ORF_ID e_value Gene_name EC_number CAZy COGs Description
CMLFLONI_00001 1.3e-179 yaaC S YaaC-like Protein
CMLFLONI_00002 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
CMLFLONI_00003 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
CMLFLONI_00004 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
CMLFLONI_00005 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
CMLFLONI_00006 3.1e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
CMLFLONI_00007 1.3e-09
CMLFLONI_00008 8.3e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
CMLFLONI_00009 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
CMLFLONI_00010 2.4e-213 yaaH M Glycoside Hydrolase Family
CMLFLONI_00011 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
CMLFLONI_00012 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
CMLFLONI_00013 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMLFLONI_00014 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
CMLFLONI_00015 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CMLFLONI_00016 7.9e-32 yaaL S Protein of unknown function (DUF2508)
CMLFLONI_00017 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
CMLFLONI_00018 3.4e-31 csfB S Inhibitor of sigma-G Gin
CMLFLONI_00019 4.4e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
CMLFLONI_00020 8.4e-202 yaaN P Belongs to the TelA family
CMLFLONI_00021 5.1e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
CMLFLONI_00022 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
CMLFLONI_00023 2.2e-54 yaaQ S protein conserved in bacteria
CMLFLONI_00024 1.5e-71 yaaR S protein conserved in bacteria
CMLFLONI_00025 2.2e-182 holB 2.7.7.7 L DNA polymerase III
CMLFLONI_00026 6.1e-146 yaaT S stage 0 sporulation protein
CMLFLONI_00027 4.8e-31 yabA L Involved in initiation control of chromosome replication
CMLFLONI_00028 5.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
CMLFLONI_00029 1.5e-49 yazA L endonuclease containing a URI domain
CMLFLONI_00030 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
CMLFLONI_00031 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
CMLFLONI_00032 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CMLFLONI_00033 1.8e-144 tatD L hydrolase, TatD
CMLFLONI_00034 2e-167 rpfB GH23 T protein conserved in bacteria
CMLFLONI_00035 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
CMLFLONI_00036 3.4e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
CMLFLONI_00037 1.8e-135 yabG S peptidase
CMLFLONI_00038 7.8e-39 veg S protein conserved in bacteria
CMLFLONI_00039 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
CMLFLONI_00040 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
CMLFLONI_00041 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
CMLFLONI_00042 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
CMLFLONI_00043 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
CMLFLONI_00044 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CMLFLONI_00045 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
CMLFLONI_00046 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
CMLFLONI_00047 2.4e-39 yabK S Peptide ABC transporter permease
CMLFLONI_00048 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CMLFLONI_00049 1.5e-92 spoVT K stage V sporulation protein
CMLFLONI_00050 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_00051 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
CMLFLONI_00052 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
CMLFLONI_00053 1.5e-49 yabP S Sporulation protein YabP
CMLFLONI_00054 4.3e-107 yabQ S spore cortex biosynthesis protein
CMLFLONI_00055 1.1e-44 divIC D Septum formation initiator
CMLFLONI_00056 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
CMLFLONI_00059 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
CMLFLONI_00060 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
CMLFLONI_00061 4.1e-184 KLT serine threonine protein kinase
CMLFLONI_00062 1.2e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
CMLFLONI_00063 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
CMLFLONI_00064 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CMLFLONI_00065 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
CMLFLONI_00066 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CMLFLONI_00067 1.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
CMLFLONI_00068 1.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMLFLONI_00069 3.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMLFLONI_00070 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
CMLFLONI_00071 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
CMLFLONI_00072 8.5e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CMLFLONI_00073 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CMLFLONI_00074 6e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CMLFLONI_00075 4.1e-30 yazB K transcriptional
CMLFLONI_00076 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMLFLONI_00077 2.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
CMLFLONI_00078 2.9e-76 ctsR K Belongs to the CtsR family
CMLFLONI_00079 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
CMLFLONI_00080 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
CMLFLONI_00081 0.0 clpC O Belongs to the ClpA ClpB family
CMLFLONI_00082 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
CMLFLONI_00083 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
CMLFLONI_00084 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
CMLFLONI_00085 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
CMLFLONI_00086 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
CMLFLONI_00087 3.3e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CMLFLONI_00088 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
CMLFLONI_00089 1.6e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMLFLONI_00090 3e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
CMLFLONI_00091 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMLFLONI_00092 1.2e-88 yacP S RNA-binding protein containing a PIN domain
CMLFLONI_00093 4.4e-115 sigH K Belongs to the sigma-70 factor family
CMLFLONI_00094 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
CMLFLONI_00095 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
CMLFLONI_00096 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
CMLFLONI_00097 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
CMLFLONI_00098 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
CMLFLONI_00099 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
CMLFLONI_00100 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
CMLFLONI_00101 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLFLONI_00102 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLFLONI_00103 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
CMLFLONI_00104 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
CMLFLONI_00105 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
CMLFLONI_00106 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
CMLFLONI_00107 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
CMLFLONI_00108 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
CMLFLONI_00109 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
CMLFLONI_00110 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
CMLFLONI_00111 3e-105 rplD J Forms part of the polypeptide exit tunnel
CMLFLONI_00112 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
CMLFLONI_00113 7.2e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CMLFLONI_00114 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
CMLFLONI_00115 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
CMLFLONI_00116 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
CMLFLONI_00117 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
CMLFLONI_00118 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
CMLFLONI_00119 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
CMLFLONI_00120 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
CMLFLONI_00121 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
CMLFLONI_00122 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CMLFLONI_00123 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMLFLONI_00124 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
CMLFLONI_00125 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
CMLFLONI_00126 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CMLFLONI_00127 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
CMLFLONI_00128 1.9e-23 rpmD J Ribosomal protein L30
CMLFLONI_00129 1.8e-72 rplO J binds to the 23S rRNA
CMLFLONI_00130 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
CMLFLONI_00131 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
CMLFLONI_00132 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
CMLFLONI_00133 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
CMLFLONI_00134 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
CMLFLONI_00135 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CMLFLONI_00136 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
CMLFLONI_00137 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
CMLFLONI_00138 3.6e-58 rplQ J Ribosomal protein L17
CMLFLONI_00139 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLFLONI_00140 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLFLONI_00141 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
CMLFLONI_00142 2.6e-140 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
CMLFLONI_00143 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
CMLFLONI_00144 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
CMLFLONI_00145 5.3e-144 ybaJ Q Methyltransferase domain
CMLFLONI_00146 9.7e-66 ybaK S Protein of unknown function (DUF2521)
CMLFLONI_00147 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CMLFLONI_00148 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
CMLFLONI_00149 1.2e-84 gerD
CMLFLONI_00150 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
CMLFLONI_00151 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
CMLFLONI_00152 7.9e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
CMLFLONI_00154 1.7e-160 ybaS 1.1.1.58 S Na -dependent transporter
CMLFLONI_00155 1.2e-137 ybbA S Putative esterase
CMLFLONI_00156 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00157 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00158 2e-164 feuA P Iron-uptake system-binding protein
CMLFLONI_00159 2.8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
CMLFLONI_00160 3.9e-237 ybbC 3.2.1.52 S protein conserved in bacteria
CMLFLONI_00161 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
CMLFLONI_00162 1.3e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
CMLFLONI_00163 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_00164 2.5e-150 ybbH K transcriptional
CMLFLONI_00165 3.3e-161 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
CMLFLONI_00166 1.9e-86 ybbJ J acetyltransferase
CMLFLONI_00167 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
CMLFLONI_00173 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_00174 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
CMLFLONI_00175 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMLFLONI_00176 9.8e-224 ybbR S protein conserved in bacteria
CMLFLONI_00177 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CMLFLONI_00178 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
CMLFLONI_00179 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CMLFLONI_00180 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
CMLFLONI_00181 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMLFLONI_00182 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CMLFLONI_00183 0.0 ybcC S Belongs to the UPF0753 family
CMLFLONI_00184 1.1e-92 can 4.2.1.1 P carbonic anhydrase
CMLFLONI_00185 6.2e-45
CMLFLONI_00186 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
CMLFLONI_00187 5.1e-50 ybzH K Helix-turn-helix domain
CMLFLONI_00188 3.5e-203 ybcL EGP Major facilitator Superfamily
CMLFLONI_00189 4.9e-57
CMLFLONI_00191 3.7e-137 KLT Protein tyrosine kinase
CMLFLONI_00192 3.8e-151 ybdN
CMLFLONI_00193 2.2e-213 ybdO S Domain of unknown function (DUF4885)
CMLFLONI_00194 1.7e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_00195 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
CMLFLONI_00196 4.9e-30 ybxH S Family of unknown function (DUF5370)
CMLFLONI_00197 3e-150 ybxI 3.5.2.6 V beta-lactamase
CMLFLONI_00198 3.6e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
CMLFLONI_00199 4.9e-41 ybyB
CMLFLONI_00200 6.8e-290 ybeC E amino acid
CMLFLONI_00201 1e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMLFLONI_00202 7.3e-258 glpT G -transporter
CMLFLONI_00203 1.5e-34 S Protein of unknown function (DUF2651)
CMLFLONI_00204 2.8e-168 ybfA 3.4.15.5 K FR47-like protein
CMLFLONI_00205 7.9e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
CMLFLONI_00207 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
CMLFLONI_00208 3.7e-160 ybfH EG EamA-like transporter family
CMLFLONI_00209 3.3e-144 msmR K AraC-like ligand binding domain
CMLFLONI_00210 8e-148 draG 3.2.2.24 O ADP-ribosylglycohydrolase
CMLFLONI_00211 1.8e-77 M nucleic acid phosphodiester bond hydrolysis
CMLFLONI_00212 5.2e-212 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
CMLFLONI_00213 5.8e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
CMLFLONI_00215 4.4e-166 S Alpha/beta hydrolase family
CMLFLONI_00216 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMLFLONI_00217 2.7e-85 ybfM S SNARE associated Golgi protein
CMLFLONI_00218 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
CMLFLONI_00219 4.6e-45 ybfN
CMLFLONI_00220 1.3e-249 S Erythromycin esterase
CMLFLONI_00221 3.9e-192 yceA S Belongs to the UPF0176 family
CMLFLONI_00222 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMLFLONI_00223 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_00224 9.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMLFLONI_00225 1.4e-127 K UTRA
CMLFLONI_00226 4.5e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CMLFLONI_00227 6.7e-262 mmuP E amino acid
CMLFLONI_00228 2.3e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
CMLFLONI_00230 1.4e-254 agcS E Sodium alanine symporter
CMLFLONI_00231 1.4e-186 glsA 3.5.1.2 E Belongs to the glutaminase family
CMLFLONI_00232 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
CMLFLONI_00233 9e-170 glnL T Regulator
CMLFLONI_00234 5e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
CMLFLONI_00235 3.1e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CMLFLONI_00236 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
CMLFLONI_00237 2.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CMLFLONI_00238 6.1e-123 ycbG K FCD
CMLFLONI_00239 1.7e-295 garD 4.2.1.42, 4.2.1.7 G Altronate
CMLFLONI_00240 2.6e-177 ycbJ S Macrolide 2'-phosphotransferase
CMLFLONI_00241 5.7e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
CMLFLONI_00242 3.4e-169 eamA1 EG spore germination
CMLFLONI_00243 3.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_00244 3.2e-167 T PhoQ Sensor
CMLFLONI_00245 5e-165 ycbN V ABC transporter, ATP-binding protein
CMLFLONI_00246 5.1e-114 S ABC-2 family transporter protein
CMLFLONI_00247 8.2e-53 ycbP S Protein of unknown function (DUF2512)
CMLFLONI_00248 2.2e-78 sleB 3.5.1.28 M Cell wall
CMLFLONI_00249 6.6e-136 ycbR T vWA found in TerF C terminus
CMLFLONI_00250 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
CMLFLONI_00251 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CMLFLONI_00252 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMLFLONI_00253 6.5e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CMLFLONI_00254 2.7e-205 ycbU E Selenocysteine lyase
CMLFLONI_00255 7.9e-226 lmrB EGP the major facilitator superfamily
CMLFLONI_00256 7e-101 yxaF K Transcriptional regulator
CMLFLONI_00257 3.4e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
CMLFLONI_00258 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CMLFLONI_00259 3.4e-59 S RDD family
CMLFLONI_00260 1.4e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
CMLFLONI_00261 6.6e-152 2.7.13.3 T GHKL domain
CMLFLONI_00262 1.2e-126 lytR_2 T LytTr DNA-binding domain
CMLFLONI_00263 3.4e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
CMLFLONI_00264 2.9e-202 natB CP ABC-2 family transporter protein
CMLFLONI_00265 1e-173 yccK C Aldo keto reductase
CMLFLONI_00266 6.6e-177 ycdA S Domain of unknown function (DUF5105)
CMLFLONI_00267 6.1e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_00268 4.8e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_00269 1.6e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
CMLFLONI_00270 1e-172 S response regulator aspartate phosphatase
CMLFLONI_00271 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_00272 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
CMLFLONI_00273 2.1e-166 adcA P Belongs to the bacterial solute-binding protein 9 family
CMLFLONI_00274 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CMLFLONI_00275 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CMLFLONI_00276 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_00277 1.6e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
CMLFLONI_00278 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
CMLFLONI_00279 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
CMLFLONI_00280 1.4e-136 terC P Protein of unknown function (DUF475)
CMLFLONI_00281 0.0 yceG S Putative component of 'biosynthetic module'
CMLFLONI_00282 2e-192 yceH P Belongs to the TelA family
CMLFLONI_00283 1.1e-217 naiP P Uncharacterised MFS-type transporter YbfB
CMLFLONI_00284 5.7e-206 yceJ EGP Uncharacterised MFS-type transporter YbfB
CMLFLONI_00285 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
CMLFLONI_00286 4.8e-227 proV 3.6.3.32 E glycine betaine
CMLFLONI_00287 1.3e-127 opuAB P glycine betaine
CMLFLONI_00288 5.3e-164 opuAC E glycine betaine
CMLFLONI_00289 4.1e-217 amhX S amidohydrolase
CMLFLONI_00290 5.6e-256 ycgA S Membrane
CMLFLONI_00291 4.1e-81 ycgB
CMLFLONI_00292 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
CMLFLONI_00293 1.2e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
CMLFLONI_00294 6.5e-293 lctP C L-lactate permease
CMLFLONI_00295 6.2e-269 mdr EGP Major facilitator Superfamily
CMLFLONI_00296 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_00297 6.8e-113 ycgF E Lysine exporter protein LysE YggA
CMLFLONI_00298 1.2e-151 yqcI S YqcI/YcgG family
CMLFLONI_00299 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_00300 2.4e-112 ycgI S Domain of unknown function (DUF1989)
CMLFLONI_00301 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
CMLFLONI_00302 1e-41 tmrB S AAA domain
CMLFLONI_00303 7.5e-17 tmrB S AAA domain
CMLFLONI_00305 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
CMLFLONI_00306 4.4e-143 yafE Q ubiE/COQ5 methyltransferase family
CMLFLONI_00307 1.5e-175 oxyR3 K LysR substrate binding domain
CMLFLONI_00308 2.7e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
CMLFLONI_00309 7.8e-143 ycgL S Predicted nucleotidyltransferase
CMLFLONI_00310 5.1e-170 ycgM E Proline dehydrogenase
CMLFLONI_00311 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CMLFLONI_00312 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMLFLONI_00313 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
CMLFLONI_00314 1.3e-146 ycgQ S membrane
CMLFLONI_00315 6.5e-138 ycgR S permeases
CMLFLONI_00316 1.6e-157 I alpha/beta hydrolase fold
CMLFLONI_00317 3e-187 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
CMLFLONI_00318 2.3e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CMLFLONI_00319 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
CMLFLONI_00320 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CMLFLONI_00321 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CMLFLONI_00322 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
CMLFLONI_00323 2.9e-221 nasA P COG2223 Nitrate nitrite transporter
CMLFLONI_00324 6.7e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
CMLFLONI_00325 2e-106 yciB M ErfK YbiS YcfS YnhG
CMLFLONI_00326 7e-228 yciC S GTPases (G3E family)
CMLFLONI_00327 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
CMLFLONI_00328 3.4e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
CMLFLONI_00330 9.6e-77 yckC S membrane
CMLFLONI_00331 3.5e-52 yckD S Protein of unknown function (DUF2680)
CMLFLONI_00332 6.1e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMLFLONI_00333 1.7e-69 nin S Competence protein J (ComJ)
CMLFLONI_00334 5.1e-70 nucA M Deoxyribonuclease NucA/NucB
CMLFLONI_00335 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
CMLFLONI_00336 3.3e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
CMLFLONI_00337 8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
CMLFLONI_00338 8.2e-63 hxlR K transcriptional
CMLFLONI_00339 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_00340 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_00341 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_00342 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
CMLFLONI_00343 5.7e-140 srfAD Q thioesterase
CMLFLONI_00344 2e-225 EGP Major Facilitator Superfamily
CMLFLONI_00345 9.6e-87 S YcxB-like protein
CMLFLONI_00346 2.9e-160 ycxC EG EamA-like transporter family
CMLFLONI_00347 5.6e-250 ycxD K GntR family transcriptional regulator
CMLFLONI_00348 1.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
CMLFLONI_00349 1.7e-114 yczE S membrane
CMLFLONI_00350 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CMLFLONI_00351 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
CMLFLONI_00352 2e-125 tcyA ET Belongs to the bacterial solute-binding protein 3 family
CMLFLONI_00353 1.9e-161 bsdA K LysR substrate binding domain
CMLFLONI_00354 1.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
CMLFLONI_00355 3.1e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
CMLFLONI_00356 4e-39 bsdD 4.1.1.61 S response to toxic substance
CMLFLONI_00357 2.5e-80 yclD
CMLFLONI_00358 6.6e-156 yclE 3.4.11.5 S Alpha beta hydrolase
CMLFLONI_00359 3.2e-262 dtpT E amino acid peptide transporter
CMLFLONI_00360 2.5e-298 yclG M Pectate lyase superfamily protein
CMLFLONI_00362 5.4e-279 gerKA EG Spore germination protein
CMLFLONI_00363 1.4e-223 gerKC S spore germination
CMLFLONI_00364 1.8e-193 gerKB F Spore germination protein
CMLFLONI_00365 1.6e-120 yclH P ABC transporter
CMLFLONI_00366 3.7e-199 yclI V ABC transporter (permease) YclI
CMLFLONI_00367 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_00368 4.4e-261 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
CMLFLONI_00369 8.6e-74 S aspartate phosphatase
CMLFLONI_00372 2.7e-239 lysC 2.7.2.4 E Belongs to the aspartokinase family
CMLFLONI_00373 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00374 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00375 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
CMLFLONI_00376 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
CMLFLONI_00377 3.2e-251 ycnB EGP Major facilitator Superfamily
CMLFLONI_00378 4.2e-153 ycnC K Transcriptional regulator
CMLFLONI_00379 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
CMLFLONI_00380 2.8e-45 ycnE S Monooxygenase
CMLFLONI_00381 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
CMLFLONI_00382 5.1e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_00383 3.4e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CMLFLONI_00384 1.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CMLFLONI_00385 6.1e-149 glcU U Glucose uptake
CMLFLONI_00386 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_00387 9.3e-99 ycnI S protein conserved in bacteria
CMLFLONI_00388 3.9e-306 ycnJ P protein, homolog of Cu resistance protein CopC
CMLFLONI_00389 3.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
CMLFLONI_00390 2.6e-53
CMLFLONI_00391 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
CMLFLONI_00392 3.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
CMLFLONI_00393 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
CMLFLONI_00394 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
CMLFLONI_00395 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CMLFLONI_00396 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CMLFLONI_00397 1.4e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
CMLFLONI_00398 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
CMLFLONI_00400 1.5e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
CMLFLONI_00401 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
CMLFLONI_00402 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
CMLFLONI_00403 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
CMLFLONI_00404 1.2e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
CMLFLONI_00405 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
CMLFLONI_00406 1.2e-132 kipR K Transcriptional regulator
CMLFLONI_00407 4.9e-119 ycsK E anatomical structure formation involved in morphogenesis
CMLFLONI_00409 5.4e-49 yczJ S biosynthesis
CMLFLONI_00410 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
CMLFLONI_00411 3.4e-174 ydhF S Oxidoreductase
CMLFLONI_00412 0.0 mtlR K transcriptional regulator, MtlR
CMLFLONI_00413 1.8e-292 ydaB IQ acyl-CoA ligase
CMLFLONI_00414 1.1e-99 ydaC Q Methyltransferase domain
CMLFLONI_00415 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_00416 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
CMLFLONI_00417 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CMLFLONI_00418 6.8e-77 ydaG 1.4.3.5 S general stress protein
CMLFLONI_00419 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
CMLFLONI_00420 5.1e-47 ydzA EGP Major facilitator Superfamily
CMLFLONI_00421 2.5e-74 lrpC K Transcriptional regulator
CMLFLONI_00422 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMLFLONI_00423 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
CMLFLONI_00424 3.6e-149 ydaK T Diguanylate cyclase, GGDEF domain
CMLFLONI_00425 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
CMLFLONI_00426 1.3e-232 ydaM M Glycosyl transferase family group 2
CMLFLONI_00427 0.0 ydaN S Bacterial cellulose synthase subunit
CMLFLONI_00428 0.0 ydaO E amino acid
CMLFLONI_00429 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
CMLFLONI_00430 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
CMLFLONI_00431 4.7e-39
CMLFLONI_00432 5e-224 mntH P H( )-stimulated, divalent metal cation uptake system
CMLFLONI_00434 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
CMLFLONI_00435 2.4e-147 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
CMLFLONI_00437 8.9e-59 ydbB G Cupin domain
CMLFLONI_00438 3.1e-62 ydbC S Domain of unknown function (DUF4937
CMLFLONI_00439 3.5e-154 ydbD P Catalase
CMLFLONI_00440 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
CMLFLONI_00441 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CMLFLONI_00442 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
CMLFLONI_00443 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMLFLONI_00444 9.7e-181 ydbI S AI-2E family transporter
CMLFLONI_00445 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
CMLFLONI_00446 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CMLFLONI_00447 2.7e-52 ydbL
CMLFLONI_00448 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
CMLFLONI_00449 1.1e-18 S Fur-regulated basic protein B
CMLFLONI_00450 2.2e-07 S Fur-regulated basic protein A
CMLFLONI_00451 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMLFLONI_00452 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMLFLONI_00453 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
CMLFLONI_00454 3.4e-253 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
CMLFLONI_00455 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
CMLFLONI_00456 2.1e-82 ydbS S Bacterial PH domain
CMLFLONI_00457 3.7e-263 ydbT S Membrane
CMLFLONI_00458 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
CMLFLONI_00459 4.7e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
CMLFLONI_00460 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
CMLFLONI_00461 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMLFLONI_00462 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
CMLFLONI_00463 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
CMLFLONI_00464 1.3e-143 rsbR T Positive regulator of sigma-B
CMLFLONI_00465 5.2e-57 rsbS T antagonist
CMLFLONI_00466 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
CMLFLONI_00467 7.1e-189 rsbU 3.1.3.3 KT phosphatase
CMLFLONI_00468 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
CMLFLONI_00469 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
CMLFLONI_00470 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_00471 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
CMLFLONI_00472 0.0 yhgF K COG2183 Transcriptional accessory protein
CMLFLONI_00473 8.9e-83 ydcK S Belongs to the SprT family
CMLFLONI_00481 3.1e-86 L Phage integrase family
CMLFLONI_00482 9.4e-25 S Domain of unknown function with cystatin-like fold (DUF4467)
CMLFLONI_00483 1.8e-156 3.6.4.12 L HELICc2
CMLFLONI_00485 1.6e-50
CMLFLONI_00486 8e-47 S SMI1-KNR4 cell-wall
CMLFLONI_00487 1.1e-44
CMLFLONI_00488 1.4e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CMLFLONI_00489 1.9e-69 L HNH nucleases
CMLFLONI_00491 1.7e-32 K Helix-turn-helix XRE-family like proteins
CMLFLONI_00492 4.6e-42
CMLFLONI_00493 3.5e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CMLFLONI_00494 8.7e-30 cspL K Cold shock
CMLFLONI_00495 6.1e-79 carD K Transcription factor
CMLFLONI_00496 1.4e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CMLFLONI_00497 1.2e-163 rhaS5 K AraC-like ligand binding domain
CMLFLONI_00498 3.7e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
CMLFLONI_00499 6.2e-165 ydeE K AraC family transcriptional regulator
CMLFLONI_00500 2.8e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_00501 4.6e-217 ydeG EGP Major facilitator superfamily
CMLFLONI_00502 5.2e-44 ydeH
CMLFLONI_00503 3.9e-102 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
CMLFLONI_00504 4.4e-107
CMLFLONI_00505 4.9e-15 ptsH G PTS HPr component phosphorylation site
CMLFLONI_00506 2.3e-85 K Transcriptional regulator C-terminal region
