ORF_ID e_value Gene_name EC_number CAZy COGs Description
NIDDKIGC_00001 2.1e-55 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIDDKIGC_00002 4.7e-218 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIDDKIGC_00003 4e-35 lsgC M Glycosyl transferases group 1
NIDDKIGC_00004 1.6e-39 lsgC M Glycosyl transferases group 1
NIDDKIGC_00005 2.3e-98 lsgC M Glycosyl transferases group 1
NIDDKIGC_00006 5.6e-21 S Protein of unknown function (DUF2929)
NIDDKIGC_00007 2.4e-20 K Cro/C1-type HTH DNA-binding domain
NIDDKIGC_00009 8.8e-37 S response to antibiotic
NIDDKIGC_00010 4.6e-15 S zinc-ribbon domain
NIDDKIGC_00011 1.1e-16 S zinc-ribbon domain
NIDDKIGC_00013 5.7e-20
NIDDKIGC_00014 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIDDKIGC_00015 1e-76 uspA T universal stress protein
NIDDKIGC_00016 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
NIDDKIGC_00017 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NIDDKIGC_00018 4e-60
NIDDKIGC_00019 1.7e-73
NIDDKIGC_00020 5e-82 yybC S Protein of unknown function (DUF2798)
NIDDKIGC_00021 6.3e-45
NIDDKIGC_00022 5.2e-47
NIDDKIGC_00023 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NIDDKIGC_00024 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIDDKIGC_00025 8.4e-145 yjfP S Dienelactone hydrolase family
NIDDKIGC_00026 5.4e-68
NIDDKIGC_00027 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_00028 9.3e-278 L Transposase
NIDDKIGC_00029 5.9e-48
NIDDKIGC_00030 5.6e-56
NIDDKIGC_00032 8.7e-164
NIDDKIGC_00033 1.3e-72 K Transcriptional regulator
NIDDKIGC_00034 0.0 pepF2 E Oligopeptidase F
NIDDKIGC_00035 7e-175 D Alpha beta
NIDDKIGC_00036 1.2e-45 S Enterocin A Immunity
NIDDKIGC_00037 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
NIDDKIGC_00038 5.1e-125 skfE V ABC transporter
NIDDKIGC_00039 2.7e-132
NIDDKIGC_00040 3.7e-107 pncA Q Isochorismatase family
NIDDKIGC_00041 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NIDDKIGC_00042 0.0 yjcE P Sodium proton antiporter
NIDDKIGC_00043 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
NIDDKIGC_00044 1.3e-176 S Oxidoreductase family, NAD-binding Rossmann fold
NIDDKIGC_00045 2.2e-114 K Helix-turn-helix domain, rpiR family
NIDDKIGC_00046 2.3e-157 ccpB 5.1.1.1 K lacI family
NIDDKIGC_00047 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_00048 1.7e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIDDKIGC_00049 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
NIDDKIGC_00050 2.5e-98 drgA C Nitroreductase family
NIDDKIGC_00051 3.6e-168 S Polyphosphate kinase 2 (PPK2)
NIDDKIGC_00052 1.1e-181 3.6.4.13 S domain, Protein
NIDDKIGC_00053 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_00054 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NIDDKIGC_00055 0.0 glpQ 3.1.4.46 C phosphodiesterase
NIDDKIGC_00056 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIDDKIGC_00057 3.9e-75 yjcF S Acetyltransferase (GNAT) domain
NIDDKIGC_00058 3.9e-285 M domain protein
NIDDKIGC_00059 0.0 ydgH S MMPL family
NIDDKIGC_00060 3.2e-112 S Protein of unknown function (DUF1211)
NIDDKIGC_00061 3.7e-34
NIDDKIGC_00062 2.2e-184 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIDDKIGC_00063 8e-199 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NIDDKIGC_00064 8.6e-98 J glyoxalase III activity
NIDDKIGC_00065 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_00066 5.9e-91 rmeB K transcriptional regulator, MerR family
NIDDKIGC_00067 2.1e-55 S Domain of unknown function (DU1801)
NIDDKIGC_00068 1.7e-165 corA P CorA-like Mg2+ transporter protein
NIDDKIGC_00069 4.6e-216 ysaA V RDD family
NIDDKIGC_00070 8.5e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
NIDDKIGC_00071 3.6e-213 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NIDDKIGC_00072 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NIDDKIGC_00073 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NIDDKIGC_00074 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NIDDKIGC_00075 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NIDDKIGC_00076 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NIDDKIGC_00077 3.8e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NIDDKIGC_00078 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NIDDKIGC_00079 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
NIDDKIGC_00080 3.3e-200 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NIDDKIGC_00081 1.2e-84 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIDDKIGC_00082 4.8e-137 terC P membrane
NIDDKIGC_00083 2.7e-157 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
NIDDKIGC_00084 2.5e-258 npr 1.11.1.1 C NADH oxidase
NIDDKIGC_00085 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
NIDDKIGC_00086 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NIDDKIGC_00087 1.4e-176 XK27_08835 S ABC transporter
NIDDKIGC_00088 1.1e-164 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
NIDDKIGC_00089 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
NIDDKIGC_00090 1.2e-230 hom1 1.1.1.3 E Homoserine dehydrogenase
NIDDKIGC_00091 5e-162 degV S Uncharacterised protein, DegV family COG1307
NIDDKIGC_00092 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIDDKIGC_00093 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
NIDDKIGC_00094 5.1e-25
NIDDKIGC_00095 1.5e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NIDDKIGC_00096 2e-106 3.2.2.20 K acetyltransferase
NIDDKIGC_00097 7.8e-296 S ABC transporter, ATP-binding protein
NIDDKIGC_00098 4.7e-216 2.7.7.65 T diguanylate cyclase
NIDDKIGC_00099 5.1e-34
NIDDKIGC_00100 2e-35
NIDDKIGC_00101 6.6e-81 K AsnC family
NIDDKIGC_00102 1.3e-170 ykfC 3.4.14.13 M NlpC/P60 family
NIDDKIGC_00103 6.6e-159 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_00105 3.8e-23
NIDDKIGC_00106 4.6e-137 3.6.1.13, 3.6.1.55 F NUDIX domain
NIDDKIGC_00107 2.2e-213 yceI EGP Major facilitator Superfamily
NIDDKIGC_00108 4.2e-47
NIDDKIGC_00109 7.7e-92 S ECF-type riboflavin transporter, S component
NIDDKIGC_00111 1.5e-169 EG EamA-like transporter family
NIDDKIGC_00112 2.3e-38 gcvR T Belongs to the UPF0237 family
NIDDKIGC_00113 3e-243 XK27_08635 S UPF0210 protein
NIDDKIGC_00114 1.6e-134 K response regulator
NIDDKIGC_00115 2.9e-287 yclK 2.7.13.3 T Histidine kinase
NIDDKIGC_00116 1.2e-216 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
NIDDKIGC_00117 9.7e-155 glcU U sugar transport
NIDDKIGC_00118 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
NIDDKIGC_00119 6.8e-24
NIDDKIGC_00120 0.0 macB3 V ABC transporter, ATP-binding protein
NIDDKIGC_00121 2.9e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NIDDKIGC_00122 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
NIDDKIGC_00123 1.6e-16
NIDDKIGC_00124 1.9e-18
NIDDKIGC_00125 1.6e-16
NIDDKIGC_00126 1.6e-16
NIDDKIGC_00127 1.6e-16
NIDDKIGC_00128 5.2e-15
NIDDKIGC_00129 7.2e-17
NIDDKIGC_00130 2.7e-16
NIDDKIGC_00131 4.2e-308 M MucBP domain
NIDDKIGC_00132 0.0 bztC D nuclear chromosome segregation
NIDDKIGC_00133 7.3e-83 K MarR family
NIDDKIGC_00134 1.4e-43
NIDDKIGC_00135 2e-38
NIDDKIGC_00136 1.1e-225 sip L Belongs to the 'phage' integrase family
NIDDKIGC_00137 5.7e-14 K Cro/C1-type HTH DNA-binding domain
NIDDKIGC_00139 3.8e-08
NIDDKIGC_00140 2.3e-34
NIDDKIGC_00141 7e-147 L DNA replication protein
NIDDKIGC_00142 8.8e-220 S Virulence-associated protein E
NIDDKIGC_00143 2.2e-87
NIDDKIGC_00144 6.6e-27
NIDDKIGC_00145 7.3e-53 S head-tail joining protein
NIDDKIGC_00146 6.3e-69 L Phage-associated protein
NIDDKIGC_00147 1e-81 terS L overlaps another CDS with the same product name
NIDDKIGC_00148 0.0 terL S overlaps another CDS with the same product name
NIDDKIGC_00150 7.7e-205 S Phage portal protein
NIDDKIGC_00151 5.6e-278 S Caudovirus prohead serine protease
NIDDKIGC_00152 9.5e-40 S Phage gp6-like head-tail connector protein
NIDDKIGC_00153 1.1e-52
NIDDKIGC_00154 1.6e-45 gepA S Protein of unknown function (DUF4065)
NIDDKIGC_00155 4.3e-13
NIDDKIGC_00157 8.9e-30
NIDDKIGC_00159 4.3e-219 int L Belongs to the 'phage' integrase family
NIDDKIGC_00160 2.2e-115 K SIR2-like domain
NIDDKIGC_00165 3.1e-38 M Host cell surface-exposed lipoprotein
NIDDKIGC_00166 9.4e-10 E peptidase
NIDDKIGC_00167 1.3e-16 K sequence-specific DNA binding
NIDDKIGC_00172 1.3e-13 S Hypothetical protein (DUF2513)
NIDDKIGC_00173 1.5e-17 K Cro/C1-type HTH DNA-binding domain
NIDDKIGC_00177 4.5e-54
NIDDKIGC_00178 4.4e-86
NIDDKIGC_00180 6.4e-26
NIDDKIGC_00181 1.4e-12 S Domain of unknown function (DUF1508)
NIDDKIGC_00182 7.9e-72
NIDDKIGC_00183 4.9e-149 recT L RecT family
NIDDKIGC_00184 4e-136 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NIDDKIGC_00185 1.4e-30 3.1.3.16 L DnaD domain protein
NIDDKIGC_00186 1.3e-151 S IstB-like ATP binding protein
NIDDKIGC_00188 1.8e-61 ps308 K AntA/AntB antirepressor
NIDDKIGC_00189 9.6e-65
NIDDKIGC_00190 2.4e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
NIDDKIGC_00192 1.9e-80 arpU S Phage transcriptional regulator, ArpU family
NIDDKIGC_00195 2.1e-79
NIDDKIGC_00196 2.3e-10
NIDDKIGC_00197 4e-18
NIDDKIGC_00198 2e-29
NIDDKIGC_00200 4.8e-22 S Psort location Cytoplasmic, score
NIDDKIGC_00201 2.1e-64 S Terminase small subunit
NIDDKIGC_00202 1e-134 ps334 S Terminase-like family
NIDDKIGC_00203 5.7e-271 S Phage portal protein, SPP1 Gp6-like
NIDDKIGC_00204 1.8e-130 S Phage Mu protein F like protein
NIDDKIGC_00205 3.1e-60 S Domain of unknown function (DUF4355)
NIDDKIGC_00206 1.5e-43
NIDDKIGC_00207 3.3e-171 S Phage major capsid protein E
NIDDKIGC_00208 9.6e-51 S Phage gp6-like head-tail connector protein
NIDDKIGC_00209 1.3e-38
NIDDKIGC_00210 3.8e-55
NIDDKIGC_00211 2.6e-46
NIDDKIGC_00212 5.4e-97
NIDDKIGC_00213 6.9e-71 S Phage tail assembly chaperone protein, TAC
NIDDKIGC_00215 9.9e-250 D NLP P60 protein
NIDDKIGC_00217 3.6e-139 S Phage tail protein
NIDDKIGC_00218 2.3e-170 M Prophage endopeptidase tail
NIDDKIGC_00221 3.4e-82 S Calcineurin-like phosphoesterase
NIDDKIGC_00223 9e-169 M hydrolase, family 25
NIDDKIGC_00224 1.6e-48
NIDDKIGC_00225 1.1e-33 hol S Bacteriophage holin
NIDDKIGC_00226 1.8e-15
NIDDKIGC_00227 1.9e-65 K IrrE N-terminal-like domain
NIDDKIGC_00229 3.8e-135 yxkH G Polysaccharide deacetylase
NIDDKIGC_00230 3.3e-65 S Protein of unknown function (DUF1093)
NIDDKIGC_00231 0.0 ycfI V ABC transporter, ATP-binding protein
NIDDKIGC_00232 0.0 yfiC V ABC transporter
NIDDKIGC_00233 2.3e-123
NIDDKIGC_00234 1.9e-58
NIDDKIGC_00235 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NIDDKIGC_00236 1.4e-29
NIDDKIGC_00237 2e-191 ampC V Beta-lactamase
NIDDKIGC_00238 1.1e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
NIDDKIGC_00239 4.2e-135 cobQ S glutamine amidotransferase
NIDDKIGC_00240 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NIDDKIGC_00241 9.3e-109 tdk 2.7.1.21 F thymidine kinase
NIDDKIGC_00242 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NIDDKIGC_00243 1.1e-158 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NIDDKIGC_00244 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NIDDKIGC_00245 8.3e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NIDDKIGC_00246 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NIDDKIGC_00247 5e-232 pyrP F Permease
NIDDKIGC_00248 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NIDDKIGC_00249 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIDDKIGC_00250 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NIDDKIGC_00251 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NIDDKIGC_00252 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NIDDKIGC_00253 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NIDDKIGC_00254 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NIDDKIGC_00255 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NIDDKIGC_00256 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIDDKIGC_00257 2.1e-102 J Acetyltransferase (GNAT) domain
NIDDKIGC_00258 2.7e-180 mbl D Cell shape determining protein MreB Mrl
NIDDKIGC_00259 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NIDDKIGC_00260 3.3e-33 S Protein of unknown function (DUF2969)
NIDDKIGC_00261 9.3e-220 rodA D Belongs to the SEDS family
NIDDKIGC_00262 3.6e-48 gcsH2 E glycine cleavage
NIDDKIGC_00263 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIDDKIGC_00264 1.4e-111 metI U ABC transporter permease
NIDDKIGC_00265 1.1e-147 metQ M Belongs to the nlpA lipoprotein family
NIDDKIGC_00266 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
NIDDKIGC_00267 1.6e-177 S Protein of unknown function (DUF2785)
NIDDKIGC_00268 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIDDKIGC_00269 1.6e-213 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NIDDKIGC_00270 2.3e-295 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
NIDDKIGC_00271 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_00272 3.1e-201 bla2 3.5.2.6 V Beta-lactamase enzyme family
NIDDKIGC_00273 6.2e-82 usp6 T universal stress protein
NIDDKIGC_00274 1.5e-38
NIDDKIGC_00275 8e-238 rarA L recombination factor protein RarA
NIDDKIGC_00276 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIDDKIGC_00277 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
NIDDKIGC_00278 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
NIDDKIGC_00279 3.6e-103 G PTS system sorbose-specific iic component
NIDDKIGC_00280 2.7e-104 G PTS system mannose fructose sorbose family IID component
NIDDKIGC_00281 9.2e-42 2.7.1.191 G PTS system fructose IIA component
NIDDKIGC_00282 5.1e-232 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NIDDKIGC_00283 3.3e-43 czrA K Helix-turn-helix domain
NIDDKIGC_00284 9.1e-110 S Protein of unknown function (DUF1648)
NIDDKIGC_00285 3.3e-80 yueI S Protein of unknown function (DUF1694)
NIDDKIGC_00286 1.1e-112 yktB S Belongs to the UPF0637 family
NIDDKIGC_00287 9.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NIDDKIGC_00288 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
NIDDKIGC_00289 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NIDDKIGC_00290 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
NIDDKIGC_00291 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NIDDKIGC_00292 8e-235 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
NIDDKIGC_00293 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NIDDKIGC_00294 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NIDDKIGC_00295 4.7e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIDDKIGC_00296 3e-116 radC L DNA repair protein
NIDDKIGC_00297 2.8e-161 mreB D cell shape determining protein MreB
NIDDKIGC_00298 9.9e-144 mreC M Involved in formation and maintenance of cell shape
NIDDKIGC_00299 1.2e-88 mreD M rod shape-determining protein MreD
NIDDKIGC_00300 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NIDDKIGC_00301 1.2e-146 minD D Belongs to the ParA family
NIDDKIGC_00302 4.6e-109 glnP P ABC transporter permease
NIDDKIGC_00303 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIDDKIGC_00304 1.5e-155 aatB ET ABC transporter substrate-binding protein
NIDDKIGC_00305 0.0 L Transposase
NIDDKIGC_00306 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
NIDDKIGC_00307 6.5e-232 ymfF S Peptidase M16 inactive domain protein
NIDDKIGC_00308 2.1e-249 ymfH S Peptidase M16
NIDDKIGC_00309 5.7e-110 ymfM S Helix-turn-helix domain
NIDDKIGC_00310 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NIDDKIGC_00311 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
NIDDKIGC_00312 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NIDDKIGC_00313 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
NIDDKIGC_00314 2.7e-154 ymdB S YmdB-like protein
NIDDKIGC_00315 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NIDDKIGC_00316 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NIDDKIGC_00317 1.3e-72
NIDDKIGC_00318 0.0 S Bacterial membrane protein YfhO
NIDDKIGC_00319 8.7e-90
NIDDKIGC_00320 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NIDDKIGC_00321 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NIDDKIGC_00322 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NIDDKIGC_00323 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NIDDKIGC_00324 2.8e-29 yajC U Preprotein translocase
NIDDKIGC_00325 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NIDDKIGC_00326 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NIDDKIGC_00327 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NIDDKIGC_00328 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NIDDKIGC_00329 2.4e-43 yrzL S Belongs to the UPF0297 family
NIDDKIGC_00330 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NIDDKIGC_00331 1.6e-48 yrzB S Belongs to the UPF0473 family
NIDDKIGC_00332 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NIDDKIGC_00333 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NIDDKIGC_00334 3.3e-52 trxA O Belongs to the thioredoxin family
NIDDKIGC_00335 7.6e-126 yslB S Protein of unknown function (DUF2507)
NIDDKIGC_00336 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NIDDKIGC_00337 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NIDDKIGC_00338 9.5e-97 S Phosphoesterase
NIDDKIGC_00339 6.5e-87 ykuL S (CBS) domain
NIDDKIGC_00340 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NIDDKIGC_00341 3.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NIDDKIGC_00342 2.6e-158 ykuT M mechanosensitive ion channel
NIDDKIGC_00343 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NIDDKIGC_00344 2.8e-56
NIDDKIGC_00345 1.1e-80 K helix_turn_helix, mercury resistance
NIDDKIGC_00346 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIDDKIGC_00347 1.2e-180 ccpA K catabolite control protein A
NIDDKIGC_00348 5.8e-163 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
NIDDKIGC_00349 5.4e-50 S DsrE/DsrF-like family
NIDDKIGC_00350 8.3e-131 yebC K Transcriptional regulatory protein
NIDDKIGC_00351 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIDDKIGC_00352 5.6e-175 comGA NU Type II IV secretion system protein
NIDDKIGC_00353 9.6e-189 comGB NU type II secretion system
NIDDKIGC_00354 5.5e-43 comGC U competence protein ComGC
NIDDKIGC_00355 3.2e-83 gspG NU general secretion pathway protein
NIDDKIGC_00356 8.6e-20
NIDDKIGC_00357 4.5e-88 S Prokaryotic N-terminal methylation motif
NIDDKIGC_00359 1.2e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NIDDKIGC_00360 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIDDKIGC_00361 2.1e-252 cycA E Amino acid permease
NIDDKIGC_00362 4.4e-117 S Calcineurin-like phosphoesterase
NIDDKIGC_00363 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NIDDKIGC_00364 1.5e-80 yutD S Protein of unknown function (DUF1027)
NIDDKIGC_00365 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NIDDKIGC_00366 4.6e-117 S Protein of unknown function (DUF1461)
NIDDKIGC_00367 1.9e-118 dedA S SNARE-like domain protein
NIDDKIGC_00368 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NIDDKIGC_00369 1.6e-75 yugI 5.3.1.9 J general stress protein
NIDDKIGC_00370 5.1e-63
NIDDKIGC_00371 1.5e-42 S COG NOG38524 non supervised orthologous group
NIDDKIGC_00383 5.5e-08
NIDDKIGC_00393 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NIDDKIGC_00394 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
NIDDKIGC_00395 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NIDDKIGC_00396 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NIDDKIGC_00397 2.2e-204 coiA 3.6.4.12 S Competence protein
NIDDKIGC_00398 0.0 pepF E oligoendopeptidase F
NIDDKIGC_00399 3.6e-114 yjbH Q Thioredoxin
NIDDKIGC_00400 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
NIDDKIGC_00401 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NIDDKIGC_00402 4.4e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
NIDDKIGC_00403 5.1e-116 cutC P Participates in the control of copper homeostasis
NIDDKIGC_00404 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NIDDKIGC_00405 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NIDDKIGC_00406 4.3e-206 XK27_05220 S AI-2E family transporter
NIDDKIGC_00407 8.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NIDDKIGC_00408 3.1e-161 rrmA 2.1.1.187 H Methyltransferase
NIDDKIGC_00410 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
NIDDKIGC_00411 3.1e-113 ywnB S NAD(P)H-binding
NIDDKIGC_00412 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NIDDKIGC_00413 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NIDDKIGC_00414 4.2e-175 corA P CorA-like Mg2+ transporter protein
NIDDKIGC_00415 1.9e-62 S Protein of unknown function (DUF3397)
NIDDKIGC_00416 1.9e-77 mraZ K Belongs to the MraZ family
NIDDKIGC_00417 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NIDDKIGC_00418 7.5e-54 ftsL D Cell division protein FtsL
NIDDKIGC_00419 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NIDDKIGC_00420 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NIDDKIGC_00421 2.3e-259 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NIDDKIGC_00422 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NIDDKIGC_00423 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NIDDKIGC_00424 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NIDDKIGC_00425 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NIDDKIGC_00426 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NIDDKIGC_00427 1.2e-36 yggT S YGGT family
NIDDKIGC_00428 9.9e-146 ylmH S S4 domain protein
NIDDKIGC_00429 1.2e-86 divIVA D DivIVA domain protein
NIDDKIGC_00430 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NIDDKIGC_00431 8.2e-74 cylA V abc transporter atp-binding protein
NIDDKIGC_00432 1.2e-80 cylB U ABC-2 type transporter
NIDDKIGC_00433 2.9e-36 K LytTr DNA-binding domain
NIDDKIGC_00434 9e-18 S Protein of unknown function (DUF3021)
NIDDKIGC_00435 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NIDDKIGC_00436 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NIDDKIGC_00437 4.6e-28
NIDDKIGC_00438 1.1e-121 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NIDDKIGC_00439 7.1e-217 iscS 2.8.1.7 E Aminotransferase class V
NIDDKIGC_00440 4.9e-57 XK27_04120 S Putative amino acid metabolism
