ORF_ID e_value Gene_name EC_number CAZy COGs Description
KFCOGGID_00001 2.5e-75
KFCOGGID_00002 1.2e-146 S von Willebrand factor (vWF) type A domain
KFCOGGID_00003 5.8e-189 S von Willebrand factor (vWF) type A domain
KFCOGGID_00004 5.4e-93
KFCOGGID_00005 2.7e-177 S Protein of unknown function DUF58
KFCOGGID_00006 1e-196 moxR S ATPase family associated with various cellular activities (AAA)
KFCOGGID_00007 4.2e-144 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFCOGGID_00008 4.9e-70 S LytR cell envelope-related transcriptional attenuator
KFCOGGID_00009 2.4e-43 cspA K 'Cold-shock' DNA-binding domain
KFCOGGID_00010 2.7e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KFCOGGID_00011 1.7e-10 S Proteins of 100 residues with WXG
KFCOGGID_00012 8.7e-57
KFCOGGID_00013 1.1e-98
KFCOGGID_00014 1.8e-133 KT Response regulator receiver domain protein
KFCOGGID_00015 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KFCOGGID_00016 1e-66 cspB K 'Cold-shock' DNA-binding domain
KFCOGGID_00017 4.7e-191 S Protein of unknown function (DUF3027)
KFCOGGID_00018 4.7e-185 uspA T Belongs to the universal stress protein A family
KFCOGGID_00019 0.0 clpC O ATPase family associated with various cellular activities (AAA)
KFCOGGID_00023 2.8e-211 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
KFCOGGID_00025 5.1e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
KFCOGGID_00026 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFCOGGID_00027 6e-74 K helix_turn_helix, Lux Regulon
KFCOGGID_00028 1.5e-85 S Aminoacyl-tRNA editing domain
KFCOGGID_00029 3.9e-139 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
KFCOGGID_00030 6.7e-34 gluB ET Belongs to the bacterial solute-binding protein 3 family
KFCOGGID_00031 2.9e-99 gluB ET Belongs to the bacterial solute-binding protein 3 family
KFCOGGID_00032 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
KFCOGGID_00033 4.8e-199 gluD E Binding-protein-dependent transport system inner membrane component
KFCOGGID_00034 1.9e-192 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
KFCOGGID_00035 0.0 L DEAD DEAH box helicase
KFCOGGID_00036 3.2e-256 rarA L Recombination factor protein RarA
KFCOGGID_00038 5.7e-256 EGP Major facilitator Superfamily
KFCOGGID_00039 0.0 ecfA GP ABC transporter, ATP-binding protein
KFCOGGID_00040 9.6e-104 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KFCOGGID_00042 1.7e-139 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
KFCOGGID_00043 1.7e-212 E Aminotransferase class I and II
KFCOGGID_00044 4.9e-137 bioM P ATPases associated with a variety of cellular activities
KFCOGGID_00045 1.6e-73 2.8.2.22 S Arylsulfotransferase Ig-like domain
KFCOGGID_00046 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFCOGGID_00047 0.0 S Tetratricopeptide repeat
KFCOGGID_00048 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFCOGGID_00049 5.7e-211 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KFCOGGID_00050 2e-160 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_00053 4.2e-19
KFCOGGID_00055 3.3e-18
KFCOGGID_00056 1.8e-286 glnA 6.3.1.2 E glutamine synthetase
KFCOGGID_00057 9.4e-144 S Domain of unknown function (DUF4191)
KFCOGGID_00058 5.4e-278 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFCOGGID_00059 1.2e-103 S Protein of unknown function (DUF3043)
KFCOGGID_00060 1.2e-258 argE E Peptidase dimerisation domain
KFCOGGID_00061 3.7e-191 V N-Acetylmuramoyl-L-alanine amidase
KFCOGGID_00062 1.9e-152 ytrE V ATPases associated with a variety of cellular activities
KFCOGGID_00063 3.2e-195
KFCOGGID_00064 2.6e-228 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
KFCOGGID_00065 0.0 S Uncharacterised protein family (UPF0182)
KFCOGGID_00066 4e-195 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KFCOGGID_00067 0.0 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KFCOGGID_00068 9.2e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
KFCOGGID_00070 4.1e-130 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KFCOGGID_00071 1.5e-146 GM GDP-mannose 4,6 dehydratase
KFCOGGID_00072 3.6e-151 GM ABC-2 type transporter
KFCOGGID_00073 4.9e-145 tagH 3.6.3.38, 3.6.3.40 GM ABC transporter
KFCOGGID_00074 5.1e-96 2.3.1.183 M Acetyltransferase (GNAT) domain
KFCOGGID_00075 7.6e-114 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KFCOGGID_00076 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFCOGGID_00077 5.9e-296 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH chorismate binding enzyme
KFCOGGID_00078 6.4e-153 pabC 2.6.1.42, 2.6.1.85, 4.1.3.38 E branched-chain-amino-acid transaminase activity
KFCOGGID_00079 6.9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KFCOGGID_00080 2.5e-101 divIC D Septum formation initiator
KFCOGGID_00081 1.4e-87 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
KFCOGGID_00082 1.2e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KFCOGGID_00084 1.8e-96
KFCOGGID_00085 8.8e-281 sdaA 4.3.1.17 E Serine dehydratase alpha chain
KFCOGGID_00086 1.3e-72 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
KFCOGGID_00087 3.1e-58 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KFCOGGID_00089 7.5e-142 yplQ S Haemolysin-III related
KFCOGGID_00090 2.7e-285 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KFCOGGID_00091 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KFCOGGID_00092 0.0 D FtsK/SpoIIIE family
KFCOGGID_00093 5.4e-270 K Cell envelope-related transcriptional attenuator domain
KFCOGGID_00094 5.8e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
KFCOGGID_00095 0.0 S Glycosyl transferase, family 2
KFCOGGID_00096 7e-265
KFCOGGID_00097 6.3e-66 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
KFCOGGID_00098 1.1e-71 cof 5.2.1.8 T Eukaryotic phosphomannomutase
KFCOGGID_00099 3.7e-131 ctsW S Phosphoribosyl transferase domain
KFCOGGID_00100 2.3e-62 rulA 3.4.21.88 KT Peptidase S24-like
KFCOGGID_00101 1.9e-203 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KFCOGGID_00102 1.9e-127 T Response regulator receiver domain protein
KFCOGGID_00103 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFCOGGID_00104 5.1e-102 carD K CarD-like/TRCF domain
KFCOGGID_00105 8.5e-84 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KFCOGGID_00106 4.3e-139 znuB U ABC 3 transport family
KFCOGGID_00107 5.3e-164 znuC P ATPases associated with a variety of cellular activities
KFCOGGID_00108 1e-161 P Zinc-uptake complex component A periplasmic
KFCOGGID_00109 2e-163 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFCOGGID_00110 3.6e-242 rpsA J Ribosomal protein S1
KFCOGGID_00111 2.7e-106 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KFCOGGID_00112 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KFCOGGID_00113 1.7e-179 terC P Integral membrane protein, TerC family
KFCOGGID_00114 6.6e-273 pyk 2.7.1.40 G Pyruvate kinase
KFCOGGID_00115 1.8e-110 aspA 3.6.1.13 L NUDIX domain
KFCOGGID_00117 9.2e-120 pdtaR T Response regulator receiver domain protein
KFCOGGID_00118 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFCOGGID_00119 1.9e-172 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
KFCOGGID_00120 2.4e-119 3.6.1.13 L NUDIX domain
KFCOGGID_00121 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KFCOGGID_00122 2.3e-218 ykiI
KFCOGGID_00124 1.1e-34 L Phage integrase family
KFCOGGID_00125 3.1e-87 L Phage integrase family
KFCOGGID_00126 9e-110 3.4.13.21 E Peptidase family S51
KFCOGGID_00127 6e-274 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KFCOGGID_00128 9.8e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFCOGGID_00129 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
KFCOGGID_00130 8.9e-89 L Transposase
KFCOGGID_00131 4.5e-85
KFCOGGID_00132 9.9e-112 bepIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
KFCOGGID_00133 2.2e-105 L transposase activity
KFCOGGID_00134 7.3e-101 L PFAM Integrase catalytic
KFCOGGID_00135 2.3e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KFCOGGID_00136 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
KFCOGGID_00137 3.4e-189 pit P Phosphate transporter family
KFCOGGID_00138 1.1e-115 MA20_27875 P Protein of unknown function DUF47
KFCOGGID_00139 8.2e-120 K helix_turn_helix, Lux Regulon
KFCOGGID_00140 2.1e-233 T Histidine kinase
KFCOGGID_00141 1.1e-19 pacL 3.6.3.8, 3.6.3.9 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KFCOGGID_00142 2.7e-185 V ATPases associated with a variety of cellular activities
KFCOGGID_00143 2e-225 V ABC-2 family transporter protein
KFCOGGID_00144 3.4e-253 V ABC-2 family transporter protein
KFCOGGID_00145 2e-285 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KFCOGGID_00146 1.5e-194 L Transposase and inactivated derivatives IS30 family
KFCOGGID_00148 8.8e-91
KFCOGGID_00149 1.3e-63 D MobA/MobL family
KFCOGGID_00150 2.8e-46 L Transposase
KFCOGGID_00151 2.6e-122 tnp7109-21 L Integrase core domain
KFCOGGID_00152 1.1e-26 2.1.1.72 S Adenine-specific methyltransferase EcoRI
KFCOGGID_00153 9e-40
KFCOGGID_00154 3.6e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
KFCOGGID_00156 6.8e-46 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KFCOGGID_00158 2.4e-240 pbuX F Permease family
KFCOGGID_00159 4.3e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KFCOGGID_00160 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
KFCOGGID_00161 0.0 pcrA 3.6.4.12 L DNA helicase
KFCOGGID_00162 8.2e-64 S Domain of unknown function (DUF4418)
KFCOGGID_00163 7.2e-212 V FtsX-like permease family
KFCOGGID_00164 1.3e-127 lolD V ABC transporter
KFCOGGID_00165 1e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFCOGGID_00166 0.0 oatA I Psort location CytoplasmicMembrane, score 9.99
KFCOGGID_00167 6.5e-136 pgm3 G Phosphoglycerate mutase family
KFCOGGID_00168 3.8e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
KFCOGGID_00169 1.1e-36
KFCOGGID_00170 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFCOGGID_00171 3e-75 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFCOGGID_00172 2.7e-187 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFCOGGID_00173 1.4e-46 3.4.23.43 S Type IV leader peptidase family
KFCOGGID_00174 6e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFCOGGID_00175 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFCOGGID_00176 2.2e-78 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KFCOGGID_00177 3.4e-15
KFCOGGID_00178 2.1e-120 K helix_turn_helix, Lux Regulon
KFCOGGID_00179 5.2e-08 3.4.22.70 M Sortase family
KFCOGGID_00180 2.7e-60 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KFCOGGID_00181 6.7e-245 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KFCOGGID_00182 3.6e-290 sufB O FeS assembly protein SufB
KFCOGGID_00183 2.6e-233 sufD O FeS assembly protein SufD
KFCOGGID_00184 1.4e-144 sufC O FeS assembly ATPase SufC
KFCOGGID_00185 1.6e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFCOGGID_00186 1.5e-100 iscU C SUF system FeS assembly protein, NifU family
KFCOGGID_00187 1.2e-108 yitW S Iron-sulfur cluster assembly protein
KFCOGGID_00188 3.2e-177 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KFCOGGID_00189 4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
KFCOGGID_00191 8.1e-83 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KFCOGGID_00192 4.4e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
KFCOGGID_00193 3.4e-197 phoH T PhoH-like protein
KFCOGGID_00194 7.4e-100 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFCOGGID_00195 1.1e-243 corC S CBS domain
KFCOGGID_00196 5.1e-187 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFCOGGID_00197 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KFCOGGID_00198 3.1e-201 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
KFCOGGID_00199 4.4e-44 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
KFCOGGID_00200 6.7e-233 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
KFCOGGID_00201 8.2e-190 S alpha beta
KFCOGGID_00202 8.3e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFCOGGID_00203 4.5e-224 ilvE 2.6.1.42 E Amino-transferase class IV
KFCOGGID_00204 5.8e-45 S phosphoesterase or phosphohydrolase
KFCOGGID_00205 5.1e-98 3.1.4.37 T RNA ligase
KFCOGGID_00206 4.4e-135 S UPF0126 domain
KFCOGGID_00207 9.9e-34 rpsT J Binds directly to 16S ribosomal RNA
KFCOGGID_00208 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KFCOGGID_00209 3.3e-245 hemN H Involved in the biosynthesis of porphyrin-containing compound
KFCOGGID_00210 4e-13 S Membrane
KFCOGGID_00211 6.5e-290 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
KFCOGGID_00212 0.0 tetP J Elongation factor G, domain IV
KFCOGGID_00213 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
KFCOGGID_00214 1e-303 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
KFCOGGID_00215 3.6e-82
KFCOGGID_00216 8.7e-245 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
KFCOGGID_00217 1.6e-182 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
KFCOGGID_00218 3.7e-168 ybeM S Carbon-nitrogen hydrolase
KFCOGGID_00219 8.8e-113 S Sel1-like repeats.
