKNECK_01954 6.1e-88 ysnB S Phosphoesterase
OOOKNECK_01959 1.4e-87 ilvB 2.2.1.6 E Acetolactate synthase
OOOKNECK_01960 6.4e-185 ilvB 2.2.1.6 E Acetolactate synthase
OOOKNECK_01961 3.5e-83 ilvN 2.2.1.6 E Acetolactate synthase
OOOKNECK_01962 2.4e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OOOKNECK_01963 9e-284 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OOOKNECK_01964 6.5e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
OOOKNECK_01965 2.5e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OOOKNECK_01966 1.3e-113 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OOOKNECK_01967 1e-187 ysoA H Tetratricopeptide repeat
OOOKNECK_01968 7.5e-212 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
OOOKNECK_01969 3.8e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OOOKNECK_01970 7.5e-245 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OOOKNECK_01971 6.4e-38 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
OOOKNECK_01972 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OOOKNECK_01973 1.5e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
OOOKNECK_01974 5.1e-84 ysxD
OOOKNECK_01975 2.1e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OOOKNECK_01976 3.6e-146 hemX O cytochrome C
OOOKNECK_01977 1.8e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
OOOKNECK_01978 1.1e-136 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
OOOKNECK_01979 2.5e-183 hemB 4.2.1.24 H Belongs to the ALAD family
OOOKNECK_01980 7.1e-242 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OOOKNECK_01981 5.7e-150 spoVID M stage VI sporulation protein D
OOOKNECK_01982 4.9e-185 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OOOKNECK_01983 3.1e-24
OOOKNECK_01984 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
OOOKNECK_01985 1.2e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
OOOKNECK_01986 2.7e-86 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
OOOKNECK_01987 2.5e-125 spoIIB S Sporulation related domain
OOOKNECK_01988 3.8e-99 maf D septum formation protein Maf
OOOKNECK_01989 4.5e-126 radC E Belongs to the UPF0758 family
OOOKNECK_01990 1.3e-182 mreB D Rod shape-determining protein MreB
OOOKNECK_01991 8e-157 mreC M Involved in formation and maintenance of cell shape
OOOKNECK_01992 1.1e-81 mreD M shape-determining protein
OOOKNECK_01993 2.2e-101 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
OOOKNECK_01994 2.3e-142 minD D Belongs to the ParA family
OOOKNECK_01995 3.8e-137 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
OOOKNECK_01996 2.3e-156 spoIVFB S Stage IV sporulation protein
OOOKNECK_01997 9.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
OOOKNECK_01998 7e-56 ysxB J ribosomal protein
OOOKNECK_01999 5.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
OOOKNECK_02000 4.8e-105 spo0B T Sporulation initiation phospho-transferase B, C-terminal
OOOKNECK_02001 6.4e-235 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OOOKNECK_02002 4.8e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
OOOKNECK_02003 6.1e-157 pheA 4.2.1.51 E Prephenate dehydratase
OOOKNECK_02004 2.9e-88 niaR S small molecule binding protein (contains 3H domain)
OOOKNECK_02005 3.4e-211 nifS 2.8.1.7 E Cysteine desulfurase
OOOKNECK_02006 4.8e-277 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
OOOKNECK_02007 3.2e-142 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
OOOKNECK_02008 3.4e-208 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OOOKNECK_02009 7.8e-99 safA M spore coat assembly protein SafA
OOOKNECK_02010 6.1e-47 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOOKNECK_02012 5e-90 bofC S BofC C-terminal domain
OOOKNECK_02013 5.9e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
OOOKNECK_02014 2.9e-182 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
OOOKNECK_02015 2.8e-20 yrzS S Protein of unknown function (DUF2905)
OOOKNECK_02016 2.7e-191 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OOOKNECK_02017 5.1e-130 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OOOKNECK_02018 7.4e-85 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
OOOKNECK_02019 2.5e-37 yajC U Preprotein translocase subunit YajC
OOOKNECK_02020 5.3e-60 yrzE S Protein of unknown function (DUF3792)
OOOKNECK_02021 5.1e-103 yrbG S membrane
OOOKNECK_02022 1.2e-267 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_02023 8e-48 yrzD S Post-transcriptional regulator
OOOKNECK_02024 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OOOKNECK_02025 4.6e-80 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
OOOKNECK_02026 2.7e-44 yrvD S Lipopolysaccharide assembly protein A domain
OOOKNECK_02027 3e-176 recJ L DHH family
OOOKNECK_02028 2.7e-215 recJ L Single-stranded-DNA-specific exonuclease RecJ
OOOKNECK_02029 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OOOKNECK_02030 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OOOKNECK_02031 1.1e-74 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
OOOKNECK_02032 1e-266 lytH 3.5.1.28 M COG3103 SH3 domain protein
OOOKNECK_02035 4.5e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
OOOKNECK_02036 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OOOKNECK_02037 3.3e-138 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
OOOKNECK_02038 7e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
OOOKNECK_02039 2.9e-63 cymR K Transcriptional regulator
OOOKNECK_02040 7e-209 iscS 2.8.1.7 E Cysteine desulfurase
OOOKNECK_02041 5e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
OOOKNECK_02042 1.7e-18 S COG0457 FOG TPR repeat
OOOKNECK_02043 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
OOOKNECK_02044 1.1e-77 yrrD S protein conserved in bacteria
OOOKNECK_02045 2.9e-30 yrzR
OOOKNECK_02046 2.1e-08 S Protein of unknown function (DUF3918)
OOOKNECK_02047 6e-104 glnP P ABC transporter
OOOKNECK_02048 6.8e-108 gluC P ABC transporter
OOOKNECK_02049 9.7e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
OOOKNECK_02050 1.6e-126 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOOKNECK_02051 2.2e-156 yrrI S AI-2E family transporter
OOOKNECK_02052 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OOOKNECK_02053 8.5e-41 yrzL S Belongs to the UPF0297 family
OOOKNECK_02054 3.6e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OOOKNECK_02055 7.1e-46 yrzB S Belongs to the UPF0473 family
OOOKNECK_02056 7.7e-181 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OOOKNECK_02057 1.6e-112 yrrM 2.1.1.104 S O-methyltransferase
OOOKNECK_02058 2.8e-171 yegQ O Peptidase U32
OOOKNECK_02059 5.1e-245 yegQ O COG0826 Collagenase and related proteases
OOOKNECK_02060 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
OOOKNECK_02061 5.9e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
OOOKNECK_02062 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
OOOKNECK_02063 1.2e-65 yrrS S Protein of unknown function (DUF1510)
OOOKNECK_02064 5.3e-27 yrzA S Protein of unknown function (DUF2536)
OOOKNECK_02065 3.7e-114 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
OOOKNECK_02066 4.7e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OOOKNECK_02067 7.8e-166 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
OOOKNECK_02068 3.7e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
OOOKNECK_02069 1e-34 yrhC S YrhC-like protein
OOOKNECK_02070 3.2e-78 yrhD S Protein of unknown function (DUF1641)
OOOKNECK_02071 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase, alpha subunit
OOOKNECK_02072 1e-60 yrhF S Uncharacterized conserved protein (DUF2294)
OOOKNECK_02073 1.4e-139 focA P Formate nitrite
OOOKNECK_02075 1.6e-86 yrhH Q methyltransferase
OOOKNECK_02076 8.8e-96 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
OOOKNECK_02077 0.0 MA20_16700 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OOOKNECK_02078 1.2e-206 ynfM EGP Major facilitator Superfamily
OOOKNECK_02079 2.8e-160 yybE K Transcriptional regulator
OOOKNECK_02080 1.8e-73 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OOOKNECK_02081 1.4e-167 romA S Beta-lactamase superfamily domain
OOOKNECK_02082 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
OOOKNECK_02083 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
OOOKNECK_02084 1.3e-171 manA 5.3.1.8 G mannose-6-phosphate isomerase
OOOKNECK_02085 5.1e-117 glvR K Helix-turn-helix domain, rpiR family
OOOKNECK_02086 1.6e-138 ybjI 3.1.3.102, 3.1.3.104, 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
OOOKNECK_02087 7e-139 S hydrolase
OOOKNECK_02088 1.9e-86 yrdA S DinB family
OOOKNECK_02089 9.6e-221 tetL EGP Major facilitator Superfamily
OOOKNECK_02090 2e-26 yyaR K acetyltransferase
OOOKNECK_02091 8.9e-98 adk 2.7.4.3 F adenylate kinase activity
OOOKNECK_02092 4.6e-88 K Transcriptional regulator PadR-like family
OOOKNECK_02093 7.1e-158 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
OOOKNECK_02094 6.4e-123 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_02095 6.3e-187 EGP Major facilitator Superfamily
OOOKNECK_02096 1.3e-15 2.3.1.57 K Acetyltransferase (GNAT) domain
OOOKNECK_02097 7.5e-104 yqeD S SNARE associated Golgi protein
OOOKNECK_02098 4.6e-108 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_02099 1.4e-133 3.5.1.104 G Polysaccharide deacetylase
OOOKNECK_02100 8.6e-136 yqeF E GDSL-like Lipase/Acylhydrolase
OOOKNECK_02102 7.7e-94 yqeG S hydrolase of the HAD superfamily
OOOKNECK_02103 1.5e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
OOOKNECK_02104 1.4e-153 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OOOKNECK_02105 1.5e-43 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
OOOKNECK_02106 6.3e-102 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OOOKNECK_02107 6.2e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
OOOKNECK_02108 2.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
OOOKNECK_02109 8.7e-136 yqeM Q Methyltransferase
OOOKNECK_02110 8.2e-143 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOOKNECK_02111 3.1e-94 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
OOOKNECK_02112 8.9e-104 comEB 3.5.4.12 F ComE operon protein 2
OOOKNECK_02113 2.2e-297 comEC S Competence protein ComEC
OOOKNECK_02114 1.8e-90 comEC S Competence protein ComEC
OOOKNECK_02115 3.2e-15 S YqzM-like protein
OOOKNECK_02116 4.4e-178 holA 2.7.7.7 L DNA polymerase III delta subunit
OOOKNECK_02117 2.2e-36 rpsT J Binds directly to 16S ribosomal RNA
OOOKNECK_02118 5.6e-203 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OOOKNECK_02119 2e-219 spoIIP M stage II sporulation protein P
OOOKNECK_02120 2.7e-52 yqxA S Protein of unknown function (DUF3679)
OOOKNECK_02121 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
OOOKNECK_02122 6.3e-210 hemN H Involved in the biosynthesis of porphyrin-containing compound
OOOKNECK_02123 9.8e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
OOOKNECK_02124 2.1e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OOOKNECK_02125 0.0 dnaK O Heat shock 70 kDa protein
OOOKNECK_02126 1.2e-197 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
OOOKNECK_02127 6e-174 prmA J Methylates ribosomal protein L11
OOOKNECK_02128 6.3e-137 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
OOOKNECK_02129 4.3e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
OOOKNECK_02130 1.7e-152 yqeW P COG1283 Na phosphate symporter
OOOKNECK_02131 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
OOOKNECK_02132 1.2e-68 yqeY S Yqey-like protein
OOOKNECK_02133 4.7e-225 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
OOOKNECK_02134 5.3e-120 yqfA S UPF0365 protein
OOOKNECK_02135 2.2e-22 yqfB
OOOKNECK_02136 9.3e-46 yqfC S sporulation protein YqfC
OOOKNECK_02137 2.3e-207 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
OOOKNECK_02138 2.1e-174 phoH T Phosphate starvation-inducible protein PhoH
OOOKNECK_02139 0.0 yqfF S membrane-associated HD superfamily hydrolase
OOOKNECK_02140 9.7e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OOOKNECK_02141 8.6e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
OOOKNECK_02142 2.7e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
OOOKNECK_02143 4e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OOOKNECK_02144 1.8e-16 S YqzL-like protein
OOOKNECK_02145 6.1e-140 recO L Involved in DNA repair and RecF pathway recombination
OOOKNECK_02146 3.7e-173 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
OOOKNECK_02147 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
OOOKNECK_02148 1.3e-111 ccpN K CBS domain
OOOKNECK_02149 1.4e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
OOOKNECK_02150 8.7e-87 yaiI S Belongs to the UPF0178 family
OOOKNECK_02151 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
OOOKNECK_02152 3.1e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
OOOKNECK_02153 1.3e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
OOOKNECK_02154 1.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
OOOKNECK_02155 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OOOKNECK_02156 1.9e-175 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OOOKNECK_02157 1.6e-25 yqfQ S YqfQ-like protein
OOOKNECK_02158 5.7e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
OOOKNECK_02159 1.1e-161 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OOOKNECK_02160 2.7e-36 yqfT S Protein of unknown function (DUF2624)
OOOKNECK_02161 1.1e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_02162 2.4e-71 zur P Belongs to the Fur family
OOOKNECK_02163 6.7e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
OOOKNECK_02164 6.7e-52 yqfX S membrane
OOOKNECK_02165 5.9e-200 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
OOOKNECK_02166 4.2e-44 yqfZ M LysM domain
OOOKNECK_02167 5.3e-128 yqgB S Protein of unknown function (DUF1189)
OOOKNECK_02168 4.2e-70 yqgC S protein conserved in bacteria
OOOKNECK_02169 5.3e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
OOOKNECK_02170 1.6e-208 yqgE EGP Major facilitator superfamily
OOOKNECK_02171 0.0 pbpA 3.4.16.4 M penicillin-binding protein
OOOKNECK_02172 2.3e-154 pstS P Phosphate
OOOKNECK_02173 6.8e-154 pstC P probably responsible for the translocation of the substrate across the membrane
