ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMFPNEFG_00001 1.5e-135 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HMFPNEFG_00002 3.7e-54
HMFPNEFG_00003 9.9e-206 yttB EGP Major facilitator Superfamily
HMFPNEFG_00004 1.5e-234 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMFPNEFG_00005 2e-74 rplI J Binds to the 23S rRNA
HMFPNEFG_00006 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMFPNEFG_00007 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMFPNEFG_00008 1.7e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMFPNEFG_00009 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HMFPNEFG_00010 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMFPNEFG_00011 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMFPNEFG_00012 1.2e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMFPNEFG_00013 1.7e-34 yaaA S S4 domain protein YaaA
HMFPNEFG_00014 6.7e-10 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HMFPNEFG_00015 3.3e-82 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HMFPNEFG_00016 3.2e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMFPNEFG_00017 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMFPNEFG_00018 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMFPNEFG_00019 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMFPNEFG_00020 1.7e-129 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMFPNEFG_00021 9.7e-130 jag S R3H domain protein
HMFPNEFG_00022 4.3e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMFPNEFG_00023 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMFPNEFG_00024 0.0 asnB 6.3.5.4 E Asparagine synthase
HMFPNEFG_00025 5.3e-292 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMFPNEFG_00026 1.9e-247 yxbA 6.3.1.12 S ATP-grasp enzyme
HMFPNEFG_00027 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMFPNEFG_00028 9.1e-89 2.3.1.183 M Acetyltransferase GNAT family
HMFPNEFG_00029 1.8e-161 S reductase
HMFPNEFG_00031 3.6e-288 S amidohydrolase
HMFPNEFG_00032 2.5e-164 K Aminotransferase class I and II
HMFPNEFG_00033 1.4e-119 azlC E azaleucine resistance protein AzlC
HMFPNEFG_00034 7.1e-50 azlD E Branched-chain amino acid transport
HMFPNEFG_00035 6.1e-117 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMFPNEFG_00037 2.7e-70 S GyrI-like small molecule binding domain
HMFPNEFG_00038 6.4e-39 S GyrI-like small molecule binding domain
HMFPNEFG_00039 5e-122 yhiD S MgtC family
HMFPNEFG_00040 3e-93 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMFPNEFG_00041 5.9e-191 V Beta-lactamase
HMFPNEFG_00042 3.9e-27 mleP3 S Membrane transport protein
HMFPNEFG_00043 7.3e-121 T Transcriptional regulatory protein, C terminal
HMFPNEFG_00044 9.9e-239 T GHKL domain
HMFPNEFG_00045 4.7e-109 S Peptidase propeptide and YPEB domain
HMFPNEFG_00046 1.7e-76 P FAD-binding domain
HMFPNEFG_00047 4.3e-55 yphJ 4.1.1.44 S decarboxylase
HMFPNEFG_00048 5.3e-83 K Bacterial regulatory proteins, tetR family
HMFPNEFG_00049 2.2e-77 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMFPNEFG_00050 8.2e-166 K COG COG0846 NAD-dependent protein deacetylases, SIR2 family
HMFPNEFG_00051 7.3e-166 S Oxidoreductase, aldo keto reductase family protein
HMFPNEFG_00052 2.7e-85 C Flavodoxin
HMFPNEFG_00053 5.6e-158 K Transcriptional regulator
HMFPNEFG_00054 6.3e-88 lacA S transferase hexapeptide repeat
HMFPNEFG_00055 9.4e-32 S thiolester hydrolase activity
HMFPNEFG_00056 2e-152 S Alpha beta hydrolase
HMFPNEFG_00057 2.3e-93 padC Q Phenolic acid decarboxylase
HMFPNEFG_00058 3.3e-92 padR K Virulence activator alpha C-term
HMFPNEFG_00059 4.7e-66 GM NAD(P)H-binding
HMFPNEFG_00060 2.3e-155 ypuA S Protein of unknown function (DUF1002)
HMFPNEFG_00061 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
HMFPNEFG_00062 4.3e-59 K Transcriptional regulator
HMFPNEFG_00063 4.3e-40 K Transcriptional regulator
HMFPNEFG_00064 7.6e-163 akr5f 1.1.1.346 S reductase
HMFPNEFG_00065 5.3e-104 K Transcriptional regulator C-terminal region
HMFPNEFG_00066 2.1e-74 S membrane
HMFPNEFG_00067 6.1e-88 S membrane
HMFPNEFG_00068 1.2e-112 GM NAD(P)H-binding
HMFPNEFG_00069 1.1e-64 yneR
HMFPNEFG_00070 3.4e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
HMFPNEFG_00071 3.7e-140 T EAL domain
HMFPNEFG_00072 1.6e-252 pgaC GT2 M Glycosyl transferase
HMFPNEFG_00073 5.2e-84
HMFPNEFG_00074 1.2e-203 2.7.7.65 T GGDEF domain
HMFPNEFG_00075 5e-122 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HMFPNEFG_00076 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMFPNEFG_00077 1.9e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
HMFPNEFG_00078 2e-92 folT S ECF transporter, substrate-specific component
HMFPNEFG_00079 0.0 pepN 3.4.11.2 E aminopeptidase
HMFPNEFG_00080 2e-112 ylbE GM NAD dependent epimerase dehydratase family protein
HMFPNEFG_00081 9.8e-255 pepC 3.4.22.40 E aminopeptidase
HMFPNEFG_00082 6.5e-210 EGP Major facilitator Superfamily
HMFPNEFG_00083 1.8e-229
HMFPNEFG_00084 3.5e-79 K Transcriptional regulator, HxlR family
HMFPNEFG_00085 3.7e-108 XK27_02070 S Nitroreductase family
HMFPNEFG_00086 2.5e-52 hxlR K Transcriptional regulator, HxlR family
HMFPNEFG_00087 3e-119 GM NmrA-like family
HMFPNEFG_00088 1.7e-70 elaA S Gnat family
HMFPNEFG_00089 1.8e-39 S Cytochrome B5
HMFPNEFG_00090 5.4e-09 S Cytochrome B5
HMFPNEFG_00091 7.8e-41 S Cytochrome B5
HMFPNEFG_00092 1.5e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
HMFPNEFG_00094 2.3e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMFPNEFG_00095 2.4e-240 E amino acid
HMFPNEFG_00096 1.8e-214 npp S type I phosphodiesterase nucleotide pyrophosphatase
HMFPNEFG_00097 3.1e-226 yxiO S Vacuole effluxer Atg22 like
HMFPNEFG_00099 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMFPNEFG_00100 3e-34
HMFPNEFG_00101 2.5e-289 mntH P H( )-stimulated, divalent metal cation uptake system
HMFPNEFG_00102 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
HMFPNEFG_00103 2.6e-86 ygfC K transcriptional regulator (TetR family)
HMFPNEFG_00104 2.1e-183 hrtB V ABC transporter permease
HMFPNEFG_00105 1.8e-114 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMFPNEFG_00106 0.0 yhcA V ABC transporter, ATP-binding protein
HMFPNEFG_00107 4.6e-38
HMFPNEFG_00108 3.5e-49 czrA K Transcriptional regulator, ArsR family
HMFPNEFG_00109 4.5e-212 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMFPNEFG_00110 5.1e-173 scrR K Transcriptional regulator, LacI family
HMFPNEFG_00111 3e-24
HMFPNEFG_00112 8.2e-103
HMFPNEFG_00113 2.6e-214 yttB EGP Major facilitator Superfamily
HMFPNEFG_00114 5.7e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMFPNEFG_00115 2.2e-87
HMFPNEFG_00116 3.5e-109 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HMFPNEFG_00117 2.5e-261 S Putative peptidoglycan binding domain
HMFPNEFG_00118 1.4e-124 yciB M ErfK YbiS YcfS YnhG
HMFPNEFG_00120 2.5e-101
HMFPNEFG_00121 1e-218 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMFPNEFG_00122 5.5e-126 S Alpha beta hydrolase
HMFPNEFG_00123 1.7e-207 gldA 1.1.1.6 C dehydrogenase
HMFPNEFG_00124 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMFPNEFG_00125 1.3e-41
HMFPNEFG_00126 8e-125 pgm3 3.1.3.73 G phosphoglycerate mutase family
HMFPNEFG_00127 4e-284 S C4-dicarboxylate anaerobic carrier
HMFPNEFG_00128 1.8e-251 nhaC C Na H antiporter NhaC
HMFPNEFG_00129 1.6e-241 pbuX F xanthine permease
HMFPNEFG_00130 1.4e-283 pipD E Dipeptidase
HMFPNEFG_00131 1.6e-305 L Transposase
HMFPNEFG_00132 2.2e-168 corA P CorA-like Mg2+ transporter protein
HMFPNEFG_00133 4.5e-166 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMFPNEFG_00134 2.3e-131 terC P membrane
HMFPNEFG_00135 2.1e-54 trxA O Belongs to the thioredoxin family
HMFPNEFG_00136 2.4e-119 mepA V MATE efflux family protein
HMFPNEFG_00137 6.2e-255 S Uncharacterised protein family (UPF0236)
HMFPNEFG_00138 3.1e-108 mepA V MATE efflux family protein
HMFPNEFG_00139 7.2e-55 M Leucine-rich repeat (LRR) protein
HMFPNEFG_00140 6.8e-56 K Transcriptional regulator, ArsR family
HMFPNEFG_00141 1.2e-92 P Cadmium resistance transporter
HMFPNEFG_00142 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
HMFPNEFG_00143 1.6e-152 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMFPNEFG_00144 2.2e-182 ABC-SBP S ABC transporter
HMFPNEFG_00145 1.5e-72 M PFAM NLP P60 protein
HMFPNEFG_00147 1.8e-137 L hmm pf00665
HMFPNEFG_00148 3.4e-53 L Helix-turn-helix domain
HMFPNEFG_00149 4.1e-31
HMFPNEFG_00150 7.8e-272 S ABC transporter, ATP-binding protein
HMFPNEFG_00151 2.3e-142 S Putative ABC-transporter type IV
HMFPNEFG_00152 2e-106 NU mannosyl-glycoprotein
HMFPNEFG_00153 3.2e-248 brnQ U Component of the transport system for branched-chain amino acids
HMFPNEFG_00154 1.5e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
HMFPNEFG_00155 7.6e-205 nrnB S DHHA1 domain
HMFPNEFG_00156 6.9e-49
HMFPNEFG_00157 2.9e-27 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMFPNEFG_00158 2.6e-98 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMFPNEFG_00159 2e-15 S Domain of unknown function (DUF4767)
HMFPNEFG_00160 9.5e-55
HMFPNEFG_00161 5.4e-116 yrkL S Flavodoxin-like fold
HMFPNEFG_00163 1.6e-64 yeaO S Protein of unknown function, DUF488
HMFPNEFG_00164 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMFPNEFG_00165 3e-204 3.1.3.1 S associated with various cellular activities
HMFPNEFG_00166 5.4e-242 S Putative metallopeptidase domain
HMFPNEFG_00167 5.1e-47
HMFPNEFG_00168 0.0 pepO 3.4.24.71 O Peptidase family M13
HMFPNEFG_00169 8.4e-111 K Helix-turn-helix domain
HMFPNEFG_00170 6e-88 ymdB S Macro domain protein
HMFPNEFG_00171 1.6e-197 EGP Major facilitator Superfamily
HMFPNEFG_00172 2.1e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMFPNEFG_00173 5.3e-20 K helix_turn_helix, mercury resistance
HMFPNEFG_00174 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMFPNEFG_00175 1.9e-152 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HMFPNEFG_00176 1.6e-194 ysaB V FtsX-like permease family
HMFPNEFG_00177 2.4e-132 ysaB V FtsX-like permease family
HMFPNEFG_00178 2.6e-135 macB2 V ABC transporter, ATP-binding protein
HMFPNEFG_00179 2.6e-180 T PhoQ Sensor
HMFPNEFG_00180 1.2e-123 K response regulator
HMFPNEFG_00181 3.5e-157 ytbE 1.1.1.346 S Aldo keto reductase
HMFPNEFG_00182 8.9e-136 pnuC H nicotinamide mononucleotide transporter
HMFPNEFG_00183 9.8e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMFPNEFG_00184 2.3e-204
HMFPNEFG_00185 2.6e-52
HMFPNEFG_00186 9.1e-36
HMFPNEFG_00187 4.8e-93 yxkA S Phosphatidylethanolamine-binding protein
HMFPNEFG_00188 4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMFPNEFG_00189 8.6e-184 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HMFPNEFG_00190 1.9e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMFPNEFG_00191 7.6e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMFPNEFG_00192 1.3e-179 galR K Transcriptional regulator
HMFPNEFG_00193 9.5e-96 dedA 3.1.3.1 S SNARE associated Golgi protein
HMFPNEFG_00194 1e-232 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HMFPNEFG_00195 1.5e-80 K AsnC family
HMFPNEFG_00196 1.5e-80 uspA T universal stress protein
HMFPNEFG_00197 1.9e-41 ltrA S Bacterial low temperature requirement A protein (LtrA)
HMFPNEFG_00198 0.0 lacS G Transporter
HMFPNEFG_00199 1.2e-39
HMFPNEFG_00200 3.8e-106 tra L Transposase and inactivated derivatives, IS30 family
HMFPNEFG_00201 3.2e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMFPNEFG_00202 2.2e-287 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMFPNEFG_00203 3.1e-193 yeaN P Transporter, major facilitator family protein
HMFPNEFG_00204 3.2e-74 S 3-demethylubiquinone-9 3-methyltransferase
HMFPNEFG_00205 9.9e-85 nrdI F Belongs to the NrdI family
HMFPNEFG_00206 6.2e-241 yhdP S Transporter associated domain
HMFPNEFG_00207 1.7e-154 ypdB V (ABC) transporter
HMFPNEFG_00208 4.8e-88 GM epimerase
HMFPNEFG_00209 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
HMFPNEFG_00210 2.3e-78 yybA 2.3.1.57 K Transcriptional regulator
HMFPNEFG_00211 4.2e-135 XK27_07210 6.1.1.6 S B3 4 domain
HMFPNEFG_00212 2.8e-170 S AI-2E family transporter
HMFPNEFG_00213 2.9e-159 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HMFPNEFG_00214 2.3e-162
HMFPNEFG_00215 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMFPNEFG_00216 3.7e-190 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMFPNEFG_00217 2.9e-310 lmrA V ABC transporter, ATP-binding protein
HMFPNEFG_00218 0.0 yfiC V ABC transporter
HMFPNEFG_00219 1.1e-283 pipD E Dipeptidase
HMFPNEFG_00220 1.3e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMFPNEFG_00221 1.4e-133 gntR K UbiC transcription regulator-associated domain protein
HMFPNEFG_00222 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMFPNEFG_00223 2.7e-244 yagE E amino acid
HMFPNEFG_00224 8.2e-17 aroD S Serine hydrolase (FSH1)
HMFPNEFG_00225 8e-115 aroD S Serine hydrolase (FSH1)
HMFPNEFG_00226 8.2e-241 brnQ U Component of the transport system for branched-chain amino acids
HMFPNEFG_00227 8.9e-167 GK ROK family
HMFPNEFG_00228 0.0 tetP J elongation factor G