NIDDKIGC_00441 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NIDDKIGC_00442 1.3e-241 ktrB P Potassium uptake protein
NIDDKIGC_00443 2.6e-115 ktrA P domain protein
NIDDKIGC_00444 2.3e-120 N WxL domain surface cell wall-binding
NIDDKIGC_00445 1.7e-193 S Bacterial protein of unknown function (DUF916)
NIDDKIGC_00446 4.2e-267 N domain, Protein
NIDDKIGC_00447 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
NIDDKIGC_00448 1.6e-120 S Repeat protein
NIDDKIGC_00449 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NIDDKIGC_00450 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIDDKIGC_00451 4.1e-108 mltD CBM50 M NlpC P60 family protein
NIDDKIGC_00452 1.7e-28
NIDDKIGC_00453 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NIDDKIGC_00454 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIDDKIGC_00455 3.1e-33 ykzG S Belongs to the UPF0356 family
NIDDKIGC_00456 1.6e-85
NIDDKIGC_00457 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NIDDKIGC_00458 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
NIDDKIGC_00459 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
NIDDKIGC_00460 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NIDDKIGC_00461 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
NIDDKIGC_00462 6.8e-162 1.1.1.27 C L-malate dehydrogenase activity
NIDDKIGC_00463 3.3e-46 yktA S Belongs to the UPF0223 family
NIDDKIGC_00464 1.2e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
NIDDKIGC_00465 0.0 typA T GTP-binding protein TypA
NIDDKIGC_00466 4.1e-197
NIDDKIGC_00467 7.6e-29
NIDDKIGC_00468 1.3e-61
NIDDKIGC_00469 5.1e-259 ica2 GT2 M Glycosyl transferase family group 2
NIDDKIGC_00470 3.5e-240
NIDDKIGC_00471 1.6e-205 ftsW D Belongs to the SEDS family
NIDDKIGC_00472 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NIDDKIGC_00473 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NIDDKIGC_00474 1.1e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NIDDKIGC_00475 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NIDDKIGC_00476 1.6e-196 ylbL T Belongs to the peptidase S16 family
NIDDKIGC_00477 1.3e-120 comEA L Competence protein ComEA
NIDDKIGC_00478 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
NIDDKIGC_00479 0.0 comEC S Competence protein ComEC
NIDDKIGC_00480 1.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
NIDDKIGC_00481 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
NIDDKIGC_00482 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NIDDKIGC_00483 2.8e-192 mdtG EGP Major Facilitator Superfamily
NIDDKIGC_00484 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIDDKIGC_00485 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NIDDKIGC_00486 2.2e-157 S Tetratricopeptide repeat
NIDDKIGC_00487 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NIDDKIGC_00488 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NIDDKIGC_00489 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NIDDKIGC_00490 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
NIDDKIGC_00491 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
NIDDKIGC_00492 9.9e-73 S Iron-sulphur cluster biosynthesis
NIDDKIGC_00493 4.3e-22
NIDDKIGC_00494 9.2e-270 glnPH2 P ABC transporter permease
NIDDKIGC_00495 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIDDKIGC_00496 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NIDDKIGC_00497 9e-128 epsB M biosynthesis protein
NIDDKIGC_00498 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NIDDKIGC_00499 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
NIDDKIGC_00500 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
NIDDKIGC_00501 1.8e-127 tuaA M Bacterial sugar transferase
NIDDKIGC_00502 4.6e-194 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
NIDDKIGC_00503 1.2e-178 cps4G M Glycosyltransferase Family 4
NIDDKIGC_00504 2e-228
NIDDKIGC_00505 3.3e-175 cps4I M Glycosyltransferase like family 2
NIDDKIGC_00506 2.5e-259 cps4J S Polysaccharide biosynthesis protein
NIDDKIGC_00507 1e-251 cpdA S Calcineurin-like phosphoesterase
NIDDKIGC_00508 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
NIDDKIGC_00509 4.6e-171 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NIDDKIGC_00510 1.5e-135 fruR K DeoR C terminal sensor domain
NIDDKIGC_00511 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NIDDKIGC_00512 3.2e-46
NIDDKIGC_00513 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NIDDKIGC_00514 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_00515 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
NIDDKIGC_00516 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NIDDKIGC_00517 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NIDDKIGC_00518 1e-102 K Helix-turn-helix domain
NIDDKIGC_00519 1.6e-211 EGP Major facilitator Superfamily
NIDDKIGC_00520 8.5e-57 ybjQ S Belongs to the UPF0145 family
NIDDKIGC_00521 2.9e-142 Q Methyltransferase
NIDDKIGC_00522 1.6e-31
NIDDKIGC_00523 5.9e-62 L Belongs to the 'phage' integrase family
NIDDKIGC_00529 7.9e-11 tcdC
NIDDKIGC_00530 1.6e-83 K Peptidase S24-like
NIDDKIGC_00531 2.9e-11
NIDDKIGC_00532 2.9e-64 S DNA binding
NIDDKIGC_00535 5.6e-10
NIDDKIGC_00541 1.5e-55 L DnaD domain protein
NIDDKIGC_00542 1.9e-144 pi346 L IstB-like ATP binding protein
NIDDKIGC_00544 4.2e-44
NIDDKIGC_00547 2.8e-15
NIDDKIGC_00548 1.7e-95 2.1.1.37 L C-5 cytosine-specific DNA methylase
NIDDKIGC_00549 1.8e-65 S Transcriptional regulator, RinA family
NIDDKIGC_00551 9.2e-15
NIDDKIGC_00552 1.2e-88 L HNH nucleases
NIDDKIGC_00553 2e-45 L Phage terminase, small subunit
NIDDKIGC_00554 1.5e-179 S Phage Terminase
NIDDKIGC_00555 2.2e-22 S Protein of unknown function (DUF1056)
NIDDKIGC_00556 4.4e-206 S Phage portal protein
NIDDKIGC_00557 2.4e-125 S Clp protease
NIDDKIGC_00558 6.8e-210 S Phage capsid family
NIDDKIGC_00559 9.1e-56 S Phage gp6-like head-tail connector protein
NIDDKIGC_00560 6.8e-25 S Phage head-tail joining protein
NIDDKIGC_00561 2.7e-39
NIDDKIGC_00562 7.7e-27
NIDDKIGC_00563 3.2e-70 S Phage tail tube protein
NIDDKIGC_00566 0.0 S peptidoglycan catabolic process
NIDDKIGC_00567 0.0 S Phage tail protein
NIDDKIGC_00568 0.0 S Phage minor structural protein
NIDDKIGC_00569 3.4e-193
NIDDKIGC_00572 2.7e-51
NIDDKIGC_00573 4.5e-195 lys M Glycosyl hydrolases family 25
NIDDKIGC_00574 3.3e-37 S Haemolysin XhlA
NIDDKIGC_00577 4.5e-230 rodA D Cell cycle protein
NIDDKIGC_00578 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
NIDDKIGC_00579 7.9e-143 P ATPases associated with a variety of cellular activities
NIDDKIGC_00580 2.1e-221 lytR5 K Cell envelope-related transcriptional attenuator domain
NIDDKIGC_00581 9.2e-101 L Helix-turn-helix domain
NIDDKIGC_00582 3.4e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
NIDDKIGC_00583 1.3e-66
NIDDKIGC_00584 1.1e-76
NIDDKIGC_00585 3.9e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NIDDKIGC_00586 3.7e-87
NIDDKIGC_00587 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NIDDKIGC_00588 2.9e-36 ynzC S UPF0291 protein
NIDDKIGC_00589 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
NIDDKIGC_00590 6.4e-119 plsC 2.3.1.51 I Acyltransferase
NIDDKIGC_00591 2.8e-137 yabB 2.1.1.223 L Methyltransferase small domain
NIDDKIGC_00592 2e-49 yazA L GIY-YIG catalytic domain protein
NIDDKIGC_00593 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIDDKIGC_00594 4.7e-134 S Haloacid dehalogenase-like hydrolase
NIDDKIGC_00595 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
NIDDKIGC_00596 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NIDDKIGC_00597 5e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NIDDKIGC_00598 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NIDDKIGC_00599 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NIDDKIGC_00600 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
NIDDKIGC_00601 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NIDDKIGC_00602 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NIDDKIGC_00603 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIDDKIGC_00604 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
NIDDKIGC_00605 1.3e-216 nusA K Participates in both transcription termination and antitermination
NIDDKIGC_00606 9.5e-49 ylxR K Protein of unknown function (DUF448)
NIDDKIGC_00607 1.1e-47 ylxQ J ribosomal protein
NIDDKIGC_00608 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NIDDKIGC_00609 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NIDDKIGC_00610 6.7e-265 ydiN 5.4.99.5 G Major Facilitator
NIDDKIGC_00611 4.6e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NIDDKIGC_00612 3.8e-93
NIDDKIGC_00613 1.7e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NIDDKIGC_00614 7.2e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NIDDKIGC_00615 3.4e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NIDDKIGC_00616 1.6e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NIDDKIGC_00617 2.7e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NIDDKIGC_00618 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
NIDDKIGC_00619 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NIDDKIGC_00620 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NIDDKIGC_00621 0.0 dnaK O Heat shock 70 kDa protein
NIDDKIGC_00622 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NIDDKIGC_00623 1.3e-197 pbpX2 V Beta-lactamase
NIDDKIGC_00624 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
NIDDKIGC_00625 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIDDKIGC_00626 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
NIDDKIGC_00627 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIDDKIGC_00628 3e-245 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NIDDKIGC_00629 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIDDKIGC_00630 1.2e-48
NIDDKIGC_00631 1.4e-49
NIDDKIGC_00632 3.6e-114 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NIDDKIGC_00633 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
NIDDKIGC_00634 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NIDDKIGC_00635 9.6e-58
NIDDKIGC_00636 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NIDDKIGC_00637 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NIDDKIGC_00638 7.9e-114 3.1.3.18 J HAD-hyrolase-like
NIDDKIGC_00639 1.2e-165 yniA G Fructosamine kinase
NIDDKIGC_00640 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NIDDKIGC_00641 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
NIDDKIGC_00642 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NIDDKIGC_00643 9.4e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIDDKIGC_00644 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NIDDKIGC_00645 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIDDKIGC_00646 4.5e-171 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NIDDKIGC_00647 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
NIDDKIGC_00648 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NIDDKIGC_00649 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NIDDKIGC_00650 2.6e-71 yqeY S YqeY-like protein
NIDDKIGC_00651 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
NIDDKIGC_00652 6.6e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NIDDKIGC_00653 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NIDDKIGC_00654 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NIDDKIGC_00655 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
NIDDKIGC_00656 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NIDDKIGC_00657 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NIDDKIGC_00658 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NIDDKIGC_00659 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NIDDKIGC_00660 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
NIDDKIGC_00661 4.8e-165 ytrB V ABC transporter, ATP-binding protein
NIDDKIGC_00662 9.2e-203
NIDDKIGC_00663 1.1e-197
NIDDKIGC_00664 9.8e-127 S ABC-2 family transporter protein
NIDDKIGC_00665 3.9e-162 V ABC transporter, ATP-binding protein
NIDDKIGC_00666 2.6e-12 yjdF S Protein of unknown function (DUF2992)
NIDDKIGC_00667 1e-114 S Psort location CytoplasmicMembrane, score
NIDDKIGC_00668 1.6e-79 K MarR family
NIDDKIGC_00669 6e-82 K Acetyltransferase (GNAT) domain
NIDDKIGC_00671 5.2e-159 yvfR V ABC transporter
NIDDKIGC_00672 1.1e-133 yvfS V ABC-2 type transporter
NIDDKIGC_00673 2.2e-204 desK 2.7.13.3 T Histidine kinase
NIDDKIGC_00674 1.2e-103 desR K helix_turn_helix, Lux Regulon
NIDDKIGC_00675 3e-270 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NIDDKIGC_00676 2.8e-14 S Alpha beta hydrolase
NIDDKIGC_00677 8.7e-173 C nadph quinone reductase
NIDDKIGC_00678 3.6e-160 K Transcriptional regulator
NIDDKIGC_00679 2.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
NIDDKIGC_00680 9e-113 GM NmrA-like family
NIDDKIGC_00681 8.5e-159 S Alpha beta hydrolase
NIDDKIGC_00682 3.4e-129 K Helix-turn-helix domain, rpiR family
NIDDKIGC_00683 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NIDDKIGC_00684 1.4e-113 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
NIDDKIGC_00685 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_00686 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_00687 1.2e-14 K Bacterial regulatory proteins, tetR family
NIDDKIGC_00688 5.2e-213 S membrane
NIDDKIGC_00689 3.5e-81 K Bacterial regulatory proteins, tetR family
NIDDKIGC_00690 0.0 CP_1020 S Zinc finger, swim domain protein
NIDDKIGC_00691 1.2e-112 GM epimerase
NIDDKIGC_00692 1.4e-68 S Protein of unknown function (DUF1722)
NIDDKIGC_00693 9.1e-71 yneH 1.20.4.1 P ArsC family
NIDDKIGC_00694 9.1e-107 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
NIDDKIGC_00695 1e-136 K DeoR C terminal sensor domain
NIDDKIGC_00696 7.1e-116 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NIDDKIGC_00697 1.2e-183 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NIDDKIGC_00698 1.4e-212 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIDDKIGC_00699 4.3e-77 K Transcriptional regulator
NIDDKIGC_00700 1.3e-241 EGP Major facilitator Superfamily
NIDDKIGC_00701 1.1e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIDDKIGC_00702 1.7e-74 3.6.3.6 P Cation transporter/ATPase, N-terminus
NIDDKIGC_00703 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
NIDDKIGC_00704 9.3e-173 C Zinc-binding dehydrogenase
NIDDKIGC_00705 8.5e-220 I transferase activity, transferring acyl groups other than amino-acyl groups
NIDDKIGC_00706 7.8e-208
NIDDKIGC_00707 2.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_00708 7.8e-61 P Rhodanese Homology Domain
NIDDKIGC_00709 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NIDDKIGC_00710 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_00711 3.2e-167 drrA V ABC transporter
NIDDKIGC_00712 5.4e-120 drrB U ABC-2 type transporter
NIDDKIGC_00713 6.9e-223 M O-Antigen ligase
NIDDKIGC_00714 2.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
NIDDKIGC_00715 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NIDDKIGC_00716 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NIDDKIGC_00717 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIDDKIGC_00719 5.6e-29 S Protein of unknown function (DUF2929)
NIDDKIGC_00720 0.0 dnaE 2.7.7.7 L DNA polymerase
NIDDKIGC_00721 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NIDDKIGC_00722 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NIDDKIGC_00723 1.5e-74 yeaL S Protein of unknown function (DUF441)
NIDDKIGC_00724 2.9e-170 cvfB S S1 domain
NIDDKIGC_00725 1.1e-164 xerD D recombinase XerD
NIDDKIGC_00726 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NIDDKIGC_00727 8.2e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NIDDKIGC_00728 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NIDDKIGC_00729 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIDDKIGC_00730 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NIDDKIGC_00731 4.2e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
NIDDKIGC_00732 1.7e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
NIDDKIGC_00733 2e-19 M Lysin motif
NIDDKIGC_00734 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NIDDKIGC_00735 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
NIDDKIGC_00736 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NIDDKIGC_00737 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NIDDKIGC_00738 3.3e-215 S Tetratricopeptide repeat protein
NIDDKIGC_00739 2e-149 3.1.3.102, 3.1.3.104 S hydrolase
NIDDKIGC_00740 2.1e-143 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NIDDKIGC_00741 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NIDDKIGC_00742 9.6e-85
NIDDKIGC_00743 0.0 yfmR S ABC transporter, ATP-binding protein
NIDDKIGC_00744 1e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NIDDKIGC_00745 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NIDDKIGC_00746 5.1e-148 DegV S EDD domain protein, DegV family
NIDDKIGC_00747 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
NIDDKIGC_00748 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
NIDDKIGC_00749 3.4e-35 yozE S Belongs to the UPF0346 family
NIDDKIGC_00750 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NIDDKIGC_00751 3.3e-251 emrY EGP Major facilitator Superfamily
NIDDKIGC_00752 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
NIDDKIGC_00753 1.3e-125 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NIDDKIGC_00754 8.9e-170 cpsY K Transcriptional regulator, LysR family
NIDDKIGC_00755 1.4e-228 XK27_05470 E Methionine synthase
NIDDKIGC_00757 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NIDDKIGC_00758 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NIDDKIGC_00759 3.3e-158 dprA LU DNA protecting protein DprA
NIDDKIGC_00760 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NIDDKIGC_00761 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NIDDKIGC_00762 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
NIDDKIGC_00763 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NIDDKIGC_00764 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NIDDKIGC_00765 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
NIDDKIGC_00766 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NIDDKIGC_00767 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIDDKIGC_00768 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NIDDKIGC_00769 1.2e-177 K Transcriptional regulator
NIDDKIGC_00770 3.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
NIDDKIGC_00771 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NIDDKIGC_00772 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIDDKIGC_00773 4.2e-32 S YozE SAM-like fold
NIDDKIGC_00774 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
NIDDKIGC_00775 4.2e-278 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIDDKIGC_00776 1.4e-245 M Glycosyl transferase family group 2
NIDDKIGC_00777 8.7e-66
NIDDKIGC_00778 2.7e-252 gshR1 1.8.1.7 C Glutathione reductase
NIDDKIGC_00779 3.9e-75 mgrA K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_00780 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NIDDKIGC_00781 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIDDKIGC_00782 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIDDKIGC_00783 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
NIDDKIGC_00784 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
NIDDKIGC_00785 5.1e-227
NIDDKIGC_00786 6.8e-279 lldP C L-lactate permease
NIDDKIGC_00787 1.6e-58
NIDDKIGC_00788 5.6e-121
NIDDKIGC_00789 1e-243 cycA E Amino acid permease
NIDDKIGC_00790 1.2e-133 XK27_00890 S Domain of unknown function (DUF368)
NIDDKIGC_00791 1.5e-128 yejC S Protein of unknown function (DUF1003)
NIDDKIGC_00792 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
NIDDKIGC_00793 4.6e-12
NIDDKIGC_00794 3.3e-209 pmrB EGP Major facilitator Superfamily
NIDDKIGC_00795 1.4e-147 2.7.7.12 C Domain of unknown function (DUF4931)
NIDDKIGC_00796 1.6e-48
NIDDKIGC_00797 1.7e-09
NIDDKIGC_00798 3.4e-132 S Protein of unknown function (DUF975)
NIDDKIGC_00799 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
NIDDKIGC_00800 7e-161 degV S EDD domain protein, DegV family
NIDDKIGC_00801 1.9e-66 K Transcriptional regulator
NIDDKIGC_00802 0.0 FbpA K Fibronectin-binding protein
NIDDKIGC_00803 3.5e-132 S ABC-2 family transporter protein
NIDDKIGC_00804 2.4e-164 V ABC transporter, ATP-binding protein
NIDDKIGC_00805 3e-92 3.6.1.55 F NUDIX domain
NIDDKIGC_00807 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
NIDDKIGC_00808 3.5e-69 S LuxR family transcriptional regulator
NIDDKIGC_00809 1.4e-18 cat 2.3.1.28 V Chloramphenicol acetyltransferase
NIDDKIGC_00810 3.6e-87 cat 2.3.1.28 V Chloramphenicol acetyltransferase
NIDDKIGC_00813 5.8e-70 frataxin S Domain of unknown function (DU1801)
NIDDKIGC_00814 6.4e-113 pgm5 G Phosphoglycerate mutase family
NIDDKIGC_00815 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIDDKIGC_00816 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
NIDDKIGC_00817 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIDDKIGC_00818 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIDDKIGC_00819 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NIDDKIGC_00820 4.1e-295 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NIDDKIGC_00821 3.3e-62 esbA S Family of unknown function (DUF5322)
NIDDKIGC_00822 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
NIDDKIGC_00823 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
NIDDKIGC_00824 9.2e-104 S hydrolase activity, acting on ester bonds
NIDDKIGC_00825 5.5e-21 S hydrolase activity, acting on ester bonds
NIDDKIGC_00826 1.1e-192
NIDDKIGC_00827 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
NIDDKIGC_00828 7.3e-122
NIDDKIGC_00829 1.7e-73 XK27_05710 K Acetyltransferase (GNAT) domain
NIDDKIGC_00830 1.6e-182 mccF 3.4.17.13 V LD-carboxypeptidase
NIDDKIGC_00831 4.5e-239 M hydrolase, family 25
NIDDKIGC_00832 1.2e-46 K Acetyltransferase (GNAT) domain
NIDDKIGC_00833 1.2e-207 mccF V LD-carboxypeptidase
NIDDKIGC_00834 9.2e-200 M Glycosyltransferase, group 2 family protein
NIDDKIGC_00835 4.4e-73 S SnoaL-like domain