OOOKNECK_02174 8.5e-154 pstA P Phosphate transport system permease
OOOKNECK_02175 2.2e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OOOKNECK_02176 6.4e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
OOOKNECK_02177 1.3e-73 yqzC S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OOOKNECK_02178 1.2e-50 yqzD
OOOKNECK_02179 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OOOKNECK_02180 6e-89 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OOOKNECK_02181 4e-07 yqgO
OOOKNECK_02182 8.6e-222 nhaC C Na H antiporter
OOOKNECK_02183 1.6e-27 yqgQ S Protein conserved in bacteria
OOOKNECK_02184 1.8e-178 glcK 2.7.1.2 G Glucokinase
OOOKNECK_02185 5.3e-201 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
OOOKNECK_02186 2.3e-187 yqgU
OOOKNECK_02187 1.7e-48 yqgV S Thiamine-binding protein
OOOKNECK_02188 5.4e-20 yqgW S Protein of unknown function (DUF2759)
OOOKNECK_02189 3.6e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
OOOKNECK_02190 3.1e-37 yqgY S Protein of unknown function (DUF2626)
OOOKNECK_02191 1.9e-62 yqgZ 1.20.4.1 P Belongs to the ArsC family
OOOKNECK_02193 3e-137 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOOKNECK_02194 1.5e-231 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
OOOKNECK_02195 6.7e-181 corA P Mg2 transporter protein
OOOKNECK_02196 8.9e-198 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OOOKNECK_02197 4e-179 comGB NU COG1459 Type II secretory pathway, component PulF
OOOKNECK_02198 1.3e-48 comGC U Required for transformation and DNA binding
OOOKNECK_02199 6.4e-70 gspH NU Tfp pilus assembly protein FimT
OOOKNECK_02200 1.2e-20 comGE
OOOKNECK_02201 4.1e-21 comGF U Putative Competence protein ComGF
OOOKNECK_02202 5.4e-57 S ComG operon protein 7
OOOKNECK_02203 1.5e-25 yqzE S YqzE-like protein
OOOKNECK_02204 1.1e-53 yqzG S Protein of unknown function (DUF3889)
OOOKNECK_02205 3.6e-112 yqxM
OOOKNECK_02206 5.2e-67 sipW 3.4.21.89 U Signal peptidase
OOOKNECK_02207 1.5e-138 tasA S Cell division protein FtsN
OOOKNECK_02208 3.9e-54 sinR K transcriptional
OOOKNECK_02209 1.7e-21 sinI S Anti-repressor SinI
OOOKNECK_02210 3.3e-149 yqhG S Bacterial protein YqhG of unknown function
OOOKNECK_02211 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
OOOKNECK_02212 5.7e-200 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
OOOKNECK_02213 1.2e-247 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OOOKNECK_02214 3.6e-282 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OOOKNECK_02215 1e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
OOOKNECK_02216 2.3e-137 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
OOOKNECK_02217 4.7e-73 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
OOOKNECK_02218 5.1e-159 yqhO S esterase of the alpha-beta hydrolase superfamily
OOOKNECK_02219 1.2e-59 yqhP
OOOKNECK_02220 9.1e-170 yqhQ S Protein of unknown function (DUF1385)
OOOKNECK_02221 1.1e-84 yqhR S Conserved membrane protein YqhR
OOOKNECK_02222 5.9e-170 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
OOOKNECK_02223 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OOOKNECK_02224 6.7e-36 yqhV S Protein of unknown function (DUF2619)
OOOKNECK_02225 1.7e-165 spoIIIAA S stage III sporulation protein AA
OOOKNECK_02226 1e-82 spoIIIAB S Stage III sporulation protein
OOOKNECK_02227 7.6e-29 spoIIIAC S stage III sporulation protein AC
OOOKNECK_02228 3.3e-41 spoIIIAD S Stage III sporulation protein AD
OOOKNECK_02229 4.1e-199 spoIIIAE S stage III sporulation protein AE
OOOKNECK_02230 1e-100 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
OOOKNECK_02231 1.4e-114 spoIIIAG S stage III sporulation protein AG
OOOKNECK_02232 1.3e-58 spoIIIAH S SpoIIIAH-like protein
OOOKNECK_02233 4.9e-63 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
OOOKNECK_02234 8.4e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
OOOKNECK_02235 1.4e-66 yqhY S protein conserved in bacteria
OOOKNECK_02236 9.5e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OOOKNECK_02237 5.7e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OOOKNECK_02238 2.5e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OOOKNECK_02239 1.3e-38 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
OOOKNECK_02240 7e-156 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OOOKNECK_02241 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OOOKNECK_02242 9.9e-152 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
OOOKNECK_02243 4.3e-77 argR K Regulates arginine biosynthesis genes
OOOKNECK_02244 6.2e-310 recN L May be involved in recombinational repair of damaged DNA
OOOKNECK_02245 3.2e-234 rseP 3.4.21.116 M Stage IV sporulation protein B
OOOKNECK_02246 2.7e-143 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
OOOKNECK_02248 7e-204 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOOKNECK_02251 5.8e-208 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
OOOKNECK_02253 3.7e-111 K Protein of unknown function (DUF1232)
OOOKNECK_02254 2.3e-92 ytaF P Probably functions as a manganese efflux pump
OOOKNECK_02255 5.7e-17
OOOKNECK_02256 1.4e-97 amiC 3.5.1.28 M Cell wall hydrolase autolysin
OOOKNECK_02257 9.6e-127 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOOKNECK_02258 3.2e-209 mmgA 2.3.1.9 I Belongs to the thiolase family
OOOKNECK_02259 8.5e-143 hbdA 1.1.1.157 I Dehydrogenase
OOOKNECK_02260 5.3e-201 mmgC I acyl-CoA dehydrogenase
OOOKNECK_02261 3.5e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
OOOKNECK_02262 7.8e-266 prpD 4.2.1.79 S 2-methylcitrate dehydratase
OOOKNECK_02263 7.1e-156 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OOOKNECK_02264 2.7e-33 yqzF S Protein of unknown function (DUF2627)
OOOKNECK_02265 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
OOOKNECK_02266 1.3e-149 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
OOOKNECK_02267 2.6e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOOKNECK_02268 2e-205 buk 2.7.2.7 C Belongs to the acetokinase family
OOOKNECK_02269 5.7e-261 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOOKNECK_02270 7.8e-164 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOOKNECK_02271 6.7e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOOKNECK_02272 3.5e-193 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOOKNECK_02273 1.6e-168 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OOOKNECK_02274 1e-75 yqiW S Belongs to the UPF0403 family
OOOKNECK_02275 4.2e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
OOOKNECK_02276 1.1e-105 artQ E COG0765 ABC-type amino acid transport system, permease component
OOOKNECK_02277 5.2e-125 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOOKNECK_02278 7.7e-169 yqjA S Putative aromatic acid exporter C-terminal domain
OOOKNECK_02279 3.6e-91 yqjB S protein conserved in bacteria
OOOKNECK_02281 2e-71 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
OOOKNECK_02282 1.9e-264 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
OOOKNECK_02283 1.2e-200 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
OOOKNECK_02284 2.1e-146 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OOOKNECK_02285 7.4e-27 yqzJ
OOOKNECK_02286 9.4e-231 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOOKNECK_02287 1.3e-265 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
OOOKNECK_02288 7.7e-285 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OOOKNECK_02289 2.8e-168 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
OOOKNECK_02290 4e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
OOOKNECK_02291 4.5e-143 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
OOOKNECK_02292 8.2e-193 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
OOOKNECK_02293 1.6e-46 S GlpM protein
OOOKNECK_02294 1.8e-156 K LysR substrate binding domain
OOOKNECK_02295 7.9e-141 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OOOKNECK_02296 2.3e-168 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
OOOKNECK_02297 1.8e-136 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
OOOKNECK_02298 1.1e-242 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
OOOKNECK_02299 5e-176 coaA 2.7.1.33 F Pantothenic acid kinase
OOOKNECK_02301 1.8e-145 yueF S transporter activity
OOOKNECK_02303 9.3e-56 S YolD-like protein
OOOKNECK_02304 5.7e-233 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OOOKNECK_02305 2.8e-87 yqjY K acetyltransferase
OOOKNECK_02306 1.6e-166 yqkA K GrpB protein
OOOKNECK_02307 1.6e-58 yqkB S Belongs to the HesB IscA family
OOOKNECK_02308 3.2e-39 yqkC S Protein of unknown function (DUF2552)
OOOKNECK_02309 3.4e-166 yqkD S COG1073 Hydrolases of the alpha beta superfamily
OOOKNECK_02311 1.2e-163 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
OOOKNECK_02313 9e-93 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
OOOKNECK_02314 2.5e-214 yqxK 3.6.4.12 L DNA helicase
OOOKNECK_02315 5e-57 ansR K Transcriptional regulator
OOOKNECK_02316 1.2e-183 ansA 3.5.1.1 EJ L-asparaginase
OOOKNECK_02317 1.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
OOOKNECK_02318 1.9e-240 mleN C Na H antiporter
OOOKNECK_02319 3.6e-241 mleA 1.1.1.38 C malic enzyme
OOOKNECK_02320 3e-23
OOOKNECK_02321 8.1e-32 yqkK
OOOKNECK_02322 2.7e-109 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
OOOKNECK_02323 2.7e-79 fur P Belongs to the Fur family
OOOKNECK_02324 6.4e-37 S Protein of unknown function (DUF4227)
OOOKNECK_02325 2.7e-163 xerD L recombinase XerD
OOOKNECK_02326 3.1e-228 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
OOOKNECK_02327 4.2e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OOOKNECK_02328 5.9e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
OOOKNECK_02329 2.3e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
OOOKNECK_02330 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
OOOKNECK_02331 6.9e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_02332 2.1e-76 spoVAA S Stage V sporulation protein AA
OOOKNECK_02333 1.3e-67 spoVAB S Stage V sporulation protein AB
OOOKNECK_02334 1.3e-78 spoVAC S stage V sporulation protein AC
OOOKNECK_02335 3.5e-188 spoVAD I Stage V sporulation protein AD
OOOKNECK_02336 2.5e-56 spoVAEB S stage V sporulation protein
OOOKNECK_02337 2.4e-107 spoVAEA S stage V sporulation protein
OOOKNECK_02338 6.2e-266 spoVAF EG Stage V sporulation protein AF
OOOKNECK_02339 6.5e-251 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
OOOKNECK_02340 2.6e-150 ypuA S Secreted protein
OOOKNECK_02341 5.7e-79 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OOOKNECK_02342 8.5e-79 ccdC1 O Protein of unknown function (DUF1453)
OOOKNECK_02343 3.9e-96 sipT 3.4.21.89 U Belongs to the peptidase S26 family
OOOKNECK_02344 5.1e-46 ypuD
OOOKNECK_02345 6.2e-202 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OOOKNECK_02346 7.2e-110 ribE 2.5.1.9 H Riboflavin synthase
OOOKNECK_02347 2.3e-226 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OOOKNECK_02348 5.6e-80 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
OOOKNECK_02349 1e-63 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOOKNECK_02350 6.2e-88 ypuF S Domain of unknown function (DUF309)
OOOKNECK_02352 3.1e-128 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
OOOKNECK_02353 5.1e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OOOKNECK_02354 8.1e-82 ypuI S Protein of unknown function (DUF3907)
OOOKNECK_02355 1.1e-209 dacB 3.4.16.4 M Belongs to the peptidase S11 family
OOOKNECK_02356 1.3e-102 spmA S Spore maturation protein
OOOKNECK_02357 3.8e-88 spmB S Spore maturation protein
OOOKNECK_02358 6.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OOOKNECK_02359 3.4e-97 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
OOOKNECK_02360 4.7e-73 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OOOKNECK_02361 9.9e-222 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
OOOKNECK_02362 1.5e-193 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
OOOKNECK_02363 8.8e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_02364 0.0 resE 2.7.13.3 T Histidine kinase
OOOKNECK_02365 2.2e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_02366 2.3e-169 rsiX
OOOKNECK_02367 9.1e-292 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOOKNECK_02368 1.6e-92 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
OOOKNECK_02369 3.6e-41 fer C Ferredoxin
OOOKNECK_02370 1.5e-189 ypbB 5.1.3.1 S protein conserved in bacteria
OOOKNECK_02371 2.5e-275 recQ 3.6.4.12 L DNA helicase
OOOKNECK_02372 2.4e-96 ypbD S metal-dependent membrane protease
OOOKNECK_02373 3.7e-60 ypbE M Lysin motif
OOOKNECK_02374 1.1e-83 ypbF S Protein of unknown function (DUF2663)
OOOKNECK_02375 1.9e-141 ypbG S Calcineurin-like phosphoesterase superfamily domain
OOOKNECK_02376 2.2e-105 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
OOOKNECK_02377 2e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
OOOKNECK_02378 2.1e-185 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
OOOKNECK_02379 1.6e-120 prsW S Involved in the degradation of specific anti-sigma factors
OOOKNECK_02380 4.7e-149 sleB 3.5.1.28 M Spore cortex-lytic enzyme
OOOKNECK_02381 2.1e-244 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
OOOKNECK_02382 1.1e-57 ypfA M Flagellar protein YcgR
OOOKNECK_02383 2.5e-12 S Family of unknown function (DUF5359)
OOOKNECK_02384 7.5e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
OOOKNECK_02385 2.1e-205 rpsA 1.17.7.4 J Ribosomal protein S1
OOOKNECK_02386 1.5e-178 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
OOOKNECK_02387 2.4e-99 yphA
OOOKNECK_02388 1.8e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
OOOKNECK_02389 5.2e-187 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
OOOKNECK_02390 1.5e-16 yphE S Protein of unknown function (DUF2768)
OOOKNECK_02391 7.1e-130 yphF
OOOKNECK_02392 1.3e-10 yphF
OOOKNECK_02393 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
OOOKNECK_02394 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
OOOKNECK_02395 5.4e-101 folE 3.5.4.16 H GTP cyclohydrolase
OOOKNECK_02396 1.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
OOOKNECK_02397 1.5e-135 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
OOOKNECK_02398 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
