ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHMJEDOE_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_00002 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HHMJEDOE_00003 1.3e-61 yngL S Protein of unknown function (DUF1360)
HHMJEDOE_00004 2.2e-290 yngK T Glycosyl hydrolase-like 10
HHMJEDOE_00005 6.1e-205 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HHMJEDOE_00006 1.4e-306 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHMJEDOE_00007 4e-240 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HHMJEDOE_00008 6.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HHMJEDOE_00009 1.6e-155 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HHMJEDOE_00010 1.2e-124 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HHMJEDOE_00011 1.7e-279 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHMJEDOE_00012 1e-226 nrnB S phosphohydrolase (DHH superfamily)
HHMJEDOE_00013 1.2e-101 yngC S membrane-associated protein
HHMJEDOE_00014 4.9e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHMJEDOE_00015 2.5e-68 yngA S membrane
HHMJEDOE_00016 1.4e-204 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHMJEDOE_00017 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_00018 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_00019 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_00020 5.6e-286 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HHMJEDOE_00021 1.5e-239 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HHMJEDOE_00022 1.3e-207 S Platelet-activating factor acetylhydrolase, isoform II
HHMJEDOE_00024 2.6e-275 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HHMJEDOE_00025 4.8e-244 agcS E Sodium alanine symporter
HHMJEDOE_00026 3.6e-55 ynfC
HHMJEDOE_00027 2.3e-12
HHMJEDOE_00028 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHMJEDOE_00029 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHMJEDOE_00030 9.9e-65 yccU S CoA-binding protein
HHMJEDOE_00031 1.2e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHMJEDOE_00032 5.9e-48 yneR S Belongs to the HesB IscA family
HHMJEDOE_00033 1.1e-52 yneQ
HHMJEDOE_00034 1.2e-73 yneP S Thioesterase-like superfamily
HHMJEDOE_00035 8.6e-35 tlp S Belongs to the Tlp family
HHMJEDOE_00036 4e-08 sspN S Small acid-soluble spore protein N family
HHMJEDOE_00038 4.1e-84 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HHMJEDOE_00039 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HHMJEDOE_00040 3.8e-14 sspO S Belongs to the SspO family
HHMJEDOE_00041 3.9e-19 sspP S Belongs to the SspP family
HHMJEDOE_00042 3.3e-59 hspX O Spore coat protein
HHMJEDOE_00043 1.4e-69 yneK S Protein of unknown function (DUF2621)
HHMJEDOE_00044 3.6e-74 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HHMJEDOE_00045 8.8e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HHMJEDOE_00046 1.2e-123 ccdA O cytochrome c biogenesis protein
HHMJEDOE_00047 1.2e-14 ynzD S Spo0E like sporulation regulatory protein
HHMJEDOE_00048 1.8e-28 yneF S UPF0154 protein
HHMJEDOE_00049 1.7e-78 yneE S Sporulation inhibitor of replication protein sirA
HHMJEDOE_00050 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHMJEDOE_00051 1.6e-30 ynzC S UPF0291 protein
HHMJEDOE_00052 5.6e-110 yneB L resolvase
HHMJEDOE_00053 1.4e-47 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HHMJEDOE_00054 6.4e-108 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHMJEDOE_00055 1.4e-69 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HHMJEDOE_00056 1.4e-74 yndM S Protein of unknown function (DUF2512)
HHMJEDOE_00057 5.3e-128 yndL S Replication protein
HHMJEDOE_00059 1.6e-270 yndJ S YndJ-like protein
HHMJEDOE_00060 6e-85 yndH S Domain of unknown function (DUF4166)
HHMJEDOE_00061 1.1e-134 yndG S DoxX-like family
HHMJEDOE_00062 1e-189 gerLC S Spore germination protein
HHMJEDOE_00063 2e-184 gerAB U Spore germination
HHMJEDOE_00064 1.1e-268 gerAA EG Spore germination protein
HHMJEDOE_00065 6.9e-175 chrA P chromate transporter, chromate ion transporter
HHMJEDOE_00068 4.1e-69 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HHMJEDOE_00069 1.5e-65
HHMJEDOE_00070 4.3e-23 tatA U protein secretion
HHMJEDOE_00074 1.9e-122 S Domain of unknown function, YrpD
HHMJEDOE_00078 2.4e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHMJEDOE_00079 6.1e-07 S Protein of unknown function (DUF1643)
HHMJEDOE_00080 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HHMJEDOE_00081 5.7e-69 yncE S Protein of unknown function (DUF2691)
HHMJEDOE_00083 1.9e-201 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHMJEDOE_00084 3.2e-35 iolT EGP Major facilitator Superfamily
HHMJEDOE_00085 7.1e-104 yrkJ S membrane transporter protein
HHMJEDOE_00086 7.3e-33 yrkI O Belongs to the sulfur carrier protein TusA family
HHMJEDOE_00087 1.4e-196 yrkH P Rhodanese Homology Domain
HHMJEDOE_00088 2.5e-57 perX S DsrE/DsrF-like family
HHMJEDOE_00089 4e-85 yrkF OP Belongs to the sulfur carrier protein TusA family
HHMJEDOE_00090 1.7e-52 P Rhodanese Homology Domain
HHMJEDOE_00091 2.8e-70 yrkE O DsrE/DsrF/DrsH-like family
HHMJEDOE_00092 7.8e-39 yrkD S protein conserved in bacteria
HHMJEDOE_00093 6.7e-28
HHMJEDOE_00094 4.9e-08 3.2.1.8 G Glycosyl hydrolases family 11
HHMJEDOE_00095 2.7e-277 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HHMJEDOE_00096 4e-248 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HHMJEDOE_00097 2.2e-210 xylR GK ROK family
HHMJEDOE_00098 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HHMJEDOE_00099 3.9e-246 xynT G MFS/sugar transport protein
HHMJEDOE_00100 4.4e-73 yhbS S family acetyltransferase
HHMJEDOE_00101 2.1e-71 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HHMJEDOE_00104 8.9e-100 ynaE S Domain of unknown function (DUF3885)
HHMJEDOE_00105 0.0 pps 2.7.9.2 GT Phosphoenolpyruvate synthase
HHMJEDOE_00106 3.7e-124 ynaC
HHMJEDOE_00107 5.3e-63 G SMI1-KNR4 cell-wall
HHMJEDOE_00108 2.4e-53
HHMJEDOE_00109 7.8e-36
HHMJEDOE_00110 6.7e-106 yokF 3.1.31.1 L RNA catabolic process
HHMJEDOE_00111 8.7e-126 rsbW 2.4.1.12, 2.7.11.1 GT2 T sigma factor antagonist activity
HHMJEDOE_00112 8.7e-283 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HHMJEDOE_00113 2.3e-81 S SMI1-KNR4 cell-wall
HHMJEDOE_00114 2.6e-124 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHMJEDOE_00115 3.5e-31 xhlB S SPP1 phage holin
HHMJEDOE_00116 3e-28 bhlA S BhlA holin family
HHMJEDOE_00119 1.6e-62
HHMJEDOE_00122 3.4e-59
HHMJEDOE_00123 1.3e-219 NU Prophage endopeptidase tail
HHMJEDOE_00124 4.1e-105 S Phage tail protein
HHMJEDOE_00125 0.0 D phage tail tape measure protein
HHMJEDOE_00128 2e-77 S Phage tail tube protein
HHMJEDOE_00130 2e-49 S Bacteriophage HK97-gp10, putative tail-component
HHMJEDOE_00131 1e-37 S Phage head-tail joining protein
HHMJEDOE_00132 4.8e-40 S Phage gp6-like head-tail connector protein
HHMJEDOE_00133 1.9e-19
HHMJEDOE_00134 3.5e-156 gp36 S capsid protein
HHMJEDOE_00135 4.4e-80 S peptidase activity
HHMJEDOE_00136 2.4e-173 S Phage portal protein
HHMJEDOE_00137 4.3e-303 S Terminase
HHMJEDOE_00138 4e-79 L phage terminase small subunit
HHMJEDOE_00139 1.7e-47 V HNH endonuclease
HHMJEDOE_00140 5.5e-44 T Histidine kinase
HHMJEDOE_00144 1.7e-58
HHMJEDOE_00148 2.3e-79
HHMJEDOE_00149 2.3e-93 S nuclease activity
HHMJEDOE_00150 4.9e-62
HHMJEDOE_00151 0.0 S hydrolase activity
HHMJEDOE_00152 2.4e-72 S Protein of unknown function (DUF669)
HHMJEDOE_00154 3.1e-162 tadZ D AAA domain
HHMJEDOE_00155 1.2e-92 S DNA protection
HHMJEDOE_00158 6.1e-18 S Uncharacterized protein YqaH
HHMJEDOE_00160 9.7e-20