CMLFLONI_00507 5e-151 ydeK EG -transporter
CMLFLONI_00508 1.1e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_00509 1.3e-72 maoC I N-terminal half of MaoC dehydratase
CMLFLONI_00510 1.2e-103 ydeN S Serine hydrolase
CMLFLONI_00511 1.2e-55 K HxlR-like helix-turn-helix
CMLFLONI_00512 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CMLFLONI_00513 1.8e-68 ydeP K Transcriptional regulator
CMLFLONI_00514 1.9e-109 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
CMLFLONI_00515 2.8e-184 ydeR EGP Major facilitator Superfamily
CMLFLONI_00516 1e-102 ydeS K Transcriptional regulator
CMLFLONI_00517 2.8e-57 arsR K transcriptional
CMLFLONI_00518 3.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CMLFLONI_00519 3.4e-146 ydfB J GNAT acetyltransferase
CMLFLONI_00520 2.4e-151 ydfC EG EamA-like transporter family
CMLFLONI_00521 6.7e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_00522 1.4e-115 ydfE S Flavin reductase like domain
CMLFLONI_00523 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
CMLFLONI_00524 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CMLFLONI_00526 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
CMLFLONI_00527 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_00528 0.0 ydfJ S drug exporters of the RND superfamily
CMLFLONI_00529 1.4e-175 S Alpha/beta hydrolase family
CMLFLONI_00530 8.5e-117 S Protein of unknown function (DUF554)
CMLFLONI_00531 9.2e-147 K Bacterial transcription activator, effector binding domain
CMLFLONI_00532 7.8e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMLFLONI_00533 1.4e-110 ydfN C nitroreductase
CMLFLONI_00534 1.2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
CMLFLONI_00535 8.8e-63 mhqP S DoxX
CMLFLONI_00536 7e-56 traF CO Thioredoxin
CMLFLONI_00538 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
CMLFLONI_00539 6.3e-29
CMLFLONI_00541 4.4e-118 ydfR S Protein of unknown function (DUF421)
CMLFLONI_00542 5.2e-122 ydfS S Protein of unknown function (DUF421)
CMLFLONI_00543 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
CMLFLONI_00544 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
CMLFLONI_00545 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
CMLFLONI_00546 2.8e-100 K Bacterial regulatory proteins, tetR family
CMLFLONI_00547 9.6e-53 S DoxX-like family
CMLFLONI_00548 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
CMLFLONI_00549 3e-298 expZ S ABC transporter
CMLFLONI_00550 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_00551 8.7e-90 dinB S DinB family
CMLFLONI_00552 1.4e-78 K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_00553 0.0 ydgH S drug exporters of the RND superfamily
CMLFLONI_00554 1e-113 drgA C nitroreductase
CMLFLONI_00555 2.4e-69 ydgJ K Winged helix DNA-binding domain
CMLFLONI_00556 7.4e-209 tcaB EGP Major facilitator Superfamily
CMLFLONI_00557 1.2e-121 ydhB S membrane transporter protein
CMLFLONI_00558 6.5e-122 ydhC K FCD
CMLFLONI_00559 4.1e-242 ydhD M Glycosyl hydrolase
CMLFLONI_00560 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CMLFLONI_00561 5.1e-125
CMLFLONI_00562 1.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CMLFLONI_00563 2.3e-68 frataxin S Domain of unknown function (DU1801)
CMLFLONI_00565 3.5e-85 K Acetyltransferase (GNAT) domain
CMLFLONI_00566 1.9e-178 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
CMLFLONI_00567 1.4e-96 ydhK M Protein of unknown function (DUF1541)
CMLFLONI_00568 7.9e-200 pbuE EGP Major facilitator Superfamily
CMLFLONI_00569 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
CMLFLONI_00570 4.3e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
CMLFLONI_00571 2.6e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLFLONI_00572 1.2e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMLFLONI_00573 1.3e-131 ydhQ K UTRA
CMLFLONI_00574 6.2e-168 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
CMLFLONI_00575 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMLFLONI_00576 9.9e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
CMLFLONI_00577 1.5e-118 ydhU P Catalase
CMLFLONI_00578 9.3e-18 ydhU P Manganese containing catalase
CMLFLONI_00581 7.8e-08
CMLFLONI_00583 9e-181 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CMLFLONI_00584 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
CMLFLONI_00585 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
CMLFLONI_00586 3.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
CMLFLONI_00587 3.9e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
CMLFLONI_00588 0.0 ydiF S ABC transporter
CMLFLONI_00589 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
CMLFLONI_00590 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
CMLFLONI_00591 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
CMLFLONI_00592 1.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
CMLFLONI_00593 2.9e-27 ydiK S Domain of unknown function (DUF4305)
CMLFLONI_00594 7.9e-129 ydiL S CAAX protease self-immunity
CMLFLONI_00595 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
CMLFLONI_00596 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
CMLFLONI_00597 3.6e-153 ydjC S Abhydrolase domain containing 18
CMLFLONI_00598 0.0 K NB-ARC domain
CMLFLONI_00599 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
CMLFLONI_00600 6.7e-254 gutA G MFS/sugar transport protein
CMLFLONI_00601 1.5e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
CMLFLONI_00602 1.1e-113 pspA KT Phage shock protein A
CMLFLONI_00603 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMLFLONI_00604 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
CMLFLONI_00605 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
CMLFLONI_00606 4.7e-196 S Ion transport 2 domain protein
CMLFLONI_00607 2.7e-258 iolT EGP Major facilitator Superfamily
CMLFLONI_00608 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
CMLFLONI_00609 4.5e-64 ydjM M Lytic transglycolase
CMLFLONI_00610 3.3e-149 ydjN U Involved in the tonB-independent uptake of proteins
CMLFLONI_00612 1.4e-34 ydjO S Cold-inducible protein YdjO
CMLFLONI_00613 9.5e-160 ydjP I Alpha/beta hydrolase family
CMLFLONI_00614 1.4e-176 yeaA S Protein of unknown function (DUF4003)
CMLFLONI_00615 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
CMLFLONI_00616 5.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_00617 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
CMLFLONI_00618 1.7e-176 yeaC S COG0714 MoxR-like ATPases
CMLFLONI_00619 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
CMLFLONI_00620 0.0 yebA E COG1305 Transglutaminase-like enzymes
CMLFLONI_00621 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
CMLFLONI_00622 1.3e-211 pbuG S permease
CMLFLONI_00623 2.3e-118 yebC M Membrane
CMLFLONI_00625 4e-93 yebE S UPF0316 protein
CMLFLONI_00626 8e-28 yebG S NETI protein
CMLFLONI_00627 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CMLFLONI_00628 4.2e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CMLFLONI_00629 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CMLFLONI_00630 2.8e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
CMLFLONI_00631 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMLFLONI_00632 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMLFLONI_00633 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CMLFLONI_00634 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
CMLFLONI_00635 1.4e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
CMLFLONI_00636 1.8e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CMLFLONI_00637 8.6e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
CMLFLONI_00638 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
CMLFLONI_00639 1e-72 K helix_turn_helix ASNC type
CMLFLONI_00640 1.3e-227 yjeH E Amino acid permease
CMLFLONI_00641 2.7e-27 S Protein of unknown function (DUF2892)
CMLFLONI_00642 0.0 yerA 3.5.4.2 F adenine deaminase
CMLFLONI_00643 1.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
CMLFLONI_00644 4.8e-51 yerC S protein conserved in bacteria
CMLFLONI_00645 2.3e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
CMLFLONI_00647 1.1e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
CMLFLONI_00648 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
CMLFLONI_00649 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
CMLFLONI_00650 2e-219 camS S COG4851 Protein involved in sex pheromone biosynthesis
CMLFLONI_00651 3.2e-197 yerI S homoserine kinase type II (protein kinase fold)
CMLFLONI_00652 1.6e-123 sapB S MgtC SapB transporter
CMLFLONI_00653 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMLFLONI_00654 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMLFLONI_00655 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
CMLFLONI_00656 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CMLFLONI_00657 1.3e-148 yerO K Transcriptional regulator
CMLFLONI_00658 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CMLFLONI_00659 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CMLFLONI_00660 2.5e-253 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMLFLONI_00661 3e-151 2.1.1.37 L C-5 cytosine-specific DNA methylase
CMLFLONI_00662 2.8e-143 3.1.21.4 S type ii restriction enzyme
CMLFLONI_00664 8.7e-42 S Immunity protein 22
CMLFLONI_00665 1.6e-186 yobL S Bacterial EndoU nuclease
CMLFLONI_00667 4.5e-122 3.4.24.40 CO amine dehydrogenase activity
CMLFLONI_00668 4.6e-40
CMLFLONI_00669 1.2e-208 S Tetratricopeptide repeat
CMLFLONI_00671 2.7e-126 yeeN K transcriptional regulatory protein
CMLFLONI_00673 8e-100 dhaR3 K Transcriptional regulator
CMLFLONI_00674 1.1e-77 yesE S SnoaL-like domain
CMLFLONI_00675 2.5e-150 yesF GM NAD(P)H-binding
CMLFLONI_00676 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
CMLFLONI_00677 1.5e-45 cotJB S CotJB protein
CMLFLONI_00678 5.2e-104 cotJC P Spore Coat
CMLFLONI_00679 3e-101 yesJ K Acetyltransferase (GNAT) family
CMLFLONI_00680 9.2e-102 yesL S Protein of unknown function, DUF624
CMLFLONI_00681 0.0 yesM 2.7.13.3 T Histidine kinase
CMLFLONI_00682 6.8e-201 yesN K helix_turn_helix, arabinose operon control protein
CMLFLONI_00683 6.2e-246 yesO G Bacterial extracellular solute-binding protein
CMLFLONI_00684 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
CMLFLONI_00685 1.2e-163 yesQ P Binding-protein-dependent transport system inner membrane component
CMLFLONI_00686 3.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
CMLFLONI_00687 2.4e-133 yesS K Transcriptional regulator
CMLFLONI_00688 1.6e-269 yesS K Transcriptional regulator
CMLFLONI_00689 7.9e-131 E GDSL-like Lipase/Acylhydrolase
CMLFLONI_00690 6e-128 yesU S Domain of unknown function (DUF1961)
CMLFLONI_00691 9.7e-112 yesV S Protein of unknown function, DUF624
CMLFLONI_00692 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CMLFLONI_00693 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
CMLFLONI_00695 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
CMLFLONI_00696 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
CMLFLONI_00697 0.0 yetA
CMLFLONI_00698 4e-289 lplA G Bacterial extracellular solute-binding protein
CMLFLONI_00699 3.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CMLFLONI_00700 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
CMLFLONI_00701 1.2e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CMLFLONI_00702 8.8e-122 yetF S membrane
CMLFLONI_00703 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
CMLFLONI_00704 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_00705 2.2e-34
CMLFLONI_00706 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CMLFLONI_00707 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
CMLFLONI_00708 4.5e-104 yetJ S Belongs to the BI1 family
CMLFLONI_00709 1.4e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_00710 3e-209 yetM CH FAD binding domain
CMLFLONI_00712 3e-193 yetN S Protein of unknown function (DUF3900)
CMLFLONI_00713 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CMLFLONI_00714 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CMLFLONI_00715 7.4e-146 rfbF 2.7.7.33 JM Nucleotidyl transferase
CMLFLONI_00716 3.2e-172 yfnG 4.2.1.45 M dehydratase
CMLFLONI_00717 5.1e-178 yfnF M Nucleotide-diphospho-sugar transferase
CMLFLONI_00718 1.2e-224 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
CMLFLONI_00719 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
CMLFLONI_00720 8.6e-205 fsr P COG0477 Permeases of the major facilitator superfamily
CMLFLONI_00721 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
CMLFLONI_00722 1.4e-240 yfnA E amino acid
CMLFLONI_00723 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CMLFLONI_00724 1.1e-113 yfmS NT chemotaxis protein
CMLFLONI_00725 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CMLFLONI_00726 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
CMLFLONI_00727 2.8e-70 yfmP K transcriptional
CMLFLONI_00728 4.3e-209 yfmO EGP Major facilitator Superfamily
CMLFLONI_00729 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CMLFLONI_00730 2.9e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
CMLFLONI_00731 3.1e-80 yfmK 2.3.1.128 K acetyltransferase
CMLFLONI_00732 9.4e-189 yfmJ S N-terminal domain of oxidoreductase
CMLFLONI_00733 7.7e-214 G Major Facilitator Superfamily
CMLFLONI_00734 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
CMLFLONI_00735 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
CMLFLONI_00736 2e-167 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00737 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00738 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
CMLFLONI_00739 7.2e-23 S Protein of unknown function (DUF3212)
CMLFLONI_00740 1.3e-57 yflT S Heat induced stress protein YflT
CMLFLONI_00741 1.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
CMLFLONI_00742 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
CMLFLONI_00743 3.5e-286 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CMLFLONI_00744 2.6e-118 citT T response regulator
CMLFLONI_00745 2.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
CMLFLONI_00746 8.5e-227 citM C Citrate transporter
CMLFLONI_00747 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
CMLFLONI_00748 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
CMLFLONI_00749 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
CMLFLONI_00750 9.9e-123 yflK S protein conserved in bacteria
CMLFLONI_00751 4e-18 yflJ S Protein of unknown function (DUF2639)
CMLFLONI_00752 5.4e-19 yflI
CMLFLONI_00753 9.1e-50 yflH S Protein of unknown function (DUF3243)
CMLFLONI_00754 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
CMLFLONI_00755 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
CMLFLONI_00756 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CMLFLONI_00757 6e-67 yhdN S Domain of unknown function (DUF1992)
CMLFLONI_00758 2.2e-252 agcS_1 E Sodium alanine symporter
CMLFLONI_00759 1.9e-192 E Spore germination protein
CMLFLONI_00761 1.5e-206 yfkR S spore germination
CMLFLONI_00762 2.9e-282 yfkQ EG Spore germination protein
CMLFLONI_00763 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_00764 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
CMLFLONI_00765 1.8e-133 treR K transcriptional
CMLFLONI_00766 1.6e-125 yfkO C nitroreductase
CMLFLONI_00767 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
CMLFLONI_00768 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
CMLFLONI_00769 4.4e-206 ydiM EGP Major facilitator Superfamily
CMLFLONI_00770 2.3e-28 yfkK S Belongs to the UPF0435 family
CMLFLONI_00771 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMLFLONI_00772 9.2e-50 yfkI S gas vesicle protein
CMLFLONI_00773 9.7e-144 yihY S Belongs to the UPF0761 family
CMLFLONI_00774 5e-08
CMLFLONI_00775 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
CMLFLONI_00776 6.1e-183 cax P COG0387 Ca2 H antiporter
CMLFLONI_00777 1.2e-146 yfkD S YfkD-like protein
CMLFLONI_00778 3e-148 yfkC M Mechanosensitive ion channel
CMLFLONI_00779 5.4e-222 yfkA S YfkB-like domain
CMLFLONI_00780 1.1e-26 yfjT
CMLFLONI_00781 1.7e-153 pdaA G deacetylase
CMLFLONI_00782 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
CMLFLONI_00783 1.7e-184 corA P Mediates influx of magnesium ions
CMLFLONI_00784 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
CMLFLONI_00785 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
CMLFLONI_00786 3.9e-44 S YfzA-like protein
CMLFLONI_00787 1.8e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CMLFLONI_00788 1.9e-85 yfjM S Psort location Cytoplasmic, score
CMLFLONI_00789 2.6e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CMLFLONI_00790 1.9e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CMLFLONI_00791 1.3e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMLFLONI_00792 1.4e-251 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CMLFLONI_00793 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
CMLFLONI_00794 9.8e-25 sspH S Belongs to the SspH family
CMLFLONI_00795 4e-56 yfjF S UPF0060 membrane protein
CMLFLONI_00796 1.9e-79 S Family of unknown function (DUF5381)
CMLFLONI_00797 1.8e-101 yfjD S Family of unknown function (DUF5381)
CMLFLONI_00798 4.1e-144 yfjC
CMLFLONI_00799 2.3e-189 yfjB
CMLFLONI_00800 1.1e-44 yfjA S Belongs to the WXG100 family
CMLFLONI_00801 2.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CMLFLONI_00802 1e-139 glvR K Helix-turn-helix domain, rpiR family
CMLFLONI_00803 8e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_00804 0.0 yobO M COG5434 Endopolygalacturonase
CMLFLONI_00805 4.4e-308 yfiB3 V ABC transporter
CMLFLONI_00806 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
CMLFLONI_00807 1.1e-63 mhqP S DoxX
CMLFLONI_00808 3.5e-160 yfiE 1.13.11.2 S glyoxalase
CMLFLONI_00809 7.7e-187 yxjM T Histidine kinase
CMLFLONI_00810 5.4e-113 KT LuxR family transcriptional regulator
CMLFLONI_00811 8.9e-170 V ABC transporter, ATP-binding protein
CMLFLONI_00812 6.8e-207 V ABC-2 family transporter protein
CMLFLONI_00813 3.8e-202 V COG0842 ABC-type multidrug transport system, permease component
CMLFLONI_00814 8.3e-99 padR K transcriptional
CMLFLONI_00815 1.7e-79 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
CMLFLONI_00816 8.4e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
CMLFLONI_00817 1.2e-99 yfiT S Belongs to the metal hydrolase YfiT family
CMLFLONI_00818 3.8e-282 yfiU EGP Major facilitator Superfamily
CMLFLONI_00819 4.9e-79 yfiV K transcriptional
CMLFLONI_00820 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CMLFLONI_00821 8.2e-174 yfiY P ABC transporter substrate-binding protein
CMLFLONI_00822 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00823 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_00824 1.8e-167 yfhB 5.3.3.17 S PhzF family
CMLFLONI_00825 1.5e-106 yfhC C nitroreductase
CMLFLONI_00826 6.1e-25 yfhD S YfhD-like protein
CMLFLONI_00828 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
CMLFLONI_00829 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
CMLFLONI_00830 9.7e-52 yfhH S Protein of unknown function (DUF1811)
CMLFLONI_00832 1.1e-209 yfhI EGP Major facilitator Superfamily
CMLFLONI_00833 6.2e-20 sspK S reproduction
CMLFLONI_00834 1.3e-44 yfhJ S WVELL protein
CMLFLONI_00835 2.4e-87 batE T Bacterial SH3 domain homologues
CMLFLONI_00836 3.5e-51 yfhL S SdpI/YhfL protein family
CMLFLONI_00837 1.3e-170 yfhM S Alpha beta hydrolase
CMLFLONI_00838 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_00839 0.0 yfhO S Bacterial membrane protein YfhO
CMLFLONI_00840 1.2e-185 yfhP S membrane-bound metal-dependent
CMLFLONI_00841 3.3e-210 mutY L A G-specific
CMLFLONI_00842 6.9e-36 yfhS
CMLFLONI_00843 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_00844 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
CMLFLONI_00845 1.1e-47 ygaB S YgaB-like protein
CMLFLONI_00846 1.3e-104 ygaC J Belongs to the UPF0374 family
CMLFLONI_00847 3.1e-301 ygaD V ABC transporter
CMLFLONI_00848 8.7e-180 ygaE S Membrane
CMLFLONI_00849 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CMLFLONI_00850 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
CMLFLONI_00851 4e-80 perR P Belongs to the Fur family
CMLFLONI_00852 8.1e-55 ygzB S UPF0295 protein
CMLFLONI_00853 6.7e-167 ygxA S Nucleotidyltransferase-like
CMLFLONI_00858 7.8e-08
CMLFLONI_00866 2e-08
CMLFLONI_00870 1.9e-141 spo0M S COG4326 Sporulation control protein
CMLFLONI_00871 1.2e-26
CMLFLONI_00872 8.5e-75 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
CMLFLONI_00873 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
CMLFLONI_00875 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CMLFLONI_00876 1.6e-137 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
CMLFLONI_00877 1.2e-169 ssuA M Sulfonate ABC transporter
CMLFLONI_00878 9.4e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CMLFLONI_00879 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
CMLFLONI_00881 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CMLFLONI_00882 4.1e-78 ygaO
CMLFLONI_00883 4.4e-29 K Transcriptional regulator
CMLFLONI_00885 7.9e-114 yhzB S B3/4 domain
CMLFLONI_00886 1.5e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CMLFLONI_00887 1.7e-176 yhbB S Putative amidase domain
CMLFLONI_00888 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
CMLFLONI_00889 1.8e-108 yhbD K Protein of unknown function (DUF4004)
CMLFLONI_00890 2.7e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
CMLFLONI_00891 2.1e-70 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
CMLFLONI_00892 0.0 prkA T Ser protein kinase
CMLFLONI_00893 2.5e-225 yhbH S Belongs to the UPF0229 family
CMLFLONI_00894 2.2e-76 yhbI K DNA-binding transcription factor activity
CMLFLONI_00895 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
CMLFLONI_00896 3.1e-271 yhcA EGP Major facilitator Superfamily
CMLFLONI_00897 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
CMLFLONI_00898 2.8e-37 yhcC
CMLFLONI_00899 7.8e-55
CMLFLONI_00900 6.6e-60 yhcF K Transcriptional regulator
CMLFLONI_00901 1.6e-123 yhcG V ABC transporter, ATP-binding protein
CMLFLONI_00902 2.2e-165 yhcH V ABC transporter, ATP-binding protein
CMLFLONI_00903 9.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CMLFLONI_00904 1e-30 cspB K Cold-shock protein
CMLFLONI_00905 1.2e-149 metQ M Belongs to the nlpA lipoprotein family
CMLFLONI_00906 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
CMLFLONI_00907 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMLFLONI_00908 8.3e-78 S Protein of unknown function (DUF2812)
CMLFLONI_00909 1.2e-49 K Transcriptional regulator PadR-like family
CMLFLONI_00910 4.1e-40 yhcM
CMLFLONI_00911 4.8e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CMLFLONI_00912 4.4e-164 yhcP
CMLFLONI_00913 8.9e-100 yhcQ M Spore coat protein
CMLFLONI_00914 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
CMLFLONI_00915 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
CMLFLONI_00916 3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMLFLONI_00917 9.3e-68 yhcU S Family of unknown function (DUF5365)
CMLFLONI_00918 9.9e-68 yhcV S COG0517 FOG CBS domain
CMLFLONI_00919 1.3e-119 yhcW 5.4.2.6 S hydrolase
CMLFLONI_00920 1.7e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CMLFLONI_00921 1.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CMLFLONI_00922 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
CMLFLONI_00923 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
CMLFLONI_00924 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CMLFLONI_00925 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
CMLFLONI_00926 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
CMLFLONI_00927 8e-213 yhcY 2.7.13.3 T Histidine kinase
CMLFLONI_00928 7.2e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_00929 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
CMLFLONI_00930 1.2e-38 yhdB S YhdB-like protein
CMLFLONI_00931 3.1e-53 yhdC S Protein of unknown function (DUF3889)
CMLFLONI_00932 1.8e-188 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CMLFLONI_00933 6e-76 nsrR K Transcriptional regulator
CMLFLONI_00934 1.3e-237 ygxB M Conserved TM helix
CMLFLONI_00935 6.3e-276 ycgB S Stage V sporulation protein R
CMLFLONI_00936 4.9e-257 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
CMLFLONI_00937 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CMLFLONI_00938 3.8e-162 citR K Transcriptional regulator
CMLFLONI_00939 2.5e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
CMLFLONI_00940 1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_00941 3.8e-249 yhdG E amino acid
CMLFLONI_00942 8.2e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CMLFLONI_00943 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_00944 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_00945 8.1e-45 yhdK S Sigma-M inhibitor protein
CMLFLONI_00946 6.6e-201 yhdL S Sigma factor regulator N-terminal
CMLFLONI_00947 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_00948 1.5e-191 yhdN C Aldo keto reductase
CMLFLONI_00949 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CMLFLONI_00950 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CMLFLONI_00951 4.1e-74 cueR K transcriptional
CMLFLONI_00952 2e-222 yhdR 2.6.1.1 E Aminotransferase
CMLFLONI_00953 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
CMLFLONI_00954 3.2e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMLFLONI_00955 9.6e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CMLFLONI_00956 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMLFLONI_00958 9.9e-184 yhdY M Mechanosensitive ion channel
CMLFLONI_00959 3.8e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
CMLFLONI_00960 4.8e-146 yheN G deacetylase
CMLFLONI_00961 1.8e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
CMLFLONI_00962 1.7e-225 nhaC C Na H antiporter
CMLFLONI_00963 1.7e-83 nhaX T Belongs to the universal stress protein A family
CMLFLONI_00964 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
CMLFLONI_00965 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
CMLFLONI_00966 3.7e-111 yheG GM NAD(P)H-binding
CMLFLONI_00967 6.3e-28 sspB S spore protein
CMLFLONI_00968 1.3e-36 yheE S Family of unknown function (DUF5342)
CMLFLONI_00969 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
CMLFLONI_00970 4.3e-216 yheC HJ YheC/D like ATP-grasp
CMLFLONI_00971 1.4e-201 yheB S Belongs to the UPF0754 family
CMLFLONI_00972 9.5e-48 yheA S Belongs to the UPF0342 family
CMLFLONI_00973 2e-205 yhaZ L DNA alkylation repair enzyme
CMLFLONI_00974 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
CMLFLONI_00975 6.7e-292 hemZ H coproporphyrinogen III oxidase
CMLFLONI_00976 3.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
CMLFLONI_00977 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
CMLFLONI_00979 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
CMLFLONI_00980 1.1e-26 S YhzD-like protein
CMLFLONI_00981 5.7e-166 yhaQ S ABC transporter, ATP-binding protein
CMLFLONI_00982 2.7e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
CMLFLONI_00983 2.8e-224 yhaO L DNA repair exonuclease
CMLFLONI_00984 0.0 yhaN L AAA domain
CMLFLONI_00985 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
CMLFLONI_00986 1.6e-21 yhaL S Sporulation protein YhaL
CMLFLONI_00987 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
CMLFLONI_00988 8.7e-90 yhaK S Putative zincin peptidase
CMLFLONI_00989 1.3e-54 yhaI S Protein of unknown function (DUF1878)
CMLFLONI_00990 1e-113 hpr K Negative regulator of protease production and sporulation
CMLFLONI_00991 8.2e-39 yhaH S YtxH-like protein
CMLFLONI_00992 5.4e-21
CMLFLONI_00993 3.6e-80 trpP S Tryptophan transporter TrpP
CMLFLONI_00994 7.1e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CMLFLONI_00995 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
CMLFLONI_00996 4.6e-137 ecsA V transporter (ATP-binding protein)
CMLFLONI_00997 5.4e-215 ecsB U ABC transporter
CMLFLONI_00998 4.5e-113 ecsC S EcsC protein family
CMLFLONI_00999 7.7e-227 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
CMLFLONI_01000 1.1e-245 yhfA C membrane
CMLFLONI_01001 2.6e-34 1.15.1.2 C Rubrerythrin
CMLFLONI_01002 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
CMLFLONI_01003 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMLFLONI_01004 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
CMLFLONI_01005 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
CMLFLONI_01006 2.2e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
CMLFLONI_01007 5.4e-101 yhgD K Transcriptional regulator
CMLFLONI_01008 1.1e-213 yhgE S YhgE Pip N-terminal domain protein
CMLFLONI_01009 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMLFLONI_01010 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
CMLFLONI_01011 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
CMLFLONI_01012 3.7e-72 3.4.13.21 S ASCH
CMLFLONI_01013 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
CMLFLONI_01014 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
CMLFLONI_01015 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
CMLFLONI_01016 1.2e-109 yhfK GM NmrA-like family
CMLFLONI_01017 5e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CMLFLONI_01018 1.9e-65 yhfM
CMLFLONI_01019 6.9e-237 yhfN 3.4.24.84 O Peptidase M48
CMLFLONI_01020 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
CMLFLONI_01021 1.1e-77 VY92_01935 K acetyltransferase
CMLFLONI_01022 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
CMLFLONI_01023 2.8e-158 yfmC M Periplasmic binding protein
CMLFLONI_01024 3e-107 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
CMLFLONI_01025 4.4e-200 vraB 2.3.1.9 I Belongs to the thiolase family
CMLFLONI_01026 1.5e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
CMLFLONI_01027 5e-91 bioY S BioY family
CMLFLONI_01028 1.7e-182 hemAT NT chemotaxis protein
CMLFLONI_01029 5.7e-299 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
CMLFLONI_01030 4.7e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_01031 1.3e-32 yhzC S IDEAL
CMLFLONI_01032 9.3e-109 comK K Competence transcription factor
CMLFLONI_01033 6.2e-168 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_01034 1.2e-39 yhjA S Excalibur calcium-binding domain
CMLFLONI_01035 5.7e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMLFLONI_01036 6.9e-27 yhjC S Protein of unknown function (DUF3311)