KFCOGGID_00220 2e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
KFCOGGID_00221 1.3e-43 L Integrase core domain protein
KFCOGGID_00222 0.0 hepA L SNF2 family N-terminal domain
KFCOGGID_00223 0.0 V Type II restriction enzyme, methylase
KFCOGGID_00224 0.0 L DEAD-like helicases superfamily
KFCOGGID_00225 0.0 L UvrD-like helicase C-terminal domain
KFCOGGID_00226 1.4e-47 S AAA domain, putative AbiEii toxin, Type IV TA system
KFCOGGID_00227 2.1e-65 L Transposase, Mutator family
KFCOGGID_00228 9.5e-201 L Transposase, Mutator family
KFCOGGID_00229 1.4e-126 L Transposase, Mutator family
KFCOGGID_00230 2.5e-201 L Transposase, Mutator family
KFCOGGID_00231 0.0 S Protein of unknown function DUF262
KFCOGGID_00232 4.5e-19
KFCOGGID_00233 7.7e-103 rarD 3.4.17.13 E Rard protein
KFCOGGID_00234 1.4e-23 rarD S Rard protein
KFCOGGID_00235 3.6e-179 I alpha/beta hydrolase fold
KFCOGGID_00236 9.7e-208 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KFCOGGID_00237 1.3e-99 sixA T Phosphoglycerate mutase family
KFCOGGID_00238 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KFCOGGID_00239 1.1e-158 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
KFCOGGID_00241 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
KFCOGGID_00242 1.4e-181 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KFCOGGID_00243 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
KFCOGGID_00244 6.1e-279 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KFCOGGID_00245 3.4e-180 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
KFCOGGID_00246 2.7e-154 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
KFCOGGID_00247 8.2e-179 pyrD 1.3.1.14 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KFCOGGID_00248 1.1e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFCOGGID_00249 1.7e-193 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
KFCOGGID_00250 1.9e-132
KFCOGGID_00251 2.5e-17 K Psort location Cytoplasmic, score
KFCOGGID_00252 4.5e-15 KLT Protein tyrosine kinase
KFCOGGID_00253 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFCOGGID_00254 1.5e-242 vbsD V MatE
KFCOGGID_00255 1.1e-130 S Enoyl-(Acyl carrier protein) reductase
KFCOGGID_00256 3.9e-133 magIII L endonuclease III
KFCOGGID_00257 1.4e-92 laaE K Transcriptional regulator PadR-like family
KFCOGGID_00258 1.8e-176 S Membrane transport protein
KFCOGGID_00259 2.4e-65 4.1.1.44 S Cupin domain
KFCOGGID_00260 1.3e-223 hipA 2.7.11.1 S HipA N-terminal domain
KFCOGGID_00261 3.7e-41 K Helix-turn-helix
KFCOGGID_00262 3.7e-47 tam 2.1.1.144, 2.1.1.197 FG trans-aconitate 2-methyltransferase activity
KFCOGGID_00263 5.4e-19
KFCOGGID_00264 1.9e-101 K Bacterial regulatory proteins, tetR family
KFCOGGID_00265 9.2e-89 T Domain of unknown function (DUF4234)
KFCOGGID_00266 1.2e-171 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
KFCOGGID_00267 1.2e-122 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KFCOGGID_00268 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFCOGGID_00269 4.4e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
KFCOGGID_00270 2.7e-67 dkgB S Oxidoreductase, aldo keto reductase family protein
KFCOGGID_00272 9.1e-286 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
KFCOGGID_00273 0.0 pafB K WYL domain
KFCOGGID_00274 1e-51
KFCOGGID_00275 0.0 helY L DEAD DEAH box helicase
KFCOGGID_00276 3e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
KFCOGGID_00277 1.6e-142 pgp 3.1.3.18 S HAD-hyrolase-like
KFCOGGID_00280 8.1e-90 K Putative zinc ribbon domain
KFCOGGID_00281 9.7e-67 S GyrI-like small molecule binding domain
KFCOGGID_00282 1.8e-22 L DNA integration
KFCOGGID_00284 1.9e-62
KFCOGGID_00285 8e-120 K helix_turn_helix, mercury resistance
KFCOGGID_00286 3.6e-73 garA T Inner membrane component of T3SS, cytoplasmic domain
KFCOGGID_00287 8.5e-140 S Bacterial protein of unknown function (DUF881)
KFCOGGID_00288 2.6e-31 sbp S Protein of unknown function (DUF1290)
KFCOGGID_00289 4e-173 S Bacterial protein of unknown function (DUF881)
KFCOGGID_00290 1e-116 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFCOGGID_00291 1.8e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
KFCOGGID_00292 6.4e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
KFCOGGID_00293 1.2e-55 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
KFCOGGID_00294 1.3e-179 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFCOGGID_00295 2.4e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KFCOGGID_00296 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KFCOGGID_00297 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
KFCOGGID_00298 7.5e-146 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KFCOGGID_00299 4.1e-103 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
KFCOGGID_00300 2.5e-22
KFCOGGID_00301 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KFCOGGID_00302 3.2e-245
KFCOGGID_00303 4.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFCOGGID_00304 1.9e-225 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KFCOGGID_00305 5.5e-101 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFCOGGID_00306 2.6e-44 yajC U Preprotein translocase subunit
KFCOGGID_00307 1.8e-201 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KFCOGGID_00308 2.5e-104 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KFCOGGID_00310 1.8e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFCOGGID_00311 3e-131 yebC K transcriptional regulatory protein
KFCOGGID_00312 0.0 3.2.1.52 GH20 M Glycosyl hydrolase family 20, catalytic domain
KFCOGGID_00313 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFCOGGID_00314 6.4e-250 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KFCOGGID_00317 2.3e-08
KFCOGGID_00318 2e-211
KFCOGGID_00322 3.1e-155 S PAC2 family
KFCOGGID_00323 6.5e-168 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KFCOGGID_00324 1.2e-159 G Fructosamine kinase
KFCOGGID_00325 3.4e-211 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KFCOGGID_00326 2.6e-204 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KFCOGGID_00327 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
KFCOGGID_00328 1e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFCOGGID_00329 1.1e-142 yoaK S Protein of unknown function (DUF1275)
KFCOGGID_00330 7.5e-253 brnQ U Component of the transport system for branched-chain amino acids
KFCOGGID_00331 1.5e-242 mepA_6 V MatE
KFCOGGID_00332 6.1e-162 S Sucrose-6F-phosphate phosphohydrolase
KFCOGGID_00333 1.3e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
KFCOGGID_00334 8e-33 secG U Preprotein translocase SecG subunit
KFCOGGID_00335 5.3e-147 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KFCOGGID_00336 2e-222 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
KFCOGGID_00337 1.5e-172 whiA K May be required for sporulation
KFCOGGID_00338 3.4e-177 rapZ S Displays ATPase and GTPase activities
KFCOGGID_00339 3e-181 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
KFCOGGID_00340 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KFCOGGID_00341 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KFCOGGID_00342 6.1e-77
KFCOGGID_00343 1.6e-59 V MacB-like periplasmic core domain
KFCOGGID_00344 2.1e-117 K Transcriptional regulatory protein, C terminal
KFCOGGID_00345 2.5e-201 L Transposase, Mutator family
KFCOGGID_00346 7.1e-221 qseC 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KFCOGGID_00347 2.2e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KFCOGGID_00348 8.9e-303 ybiT S ABC transporter
KFCOGGID_00349 7.2e-197 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KFCOGGID_00350 1.1e-307 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KFCOGGID_00351 2.8e-207 mdsC 2.7.1.162, 2.7.1.39 S Phosphotransferase enzyme family
KFCOGGID_00352 2.4e-217 GK ROK family
KFCOGGID_00353 6.9e-178 2.7.1.2 GK ROK family
KFCOGGID_00354 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KFCOGGID_00355 1.7e-168 G ABC transporter permease
KFCOGGID_00356 1.1e-173 G Binding-protein-dependent transport system inner membrane component
KFCOGGID_00357 1.9e-247 G Bacterial extracellular solute-binding protein
KFCOGGID_00358 1.3e-309 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFCOGGID_00359 1.2e-73 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFCOGGID_00360 6.7e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KFCOGGID_00361 2e-213 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KFCOGGID_00362 1.8e-176 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
KFCOGGID_00363 2.4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KFCOGGID_00364 2.4e-133 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KFCOGGID_00365 3.3e-126 3.2.1.8 S alpha beta
KFCOGGID_00366 4.8e-146 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFCOGGID_00367 1.4e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
KFCOGGID_00368 1.7e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KFCOGGID_00369 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
KFCOGGID_00370 5.7e-91
KFCOGGID_00371 2.5e-200 guaB 1.1.1.205 F IMP dehydrogenase family protein
KFCOGGID_00372 3.3e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
KFCOGGID_00373 8.7e-274 G ABC transporter substrate-binding protein
KFCOGGID_00374 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
KFCOGGID_00375 2.6e-133 M Peptidase family M23
KFCOGGID_00377 6.2e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFCOGGID_00378 1e-102 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
KFCOGGID_00379 2.7e-160 yeaZ 2.3.1.234 O Glycoprotease family
KFCOGGID_00380 1.5e-118 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
KFCOGGID_00381 1.4e-181 holA 2.7.7.7 L DNA polymerase III delta subunit
KFCOGGID_00382 0.0 comE S Competence protein
KFCOGGID_00383 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
KFCOGGID_00384 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFCOGGID_00385 4.5e-166 ET Bacterial periplasmic substrate-binding proteins
KFCOGGID_00386 4.8e-171 corA P CorA-like Mg2+ transporter protein
KFCOGGID_00387 3.6e-162 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KFCOGGID_00388 1.4e-297 E Serine carboxypeptidase
KFCOGGID_00389 0.0 S Psort location Cytoplasmic, score 8.87
KFCOGGID_00390 1.8e-110 S Domain of unknown function (DUF4194)
KFCOGGID_00391 9.7e-283 S Psort location Cytoplasmic, score 8.87
KFCOGGID_00392 8.2e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KFCOGGID_00393 7.6e-64 yeaO K Protein of unknown function, DUF488
KFCOGGID_00394 1.2e-114 ydaF_1 J Acetyltransferase (GNAT) domain
KFCOGGID_00395 4e-89 MA20_25245 K FR47-like protein
KFCOGGID_00396 4.6e-55 K Transcriptional regulator
KFCOGGID_00397 5.4e-34 2.7.7.1, 3.6.1.13, 3.6.1.55 F Hydrolase of X-linked nucleoside diphosphate N terminal
KFCOGGID_00398 4.1e-20 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
KFCOGGID_00399 9.3e-39 J Aminoacyl-tRNA editing domain
KFCOGGID_00400 1.3e-184 S Acetyltransferase (GNAT) domain
KFCOGGID_00401 2.2e-76 qseC 2.7.13.3 T Histidine kinase
KFCOGGID_00402 6.5e-133 S SOS response associated peptidase (SRAP)
KFCOGGID_00403 8e-123
KFCOGGID_00404 8.1e-79 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFCOGGID_00405 7.5e-164 rpoC M heme binding
KFCOGGID_00406 2.1e-36 EGP Major facilitator Superfamily
KFCOGGID_00407 6.9e-97 EGP Major facilitator Superfamily
KFCOGGID_00409 1.2e-150 3.6.4.12
KFCOGGID_00410 1.2e-10 CE Amino acid permease
KFCOGGID_00411 8.1e-111 ypjC S Putative ABC-transporter type IV
KFCOGGID_00412 3.3e-109 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
KFCOGGID_00413 2.2e-193 V VanZ like family
KFCOGGID_00414 3.5e-146 KT RESPONSE REGULATOR receiver
KFCOGGID_00415 2.7e-70 pdxH S Pfam:Pyridox_oxidase
KFCOGGID_00416 2.9e-141 yijF S Domain of unknown function (DUF1287)
KFCOGGID_00417 4.7e-131 C Putative TM nitroreductase
KFCOGGID_00418 2.3e-101
KFCOGGID_00420 1.2e-254 nplT 3.2.1.1 GH13 G Alpha amylase, catalytic domain
KFCOGGID_00421 1.3e-78 S Bacterial PH domain
KFCOGGID_00422 4.2e-138 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
KFCOGGID_00423 7.9e-68 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KFCOGGID_00424 1.6e-263 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFCOGGID_00426 9.1e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFCOGGID_00427 4.7e-145 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFCOGGID_00428 3.7e-91
KFCOGGID_00429 4e-237 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFCOGGID_00430 1.1e-283 thrC 4.2.3.1 E Threonine synthase N terminus
KFCOGGID_00431 8.1e-123 S ABC-2 family transporter protein
KFCOGGID_00432 3.7e-126 S ABC-2 family transporter protein
KFCOGGID_00433 4.2e-175 V ATPases associated with a variety of cellular activities
KFCOGGID_00434 3.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
KFCOGGID_00435 3.4e-123 S Haloacid dehalogenase-like hydrolase
KFCOGGID_00436 2.9e-294 recN L May be involved in recombinational repair of damaged DNA
KFCOGGID_00437 7.3e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFCOGGID_00438 3.3e-235 trkB P Cation transport protein
KFCOGGID_00439 6.8e-116 trkA P TrkA-N domain
KFCOGGID_00440 6.1e-104
KFCOGGID_00441 3.6e-137 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
KFCOGGID_00443 1.5e-189 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KFCOGGID_00444 1.6e-155 L Tetratricopeptide repeat
KFCOGGID_00446 3.7e-254 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFCOGGID_00447 3.9e-142 S Putative ABC-transporter type IV