HHMJEDOE_00161 4.8e-52 S Phage regulatory protein Rha (Phage_pRha)
HHMJEDOE_00163 1.1e-12 K sequence-specific DNA binding
HHMJEDOE_00164 3.7e-50 1.15.1.2 E Pfam:DUF955
HHMJEDOE_00165 1.4e-135 L Belongs to the 'phage' integrase family
HHMJEDOE_00166 4.3e-258 glnA 6.3.1.2 E glutamine synthetase
HHMJEDOE_00167 1.1e-68 glnR K transcriptional
HHMJEDOE_00168 1.7e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HHMJEDOE_00169 1.3e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHMJEDOE_00170 1.2e-174 spoVK O stage V sporulation protein K
HHMJEDOE_00171 1.5e-109 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHMJEDOE_00172 3.7e-103 ymaB
HHMJEDOE_00173 1.2e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHMJEDOE_00174 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHMJEDOE_00175 1.5e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HHMJEDOE_00176 1.3e-21 ymzA
HHMJEDOE_00177 5.1e-25
HHMJEDOE_00178 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HHMJEDOE_00179 1.2e-169 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHMJEDOE_00180 8.1e-43 ymaF S YmaF family
HHMJEDOE_00182 5.9e-49 ebrA P Small Multidrug Resistance protein
HHMJEDOE_00183 1.6e-50 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HHMJEDOE_00184 3.1e-75 ymaD O redox protein, regulator of disulfide bond formation
HHMJEDOE_00185 2.6e-121 ymaC S Replication protein
HHMJEDOE_00186 1.1e-07 K Transcriptional regulator
HHMJEDOE_00187 4.3e-242 aprX O Belongs to the peptidase S8 family
HHMJEDOE_00188 3.7e-151 ymaE S Metallo-beta-lactamase superfamily
HHMJEDOE_00189 5.1e-57 ymzB
HHMJEDOE_00190 1.4e-223 cypA C Cytochrome P450
HHMJEDOE_00191 0.0 pks13 HQ Beta-ketoacyl synthase
HHMJEDOE_00192 0.0 dhbF IQ polyketide synthase
HHMJEDOE_00193 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HHMJEDOE_00194 0.0 pfaA Q Polyketide synthase of type I
HHMJEDOE_00195 0.0 rhiB IQ polyketide synthase
HHMJEDOE_00196 1.6e-129 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HHMJEDOE_00197 4.2e-133 pksH 4.2.1.18 I enoyl-CoA hydratase
HHMJEDOE_00198 4.6e-238 pksG 2.3.3.10 I synthase
HHMJEDOE_00199 5.6e-220 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHMJEDOE_00200 4.1e-37 acpK IQ Phosphopantetheine attachment site
HHMJEDOE_00201 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHMJEDOE_00202 5.1e-160 pksD Q Acyl transferase domain
HHMJEDOE_00203 2.5e-150 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHMJEDOE_00204 3.1e-119 pksB 3.1.2.6 S Polyketide biosynthesis
HHMJEDOE_00205 6.7e-97 pksA K Transcriptional regulator
HHMJEDOE_00206 2.7e-89 ymcC S Membrane
HHMJEDOE_00207 6.2e-52 S Regulatory protein YrvL
HHMJEDOE_00208 2.4e-16 plnP S CAAX protease self-immunity
HHMJEDOE_00209 1.8e-13 plnP S CAAX protease self-immunity
HHMJEDOE_00210 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHMJEDOE_00211 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHMJEDOE_00212 2.2e-88 cotE S Spore coat protein
HHMJEDOE_00213 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HHMJEDOE_00214 9.4e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HHMJEDOE_00215 1.5e-206 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HHMJEDOE_00216 1.6e-180 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HHMJEDOE_00217 1.2e-36 spoVS S Stage V sporulation protein S
HHMJEDOE_00218 7.4e-149 ymdB S protein conserved in bacteria
HHMJEDOE_00219 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HHMJEDOE_00220 6.1e-200 pbpX V Beta-lactamase
HHMJEDOE_00221 4.9e-185 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHMJEDOE_00222 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
HHMJEDOE_00223 4.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHMJEDOE_00224 1.7e-120 ymfM S protein conserved in bacteria
HHMJEDOE_00225 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HHMJEDOE_00226 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HHMJEDOE_00227 1.7e-120 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HHMJEDOE_00228 2e-236 ymfH S zinc protease
HHMJEDOE_00229 2.1e-222 ymfF S Peptidase M16
HHMJEDOE_00230 2.2e-200 ymfD EGP Major facilitator Superfamily
HHMJEDOE_00231 2.8e-131 ymfC K Transcriptional regulator
HHMJEDOE_00232 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHMJEDOE_00233 2.2e-31 S YlzJ-like protein
HHMJEDOE_00234 2.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HHMJEDOE_00235 2.4e-306 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHMJEDOE_00236 1.7e-154 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HHMJEDOE_00237 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HHMJEDOE_00238 7.8e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HHMJEDOE_00239 3.7e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HHMJEDOE_00240 8.6e-146 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HHMJEDOE_00241 1.1e-40 ymxH S YlmC YmxH family
HHMJEDOE_00242 7e-231 pepR S Belongs to the peptidase M16 family
HHMJEDOE_00243 5e-176 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HHMJEDOE_00244 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HHMJEDOE_00245 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHMJEDOE_00246 8.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHMJEDOE_00247 1.2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHMJEDOE_00248 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHMJEDOE_00249 8.6e-44 ylxP S protein conserved in bacteria
HHMJEDOE_00250 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHMJEDOE_00251 3.1e-47 ylxQ J ribosomal protein
HHMJEDOE_00252 3.2e-35 ylxR K nucleic-acid-binding protein implicated in transcription termination
HHMJEDOE_00253 1.6e-202 nusA K Participates in both transcription termination and antitermination
HHMJEDOE_00254 2.1e-79 rimP S Required for maturation of 30S ribosomal subunits
HHMJEDOE_00255 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHMJEDOE_00256 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHMJEDOE_00257 7.2e-231 rasP M zinc metalloprotease
HHMJEDOE_00258 1.4e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HHMJEDOE_00259 5.5e-136 cdsA 2.7.7.41 S Belongs to the CDS family
HHMJEDOE_00260 6e-143 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHMJEDOE_00261 4.2e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHMJEDOE_00262 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHMJEDOE_00263 3.8e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHMJEDOE_00264 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HHMJEDOE_00265 1.4e-60 ylxL
HHMJEDOE_00266 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_00267 3.6e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HHMJEDOE_00268 4.1e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HHMJEDOE_00269 1.2e-77 cheW NT COG0835 Chemotaxis signal transduction protein
HHMJEDOE_00270 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HHMJEDOE_00271 6e-186 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HHMJEDOE_00272 9.5e-153 flhG D Belongs to the ParA family
HHMJEDOE_00273 1.8e-185 flhF N Flagellar biosynthesis regulator FlhF
HHMJEDOE_00274 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHMJEDOE_00275 6.4e-188 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HHMJEDOE_00276 3.4e-130 fliR N Flagellar biosynthetic protein FliR
HHMJEDOE_00277 3.3e-35 fliQ N Role in flagellar biosynthesis
HHMJEDOE_00278 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HHMJEDOE_00279 4.8e-93 fliZ N Flagellar biosynthesis protein, FliO