HMFPNEFG_00229 5.1e-81 uspA T universal stress protein
HMFPNEFG_00230 1.1e-194 lplA 6.3.1.20 H Lipoate-protein ligase
HMFPNEFG_00231 7.1e-63
HMFPNEFG_00232 5.2e-14
HMFPNEFG_00233 1.4e-212 EGP Major facilitator Superfamily
HMFPNEFG_00234 1.3e-257 G PTS system Galactitol-specific IIC component
HMFPNEFG_00235 2.6e-180 1.6.5.5 C Zinc-binding dehydrogenase
HMFPNEFG_00236 1.1e-161
HMFPNEFG_00237 1e-72 K Transcriptional regulator
HMFPNEFG_00238 3.7e-190 D Alpha beta
HMFPNEFG_00239 2.2e-52 ypaA S Protein of unknown function (DUF1304)
HMFPNEFG_00240 0.0 yjcE P Sodium proton antiporter
HMFPNEFG_00241 1.6e-52 yvlA
HMFPNEFG_00242 1.8e-113 P Cobalt transport protein
HMFPNEFG_00243 1e-246 cbiO1 S ABC transporter, ATP-binding protein
HMFPNEFG_00244 3e-96 S ABC-type cobalt transport system, permease component
HMFPNEFG_00245 3.3e-133 S membrane transporter protein
HMFPNEFG_00246 2.5e-138 IQ KR domain
HMFPNEFG_00247 3.6e-182 iunH2 3.2.2.1 F nucleoside hydrolase
HMFPNEFG_00248 1.7e-182 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMFPNEFG_00249 6.7e-150 L hmm pf00665
HMFPNEFG_00250 2.5e-127 L Helix-turn-helix domain
HMFPNEFG_00251 5.1e-49 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMFPNEFG_00252 2.7e-117 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HMFPNEFG_00253 2.8e-255 yagE E amino acid
HMFPNEFG_00254 3.4e-85 dps P Belongs to the Dps family
HMFPNEFG_00255 0.0 pacL 3.6.3.8 P P-type ATPase
HMFPNEFG_00256 1.1e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMFPNEFG_00257 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMFPNEFG_00258 5.9e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMFPNEFG_00259 4.5e-146 potB P ABC transporter permease
HMFPNEFG_00260 1.9e-139 potC P ABC transporter permease
HMFPNEFG_00261 4.3e-208 potD P ABC transporter
HMFPNEFG_00262 4e-229
HMFPNEFG_00263 2.5e-56 EGP Sugar (and other) transporter
HMFPNEFG_00264 2.2e-168 EGP Sugar (and other) transporter
HMFPNEFG_00265 3e-254 yfnA E Amino Acid
HMFPNEFG_00266 1.2e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMFPNEFG_00267 1.9e-101 gmk2 2.7.4.8 F Guanylate kinase
HMFPNEFG_00268 7.3e-82 zur P Belongs to the Fur family
HMFPNEFG_00269 4e-17 3.2.1.14 GH18
HMFPNEFG_00270 8.3e-151
HMFPNEFG_00271 5.8e-39 pspC KT PspC domain protein
HMFPNEFG_00272 1.6e-94 K Transcriptional regulator (TetR family)
HMFPNEFG_00273 4.8e-222 V domain protein
HMFPNEFG_00274 7.6e-183 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMFPNEFG_00276 6.6e-35 S Transglycosylase associated protein
HMFPNEFG_00277 7.5e-228 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMFPNEFG_00278 4.2e-126 3.1.3.73 G phosphoglycerate mutase
HMFPNEFG_00279 1.2e-115 dedA S SNARE associated Golgi protein
HMFPNEFG_00280 0.0 helD 3.6.4.12 L DNA helicase
HMFPNEFG_00281 2.8e-36 Q pyridine nucleotide-disulphide oxidoreductase
HMFPNEFG_00282 4.7e-157 EG EamA-like transporter family
HMFPNEFG_00283 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMFPNEFG_00284 4.8e-176 coaA 2.7.1.33 F Pantothenic acid kinase
HMFPNEFG_00285 1.5e-225 S cog cog1373
HMFPNEFG_00287 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMFPNEFG_00288 4.9e-224 oxlT P Major Facilitator Superfamily
HMFPNEFG_00289 1.1e-158 spoU 2.1.1.185 J Methyltransferase
HMFPNEFG_00290 3.6e-111 S Membrane
HMFPNEFG_00291 1.2e-64 O Zinc-dependent metalloprotease
HMFPNEFG_00292 4.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMFPNEFG_00293 1.2e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HMFPNEFG_00295 1.5e-17 NU Mycoplasma protein of unknown function, DUF285
HMFPNEFG_00296 3.3e-87 UW LPXTG-motif cell wall anchor domain protein
HMFPNEFG_00297 0.0 UW LPXTG-motif cell wall anchor domain protein
HMFPNEFG_00298 2e-67 UW LPXTG-motif cell wall anchor domain protein
HMFPNEFG_00299 1.3e-93 L PFAM Integrase catalytic region
HMFPNEFG_00300 1.1e-27 L PFAM Integrase catalytic region
HMFPNEFG_00301 1.7e-183 S Phosphotransferase system, EIIC
HMFPNEFG_00302 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMFPNEFG_00303 1.5e-132 K Transcriptional regulatory protein, C-terminal domain protein
HMFPNEFG_00304 8.6e-159 pstS P Phosphate
HMFPNEFG_00305 2.8e-152 pstC P probably responsible for the translocation of the substrate across the membrane
HMFPNEFG_00306 6.4e-42 pstA P Phosphate transport system permease protein PstA
HMFPNEFG_00307 4.3e-98 pstA P Phosphate transport system permease protein PstA
HMFPNEFG_00308 8.9e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMFPNEFG_00309 1.9e-124 phoU P Plays a role in the regulation of phosphate uptake
HMFPNEFG_00310 4.3e-142
HMFPNEFG_00311 2e-233 ydaM M Glycosyl transferase
HMFPNEFG_00312 7.4e-219 G Glycosyl hydrolases family 8
HMFPNEFG_00313 3.9e-139 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMFPNEFG_00314 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HMFPNEFG_00315 1.7e-238 ktrB P Potassium uptake protein
HMFPNEFG_00316 1.4e-116 ktrA P domain protein
HMFPNEFG_00317 1.2e-81 Q Methyltransferase
HMFPNEFG_00318 7.4e-231 mntH P H( )-stimulated, divalent metal cation uptake system
HMFPNEFG_00319 8.6e-181 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HMFPNEFG_00320 1.5e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HMFPNEFG_00321 8.7e-09 S NADPH-dependent FMN reductase
HMFPNEFG_00322 5.6e-65 S NADPH-dependent FMN reductase
HMFPNEFG_00323 1.4e-20 G Belongs to the glycosyl hydrolase family 6
HMFPNEFG_00324 6.1e-180 MA20_14895 S Conserved hypothetical protein 698
HMFPNEFG_00325 3.9e-133 I alpha/beta hydrolase fold
HMFPNEFG_00326 2e-168 lsa S ABC transporter
HMFPNEFG_00327 9.6e-58 lsa S ABC transporter
HMFPNEFG_00328 2e-180 yfeX P Peroxidase
HMFPNEFG_00329 2.9e-71 arcD S C4-dicarboxylate anaerobic carrier
HMFPNEFG_00330 1.2e-183 arcD S C4-dicarboxylate anaerobic carrier
HMFPNEFG_00331 7.5e-255 ytjP 3.5.1.18 E Dipeptidase
HMFPNEFG_00332 5.3e-215 uhpT EGP Major facilitator Superfamily
HMFPNEFG_00333 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
HMFPNEFG_00334 4.8e-132 ponA V Beta-lactamase enzyme family
HMFPNEFG_00335 8.2e-227 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMFPNEFG_00336 3e-75
HMFPNEFG_00337 3.2e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMFPNEFG_00338 1.5e-25
HMFPNEFG_00339 7.1e-264 S Uncharacterized protein conserved in bacteria (DUF2252)
HMFPNEFG_00340 1.9e-169 L transposase, IS605 OrfB family
HMFPNEFG_00341 4.7e-294 L PFAM plasmid pRiA4b ORF-3 family protein
HMFPNEFG_00342 1.1e-205 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
HMFPNEFG_00343 1e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HMFPNEFG_00344 1.9e-161 mleR K LysR family
HMFPNEFG_00345 2.2e-304 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HMFPNEFG_00346 4.7e-260 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMFPNEFG_00347 1.8e-267 frdC 1.3.5.4 C FAD binding domain
HMFPNEFG_00348 1.3e-252 yflS P Sodium:sulfate symporter transmembrane region
HMFPNEFG_00349 1e-159 mleR K LysR family
HMFPNEFG_00350 2e-250 yjjP S Putative threonine/serine exporter
HMFPNEFG_00351 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMFPNEFG_00352 8.5e-282 emrY EGP Major facilitator Superfamily
HMFPNEFG_00353 3.4e-188 I Alpha beta
HMFPNEFG_00354 2.6e-103 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMFPNEFG_00355 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMFPNEFG_00357 4.6e-160 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HMFPNEFG_00358 9.5e-119 S Domain of unknown function (DUF4811)
HMFPNEFG_00359 1e-268 lmrB EGP Major facilitator Superfamily
HMFPNEFG_00360 4.9e-73 merR K MerR HTH family regulatory protein
HMFPNEFG_00361 2.5e-53
HMFPNEFG_00362 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMFPNEFG_00363 1.1e-217 S CAAX protease self-immunity
HMFPNEFG_00364 1.4e-108 glnP P ABC transporter permease
HMFPNEFG_00365 4.2e-110 gluC P ABC transporter permease
HMFPNEFG_00366 7.5e-152 glnH ET ABC transporter
HMFPNEFG_00367 6.9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMFPNEFG_00368 5.5e-83 usp1 T Belongs to the universal stress protein A family
HMFPNEFG_00369 7.6e-110 S VIT family
HMFPNEFG_00370 5e-117 S membrane
HMFPNEFG_00371 2.6e-166 czcD P cation diffusion facilitator family transporter
HMFPNEFG_00372 1.1e-124 sirR K iron dependent repressor
HMFPNEFG_00373 3.5e-31 cspC K Cold shock protein
HMFPNEFG_00374 3.6e-129 thrE S Putative threonine/serine exporter
HMFPNEFG_00375 6.7e-81 S Threonine/Serine exporter, ThrE
HMFPNEFG_00376 2.7e-120 lssY 3.6.1.27 I phosphatase
HMFPNEFG_00377 3.5e-10 2.3.1.128 J Acetyltransferase (GNAT) domain
HMFPNEFG_00378 1.5e-275 lysP E amino acid
HMFPNEFG_00379 4.3e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMFPNEFG_00385 5.3e-130 S Hydrolases of the alpha beta superfamily
HMFPNEFG_00386 1.3e-16 S Hydrolases of the alpha beta superfamily
HMFPNEFG_00387 1.2e-196 adhP 1.1.1.1 C alcohol dehydrogenase
HMFPNEFG_00388 3.4e-77 ctsR K Belongs to the CtsR family
HMFPNEFG_00389 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMFPNEFG_00390 1e-110 K Bacterial regulatory proteins, tetR family
HMFPNEFG_00391 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMFPNEFG_00392 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMFPNEFG_00393 2.2e-202 ykiI
HMFPNEFG_00394 1.5e-118 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HMFPNEFG_00395 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMFPNEFG_00396 2.4e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMFPNEFG_00397 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMFPNEFG_00398 4.3e-189 L Transposase
HMFPNEFG_00399 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMFPNEFG_00400 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMFPNEFG_00401 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HMFPNEFG_00402 5.7e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMFPNEFG_00403 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMFPNEFG_00404 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMFPNEFG_00405 4.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMFPNEFG_00406 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMFPNEFG_00407 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMFPNEFG_00408 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
HMFPNEFG_00409 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMFPNEFG_00410 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMFPNEFG_00411 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMFPNEFG_00412 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMFPNEFG_00413 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMFPNEFG_00414 1.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMFPNEFG_00415 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMFPNEFG_00416 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMFPNEFG_00417 2.9e-24 rpmD J Ribosomal protein L30
HMFPNEFG_00418 8.9e-64 rplO J Binds to the 23S rRNA
HMFPNEFG_00419 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMFPNEFG_00420 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMFPNEFG_00421 5.9e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMFPNEFG_00422 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMFPNEFG_00423 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMFPNEFG_00424 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMFPNEFG_00425 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMFPNEFG_00426 1.1e-62 rplQ J Ribosomal protein L17
HMFPNEFG_00427 3e-145 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMFPNEFG_00428 1.3e-151 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMFPNEFG_00429 5.7e-141 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMFPNEFG_00430 1.9e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMFPNEFG_00431 4.5e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMFPNEFG_00432 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HMFPNEFG_00433 3.6e-140 IQ reductase
HMFPNEFG_00434 3.6e-114 acmC 3.2.1.96 NU mannosyl-glycoprotein
HMFPNEFG_00435 3e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMFPNEFG_00436 4.3e-211 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMFPNEFG_00437 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMFPNEFG_00438 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMFPNEFG_00439 2.1e-202 camS S sex pheromone
HMFPNEFG_00440 2.4e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMFPNEFG_00441 1e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMFPNEFG_00442 5.4e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMFPNEFG_00443 5.1e-187 yegS 2.7.1.107 G Lipid kinase
HMFPNEFG_00444 2.1e-260 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMFPNEFG_00446 2.1e-28 cspA K Cold shock protein
HMFPNEFG_00448 1.2e-141 L Recombinase
HMFPNEFG_00449 0.0 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
HMFPNEFG_00450 7.9e-35 copZ C Heavy-metal-associated domain
HMFPNEFG_00451 3.9e-93 dps P Belongs to the Dps family