OOOKNECK_02399 4.8e-196 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
OOOKNECK_02400 2.2e-78 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
OOOKNECK_02401 7.4e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
OOOKNECK_02402 2.3e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OOOKNECK_02403 1.2e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OOOKNECK_02404 1.7e-58 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
OOOKNECK_02405 5.8e-283 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OOOKNECK_02406 6.3e-153 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OOOKNECK_02407 1.9e-122 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
OOOKNECK_02408 3.3e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
OOOKNECK_02409 5.6e-225 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
OOOKNECK_02410 5.5e-136 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
OOOKNECK_02411 3.1e-198 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OOOKNECK_02412 1.8e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
OOOKNECK_02413 1.3e-227 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
OOOKNECK_02414 1.5e-228 S COG0457 FOG TPR repeat
OOOKNECK_02415 8.1e-99 ypiB S Belongs to the UPF0302 family
OOOKNECK_02416 8.3e-73 ypiF S Protein of unknown function (DUF2487)
OOOKNECK_02417 8.7e-95 qcrA C Menaquinol-cytochrome c reductase
OOOKNECK_02418 6.7e-127 petB C COG1290 Cytochrome b subunit of the bc complex
OOOKNECK_02419 5.7e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
OOOKNECK_02420 5.2e-99 ypjA S membrane
OOOKNECK_02421 1.5e-138 ypjB S sporulation protein
OOOKNECK_02422 5.7e-222 oxdC 4.1.1.2 G Oxalate decarboxylase
OOOKNECK_02423 4.7e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_02424 1.8e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
OOOKNECK_02425 3.8e-145 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
OOOKNECK_02426 6.5e-63 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
OOOKNECK_02427 1e-125 bshB1 S proteins, LmbE homologs
OOOKNECK_02428 4.5e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
OOOKNECK_02429 5.6e-209 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
OOOKNECK_02430 4.9e-179 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
OOOKNECK_02431 2e-149 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
OOOKNECK_02432 1.2e-152 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OOOKNECK_02433 3.9e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OOOKNECK_02434 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
OOOKNECK_02435 6.7e-23 ypmA S Protein of unknown function (DUF4264)
OOOKNECK_02436 1.4e-73 ypmB S protein conserved in bacteria
OOOKNECK_02437 2.9e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
OOOKNECK_02438 7.1e-250 asnS 6.1.1.22 J asparaginyl-tRNA
OOOKNECK_02439 3.4e-129 dnaD L DNA replication protein DnaD
OOOKNECK_02440 7.8e-120 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OOOKNECK_02441 1.4e-86 ypoC
OOOKNECK_02442 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
OOOKNECK_02443 1.2e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
OOOKNECK_02444 9.2e-178 yppC S Protein of unknown function (DUF2515)
OOOKNECK_02447 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
OOOKNECK_02449 5e-39 yppG S YppG-like protein
OOOKNECK_02450 1.1e-60 hspX O Belongs to the small heat shock protein (HSP20) family
OOOKNECK_02451 1.3e-87 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
OOOKNECK_02452 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
OOOKNECK_02453 7.5e-225 yprB L RNase_H superfamily
OOOKNECK_02455 5.8e-28 cotD S Inner spore coat protein D
OOOKNECK_02456 5.9e-97 ypsA S Belongs to the UPF0398 family
OOOKNECK_02457 3.4e-46 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
OOOKNECK_02458 4e-91 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OOOKNECK_02459 3e-72 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
OOOKNECK_02460 2e-74 yqgA
OOOKNECK_02461 6.6e-22 S YpzG-like protein
OOOKNECK_02463 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
OOOKNECK_02464 1.9e-286 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OOOKNECK_02465 2.9e-94 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
OOOKNECK_02466 3.9e-232 pbuX F xanthine
OOOKNECK_02467 2.4e-07 S Bacillus cereus group antimicrobial protein
OOOKNECK_02468 6.6e-45 ybaZ 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
OOOKNECK_02469 2e-101 J Acetyltransferase (GNAT) domain
OOOKNECK_02470 1.2e-194 bcsA Q Naringenin-chalcone synthase
OOOKNECK_02471 4.8e-85 ypbQ S protein conserved in bacteria
OOOKNECK_02472 0.0 ypbR S Dynamin family
OOOKNECK_02473 3.7e-33 ypbS S Protein of unknown function (DUF2533)
OOOKNECK_02475 8e-160 polA 2.7.7.7 L 5'3' exonuclease
OOOKNECK_02477 7.1e-68 rnhA 3.1.26.4 L Ribonuclease
OOOKNECK_02478 5.2e-119 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OOOKNECK_02479 2e-118 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
OOOKNECK_02480 2.3e-35 S Protein of unknown function (DUF2564)
OOOKNECK_02482 1e-30 cspD K Cold-shock protein
OOOKNECK_02483 1.4e-212 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
OOOKNECK_02484 2.8e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
OOOKNECK_02486 2.1e-82 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
OOOKNECK_02487 2.3e-89 ypgQ S phosphohydrolase
OOOKNECK_02488 6e-152 ypgR C COG0694 Thioredoxin-like proteins and domains
OOOKNECK_02489 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
OOOKNECK_02490 1.7e-75 yphP S Belongs to the UPF0403 family
OOOKNECK_02491 2.4e-126 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
OOOKNECK_02492 3e-110 ypjP S YpjP-like protein
OOOKNECK_02493 2.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OOOKNECK_02494 7.8e-85 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OOOKNECK_02495 1.7e-108 ypkP 2.3.1.40, 2.3.1.51, 6.2.1.20 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
OOOKNECK_02496 6.6e-108 hlyIII S protein, Hemolysin III
OOOKNECK_02497 3.8e-163 pspF K Transcriptional regulator
OOOKNECK_02498 1.3e-240 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OOOKNECK_02499 7.5e-39 ypmP S Protein of unknown function (DUF2535)
OOOKNECK_02500 2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
OOOKNECK_02501 9.5e-130 ypmR E GDSL-like Lipase/Acylhydrolase
OOOKNECK_02502 1.7e-94 ypmS S protein conserved in bacteria
OOOKNECK_02503 3.1e-66 ypoP K transcriptional
OOOKNECK_02504 4.3e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OOOKNECK_02505 6.4e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
OOOKNECK_02506 1.2e-100 4.2.1.115 GM Polysaccharide biosynthesis protein
OOOKNECK_02507 6.4e-211 yokA L Recombinase
OOOKNECK_02508 1.9e-13 S Regulatory protein YrvL
OOOKNECK_02510 1.9e-121 lldD 1.13.12.4 C FMN-dependent dehydrogenase
OOOKNECK_02513 1.2e-69 4.2.1.115 GM Polysaccharide biosynthesis protein
OOOKNECK_02514 1.3e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
OOOKNECK_02515 2.9e-168 cgeB S Spore maturation protein
OOOKNECK_02516 6.2e-49 cgeA
OOOKNECK_02517 1.3e-34 cgeC
OOOKNECK_02518 1.1e-226 cgeD M maturation of the outermost layer of the spore
OOOKNECK_02519 1.3e-137 yiiD K acetyltransferase
OOOKNECK_02521 2.4e-64 yosT L Bacterial transcription activator, effector binding domain
OOOKNECK_02523 1e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOOKNECK_02524 3.1e-96 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
OOOKNECK_02525 2.7e-118 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
OOOKNECK_02526 1.6e-249 yodQ 3.5.1.16 E Acetylornithine deacetylase
OOOKNECK_02527 1.4e-140 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
OOOKNECK_02528 1.2e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
OOOKNECK_02529 1.1e-43 yokU S YokU-like protein, putative antitoxin
OOOKNECK_02530 3.4e-35 yozE S Belongs to the UPF0346 family
OOOKNECK_02531 6.1e-51 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_02532 5.6e-121 yodN
OOOKNECK_02534 1.8e-23 yozD S YozD-like protein
OOOKNECK_02535 4.4e-101 yodM 3.6.1.27 I Acid phosphatase homologues
OOOKNECK_02536 3.3e-55 yodL S YodL-like
OOOKNECK_02538 7.7e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
OOOKNECK_02539 7.6e-141 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
OOOKNECK_02540 1e-19 yodI
OOOKNECK_02541 2.2e-120 yodH Q Methyltransferase
OOOKNECK_02542 5.5e-248 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
OOOKNECK_02543 3.8e-128 yydK K Transcriptional regulator
OOOKNECK_02544 1.6e-282 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOOKNECK_02545 4.3e-267 3.2.1.45 GH30 M Glycosyl hydrolase family 30 beta sandwich domain
OOOKNECK_02546 3.2e-262 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOOKNECK_02547 3.1e-19 S Protein of unknown function (DUF3311)
OOOKNECK_02548 6.3e-168 yodE E COG0346 Lactoylglutathione lyase and related lyases
OOOKNECK_02549 5.3e-107 mhqD S Carboxylesterase
OOOKNECK_02550 5.5e-104 yodC C nitroreductase
OOOKNECK_02551 3.5e-52 yodB K transcriptional
OOOKNECK_02552 6.8e-63 yodA S tautomerase
OOOKNECK_02554 8.9e-78 yozR S COG0071 Molecular chaperone (small heat shock protein)
OOOKNECK_02555 2.6e-158 rarD S -transporter
OOOKNECK_02556 6.4e-23
OOOKNECK_02557 3.7e-60 yojF S Protein of unknown function (DUF1806)
OOOKNECK_02558 9.6e-126 yojG S deacetylase
OOOKNECK_02559 6.2e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOOKNECK_02560 1.1e-232 norM V Multidrug efflux pump
OOOKNECK_02562 2.3e-105 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OOOKNECK_02563 5.1e-218 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
OOOKNECK_02564 2.1e-214 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
OOOKNECK_02565 1.8e-99 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OOOKNECK_02566 6.5e-162 yojN S ATPase family associated with various cellular activities (AAA)
OOOKNECK_02567 0.0 yojO P Von Willebrand factor
OOOKNECK_02568 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
OOOKNECK_02569 2.9e-184 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
OOOKNECK_02570 1.4e-128 S Metallo-beta-lactamase superfamily
OOOKNECK_02571 3.6e-158 yocS S -transporter
OOOKNECK_02572 7.1e-229 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
OOOKNECK_02573 8.1e-162 sodA 1.15.1.1 P Superoxide dismutase
OOOKNECK_02574 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
OOOKNECK_02575 5.1e-284 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
OOOKNECK_02576 1.6e-31 yozC
OOOKNECK_02577 2.4e-56 yozO S Bacterial PH domain
OOOKNECK_02578 2.5e-36 yocN
OOOKNECK_02579 2e-29 yozN
OOOKNECK_02580 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
OOOKNECK_02581 9.8e-09
OOOKNECK_02582 6.3e-10 yocL
OOOKNECK_02583 2e-56 dksA T general stress protein
OOOKNECK_02584 1.1e-110 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOOKNECK_02586 0.0 recQ 3.6.4.12 L DNA helicase
OOOKNECK_02587 2.1e-112 yocH CBM50 M COG1388 FOG LysM repeat
OOOKNECK_02589 5.8e-180 yocD 3.4.17.13 V peptidase S66
OOOKNECK_02590 3.4e-91 yocC
OOOKNECK_02591 1.3e-134 yocB J Protein required for attachment to host cells
OOOKNECK_02592 1.4e-90 yozB S membrane
OOOKNECK_02593 3.3e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
OOOKNECK_02594 7.6e-55 czrA K transcriptional
OOOKNECK_02595 3.1e-44 yobW
OOOKNECK_02596 8.8e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
OOOKNECK_02597 7e-85 yobS K Transcriptional regulator
OOOKNECK_02598 3.4e-121 yobQ K helix_turn_helix, arabinose operon control protein
OOOKNECK_02599 4.6e-52 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
OOOKNECK_02602 1.1e-28
OOOKNECK_02603 1.1e-93 hpr K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_02605 5.7e-27 yoaF
OOOKNECK_02606 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOOKNECK_02607 1.5e-186 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OOOKNECK_02608 1.2e-264 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189 G FGGY family of carbohydrate kinases, C-terminal domain
OOOKNECK_02609 2.3e-194 yoaB EGP Major facilitator Superfamily
OOOKNECK_02612 4e-246 iolT EGP Major facilitator Superfamily
OOOKNECK_02613 1.6e-177 yhfP 1.1.1.1 C Quinone oxidoreductase
OOOKNECK_02614 1.7e-81 yndB S Activator of Hsp90 ATPase homolog 1-like protein
OOOKNECK_02615 1.4e-161 ydhU P Catalase
OOOKNECK_02616 8.2e-293 yveA E amino acid
OOOKNECK_02617 2e-98 yvdT K Transcriptional regulator
OOOKNECK_02618 3.1e-48 ykkC P Small Multidrug Resistance protein
OOOKNECK_02619 1.1e-47 sugE P Small Multidrug Resistance protein
OOOKNECK_02620 8.2e-208 yeaN P COG2807 Cyanate permease
OOOKNECK_02621 2.1e-112 K FCD
OOOKNECK_02622 3.1e-130 ydhQ K UTRA
OOOKNECK_02623 7.1e-193 pbuE EGP Major facilitator Superfamily
OOOKNECK_02624 1.2e-97 ydhK M Protein of unknown function (DUF1541)
OOOKNECK_02626 2.5e-245 pbpE V Beta-lactamase
OOOKNECK_02628 3.9e-218 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
OOOKNECK_02629 1.3e-112 ydhC K FCD
OOOKNECK_02630 5.7e-165 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
OOOKNECK_02631 7.5e-105 S Alpha/beta hydrolase family
OOOKNECK_02632 9.3e-107 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
OOOKNECK_02633 9.8e-116 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OOOKNECK_02634 2.2e-15 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OOOKNECK_02635 2.6e-141 bltR K helix_turn_helix, mercury resistance
OOOKNECK_02636 2e-77 bltD 2.3.1.57 K FR47-like protein
OOOKNECK_02637 1.1e-122 ydhB S membrane transporter protein
OOOKNECK_02638 6.2e-154 K Helix-turn-helix XRE-family like proteins
OOOKNECK_02639 2.8e-219 fabF_1 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
OOOKNECK_02640 2e-206 tcaB EGP Major facilitator Superfamily
OOOKNECK_02641 3.3e-195 gldA 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OOOKNECK_02642 2.3e-148 S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_02643 3.6e-91 ynaD J Acetyltransferase (GNAT) domain
OOOKNECK_02644 2.6e-289 expZ S ABC transporter
OOOKNECK_02645 1.2e-126 puuD S Peptidase C26
OOOKNECK_02646 2.3e-35 ydfJ S drug exporters of the RND superfamily
OOOKNECK_02647 8.4e-35 yraG