CMLFLONI_01037 6.7e-60 yhjD
CMLFLONI_01038 9.1e-110 yhjE S SNARE associated Golgi protein
CMLFLONI_01039 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
CMLFLONI_01040 5.2e-281 yhjG CH FAD binding domain
CMLFLONI_01041 2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_01044 2.9e-213 glcP G Major Facilitator Superfamily
CMLFLONI_01045 2.7e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
CMLFLONI_01046 3.8e-159 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
CMLFLONI_01047 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
CMLFLONI_01048 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
CMLFLONI_01049 1.9e-201 abrB S membrane
CMLFLONI_01050 9e-215 EGP Transmembrane secretion effector
CMLFLONI_01051 0.0 S Sugar transport-related sRNA regulator N-term
CMLFLONI_01052 2e-36 yhjQ C COG1145 Ferredoxin
CMLFLONI_01053 2.2e-78 yhjR S Rubrerythrin
CMLFLONI_01054 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
CMLFLONI_01055 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
CMLFLONI_01056 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
CMLFLONI_01057 0.0 sbcC L COG0419 ATPase involved in DNA repair
CMLFLONI_01058 1.1e-49 yisB V COG1403 Restriction endonuclease
CMLFLONI_01059 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
CMLFLONI_01060 5.3e-63 gerPE S Spore germination protein GerPE
CMLFLONI_01061 1.1e-23 gerPD S Spore germination protein
CMLFLONI_01062 5.3e-54 gerPC S Spore germination protein
CMLFLONI_01063 4e-34 gerPB S cell differentiation
CMLFLONI_01064 1.9e-33 gerPA S Spore germination protein
CMLFLONI_01065 1.5e-22 yisI S Spo0E like sporulation regulatory protein
CMLFLONI_01066 2.7e-174 cotH M Spore Coat
CMLFLONI_01067 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
CMLFLONI_01068 3e-57 yisL S UPF0344 protein
CMLFLONI_01069 0.0 wprA O Belongs to the peptidase S8 family
CMLFLONI_01070 4.8e-102 yisN S Protein of unknown function (DUF2777)
CMLFLONI_01071 0.0 asnO 6.3.5.4 E Asparagine synthase
CMLFLONI_01072 4.7e-88 yizA S Damage-inducible protein DinB
CMLFLONI_01073 1.3e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
CMLFLONI_01074 8.9e-243 yisQ V Mate efflux family protein
CMLFLONI_01075 1.2e-160 yisR K Transcriptional regulator
CMLFLONI_01076 4.5e-183 purR K helix_turn _helix lactose operon repressor
CMLFLONI_01077 3.7e-193 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
CMLFLONI_01078 1.5e-91 yisT S DinB family
CMLFLONI_01079 2e-106 argO S Lysine exporter protein LysE YggA
CMLFLONI_01080 1.2e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
CMLFLONI_01081 4e-36 mcbG S Pentapeptide repeats (9 copies)
CMLFLONI_01082 1e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CMLFLONI_01083 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
CMLFLONI_01084 1.3e-229 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CMLFLONI_01085 5.1e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CMLFLONI_01086 2e-118 comB 3.1.3.71 H Belongs to the ComB family
CMLFLONI_01087 1.6e-140 yitD 4.4.1.19 S synthase
CMLFLONI_01088 7.2e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMLFLONI_01089 6e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CMLFLONI_01090 2e-228 yitG EGP Major facilitator Superfamily
CMLFLONI_01091 1.8e-153 yitH K Acetyltransferase (GNAT) domain
CMLFLONI_01092 3.7e-73 yjcF S Acetyltransferase (GNAT) domain
CMLFLONI_01093 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
CMLFLONI_01094 3.3e-54 yajQ S Belongs to the UPF0234 family
CMLFLONI_01095 4e-161 cvfB S protein conserved in bacteria
CMLFLONI_01096 8.5e-94
CMLFLONI_01097 3.6e-171
CMLFLONI_01098 1.5e-97 S Sporulation delaying protein SdpA
CMLFLONI_01099 1.5e-58 K Transcriptional regulator PadR-like family
CMLFLONI_01100 5e-94
CMLFLONI_01101 1.4e-44 yitR S Domain of unknown function (DUF3784)
CMLFLONI_01102 7.6e-310 nprB 3.4.24.28 E Peptidase M4
CMLFLONI_01103 8.4e-159 yitS S protein conserved in bacteria
CMLFLONI_01104 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
CMLFLONI_01105 1.9e-72 ipi S Intracellular proteinase inhibitor
CMLFLONI_01106 1.2e-17 S Protein of unknown function (DUF3813)
CMLFLONI_01107 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
CMLFLONI_01108 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
CMLFLONI_01109 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
CMLFLONI_01110 1.5e-22 pilT S Proteolipid membrane potential modulator
CMLFLONI_01111 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
CMLFLONI_01112 1.7e-88 norB G Major Facilitator Superfamily
CMLFLONI_01113 3.5e-199 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
CMLFLONI_01114 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CMLFLONI_01115 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
CMLFLONI_01116 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
CMLFLONI_01117 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMLFLONI_01118 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
CMLFLONI_01119 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
CMLFLONI_01120 9.5e-28 yjzC S YjzC-like protein
CMLFLONI_01121 2.3e-16 yjzD S Protein of unknown function (DUF2929)
CMLFLONI_01122 6.2e-142 yjaU I carboxylic ester hydrolase activity
CMLFLONI_01123 7.3e-103 yjaV
CMLFLONI_01124 1.1e-183 med S Transcriptional activator protein med
CMLFLONI_01125 7.3e-26 comZ S ComZ
CMLFLONI_01126 2.7e-22 yjzB
CMLFLONI_01127 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
CMLFLONI_01128 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMLFLONI_01129 7.8e-151 yjaZ O Zn-dependent protease
CMLFLONI_01130 1.8e-184 appD P Belongs to the ABC transporter superfamily
CMLFLONI_01131 6.5e-187 appF E Belongs to the ABC transporter superfamily
CMLFLONI_01132 1.4e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
CMLFLONI_01133 1.2e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01134 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01135 5.5e-146 yjbA S Belongs to the UPF0736 family
CMLFLONI_01136 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
CMLFLONI_01137 0.0 oppA E ABC transporter substrate-binding protein
CMLFLONI_01138 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01139 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01140 3e-198 oppD P Belongs to the ABC transporter superfamily
CMLFLONI_01141 1.2e-171 oppF E Belongs to the ABC transporter superfamily
CMLFLONI_01142 1.1e-204 yjbB EGP Major Facilitator Superfamily
CMLFLONI_01143 1.4e-71 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_01144 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
CMLFLONI_01145 6e-112 yjbE P Integral membrane protein TerC family
CMLFLONI_01146 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CMLFLONI_01147 6.1e-221 yjbF S Competence protein
CMLFLONI_01148 0.0 pepF E oligoendopeptidase F
CMLFLONI_01149 1.8e-20
CMLFLONI_01150 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CMLFLONI_01151 3.7e-72 yjbI S Bacterial-like globin
CMLFLONI_01152 4.2e-82 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CMLFLONI_01153 1e-99 yjbK S protein conserved in bacteria
CMLFLONI_01154 2.7e-61 yjbL S Belongs to the UPF0738 family
CMLFLONI_01155 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
CMLFLONI_01156 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMLFLONI_01157 7.5e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMLFLONI_01158 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
CMLFLONI_01159 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
CMLFLONI_01160 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CMLFLONI_01161 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
CMLFLONI_01162 3.6e-218 thiO 1.4.3.19 E Glycine oxidase
CMLFLONI_01163 3e-30 thiS H thiamine diphosphate biosynthetic process
CMLFLONI_01164 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
CMLFLONI_01165 2.3e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CMLFLONI_01166 5.4e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CMLFLONI_01167 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
CMLFLONI_01168 1.4e-52 yjbX S Spore coat protein
CMLFLONI_01169 8.9e-83 cotZ S Spore coat protein
CMLFLONI_01170 7.6e-96 cotY S Spore coat protein Z
CMLFLONI_01171 6.4e-77 cotX S Spore Coat Protein X and V domain
CMLFLONI_01172 3e-32 cotW
CMLFLONI_01173 2.3e-55 cotV S Spore Coat Protein X and V domain
CMLFLONI_01174 8.7e-57 yjcA S Protein of unknown function (DUF1360)
CMLFLONI_01177 2.9e-38 spoVIF S Stage VI sporulation protein F
CMLFLONI_01178 0.0 yjcD 3.6.4.12 L DNA helicase
CMLFLONI_01179 1.7e-38
CMLFLONI_01180 1.5e-71 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_01181 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
CMLFLONI_01182 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
CMLFLONI_01183 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMLFLONI_01184 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMLFLONI_01185 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
CMLFLONI_01186 7e-212 yjcL S Protein of unknown function (DUF819)
CMLFLONI_01188 8.7e-18
CMLFLONI_01189 5.4e-32
CMLFLONI_01190 1.1e-30
CMLFLONI_01191 1.2e-242 M nucleic acid phosphodiester bond hydrolysis
CMLFLONI_01192 8.3e-21
CMLFLONI_01195 1.1e-115 S response regulator aspartate phosphatase
CMLFLONI_01196 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
CMLFLONI_01197 9.2e-141 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_01199 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
CMLFLONI_01200 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
CMLFLONI_01201 8.2e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
CMLFLONI_01202 2.2e-48 yjdF S Protein of unknown function (DUF2992)
CMLFLONI_01203 1e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
CMLFLONI_01205 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CMLFLONI_01206 4.2e-29 S Domain of unknown function (DUF4177)
CMLFLONI_01207 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
CMLFLONI_01208 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CMLFLONI_01210 3.2e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
CMLFLONI_01211 6.7e-81 S Protein of unknown function (DUF2690)
CMLFLONI_01212 2.3e-20 yjfB S Putative motility protein
CMLFLONI_01213 4.9e-165 yjfC O Predicted Zn-dependent protease (DUF2268)
CMLFLONI_01214 1.2e-45 T PhoQ Sensor
CMLFLONI_01215 8.9e-104 yjgB S Domain of unknown function (DUF4309)
CMLFLONI_01216 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CMLFLONI_01217 4.3e-146 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CMLFLONI_01218 2.8e-94 yjgD S Protein of unknown function (DUF1641)
CMLFLONI_01219 1.5e-06 S Domain of unknown function (DUF4352)
CMLFLONI_01220 3.8e-116 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
CMLFLONI_01222 2.4e-220 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
CMLFLONI_01223 1.1e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
CMLFLONI_01224 8.2e-30
CMLFLONI_01225 7.3e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CMLFLONI_01226 5.6e-122 ybbM S transport system, permease component
CMLFLONI_01227 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
CMLFLONI_01228 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
CMLFLONI_01229 9.8e-91 yjlB S Cupin domain
CMLFLONI_01230 7.1e-66 yjlC S Protein of unknown function (DUF1641)
CMLFLONI_01231 2.9e-218 yjlD 1.6.99.3 C NADH dehydrogenase
CMLFLONI_01232 4.3e-277 uxaC 5.3.1.12 G glucuronate isomerase
CMLFLONI_01233 6e-247 yjmB G symporter YjmB
CMLFLONI_01234 4.2e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
CMLFLONI_01235 6.5e-190 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
CMLFLONI_01236 5.8e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
CMLFLONI_01237 2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_01238 8.3e-227 exuT G Sugar (and other) transporter
CMLFLONI_01239 2.6e-183 exuR K transcriptional
CMLFLONI_01240 2.1e-282 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
CMLFLONI_01241 8.4e-287 uxaA 4.2.1.7, 4.4.1.24 G Altronate
CMLFLONI_01242 4.3e-130 MA20_18170 S membrane transporter protein
CMLFLONI_01243 2.3e-78 yjoA S DinB family
CMLFLONI_01244 1.1e-244 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
CMLFLONI_01245 1e-212 S response regulator aspartate phosphatase
CMLFLONI_01247 6.3e-41 S YCII-related domain
CMLFLONI_01248 7.2e-167 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
CMLFLONI_01249 2.3e-60 yjqA S Bacterial PH domain
CMLFLONI_01250 3.3e-109 yjqB S Pfam:DUF867
CMLFLONI_01251 4.4e-160 ydbD P Catalase
CMLFLONI_01252 1.6e-111 xkdA E IrrE N-terminal-like domain
CMLFLONI_01253 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
CMLFLONI_01255 5.9e-157 xkdB K sequence-specific DNA binding
CMLFLONI_01256 4.1e-118 xkdC L Bacterial dnaA protein
CMLFLONI_01259 2.3e-09 yqaO S Phage-like element PBSX protein XtrA
CMLFLONI_01260 7e-84 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
CMLFLONI_01261 1.5e-138 xtmA L phage terminase small subunit
CMLFLONI_01262 1.8e-253 xtmB S phage terminase, large subunit
CMLFLONI_01263 1.6e-285 yqbA S portal protein
CMLFLONI_01264 2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CMLFLONI_01265 5.8e-169 xkdG S Phage capsid family
CMLFLONI_01266 5.1e-63 yqbG S Protein of unknown function (DUF3199)
CMLFLONI_01267 2.5e-64 yqbH S Domain of unknown function (DUF3599)
CMLFLONI_01268 2.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
CMLFLONI_01269 1.9e-77 xkdJ
CMLFLONI_01270 2.5e-256 xkdK S Phage tail sheath C-terminal domain
CMLFLONI_01271 6.1e-76 xkdM S Phage tail tube protein
CMLFLONI_01272 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
CMLFLONI_01273 0.0 xkdO L Transglycosylase SLT domain
CMLFLONI_01274 3.7e-122 xkdP S Lysin motif
CMLFLONI_01275 9e-181 yqbQ 3.2.1.96 G NLP P60 protein
CMLFLONI_01276 1e-38 xkdR S Protein of unknown function (DUF2577)
CMLFLONI_01277 9e-69 xkdS S Protein of unknown function (DUF2634)
CMLFLONI_01278 3.3e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CMLFLONI_01279 5.8e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CMLFLONI_01280 8.7e-41
CMLFLONI_01281 0.0
CMLFLONI_01282 1.5e-42 xkdW S XkdW protein
CMLFLONI_01283 2.1e-21 xkdX
CMLFLONI_01284 2.8e-154 xepA
CMLFLONI_01285 2.8e-39 xhlA S Haemolysin XhlA
CMLFLONI_01286 9.3e-40 xhlB S SPP1 phage holin
CMLFLONI_01287 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CMLFLONI_01288 6.7e-23 spoIISB S Stage II sporulation protein SB
CMLFLONI_01289 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
CMLFLONI_01290 7.6e-175 pit P phosphate transporter
CMLFLONI_01291 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
CMLFLONI_01292 6.1e-241 steT E amino acid
CMLFLONI_01293 6.1e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
CMLFLONI_01295 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMLFLONI_01296 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_01297 2.2e-209 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMLFLONI_01298 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
CMLFLONI_01299 5.1e-153 dppA E D-aminopeptidase
CMLFLONI_01300 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01301 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
CMLFLONI_01302 5.6e-186 dppD P Belongs to the ABC transporter superfamily
CMLFLONI_01303 0.0 dppE E ABC transporter substrate-binding protein
CMLFLONI_01305 5.1e-173 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
CMLFLONI_01306 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
CMLFLONI_01307 1.8e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CMLFLONI_01308 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
CMLFLONI_01309 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
CMLFLONI_01310 1.2e-149 ykgA E Amidinotransferase
CMLFLONI_01311 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
CMLFLONI_01312 3.9e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CMLFLONI_01313 1e-07
CMLFLONI_01314 2.7e-129 ykjA S Protein of unknown function (DUF421)
CMLFLONI_01315 3.9e-98 ykkA S Protein of unknown function (DUF664)
CMLFLONI_01316 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CMLFLONI_01317 3.5e-55 ykkC P Multidrug resistance protein
CMLFLONI_01318 7e-50 ykkD P Multidrug resistance protein
CMLFLONI_01319 1.2e-168 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
CMLFLONI_01320 2.2e-199 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMLFLONI_01321 1.8e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
CMLFLONI_01322 4.8e-70 ohrA O Organic hydroperoxide resistance protein
CMLFLONI_01323 3.9e-75 ohrR K COG1846 Transcriptional regulators
CMLFLONI_01324 8.4e-72 ohrB O Organic hydroperoxide resistance protein
CMLFLONI_01326 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
CMLFLONI_01327 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
CMLFLONI_01328 5e-176 isp O Belongs to the peptidase S8 family
CMLFLONI_01329 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CMLFLONI_01330 5.3e-136 ykoC P Cobalt transport protein
CMLFLONI_01331 4.1e-303 P ABC transporter, ATP-binding protein
CMLFLONI_01332 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
CMLFLONI_01333 1.1e-109 ykoF S YKOF-related Family
CMLFLONI_01334 2.7e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_01335 7.5e-242 ykoH 2.7.13.3 T Histidine kinase
CMLFLONI_01336 3.1e-111 ykoI S Peptidase propeptide and YPEB domain
CMLFLONI_01337 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
CMLFLONI_01340 5e-222 mgtE P Acts as a magnesium transporter
CMLFLONI_01341 1.4e-53 tnrA K transcriptional
CMLFLONI_01342 5.9e-18
CMLFLONI_01343 6.9e-26 ykoL
CMLFLONI_01344 1.3e-81 mhqR K transcriptional
CMLFLONI_01345 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
CMLFLONI_01346 3.7e-99 ykoP G polysaccharide deacetylase
CMLFLONI_01347 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
CMLFLONI_01348 0.0 ykoS
CMLFLONI_01349 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_01350 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
CMLFLONI_01351 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
CMLFLONI_01352 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
CMLFLONI_01353 3.5e-109 ykoX S membrane-associated protein
CMLFLONI_01354 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
CMLFLONI_01355 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_01356 4.4e-110 rsgI S Anti-sigma factor N-terminus
CMLFLONI_01357 1.9e-26 sspD S small acid-soluble spore protein
CMLFLONI_01358 1.5e-124 ykrK S Domain of unknown function (DUF1836)
CMLFLONI_01359 3.9e-154 htpX O Belongs to the peptidase M48B family
CMLFLONI_01360 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
CMLFLONI_01361 1.2e-10 ydfR S Protein of unknown function (DUF421)
CMLFLONI_01362 2.2e-19 ykzE
CMLFLONI_01363 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
CMLFLONI_01364 0.0 kinE 2.7.13.3 T Histidine kinase
CMLFLONI_01365 1e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CMLFLONI_01367 3.1e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
CMLFLONI_01368 7e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
CMLFLONI_01369 1.7e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
CMLFLONI_01370 2.6e-230 mtnE 2.6.1.83 E Aminotransferase
CMLFLONI_01371 4.5e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
CMLFLONI_01372 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
CMLFLONI_01373 3.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
CMLFLONI_01374 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
CMLFLONI_01375 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
CMLFLONI_01376 6.4e-09 S Spo0E like sporulation regulatory protein
CMLFLONI_01377 2.6e-63 eag
CMLFLONI_01378 1.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
CMLFLONI_01379 1.3e-75 ykvE K transcriptional
CMLFLONI_01380 2.5e-125 motB N Flagellar motor protein
CMLFLONI_01381 2.7e-138 motA N flagellar motor
CMLFLONI_01382 0.0 clpE O Belongs to the ClpA ClpB family
CMLFLONI_01383 1.4e-179 ykvI S membrane
CMLFLONI_01384 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CMLFLONI_01385 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
CMLFLONI_01386 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
CMLFLONI_01387 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
CMLFLONI_01388 9.3e-59 ykvN K HxlR-like helix-turn-helix
CMLFLONI_01389 2.9e-131 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_01390 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
CMLFLONI_01391 3.5e-35 3.5.1.104 M LysM domain
CMLFLONI_01392 4.2e-132 G Glycosyl hydrolases family 18
CMLFLONI_01393 5.6e-46 ykvR S Protein of unknown function (DUF3219)
CMLFLONI_01394 6e-25 ykvS S protein conserved in bacteria
CMLFLONI_01395 2.8e-28
CMLFLONI_01396 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
CMLFLONI_01397 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_01398 4.9e-90 stoA CO thiol-disulfide
CMLFLONI_01399 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CMLFLONI_01400 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CMLFLONI_01402 1.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
CMLFLONI_01404 7.6e-128 glcT K antiterminator
CMLFLONI_01405 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_01406 2.1e-39 ptsH G phosphocarrier protein HPr
CMLFLONI_01407 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CMLFLONI_01408 7.2e-39 splA S Transcriptional regulator
CMLFLONI_01409 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
CMLFLONI_01410 1.7e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_01411 3.7e-258 mcpC NT chemotaxis protein
CMLFLONI_01412 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
CMLFLONI_01413 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
CMLFLONI_01414 7e-120 ykwD J protein with SCP PR1 domains
CMLFLONI_01415 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
CMLFLONI_01416 0.0 pilS 2.7.13.3 T Histidine kinase
CMLFLONI_01417 1.8e-153 patA 2.6.1.1 E Aminotransferase
CMLFLONI_01418 1.7e-57 patA 2.6.1.1 E Aminotransferase
CMLFLONI_01419 1.3e-15
CMLFLONI_01420 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
CMLFLONI_01421 1.7e-84 ykyB S YkyB-like protein
CMLFLONI_01422 2.8e-238 ykuC EGP Major facilitator Superfamily
CMLFLONI_01423 1.8e-87 ykuD S protein conserved in bacteria
CMLFLONI_01424 1.4e-164 ykuE S Metallophosphoesterase
CMLFLONI_01425 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_01426 4.4e-233 ykuI T Diguanylate phosphodiesterase
CMLFLONI_01427 3.9e-37 ykuJ S protein conserved in bacteria
CMLFLONI_01428 4.4e-94 ykuK S Ribonuclease H-like
CMLFLONI_01429 3.9e-27 ykzF S Antirepressor AbbA
CMLFLONI_01430 1.6e-76 ykuL S CBS domain
CMLFLONI_01431 3.5e-168 ccpC K Transcriptional regulator
CMLFLONI_01432 5.9e-85 fld C Flavodoxin domain
CMLFLONI_01433 2.2e-173 ykuO
CMLFLONI_01434 3.9e-78 fld C Flavodoxin
CMLFLONI_01435 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
CMLFLONI_01436 2.1e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
CMLFLONI_01437 9e-37 ykuS S Belongs to the UPF0180 family
CMLFLONI_01438 8.8e-142 ykuT M Mechanosensitive ion channel
CMLFLONI_01439 3.9e-101 ykuU O Alkyl hydroperoxide reductase
CMLFLONI_01440 6.3e-81 ykuV CO thiol-disulfide
CMLFLONI_01441 5.8e-95 rok K Repressor of ComK
CMLFLONI_01442 8.4e-147 yknT
CMLFLONI_01443 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
CMLFLONI_01444 2.9e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
CMLFLONI_01445 1.7e-243 moeA 2.10.1.1 H molybdopterin
CMLFLONI_01446 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
CMLFLONI_01447 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
CMLFLONI_01448 2.4e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
CMLFLONI_01449 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
CMLFLONI_01450 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
CMLFLONI_01451 9.4e-116 yknW S Yip1 domain
CMLFLONI_01452 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CMLFLONI_01453 7.2e-124 macB V ABC transporter, ATP-binding protein
CMLFLONI_01454 4e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
CMLFLONI_01455 3.1e-136 fruR K Transcriptional regulator
CMLFLONI_01456 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
CMLFLONI_01457 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
CMLFLONI_01458 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CMLFLONI_01459 8.1e-39 ykoA
CMLFLONI_01460 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
CMLFLONI_01461 9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMLFLONI_01462 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
CMLFLONI_01463 1.1e-12 S Uncharacterized protein YkpC
CMLFLONI_01464 7.7e-183 mreB D Rod-share determining protein MreBH
CMLFLONI_01465 1.5e-43 abrB K of stationary sporulation gene expression
CMLFLONI_01466 1e-240 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
CMLFLONI_01467 2.7e-154 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
CMLFLONI_01468 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
CMLFLONI_01469 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CMLFLONI_01470 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMLFLONI_01471 8.2e-31 ykzG S Belongs to the UPF0356 family
CMLFLONI_01472 2.1e-146 ykrA S hydrolases of the HAD superfamily
CMLFLONI_01473 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMLFLONI_01475 1.1e-107 recN L Putative cell-wall binding lipoprotein
CMLFLONI_01476 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CMLFLONI_01477 1.1e-178 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CMLFLONI_01478 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMLFLONI_01479 4.1e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CMLFLONI_01480 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
CMLFLONI_01481 6.5e-276 speA 4.1.1.19 E Arginine
CMLFLONI_01482 1.6e-42 yktA S Belongs to the UPF0223 family
CMLFLONI_01483 2.3e-116 yktB S Belongs to the UPF0637 family
CMLFLONI_01484 7.1e-26 ykzI
CMLFLONI_01485 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
CMLFLONI_01486 5.8e-77 ykzC S Acetyltransferase (GNAT) family
CMLFLONI_01487 4.6e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
CMLFLONI_01488 1.1e-292 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
CMLFLONI_01489 0.0 ylaA
CMLFLONI_01490 2.7e-42 ylaB
CMLFLONI_01491 7.4e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_01492 4.5e-11 sigC S Putative zinc-finger
CMLFLONI_01493 1.8e-38 ylaE
CMLFLONI_01494 8.2e-22 S Family of unknown function (DUF5325)
CMLFLONI_01495 0.0 typA T GTP-binding protein TypA
CMLFLONI_01496 5.6e-47 ylaH S YlaH-like protein
CMLFLONI_01497 2.5e-32 ylaI S protein conserved in bacteria
CMLFLONI_01498 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CMLFLONI_01499 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
CMLFLONI_01500 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
CMLFLONI_01501 3.1e-170 glsA 3.5.1.2 E Belongs to the glutaminase family
CMLFLONI_01502 8.7e-44 ylaN S Belongs to the UPF0358 family
CMLFLONI_01503 2.5e-212 ftsW D Belongs to the SEDS family
CMLFLONI_01504 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
CMLFLONI_01505 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
CMLFLONI_01506 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
CMLFLONI_01507 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
CMLFLONI_01508 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CMLFLONI_01509 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
CMLFLONI_01510 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
CMLFLONI_01511 1.5e-166 ctaG S cytochrome c oxidase
CMLFLONI_01512 7e-62 ylbA S YugN-like family
CMLFLONI_01513 2.6e-74 ylbB T COG0517 FOG CBS domain
CMLFLONI_01514 9.6e-200 ylbC S protein with SCP PR1 domains
CMLFLONI_01515 2.8e-61 ylbD S Putative coat protein
CMLFLONI_01516 6.7e-37 ylbE S YlbE-like protein
CMLFLONI_01517 1.8e-75 ylbF S Belongs to the UPF0342 family
CMLFLONI_01518 7.5e-39 ylbG S UPF0298 protein
CMLFLONI_01519 5.4e-98 rsmD 2.1.1.171 L Methyltransferase
CMLFLONI_01520 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
CMLFLONI_01521 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
CMLFLONI_01522 2.2e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
CMLFLONI_01523 6.8e-187 ylbL T Belongs to the peptidase S16 family
CMLFLONI_01524 3.3e-228 ylbM S Belongs to the UPF0348 family
CMLFLONI_01526 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
CMLFLONI_01527 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
CMLFLONI_01528 3.4e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
CMLFLONI_01529 4e-89 ylbP K n-acetyltransferase
CMLFLONI_01530 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CMLFLONI_01531 4e-303 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
CMLFLONI_01532 2.9e-78 mraZ K Belongs to the MraZ family
CMLFLONI_01533 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
CMLFLONI_01534 3.7e-44 ftsL D Essential cell division protein
CMLFLONI_01535 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
CMLFLONI_01536 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
CMLFLONI_01537 5.8e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CMLFLONI_01538 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CMLFLONI_01539 7.7e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
CMLFLONI_01540 5.7e-186 spoVE D Belongs to the SEDS family
CMLFLONI_01541 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
CMLFLONI_01542 5.3e-167 murB 1.3.1.98 M cell wall formation
CMLFLONI_01543 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
CMLFLONI_01544 2.4e-103 ylxW S protein conserved in bacteria
CMLFLONI_01545 1.8e-91 ylxX S protein conserved in bacteria
CMLFLONI_01546 6.2e-58 sbp S small basic protein
CMLFLONI_01547 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
CMLFLONI_01548 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CMLFLONI_01549 0.0 bpr O COG1404 Subtilisin-like serine proteases
CMLFLONI_01550 1.7e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
CMLFLONI_01551 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_01552 4e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_01553 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