NIDDKIGC_00836 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NIDDKIGC_00837 6.8e-243 P Major Facilitator Superfamily
NIDDKIGC_00838 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_00839 4e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NIDDKIGC_00841 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NIDDKIGC_00842 8.3e-110 ypsA S Belongs to the UPF0398 family
NIDDKIGC_00843 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NIDDKIGC_00844 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NIDDKIGC_00845 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
NIDDKIGC_00846 9.3e-181 ftpB P Bacterial extracellular solute-binding protein
NIDDKIGC_00847 1.6e-302 ftpA P Binding-protein-dependent transport system inner membrane component
NIDDKIGC_00848 7.6e-83 uspA T Universal stress protein family
NIDDKIGC_00849 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
NIDDKIGC_00850 7.7e-99 metI P ABC transporter permease
NIDDKIGC_00851 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NIDDKIGC_00853 1.3e-128 dnaD L Replication initiation and membrane attachment
NIDDKIGC_00854 2.1e-257 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NIDDKIGC_00855 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NIDDKIGC_00856 2.1e-72 ypmB S protein conserved in bacteria
NIDDKIGC_00857 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NIDDKIGC_00858 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
NIDDKIGC_00859 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NIDDKIGC_00860 2.9e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NIDDKIGC_00861 3.6e-196 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NIDDKIGC_00862 2.5e-194 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NIDDKIGC_00863 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NIDDKIGC_00864 9.6e-250 malT G Major Facilitator
NIDDKIGC_00865 2.1e-88 S Domain of unknown function (DUF4767)
NIDDKIGC_00866 9.4e-269 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
NIDDKIGC_00867 1.2e-149 yitU 3.1.3.104 S hydrolase
NIDDKIGC_00868 1.4e-265 yfnA E Amino Acid
NIDDKIGC_00869 7.4e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NIDDKIGC_00870 4.2e-43
NIDDKIGC_00871 3.9e-50
NIDDKIGC_00872 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
NIDDKIGC_00873 1e-170 2.5.1.74 H UbiA prenyltransferase family
NIDDKIGC_00874 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NIDDKIGC_00875 5.1e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NIDDKIGC_00876 7.3e-280 pipD E Dipeptidase
NIDDKIGC_00877 9.4e-40
NIDDKIGC_00878 4.8e-29 S CsbD-like
NIDDKIGC_00879 6.5e-41 S transglycosylase associated protein
NIDDKIGC_00880 3.1e-14
NIDDKIGC_00881 3.5e-36
NIDDKIGC_00882 4.8e-17 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
NIDDKIGC_00883 2e-123 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
NIDDKIGC_00884 8e-66 S Protein of unknown function (DUF805)
NIDDKIGC_00885 1.4e-75 uspA T Belongs to the universal stress protein A family
NIDDKIGC_00886 4.3e-67 tspO T TspO/MBR family
NIDDKIGC_00887 7.9e-41
NIDDKIGC_00888 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
NIDDKIGC_00889 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
NIDDKIGC_00890 2.5e-209 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NIDDKIGC_00891 1.3e-28
NIDDKIGC_00892 8.5e-54
NIDDKIGC_00893 8.4e-14 K Bacterial regulatory proteins, tetR family
NIDDKIGC_00894 4.7e-85 S Protein of unknown function with HXXEE motif
NIDDKIGC_00895 1.2e-139 f42a O Band 7 protein
NIDDKIGC_00896 5.2e-301 norB EGP Major Facilitator
NIDDKIGC_00897 6.2e-94 K transcriptional regulator
NIDDKIGC_00898 1.5e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIDDKIGC_00899 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
NIDDKIGC_00900 2e-158 K LysR substrate binding domain
NIDDKIGC_00901 3.7e-123 S Protein of unknown function (DUF554)
NIDDKIGC_00902 2.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NIDDKIGC_00903 2.9e-134 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NIDDKIGC_00904 8.8e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NIDDKIGC_00905 3e-156 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIDDKIGC_00906 2.1e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NIDDKIGC_00907 1.2e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NIDDKIGC_00908 5.9e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIDDKIGC_00909 9.5e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NIDDKIGC_00910 1.2e-126 IQ reductase
NIDDKIGC_00911 3.1e-170 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NIDDKIGC_00912 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIDDKIGC_00913 2.6e-180 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIDDKIGC_00914 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NIDDKIGC_00915 1.5e-178 yneE K Transcriptional regulator
NIDDKIGC_00916 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_00917 8.5e-60 S Protein of unknown function (DUF1648)
NIDDKIGC_00918 1.2e-199 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NIDDKIGC_00919 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
NIDDKIGC_00920 2.4e-218 E glutamate:sodium symporter activity
NIDDKIGC_00921 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
NIDDKIGC_00922 2.6e-177 1.6.5.5 C Zinc-binding dehydrogenase
NIDDKIGC_00923 2e-97 entB 3.5.1.19 Q Isochorismatase family
NIDDKIGC_00924 1.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NIDDKIGC_00925 6.6e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NIDDKIGC_00926 5.5e-107 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NIDDKIGC_00927 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NIDDKIGC_00928 2.7e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NIDDKIGC_00929 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
NIDDKIGC_00930 1.7e-268 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
NIDDKIGC_00932 1.8e-271 XK27_00765
NIDDKIGC_00933 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
NIDDKIGC_00934 5.3e-86
NIDDKIGC_00935 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
NIDDKIGC_00936 6.8e-53
NIDDKIGC_00937 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NIDDKIGC_00938 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NIDDKIGC_00939 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NIDDKIGC_00940 2.6e-39 ylqC S Belongs to the UPF0109 family
NIDDKIGC_00941 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NIDDKIGC_00942 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NIDDKIGC_00943 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NIDDKIGC_00944 5.6e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NIDDKIGC_00945 0.0 smc D Required for chromosome condensation and partitioning
NIDDKIGC_00946 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NIDDKIGC_00947 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NIDDKIGC_00948 5.1e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NIDDKIGC_00949 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NIDDKIGC_00950 0.0 yloV S DAK2 domain fusion protein YloV
NIDDKIGC_00951 1.8e-57 asp S Asp23 family, cell envelope-related function
NIDDKIGC_00952 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NIDDKIGC_00953 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
NIDDKIGC_00954 3.3e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NIDDKIGC_00955 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NIDDKIGC_00956 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NIDDKIGC_00957 1.7e-134 stp 3.1.3.16 T phosphatase
NIDDKIGC_00958 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NIDDKIGC_00959 4.2e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NIDDKIGC_00960 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NIDDKIGC_00961 3.4e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NIDDKIGC_00962 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NIDDKIGC_00963 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NIDDKIGC_00964 3.6e-55
NIDDKIGC_00965 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
NIDDKIGC_00966 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIDDKIGC_00967 1.2e-104 opuCB E ABC transporter permease
NIDDKIGC_00968 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
NIDDKIGC_00969 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
NIDDKIGC_00970 7.4e-77 argR K Regulates arginine biosynthesis genes
NIDDKIGC_00971 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NIDDKIGC_00972 1.5e-158 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIDDKIGC_00973 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIDDKIGC_00974 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NIDDKIGC_00975 8.5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NIDDKIGC_00976 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NIDDKIGC_00977 3.5e-74 yqhY S Asp23 family, cell envelope-related function
NIDDKIGC_00978 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NIDDKIGC_00979 2.1e-191 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NIDDKIGC_00980 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NIDDKIGC_00981 3.2e-53 ysxB J Cysteine protease Prp
NIDDKIGC_00982 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NIDDKIGC_00983 1.8e-89 K Transcriptional regulator
NIDDKIGC_00984 5.4e-19
NIDDKIGC_00988 1.7e-30
NIDDKIGC_00989 5.3e-56
NIDDKIGC_00990 6.2e-99 dut S Protein conserved in bacteria
NIDDKIGC_00991 4e-181
NIDDKIGC_00992 2.5e-161
NIDDKIGC_00993 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
NIDDKIGC_00994 4.6e-64 glnR K Transcriptional regulator
NIDDKIGC_00995 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NIDDKIGC_00996 1.7e-139 glpQ 3.1.4.46 C phosphodiesterase
NIDDKIGC_00997 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
NIDDKIGC_00998 4.4e-68 yqhL P Rhodanese-like protein
NIDDKIGC_00999 2.1e-109 pepE 3.4.13.21 E Belongs to the peptidase S51 family
NIDDKIGC_01000 5.7e-180 glk 2.7.1.2 G Glucokinase
NIDDKIGC_01001 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
NIDDKIGC_01002 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
NIDDKIGC_01003 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NIDDKIGC_01004 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIDDKIGC_01005 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NIDDKIGC_01006 0.0 S membrane
NIDDKIGC_01007 3.8e-53 yneR S Belongs to the HesB IscA family
NIDDKIGC_01008 3.4e-74 XK27_02470 K LytTr DNA-binding domain
NIDDKIGC_01009 7.3e-95 liaI S membrane
NIDDKIGC_01010 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIDDKIGC_01011 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
NIDDKIGC_01012 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NIDDKIGC_01013 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIDDKIGC_01014 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NIDDKIGC_01015 7.4e-64 yodB K Transcriptional regulator, HxlR family
NIDDKIGC_01016 3.7e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIDDKIGC_01017 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIDDKIGC_01018 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NIDDKIGC_01019 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIDDKIGC_01020 8.4e-94 S SdpI/YhfL protein family
NIDDKIGC_01021 4.5e-227 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NIDDKIGC_01022 0.0 sbcC L Putative exonuclease SbcCD, C subunit
NIDDKIGC_01023 3.8e-171 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NIDDKIGC_01024 6.3e-304 arlS 2.7.13.3 T Histidine kinase
NIDDKIGC_01025 4.3e-121 K response regulator
NIDDKIGC_01026 5.5e-245 rarA L recombination factor protein RarA
NIDDKIGC_01027 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NIDDKIGC_01028 6.4e-171 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIDDKIGC_01029 6.7e-40 S Peptidase propeptide and YPEB domain
NIDDKIGC_01030 1e-34 S Peptidase propeptide and YPEB domain
NIDDKIGC_01031 1.6e-97 yceD S Uncharacterized ACR, COG1399
NIDDKIGC_01032 3.3e-214 ylbM S Belongs to the UPF0348 family
NIDDKIGC_01033 1.7e-139 yqeM Q Methyltransferase
NIDDKIGC_01034 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NIDDKIGC_01035 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NIDDKIGC_01036 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NIDDKIGC_01037 1.1e-50 yhbY J RNA-binding protein
NIDDKIGC_01038 2.2e-179 yqeH S Ribosome biogenesis GTPase YqeH
NIDDKIGC_01039 4e-98 yqeG S HAD phosphatase, family IIIA
NIDDKIGC_01040 1.3e-79
NIDDKIGC_01041 8.8e-248 pgaC GT2 M Glycosyl transferase
NIDDKIGC_01042 1.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
NIDDKIGC_01043 2.3e-62 hxlR K Transcriptional regulator, HxlR family
NIDDKIGC_01044 7.2e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
NIDDKIGC_01045 2.5e-239 yrvN L AAA C-terminal domain
NIDDKIGC_01046 1.1e-55
NIDDKIGC_01047 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NIDDKIGC_01048 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NIDDKIGC_01049 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NIDDKIGC_01050 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NIDDKIGC_01051 3.3e-172 dnaI L Primosomal protein DnaI
NIDDKIGC_01052 1.8e-246 dnaB L replication initiation and membrane attachment
NIDDKIGC_01053 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NIDDKIGC_01054 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NIDDKIGC_01055 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NIDDKIGC_01056 3.1e-30 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIDDKIGC_01057 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NIDDKIGC_01058 4.5e-121 ybhL S Belongs to the BI1 family
NIDDKIGC_01059 8.9e-111 hipB K Helix-turn-helix
NIDDKIGC_01060 5.5e-45 yitW S Iron-sulfur cluster assembly protein
NIDDKIGC_01061 7.2e-272 sufB O assembly protein SufB
NIDDKIGC_01062 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
NIDDKIGC_01063 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NIDDKIGC_01064 1.3e-243 sufD O FeS assembly protein SufD
NIDDKIGC_01065 4.2e-144 sufC O FeS assembly ATPase SufC
NIDDKIGC_01066 1.3e-34 feoA P FeoA domain
NIDDKIGC_01067 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
NIDDKIGC_01068 7.9e-21 S Virus attachment protein p12 family
NIDDKIGC_01069 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NIDDKIGC_01070 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NIDDKIGC_01071 5.3e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NIDDKIGC_01072 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
NIDDKIGC_01073 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NIDDKIGC_01074 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
NIDDKIGC_01075 4.8e-224 ecsB U ABC transporter
NIDDKIGC_01076 1.6e-134 ecsA V ABC transporter, ATP-binding protein
NIDDKIGC_01077 9.9e-82 hit FG histidine triad
NIDDKIGC_01078 3.5e-39
NIDDKIGC_01079 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIDDKIGC_01080 3.5e-78 S WxL domain surface cell wall-binding
NIDDKIGC_01081 4e-103 S WxL domain surface cell wall-binding
NIDDKIGC_01082 1.4e-192 S Fn3-like domain
NIDDKIGC_01083 7.9e-61
NIDDKIGC_01084 0.0
NIDDKIGC_01085 3.6e-241 npr 1.11.1.1 C NADH oxidase
NIDDKIGC_01086 3.3e-112 K Bacterial regulatory proteins, tetR family
NIDDKIGC_01087 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NIDDKIGC_01088 1.4e-106
NIDDKIGC_01089 9.3e-106 GBS0088 S Nucleotidyltransferase
NIDDKIGC_01090 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NIDDKIGC_01091 3.1e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NIDDKIGC_01092 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NIDDKIGC_01093 1.1e-171 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NIDDKIGC_01094 0.0 S membrane
NIDDKIGC_01095 3.9e-69 S NUDIX domain
NIDDKIGC_01096 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NIDDKIGC_01097 1.8e-184 ykoT GT2 M Glycosyl transferase family 2
NIDDKIGC_01098 1.3e-79 dedA S SNARE-like domain protein
NIDDKIGC_01099 2.6e-132 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NIDDKIGC_01100 2.2e-61 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatase
NIDDKIGC_01101 4.8e-104 K Transcriptional regulatory protein, C terminal
NIDDKIGC_01102 1.9e-160 T PhoQ Sensor
NIDDKIGC_01103 6e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NIDDKIGC_01104 4.2e-98
NIDDKIGC_01105 0.0 1.3.5.4 C FAD binding domain
NIDDKIGC_01106 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
NIDDKIGC_01107 1.2e-177 K LysR substrate binding domain
NIDDKIGC_01108 5.2e-181 3.4.21.102 M Peptidase family S41
NIDDKIGC_01109 8.7e-215
NIDDKIGC_01110 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIDDKIGC_01111 0.0 L AAA domain
NIDDKIGC_01112 5.7e-233 yhaO L Ser Thr phosphatase family protein
NIDDKIGC_01113 1e-54 yheA S Belongs to the UPF0342 family
NIDDKIGC_01114 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NIDDKIGC_01115 2.9e-12
NIDDKIGC_01116 4.4e-77 argR K Regulates arginine biosynthesis genes
NIDDKIGC_01117 3.2e-214 arcT 2.6.1.1 E Aminotransferase
NIDDKIGC_01118 5.2e-102 argO S LysE type translocator
NIDDKIGC_01119 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
NIDDKIGC_01120 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NIDDKIGC_01121 2e-114 M ErfK YbiS YcfS YnhG
NIDDKIGC_01122 1.2e-198 EGP Major facilitator Superfamily
NIDDKIGC_01123 1.5e-288 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_01124 1.6e-244 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01125 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_01126 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NIDDKIGC_01127 5.9e-61 S Domain of unknown function (DUF3284)
NIDDKIGC_01128 0.0 K PRD domain
NIDDKIGC_01129 7.6e-107
NIDDKIGC_01130 0.0 yhcA V MacB-like periplasmic core domain
NIDDKIGC_01131 1.4e-81
NIDDKIGC_01132 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NIDDKIGC_01133 7.7e-79 elaA S Acetyltransferase (GNAT) domain
NIDDKIGC_01136 1.9e-31
NIDDKIGC_01137 2.1e-244 dinF V MatE
NIDDKIGC_01138 0.0 yfbS P Sodium:sulfate symporter transmembrane region
NIDDKIGC_01139 3.9e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
NIDDKIGC_01140 1.5e-175 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
NIDDKIGC_01141 2.5e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
NIDDKIGC_01142 1.3e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
NIDDKIGC_01143 6.1e-307 S Protein conserved in bacteria
NIDDKIGC_01144 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NIDDKIGC_01145 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NIDDKIGC_01146 3.6e-58 S Protein of unknown function (DUF1516)
NIDDKIGC_01147 1.9e-89 gtcA S Teichoic acid glycosylation protein
NIDDKIGC_01148 2.1e-180
NIDDKIGC_01149 3.5e-10
NIDDKIGC_01150 1.1e-53
NIDDKIGC_01153 0.0 uvrA2 L ABC transporter
NIDDKIGC_01154 2.5e-46
NIDDKIGC_01155 1e-90
NIDDKIGC_01156 5.9e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_01157 5.1e-114 S CAAX protease self-immunity
NIDDKIGC_01158 2.5e-59
NIDDKIGC_01159 4.5e-55
NIDDKIGC_01160 1.6e-137 pltR K LytTr DNA-binding domain
NIDDKIGC_01161 8.2e-216 pltK 2.7.13.3 T GHKL domain
NIDDKIGC_01162 1.7e-108
NIDDKIGC_01163 6.5e-148 S Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_01164 1e-157 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NIDDKIGC_01165 5.1e-116 GM NAD(P)H-binding
NIDDKIGC_01166 3.6e-64 K helix_turn_helix, mercury resistance
NIDDKIGC_01167 7.7e-154 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NIDDKIGC_01169 5.7e-175 K LytTr DNA-binding domain
NIDDKIGC_01170 1.5e-155 V ABC transporter
NIDDKIGC_01171 8.2e-126 V Transport permease protein
NIDDKIGC_01173 4.6e-180 XK27_06930 V domain protein
NIDDKIGC_01174 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NIDDKIGC_01175 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
NIDDKIGC_01176 9.9e-126 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NIDDKIGC_01177 4.2e-261 ugpB G Bacterial extracellular solute-binding protein
NIDDKIGC_01178 1.1e-150 ugpE G ABC transporter permease
NIDDKIGC_01179 6.8e-173 ugpA U Binding-protein-dependent transport system inner membrane component
NIDDKIGC_01180 6.1e-202 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
NIDDKIGC_01181 4.1e-84 uspA T Belongs to the universal stress protein A family
NIDDKIGC_01182 1.1e-272 pepV 3.5.1.18 E dipeptidase PepV
NIDDKIGC_01183 1.7e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NIDDKIGC_01184 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NIDDKIGC_01185 3e-301 ytgP S Polysaccharide biosynthesis protein
NIDDKIGC_01186 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIDDKIGC_01187 1e-124 3.6.1.27 I Acid phosphatase homologues
NIDDKIGC_01188 2e-106 ytqB 2.1.1.176 J Putative rRNA methylase
NIDDKIGC_01189 4.2e-29
NIDDKIGC_01190 7.5e-299 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
NIDDKIGC_01191 5.1e-268 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
NIDDKIGC_01192 0.0 S Pfam Methyltransferase
NIDDKIGC_01193 1.4e-278 bmr3 EGP Major facilitator Superfamily
NIDDKIGC_01194 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NIDDKIGC_01195 3.1e-122
NIDDKIGC_01196 0.0 L Transposase
NIDDKIGC_01197 9.3e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
NIDDKIGC_01198 4.9e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NIDDKIGC_01199 1.2e-255 mmuP E amino acid
NIDDKIGC_01200 9e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NIDDKIGC_01201 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
NIDDKIGC_01203 3.9e-156 T Calcineurin-like phosphoesterase superfamily domain
NIDDKIGC_01204 2e-94 K Acetyltransferase (GNAT) domain
NIDDKIGC_01205 1.4e-95
NIDDKIGC_01206 6.8e-182 P secondary active sulfate transmembrane transporter activity
NIDDKIGC_01207 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
NIDDKIGC_01213 5.1e-08
NIDDKIGC_01219 1.5e-42 S COG NOG38524 non supervised orthologous group
NIDDKIGC_01222 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NIDDKIGC_01223 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