OOOKNECK_02648 8.4e-63 yraF M Spore coat protein
OOOKNECK_02649 9.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OOOKNECK_02650 3.1e-24 yraE
OOOKNECK_02651 2.6e-46 yraD M Spore coat protein
OOOKNECK_02652 9e-251 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_02653 5.7e-150 ydeK EG -transporter
OOOKNECK_02654 1.5e-98 ydeS K Transcriptional regulator
OOOKNECK_02655 7.4e-169 ydeR EGP Major facilitator Superfamily
OOOKNECK_02656 2.6e-101 paiB K Transcriptional regulator
OOOKNECK_02657 4.6e-247 K helix_turn_helix gluconate operon transcriptional repressor
OOOKNECK_02658 1.4e-218 mleN_2 C antiporter
OOOKNECK_02659 5e-61 yraB K helix_turn_helix, mercury resistance
OOOKNECK_02660 5.1e-198 adhA 1.1.1.1 C alcohol dehydrogenase
OOOKNECK_02661 1.3e-160 S Sodium Bile acid symporter family
OOOKNECK_02662 7.1e-47 ydeH
OOOKNECK_02663 2.6e-186 rlmN 2.1.1.192, 2.1.1.224 J Specifically methylates position 8 of adenine 2503 in 23S rRNA. Confers resistance to some classes of antibiotics
OOOKNECK_02665 6.6e-146 ydeE K AraC family transcriptional regulator
OOOKNECK_02666 1.8e-82 yyaR K Acetyltransferase (GNAT) domain
OOOKNECK_02667 5.8e-97 yrkC G Cupin domain
OOOKNECK_02668 1.4e-160 S SNARE associated Golgi protein
OOOKNECK_02669 2.9e-152 czcD P COG1230 Co Zn Cd efflux system component
OOOKNECK_02670 6.3e-70 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_02671 1.7e-254 ygaK C COG0277 FAD FMN-containing dehydrogenases
OOOKNECK_02673 7.5e-172 S Patatin-like phospholipase
OOOKNECK_02674 1.2e-188 ydeG EGP Major facilitator superfamily
OOOKNECK_02675 1.6e-236 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_02676 1.6e-49 K Transcriptional regulator PadR-like family
OOOKNECK_02677 3.1e-101 S Protein of unknown function (DUF2812)
OOOKNECK_02678 8.9e-111 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
OOOKNECK_02679 5.1e-30 cspL K Cold shock
OOOKNECK_02680 2.3e-95 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OOOKNECK_02681 8.2e-77 K Transcriptional regulator
OOOKNECK_02682 3.8e-54
OOOKNECK_02683 2.8e-13 S Domain of unknown function (DUF4367)
OOOKNECK_02684 2.8e-49 ohrR K Transcriptional regulator
OOOKNECK_02685 1.5e-47 ohrB O OsmC-like protein
OOOKNECK_02686 3.7e-139 I esterase
OOOKNECK_02694 1.4e-56 ydcK S Belongs to the SprT family
OOOKNECK_02695 1.7e-14
OOOKNECK_02696 0.0 yhgF K COG2183 Transcriptional accessory protein
OOOKNECK_02697 2.2e-105 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
OOOKNECK_02698 2e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OOOKNECK_02699 6.6e-84 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
OOOKNECK_02700 2.7e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
OOOKNECK_02701 1.8e-184 rsbU 3.1.3.3 KT phosphatase
OOOKNECK_02702 4.2e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
OOOKNECK_02703 1.8e-57 rsbS T antagonist
OOOKNECK_02704 3e-137 rsbR T Positive regulator of sigma-B
OOOKNECK_02705 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
OOOKNECK_02706 8.1e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
OOOKNECK_02707 3.9e-215 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OOOKNECK_02708 1.3e-179 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
OOOKNECK_02709 4.1e-54 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
OOOKNECK_02710 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
OOOKNECK_02711 6.6e-252 ydbT S Membrane
OOOKNECK_02712 4.6e-61 ydbS S Bacterial PH domain
OOOKNECK_02713 1.8e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
OOOKNECK_02714 8.9e-251 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
OOOKNECK_02715 1.3e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
OOOKNECK_02716 8.5e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OOOKNECK_02717 2.4e-119 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOOKNECK_02718 9.2e-10 S Fur-regulated basic protein A
OOOKNECK_02719 3.5e-12 S Fur-regulated basic protein B
OOOKNECK_02720 2.4e-113 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OOOKNECK_02721 4e-70 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
OOOKNECK_02722 4.6e-52 ydbL
OOOKNECK_02723 1.5e-127 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
OOOKNECK_02724 1.4e-167 ydbJ V ABC transporter, ATP-binding protein
OOOKNECK_02725 3.7e-156 ydbI S AI-2E family transporter
OOOKNECK_02726 3.2e-223 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOOKNECK_02727 2.9e-114 dctR T COG4565 Response regulator of citrate malate metabolism
OOOKNECK_02728 2.9e-293 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOOKNECK_02729 3.1e-195 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
OOOKNECK_02730 2.3e-153 ydbD P Catalase
OOOKNECK_02731 1.8e-57 ydbC S Domain of unknown function (DUF4937
OOOKNECK_02732 4.6e-55 ydbB G Cupin domain
OOOKNECK_02734 2.9e-135 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
OOOKNECK_02735 1.5e-51 yvaE P Small Multidrug Resistance protein
OOOKNECK_02736 5.8e-73 yvaD S Family of unknown function (DUF5360)
OOOKNECK_02737 1.1e-33 ydaT
OOOKNECK_02739 1.9e-223 mntH P H( )-stimulated, divalent metal cation uptake system
OOOKNECK_02740 4.7e-39
OOOKNECK_02743 2e-183 S Histidine kinase
OOOKNECK_02744 4.8e-69
OOOKNECK_02745 2.8e-87 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OOOKNECK_02746 7.1e-61 K acetyltransferase
OOOKNECK_02747 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
OOOKNECK_02748 0.0 ydaO E amino acid
OOOKNECK_02749 0.0 ydaN S Bacterial cellulose synthase subunit
OOOKNECK_02750 2.6e-228 ydaM M Glycosyl transferase family group 2
OOOKNECK_02751 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
OOOKNECK_02752 6.5e-143 ydaK T Diguanylate cyclase, GGDEF domain
OOOKNECK_02753 2.9e-188 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
OOOKNECK_02754 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OOOKNECK_02755 4.3e-74 lrpC K Transcriptional regulator
OOOKNECK_02756 1.5e-46 ydzA EGP Major facilitator Superfamily
OOOKNECK_02757 1.2e-135 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
OOOKNECK_02758 3.4e-76 ydaG 1.4.3.5 S general stress protein
OOOKNECK_02759 3e-113 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
OOOKNECK_02760 9.6e-94 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
OOOKNECK_02761 2.3e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_02762 7.4e-283 ydaB IQ acyl-CoA ligase
OOOKNECK_02763 0.0 mtlR K transcriptional regulator, MtlR
OOOKNECK_02764 6.8e-167 ydhF S Oxidoreductase
OOOKNECK_02765 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
OOOKNECK_02766 1.1e-53 yczJ S biosynthesis
OOOKNECK_02768 1.2e-112 ycsK E anatomical structure formation involved in morphogenesis
OOOKNECK_02769 4.3e-125 kipR K Transcriptional regulator
OOOKNECK_02770 9.7e-178 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
OOOKNECK_02771 1.7e-131 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
OOOKNECK_02772 1.1e-141 ycsI S Belongs to the D-glutamate cyclase family
OOOKNECK_02773 1.8e-207 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
OOOKNECK_02774 2.1e-132 ycsF S Belongs to the UPF0271 (lamB) family
OOOKNECK_02775 2.6e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
OOOKNECK_02777 2.7e-59 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
OOOKNECK_02778 9.6e-203 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OOOKNECK_02779 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
OOOKNECK_02780 2.8e-231 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
OOOKNECK_02781 3.9e-54
OOOKNECK_02782 5.8e-103 ycnK K COG1349 Transcriptional regulators of sugar metabolism
OOOKNECK_02783 1.8e-287 ycnJ P protein, homolog of Cu resistance protein CopC
OOOKNECK_02784 6.2e-95 ycnI S protein conserved in bacteria
OOOKNECK_02785 8.6e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_02786 2.6e-147 glcU U Glucose uptake
OOOKNECK_02787 1.3e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOOKNECK_02788 8.8e-120 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOOKNECK_02789 1.7e-91 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOOKNECK_02790 2.7e-255 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
OOOKNECK_02791 1.8e-50 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
OOOKNECK_02792 1.4e-44 ycnE S Monooxygenase
OOOKNECK_02793 1.4e-133 nfrA2 1.5.1.38, 1.5.1.39 C Nitroreductase family
OOOKNECK_02794 1.1e-148 ycnC K Transcriptional regulator
OOOKNECK_02795 8.1e-247 ycnB EGP Major facilitator Superfamily
OOOKNECK_02796 2.8e-171 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
OOOKNECK_02797 5.8e-135 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
OOOKNECK_02798 2.3e-165 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_02799 6.3e-163 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_02800 6.5e-246 lysC 2.7.2.4 E Belongs to the aspartokinase family
OOOKNECK_02803 2.7e-75 S aspartate phosphatase
OOOKNECK_02804 9.5e-256 T PhoQ Sensor
OOOKNECK_02805 9.9e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_02806 1.1e-222 yclI V ABC transporter (permease) YclI
OOOKNECK_02807 1.8e-119 yclH P ABC transporter
OOOKNECK_02808 4.1e-240 yxeQ S MmgE/PrpD family
OOOKNECK_02809 1.6e-213 yxeP 3.5.1.47 E hydrolase activity
OOOKNECK_02810 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
OOOKNECK_02811 1.7e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
OOOKNECK_02812 3.4e-138 yxeM M Belongs to the bacterial solute-binding protein 3 family
OOOKNECK_02813 2.2e-90 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
OOOKNECK_02814 3e-248 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_02815 9.3e-190 gerKB F Spore germination protein
OOOKNECK_02816 5.5e-228 gerKC S spore germination
OOOKNECK_02817 9.1e-265 gerKA EG Spore germination protein
OOOKNECK_02819 1.5e-263 yclG M Pectate lyase superfamily protein
OOOKNECK_02820 6.8e-265 dtpT E amino acid peptide transporter
OOOKNECK_02821 6.6e-73 yclD
OOOKNECK_02822 9.2e-36 bsdD 4.1.1.61 S response to toxic substance
OOOKNECK_02823 1.5e-280 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
OOOKNECK_02824 9.3e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
OOOKNECK_02825 1.4e-153 bsdA K LysR substrate binding domain
OOOKNECK_02826 1e-142 tcyA ET Belongs to the bacterial solute-binding protein 3 family
OOOKNECK_02827 1e-117 tcyB P COG0765 ABC-type amino acid transport system, permease component
OOOKNECK_02828 1.3e-131 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
OOOKNECK_02829 8e-106 yczE S membrane
OOOKNECK_02830 2.5e-121 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
OOOKNECK_02831 1.5e-247 bamJ E Aminotransferase class I and II
OOOKNECK_02832 1.3e-136 srfAD Q thioesterase
OOOKNECK_02833 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
OOOKNECK_02834 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_02835 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
OOOKNECK_02836 1.1e-62 hxlR K transcriptional
OOOKNECK_02837 1.2e-101 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
OOOKNECK_02838 1.3e-91 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
OOOKNECK_02839 4.2e-77 nucA M Deoxyribonuclease NucA/NucB
OOOKNECK_02840 4.3e-65 nin S Competence protein J (ComJ)
OOOKNECK_02841 2.3e-286 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
OOOKNECK_02842 3.5e-49 S Protein of unknown function (DUF2680)
OOOKNECK_02843 5.2e-72 yckC S membrane
OOOKNECK_02844 1.7e-218 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
OOOKNECK_02845 3.4e-222 yciC S GTPases (G3E family)
OOOKNECK_02846 2.7e-39 nasA P COG2223 Nitrate nitrite transporter
OOOKNECK_02847 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OOOKNECK_02848 1.5e-55 nirD 1.7.1.15 P Nitrite reductase
OOOKNECK_02849 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
OOOKNECK_02850 2.4e-184 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
OOOKNECK_02851 3.7e-224 ycgP QT COG2508 Regulator of polyketide synthase expression
OOOKNECK_02852 3.2e-243 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOOKNECK_02853 7.6e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
OOOKNECK_02854 6.2e-168 ycgM E Proline dehydrogenase
OOOKNECK_02855 7.6e-138 ycgL S Predicted nucleotidyltransferase
OOOKNECK_02856 2.6e-180 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
OOOKNECK_02857 3.3e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OOOKNECK_02858 4.1e-221 G COG0477 Permeases of the major facilitator superfamily
OOOKNECK_02859 3.8e-129 4.2.1.118 G Xylose isomerase-like TIM barrel
OOOKNECK_02860 3.2e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
OOOKNECK_02861 4.3e-76 ycgI S Domain of unknown function (DUF1989)
OOOKNECK_02862 1.6e-22 ycgI S Domain of unknown function (DUF1989)
OOOKNECK_02863 4.5e-239 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_02864 1.1e-80 yqcI S YqcI/YcgG family
OOOKNECK_02865 1.6e-52 yqcI S YqcI/YcgG family
OOOKNECK_02866 6.1e-101 ycgF E Lysine exporter protein LysE YggA
OOOKNECK_02867 2.9e-73 emrR K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_02868 9.9e-259 mdr EGP Major facilitator Superfamily
OOOKNECK_02869 1.7e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
OOOKNECK_02870 7.9e-13 S RDD family
OOOKNECK_02871 5.2e-42 ycgB
OOOKNECK_02872 3.9e-225 ycgA S Membrane
OOOKNECK_02873 2.7e-205 amhX S amidohydrolase
OOOKNECK_02874 4.2e-161 opuAC E glycine betaine
OOOKNECK_02875 1.8e-137 opuAB P glycine betaine
OOOKNECK_02876 9e-226 proV 3.6.3.32 E glycine betaine
OOOKNECK_02878 1.4e-207 naiP P Uncharacterised MFS-type transporter YbfB
OOOKNECK_02879 4.3e-192 yceH P Belongs to the TelA family
OOOKNECK_02880 1.3e-306 yceG S Putative component of 'biosynthetic module'
OOOKNECK_02881 1.7e-137 terC P Protein of unknown function (DUF475)
OOOKNECK_02882 3.3e-106 yceE T proteins involved in stress response, homologs of TerZ and
OOOKNECK_02883 6.3e-105 yceD T proteins involved in stress response, homologs of TerZ and
OOOKNECK_02884 6.2e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
OOOKNECK_02885 1.4e-181 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OOOKNECK_02886 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