HHMJEDOE_00280 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HHMJEDOE_00281 5.8e-163 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HHMJEDOE_00282 9.2e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHMJEDOE_00283 1.3e-46 fliL N Controls the rotational direction of flagella during chemotaxis
HHMJEDOE_00284 1.9e-136 flgG N Flagellar basal body rod
HHMJEDOE_00285 8.1e-62 flgD N Flagellar basal body rod modification protein
HHMJEDOE_00286 1.3e-170 fliK N Flagellar hook-length control protein
HHMJEDOE_00287 1.8e-33 ylxF S MgtE intracellular N domain
HHMJEDOE_00288 2.7e-68 fliJ N Flagellar biosynthesis chaperone
HHMJEDOE_00289 9.8e-239 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HHMJEDOE_00290 1.1e-101 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HHMJEDOE_00291 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HHMJEDOE_00292 3.1e-247 fliF N The M ring may be actively involved in energy transduction
HHMJEDOE_00293 3.5e-28 fliE N Flagellar hook-basal body
HHMJEDOE_00294 5.8e-74 flgC N Belongs to the flagella basal body rod proteins family
HHMJEDOE_00295 2.2e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HHMJEDOE_00296 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HHMJEDOE_00297 1.4e-238 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHMJEDOE_00298 5.7e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHMJEDOE_00299 2.2e-168 xerC L tyrosine recombinase XerC
HHMJEDOE_00300 9.1e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HHMJEDOE_00301 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHMJEDOE_00302 2.8e-152 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HHMJEDOE_00303 1.2e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HHMJEDOE_00304 2.2e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HHMJEDOE_00305 1.5e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HHMJEDOE_00306 8e-257 ylqG
HHMJEDOE_00307 2.7e-124 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHMJEDOE_00308 2.7e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHMJEDOE_00309 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHMJEDOE_00310 7.3e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHMJEDOE_00311 4.2e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHMJEDOE_00312 3.1e-60 ylqD S YlqD protein
HHMJEDOE_00313 1.7e-35 ylqC S Belongs to the UPF0109 family
HHMJEDOE_00314 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHMJEDOE_00315 4.3e-234 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHMJEDOE_00316 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHMJEDOE_00317 6.2e-82
HHMJEDOE_00318 2.3e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHMJEDOE_00319 0.0 smc D Required for chromosome condensation and partitioning
HHMJEDOE_00320 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHMJEDOE_00321 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHMJEDOE_00322 3.9e-128 IQ reductase
HHMJEDOE_00323 2.1e-166 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HHMJEDOE_00324 1.3e-174 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHMJEDOE_00325 3.7e-78 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HHMJEDOE_00326 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHMJEDOE_00327 2.1e-152 sdaAA 4.3.1.17 E L-serine dehydratase
HHMJEDOE_00328 6.2e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HHMJEDOE_00329 1.1e-292 yloV S kinase related to dihydroxyacetone kinase
HHMJEDOE_00330 5.5e-59 asp S protein conserved in bacteria
HHMJEDOE_00331 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHMJEDOE_00332 6.7e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHMJEDOE_00333 1e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHMJEDOE_00334 6.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHMJEDOE_00335 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HHMJEDOE_00336 4.8e-137 stp 3.1.3.16 T phosphatase
HHMJEDOE_00337 1.9e-203 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HHMJEDOE_00338 2.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHMJEDOE_00339 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHMJEDOE_00340 1.6e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHMJEDOE_00341 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHMJEDOE_00342 1.4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHMJEDOE_00343 8.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHMJEDOE_00344 1.2e-109 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HHMJEDOE_00345 1.5e-40 ylzA S Belongs to the UPF0296 family
HHMJEDOE_00346 2.1e-152 yloC S stress-induced protein
HHMJEDOE_00347 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HHMJEDOE_00348 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HHMJEDOE_00349 4.5e-72 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HHMJEDOE_00350 1.8e-139 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HHMJEDOE_00351 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HHMJEDOE_00352 4e-107 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HHMJEDOE_00353 6.3e-218 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HHMJEDOE_00354 1.1e-174 cysP P phosphate transporter
HHMJEDOE_00355 1.2e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HHMJEDOE_00356 8.3e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHMJEDOE_00357 4.2e-119 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHMJEDOE_00358 8.9e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HHMJEDOE_00359 3.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HHMJEDOE_00360 0.0 carB 6.3.5.5 F Belongs to the CarB family
HHMJEDOE_00361 1.1e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHMJEDOE_00362 6.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HHMJEDOE_00363 1.1e-159 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HHMJEDOE_00364 6.7e-232 pyrP F Xanthine uracil
HHMJEDOE_00365 5.2e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHMJEDOE_00366 1.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHMJEDOE_00367 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHMJEDOE_00368 8e-61 dksA T COG1734 DnaK suppressor protein
HHMJEDOE_00370 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHMJEDOE_00371 4.4e-67 divIVA D Cell division initiation protein
HHMJEDOE_00372 1.9e-133 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HHMJEDOE_00373 1.3e-39 yggT S membrane
HHMJEDOE_00374 6.9e-59 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHMJEDOE_00375 3.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HHMJEDOE_00376 1e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HHMJEDOE_00377 3.1e-37 ylmC S sporulation protein
HHMJEDOE_00378 1.3e-235 argE 3.5.1.16 E Acetylornithine deacetylase
HHMJEDOE_00379 3.9e-142 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HHMJEDOE_00380 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_00381 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_00382 9.5e-167 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HHMJEDOE_00383 0.0 bpr O COG1404 Subtilisin-like serine proteases
HHMJEDOE_00384 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHMJEDOE_00385 1.6e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHMJEDOE_00386 6.2e-58 sbp S small basic protein
HHMJEDOE_00387 9.4e-113 ylxX S protein conserved in bacteria
HHMJEDOE_00388 5.9e-102 ylxW S protein conserved in bacteria
HHMJEDOE_00389 1.1e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHMJEDOE_00390 1.7e-165 murB 1.3.1.98 M cell wall formation
HHMJEDOE_00391 4.1e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHMJEDOE_00392 2.2e-185 spoVE D Belongs to the SEDS family