HMFPNEFG_00452 5.8e-112 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HMFPNEFG_00453 3.2e-96 S PFAM Archaeal ATPase
HMFPNEFG_00454 1.3e-46
HMFPNEFG_00456 1.9e-37 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMFPNEFG_00457 7.9e-158 amtB P ammonium transporter
HMFPNEFG_00458 2.1e-249 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
HMFPNEFG_00459 1.4e-90 S B3 4 domain
HMFPNEFG_00460 2.1e-91
HMFPNEFG_00461 4.8e-122 pnb C nitroreductase
HMFPNEFG_00462 2e-74 ogt 2.1.1.63 L Methyltransferase
HMFPNEFG_00463 8.5e-172 XK27_00915 C Luciferase-like monooxygenase
HMFPNEFG_00464 1.5e-153 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HMFPNEFG_00465 7.3e-69 S Protein of unknown function (DUF3021)
HMFPNEFG_00466 6.4e-78 K LytTr DNA-binding domain
HMFPNEFG_00467 9.1e-92 K Acetyltransferase (GNAT) family
HMFPNEFG_00468 3.1e-21
HMFPNEFG_00469 1.1e-119 ybhL S Belongs to the BI1 family
HMFPNEFG_00470 6.5e-81 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HMFPNEFG_00471 9.3e-197 S Protein of unknown function (DUF3114)
HMFPNEFG_00472 3.7e-298 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMFPNEFG_00473 2.2e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMFPNEFG_00474 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HMFPNEFG_00475 9.1e-62 S Domain of unknown function (DUF4828)
HMFPNEFG_00476 4.5e-191 mocA S Oxidoreductase
HMFPNEFG_00477 8.5e-227 yfmL L DEAD DEAH box helicase
HMFPNEFG_00479 2.6e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMFPNEFG_00480 9.3e-56
HMFPNEFG_00481 2.3e-67 gtcA S Teichoic acid glycosylation protein
HMFPNEFG_00482 6.1e-79 fld C Flavodoxin
HMFPNEFG_00483 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
HMFPNEFG_00484 1.7e-220 arcT 2.6.1.1 E Aminotransferase
HMFPNEFG_00485 3.6e-255 E Arginine ornithine antiporter
HMFPNEFG_00486 1.1e-281 yjeM E Amino Acid
HMFPNEFG_00487 3.2e-153 yihY S Belongs to the UPF0761 family
HMFPNEFG_00488 6.6e-34 S Protein of unknown function (DUF2922)
HMFPNEFG_00489 4.9e-31
HMFPNEFG_00490 1.2e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMFPNEFG_00491 4.1e-144 cps1D M Domain of unknown function (DUF4422)
HMFPNEFG_00492 7.3e-172 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMFPNEFG_00493 1.3e-119 rfbP 2.7.8.6 M Bacterial sugar transferase
HMFPNEFG_00494 3.5e-70 cps3F
HMFPNEFG_00495 5.1e-28 M biosynthesis protein
HMFPNEFG_00496 4.2e-76 M Core-2/I-Branching enzyme
HMFPNEFG_00497 4.9e-215 glf 5.4.99.9 M UDP-galactopyranose mutase
HMFPNEFG_00498 1.8e-238 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HMFPNEFG_00499 1.7e-94 GT2 M Glycosyltransferase like family 2
HMFPNEFG_00500 3.9e-76 cps3I G Acyltransferase family
HMFPNEFG_00501 2.2e-50 S Peptidase_C39 like family
HMFPNEFG_00502 6.6e-104 cps3B S Glycosyltransferase like family 2
HMFPNEFG_00504 2.1e-11 L Integrase core domain
HMFPNEFG_00505 8.4e-140 L Integrase core domain
HMFPNEFG_00506 1.7e-79 O Bacterial dnaA protein
HMFPNEFG_00507 2.1e-15 S Psort location CytoplasmicMembrane, score
HMFPNEFG_00508 1.9e-54 M repeat protein
HMFPNEFG_00509 3.6e-20
HMFPNEFG_00510 3.3e-163 yueF S AI-2E family transporter
HMFPNEFG_00511 7.8e-229 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMFPNEFG_00512 5.7e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMFPNEFG_00514 1.1e-62 gntR1 K Transcriptional regulator, GntR family
HMFPNEFG_00515 4.1e-153 V ABC transporter, ATP-binding protein
HMFPNEFG_00516 1.3e-114
HMFPNEFG_00517 3e-141 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HMFPNEFG_00518 7e-99 S Pfam:DUF3816
HMFPNEFG_00519 0.0 clpE O Belongs to the ClpA ClpB family
HMFPNEFG_00520 2.9e-27
HMFPNEFG_00521 2.7e-39 ptsH G phosphocarrier protein HPR
HMFPNEFG_00522 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMFPNEFG_00523 1.4e-226 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HMFPNEFG_00524 7.2e-197 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMFPNEFG_00525 2.5e-178 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMFPNEFG_00526 1.5e-39 ykuJ S Protein of unknown function (DUF1797)
HMFPNEFG_00536 3.5e-97 2.3.1.128 K Acetyltransferase (GNAT) domain
HMFPNEFG_00537 1.5e-237 lmrB EGP Major facilitator Superfamily
HMFPNEFG_00538 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMFPNEFG_00539 3.8e-110 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMFPNEFG_00540 7.5e-150 sufD O Uncharacterized protein family (UPF0051)
HMFPNEFG_00541 2.6e-80 lytE M LysM domain protein
HMFPNEFG_00542 0.0 oppD EP Psort location Cytoplasmic, score
HMFPNEFG_00543 2.3e-93 lytE M LysM domain protein
HMFPNEFG_00544 6e-148 xth 3.1.11.2 L exodeoxyribonuclease III
HMFPNEFG_00545 6.9e-167 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HMFPNEFG_00546 4.5e-236 preA 1.3.1.1 C 4Fe-4S dicluster domain
HMFPNEFG_00547 8.1e-154 yeaE S Aldo keto
HMFPNEFG_00548 2.4e-77 hsp O Belongs to the small heat shock protein (HSP20) family
HMFPNEFG_00549 2.8e-282 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HMFPNEFG_00550 2.9e-78 S Psort location Cytoplasmic, score
HMFPNEFG_00551 7.7e-86 S Short repeat of unknown function (DUF308)
HMFPNEFG_00552 1e-23
HMFPNEFG_00553 2.8e-102 V VanZ like family
HMFPNEFG_00554 4.8e-233 cycA E Amino acid permease
HMFPNEFG_00555 4.3e-85 perR P Belongs to the Fur family
HMFPNEFG_00556 1.5e-253 EGP Major facilitator Superfamily
HMFPNEFG_00557 1.4e-91 tag 3.2.2.20 L glycosylase
HMFPNEFG_00558 5.6e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMFPNEFG_00559 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMFPNEFG_00560 4.9e-41
HMFPNEFG_00561 4.1e-303 ytgP S Polysaccharide biosynthesis protein
HMFPNEFG_00562 6.5e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMFPNEFG_00563 1.1e-277 pepV 3.5.1.18 E dipeptidase PepV
HMFPNEFG_00564 4.3e-86 uspA T Belongs to the universal stress protein A family
HMFPNEFG_00565 1.4e-176 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMFPNEFG_00566 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
HMFPNEFG_00567 3.8e-113
HMFPNEFG_00568 1.6e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
HMFPNEFG_00569 4.4e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMFPNEFG_00570 2.1e-32
HMFPNEFG_00571 4.5e-112 S CAAX protease self-immunity
HMFPNEFG_00572 1.6e-42
HMFPNEFG_00574 2.2e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMFPNEFG_00575 5.2e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HMFPNEFG_00576 1.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HMFPNEFG_00577 4.5e-225 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMFPNEFG_00578 2.8e-105 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HMFPNEFG_00579 6e-216 folP 2.5.1.15 H dihydropteroate synthase
HMFPNEFG_00580 1.8e-43
HMFPNEFG_00581 3.3e-40
HMFPNEFG_00583 1.3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMFPNEFG_00584 7.3e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMFPNEFG_00585 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMFPNEFG_00586 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMFPNEFG_00587 3.5e-40 yheA S Belongs to the UPF0342 family
HMFPNEFG_00588 1.8e-220 yhaO L Ser Thr phosphatase family protein
HMFPNEFG_00589 0.0 L AAA domain
HMFPNEFG_00590 3.4e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMFPNEFG_00592 1.2e-76 hit FG histidine triad
HMFPNEFG_00593 3.9e-136 ecsA V ABC transporter, ATP-binding protein
HMFPNEFG_00594 5.1e-218 ecsB U ABC transporter
HMFPNEFG_00595 1.1e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMFPNEFG_00596 7.7e-27 S YSIRK type signal peptide
HMFPNEFG_00597 2.5e-35 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HMFPNEFG_00598 2.8e-255 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HMFPNEFG_00599 2.3e-145 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HMFPNEFG_00600 1.2e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HMFPNEFG_00601 8.8e-184 iolS C Aldo keto reductase
HMFPNEFG_00602 9.1e-167 glsA 3.5.1.2 E Belongs to the glutaminase family
HMFPNEFG_00603 7.5e-58 ytzB S Small secreted protein
HMFPNEFG_00604 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMFPNEFG_00605 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMFPNEFG_00606 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMFPNEFG_00607 1.5e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMFPNEFG_00608 4.9e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMFPNEFG_00609 1.9e-119 ybhL S Belongs to the BI1 family
HMFPNEFG_00610 4.1e-116 yoaK S Protein of unknown function (DUF1275)
HMFPNEFG_00611 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMFPNEFG_00612 3.7e-159 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMFPNEFG_00613 4.8e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMFPNEFG_00614 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMFPNEFG_00615 1.4e-203 dnaB L replication initiation and membrane attachment
HMFPNEFG_00616 1.1e-170 dnaI L Primosomal protein DnaI
HMFPNEFG_00617 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMFPNEFG_00618 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMFPNEFG_00619 1.6e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMFPNEFG_00620 1.8e-95 yqeG S HAD phosphatase, family IIIA
HMFPNEFG_00621 2.1e-218 yqeH S Ribosome biogenesis GTPase YqeH
HMFPNEFG_00622 1.9e-47 yhbY J RNA-binding protein
HMFPNEFG_00623 5.6e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMFPNEFG_00624 1e-113 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMFPNEFG_00625 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMFPNEFG_00626 1.7e-139 yqeM Q Methyltransferase
HMFPNEFG_00627 2.1e-213 ylbM S Belongs to the UPF0348 family
HMFPNEFG_00628 2.9e-99 yceD S Uncharacterized ACR, COG1399
HMFPNEFG_00629 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMFPNEFG_00630 1.5e-121 K response regulator
HMFPNEFG_00631 9.2e-278 arlS 2.7.13.3 T Histidine kinase
HMFPNEFG_00632 7.4e-267 yjeM E Amino Acid
HMFPNEFG_00633 1.3e-230 V MatE
HMFPNEFG_00634 8.7e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMFPNEFG_00635 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMFPNEFG_00636 7e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMFPNEFG_00637 3.1e-144 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMFPNEFG_00638 3.1e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMFPNEFG_00639 2e-58 yodB K Transcriptional regulator, HxlR family
HMFPNEFG_00640 6.6e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMFPNEFG_00641 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMFPNEFG_00642 5.6e-115 rlpA M PFAM NLP P60 protein
HMFPNEFG_00643 3.3e-118 udk 2.7.1.48 F Cytidine monophosphokinase
HMFPNEFG_00644 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMFPNEFG_00645 8.8e-71 yneR S Belongs to the HesB IscA family
HMFPNEFG_00646 0.0 S membrane
HMFPNEFG_00647 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMFPNEFG_00648 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMFPNEFG_00649 2.6e-100 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMFPNEFG_00650 3.4e-12 gluP 3.4.21.105 S Peptidase, S54 family
HMFPNEFG_00651 3.8e-46 gluP 3.4.21.105 S Peptidase, S54 family
HMFPNEFG_00652 7.4e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HMFPNEFG_00653 7.3e-183 glk 2.7.1.2 G Glucokinase
HMFPNEFG_00654 3.4e-67 yqhL P Rhodanese-like protein
HMFPNEFG_00655 5.9e-22 S Protein of unknown function (DUF3042)
HMFPNEFG_00656 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMFPNEFG_00657 2.4e-261 glnA 6.3.1.2 E glutamine synthetase
HMFPNEFG_00658 3.8e-295 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMFPNEFG_00659 4.8e-221 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMFPNEFG_00660 3.9e-12
HMFPNEFG_00661 9e-153 P Belongs to the nlpA lipoprotein family
HMFPNEFG_00662 1.4e-100 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMFPNEFG_00663 3.7e-51 S Iron-sulfur cluster assembly protein
HMFPNEFG_00664 1e-151
HMFPNEFG_00665 1.5e-173
HMFPNEFG_00666 2.5e-89 dut S Protein conserved in bacteria
HMFPNEFG_00669 8.3e-111 K Transcriptional regulator
HMFPNEFG_00670 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMFPNEFG_00671 1.6e-54 ysxB J Cysteine protease Prp
HMFPNEFG_00672 2.1e-45 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMFPNEFG_00673 2.1e-131 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HMFPNEFG_00674 6.6e-201 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMFPNEFG_00675 1.7e-114 J 2'-5' RNA ligase superfamily
HMFPNEFG_00676 2.2e-70 yqhY S Asp23 family, cell envelope-related function
HMFPNEFG_00677 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMFPNEFG_00678 7.2e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMFPNEFG_00679 5.3e-224 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMFPNEFG_00680 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMFPNEFG_00681 1.7e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMFPNEFG_00682 1.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMFPNEFG_00683 3.3e-77 argR K Regulates arginine biosynthesis genes