OOOKNECK_02887 1.6e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
OOOKNECK_02888 1.1e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
OOOKNECK_02889 1.5e-47 padR K Virulence activator alpha C-term
OOOKNECK_02890 1.6e-48 S Domain of unknown function (DUF4188)
OOOKNECK_02891 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
OOOKNECK_02892 2e-135 IQ Enoyl-(Acyl carrier protein) reductase
OOOKNECK_02893 2e-171 S response regulator aspartate phosphatase
OOOKNECK_02894 1.6e-88 cwlK M D-alanyl-D-alanine carboxypeptidase
OOOKNECK_02895 3e-251 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_02896 1.1e-235 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_02897 2.7e-164 ycdA S Domain of unknown function (DUF5105)
OOOKNECK_02898 1e-165 yccK C Aldo keto reductase
OOOKNECK_02899 8e-191 yccF K DNA-templated transcriptional preinitiation complex assembly
OOOKNECK_02900 6.4e-16 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OOOKNECK_02901 7.5e-46 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
OOOKNECK_02902 3.6e-97 yxaF K Transcriptional regulator
OOOKNECK_02903 1.7e-236 lmrB EGP the major facilitator superfamily
OOOKNECK_02904 1.2e-189 ycbU E Selenocysteine lyase
OOOKNECK_02905 5.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OOOKNECK_02906 9e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OOOKNECK_02907 4.4e-26 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OOOKNECK_02908 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
OOOKNECK_02909 4.8e-78 sleB 3.5.1.28 M Cell wall
OOOKNECK_02910 7.4e-62 ycbP S Protein of unknown function (DUF2512)
OOOKNECK_02911 3.5e-55 traF CO Thioredoxin
OOOKNECK_02912 7.5e-62 mhqP S DoxX
OOOKNECK_02913 6.8e-136 ydfO E COG0346 Lactoylglutathione lyase and related lyases
OOOKNECK_02914 3.5e-91 ydfN C nitroreductase
OOOKNECK_02915 1.3e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOOKNECK_02916 4.5e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
OOOKNECK_02917 3.5e-126 ycbJ S Macrolide 2'-phosphotransferase
OOOKNECK_02918 1.7e-155 glnL T Regulator
OOOKNECK_02919 5.7e-199 phoQ 2.7.13.3 T Histidine kinase
OOOKNECK_02920 3.8e-153 glsA 3.5.1.2 E Belongs to the glutaminase family
OOOKNECK_02921 1.9e-251 agcS E Sodium alanine symporter
OOOKNECK_02922 7.7e-177 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
OOOKNECK_02923 7.2e-237 mmuP E amino acid
OOOKNECK_02924 2.3e-193 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
OOOKNECK_02925 4.7e-175 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
OOOKNECK_02926 2.6e-188 yceA S Belongs to the UPF0176 family
OOOKNECK_02927 2.8e-39 ybfN
OOOKNECK_02928 9e-150 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
OOOKNECK_02929 5.1e-84 ybfM S SNARE associated Golgi protein
OOOKNECK_02930 1.9e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OOOKNECK_02931 1.7e-207 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OOOKNECK_02932 7e-187 gldA 1.1.1.1, 1.1.1.6 C COG0371 Glycerol dehydrogenase and related enzymes
OOOKNECK_02933 3.9e-81 K Helix-turn-helix XRE-family like proteins
OOOKNECK_02935 9.5e-211 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
OOOKNECK_02936 2.7e-17 S Protein of unknown function (DUF2651)
OOOKNECK_02937 1.6e-257 glpT G -transporter
OOOKNECK_02938 2e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
OOOKNECK_02939 1.2e-15 S Protein of unknown function (DUF2651)
OOOKNECK_02940 1.2e-275 ybeC E amino acid
OOOKNECK_02941 2.3e-38 ybyB
OOOKNECK_02942 3.6e-99 yqeB
OOOKNECK_02943 1.3e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
OOOKNECK_02944 1.5e-75 S Domain of unknown function (DUF4879)
OOOKNECK_02945 9.2e-23
OOOKNECK_02946 1.8e-180 V ABC-2 family transporter protein
OOOKNECK_02947 8.4e-189 V COG0842 ABC-type multidrug transport system, permease component
OOOKNECK_02948 7e-130 V COG1131 ABC-type multidrug transport system, ATPase component
OOOKNECK_02949 3e-100 KT LuxR family transcriptional regulator
OOOKNECK_02950 4.8e-178 T COG4585 Signal transduction histidine kinase
OOOKNECK_02951 3.6e-94 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
OOOKNECK_02952 7.1e-256 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_02953 7.7e-68 yxaD K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_02954 2.2e-50 S LrgA family
OOOKNECK_02955 1.5e-92 yxaC M effector of murein hydrolase
OOOKNECK_02956 4.9e-159 dkgB S Aldo/keto reductase family
OOOKNECK_02957 2.9e-133 ybdO S Domain of unknown function (DUF4885)
OOOKNECK_02958 6e-99 ybdN
OOOKNECK_02959 1.1e-52 S ABC-2 family transporter protein
OOOKNECK_02960 1.4e-132 O growth
OOOKNECK_02961 2e-57 L replication factor c
OOOKNECK_02962 6.5e-47
OOOKNECK_02963 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
OOOKNECK_02964 2.3e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OOOKNECK_02965 1.9e-216 ybbR S protein conserved in bacteria
OOOKNECK_02966 3.9e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
OOOKNECK_02967 5.2e-113 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
OOOKNECK_02968 1.4e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_02970 1.5e-07
OOOKNECK_02974 1.2e-74 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
OOOKNECK_02975 2.3e-81 ybbJ J acetyltransferase
OOOKNECK_02976 8.3e-160 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OOOKNECK_02977 1.8e-196 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_02978 1.5e-236 yfeW 3.4.16.4 V Belongs to the UPF0214 family
OOOKNECK_02979 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
OOOKNECK_02980 7.8e-230 ybbC 3.2.1.52 S protein conserved in bacteria
OOOKNECK_02981 1.3e-290 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
OOOKNECK_02982 2e-169 feuA P Iron-uptake system-binding protein
OOOKNECK_02983 6.9e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_02984 3.3e-19 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_02985 7.5e-144 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OOOKNECK_02986 2.2e-102 ybbA S Putative esterase
OOOKNECK_02987 3.2e-170 ybaS 1.1.1.58 S Na -dependent transporter
OOOKNECK_02988 1.1e-222 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
OOOKNECK_02989 2.9e-201 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
OOOKNECK_02990 2.2e-176 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
OOOKNECK_02991 1e-245 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
OOOKNECK_02992 2.2e-213 glcP G Major Facilitator Superfamily
OOOKNECK_02993 8.5e-162 ygxA S Nucleotidyltransferase-like
OOOKNECK_02994 2.1e-55 ygzB S UPF0295 protein
OOOKNECK_02995 3.1e-80 perR P Belongs to the Fur family
OOOKNECK_02996 5e-84 bcp 1.11.1.15 O Peroxiredoxin
OOOKNECK_02997 1.1e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
OOOKNECK_02998 5e-177 ygaE S Membrane
OOOKNECK_02999 3.1e-301 ygaD V ABC transporter
OOOKNECK_03000 2.2e-104 ygaC J Belongs to the UPF0374 family
OOOKNECK_03001 4.4e-37 ygaB S YgaB-like protein
OOOKNECK_03003 2e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_03004 1.8e-36 yfhS
OOOKNECK_03005 1.4e-203 mutY L A G-specific
OOOKNECK_03006 5.9e-180 yfhP S membrane-bound metal-dependent
OOOKNECK_03007 0.0 yfhO S Bacterial membrane protein YfhO
OOOKNECK_03008 5.1e-184 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOOKNECK_03009 2.5e-166 yfhM S Alpha/beta hydrolase family
OOOKNECK_03010 3.4e-31 yfhL S SdpI/YhfL protein family
OOOKNECK_03011 1.1e-87 batE T Bacterial SH3 domain homologues
OOOKNECK_03012 8.3e-44 yfhJ S WVELL protein
OOOKNECK_03013 3.7e-160 mpr 3.4.21.19 M Belongs to the peptidase S1B family
OOOKNECK_03015 4.4e-112 yfhI EGP Major facilitator Superfamily
OOOKNECK_03016 4.7e-46 yfhH S Protein of unknown function (DUF1811)
OOOKNECK_03017 7.3e-89 recX 2.4.1.337 GT4 S Modulates RecA activity
OOOKNECK_03018 1.1e-38 recX 2.4.1.337 GT4 S Modulates RecA activity
OOOKNECK_03019 2.1e-163 yfhF S nucleoside-diphosphate sugar epimerase
OOOKNECK_03021 1e-24 yfhD S YfhD-like protein
OOOKNECK_03022 5.9e-103 yfhC C nitroreductase
OOOKNECK_03023 5.5e-153 yfhB 5.3.3.17 S PhzF family
OOOKNECK_03024 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OOOKNECK_03025 1.4e-78 yfiV K transcriptional
OOOKNECK_03026 6.4e-285 yfiU EGP Major facilitator Superfamily
OOOKNECK_03027 6.1e-94 yfiT S Belongs to the metal hydrolase YfiT family
OOOKNECK_03028 2.2e-44 yrdF K ribonuclease inhibitor
OOOKNECK_03029 8.5e-172 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
OOOKNECK_03030 9.7e-101 1.6.5.2 S NADPH-dependent FMN reductase
OOOKNECK_03031 2e-92 padR K transcriptional
OOOKNECK_03032 1.7e-70 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OOOKNECK_03033 3.7e-77 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
OOOKNECK_03034 1.5e-155 yfiE 1.13.11.2 S glyoxalase
OOOKNECK_03035 9.2e-63 mhqP S DoxX
OOOKNECK_03036 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
OOOKNECK_03037 1.9e-303 yfiB3 V ABC transporter
OOOKNECK_03038 0.0 M Peptidase_G2, IMC autoproteolytic cleavage domain
OOOKNECK_03039 2.4e-292 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_03040 4.3e-138 glvR F Helix-turn-helix domain, rpiR family
OOOKNECK_03041 1e-259 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
OOOKNECK_03042 3.2e-15 sspH S Belongs to the SspH family
OOOKNECK_03043 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
OOOKNECK_03044 3.9e-238 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
OOOKNECK_03045 6.8e-207 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
OOOKNECK_03046 2e-186 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
OOOKNECK_03047 2.5e-186 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
OOOKNECK_03048 6e-79 yfjM S Psort location Cytoplasmic, score
OOOKNECK_03049 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOOKNECK_03050 4.7e-45 S YfzA-like protein
OOOKNECK_03058 0.0 KLT Protein kinase domain
OOOKNECK_03059 1.3e-246 lmrA 3.6.3.44 V ABC transporter
OOOKNECK_03060 7.4e-80 O Subtilase family
OOOKNECK_03061 3.4e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OOOKNECK_03062 2.8e-157 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OOOKNECK_03063 2.5e-183 corA P Mediates influx of magnesium ions
OOOKNECK_03064 2.1e-29
OOOKNECK_03065 1.5e-139 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
OOOKNECK_03066 4.9e-153 pdaA G deacetylase
OOOKNECK_03067 4.9e-27 yfjT
OOOKNECK_03068 1.1e-217 yfkA S YfkB-like domain
OOOKNECK_03069 2.6e-144 yfkC M Mechanosensitive ion channel
OOOKNECK_03070 4.3e-141 yfkD S YfkD-like protein
OOOKNECK_03071 8e-183 cax P COG0387 Ca2 H antiporter
OOOKNECK_03072 1.7e-213 ycaD EGP COG0477 Permeases of the major facilitator superfamily
OOOKNECK_03073 1.4e-142 yihY S Belongs to the UPF0761 family
OOOKNECK_03074 1.5e-47 yfkI S gas vesicle protein
OOOKNECK_03075 3.9e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
OOOKNECK_03076 3.9e-28 yfkK S Belongs to the UPF0435 family
OOOKNECK_03077 8.4e-189 ydiM EGP Major facilitator Superfamily
OOOKNECK_03078 4e-128 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
OOOKNECK_03079 3.2e-161 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OOOKNECK_03080 2.6e-178 K helix_turn _helix lactose operon repressor
OOOKNECK_03081 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
OOOKNECK_03082 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases
OOOKNECK_03083 6.8e-185 yibE S YibE/F-like protein
OOOKNECK_03084 3.8e-118 yibF S YibE/F-like protein
OOOKNECK_03085 4.6e-120 yfkO C nitroreductase
OOOKNECK_03086 6.1e-126 treR K transcriptional
OOOKNECK_03087 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
OOOKNECK_03088 2.3e-238 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
OOOKNECK_03089 1.2e-39 ydgB S Spore germination protein gerPA/gerPF
OOOKNECK_03090 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
OOOKNECK_03091 4.5e-76 cotP O Belongs to the small heat shock protein (HSP20) family
OOOKNECK_03092 4.7e-61 yhdN S Domain of unknown function (DUF1992)
OOOKNECK_03093 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOOKNECK_03094 8.2e-73 yfmQ S Uncharacterised protein from bacillus cereus group
OOOKNECK_03095 2.4e-240 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
OOOKNECK_03096 6.8e-136 map 3.4.11.18 E Methionine aminopeptidase
OOOKNECK_03097 9e-50 yflH S Protein of unknown function (DUF3243)
OOOKNECK_03098 1.6e-18 yflI
OOOKNECK_03099 1.5e-14 yflJ S Protein of unknown function (DUF2639)
OOOKNECK_03100 2.3e-119 yflK S protein conserved in bacteria
OOOKNECK_03101 1.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
OOOKNECK_03102 1.9e-211 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
OOOKNECK_03103 4.6e-143 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
OOOKNECK_03104 7.4e-223 citM C Citrate transporter
OOOKNECK_03105 1.7e-171 yflP S Tripartite tricarboxylate transporter family receptor
OOOKNECK_03106 6e-115 citT T response regulator
OOOKNECK_03107 7.9e-267 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
OOOKNECK_03108 4.6e-80 srtA 3.4.22.70 M Sortase family
OOOKNECK_03109 0.0 M1-568 M cell wall anchor domain
OOOKNECK_03110 4.8e-151 M1-574 T Transcriptional regulatory protein, C terminal
OOOKNECK_03111 0.0 ywpD T PhoQ Sensor
OOOKNECK_03112 5.2e-76 M1-820 Q Collagen triple helix repeat (20 copies)
OOOKNECK_03113 1.2e-19 Q calcium- and calmodulin-responsive adenylate cyclase activity
OOOKNECK_03115 3.7e-26 Q PFAM Collagen triple helix
OOOKNECK_03116 1e-233 yflS P Sodium:sulfate symporter transmembrane region
OOOKNECK_03117 3.1e-234 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
OOOKNECK_03118 1.3e-57 yflT S Heat induced stress protein YflT
OOOKNECK_03119 3.9e-25 S Protein of unknown function (DUF3212)
OOOKNECK_03120 1.9e-181 yfmJ S N-terminal domain of oxidoreductase
OOOKNECK_03121 1.8e-201 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
OOOKNECK_03122 4.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOOKNECK_03123 3.2e-196 yfmO EGP Major facilitator Superfamily
OOOKNECK_03124 5.8e-68 yfmP K transcriptional
OOOKNECK_03125 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
OOOKNECK_03126 6.5e-201 M COG0463 Glycosyltransferases involved in cell wall biogenesis