CMLFLONI_01554 1e-253 argE 3.5.1.16 E Acetylornithine deacetylase
CMLFLONI_01555 2.4e-37 ylmC S sporulation protein
CMLFLONI_01556 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
CMLFLONI_01557 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CMLFLONI_01558 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
CMLFLONI_01559 1.3e-39 yggT S membrane
CMLFLONI_01560 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
CMLFLONI_01561 2.6e-67 divIVA D Cell division initiation protein
CMLFLONI_01562 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CMLFLONI_01563 3.2e-62 dksA T COG1734 DnaK suppressor protein
CMLFLONI_01564 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
CMLFLONI_01565 4.2e-164 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
CMLFLONI_01566 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
CMLFLONI_01567 5.4e-229 pyrP F Xanthine uracil
CMLFLONI_01568 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
CMLFLONI_01569 1.4e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
CMLFLONI_01570 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
CMLFLONI_01571 0.0 carB 6.3.5.5 F Belongs to the CarB family
CMLFLONI_01572 6.5e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
CMLFLONI_01573 1e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
CMLFLONI_01574 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
CMLFLONI_01575 4.7e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
CMLFLONI_01577 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
CMLFLONI_01578 1.8e-179 cysP P phosphate transporter
CMLFLONI_01579 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
CMLFLONI_01580 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
CMLFLONI_01581 4.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
CMLFLONI_01582 1.4e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
CMLFLONI_01583 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
CMLFLONI_01584 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
CMLFLONI_01585 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
CMLFLONI_01586 2.4e-156 yloC S stress-induced protein
CMLFLONI_01587 1.5e-40 ylzA S Belongs to the UPF0296 family
CMLFLONI_01588 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
CMLFLONI_01589 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
CMLFLONI_01590 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CMLFLONI_01591 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CMLFLONI_01592 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
CMLFLONI_01593 9.4e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
CMLFLONI_01594 6e-252 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
CMLFLONI_01595 9e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CMLFLONI_01596 7.9e-140 stp 3.1.3.16 T phosphatase
CMLFLONI_01597 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
CMLFLONI_01598 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
CMLFLONI_01599 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
CMLFLONI_01600 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
CMLFLONI_01601 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
CMLFLONI_01602 5.5e-59 asp S protein conserved in bacteria
CMLFLONI_01603 2.3e-301 yloV S kinase related to dihydroxyacetone kinase
CMLFLONI_01604 9.6e-118 sdaAB 4.3.1.17 E L-serine dehydratase
CMLFLONI_01605 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
CMLFLONI_01606 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CMLFLONI_01607 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
CMLFLONI_01608 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
CMLFLONI_01609 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CMLFLONI_01610 6.1e-129 IQ reductase
CMLFLONI_01611 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
CMLFLONI_01612 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
CMLFLONI_01613 0.0 smc D Required for chromosome condensation and partitioning
CMLFLONI_01614 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CMLFLONI_01615 2.9e-87
CMLFLONI_01616 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
CMLFLONI_01617 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CMLFLONI_01618 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
CMLFLONI_01619 3.8e-35 ylqC S Belongs to the UPF0109 family
CMLFLONI_01620 6.3e-61 ylqD S YlqD protein
CMLFLONI_01621 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CMLFLONI_01622 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
CMLFLONI_01623 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
CMLFLONI_01624 7.9e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
CMLFLONI_01625 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMLFLONI_01626 1.8e-288 ylqG
CMLFLONI_01627 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
CMLFLONI_01628 1.3e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
CMLFLONI_01629 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
CMLFLONI_01630 4.7e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
CMLFLONI_01631 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CMLFLONI_01632 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
CMLFLONI_01633 2.5e-169 xerC L tyrosine recombinase XerC
CMLFLONI_01634 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
CMLFLONI_01635 8.5e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
CMLFLONI_01636 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CMLFLONI_01637 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
CMLFLONI_01638 3.4e-74 flgC N Belongs to the flagella basal body rod proteins family
CMLFLONI_01639 1.9e-31 fliE N Flagellar hook-basal body
CMLFLONI_01640 7e-255 fliF N The M ring may be actively involved in energy transduction
CMLFLONI_01641 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CMLFLONI_01642 2.2e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
CMLFLONI_01643 2.3e-240 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
CMLFLONI_01644 1.5e-69 fliJ N Flagellar biosynthesis chaperone
CMLFLONI_01645 5.5e-35 ylxF S MgtE intracellular N domain
CMLFLONI_01646 2.5e-195 fliK N Flagellar hook-length control protein
CMLFLONI_01647 1.7e-72 flgD N Flagellar basal body rod modification protein
CMLFLONI_01648 8.2e-140 flgG N Flagellar basal body rod
CMLFLONI_01649 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
CMLFLONI_01650 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
CMLFLONI_01651 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
CMLFLONI_01652 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
CMLFLONI_01653 2.2e-75 fliZ N Flagellar biosynthesis protein, FliO
CMLFLONI_01654 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
CMLFLONI_01655 2.2e-36 fliQ N Role in flagellar biosynthesis
CMLFLONI_01656 3.6e-132 fliR N Flagellar biosynthetic protein FliR
CMLFLONI_01657 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMLFLONI_01658 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
CMLFLONI_01659 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
CMLFLONI_01660 2.8e-157 flhG D Belongs to the ParA family
CMLFLONI_01661 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
CMLFLONI_01662 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
CMLFLONI_01663 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
CMLFLONI_01664 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
CMLFLONI_01665 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
CMLFLONI_01666 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_01667 4.8e-77 ylxL
CMLFLONI_01668 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
CMLFLONI_01669 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
CMLFLONI_01670 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
CMLFLONI_01671 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
CMLFLONI_01672 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CMLFLONI_01673 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
CMLFLONI_01674 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
CMLFLONI_01675 2.9e-224 rasP M zinc metalloprotease
CMLFLONI_01676 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
CMLFLONI_01677 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CMLFLONI_01679 4.7e-138 spaB S Lantibiotic dehydratase, C terminus
CMLFLONI_01680 6.9e-102 spaT V ABC transporter
CMLFLONI_01681 1.3e-51 spaC2 V PFAM Lanthionine synthetase
CMLFLONI_01682 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
CMLFLONI_01683 1.1e-203 nusA K Participates in both transcription termination and antitermination
CMLFLONI_01684 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
CMLFLONI_01685 3.1e-47 ylxQ J ribosomal protein
CMLFLONI_01686 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
CMLFLONI_01687 3.9e-44 ylxP S protein conserved in bacteria
CMLFLONI_01688 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
CMLFLONI_01689 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CMLFLONI_01690 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
CMLFLONI_01691 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
CMLFLONI_01692 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
CMLFLONI_01693 2.6e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
CMLFLONI_01694 2.2e-232 pepR S Belongs to the peptidase M16 family
CMLFLONI_01695 2.6e-42 ymxH S YlmC YmxH family
CMLFLONI_01696 1.1e-161 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
CMLFLONI_01697 1.1e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
CMLFLONI_01698 1.9e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
CMLFLONI_01699 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CMLFLONI_01700 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CMLFLONI_01701 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CMLFLONI_01702 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
CMLFLONI_01703 4.4e-32 S YlzJ-like protein
CMLFLONI_01704 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
CMLFLONI_01705 1.4e-133 ymfC K Transcriptional regulator
CMLFLONI_01706 3.8e-205 ymfD EGP Major facilitator Superfamily
CMLFLONI_01707 7e-234 ymfF S Peptidase M16
CMLFLONI_01708 5.1e-240 ymfH S zinc protease
CMLFLONI_01709 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
CMLFLONI_01710 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
CMLFLONI_01711 2.7e-143 ymfK S Protein of unknown function (DUF3388)
CMLFLONI_01712 1.9e-124 ymfM S protein conserved in bacteria
CMLFLONI_01713 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CMLFLONI_01714 4.8e-235 cinA 3.5.1.42 S Belongs to the CinA family
CMLFLONI_01715 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
CMLFLONI_01716 2.6e-211 pbpX V Beta-lactamase
CMLFLONI_01717 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
CMLFLONI_01718 1.9e-152 ymdB S protein conserved in bacteria
CMLFLONI_01719 1.2e-36 spoVS S Stage V sporulation protein S
CMLFLONI_01720 4.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
CMLFLONI_01721 1.2e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CMLFLONI_01722 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
CMLFLONI_01723 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
CMLFLONI_01724 2.2e-88 cotE S Spore coat protein
CMLFLONI_01725 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
CMLFLONI_01726 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CMLFLONI_01727 2e-69 S Regulatory protein YrvL
CMLFLONI_01728 1.8e-96 ymcC S Membrane
CMLFLONI_01729 2.2e-108 pksA K Transcriptional regulator
CMLFLONI_01730 2.4e-124 pksB 3.1.2.6 S Polyketide biosynthesis
CMLFLONI_01731 1.2e-160 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CMLFLONI_01733 1.6e-182 pksD Q Acyl transferase domain
CMLFLONI_01734 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
CMLFLONI_01735 1.8e-37 acpK IQ Phosphopantetheine attachment site
CMLFLONI_01736 1.7e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
CMLFLONI_01737 8.7e-245 pksG 2.3.3.10 I synthase
CMLFLONI_01738 1.3e-142 pksH 4.2.1.18 I enoyl-CoA hydratase
CMLFLONI_01739 2.6e-135 pksI I Belongs to the enoyl-CoA hydratase isomerase family
CMLFLONI_01740 0.0 rhiB IQ polyketide synthase
CMLFLONI_01741 0.0 pfaA Q Polyketide synthase of type I
CMLFLONI_01742 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
CMLFLONI_01743 0.0 dhbF IQ polyketide synthase
CMLFLONI_01744 0.0 pks13 HQ Beta-ketoacyl synthase
CMLFLONI_01745 1.3e-229 cypA C Cytochrome P450
CMLFLONI_01746 4.9e-60 ymzB
CMLFLONI_01747 2e-160 ymaE S Metallo-beta-lactamase superfamily
CMLFLONI_01748 6.6e-251 aprX O Belongs to the peptidase S8 family
CMLFLONI_01749 1.9e-07 K Transcriptional regulator
CMLFLONI_01750 1.3e-125 ymaC S Replication protein
CMLFLONI_01751 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
CMLFLONI_01752 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
CMLFLONI_01753 5.4e-50 ebrA P Small Multidrug Resistance protein
CMLFLONI_01755 2.1e-46 ymaF S YmaF family
CMLFLONI_01756 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
CMLFLONI_01757 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
CMLFLONI_01758 8.2e-23
CMLFLONI_01759 4.5e-22 ymzA
CMLFLONI_01760 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
CMLFLONI_01761 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01762 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01763 2e-109 ymaB
CMLFLONI_01764 1.1e-112 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CMLFLONI_01765 2.4e-97 spoVK O stage V sporulation protein K
CMLFLONI_01767 5.8e-81 yhbS S family acetyltransferase
CMLFLONI_01768 1.9e-108 yokF 3.1.31.1 L RNA catabolic process
CMLFLONI_01769 7.6e-65 G SMI1-KNR4 cell-wall
CMLFLONI_01770 1.7e-172 yobL S Bacterial EndoU nuclease
CMLFLONI_01771 8.2e-76 S SMI1-KNR4 cell-wall
CMLFLONI_01772 1.8e-91 yokK S SMI1 / KNR4 family
CMLFLONI_01773 6.8e-100 S aspartate phosphatase
CMLFLONI_01777 8.4e-54 S YolD-like protein
CMLFLONI_01778 1.5e-233 S impB/mucB/samB family C-terminal domain
CMLFLONI_01780 0.0 V Peptidase C39 family
CMLFLONI_01781 1.2e-70 CO cell redox homeostasis
CMLFLONI_01782 2.9e-240 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_01783 3.4e-74 O protein disulfide oxidoreductase activity
CMLFLONI_01784 5.5e-40 S SPP1 phage holin
CMLFLONI_01785 4.4e-32 bhlA S BhlA holin family
CMLFLONI_01786 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CMLFLONI_01787 0.0 G Exopolysaccharide biosynthesis protein
CMLFLONI_01788 4.9e-135
CMLFLONI_01789 4.9e-298 S Pfam Transposase IS66
CMLFLONI_01790 4.2e-82 S Phage tail protein
CMLFLONI_01791 0.0 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CMLFLONI_01792 1.4e-108
CMLFLONI_01793 3.2e-17
CMLFLONI_01796 3.7e-190 xerH A Belongs to the 'phage' integrase family
CMLFLONI_01797 8.7e-56
CMLFLONI_01798 1.2e-56
CMLFLONI_01799 1.5e-10 xkdX
CMLFLONI_01800 8.1e-07
CMLFLONI_01801 3.7e-168
CMLFLONI_01802 6.7e-57
CMLFLONI_01805 2.3e-89
CMLFLONI_01806 8.1e-131
CMLFLONI_01807 2.6e-91
CMLFLONI_01808 1.4e-121
CMLFLONI_01810 1.1e-68
CMLFLONI_01811 1.1e-80
CMLFLONI_01812 1.3e-185
CMLFLONI_01813 5.1e-93
CMLFLONI_01814 3.4e-261
CMLFLONI_01815 5e-279
CMLFLONI_01816 0.0 gp17a S Terminase-like family
CMLFLONI_01817 1.8e-175
CMLFLONI_01821 1.3e-197 S Calcineurin-like phosphoesterase superfamily domain
CMLFLONI_01824 4.2e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMLFLONI_01825 0.0
CMLFLONI_01828 2.1e-203
CMLFLONI_01833 2.5e-08 S Uncharacterised protein family (UPF0715)
CMLFLONI_01834 1.1e-60
CMLFLONI_01837 2.1e-110
CMLFLONI_01838 5.1e-16
CMLFLONI_01839 1.5e-105
CMLFLONI_01844 2.2e-196 L Belongs to the 'phage' integrase family
CMLFLONI_01845 6e-263 S DNA-sulfur modification-associated
CMLFLONI_01846 2.1e-177
CMLFLONI_01847 1.1e-33 K Transcriptional regulator
CMLFLONI_01851 1.9e-20
CMLFLONI_01856 1.2e-65
CMLFLONI_01861 8.2e-24
CMLFLONI_01867 4.1e-147 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
CMLFLONI_01868 7.5e-126 yoqW S Belongs to the SOS response-associated peptidase family
CMLFLONI_01870 2.7e-187
CMLFLONI_01872 2.2e-143 S Pfam:DUF867
CMLFLONI_01873 0.0 M Parallel beta-helix repeats
CMLFLONI_01877 1.6e-155
CMLFLONI_01878 7.6e-180 L AAA domain
CMLFLONI_01879 2.6e-85
CMLFLONI_01880 5.1e-284 3.6.4.12 J DnaB-like helicase C terminal domain
CMLFLONI_01881 1e-220 L DNA primase activity
CMLFLONI_01882 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CMLFLONI_01883 0.0 S Bacterial DNA polymerase III alpha subunit
CMLFLONI_01884 1.5e-100 DR0488 S protein conserved in bacteria
CMLFLONI_01889 6e-80 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
CMLFLONI_01892 2.3e-147 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
CMLFLONI_01897 2.7e-25 S hydrolase activity
CMLFLONI_01908 5.5e-60 S NrdI Flavodoxin like
CMLFLONI_01909 1.8e-114 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01910 5.5e-196 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01912 1.7e-31 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01913 5.3e-69 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01914 4.5e-86 L HNH endonuclease
CMLFLONI_01915 1.2e-61 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CMLFLONI_01916 2.2e-35 O Glutaredoxin
CMLFLONI_01917 1.1e-09
CMLFLONI_01918 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CMLFLONI_01923 1.5e-160 S Thymidylate synthase
CMLFLONI_01924 5.4e-31 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMLFLONI_01926 7e-36
CMLFLONI_01929 1.4e-28 sspB S spore protein
CMLFLONI_01930 9.7e-160 S Calcineurin-like phosphoesterase
CMLFLONI_01939 4.1e-10 K Cro/C1-type HTH DNA-binding domain
CMLFLONI_01940 1.1e-93 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMLFLONI_01942 3.4e-244 cisA2 L Recombinase
CMLFLONI_01943 8.7e-69 spoVK O stage V sporulation protein K
CMLFLONI_01944 6.7e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CMLFLONI_01945 1.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
CMLFLONI_01946 9.6e-68 glnR K transcriptional
CMLFLONI_01947 7e-261 glnA 6.3.1.2 E glutamine synthetase
CMLFLONI_01948 3.8e-10
CMLFLONI_01949 5.6e-30
CMLFLONI_01950 8.5e-124
CMLFLONI_01951 2.1e-36
CMLFLONI_01952 1.7e-93 G SMI1-KNR4 cell-wall
CMLFLONI_01953 3.6e-96 ynaD J Acetyltransferase (GNAT) domain
CMLFLONI_01954 8.1e-122 ynaE S Domain of unknown function (DUF3885)
CMLFLONI_01955 1.3e-56 ynaF
CMLFLONI_01957 2.3e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
CMLFLONI_01958 1.1e-253 xynT G MFS/sugar transport protein
CMLFLONI_01959 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
CMLFLONI_01960 3.1e-212 xylR GK ROK family
CMLFLONI_01961 3.2e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
CMLFLONI_01962 3.3e-291 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
CMLFLONI_01963 1.1e-110 yokF 3.1.31.1 L RNA catabolic process
CMLFLONI_01964 2e-253 iolT EGP Major facilitator Superfamily
CMLFLONI_01965 1.7e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CMLFLONI_01967 2e-82 yncE S Protein of unknown function (DUF2691)
CMLFLONI_01968 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
CMLFLONI_01971 9.4e-149 S Thymidylate synthase
CMLFLONI_01972 5e-26 S Thymidylate synthase
CMLFLONI_01974 6.6e-131 S Domain of unknown function, YrpD
CMLFLONI_01977 7.9e-25 tatA U protein secretion
CMLFLONI_01978 1.8e-71
CMLFLONI_01979 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
CMLFLONI_01982 8.2e-285 gerAA EG Spore germination protein
CMLFLONI_01983 2.3e-193 gerAB U Spore germination
CMLFLONI_01984 9.4e-220 gerLC S Spore germination protein
CMLFLONI_01985 7.7e-154 yndG S DoxX-like family
CMLFLONI_01986 2.6e-117 yndH S Domain of unknown function (DUF4166)
CMLFLONI_01987 0.0 yndJ S YndJ-like protein
CMLFLONI_01989 5.6e-138 yndL S Replication protein
CMLFLONI_01990 5.8e-74 yndM S Protein of unknown function (DUF2512)
CMLFLONI_01991 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
CMLFLONI_01993 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CMLFLONI_01994 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
CMLFLONI_01995 2.9e-111 yneB L resolvase
CMLFLONI_01996 1.3e-32 ynzC S UPF0291 protein
CMLFLONI_01997 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CMLFLONI_01998 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
CMLFLONI_01999 1.8e-28 yneF S UPF0154 protein
CMLFLONI_02000 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
CMLFLONI_02001 2.3e-125 ccdA O cytochrome c biogenesis protein
CMLFLONI_02002 1.2e-58 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
CMLFLONI_02003 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
CMLFLONI_02004 4.2e-74 yneK S Protein of unknown function (DUF2621)
CMLFLONI_02005 2.2e-63 hspX O Spore coat protein
CMLFLONI_02006 3.9e-19 sspP S Belongs to the SspP family
CMLFLONI_02007 2.5e-14 sspO S Belongs to the SspO family
CMLFLONI_02008 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CMLFLONI_02009 1e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CMLFLONI_02011 3.1e-08 sspN S Small acid-soluble spore protein N family
CMLFLONI_02012 3.9e-35 tlp S Belongs to the Tlp family
CMLFLONI_02013 1.2e-73 yneP S Thioesterase-like superfamily
CMLFLONI_02014 2.2e-53 yneQ
CMLFLONI_02015 4.1e-49 yneR S Belongs to the HesB IscA family
CMLFLONI_02016 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
CMLFLONI_02017 6.6e-69 yccU S CoA-binding protein
CMLFLONI_02018 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMLFLONI_02019 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
CMLFLONI_02020 2.3e-12
CMLFLONI_02021 1.3e-57 ynfC
CMLFLONI_02022 1.2e-250 agcS E Sodium alanine symporter
CMLFLONI_02023 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
CMLFLONI_02025 1.8e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
CMLFLONI_02026 9.5e-294 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
CMLFLONI_02027 4.5e-79 yngA S membrane
CMLFLONI_02028 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMLFLONI_02029 5.5e-104 yngC S membrane-associated protein
CMLFLONI_02030 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
CMLFLONI_02031 7.7e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CMLFLONI_02032 9.2e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CMLFLONI_02033 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
CMLFLONI_02034 8.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
CMLFLONI_02035 1.8e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
CMLFLONI_02036 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CMLFLONI_02037 2.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
CMLFLONI_02038 1.5e-302 yngK T Glycosyl hydrolase-like 10
CMLFLONI_02039 3.1e-63 yngL S Protein of unknown function (DUF1360)
CMLFLONI_02040 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
CMLFLONI_02041 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_02042 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_02043 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_02044 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_02045 1.7e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
CMLFLONI_02046 4.2e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
CMLFLONI_02047 2.3e-246 yoeA V MATE efflux family protein
CMLFLONI_02048 4.1e-98 yoeB S IseA DL-endopeptidase inhibitor
CMLFLONI_02050 2.2e-96 L Integrase
CMLFLONI_02051 5.1e-34 yoeD G Helix-turn-helix domain
CMLFLONI_02052 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CMLFLONI_02053 6.3e-154 gltR1 K Transcriptional regulator
CMLFLONI_02054 3e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
CMLFLONI_02055 5e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
CMLFLONI_02056 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
CMLFLONI_02057 7.8e-155 gltC K Transcriptional regulator
CMLFLONI_02058 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
CMLFLONI_02059 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMLFLONI_02060 2.5e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
CMLFLONI_02061 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_02062 1.6e-38 yoxC S Bacterial protein of unknown function (DUF948)
CMLFLONI_02063 8e-132 yoxB
CMLFLONI_02064 2.9e-96 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
CMLFLONI_02065 1.1e-125 V ABC-2 family transporter protein
CMLFLONI_02066 6.4e-94 V ABC-2 family transporter protein
CMLFLONI_02067 4.8e-139 V AAA domain, putative AbiEii toxin, Type IV TA system
CMLFLONI_02068 6.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_02069 1.5e-233 yoaB EGP Major facilitator Superfamily
CMLFLONI_02070 1e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
CMLFLONI_02071 2.9e-182 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMLFLONI_02072 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CMLFLONI_02073 1.9e-33 yoaF
CMLFLONI_02074 1.7e-08 ywlA S Uncharacterised protein family (UPF0715)
CMLFLONI_02075 7e-14
CMLFLONI_02076 1.5e-38 S Protein of unknown function (DUF4025)
CMLFLONI_02077 2e-183 mcpU NT methyl-accepting chemotaxis protein
CMLFLONI_02078 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
CMLFLONI_02079 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
CMLFLONI_02080 2.3e-111 yoaK S Membrane
CMLFLONI_02081 5.2e-195 pelB 4.2.2.10, 4.2.2.2 G Amb_all
CMLFLONI_02082 4.6e-131 yoqW S Belongs to the SOS response-associated peptidase family
CMLFLONI_02085 2.1e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
CMLFLONI_02087 3.9e-18 yoaP 3.1.3.18 K YoaP-like
CMLFLONI_02089 5e-87
CMLFLONI_02090 7.1e-172 yoaR V vancomycin resistance protein
CMLFLONI_02091 7.3e-75 yoaS S Protein of unknown function (DUF2975)
CMLFLONI_02092 4.4e-30 yozG K Transcriptional regulator
CMLFLONI_02093 4.8e-148 yoaT S Protein of unknown function (DUF817)
CMLFLONI_02094 8.6e-159 yoaU K LysR substrate binding domain
CMLFLONI_02095 1.8e-159 yijE EG EamA-like transporter family
CMLFLONI_02096 1.8e-77 yoaW
CMLFLONI_02097 7.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
CMLFLONI_02098 2.2e-168 bla 3.5.2.6 V beta-lactamase
CMLFLONI_02101 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
CMLFLONI_02102 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
CMLFLONI_02103 8.8e-37 S TM2 domain
CMLFLONI_02107 1.1e-116
CMLFLONI_02109 8.9e-65 yoaQ S Evidence 4 Homologs of previously reported genes of
CMLFLONI_02110 1.8e-33 yoqW S Belongs to the SOS response-associated peptidase family
CMLFLONI_02112 4e-100 S aspartate phosphatase
CMLFLONI_02114 6.9e-19
CMLFLONI_02115 3.3e-28 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMLFLONI_02116 1.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
CMLFLONI_02117 1.2e-100 yokH G SMI1 / KNR4 family
CMLFLONI_02118 2.2e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
CMLFLONI_02119 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
CMLFLONI_02120 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
CMLFLONI_02121 2.5e-143 yobR 2.3.1.1 J FR47-like protein
CMLFLONI_02122 3e-99 yobS K Transcriptional regulator
CMLFLONI_02123 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
CMLFLONI_02124 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
CMLFLONI_02125 9e-178 yobV K WYL domain
CMLFLONI_02126 1e-93 yobW
CMLFLONI_02127 1e-51 czrA K transcriptional
CMLFLONI_02128 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
CMLFLONI_02129 1.5e-92 yozB S membrane
CMLFLONI_02130 2.2e-145
CMLFLONI_02131 1.9e-94 yocC
CMLFLONI_02132 6.9e-189 yocD 3.4.17.13 V peptidase S66
CMLFLONI_02133 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
CMLFLONI_02134 3.2e-198 desK 2.7.13.3 T Histidine kinase
CMLFLONI_02135 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_02136 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
CMLFLONI_02137 0.0 recQ 3.6.4.12 L DNA helicase
CMLFLONI_02138 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMLFLONI_02139 7.4e-83 dksA T general stress protein
CMLFLONI_02140 8.4e-54 yocL
CMLFLONI_02141 2e-30
CMLFLONI_02142 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
CMLFLONI_02143 1.1e-40 yozN
CMLFLONI_02144 1.9e-36 yocN
CMLFLONI_02145 4.2e-56 yozO S Bacterial PH domain
CMLFLONI_02146 2.7e-31 yozC
CMLFLONI_02147 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
CMLFLONI_02148 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
CMLFLONI_02149 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
CMLFLONI_02150 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
CMLFLONI_02151 5.1e-168 yocS S -transporter
CMLFLONI_02152 5.3e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
CMLFLONI_02153 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
CMLFLONI_02154 0.0 yojO P Von Willebrand factor
CMLFLONI_02155 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
CMLFLONI_02156 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CMLFLONI_02157 2.5e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
CMLFLONI_02158 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
CMLFLONI_02159 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
CMLFLONI_02161 4.2e-245 norM V Multidrug efflux pump
CMLFLONI_02162 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CMLFLONI_02163 2.1e-125 yojG S deacetylase
CMLFLONI_02164 1.1e-59 yojF S Protein of unknown function (DUF1806)
CMLFLONI_02165 1.5e-43
CMLFLONI_02166 6.6e-162 rarD S -transporter
CMLFLONI_02167 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
CMLFLONI_02168 3.4e-09
CMLFLONI_02169 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
CMLFLONI_02170 4.7e-64 yodA S tautomerase
CMLFLONI_02171 4.4e-55 yodB K transcriptional
CMLFLONI_02172 1.4e-107 yodC C nitroreductase
CMLFLONI_02173 4.6e-111 mhqD S Carboxylesterase
CMLFLONI_02174 5.5e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
CMLFLONI_02175 6.2e-28 S Protein of unknown function (DUF3311)
CMLFLONI_02176 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMLFLONI_02177 9.7e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
CMLFLONI_02178 6.3e-128 yodH Q Methyltransferase
CMLFLONI_02179 1.5e-23 yodI
CMLFLONI_02180 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
CMLFLONI_02181 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
CMLFLONI_02182 5.3e-09
CMLFLONI_02183 1.4e-53 yodL S YodL-like
CMLFLONI_02184 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
CMLFLONI_02185 2.8e-24 yozD S YozD-like protein