HMFPNEFG_00684 1.9e-263 recN L May be involved in recombinational repair of damaged DNA
HMFPNEFG_00685 1.7e-54
HMFPNEFG_00686 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HMFPNEFG_00687 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMFPNEFG_00688 6.9e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMFPNEFG_00689 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMFPNEFG_00690 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMFPNEFG_00691 9.6e-250 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMFPNEFG_00692 2.9e-131 stp 3.1.3.16 T phosphatase
HMFPNEFG_00693 0.0 KLT serine threonine protein kinase
HMFPNEFG_00694 2.8e-165 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMFPNEFG_00695 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMFPNEFG_00696 1.8e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMFPNEFG_00697 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMFPNEFG_00698 4.7e-58 asp S Asp23 family, cell envelope-related function
HMFPNEFG_00699 7.1e-311 yloV S DAK2 domain fusion protein YloV
HMFPNEFG_00700 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMFPNEFG_00701 4e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMFPNEFG_00702 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMFPNEFG_00703 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMFPNEFG_00704 0.0 smc D Required for chromosome condensation and partitioning
HMFPNEFG_00705 4.1e-180 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMFPNEFG_00706 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMFPNEFG_00707 1.8e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMFPNEFG_00708 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMFPNEFG_00709 2e-39 ylqC S Belongs to the UPF0109 family
HMFPNEFG_00710 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMFPNEFG_00711 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMFPNEFG_00712 9.9e-261 yfnA E amino acid
HMFPNEFG_00713 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMFPNEFG_00714 2.9e-34
HMFPNEFG_00715 6.4e-54 S Mazg nucleotide pyrophosphohydrolase
HMFPNEFG_00716 2.8e-159 xth 3.1.11.2 L exodeoxyribonuclease III
HMFPNEFG_00717 4e-63
HMFPNEFG_00718 5.7e-175 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMFPNEFG_00719 1.9e-156 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMFPNEFG_00720 3e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMFPNEFG_00721 2.4e-223 mdtG EGP Major facilitator Superfamily
HMFPNEFG_00722 3.2e-166 T Calcineurin-like phosphoesterase superfamily domain
HMFPNEFG_00723 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMFPNEFG_00725 3e-119 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMFPNEFG_00726 6.5e-138 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMFPNEFG_00727 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
HMFPNEFG_00728 0.0 trxB2 1.8.1.9 C Thioredoxin domain
HMFPNEFG_00729 4.4e-181 M LPXTG-motif cell wall anchor domain protein
HMFPNEFG_00730 0.0 M LPXTG-motif cell wall anchor domain protein
HMFPNEFG_00732 1.2e-11 sraP UW domain, Protein
HMFPNEFG_00733 2.5e-158 L hmm pf00665
HMFPNEFG_00734 4.4e-100 L Helix-turn-helix domain
HMFPNEFG_00735 9e-275 pipD E Dipeptidase
HMFPNEFG_00736 0.0 yjbQ P TrkA C-terminal domain protein
HMFPNEFG_00737 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMFPNEFG_00738 2e-288 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMFPNEFG_00739 1.1e-81
HMFPNEFG_00740 5.5e-30
HMFPNEFG_00741 7.6e-58 K DNA-templated transcription, initiation
HMFPNEFG_00742 1.1e-30 K DNA-templated transcription, initiation
HMFPNEFG_00743 4.2e-127
HMFPNEFG_00744 2.3e-66 K Transcriptional regulator, HxlR family
HMFPNEFG_00745 7.6e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMFPNEFG_00746 1.1e-145 epsB M biosynthesis protein
HMFPNEFG_00747 3.2e-122 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMFPNEFG_00748 9.8e-115 rfbP M Bacterial sugar transferase
HMFPNEFG_00749 6.6e-159 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMFPNEFG_00750 2.1e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HMFPNEFG_00751 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HMFPNEFG_00752 1.8e-83 cps1D M Domain of unknown function (DUF4422)
HMFPNEFG_00753 7.5e-34 M Glycosyltransferase family 92
HMFPNEFG_00754 8.6e-37 GT2 S Glycosyltransferase, group 2 family protein
HMFPNEFG_00755 2.6e-11 S EpsG family
HMFPNEFG_00756 1.9e-50 GT2 M group 2 family protein
HMFPNEFG_00757 4.7e-110 rfbX S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HMFPNEFG_00758 2e-22 GT2 S Glycosyltransferase, group 2 family protein
HMFPNEFG_00759 2.8e-44 S Acyltransferase family
HMFPNEFG_00760 5.8e-216 glf 5.4.99.9 M UDP-galactopyranose mutase
HMFPNEFG_00761 9.6e-155 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HMFPNEFG_00762 2.7e-33 S Protein of unknown function (DUF4065)
HMFPNEFG_00764 1.8e-170 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMFPNEFG_00765 4.5e-250 mmuP E amino acid
HMFPNEFG_00767 9.7e-67 T Toxin-antitoxin system, toxin component, MazF family
HMFPNEFG_00768 1e-37
HMFPNEFG_00770 0.0 snf 2.7.11.1 KL domain protein
HMFPNEFG_00771 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
HMFPNEFG_00772 1.1e-175 M Glycosyl hydrolases family 25
HMFPNEFG_00773 7.6e-208 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HMFPNEFG_00774 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HMFPNEFG_00775 1e-73
HMFPNEFG_00776 3.5e-24
HMFPNEFG_00777 7.8e-106 lssY 3.6.1.27 I Acid phosphatase homologues
HMFPNEFG_00778 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HMFPNEFG_00779 6.3e-227 clcA_2 P Chloride transporter, ClC family
HMFPNEFG_00780 5.7e-115 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HMFPNEFG_00781 2.4e-147 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMFPNEFG_00782 2.1e-138 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HMFPNEFG_00783 5.2e-50
HMFPNEFG_00784 0.0 S SEC-C Motif Domain Protein
HMFPNEFG_00785 2.8e-73
HMFPNEFG_00786 1.5e-175
HMFPNEFG_00787 7.2e-181 fecB P Periplasmic binding protein
HMFPNEFG_00788 1.4e-139 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
HMFPNEFG_00789 1.8e-128 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMFPNEFG_00790 1.5e-77 S Flavodoxin
HMFPNEFG_00791 3.7e-64 moaE 2.8.1.12 H MoaE protein
HMFPNEFG_00792 4.9e-35 moaD 2.8.1.12 H ThiS family
HMFPNEFG_00793 3.9e-218 narK P Transporter, major facilitator family protein
HMFPNEFG_00794 1.2e-152 EG EamA-like transporter family
HMFPNEFG_00795 2.5e-118 L Integrase
HMFPNEFG_00796 1.4e-158 rssA S Phospholipase, patatin family
HMFPNEFG_00797 1.5e-237 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 M Levansucrase/Invertase
HMFPNEFG_00800 9.6e-200 xerS L Belongs to the 'phage' integrase family
HMFPNEFG_00802 6.6e-72 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMFPNEFG_00803 4.2e-77 marR K Transcriptional regulator, MarR family
HMFPNEFG_00804 2.1e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMFPNEFG_00805 6.5e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMFPNEFG_00806 1.2e-158 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMFPNEFG_00807 4.2e-130 IQ reductase
HMFPNEFG_00808 1.2e-225 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMFPNEFG_00809 5.8e-74 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMFPNEFG_00810 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HMFPNEFG_00811 3e-259 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMFPNEFG_00812 5.5e-142 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMFPNEFG_00813 1.1e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMFPNEFG_00814 1.1e-130 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMFPNEFG_00821 1.4e-51
HMFPNEFG_00822 1.5e-112 frnE Q DSBA-like thioredoxin domain
HMFPNEFG_00823 1.7e-78 I alpha/beta hydrolase fold
HMFPNEFG_00824 8.5e-20 K Helix-turn-helix XRE-family like proteins
HMFPNEFG_00825 1.1e-35 S Phage derived protein Gp49-like (DUF891)
HMFPNEFG_00827 1.6e-45 yrvD S Pfam:DUF1049
HMFPNEFG_00828 5.6e-155 3.1.3.102, 3.1.3.104 S hydrolase
HMFPNEFG_00829 8.1e-90 ntd 2.4.2.6 F Nucleoside
HMFPNEFG_00830 1.3e-20
HMFPNEFG_00831 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HMFPNEFG_00832 1.1e-104 yviA S Protein of unknown function (DUF421)
HMFPNEFG_00833 9.1e-72 S Protein of unknown function (DUF3290)
HMFPNEFG_00834 7e-41 ybaN S Protein of unknown function (DUF454)
HMFPNEFG_00835 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMFPNEFG_00836 5.5e-158 endA V DNA/RNA non-specific endonuclease
HMFPNEFG_00837 1e-254 yifK E Amino acid permease
HMFPNEFG_00839 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMFPNEFG_00840 1.3e-229 N Uncharacterized conserved protein (DUF2075)
HMFPNEFG_00841 4.6e-123 S SNARE associated Golgi protein
HMFPNEFG_00842 0.0 uvrA3 L excinuclease ABC, A subunit
HMFPNEFG_00843 9.1e-56 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMFPNEFG_00844 1.2e-59 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMFPNEFG_00845 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HMFPNEFG_00846 8.1e-143 S DUF218 domain
HMFPNEFG_00847 0.0 ubiB S ABC1 family
HMFPNEFG_00848 2.5e-245 yhdP S Transporter associated domain
HMFPNEFG_00849 5e-75 copY K Copper transport repressor CopY TcrY
HMFPNEFG_00850 1.3e-244 EGP Major facilitator Superfamily
HMFPNEFG_00851 1e-73 yeaL S UPF0756 membrane protein
HMFPNEFG_00852 5.6e-79 yphH S Cupin domain
HMFPNEFG_00853 4.7e-82 C Flavodoxin
HMFPNEFG_00854 1.1e-158 K LysR substrate binding domain protein
HMFPNEFG_00855 6.5e-170 1.1.1.346 C Aldo keto reductase
HMFPNEFG_00856 1.8e-38 gcvR T Belongs to the UPF0237 family
HMFPNEFG_00857 5.3e-240 XK27_08635 S UPF0210 protein
HMFPNEFG_00858 1.5e-94 K Acetyltransferase (GNAT) domain
HMFPNEFG_00859 1.2e-160 S Alpha beta hydrolase
HMFPNEFG_00860 1.1e-158 gspA M family 8
HMFPNEFG_00861 2.3e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMFPNEFG_00862 3.8e-93
HMFPNEFG_00863 7.1e-161 degV S EDD domain protein, DegV family
HMFPNEFG_00864 0.0 FbpA K Fibronectin-binding protein
HMFPNEFG_00865 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMFPNEFG_00866 2.1e-207 carA 6.3.5.5 F Belongs to the CarA family
HMFPNEFG_00867 1.1e-172 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMFPNEFG_00868 2.9e-70 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMFPNEFG_00869 1.5e-65 esbA S Family of unknown function (DUF5322)
HMFPNEFG_00870 4.4e-70 rnhA 3.1.26.4 L Ribonuclease HI
HMFPNEFG_00871 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMFPNEFG_00872 1.1e-83 F Belongs to the NrdI family
HMFPNEFG_00873 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMFPNEFG_00874 1.6e-105 ypsA S Belongs to the UPF0398 family
HMFPNEFG_00875 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMFPNEFG_00876 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMFPNEFG_00877 2e-161 EG EamA-like transporter family
HMFPNEFG_00878 3e-125 dnaD L DnaD domain protein
HMFPNEFG_00879 2.9e-85 ypmB S Protein conserved in bacteria
HMFPNEFG_00880 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMFPNEFG_00881 3.3e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HMFPNEFG_00882 4.6e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMFPNEFG_00883 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMFPNEFG_00884 4.9e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMFPNEFG_00885 1.9e-86 S Protein of unknown function (DUF1440)
HMFPNEFG_00886 0.0 rafA 3.2.1.22 G alpha-galactosidase
HMFPNEFG_00887 4.2e-189 galR K Periplasmic binding protein-like domain
HMFPNEFG_00888 1.9e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMFPNEFG_00889 1.2e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMFPNEFG_00890 2.6e-124 lrgB M LrgB-like family
HMFPNEFG_00891 1.9e-66 lrgA S LrgA family
HMFPNEFG_00892 2.4e-130 lytT K response regulator receiver
HMFPNEFG_00893 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
HMFPNEFG_00894 4e-148 f42a O Band 7 protein
HMFPNEFG_00895 6.1e-260 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HMFPNEFG_00896 2.2e-156 yitU 3.1.3.104 S hydrolase
HMFPNEFG_00897 9.2e-39 S Cytochrome B5
HMFPNEFG_00898 9.8e-115 nreC K PFAM regulatory protein LuxR
HMFPNEFG_00899 6.1e-160 hipB K Helix-turn-helix
HMFPNEFG_00900 3.6e-57 yitW S Iron-sulfur cluster assembly protein
HMFPNEFG_00901 1.6e-271 sufB O assembly protein SufB
HMFPNEFG_00902 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
HMFPNEFG_00903 7.5e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMFPNEFG_00904 7.3e-239 sufD O FeS assembly protein SufD
HMFPNEFG_00905 6.5e-145 sufC O FeS assembly ATPase SufC
HMFPNEFG_00906 4.2e-32 feoA P FeoA domain
HMFPNEFG_00907 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HMFPNEFG_00908 2.2e-268 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HMFPNEFG_00909 5.8e-157 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HMFPNEFG_00910 3.5e-64 ydiI Q Thioesterase superfamily
HMFPNEFG_00911 5.4e-109 yvrI K sigma factor activity