KFCOGGID_00448 7.2e-109 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
KFCOGGID_00449 3.1e-276 argH 4.3.2.1 E argininosuccinate lyase
KFCOGGID_00450 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KFCOGGID_00451 2.5e-201 L Transposase, Mutator family
KFCOGGID_00452 2e-205 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
KFCOGGID_00453 1.1e-284 3.6.4.12 K Putative DNA-binding domain
KFCOGGID_00454 6.2e-67 3.1.21.3 V Type I restriction
KFCOGGID_00455 0.0 hsdM 2.1.1.72 V modification (methylase) protein of type I restriction-modification system K03427
KFCOGGID_00456 6.5e-156 S Domain of unknown function (DUF4357)
KFCOGGID_00457 2.4e-30
KFCOGGID_00458 4e-178 L Phage integrase family
KFCOGGID_00459 1.5e-40 2.1.1.72, 3.1.21.3 V type I restriction modification DNA specificity domain
KFCOGGID_00460 4.1e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KFCOGGID_00461 1.4e-84 argR K Regulates arginine biosynthesis genes
KFCOGGID_00462 5e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFCOGGID_00463 1.6e-246 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
KFCOGGID_00464 1.7e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KFCOGGID_00465 1.9e-214 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFCOGGID_00466 9.4e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFCOGGID_00467 1.3e-87
KFCOGGID_00468 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
KFCOGGID_00469 9.1e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFCOGGID_00470 5.4e-161 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFCOGGID_00471 9.9e-135 ybbL V ATPases associated with a variety of cellular activities
KFCOGGID_00472 2.5e-136 ybbM V Uncharacterised protein family (UPF0014)
KFCOGGID_00473 3.7e-51 IQ oxidoreductase activity
KFCOGGID_00475 2.5e-201 L Transposase, Mutator family
KFCOGGID_00476 5e-81 K AraC-like ligand binding domain
KFCOGGID_00477 1.4e-237 rutG F Permease family
KFCOGGID_00478 3.1e-158 3.1.3.73 G Phosphoglycerate mutase family
KFCOGGID_00479 3.9e-63 S Phospholipase/Carboxylesterase
KFCOGGID_00480 1.2e-186 MA20_14895 S Conserved hypothetical protein 698
KFCOGGID_00481 1.9e-144 rlrG K Bacterial regulatory helix-turn-helix protein, lysR family
KFCOGGID_00482 1.2e-117 3.1.3.27 E haloacid dehalogenase-like hydrolase
KFCOGGID_00483 1.1e-289 2.4.1.166 GT2 M Glycosyltransferase like family 2
KFCOGGID_00485 0.0 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KFCOGGID_00486 1e-124 ypfH S Phospholipase/Carboxylesterase
KFCOGGID_00487 2.7e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
KFCOGGID_00488 3.9e-25
KFCOGGID_00489 1.2e-34 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
KFCOGGID_00490 2.5e-201 L Transposase, Mutator family
KFCOGGID_00491 2.8e-66 S Zincin-like metallopeptidase
KFCOGGID_00492 2.7e-87 S Helix-turn-helix
KFCOGGID_00493 3.9e-197 S Short C-terminal domain
KFCOGGID_00494 2.7e-22
KFCOGGID_00495 1.1e-149
KFCOGGID_00496 4.5e-79 K Psort location Cytoplasmic, score
KFCOGGID_00497 2.9e-256 KLT Protein tyrosine kinase
KFCOGGID_00498 2.1e-66 S Cupin 2, conserved barrel domain protein
KFCOGGID_00499 2.3e-156 ksgA 2.1.1.182 J Methyltransferase domain
KFCOGGID_00500 5.6e-59 yccF S Inner membrane component domain
KFCOGGID_00501 6.6e-120 E Psort location Cytoplasmic, score 8.87
KFCOGGID_00502 1.3e-34 L Psort location Cytoplasmic, score 8.87
KFCOGGID_00503 3.7e-124 L Integrase core domain
KFCOGGID_00504 4.6e-16
KFCOGGID_00506 3.4e-09
KFCOGGID_00507 4.1e-60 S competence protein
KFCOGGID_00508 6.5e-118 dprA LU DNA recombination-mediator protein A
KFCOGGID_00509 6.8e-08 int L Phage integrase, N-terminal SAM-like domain
KFCOGGID_00510 9.7e-30
KFCOGGID_00511 2.2e-27 S Protein of unknown function (DUF3800)
KFCOGGID_00512 2.4e-194 int L Phage integrase, N-terminal SAM-like domain
KFCOGGID_00513 1.4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KFCOGGID_00514 7.6e-230 mtnE 2.6.1.83 E Aminotransferase class I and II
KFCOGGID_00515 2.9e-93 metI P Binding-protein-dependent transport system inner membrane component
KFCOGGID_00516 4.4e-203 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFCOGGID_00517 3.9e-182 1.2.4.1 C Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit
KFCOGGID_00518 1.7e-196 acoA 1.2.4.1 C Dehydrogenase E1 component
KFCOGGID_00519 5.5e-147 P NLPA lipoprotein
KFCOGGID_00520 2.1e-166 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
KFCOGGID_00521 7.2e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFCOGGID_00522 5.5e-264 pip 3.4.11.5 S alpha/beta hydrolase fold
KFCOGGID_00523 0.0 tcsS2 T Histidine kinase
KFCOGGID_00524 2.3e-131 K helix_turn_helix, Lux Regulon
KFCOGGID_00525 0.0 phoN I PAP2 superfamily
KFCOGGID_00526 0.0 MV MacB-like periplasmic core domain
KFCOGGID_00527 4e-162 V ABC transporter, ATP-binding protein
KFCOGGID_00528 2.6e-252 metY 2.5.1.49 E Aminotransferase class-V
KFCOGGID_00529 1e-156 S Putative ABC-transporter type IV
KFCOGGID_00530 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
KFCOGGID_00531 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
KFCOGGID_00532 8.8e-284 dprA 5.99.1.2 LU DNA recombination-mediator protein A
KFCOGGID_00533 1.9e-294 comM O Magnesium chelatase, subunit ChlI C-terminal
KFCOGGID_00534 3e-71 yraN L Belongs to the UPF0102 family
KFCOGGID_00535 6.6e-184 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
KFCOGGID_00536 1.1e-118 safC S O-methyltransferase
KFCOGGID_00537 8.4e-168 fmt2 3.2.2.10 S Belongs to the LOG family
KFCOGGID_00538 9.1e-226 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFCOGGID_00539 2.9e-234 patB 4.4.1.8 E Aminotransferase, class I II
KFCOGGID_00542 7.7e-244 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFCOGGID_00543 9.4e-127 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KFCOGGID_00544 1.1e-112 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KFCOGGID_00545 1.5e-250 clcA_2 P Voltage gated chloride channel
KFCOGGID_00546 2.8e-236 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KFCOGGID_00547 2.3e-248 rnd 3.1.13.5 J 3'-5' exonuclease
KFCOGGID_00548 1.3e-113 S Protein of unknown function (DUF3000)
KFCOGGID_00549 3.9e-175 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KFCOGGID_00550 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
KFCOGGID_00551 4.4e-38
KFCOGGID_00552 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFCOGGID_00553 5.9e-224 S Peptidase dimerisation domain
KFCOGGID_00554 4.9e-91 P ABC-type metal ion transport system permease component
KFCOGGID_00555 7.1e-166 S Sucrose-6F-phosphate phosphohydrolase
KFCOGGID_00556 5.4e-103 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFCOGGID_00557 5e-50 relB L RelB antitoxin
KFCOGGID_00558 1.8e-68 T Toxic component of a toxin-antitoxin (TA) module
KFCOGGID_00559 8e-28
KFCOGGID_00560 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFCOGGID_00561 2.2e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
KFCOGGID_00562 6.5e-37 S Domain of unknown function (DUF4193)
KFCOGGID_00563 1.5e-186 S Protein of unknown function (DUF3071)
KFCOGGID_00564 6.5e-237 S Type I phosphodiesterase / nucleotide pyrophosphatase
KFCOGGID_00565 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KFCOGGID_00566 0.0 lhr L DEAD DEAH box helicase
KFCOGGID_00567 7.3e-24 yozG K Cro/C1-type HTH DNA-binding domain
KFCOGGID_00568 1.6e-49 S Protein of unknown function (DUF2975)
KFCOGGID_00569 4.9e-276 aspA 4.3.1.1 E Fumarase C C-terminus
KFCOGGID_00570 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
KFCOGGID_00571 6.3e-181 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KFCOGGID_00572 1.7e-122
KFCOGGID_00573 5.2e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
KFCOGGID_00574 0.0 pknL 2.7.11.1 KLT PASTA
KFCOGGID_00575 1e-133 plsC2 2.3.1.51 I Phosphate acyltransferases
KFCOGGID_00576 1.6e-108
KFCOGGID_00577 5.4e-192 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFCOGGID_00578 3.5e-189 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KFCOGGID_00579 4.4e-295 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KFCOGGID_00580 6.7e-111 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KFCOGGID_00581 1e-07
KFCOGGID_00582 1.1e-86 recX S Modulates RecA activity
KFCOGGID_00583 8e-216 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFCOGGID_00584 3.7e-40 S Protein of unknown function (DUF3046)
KFCOGGID_00585 2.6e-78 K Helix-turn-helix XRE-family like proteins
KFCOGGID_00586 1.3e-96 cinA 3.5.1.42 S Belongs to the CinA family
KFCOGGID_00587 1.9e-121 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFCOGGID_00588 0.0 ftsK D FtsK SpoIIIE family protein
KFCOGGID_00589 2e-137 fic D Fic/DOC family
KFCOGGID_00590 5.5e-122 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFCOGGID_00591 2.8e-279 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFCOGGID_00592 9.3e-121 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
KFCOGGID_00593 7.5e-172 ydeD EG EamA-like transporter family
KFCOGGID_00594 6.6e-132 ybhL S Belongs to the BI1 family
KFCOGGID_00595 1e-97 S Domain of unknown function (DUF5067)
KFCOGGID_00596 5e-150 T Histidine kinase
KFCOGGID_00597 4.8e-78 T Histidine kinase
KFCOGGID_00598 9.1e-116 K helix_turn_helix, Lux Regulon
KFCOGGID_00599 0.0 S Protein of unknown function DUF262
KFCOGGID_00600 2e-302 gmk 2.4.2.10, 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
KFCOGGID_00601 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
KFCOGGID_00602 1.2e-238 carA 6.3.5.5 F Belongs to the CarA family
KFCOGGID_00603 8e-88 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFCOGGID_00604 3.3e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFCOGGID_00606 1.1e-190 EGP Transmembrane secretion effector
KFCOGGID_00607 0.0 S Esterase-like activity of phytase
KFCOGGID_00608 8.1e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFCOGGID_00609 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFCOGGID_00610 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KFCOGGID_00611 9.3e-62 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFCOGGID_00613 1.3e-198 ltaE 4.1.2.48 E Beta-eliminating lyase
KFCOGGID_00614 4.1e-228 M Glycosyl transferase 4-like domain
KFCOGGID_00616 0.0 M Parallel beta-helix repeats
KFCOGGID_00617 6.1e-167 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFCOGGID_00618 5.1e-51 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFCOGGID_00619 1.5e-138 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KFCOGGID_00620 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
KFCOGGID_00621 2.7e-107
KFCOGGID_00622 1.1e-94 S Protein of unknown function (DUF4230)
KFCOGGID_00623 2e-149 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
KFCOGGID_00624 7.1e-28 K DNA-binding transcription factor activity
KFCOGGID_00625 1.8e-68 MA20_22310 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFCOGGID_00626 2e-32
KFCOGGID_00627 6.1e-304 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
KFCOGGID_00628 3e-275 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KFCOGGID_00629 4.9e-162 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KFCOGGID_00630 5e-240 purD 6.3.4.13 F Belongs to the GARS family
KFCOGGID_00631 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
KFCOGGID_00632 1.2e-247 S Putative esterase
KFCOGGID_00633 0.0 lysX S Uncharacterised conserved protein (DUF2156)
KFCOGGID_00635 1.3e-162 P Zinc-uptake complex component A periplasmic
KFCOGGID_00636 3.9e-139 S cobalamin synthesis protein
KFCOGGID_00637 6.1e-48 rpmB J Ribosomal L28 family
KFCOGGID_00638 7.5e-49 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFCOGGID_00639 2e-42 rpmE2 J Ribosomal protein L31
KFCOGGID_00640 8.2e-15 rpmJ J Ribosomal protein L36
KFCOGGID_00641 5.1e-23 J Ribosomal L32p protein family
KFCOGGID_00642 1.3e-199 ycgR S Predicted permease
KFCOGGID_00643 7.7e-154 S TIGRFAM TIGR03943 family protein
KFCOGGID_00644 6.4e-44
KFCOGGID_00645 4.3e-73 zur P Belongs to the Fur family
KFCOGGID_00646 6.2e-229 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFCOGGID_00647 4.7e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFCOGGID_00648 2.9e-179 adh3 C Zinc-binding dehydrogenase
KFCOGGID_00649 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFCOGGID_00651 2e-43 S Memo-like protein
KFCOGGID_00652 1.4e-226 K Putative ATP-dependent DNA helicase recG C-terminal
KFCOGGID_00653 3.5e-160 K Helix-turn-helix domain, rpiR family
KFCOGGID_00654 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KFCOGGID_00655 2.3e-248 dgt 3.1.5.1 F Phosphohydrolase-associated domain
KFCOGGID_00656 2e-263 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFCOGGID_00657 1.5e-269 yhdG E aromatic amino acid transport protein AroP K03293
KFCOGGID_00658 7.1e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFCOGGID_00659 2.7e-31 J Acetyltransferase (GNAT) domain
KFCOGGID_00660 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KFCOGGID_00661 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
KFCOGGID_00662 2.2e-221 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KFCOGGID_00663 4e-192 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
KFCOGGID_00664 4.4e-109
KFCOGGID_00666 6e-188 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFCOGGID_00667 5.7e-155 sapF E ATPases associated with a variety of cellular activities
KFCOGGID_00668 4e-142 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
KFCOGGID_00669 1.4e-162 EP Binding-protein-dependent transport system inner membrane component
KFCOGGID_00670 5.5e-170 P Binding-protein-dependent transport system inner membrane component