HHMJEDOE_00393 3.7e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHMJEDOE_00394 5.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHMJEDOE_00395 1.4e-273 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHMJEDOE_00396 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HHMJEDOE_00397 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHMJEDOE_00398 7.8e-42 ftsL D Essential cell division protein
HHMJEDOE_00399 1.5e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHMJEDOE_00400 2.9e-78 mraZ K Belongs to the MraZ family
HHMJEDOE_00401 6.9e-295 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HHMJEDOE_00402 1.3e-154 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHMJEDOE_00403 1.6e-85 ylbP K n-acetyltransferase
HHMJEDOE_00404 1.3e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HHMJEDOE_00405 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHMJEDOE_00406 3.6e-88 yceD S metal-binding, possibly nucleic acid-binding protein
HHMJEDOE_00408 2e-217 ylbM S Belongs to the UPF0348 family
HHMJEDOE_00409 1.1e-181 ylbL T Belongs to the peptidase S16 family
HHMJEDOE_00410 2.4e-136 ylbK S esterase of the alpha-beta hydrolase superfamily
HHMJEDOE_00411 1.7e-213 ylbJ S Sporulation integral membrane protein YlbJ
HHMJEDOE_00412 5.6e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHMJEDOE_00413 9.2e-98 rsmD 2.1.1.171 L Methyltransferase
HHMJEDOE_00414 9.8e-39 ylbG S UPF0298 protein
HHMJEDOE_00415 5.2e-75 ylbF S Belongs to the UPF0342 family
HHMJEDOE_00416 1.5e-36 ylbE S YlbE-like protein
HHMJEDOE_00417 1.2e-59 ylbD S Putative coat protein
HHMJEDOE_00418 1.1e-195 ylbC S protein with SCP PR1 domains
HHMJEDOE_00419 2.6e-74 ylbB T COG0517 FOG CBS domain
HHMJEDOE_00420 2.2e-60 ylbA S YugN-like family
HHMJEDOE_00421 2.9e-162 ctaG S cytochrome c oxidase
HHMJEDOE_00422 1.7e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HHMJEDOE_00423 7.4e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HHMJEDOE_00424 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHMJEDOE_00425 7.1e-187 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HHMJEDOE_00426 5.5e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHMJEDOE_00427 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HHMJEDOE_00428 1e-136 phr 4.1.99.3 L Belongs to the DNA photolyase family
HHMJEDOE_00429 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HHMJEDOE_00430 3.3e-209 ftsW D Belongs to the SEDS family
HHMJEDOE_00431 1.9e-43 ylaN S Belongs to the UPF0358 family
HHMJEDOE_00432 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
HHMJEDOE_00433 1.1e-78 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HHMJEDOE_00434 5.2e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HHMJEDOE_00435 5.4e-86 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHMJEDOE_00436 7.3e-32 ylaI S protein conserved in bacteria
HHMJEDOE_00437 3.6e-46 ylaH S YlaH-like protein
HHMJEDOE_00438 0.0 typA T GTP-binding protein TypA
HHMJEDOE_00439 1.8e-21 S Family of unknown function (DUF5325)
HHMJEDOE_00440 3.6e-34 ylaE
HHMJEDOE_00441 1.4e-12 sigC S Putative zinc-finger
HHMJEDOE_00442 7.6e-86 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_00443 2.1e-39 ylaB
HHMJEDOE_00444 0.0 ylaA
HHMJEDOE_00445 6.3e-285 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HHMJEDOE_00446 1.3e-31 K Transcriptional regulator
HHMJEDOE_00447 2.3e-50 I Carboxylesterase family
HHMJEDOE_00448 1.7e-149 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HHMJEDOE_00449 2.7e-74 ykzC S Acetyltransferase (GNAT) family
HHMJEDOE_00450 1.7e-145 suhB 3.1.3.25 G Inositol monophosphatase
HHMJEDOE_00451 9.3e-26 ykzI
HHMJEDOE_00452 6.6e-116 yktB S Belongs to the UPF0637 family
HHMJEDOE_00453 1e-41 yktA S Belongs to the UPF0223 family
HHMJEDOE_00454 6.1e-274 speA 4.1.1.19 E Arginine
HHMJEDOE_00455 2.7e-10 S SR1 protein
HHMJEDOE_00456 1.8e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HHMJEDOE_00457 2e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHMJEDOE_00458 1.1e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHMJEDOE_00459 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHMJEDOE_00460 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHMJEDOE_00461 1.1e-100 recN L Putative cell-wall binding lipoprotein
HHMJEDOE_00463 8.3e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHMJEDOE_00464 3.4e-141 ykrA S hydrolases of the HAD superfamily
HHMJEDOE_00465 4.1e-30 ykzG S Belongs to the UPF0356 family
HHMJEDOE_00466 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHMJEDOE_00467 3.5e-305 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HHMJEDOE_00468 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HHMJEDOE_00469 2.8e-143 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HHMJEDOE_00470 5.2e-235 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HHMJEDOE_00471 1.9e-43 abrB K of stationary sporulation gene expression
HHMJEDOE_00472 1.9e-181 mreB D Rod-share determining protein MreBH
HHMJEDOE_00473 1.1e-12 S Uncharacterized protein YkpC
HHMJEDOE_00474 9.8e-233 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HHMJEDOE_00475 1e-154 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHMJEDOE_00476 3.2e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHMJEDOE_00477 1.5e-37 ykoA
HHMJEDOE_00478 1.2e-103 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HHMJEDOE_00479 2.4e-310 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HHMJEDOE_00480 1.2e-163 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HHMJEDOE_00481 4.9e-134 fruR K Transcriptional regulator
HHMJEDOE_00482 3.5e-203 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HHMJEDOE_00483 4.1e-119 macB V ABC transporter, ATP-binding protein
HHMJEDOE_00484 1.9e-150 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HHMJEDOE_00485 4.2e-108 yknW S Yip1 domain
HHMJEDOE_00486 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHMJEDOE_00487 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHMJEDOE_00488 9.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HHMJEDOE_00489 5.1e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HHMJEDOE_00490 1.8e-87 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HHMJEDOE_00491 1.9e-234 moeA 2.10.1.1 H molybdopterin
HHMJEDOE_00492 7.4e-186 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHMJEDOE_00493 1.3e-97 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HHMJEDOE_00494 2.1e-105 yknT
HHMJEDOE_00495 3.2e-93 rok K Repressor of ComK
HHMJEDOE_00496 5.1e-78 ykuV CO thiol-disulfide
HHMJEDOE_00497 1.9e-100 ykuU O Alkyl hydroperoxide reductase
HHMJEDOE_00498 1.7e-137 ykuT M Mechanosensitive ion channel
HHMJEDOE_00499 5.8e-36 ykuS S Belongs to the UPF0180 family
HHMJEDOE_00500 3e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HHMJEDOE_00501 5.3e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HHMJEDOE_00502 4e-75 fld C Flavodoxin
HHMJEDOE_00503 2.2e-165 ykuO
HHMJEDOE_00504 6.3e-79 fld C Flavodoxin domain
HHMJEDOE_00505 9.6e-166 ccpC K Transcriptional regulator
HHMJEDOE_00506 1e-75 ykuL S CBS domain
HHMJEDOE_00507 3.9e-27 ykzF S Antirepressor AbbA
HHMJEDOE_00508 2.4e-92 ykuK S Ribonuclease H-like
HHMJEDOE_00509 3.9e-37 ykuJ S protein conserved in bacteria
HHMJEDOE_00510 4.8e-232 ykuI T Diguanylate phosphodiesterase
HHMJEDOE_00511 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_00512 1.4e-156 ykuE S Metallophosphoesterase
HHMJEDOE_00513 9.7e-84 ykuD S protein conserved in bacteria
HHMJEDOE_00514 2.7e-233 ykuC EGP Major facilitator Superfamily
HHMJEDOE_00515 4.9e-84 ykyB S YkyB-like protein