HMFPNEFG_00912 5e-202 G Transporter, major facilitator family protein
HMFPNEFG_00913 0.0 S Bacterial membrane protein YfhO
HMFPNEFG_00914 4.7e-102 T Ion transport 2 domain protein
HMFPNEFG_00915 5.7e-77 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMFPNEFG_00916 5.5e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMFPNEFG_00917 1.2e-95 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HMFPNEFG_00918 1.2e-194 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMFPNEFG_00919 5.8e-177 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HMFPNEFG_00921 0.0 L PLD-like domain
HMFPNEFG_00922 1.1e-95 mrr L restriction endonuclease
HMFPNEFG_00923 5.8e-166 L restriction endonuclease
HMFPNEFG_00924 7.4e-14 3.1.21.3 V Type I restriction modification DNA specificity domain
HMFPNEFG_00925 5.4e-56 3.1.21.3 V Type I restriction modification DNA specificity domain
HMFPNEFG_00926 8.9e-178 L Belongs to the 'phage' integrase family
HMFPNEFG_00927 4.2e-55 hsdS 3.1.21.3 V type I restriction modification DNA specificity domain
HMFPNEFG_00928 7.6e-281 hsdM 2.1.1.72 V type I restriction-modification system
HMFPNEFG_00929 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HMFPNEFG_00930 6.2e-140 IQ reductase
HMFPNEFG_00931 3.1e-57 yhaI S Protein of unknown function (DUF805)
HMFPNEFG_00932 2.2e-44
HMFPNEFG_00933 2.4e-22
HMFPNEFG_00934 3.5e-46
HMFPNEFG_00935 3.7e-96 K Acetyltransferase (GNAT) domain
HMFPNEFG_00936 2.9e-295 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMFPNEFG_00937 7.9e-228 gntT EG Gluconate
HMFPNEFG_00938 1.9e-181 K Transcriptional regulator, LacI family
HMFPNEFG_00939 7e-289 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMFPNEFG_00940 3.2e-95
HMFPNEFG_00941 2.1e-25
HMFPNEFG_00942 1.3e-61 asp S Asp23 family, cell envelope-related function
HMFPNEFG_00943 4.1e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HMFPNEFG_00945 2.7e-49
HMFPNEFG_00946 1.6e-67 yqkB S Belongs to the HesB IscA family
HMFPNEFG_00947 6.6e-173 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMFPNEFG_00948 1.7e-84 F NUDIX domain
HMFPNEFG_00949 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMFPNEFG_00950 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMFPNEFG_00951 5.5e-107 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMFPNEFG_00952 4.3e-166 lacX 5.1.3.3 G Aldose 1-epimerase
HMFPNEFG_00953 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMFPNEFG_00954 2.4e-161 dprA LU DNA protecting protein DprA
HMFPNEFG_00955 1.2e-140 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMFPNEFG_00956 4.6e-160 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMFPNEFG_00957 4.4e-35 yozE S Belongs to the UPF0346 family
HMFPNEFG_00958 1.6e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HMFPNEFG_00959 9.5e-172 ypmR E lipolytic protein G-D-S-L family
HMFPNEFG_00960 1.7e-151 DegV S EDD domain protein, DegV family
HMFPNEFG_00961 5.3e-113 hlyIII S protein, hemolysin III
HMFPNEFG_00962 1.9e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMFPNEFG_00963 5.9e-193 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMFPNEFG_00964 0.0 yfmR S ABC transporter, ATP-binding protein
HMFPNEFG_00965 9.6e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMFPNEFG_00966 1.5e-236 S Tetratricopeptide repeat protein
HMFPNEFG_00967 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMFPNEFG_00968 7.2e-250 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMFPNEFG_00969 2.5e-204 rpsA 1.17.7.4 J Ribosomal protein S1
HMFPNEFG_00970 3.4e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMFPNEFG_00971 8.5e-14 M Lysin motif
HMFPNEFG_00972 1.5e-269 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMFPNEFG_00973 9.1e-192 ypbB 5.1.3.1 S Helix-turn-helix domain
HMFPNEFG_00974 1.5e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMFPNEFG_00975 3.8e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMFPNEFG_00976 7.7e-106 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMFPNEFG_00977 7.6e-138 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMFPNEFG_00978 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMFPNEFG_00979 1.2e-163 xerD D recombinase XerD
HMFPNEFG_00980 2.3e-167 cvfB S S1 domain
HMFPNEFG_00981 2.1e-271 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMFPNEFG_00982 0.0 dnaE 2.7.7.7 L DNA polymerase
HMFPNEFG_00983 3.1e-30 S Protein of unknown function (DUF2929)
HMFPNEFG_00984 7.3e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMFPNEFG_00985 3.1e-158 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMFPNEFG_00986 9.6e-124 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMFPNEFG_00987 1.2e-219 patA 2.6.1.1 E Aminotransferase
HMFPNEFG_00988 3.8e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMFPNEFG_00989 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMFPNEFG_00990 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMFPNEFG_00991 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMFPNEFG_00992 6.8e-147 recO L Involved in DNA repair and RecF pathway recombination
HMFPNEFG_00993 1.9e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMFPNEFG_00994 1.5e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HMFPNEFG_00995 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMFPNEFG_00996 1.2e-183 phoH T phosphate starvation-inducible protein PhoH
HMFPNEFG_00997 1.7e-176 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMFPNEFG_00998 1.1e-90 bioY S BioY family
HMFPNEFG_00999 8.3e-265 argH 4.3.2.1 E argininosuccinate lyase
HMFPNEFG_01000 3.2e-155 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMFPNEFG_01001 2.7e-39 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HMFPNEFG_01002 1.5e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMFPNEFG_01003 9.6e-73 L PFAM Integrase catalytic region
HMFPNEFG_01004 3.8e-70 yqeY S YqeY-like protein
HMFPNEFG_01005 7.5e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMFPNEFG_01006 2.4e-265 glnPH2 P ABC transporter permease
HMFPNEFG_01007 6.5e-131 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMFPNEFG_01008 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMFPNEFG_01009 1e-164 yniA G Phosphotransferase enzyme family
HMFPNEFG_01010 8.4e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMFPNEFG_01011 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMFPNEFG_01012 1.2e-52
HMFPNEFG_01013 4.6e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HMFPNEFG_01014 1.1e-178 prmA J Ribosomal protein L11 methyltransferase
HMFPNEFG_01015 2.8e-57
HMFPNEFG_01017 8e-174 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMFPNEFG_01019 4e-198 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HMFPNEFG_01020 4.1e-275 pipD E Dipeptidase
HMFPNEFG_01021 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMFPNEFG_01022 5.1e-199 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMFPNEFG_01023 0.0 dnaK O Heat shock 70 kDa protein
HMFPNEFG_01024 2.3e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMFPNEFG_01025 4.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMFPNEFG_01026 5.8e-64
HMFPNEFG_01027 7.6e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMFPNEFG_01028 6.2e-168 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMFPNEFG_01029 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMFPNEFG_01030 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMFPNEFG_01031 4.5e-49 ylxQ J ribosomal protein
HMFPNEFG_01032 1e-44 ylxR K Protein of unknown function (DUF448)
HMFPNEFG_01033 1e-215 nusA K Participates in both transcription termination and antitermination
HMFPNEFG_01034 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HMFPNEFG_01035 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMFPNEFG_01036 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMFPNEFG_01037 9.2e-234 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMFPNEFG_01038 1.3e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HMFPNEFG_01039 9.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMFPNEFG_01040 2.2e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMFPNEFG_01041 2e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMFPNEFG_01042 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMFPNEFG_01043 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
HMFPNEFG_01044 2.8e-182 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMFPNEFG_01045 5.4e-49 yazA L GIY-YIG catalytic domain protein
HMFPNEFG_01046 6.4e-142 yabB 2.1.1.223 L Methyltransferase small domain
HMFPNEFG_01047 4.6e-117 plsC 2.3.1.51 I Acyltransferase
HMFPNEFG_01048 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
HMFPNEFG_01049 1.3e-35 ynzC S UPF0291 protein
HMFPNEFG_01050 4.7e-114 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMFPNEFG_01051 2.6e-211 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMFPNEFG_01052 1.8e-124 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMFPNEFG_01054 2.1e-87
HMFPNEFG_01055 2.7e-91 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMFPNEFG_01056 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMFPNEFG_01057 6.5e-156 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMFPNEFG_01058 1.3e-176 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMFPNEFG_01059 4e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMFPNEFG_01060 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMFPNEFG_01061 1.3e-08
HMFPNEFG_01062 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HMFPNEFG_01063 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
HMFPNEFG_01064 1.4e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMFPNEFG_01065 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMFPNEFG_01066 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMFPNEFG_01067 3.5e-163 S Tetratricopeptide repeat
HMFPNEFG_01068 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMFPNEFG_01069 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMFPNEFG_01070 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
HMFPNEFG_01071 1.2e-146 holA 2.7.7.7 L DNA polymerase III delta subunit
HMFPNEFG_01072 0.0 comEC S Competence protein ComEC
HMFPNEFG_01073 6.9e-89 comEB 3.5.4.12 F ComE operon protein 2
HMFPNEFG_01074 2.6e-80 comEA L Competence protein ComEA
HMFPNEFG_01075 4.3e-197 ylbL T Belongs to the peptidase S16 family
HMFPNEFG_01076 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMFPNEFG_01077 6.5e-99 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMFPNEFG_01078 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMFPNEFG_01079 2e-222 ftsW D Belongs to the SEDS family
HMFPNEFG_01080 0.0 typA T GTP-binding protein TypA
HMFPNEFG_01081 2.8e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HMFPNEFG_01082 1.4e-47 yktA S Belongs to the UPF0223 family
HMFPNEFG_01083 4.1e-275 lpdA 1.8.1.4 C Dehydrogenase
HMFPNEFG_01084 1.8e-224 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HMFPNEFG_01085 2.4e-181 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HMFPNEFG_01086 3e-209 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HMFPNEFG_01087 8.2e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMFPNEFG_01088 1.6e-77
HMFPNEFG_01089 9.8e-32 ykzG S Belongs to the UPF0356 family
HMFPNEFG_01090 5.7e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HMFPNEFG_01091 5.7e-29
HMFPNEFG_01092 1.2e-133 mltD CBM50 M NlpC P60 family protein
HMFPNEFG_01094 7.7e-58
HMFPNEFG_01095 2.3e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMFPNEFG_01096 1.7e-219 EG GntP family permease
HMFPNEFG_01097 8.5e-84 KT Putative sugar diacid recognition
HMFPNEFG_01098 3.9e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMFPNEFG_01099 5.5e-217 patA 2.6.1.1 E Aminotransferase
HMFPNEFG_01100 5.8e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMFPNEFG_01101 1.3e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMFPNEFG_01102 1.9e-222 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMFPNEFG_01103 1.2e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMFPNEFG_01104 2.3e-248 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMFPNEFG_01105 5.1e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMFPNEFG_01106 2.1e-169 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMFPNEFG_01107 9e-23 UW LPXTG-motif cell wall anchor domain protein
HMFPNEFG_01108 4e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMFPNEFG_01109 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMFPNEFG_01110 9e-119 S Repeat protein
HMFPNEFG_01111 1.1e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HMFPNEFG_01112 1.8e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMFPNEFG_01113 3.7e-57 XK27_04120 S Putative amino acid metabolism
HMFPNEFG_01114 1.1e-214 iscS 2.8.1.7 E Aminotransferase class V
HMFPNEFG_01115 1e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMFPNEFG_01117 1.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMFPNEFG_01118 4.2e-32 cspA K Cold shock protein