KFCOGGID_00671 4.6e-310 E ABC transporter, substrate-binding protein, family 5
KFCOGGID_00672 3.6e-143 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFCOGGID_00673 7.5e-277 G Bacterial extracellular solute-binding protein
KFCOGGID_00674 1.1e-56 G carbohydrate transport
KFCOGGID_00675 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KFCOGGID_00676 2.6e-126 G ABC transporter permease
KFCOGGID_00677 2.9e-190 K Periplasmic binding protein domain
KFCOGGID_00678 1.4e-17 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
KFCOGGID_00679 0.0 3.2.1.51 GH29 G Alpha-L-fucosidase
KFCOGGID_00681 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFCOGGID_00682 1.5e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
KFCOGGID_00683 7.1e-275 aldH 1.2.1.3, 1.2.1.5 C Aldehyde dehydrogenase family
KFCOGGID_00684 4.9e-128 XK27_08050 O prohibitin homologues
KFCOGGID_00685 4.5e-244 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
KFCOGGID_00686 2e-233 metC 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KFCOGGID_00687 2.1e-260 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
KFCOGGID_00688 4.7e-227 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KFCOGGID_00689 0.0 macB_2 V ATPases associated with a variety of cellular activities
KFCOGGID_00690 0.0 ctpE P E1-E2 ATPase
KFCOGGID_00691 2.3e-33 K acetyltransferase
KFCOGGID_00692 3.2e-53 racA K MerR, DNA binding
KFCOGGID_00693 1.1e-194 yghZ C Aldo/keto reductase family
KFCOGGID_00694 5.1e-101 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
KFCOGGID_00695 1.1e-250 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
KFCOGGID_00696 1.1e-149 map 3.4.11.18 E Methionine aminopeptidase
KFCOGGID_00697 2.6e-121 S Short repeat of unknown function (DUF308)
KFCOGGID_00698 0.0 pepO 3.4.24.71 O Peptidase family M13
KFCOGGID_00699 1.6e-120 L Single-strand binding protein family
KFCOGGID_00700 1.2e-169
KFCOGGID_00701 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KFCOGGID_00703 3.1e-267 recD2 3.6.4.12 L PIF1-like helicase
KFCOGGID_00704 4e-161 supH S Sucrose-6F-phosphate phosphohydrolase
KFCOGGID_00705 2.8e-122 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFCOGGID_00706 2.7e-26 KT Transcriptional regulatory protein, C terminal
KFCOGGID_00707 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
KFCOGGID_00708 3.5e-288 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KFCOGGID_00709 6.2e-192 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
KFCOGGID_00710 5.2e-116 ywlC 2.7.7.87 J Belongs to the SUA5 family
KFCOGGID_00711 2.4e-55 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
KFCOGGID_00712 3e-184 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KFCOGGID_00713 7.7e-189 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFCOGGID_00714 3.9e-36 rpmE J Binds the 23S rRNA
KFCOGGID_00716 1.5e-194 K helix_turn_helix, arabinose operon control protein
KFCOGGID_00717 1.7e-162 glcU G Sugar transport protein
KFCOGGID_00718 2.6e-178 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
KFCOGGID_00719 3.5e-257 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
KFCOGGID_00720 6.2e-107
KFCOGGID_00721 9.5e-201 L Transposase, Mutator family
KFCOGGID_00722 4.8e-129 S Metallo-beta-lactamase domain protein
KFCOGGID_00723 9.5e-201 L Transposase, Mutator family
KFCOGGID_00724 1.1e-169 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
KFCOGGID_00725 4.7e-141 3.5.2.6 V Beta-lactamase enzyme family
KFCOGGID_00726 0.0 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
KFCOGGID_00727 4.2e-164 EG EamA-like transporter family
KFCOGGID_00729 4.5e-125 V FtsX-like permease family
KFCOGGID_00730 2e-147 S Sulfite exporter TauE/SafE
KFCOGGID_00731 4.4e-216 MA20_36090 S Psort location Cytoplasmic, score 8.87
KFCOGGID_00732 3.4e-252 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
KFCOGGID_00733 4.6e-35 1.1.1.122, 1.1.1.65 C Aldo/keto reductase family
KFCOGGID_00734 1.2e-72 EGP Major facilitator superfamily
KFCOGGID_00735 6.3e-179 glkA 2.7.1.2 G ROK family
KFCOGGID_00736 1.3e-301 S ATPases associated with a variety of cellular activities
KFCOGGID_00737 9.3e-56 EGP Major facilitator Superfamily
KFCOGGID_00738 2.2e-159 I alpha/beta hydrolase fold
KFCOGGID_00739 6.5e-116 S Pyridoxamine 5'-phosphate oxidase
KFCOGGID_00741 1.7e-48 S DUF218 domain
KFCOGGID_00742 5.8e-108 S Protein of unknown function (DUF969)
KFCOGGID_00743 1.4e-157 S Protein of unknown function (DUF979)
KFCOGGID_00744 9.7e-115 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KFCOGGID_00746 5.7e-126
KFCOGGID_00747 1.1e-161 M domain, Protein
KFCOGGID_00748 4e-19 M domain, Protein
KFCOGGID_00749 2.4e-306 yjjK S ATP-binding cassette protein, ChvD family
KFCOGGID_00750 0.0 3.2.1.52, 3.2.1.83 GH16,GH20 G hydrolase family 20, catalytic
KFCOGGID_00751 2.1e-171 tesB I Thioesterase-like superfamily
KFCOGGID_00752 1.9e-76 S Protein of unknown function (DUF3180)
KFCOGGID_00753 4.3e-291 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFCOGGID_00754 3.4e-163 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFCOGGID_00755 4.5e-100 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
KFCOGGID_00756 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFCOGGID_00757 9.4e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KFCOGGID_00758 2.3e-212 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KFCOGGID_00759 5.3e-262 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
KFCOGGID_00760 2.3e-309
KFCOGGID_00761 1.7e-168 natA V ATPases associated with a variety of cellular activities
KFCOGGID_00762 1.3e-232 epsG M Glycosyl transferase family 21
KFCOGGID_00763 3.9e-274 S AI-2E family transporter
KFCOGGID_00764 1.9e-177 3.4.14.13 M Glycosyltransferase like family 2
KFCOGGID_00765 8.1e-205 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
KFCOGGID_00768 4.8e-67 S Domain of unknown function (DUF4190)
KFCOGGID_00769 9.9e-199 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KFCOGGID_00770 3.5e-154 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KFCOGGID_00772 1.7e-268 lacS G Psort location CytoplasmicMembrane, score 10.00
KFCOGGID_00773 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KFCOGGID_00774 2.5e-86 nagA 3.5.1.25 G Amidohydrolase family
KFCOGGID_00775 7.5e-183 lacR K Transcriptional regulator, LacI family
KFCOGGID_00776 5.2e-229 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KFCOGGID_00777 3.9e-119 K Transcriptional regulatory protein, C terminal
KFCOGGID_00778 2.2e-95
KFCOGGID_00779 1.5e-178 V N-Acetylmuramoyl-L-alanine amidase
KFCOGGID_00780 1.6e-108 ytrE V ABC transporter
KFCOGGID_00781 1.5e-171
KFCOGGID_00783 4.7e-220 vex3 V ABC transporter permease
KFCOGGID_00784 1.6e-211 vex1 V Efflux ABC transporter, permease protein
KFCOGGID_00785 1.3e-111 vex2 V ABC transporter, ATP-binding protein
KFCOGGID_00786 2.2e-45 azlD E Branched-chain amino acid transport protein (AzlD)
KFCOGGID_00787 2.2e-196 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
KFCOGGID_00788 2.1e-96 ptpA 3.1.3.48 T low molecular weight
KFCOGGID_00789 4.6e-128 folA 1.5.1.3 H dihydrofolate reductase
KFCOGGID_00790 1.9e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFCOGGID_00791 3.8e-72 attW O OsmC-like protein
KFCOGGID_00792 1.6e-191 T Universal stress protein family
KFCOGGID_00793 2.4e-107 M NlpC/P60 family
KFCOGGID_00794 3.1e-176 usp 3.5.1.28 CBM50 S CHAP domain
KFCOGGID_00795 8.5e-215 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFCOGGID_00796 2.6e-39
KFCOGGID_00797 2.8e-219 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
KFCOGGID_00798 1.3e-117 phoU P Plays a role in the regulation of phosphate uptake
KFCOGGID_00799 1.8e-09 EGP Major facilitator Superfamily
KFCOGGID_00800 4.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KFCOGGID_00801 4e-173 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KFCOGGID_00802 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KFCOGGID_00804 2.8e-216 araJ EGP Major facilitator Superfamily
KFCOGGID_00805 0.0 S Domain of unknown function (DUF4037)
KFCOGGID_00806 1.6e-111 S Protein of unknown function (DUF4125)
KFCOGGID_00807 1.2e-124
KFCOGGID_00808 1.1e-285 pspC KT PspC domain
KFCOGGID_00809 1e-268 tcsS3 KT PspC domain
KFCOGGID_00810 8.5e-126 degU K helix_turn_helix, Lux Regulon
KFCOGGID_00811 2.9e-22 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFCOGGID_00812 2e-241 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFCOGGID_00814 2.3e-142 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
KFCOGGID_00815 9.4e-186 opcA G Glucose-6-phosphate dehydrogenase subunit
KFCOGGID_00816 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFCOGGID_00817 2.2e-93
KFCOGGID_00819 0.0 nagLU 3.1.4.53, 3.2.1.21, 3.2.1.50 GH3 G Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain
KFCOGGID_00821 3.3e-229 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFCOGGID_00822 0.0 nucH 3.1.3.5 F 5'-nucleotidase, C-terminal domain
KFCOGGID_00823 5.1e-212 I Diacylglycerol kinase catalytic domain
KFCOGGID_00824 1.9e-127 arbG K CAT RNA binding domain
KFCOGGID_00825 0.0 crr G pts system, glucose-specific IIABC component
KFCOGGID_00826 5.7e-28 M Spy0128-like isopeptide containing domain
KFCOGGID_00827 6.1e-43 M Spy0128-like isopeptide containing domain
KFCOGGID_00828 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
KFCOGGID_00829 1.9e-259 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFCOGGID_00830 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
KFCOGGID_00831 3.5e-202 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFCOGGID_00832 5.4e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFCOGGID_00834 1.2e-106
KFCOGGID_00835 1.8e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFCOGGID_00836 6.9e-234 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
KFCOGGID_00837 1.6e-238 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFCOGGID_00838 1.4e-83 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFCOGGID_00839 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFCOGGID_00840 2.8e-188 nusA K Participates in both transcription termination and antitermination
KFCOGGID_00841 1e-160
KFCOGGID_00842 5.7e-43 L Transposase and inactivated derivatives
KFCOGGID_00843 8.3e-26
KFCOGGID_00845 5e-153 E Transglutaminase/protease-like homologues
KFCOGGID_00846 0.0 gcs2 S A circularly permuted ATPgrasp
KFCOGGID_00847 6.4e-173 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KFCOGGID_00848 0.0 3.2.1.52 GH20 G hydrolase family 20, catalytic
KFCOGGID_00849 8.1e-64 rplQ J Ribosomal protein L17
KFCOGGID_00850 8.9e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFCOGGID_00851 1.1e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFCOGGID_00852 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFCOGGID_00853 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KFCOGGID_00854 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFCOGGID_00855 3.8e-99 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KFCOGGID_00856 4.7e-249 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KFCOGGID_00857 2.7e-63 rplO J binds to the 23S rRNA
KFCOGGID_00858 1e-24 rpmD J Ribosomal protein L30p/L7e
KFCOGGID_00859 1.5e-100 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFCOGGID_00860 1.1e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFCOGGID_00861 2.1e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFCOGGID_00862 4.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFCOGGID_00863 9.2e-18 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFCOGGID_00864 2.2e-102 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFCOGGID_00865 3.5e-52 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFCOGGID_00866 6.6e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFCOGGID_00867 3.5e-42 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFCOGGID_00868 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
KFCOGGID_00869 5.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFCOGGID_00870 7.5e-96 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFCOGGID_00871 4.3e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFCOGGID_00872 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFCOGGID_00873 4.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFCOGGID_00874 9.8e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KFCOGGID_00875 3.9e-119 rplD J Forms part of the polypeptide exit tunnel
KFCOGGID_00876 4.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFCOGGID_00877 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
KFCOGGID_00878 7.2e-114 ywiC S YwiC-like protein
KFCOGGID_00879 2.4e-27 ywiC S YwiC-like protein
KFCOGGID_00880 1.9e-166 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KFCOGGID_00881 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
KFCOGGID_00882 4.1e-231 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
KFCOGGID_00883 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KFCOGGID_00884 8.8e-68 rpsI J Belongs to the universal ribosomal protein uS9 family
KFCOGGID_00885 3.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFCOGGID_00886 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
KFCOGGID_00887 3.2e-109
KFCOGGID_00888 1.8e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
KFCOGGID_00889 1.1e-256 M Bacterial capsule synthesis protein PGA_cap
KFCOGGID_00891 1.5e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFCOGGID_00892 6.3e-221 dapC E Aminotransferase class I and II