NIDDKIGC_01224 7.7e-227 patA 2.6.1.1 E Aminotransferase
NIDDKIGC_01225 4.3e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIDDKIGC_01226 1.7e-188 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIDDKIGC_01227 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
NIDDKIGC_01228 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
NIDDKIGC_01229 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NIDDKIGC_01230 2.7e-39 ptsH G phosphocarrier protein HPR
NIDDKIGC_01231 6.5e-30
NIDDKIGC_01232 0.0 clpE O Belongs to the ClpA ClpB family
NIDDKIGC_01233 1.6e-102 L Integrase
NIDDKIGC_01234 1e-63 K Winged helix DNA-binding domain
NIDDKIGC_01235 1.8e-181 oppF P Belongs to the ABC transporter superfamily
NIDDKIGC_01236 9.2e-203 oppD P Belongs to the ABC transporter superfamily
NIDDKIGC_01237 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIDDKIGC_01238 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NIDDKIGC_01239 1.5e-308 oppA E ABC transporter, substratebinding protein
NIDDKIGC_01240 3.2e-57 ywjH S Protein of unknown function (DUF1634)
NIDDKIGC_01241 5.5e-126 yxaA S membrane transporter protein
NIDDKIGC_01242 7.1e-161 lysR5 K LysR substrate binding domain
NIDDKIGC_01243 4.2e-197 M MucBP domain
NIDDKIGC_01244 5.9e-274
NIDDKIGC_01245 2e-307 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NIDDKIGC_01246 8.3e-254 gor 1.8.1.7 C Glutathione reductase
NIDDKIGC_01247 4.3e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
NIDDKIGC_01248 7.9e-293 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NIDDKIGC_01249 9.5e-213 gntP EG Gluconate
NIDDKIGC_01250 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NIDDKIGC_01251 9.3e-188 yueF S AI-2E family transporter
NIDDKIGC_01252 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIDDKIGC_01253 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
NIDDKIGC_01254 1e-47 K sequence-specific DNA binding
NIDDKIGC_01255 1.3e-134 cwlO M NlpC/P60 family
NIDDKIGC_01256 4.1e-106 ygaC J Belongs to the UPF0374 family
NIDDKIGC_01257 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
NIDDKIGC_01258 3.9e-125
NIDDKIGC_01259 1.5e-100 K DNA-templated transcription, initiation
NIDDKIGC_01260 1.3e-25
NIDDKIGC_01261 7e-30
NIDDKIGC_01262 7.3e-33 S Protein of unknown function (DUF2922)
NIDDKIGC_01263 1.1e-52
NIDDKIGC_01264 3.2e-121 rfbP M Bacterial sugar transferase
NIDDKIGC_01265 7e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
NIDDKIGC_01266 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_01267 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
NIDDKIGC_01268 6.7e-136 K helix_turn_helix, arabinose operon control protein
NIDDKIGC_01269 8.8e-147 cps1D M Domain of unknown function (DUF4422)
NIDDKIGC_01270 4.9e-204 cps3I G Acyltransferase family
NIDDKIGC_01271 1.3e-207 cps3H
NIDDKIGC_01272 2.7e-163 cps3F
NIDDKIGC_01273 4.8e-111 cps3E
NIDDKIGC_01274 2.2e-204 cps3D
NIDDKIGC_01275 1.1e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
NIDDKIGC_01276 8e-179 cps3B S Glycosyltransferase like family 2
NIDDKIGC_01277 6.5e-133 cps3A S Glycosyltransferase like family 2
NIDDKIGC_01278 7.9e-17 relB L bacterial-type proximal promoter sequence-specific DNA binding
NIDDKIGC_01279 6e-192 cps2I S Psort location CytoplasmicMembrane, score
NIDDKIGC_01280 3.4e-83 GT2 S Glycosyl transferase family 2
NIDDKIGC_01281 3.4e-19 S EpsG family
NIDDKIGC_01282 1.7e-89 V Glycosyl transferase, family 2
NIDDKIGC_01283 2e-140 M Teichoic acid biosynthesis protein
NIDDKIGC_01284 4e-37 M Pfam:DUF1792
NIDDKIGC_01285 2.7e-45 lsgF M Glycosyl transferase family 2
NIDDKIGC_01286 3.5e-123 tuaA M Bacterial sugar transferase
NIDDKIGC_01287 5.9e-177 cps2D 5.1.3.2 M RmlD substrate binding domain
NIDDKIGC_01288 3.8e-142 ywqE 3.1.3.48 GM PHP domain protein
NIDDKIGC_01289 2.4e-130 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NIDDKIGC_01290 1.6e-127 epsB M biosynthesis protein
NIDDKIGC_01291 6.2e-100 L Integrase
NIDDKIGC_01292 9.7e-153 cps2I S Psort location CytoplasmicMembrane, score
NIDDKIGC_01293 2.5e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NIDDKIGC_01294 1.9e-205 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NIDDKIGC_01295 4.6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
NIDDKIGC_01296 1.2e-147 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NIDDKIGC_01297 2.2e-43 3.2.1.1 GH13 G PFAM glycoside hydrolase family 39
NIDDKIGC_01299 1.3e-57
NIDDKIGC_01300 1.2e-58 G Glycosyltransferase Family 4
NIDDKIGC_01301 2.6e-134 rgpAc GT4 M Domain of unknown function (DUF1972)
NIDDKIGC_01302 1.5e-36 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NIDDKIGC_01303 1e-53 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIDDKIGC_01304 3.8e-38 GT2 V Glycosyl transferase, family 2
NIDDKIGC_01305 3.3e-57 pbpX2 V Beta-lactamase
NIDDKIGC_01307 2.5e-26 ps115 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_01308 7.6e-33 E Zn peptidase
NIDDKIGC_01309 0.0 L Transposase
NIDDKIGC_01310 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_01311 3.3e-156 yihY S Belongs to the UPF0761 family
NIDDKIGC_01312 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NIDDKIGC_01313 7.7e-219 pbpX1 V Beta-lactamase
NIDDKIGC_01314 3.4e-255 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
NIDDKIGC_01315 5e-107
NIDDKIGC_01316 1.3e-73
NIDDKIGC_01318 8.9e-164 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_01319 1.4e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01320 2.3e-75 T Universal stress protein family
NIDDKIGC_01322 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
NIDDKIGC_01323 2.4e-189 mocA S Oxidoreductase
NIDDKIGC_01324 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
NIDDKIGC_01325 1.1e-62 S Domain of unknown function (DUF4828)
NIDDKIGC_01326 2.4e-144 lys M Glycosyl hydrolases family 25
NIDDKIGC_01327 2.3e-151 gntR K rpiR family
NIDDKIGC_01328 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_01329 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01330 0.0 yfgQ P E1-E2 ATPase
NIDDKIGC_01331 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
NIDDKIGC_01332 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIDDKIGC_01333 1e-190 yegS 2.7.1.107 G Lipid kinase
NIDDKIGC_01334 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIDDKIGC_01335 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NIDDKIGC_01336 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NIDDKIGC_01337 4.8e-197 camS S sex pheromone
NIDDKIGC_01338 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NIDDKIGC_01339 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NIDDKIGC_01340 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NIDDKIGC_01341 1e-93 S UPF0316 protein
NIDDKIGC_01342 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NIDDKIGC_01343 3.1e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
NIDDKIGC_01344 8.7e-184 S Oxidoreductase family, NAD-binding Rossmann fold
NIDDKIGC_01345 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NIDDKIGC_01346 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIDDKIGC_01347 7.7e-156 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
NIDDKIGC_01348 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NIDDKIGC_01349 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NIDDKIGC_01350 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NIDDKIGC_01351 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
NIDDKIGC_01352 0.0 S Alpha beta
NIDDKIGC_01353 2.2e-24
NIDDKIGC_01354 3e-99 S ECF transporter, substrate-specific component
NIDDKIGC_01355 5.8e-253 yfnA E Amino Acid
NIDDKIGC_01356 1.4e-165 mleP S Sodium Bile acid symporter family
NIDDKIGC_01357 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
NIDDKIGC_01358 1.8e-167 mleR K LysR family
NIDDKIGC_01359 1.6e-160 mleR K LysR family transcriptional regulator
NIDDKIGC_01360 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NIDDKIGC_01361 2.7e-263 frdC 1.3.5.4 C FAD binding domain
NIDDKIGC_01362 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NIDDKIGC_01364 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NIDDKIGC_01365 5.5e-164 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NIDDKIGC_01366 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
NIDDKIGC_01367 4.8e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NIDDKIGC_01368 1.7e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
NIDDKIGC_01369 2.9e-179 citR K sugar-binding domain protein
NIDDKIGC_01370 2.2e-260 citP P Sodium:sulfate symporter transmembrane region
NIDDKIGC_01371 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIDDKIGC_01372 3.1e-50
NIDDKIGC_01373 4.6e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
NIDDKIGC_01374 4.8e-141 mtsB U ABC 3 transport family
NIDDKIGC_01375 4.5e-132 mntB 3.6.3.35 P ABC transporter
NIDDKIGC_01376 2.4e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NIDDKIGC_01377 1.7e-198 K Helix-turn-helix domain
NIDDKIGC_01378 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
NIDDKIGC_01379 5.4e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
NIDDKIGC_01380 4.1e-53 yitW S Iron-sulfur cluster assembly protein
NIDDKIGC_01381 4.7e-263 P Sodium:sulfate symporter transmembrane region
NIDDKIGC_01382 4.9e-196 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NIDDKIGC_01383 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
NIDDKIGC_01384 8.3e-165 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIDDKIGC_01385 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIDDKIGC_01386 4.2e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NIDDKIGC_01387 1.7e-183 ywhK S Membrane
NIDDKIGC_01388 4e-164 degV S Uncharacterised protein, DegV family COG1307
NIDDKIGC_01389 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
NIDDKIGC_01390 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NIDDKIGC_01391 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NIDDKIGC_01392 4.7e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIDDKIGC_01393 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIDDKIGC_01394 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NIDDKIGC_01395 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIDDKIGC_01396 3.5e-142 cad S FMN_bind
NIDDKIGC_01397 0.0 ndh 1.6.99.3 C NADH dehydrogenase
NIDDKIGC_01398 1.4e-86 ynhH S NusG domain II
NIDDKIGC_01399 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
NIDDKIGC_01400 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NIDDKIGC_01401 2.1e-61 rplQ J Ribosomal protein L17
NIDDKIGC_01402 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIDDKIGC_01403 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NIDDKIGC_01404 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NIDDKIGC_01405 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NIDDKIGC_01406 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NIDDKIGC_01407 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NIDDKIGC_01408 6.3e-70 rplO J Binds to the 23S rRNA
NIDDKIGC_01409 2.2e-24 rpmD J Ribosomal protein L30
NIDDKIGC_01410 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NIDDKIGC_01411 5.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NIDDKIGC_01412 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NIDDKIGC_01413 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NIDDKIGC_01414 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NIDDKIGC_01415 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NIDDKIGC_01416 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NIDDKIGC_01417 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NIDDKIGC_01418 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
NIDDKIGC_01419 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NIDDKIGC_01420 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NIDDKIGC_01421 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NIDDKIGC_01422 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NIDDKIGC_01423 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NIDDKIGC_01424 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NIDDKIGC_01425 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
NIDDKIGC_01426 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NIDDKIGC_01427 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NIDDKIGC_01428 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NIDDKIGC_01429 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NIDDKIGC_01430 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NIDDKIGC_01431 7.8e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NIDDKIGC_01432 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIDDKIGC_01433 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NIDDKIGC_01434 1.5e-109 K Bacterial regulatory proteins, tetR family
NIDDKIGC_01435 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NIDDKIGC_01436 6.9e-78 ctsR K Belongs to the CtsR family
NIDDKIGC_01444 0.0 L Transposase
NIDDKIGC_01445 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIDDKIGC_01446 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NIDDKIGC_01447 1.6e-113 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NIDDKIGC_01448 1.5e-264 lysP E amino acid
NIDDKIGC_01449 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NIDDKIGC_01450 4.2e-92 K Transcriptional regulator
NIDDKIGC_01451 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
NIDDKIGC_01452 2e-154 I alpha/beta hydrolase fold
NIDDKIGC_01453 2.3e-119 lssY 3.6.1.27 I phosphatase
NIDDKIGC_01454 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIDDKIGC_01455 2.2e-76 S Threonine/Serine exporter, ThrE
NIDDKIGC_01456 1.5e-130 thrE S Putative threonine/serine exporter
NIDDKIGC_01457 6e-31 cspC K Cold shock protein
NIDDKIGC_01458 2e-120 sirR K iron dependent repressor
NIDDKIGC_01459 2.6e-58
NIDDKIGC_01460 1.7e-84 merR K MerR HTH family regulatory protein
NIDDKIGC_01461 1.3e-171 lmrB EGP Major facilitator Superfamily
NIDDKIGC_01462 2.1e-88 lmrB EGP Major facilitator Superfamily
NIDDKIGC_01463 1.4e-117 S Domain of unknown function (DUF4811)
NIDDKIGC_01464 1.2e-62
NIDDKIGC_01465 4.4e-35 yyaN K MerR HTH family regulatory protein
NIDDKIGC_01466 2.2e-120 azlC E branched-chain amino acid
NIDDKIGC_01467 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
NIDDKIGC_01468 0.0 asnB 6.3.5.4 E Asparagine synthase
NIDDKIGC_01469 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
NIDDKIGC_01470 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NIDDKIGC_01471 1e-254 xylP2 G symporter
NIDDKIGC_01472 2e-191 nlhH_1 I alpha/beta hydrolase fold
NIDDKIGC_01473 4.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NIDDKIGC_01474 2.4e-101 3.2.2.20 K FR47-like protein
NIDDKIGC_01475 1.3e-126 yibF S overlaps another CDS with the same product name
NIDDKIGC_01476 3.7e-219 yibE S overlaps another CDS with the same product name
NIDDKIGC_01477 2.3e-179
NIDDKIGC_01478 5.6e-138 S NADPH-dependent FMN reductase
NIDDKIGC_01479 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_01480 1.4e-161 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
NIDDKIGC_01481 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NIDDKIGC_01482 4.1e-32 L leucine-zipper of insertion element IS481
NIDDKIGC_01483 1e-41
NIDDKIGC_01484 8.6e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NIDDKIGC_01485 6.7e-278 pipD E Dipeptidase
NIDDKIGC_01486 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
NIDDKIGC_01487 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NIDDKIGC_01488 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIDDKIGC_01489 8.8e-81 rmaD K Transcriptional regulator
NIDDKIGC_01491 0.0 1.3.5.4 C FMN_bind
NIDDKIGC_01492 6.1e-171 K Transcriptional regulator
NIDDKIGC_01493 2.3e-96 K Helix-turn-helix domain
NIDDKIGC_01494 2.3e-139 K sequence-specific DNA binding
NIDDKIGC_01495 3.5e-88 S AAA domain
NIDDKIGC_01497 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
NIDDKIGC_01498 3e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
NIDDKIGC_01499 2.6e-44 S MazG-like family
NIDDKIGC_01500 0.0 N Uncharacterized conserved protein (DUF2075)
NIDDKIGC_01501 0.0 pepN 3.4.11.2 E aminopeptidase
NIDDKIGC_01502 4.1e-101 G Glycogen debranching enzyme
NIDDKIGC_01503 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
NIDDKIGC_01504 1.3e-155 yjdB S Domain of unknown function (DUF4767)
NIDDKIGC_01505 7e-147 Q Fumarylacetoacetate (FAA) hydrolase family
NIDDKIGC_01506 5.3e-72 asp2 S Asp23 family, cell envelope-related function
NIDDKIGC_01507 8.7e-72 asp S Asp23 family, cell envelope-related function
NIDDKIGC_01508 7.2e-23
NIDDKIGC_01509 2.6e-84
NIDDKIGC_01510 1.6e-36 S Transglycosylase associated protein
NIDDKIGC_01511 0.0 XK27_09800 I Acyltransferase family
NIDDKIGC_01512 7.4e-38 S MORN repeat
NIDDKIGC_01513 6.7e-164 S Cysteine-rich secretory protein family
NIDDKIGC_01514 7.1e-234 EGP Major facilitator Superfamily
NIDDKIGC_01515 4.2e-56 hxlR K HxlR-like helix-turn-helix
NIDDKIGC_01516 2e-110 XK27_07075 V CAAX protease self-immunity
NIDDKIGC_01517 1.7e-63 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_01518 6.2e-50
NIDDKIGC_01519 2.6e-61
NIDDKIGC_01520 8.9e-23 L hmm pf00665
NIDDKIGC_01521 6.9e-29 L hmm pf00665
NIDDKIGC_01522 2e-18 L hmm pf00665
NIDDKIGC_01523 2.1e-35 L Helix-turn-helix domain
NIDDKIGC_01525 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
NIDDKIGC_01527 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NIDDKIGC_01528 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
NIDDKIGC_01529 1.7e-165 fabK 1.3.1.9 S Nitronate monooxygenase
NIDDKIGC_01530 0.0 helD 3.6.4.12 L DNA helicase
NIDDKIGC_01531 7.7e-112 dedA S SNARE associated Golgi protein
NIDDKIGC_01532 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
NIDDKIGC_01533 0.0 yjbQ P TrkA C-terminal domain protein
NIDDKIGC_01534 4.7e-125 pgm3 G Phosphoglycerate mutase family
NIDDKIGC_01535 4.7e-128 pgm3 G Phosphoglycerate mutase family
NIDDKIGC_01536 1.2e-26
NIDDKIGC_01537 1.3e-48 sugE U Multidrug resistance protein
NIDDKIGC_01538 6.4e-78 3.6.1.55 F NUDIX domain
NIDDKIGC_01539 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NIDDKIGC_01540 7.1e-98 K Bacterial regulatory proteins, tetR family
NIDDKIGC_01541 3.8e-85 S membrane transporter protein
NIDDKIGC_01542 1.2e-208 EGP Major facilitator Superfamily
NIDDKIGC_01543 2e-71 K MarR family
NIDDKIGC_01544 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
NIDDKIGC_01545 4.8e-73 mgrA K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_01546 2.7e-244 steT E amino acid
NIDDKIGC_01547 4.6e-140 G YdjC-like protein
NIDDKIGC_01548 1e-257 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
NIDDKIGC_01549 4.7e-154 K CAT RNA binding domain
NIDDKIGC_01550 2.6e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIDDKIGC_01551 4e-108 glnP P ABC transporter permease
NIDDKIGC_01552 1.3e-108 gluC P ABC transporter permease
NIDDKIGC_01553 7.8e-149 glnH ET ABC transporter substrate-binding protein
NIDDKIGC_01554 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIDDKIGC_01556 3.6e-41
NIDDKIGC_01557 3.3e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIDDKIGC_01558 1.1e-209 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NIDDKIGC_01559 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
NIDDKIGC_01560 4.9e-148
NIDDKIGC_01561 7.1e-12 3.2.1.14 GH18
NIDDKIGC_01562 1.3e-81 zur P Belongs to the Fur family
NIDDKIGC_01563 6.3e-105 gmk2 2.7.4.8 F Guanylate kinase
NIDDKIGC_01564 1.8e-19
NIDDKIGC_01565 1.7e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NIDDKIGC_01566 9.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NIDDKIGC_01567 2.5e-88
NIDDKIGC_01568 8.2e-252 yfnA E Amino Acid
NIDDKIGC_01569 5.8e-46
NIDDKIGC_01570 5e-69 O OsmC-like protein
NIDDKIGC_01571 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NIDDKIGC_01572 0.0 oatA I Acyltransferase
NIDDKIGC_01573 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIDDKIGC_01574 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NIDDKIGC_01575 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_01576 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NIDDKIGC_01577 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_01578 1.2e-225 pbuG S permease
NIDDKIGC_01579 1.5e-19
NIDDKIGC_01580 1.3e-82 K Transcriptional regulator
NIDDKIGC_01581 5e-153 licD M LicD family
NIDDKIGC_01582 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIDDKIGC_01583 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NIDDKIGC_01584 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIDDKIGC_01585 1.8e-241 EGP Major facilitator Superfamily
NIDDKIGC_01586 1.1e-89 V VanZ like family
NIDDKIGC_01587 1.5e-33
NIDDKIGC_01588 1.9e-71 spxA 1.20.4.1 P ArsC family
NIDDKIGC_01590 2.5e-141
NIDDKIGC_01591 7.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIDDKIGC_01592 1.2e-33 G Transmembrane secretion effector
NIDDKIGC_01593 9.2e-139 EGP Transmembrane secretion effector
NIDDKIGC_01594 3e-131 1.5.1.39 C nitroreductase
NIDDKIGC_01595 3e-72
NIDDKIGC_01596 1.5e-52
NIDDKIGC_01597 1.3e-206 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NIDDKIGC_01598 1.1e-104 K Bacterial regulatory proteins, tetR family
NIDDKIGC_01599 1.3e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_01600 1.3e-122 yliE T EAL domain
NIDDKIGC_01601 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NIDDKIGC_01602 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NIDDKIGC_01603 1.6e-129 ybbR S YbbR-like protein
NIDDKIGC_01604 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NIDDKIGC_01605 7.1e-121 S Protein of unknown function (DUF1361)
NIDDKIGC_01606 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
NIDDKIGC_01607 0.0 yjcE P Sodium proton antiporter
NIDDKIGC_01608 6.2e-168 murB 1.3.1.98 M Cell wall formation
NIDDKIGC_01609 1.2e-158 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NIDDKIGC_01610 8.1e-153 xth 3.1.11.2 L exodeoxyribonuclease III
NIDDKIGC_01611 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
NIDDKIGC_01612 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