HMFPNEFG_01119 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMFPNEFG_01120 1.9e-42 divIVA D DivIVA domain protein
HMFPNEFG_01121 5.1e-142 ylmH S S4 domain protein
HMFPNEFG_01122 3.2e-40 yggT S YGGT family
HMFPNEFG_01123 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMFPNEFG_01124 5.3e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMFPNEFG_01125 6.6e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMFPNEFG_01126 8.7e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMFPNEFG_01127 3e-204 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMFPNEFG_01128 8.5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMFPNEFG_01129 3.4e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMFPNEFG_01130 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMFPNEFG_01131 2.6e-56 ftsL D Cell division protein FtsL
HMFPNEFG_01132 1.2e-174 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMFPNEFG_01133 3.1e-77 mraZ K Belongs to the MraZ family
HMFPNEFG_01134 7.3e-56
HMFPNEFG_01135 1.2e-10 S Protein of unknown function (DUF4044)
HMFPNEFG_01136 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMFPNEFG_01137 3.9e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMFPNEFG_01138 3.7e-162 rrmA 2.1.1.187 H Methyltransferase
HMFPNEFG_01139 2.3e-182 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMFPNEFG_01142 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HMFPNEFG_01143 3e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMFPNEFG_01144 2e-115 yjbM 2.7.6.5 S RelA SpoT domain protein
HMFPNEFG_01145 4.7e-114 yjbH Q Thioredoxin
HMFPNEFG_01146 9.2e-264 pipD E Dipeptidase
HMFPNEFG_01147 1.3e-125 coiA 3.6.4.12 S Competence protein
HMFPNEFG_01148 3.2e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMFPNEFG_01149 1.6e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMFPNEFG_01150 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HMFPNEFG_01174 5.5e-110 dedA S SNARE-like domain protein
HMFPNEFG_01175 2.4e-105 S Protein of unknown function (DUF1461)
HMFPNEFG_01176 1.1e-133 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMFPNEFG_01177 1.3e-93 yutD S Protein of unknown function (DUF1027)
HMFPNEFG_01178 1.2e-111 S Calcineurin-like phosphoesterase
HMFPNEFG_01179 2.1e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMFPNEFG_01180 1.7e-145 ytxK 2.1.1.72 L N-6 DNA Methylase
HMFPNEFG_01182 6.3e-70
HMFPNEFG_01183 2.7e-40
HMFPNEFG_01184 8.3e-78 NU general secretion pathway protein
HMFPNEFG_01185 7.1e-47 comGC U competence protein ComGC
HMFPNEFG_01186 9.5e-181 comGB NU type II secretion system
HMFPNEFG_01187 2.6e-180 comGA NU Type II IV secretion system protein
HMFPNEFG_01188 3.5e-132 yebC K Transcriptional regulatory protein
HMFPNEFG_01189 1.9e-134
HMFPNEFG_01190 2.9e-182 ccpA K catabolite control protein A
HMFPNEFG_01191 4.2e-211 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMFPNEFG_01192 3.5e-26
HMFPNEFG_01193 9.4e-37 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMFPNEFG_01194 3.4e-147 ykuT M mechanosensitive ion channel
HMFPNEFG_01195 2e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
HMFPNEFG_01196 3.6e-76 ykuL S (CBS) domain
HMFPNEFG_01197 4.4e-94 S Phosphoesterase
HMFPNEFG_01198 2.7e-103 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMFPNEFG_01199 2.1e-143 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMFPNEFG_01200 1.3e-96 yslB S Protein of unknown function (DUF2507)
HMFPNEFG_01201 6.1e-54 trxA O Belongs to the thioredoxin family
HMFPNEFG_01202 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMFPNEFG_01203 1e-85 cvpA S Colicin V production protein
HMFPNEFG_01204 6.1e-48 yrzB S Belongs to the UPF0473 family
HMFPNEFG_01205 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMFPNEFG_01206 4.1e-43 yrzL S Belongs to the UPF0297 family
HMFPNEFG_01207 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMFPNEFG_01208 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMFPNEFG_01209 4.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMFPNEFG_01210 2.8e-31 yajC U Preprotein translocase
HMFPNEFG_01211 2.6e-189 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HMFPNEFG_01212 3.4e-191 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMFPNEFG_01213 1.9e-101 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMFPNEFG_01214 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMFPNEFG_01215 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMFPNEFG_01216 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
HMFPNEFG_01217 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMFPNEFG_01218 1.9e-228 cinA 3.5.1.42 S Belongs to the CinA family
HMFPNEFG_01219 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMFPNEFG_01220 7.4e-141 ymfM S Helix-turn-helix domain
HMFPNEFG_01221 3.2e-250 ymfH S Peptidase M16
HMFPNEFG_01222 1.6e-230 ymfF S Peptidase M16 inactive domain protein
HMFPNEFG_01223 2.6e-160 aatB ET ABC transporter substrate-binding protein
HMFPNEFG_01224 2.1e-117 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMFPNEFG_01225 3.2e-102 glnP P ABC transporter permease
HMFPNEFG_01226 1.2e-91 mreD M rod shape-determining protein MreD
HMFPNEFG_01227 2.2e-151 mreC M Involved in formation and maintenance of cell shape
HMFPNEFG_01228 1.7e-179 mreB D cell shape determining protein MreB
HMFPNEFG_01229 6.8e-121 radC L DNA repair protein
HMFPNEFG_01230 1.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMFPNEFG_01231 7.6e-230 ndh 1.6.99.3 C NADH dehydrogenase
HMFPNEFG_01232 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMFPNEFG_01233 2.8e-310 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMFPNEFG_01234 6.3e-185 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMFPNEFG_01235 1.9e-272 cydA 1.10.3.14 C ubiquinol oxidase
HMFPNEFG_01236 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMFPNEFG_01237 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMFPNEFG_01238 1.3e-215 iscS2 2.8.1.7 E Aminotransferase class V
HMFPNEFG_01239 2.2e-230 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMFPNEFG_01240 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMFPNEFG_01241 3.8e-198 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMFPNEFG_01242 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMFPNEFG_01243 2.5e-135 S Belongs to the UPF0246 family
HMFPNEFG_01244 2.5e-138 S Membrane
HMFPNEFG_01245 1.4e-74 4.4.1.5 E Glyoxalase
HMFPNEFG_01246 7.1e-86 yueI S Protein of unknown function (DUF1694)
HMFPNEFG_01247 1.7e-235 rarA L recombination factor protein RarA
HMFPNEFG_01248 4.4e-46
HMFPNEFG_01249 4.3e-83 usp6 T universal stress protein
HMFPNEFG_01250 2.4e-206 araR K Transcriptional regulator
HMFPNEFG_01251 7.1e-158 ytbE 1.1.1.346 S Aldo keto reductase
HMFPNEFG_01252 1.1e-93 maa 2.3.1.79 S Maltose O-acetyltransferase
HMFPNEFG_01253 4.4e-285 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HMFPNEFG_01254 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMFPNEFG_01255 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
HMFPNEFG_01256 2.6e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HMFPNEFG_01257 7.2e-96 L Helix-turn-helix domain
HMFPNEFG_01258 9.6e-139 L hmm pf00665
HMFPNEFG_01259 1.9e-147 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HMFPNEFG_01260 5.3e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMFPNEFG_01261 3.3e-46 gcvH E glycine cleavage
HMFPNEFG_01262 4.1e-220 rodA D Belongs to the SEDS family
HMFPNEFG_01263 1e-31 S Protein of unknown function (DUF2969)
HMFPNEFG_01264 1.9e-178 mbl D Cell shape determining protein MreB Mrl
HMFPNEFG_01265 6.1e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMFPNEFG_01266 1.3e-33 ywzB S Protein of unknown function (DUF1146)
HMFPNEFG_01267 1.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMFPNEFG_01268 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMFPNEFG_01269 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMFPNEFG_01270 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMFPNEFG_01271 6.7e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMFPNEFG_01272 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMFPNEFG_01273 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMFPNEFG_01274 7.3e-124 atpB C it plays a direct role in the translocation of protons across the membrane
HMFPNEFG_01275 5e-232 pyrP F Permease
HMFPNEFG_01276 6.3e-129 yibF S overlaps another CDS with the same product name
HMFPNEFG_01277 9.9e-192 yibE S overlaps another CDS with the same product name
HMFPNEFG_01278 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMFPNEFG_01279 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMFPNEFG_01280 9.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMFPNEFG_01281 1e-195 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMFPNEFG_01282 5.7e-163 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMFPNEFG_01283 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMFPNEFG_01284 6e-108 tdk 2.7.1.21 F thymidine kinase
HMFPNEFG_01285 4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HMFPNEFG_01286 3.2e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HMFPNEFG_01287 2.7e-223 arcD U Amino acid permease
HMFPNEFG_01288 2e-261 E Arginine ornithine antiporter
HMFPNEFG_01289 4.7e-79 argR K Regulates arginine biosynthesis genes
HMFPNEFG_01290 1.2e-238 arcA 3.5.3.6 E Arginine
HMFPNEFG_01291 8.8e-187 ampC V Beta-lactamase
HMFPNEFG_01292 1.9e-32
HMFPNEFG_01293 0.0 M domain protein
HMFPNEFG_01294 5.9e-91
HMFPNEFG_01295 2e-158 L Transposase
HMFPNEFG_01296 4.8e-09 S Domain of unknown function (DUF4767)
HMFPNEFG_01297 4e-234 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMFPNEFG_01298 2.5e-129 narI 1.7.5.1 C Nitrate reductase
HMFPNEFG_01299 2.7e-100 narJ C nitrate reductase molybdenum cofactor assembly chaperone
HMFPNEFG_01300 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
HMFPNEFG_01301 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMFPNEFG_01302 5.7e-186 moeB 2.7.7.73, 2.7.7.80 H ThiF family
HMFPNEFG_01303 3.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HMFPNEFG_01304 8.5e-229 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
HMFPNEFG_01305 5.1e-84 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HMFPNEFG_01306 4.7e-105 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HMFPNEFG_01307 3e-44
HMFPNEFG_01308 1e-190 comP 2.7.13.3 F Sensor histidine kinase
HMFPNEFG_01309 2.3e-116 nreC K PFAM regulatory protein LuxR
HMFPNEFG_01310 1.6e-18
HMFPNEFG_01311 3.6e-182
HMFPNEFG_01312 8.4e-165 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
HMFPNEFG_01314 1.9e-159 yjcE P Sodium proton antiporter
HMFPNEFG_01315 1.6e-74 yjcE P Sodium proton antiporter
HMFPNEFG_01317 5.2e-56
HMFPNEFG_01319 1.7e-84
HMFPNEFG_01320 0.0 copA 3.6.3.54 P P-type ATPase
HMFPNEFG_01321 6.3e-50 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMFPNEFG_01322 1.3e-55 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMFPNEFG_01323 4.5e-103 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMFPNEFG_01324 1.2e-160 EG EamA-like transporter family
HMFPNEFG_01325 4.3e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HMFPNEFG_01326 3.4e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMFPNEFG_01327 8.1e-154 KT YcbB domain
HMFPNEFG_01328 2.7e-301 xylB 2.7.1.17 G Belongs to the FGGY kinase family
HMFPNEFG_01329 7.6e-271 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HMFPNEFG_01330 2.4e-12 pgdA 3.5.1.104 G polysaccharide deacetylase
HMFPNEFG_01331 2.7e-59 O Bacterial dnaA protein
HMFPNEFG_01332 0.0 3.2.1.55 GH51 G Right handed beta helix region
HMFPNEFG_01333 1.6e-290 xynT G MFS/sugar transport protein
HMFPNEFG_01334 8.6e-173 rhaS2 K Transcriptional regulator, AraC family
HMFPNEFG_01335 4.3e-261 xylT EGP Major facilitator Superfamily
HMFPNEFG_01337 1.6e-216 xylR GK ROK family
HMFPNEFG_01338 1.3e-28
HMFPNEFG_01339 1e-262 pgi 5.3.1.9 G Belongs to the GPI family
HMFPNEFG_01340 9e-94 lacA 2.3.1.79 S Transferase hexapeptide repeat
HMFPNEFG_01341 2.6e-155 glcU U sugar transport
HMFPNEFG_01342 2e-272 yclK 2.7.13.3 T Histidine kinase
HMFPNEFG_01343 1.5e-132 K response regulator
HMFPNEFG_01345 2.8e-79 lytE M Lysin motif
HMFPNEFG_01346 2e-149 XK27_02985 S Cof-like hydrolase
HMFPNEFG_01347 2.3e-81 K Transcriptional regulator
HMFPNEFG_01348 0.0 oatA I Acyltransferase
HMFPNEFG_01349 1.5e-52
HMFPNEFG_01350 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMFPNEFG_01351 9.4e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMFPNEFG_01352 2e-126 ybbR S YbbR-like protein
HMFPNEFG_01353 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMFPNEFG_01354 4.8e-249 fucP G Major Facilitator Superfamily
HMFPNEFG_01355 1.7e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HMFPNEFG_01356 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMFPNEFG_01357 3.6e-168 murB 1.3.1.98 M Cell wall formation
HMFPNEFG_01358 3.9e-101 dnaQ 2.7.7.7 L DNA polymerase III
HMFPNEFG_01359 4.4e-76 S PAS domain
HMFPNEFG_01360 2.6e-86 K Acetyltransferase (GNAT) domain