KFCOGGID_00893 9e-61 fdxA C 4Fe-4S binding domain
KFCOGGID_00894 1.5e-214 murB 1.3.1.98 M Cell wall formation
KFCOGGID_00895 1.9e-25 rpmG J Ribosomal protein L33
KFCOGGID_00899 7.1e-52 moxR S ATPase family associated with various cellular activities (AAA)
KFCOGGID_00900 4e-128 bla1 3.5.2.6 V Beta-lactamase enzyme family
KFCOGGID_00901 1.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFCOGGID_00902 1.1e-139
KFCOGGID_00903 2e-93 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
KFCOGGID_00904 5.4e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
KFCOGGID_00905 3.2e-38 fmdB S Putative regulatory protein
KFCOGGID_00906 3.6e-109 flgA NO SAF
KFCOGGID_00907 9.6e-42
KFCOGGID_00908 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
KFCOGGID_00909 5e-240 T Forkhead associated domain
KFCOGGID_00911 1.3e-37 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KFCOGGID_00912 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFCOGGID_00913 4.5e-183 xynB2 1.1.1.169 E lipolytic protein G-D-S-L family
KFCOGGID_00914 0.0 guxA1 3.2.1.18, 3.2.1.91 GH33,GH6 G BNR repeat-like domain
KFCOGGID_00916 8.8e-222 pbuO S Permease family
KFCOGGID_00917 1.4e-12 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_00918 1.9e-159 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_00919 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KFCOGGID_00920 1.4e-179 pstA P Phosphate transport system permease
KFCOGGID_00921 3.8e-171 pstC P probably responsible for the translocation of the substrate across the membrane
KFCOGGID_00922 2.3e-172 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
KFCOGGID_00923 1.3e-128 KT Transcriptional regulatory protein, C terminal
KFCOGGID_00924 2.2e-241 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KFCOGGID_00925 7.3e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KFCOGGID_00926 1.7e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFCOGGID_00927 1e-105 K helix_turn_helix, Arsenical Resistance Operon Repressor
KFCOGGID_00928 3e-246 EGP Major facilitator Superfamily
KFCOGGID_00929 1.5e-219 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFCOGGID_00930 2.7e-167 L Excalibur calcium-binding domain
KFCOGGID_00931 3.9e-267 pepC 3.4.22.40 E Peptidase C1-like family
KFCOGGID_00932 3.4e-46 D nuclear chromosome segregation
KFCOGGID_00933 8e-128 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KFCOGGID_00934 6.5e-145 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KFCOGGID_00935 7.9e-188 yfiH Q Multi-copper polyphenol oxidoreductase laccase
KFCOGGID_00936 0.0 yegQ O Peptidase family U32 C-terminal domain
KFCOGGID_00937 8.7e-94 L Transposase and inactivated derivatives IS30 family
KFCOGGID_00938 3.8e-96 L Transposase and inactivated derivatives IS30 family
KFCOGGID_00939 4.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
KFCOGGID_00940 2.2e-41 nrdH O Glutaredoxin
KFCOGGID_00941 7.3e-98 nrdI F Probably involved in ribonucleotide reductase function
KFCOGGID_00942 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFCOGGID_00943 1.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFCOGGID_00944 1.3e-73 megL 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
KFCOGGID_00945 0.0 S Predicted membrane protein (DUF2207)
KFCOGGID_00946 1e-91 lemA S LemA family
KFCOGGID_00947 7.2e-116 xylR K purine nucleotide biosynthetic process
KFCOGGID_00948 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KFCOGGID_00949 3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFCOGGID_00950 3.4e-118
KFCOGGID_00951 0.0 nagH 3.2.1.35, 3.2.1.52 GH20 G beta-N-acetylglucosaminidase
KFCOGGID_00953 8.4e-162 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KFCOGGID_00954 5e-99 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KFCOGGID_00955 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
KFCOGGID_00956 3.6e-307 pccB I Carboxyl transferase domain
KFCOGGID_00957 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
KFCOGGID_00958 1.2e-92 bioY S BioY family
KFCOGGID_00959 9.9e-152 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
KFCOGGID_00960 0.0
KFCOGGID_00961 1e-145 QT PucR C-terminal helix-turn-helix domain
KFCOGGID_00962 6.3e-81 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
KFCOGGID_00963 8.7e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KFCOGGID_00964 1.5e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFCOGGID_00965 2.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFCOGGID_00966 0.0 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFCOGGID_00967 2.4e-150 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFCOGGID_00968 4.6e-62 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFCOGGID_00969 1.2e-30 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFCOGGID_00971 6e-146 atpB C it plays a direct role in the translocation of protons across the membrane
KFCOGGID_00972 1.6e-207 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFCOGGID_00974 1.7e-34
KFCOGGID_00975 0.0 K RNA polymerase II activating transcription factor binding
KFCOGGID_00976 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
KFCOGGID_00977 5.2e-92 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFCOGGID_00978 1.3e-102 mntP P Probably functions as a manganese efflux pump
KFCOGGID_00979 1.4e-125
KFCOGGID_00980 1.5e-132 KT Transcriptional regulatory protein, C terminal
KFCOGGID_00981 3e-127 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFCOGGID_00982 3.3e-294 E Bacterial extracellular solute-binding proteins, family 5 Middle
KFCOGGID_00983 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KFCOGGID_00984 0.0 S domain protein
KFCOGGID_00985 4.7e-73 tyrA 5.4.99.5 E Chorismate mutase type II
KFCOGGID_00986 2.4e-90 lrp_3 K helix_turn_helix ASNC type
KFCOGGID_00987 3e-234 E Aminotransferase class I and II
KFCOGGID_00988 5.6e-305 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFCOGGID_00989 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
KFCOGGID_00990 3.3e-52 S Protein of unknown function (DUF2469)
KFCOGGID_00991 2.5e-197 2.3.1.57 J Acetyltransferase (GNAT) domain
KFCOGGID_00992 1.4e-286 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFCOGGID_00993 1.1e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KFCOGGID_00994 6.2e-48 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFCOGGID_00995 6.2e-61 V ABC transporter
KFCOGGID_00996 3.3e-59 V ABC transporter
KFCOGGID_00997 6.9e-156 spoU 2.1.1.185 J RNA methyltransferase TrmH family
KFCOGGID_00998 1.3e-128 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFCOGGID_00999 1.3e-214 rmuC S RmuC family
KFCOGGID_01000 9.6e-43 csoR S Metal-sensitive transcriptional repressor
KFCOGGID_01001 8e-23 pacS 3.6.3.54 P E1-E2 ATPase
KFCOGGID_01002 0.0 pacS 3.6.3.54 P E1-E2 ATPase
KFCOGGID_01003 0.0 ubiB S ABC1 family
KFCOGGID_01004 3.5e-19 S granule-associated protein
KFCOGGID_01005 7.5e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
KFCOGGID_01006 1.3e-274 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
KFCOGGID_01007 2.2e-257 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KFCOGGID_01008 7e-251 dinF V MatE
KFCOGGID_01009 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
KFCOGGID_01010 1e-54 glnB K Nitrogen regulatory protein P-II
KFCOGGID_01011 3.4e-220 amt U Ammonium Transporter Family
KFCOGGID_01012 5.3e-202 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KFCOGGID_01014 1.2e-116 icaR K Bacterial regulatory proteins, tetR family
KFCOGGID_01015 1.9e-197 XK27_01805 M Glycosyltransferase like family 2
KFCOGGID_01016 0.0 S Glycosyl hydrolases related to GH101 family, GH129
KFCOGGID_01017 1.6e-304 pepD E Peptidase family C69
KFCOGGID_01019 4.4e-20 XK26_04485 P Cobalt transport protein
KFCOGGID_01020 2.7e-70 XK26_04485 P Cobalt transport protein
KFCOGGID_01021 1.6e-84
KFCOGGID_01022 0.0 V ABC transporter transmembrane region
KFCOGGID_01023 2.4e-301 V ABC transporter, ATP-binding protein
KFCOGGID_01024 1e-81 K Winged helix DNA-binding domain
KFCOGGID_01025 1.3e-14
KFCOGGID_01026 4.7e-115 M LPXTG cell wall anchor motif
KFCOGGID_01027 4.9e-155 M LPXTG cell wall anchor motif
KFCOGGID_01028 6.7e-221 M chlorophyll binding
KFCOGGID_01029 3e-176 3.4.22.70 M Sortase family
KFCOGGID_01031 2.1e-38 S Sucrose-6F-phosphate phosphohydrolase
KFCOGGID_01032 2.7e-241 S Putative ABC-transporter type IV
KFCOGGID_01033 7e-81
KFCOGGID_01034 1.5e-32 Q phosphatase activity
KFCOGGID_01035 1.4e-294 bglA 3.2.1.86 GT1 G Glycosyl hydrolase family 1
KFCOGGID_01036 2e-39 celC 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
KFCOGGID_01037 4.3e-49 celA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
KFCOGGID_01038 2.1e-249 gmuC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KFCOGGID_01039 9.3e-68 S haloacid dehalogenase-like hydrolase
KFCOGGID_01040 3.6e-131 yydK K UTRA
KFCOGGID_01041 1.3e-70 S FMN_bind
KFCOGGID_01042 3.7e-148 macB V ABC transporter, ATP-binding protein
KFCOGGID_01043 7.8e-196 Z012_06715 V FtsX-like permease family
KFCOGGID_01044 1.1e-221 macB_2 V ABC transporter permease
KFCOGGID_01045 3.2e-234 S Predicted membrane protein (DUF2318)
KFCOGGID_01046 6.4e-109 tpd P Fe2+ transport protein
KFCOGGID_01047 0.0 efeU_1 P Iron permease FTR1 family
KFCOGGID_01048 3.2e-30 L Transposase and inactivated derivatives IS30 family
KFCOGGID_01049 3.4e-35 L Psort location Cytoplasmic, score 8.87
KFCOGGID_01050 1.3e-125 L Integrase core domain
KFCOGGID_01051 1.3e-40 2.3.1.39 IQ [acyl-carrier-protein] S-malonyltransferase activity
KFCOGGID_01052 1.2e-264 EGP Major Facilitator Superfamily
KFCOGGID_01053 1.2e-132
KFCOGGID_01054 2.4e-303 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
KFCOGGID_01055 3e-150 L HNH endonuclease
KFCOGGID_01056 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KFCOGGID_01057 0.0 yvnB 3.1.4.53 S Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KFCOGGID_01058 1.8e-88 L Transposase
KFCOGGID_01059 2.1e-41 XAC3035 O Glutaredoxin
KFCOGGID_01060 2.5e-154 S Virulence factor BrkB
KFCOGGID_01061 1.1e-98 bcp 1.11.1.15 O Redoxin
KFCOGGID_01062 9.9e-39 E ABC transporter
KFCOGGID_01063 3e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFCOGGID_01064 2.5e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFCOGGID_01065 0.0 V FtsX-like permease family
KFCOGGID_01066 4.9e-128 V ABC transporter
KFCOGGID_01067 7e-101 K Transcriptional regulator C-terminal region
KFCOGGID_01068 1.5e-275 aroP E aromatic amino acid transport protein AroP K03293
KFCOGGID_01069 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
KFCOGGID_01071 5.3e-181 gmk 1.1.1.23, 2.7.4.8 S Protein of unknown function (DUF559)
KFCOGGID_01072 3.1e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFCOGGID_01073 2.8e-204 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFCOGGID_01074 1e-251 yhjE EGP Sugar (and other) transporter
KFCOGGID_01075 6.5e-296 scrT G Transporter major facilitator family protein
KFCOGGID_01076 2.5e-74 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
KFCOGGID_01077 5.6e-197 K helix_turn _helix lactose operon repressor
KFCOGGID_01078 1.1e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFCOGGID_01079 4.8e-163 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFCOGGID_01080 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFCOGGID_01081 9.9e-11 V TIGR02646 family
KFCOGGID_01082 3.9e-68 S AAA ATPase domain
KFCOGGID_01083 1.2e-199 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
KFCOGGID_01084 2.1e-249 3.5.1.104 G Polysaccharide deacetylase
KFCOGGID_01085 1.5e-38
KFCOGGID_01086 8e-73 ltrBE1 U Relaxase/Mobilisation nuclease domain
KFCOGGID_01087 9.8e-86 ltrBE1 U Relaxase/Mobilisation nuclease domain
KFCOGGID_01088 3.1e-33 S Bacterial mobilisation protein (MobC)
KFCOGGID_01089 2.4e-84 S GyrI-like small molecule binding domain
KFCOGGID_01090 5.7e-41 S Polyketide cyclase / dehydrase and lipid transport
KFCOGGID_01091 6.8e-69 K FR47-like protein
KFCOGGID_01092 1.6e-80 S Nucleotidyltransferase domain
KFCOGGID_01093 1.1e-197
KFCOGGID_01094 1.7e-84 S Protein of unknown function DUF262
KFCOGGID_01095 8.5e-63 S Protein of unknown function DUF262
KFCOGGID_01097 8.1e-171 htpX O Belongs to the peptidase M48B family
KFCOGGID_01098 5e-273 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
KFCOGGID_01099 0.0 cadA P E1-E2 ATPase
KFCOGGID_01100 1.3e-244 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
KFCOGGID_01101 4.9e-259 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KFCOGGID_01103 3.9e-15 2.7.7.7 L Transposase, Mutator family
KFCOGGID_01104 2.6e-57 M Glycosyl hydrolases family 25
KFCOGGID_01105 1.1e-36 CP_0155 3.5.1.28 M LysM domain
KFCOGGID_01106 5.2e-33
KFCOGGID_01107 7e-116 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KFCOGGID_01108 3.2e-79 L HindVP restriction endonuclease
KFCOGGID_01110 4.2e-08
KFCOGGID_01111 6.4e-16 L Phage integrase family
KFCOGGID_01112 5.6e-42 tnp7109-21 L Integrase core domain
KFCOGGID_01113 1.5e-53 tnp7109-21 L Integrase core domain
KFCOGGID_01114 3.9e-50 L transposase activity
KFCOGGID_01115 6.3e-87 yjcF Q Acetyltransferase (GNAT) domain
KFCOGGID_01116 4.2e-155 I Serine aminopeptidase, S33
KFCOGGID_01117 2.7e-52 ybjQ S Putative heavy-metal-binding
KFCOGGID_01118 3.3e-41 D DivIVA domain protein
KFCOGGID_01119 1.3e-90 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
KFCOGGID_01120 0.0 KL Domain of unknown function (DUF3427)
KFCOGGID_01122 5.4e-197 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFCOGGID_01124 2e-103
KFCOGGID_01125 6.2e-166 yicL EG EamA-like transporter family