HHMJEDOE_00516 1.2e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
HHMJEDOE_00517 4.9e-15
HHMJEDOE_00518 2e-219 patA 2.6.1.1 E Aminotransferase
HHMJEDOE_00519 0.0 pilS 2.7.13.3 T Histidine kinase
HHMJEDOE_00520 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HHMJEDOE_00521 2.1e-114 ykwD J protein with SCP PR1 domains
HHMJEDOE_00522 3.1e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HHMJEDOE_00523 3.4e-235 mcpC NT chemotaxis protein
HHMJEDOE_00524 2.9e-117 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_00525 4.1e-200 splB 4.1.99.14 L Spore photoproduct lyase
HHMJEDOE_00526 7.2e-39 splA S Transcriptional regulator
HHMJEDOE_00527 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHMJEDOE_00528 3.6e-39 ptsH G phosphocarrier protein HPr
HHMJEDOE_00529 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_00530 2.7e-125 glcT K antiterminator
HHMJEDOE_00531 1.1e-162 ykvZ 5.1.1.1 K Transcriptional regulator
HHMJEDOE_00533 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HHMJEDOE_00535 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HHMJEDOE_00536 2.8e-85 stoA CO thiol-disulfide
HHMJEDOE_00537 7.9e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_00538 1.8e-94 ykvT 3.5.1.28 M Cell Wall Hydrolase
HHMJEDOE_00539 5.2e-27
HHMJEDOE_00540 1.7e-24 ykvS S protein conserved in bacteria
HHMJEDOE_00541 3.8e-42 ykvR S Protein of unknown function (DUF3219)
HHMJEDOE_00542 3.4e-36 yoaW
HHMJEDOE_00543 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HHMJEDOE_00544 1.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HHMJEDOE_00545 8.1e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HHMJEDOE_00546 3.6e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HHMJEDOE_00547 5.5e-176 ykvI S membrane
HHMJEDOE_00548 0.0 clpE O Belongs to the ClpA ClpB family
HHMJEDOE_00549 1.4e-137 motA N flagellar motor
HHMJEDOE_00550 1.3e-124 motB N Flagellar motor protein
HHMJEDOE_00551 1.3e-75 ykvE K transcriptional
HHMJEDOE_00552 3e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HHMJEDOE_00553 8e-57 eag
HHMJEDOE_00554 6.4e-09 S Spo0E like sporulation regulatory protein
HHMJEDOE_00555 2.5e-47 XK27_09985 S Protein of unknown function (DUF1232)
HHMJEDOE_00556 1.3e-93 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HHMJEDOE_00557 2.4e-110 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HHMJEDOE_00558 1.1e-130 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HHMJEDOE_00559 7.4e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HHMJEDOE_00560 1.1e-223 mtnE 2.6.1.83 E Aminotransferase
HHMJEDOE_00561 4.2e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHMJEDOE_00562 1.7e-221 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HHMJEDOE_00563 2.7e-191 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HHMJEDOE_00565 3.2e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHMJEDOE_00566 0.0 kinE 2.7.13.3 T Histidine kinase
HHMJEDOE_00567 5e-182 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HHMJEDOE_00568 2e-19 ykzE
HHMJEDOE_00569 3.5e-10 ydfR S Protein of unknown function (DUF421)
HHMJEDOE_00570 3.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HHMJEDOE_00571 2.1e-152 htpX O Belongs to the peptidase M48B family
HHMJEDOE_00572 7e-119 ykrK S Domain of unknown function (DUF1836)
HHMJEDOE_00573 1.9e-26 sspD S small acid-soluble spore protein
HHMJEDOE_00574 5.7e-110 rsgI S Anti-sigma factor N-terminus
HHMJEDOE_00575 1.8e-128 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_00576 2.3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HHMJEDOE_00577 2.3e-108 ykoX S membrane-associated protein
HHMJEDOE_00578 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HHMJEDOE_00579 4.4e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HHMJEDOE_00580 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HHMJEDOE_00581 4.6e-180 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHMJEDOE_00582 0.0 ykoS
HHMJEDOE_00583 5.2e-150 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HHMJEDOE_00584 3.6e-93 ykoP G polysaccharide deacetylase
HHMJEDOE_00585 3.2e-190 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HHMJEDOE_00586 3e-81 mhqR K transcriptional
HHMJEDOE_00587 9.4e-23 ykoL
HHMJEDOE_00588 3.5e-18
HHMJEDOE_00589 1.4e-53 tnrA K transcriptional
HHMJEDOE_00590 4.9e-217 mgtE P Acts as a magnesium transporter
HHMJEDOE_00593 1.9e-73 ykoJ S Peptidase propeptide and YPEB domain
HHMJEDOE_00594 2.9e-85 ykoI S Peptidase propeptide and YPEB domain
HHMJEDOE_00595 2.5e-229 ykoH 2.7.13.3 T Histidine kinase
HHMJEDOE_00596 2.8e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_00597 2.9e-105 ykoF S YKOF-related Family
HHMJEDOE_00598 6.7e-94 ykoE S ABC-type cobalt transport system, permease component
HHMJEDOE_00599 4e-282 P ABC transporter, ATP-binding protein
HHMJEDOE_00600 9e-128 ykoC P Cobalt transport protein
HHMJEDOE_00601 1.7e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHMJEDOE_00602 2.3e-173 isp O Belongs to the peptidase S8 family
HHMJEDOE_00603 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HHMJEDOE_00604 4.8e-79 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HHMJEDOE_00605 1.7e-159 M Glycosyl transferase family 2
HHMJEDOE_00606 2.1e-70 ohrB O Organic hydroperoxide resistance protein
HHMJEDOE_00607 4e-68 ohrR K COG1846 Transcriptional regulators
HHMJEDOE_00608 9.6e-71 ohrA O Organic hydroperoxide resistance protein
HHMJEDOE_00609 5.3e-218 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HHMJEDOE_00610 6.5e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHMJEDOE_00611 9.9e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HHMJEDOE_00612 3.5e-49 ykkD P Multidrug resistance protein
HHMJEDOE_00613 1.3e-49 ykkC P Multidrug resistance protein
HHMJEDOE_00614 1.6e-88 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHMJEDOE_00615 9.7e-89 ykkA S Protein of unknown function (DUF664)
HHMJEDOE_00616 5.6e-127 ykjA S Protein of unknown function (DUF421)
HHMJEDOE_00617 2.5e-09
HHMJEDOE_00618 2.2e-213 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HHMJEDOE_00619 1.9e-90 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HHMJEDOE_00620 2.1e-149 ykgA E Amidinotransferase
HHMJEDOE_00621 1.6e-196 pgl 3.1.1.31 G 6-phosphogluconolactonase
HHMJEDOE_00622 3.3e-183 ykfD E Belongs to the ABC transporter superfamily
HHMJEDOE_00623 5.5e-153 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHMJEDOE_00624 2.2e-188 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HHMJEDOE_00625 1.8e-170 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HHMJEDOE_00626 1.7e-309 dppE E ABC transporter substrate-binding protein
HHMJEDOE_00627 2.1e-180 dppD P Belongs to the ABC transporter superfamily
HHMJEDOE_00628 1.7e-171 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00629 2.9e-157 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00630 4.8e-151 dppA E D-aminopeptidase
HHMJEDOE_00631 3.4e-125 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HHMJEDOE_00632 8.7e-190 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHMJEDOE_00633 1.6e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHMJEDOE_00634 2.4e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHMJEDOE_00635 2.2e-176 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HHMJEDOE_00636 5.4e-237 steT E amino acid
HHMJEDOE_00637 2e-109 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HHMJEDOE_00638 1.6e-172 pit P phosphate transporter
HHMJEDOE_00639 2.2e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HHMJEDOE_00640 5.7e-22 spoIISB S Stage II sporulation protein SB