CMLFLONI_02187 6e-123 yodN
CMLFLONI_02188 1.4e-36 yozE S Belongs to the UPF0346 family
CMLFLONI_02189 2.9e-47 yokU S YokU-like protein, putative antitoxin
CMLFLONI_02190 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
CMLFLONI_02191 5.1e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
CMLFLONI_02192 3.2e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
CMLFLONI_02193 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CMLFLONI_02194 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CMLFLONI_02195 1.3e-246 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CMLFLONI_02197 5.9e-143 yiiD K acetyltransferase
CMLFLONI_02198 4.7e-254 cgeD M maturation of the outermost layer of the spore
CMLFLONI_02199 3.1e-63 cgeA
CMLFLONI_02200 2.4e-178 cgeB S Spore maturation protein
CMLFLONI_02201 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
CMLFLONI_02202 7.4e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
CMLFLONI_02203 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
CMLFLONI_02204 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CMLFLONI_02205 1.6e-70 ypoP K transcriptional
CMLFLONI_02206 4.5e-223 mepA V MATE efflux family protein
CMLFLONI_02207 5.5e-29 ypmT S Uncharacterized ympT
CMLFLONI_02208 8.5e-99 ypmS S protein conserved in bacteria
CMLFLONI_02209 4.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
CMLFLONI_02210 1.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
CMLFLONI_02211 3.1e-40 ypmP S Protein of unknown function (DUF2535)
CMLFLONI_02212 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CMLFLONI_02213 1e-184 pspF K Transcriptional regulator
CMLFLONI_02214 4.2e-110 hlyIII S protein, Hemolysin III
CMLFLONI_02215 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
CMLFLONI_02216 1.6e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CMLFLONI_02217 7.6e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
CMLFLONI_02218 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CMLFLONI_02219 8.6e-113 ypjP S YpjP-like protein
CMLFLONI_02220 1.3e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
CMLFLONI_02221 1.7e-75 yphP S Belongs to the UPF0403 family
CMLFLONI_02222 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
CMLFLONI_02223 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
CMLFLONI_02224 6e-106 ypgQ S phosphohydrolase
CMLFLONI_02225 1.3e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
CMLFLONI_02226 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CMLFLONI_02227 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
CMLFLONI_02228 7.9e-31 cspD K Cold-shock protein
CMLFLONI_02229 3.8e-16 degR
CMLFLONI_02230 8.1e-31 S Protein of unknown function (DUF2564)
CMLFLONI_02231 3e-29 ypeQ S Zinc-finger
CMLFLONI_02232 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
CMLFLONI_02233 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
CMLFLONI_02234 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
CMLFLONI_02236 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
CMLFLONI_02237 2e-07
CMLFLONI_02238 1e-38 ypbS S Protein of unknown function (DUF2533)
CMLFLONI_02239 0.0 ypbR S Dynamin family
CMLFLONI_02240 5.1e-87 ypbQ S protein conserved in bacteria
CMLFLONI_02241 1.5e-205 bcsA Q Naringenin-chalcone synthase
CMLFLONI_02242 1.5e-226 pbuX F xanthine
CMLFLONI_02243 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
CMLFLONI_02244 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
CMLFLONI_02245 1.5e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
CMLFLONI_02246 2.7e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
CMLFLONI_02247 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
CMLFLONI_02248 4.1e-184 ptxS K transcriptional
CMLFLONI_02249 2e-157 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
CMLFLONI_02250 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_02251 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
CMLFLONI_02253 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
CMLFLONI_02254 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
CMLFLONI_02255 6.3e-91 ypsA S Belongs to the UPF0398 family
CMLFLONI_02256 5.6e-236 yprB L RNase_H superfamily
CMLFLONI_02257 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
CMLFLONI_02258 5.5e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
CMLFLONI_02259 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
CMLFLONI_02260 1.2e-48 yppG S YppG-like protein
CMLFLONI_02262 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
CMLFLONI_02265 1.3e-187 yppC S Protein of unknown function (DUF2515)
CMLFLONI_02266 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
CMLFLONI_02267 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
CMLFLONI_02268 4.7e-93 ypoC
CMLFLONI_02269 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CMLFLONI_02270 5.7e-129 dnaD L DNA replication protein DnaD
CMLFLONI_02271 3.1e-138 asnS 6.1.1.22 J asparaginyl-tRNA
CMLFLONI_02272 7.6e-97 asnS 6.1.1.22 J asparaginyl-tRNA
CMLFLONI_02273 1.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
CMLFLONI_02274 2.2e-79 ypmB S protein conserved in bacteria
CMLFLONI_02275 6.7e-23 ypmA S Protein of unknown function (DUF4264)
CMLFLONI_02276 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
CMLFLONI_02277 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
CMLFLONI_02278 4.7e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
CMLFLONI_02279 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
CMLFLONI_02280 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
CMLFLONI_02281 6.6e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CMLFLONI_02282 5.3e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
CMLFLONI_02283 1.7e-128 bshB1 S proteins, LmbE homologs
CMLFLONI_02284 7.9e-70 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
CMLFLONI_02285 4.5e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
CMLFLONI_02286 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
CMLFLONI_02287 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
CMLFLONI_02288 6.1e-143 ypjB S sporulation protein
CMLFLONI_02289 4.4e-98 ypjA S membrane
CMLFLONI_02290 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
CMLFLONI_02291 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
CMLFLONI_02292 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
CMLFLONI_02293 4.2e-77 ypiF S Protein of unknown function (DUF2487)
CMLFLONI_02294 1.1e-98 ypiB S Belongs to the UPF0302 family
CMLFLONI_02295 4.1e-234 S COG0457 FOG TPR repeat
CMLFLONI_02296 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
CMLFLONI_02297 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
CMLFLONI_02298 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
CMLFLONI_02299 8e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
CMLFLONI_02300 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
CMLFLONI_02301 3.3e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
CMLFLONI_02302 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
CMLFLONI_02303 1.4e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CMLFLONI_02304 7.6e-291 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CMLFLONI_02305 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
CMLFLONI_02306 5.8e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
CMLFLONI_02307 9.4e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
CMLFLONI_02308 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
CMLFLONI_02309 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
CMLFLONI_02310 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMLFLONI_02311 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
CMLFLONI_02312 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
CMLFLONI_02313 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
CMLFLONI_02314 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
CMLFLONI_02315 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
CMLFLONI_02316 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
CMLFLONI_02317 1.5e-135 yphF
CMLFLONI_02318 1.6e-18 yphE S Protein of unknown function (DUF2768)
CMLFLONI_02319 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
CMLFLONI_02320 1.5e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
CMLFLONI_02321 2.3e-27 ypzH
CMLFLONI_02322 2.5e-161 seaA S YIEGIA protein
CMLFLONI_02323 1.3e-102 yphA
CMLFLONI_02324 1e-07 S YpzI-like protein
CMLFLONI_02325 1.2e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
CMLFLONI_02326 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
CMLFLONI_02327 1.2e-110 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
CMLFLONI_02328 5e-21 S Family of unknown function (DUF5359)
CMLFLONI_02329 6.6e-111 ypfA M Flagellar protein YcgR
CMLFLONI_02330 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
CMLFLONI_02331 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
CMLFLONI_02332 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
CMLFLONI_02333 2.8e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
CMLFLONI_02334 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CMLFLONI_02335 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
CMLFLONI_02336 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
CMLFLONI_02337 2.8e-81 ypbF S Protein of unknown function (DUF2663)
CMLFLONI_02338 1.7e-78 ypbE M Lysin motif
CMLFLONI_02339 1.1e-99 ypbD S metal-dependent membrane protease
CMLFLONI_02340 2.7e-285 recQ 3.6.4.12 L DNA helicase
CMLFLONI_02341 1.8e-198 ypbB 5.1.3.1 S protein conserved in bacteria
CMLFLONI_02342 4.7e-41 fer C Ferredoxin
CMLFLONI_02343 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
CMLFLONI_02344 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMLFLONI_02345 9.4e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
CMLFLONI_02346 1.5e-184 rsiX
CMLFLONI_02347 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_02348 0.0 resE 2.7.13.3 T Histidine kinase
CMLFLONI_02349 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_02350 1.3e-213 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
CMLFLONI_02351 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
CMLFLONI_02352 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
CMLFLONI_02353 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMLFLONI_02354 1.9e-87 spmB S Spore maturation protein
CMLFLONI_02355 3.5e-103 spmA S Spore maturation protein
CMLFLONI_02356 8.9e-212 dacB 3.4.16.4 M Belongs to the peptidase S11 family
CMLFLONI_02357 7.6e-97 ypuI S Protein of unknown function (DUF3907)
CMLFLONI_02358 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CMLFLONI_02359 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CMLFLONI_02360 3.6e-91 ypuF S Domain of unknown function (DUF309)
CMLFLONI_02361 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_02362 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
CMLFLONI_02363 3.5e-227 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CMLFLONI_02364 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
CMLFLONI_02365 8.4e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CMLFLONI_02366 7.8e-55 ypuD
CMLFLONI_02367 4e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
CMLFLONI_02368 1.1e-12 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
CMLFLONI_02370 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CMLFLONI_02371 2.4e-148 ypuA S Secreted protein
CMLFLONI_02372 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
CMLFLONI_02373 1.4e-273 spoVAF EG Stage V sporulation protein AF
CMLFLONI_02374 1.4e-110 spoVAEA S stage V sporulation protein
CMLFLONI_02375 2.2e-57 spoVAEB S stage V sporulation protein
CMLFLONI_02376 9e-192 spoVAD I Stage V sporulation protein AD
CMLFLONI_02377 2.3e-78 spoVAC S stage V sporulation protein AC
CMLFLONI_02378 1e-67 spoVAB S Stage V sporulation protein AB
CMLFLONI_02379 9.6e-112 spoVAA S Stage V sporulation protein AA
CMLFLONI_02380 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_02381 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
CMLFLONI_02382 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
CMLFLONI_02383 1.1e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
CMLFLONI_02384 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
CMLFLONI_02385 8.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
CMLFLONI_02386 5.7e-166 xerD L recombinase XerD
CMLFLONI_02387 3.7e-37 S Protein of unknown function (DUF4227)
CMLFLONI_02388 2.4e-80 fur P Belongs to the Fur family
CMLFLONI_02389 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
CMLFLONI_02390 5.5e-30 yqkK
CMLFLONI_02391 5.5e-242 mleA 1.1.1.38 C malic enzyme
CMLFLONI_02392 9.1e-235 mleN C Na H antiporter
CMLFLONI_02393 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
CMLFLONI_02394 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
CMLFLONI_02395 4.5e-58 ansR K Transcriptional regulator
CMLFLONI_02396 5.3e-220 yqxK 3.6.4.12 L DNA helicase
CMLFLONI_02397 5.8e-19 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CMLFLONI_02398 3.8e-31 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
CMLFLONI_02400 9.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
CMLFLONI_02401 3.1e-12 yqkE S Protein of unknown function (DUF3886)
CMLFLONI_02402 3.9e-170 yqkD S COG1073 Hydrolases of the alpha beta superfamily
CMLFLONI_02403 4.6e-38 yqkC S Protein of unknown function (DUF2552)
CMLFLONI_02404 2.8e-54 yqkB S Belongs to the HesB IscA family
CMLFLONI_02405 9.8e-194 yqkA K GrpB protein
CMLFLONI_02406 2.6e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
CMLFLONI_02407 1.8e-86 yqjY K acetyltransferase
CMLFLONI_02408 1.7e-49 S YolD-like protein
CMLFLONI_02409 2.9e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMLFLONI_02411 2e-225 yqjV G Major Facilitator Superfamily
CMLFLONI_02413 1e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_02414 2.7e-177 coaA 2.7.1.33 F Pantothenic acid kinase
CMLFLONI_02415 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
CMLFLONI_02416 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_02417 1.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
CMLFLONI_02418 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMLFLONI_02419 0.0 rocB E arginine degradation protein
CMLFLONI_02420 2.6e-191 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
CMLFLONI_02421 3.6e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
CMLFLONI_02422 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMLFLONI_02423 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
CMLFLONI_02424 1.3e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
CMLFLONI_02425 3.4e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMLFLONI_02426 1.2e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CMLFLONI_02427 6.2e-24 yqzJ
CMLFLONI_02428 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMLFLONI_02429 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
CMLFLONI_02430 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
CMLFLONI_02431 1.5e-286 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
CMLFLONI_02432 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
CMLFLONI_02434 1.4e-98 yqjB S protein conserved in bacteria
CMLFLONI_02435 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
CMLFLONI_02436 2.2e-128 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CMLFLONI_02437 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
CMLFLONI_02438 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
CMLFLONI_02439 9.3e-77 yqiW S Belongs to the UPF0403 family
CMLFLONI_02440 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
CMLFLONI_02441 7.9e-208 norA EGP Major facilitator Superfamily
CMLFLONI_02442 1.2e-32 bmrR K helix_turn_helix, mercury resistance
CMLFLONI_02443 1.8e-107 bmrR K helix_turn_helix, mercury resistance
CMLFLONI_02444 1.1e-218 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
CMLFLONI_02445 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
CMLFLONI_02446 1.8e-184 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
CMLFLONI_02447 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
CMLFLONI_02448 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
CMLFLONI_02449 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
CMLFLONI_02450 2.1e-155 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
CMLFLONI_02451 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
CMLFLONI_02452 4e-34 yqzF S Protein of unknown function (DUF2627)
CMLFLONI_02453 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
CMLFLONI_02454 4.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
CMLFLONI_02455 5.4e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
CMLFLONI_02456 2e-211 mmgC I acyl-CoA dehydrogenase
CMLFLONI_02457 8.3e-154 hbdA 1.1.1.157 I Dehydrogenase
CMLFLONI_02458 1.9e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
CMLFLONI_02459 2.4e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
CMLFLONI_02460 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
CMLFLONI_02461 5.9e-27
CMLFLONI_02462 3.6e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
CMLFLONI_02464 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
CMLFLONI_02465 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
CMLFLONI_02466 0.0 recN L May be involved in recombinational repair of damaged DNA
CMLFLONI_02467 1.7e-78 argR K Regulates arginine biosynthesis genes
CMLFLONI_02468 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
CMLFLONI_02469 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CMLFLONI_02470 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
CMLFLONI_02471 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMLFLONI_02472 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
CMLFLONI_02473 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
CMLFLONI_02474 6.2e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
CMLFLONI_02475 2.1e-67 yqhY S protein conserved in bacteria
CMLFLONI_02476 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
CMLFLONI_02477 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
CMLFLONI_02478 9.9e-91 spoIIIAH S SpoIIIAH-like protein
CMLFLONI_02479 2.2e-109 spoIIIAG S stage III sporulation protein AG
CMLFLONI_02480 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
CMLFLONI_02481 1.3e-197 spoIIIAE S stage III sporulation protein AE
CMLFLONI_02482 2.3e-58 spoIIIAD S Stage III sporulation protein AD
CMLFLONI_02483 7.6e-29 spoIIIAC S stage III sporulation protein AC
CMLFLONI_02484 4.1e-84 spoIIIAB S Stage III sporulation protein
CMLFLONI_02485 4e-170 spoIIIAA S stage III sporulation protein AA
CMLFLONI_02486 7.9e-37 yqhV S Protein of unknown function (DUF2619)
CMLFLONI_02487 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
CMLFLONI_02488 4.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
CMLFLONI_02489 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
CMLFLONI_02490 2.3e-93 yqhR S Conserved membrane protein YqhR
CMLFLONI_02491 3e-173 yqhQ S Protein of unknown function (DUF1385)
CMLFLONI_02492 2.2e-61 yqhP
CMLFLONI_02493 3.4e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
CMLFLONI_02494 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
CMLFLONI_02495 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
CMLFLONI_02496 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
CMLFLONI_02497 1.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CMLFLONI_02498 1.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CMLFLONI_02499 9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
CMLFLONI_02500 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CMLFLONI_02501 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
CMLFLONI_02502 1.2e-24 sinI S Anti-repressor SinI
CMLFLONI_02503 1e-54 sinR K transcriptional
CMLFLONI_02504 1.2e-140 tasA S Cell division protein FtsN
CMLFLONI_02505 6.7e-59 sipW 3.4.21.89 U Signal peptidase
CMLFLONI_02506 9.7e-114 yqxM
CMLFLONI_02507 7.3e-54 yqzG S Protein of unknown function (DUF3889)
CMLFLONI_02508 1.4e-26 yqzE S YqzE-like protein
CMLFLONI_02509 4e-44 S ComG operon protein 7
CMLFLONI_02510 4.6e-45 comGF U Putative Competence protein ComGF
CMLFLONI_02511 1.1e-59 comGE
CMLFLONI_02512 4.4e-71 gspH NU protein transport across the cell outer membrane
CMLFLONI_02513 1.4e-47 comGC U Required for transformation and DNA binding
CMLFLONI_02514 1.1e-173 comGB NU COG1459 Type II secretory pathway, component PulF
CMLFLONI_02515 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CMLFLONI_02516 4e-173 corA P Mg2 transporter protein
CMLFLONI_02517 3.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CMLFLONI_02518 5.4e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
CMLFLONI_02520 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
CMLFLONI_02521 1.8e-37 yqgY S Protein of unknown function (DUF2626)
CMLFLONI_02522 7.3e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
CMLFLONI_02523 8.9e-23 yqgW S Protein of unknown function (DUF2759)
CMLFLONI_02524 6.9e-50 yqgV S Thiamine-binding protein
CMLFLONI_02525 3.9e-198 yqgU
CMLFLONI_02526 2.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
CMLFLONI_02527 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CMLFLONI_02528 5.2e-181 glcK 2.7.1.2 G Glucokinase
CMLFLONI_02529 3.1e-33 yqgQ S Protein conserved in bacteria
CMLFLONI_02530 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
CMLFLONI_02531 2.5e-09 yqgO
CMLFLONI_02532 2e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CMLFLONI_02533 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
CMLFLONI_02534 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
CMLFLONI_02536 3.5e-50 yqzD
CMLFLONI_02537 7.3e-72 yqzC S YceG-like family
CMLFLONI_02538 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMLFLONI_02539 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
CMLFLONI_02540 8.2e-157 pstA P Phosphate transport system permease
CMLFLONI_02541 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
CMLFLONI_02542 2e-150 pstS P Phosphate
CMLFLONI_02543 0.0 pbpA 3.4.16.4 M penicillin-binding protein
CMLFLONI_02544 2.5e-231 yqgE EGP Major facilitator superfamily
CMLFLONI_02545 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
CMLFLONI_02546 4e-73 yqgC S protein conserved in bacteria
CMLFLONI_02547 1.5e-130 yqgB S Protein of unknown function (DUF1189)
CMLFLONI_02548 1.2e-46 yqfZ M LysM domain
CMLFLONI_02549 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
CMLFLONI_02550 4.3e-62 yqfX S membrane
CMLFLONI_02551 7.9e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
CMLFLONI_02552 1.9e-77 zur P Belongs to the Fur family
CMLFLONI_02553 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
CMLFLONI_02554 2.1e-36 yqfT S Protein of unknown function (DUF2624)
CMLFLONI_02555 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
CMLFLONI_02556 2.9e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
CMLFLONI_02557 2.9e-14 yqfQ S YqfQ-like protein
CMLFLONI_02558 2.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
CMLFLONI_02559 4.8e-210 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CMLFLONI_02560 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
CMLFLONI_02561 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
CMLFLONI_02562 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
CMLFLONI_02563 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
CMLFLONI_02564 4.5e-88 yaiI S Belongs to the UPF0178 family
CMLFLONI_02565 1.7e-148 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
CMLFLONI_02566 4.5e-112 ccpN K CBS domain
CMLFLONI_02567 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
CMLFLONI_02568 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
CMLFLONI_02569 1.8e-144 recO L Involved in DNA repair and RecF pathway recombination
CMLFLONI_02570 8.4e-19 S YqzL-like protein
CMLFLONI_02571 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CMLFLONI_02572 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
CMLFLONI_02573 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
CMLFLONI_02574 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
CMLFLONI_02575 0.0 yqfF S membrane-associated HD superfamily hydrolase
CMLFLONI_02577 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
CMLFLONI_02578 1.4e-183 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
CMLFLONI_02579 2.7e-45 yqfC S sporulation protein YqfC
CMLFLONI_02580 3.7e-22 yqfB
CMLFLONI_02581 4.3e-122 yqfA S UPF0365 protein
CMLFLONI_02582 1.7e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
CMLFLONI_02583 2.5e-61 yqeY S Yqey-like protein
CMLFLONI_02584 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
CMLFLONI_02585 4.1e-157 yqeW P COG1283 Na phosphate symporter
CMLFLONI_02586 7.9e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
CMLFLONI_02587 2.1e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
CMLFLONI_02588 4.6e-174 prmA J Methylates ribosomal protein L11
CMLFLONI_02589 3.6e-181 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
CMLFLONI_02590 0.0 dnaK O Heat shock 70 kDa protein
CMLFLONI_02591 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CMLFLONI_02592 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
CMLFLONI_02593 2.9e-215 hemN H Involved in the biosynthesis of porphyrin-containing compound
CMLFLONI_02594 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
CMLFLONI_02595 3.6e-52 yqxA S Protein of unknown function (DUF3679)
CMLFLONI_02596 1.5e-222 spoIIP M stage II sporulation protein P
CMLFLONI_02597 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
CMLFLONI_02598 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
CMLFLONI_02599 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
CMLFLONI_02600 4.1e-15 S YqzM-like protein
CMLFLONI_02601 0.0 comEC S Competence protein ComEC
CMLFLONI_02602 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
CMLFLONI_02603 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
CMLFLONI_02604 2.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CMLFLONI_02605 3.2e-138 yqeM Q Methyltransferase
CMLFLONI_02606 1.3e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
CMLFLONI_02607 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
CMLFLONI_02608 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CMLFLONI_02609 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
CMLFLONI_02610 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CMLFLONI_02611 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
CMLFLONI_02612 5.3e-95 yqeG S hydrolase of the HAD superfamily
CMLFLONI_02614 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
CMLFLONI_02615 8.9e-136 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CMLFLONI_02616 3.3e-104 yqeD S SNARE associated Golgi protein
CMLFLONI_02617 6.1e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
CMLFLONI_02618 5.7e-132 yqeB
CMLFLONI_02619 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
CMLFLONI_02620 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_02621 1.4e-281 cisA2 L Recombinase
CMLFLONI_02622 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
CMLFLONI_02623 3.3e-181 arsB 1.20.4.1 P Arsenic resistance protein
CMLFLONI_02624 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_02625 2.1e-54 arsR K ArsR family transcriptional regulator
CMLFLONI_02626 4.8e-145 yqcI S YqcI/YcgG family
CMLFLONI_02627 1.6e-96 S Tetratricopeptide repeat
CMLFLONI_02630 3.8e-277 A Pre-toxin TG
CMLFLONI_02631 1.1e-104 S Suppressor of fused protein (SUFU)
CMLFLONI_02633 5e-60
CMLFLONI_02635 4.5e-141 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
CMLFLONI_02636 1.9e-66 S Bacteriophage holin family
CMLFLONI_02637 1.4e-159 xepA
CMLFLONI_02638 1.3e-23
CMLFLONI_02639 4.1e-56 xkdW S XkdW protein
CMLFLONI_02640 5.9e-221
CMLFLONI_02641 9e-38
CMLFLONI_02642 8.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
CMLFLONI_02643 2.2e-185 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
CMLFLONI_02644 5e-67 xkdS S Protein of unknown function (DUF2634)
CMLFLONI_02645 1.8e-38 xkdR S Protein of unknown function (DUF2577)
CMLFLONI_02646 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
CMLFLONI_02647 9e-114 xkdP S Lysin motif
CMLFLONI_02648 0.0 xkdO L Transglycosylase SLT domain
CMLFLONI_02649 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
CMLFLONI_02651 3.6e-76 xkdM S Phage tail tube protein
CMLFLONI_02652 5.5e-256 xkdK S Phage tail sheath C-terminal domain
CMLFLONI_02653 3.2e-26
CMLFLONI_02654 1.4e-77
CMLFLONI_02655 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
CMLFLONI_02656 6.7e-65 yqbH S Domain of unknown function (DUF3599)
CMLFLONI_02657 2.1e-67 S Protein of unknown function (DUF3199)
CMLFLONI_02658 3.6e-51 S YqbF, hypothetical protein domain
CMLFLONI_02659 1.9e-167 xkdG S Phage capsid family
CMLFLONI_02660 9.4e-122 yqbD 2.1.1.72 L Putative phage serine protease XkdF
CMLFLONI_02662 1.4e-151 S Phage Mu protein F like protein
CMLFLONI_02663 6.3e-290 yqbA S portal protein
CMLFLONI_02664 2.1e-246 S phage terminase, large subunit
CMLFLONI_02665 1.5e-95 yqaS L DNA packaging
CMLFLONI_02667 3.7e-76 L Transposase
CMLFLONI_02668 1.5e-06
CMLFLONI_02669 2.4e-30 yqaO S Phage-like element PBSX protein XtrA
CMLFLONI_02670 5.7e-71 rusA L Endodeoxyribonuclease RusA
CMLFLONI_02672 2.2e-162 xkdC L IstB-like ATP binding protein
CMLFLONI_02673 9.8e-121 3.1.3.16 L DnaD domain protein
CMLFLONI_02674 1.2e-149 recT L RecT family
CMLFLONI_02675 4.9e-163 yqaJ L YqaJ-like viral recombinase domain
CMLFLONI_02679 4.4e-103
CMLFLONI_02681 6.5e-37 K Helix-turn-helix XRE-family like proteins
CMLFLONI_02682 1.1e-56 K sequence-specific DNA binding
CMLFLONI_02684 1e-101 adk 2.7.4.3 F adenylate kinase activity
CMLFLONI_02685 4.4e-94 yqaB E IrrE N-terminal-like domain
CMLFLONI_02686 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CMLFLONI_02687 3.4e-68 psiE S Protein PsiE homolog
CMLFLONI_02688 3.8e-235 yrkQ T Histidine kinase
CMLFLONI_02689 2.6e-126 T Transcriptional regulator
CMLFLONI_02690 8.2e-224 yrkO P Protein of unknown function (DUF418)
CMLFLONI_02691 6e-105 yrkN K Acetyltransferase (GNAT) family
CMLFLONI_02692 1.5e-97 ywrO S Flavodoxin-like fold
CMLFLONI_02693 2.8e-79 S Protein of unknown function with HXXEE motif
CMLFLONI_02694 7.4e-117 yrkJ S membrane transporter protein