KFCOGGID_01126 3.9e-206 pldB 3.1.1.5 I Serine aminopeptidase, S33
KFCOGGID_01127 0.0 pip S YhgE Pip domain protein
KFCOGGID_01128 0.0 pip S YhgE Pip domain protein
KFCOGGID_01129 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
KFCOGGID_01130 1e-130 fhaA T Protein of unknown function (DUF2662)
KFCOGGID_01131 1.5e-84 fhaB T Inner membrane component of T3SS, cytoplasmic domain
KFCOGGID_01132 9.2e-258 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
KFCOGGID_01133 2.8e-266 rodA D Belongs to the SEDS family
KFCOGGID_01134 3.4e-264 pbpA M penicillin-binding protein
KFCOGGID_01135 2e-183 T Protein tyrosine kinase
KFCOGGID_01136 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
KFCOGGID_01137 3.4e-120 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
KFCOGGID_01138 2.6e-233 srtA 3.4.22.70 M Sortase family
KFCOGGID_01139 1e-142 S Bacterial protein of unknown function (DUF881)
KFCOGGID_01140 2.6e-71 crgA D Involved in cell division
KFCOGGID_01141 4.7e-257 L ribosomal rna small subunit methyltransferase
KFCOGGID_01142 7.2e-88 L HTH-like domain
KFCOGGID_01143 2.7e-143 gluP 3.4.21.105 S Rhomboid family
KFCOGGID_01144 3.4e-35
KFCOGGID_01145 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KFCOGGID_01146 2e-73 I Sterol carrier protein
KFCOGGID_01147 4.7e-84 V ATPases associated with a variety of cellular activities
KFCOGGID_01148 8.1e-32 L IstB-like ATP binding protein
KFCOGGID_01149 1.1e-42 tnp7109-21 L Integrase core domain
KFCOGGID_01150 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
KFCOGGID_01151 4.5e-12
KFCOGGID_01152 7.5e-17 yccF S Inner membrane component domain
KFCOGGID_01153 1.1e-256 S Domain of unknown function (DUF4143)
KFCOGGID_01154 1.8e-195 L Transposase and inactivated derivatives IS30 family
KFCOGGID_01155 2.2e-193 M Glycosyltransferase like family 2
KFCOGGID_01156 0.0 rgpF M Rhamnan synthesis protein F
KFCOGGID_01157 2.5e-294 S Tetratricopeptide repeat
KFCOGGID_01158 3.7e-208 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
KFCOGGID_01159 3.8e-140 rgpC U Transport permease protein
KFCOGGID_01160 1.2e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KFCOGGID_01161 2.5e-155 L Transposase, Mutator family
KFCOGGID_01162 7.3e-101 L PFAM Integrase catalytic
KFCOGGID_01163 2.2e-105 L transposase activity
KFCOGGID_01164 1.7e-16 L Transposase
KFCOGGID_01165 4.4e-45 L Transposase DDE domain
KFCOGGID_01166 1.6e-290 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KFCOGGID_01167 9.5e-201 L Transposase, Mutator family
KFCOGGID_01168 3.5e-260 3.6.4.12 K Putative DNA-binding domain
KFCOGGID_01169 1.5e-199 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KFCOGGID_01170 0.0
KFCOGGID_01171 2.6e-161 rfbJ M Glycosyl transferase family 2
KFCOGGID_01172 2.5e-201 L Transposase, Mutator family
KFCOGGID_01173 0.0 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
KFCOGGID_01174 7.9e-29 I transferase activity, transferring acyl groups other than amino-acyl groups
KFCOGGID_01175 2.3e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KFCOGGID_01176 2.6e-76 T protein histidine kinase activity
KFCOGGID_01177 2.3e-47 S Protein of unknown function (DUF3073)
KFCOGGID_01178 6.5e-204 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFCOGGID_01179 4.3e-194 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_01180 9.4e-179 S Amidohydrolase family
KFCOGGID_01181 0.0 yjjP S Threonine/Serine exporter, ThrE
KFCOGGID_01182 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KFCOGGID_01183 4.3e-239 yhjX EGP Major facilitator Superfamily
KFCOGGID_01184 0.0 trxB1 1.8.1.9 C Thioredoxin domain
KFCOGGID_01185 2.9e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
KFCOGGID_01186 7.6e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
KFCOGGID_01187 1.8e-52 K helix_turn _helix lactose operon repressor
KFCOGGID_01188 1.2e-241 ytfL P Transporter associated domain
KFCOGGID_01189 1.1e-190 yddG EG EamA-like transporter family
KFCOGGID_01190 1.9e-83 dps P Belongs to the Dps family
KFCOGGID_01191 1.6e-134 S Protein of unknown function DUF45
KFCOGGID_01192 3.5e-261 ulaA 2.7.1.194 S PTS system sugar-specific permease component
KFCOGGID_01193 3.3e-40 ulaC 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
KFCOGGID_01194 8.6e-78 ulaC 2.7.1.194, 2.7.1.197, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
KFCOGGID_01195 1.1e-187 K helix_turn _helix lactose operon repressor
KFCOGGID_01196 0.0 G Glycosyl hydrolase family 20, domain 2
KFCOGGID_01199 0.0 3.2.1.55 GH51 G arabinose metabolic process
KFCOGGID_01200 2.5e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KFCOGGID_01201 4.7e-123 gntR K FCD
KFCOGGID_01202 2.3e-259 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
KFCOGGID_01204 6.7e-09 K helix_turn _helix lactose operon repressor
KFCOGGID_01205 6.1e-229 I Serine aminopeptidase, S33
KFCOGGID_01206 1.8e-186 K Periplasmic binding protein domain
KFCOGGID_01207 1.5e-185 G Glycosyl hydrolases family 43
KFCOGGID_01209 5.7e-21 abfA1 3.2.1.55 GH51 G arabinose metabolic process
KFCOGGID_01210 6.7e-72 S Transmembrane domain of unknown function (DUF3566)
KFCOGGID_01211 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFCOGGID_01212 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFCOGGID_01213 9.9e-87 S Protein of unknown function (DUF721)
KFCOGGID_01214 2e-239 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFCOGGID_01215 7.9e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KFCOGGID_01216 4.1e-300 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFCOGGID_01217 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
KFCOGGID_01218 1e-171 yidC U Membrane protein insertase, YidC Oxa1 family
KFCOGGID_01219 5e-93 jag S Putative single-stranded nucleic acids-binding domain
KFCOGGID_01220 3.5e-126 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
KFCOGGID_01221 8.5e-179 parA D CobQ CobB MinD ParA nucleotide binding domain protein
KFCOGGID_01222 1.2e-242 parB K Belongs to the ParB family
KFCOGGID_01223 2.6e-203 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KFCOGGID_01224 0.0 murJ KLT MviN-like protein
KFCOGGID_01225 0.0 M Conserved repeat domain
KFCOGGID_01226 7.5e-123 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
KFCOGGID_01227 2.8e-279 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
KFCOGGID_01228 6.7e-113 S LytR cell envelope-related transcriptional attenuator
KFCOGGID_01229 7.9e-167 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFCOGGID_01230 4.8e-171 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KFCOGGID_01231 5.9e-211 S G5
KFCOGGID_01233 7.1e-150 O Thioredoxin
KFCOGGID_01234 0.0 KLT Protein tyrosine kinase
KFCOGGID_01235 1.2e-174 K Psort location Cytoplasmic, score
KFCOGGID_01236 3.3e-211 ugpC E Belongs to the ABC transporter superfamily
KFCOGGID_01237 4.3e-103 L Helix-turn-helix domain
KFCOGGID_01238 0.0 S LPXTG-motif cell wall anchor domain protein
KFCOGGID_01239 6.1e-243 M LPXTG-motif cell wall anchor domain protein
KFCOGGID_01240 4.1e-181 3.4.22.70 M Sortase family
KFCOGGID_01241 1.1e-153
KFCOGGID_01242 4.4e-261 KLT Domain of unknown function (DUF4032)
KFCOGGID_01243 8.6e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFCOGGID_01245 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KFCOGGID_01246 2.4e-27 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
KFCOGGID_01247 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
KFCOGGID_01248 5.3e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
KFCOGGID_01249 0.0 yjcE P Sodium/hydrogen exchanger family
KFCOGGID_01250 1.2e-145 ypfH S Phospholipase/Carboxylesterase
KFCOGGID_01251 1.1e-83 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KFCOGGID_01252 2.2e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
KFCOGGID_01253 6.8e-144 cobB2 K Sir2 family
KFCOGGID_01255 5.4e-160 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
KFCOGGID_01257 1.1e-45
KFCOGGID_01258 6.5e-96 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
KFCOGGID_01259 7.1e-64 S Protein of unknown function (DUF4235)
KFCOGGID_01260 7e-138 G Phosphoglycerate mutase family
KFCOGGID_01262 4.7e-188 K Psort location Cytoplasmic, score
KFCOGGID_01263 0.0 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
KFCOGGID_01264 0.0 dnaK O Heat shock 70 kDa protein
KFCOGGID_01265 2.8e-59 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFCOGGID_01266 1.4e-173 dnaJ1 O DnaJ molecular chaperone homology domain
KFCOGGID_01267 5.2e-87 hspR K transcriptional regulator, MerR family
KFCOGGID_01268 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR repeat-like domain
KFCOGGID_01269 0.0 3.2.1.18, 3.2.1.51 GH29,GH33 G BNR Asp-box repeat
KFCOGGID_01270 3.9e-133 S HAD hydrolase, family IA, variant 3
KFCOGGID_01272 2.7e-126 dedA S SNARE associated Golgi protein
KFCOGGID_01273 4.7e-169 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFCOGGID_01274 4.5e-32
KFCOGGID_01275 3.6e-130
KFCOGGID_01276 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFCOGGID_01277 2.9e-79 K Transcriptional regulator
KFCOGGID_01279 8.2e-271 xylR 5.3.1.12 G MFS/sugar transport protein
KFCOGGID_01280 5.9e-185 tatD L TatD related DNase
KFCOGGID_01281 0.0 kup P Transport of potassium into the cell
KFCOGGID_01282 3e-164 S Glutamine amidotransferase domain
KFCOGGID_01283 4.6e-137 T HD domain
KFCOGGID_01284 5.6e-186 V ABC transporter
KFCOGGID_01285 1.1e-246 V ABC transporter permease
KFCOGGID_01286 0.0 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
KFCOGGID_01287 0.0 S Psort location Cytoplasmic, score 8.87
KFCOGGID_01288 1.9e-164 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KFCOGGID_01289 8.7e-27 thiS 2.8.1.10 H ThiS family
KFCOGGID_01291 2.9e-162
KFCOGGID_01292 2.7e-71
KFCOGGID_01293 2e-208 S Glycosyltransferase, group 2 family protein
KFCOGGID_01294 2.5e-201 L Transposase, Mutator family
KFCOGGID_01295 5.7e-29 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
KFCOGGID_01296 1.7e-45 cbiM P PDGLE domain
KFCOGGID_01297 2.5e-90
KFCOGGID_01298 2.2e-201 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
KFCOGGID_01299 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFCOGGID_01300 2.4e-96 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFCOGGID_01302 2.6e-152 cpaE D bacterial-type flagellum organization
KFCOGGID_01303 3.4e-191 cpaF U Type II IV secretion system protein
KFCOGGID_01304 5.7e-121 U Type ii secretion system
KFCOGGID_01305 1.7e-15 gspF NU Type II secretion system (T2SS), protein F
KFCOGGID_01306 3.2e-15 gspF NU Type II secretion system (T2SS), protein F
KFCOGGID_01307 4.2e-41 S Protein of unknown function (DUF4244)
KFCOGGID_01308 3.1e-57 S TIGRFAM helicase secretion neighborhood TadE-like protein
KFCOGGID_01309 3.2e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
KFCOGGID_01310 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
KFCOGGID_01311 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFCOGGID_01312 1.8e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
KFCOGGID_01313 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
KFCOGGID_01315 1.7e-212 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFCOGGID_01316 1.7e-116
KFCOGGID_01317 2.3e-284 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KFCOGGID_01318 2.3e-15 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KFCOGGID_01319 3.5e-279 S Calcineurin-like phosphoesterase
KFCOGGID_01320 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFCOGGID_01321 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KFCOGGID_01322 1.2e-232 glf 5.4.99.9 M UDP-galactopyranose mutase
KFCOGGID_01323 1.8e-121 yplQ S Haemolysin-III related
KFCOGGID_01324 0.0 vpr M PA domain
KFCOGGID_01325 1.5e-114 3.6.1.27 I PAP2 superfamily
KFCOGGID_01326 1.4e-57 3.6.1.27 I PAP2 superfamily
KFCOGGID_01327 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFCOGGID_01328 4.8e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFCOGGID_01329 6.3e-213 holB 2.7.7.7 L DNA polymerase III
KFCOGGID_01330 4.4e-200 K helix_turn _helix lactose operon repressor
KFCOGGID_01331 5e-38 ptsH G PTS HPr component phosphorylation site
KFCOGGID_01332 3.6e-291 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFCOGGID_01333 1.4e-88 S Fic/DOC family
KFCOGGID_01334 7.1e-200 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
KFCOGGID_01335 1.2e-20 L Transposase and inactivated derivatives IS30 family
KFCOGGID_01336 3.2e-85 pin L Resolvase, N terminal domain
KFCOGGID_01337 1.9e-13
KFCOGGID_01338 1.3e-115 S AIPR protein
KFCOGGID_01340 1e-94 L protein secretion by the type IV secretion system
KFCOGGID_01341 1.3e-125 L Integrase core domain
KFCOGGID_01342 4.4e-35 L Psort location Cytoplasmic, score 8.87
KFCOGGID_01343 5.1e-113 K WHG domain
KFCOGGID_01344 5e-111 pptA 6.3.2.14 Q 4'-phosphopantetheinyl transferase superfamily
KFCOGGID_01345 3e-251 L Phage integrase family
KFCOGGID_01346 2.4e-85
KFCOGGID_01347 3.1e-276
KFCOGGID_01348 7e-46 K Helix-turn-helix XRE-family like proteins
KFCOGGID_01349 1.9e-53
KFCOGGID_01350 1.1e-12
KFCOGGID_01351 2.7e-86
KFCOGGID_01353 1.9e-24 M Belongs to the glycosyl hydrolase 30 family
KFCOGGID_01354 3e-80 M Belongs to the glycosyl hydrolase 30 family
KFCOGGID_01355 6.3e-190 1.1.1.65 C Aldo/keto reductase family
KFCOGGID_01356 3.2e-43 S Protein of unknown function (DUF1778)
KFCOGGID_01357 3.5e-41 ydgJ K helix_turn_helix multiple antibiotic resistance protein
KFCOGGID_01358 0.0 lmrA1 V ABC transporter, ATP-binding protein
KFCOGGID_01359 0.0 lmrA2 V ABC transporter transmembrane region