HHMJEDOE_00641 2e-158 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHMJEDOE_00642 7.4e-37 xhlB S SPP1 phage holin
HHMJEDOE_00643 2.6e-37 xhlA S Haemolysin XhlA
HHMJEDOE_00644 3.2e-134 xepA
HHMJEDOE_00645 1.2e-21 xkdX
HHMJEDOE_00646 4.6e-52 xkdW S XkdW protein
HHMJEDOE_00647 3.1e-308
HHMJEDOE_00648 5.6e-40
HHMJEDOE_00649 5.5e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HHMJEDOE_00650 5.3e-187 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HHMJEDOE_00651 4.5e-68 xkdS S Protein of unknown function (DUF2634)
HHMJEDOE_00652 6.7e-38 xkdR S Protein of unknown function (DUF2577)
HHMJEDOE_00653 3.2e-178 xkdQ G NLP P60 protein
HHMJEDOE_00654 9.6e-116 xkdP S Lysin motif
HHMJEDOE_00655 7.2e-285 xkdO L Transglycosylase SLT domain
HHMJEDOE_00656 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HHMJEDOE_00657 2.3e-75 xkdM S Phage tail tube protein
HHMJEDOE_00658 1.8e-251 xkdK S Phage tail sheath C-terminal domain
HHMJEDOE_00659 2.4e-72 xkdJ
HHMJEDOE_00660 8.1e-82 xkdI S Bacteriophage HK97-gp10, putative tail-component
HHMJEDOE_00661 6.4e-60 yqbH S Domain of unknown function (DUF3599)
HHMJEDOE_00662 7.6e-59 yqbG S Protein of unknown function (DUF3199)
HHMJEDOE_00663 1.3e-168 xkdG S Phage capsid family
HHMJEDOE_00664 4.7e-130 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HHMJEDOE_00665 4.4e-280 yqbA S portal protein
HHMJEDOE_00666 1.4e-245 xtmB S phage terminase, large subunit
HHMJEDOE_00667 8.8e-134 xtmA L phage terminase small subunit
HHMJEDOE_00668 7.2e-81 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HHMJEDOE_00669 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HHMJEDOE_00671 4.9e-111 xkdC L Bacterial dnaA protein
HHMJEDOE_00672 7.1e-142 xkdB K sequence-specific DNA binding
HHMJEDOE_00674 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
HHMJEDOE_00675 6.2e-108 xkdA E IrrE N-terminal-like domain
HHMJEDOE_00676 1.2e-152 ydbD P Catalase
HHMJEDOE_00677 2e-98 yjqB S Pfam:DUF867
HHMJEDOE_00678 2.6e-59 yjqA S Bacterial PH domain
HHMJEDOE_00679 1.6e-161 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HHMJEDOE_00680 1e-35 S YCII-related domain
HHMJEDOE_00682 4.3e-211 S response regulator aspartate phosphatase
HHMJEDOE_00683 3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HHMJEDOE_00684 5.8e-77 yjoA S DinB family
HHMJEDOE_00685 3.7e-129 MA20_18170 S membrane transporter protein
HHMJEDOE_00686 7.1e-278 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HHMJEDOE_00687 9.6e-264 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HHMJEDOE_00688 3.5e-180 exuR K transcriptional
HHMJEDOE_00689 4.9e-219 exuT G Sugar (and other) transporter
HHMJEDOE_00690 5.8e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_00691 3.8e-204 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HHMJEDOE_00692 6.5e-182 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HHMJEDOE_00693 2.9e-174 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HHMJEDOE_00694 3e-246 yjmB G symporter YjmB
HHMJEDOE_00695 3.8e-273 uxaC 5.3.1.12 G glucuronate isomerase
HHMJEDOE_00696 1.1e-217 yjlD 1.6.99.3 C NADH dehydrogenase
HHMJEDOE_00697 5.9e-65 yjlC S Protein of unknown function (DUF1641)
HHMJEDOE_00698 5.6e-66 G Transmembrane secretion effector
HHMJEDOE_00699 1.7e-55 rrmJ 2.1.1.226, 2.1.1.227 J Methyltransferase
HHMJEDOE_00700 0.0 srfAB Q cog cog1020
HHMJEDOE_00701 0.0 srfAB Q Non-ribosomal peptide synthetase modules and related proteins
HHMJEDOE_00702 0.0 srfAB Q Non-ribosomal peptide synthetase modules and related proteins
HHMJEDOE_00703 3.2e-41 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHMJEDOE_00704 2.1e-74 yjlB S Cupin domain
HHMJEDOE_00705 7.1e-170 yjlA EG Putative multidrug resistance efflux transporter
HHMJEDOE_00706 7.5e-127 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HHMJEDOE_00707 3.4e-119 ybbM S transport system, permease component
HHMJEDOE_00708 4.9e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HHMJEDOE_00709 2.6e-28
HHMJEDOE_00710 5e-202 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHMJEDOE_00711 4.3e-217 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HHMJEDOE_00713 4.5e-101 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HHMJEDOE_00714 1.1e-06 S Domain of unknown function (DUF4352)
HHMJEDOE_00715 2.4e-93 yjgD S Protein of unknown function (DUF1641)
HHMJEDOE_00716 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HHMJEDOE_00717 1.3e-94 yjgB S Domain of unknown function (DUF4309)
HHMJEDOE_00718 7.8e-147 yjfC O Predicted Zn-dependent protease (DUF2268)
HHMJEDOE_00719 1.2e-19 yjfB S Putative motility protein
HHMJEDOE_00720 2.2e-79 S Protein of unknown function (DUF2690)
HHMJEDOE_00721 3.8e-249 xynD 3.5.1.104 G Polysaccharide deacetylase
HHMJEDOE_00723 1.4e-162 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HHMJEDOE_00724 2.3e-43 yjdJ S Domain of unknown function (DUF4306)
HHMJEDOE_00725 1.9e-26 S Domain of unknown function (DUF4177)
HHMJEDOE_00726 2.2e-71 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHMJEDOE_00728 5.2e-71 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HHMJEDOE_00729 9.5e-39 yjdF S Protein of unknown function (DUF2992)
HHMJEDOE_00731 3.7e-163 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHMJEDOE_00732 1.5e-307 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HHMJEDOE_00733 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HHMJEDOE_00734 3.3e-47 yjcN
HHMJEDOE_00736 5.7e-41 yjcS S Antibiotic biosynthesis monooxygenase
HHMJEDOE_00737 8.8e-167 S response regulator aspartate phosphatase
HHMJEDOE_00740 2.4e-204 yjcL S Protein of unknown function (DUF819)
HHMJEDOE_00741 3.9e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
HHMJEDOE_00742 1.7e-213 metC 2.5.1.48, 4.4.1.8 E cystathionine
HHMJEDOE_00743 1.8e-212 metB 2.5.1.48, 4.4.1.8 E cystathionine
HHMJEDOE_00744 2.7e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
HHMJEDOE_00745 1.6e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HHMJEDOE_00746 8.9e-69 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_00747 5.3e-46
HHMJEDOE_00748 7.1e-29
HHMJEDOE_00749 0.0 yjcD 3.6.4.12 L DNA helicase
HHMJEDOE_00750 1.4e-37 spoVIF S Stage VI sporulation protein F
HHMJEDOE_00753 2.4e-54 yjcA S Protein of unknown function (DUF1360)
HHMJEDOE_00754 6.3e-53 cotV S Spore Coat Protein X and V domain
HHMJEDOE_00755 7.9e-25 cotW
HHMJEDOE_00756 4e-71 cotX S Spore Coat Protein X and V domain
HHMJEDOE_00757 2.9e-95 cotY S Spore coat protein Z
HHMJEDOE_00758 2.5e-77 cotZ S Spore coat protein
HHMJEDOE_00759 1.6e-38 yjbX S Spore coat protein
HHMJEDOE_00760 3.6e-140 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HHMJEDOE_00761 2.8e-143 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHMJEDOE_00762 8.7e-179 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HHMJEDOE_00763 2.6e-127 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HHMJEDOE_00764 2.2e-28 thiS H thiamine diphosphate biosynthetic process
HHMJEDOE_00765 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
HHMJEDOE_00766 2.6e-101 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HHMJEDOE_00767 2.5e-132 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHMJEDOE_00768 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHMJEDOE_00769 2.9e-123 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HHMJEDOE_00770 1.2e-144 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHMJEDOE_00771 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHMJEDOE_00772 5.8e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HHMJEDOE_00773 4.3e-59 yjbL S Belongs to the UPF0738 family