NIDDKIGC_01613 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NIDDKIGC_01614 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NIDDKIGC_01615 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NIDDKIGC_01616 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_01617 5.1e-104 yxjI
NIDDKIGC_01618 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIDDKIGC_01619 1.5e-256 glnP P ABC transporter
NIDDKIGC_01620 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
NIDDKIGC_01621 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NIDDKIGC_01622 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NIDDKIGC_01623 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
NIDDKIGC_01624 1.2e-30 secG U Preprotein translocase
NIDDKIGC_01625 6.6e-295 clcA P chloride
NIDDKIGC_01626 1.3e-133
NIDDKIGC_01627 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NIDDKIGC_01628 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NIDDKIGC_01629 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NIDDKIGC_01630 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NIDDKIGC_01631 7.3e-189 cggR K Putative sugar-binding domain
NIDDKIGC_01632 4.2e-245 rpoN K Sigma-54 factor, core binding domain
NIDDKIGC_01634 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NIDDKIGC_01635 3e-176 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIDDKIGC_01636 7.5e-305 oppA E ABC transporter, substratebinding protein
NIDDKIGC_01637 1.1e-167 whiA K May be required for sporulation
NIDDKIGC_01638 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NIDDKIGC_01639 1.1e-161 rapZ S Displays ATPase and GTPase activities
NIDDKIGC_01640 9.3e-87 S Short repeat of unknown function (DUF308)
NIDDKIGC_01641 1.6e-263 argH 4.3.2.1 E argininosuccinate lyase
NIDDKIGC_01642 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NIDDKIGC_01643 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NIDDKIGC_01644 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NIDDKIGC_01645 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NIDDKIGC_01646 1.2e-117 yfbR S HD containing hydrolase-like enzyme
NIDDKIGC_01647 9e-207 norA EGP Major facilitator Superfamily
NIDDKIGC_01648 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
NIDDKIGC_01649 4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
NIDDKIGC_01650 3.3e-132 yliE T Putative diguanylate phosphodiesterase
NIDDKIGC_01651 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NIDDKIGC_01652 1.5e-50 S Protein of unknown function (DUF3290)
NIDDKIGC_01653 2e-109 yviA S Protein of unknown function (DUF421)
NIDDKIGC_01654 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NIDDKIGC_01655 1e-132 2.7.7.65 T diguanylate cyclase activity
NIDDKIGC_01656 0.0 ydaN S Bacterial cellulose synthase subunit
NIDDKIGC_01657 6.8e-218 ydaM M Glycosyl transferase family group 2
NIDDKIGC_01658 1e-205 S Protein conserved in bacteria
NIDDKIGC_01659 1.2e-245
NIDDKIGC_01660 7.3e-163 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
NIDDKIGC_01661 1.4e-270 nox C NADH oxidase
NIDDKIGC_01662 1.9e-124 yliE T Putative diguanylate phosphodiesterase
NIDDKIGC_01663 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NIDDKIGC_01664 1.9e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NIDDKIGC_01665 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NIDDKIGC_01666 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NIDDKIGC_01667 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
NIDDKIGC_01668 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
NIDDKIGC_01669 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
NIDDKIGC_01670 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIDDKIGC_01671 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NIDDKIGC_01672 1.5e-155 pstA P Phosphate transport system permease protein PstA
NIDDKIGC_01673 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
NIDDKIGC_01674 1.1e-150 pstS P Phosphate
NIDDKIGC_01675 3.5e-250 phoR 2.7.13.3 T Histidine kinase
NIDDKIGC_01676 1.5e-132 K response regulator
NIDDKIGC_01677 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
NIDDKIGC_01678 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NIDDKIGC_01679 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NIDDKIGC_01680 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NIDDKIGC_01681 7.5e-126 comFC S Competence protein
NIDDKIGC_01682 2.8e-257 comFA L Helicase C-terminal domain protein
NIDDKIGC_01683 1.7e-114 yvyE 3.4.13.9 S YigZ family
NIDDKIGC_01684 4.3e-145 pstS P Phosphate
NIDDKIGC_01685 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
NIDDKIGC_01686 0.0 ydaO E amino acid
NIDDKIGC_01687 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NIDDKIGC_01688 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NIDDKIGC_01689 4.6e-109 ydiL S CAAX protease self-immunity
NIDDKIGC_01690 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NIDDKIGC_01691 5.7e-307 uup S ABC transporter, ATP-binding protein
NIDDKIGC_01692 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NIDDKIGC_01693 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NIDDKIGC_01694 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NIDDKIGC_01695 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NIDDKIGC_01696 1.9e-189 phnD P Phosphonate ABC transporter
NIDDKIGC_01697 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NIDDKIGC_01698 2.3e-137 phnE 3.6.1.63 U Phosphonate ABC transporter permease
NIDDKIGC_01699 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
NIDDKIGC_01700 6.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
NIDDKIGC_01701 6.1e-210 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
NIDDKIGC_01702 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIDDKIGC_01703 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
NIDDKIGC_01704 5.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NIDDKIGC_01705 1e-57 yabA L Involved in initiation control of chromosome replication
NIDDKIGC_01706 3.3e-186 holB 2.7.7.7 L DNA polymerase III
NIDDKIGC_01707 2.4e-53 yaaQ S Cyclic-di-AMP receptor
NIDDKIGC_01708 1.9e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NIDDKIGC_01709 2.2e-38 yaaL S Protein of unknown function (DUF2508)
NIDDKIGC_01710 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NIDDKIGC_01711 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NIDDKIGC_01712 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NIDDKIGC_01713 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NIDDKIGC_01714 2.8e-108 rsmC 2.1.1.172 J Methyltransferase
NIDDKIGC_01715 6.5e-37 nrdH O Glutaredoxin
NIDDKIGC_01716 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIDDKIGC_01717 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NIDDKIGC_01718 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
NIDDKIGC_01719 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NIDDKIGC_01720 1.2e-38 L nuclease
NIDDKIGC_01721 4.9e-179 F DNA/RNA non-specific endonuclease
NIDDKIGC_01722 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NIDDKIGC_01723 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NIDDKIGC_01724 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NIDDKIGC_01725 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NIDDKIGC_01726 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_01727 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
NIDDKIGC_01728 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NIDDKIGC_01729 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NIDDKIGC_01730 2.4e-101 sigH K Sigma-70 region 2
NIDDKIGC_01731 5.3e-98 yacP S YacP-like NYN domain
NIDDKIGC_01732 2.2e-137 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NIDDKIGC_01733 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NIDDKIGC_01734 2e-269 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIDDKIGC_01735 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NIDDKIGC_01736 3.7e-205 yacL S domain protein
NIDDKIGC_01737 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NIDDKIGC_01738 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NIDDKIGC_01739 1.6e-51 HA62_12640 S GCN5-related N-acetyl-transferase
NIDDKIGC_01740 2.1e-123 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NIDDKIGC_01741 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
NIDDKIGC_01742 1.8e-113 zmp2 O Zinc-dependent metalloprotease
NIDDKIGC_01743 4.7e-128 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIDDKIGC_01744 1.7e-177 EG EamA-like transporter family
NIDDKIGC_01745 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
NIDDKIGC_01746 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIDDKIGC_01747 1.6e-135 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
NIDDKIGC_01748 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NIDDKIGC_01749 1.2e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
NIDDKIGC_01750 1.4e-63 accB 2.3.1.12 I Biotin-requiring enzyme
NIDDKIGC_01751 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NIDDKIGC_01752 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
NIDDKIGC_01753 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
NIDDKIGC_01754 0.0 levR K Sigma-54 interaction domain
NIDDKIGC_01755 4.7e-64 S Domain of unknown function (DUF956)
NIDDKIGC_01756 3.6e-171 manN G system, mannose fructose sorbose family IID component
NIDDKIGC_01757 3.4e-133 manY G PTS system
NIDDKIGC_01758 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NIDDKIGC_01759 9.3e-155 G Peptidase_C39 like family
NIDDKIGC_01761 3.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NIDDKIGC_01762 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NIDDKIGC_01763 5.7e-82 ydcK S Belongs to the SprT family
NIDDKIGC_01764 0.0 yhgF K Tex-like protein N-terminal domain protein
NIDDKIGC_01765 8.9e-72
NIDDKIGC_01766 0.0 pacL 3.6.3.8 P P-type ATPase
NIDDKIGC_01767 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NIDDKIGC_01768 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIDDKIGC_01769 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NIDDKIGC_01770 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
NIDDKIGC_01771 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NIDDKIGC_01772 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NIDDKIGC_01773 3.7e-151 pnuC H nicotinamide mononucleotide transporter
NIDDKIGC_01774 4.7e-194 ybiR P Citrate transporter
NIDDKIGC_01775 1.1e-166 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NIDDKIGC_01776 2.5e-53 S Cupin domain
NIDDKIGC_01777 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
NIDDKIGC_01781 2e-151 yjjH S Calcineurin-like phosphoesterase
NIDDKIGC_01782 3e-252 dtpT U amino acid peptide transporter
NIDDKIGC_01785 1.5e-42 S COG NOG38524 non supervised orthologous group
NIDDKIGC_01788 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NIDDKIGC_01789 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIDDKIGC_01790 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NIDDKIGC_01791 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NIDDKIGC_01792 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NIDDKIGC_01793 1.9e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NIDDKIGC_01794 3.1e-74 yabR J RNA binding
NIDDKIGC_01795 1.1e-63 divIC D Septum formation initiator
NIDDKIGC_01797 2.2e-42 yabO J S4 domain protein
NIDDKIGC_01798 3.3e-289 yabM S Polysaccharide biosynthesis protein
NIDDKIGC_01799 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NIDDKIGC_01800 4.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NIDDKIGC_01801 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NIDDKIGC_01802 1.4e-264 S Putative peptidoglycan binding domain
NIDDKIGC_01803 2.1e-114 S (CBS) domain
NIDDKIGC_01804 4.1e-84 S QueT transporter
NIDDKIGC_01805 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NIDDKIGC_01806 2.7e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine
NIDDKIGC_01807 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
NIDDKIGC_01808 1.5e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NIDDKIGC_01809 1.2e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NIDDKIGC_01810 4.8e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIDDKIGC_01811 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIDDKIGC_01812 5e-134 P ATPases associated with a variety of cellular activities
NIDDKIGC_01813 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
NIDDKIGC_01814 2.9e-193 P ABC transporter, substratebinding protein
NIDDKIGC_01815 0.0 kup P Transport of potassium into the cell
NIDDKIGC_01816 2.3e-63 ndoA L Toxic component of a toxin-antitoxin (TA) module
NIDDKIGC_01817 4.9e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NIDDKIGC_01818 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NIDDKIGC_01819 1.1e-257 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NIDDKIGC_01820 1.2e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NIDDKIGC_01821 2e-146
NIDDKIGC_01822 2.1e-139 htpX O Belongs to the peptidase M48B family
NIDDKIGC_01823 1.7e-91 lemA S LemA family
NIDDKIGC_01824 9.2e-127 srtA 3.4.22.70 M sortase family
NIDDKIGC_01825 3.2e-214 J translation release factor activity
NIDDKIGC_01826 7.8e-41 rpmE2 J Ribosomal protein L31
NIDDKIGC_01827 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NIDDKIGC_01828 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NIDDKIGC_01829 5.1e-27
NIDDKIGC_01830 2.9e-131 S YheO-like PAS domain
NIDDKIGC_01831 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NIDDKIGC_01832 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NIDDKIGC_01833 3.1e-229 tdcC E amino acid
NIDDKIGC_01834 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NIDDKIGC_01835 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NIDDKIGC_01836 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NIDDKIGC_01837 3.8e-78 ywiB S Domain of unknown function (DUF1934)
NIDDKIGC_01838 3.9e-156 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
NIDDKIGC_01839 9e-264 ywfO S HD domain protein
NIDDKIGC_01840 1.7e-148 yxeH S hydrolase
NIDDKIGC_01841 4.1e-125
NIDDKIGC_01842 2.5e-181 S DUF218 domain
NIDDKIGC_01843 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NIDDKIGC_01844 7.4e-152 bla1 3.5.2.6 V Beta-lactamase enzyme family
NIDDKIGC_01845 3.6e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NIDDKIGC_01846 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NIDDKIGC_01847 9.2e-131 znuB U ABC 3 transport family
NIDDKIGC_01848 9.8e-129 fhuC 3.6.3.35 P ABC transporter
NIDDKIGC_01849 1.3e-181 S Prolyl oligopeptidase family
NIDDKIGC_01850 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NIDDKIGC_01851 3.2e-37 veg S Biofilm formation stimulator VEG
NIDDKIGC_01852 8e-160 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NIDDKIGC_01853 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NIDDKIGC_01854 1.5e-146 tatD L hydrolase, TatD family
NIDDKIGC_01855 1.9e-159 bcr1 EGP Major facilitator Superfamily
NIDDKIGC_01856 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NIDDKIGC_01857 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
NIDDKIGC_01858 2.9e-159 yunF F Protein of unknown function DUF72
NIDDKIGC_01859 1.1e-132 cobB K SIR2 family
NIDDKIGC_01860 5e-176
NIDDKIGC_01861 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
NIDDKIGC_01862 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
NIDDKIGC_01863 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIDDKIGC_01864 4.1e-133 K Helix-turn-helix domain, rpiR family
NIDDKIGC_01865 1e-162 GK ROK family
NIDDKIGC_01866 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_01867 1.5e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01868 2.6e-76 S Domain of unknown function (DUF3284)
NIDDKIGC_01869 3.9e-24
NIDDKIGC_01870 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01871 9e-130 K UbiC transcription regulator-associated domain protein
NIDDKIGC_01872 1.7e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NIDDKIGC_01873 1.1e-141 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
NIDDKIGC_01874 0.0 helD 3.6.4.12 L DNA helicase
NIDDKIGC_01875 1.8e-30
NIDDKIGC_01876 9.6e-113 S CAAX protease self-immunity
NIDDKIGC_01877 7.1e-108 V CAAX protease self-immunity
NIDDKIGC_01878 1.7e-117 ypbD S CAAX protease self-immunity
NIDDKIGC_01879 1e-109 S CAAX protease self-immunity
NIDDKIGC_01880 1.7e-241 mesE M Transport protein ComB
NIDDKIGC_01881 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NIDDKIGC_01882 6.7e-23
NIDDKIGC_01883 2.4e-22 plnF
NIDDKIGC_01884 6.3e-129 S CAAX protease self-immunity
NIDDKIGC_01885 2.5e-130 plnD K LytTr DNA-binding domain
NIDDKIGC_01886 4.1e-99 2.7.13.3 T GHKL domain
NIDDKIGC_01888 5.3e-116
NIDDKIGC_01891 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIDDKIGC_01892 1e-254 brnQ U Component of the transport system for branched-chain amino acids
NIDDKIGC_01893 1.4e-150 S hydrolase
NIDDKIGC_01894 7.3e-166 K Transcriptional regulator
NIDDKIGC_01895 3.4e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_01896 4.8e-197 uhpT EGP Major facilitator Superfamily
NIDDKIGC_01897 8.1e-119 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIDDKIGC_01898 1.3e-18 S Barstar (barnase inhibitor)
NIDDKIGC_01899 1.4e-61
NIDDKIGC_01900 1.5e-16
NIDDKIGC_01901 5.1e-08
NIDDKIGC_01902 8.4e-33
NIDDKIGC_01903 5.9e-22 S Barstar (barnase inhibitor)
NIDDKIGC_01904 1.2e-29 M dTDP-4-dehydrorhamnose reductase activity
NIDDKIGC_01905 0.0 M domain protein
NIDDKIGC_01906 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_01907 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
NIDDKIGC_01908 1.5e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NIDDKIGC_01909 7.5e-255 gshR 1.8.1.7 C Glutathione reductase
NIDDKIGC_01910 1.4e-178 proV E ABC transporter, ATP-binding protein
NIDDKIGC_01911 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NIDDKIGC_01912 1.1e-77 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
NIDDKIGC_01913 2.5e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_01914 3.5e-174 rihC 3.2.2.1 F Nucleoside
NIDDKIGC_01915 5.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NIDDKIGC_01916 7.1e-80
NIDDKIGC_01917 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
NIDDKIGC_01918 4e-231 flhF N Uncharacterized conserved protein (DUF2075)
NIDDKIGC_01919 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
NIDDKIGC_01920 3.2e-54 ypaA S Protein of unknown function (DUF1304)
NIDDKIGC_01921 7.1e-310 mco Q Multicopper oxidase
NIDDKIGC_01922 1.8e-119 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NIDDKIGC_01923 1.5e-100 zmp1 O Zinc-dependent metalloprotease
NIDDKIGC_01924 3.7e-44
NIDDKIGC_01925 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
NIDDKIGC_01926 4.7e-241 amtB P ammonium transporter
NIDDKIGC_01927 2.1e-258 P Major Facilitator Superfamily
NIDDKIGC_01928 2.8e-85 K Transcriptional regulator PadR-like family
NIDDKIGC_01929 8.4e-44
NIDDKIGC_01930 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NIDDKIGC_01931 3.5e-154 tagG U Transport permease protein
NIDDKIGC_01932 7.1e-217
NIDDKIGC_01933 4.4e-225 mtnE 2.6.1.83 E Aminotransferase
NIDDKIGC_01934 1.9e-60 S CHY zinc finger
NIDDKIGC_01935 1.6e-177 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NIDDKIGC_01936 6.8e-96 bioY S BioY family
NIDDKIGC_01937 3e-40
NIDDKIGC_01938 1.1e-280 pipD E Dipeptidase
NIDDKIGC_01939 3e-30
NIDDKIGC_01940 3e-122 qmcA O prohibitin homologues
NIDDKIGC_01941 2.3e-240 xylP1 G MFS/sugar transport protein
NIDDKIGC_01943 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NIDDKIGC_01944 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
NIDDKIGC_01945 4.9e-190
NIDDKIGC_01946 2e-163 ytrB V ABC transporter
NIDDKIGC_01947 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
NIDDKIGC_01948 8.1e-22
NIDDKIGC_01949 8e-91 K acetyltransferase
NIDDKIGC_01950 1e-84 K GNAT family
NIDDKIGC_01951 1.1e-83 6.3.3.2 S ASCH
NIDDKIGC_01952 8.5e-96 puuR K Cupin domain
NIDDKIGC_01953 1.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NIDDKIGC_01954 2e-149 potB P ABC transporter permease
NIDDKIGC_01955 3.4e-141 potC P ABC transporter permease
NIDDKIGC_01956 4e-206 potD P ABC transporter
NIDDKIGC_01957 6.2e-39
NIDDKIGC_01958 7.8e-227 ndh 1.6.99.3 C NADH dehydrogenase
NIDDKIGC_01959 1.7e-75 K Transcriptional regulator
NIDDKIGC_01960 7.2e-77 elaA S GNAT family
NIDDKIGC_01961 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIDDKIGC_01962 2.9e-55
NIDDKIGC_01963 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
NIDDKIGC_01964 3.7e-131
NIDDKIGC_01965 1.8e-175 sepS16B
NIDDKIGC_01966 7.4e-67 gcvH E Glycine cleavage H-protein
NIDDKIGC_01967 1.8e-52 lytE M LysM domain protein
NIDDKIGC_01968 8.5e-52 M Lysin motif
NIDDKIGC_01969 4.5e-121 S CAAX protease self-immunity
NIDDKIGC_01970 2.5e-114 V CAAX protease self-immunity
NIDDKIGC_01971 7.1e-121 yclH V ABC transporter
NIDDKIGC_01972 1.7e-194 yclI V MacB-like periplasmic core domain
NIDDKIGC_01973 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
NIDDKIGC_01974 2.9e-107 tag 3.2.2.20 L glycosylase
NIDDKIGC_01975 0.0 ydgH S MMPL family
NIDDKIGC_01976 3.1e-104 K transcriptional regulator
NIDDKIGC_01977 2.7e-123 2.7.6.5 S RelA SpoT domain protein
NIDDKIGC_01978 1.3e-47
NIDDKIGC_01979 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
NIDDKIGC_01980 1.9e-103 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NIDDKIGC_01981 2.1e-41
NIDDKIGC_01982 9.9e-57
NIDDKIGC_01983 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_01984 2.1e-129 yidA K Helix-turn-helix domain, rpiR family
NIDDKIGC_01985 1.8e-49
NIDDKIGC_01986 6.4e-128 K Transcriptional regulatory protein, C terminal
NIDDKIGC_01987 2.3e-251 T PhoQ Sensor
NIDDKIGC_01988 3.3e-65 K helix_turn_helix, mercury resistance
NIDDKIGC_01989 6.3e-252 ydiC1 EGP Major facilitator Superfamily
NIDDKIGC_01990 1e-40
NIDDKIGC_01991 5.2e-42
NIDDKIGC_01992 5.5e-118
NIDDKIGC_01993 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
NIDDKIGC_01994 4.3e-121 K Bacterial regulatory proteins, tetR family