KFCOGGID_01361 0.0 3.2.1.51 GH95 G Glycosyl hydrolase family 65, N-terminal domain
KFCOGGID_01362 1.3e-107 S Phosphatidylethanolamine-binding protein
KFCOGGID_01363 0.0 pepD E Peptidase family C69
KFCOGGID_01364 6.2e-288 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
KFCOGGID_01365 1.3e-62 S Macrophage migration inhibitory factor (MIF)
KFCOGGID_01366 6.8e-98 S GtrA-like protein
KFCOGGID_01367 1.1e-262 EGP Major facilitator Superfamily
KFCOGGID_01368 1.1e-124 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
KFCOGGID_01369 7e-143
KFCOGGID_01370 3.2e-136 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
KFCOGGID_01371 8.6e-201 P NMT1/THI5 like
KFCOGGID_01372 1.9e-121 S HAD hydrolase, family IA, variant 3
KFCOGGID_01374 9.8e-277 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFCOGGID_01375 3.7e-96 S Domain of unknown function (DUF4143)
KFCOGGID_01376 3.6e-64 S Domain of unknown function (DUF4143)
KFCOGGID_01379 1.3e-251 S Calcineurin-like phosphoesterase
KFCOGGID_01380 2.8e-138 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
KFCOGGID_01381 2.2e-273 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFCOGGID_01382 3.8e-133 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFCOGGID_01383 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
KFCOGGID_01385 5.1e-180 S CAAX protease self-immunity
KFCOGGID_01386 8.9e-220 pyrD 1.3.1.14 F Dihydroorotate dehydrogenase
KFCOGGID_01387 9.8e-255 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFCOGGID_01388 1.7e-202 G Transmembrane secretion effector
KFCOGGID_01389 8.7e-133 K Bacterial regulatory proteins, tetR family
KFCOGGID_01390 1.1e-127
KFCOGGID_01391 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFCOGGID_01392 6.1e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KFCOGGID_01393 2.8e-166 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
KFCOGGID_01394 4.1e-187
KFCOGGID_01395 7.9e-180
KFCOGGID_01396 5e-163 trxA2 O Tetratricopeptide repeat
KFCOGGID_01397 2.8e-119 cyaA 4.6.1.1 S CYTH
KFCOGGID_01399 1.8e-184 K Bacterial regulatory proteins, lacI family
KFCOGGID_01400 1.6e-17 4.2.1.68 M carboxylic acid catabolic process
KFCOGGID_01401 3.2e-39 4.2.1.68 M Enolase C-terminal domain-like
KFCOGGID_01402 6.8e-164 IQ KR domain
KFCOGGID_01404 0.0 gnpA 2.4.1.211 S Lacto-N-biose phosphorylase C-terminal domain
KFCOGGID_01405 5.2e-63 psp1 3.5.99.10 J Endoribonuclease L-PSP
KFCOGGID_01406 2.3e-181 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KFCOGGID_01407 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KFCOGGID_01408 1.4e-303 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KFCOGGID_01409 1.9e-81 2.7.1.208 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
KFCOGGID_01410 2.9e-290 nagE 2.7.1.193, 2.7.1.199 G phosphotransferase system, EIIB
KFCOGGID_01411 8.8e-240 hom 1.1.1.3 E Homoserine dehydrogenase
KFCOGGID_01412 5.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KFCOGGID_01413 7.5e-277 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
KFCOGGID_01414 5.8e-67
KFCOGGID_01415 2.1e-58
KFCOGGID_01416 2.1e-163 V ATPases associated with a variety of cellular activities
KFCOGGID_01417 3.3e-256 V Efflux ABC transporter, permease protein
KFCOGGID_01418 8.4e-168 mdcF S Transporter, auxin efflux carrier (AEC) family protein
KFCOGGID_01419 3.2e-239 dapE 3.5.1.18 E Peptidase dimerisation domain
KFCOGGID_01420 0.0 rne 3.1.26.12 J Ribonuclease E/G family
KFCOGGID_01421 3.2e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
KFCOGGID_01422 3.1e-40 rpmA J Ribosomal L27 protein
KFCOGGID_01423 1.2e-185 K Psort location Cytoplasmic, score
KFCOGGID_01424 3.1e-298 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFCOGGID_01425 4.1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KFCOGGID_01426 4e-231 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
KFCOGGID_01428 2.1e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KFCOGGID_01429 3.6e-109 nusG K Participates in transcription elongation, termination and antitermination
KFCOGGID_01430 1.4e-172 plsC2 2.3.1.51 I Phosphate acyltransferases
KFCOGGID_01431 2.5e-178 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
KFCOGGID_01432 2.2e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KFCOGGID_01433 8.3e-201 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
KFCOGGID_01434 0.0 3.2.1.97 GH101 G Glycosyl hydrolase 101 beta sandwich domain
KFCOGGID_01435 6.9e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFCOGGID_01436 0.0 ftsK 2.7.11.1, 2.7.7.7, 3.4.21.110, 4.2.1.2 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFCOGGID_01437 6.2e-115
KFCOGGID_01439 5.9e-172 T Pfam Adenylate and Guanylate cyclase catalytic domain
KFCOGGID_01440 6.1e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
KFCOGGID_01441 1.1e-79 ssb1 L Single-stranded DNA-binding protein
KFCOGGID_01442 2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFCOGGID_01443 1.5e-69 rplI J Binds to the 23S rRNA
KFCOGGID_01444 2.4e-16 S Parallel beta-helix repeats
KFCOGGID_01445 8.5e-46 S Parallel beta-helix repeats
KFCOGGID_01446 6.5e-69 E Domain of unknown function (DUF5011)
KFCOGGID_01448 6.4e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
KFCOGGID_01449 8.7e-129 M Protein of unknown function (DUF3152)
KFCOGGID_01450 1.1e-194 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFCOGGID_01451 8.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFCOGGID_01452 3.6e-53 acyP 3.6.1.7 C Acylphosphatase
KFCOGGID_01453 0.0 inlJ M domain protein
KFCOGGID_01454 7.1e-276 M LPXTG cell wall anchor motif
KFCOGGID_01455 1.6e-216 3.4.22.70 M Sortase family
KFCOGGID_01456 4e-88 S Domain of unknown function (DUF4854)
KFCOGGID_01457 4.2e-155 fahA Q Fumarylacetoacetate (FAA) hydrolase family
KFCOGGID_01458 1.9e-30 2.1.1.72 S Protein conserved in bacteria
KFCOGGID_01459 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
KFCOGGID_01460 6.1e-132 M Mechanosensitive ion channel
KFCOGGID_01461 1.7e-119 K Bacterial regulatory proteins, tetR family
KFCOGGID_01462 2.9e-240 MA20_36090 S Psort location Cytoplasmic, score 8.87
KFCOGGID_01463 1.2e-232 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
KFCOGGID_01464 2.1e-65
KFCOGGID_01466 1.3e-43 K Transcriptional regulator
KFCOGGID_01467 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KFCOGGID_01474 1e-98 tam 2.1.1.144, 2.1.1.197 S Methyltransferase domain
KFCOGGID_01475 1.1e-236 K Helix-turn-helix XRE-family like proteins
KFCOGGID_01476 1.8e-53 relB L RelB antitoxin
KFCOGGID_01477 5e-60 T Toxic component of a toxin-antitoxin (TA) module
KFCOGGID_01478 4.2e-130 K helix_turn_helix, mercury resistance
KFCOGGID_01479 1.6e-241 yxiO S Vacuole effluxer Atg22 like
KFCOGGID_01481 1.1e-200 yegV G pfkB family carbohydrate kinase
KFCOGGID_01482 1.4e-29 rpmB J Ribosomal L28 family
KFCOGGID_01483 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
KFCOGGID_01484 1.3e-219 steT E amino acid
KFCOGGID_01487 0.0
KFCOGGID_01488 1e-245 U Sodium:dicarboxylate symporter family
KFCOGGID_01489 6.8e-122 rsmD 2.1.1.171 L Conserved hypothetical protein 95
KFCOGGID_01490 1e-105 XK27_02070 S Nitroreductase family
KFCOGGID_01491 8.9e-83 hsp20 O Hsp20/alpha crystallin family
KFCOGGID_01492 1.1e-168 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KFCOGGID_01493 1.3e-108 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFCOGGID_01494 1.8e-34 CP_0960 S Belongs to the UPF0109 family
KFCOGGID_01495 1e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KFCOGGID_01497 3.8e-295 ydfD EK Alanine-glyoxylate amino-transferase
KFCOGGID_01498 2.2e-93 argO S LysE type translocator
KFCOGGID_01499 1.8e-220 S Endonuclease/Exonuclease/phosphatase family
KFCOGGID_01500 1.6e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFCOGGID_01501 1.4e-164 P Cation efflux family
KFCOGGID_01502 4.8e-120 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFCOGGID_01503 4.1e-170 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFCOGGID_01504 1.9e-135 guaA1 6.3.5.2 F Peptidase C26
KFCOGGID_01505 0.0 yjjK S ABC transporter
KFCOGGID_01506 2e-58 S Protein of unknown function (DUF3039)
KFCOGGID_01507 1.2e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFCOGGID_01508 1.4e-106
KFCOGGID_01509 1e-113 yceD S Uncharacterized ACR, COG1399
KFCOGGID_01510 2.3e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KFCOGGID_01511 6.1e-140 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KFCOGGID_01512 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
KFCOGGID_01513 7.6e-92 ilvN 2.2.1.6 E ACT domain
KFCOGGID_01516 5.7e-247 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KFCOGGID_01517 2.1e-134 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFCOGGID_01518 1.8e-116 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFCOGGID_01519 6.4e-174 S Auxin Efflux Carrier
KFCOGGID_01522 0.0 pgi 5.3.1.9 G Belongs to the GPI family
KFCOGGID_01523 1.5e-190
KFCOGGID_01525 6.9e-201
KFCOGGID_01527 5.5e-122 mgtC S MgtC family
KFCOGGID_01528 0.0 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
KFCOGGID_01529 2.6e-34 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
KFCOGGID_01530 2.4e-24 mgtA 3.6.3.2 P Cation transporting ATPase, C-terminus
KFCOGGID_01531 4.3e-275 abcT3 P ATPases associated with a variety of cellular activities
KFCOGGID_01532 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
KFCOGGID_01534 3.2e-30 K Putative sugar-binding domain
KFCOGGID_01535 1.5e-96 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
KFCOGGID_01536 5.6e-62 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KFCOGGID_01537 4.4e-157 lepB 3.4.21.89 U Belongs to the peptidase S26 family
KFCOGGID_01538 2.5e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFCOGGID_01539 3.1e-209 K helix_turn _helix lactose operon repressor
KFCOGGID_01540 1.1e-08 tnp7109-21 L Integrase core domain
KFCOGGID_01541 0.0 fadD 6.2.1.3 I AMP-binding enzyme
KFCOGGID_01542 6.9e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KFCOGGID_01543 4.8e-111 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KFCOGGID_01546 1.3e-300 G Glycosyl hydrolases family 43
KFCOGGID_01547 5.5e-201 K helix_turn _helix lactose operon repressor
KFCOGGID_01548 2.4e-11 E Domain of unknown function (DUF5011)
KFCOGGID_01549 2.9e-170 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
KFCOGGID_01550 4.3e-121 L Protein of unknown function (DUF1524)
KFCOGGID_01551 5.5e-226 mntH P H( )-stimulated, divalent metal cation uptake system
KFCOGGID_01552 1.8e-306 EGP Major facilitator Superfamily
KFCOGGID_01553 3.2e-228
KFCOGGID_01554 1.3e-179 S G5
KFCOGGID_01555 1.5e-59 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
KFCOGGID_01556 3.4e-117 F Domain of unknown function (DUF4916)
KFCOGGID_01557 1.7e-159 mhpC I Alpha/beta hydrolase family
KFCOGGID_01558 2.4e-08 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
KFCOGGID_01559 0.0 enhA_2 S L,D-transpeptidase catalytic domain
KFCOGGID_01560 3.7e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
KFCOGGID_01561 9e-240 S Uncharacterized conserved protein (DUF2183)
KFCOGGID_01562 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
KFCOGGID_01563 2.4e-192 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KFCOGGID_01564 9.9e-120 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
KFCOGGID_01565 1.6e-134 glxR K helix_turn_helix, cAMP Regulatory protein
KFCOGGID_01566 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
KFCOGGID_01567 1.9e-219 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
KFCOGGID_01568 6.7e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
KFCOGGID_01569 3.1e-139 glpR K DeoR C terminal sensor domain
KFCOGGID_01570 7.3e-252 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
KFCOGGID_01571 9.9e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
KFCOGGID_01572 8.6e-243 EGP Sugar (and other) transporter
KFCOGGID_01573 4.2e-43 gcvR T Belongs to the UPF0237 family
KFCOGGID_01574 4.7e-252 S UPF0210 protein
KFCOGGID_01575 1.9e-195 S Membrane
KFCOGGID_01576 2.3e-25 S Membrane
KFCOGGID_01577 2.4e-121 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KFCOGGID_01578 2.8e-66 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
KFCOGGID_01579 7.6e-37 exsH 3.2.1.178, 3.2.1.18, 3.2.1.52 GH16,GH20,GH33 G Putative cell wall binding repeat
KFCOGGID_01580 5.6e-183 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
KFCOGGID_01581 8.6e-103
KFCOGGID_01582 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFCOGGID_01583 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFCOGGID_01584 6.5e-96 T Forkhead associated domain
KFCOGGID_01585 1.1e-67 B Belongs to the OprB family
KFCOGGID_01586 3.7e-165 3.1.3.16 T Sigma factor PP2C-like phosphatases
KFCOGGID_01587 0.0 E Transglutaminase-like superfamily
KFCOGGID_01588 3.5e-228 S Protein of unknown function DUF58
KFCOGGID_01589 2.8e-220 S ATPase family associated with various cellular activities (AAA)
KFCOGGID_01590 0.0 S Fibronectin type 3 domain
KFCOGGID_01591 2.2e-268 KLT Protein tyrosine kinase
KFCOGGID_01592 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
KFCOGGID_01593 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
KFCOGGID_01594 2.6e-147 K -acetyltransferase
KFCOGGID_01595 1.7e-249 G Major Facilitator Superfamily
KFCOGGID_01596 2.1e-41 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KFCOGGID_01597 6.4e-24 relB L RelB antitoxin
KFCOGGID_01598 2.8e-57 L Transposase