HMFPNEFG_01361 2.9e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMFPNEFG_01362 3.8e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMFPNEFG_01363 6.2e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMFPNEFG_01364 6.3e-105 yxjI
HMFPNEFG_01365 1.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMFPNEFG_01366 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMFPNEFG_01367 7.5e-146 est 3.1.1.1 S Serine aminopeptidase, S33
HMFPNEFG_01368 1.8e-34 secG U Preprotein translocase
HMFPNEFG_01369 4e-292 clcA P chloride
HMFPNEFG_01370 7.1e-248 yifK E Amino acid permease
HMFPNEFG_01371 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMFPNEFG_01372 4.8e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMFPNEFG_01373 3.2e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMFPNEFG_01374 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMFPNEFG_01376 2.7e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMFPNEFG_01377 8.8e-15
HMFPNEFG_01379 4e-170 whiA K May be required for sporulation
HMFPNEFG_01380 1.4e-186 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMFPNEFG_01381 1.1e-161 rapZ S Displays ATPase and GTPase activities
HMFPNEFG_01382 5.4e-245 steT E amino acid
HMFPNEFG_01383 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMFPNEFG_01384 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMFPNEFG_01385 1.5e-13
HMFPNEFG_01386 2.3e-116 yfbR S HD containing hydrolase-like enzyme
HMFPNEFG_01387 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMFPNEFG_01388 7.9e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HMFPNEFG_01389 1.3e-102 aatB ET PFAM extracellular solute-binding protein, family 3
HMFPNEFG_01390 5.9e-32 aatB ET PFAM extracellular solute-binding protein, family 3
HMFPNEFG_01391 3.8e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMFPNEFG_01392 5e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMFPNEFG_01393 3.5e-163 lutA C Cysteine-rich domain
HMFPNEFG_01394 7.5e-288 lutB C 4Fe-4S dicluster domain
HMFPNEFG_01395 3.9e-136 yrjD S LUD domain
HMFPNEFG_01396 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMFPNEFG_01397 1.8e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMFPNEFG_01398 2.2e-156 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMFPNEFG_01399 3.3e-175 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMFPNEFG_01400 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HMFPNEFG_01401 3.1e-32 KT PspC domain protein
HMFPNEFG_01402 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMFPNEFG_01403 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMFPNEFG_01404 1.5e-95 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMFPNEFG_01405 1.3e-114 comFC S Competence protein
HMFPNEFG_01406 1.4e-256 comFA L Helicase C-terminal domain protein
HMFPNEFG_01407 2.9e-111 yvyE 3.4.13.9 S YigZ family
HMFPNEFG_01408 1.1e-227 EGP Major facilitator Superfamily
HMFPNEFG_01409 7.4e-68 rmaI K Transcriptional regulator
HMFPNEFG_01410 1.2e-39
HMFPNEFG_01411 0.0 ydaO E amino acid
HMFPNEFG_01412 4.3e-305 ybeC E amino acid
HMFPNEFG_01413 8.2e-82 S YbaK proline--tRNA ligase associated domain protein
HMFPNEFG_01414 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMFPNEFG_01415 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMFPNEFG_01417 1.4e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMFPNEFG_01418 0.0 uup S ABC transporter, ATP-binding protein
HMFPNEFG_01419 1.8e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HMFPNEFG_01420 2.6e-191 mtnE 2.6.1.83 E Aminotransferase
HMFPNEFG_01421 2.3e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HMFPNEFG_01422 1.4e-136 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMFPNEFG_01423 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMFPNEFG_01424 3.6e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMFPNEFG_01425 8.6e-198 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMFPNEFG_01426 1.5e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMFPNEFG_01427 2.8e-126 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMFPNEFG_01428 5.9e-114 L PFAM Integrase catalytic region
HMFPNEFG_01429 4.4e-57 L PFAM Integrase catalytic region
HMFPNEFG_01430 4.2e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMFPNEFG_01431 5.3e-173 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMFPNEFG_01432 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HMFPNEFG_01433 8.5e-279 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMFPNEFG_01434 1.5e-135 fat 3.1.2.21 I Acyl-ACP thioesterase
HMFPNEFG_01435 2e-155 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMFPNEFG_01436 5.9e-58 yabA L Involved in initiation control of chromosome replication
HMFPNEFG_01437 2.8e-185 holB 2.7.7.7 L DNA polymerase III
HMFPNEFG_01438 7.6e-52 yaaQ S Cyclic-di-AMP receptor
HMFPNEFG_01439 4.8e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMFPNEFG_01440 9.7e-39 S Protein of unknown function (DUF2508)
HMFPNEFG_01441 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMFPNEFG_01442 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMFPNEFG_01443 4.7e-300 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMFPNEFG_01444 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMFPNEFG_01445 3.4e-35 nrdH O Glutaredoxin
HMFPNEFG_01446 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMFPNEFG_01447 3.4e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMFPNEFG_01448 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMFPNEFG_01449 6.4e-126 S Putative adhesin
HMFPNEFG_01450 1.6e-82 XK27_06920 S Protein of unknown function (DUF1700)
HMFPNEFG_01451 4e-56 K transcriptional regulator PadR family
HMFPNEFG_01452 2e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMFPNEFG_01454 1.5e-48
HMFPNEFG_01455 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMFPNEFG_01456 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMFPNEFG_01457 1.3e-207 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMFPNEFG_01458 6.2e-246 M Glycosyl transferase family group 2
HMFPNEFG_01460 1.3e-226 aadAT EK Aminotransferase, class I
HMFPNEFG_01461 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMFPNEFG_01462 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMFPNEFG_01463 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
HMFPNEFG_01464 2.2e-16 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMFPNEFG_01465 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMFPNEFG_01466 2.3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMFPNEFG_01467 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMFPNEFG_01468 1.7e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMFPNEFG_01469 1.7e-207 yacL S domain protein
HMFPNEFG_01470 2.3e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMFPNEFG_01471 2e-97 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMFPNEFG_01472 1.5e-49 HA62_12640 S GCN5-related N-acetyl-transferase
HMFPNEFG_01473 2.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMFPNEFG_01474 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HMFPNEFG_01475 7.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HMFPNEFG_01476 6.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMFPNEFG_01477 2.4e-119 tcyB E ABC transporter
HMFPNEFG_01478 9.4e-214 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HMFPNEFG_01479 3.1e-169 I alpha/beta hydrolase fold
HMFPNEFG_01480 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMFPNEFG_01481 0.0 S Bacterial membrane protein, YfhO
HMFPNEFG_01482 1.3e-184 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMFPNEFG_01483 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMFPNEFG_01485 4.3e-85 ydcK S Belongs to the SprT family
HMFPNEFG_01486 0.0 yhgF K Tex-like protein N-terminal domain protein
HMFPNEFG_01487 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMFPNEFG_01488 1.3e-284 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMFPNEFG_01489 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
HMFPNEFG_01490 1.4e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMFPNEFG_01491 6.2e-299 aspT P Predicted Permease Membrane Region
HMFPNEFG_01492 2.8e-252 EGP Major facilitator Superfamily
HMFPNEFG_01493 2.7e-109
HMFPNEFG_01496 1.4e-158 yjjH S Calcineurin-like phosphoesterase
HMFPNEFG_01497 5e-263 dtpT U amino acid peptide transporter
HMFPNEFG_01498 3.7e-19
HMFPNEFG_01500 3.7e-91 yqiG C Oxidoreductase
HMFPNEFG_01501 7.8e-20 yqiG C Oxidoreductase
HMFPNEFG_01502 1.1e-50 yqiG C Oxidoreductase
HMFPNEFG_01503 8.5e-54 S macrophage migration inhibitory factor
HMFPNEFG_01504 2.4e-65 K HxlR-like helix-turn-helix
HMFPNEFG_01505 2.1e-88 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMFPNEFG_01507 1.9e-225 L Transposase IS66 family
HMFPNEFG_01508 3.5e-14 D nuclear chromosome segregation
HMFPNEFG_01509 2e-108 S Peptidase, M23
HMFPNEFG_01510 1.7e-59 M Peptidase_C39 like family
HMFPNEFG_01511 1.4e-118 ganB 3.2.1.89 G arabinogalactan
HMFPNEFG_01512 8.7e-143 ganB 3.2.1.89 G arabinogalactan
HMFPNEFG_01513 5.5e-280 O Arylsulfotransferase (ASST)
HMFPNEFG_01514 3.6e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMFPNEFG_01515 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMFPNEFG_01516 1.4e-170 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMFPNEFG_01517 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMFPNEFG_01518 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMFPNEFG_01519 3.8e-257 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMFPNEFG_01520 9.8e-67 yabR J RNA binding
HMFPNEFG_01521 3.3e-56 divIC D Septum formation initiator
HMFPNEFG_01522 8.1e-39 yabO J S4 domain protein
HMFPNEFG_01523 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMFPNEFG_01524 3.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMFPNEFG_01525 4e-113 S (CBS) domain
HMFPNEFG_01526 3.1e-147 tesE Q hydratase
HMFPNEFG_01527 4.7e-243 codA 3.5.4.1 F cytosine deaminase
HMFPNEFG_01528 6.8e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HMFPNEFG_01529 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
HMFPNEFG_01530 1.9e-211 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMFPNEFG_01531 2.2e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMFPNEFG_01533 6.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMFPNEFG_01534 2.8e-232 dltB M MBOAT, membrane-bound O-acyltransferase family
HMFPNEFG_01535 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMFPNEFG_01536 1.4e-253 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMFPNEFG_01537 1.3e-165 glsA 3.5.1.2 E Belongs to the glutaminase family
HMFPNEFG_01538 1e-141 sprD D Domain of Unknown Function (DUF1542)
HMFPNEFG_01539 2.1e-127 L PFAM Integrase catalytic region
HMFPNEFG_01540 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMFPNEFG_01541 1.8e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMFPNEFG_01542 7.5e-158 htpX O Belongs to the peptidase M48B family
HMFPNEFG_01543 7e-93 lemA S LemA family
HMFPNEFG_01544 5.7e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMFPNEFG_01545 4.6e-120 pgm3 G Belongs to the phosphoglycerate mutase family
HMFPNEFG_01546 1.4e-161 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMFPNEFG_01547 3.1e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMFPNEFG_01548 1.1e-234 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMFPNEFG_01549 5.1e-125 srtA 3.4.22.70 M sortase family
HMFPNEFG_01550 1.3e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HMFPNEFG_01551 1.2e-236 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMFPNEFG_01552 4.6e-41 rpmE2 J Ribosomal protein L31
HMFPNEFG_01553 5.7e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMFPNEFG_01554 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMFPNEFG_01555 8.7e-51 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMFPNEFG_01556 3e-66 ywiB S Domain of unknown function (DUF1934)
HMFPNEFG_01557 7.9e-146 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HMFPNEFG_01558 5e-270 ywfO S HD domain protein
HMFPNEFG_01559 2.5e-147 yxeH S hydrolase
HMFPNEFG_01560 2.1e-49
HMFPNEFG_01561 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMFPNEFG_01562 7.5e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMFPNEFG_01563 2.6e-149 purR 2.4.2.7 F pur operon repressor
HMFPNEFG_01564 1.4e-118 znuB U ABC 3 transport family
HMFPNEFG_01565 2.2e-122 fhuC P ABC transporter
HMFPNEFG_01566 8.2e-168 znuA P Belongs to the bacterial solute-binding protein 9 family
HMFPNEFG_01567 4.9e-159 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMFPNEFG_01568 6.8e-37 veg S Biofilm formation stimulator VEG
HMFPNEFG_01569 5.2e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMFPNEFG_01570 3.2e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMFPNEFG_01571 3.8e-156 tatD L hydrolase, TatD family
HMFPNEFG_01572 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMFPNEFG_01573 3.6e-162 yunF F Protein of unknown function DUF72
HMFPNEFG_01575 3e-130 cobB K SIR2 family
HMFPNEFG_01576 1.6e-177