NIDDKIGC_01995 1.8e-72 K Transcriptional regulator
NIDDKIGC_01996 1.6e-70
NIDDKIGC_01997 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NIDDKIGC_01998 7e-168 S Psort location CytoplasmicMembrane, score
NIDDKIGC_01999 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NIDDKIGC_02000 2.1e-235 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
NIDDKIGC_02001 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NIDDKIGC_02002 1.4e-144
NIDDKIGC_02003 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
NIDDKIGC_02004 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02005 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NIDDKIGC_02006 3.5e-129 treR K UTRA
NIDDKIGC_02007 1.7e-42
NIDDKIGC_02008 7.3e-43 S Protein of unknown function (DUF2089)
NIDDKIGC_02009 4.3e-141 pnuC H nicotinamide mononucleotide transporter
NIDDKIGC_02010 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
NIDDKIGC_02011 4.5e-166 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NIDDKIGC_02012 2e-211 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NIDDKIGC_02013 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
NIDDKIGC_02014 1.7e-190 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
NIDDKIGC_02015 8.2e-73 4.1.2.14 S KDGP aldolase
NIDDKIGC_02016 2.7e-39 4.1.2.14 S KDGP aldolase
NIDDKIGC_02017 5.2e-201 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
NIDDKIGC_02018 7.8e-213 dho 3.5.2.3 S Amidohydrolase family
NIDDKIGC_02019 4.2e-211 S Bacterial protein of unknown function (DUF871)
NIDDKIGC_02020 1e-38
NIDDKIGC_02021 4.8e-233 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_02022 2.5e-124 K helix_turn_helix gluconate operon transcriptional repressor
NIDDKIGC_02023 5.4e-98 yieF S NADPH-dependent FMN reductase
NIDDKIGC_02024 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
NIDDKIGC_02025 6.6e-81 ndk 2.7.4.6 F Belongs to the NDK family
NIDDKIGC_02026 2e-62
NIDDKIGC_02027 6.6e-96
NIDDKIGC_02028 1.1e-50
NIDDKIGC_02029 6.2e-57 trxA1 O Belongs to the thioredoxin family
NIDDKIGC_02030 2.9e-75
NIDDKIGC_02031 4.3e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NIDDKIGC_02032 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_02033 0.0 mtlR K Mga helix-turn-helix domain
NIDDKIGC_02034 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_02035 5.7e-277 pipD E Dipeptidase
NIDDKIGC_02036 3.6e-99 K Helix-turn-helix domain
NIDDKIGC_02037 3.5e-224 1.3.5.4 C FAD dependent oxidoreductase
NIDDKIGC_02038 2e-174 P Major Facilitator Superfamily
NIDDKIGC_02039 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NIDDKIGC_02040 4.7e-31 ygzD K Transcriptional
NIDDKIGC_02041 6.7e-69
NIDDKIGC_02042 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NIDDKIGC_02043 1.4e-158 dkgB S reductase
NIDDKIGC_02044 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NIDDKIGC_02045 3.1e-101 S ABC transporter permease
NIDDKIGC_02046 1.4e-259 P ABC transporter
NIDDKIGC_02047 1.8e-116 P cobalt transport
NIDDKIGC_02048 3.6e-261 S ATPases associated with a variety of cellular activities
NIDDKIGC_02049 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIDDKIGC_02050 1.9e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NIDDKIGC_02052 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NIDDKIGC_02053 4.9e-162 FbpA K Domain of unknown function (DUF814)
NIDDKIGC_02054 1.9e-10 S Domain of unknown function (DU1801)
NIDDKIGC_02055 4.9e-34
NIDDKIGC_02056 1e-179 yghZ C Aldo keto reductase family protein
NIDDKIGC_02057 3e-113 pgm1 G phosphoglycerate mutase
NIDDKIGC_02058 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NIDDKIGC_02059 1.1e-214 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NIDDKIGC_02060 2.6e-79 yiaC K Acetyltransferase (GNAT) domain
NIDDKIGC_02061 3.5e-310 oppA E ABC transporter, substratebinding protein
NIDDKIGC_02062 0.0 oppA E ABC transporter, substratebinding protein
NIDDKIGC_02063 2.1e-157 hipB K Helix-turn-helix
NIDDKIGC_02065 0.0 3.6.4.13 M domain protein
NIDDKIGC_02066 3.6e-123 mleR K LysR substrate binding domain
NIDDKIGC_02067 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NIDDKIGC_02068 1.1e-217 nhaC C Na H antiporter NhaC
NIDDKIGC_02069 1.3e-165 3.5.1.10 C nadph quinone reductase
NIDDKIGC_02070 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NIDDKIGC_02071 9.1e-173 scrR K Transcriptional regulator, LacI family
NIDDKIGC_02072 1.4e-305 scrB 3.2.1.26 GH32 G invertase
NIDDKIGC_02073 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NIDDKIGC_02074 0.0 rafA 3.2.1.22 G alpha-galactosidase
NIDDKIGC_02075 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NIDDKIGC_02076 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
NIDDKIGC_02077 0.0 3.2.1.96 G Glycosyl hydrolase family 85
NIDDKIGC_02078 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NIDDKIGC_02079 4e-209 msmK P Belongs to the ABC transporter superfamily
NIDDKIGC_02080 1.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
NIDDKIGC_02081 5.3e-150 malA S maltodextrose utilization protein MalA
NIDDKIGC_02082 1.4e-161 malD P ABC transporter permease
NIDDKIGC_02083 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
NIDDKIGC_02084 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
NIDDKIGC_02085 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NIDDKIGC_02086 2e-180 yvdE K helix_turn _helix lactose operon repressor
NIDDKIGC_02087 2.9e-190 malR K Transcriptional regulator, LacI family
NIDDKIGC_02088 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_02089 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
NIDDKIGC_02090 1.9e-101 dhaL 2.7.1.121 S Dak2
NIDDKIGC_02091 4.3e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NIDDKIGC_02092 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
NIDDKIGC_02093 1.9e-92 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02095 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
NIDDKIGC_02096 1.4e-276 C Electron transfer flavoprotein FAD-binding domain
NIDDKIGC_02097 1.6e-117 K Transcriptional regulator
NIDDKIGC_02098 3.5e-299 M Exporter of polyketide antibiotics
NIDDKIGC_02099 2.2e-168 yjjC V ABC transporter
NIDDKIGC_02100 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
NIDDKIGC_02101 9.1e-89
NIDDKIGC_02102 2.6e-149
NIDDKIGC_02103 1.7e-142
NIDDKIGC_02104 8.3e-54 K Transcriptional regulator PadR-like family
NIDDKIGC_02105 1.6e-129 K UbiC transcription regulator-associated domain protein
NIDDKIGC_02107 2.5e-98 S UPF0397 protein
NIDDKIGC_02108 0.0 ykoD P ABC transporter, ATP-binding protein
NIDDKIGC_02109 1.6e-149 cbiQ P cobalt transport
NIDDKIGC_02110 1.4e-206 C Oxidoreductase
NIDDKIGC_02111 8e-253
NIDDKIGC_02112 1.9e-51
NIDDKIGC_02113 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
NIDDKIGC_02114 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
NIDDKIGC_02115 1.2e-165 1.1.1.65 C Aldo keto reductase
NIDDKIGC_02116 3.4e-160 S reductase
NIDDKIGC_02118 8.1e-216 yeaN P Transporter, major facilitator family protein
NIDDKIGC_02119 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_02120 4.7e-227 mdtG EGP Major facilitator Superfamily
NIDDKIGC_02121 1.2e-67 K LytTr DNA-binding domain
NIDDKIGC_02122 1e-81 S Protein of unknown function (DUF3021)
NIDDKIGC_02123 6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
NIDDKIGC_02124 1.1e-75 papX3 K Transcriptional regulator
NIDDKIGC_02125 2.1e-111 S NADPH-dependent FMN reductase
NIDDKIGC_02126 1.6e-28 KT PspC domain
NIDDKIGC_02127 5.8e-143 2.4.2.3 F Phosphorylase superfamily
NIDDKIGC_02128 0.0 pacL1 P P-type ATPase
NIDDKIGC_02129 1.6e-99 S CRISPR-associated protein (Cas_Csn2)
NIDDKIGC_02130 6.3e-48 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIDDKIGC_02131 7.1e-156 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NIDDKIGC_02132 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NIDDKIGC_02133 9.5e-149 ydjP I Alpha/beta hydrolase family
NIDDKIGC_02134 7.6e-121
NIDDKIGC_02135 2.6e-250 yifK E Amino acid permease
NIDDKIGC_02136 9.9e-85 F NUDIX domain
NIDDKIGC_02137 4e-303 L HIRAN domain
NIDDKIGC_02138 5.1e-136 S peptidase C26
NIDDKIGC_02139 1.9e-204 cytX U Belongs to the purine-cytosine permease (2.A.39) family
NIDDKIGC_02140 2.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NIDDKIGC_02141 9.1e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NIDDKIGC_02142 3.2e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NIDDKIGC_02143 8.7e-176 1.6.5.5 C Zinc-binding dehydrogenase
NIDDKIGC_02144 2.8e-151 larE S NAD synthase
NIDDKIGC_02145 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_02146 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
NIDDKIGC_02147 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
NIDDKIGC_02148 2.4e-125 larB S AIR carboxylase
NIDDKIGC_02149 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
NIDDKIGC_02150 4.2e-121 K Crp-like helix-turn-helix domain
NIDDKIGC_02151 4.8e-182 nikMN P PDGLE domain
NIDDKIGC_02152 2.6e-149 P Cobalt transport protein
NIDDKIGC_02153 3.9e-128 cbiO P ABC transporter
NIDDKIGC_02154 4.8e-40
NIDDKIGC_02155 3.1e-139 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
NIDDKIGC_02157 9.1e-141
NIDDKIGC_02158 2.3e-311 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
NIDDKIGC_02159 6e-76
NIDDKIGC_02160 1e-139 S Belongs to the UPF0246 family
NIDDKIGC_02161 8.7e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NIDDKIGC_02162 3.9e-235 mepA V MATE efflux family protein
NIDDKIGC_02163 1.7e-49 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_02164 5.4e-181 1.1.1.1 C nadph quinone reductase
NIDDKIGC_02165 2e-126 hchA S DJ-1/PfpI family
NIDDKIGC_02166 3.6e-93 MA20_25245 K FR47-like protein
NIDDKIGC_02167 3.6e-152 EG EamA-like transporter family
NIDDKIGC_02168 2.7e-61 S Protein of unknown function
NIDDKIGC_02169 8.2e-39 S Protein of unknown function
NIDDKIGC_02170 0.0 tetP J elongation factor G
NIDDKIGC_02171 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NIDDKIGC_02172 5.5e-172 yobV1 K WYL domain
NIDDKIGC_02173 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NIDDKIGC_02174 2.9e-81 6.3.3.2 S ASCH
NIDDKIGC_02175 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
NIDDKIGC_02176 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
NIDDKIGC_02177 7.4e-250 yjjP S Putative threonine/serine exporter
NIDDKIGC_02178 3.3e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIDDKIGC_02179 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NIDDKIGC_02180 1.3e-290 QT PucR C-terminal helix-turn-helix domain
NIDDKIGC_02181 4.4e-79 drgA C Nitroreductase family
NIDDKIGC_02182 2.8e-29 drgA C Nitroreductase family
NIDDKIGC_02183 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
NIDDKIGC_02184 2.3e-164 ptlF S KR domain
NIDDKIGC_02185 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIDDKIGC_02186 1e-72 C FMN binding
NIDDKIGC_02187 7.3e-65 K LysR family
NIDDKIGC_02188 2.3e-82 K LysR family
NIDDKIGC_02189 1.6e-258 P Sodium:sulfate symporter transmembrane region
NIDDKIGC_02190 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
NIDDKIGC_02191 2e-115 S Elongation factor G-binding protein, N-terminal
NIDDKIGC_02192 2.6e-64 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NIDDKIGC_02193 9.1e-121 pnb C nitroreductase
NIDDKIGC_02194 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NIDDKIGC_02195 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
NIDDKIGC_02196 1.5e-95 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02197 3.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NIDDKIGC_02198 6.8e-173 htrA 3.4.21.107 O serine protease
NIDDKIGC_02199 8.9e-158 vicX 3.1.26.11 S domain protein
NIDDKIGC_02200 2.2e-151 yycI S YycH protein
NIDDKIGC_02201 2.7e-244 yycH S YycH protein
NIDDKIGC_02202 0.0 vicK 2.7.13.3 T Histidine kinase
NIDDKIGC_02203 6.2e-131 K response regulator
NIDDKIGC_02205 1.7e-37
NIDDKIGC_02206 1.6e-31 cspA K Cold shock protein domain
NIDDKIGC_02207 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
NIDDKIGC_02208 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
NIDDKIGC_02209 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NIDDKIGC_02210 1.3e-142 S haloacid dehalogenase-like hydrolase
NIDDKIGC_02212 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
NIDDKIGC_02213 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NIDDKIGC_02214 6.8e-278 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
NIDDKIGC_02215 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
NIDDKIGC_02216 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NIDDKIGC_02217 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NIDDKIGC_02218 1.9e-276 E ABC transporter, substratebinding protein
NIDDKIGC_02220 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NIDDKIGC_02221 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NIDDKIGC_02222 8.8e-226 yttB EGP Major facilitator Superfamily
NIDDKIGC_02223 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NIDDKIGC_02224 1.4e-67 rplI J Binds to the 23S rRNA
NIDDKIGC_02225 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NIDDKIGC_02226 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NIDDKIGC_02227 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NIDDKIGC_02228 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NIDDKIGC_02229 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIDDKIGC_02230 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NIDDKIGC_02231 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NIDDKIGC_02232 5e-37 yaaA S S4 domain protein YaaA
NIDDKIGC_02233 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NIDDKIGC_02234 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NIDDKIGC_02235 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NIDDKIGC_02236 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NIDDKIGC_02237 2.1e-129 jag S R3H domain protein
NIDDKIGC_02238 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NIDDKIGC_02239 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NIDDKIGC_02240 6.9e-93 S Cell surface protein
NIDDKIGC_02241 1.2e-159 S Bacterial protein of unknown function (DUF916)
NIDDKIGC_02243 1.3e-303
NIDDKIGC_02244 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIDDKIGC_02246 1.5e-255 pepC 3.4.22.40 E aminopeptidase
NIDDKIGC_02247 2.4e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
NIDDKIGC_02248 1.2e-157 degV S DegV family
NIDDKIGC_02249 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
NIDDKIGC_02250 3.7e-140 tesE Q hydratase
NIDDKIGC_02251 1.7e-104 padC Q Phenolic acid decarboxylase
NIDDKIGC_02252 2.2e-99 padR K Virulence activator alpha C-term
NIDDKIGC_02253 2.7e-79 T Universal stress protein family
NIDDKIGC_02254 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NIDDKIGC_02255 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
NIDDKIGC_02256 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NIDDKIGC_02257 7.9e-67 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NIDDKIGC_02258 2.7e-160 rbsU U ribose uptake protein RbsU
NIDDKIGC_02259 1.5e-144 IQ NAD dependent epimerase/dehydratase family
NIDDKIGC_02260 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
NIDDKIGC_02261 1.1e-86 gutM K Glucitol operon activator protein (GutM)
NIDDKIGC_02262 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
NIDDKIGC_02263 1.3e-174 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
NIDDKIGC_02264 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NIDDKIGC_02265 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_02266 8.7e-72 K Transcriptional regulator
NIDDKIGC_02267 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_02268 2.3e-201 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NIDDKIGC_02270 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
NIDDKIGC_02271 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
NIDDKIGC_02272 1.8e-12
NIDDKIGC_02273 8.7e-160 2.7.13.3 T GHKL domain
NIDDKIGC_02274 2.8e-134 K LytTr DNA-binding domain
NIDDKIGC_02275 4.9e-78 yneH 1.20.4.1 K ArsC family
NIDDKIGC_02276 1.9e-291 katA 1.11.1.6 C Belongs to the catalase family
NIDDKIGC_02277 9e-13 ytgB S Transglycosylase associated protein
NIDDKIGC_02278 3.6e-11
NIDDKIGC_02279 4.5e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
NIDDKIGC_02280 4.2e-70 S Pyrimidine dimer DNA glycosylase
NIDDKIGC_02281 2.9e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
NIDDKIGC_02282 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NIDDKIGC_02283 3.1e-206 araR K Transcriptional regulator
NIDDKIGC_02284 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
NIDDKIGC_02285 1.7e-306 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
NIDDKIGC_02286 1e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NIDDKIGC_02287 7.8e-266 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NIDDKIGC_02288 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NIDDKIGC_02289 2.6e-70 yueI S Protein of unknown function (DUF1694)
NIDDKIGC_02290 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIDDKIGC_02291 5.2e-123 K DeoR C terminal sensor domain
NIDDKIGC_02292 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIDDKIGC_02293 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_02294 1.1e-231 gatC G PTS system sugar-specific permease component
NIDDKIGC_02295 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
NIDDKIGC_02296 1.3e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
NIDDKIGC_02297 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIDDKIGC_02298 2e-77 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIDDKIGC_02299 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
NIDDKIGC_02300 3.7e-241 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NIDDKIGC_02301 1.8e-113 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NIDDKIGC_02302 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIDDKIGC_02303 7.3e-144 yxeH S hydrolase
NIDDKIGC_02304 9.9e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NIDDKIGC_02306 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NIDDKIGC_02307 6.1e-271 G Major Facilitator
NIDDKIGC_02308 1.1e-173 K Transcriptional regulator, LacI family
NIDDKIGC_02309 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
NIDDKIGC_02310 4.9e-159 licT K CAT RNA binding domain
NIDDKIGC_02311 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02312 7.2e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02313 3.4e-293 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02314 1.8e-153 licT K CAT RNA binding domain
NIDDKIGC_02315 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02316 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02317 1.1e-211 S Bacterial protein of unknown function (DUF871)
NIDDKIGC_02318 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NIDDKIGC_02319 1.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NIDDKIGC_02320 3.6e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_02321 1.2e-134 K UTRA domain
NIDDKIGC_02322 9.9e-154 estA S Putative esterase
NIDDKIGC_02323 7.6e-64
NIDDKIGC_02324 1.2e-201 EGP Major Facilitator Superfamily
NIDDKIGC_02325 4.7e-168 K Transcriptional regulator, LysR family
NIDDKIGC_02326 2.1e-165 G Xylose isomerase-like TIM barrel
NIDDKIGC_02327 1e-156 IQ Enoyl-(Acyl carrier protein) reductase
NIDDKIGC_02328 9.4e-161 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIDDKIGC_02329 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIDDKIGC_02330 1.2e-219 ydiN EGP Major Facilitator Superfamily
NIDDKIGC_02331 9.2e-175 K Transcriptional regulator, LysR family
NIDDKIGC_02332 2.5e-166 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NIDDKIGC_02333 9.3e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NIDDKIGC_02334 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIDDKIGC_02335 0.0 1.3.5.4 C FAD binding domain
NIDDKIGC_02336 2.4e-65 S pyridoxamine 5-phosphate
NIDDKIGC_02337 1.7e-193 C Aldo keto reductase family protein
NIDDKIGC_02338 1.1e-173 galR K Transcriptional regulator
NIDDKIGC_02339 7.7e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NIDDKIGC_02340 0.0 lacS G Transporter
NIDDKIGC_02341 0.0 rafA 3.2.1.22 G alpha-galactosidase
NIDDKIGC_02342 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NIDDKIGC_02343 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NIDDKIGC_02344 2.1e-224 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NIDDKIGC_02345 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NIDDKIGC_02346 3.8e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NIDDKIGC_02347 2e-183 galR K Transcriptional regulator
NIDDKIGC_02348 1.6e-76 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02349 3.5e-111 fic D Fic/DOC family
NIDDKIGC_02350 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
NIDDKIGC_02351 8.6e-232 EGP Major facilitator Superfamily
NIDDKIGC_02352 2.7e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NIDDKIGC_02353 6.8e-229 mdtH P Sugar (and other) transporter
NIDDKIGC_02354 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
NIDDKIGC_02355 1.8e-187 lacR K Transcriptional regulator
NIDDKIGC_02356 0.0 lacA 3.2.1.23 G -beta-galactosidase
NIDDKIGC_02357 0.0 lacS G Transporter
NIDDKIGC_02358 1.3e-249 brnQ U Component of the transport system for branched-chain amino acids
NIDDKIGC_02359 0.0 ubiB S ABC1 family
NIDDKIGC_02360 8.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_02361 2.4e-220 3.1.3.1 S associated with various cellular activities
NIDDKIGC_02362 1.8e-248 S Putative metallopeptidase domain
NIDDKIGC_02363 1.5e-49
NIDDKIGC_02364 5.4e-104 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02365 4.6e-45
NIDDKIGC_02366 2.3e-99 S WxL domain surface cell wall-binding
NIDDKIGC_02367 1.5e-118 S WxL domain surface cell wall-binding
NIDDKIGC_02368 6.1e-164 S Cell surface protein
NIDDKIGC_02369 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
NIDDKIGC_02370 6.5e-262 nox C NADH oxidase
NIDDKIGC_02371 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NIDDKIGC_02372 0.0 pepO 3.4.24.71 O Peptidase family M13