HHMJEDOE_00774 1.1e-96 yjbK S protein conserved in bacteria
HHMJEDOE_00775 8.8e-96 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHMJEDOE_00776 4.1e-71 yjbI S Bacterial-like globin
HHMJEDOE_00777 1.3e-165 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HHMJEDOE_00778 7.5e-19
HHMJEDOE_00779 0.0 pepF E oligoendopeptidase F
HHMJEDOE_00780 7.1e-185 yjbF S Competence protein
HHMJEDOE_00781 2.9e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHMJEDOE_00782 6.2e-109 yjbE P Integral membrane protein TerC family
HHMJEDOE_00783 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHMJEDOE_00784 3.8e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_00785 3.1e-177 yjbB EGP Major Facilitator Superfamily
HHMJEDOE_00786 7.9e-171 oppF E Belongs to the ABC transporter superfamily
HHMJEDOE_00787 2.8e-196 oppD P Belongs to the ABC transporter superfamily
HHMJEDOE_00788 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00789 1e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00790 2.3e-311 oppA E ABC transporter substrate-binding protein
HHMJEDOE_00791 4.8e-182 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HHMJEDOE_00792 1.9e-146 yjbA S Belongs to the UPF0736 family
HHMJEDOE_00793 3.7e-160 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00794 8.8e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHMJEDOE_00795 4.8e-288 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HHMJEDOE_00796 1.8e-184 appF E Belongs to the ABC transporter superfamily
HHMJEDOE_00797 3.3e-183 appD P Belongs to the ABC transporter superfamily
HHMJEDOE_00798 2.2e-137 yjaZ O Zn-dependent protease
HHMJEDOE_00799 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHMJEDOE_00800 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHMJEDOE_00801 8.7e-23 yjzB
HHMJEDOE_00802 2.3e-24 comZ S ComZ
HHMJEDOE_00803 1.1e-178 med S Transcriptional activator protein med
HHMJEDOE_00804 3.4e-92 yjaV
HHMJEDOE_00805 1.9e-135 yjaU I carboxylic ester hydrolase activity
HHMJEDOE_00806 3e-16 yjzD S Protein of unknown function (DUF2929)
HHMJEDOE_00807 9.5e-28 yjzC S YjzC-like protein
HHMJEDOE_00808 1.6e-166 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHMJEDOE_00809 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HHMJEDOE_00810 8.5e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HHMJEDOE_00811 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HHMJEDOE_00812 5.2e-131 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HHMJEDOE_00813 4.1e-223 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HHMJEDOE_00814 4.3e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HHMJEDOE_00815 1.2e-89 norB G Major Facilitator Superfamily
HHMJEDOE_00816 7.8e-258 yitY C D-arabinono-1,4-lactone oxidase
HHMJEDOE_00817 9.7e-22 pilT S Proteolipid membrane potential modulator
HHMJEDOE_00818 8e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HHMJEDOE_00819 5.7e-138 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HHMJEDOE_00820 2.8e-151 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HHMJEDOE_00822 3.4e-26 S Protein of unknown function (DUF3813)
HHMJEDOE_00823 2.7e-71 ipi S Intracellular proteinase inhibitor
HHMJEDOE_00824 4.8e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HHMJEDOE_00825 7.7e-152 yitS S protein conserved in bacteria
HHMJEDOE_00826 4e-36 yitR S Domain of unknown function (DUF3784)
HHMJEDOE_00827 6.7e-156 cvfB S protein conserved in bacteria
HHMJEDOE_00828 3.3e-54 yajQ S Belongs to the UPF0234 family
HHMJEDOE_00829 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HHMJEDOE_00830 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
HHMJEDOE_00831 8.6e-127 yitH K Acetyltransferase (GNAT) domain
HHMJEDOE_00832 7.7e-225 yitG EGP Major facilitator Superfamily
HHMJEDOE_00833 2.7e-205 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HHMJEDOE_00834 5.5e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHMJEDOE_00835 1.7e-134 yitD 4.4.1.19 S synthase
HHMJEDOE_00836 7.6e-110 comB 3.1.3.71 H Belongs to the ComB family
HHMJEDOE_00837 5.6e-132 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HHMJEDOE_00838 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HHMJEDOE_00839 2.5e-104 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HHMJEDOE_00840 1e-145 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHMJEDOE_00841 7.8e-32 mcbG S Pentapeptide repeats (9 copies)
HHMJEDOE_00842 4.8e-255 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_00843 1.8e-94 argO S Lysine exporter protein LysE YggA
HHMJEDOE_00844 1e-82 yisT S DinB family
HHMJEDOE_00845 2.9e-190 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HHMJEDOE_00846 1.4e-85 J Acetyltransferase (GNAT) domain
HHMJEDOE_00847 1e-174 purR K helix_turn _helix lactose operon repressor
HHMJEDOE_00848 2.3e-159 yisR K Transcriptional regulator
HHMJEDOE_00849 8.3e-241 yisQ V Mate efflux family protein
HHMJEDOE_00850 4.9e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HHMJEDOE_00851 1.6e-85 yizA S Damage-inducible protein DinB
HHMJEDOE_00852 0.0 asnO 6.3.5.4 E Asparagine synthase
HHMJEDOE_00853 9.9e-92 yisN S Protein of unknown function (DUF2777)
HHMJEDOE_00854 0.0 wprA O Belongs to the peptidase S8 family
HHMJEDOE_00855 8.1e-55 yisL S UPF0344 protein
HHMJEDOE_00856 8.7e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HHMJEDOE_00857 1.2e-139 cotH M Spore Coat
HHMJEDOE_00858 3.6e-16 yisI S Spo0E like sporulation regulatory protein
HHMJEDOE_00859 1.9e-33 gerPA S Spore germination protein
HHMJEDOE_00860 1.7e-32 gerPB S cell differentiation
HHMJEDOE_00861 1.1e-51 gerPC S Spore germination protein
HHMJEDOE_00862 3.1e-23 gerPD S Spore germination protein
HHMJEDOE_00863 1.7e-61 gerPE S Spore germination protein GerPE
HHMJEDOE_00864 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HHMJEDOE_00865 1.3e-48 yisB V COG1403 Restriction endonuclease
HHMJEDOE_00866 0.0 sbcC L COG0419 ATPase involved in DNA repair
HHMJEDOE_00867 2.3e-215 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHMJEDOE_00868 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHMJEDOE_00869 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HHMJEDOE_00870 5.8e-71 yhjR S Rubrerythrin
HHMJEDOE_00871 4.2e-298 S Sugar transport-related sRNA regulator N-term
HHMJEDOE_00872 4.8e-192 EGP Transmembrane secretion effector
HHMJEDOE_00873 9.3e-193 abrB S membrane
HHMJEDOE_00874 2.4e-181 yhjM 5.1.1.1 K Transcriptional regulator
HHMJEDOE_00875 8.9e-240 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HHMJEDOE_00876 4.6e-157 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HHMJEDOE_00877 1.3e-190 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HHMJEDOE_00878 5.9e-206 glcP G Major Facilitator Superfamily
HHMJEDOE_00880 2e-89 yhjH K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_00881 6e-253 yhjG CH FAD binding domain
HHMJEDOE_00882 3.6e-88 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HHMJEDOE_00883 9.4e-107 yhjE S SNARE associated Golgi protein
HHMJEDOE_00884 1.5e-51 yhjD
HHMJEDOE_00885 2.6e-26 yhjC S Protein of unknown function (DUF3311)
HHMJEDOE_00886 2.3e-257 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHMJEDOE_00887 1.1e-40 yhjA S Excalibur calcium-binding domain
HHMJEDOE_00888 3.6e-160 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_00889 2.5e-106 comK K Competence transcription factor
HHMJEDOE_00890 8.3e-32 yhzC S IDEAL