HMFPNEFG_01577 2.1e-222 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HMFPNEFG_01578 1.3e-165 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HMFPNEFG_01579 9.1e-192 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMFPNEFG_01580 1.7e-187 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMFPNEFG_01581 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
HMFPNEFG_01582 0.0 helD 3.6.4.12 L DNA helicase
HMFPNEFG_01583 5.3e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMFPNEFG_01585 1.3e-254 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HMFPNEFG_01586 1e-265 yfnA E amino acid
HMFPNEFG_01587 9.3e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMFPNEFG_01588 9.3e-31 1.3.5.4 S FMN binding
HMFPNEFG_01589 1.6e-219 norA EGP Major facilitator Superfamily
HMFPNEFG_01590 1.1e-136 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HMFPNEFG_01591 2.8e-154 metQ1 P Belongs to the nlpA lipoprotein family
HMFPNEFG_01592 4.7e-191 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMFPNEFG_01593 3.1e-103 metI P ABC transporter permease
HMFPNEFG_01594 2.2e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMFPNEFG_01595 1.2e-252 clcA P chloride
HMFPNEFG_01596 6.9e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMFPNEFG_01597 4.5e-104 proW P ABC transporter, permease protein
HMFPNEFG_01598 5.1e-139 proV E ABC transporter, ATP-binding protein
HMFPNEFG_01599 6.3e-109 proWZ P ABC transporter permease
HMFPNEFG_01600 2.3e-162 proX M ABC transporter, substrate-binding protein, QAT family
HMFPNEFG_01601 9e-75 K Transcriptional regulator
HMFPNEFG_01602 4.8e-154 1.6.5.2 GM NAD(P)H-binding
HMFPNEFG_01604 3.3e-217 5.4.2.7 G Metalloenzyme superfamily
HMFPNEFG_01605 0.0 cadA P P-type ATPase
HMFPNEFG_01606 2.1e-110 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMFPNEFG_01607 2.1e-126
HMFPNEFG_01608 3.3e-55 S Sugar efflux transporter for intercellular exchange
HMFPNEFG_01609 3.2e-253 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
HMFPNEFG_01611 0.0 L Helicase C-terminal domain protein
HMFPNEFG_01612 9.9e-75 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
HMFPNEFG_01613 2.6e-177 S Aldo keto reductase
HMFPNEFG_01615 5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMFPNEFG_01616 4.5e-62 psiE S Phosphate-starvation-inducible E
HMFPNEFG_01617 2.1e-102 ydeN S Serine hydrolase
HMFPNEFG_01619 3.4e-155 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HMFPNEFG_01620 4.7e-255 nhaC C Na H antiporter NhaC
HMFPNEFG_01621 2.7e-38 S Cytochrome b5-like Heme/Steroid binding domain
HMFPNEFG_01622 4.8e-114 ywnB S NAD(P)H-binding
HMFPNEFG_01623 2.9e-37
HMFPNEFG_01624 5.5e-130 IQ Dehydrogenase reductase
HMFPNEFG_01625 1.8e-240 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
HMFPNEFG_01627 1.3e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMFPNEFG_01628 1.5e-173
HMFPNEFG_01629 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMFPNEFG_01630 6.9e-242 purD 6.3.4.13 F Belongs to the GARS family
HMFPNEFG_01631 8.6e-295 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HMFPNEFG_01632 2.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMFPNEFG_01633 4.4e-194 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HMFPNEFG_01634 2.2e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HMFPNEFG_01635 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMFPNEFG_01636 2.3e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMFPNEFG_01637 7e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HMFPNEFG_01638 9.7e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HMFPNEFG_01639 2e-252 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMFPNEFG_01640 1.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMFPNEFG_01641 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMFPNEFG_01642 1.3e-131 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HMFPNEFG_01643 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HMFPNEFG_01644 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMFPNEFG_01645 4.9e-177 K AI-2E family transporter
HMFPNEFG_01646 1.1e-236 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMFPNEFG_01647 7.9e-96 ribA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HMFPNEFG_01648 5.1e-116 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
HMFPNEFG_01649 2.5e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMFPNEFG_01650 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMFPNEFG_01651 8.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMFPNEFG_01652 3.9e-248 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMFPNEFG_01653 9.5e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMFPNEFG_01654 7.4e-134 K LysR substrate binding domain
HMFPNEFG_01655 1.6e-52 azlD S branched-chain amino acid
HMFPNEFG_01656 3.7e-136 azlC E AzlC protein
HMFPNEFG_01657 6.5e-199 hpk31 2.7.13.3 T Histidine kinase
HMFPNEFG_01658 1.2e-123 K response regulator
HMFPNEFG_01659 2.9e-207 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMFPNEFG_01660 9.5e-172 deoR K sugar-binding domain protein
HMFPNEFG_01661 1.1e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HMFPNEFG_01662 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HMFPNEFG_01663 2.9e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HMFPNEFG_01664 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HMFPNEFG_01665 7.7e-135 XK27_01040 S Protein of unknown function (DUF1129)
HMFPNEFG_01666 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMFPNEFG_01667 5.4e-32 yyzM S Bacterial protein of unknown function (DUF951)
HMFPNEFG_01668 1.7e-154 spo0J K Belongs to the ParB family
HMFPNEFG_01669 3.9e-139 soj D Sporulation initiation inhibitor
HMFPNEFG_01670 4.3e-151 noc K Belongs to the ParB family
HMFPNEFG_01671 2.5e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMFPNEFG_01672 1.4e-161 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HMFPNEFG_01673 5.6e-169 rihC 3.2.2.1 F Nucleoside
HMFPNEFG_01674 2.3e-218 nupG F Nucleoside transporter
HMFPNEFG_01675 7.2e-221 cycA E Amino acid permease
HMFPNEFG_01677 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMFPNEFG_01678 1.2e-264 glnP P ABC transporter
HMFPNEFG_01679 3.8e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMFPNEFG_01680 3.1e-130 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMFPNEFG_01681 4e-28 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMFPNEFG_01682 1.6e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMFPNEFG_01683 6.1e-198 XK27_09615 S reductase
HMFPNEFG_01684 1.2e-100 nqr 1.5.1.36 S reductase
HMFPNEFG_01686 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMFPNEFG_01687 2.4e-181 K Transcriptional regulator, LacI family
HMFPNEFG_01688 8.3e-138 G Major Facilitator
HMFPNEFG_01689 7.4e-71 G Major Facilitator
HMFPNEFG_01690 8.1e-207 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMFPNEFG_01691 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMFPNEFG_01692 3.2e-264 G Major Facilitator
HMFPNEFG_01693 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HMFPNEFG_01694 7.1e-277 M domain protein
HMFPNEFG_01695 1.8e-260 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HMFPNEFG_01696 4.8e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HMFPNEFG_01697 2.2e-72
HMFPNEFG_01698 6.2e-76 K Transcriptional regulator, TetR family
HMFPNEFG_01699 4.3e-13 K Transcriptional regulator, TetR family
HMFPNEFG_01701 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMFPNEFG_01702 3e-86
HMFPNEFG_01703 4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMFPNEFG_01704 2.5e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMFPNEFG_01705 9.3e-261 nox C NADH oxidase
HMFPNEFG_01706 1.1e-86 hmpT S ECF-type riboflavin transporter, S component
HMFPNEFG_01707 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMFPNEFG_01708 6.1e-48 1.14.12.17 S Cupin 2, conserved barrel domain protein
HMFPNEFG_01709 1.5e-166 yvgN C Aldo keto reductase
HMFPNEFG_01710 6.6e-136 puuD S peptidase C26
HMFPNEFG_01711 8.1e-257 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HMFPNEFG_01712 2.5e-209 yfeO P Voltage gated chloride channel
HMFPNEFG_01713 5.3e-226 sptS 2.7.13.3 T Histidine kinase
HMFPNEFG_01714 3.3e-118 K response regulator
HMFPNEFG_01715 1.7e-87 2.7.6.5 T Region found in RelA / SpoT proteins
HMFPNEFG_01716 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMFPNEFG_01717 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMFPNEFG_01718 1.1e-256 malT G Major Facilitator
HMFPNEFG_01719 2e-48 L PFAM transposase IS200-family protein
HMFPNEFG_01720 6.3e-213 phbA 2.3.1.9 I Belongs to the thiolase family
HMFPNEFG_01721 1.5e-172 malR K Transcriptional regulator, LacI family
HMFPNEFG_01722 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMFPNEFG_01723 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMFPNEFG_01724 7.2e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMFPNEFG_01725 3.1e-104 wecD3 K PFAM GCN5-related N-acetyltransferase
HMFPNEFG_01727 0.0 clpL O associated with various cellular activities
HMFPNEFG_01728 7.8e-32
HMFPNEFG_01729 6.1e-216 patA 2.6.1.1 E Aminotransferase
HMFPNEFG_01730 8e-177 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMFPNEFG_01731 5e-75 osmC O OsmC-like protein
HMFPNEFG_01732 2.6e-126 L Transposase and inactivated derivatives IS30 family
HMFPNEFG_01733 5.9e-30 2.7.13.3 T GHKL domain
HMFPNEFG_01736 1.3e-260 S Putative peptidoglycan binding domain
HMFPNEFG_01737 3.5e-35
HMFPNEFG_01738 2.5e-212 bacI V MacB-like periplasmic core domain
HMFPNEFG_01739 4.4e-129 V ABC transporter
HMFPNEFG_01740 5.7e-144 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMFPNEFG_01741 8.9e-259 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMFPNEFG_01742 7.3e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HMFPNEFG_01743 9.4e-149 E Glyoxalase-like domain
HMFPNEFG_01744 7.5e-155 glcU U sugar transport
HMFPNEFG_01745 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HMFPNEFG_01746 2.9e-96 S reductase
HMFPNEFG_01748 1.1e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMFPNEFG_01749 4.7e-177 ABC-SBP S ABC transporter
HMFPNEFG_01750 1.6e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HMFPNEFG_01751 1.7e-206 htrA 3.4.21.107 O serine protease
HMFPNEFG_01752 4.5e-154 vicX 3.1.26.11 S domain protein
HMFPNEFG_01753 2.7e-149 yycI S YycH protein
HMFPNEFG_01754 2.1e-246 yycH S YycH protein
HMFPNEFG_01755 0.0 vicK 2.7.13.3 T Histidine kinase
HMFPNEFG_01756 6.8e-130 K response regulator
HMFPNEFG_01758 2.1e-310 lmrA 3.6.3.44 V ABC transporter
HMFPNEFG_01759 3.3e-74 K helix_turn_helix multiple antibiotic resistance protein
HMFPNEFG_01761 9.8e-09 K DNA-binding helix-turn-helix protein
HMFPNEFG_01762 7.2e-69 S Bacterial membrane protein, YfhO
HMFPNEFG_01764 1.6e-58 acmD 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMFPNEFG_01765 1.7e-79 csd1 3.5.1.28 G domain, Protein
HMFPNEFG_01766 1.8e-128 ykoT GT2 M Glycosyl transferase family 2
HMFPNEFG_01767 2.5e-60 S integral membrane protein
HMFPNEFG_01768 2.6e-79 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMFPNEFG_01769 1.3e-34 S Acyltransferase family
HMFPNEFG_01770 7.3e-58 O Bacterial dnaA protein
HMFPNEFG_01771 1.8e-106 cfr9IM 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMFPNEFG_01772 8.2e-68
HMFPNEFG_01773 1e-47
HMFPNEFG_01774 1.1e-153 D CobQ CobB MinD ParA nucleotide binding domain protein
HMFPNEFG_01775 4.5e-58 L Resolvase, N terminal domain
HMFPNEFG_01776 4.9e-56 V Domain of unknown function (DUF3883)
HMFPNEFG_01779 1.6e-40
HMFPNEFG_01781 1e-27 cspA K Cold shock protein
HMFPNEFG_01782 2.7e-26 K TRANSCRIPTIONal
HMFPNEFG_01783 2.2e-36 pldB 3.1.1.5 I Serine aminopeptidase, S33
HMFPNEFG_01784 3.1e-13 pldB 3.1.1.5 I Serine aminopeptidase, S33
HMFPNEFG_01785 5.6e-79 pncA Q Isochorismatase family
HMFPNEFG_01786 4e-230 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMFPNEFG_01787 4.2e-111 3.6.1.13, 3.6.1.55 F NUDIX domain
HMFPNEFG_01788 6.3e-85 L Psort location Cytoplasmic, score
HMFPNEFG_01790 2.6e-191 nss M transferase activity, transferring glycosyl groups
HMFPNEFG_01791 2.2e-144 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
HMFPNEFG_01792 2.6e-195 M transferase activity, transferring glycosyl groups
HMFPNEFG_01793 1.2e-216 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
HMFPNEFG_01794 5e-154 asp3 S Accessory Sec secretory system ASP3
HMFPNEFG_01795 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMFPNEFG_01796 1.1e-225 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
HMFPNEFG_01797 4.6e-196 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
HMFPNEFG_01799 3.6e-17 sraP UW this gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMFPNEFG_01800 7e-08 UW Hep Hag repeat protein
HMFPNEFG_01802 3.3e-97 busR K UTRA
HMFPNEFG_01803 3.8e-166 yegU O ADP-ribosylglycohydrolase
HMFPNEFG_01804 3.5e-239 F Belongs to the purine-cytosine permease (2.A.39) family
HMFPNEFG_01805 1.5e-118 G Belongs to the carbohydrate kinase PfkB family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)