OOOKNECK_03127 6.4e-165 IQ Enoyl-(Acyl carrier protein) reductase
OOOKNECK_03128 1.1e-105 yfmS NT chemotaxis protein
OOOKNECK_03129 3.2e-275 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
OOOKNECK_03130 7.6e-242 yfnA E amino acid
OOOKNECK_03131 1e-213 fsr P COG0477 Permeases of the major facilitator superfamily
OOOKNECK_03132 4.5e-177 yfnD M Nucleotide-diphospho-sugar transferase
OOOKNECK_03133 4.3e-214 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
OOOKNECK_03134 8.4e-173 yfnF M Nucleotide-diphospho-sugar transferase
OOOKNECK_03135 9.2e-172 yfnG 4.2.1.45 M dehydratase
OOOKNECK_03136 4.3e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
OOOKNECK_03137 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
OOOKNECK_03139 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
OOOKNECK_03140 1.7e-196 yetN S Protein of unknown function (DUF3900)
OOOKNECK_03141 8.1e-194 yetM CH FAD binding domain
OOOKNECK_03142 4.9e-85 yetL K helix_turn_helix multiple antibiotic resistance protein
OOOKNECK_03143 2e-104 yetJ S Belongs to the BI1 family
OOOKNECK_03144 2.4e-55 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase activity
OOOKNECK_03145 1.4e-20 yezD S Uncharacterized small protein (DUF2292)
OOOKNECK_03146 1.5e-53 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOOKNECK_03147 3.6e-80 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
OOOKNECK_03148 7e-62 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_03149 7e-53 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
OOOKNECK_03150 3e-114 yetF S membrane
OOOKNECK_03152 2.2e-88 yesJ K Acetyltransferase (GNAT) family
OOOKNECK_03153 2e-103 cotJC P Spore Coat
OOOKNECK_03154 1.3e-44 cotJB S CotJB protein
OOOKNECK_03155 9.1e-45 cotJA S Spore coat associated protein JA (CotJA)
OOOKNECK_03156 1.6e-109 aadK G Streptomycin adenylyltransferase
OOOKNECK_03158 1.2e-126 yeeN K transcriptional regulatory protein
OOOKNECK_03159 1.3e-120 yobL L Belongs to the WXG100 family
OOOKNECK_03160 7.8e-198 yobL L nucleic acid phosphodiester bond hydrolysis
OOOKNECK_03161 1.9e-51 S Protein of unknown function, DUF600
OOOKNECK_03162 1.5e-56 S Protein of unknown function, DUF600
OOOKNECK_03163 2e-38 S Protein of unknown function, DUF600
OOOKNECK_03164 1.4e-137 cylB V ABC-2 type transporter
OOOKNECK_03165 8.5e-160 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
OOOKNECK_03166 5.4e-310 L Uncharacterized conserved protein (DUF2075)
OOOKNECK_03167 1.6e-247 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OOOKNECK_03168 7.4e-169 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
OOOKNECK_03169 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OOOKNECK_03170 1.1e-147 yerO K Transcriptional regulator
OOOKNECK_03171 1.5e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOOKNECK_03172 2e-272 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
OOOKNECK_03173 1.6e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOOKNECK_03174 4.9e-263 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OOOKNECK_03175 3.1e-119 sapB S MgtC SapB transporter
OOOKNECK_03176 5.4e-181 yerI S homoserine kinase type II (protein kinase fold)
OOOKNECK_03177 5.2e-223 camS S COG4851 Protein involved in sex pheromone biosynthesis
OOOKNECK_03178 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OOOKNECK_03179 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
OOOKNECK_03180 9e-127 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
OOOKNECK_03181 6.1e-296 yerD 1.4.7.1 E Belongs to the glutamate synthase family
OOOKNECK_03182 2.4e-50 yerC S protein conserved in bacteria
OOOKNECK_03183 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
OOOKNECK_03184 0.0 yerA 3.5.4.2 F adenine deaminase
OOOKNECK_03185 5.4e-25 S Protein of unknown function (DUF2892)
OOOKNECK_03186 4.2e-135 yjeH E Amino acid permease
OOOKNECK_03187 3.8e-62 K helix_turn_helix ASNC type
OOOKNECK_03188 2.1e-230 purD 6.3.4.13 F Belongs to the GARS family
OOOKNECK_03189 2.8e-285 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
OOOKNECK_03190 8.5e-102 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OOOKNECK_03191 2.5e-181 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
OOOKNECK_03192 9.8e-269 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OOOKNECK_03193 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOOKNECK_03194 1.5e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOOKNECK_03195 2.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OOOKNECK_03196 8e-126 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
OOOKNECK_03197 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OOOKNECK_03198 5.3e-220 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OOOKNECK_03199 2.2e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OOOKNECK_03200 2.1e-28 yebG S NETI protein
OOOKNECK_03201 5.9e-78 yebE S UPF0316 protein
OOOKNECK_03203 2.6e-122 yebC M Membrane
OOOKNECK_03204 4e-208 pbuG S permease
OOOKNECK_03205 8.2e-247 S Domain of unknown function (DUF4179)
OOOKNECK_03206 5.2e-90 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_03207 6.2e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
OOOKNECK_03208 0.0 yebA E COG1305 Transglutaminase-like enzymes
OOOKNECK_03209 1.2e-198 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
OOOKNECK_03210 3e-176 yeaC S COG0714 MoxR-like ATPases
OOOKNECK_03211 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOOKNECK_03212 3.9e-238 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_03213 8.9e-220 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OOOKNECK_03214 4.7e-63 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
OOOKNECK_03215 3.2e-34 ydjO S Cold-inducible protein YdjO
OOOKNECK_03217 1.8e-131 ydjN U Involved in the tonB-independent uptake of proteins
OOOKNECK_03218 4.2e-62 ydjM M Lytic transglycolase
OOOKNECK_03219 6.4e-193 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
OOOKNECK_03220 9.5e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
OOOKNECK_03221 2.6e-139 rsiV S Protein of unknown function (DUF3298)
OOOKNECK_03222 0.0 yrhL I Acyltransferase family
OOOKNECK_03223 1.2e-143 ydjI S virion core protein (lumpy skin disease virus)
OOOKNECK_03224 1.1e-114 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
OOOKNECK_03225 1.7e-174 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OOOKNECK_03226 3.1e-111 pspA KT Phage shock protein A
OOOKNECK_03227 1.1e-29 yjdJ S Domain of unknown function (DUF4306)
OOOKNECK_03228 1.6e-169 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
OOOKNECK_03229 9.9e-228 gutA G MFS/sugar transport protein
OOOKNECK_03230 1.5e-197 gutB 1.1.1.14 E Dehydrogenase
OOOKNECK_03231 0.0 K NB-ARC domain
OOOKNECK_03232 5.7e-62
OOOKNECK_03234 0.0 ybfG 3.2.1.132 M Putative peptidoglycan binding domain
OOOKNECK_03235 1.8e-16
OOOKNECK_03236 7e-52 V Abortive infection bacteriophage resistance protein
OOOKNECK_03237 6.1e-40
OOOKNECK_03238 7.7e-16
OOOKNECK_03239 8.2e-72 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_03240 2.2e-59 S Pfam:Phage_holin_4_1
OOOKNECK_03244 1.1e-200 sidC L Phage minor structural protein
OOOKNECK_03245 3.5e-47
OOOKNECK_03246 1.8e-48 S Phage-related minor tail protein
OOOKNECK_03247 6.3e-136
OOOKNECK_03248 1.9e-25 S Phage tail assembly chaperone protein, TAC
OOOKNECK_03249 1.3e-34 S Phage tail tube protein
OOOKNECK_03250 3.8e-29 S Protein of unknown function (DUF3168)
OOOKNECK_03251 6.2e-38 S Bacteriophage HK97-gp10, putative tail-component
OOOKNECK_03252 5.6e-29 S Phage head-tail joining protein
OOOKNECK_03253 3.5e-27 S Phage gp6-like head-tail connector protein
OOOKNECK_03256 2.9e-54 gpG
OOOKNECK_03257 5.4e-44 S Phage minor structural protein GP20
OOOKNECK_03259 1.5e-92 S Phage Mu protein F like protein
OOOKNECK_03260 1.1e-126 S Phage portal protein, SPP1 Gp6-like
OOOKNECK_03261 6.4e-179 S Pfam:Terminase_3C
OOOKNECK_03262 2.4e-53 yqaS L DNA packaging
OOOKNECK_03267 1.6e-08
OOOKNECK_03274 1.3e-09
OOOKNECK_03275 7.8e-08
OOOKNECK_03284 4.8e-71 tspO T membrane
OOOKNECK_03285 2.3e-125 dksA T COG1734 DnaK suppressor protein
OOOKNECK_03286 3.7e-260 menF 5.4.4.2 HQ Isochorismate synthase
OOOKNECK_03287 3.9e-81 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OOOKNECK_03288 2.8e-235 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OOOKNECK_03289 1.9e-147 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
OOOKNECK_03290 7.9e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OOOKNECK_03291 1.7e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
OOOKNECK_03292 2e-208 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
OOOKNECK_03293 4e-24 S Domain of Unknown Function (DUF1540)
OOOKNECK_03294 1.2e-183 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
OOOKNECK_03295 1.2e-239 cydA 1.10.3.14 C oxidase, subunit
OOOKNECK_03296 7.9e-41 rpmE2 J Ribosomal protein L31
OOOKNECK_03297 1.3e-102 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
OOOKNECK_03298 2e-38 yidD S Could be involved in insertion of integral membrane proteins into the membrane
OOOKNECK_03299 2.2e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
OOOKNECK_03300 6.7e-75 ytkA S YtkA-like
OOOKNECK_03302 7.8e-76 dps P Belongs to the Dps family
OOOKNECK_03303 1.2e-59 ytkC S Bacteriophage holin family
OOOKNECK_03304 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
OOOKNECK_03305 3.8e-124 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
OOOKNECK_03306 2.1e-61 ytlC P ABC transporter
OOOKNECK_03307 8e-66 ytlC P ABC transporter
OOOKNECK_03308 1.9e-178 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
OOOKNECK_03309 2.2e-145 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
OOOKNECK_03310 8e-38 ytmB S Protein of unknown function (DUF2584)
OOOKNECK_03311 3e-303 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OOOKNECK_03312 1.5e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OOOKNECK_03313 0.0 asnB 6.3.5.4 E Asparagine synthase
OOOKNECK_03314 8.5e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
OOOKNECK_03315 1.8e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OOOKNECK_03316 9.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
OOOKNECK_03317 7.3e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
OOOKNECK_03319 3.4e-103 ytqB J Putative rRNA methylase
OOOKNECK_03320 1.4e-189 yhcC S Fe-S oxidoreductase
OOOKNECK_03321 8.1e-39 ytzC S Protein of unknown function (DUF2524)
OOOKNECK_03323 4.3e-65 ytrA K GntR family transcriptional regulator
OOOKNECK_03324 1.4e-156 ytrB P abc transporter atp-binding protein
OOOKNECK_03325 1.9e-162 S ABC-2 family transporter protein
OOOKNECK_03326 7.8e-148 P ABC-2 family transporter protein
OOOKNECK_03327 1.1e-144
OOOKNECK_03328 1.1e-124 ytrE V ABC transporter, ATP-binding protein
OOOKNECK_03329 5.8e-199 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
OOOKNECK_03330 1.1e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_03331 7.4e-162 T PhoQ Sensor
OOOKNECK_03332 7.8e-132 bceA V ABC transporter, ATP-binding protein
OOOKNECK_03333 0.0 bceB V ABC transporter (permease)
OOOKNECK_03334 4.2e-119 ywaF S Integral membrane protein
OOOKNECK_03335 4.9e-205 yttB EGP Major facilitator Superfamily
OOOKNECK_03336 3.5e-135 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
OOOKNECK_03337 1.2e-52 ytvB S Protein of unknown function (DUF4257)
OOOKNECK_03338 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
OOOKNECK_03339 1.3e-51 ytwF P Sulfurtransferase
OOOKNECK_03340 1.1e-73 M Acetyltransferase (GNAT) domain
OOOKNECK_03341 8.1e-246 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
OOOKNECK_03342 1.5e-141 amyC P ABC transporter (permease)
OOOKNECK_03343 5.5e-164 amyD G Binding-protein-dependent transport system inner membrane component
OOOKNECK_03344 4.1e-234 msmE G Bacterial extracellular solute-binding protein
OOOKNECK_03345 7.2e-181 msmR K Transcriptional regulator
OOOKNECK_03346 2.6e-25 yteV S Sporulation protein Cse60
OOOKNECK_03347 1.4e-276 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
OOOKNECK_03348 5.5e-231 ytfP S HI0933-like protein
OOOKNECK_03349 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_03350 2e-124 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
OOOKNECK_03351 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
OOOKNECK_03352 1.9e-116 ythP V ABC transporter
OOOKNECK_03353 1.5e-198 ythQ U Bacterial ABC transporter protein EcsB
OOOKNECK_03354 5.5e-226 pbuO S permease
OOOKNECK_03355 6.2e-260 pepV 3.5.1.18 E Dipeptidase
OOOKNECK_03356 1.6e-166 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OOOKNECK_03357 2.4e-98 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OOOKNECK_03358 5.1e-141 ytlQ
OOOKNECK_03359 2.6e-169 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
OOOKNECK_03360 4.1e-155 ytmP 2.7.1.89 M Phosphotransferase
OOOKNECK_03361 1.3e-44 ytzH S YtzH-like protein
OOOKNECK_03362 1.5e-123 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
OOOKNECK_03363 3.4e-160 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
OOOKNECK_03364 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
OOOKNECK_03365 1.7e-51 ytzB S small secreted protein
OOOKNECK_03366 4.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
OOOKNECK_03367 4.7e-76 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
OOOKNECK_03368 3.5e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
OOOKNECK_03369 3e-145 ytpQ S Belongs to the UPF0354 family
OOOKNECK_03370 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OOOKNECK_03371 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
OOOKNECK_03372 7.1e-250 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
OOOKNECK_03373 8.2e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
OOOKNECK_03374 1.7e-16 ytxH S COG4980 Gas vesicle protein
OOOKNECK_03375 2.2e-43 ytxJ O Protein of unknown function (DUF2847)
OOOKNECK_03376 1.6e-194 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
OOOKNECK_03377 3.9e-179 ccpA K catabolite control protein A
OOOKNECK_03378 4.8e-143 motA N flagellar motor
OOOKNECK_03379 2.7e-98 motS N Flagellar motor protein
OOOKNECK_03380 9.3e-225 acuC BQ histone deacetylase
OOOKNECK_03381 3.9e-108 acuB S Domain in cystathionine beta-synthase and other proteins.