CMLFLONI_02695 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
CMLFLONI_02696 2.3e-212 yrkH P Rhodanese Homology Domain
CMLFLONI_02697 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
CMLFLONI_02698 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
CMLFLONI_02699 7.8e-39 yrkD S protein conserved in bacteria
CMLFLONI_02700 1.2e-105 yrkC G Cupin domain
CMLFLONI_02701 3.1e-150 bltR K helix_turn_helix, mercury resistance
CMLFLONI_02702 3.3e-209 blt EGP Major facilitator Superfamily
CMLFLONI_02703 5.9e-82 bltD 2.3.1.57 K FR47-like protein
CMLFLONI_02704 3e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
CMLFLONI_02705 8.7e-16 S YrzO-like protein
CMLFLONI_02706 2.7e-169 yrdR EG EamA-like transporter family
CMLFLONI_02707 5.9e-160 yrdQ K Transcriptional regulator
CMLFLONI_02708 2e-199 trkA P Oxidoreductase
CMLFLONI_02709 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
CMLFLONI_02710 1.3e-66 yodA S tautomerase
CMLFLONI_02711 2.5e-161 gltR K LysR substrate binding domain
CMLFLONI_02713 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
CMLFLONI_02714 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
CMLFLONI_02715 2.8e-137 azlC E AzlC protein
CMLFLONI_02716 2.2e-79 bkdR K helix_turn_helix ASNC type
CMLFLONI_02717 4.1e-46 yrdF K ribonuclease inhibitor
CMLFLONI_02718 4.1e-231 cypA C Cytochrome P450
CMLFLONI_02719 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
CMLFLONI_02720 1.9e-57 S Protein of unknown function (DUF2568)
CMLFLONI_02721 1.2e-91 yrdA S DinB family
CMLFLONI_02722 4.2e-166 aadK G Streptomycin adenylyltransferase
CMLFLONI_02723 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
CMLFLONI_02724 1.5e-53 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMLFLONI_02725 1.3e-78 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMLFLONI_02726 8.7e-125 yrpD S Domain of unknown function, YrpD
CMLFLONI_02727 1.5e-100 K helix_turn_helix gluconate operon transcriptional repressor
CMLFLONI_02729 7.4e-210 rbtT P Major Facilitator Superfamily
CMLFLONI_02730 5.6e-114 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_02731 3.5e-153 2.2.1.1 G Transketolase, pyrimidine binding domain
CMLFLONI_02732 6.4e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
CMLFLONI_02733 5.6e-98 flr S Flavin reductase like domain
CMLFLONI_02734 7.2e-118 bmrR K helix_turn_helix, mercury resistance
CMLFLONI_02735 1.3e-47 yjbR S YjbR
CMLFLONI_02736 1.1e-25 epsA I Passenger-associated-transport-repeat
CMLFLONI_02737 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
CMLFLONI_02738 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_02739 4.5e-188 yrpG C Aldo/keto reductase family
CMLFLONI_02740 2.8e-225 yraO C Citrate transporter
CMLFLONI_02741 1.2e-163 yraN K Transcriptional regulator
CMLFLONI_02742 2.4e-206 yraM S PrpF protein
CMLFLONI_02744 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
CMLFLONI_02745 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_02746 3.2e-155 S Alpha beta hydrolase
CMLFLONI_02747 4.9e-60 T sh3 domain protein
CMLFLONI_02748 2.4e-61 T sh3 domain protein
CMLFLONI_02749 1.3e-66 E Glyoxalase-like domain
CMLFLONI_02750 5.3e-37 yraG
CMLFLONI_02751 6.4e-63 yraF M Spore coat protein
CMLFLONI_02752 1.1e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CMLFLONI_02753 1.7e-25 yraE
CMLFLONI_02754 1.1e-49 yraD M Spore coat protein
CMLFLONI_02755 4.3e-47 yraB K helix_turn_helix, mercury resistance
CMLFLONI_02756 7.4e-26 yphJ 4.1.1.44 S peroxiredoxin activity
CMLFLONI_02757 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
CMLFLONI_02758 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
CMLFLONI_02759 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CMLFLONI_02760 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
CMLFLONI_02761 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
CMLFLONI_02762 1.2e-80 levE 2.7.1.202 G PTS system mannose fructose sorbose family
CMLFLONI_02763 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
CMLFLONI_02764 0.0 levR K PTS system fructose IIA component
CMLFLONI_02765 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_02766 3.6e-106 yrhP E LysE type translocator
CMLFLONI_02767 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
CMLFLONI_02768 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_02769 3.8e-151 rsiV S Protein of unknown function (DUF3298)
CMLFLONI_02770 3.1e-246 yrhL I Acyltransferase family
CMLFLONI_02771 6e-58 yrhL I Acyltransferase family
CMLFLONI_02772 1.4e-44 yrhK S YrhK-like protein
CMLFLONI_02773 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
CMLFLONI_02774 1.8e-104 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
CMLFLONI_02775 7.2e-95 yrhH Q methyltransferase
CMLFLONI_02778 1.8e-142 focA P Formate nitrite
CMLFLONI_02779 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
CMLFLONI_02780 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
CMLFLONI_02781 1.4e-78 yrhD S Protein of unknown function (DUF1641)
CMLFLONI_02782 4.6e-35 yrhC S YrhC-like protein
CMLFLONI_02783 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
CMLFLONI_02784 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
CMLFLONI_02785 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CMLFLONI_02786 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
CMLFLONI_02787 3.5e-26 yrzA S Protein of unknown function (DUF2536)
CMLFLONI_02788 4.2e-63 yrrS S Protein of unknown function (DUF1510)
CMLFLONI_02789 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
CMLFLONI_02790 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
CMLFLONI_02791 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
CMLFLONI_02792 2.7e-246 yegQ O COG0826 Collagenase and related proteases
CMLFLONI_02793 7.8e-174 yegQ O Peptidase U32
CMLFLONI_02794 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
CMLFLONI_02795 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CMLFLONI_02796 1.2e-45 yrzB S Belongs to the UPF0473 family
CMLFLONI_02797 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CMLFLONI_02798 1.7e-41 yrzL S Belongs to the UPF0297 family
CMLFLONI_02799 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
CMLFLONI_02800 2.7e-170 yrrI S AI-2E family transporter
CMLFLONI_02801 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CMLFLONI_02802 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
CMLFLONI_02803 6.8e-108 gluC P ABC transporter
CMLFLONI_02804 7.6e-107 glnP P ABC transporter
CMLFLONI_02805 8e-08 S Protein of unknown function (DUF3918)
CMLFLONI_02806 9.8e-31 yrzR
CMLFLONI_02807 1.8e-83 yrrD S protein conserved in bacteria
CMLFLONI_02808 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
CMLFLONI_02809 1.4e-15 S COG0457 FOG TPR repeat
CMLFLONI_02810 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
CMLFLONI_02811 2.2e-210 iscS 2.8.1.7 E Cysteine desulfurase
CMLFLONI_02812 1.2e-70 cymR K Transcriptional regulator
CMLFLONI_02813 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
CMLFLONI_02814 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
CMLFLONI_02815 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CMLFLONI_02816 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
CMLFLONI_02818 1.1e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
CMLFLONI_02819 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
CMLFLONI_02820 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CMLFLONI_02821 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
CMLFLONI_02822 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
CMLFLONI_02823 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
CMLFLONI_02824 4.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
CMLFLONI_02825 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CMLFLONI_02826 1.6e-48 yrzD S Post-transcriptional regulator
CMLFLONI_02827 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_02828 1.7e-111 yrbG S membrane
CMLFLONI_02829 2.2e-73 yrzE S Protein of unknown function (DUF3792)
CMLFLONI_02830 1.1e-38 yajC U Preprotein translocase subunit YajC
CMLFLONI_02831 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
CMLFLONI_02832 7.5e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
CMLFLONI_02833 2.6e-18 yrzS S Protein of unknown function (DUF2905)
CMLFLONI_02834 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
CMLFLONI_02835 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
CMLFLONI_02836 4.8e-93 bofC S BofC C-terminal domain
CMLFLONI_02837 5.3e-253 csbX EGP Major facilitator Superfamily
CMLFLONI_02838 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
CMLFLONI_02839 6.5e-119 yrzF T serine threonine protein kinase
CMLFLONI_02841 2.6e-35 S Family of unknown function (DUF5412)
CMLFLONI_02842 5.3e-262 alsT E Sodium alanine symporter
CMLFLONI_02843 3.6e-126 yebC K transcriptional regulatory protein
CMLFLONI_02844 1.3e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CMLFLONI_02845 8.6e-154 safA M spore coat assembly protein SafA
CMLFLONI_02846 4.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CMLFLONI_02847 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
CMLFLONI_02848 7e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
CMLFLONI_02849 5.9e-227 nifS 2.8.1.7 E Cysteine desulfurase
CMLFLONI_02850 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
CMLFLONI_02851 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
CMLFLONI_02852 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
CMLFLONI_02853 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CMLFLONI_02854 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
CMLFLONI_02855 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
CMLFLONI_02856 4.1e-56 ysxB J ribosomal protein
CMLFLONI_02857 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
CMLFLONI_02858 9.2e-161 spoIVFB S Stage IV sporulation protein
CMLFLONI_02859 8.5e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
CMLFLONI_02860 2.5e-144 minD D Belongs to the ParA family
CMLFLONI_02861 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
CMLFLONI_02862 1.4e-84 mreD M shape-determining protein
CMLFLONI_02863 2.8e-157 mreC M Involved in formation and maintenance of cell shape
CMLFLONI_02864 1.8e-184 mreB D Rod shape-determining protein MreB
CMLFLONI_02865 1.5e-124 radC E Belongs to the UPF0758 family
CMLFLONI_02866 2.8e-102 maf D septum formation protein Maf
CMLFLONI_02867 3.8e-166 spoIIB S Sporulation related domain
CMLFLONI_02868 3.3e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
CMLFLONI_02869 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
CMLFLONI_02870 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
CMLFLONI_02871 1.6e-25
CMLFLONI_02872 1.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CMLFLONI_02873 1.6e-220 spoVID M stage VI sporulation protein D
CMLFLONI_02874 1.6e-246 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
CMLFLONI_02875 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
CMLFLONI_02876 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
CMLFLONI_02877 8.7e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
CMLFLONI_02878 3.6e-146 hemX O cytochrome C
CMLFLONI_02879 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
CMLFLONI_02880 3.2e-89 ysxD
CMLFLONI_02881 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
CMLFLONI_02882 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
CMLFLONI_02883 1.6e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
CMLFLONI_02884 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
CMLFLONI_02885 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
CMLFLONI_02886 1.1e-186 ysoA H Tetratricopeptide repeat
CMLFLONI_02887 7.6e-114 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMLFLONI_02888 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
CMLFLONI_02889 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
CMLFLONI_02890 1.3e-287 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CMLFLONI_02891 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
CMLFLONI_02892 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
CMLFLONI_02893 0.0 ilvB 2.2.1.6 E Acetolactate synthase
CMLFLONI_02895 7.4e-77 ysnE K acetyltransferase
CMLFLONI_02896 2.9e-132 ysnF S protein conserved in bacteria
CMLFLONI_02898 5.3e-92 ysnB S Phosphoesterase
CMLFLONI_02899 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
CMLFLONI_02900 9e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
CMLFLONI_02901 2.9e-196 gerM S COG5401 Spore germination protein
CMLFLONI_02902 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
CMLFLONI_02903 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_02904 3.3e-30 gerE K Transcriptional regulator
CMLFLONI_02905 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
CMLFLONI_02906 1.7e-147 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CMLFLONI_02907 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
CMLFLONI_02908 2.4e-107 sdhC C succinate dehydrogenase
CMLFLONI_02909 1.2e-79 yslB S Protein of unknown function (DUF2507)
CMLFLONI_02910 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
CMLFLONI_02911 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
CMLFLONI_02912 2e-52 trxA O Belongs to the thioredoxin family
CMLFLONI_02913 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
CMLFLONI_02915 1.3e-176 etfA C Electron transfer flavoprotein
CMLFLONI_02916 1.3e-134 etfB C Electron transfer flavoprotein
CMLFLONI_02917 2.7e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
CMLFLONI_02918 4e-99 fadR K Transcriptional regulator
CMLFLONI_02919 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
CMLFLONI_02920 7.3e-68 yshE S membrane
CMLFLONI_02921 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
CMLFLONI_02922 0.0 polX L COG1796 DNA polymerase IV (family X)
CMLFLONI_02923 1.3e-85 cvpA S membrane protein, required for colicin V production
CMLFLONI_02924 6.6e-30 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
CMLFLONI_02925 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CMLFLONI_02926 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMLFLONI_02927 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
CMLFLONI_02928 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CMLFLONI_02929 5.8e-32 sspI S Belongs to the SspI family
CMLFLONI_02930 8.6e-204 ysfB KT regulator
CMLFLONI_02931 5.7e-261 glcD 1.1.3.15 C Glycolate oxidase subunit
CMLFLONI_02932 2.3e-256 glcF C Glycolate oxidase
CMLFLONI_02933 4.5e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
CMLFLONI_02934 0.0 cstA T Carbon starvation protein
CMLFLONI_02935 3.9e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
CMLFLONI_02936 3.4e-144 araQ G transport system permease
CMLFLONI_02937 4.2e-167 araP G carbohydrate transport
CMLFLONI_02938 3.4e-252 araN G carbohydrate transport
CMLFLONI_02939 7.5e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
CMLFLONI_02940 1.1e-144 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
CMLFLONI_02941 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
CMLFLONI_02942 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
CMLFLONI_02943 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
CMLFLONI_02944 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CMLFLONI_02945 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
CMLFLONI_02946 3.5e-67 ysdB S Sigma-w pathway protein YsdB
CMLFLONI_02947 7.5e-45 ysdA S Membrane
CMLFLONI_02948 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
CMLFLONI_02949 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
CMLFLONI_02950 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CMLFLONI_02952 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CMLFLONI_02953 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
CMLFLONI_02954 1.6e-129 lytT T COG3279 Response regulator of the LytR AlgR family
CMLFLONI_02955 0.0 lytS 2.7.13.3 T Histidine kinase
CMLFLONI_02956 2.8e-148 ysaA S HAD-hyrolase-like
CMLFLONI_02957 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMLFLONI_02958 1.4e-158 ytxC S YtxC-like family
CMLFLONI_02959 6e-109 ytxB S SNARE associated Golgi protein
CMLFLONI_02960 6.6e-173 dnaI L Primosomal protein DnaI
CMLFLONI_02961 7.7e-266 dnaB L Membrane attachment protein
CMLFLONI_02962 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CMLFLONI_02963 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
CMLFLONI_02964 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMLFLONI_02965 4.9e-66 ytcD K Transcriptional regulator
CMLFLONI_02966 2.4e-204 ytbD EGP Major facilitator Superfamily
CMLFLONI_02967 2e-160 ytbE S reductase
CMLFLONI_02968 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CMLFLONI_02969 1.1e-107 ytaF P Probably functions as a manganese efflux pump
CMLFLONI_02970 3.9e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
CMLFLONI_02971 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
CMLFLONI_02972 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
CMLFLONI_02973 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_02974 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
CMLFLONI_02975 4.1e-242 icd 1.1.1.42 C isocitrate
CMLFLONI_02976 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
CMLFLONI_02977 2.3e-70 yeaL S membrane
CMLFLONI_02978 2.6e-192 ytvI S sporulation integral membrane protein YtvI
CMLFLONI_02979 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
CMLFLONI_02980 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
CMLFLONI_02981 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
CMLFLONI_02982 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
CMLFLONI_02983 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
CMLFLONI_02984 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
CMLFLONI_02985 0.0 dnaE 2.7.7.7 L DNA polymerase
CMLFLONI_02986 3.2e-56 ytrH S Sporulation protein YtrH
CMLFLONI_02987 8.2e-69 ytrI
CMLFLONI_02988 9.2e-29
CMLFLONI_02989 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
CMLFLONI_02990 7.6e-46 ytpI S YtpI-like protein
CMLFLONI_02991 8e-241 ytoI K transcriptional regulator containing CBS domains
CMLFLONI_02992 1.4e-156 ytnM S membrane transporter protein
CMLFLONI_02993 1.6e-238 ytnL 3.5.1.47 E hydrolase activity
CMLFLONI_02994 3.4e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
CMLFLONI_02995 3.2e-253 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_02996 2.4e-46 ytnI O COG0695 Glutaredoxin and related proteins
CMLFLONI_02997 7.6e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_02998 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
CMLFLONI_02999 1.6e-118 tcyM U Binding-protein-dependent transport system inner membrane component
CMLFLONI_03000 8.2e-123 tcyL P Binding-protein-dependent transport system inner membrane component
CMLFLONI_03001 3.7e-148 tcyK M Bacterial periplasmic substrate-binding proteins
CMLFLONI_03002 3.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
CMLFLONI_03003 3.1e-98 ytmI K Acetyltransferase (GNAT) domain
CMLFLONI_03004 2.9e-173 ytlI K LysR substrate binding domain
CMLFLONI_03005 1.7e-130 ytkL S Belongs to the UPF0173 family
CMLFLONI_03006 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_03008 1.2e-266 argH 4.3.2.1 E argininosuccinate lyase
CMLFLONI_03009 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
CMLFLONI_03010 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
CMLFLONI_03011 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CMLFLONI_03012 7e-165 ytxK 2.1.1.72 L DNA methylase
CMLFLONI_03013 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
CMLFLONI_03014 8.7e-70 ytfJ S Sporulation protein YtfJ
CMLFLONI_03015 1.6e-115 ytfI S Protein of unknown function (DUF2953)
CMLFLONI_03016 8.5e-87 yteJ S RDD family
CMLFLONI_03017 5.1e-179 sppA OU signal peptide peptidase SppA
CMLFLONI_03018 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CMLFLONI_03019 2.2e-311 ytcJ S amidohydrolase
CMLFLONI_03020 8.6e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CMLFLONI_03021 2e-29 sspB S spore protein
CMLFLONI_03022 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CMLFLONI_03023 5e-207 iscS2 2.8.1.7 E Cysteine desulfurase
CMLFLONI_03024 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
CMLFLONI_03025 4.6e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
CMLFLONI_03026 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
CMLFLONI_03027 1e-108 yttP K Transcriptional regulator
CMLFLONI_03028 2.2e-87 ytsP 1.8.4.14 T GAF domain-containing protein
CMLFLONI_03029 2.4e-311 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
CMLFLONI_03030 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
CMLFLONI_03032 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMLFLONI_03033 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
CMLFLONI_03034 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
CMLFLONI_03035 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
CMLFLONI_03036 6.1e-224 acuC BQ histone deacetylase
CMLFLONI_03037 6.8e-125 motS N Flagellar motor protein
CMLFLONI_03038 6e-146 motA N flagellar motor
CMLFLONI_03039 1.7e-182 ccpA K catabolite control protein A
CMLFLONI_03040 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
CMLFLONI_03041 2.8e-54 ytxJ O Protein of unknown function (DUF2847)
CMLFLONI_03042 6.6e-17 ytxH S COG4980 Gas vesicle protein
CMLFLONI_03043 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
CMLFLONI_03044 4.8e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
CMLFLONI_03045 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
CMLFLONI_03046 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
CMLFLONI_03047 9.8e-149 ytpQ S Belongs to the UPF0354 family
CMLFLONI_03048 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
CMLFLONI_03049 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
CMLFLONI_03050 2.6e-205 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
CMLFLONI_03051 2.2e-51 ytzB S small secreted protein
CMLFLONI_03052 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
CMLFLONI_03053 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
CMLFLONI_03054 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
CMLFLONI_03055 7.8e-45 ytzH S YtzH-like protein
CMLFLONI_03056 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
CMLFLONI_03057 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
CMLFLONI_03058 2.5e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
CMLFLONI_03059 1.3e-165 ytlQ
CMLFLONI_03060 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
CMLFLONI_03061 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
CMLFLONI_03062 2.3e-270 pepV 3.5.1.18 E Dipeptidase
CMLFLONI_03063 7.2e-226 pbuO S permease
CMLFLONI_03064 6e-200 ythQ U Bacterial ABC transporter protein EcsB
CMLFLONI_03065 4.8e-131 ythP V ABC transporter
CMLFLONI_03066 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
CMLFLONI_03067 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
CMLFLONI_03068 2.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_03069 4.9e-241 ytfP S HI0933-like protein
CMLFLONI_03070 8.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
CMLFLONI_03071 3.1e-26 yteV S Sporulation protein Cse60
CMLFLONI_03072 2.6e-115 yteU S Integral membrane protein
CMLFLONI_03073 5e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
CMLFLONI_03074 3.9e-72 yteS G transport
CMLFLONI_03075 1.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
CMLFLONI_03076 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
CMLFLONI_03077 0.0 ytdP K Transcriptional regulator
CMLFLONI_03078 4.4e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
CMLFLONI_03079 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
CMLFLONI_03080 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
CMLFLONI_03081 1.6e-216 bioI 1.14.14.46 C Cytochrome P450
CMLFLONI_03082 7.1e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
CMLFLONI_03083 1.6e-123 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
CMLFLONI_03084 4.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
CMLFLONI_03085 1.3e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
CMLFLONI_03086 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
CMLFLONI_03087 6e-171 ytaP S Acetyl xylan esterase (AXE1)
CMLFLONI_03088 1.5e-189 msmR K Transcriptional regulator
CMLFLONI_03089 2.1e-246 msmE G Bacterial extracellular solute-binding protein
CMLFLONI_03090 6.2e-168 amyD P ABC transporter
CMLFLONI_03091 4.4e-144 amyC P ABC transporter (permease)
CMLFLONI_03092 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
CMLFLONI_03093 8.1e-51 ytwF P Sulfurtransferase
CMLFLONI_03094 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
CMLFLONI_03095 7.7e-55 ytvB S Protein of unknown function (DUF4257)
CMLFLONI_03096 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
CMLFLONI_03097 1.3e-210 yttB EGP Major facilitator Superfamily
CMLFLONI_03098 3.3e-42 yttA 2.7.13.3 S Pfam Transposase IS66
CMLFLONI_03099 0.0 bceB V ABC transporter (permease)
CMLFLONI_03100 4.3e-138 bceA V ABC transporter, ATP-binding protein
CMLFLONI_03101 1.2e-185 T PhoQ Sensor
CMLFLONI_03102 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_03103 5.5e-234 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
CMLFLONI_03104 9.1e-127 ytrE V ABC transporter, ATP-binding protein
CMLFLONI_03105 1.6e-148
CMLFLONI_03106 4.7e-153 P ABC-2 family transporter protein
CMLFLONI_03107 4.2e-161 ytrB P abc transporter atp-binding protein
CMLFLONI_03108 5.1e-66 ytrA K GntR family transcriptional regulator
CMLFLONI_03110 6.7e-41 ytzC S Protein of unknown function (DUF2524)
CMLFLONI_03111 4.4e-188 yhcC S Fe-S oxidoreductase
CMLFLONI_03112 2.4e-104 ytqB J Putative rRNA methylase
CMLFLONI_03113 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
CMLFLONI_03114 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
CMLFLONI_03115 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CMLFLONI_03116 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_03117 0.0 asnB 6.3.5.4 E Asparagine synthase
CMLFLONI_03118 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
CMLFLONI_03119 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
CMLFLONI_03120 1.2e-38 ytmB S Protein of unknown function (DUF2584)
CMLFLONI_03121 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
CMLFLONI_03122 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
CMLFLONI_03123 1.4e-144 ytlC P ABC transporter
CMLFLONI_03124 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
CMLFLONI_03125 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
CMLFLONI_03126 7e-63 ytkC S Bacteriophage holin family
CMLFLONI_03127 2.1e-76 dps P Belongs to the Dps family
CMLFLONI_03129 2.4e-72 ytkA S YtkA-like
CMLFLONI_03130 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
CMLFLONI_03131 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CMLFLONI_03132 3.6e-41 rpmE2 J Ribosomal protein L31
CMLFLONI_03133 3.1e-248 cydA 1.10.3.14 C oxidase, subunit
CMLFLONI_03134 3.6e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
CMLFLONI_03135 1.1e-24 S Domain of Unknown Function (DUF1540)
CMLFLONI_03136 7.5e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
CMLFLONI_03137 1.5e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
CMLFLONI_03138 1e-139 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
CMLFLONI_03139 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
CMLFLONI_03140 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
CMLFLONI_03141 2.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
CMLFLONI_03142 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
CMLFLONI_03143 7.4e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
CMLFLONI_03144 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CMLFLONI_03145 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
CMLFLONI_03146 1.3e-131 dksA T COG1734 DnaK suppressor protein
CMLFLONI_03147 8.7e-153 galU 2.7.7.9 M Nucleotidyl transferase
CMLFLONI_03148 5.4e-242 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CMLFLONI_03149 3.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
CMLFLONI_03150 1.7e-232 ytcC M Glycosyltransferase Family 4
CMLFLONI_03152 2.2e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
CMLFLONI_03153 6.9e-217 cotSA M Glycosyl transferases group 1
CMLFLONI_03154 4.4e-205 cotI S Spore coat protein
CMLFLONI_03155 1.2e-74 tspO T membrane
CMLFLONI_03156 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
CMLFLONI_03157 7.1e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
CMLFLONI_03158 8.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
CMLFLONI_03159 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
CMLFLONI_03160 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
CMLFLONI_03169 7.8e-08
CMLFLONI_03170 1.3e-09
CMLFLONI_03177 2e-08
CMLFLONI_03182 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
CMLFLONI_03183 5.5e-92 M1-753 M FR47-like protein
CMLFLONI_03184 2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
CMLFLONI_03185 2.7e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
CMLFLONI_03186 3.9e-84 yuaE S DinB superfamily
CMLFLONI_03187 3.9e-107 yuaD
CMLFLONI_03188 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
CMLFLONI_03189 1.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
CMLFLONI_03190 5.5e-95 yuaC K Belongs to the GbsR family
CMLFLONI_03191 2.2e-91 yuaB
CMLFLONI_03192 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
CMLFLONI_03193 2.7e-236 ktrB P Potassium
CMLFLONI_03194 1e-38 yiaA S yiaA/B two helix domain
CMLFLONI_03195 1.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMLFLONI_03196 6.2e-277 yubD P Major Facilitator Superfamily
CMLFLONI_03197 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
CMLFLONI_03199 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
CMLFLONI_03200 9.1e-196 yubA S transporter activity
CMLFLONI_03201 9.7e-183 ygjR S Oxidoreductase
CMLFLONI_03202 2.6e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
CMLFLONI_03203 7.2e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
CMLFLONI_03204 3.3e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
CMLFLONI_03205 6.6e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
CMLFLONI_03206 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
CMLFLONI_03207 5.1e-239 mcpA NT chemotaxis protein