KFCOGGID_01599 1e-132 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KFCOGGID_01600 1.9e-161 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFCOGGID_01601 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFCOGGID_01602 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
KFCOGGID_01603 9.7e-252 O Subtilase family
KFCOGGID_01604 5.4e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFCOGGID_01605 2.2e-122 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KFCOGGID_01606 1.4e-270 S zinc finger
KFCOGGID_01607 1.5e-112 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KFCOGGID_01608 2.9e-229 aspB E Aminotransferase class-V
KFCOGGID_01609 3.3e-95 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KFCOGGID_01610 2.3e-37 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
KFCOGGID_01611 1e-131 tmp1 S Domain of unknown function (DUF4391)
KFCOGGID_01612 2.6e-149 moeB 2.7.7.80 H ThiF family
KFCOGGID_01613 1.6e-255 cdr OP Sulfurtransferase TusA
KFCOGGID_01614 1.2e-180 iunH1 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
KFCOGGID_01617 6.2e-202 S Endonuclease/Exonuclease/phosphatase family
KFCOGGID_01618 7.8e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KFCOGGID_01619 8.5e-273 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KFCOGGID_01620 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
KFCOGGID_01621 2.5e-140 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KFCOGGID_01624 5.2e-132 dam 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KFCOGGID_01625 1.4e-72
KFCOGGID_01626 4.8e-11
KFCOGGID_01627 4.1e-165 L Helix-turn-helix domain
KFCOGGID_01628 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
KFCOGGID_01629 3.4e-166
KFCOGGID_01630 2.6e-257 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
KFCOGGID_01631 0.0 plyA3 3.2.1.18 GH33 M Parallel beta-helix repeats
KFCOGGID_01633 5.8e-89 K MarR family
KFCOGGID_01634 0.0 V ABC transporter, ATP-binding protein
KFCOGGID_01635 0.0 V ABC transporter transmembrane region
KFCOGGID_01636 1.4e-168 S Patatin-like phospholipase
KFCOGGID_01637 3.9e-153 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KFCOGGID_01638 2.8e-168 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
KFCOGGID_01639 7.6e-115 S Vitamin K epoxide reductase
KFCOGGID_01640 1.5e-166 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
KFCOGGID_01641 3.7e-29 S Protein of unknown function (DUF3107)
KFCOGGID_01642 8e-237 mphA S Aminoglycoside phosphotransferase
KFCOGGID_01643 1.4e-18 uvrD2 3.6.4.12 L DNA helicase
KFCOGGID_01644 3.2e-253 uvrD2 3.6.4.12 L DNA helicase
KFCOGGID_01645 4.6e-288 S Zincin-like metallopeptidase
KFCOGGID_01646 1.4e-150 lon T Belongs to the peptidase S16 family
KFCOGGID_01647 5.5e-66 S Protein of unknown function (DUF3052)
KFCOGGID_01648 2.6e-194 K helix_turn _helix lactose operon repressor
KFCOGGID_01649 9.5e-201 L Transposase, Mutator family
KFCOGGID_01651 3.3e-59 S Thiamine-binding protein
KFCOGGID_01652 9.2e-164 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KFCOGGID_01653 6.9e-231 O AAA domain (Cdc48 subfamily)
KFCOGGID_01654 1.3e-84
KFCOGGID_01655 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFCOGGID_01656 6.1e-160 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KFCOGGID_01657 0.0 lacZ 3.2.1.23 G Domain of unknown function (DUF4982)
KFCOGGID_01658 4.5e-68 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KFCOGGID_01659 2.5e-211 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
KFCOGGID_01660 8e-246 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFCOGGID_01661 7.3e-231 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFCOGGID_01662 4.3e-80 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KFCOGGID_01663 2.1e-42 yggT S YGGT family
KFCOGGID_01664 9.7e-90 3.1.21.3 V DivIVA protein
KFCOGGID_01665 4e-103 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFCOGGID_01666 1.3e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
KFCOGGID_01668 6e-63
KFCOGGID_01669 5.2e-147 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
KFCOGGID_01670 8.2e-202 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KFCOGGID_01671 8.7e-201 ftsE D Cell division ATP-binding protein FtsE
KFCOGGID_01672 2.4e-159 ftsX D Part of the ABC transporter FtsEX involved in cellular division
KFCOGGID_01673 2.5e-163 usp 3.5.1.28 CBM50 D CHAP domain protein
KFCOGGID_01674 3e-76 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
KFCOGGID_01675 5.6e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
KFCOGGID_01676 1.1e-23
KFCOGGID_01678 1.6e-203 2.7.11.1 NU Tfp pilus assembly protein FimV
KFCOGGID_01679 1.5e-222 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KFCOGGID_01680 3.9e-235 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KFCOGGID_01681 5e-293 I acetylesterase activity
KFCOGGID_01682 9.2e-144 recO L Involved in DNA repair and RecF pathway recombination
KFCOGGID_01683 1.8e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFCOGGID_01684 9.6e-191 ywqG S Domain of unknown function (DUF1963)
KFCOGGID_01685 3e-39 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
KFCOGGID_01686 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
KFCOGGID_01687 7.3e-85 S zinc-ribbon domain
KFCOGGID_01688 1.6e-46 yhbY J CRS1_YhbY
KFCOGGID_01689 0.0 4.2.1.53 S MCRA family
KFCOGGID_01692 8.9e-203 K WYL domain
KFCOGGID_01693 6.5e-156 yvgN 1.1.1.346 S Aldo/keto reductase family
KFCOGGID_01694 5.8e-174 dkgA 1.1.1.346 C Aldo/keto reductase family
KFCOGGID_01695 1.2e-76 yneG S Domain of unknown function (DUF4186)
KFCOGGID_01697 3.9e-07 pbpB 2.7.11.1, 3.4.16.4 S PASTA domain
KFCOGGID_01698 6.2e-182 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_01699 2.1e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFCOGGID_01700 4.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFCOGGID_01701 3.2e-112 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
KFCOGGID_01702 4.2e-111
KFCOGGID_01703 7e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFCOGGID_01704 1.7e-131 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
KFCOGGID_01705 4.9e-284 S Uncharacterized protein conserved in bacteria (DUF2252)
KFCOGGID_01706 2.1e-265 glnA2 6.3.1.2 E glutamine synthetase
KFCOGGID_01707 6.5e-246 S Domain of unknown function (DUF5067)
KFCOGGID_01708 8.4e-177 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KFCOGGID_01709 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
KFCOGGID_01710 3.1e-121 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
KFCOGGID_01711 5.6e-37
KFCOGGID_01712 1.2e-105
KFCOGGID_01713 2.1e-272 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFCOGGID_01714 4.6e-177 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
KFCOGGID_01715 6e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFCOGGID_01716 7.5e-129 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFCOGGID_01717 3.2e-49 M Lysin motif
KFCOGGID_01718 8.8e-83 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFCOGGID_01719 2.9e-229 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
KFCOGGID_01720 0.0 L DNA helicase
KFCOGGID_01721 1.3e-90 mraZ K Belongs to the MraZ family
KFCOGGID_01722 7.8e-189 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KFCOGGID_01723 4.1e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFCOGGID_01724 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
KFCOGGID_01725 5.8e-33 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFCOGGID_01726 7.7e-138 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFCOGGID_01727 2.6e-283 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KFCOGGID_01728 3.4e-166 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFCOGGID_01729 3.5e-266 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFCOGGID_01730 4e-224 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
KFCOGGID_01731 6.5e-218 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFCOGGID_01732 2.1e-280 murC 6.3.2.8 M Belongs to the MurCDEF family
KFCOGGID_01733 1.3e-158 ftsQ 6.3.2.4 D Cell division protein FtsQ
KFCOGGID_01734 4.6e-35
KFCOGGID_01736 1.7e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KFCOGGID_01737 5.8e-236 G Major Facilitator Superfamily
KFCOGGID_01738 1.9e-169 2.7.1.4 G pfkB family carbohydrate kinase
KFCOGGID_01739 4e-223 GK ROK family
KFCOGGID_01740 2.9e-131 cutC P Participates in the control of copper homeostasis
KFCOGGID_01741 8.9e-209 GK ROK family
KFCOGGID_01742 6.6e-153 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KFCOGGID_01743 6.2e-243 nagA 3.5.1.25 G Amidohydrolase family
KFCOGGID_01744 1.7e-304 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
KFCOGGID_01745 2e-184 dppB EP Binding-protein-dependent transport system inner membrane component
KFCOGGID_01746 8.7e-191 dppC EP Binding-protein-dependent transport system inner membrane component
KFCOGGID_01747 0.0 P Belongs to the ABC transporter superfamily
KFCOGGID_01748 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
KFCOGGID_01749 9.6e-97 3.6.1.55 F NUDIX domain
KFCOGGID_01751 7.6e-70 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KFCOGGID_01752 1e-205 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
KFCOGGID_01753 0.0 smc D Required for chromosome condensation and partitioning
KFCOGGID_01754 7.4e-129 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
KFCOGGID_01755 9.5e-244 yxbA 6.3.1.12 S ATP-grasp
KFCOGGID_01756 1.3e-229 2.6.1.33 M DegT/DnrJ/EryC1/StrS aminotransferase family
KFCOGGID_01757 5.7e-191 V Acetyltransferase (GNAT) domain
KFCOGGID_01758 1e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFCOGGID_01759 2.1e-114 sigH K Belongs to the sigma-70 factor family. ECF subfamily
KFCOGGID_01760 4.9e-63
KFCOGGID_01761 9.1e-194 galM 5.1.3.3 G Aldose 1-epimerase
KFCOGGID_01762 5.5e-178 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFCOGGID_01764 7.1e-92 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFCOGGID_01765 1e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KFCOGGID_01766 4e-133 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
KFCOGGID_01767 2.3e-08 S Spermine/spermidine synthase domain
KFCOGGID_01768 7.1e-08 S Spermine/spermidine synthase domain
KFCOGGID_01769 1.4e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFCOGGID_01770 2.1e-25 rpmI J Ribosomal protein L35
KFCOGGID_01771 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFCOGGID_01772 2.9e-179 xerD D recombinase XerD
KFCOGGID_01773 2.7e-151 soj D CobQ CobB MinD ParA nucleotide binding domain protein
KFCOGGID_01774 1.4e-150 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFCOGGID_01775 6e-112 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFCOGGID_01776 8.6e-150 nrtR 3.6.1.55 F NUDIX hydrolase
KFCOGGID_01777 1.8e-250 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFCOGGID_01778 0.0 nadB 1.3.5.4, 1.4.3.16, 2.4.2.19 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KFCOGGID_01779 1.3e-162 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, N-terminal domain
KFCOGGID_01780 9.8e-236 iscS1 2.8.1.7 E Aminotransferase class-V
KFCOGGID_01781 0.0 typA T Elongation factor G C-terminus
KFCOGGID_01782 4.1e-79
KFCOGGID_01783 5.5e-197 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
KFCOGGID_01784 4.1e-192 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
KFCOGGID_01785 7.3e-42
KFCOGGID_01786 1.6e-185 xerC D Belongs to the 'phage' integrase family. XerC subfamily
KFCOGGID_01787 1.5e-175 appB EP Binding-protein-dependent transport system inner membrane component
KFCOGGID_01788 1.3e-165 dppC EP N-terminal TM domain of oligopeptide transport permease C
KFCOGGID_01789 0.0 oppD P Belongs to the ABC transporter superfamily
KFCOGGID_01790 0.0 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
KFCOGGID_01791 3.1e-275 pepC 3.4.22.40 E Peptidase C1-like family
KFCOGGID_01792 1.4e-169 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
KFCOGGID_01793 3e-137 S Protein of unknown function (DUF3710)
KFCOGGID_01794 7.5e-130 S Protein of unknown function (DUF3159)
KFCOGGID_01795 9.3e-247 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFCOGGID_01796 2.3e-110
KFCOGGID_01797 0.0 ctpE P E1-E2 ATPase
KFCOGGID_01798 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KFCOGGID_01800 1.1e-166 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
KFCOGGID_01801 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
KFCOGGID_01802 1.1e-53 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KFCOGGID_01803 8.5e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFCOGGID_01804 9.7e-70 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFCOGGID_01805 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFCOGGID_01806 1.2e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KFCOGGID_01807 2.1e-182 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFCOGGID_01808 1.1e-136 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
KFCOGGID_01809 0.0 arc O AAA ATPase forming ring-shaped complexes
KFCOGGID_01810 0.0 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
KFCOGGID_01811 2e-157 hisN 3.1.3.25 G Inositol monophosphatase family
KFCOGGID_01812 9.2e-11 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
KFCOGGID_01813 5e-276 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KFCOGGID_01814 8.1e-42 hup L Belongs to the bacterial histone-like protein family
KFCOGGID_01815 0.0 S Lysylphosphatidylglycerol synthase TM region
KFCOGGID_01816 8.1e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
KFCOGGID_01817 8.3e-290 S PGAP1-like protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)