OOOKNECK_03382 7.5e-120 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
OOOKNECK_03383 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OOOKNECK_03384 4.7e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OOOKNECK_03385 7.4e-47 azlD S Branched-chain amino acid transport protein (AzlD)
OOOKNECK_03386 1.9e-119 azlC E AzlC protein
OOOKNECK_03387 5.4e-147 K Transcriptional regulator
OOOKNECK_03388 5.8e-147 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OOOKNECK_03389 2.9e-126 E GDSL-like Lipase/Acylhydrolase family
OOOKNECK_03391 1.3e-08 yhbO 1.11.1.6, 3.5.1.124 S protease
OOOKNECK_03393 5.8e-214 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OOOKNECK_03394 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OOOKNECK_03395 4.6e-268 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
OOOKNECK_03396 8.6e-84 ytsP 1.8.4.14 T GAF domain-containing protein
OOOKNECK_03397 7.9e-106 yttP K Transcriptional regulator
OOOKNECK_03398 4.3e-144 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
OOOKNECK_03399 2.3e-261 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
OOOKNECK_03400 6.4e-238 braB E Component of the transport system for branched-chain amino acids
OOOKNECK_03401 2.1e-22 iscS2 2.8.1.7 E Cysteine desulfurase
OOOKNECK_03402 7.7e-172 iscS2 2.8.1.7 E Cysteine desulfurase
OOOKNECK_03403 1.4e-220 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OOOKNECK_03404 6.6e-31 sspB S spore protein
OOOKNECK_03405 9.1e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
OOOKNECK_03406 8.3e-301 ytcJ S amidohydrolase
OOOKNECK_03407 5.9e-149 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OOOKNECK_03408 1.4e-176 sppA OU signal peptide peptidase SppA
OOOKNECK_03409 4.5e-80 yteJ S RDD family
OOOKNECK_03410 4.1e-111 ytfI S Protein of unknown function (DUF2953)
OOOKNECK_03411 1.5e-63 ytfJ S Sporulation protein YtfJ
OOOKNECK_03412 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OOOKNECK_03413 9.7e-175 ytxK 2.1.1.72 L DNA methylase
OOOKNECK_03414 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OOOKNECK_03415 8e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
OOOKNECK_03416 4.3e-233 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
OOOKNECK_03417 6.1e-260 argH 4.3.2.1 E argininosuccinate lyase
OOOKNECK_03419 3.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
OOOKNECK_03420 1.1e-127 ytkL S Belongs to the UPF0173 family
OOOKNECK_03421 6.8e-238 ytoI K transcriptional regulator containing CBS domains
OOOKNECK_03422 3.8e-45 ytpI S YtpI-like protein
OOOKNECK_03423 2.9e-176 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
OOOKNECK_03424 6.4e-22
OOOKNECK_03425 5.6e-86 ytrI
OOOKNECK_03426 2.5e-53 ytrH S Sporulation protein YtrH
OOOKNECK_03427 0.0 dnaE 2.7.7.7 L DNA polymerase
OOOKNECK_03428 5.9e-222 ytsJ 1.1.1.38 C Malate dehydrogenase
OOOKNECK_03429 6e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OOOKNECK_03430 2.4e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
OOOKNECK_03431 9.8e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
OOOKNECK_03432 1.2e-292 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
OOOKNECK_03433 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
OOOKNECK_03434 1.8e-193 ytvI S sporulation integral membrane protein YtvI
OOOKNECK_03435 1.5e-72 yeaL S membrane
OOOKNECK_03436 8.1e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
OOOKNECK_03437 2e-241 icd 1.1.1.42 C isocitrate
OOOKNECK_03438 3.6e-171 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
OOOKNECK_03439 5e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_03440 2.6e-308 phoR 2.7.13.3 T Signal transduction histidine kinase
OOOKNECK_03441 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OOOKNECK_03442 2.7e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
OOOKNECK_03443 2.6e-104 ytaF P Probably functions as a manganese efflux pump
OOOKNECK_03444 3.9e-94 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
OOOKNECK_03445 1.5e-155 ytbE S reductase
OOOKNECK_03446 6.9e-199 ytbD EGP Major facilitator Superfamily
OOOKNECK_03447 1.6e-64 ytcD K Transcriptional regulator
OOOKNECK_03448 1.3e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
OOOKNECK_03449 1.5e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OOOKNECK_03450 4.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OOOKNECK_03451 7.7e-250 dnaB L Membrane attachment protein
OOOKNECK_03452 2.9e-168 dnaI L Primosomal protein DnaI
OOOKNECK_03453 1.8e-105 ytxB S SNARE associated Golgi protein
OOOKNECK_03454 1.6e-149 ytxC S YtxC-like family
OOOKNECK_03455 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OOOKNECK_03456 4.1e-147 ysaA S HAD-hyrolase-like
OOOKNECK_03457 0.0 lytS 2.7.13.3 T Histidine kinase
OOOKNECK_03458 1e-128 lytT T COG3279 Response regulator of the LytR AlgR family
OOOKNECK_03459 3.6e-36 lrgA S effector of murein hydrolase LrgA
OOOKNECK_03460 2.7e-107 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
OOOKNECK_03461 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OOOKNECK_03462 3.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
OOOKNECK_03463 2.7e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OOOKNECK_03464 1e-38 ysdA S Membrane
OOOKNECK_03465 2.6e-62 ysdB S Sigma-w pathway protein YsdB
OOOKNECK_03466 4e-206 ysdC G COG1363 Cellulase M and related proteins
OOOKNECK_03467 1e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
OOOKNECK_03468 1.5e-291 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
OOOKNECK_03469 2.8e-307 araB 2.7.1.16 C Belongs to the ribulokinase family
OOOKNECK_03470 1.6e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
OOOKNECK_03471 4e-137 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
OOOKNECK_03472 7e-212 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
OOOKNECK_03473 6.6e-232 araN G carbohydrate transport
OOOKNECK_03474 9.6e-164 araP P PFAM binding-protein-dependent transport systems inner membrane component
OOOKNECK_03475 5.1e-140 araQ G transport system permease
OOOKNECK_03476 4.4e-296 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
OOOKNECK_03477 0.0 cstA T Carbon starvation protein
OOOKNECK_03478 1.4e-245 glcF C Glycolate oxidase
OOOKNECK_03479 1.1e-251 glcD 1.1.3.15 C FAD binding domain
OOOKNECK_03480 8.2e-191 ysfB KT regulator
OOOKNECK_03481 7.6e-32 sspI S Belongs to the SspI family
OOOKNECK_03482 1e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOOKNECK_03483 4e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OOOKNECK_03484 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
OOOKNECK_03485 1.5e-164 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OOOKNECK_03486 2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OOOKNECK_03487 2.3e-82 cvpA S membrane protein, required for colicin V production
OOOKNECK_03488 4.9e-92 polX L COG1796 DNA polymerase IV (family X)
OOOKNECK_03489 1.4e-181 polX L COG1796 DNA polymerase IV (family X)
OOOKNECK_03490 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
OOOKNECK_03491 4.7e-67 yshE S membrane
OOOKNECK_03492 5.4e-116 ywbB S Protein of unknown function (DUF2711)
OOOKNECK_03493 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
OOOKNECK_03494 2.7e-103 fadR K Transcriptional regulator
OOOKNECK_03495 3.6e-132 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
OOOKNECK_03496 2.2e-137 etfB C Electron transfer flavoprotein
OOOKNECK_03497 3e-176 etfA C Electron transfer flavoprotein
OOOKNECK_03498 8.9e-297 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
OOOKNECK_03499 2.5e-52 trxA O Belongs to the thioredoxin family
OOOKNECK_03500 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
OOOKNECK_03501 1.2e-211 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
OOOKNECK_03502 3.5e-79 yslB S Protein of unknown function (DUF2507)
OOOKNECK_03503 4.8e-108 sdhC C succinate dehydrogenase
OOOKNECK_03504 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OOOKNECK_03505 3.9e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
OOOKNECK_03506 2.1e-73 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
OOOKNECK_03507 1.5e-17 gerE K Transcriptional regulator
OOOKNECK_03508 1.3e-47 yqaB E IrrE N-terminal-like domain
OOOKNECK_03509 2.5e-75 S Bacterial PH domain
OOOKNECK_03510 3.6e-88 yokF 3.1.31.1 L RNA catabolic process
OOOKNECK_03511 2.9e-26 K sequence-specific DNA binding
OOOKNECK_03512 2.7e-19 yqaF K Helix-turn-helix XRE-family like proteins
OOOKNECK_03517 8.2e-35 K Phage regulatory protein Rha (Phage_pRha)
OOOKNECK_03518 6.6e-75
OOOKNECK_03521 1.7e-20 J translation initiation factor activity
OOOKNECK_03523 2.4e-154 yqaJ L YqaJ-like viral recombinase domain
OOOKNECK_03524 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
OOOKNECK_03525 3.2e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
OOOKNECK_03526 4.9e-143 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
OOOKNECK_03527 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
OOOKNECK_03528 1.6e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
OOOKNECK_03529 5.2e-157 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
OOOKNECK_03530 4e-155 S Fusaric acid resistance protein-like
OOOKNECK_03531 6.5e-19
OOOKNECK_03532 6.2e-290 3.6.4.12 L AAA domain
OOOKNECK_03533 0.0 L AAA ATPase domain
OOOKNECK_03534 2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OOOKNECK_03535 7.9e-08 S YyzF-like protein
OOOKNECK_03538 2.3e-207 yycP
OOOKNECK_03539 1.9e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
OOOKNECK_03540 9.3e-178 C oxidoreductases (related to aryl-alcohol dehydrogenases)
OOOKNECK_03541 1.4e-81 yycN 2.3.1.128 K Acetyltransferase
OOOKNECK_03543 2.1e-197 S Histidine kinase
OOOKNECK_03544 8.2e-165 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
OOOKNECK_03545 1.5e-253 rocE E amino acid
OOOKNECK_03546 8.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OOOKNECK_03547 1.6e-61 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
OOOKNECK_03548 1.3e-42 sdpR K transcriptional
OOOKNECK_03549 4.7e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
OOOKNECK_03550 8.4e-197 S Major Facilitator Superfamily
OOOKNECK_03551 3.7e-244 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
OOOKNECK_03552 6.5e-93 K PFAM response regulator receiver
OOOKNECK_03553 1.9e-63 S Peptidase propeptide and YPEB domain
OOOKNECK_03554 1.7e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OOOKNECK_03555 6.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
OOOKNECK_03556 8.6e-148 yycI S protein conserved in bacteria
OOOKNECK_03557 2.2e-257 yycH S protein conserved in bacteria
OOOKNECK_03558 0.0 vicK 2.7.13.3 T Histidine kinase
OOOKNECK_03559 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
OOOKNECK_03564 1.1e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OOOKNECK_03565 2.5e-71 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_03566 6.1e-252 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
OOOKNECK_03567 2.3e-27 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
OOOKNECK_03569 3.5e-17 yycC K YycC-like protein
OOOKNECK_03570 2.1e-214 M Glycosyltransferase Family 4
OOOKNECK_03571 5.5e-192 S Ecdysteroid kinase
OOOKNECK_03572 2.1e-232 S Carbamoyl-phosphate synthase L chain, ATP binding domain
OOOKNECK_03573 7.8e-220 M Glycosyltransferase Family 4
OOOKNECK_03574 1.3e-119 S GlcNAc-PI de-N-acetylase
OOOKNECK_03575 6.8e-83 KLT COG0515 Serine threonine protein kinase
OOOKNECK_03576 3.2e-72 rplI J binds to the 23S rRNA
OOOKNECK_03577 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
OOOKNECK_03578 1e-149 yybS S membrane
OOOKNECK_03580 1.3e-79 cotF M Spore coat protein
OOOKNECK_03581 2e-64 ydeP3 K Transcriptional regulator
OOOKNECK_03582 7.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
OOOKNECK_03583 2.5e-150 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
OOOKNECK_03584 2e-266 sacB 2.4.1.10 GH68 M levansucrase activity
OOOKNECK_03585 1.5e-302 levB 3.2.1.26, 3.2.1.64, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
OOOKNECK_03586 1.1e-108 K FCD domain
OOOKNECK_03587 1.9e-73 dinB S PFAM DinB family protein
OOOKNECK_03588 8.9e-146 G Major Facilitator Superfamily
OOOKNECK_03589 4.2e-54 ypaA S Protein of unknown function (DUF1304)
OOOKNECK_03590 4.4e-112 drgA C nitroreductase
OOOKNECK_03591 1.6e-65 ydgJ K Winged helix DNA-binding domain
OOOKNECK_03592 5.3e-148 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
OOOKNECK_03593 3.1e-75 yybA 2.3.1.57 K transcriptional
OOOKNECK_03594 1.8e-70 yjcF S Acetyltransferase (GNAT) domain
OOOKNECK_03595 3.3e-19 cadC3 K transcriptional
OOOKNECK_03596 3.8e-103 S Alpha/beta hydrolase family
OOOKNECK_03597 2e-27
OOOKNECK_03598 2.8e-67 ynaF
OOOKNECK_03599 1.1e-167 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OOOKNECK_03600 1.6e-213 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
OOOKNECK_03601 7.5e-150 yyaK S CAAX protease self-immunity
OOOKNECK_03602 3.5e-236 ydjK G Sugar (and other) transporter
OOOKNECK_03603 5.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
OOOKNECK_03604 6.9e-170 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
OOOKNECK_03605 1.7e-139 xth 3.1.11.2 L exodeoxyribonuclease III
OOOKNECK_03606 4.5e-86 adaB 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OOOKNECK_03607 1.2e-95 adaA 3.2.2.21 K Transcriptional regulator
OOOKNECK_03608 3e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OOOKNECK_03609 8.4e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
OOOKNECK_03610 3.6e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
OOOKNECK_03611 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
OOOKNECK_03612 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
OOOKNECK_03613 2.3e-33 yyzM S protein conserved in bacteria
OOOKNECK_03614 2.4e-168 yyaD S Membrane
OOOKNECK_03615 4.5e-57 4.2.1.103 K FR47-like protein
OOOKNECK_03616 1.1e-107 yyaC S Sporulation protein YyaC
OOOKNECK_03617 1.5e-147 spo0J K Belongs to the ParB family
OOOKNECK_03618 2.7e-135 soj D COG1192 ATPases involved in chromosome partitioning
OOOKNECK_03619 1.1e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
OOOKNECK_03620 1.5e-124 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
OOOKNECK_03621 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
OOOKNECK_03622 5.2e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OOOKNECK_03623 8.2e-106 jag S single-stranded nucleic acid binding R3H
OOOKNECK_03624 4.3e-133 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
OOOKNECK_03625 1.2e-50 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
OOOKNECK_03626 4.3e-250 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OOOKNECK_03627 8e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
OOOKNECK_03628 2.4e-33 yaaA S S4 domain
OOOKNECK_03629 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OOOKNECK_03630 8.1e-38 yaaB S Domain of unknown function (DUF370)
OOOKNECK_03631 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OOOKNECK_03632 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
OOOKNECK_03633 1.2e-127 pdaB 3.5.1.104 G Polysaccharide deacetylase
OOOKNECK_03634 1.7e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
OOOKNECK_03635 1.7e-75 gerD
OOOKNECK_03636 2.5e-192 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
OOOKNECK_03637 2.4e-130 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
OOOKNECK_03638 3.6e-76 ybaK S Protein of unknown function (DUF2521)
OOOKNECK_03639 2.7e-140 ybaJ Q Methyltransferase domain
OOOKNECK_03640 1.6e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
OOOKNECK_03641 7.1e-77 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OOOKNECK_03642 5.9e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