NIDDKIGC_02373 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
NIDDKIGC_02374 1.6e-32 copZ P Heavy-metal-associated domain
NIDDKIGC_02375 1.2e-94 dps P Belongs to the Dps family
NIDDKIGC_02376 1.6e-18
NIDDKIGC_02377 5.6e-40 yrkD S Metal-sensitive transcriptional repressor
NIDDKIGC_02378 9.5e-55 txlA O Thioredoxin-like domain
NIDDKIGC_02379 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NIDDKIGC_02380 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
NIDDKIGC_02381 4.3e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
NIDDKIGC_02382 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
NIDDKIGC_02383 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NIDDKIGC_02384 2.5e-183 yfeX P Peroxidase
NIDDKIGC_02385 6.7e-99 K transcriptional regulator
NIDDKIGC_02386 5.3e-160 4.1.1.46 S Amidohydrolase
NIDDKIGC_02387 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
NIDDKIGC_02388 3e-40
NIDDKIGC_02389 6.8e-53
NIDDKIGC_02390 0.0 L Transposase
NIDDKIGC_02392 4.2e-62
NIDDKIGC_02393 2.5e-53
NIDDKIGC_02394 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
NIDDKIGC_02395 3e-33 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NIDDKIGC_02396 1.5e-227 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
NIDDKIGC_02397 1.8e-27
NIDDKIGC_02398 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NIDDKIGC_02399 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
NIDDKIGC_02400 3.5e-88 K Winged helix DNA-binding domain
NIDDKIGC_02401 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
NIDDKIGC_02402 1.7e-129 S WxL domain surface cell wall-binding
NIDDKIGC_02403 1.5e-186 S Bacterial protein of unknown function (DUF916)
NIDDKIGC_02404 0.0
NIDDKIGC_02405 6e-161 ypuA S Protein of unknown function (DUF1002)
NIDDKIGC_02406 5.5e-50 yvlA
NIDDKIGC_02407 1.2e-95 K transcriptional regulator
NIDDKIGC_02408 3e-90 ymdB S Macro domain protein
NIDDKIGC_02409 1.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NIDDKIGC_02410 2.9e-24 S Protein of unknown function (DUF1093)
NIDDKIGC_02411 2e-77 S Threonine/Serine exporter, ThrE
NIDDKIGC_02412 9.2e-133 thrE S Putative threonine/serine exporter
NIDDKIGC_02413 5.2e-164 yvgN C Aldo keto reductase
NIDDKIGC_02414 3.8e-152 ywkB S Membrane transport protein
NIDDKIGC_02415 5.6e-310 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NIDDKIGC_02416 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
NIDDKIGC_02417 4.5e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
NIDDKIGC_02418 3.8e-76 M1-874 K Domain of unknown function (DUF1836)
NIDDKIGC_02419 6.8e-181 D Alpha beta
NIDDKIGC_02420 7.7e-214 mdtG EGP Major facilitator Superfamily
NIDDKIGC_02421 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
NIDDKIGC_02422 9.4e-65 ycgX S Protein of unknown function (DUF1398)
NIDDKIGC_02423 4.2e-49
NIDDKIGC_02424 3.4e-25
NIDDKIGC_02425 9.7e-248 lmrB EGP Major facilitator Superfamily
NIDDKIGC_02426 7.7e-73 S COG NOG18757 non supervised orthologous group
NIDDKIGC_02427 7.4e-40
NIDDKIGC_02428 9.4e-74 copR K Copper transport repressor CopY TcrY
NIDDKIGC_02429 0.0 copB 3.6.3.4 P P-type ATPase
NIDDKIGC_02430 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NIDDKIGC_02431 1.4e-111 S VIT family
NIDDKIGC_02432 1.8e-119 S membrane
NIDDKIGC_02433 1.6e-158 EG EamA-like transporter family
NIDDKIGC_02434 1.3e-81 elaA S GNAT family
NIDDKIGC_02435 1.1e-115 GM NmrA-like family
NIDDKIGC_02436 2.1e-14
NIDDKIGC_02437 7e-56
NIDDKIGC_02438 1.2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
NIDDKIGC_02439 4.3e-86
NIDDKIGC_02440 1.9e-62
NIDDKIGC_02441 4.1e-214 mutY L A G-specific adenine glycosylase
NIDDKIGC_02442 4e-53
NIDDKIGC_02443 1.7e-66 yeaO S Protein of unknown function, DUF488
NIDDKIGC_02444 7e-71 spx4 1.20.4.1 P ArsC family
NIDDKIGC_02445 9.2e-66 K Winged helix DNA-binding domain
NIDDKIGC_02446 4.8e-162 azoB GM NmrA-like family
NIDDKIGC_02447 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
NIDDKIGC_02448 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_02449 6.8e-251 cycA E Amino acid permease
NIDDKIGC_02450 1.2e-255 nhaC C Na H antiporter NhaC
NIDDKIGC_02451 6.1e-27 3.2.2.10 S Belongs to the LOG family
NIDDKIGC_02452 6.3e-199 frlB M SIS domain
NIDDKIGC_02453 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NIDDKIGC_02454 1.4e-220 S Uncharacterized protein conserved in bacteria (DUF2325)
NIDDKIGC_02455 9.7e-126 yyaQ S YjbR
NIDDKIGC_02457 0.0 cadA P P-type ATPase
NIDDKIGC_02458 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
NIDDKIGC_02459 6.2e-122 E GDSL-like Lipase/Acylhydrolase family
NIDDKIGC_02460 1.4e-77
NIDDKIGC_02461 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
NIDDKIGC_02462 3.3e-97 FG HIT domain
NIDDKIGC_02463 5.9e-174 S Aldo keto reductase
NIDDKIGC_02464 5.1e-53 yitW S Pfam:DUF59
NIDDKIGC_02465 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIDDKIGC_02466 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
NIDDKIGC_02467 3.2e-194 blaA6 V Beta-lactamase
NIDDKIGC_02468 6.2e-96 V VanZ like family
NIDDKIGC_02469 1.5e-42 S COG NOG38524 non supervised orthologous group
NIDDKIGC_02470 7e-40
NIDDKIGC_02472 8.6e-249 EGP Major facilitator Superfamily
NIDDKIGC_02473 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
NIDDKIGC_02474 4.7e-83 cvpA S Colicin V production protein
NIDDKIGC_02475 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NIDDKIGC_02476 1.1e-92 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
NIDDKIGC_02477 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
NIDDKIGC_02478 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NIDDKIGC_02479 2.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
NIDDKIGC_02480 6.1e-213 folP 2.5.1.15 H dihydropteroate synthase
NIDDKIGC_02481 2.5e-95 tag 3.2.2.20 L glycosylase
NIDDKIGC_02482 2.6e-19
NIDDKIGC_02484 7.8e-103 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02485 2.7e-160 czcD P cation diffusion facilitator family transporter
NIDDKIGC_02486 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_02487 3e-116 hly S protein, hemolysin III
NIDDKIGC_02488 1.5e-44 qacH U Small Multidrug Resistance protein
NIDDKIGC_02489 4.4e-59 qacC P Small Multidrug Resistance protein
NIDDKIGC_02490 1.5e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
NIDDKIGC_02491 4e-179 K AI-2E family transporter
NIDDKIGC_02492 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NIDDKIGC_02493 0.0 kup P Transport of potassium into the cell
NIDDKIGC_02495 2.3e-257 yhdG E C-terminus of AA_permease
NIDDKIGC_02496 4.3e-83
NIDDKIGC_02497 6.2e-60 S Protein of unknown function (DUF1211)
NIDDKIGC_02498 1e-140 XK27_06930 S ABC-2 family transporter protein
NIDDKIGC_02499 1.3e-64 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02501 4.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NIDDKIGC_02502 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
NIDDKIGC_02503 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIDDKIGC_02504 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NIDDKIGC_02505 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NIDDKIGC_02506 4.9e-54 S Enterocin A Immunity
NIDDKIGC_02507 3.6e-257 gor 1.8.1.7 C Glutathione reductase
NIDDKIGC_02508 8.3e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NIDDKIGC_02509 1.1e-183 D Alpha beta
NIDDKIGC_02510 5.3e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
NIDDKIGC_02511 1.6e-293 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
NIDDKIGC_02512 3.5e-118 yugP S Putative neutral zinc metallopeptidase
NIDDKIGC_02513 4.1e-25
NIDDKIGC_02514 2.5e-145 DegV S EDD domain protein, DegV family
NIDDKIGC_02515 7.3e-127 lrgB M LrgB-like family
NIDDKIGC_02516 5.1e-64 lrgA S LrgA family
NIDDKIGC_02517 3.8e-104 J Acetyltransferase (GNAT) domain
NIDDKIGC_02518 6.9e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
NIDDKIGC_02519 1.3e-34 S Phospholipase_D-nuclease N-terminal
NIDDKIGC_02520 2.1e-58 S Enterocin A Immunity
NIDDKIGC_02521 9.8e-88 perR P Belongs to the Fur family
NIDDKIGC_02522 2.5e-104
NIDDKIGC_02523 7.9e-238 S module of peptide synthetase
NIDDKIGC_02524 2e-100 S NADPH-dependent FMN reductase
NIDDKIGC_02525 1.4e-08
NIDDKIGC_02526 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
NIDDKIGC_02527 1.5e-303 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02528 3e-37 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02529 1.3e-154 1.6.5.2 GM NmrA-like family
NIDDKIGC_02530 2e-77 merR K MerR family regulatory protein
NIDDKIGC_02531 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIDDKIGC_02532 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NIDDKIGC_02533 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_02534 6.3e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
NIDDKIGC_02535 2e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
NIDDKIGC_02536 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NIDDKIGC_02537 1.7e-148 cof S haloacid dehalogenase-like hydrolase
NIDDKIGC_02538 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
NIDDKIGC_02539 9.4e-77
NIDDKIGC_02540 2.1e-274 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NIDDKIGC_02541 6.1e-117 ybbL S ABC transporter, ATP-binding protein
NIDDKIGC_02542 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
NIDDKIGC_02543 2.6e-205 S DUF218 domain
NIDDKIGC_02544 3.7e-182 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
NIDDKIGC_02545 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
NIDDKIGC_02546 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02547 5e-128 S Putative adhesin
NIDDKIGC_02548 5.1e-84 XK27_06920 S Protein of unknown function (DUF1700)
NIDDKIGC_02549 6.8e-53 K Transcriptional regulator
NIDDKIGC_02550 2.9e-78 KT response to antibiotic
NIDDKIGC_02551 1.5e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NIDDKIGC_02552 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NIDDKIGC_02553 2.4e-122 tcyB E ABC transporter
NIDDKIGC_02554 6.8e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NIDDKIGC_02555 3e-234 EK Aminotransferase, class I
NIDDKIGC_02556 6.1e-168 K LysR substrate binding domain
NIDDKIGC_02557 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_02558 0.0 S Bacterial membrane protein YfhO
NIDDKIGC_02559 4.1e-226 nupG F Nucleoside
NIDDKIGC_02560 2.7e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NIDDKIGC_02561 2.7e-149 noc K Belongs to the ParB family
NIDDKIGC_02562 1.8e-136 soj D Sporulation initiation inhibitor
NIDDKIGC_02563 4.8e-157 spo0J K Belongs to the ParB family
NIDDKIGC_02564 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
NIDDKIGC_02565 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NIDDKIGC_02566 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
NIDDKIGC_02567 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NIDDKIGC_02568 1.7e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NIDDKIGC_02569 5.5e-124 yoaK S Protein of unknown function (DUF1275)
NIDDKIGC_02570 3.2e-124 K response regulator
NIDDKIGC_02571 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
NIDDKIGC_02572 7.1e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NIDDKIGC_02573 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
NIDDKIGC_02574 5.1e-131 azlC E branched-chain amino acid
NIDDKIGC_02575 2.3e-54 azlD S branched-chain amino acid
NIDDKIGC_02576 8e-110 S membrane transporter protein
NIDDKIGC_02577 4.1e-54
NIDDKIGC_02579 4.3e-74 S Psort location Cytoplasmic, score
NIDDKIGC_02580 1.7e-96 S Domain of unknown function (DUF4352)
NIDDKIGC_02581 2.9e-23 S Protein of unknown function (DUF4064)
NIDDKIGC_02582 5e-201 KLT Protein tyrosine kinase
NIDDKIGC_02583 3.6e-163
NIDDKIGC_02584 9.5e-233 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NIDDKIGC_02585 2.4e-83
NIDDKIGC_02586 1.7e-210 xylR GK ROK family
NIDDKIGC_02587 4.9e-172 K AI-2E family transporter
NIDDKIGC_02588 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIDDKIGC_02589 2.3e-120 Q Methyltransferase domain
NIDDKIGC_02590 4.4e-39
NIDDKIGC_02591 2.3e-64 yobT S PFAM Metallo-beta-lactamase superfamily
NIDDKIGC_02592 8.1e-12 S Domain of unknown function (DUF4260)
NIDDKIGC_02593 2.2e-109 XK27_06930 S ABC-2 family transporter protein
NIDDKIGC_02594 1.3e-36 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02595 5.4e-53 ydeA S intracellular protease amidase
NIDDKIGC_02596 0.0 L Transposase
NIDDKIGC_02597 4.3e-155 L Integrase core domain
NIDDKIGC_02598 9.8e-39 L Transposase and inactivated derivatives
NIDDKIGC_02599 6.8e-72 dptF L COG0433 Predicted ATPase
NIDDKIGC_02600 1.9e-56 dptG
NIDDKIGC_02601 3.1e-259 S Domain of unknown function DUF87
NIDDKIGC_02602 2.1e-198 S Membrane
NIDDKIGC_02603 3e-43 L Transposase and inactivated derivatives, IS30 family
NIDDKIGC_02605 4.3e-13 S Mor transcription activator family
NIDDKIGC_02606 2.1e-16
NIDDKIGC_02607 5.9e-23 S Mor transcription activator family
NIDDKIGC_02608 2.3e-29
NIDDKIGC_02609 1.6e-10 S Mor transcription activator family
NIDDKIGC_02610 1.3e-76
NIDDKIGC_02611 8.5e-37
NIDDKIGC_02613 3.5e-37 3.1.3.16 S Protein of unknown function (DUF1643)
NIDDKIGC_02614 1.3e-135 L Phage integrase SAM-like domain
NIDDKIGC_02615 1.2e-25 2.7.7.49 L Reverse transcriptase (RNA-dependent DNA polymerase)
NIDDKIGC_02617 1.2e-32 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NIDDKIGC_02618 8.8e-40
NIDDKIGC_02620 6.8e-33 L transposase activity
NIDDKIGC_02622 2.4e-104 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02623 9.2e-65 S Domain of unknown function (DUF4440)
NIDDKIGC_02624 3.6e-258 qacA EGP Fungal trichothecene efflux pump (TRI12)
NIDDKIGC_02625 2.7e-76 3.5.4.1 GM SnoaL-like domain
NIDDKIGC_02626 3.7e-108 GM NAD(P)H-binding
NIDDKIGC_02627 4.6e-112 akr5f 1.1.1.346 S reductase
NIDDKIGC_02628 4.6e-104 M ErfK YbiS YcfS YnhG
NIDDKIGC_02629 4.3e-99 acmD 3.2.1.17 NU Bacterial SH3 domain
NIDDKIGC_02630 5.8e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NIDDKIGC_02631 1.5e-50 K Helix-turn-helix domain
NIDDKIGC_02632 1e-64 V ABC transporter
NIDDKIGC_02633 3.3e-66
NIDDKIGC_02634 2.2e-41 K HxlR-like helix-turn-helix
NIDDKIGC_02635 1e-107 ydeA S intracellular protease amidase
NIDDKIGC_02636 1.1e-43 S Protein of unknown function (DUF3781)
NIDDKIGC_02637 1.5e-207 S Membrane
NIDDKIGC_02638 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NIDDKIGC_02639 1.4e-47 ulaB 2.7.1.194, 2.7.1.200 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NIDDKIGC_02640 4.9e-233 ulaA 2.7.1.194 S PTS system sugar-specific permease component
NIDDKIGC_02641 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NIDDKIGC_02642 2.6e-64 S Protein of unknown function (DUF1093)
NIDDKIGC_02643 0.0 bglF 2.7.1.193, 2.7.1.211 G phosphotransferase system
NIDDKIGC_02644 3.8e-292 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02645 8e-146 licT2 K CAT RNA binding domain
NIDDKIGC_02647 1.9e-30
NIDDKIGC_02648 1.7e-84 dps P Belongs to the Dps family
NIDDKIGC_02649 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
NIDDKIGC_02650 4.4e-280 1.3.5.4 C FAD binding domain
NIDDKIGC_02651 3e-162 K LysR substrate binding domain
NIDDKIGC_02652 9.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
NIDDKIGC_02653 3.9e-290 yjcE P Sodium proton antiporter
NIDDKIGC_02654 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NIDDKIGC_02655 4e-116 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02656 3.8e-179 NU Mycoplasma protein of unknown function, DUF285
NIDDKIGC_02657 9.6e-90 S WxL domain surface cell wall-binding
NIDDKIGC_02658 1.2e-175 S Bacterial protein of unknown function (DUF916)
NIDDKIGC_02659 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
NIDDKIGC_02660 2.1e-64 K helix_turn_helix, mercury resistance
NIDDKIGC_02661 7.5e-152 IQ Enoyl-(Acyl carrier protein) reductase
NIDDKIGC_02662 1.3e-68 maa S transferase hexapeptide repeat
NIDDKIGC_02663 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_02664 4.1e-164 GM NmrA-like family
NIDDKIGC_02665 5.4e-92 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02666 8.6e-171 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIDDKIGC_02667 9.5e-178 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NIDDKIGC_02668 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
NIDDKIGC_02669 5.2e-170 fhuD P Periplasmic binding protein
NIDDKIGC_02670 4.3e-109 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02671 2.3e-252 yfjF U Sugar (and other) transporter
NIDDKIGC_02672 1.5e-180 S Aldo keto reductase
NIDDKIGC_02673 7e-101 S Protein of unknown function (DUF1211)
NIDDKIGC_02674 1.2e-191 1.1.1.219 GM Male sterility protein
NIDDKIGC_02675 3.2e-98 K Bacterial regulatory proteins, tetR family
NIDDKIGC_02676 9.8e-132 ydfG S KR domain
NIDDKIGC_02677 3.7e-63 hxlR K HxlR-like helix-turn-helix
NIDDKIGC_02678 2.9e-47 S Domain of unknown function (DUF1905)
NIDDKIGC_02679 0.0 M Glycosyl hydrolases family 25
NIDDKIGC_02680 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NIDDKIGC_02681 2.4e-167 GM NmrA-like family
NIDDKIGC_02682 1.4e-99 fadR K Bacterial regulatory proteins, tetR family
NIDDKIGC_02683 3e-205 2.7.13.3 T GHKL domain
NIDDKIGC_02684 8.2e-134 K LytTr DNA-binding domain
NIDDKIGC_02685 0.0 asnB 6.3.5.4 E Asparagine synthase
NIDDKIGC_02686 1.4e-94 M ErfK YbiS YcfS YnhG
NIDDKIGC_02687 4.9e-213 ytbD EGP Major facilitator Superfamily
NIDDKIGC_02688 2e-61 K Transcriptional regulator, HxlR family
NIDDKIGC_02689 3e-116 S Haloacid dehalogenase-like hydrolase
NIDDKIGC_02690 5.9e-117
NIDDKIGC_02691 1.2e-214 NU Mycoplasma protein of unknown function, DUF285
NIDDKIGC_02692 1.1e-62
NIDDKIGC_02693 7.5e-101 S WxL domain surface cell wall-binding
NIDDKIGC_02694 4.7e-188 S Cell surface protein
NIDDKIGC_02695 2.5e-115 S GyrI-like small molecule binding domain
NIDDKIGC_02696 3.8e-69 S Iron-sulphur cluster biosynthesis
NIDDKIGC_02697 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
NIDDKIGC_02698 1.7e-101 S WxL domain surface cell wall-binding
NIDDKIGC_02699 9.2e-187 S Cell surface protein
NIDDKIGC_02700 1.3e-75
NIDDKIGC_02701 1.4e-262
NIDDKIGC_02702 3.5e-228 hpk9 2.7.13.3 T GHKL domain
NIDDKIGC_02703 2.9e-38 S TfoX C-terminal domain
NIDDKIGC_02704 5.1e-139 K Helix-turn-helix domain
NIDDKIGC_02705 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NIDDKIGC_02706 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIDDKIGC_02707 2.7e-42 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NIDDKIGC_02708 0.0 ctpA 3.6.3.54 P P-type ATPase
NIDDKIGC_02709 2.3e-212 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
NIDDKIGC_02710 1.1e-155 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NIDDKIGC_02711 3.9e-40 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
NIDDKIGC_02712 3.9e-66 lysM M LysM domain
NIDDKIGC_02713 6.2e-266 yjeM E Amino Acid
NIDDKIGC_02714 2.5e-144 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02715 1.1e-69
NIDDKIGC_02717 7.7e-163 IQ KR domain
NIDDKIGC_02718 4.3e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
NIDDKIGC_02719 3.5e-42
NIDDKIGC_02720 1.1e-309 XK27_09600 V ABC transporter, ATP-binding protein
NIDDKIGC_02721 0.0 V ABC transporter
NIDDKIGC_02722 8.6e-218 ykiI
NIDDKIGC_02723 1.2e-115 GM NAD(P)H-binding
NIDDKIGC_02724 1.9e-138 IQ reductase
NIDDKIGC_02725 3.7e-60 I sulfurtransferase activity
NIDDKIGC_02726 2.3e-77 yphH S Cupin domain
NIDDKIGC_02727 4.7e-93 S Phosphatidylethanolamine-binding protein
NIDDKIGC_02728 1.6e-117 GM NAD(P)H-binding
NIDDKIGC_02729 7.4e-176 C C4-dicarboxylate transmembrane transporter activity
NIDDKIGC_02730 3.8e-131 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_02731 1.3e-72
NIDDKIGC_02732 3.4e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
NIDDKIGC_02733 4.7e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
NIDDKIGC_02734 9.3e-74 S Psort location Cytoplasmic, score
NIDDKIGC_02735 8.8e-220 T diguanylate cyclase
NIDDKIGC_02736 1.5e-120 tag 3.2.2.20 L Methyladenine glycosylase
NIDDKIGC_02737 4.2e-92
NIDDKIGC_02738 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
NIDDKIGC_02739 1.8e-54 nudA S ASCH
NIDDKIGC_02740 4.7e-108 S SdpI/YhfL protein family
NIDDKIGC_02741 6.1e-34 M Lysin motif
NIDDKIGC_02742 2.5e-42 M Lysin motif
NIDDKIGC_02743 2.3e-65 M LysM domain
NIDDKIGC_02744 5.1e-75 K helix_turn_helix, mercury resistance
NIDDKIGC_02745 4.4e-186 1.1.1.219 GM Male sterility protein
NIDDKIGC_02746 8.3e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02747 2.7e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NIDDKIGC_02748 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_02749 3.4e-74 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIDDKIGC_02750 1.9e-33 L Transposase
NIDDKIGC_02751 5.2e-273 L Transposase
NIDDKIGC_02752 5.3e-150 dicA K Helix-turn-helix domain
NIDDKIGC_02753 3.2e-55
NIDDKIGC_02754 3.4e-160 T Calcineurin-like phosphoesterase superfamily domain
NIDDKIGC_02755 8.2e-63
NIDDKIGC_02756 0.0 P Concanavalin A-like lectin/glucanases superfamily
NIDDKIGC_02757 0.0 yhcA V ABC transporter, ATP-binding protein
NIDDKIGC_02758 1.2e-95 cadD P Cadmium resistance transporter
NIDDKIGC_02759 2e-49 K Transcriptional regulator, ArsR family
NIDDKIGC_02760 1.9e-116 S SNARE associated Golgi protein
NIDDKIGC_02761 1.1e-46
NIDDKIGC_02762 6.8e-72 T Belongs to the universal stress protein A family
NIDDKIGC_02763 2.1e-283 mntH P H( )-stimulated, divalent metal cation uptake system
NIDDKIGC_02764 1.6e-122 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02765 2.8e-82 gtrA S GtrA-like protein
NIDDKIGC_02766 3.5e-114 zmp3 O Zinc-dependent metalloprotease
NIDDKIGC_02767 7e-33
NIDDKIGC_02769 6e-211 livJ E Receptor family ligand binding region
NIDDKIGC_02770 6.5e-154 livH U Branched-chain amino acid transport system / permease component
NIDDKIGC_02771 5.3e-141 livM E Branched-chain amino acid transport system / permease component
NIDDKIGC_02772 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
NIDDKIGC_02773 3.3e-124 livF E ABC transporter
NIDDKIGC_02774 2.4e-97 acuB S Domain in cystathionine beta-synthase and other proteins.