CMLFLONI_03208 1.6e-293 mcpA NT chemotaxis protein
CMLFLONI_03209 1.4e-220 mcpA NT chemotaxis protein
CMLFLONI_03210 3.2e-225 mcpA NT chemotaxis protein
CMLFLONI_03211 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
CMLFLONI_03212 1e-35
CMLFLONI_03213 2.1e-72 yugU S Uncharacterised protein family UPF0047
CMLFLONI_03214 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
CMLFLONI_03215 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
CMLFLONI_03216 1.4e-116 yugP S Zn-dependent protease
CMLFLONI_03217 4.6e-39
CMLFLONI_03218 1.1e-53 mstX S Membrane-integrating protein Mistic
CMLFLONI_03219 1.7e-182 yugO P COG1226 Kef-type K transport systems
CMLFLONI_03220 1.3e-72 yugN S YugN-like family
CMLFLONI_03222 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
CMLFLONI_03223 4e-228 yugK C Dehydrogenase
CMLFLONI_03224 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
CMLFLONI_03225 1.1e-34 yuzA S Domain of unknown function (DUF378)
CMLFLONI_03226 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
CMLFLONI_03227 2.1e-199 yugH 2.6.1.1 E Aminotransferase
CMLFLONI_03228 1.6e-85 alaR K Transcriptional regulator
CMLFLONI_03229 4.9e-156 yugF I Hydrolase
CMLFLONI_03230 4.6e-39 yugE S Domain of unknown function (DUF1871)
CMLFLONI_03231 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
CMLFLONI_03232 1.3e-232 T PhoQ Sensor
CMLFLONI_03233 7.4e-70 kapB G Kinase associated protein B
CMLFLONI_03234 4.2e-115 kapD L the KinA pathway to sporulation
CMLFLONI_03236 4.2e-184 yuxJ EGP Major facilitator Superfamily
CMLFLONI_03237 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
CMLFLONI_03238 9.1e-74 yuxK S protein conserved in bacteria
CMLFLONI_03239 6.3e-78 yufK S Family of unknown function (DUF5366)
CMLFLONI_03240 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
CMLFLONI_03241 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
CMLFLONI_03242 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
CMLFLONI_03243 1.9e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
CMLFLONI_03244 2.1e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
CMLFLONI_03245 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
CMLFLONI_03246 8.2e-233 maeN C COG3493 Na citrate symporter
CMLFLONI_03247 5e-15
CMLFLONI_03248 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
CMLFLONI_03249 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CMLFLONI_03250 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CMLFLONI_03251 5.4e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CMLFLONI_03252 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CMLFLONI_03253 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
CMLFLONI_03254 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
CMLFLONI_03255 5.1e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
CMLFLONI_03256 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_03257 0.0 comP 2.7.13.3 T Histidine kinase
CMLFLONI_03259 1.7e-128 comQ H Belongs to the FPP GGPP synthase family
CMLFLONI_03261 8.5e-23 yuzC
CMLFLONI_03262 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
CMLFLONI_03263 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
CMLFLONI_03264 2.8e-102 pncA Q COG1335 Amidases related to nicotinamidase
CMLFLONI_03265 5.1e-66 yueI S Protein of unknown function (DUF1694)
CMLFLONI_03266 4.8e-38 yueH S YueH-like protein
CMLFLONI_03267 1.7e-31 yueG S Spore germination protein gerPA/gerPF
CMLFLONI_03268 3.2e-190 yueF S transporter activity
CMLFLONI_03269 6.3e-69 S Protein of unknown function (DUF2283)
CMLFLONI_03270 2.9e-24 S Protein of unknown function (DUF2642)
CMLFLONI_03271 4.8e-96 yueE S phosphohydrolase
CMLFLONI_03272 2.2e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_03273 5.6e-64 yueC S Family of unknown function (DUF5383)
CMLFLONI_03274 0.0 esaA S type VII secretion protein EsaA
CMLFLONI_03275 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
CMLFLONI_03276 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
CMLFLONI_03277 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
CMLFLONI_03278 2.8e-45 esxA S Belongs to the WXG100 family
CMLFLONI_03279 1.5e-228 yukF QT Transcriptional regulator
CMLFLONI_03280 1.4e-204 ald 1.4.1.1 E Belongs to the AlaDH PNT family
CMLFLONI_03281 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
CMLFLONI_03282 1.4e-35 mbtH S MbtH-like protein
CMLFLONI_03283 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_03284 2.2e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
CMLFLONI_03285 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
CMLFLONI_03286 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
CMLFLONI_03287 1.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03288 8e-165 besA S Putative esterase
CMLFLONI_03289 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
CMLFLONI_03290 1.1e-93 bioY S Biotin biosynthesis protein
CMLFLONI_03291 3.9e-211 yuiF S antiporter
CMLFLONI_03292 1.3e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
CMLFLONI_03293 1.2e-77 yuiD S protein conserved in bacteria
CMLFLONI_03294 1.4e-116 yuiC S protein conserved in bacteria
CMLFLONI_03295 8.4e-27 yuiB S Putative membrane protein
CMLFLONI_03296 3.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
CMLFLONI_03297 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
CMLFLONI_03299 5.1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
CMLFLONI_03300 3.8e-116 paiB K Putative FMN-binding domain
CMLFLONI_03301 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_03302 3.7e-63 erpA S Belongs to the HesB IscA family
CMLFLONI_03303 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CMLFLONI_03304 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CMLFLONI_03305 3.2e-39 yuzB S Belongs to the UPF0349 family
CMLFLONI_03306 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
CMLFLONI_03307 3e-56 yuzD S protein conserved in bacteria
CMLFLONI_03308 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
CMLFLONI_03309 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
CMLFLONI_03310 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
CMLFLONI_03311 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CMLFLONI_03312 7.9e-241 hom 1.1.1.3 E homoserine dehydrogenase
CMLFLONI_03313 6.5e-198 yutH S Spore coat protein
CMLFLONI_03314 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
CMLFLONI_03315 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
CMLFLONI_03316 1e-75 yutE S Protein of unknown function DUF86
CMLFLONI_03317 9.7e-48 yutD S protein conserved in bacteria
CMLFLONI_03318 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
CMLFLONI_03319 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CMLFLONI_03320 4.5e-196 lytH M Peptidase, M23
CMLFLONI_03321 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
CMLFLONI_03322 1.1e-47 yunC S Domain of unknown function (DUF1805)
CMLFLONI_03323 9.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
CMLFLONI_03324 1e-140 yunE S membrane transporter protein
CMLFLONI_03325 7.3e-171 yunF S Protein of unknown function DUF72
CMLFLONI_03326 8.2e-60 yunG
CMLFLONI_03327 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
CMLFLONI_03328 7e-300 pucR QT COG2508 Regulator of polyketide synthase expression
CMLFLONI_03329 2e-234 pbuX F Permease family
CMLFLONI_03330 4.8e-222 pbuX F xanthine
CMLFLONI_03331 5.8e-280 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
CMLFLONI_03332 1.7e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
CMLFLONI_03334 1.5e-94 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
CMLFLONI_03335 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
CMLFLONI_03336 2.9e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
CMLFLONI_03337 5.3e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
CMLFLONI_03338 3.8e-187 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
CMLFLONI_03340 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
CMLFLONI_03341 2.3e-237 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
CMLFLONI_03342 7.7e-168 bsn L Ribonuclease
CMLFLONI_03343 5.9e-205 msmX P Belongs to the ABC transporter superfamily
CMLFLONI_03344 1.1e-135 yurK K UTRA
CMLFLONI_03345 1.1e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
CMLFLONI_03346 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
CMLFLONI_03347 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
CMLFLONI_03348 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
CMLFLONI_03349 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
CMLFLONI_03350 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
CMLFLONI_03351 5.2e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
CMLFLONI_03353 1.8e-41
CMLFLONI_03354 2.9e-66 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_03355 7.9e-271 sufB O FeS cluster assembly
CMLFLONI_03356 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
CMLFLONI_03357 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CMLFLONI_03358 1.4e-245 sufD O assembly protein SufD
CMLFLONI_03359 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
CMLFLONI_03360 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CMLFLONI_03361 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
CMLFLONI_03362 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
CMLFLONI_03363 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CMLFLONI_03364 2.4e-56 yusD S SCP-2 sterol transfer family
CMLFLONI_03365 5.6e-55 traF CO Thioredoxin
CMLFLONI_03366 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
CMLFLONI_03367 1.1e-39 yusG S Protein of unknown function (DUF2553)
CMLFLONI_03368 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
CMLFLONI_03369 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
CMLFLONI_03370 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
CMLFLONI_03371 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
CMLFLONI_03372 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
CMLFLONI_03373 4.7e-09 S YuzL-like protein
CMLFLONI_03374 2.2e-165 fadM E Proline dehydrogenase
CMLFLONI_03375 5.1e-40
CMLFLONI_03376 3.2e-53 yusN M Coat F domain
CMLFLONI_03377 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
CMLFLONI_03378 3.8e-293 yusP P Major facilitator superfamily
CMLFLONI_03379 8.4e-66 yusQ S Tautomerase enzyme
CMLFLONI_03380 2.5e-62 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03381 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03382 2.7e-160 yusT K LysR substrate binding domain
CMLFLONI_03383 3.8e-47 yusU S Protein of unknown function (DUF2573)
CMLFLONI_03384 1e-153 yusV 3.6.3.34 HP ABC transporter
CMLFLONI_03385 5.6e-66 S YusW-like protein
CMLFLONI_03386 3.2e-301 pepF2 E COG1164 Oligoendopeptidase F
CMLFLONI_03387 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03388 1.2e-79 dps P Ferritin-like domain
CMLFLONI_03389 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMLFLONI_03390 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_03391 1.7e-249 cssS 2.7.13.3 T PhoQ Sensor
CMLFLONI_03392 4.3e-158 yuxN K Transcriptional regulator
CMLFLONI_03393 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
CMLFLONI_03394 2.3e-24 S Protein of unknown function (DUF3970)
CMLFLONI_03395 3.7e-247 gerAA EG Spore germination protein
CMLFLONI_03396 9.1e-198 gerAB E Spore germination protein
CMLFLONI_03397 6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
CMLFLONI_03398 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_03399 5.5e-187 vraS 2.7.13.3 T Histidine kinase
CMLFLONI_03400 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
CMLFLONI_03401 9.3e-129 liaG S Putative adhesin
CMLFLONI_03402 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
CMLFLONI_03403 5.6e-62 liaI S membrane
CMLFLONI_03404 7e-226 yvqJ EGP Major facilitator Superfamily
CMLFLONI_03405 1.3e-99 yvqK 2.5.1.17 S Adenosyltransferase
CMLFLONI_03406 3.6e-241 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
CMLFLONI_03407 1.9e-184 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_03408 2.2e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
CMLFLONI_03409 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03410 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
CMLFLONI_03411 0.0 T PhoQ Sensor
CMLFLONI_03412 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_03413 7.2e-23
CMLFLONI_03414 2.1e-97 yvrI K RNA polymerase
CMLFLONI_03415 6.9e-19 S YvrJ protein family
CMLFLONI_03416 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
CMLFLONI_03417 1.3e-64 yvrL S Regulatory protein YrvL
CMLFLONI_03418 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
CMLFLONI_03419 2.3e-122 macB V ABC transporter, ATP-binding protein
CMLFLONI_03420 1.4e-175 M Efflux transporter rnd family, mfp subunit
CMLFLONI_03421 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
CMLFLONI_03422 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_03423 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CMLFLONI_03424 2e-177 fhuD P ABC transporter
CMLFLONI_03426 4.9e-236 yvsH E Arginine ornithine antiporter
CMLFLONI_03427 6.5e-16 S Small spore protein J (Spore_SspJ)
CMLFLONI_03428 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
CMLFLONI_03429 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
CMLFLONI_03430 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
CMLFLONI_03431 6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
CMLFLONI_03432 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
CMLFLONI_03433 1.1e-155 yvgN S reductase
CMLFLONI_03434 5.4e-86 yvgO
CMLFLONI_03435 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
CMLFLONI_03436 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
CMLFLONI_03437 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CMLFLONI_03438 0.0 helD 3.6.4.12 L DNA helicase
CMLFLONI_03440 1.6e-106 yvgT S membrane
CMLFLONI_03441 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
CMLFLONI_03442 1e-103 bdbD O Thioredoxin
CMLFLONI_03443 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
CMLFLONI_03444 0.0 copA 3.6.3.54 P P-type ATPase
CMLFLONI_03445 5.9e-29 copZ P Copper resistance protein CopZ
CMLFLONI_03446 2.2e-48 csoR S transcriptional
CMLFLONI_03447 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
CMLFLONI_03448 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CMLFLONI_03449 0.0 yvaC S Fusaric acid resistance protein-like
CMLFLONI_03450 2.8e-72 yvaD S Family of unknown function (DUF5360)
CMLFLONI_03451 3.4e-53 yvaE P Small Multidrug Resistance protein
CMLFLONI_03452 3.3e-98 K Bacterial regulatory proteins, tetR family
CMLFLONI_03453 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03454 1.8e-15
CMLFLONI_03457 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
CMLFLONI_03458 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
CMLFLONI_03459 5.6e-143 est 3.1.1.1 S Carboxylesterase
CMLFLONI_03460 2.4e-23 secG U Preprotein translocase subunit SecG
CMLFLONI_03461 8.2e-153 yvaM S Serine aminopeptidase, S33
CMLFLONI_03462 9.8e-36 yvzC K Transcriptional
CMLFLONI_03463 1.2e-68 K transcriptional
CMLFLONI_03464 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
CMLFLONI_03465 2.2e-54 yodB K transcriptional
CMLFLONI_03466 3.2e-218 NT chemotaxis protein
CMLFLONI_03467 2.5e-152 T His Kinase A (phosphoacceptor) domain
CMLFLONI_03468 2.5e-105 K Transcriptional regulatory protein, C terminal
CMLFLONI_03469 1.7e-81 mutG S ABC-2 family transporter protein
CMLFLONI_03470 1.5e-87 spaE S ABC-2 family transporter protein
CMLFLONI_03471 4.2e-103 mutF V ABC transporter, ATP-binding protein
CMLFLONI_03473 1.1e-09 S Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores
CMLFLONI_03474 9.3e-96 spaC2 V PFAM Lanthionine synthetase
CMLFLONI_03475 1.3e-156 spaT V ABC transporter
CMLFLONI_03476 1.3e-196 spaB S Lantibiotic dehydratase, C terminus
CMLFLONI_03477 4.7e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CMLFLONI_03478 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMLFLONI_03479 3.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CMLFLONI_03480 1.2e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CMLFLONI_03481 2.1e-62 yvbF K Belongs to the GbsR family
CMLFLONI_03482 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
CMLFLONI_03483 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
CMLFLONI_03484 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
CMLFLONI_03485 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
CMLFLONI_03486 3.5e-97 yvbF K Belongs to the GbsR family
CMLFLONI_03487 2.8e-90 yvbG U UPF0056 membrane protein
CMLFLONI_03488 1.9e-112 yvbH S YvbH-like oligomerisation region
CMLFLONI_03489 1.2e-121 exoY M Membrane
CMLFLONI_03490 6.8e-251 tcaA S response to antibiotic
CMLFLONI_03491 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
CMLFLONI_03492 1.9e-242 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
CMLFLONI_03493 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
CMLFLONI_03494 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
CMLFLONI_03495 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
CMLFLONI_03496 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
CMLFLONI_03497 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CMLFLONI_03498 1.6e-252 araE EGP Major facilitator Superfamily
CMLFLONI_03499 5.5e-203 araR K transcriptional
CMLFLONI_03500 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_03501 5.1e-159 yvbU K Transcriptional regulator
CMLFLONI_03502 1.6e-155 yvbV EG EamA-like transporter family
CMLFLONI_03503 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
CMLFLONI_03504 1.6e-191 yvbX S Glycosyl hydrolase
CMLFLONI_03505 3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CMLFLONI_03506 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
CMLFLONI_03507 3.4e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
CMLFLONI_03508 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_03509 8.9e-201 desK 2.7.13.3 T Histidine kinase
CMLFLONI_03510 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
CMLFLONI_03511 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
CMLFLONI_03512 2.6e-157 rsbQ S Alpha/beta hydrolase family
CMLFLONI_03513 1.4e-199 rsbU 3.1.3.3 T response regulator
CMLFLONI_03514 2.6e-252 galA 3.2.1.89 G arabinogalactan
CMLFLONI_03515 0.0 lacA 3.2.1.23 G beta-galactosidase
CMLFLONI_03516 7.2e-150 ganQ P transport
CMLFLONI_03517 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
CMLFLONI_03518 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
CMLFLONI_03519 1.4e-184 lacR K Transcriptional regulator
CMLFLONI_03520 1e-112 yvfI K COG2186 Transcriptional regulators
CMLFLONI_03521 4.8e-307 yvfH C L-lactate permease
CMLFLONI_03522 9.7e-239 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
CMLFLONI_03523 1e-31 yvfG S YvfG protein
CMLFLONI_03524 3.5e-185 yvfF GM Exopolysaccharide biosynthesis protein
CMLFLONI_03525 2.2e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
CMLFLONI_03526 1.7e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
CMLFLONI_03527 5.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CMLFLONI_03528 1.2e-256 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_03529 1.2e-194 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_03530 1.6e-202 epsI GM pyruvyl transferase
CMLFLONI_03531 8.9e-195 epsH GT2 S Glycosyltransferase like family 2
CMLFLONI_03532 4.8e-207 epsG S EpsG family
CMLFLONI_03533 8.4e-218 epsF GT4 M Glycosyl transferases group 1
CMLFLONI_03534 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
CMLFLONI_03535 1.2e-219 epsD GT4 M Glycosyl transferase 4-like
CMLFLONI_03536 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
CMLFLONI_03537 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
CMLFLONI_03538 1.3e-117 ywqC M biosynthesis protein
CMLFLONI_03539 2.8e-76 slr K transcriptional
CMLFLONI_03540 2.4e-286 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
CMLFLONI_03542 4.6e-93 padC Q Phenolic acid decarboxylase
CMLFLONI_03543 9.3e-72 MA20_18690 S Protein of unknown function (DUF3237)
CMLFLONI_03544 5.8e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
CMLFLONI_03545 8.4e-262 pbpE V Beta-lactamase
CMLFLONI_03546 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
CMLFLONI_03547 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
CMLFLONI_03548 1.8e-295 yveA E amino acid
CMLFLONI_03549 2.6e-106 yvdT K Transcriptional regulator
CMLFLONI_03550 1.5e-50 ykkC P Small Multidrug Resistance protein
CMLFLONI_03551 4.1e-50 sugE P Small Multidrug Resistance protein
CMLFLONI_03552 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
CMLFLONI_03554 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
CMLFLONI_03555 9.1e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
CMLFLONI_03556 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
CMLFLONI_03557 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
CMLFLONI_03558 8.3e-157 malA S Protein of unknown function (DUF1189)
CMLFLONI_03559 9.5e-147 malD P transport
CMLFLONI_03560 5.9e-244 malC P COG1175 ABC-type sugar transport systems, permease components
CMLFLONI_03561 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
CMLFLONI_03562 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
CMLFLONI_03563 8.8e-173 yvdE K Transcriptional regulator
CMLFLONI_03564 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
CMLFLONI_03565 3.4e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
CMLFLONI_03566 2.6e-286 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
CMLFLONI_03567 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
CMLFLONI_03568 4.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CMLFLONI_03569 0.0 yxdM V ABC transporter (permease)
CMLFLONI_03570 7.3e-141 yvcR V ABC transporter, ATP-binding protein
CMLFLONI_03571 1.5e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
CMLFLONI_03572 8.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_03573 3.3e-32
CMLFLONI_03574 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
CMLFLONI_03575 1.6e-36 crh G Phosphocarrier protein Chr
CMLFLONI_03576 1.4e-170 whiA K May be required for sporulation
CMLFLONI_03577 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
CMLFLONI_03578 5.7e-166 rapZ S Displays ATPase and GTPase activities
CMLFLONI_03579 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
CMLFLONI_03580 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
CMLFLONI_03581 2.4e-102 usp CBM50 M protein conserved in bacteria
CMLFLONI_03582 2.4e-278 S COG0457 FOG TPR repeat
CMLFLONI_03583 0.0 msbA2 3.6.3.44 V ABC transporter
CMLFLONI_03585 0.0
CMLFLONI_03586 9.9e-76
CMLFLONI_03587 8.3e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
CMLFLONI_03588 4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
CMLFLONI_03589 8.4e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
CMLFLONI_03590 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CMLFLONI_03591 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
CMLFLONI_03592 2.2e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CMLFLONI_03593 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
CMLFLONI_03594 5e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
CMLFLONI_03595 3.8e-139 yvpB NU protein conserved in bacteria
CMLFLONI_03596 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
CMLFLONI_03597 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
CMLFLONI_03598 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
CMLFLONI_03599 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
CMLFLONI_03600 1.6e-146 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
CMLFLONI_03601 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
CMLFLONI_03602 3.5e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
CMLFLONI_03603 3.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
CMLFLONI_03604 8.9e-133 yvoA K transcriptional
CMLFLONI_03605 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
CMLFLONI_03606 9.5e-72 adcR K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_03607 3.9e-173 cypX 1.14.15.13 C Cytochrome P450
CMLFLONI_03608 1.2e-34 cypX 1.14.15.13 C Cytochrome P450
CMLFLONI_03609 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
CMLFLONI_03610 2e-86 yvmB K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_03611 2.7e-203 yvmA EGP Major facilitator Superfamily
CMLFLONI_03612 1.2e-50 yvlD S Membrane
CMLFLONI_03613 2.6e-26 pspB KT PspC domain
CMLFLONI_03614 2.4e-166 yvlB S Putative adhesin
CMLFLONI_03615 1.8e-48 yvlA
CMLFLONI_03616 5.7e-33 yvkN
CMLFLONI_03617 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMLFLONI_03618 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
CMLFLONI_03619 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
CMLFLONI_03620 1.2e-30 csbA S protein conserved in bacteria
CMLFLONI_03621 0.0 yvkC 2.7.9.2 GT Phosphotransferase
CMLFLONI_03622 2.7e-100 yvkB K Transcriptional regulator
CMLFLONI_03623 1.3e-225 yvkA EGP Major facilitator Superfamily
CMLFLONI_03624 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMLFLONI_03625 5.3e-56 swrA S Swarming motility protein
CMLFLONI_03626 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
CMLFLONI_03627 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
CMLFLONI_03628 1.6e-123 ftsE D cell division ATP-binding protein FtsE
CMLFLONI_03629 1e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
CMLFLONI_03630 7.9e-141 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
CMLFLONI_03631 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CMLFLONI_03632 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
CMLFLONI_03633 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CMLFLONI_03634 1.8e-65
CMLFLONI_03635 1.9e-08 fliT S bacterial-type flagellum organization
CMLFLONI_03636 2.9e-69 fliS N flagellar protein FliS
CMLFLONI_03637 3.7e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
CMLFLONI_03638 6.1e-57 flaG N flagellar protein FlaG
CMLFLONI_03639 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
CMLFLONI_03640 9.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
CMLFLONI_03641 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
CMLFLONI_03642 2.2e-49 yviE
CMLFLONI_03643 7.8e-155 flgL N Belongs to the bacterial flagellin family
CMLFLONI_03644 1.2e-264 flgK N flagellar hook-associated protein
CMLFLONI_03645 4.1e-78 flgN NOU FlgN protein
CMLFLONI_03646 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
CMLFLONI_03647 7e-74 yvyF S flagellar protein
CMLFLONI_03648 1.2e-126 comFC S Phosphoribosyl transferase domain
CMLFLONI_03649 5.7e-46 comFB S Late competence development protein ComFB
CMLFLONI_03650 2e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
CMLFLONI_03651 2.1e-154 degV S protein conserved in bacteria
CMLFLONI_03652 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
CMLFLONI_03653 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
CMLFLONI_03654 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
CMLFLONI_03655 6e-163 yvhJ K Transcriptional regulator
CMLFLONI_03656 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
CMLFLONI_03657 9.5e-233 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
CMLFLONI_03658 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
CMLFLONI_03659 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
CMLFLONI_03660 1.8e-262 tuaE M Teichuronic acid biosynthesis protein
CMLFLONI_03661 2.6e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CMLFLONI_03662 3.8e-218 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
CMLFLONI_03663 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
CMLFLONI_03664 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
CMLFLONI_03665 2.1e-93 M Glycosyltransferase like family 2
CMLFLONI_03666 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
CMLFLONI_03667 0.0 lytB 3.5.1.28 D Stage II sporulation protein
CMLFLONI_03668 1e-11
CMLFLONI_03669 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
CMLFLONI_03670 2.7e-216 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
CMLFLONI_03671 2.1e-88 M Glycosyltransferase like family 2
CMLFLONI_03672 2.3e-98 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
CMLFLONI_03673 1.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
CMLFLONI_03674 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
CMLFLONI_03675 4.9e-269 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
CMLFLONI_03676 1e-132 tagG GM Transport permease protein
CMLFLONI_03677 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMLFLONI_03678 5.3e-240 ggaA M Glycosyltransferase like family 2
CMLFLONI_03679 1.1e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CMLFLONI_03680 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
CMLFLONI_03681 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
CMLFLONI_03682 1.9e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CMLFLONI_03683 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
CMLFLONI_03684 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
CMLFLONI_03685 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMLFLONI_03686 2e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
CMLFLONI_03687 8.9e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
CMLFLONI_03688 3.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
CMLFLONI_03689 3.7e-263 gerBA EG Spore germination protein
CMLFLONI_03690 4e-193 gerBB E Spore germination protein
CMLFLONI_03691 2.7e-205 gerAC S Spore germination protein
CMLFLONI_03692 1.2e-247 ywtG EGP Major facilitator Superfamily
CMLFLONI_03693 2.3e-168 ywtF K Transcriptional regulator
CMLFLONI_03694 2.7e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
CMLFLONI_03695 3.5e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
CMLFLONI_03696 3.6e-21 ywtC
CMLFLONI_03697 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
CMLFLONI_03698 8.6e-70 pgsC S biosynthesis protein
CMLFLONI_03699 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
CMLFLONI_03700 3.6e-177 rbsR K transcriptional
CMLFLONI_03701 2.7e-160 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CMLFLONI_03702 1.4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
CMLFLONI_03703 2.5e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
CMLFLONI_03704 1.2e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