OOOKNECK_03643 1.9e-136 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOOKNECK_03644 1.2e-144 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOOKNECK_03645 1.4e-153 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
OOOKNECK_03646 4.7e-58 rplQ J Ribosomal protein L17
OOOKNECK_03647 2.4e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOOKNECK_03648 2.8e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OOOKNECK_03649 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OOOKNECK_03650 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
OOOKNECK_03651 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OOOKNECK_03652 2.6e-140 map 3.4.11.18 E Methionine aminopeptidase
OOOKNECK_03653 9.8e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
OOOKNECK_03654 3.3e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
OOOKNECK_03655 4.1e-72 rplO J binds to the 23S rRNA
OOOKNECK_03656 1.9e-23 rpmD J Ribosomal protein L30
OOOKNECK_03657 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OOOKNECK_03658 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OOOKNECK_03659 1.5e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OOOKNECK_03660 2.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OOOKNECK_03661 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OOOKNECK_03662 3.9e-93 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OOOKNECK_03663 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OOOKNECK_03664 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OOOKNECK_03665 1.8e-38 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OOOKNECK_03666 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
OOOKNECK_03667 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OOOKNECK_03668 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OOOKNECK_03669 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OOOKNECK_03670 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OOOKNECK_03671 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OOOKNECK_03672 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
OOOKNECK_03673 2.3e-105 rplD J Forms part of the polypeptide exit tunnel
OOOKNECK_03674 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OOOKNECK_03675 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
OOOKNECK_03676 2.6e-172 ybaC 3.4.11.5 S Alpha/beta hydrolase family
OOOKNECK_03677 1.8e-223 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OOOKNECK_03678 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OOOKNECK_03679 7.9e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
OOOKNECK_03680 6.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OOOKNECK_03681 2.7e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
OOOKNECK_03682 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOOKNECK_03683 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OOOKNECK_03684 4.8e-108 rsmC 2.1.1.172 J Methyltransferase
OOOKNECK_03685 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
OOOKNECK_03686 1.9e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OOOKNECK_03687 2.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
OOOKNECK_03688 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OOOKNECK_03689 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
OOOKNECK_03690 7.8e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
OOOKNECK_03691 4.4e-115 sigH K Belongs to the sigma-70 factor family
OOOKNECK_03692 1.8e-87 yacP S RNA-binding protein containing a PIN domain
OOOKNECK_03693 1.8e-133 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OOOKNECK_03694 1.7e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
OOOKNECK_03695 1.1e-267 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
OOOKNECK_03696 1.6e-117 cysE 2.3.1.30 E Serine acetyltransferase
OOOKNECK_03697 4.2e-275 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OOOKNECK_03698 3.5e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
OOOKNECK_03699 1.8e-122 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
OOOKNECK_03700 5.2e-185 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
OOOKNECK_03701 4.2e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
OOOKNECK_03702 3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OOOKNECK_03703 0.0 clpC O Belongs to the ClpA ClpB family
OOOKNECK_03704 2.7e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
OOOKNECK_03705 1.1e-60 mcsA 2.7.14.1 S protein with conserved CXXC pairs
OOOKNECK_03706 7.5e-77 ctsR K Belongs to the CtsR family
OOOKNECK_03707 1.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
OOOKNECK_03708 1.6e-180 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OOOKNECK_03709 7.1e-28 yazB K transcriptional
OOOKNECK_03710 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OOOKNECK_03711 2.6e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OOOKNECK_03712 9.1e-153 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OOOKNECK_03713 1.6e-149 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
OOOKNECK_03714 5.7e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
OOOKNECK_03715 1.2e-263 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OOOKNECK_03716 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
OOOKNECK_03717 2.6e-150 yacD 5.2.1.8 O peptidyl-prolyl isomerase
OOOKNECK_03718 1.2e-160 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OOOKNECK_03719 2.4e-144 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
OOOKNECK_03720 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OOOKNECK_03721 2.5e-92 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
OOOKNECK_03722 2.1e-263 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
OOOKNECK_03723 9.2e-181 KLT serine threonine protein kinase
OOOKNECK_03724 1.2e-121 yabS S protein containing a von Willebrand factor type A (vWA) domain
OOOKNECK_03725 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
OOOKNECK_03728 1.1e-57 yabR J RNA binding protein (contains ribosomal protein S1 domain)
OOOKNECK_03729 9.2e-57 divIC D Septum formation initiator
OOOKNECK_03730 8.7e-100 yabQ S spore cortex biosynthesis protein
OOOKNECK_03731 1.9e-49 yabP S Sporulation protein YabP
OOOKNECK_03732 5.6e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
OOOKNECK_03733 7e-270 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
OOOKNECK_03734 5.8e-270 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
OOOKNECK_03735 2.6e-89 spoVT K stage V sporulation protein
OOOKNECK_03736 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OOOKNECK_03737 1.1e-193 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OOOKNECK_03738 6.9e-39 yabK S Peptide ABC transporter permease
OOOKNECK_03739 1.2e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
OOOKNECK_03740 2.8e-103 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OOOKNECK_03741 2.7e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OOOKNECK_03742 1.7e-246 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OOOKNECK_03743 1.8e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
OOOKNECK_03744 5.1e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
OOOKNECK_03745 2.9e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
OOOKNECK_03746 7.8e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OOOKNECK_03747 2.9e-27 sspF S DNA topological change
OOOKNECK_03748 4.1e-124 yabG S peptidase
OOOKNECK_03749 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
OOOKNECK_03750 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
OOOKNECK_03751 4e-216 rpfB GH23 T protein conserved in bacteria
OOOKNECK_03752 2.2e-142 tatD L hydrolase, TatD
OOOKNECK_03753 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OOOKNECK_03754 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
OOOKNECK_03755 2.8e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OOOKNECK_03756 5.2e-47 yazA L endonuclease containing a URI domain
OOOKNECK_03757 1.6e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
OOOKNECK_03758 5e-36 yabA L Involved in initiation control of chromosome replication
OOOKNECK_03759 1.1e-144 yaaT S stage 0 sporulation protein
OOOKNECK_03760 1.6e-174 holB 2.7.7.7 L DNA polymerase III
OOOKNECK_03761 3.8e-70 yaaR S protein conserved in bacteria
OOOKNECK_03762 7.5e-55 yaaQ S protein conserved in bacteria
OOOKNECK_03763 7.8e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OOOKNECK_03764 1.9e-256 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
OOOKNECK_03765 2.6e-176 yaaN P Belongs to the TelA family
OOOKNECK_03766 1.1e-99 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
OOOKNECK_03767 4.2e-29 csfB S Inhibitor of sigma-G Gin
OOOKNECK_03768 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
OOOKNECK_03770 1.2e-07 S Hypothetical protein Yqai
OOOKNECK_03772 4.2e-85
OOOKNECK_03773 4.3e-61 S DNA binding
OOOKNECK_03774 2.9e-32
OOOKNECK_03775 1.5e-12 K Helix-turn-helix XRE-family like proteins
OOOKNECK_03776 7.9e-16 K Helix-turn-helix XRE-family like proteins
OOOKNECK_03777 1.3e-48
OOOKNECK_03778 1.7e-25 S Protein of unknown function (DUF4064)
OOOKNECK_03779 2.4e-30 yqaB E IrrE N-terminal-like domain
OOOKNECK_03780 2.3e-77 S Phage integrase family
OOOKNECK_03781 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
OOOKNECK_03782 6.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OOOKNECK_03783 5.3e-125 ydiL S CAAX protease self-immunity
OOOKNECK_03784 1.7e-27 ydiK S Domain of unknown function (DUF4305)
OOOKNECK_03785 1.2e-121 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OOOKNECK_03786 1.7e-18 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
OOOKNECK_03787 4.4e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
OOOKNECK_03788 1.2e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
OOOKNECK_03789 4e-310 ydiF S ABC transporter
OOOKNECK_03790 8.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OOOKNECK_03791 9e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
OOOKNECK_03792 5.1e-122 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
OOOKNECK_03793 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
OOOKNECK_03794 4.1e-173 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OOOKNECK_03796 1.5e-175 yaaC S YaaC-like Protein
OOOKNECK_03797 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
OOOKNECK_03798 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
OOOKNECK_03799 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
OOOKNECK_03800 4.7e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
OOOKNECK_03801 1.1e-202 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OOOKNECK_03802 2.3e-196 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
OOOKNECK_03803 1.3e-09
OOOKNECK_03804 6.6e-119 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
OOOKNECK_03805 1.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
OOOKNECK_03806 3.9e-208 yaaH M Glycoside Hydrolase Family
OOOKNECK_03807 6.6e-96 yaaI Q COG1335 Amidases related to nicotinamidase
OOOKNECK_03808 9.5e-83 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
OOOKNECK_03809 2.3e-311 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OOOKNECK_03810 1e-35 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OOOKNECK_03811 2.3e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OOOKNECK_03812 3.6e-32 yaaL S Protein of unknown function (DUF2508)
OOOKNECK_03813 4.8e-36 bofA S Sigma-K factor-processing regulatory protein BofA
OOOKNECK_03814 0.0 L Transposase and inactivated derivatives, TnpA family
OOOKNECK_03815 7.1e-85 L resolvase
OOOKNECK_03816 1.3e-78
OOOKNECK_03818 6e-26 S Protein of unknown function (DUF1657)
OOOKNECK_03819 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
OOOKNECK_03820 2.6e-80 spoVAC S stage V sporulation protein AC
OOOKNECK_03821 1e-195 spoVAD I Stage V sporulation protein AD
OOOKNECK_03822 8.5e-57 spoVAE S stage V sporulation protein
OOOKNECK_03823 5.8e-29 S Protein of unknown function (DUF1657)
OOOKNECK_03824 4.7e-149 yetF1 S membrane
OOOKNECK_03825 1.2e-70 S Protein of unknown function (DUF421)
OOOKNECK_03826 2.7e-285 clsA_1 I PLD-like domain
OOOKNECK_03827 2.5e-92 S Protein of unknown function (DUF421)
OOOKNECK_03828 2.7e-67 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOOKNECK_03829 5.3e-19 V VanZ like family
OOOKNECK_03831 3.2e-45
OOOKNECK_03836 5.6e-07 S YopX protein
OOOKNECK_03839 1.7e-45 S dUTPase
OOOKNECK_03840 2.7e-167 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
OOOKNECK_03843 5e-17 yqaO S Phage-like element PBSX protein XtrA
OOOKNECK_03845 3e-54 S Protein of unknown function (DUF1064)
OOOKNECK_03846 1.8e-11 S YopX protein
OOOKNECK_03848 2.5e-135 xkdC L IstB-like ATP binding protein
OOOKNECK_03849 4.1e-13 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
OOOKNECK_03851 5.8e-47
OOOKNECK_03853 2.2e-10 FG Mazg nucleotide pyrophosphohydrolase
OOOKNECK_03854 5.9e-07 S YopX protein
OOOKNECK_03855 2.2e-62 S dUTPase
OOOKNECK_03856 2.4e-206 L COG3385 FOG Transposase and inactivated derivatives
OOOKNECK_03858 5.8e-58 L COG3385 FOG Transposase and inactivated derivatives
OOOKNECK_03859 1.9e-125 S Uncharacterised protein family (UPF0236)
OOOKNECK_03860 2.6e-154 L Transposase DDE domain group 1
OOOKNECK_03862 3.9e-12 K Transcriptional regulator
OOOKNECK_03864 2.1e-77 L COG3385 FOG Transposase and inactivated derivatives
OOOKNECK_03865 4.9e-122 L COG3385 FOG Transposase and inactivated derivatives
OOOKNECK_03866 2.2e-38 S COG NOG14552 non supervised orthologous group
OOOKNECK_03867 1.2e-63 ndh 1.6.99.3 C NADH dehydrogenase
OOOKNECK_03868 1.6e-79 ndh 1.6.99.3 C NADH dehydrogenase
OOOKNECK_03869 1.5e-52 ndh 1.6.99.3 C NADH dehydrogenase
OOOKNECK_03870 5.5e-64 L HTH-like domain
OOOKNECK_03871 9.9e-209 L PFAM transposase IS116 IS110 IS902 family
OOOKNECK_03876 2e-08
OOOKNECK_03879 1.3e-07
OOOKNECK_03881 2.4e-43 L PFAM Transposase, IS4-like
OOOKNECK_03882 1.8e-21 recT L RecT family
OOOKNECK_03883 1.5e-20 recT L RecT family
OOOKNECK_03884 6.6e-46 opuAA 3.6.3.32 E glycine betaine
OOOKNECK_03885 5.7e-62 opuAA 3.6.3.32 E glycine betaine
OOOKNECK_03886 9.6e-37 opuAA 3.6.3.32 E glycine betaine
OOOKNECK_03887 3.3e-148 L COG3385 FOG Transposase and inactivated derivatives
OOOKNECK_03890 1.6e-08
OOOKNECK_03893 3.9e-07 S Virus attachment protein p12 family
OOOKNECK_03894 2.7e-106 feoB P transporter of a GTP-driven Fe(2 ) uptake system
OOOKNECK_03895 5e-62 S Domain of unknown function (DUF4275)
OOOKNECK_03896 1.3e-23 S Cysteine-rich CPCC
OOOKNECK_03897 1.7e-95 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
OOOKNECK_03898 5e-79 niaR S small molecule binding protein (contains 3H domain)
OOOKNECK_03899 2.7e-70 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OOOKNECK_03900 2.4e-110 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OOOKNECK_03901 1.2e-54 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
OOOKNECK_03902 2e-28 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
OOOKNECK_03903 1e-24 yfjT
OOOKNECK_03904 4.3e-08 S gas vesicle protein
OOOKNECK_03905 4.3e-19 L PFAM transposase IS4 family protein
OOOKNECK_03906 5.4e-75 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
OOOKNECK_03907 5.8e-79 S COG0457 FOG TPR repeat
OOOKNECK_03908 1.5e-54 T PhoQ Sensor
OOOKNECK_03909 6.6e-79 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OOOKNECK_03910 9.2e-66 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
OOOKNECK_03911 2.5e-77 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
OOOKNECK_03912 3.4e-27 yvbK 3.1.3.25 K acetyltransferase
OOOKNECK_03913 1.6e-57 dcuR T COG4565 Response regulator of citrate malate metabolism
OOOKNECK_03914 6.1e-95 sfcA 1.1.1.38 C Malate dehydrogenase
OOOKNECK_03915 2e-101 glcT K antiterminator
OOOKNECK_03916 3.7e-39 S von Willebrand factor type A domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)