NIDDKIGC_02775 1e-91 S WxL domain surface cell wall-binding
NIDDKIGC_02776 7.3e-189 S Cell surface protein
NIDDKIGC_02777 8.6e-63
NIDDKIGC_02778 4.7e-261
NIDDKIGC_02779 3.5e-169 XK27_00670 S ABC transporter
NIDDKIGC_02780 4.8e-153 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
NIDDKIGC_02781 9e-119 cmpC S ATPases associated with a variety of cellular activities
NIDDKIGC_02782 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
NIDDKIGC_02783 1.3e-119 drgA C Nitroreductase family
NIDDKIGC_02784 1.1e-95 rmaB K Transcriptional regulator, MarR family
NIDDKIGC_02785 0.0 lmrA 3.6.3.44 V ABC transporter
NIDDKIGC_02786 1.7e-162 ypbG 2.7.1.2 GK ROK family
NIDDKIGC_02787 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
NIDDKIGC_02788 2.1e-111 K Transcriptional regulator C-terminal region
NIDDKIGC_02789 3e-178 4.1.1.52 S Amidohydrolase
NIDDKIGC_02790 4.4e-129 E lipolytic protein G-D-S-L family
NIDDKIGC_02791 4e-159 yicL EG EamA-like transporter family
NIDDKIGC_02792 3e-225 sdrF M Collagen binding domain
NIDDKIGC_02793 5.1e-270 I acetylesterase activity
NIDDKIGC_02794 5.2e-177 S Phosphotransferase system, EIIC
NIDDKIGC_02795 1.8e-133 aroD S Alpha/beta hydrolase family
NIDDKIGC_02796 3.2e-37
NIDDKIGC_02798 2.6e-135 S zinc-ribbon domain
NIDDKIGC_02799 4.8e-263 S response to antibiotic
NIDDKIGC_02800 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
NIDDKIGC_02801 2.4e-243 P Sodium:sulfate symporter transmembrane region
NIDDKIGC_02802 2.2e-165 K LysR substrate binding domain
NIDDKIGC_02803 4.4e-79
NIDDKIGC_02804 4.9e-22
NIDDKIGC_02805 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NIDDKIGC_02806 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NIDDKIGC_02807 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NIDDKIGC_02808 2.8e-79
NIDDKIGC_02809 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NIDDKIGC_02810 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NIDDKIGC_02811 3.1e-127 yliE T EAL domain
NIDDKIGC_02812 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
NIDDKIGC_02813 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NIDDKIGC_02814 5.6e-39 S Cytochrome B5
NIDDKIGC_02815 1.6e-237
NIDDKIGC_02816 4.8e-131 treR K UTRA
NIDDKIGC_02817 2e-160 I alpha/beta hydrolase fold
NIDDKIGC_02818 1.7e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
NIDDKIGC_02819 2.2e-233 yxiO S Vacuole effluxer Atg22 like
NIDDKIGC_02820 3.7e-249 puuP_1 E Amino acid permease
NIDDKIGC_02821 4.7e-176 pepR1 3.4.11.5 I Releases the N-terminal proline from various substrates
NIDDKIGC_02822 7.6e-174 ropB K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02823 4.4e-209 EGP Major facilitator Superfamily
NIDDKIGC_02824 0.0 uvrA3 L excinuclease ABC
NIDDKIGC_02825 0.0 S Predicted membrane protein (DUF2207)
NIDDKIGC_02826 5.3e-147 3.1.3.102, 3.1.3.104 S hydrolase
NIDDKIGC_02827 3.2e-308 ybiT S ABC transporter, ATP-binding protein
NIDDKIGC_02828 4.5e-222 S CAAX protease self-immunity
NIDDKIGC_02829 1e-132 2.7.1.89 M Phosphotransferase enzyme family
NIDDKIGC_02830 1.1e-95 2.3.1.128 J Acetyltransferase (GNAT) domain
NIDDKIGC_02831 3.2e-103 speG J Acetyltransferase (GNAT) domain
NIDDKIGC_02832 6.3e-139 endA F DNA RNA non-specific endonuclease
NIDDKIGC_02833 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
NIDDKIGC_02834 3.4e-109 K Transcriptional regulator (TetR family)
NIDDKIGC_02835 1.6e-261 yhgE V domain protein
NIDDKIGC_02836 6.1e-09
NIDDKIGC_02838 4.8e-244 EGP Major facilitator Superfamily
NIDDKIGC_02839 0.0 mdlA V ABC transporter
NIDDKIGC_02840 0.0 mdlB V ABC transporter
NIDDKIGC_02842 2.4e-192 C Aldo/keto reductase family
NIDDKIGC_02843 1.9e-102 M Protein of unknown function (DUF3737)
NIDDKIGC_02844 1.4e-220 patB 4.4.1.8 E Aminotransferase, class I
NIDDKIGC_02845 1e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NIDDKIGC_02846 1.7e-62
NIDDKIGC_02847 2.4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIDDKIGC_02848 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
NIDDKIGC_02849 6.1e-76 T Belongs to the universal stress protein A family
NIDDKIGC_02850 3.4e-35
NIDDKIGC_02851 1.7e-93 Z012_04635 K Helix-turn-helix XRE-family like proteins
NIDDKIGC_02852 1.5e-76 EGP Major facilitator Superfamily
NIDDKIGC_02853 9.3e-24 EGP Major facilitator Superfamily
NIDDKIGC_02854 5.7e-83 GM NAD(P)H-binding
NIDDKIGC_02855 2.1e-140 EGP Major Facilitator Superfamily
NIDDKIGC_02856 2e-139 akr5f 1.1.1.346 S reductase
NIDDKIGC_02857 3.9e-132 C Aldo keto reductase
NIDDKIGC_02858 2.2e-115 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_02859 2.8e-20 adhR K helix_turn_helix, mercury resistance
NIDDKIGC_02860 1.8e-25 fldA C Flavodoxin
NIDDKIGC_02862 2e-78 K Transcriptional regulator
NIDDKIGC_02863 8.3e-109 akr5f 1.1.1.346 S reductase
NIDDKIGC_02864 1.6e-85 GM NAD(P)H-binding
NIDDKIGC_02865 7.3e-94 glcU U sugar transport
NIDDKIGC_02866 2.3e-126 IQ reductase
NIDDKIGC_02867 8e-75 darA C Flavodoxin
NIDDKIGC_02868 6.7e-83 yiiE S Protein of unknown function (DUF1211)
NIDDKIGC_02869 4.7e-141 aRA11 1.1.1.346 S reductase
NIDDKIGC_02870 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
NIDDKIGC_02871 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NIDDKIGC_02872 1e-102 GM NAD(P)H-binding
NIDDKIGC_02873 2.8e-157 K LysR substrate binding domain
NIDDKIGC_02874 9.5e-68 S Domain of unknown function (DUF4440)
NIDDKIGC_02875 4.4e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
NIDDKIGC_02876 2.4e-47
NIDDKIGC_02877 3.2e-37
NIDDKIGC_02878 2.5e-86 yvbK 3.1.3.25 K GNAT family
NIDDKIGC_02879 1.3e-84
NIDDKIGC_02880 2.2e-111 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIDDKIGC_02881 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NIDDKIGC_02882 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIDDKIGC_02883 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NIDDKIGC_02885 1.3e-120 macB V ABC transporter, ATP-binding protein
NIDDKIGC_02886 0.0 ylbB V ABC transporter permease
NIDDKIGC_02887 3e-237 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NIDDKIGC_02888 4.4e-79 K transcriptional regulator, MerR family
NIDDKIGC_02889 3.2e-76 yphH S Cupin domain
NIDDKIGC_02890 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
NIDDKIGC_02891 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NIDDKIGC_02892 4.7e-211 natB CP ABC-2 family transporter protein
NIDDKIGC_02893 3.6e-168 natA S ABC transporter, ATP-binding protein
NIDDKIGC_02894 1.8e-92 ogt 2.1.1.63 L Methyltransferase
NIDDKIGC_02895 4.5e-45 lytE M LysM domain
NIDDKIGC_02897 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
NIDDKIGC_02898 1e-295 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
NIDDKIGC_02899 3.7e-151 rlrG K Transcriptional regulator
NIDDKIGC_02900 9.3e-173 S Conserved hypothetical protein 698
NIDDKIGC_02901 3.4e-100 rimL J Acetyltransferase (GNAT) domain
NIDDKIGC_02902 2e-75 S Domain of unknown function (DUF4811)
NIDDKIGC_02903 2.4e-270 lmrB EGP Major facilitator Superfamily
NIDDKIGC_02904 1.3e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NIDDKIGC_02905 3.3e-60 ynfM EGP Major facilitator Superfamily
NIDDKIGC_02906 6.6e-123 ynfM EGP Major facilitator Superfamily
NIDDKIGC_02907 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
NIDDKIGC_02908 1.2e-155 mleP3 S Membrane transport protein
NIDDKIGC_02909 1.6e-85 S Membrane
NIDDKIGC_02910 9.1e-188 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NIDDKIGC_02911 3.1e-98 1.5.1.3 H RibD C-terminal domain
NIDDKIGC_02912 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
NIDDKIGC_02913 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
NIDDKIGC_02914 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NIDDKIGC_02915 5.2e-174 hrtB V ABC transporter permease
NIDDKIGC_02916 6.6e-95 S Protein of unknown function (DUF1440)
NIDDKIGC_02917 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NIDDKIGC_02918 9.8e-39 KT helix_turn_helix, mercury resistance
NIDDKIGC_02919 2.3e-99 KT helix_turn_helix, mercury resistance
NIDDKIGC_02920 1.6e-115 S Protein of unknown function (DUF554)
NIDDKIGC_02921 1.1e-92 yueI S Protein of unknown function (DUF1694)
NIDDKIGC_02922 2e-143 yvpB S Peptidase_C39 like family
NIDDKIGC_02923 4.2e-149 M Glycosyl hydrolases family 25
NIDDKIGC_02924 3.9e-111
NIDDKIGC_02925 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NIDDKIGC_02926 1.8e-84 hmpT S Pfam:DUF3816
NIDDKIGC_02927 1.5e-42 S COG NOG38524 non supervised orthologous group
NIDDKIGC_02929 4.6e-163 K Transcriptional regulator
NIDDKIGC_02930 5.7e-163 akr5f 1.1.1.346 S reductase
NIDDKIGC_02931 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
NIDDKIGC_02932 7.9e-79 K Winged helix DNA-binding domain
NIDDKIGC_02933 1.1e-267 ycaM E amino acid
NIDDKIGC_02934 3e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
NIDDKIGC_02935 2.7e-32
NIDDKIGC_02936 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
NIDDKIGC_02937 0.0 M Bacterial Ig-like domain (group 3)
NIDDKIGC_02938 1.9e-77 fld C Flavodoxin
NIDDKIGC_02939 1.9e-231
NIDDKIGC_02940 2.1e-88 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
NIDDKIGC_02941 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
NIDDKIGC_02942 8.3e-152 EG EamA-like transporter family
NIDDKIGC_02943 6.5e-182 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NIDDKIGC_02944 9.8e-152 S hydrolase
NIDDKIGC_02945 1.8e-81
NIDDKIGC_02946 4.2e-121 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NIDDKIGC_02947 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
NIDDKIGC_02948 1.8e-130 gntR K UTRA
NIDDKIGC_02949 5e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NIDDKIGC_02950 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NIDDKIGC_02951 8.6e-297 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02952 6.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NIDDKIGC_02953 1.2e-244 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NIDDKIGC_02954 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
NIDDKIGC_02955 3.2e-154 V ABC transporter
NIDDKIGC_02956 1.3e-117 K Transcriptional regulator
NIDDKIGC_02957 1.5e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NIDDKIGC_02958 3.6e-88 niaR S 3H domain
NIDDKIGC_02959 4.7e-225 EGP Major facilitator Superfamily
NIDDKIGC_02960 2.1e-232 S Sterol carrier protein domain
NIDDKIGC_02961 1.9e-211 S Bacterial protein of unknown function (DUF871)
NIDDKIGC_02962 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
NIDDKIGC_02963 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
NIDDKIGC_02964 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
NIDDKIGC_02965 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
NIDDKIGC_02966 1.9e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
NIDDKIGC_02967 1.5e-11 mcbG S Pentapeptide repeats (8 copies)
NIDDKIGC_02968 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
NIDDKIGC_02969 3.6e-282 thrC 4.2.3.1 E Threonine synthase
NIDDKIGC_02970 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NIDDKIGC_02972 1.5e-52
NIDDKIGC_02973 5.4e-118
NIDDKIGC_02974 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
NIDDKIGC_02975 3.9e-234 malY 4.4.1.8 E Aminotransferase, class I
NIDDKIGC_02977 2.7e-49
NIDDKIGC_02978 4.3e-88
NIDDKIGC_02979 2.1e-70 gtcA S Teichoic acid glycosylation protein
NIDDKIGC_02980 1.2e-35
NIDDKIGC_02981 6.7e-81 uspA T universal stress protein
NIDDKIGC_02982 5.8e-149
NIDDKIGC_02983 6.9e-164 V ABC transporter, ATP-binding protein
NIDDKIGC_02984 7.9e-61 gntR1 K Transcriptional regulator, GntR family
NIDDKIGC_02985 8e-42
NIDDKIGC_02986 0.0 V FtsX-like permease family
NIDDKIGC_02987 1.7e-139 cysA V ABC transporter, ATP-binding protein
NIDDKIGC_02988 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
NIDDKIGC_02989 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
NIDDKIGC_02990 9.2e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
NIDDKIGC_02991 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
NIDDKIGC_02992 8.4e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
NIDDKIGC_02993 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
NIDDKIGC_02994 1.5e-223 XK27_09615 1.3.5.4 S reductase
NIDDKIGC_02995 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NIDDKIGC_02996 7.4e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NIDDKIGC_02997 1.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NIDDKIGC_02998 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIDDKIGC_02999 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIDDKIGC_03000 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NIDDKIGC_03001 4.3e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NIDDKIGC_03002 5.2e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NIDDKIGC_03003 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NIDDKIGC_03004 6.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NIDDKIGC_03005 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
NIDDKIGC_03006 5.9e-123 2.1.1.14 E Methionine synthase
NIDDKIGC_03007 3.9e-251 pgaC GT2 M Glycosyl transferase
NIDDKIGC_03008 4.4e-94
NIDDKIGC_03009 6.5e-156 T EAL domain
NIDDKIGC_03010 3.9e-162 GM NmrA-like family
NIDDKIGC_03011 2.4e-221 pbuG S Permease family
NIDDKIGC_03012 2.7e-236 pbuX F xanthine permease
NIDDKIGC_03013 1e-298 pucR QT Purine catabolism regulatory protein-like family
NIDDKIGC_03014 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NIDDKIGC_03015 7.3e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NIDDKIGC_03016 7.6e-244 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NIDDKIGC_03017 1.5e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NIDDKIGC_03018 1.3e-92 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIDDKIGC_03019 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NIDDKIGC_03020 7.4e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NIDDKIGC_03021 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NIDDKIGC_03022 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NIDDKIGC_03023 1.3e-171 ydcZ S Putative inner membrane exporter, YdcZ
NIDDKIGC_03024 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NIDDKIGC_03025 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NIDDKIGC_03026 8.2e-96 wecD K Acetyltransferase (GNAT) family
NIDDKIGC_03027 5.6e-115 ylbE GM NAD(P)H-binding
NIDDKIGC_03028 1.9e-161 mleR K LysR family
NIDDKIGC_03029 1.7e-126 S membrane transporter protein
NIDDKIGC_03030 3e-18
NIDDKIGC_03031 1.1e-158 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NIDDKIGC_03032 1.4e-217 patA 2.6.1.1 E Aminotransferase
NIDDKIGC_03033 5.5e-261 gabR K Bacterial regulatory proteins, gntR family
NIDDKIGC_03034 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NIDDKIGC_03035 8.5e-57 S SdpI/YhfL protein family
NIDDKIGC_03036 1.8e-173 C Zinc-binding dehydrogenase
NIDDKIGC_03037 1.2e-61 K helix_turn_helix, mercury resistance
NIDDKIGC_03038 1.1e-212 yttB EGP Major facilitator Superfamily
NIDDKIGC_03039 2.6e-270 yjcE P Sodium proton antiporter
NIDDKIGC_03040 4.9e-87 nrdI F Belongs to the NrdI family
NIDDKIGC_03041 1.8e-240 yhdP S Transporter associated domain
NIDDKIGC_03042 4.4e-58
NIDDKIGC_03043 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
NIDDKIGC_03044 4.5e-61
NIDDKIGC_03045 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
NIDDKIGC_03046 5.5e-138 rrp8 K LytTr DNA-binding domain
NIDDKIGC_03047 5e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NIDDKIGC_03048 5.2e-139
NIDDKIGC_03049 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NIDDKIGC_03050 2.4e-130 gntR2 K Transcriptional regulator
NIDDKIGC_03051 1.1e-166 S Putative esterase
NIDDKIGC_03052 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NIDDKIGC_03053 9.4e-225 lsgC M Glycosyl transferases group 1
NIDDKIGC_03054 5.6e-21 S Protein of unknown function (DUF2929)
NIDDKIGC_03055 1.7e-48 K Cro/C1-type HTH DNA-binding domain
NIDDKIGC_03056 3.7e-69 S response to antibiotic
NIDDKIGC_03057 4.2e-44 S zinc-ribbon domain
NIDDKIGC_03058 5.7e-20
NIDDKIGC_03059 8.7e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NIDDKIGC_03060 3e-78 uspA T universal stress protein
NIDDKIGC_03061 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
NIDDKIGC_03062 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
NIDDKIGC_03063 4e-60
NIDDKIGC_03064 1.7e-73
NIDDKIGC_03065 5e-82 yybC S Protein of unknown function (DUF2798)
NIDDKIGC_03066 6.3e-45
NIDDKIGC_03067 5.2e-47
NIDDKIGC_03068 9.3e-206 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
NIDDKIGC_03069 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
NIDDKIGC_03070 8.4e-145 yjfP S Dienelactone hydrolase family
NIDDKIGC_03071 9.8e-28
NIDDKIGC_03072 3.9e-76 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_03073 2.8e-140 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_03074 4.8e-26 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NIDDKIGC_03077 6.9e-10
NIDDKIGC_03078 3.8e-09
NIDDKIGC_03080 1.2e-192 L Psort location Cytoplasmic, score
NIDDKIGC_03081 8.2e-34
NIDDKIGC_03082 1.5e-286 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NIDDKIGC_03083 0.0 L MobA MobL family protein
NIDDKIGC_03084 2.5e-27
NIDDKIGC_03085 8.9e-41
NIDDKIGC_03086 8.3e-117 S protein conserved in bacteria
NIDDKIGC_03087 5.9e-28
NIDDKIGC_03088 9.6e-43 relB L Addiction module antitoxin, RelB DinJ family
NIDDKIGC_03089 1.6e-170 repA S Replication initiator protein A
NIDDKIGC_03090 2.9e-35
NIDDKIGC_03091 4e-150 D CobQ CobB MinD ParA nucleotide binding domain protein
NIDDKIGC_03092 2.4e-104 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NIDDKIGC_03094 2.6e-54 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
NIDDKIGC_03095 2.3e-139 L Integrase core domain
NIDDKIGC_03096 2.2e-33 L Transposase
NIDDKIGC_03097 0.0 cadA P P-type ATPase
NIDDKIGC_03098 1.9e-167 L Psort location Cytoplasmic, score
NIDDKIGC_03099 1.7e-18
NIDDKIGC_03100 1.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NIDDKIGC_03101 1.1e-56 arsD S Arsenical resistance operon trans-acting repressor ArsD
NIDDKIGC_03102 2.1e-233 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NIDDKIGC_03103 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
NIDDKIGC_03104 2.7e-57 arsR K Helix-turn-helix domain
NIDDKIGC_03105 9.5e-61 L Domain of unknown function (DUF4158)
NIDDKIGC_03106 8.1e-151 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NIDDKIGC_03107 4.5e-263 npr 1.11.1.1 C NADH oxidase
NIDDKIGC_03108 4.1e-68 S pyridoxamine 5-phosphate
NIDDKIGC_03109 1e-52 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NIDDKIGC_03110 1.3e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
NIDDKIGC_03112 4.5e-11
NIDDKIGC_03113 6.9e-10
NIDDKIGC_03114 1.4e-41
NIDDKIGC_03115 1.2e-192 L Psort location Cytoplasmic, score
NIDDKIGC_03116 8.2e-34
NIDDKIGC_03117 1.5e-286 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NIDDKIGC_03118 0.0 L MobA MobL family protein
NIDDKIGC_03119 2.5e-27
NIDDKIGC_03120 8.9e-41
NIDDKIGC_03121 8.3e-117 S protein conserved in bacteria
NIDDKIGC_03122 5.9e-28
NIDDKIGC_03123 9.6e-43 relB L Addiction module antitoxin, RelB DinJ family
NIDDKIGC_03124 1.6e-170 repA S Replication initiator protein A
NIDDKIGC_03125 2.9e-35
NIDDKIGC_03126 4e-150 D CobQ CobB MinD ParA nucleotide binding domain protein
NIDDKIGC_03127 2.4e-104 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
NIDDKIGC_03129 2.6e-54 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
NIDDKIGC_03130 7.2e-24 L Integrase core domain
NIDDKIGC_03131 2.2e-33 L Transposase
NIDDKIGC_03132 5.2e-293 cadA P P-type ATPase
NIDDKIGC_03133 5.9e-22 cadA P P-type ATPase
NIDDKIGC_03134 6e-33
NIDDKIGC_03135 4e-47 L Psort location Cytoplasmic, score

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)