CMLFLONI_03705 2.4e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
CMLFLONI_03706 8.7e-93 batE T Sh3 type 3 domain protein
CMLFLONI_03707 8e-48 ywsA S Protein of unknown function (DUF3892)
CMLFLONI_03708 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
CMLFLONI_03709 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
CMLFLONI_03710 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
CMLFLONI_03711 4.2e-127 alsR K LysR substrate binding domain
CMLFLONI_03712 2.9e-30 alsR K LysR substrate binding domain
CMLFLONI_03713 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CMLFLONI_03714 1.7e-122 ywrJ
CMLFLONI_03715 9.3e-124 cotB
CMLFLONI_03716 6.2e-207 cotH M Spore Coat
CMLFLONI_03717 1.3e-12
CMLFLONI_03718 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CMLFLONI_03719 8.7e-51 S Domain of unknown function (DUF4181)
CMLFLONI_03720 3e-303 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
CMLFLONI_03721 8e-82 ywrC K Transcriptional regulator
CMLFLONI_03722 1.2e-103 ywrB P Chromate transporter
CMLFLONI_03723 1.3e-88 ywrA P COG2059 Chromate transport protein ChrA
CMLFLONI_03724 8.7e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
CMLFLONI_03725 1.7e-25
CMLFLONI_03726 7.1e-243 ywqJ S Pre-toxin TG
CMLFLONI_03727 1.3e-38 ywqI S Family of unknown function (DUF5344)
CMLFLONI_03728 9.7e-23 S Domain of unknown function (DUF5082)
CMLFLONI_03729 5.4e-152 ywqG S Domain of unknown function (DUF1963)
CMLFLONI_03730 1.5e-247 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
CMLFLONI_03731 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
CMLFLONI_03732 2.5e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
CMLFLONI_03733 2e-116 ywqC M biosynthesis protein
CMLFLONI_03734 1.2e-17
CMLFLONI_03735 4.6e-307 ywqB S SWIM zinc finger
CMLFLONI_03736 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
CMLFLONI_03737 1.8e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
CMLFLONI_03738 3.4e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
CMLFLONI_03739 3.7e-57 ssbB L Single-stranded DNA-binding protein
CMLFLONI_03740 1.3e-66 ywpG
CMLFLONI_03741 1.1e-66 ywpF S YwpF-like protein
CMLFLONI_03742 6.7e-84 srtA 3.4.22.70 M Sortase family
CMLFLONI_03743 0.0 M1-568 M cell wall anchor domain
CMLFLONI_03744 3.1e-174 M1-574 T Transcriptional regulatory protein, C terminal
CMLFLONI_03745 0.0 ywpD T PhoQ Sensor
CMLFLONI_03746 1.3e-48 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
CMLFLONI_03747 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
CMLFLONI_03748 4.4e-197 S aspartate phosphatase
CMLFLONI_03749 2.6e-141 flhP N flagellar basal body
CMLFLONI_03750 1.5e-125 flhO N flagellar basal body
CMLFLONI_03751 3.5e-180 mbl D Rod shape-determining protein
CMLFLONI_03752 3e-44 spoIIID K Stage III sporulation protein D
CMLFLONI_03753 2.1e-70 ywoH K COG1846 Transcriptional regulators
CMLFLONI_03754 2.7e-211 ywoG EGP Major facilitator Superfamily
CMLFLONI_03755 1.4e-230 ywoF P Right handed beta helix region
CMLFLONI_03756 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
CMLFLONI_03757 2.8e-241 ywoD EGP Major facilitator superfamily
CMLFLONI_03758 4e-104 phzA Q Isochorismatase family
CMLFLONI_03759 2.2e-76
CMLFLONI_03760 4.3e-225 amt P Ammonium transporter
CMLFLONI_03761 1.6e-58 nrgB K Belongs to the P(II) protein family
CMLFLONI_03762 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
CMLFLONI_03763 1.6e-70 ywnJ S VanZ like family
CMLFLONI_03764 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
CMLFLONI_03765 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
CMLFLONI_03766 5.7e-09 ywnC S Family of unknown function (DUF5362)
CMLFLONI_03767 2.2e-70 ywnF S Family of unknown function (DUF5392)
CMLFLONI_03768 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMLFLONI_03769 2.6e-143 mta K transcriptional
CMLFLONI_03770 1.7e-58 ywnC S Family of unknown function (DUF5362)
CMLFLONI_03771 5.8e-112 ywnB S NAD(P)H-binding
CMLFLONI_03772 1.7e-64 ywnA K Transcriptional regulator
CMLFLONI_03773 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
CMLFLONI_03774 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
CMLFLONI_03775 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
CMLFLONI_03776 3.2e-10 csbD K CsbD-like
CMLFLONI_03777 3e-84 ywmF S Peptidase M50
CMLFLONI_03778 1.3e-103 S response regulator aspartate phosphatase
CMLFLONI_03779 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CMLFLONI_03780 3.8e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CMLFLONI_03782 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
CMLFLONI_03783 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
CMLFLONI_03784 1e-174 spoIID D Stage II sporulation protein D
CMLFLONI_03785 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMLFLONI_03786 1.3e-131 ywmB S TATA-box binding
CMLFLONI_03787 2.1e-32 ywzB S membrane
CMLFLONI_03788 4.8e-87 ywmA
CMLFLONI_03789 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
CMLFLONI_03790 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
CMLFLONI_03791 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
CMLFLONI_03792 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
CMLFLONI_03793 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMLFLONI_03794 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
CMLFLONI_03795 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
CMLFLONI_03796 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
CMLFLONI_03797 2.5e-62 atpI S ATP synthase
CMLFLONI_03798 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
CMLFLONI_03799 1.3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
CMLFLONI_03800 7.2e-95 ywlG S Belongs to the UPF0340 family
CMLFLONI_03801 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
CMLFLONI_03802 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CMLFLONI_03803 1.7e-91 mntP P Probably functions as a manganese efflux pump
CMLFLONI_03804 3.8e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
CMLFLONI_03805 4.7e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
CMLFLONI_03806 2.6e-110 spoIIR S stage II sporulation protein R
CMLFLONI_03807 8.3e-55 ywlA S Uncharacterised protein family (UPF0715)
CMLFLONI_03809 1.5e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
CMLFLONI_03810 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
CMLFLONI_03811 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_03812 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
CMLFLONI_03813 8.6e-160 ywkB S Membrane transport protein
CMLFLONI_03814 0.0 sfcA 1.1.1.38 C malic enzyme
CMLFLONI_03815 5.4e-104 tdk 2.7.1.21 F thymidine kinase
CMLFLONI_03816 1.1e-32 rpmE J Binds the 23S rRNA
CMLFLONI_03817 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
CMLFLONI_03818 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
CMLFLONI_03819 1.6e-21 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMLFLONI_03820 2.5e-200 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CMLFLONI_03821 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CMLFLONI_03822 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
CMLFLONI_03823 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
CMLFLONI_03824 2.3e-90 ywjG S Domain of unknown function (DUF2529)
CMLFLONI_03825 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
CMLFLONI_03826 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
CMLFLONI_03827 1.1e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
CMLFLONI_03828 0.0 fadF C COG0247 Fe-S oxidoreductase
CMLFLONI_03829 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
CMLFLONI_03830 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
CMLFLONI_03831 2.7e-42 ywjC
CMLFLONI_03832 4.8e-96 ywjB H RibD C-terminal domain
CMLFLONI_03833 0.0 ywjA V ABC transporter
CMLFLONI_03834 1.9e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CMLFLONI_03835 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
CMLFLONI_03836 2.4e-93 narJ 1.7.5.1 C nitrate reductase
CMLFLONI_03837 2.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
CMLFLONI_03838 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CMLFLONI_03839 1.6e-85 arfM T cyclic nucleotide binding
CMLFLONI_03840 1.7e-139 ywiC S YwiC-like protein
CMLFLONI_03841 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
CMLFLONI_03842 2.3e-213 narK P COG2223 Nitrate nitrite transporter
CMLFLONI_03843 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
CMLFLONI_03844 4.7e-73 ywiB S protein conserved in bacteria
CMLFLONI_03845 1e-07 S Bacteriocin subtilosin A
CMLFLONI_03846 4.9e-270 C Fe-S oxidoreductases
CMLFLONI_03848 3.3e-132 cbiO V ABC transporter
CMLFLONI_03849 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
CMLFLONI_03850 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
CMLFLONI_03851 1.3e-248 L Peptidase, M16
CMLFLONI_03853 1.9e-245 ywhL CO amine dehydrogenase activity
CMLFLONI_03854 2.5e-205 ywhK CO amine dehydrogenase activity
CMLFLONI_03855 2.3e-79 S aspartate phosphatase
CMLFLONI_03858 1.7e-20
CMLFLONI_03861 1.4e-57 V ATPases associated with a variety of cellular activities
CMLFLONI_03863 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
CMLFLONI_03864 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
CMLFLONI_03865 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
CMLFLONI_03866 8.9e-95 ywhD S YwhD family
CMLFLONI_03867 5.1e-119 ywhC S Peptidase family M50
CMLFLONI_03868 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
CMLFLONI_03869 9.5e-71 ywhA K Transcriptional regulator
CMLFLONI_03870 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
CMLFLONI_03872 2e-237 mmr U Major Facilitator Superfamily
CMLFLONI_03873 1.5e-77 yffB K Transcriptional regulator
CMLFLONI_03874 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
CMLFLONI_03875 8.7e-256 ywfO S COG1078 HD superfamily phosphohydrolases
CMLFLONI_03876 3.1e-36 ywzC S Belongs to the UPF0741 family
CMLFLONI_03877 5.1e-110 rsfA_1
CMLFLONI_03878 5.5e-153 ywfM EG EamA-like transporter family
CMLFLONI_03879 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
CMLFLONI_03880 9.2e-164 cysL K Transcriptional regulator
CMLFLONI_03881 1.6e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
CMLFLONI_03882 3.3e-146 ywfI C May function as heme-dependent peroxidase
CMLFLONI_03883 1.9e-136 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_03884 2.3e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
CMLFLONI_03885 7.3e-209 bacE EGP Major facilitator Superfamily
CMLFLONI_03886 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
CMLFLONI_03887 1.1e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
CMLFLONI_03888 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
CMLFLONI_03889 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
CMLFLONI_03890 1.3e-205 ywfA EGP Major facilitator Superfamily
CMLFLONI_03891 3.7e-249 lysP E amino acid
CMLFLONI_03892 0.0 rocB E arginine degradation protein
CMLFLONI_03893 2.3e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
CMLFLONI_03894 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
CMLFLONI_03895 1.2e-77
CMLFLONI_03896 1.3e-86 spsL 5.1.3.13 M Spore Coat
CMLFLONI_03897 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
CMLFLONI_03898 5.1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
CMLFLONI_03899 3.5e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CMLFLONI_03900 1e-187 spsG M Spore Coat
CMLFLONI_03901 3.5e-129 spsF M Spore Coat
CMLFLONI_03902 3.5e-213 spsE 2.5.1.56 M acid synthase
CMLFLONI_03903 1.2e-163 spsD 2.3.1.210 K Spore Coat
CMLFLONI_03904 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
CMLFLONI_03905 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
CMLFLONI_03906 2.6e-143 spsA M Spore Coat
CMLFLONI_03907 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
CMLFLONI_03908 4.3e-59 ywdK S small membrane protein
CMLFLONI_03909 8.3e-238 ywdJ F Xanthine uracil
CMLFLONI_03910 1.5e-47 ywdI S Family of unknown function (DUF5327)
CMLFLONI_03911 1.6e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CMLFLONI_03912 3.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
CMLFLONI_03913 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
CMLFLONI_03915 1.4e-113 ywdD
CMLFLONI_03916 1.3e-57 pex K Transcriptional regulator PadR-like family
CMLFLONI_03917 3.9e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
CMLFLONI_03918 2e-28 ywdA
CMLFLONI_03919 2e-290 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
CMLFLONI_03920 1.8e-251 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_03921 2.3e-139 focA P Formate/nitrite transporter
CMLFLONI_03922 7e-150 sacT K transcriptional antiterminator
CMLFLONI_03924 0.0 vpr O Belongs to the peptidase S8 family
CMLFLONI_03925 1.1e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_03926 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
CMLFLONI_03927 2.9e-202 rodA D Belongs to the SEDS family
CMLFLONI_03928 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
CMLFLONI_03929 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CMLFLONI_03930 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
CMLFLONI_03931 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CMLFLONI_03932 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
CMLFLONI_03933 1e-35 ywzA S membrane
CMLFLONI_03934 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
CMLFLONI_03935 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CMLFLONI_03936 9.5e-60 gtcA S GtrA-like protein
CMLFLONI_03937 2.2e-122 ywcC K transcriptional regulator
CMLFLONI_03939 9.8e-49 ywcB S Protein of unknown function, DUF485
CMLFLONI_03940 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CMLFLONI_03941 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
CMLFLONI_03942 3.2e-223 ywbN P Dyp-type peroxidase family protein
CMLFLONI_03943 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
CMLFLONI_03944 3.2e-251 P COG0672 High-affinity Fe2 Pb2 permease
CMLFLONI_03945 7.2e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
CMLFLONI_03946 8.2e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
CMLFLONI_03947 4.3e-153 ywbI K Transcriptional regulator
CMLFLONI_03948 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
CMLFLONI_03949 2.3e-111 ywbG M effector of murein hydrolase
CMLFLONI_03950 1.2e-206 ywbF EGP Major facilitator Superfamily
CMLFLONI_03951 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
CMLFLONI_03952 4.1e-220 ywbD 2.1.1.191 J Methyltransferase
CMLFLONI_03953 4.4e-67 ywbC 4.4.1.5 E glyoxalase
CMLFLONI_03954 6.4e-246 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLFLONI_03955 9.9e-272 epr 3.4.21.62 O Belongs to the peptidase S8 family
CMLFLONI_03956 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_03957 1.2e-152 sacY K transcriptional antiterminator
CMLFLONI_03958 4.5e-168 gspA M General stress
CMLFLONI_03959 5.1e-125 ywaF S Integral membrane protein
CMLFLONI_03960 2e-86 ywaE K Transcriptional regulator
CMLFLONI_03961 1.3e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CMLFLONI_03962 1.2e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
CMLFLONI_03963 1e-92 K Helix-turn-helix XRE-family like proteins
CMLFLONI_03964 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
CMLFLONI_03965 9.8e-129 ynfM EGP Major facilitator Superfamily
CMLFLONI_03966 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
CMLFLONI_03967 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
CMLFLONI_03968 1.1e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_03969 1.2e-232 dltB M membrane protein involved in D-alanine export
CMLFLONI_03970 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_03971 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
CMLFLONI_03972 4.7e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_03973 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
CMLFLONI_03974 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
CMLFLONI_03975 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
CMLFLONI_03976 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
CMLFLONI_03977 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
CMLFLONI_03978 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
CMLFLONI_03979 1.1e-19 yxzF
CMLFLONI_03980 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
CMLFLONI_03981 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
CMLFLONI_03982 2.9e-213 yxlH EGP Major facilitator Superfamily
CMLFLONI_03983 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
CMLFLONI_03984 4.4e-166 yxlF V ABC transporter, ATP-binding protein
CMLFLONI_03985 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
CMLFLONI_03986 2.2e-28
CMLFLONI_03987 8.1e-46 yxlC S Family of unknown function (DUF5345)
CMLFLONI_03988 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
CMLFLONI_03989 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
CMLFLONI_03990 1.6e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CMLFLONI_03991 0.0 cydD V ATP-binding protein
CMLFLONI_03992 1.4e-309 cydD V ATP-binding
CMLFLONI_03993 2.5e-189 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
CMLFLONI_03994 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
CMLFLONI_03995 2.7e-228 cimH C COG3493 Na citrate symporter
CMLFLONI_03996 2.3e-311 3.4.24.84 O Peptidase family M48
CMLFLONI_03998 3.6e-154 yxkH G Polysaccharide deacetylase
CMLFLONI_03999 5.9e-205 msmK P Belongs to the ABC transporter superfamily
CMLFLONI_04000 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
CMLFLONI_04001 4.1e-270 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CMLFLONI_04002 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
CMLFLONI_04003 4.1e-73 yxkC S Domain of unknown function (DUF4352)
CMLFLONI_04004 1.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
CMLFLONI_04005 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
CMLFLONI_04006 9.6e-166 yxjO K LysR substrate binding domain
CMLFLONI_04007 2.4e-78 S Protein of unknown function (DUF1453)
CMLFLONI_04008 4.9e-192 yxjM T Signal transduction histidine kinase
CMLFLONI_04009 4.1e-113 K helix_turn_helix, Lux Regulon
CMLFLONI_04010 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
CMLFLONI_04012 6e-85 yxjI S LURP-one-related
CMLFLONI_04013 9.7e-219 yxjG 2.1.1.14 E Methionine synthase
CMLFLONI_04014 3.7e-218 yxjG 2.1.1.14 E Methionine synthase
CMLFLONI_04015 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
CMLFLONI_04016 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
CMLFLONI_04017 1.2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CMLFLONI_04018 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
CMLFLONI_04019 3.9e-156 rlmA 2.1.1.187 Q Methyltransferase domain
CMLFLONI_04020 1.6e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CMLFLONI_04021 2.2e-101 T Domain of unknown function (DUF4163)
CMLFLONI_04022 5.7e-21 yxiS
CMLFLONI_04023 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
CMLFLONI_04024 6.6e-224 citH C Citrate transporter
CMLFLONI_04025 5e-144 exoK GH16 M licheninase activity
CMLFLONI_04026 8.3e-151 licT K transcriptional antiterminator
CMLFLONI_04027 6.6e-114
CMLFLONI_04028 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
CMLFLONI_04029 1.9e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
CMLFLONI_04030 8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
CMLFLONI_04033 7.7e-43 yxiJ S YxiJ-like protein
CMLFLONI_04034 4.3e-83 yxiI S Protein of unknown function (DUF2716)
CMLFLONI_04035 1e-135
CMLFLONI_04036 8.3e-13 yxiG
CMLFLONI_04037 7.6e-16 yxiG
CMLFLONI_04038 0.0 wapA M COG3209 Rhs family protein
CMLFLONI_04039 1.6e-163 yxxF EG EamA-like transporter family
CMLFLONI_04040 1.1e-72 yxiE T Belongs to the universal stress protein A family
CMLFLONI_04041 4.6e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMLFLONI_04042 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
CMLFLONI_04043 5.5e-53
CMLFLONI_04044 8.3e-136 S nuclease activity
CMLFLONI_04046 7.3e-19 S Protein conserved in bacteria
CMLFLONI_04048 3e-125 S nuclease activity
CMLFLONI_04049 1.4e-38 yxiC S Family of unknown function (DUF5344)
CMLFLONI_04050 2.3e-20 S Domain of unknown function (DUF5082)
CMLFLONI_04051 1.6e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
CMLFLONI_04052 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
CMLFLONI_04053 6.8e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
CMLFLONI_04054 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
CMLFLONI_04055 3.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
CMLFLONI_04056 2.2e-179 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
CMLFLONI_04057 2.3e-251 lysP E amino acid
CMLFLONI_04058 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
CMLFLONI_04059 1.7e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
CMLFLONI_04060 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
CMLFLONI_04061 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
CMLFLONI_04062 4.4e-152 yxxB S Domain of Unknown Function (DUF1206)
CMLFLONI_04063 6e-197 eutH E Ethanolamine utilisation protein, EutH
CMLFLONI_04064 4.4e-247 yxeQ S MmgE/PrpD family
CMLFLONI_04065 3e-212 yxeP 3.5.1.47 E hydrolase activity
CMLFLONI_04066 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
CMLFLONI_04067 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
CMLFLONI_04068 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
CMLFLONI_04069 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
CMLFLONI_04070 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CMLFLONI_04071 2.9e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
CMLFLONI_04072 5.2e-150 yidA S hydrolases of the HAD superfamily
CMLFLONI_04075 1.3e-20 yxeE
CMLFLONI_04076 5.6e-16 yxeD
CMLFLONI_04077 8.5e-69
CMLFLONI_04078 2.5e-175 fhuD P ABC transporter
CMLFLONI_04079 1.5e-58 yxeA S Protein of unknown function (DUF1093)
CMLFLONI_04080 0.0 yxdM V ABC transporter (permease)
CMLFLONI_04081 9.4e-141 yxdL V ABC transporter, ATP-binding protein
CMLFLONI_04082 4e-181 T PhoQ Sensor
CMLFLONI_04083 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_04084 4.6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
CMLFLONI_04085 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
CMLFLONI_04086 8.6e-167 iolH G Xylose isomerase-like TIM barrel
CMLFLONI_04087 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
CMLFLONI_04088 6.2e-233 iolF EGP Major facilitator Superfamily
CMLFLONI_04089 8e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
CMLFLONI_04090 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
CMLFLONI_04091 7.1e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
CMLFLONI_04092 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
CMLFLONI_04093 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
CMLFLONI_04094 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
CMLFLONI_04095 8.3e-176 iolS C Aldo keto reductase
CMLFLONI_04097 8.3e-48 yxcD S Protein of unknown function (DUF2653)
CMLFLONI_04098 2.8e-244 csbC EGP Major facilitator Superfamily
CMLFLONI_04099 0.0 htpG O Molecular chaperone. Has ATPase activity
CMLFLONI_04101 2.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
CMLFLONI_04102 2.7e-208 yxbF K Bacterial regulatory proteins, tetR family
CMLFLONI_04103 1.3e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
CMLFLONI_04104 4e-12 yxaI S membrane protein domain
CMLFLONI_04105 9.9e-92 S PQQ-like domain
CMLFLONI_04106 7.2e-60 S Family of unknown function (DUF5391)
CMLFLONI_04107 1.4e-75 yxaI S membrane protein domain
CMLFLONI_04108 1.5e-222 P Protein of unknown function (DUF418)
CMLFLONI_04109 2.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
CMLFLONI_04110 7.1e-101 yxaF K Transcriptional regulator
CMLFLONI_04111 2.1e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
CMLFLONI_04112 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
CMLFLONI_04113 4.9e-48 S LrgA family
CMLFLONI_04114 3.8e-117 yxaC M effector of murein hydrolase
CMLFLONI_04115 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
CMLFLONI_04116 1.8e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
CMLFLONI_04117 7.3e-127 gntR K transcriptional
CMLFLONI_04118 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
CMLFLONI_04119 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
CMLFLONI_04120 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CMLFLONI_04121 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
CMLFLONI_04122 3.8e-287 ahpF O Alkyl hydroperoxide reductase
CMLFLONI_04123 5.6e-189 wgaE S Polysaccharide pyruvyl transferase
CMLFLONI_04124 2.7e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
CMLFLONI_04125 3.7e-32 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
CMLFLONI_04126 7.1e-127 yydK K Transcriptional regulator
CMLFLONI_04127 7.6e-13
CMLFLONI_04128 1.6e-118 S ABC-2 family transporter protein
CMLFLONI_04129 1e-108 prrC P ABC transporter
CMLFLONI_04130 1.6e-132 yydH O Peptidase M50
CMLFLONI_04131 1.1e-183 S Radical SAM superfamily
CMLFLONI_04132 8e-12
CMLFLONI_04133 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
CMLFLONI_04135 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
CMLFLONI_04136 1.1e-09 S YyzF-like protein
CMLFLONI_04137 3.8e-64
CMLFLONI_04138 1.5e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
CMLFLONI_04140 1.5e-31 yycQ S Protein of unknown function (DUF2651)
CMLFLONI_04141 2.3e-207 yycP
CMLFLONI_04142 4.2e-130 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
CMLFLONI_04143 3.2e-83 yycN 2.3.1.128 K Acetyltransferase
CMLFLONI_04144 1.5e-187 S aspartate phosphatase
CMLFLONI_04146 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
CMLFLONI_04147 1.3e-260 rocE E amino acid
CMLFLONI_04148 2.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
CMLFLONI_04149 1.3e-257 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
CMLFLONI_04150 3e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CMLFLONI_04151 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
CMLFLONI_04152 7.3e-155 yycI S protein conserved in bacteria
CMLFLONI_04153 4.4e-258 yycH S protein conserved in bacteria
CMLFLONI_04154 0.0 vicK 2.7.13.3 T Histidine kinase
CMLFLONI_04155 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
CMLFLONI_04160 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CMLFLONI_04161 2.6e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_04162 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
CMLFLONI_04163 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
CMLFLONI_04165 1.9e-15 yycC K YycC-like protein
CMLFLONI_04166 8.4e-221 yeaN P COG2807 Cyanate permease
CMLFLONI_04167 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
CMLFLONI_04168 2.2e-73 rplI J binds to the 23S rRNA
CMLFLONI_04169 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
CMLFLONI_04170 2.9e-160 yybS S membrane
CMLFLONI_04172 3.9e-84 cotF M Spore coat protein
CMLFLONI_04173 1.4e-68 ydeP3 K Transcriptional regulator
CMLFLONI_04174 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
CMLFLONI_04175 2.5e-69
CMLFLONI_04177 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
CMLFLONI_04178 1.3e-110 K TipAS antibiotic-recognition domain
CMLFLONI_04179 5.8e-122
CMLFLONI_04180 5.7e-52 yybH S SnoaL-like domain
CMLFLONI_04181 6.6e-127 S Metallo-beta-lactamase superfamily
CMLFLONI_04182 5.6e-77 yybA 2.3.1.57 K transcriptional
CMLFLONI_04183 7.6e-71 yjcF S Acetyltransferase (GNAT) domain
CMLFLONI_04184 6.5e-97 yyaS S Membrane
CMLFLONI_04185 7.6e-94 yyaR K Acetyltransferase (GNAT) domain
CMLFLONI_04186 6.6e-65 yyaQ S YjbR
CMLFLONI_04187 3.8e-107 yyaP 1.5.1.3 H RibD C-terminal domain
CMLFLONI_04188 6.7e-22 yyaR K acetyltransferase
CMLFLONI_04189 1.5e-60 yyaN K MerR HTH family regulatory protein
CMLFLONI_04190 2.9e-157 yyaM EG EamA-like transporter family
CMLFLONI_04191 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
CMLFLONI_04192 8e-168 yyaK S CAAX protease self-immunity
CMLFLONI_04193 7.9e-244 EGP Major facilitator superfamily
CMLFLONI_04194 4.7e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
CMLFLONI_04195 1.5e-67 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
CMLFLONI_04196 1.5e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
CMLFLONI_04197 1.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
CMLFLONI_04198 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
CMLFLONI_04199 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
CMLFLONI_04200 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
CMLFLONI_04201 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
CMLFLONI_04202 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
CMLFLONI_04203 2.3e-33 yyzM S protein conserved in bacteria
CMLFLONI_04204 8.1e-177 yyaD S Membrane
CMLFLONI_04205 2.1e-111 yyaC S Sporulation protein YyaC
CMLFLONI_04206 2.1e-149 spo0J K Belongs to the ParB family
CMLFLONI_04207 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
CMLFLONI_04208 1.5e-74 S Bacterial PH domain
CMLFLONI_04209 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
CMLFLONI_04210 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
CMLFLONI_04211 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
CMLFLONI_04212 1.9e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
CMLFLONI_04213 1.9e-107 jag S single-stranded nucleic acid binding R3H
CMLFLONI_04214 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CMLFLONI_04215 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
CMLFLONI_04216 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CMLFLONI_04217 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
CMLFLONI_04218 2.4e-33 yaaA S S4 domain
CMLFLONI_04219 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
CMLFLONI_04220 1.8e-37 yaaB S Domain of unknown function (DUF370)
CMLFLONI_04221 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMLFLONI_04222 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CMLFLONI_04223 2.4e-306 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_04224 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_04225 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
CMLFLONI_04226 5.2e-20
CMLFLONI_04229 3.4e-39 S COG NOG14552 non supervised orthologous group
CMLFLONI_04234 2e-08
CMLFLONI_04242 2e-08

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)