HHMJEDOE_00891 3.1e-153 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_00892 1.3e-287 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HHMJEDOE_00893 1.4e-176 hemAT NT chemotaxis protein
HHMJEDOE_00894 1.3e-86 bioY S BioY family
HHMJEDOE_00895 2.3e-241 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HHMJEDOE_00896 1e-185 vraB 2.3.1.9 I Belongs to the thiolase family
HHMJEDOE_00897 3.7e-105 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HHMJEDOE_00898 2.3e-152 yfmC M Periplasmic binding protein
HHMJEDOE_00899 1.4e-176 yhfP 1.1.1.1 C Quinone oxidoreductase
HHMJEDOE_00900 4.4e-66 VY92_01935 K acetyltransferase
HHMJEDOE_00901 4.4e-195 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HHMJEDOE_00902 5.1e-232 yhfN 3.4.24.84 O Peptidase M48
HHMJEDOE_00903 3.1e-63 yhfM
HHMJEDOE_00904 6.6e-287 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HHMJEDOE_00905 9.7e-107 yhfK GM NmrA-like family
HHMJEDOE_00906 3.4e-183 lplJ 6.3.1.20 H Lipoate-protein ligase
HHMJEDOE_00907 9.3e-138 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HHMJEDOE_00908 1.4e-221 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHMJEDOE_00909 1.6e-67 3.4.13.21 S ASCH
HHMJEDOE_00910 2e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HHMJEDOE_00911 7.3e-125 yhfC S Putative membrane peptidase family (DUF2324)
HHMJEDOE_00912 4.1e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHMJEDOE_00913 1.1e-216 yhgE S YhgE Pip N-terminal domain protein
HHMJEDOE_00914 1.9e-98 yhgD K Transcriptional regulator
HHMJEDOE_00915 1.4e-262 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HHMJEDOE_00916 3.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HHMJEDOE_00917 1.1e-197 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HHMJEDOE_00918 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHMJEDOE_00919 3.3e-86 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HHMJEDOE_00920 1.2e-33 1.15.1.2 C Rubrerythrin
HHMJEDOE_00921 4.5e-234 yhfA C membrane
HHMJEDOE_00922 3e-218 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HHMJEDOE_00923 4.1e-106 ecsC S EcsC protein family
HHMJEDOE_00924 2.7e-198 ecsB U ABC transporter
HHMJEDOE_00925 3.3e-135 ecsA V transporter (ATP-binding protein)
HHMJEDOE_00926 5.2e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HHMJEDOE_00927 3.1e-198 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HHMJEDOE_00928 8.4e-77 trpP S Tryptophan transporter TrpP
HHMJEDOE_00929 5.6e-20
HHMJEDOE_00930 3.8e-36 yhaH S YtxH-like protein
HHMJEDOE_00931 2.9e-113 hpr K Negative regulator of protease production and sporulation
HHMJEDOE_00932 3e-51 yhaI S Protein of unknown function (DUF1878)
HHMJEDOE_00933 2.1e-88 yhaK S Putative zincin peptidase
HHMJEDOE_00934 6.8e-111 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHMJEDOE_00935 5.6e-19 yhaL S Sporulation protein YhaL
HHMJEDOE_00936 1e-176 yhaM L Shows a 3'-5' exoribonuclease activity
HHMJEDOE_00937 0.0 yhaN L AAA domain
HHMJEDOE_00938 5.9e-214 yhaO L DNA repair exonuclease
HHMJEDOE_00939 1.4e-200 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HHMJEDOE_00940 8.6e-162 yhaQ S ABC transporter, ATP-binding protein
HHMJEDOE_00941 4.3e-23 S YhzD-like protein
HHMJEDOE_00942 6.5e-126 yhaR 5.3.3.18 I enoyl-CoA hydratase
HHMJEDOE_00944 2.1e-85 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HHMJEDOE_00945 1e-205 yhaU P COG0475 Kef-type K transport systems, membrane components
HHMJEDOE_00946 6.7e-284 hemZ H coproporphyrinogen III oxidase
HHMJEDOE_00947 2.6e-155 yhaX S haloacid dehalogenase-like hydrolase
HHMJEDOE_00948 8.7e-183 yhaZ L DNA alkylation repair enzyme
HHMJEDOE_00949 1.2e-47 yheA S Belongs to the UPF0342 family
HHMJEDOE_00950 3.8e-191 yheB S Belongs to the UPF0754 family
HHMJEDOE_00951 7.1e-211 yheC HJ YheC/D like ATP-grasp
HHMJEDOE_00952 1.7e-254 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HHMJEDOE_00953 7.2e-35 yheE S Family of unknown function (DUF5342)
HHMJEDOE_00954 2.4e-27 sspB S spore protein
HHMJEDOE_00956 1.1e-96 yheG GM NAD(P)H-binding
HHMJEDOE_00957 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHMJEDOE_00958 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHMJEDOE_00959 3.4e-83 nhaX T Belongs to the universal stress protein A family
HHMJEDOE_00960 1.8e-219 nhaC C Na H antiporter
HHMJEDOE_00961 6.7e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HHMJEDOE_00962 4.6e-133 yheN G deacetylase
HHMJEDOE_00963 9.4e-130 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HHMJEDOE_00964 1.4e-198 yhdY M Mechanosensitive ion channel
HHMJEDOE_00966 1.2e-126 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHMJEDOE_00967 1.4e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHMJEDOE_00968 2.2e-39 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHMJEDOE_00969 8.4e-233 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HHMJEDOE_00970 1.8e-215 yhdR 2.6.1.1 E Aminotransferase
HHMJEDOE_00971 8.9e-69 cueR K transcriptional
HHMJEDOE_00972 1.4e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HHMJEDOE_00973 1.1e-164 galE 5.1.3.2 GM GDP-mannose 4,6 dehydratase
HHMJEDOE_00974 3.3e-171 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HHMJEDOE_00975 1.5e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HHMJEDOE_00976 2.7e-180 yhdN C Aldo keto reductase
HHMJEDOE_00977 1.2e-85 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_00978 2.1e-194 yhdL S Sigma factor regulator N-terminal
HHMJEDOE_00979 8.1e-45 yhdK S Sigma-M inhibitor protein
HHMJEDOE_00980 7e-69 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_00981 1.6e-231 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_00982 3.3e-234 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHMJEDOE_00983 2.7e-247 yhdG E amino acid
HHMJEDOE_00984 4.9e-154 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_00985 4.4e-200 citA 2.3.3.1 C Belongs to the citrate synthase family
HHMJEDOE_00986 1.7e-159 citR K Transcriptional regulator
HHMJEDOE_00987 1.5e-135 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHMJEDOE_00988 1e-246 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HHMJEDOE_00989 1.1e-272 ycgB S Stage V sporulation protein R
HHMJEDOE_00990 1.9e-230 ygxB M Conserved TM helix
HHMJEDOE_00991 1.1e-74 nsrR K Transcriptional regulator
HHMJEDOE_00992 2.5e-171 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHMJEDOE_00993 2.1e-49 yhdC S Protein of unknown function (DUF3889)
HHMJEDOE_00994 2.8e-38 yhdB S YhdB-like protein
HHMJEDOE_00995 6.3e-80 azr 1.7.1.6 S NADPH-dependent FMN reductase
HHMJEDOE_00996 1.6e-104 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_00997 5.6e-198 yhcY 2.7.13.3 T Histidine kinase
HHMJEDOE_00998 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HHMJEDOE_00999 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HHMJEDOE_01000 2e-288 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHMJEDOE_01001 4.8e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HHMJEDOE_01002 2.6e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HHMJEDOE_01003 5.2e-256 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHMJEDOE_01004 2.2e-82 mepB S MepB protein
HHMJEDOE_01005 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HHMJEDOE_01006 2.5e-118 yhcW 5.4.2.6 S hydrolase
HHMJEDOE_01007 1.4e-66 yhcV S COG0517 FOG CBS domain
HHMJEDOE_01008 3.6e-64 yhcU S Family of unknown function (DUF5365)
HHMJEDOE_01009 1.1e-159 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHMJEDOE_01010 3.4e-98 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HHMJEDOE_01011 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HHMJEDOE_01012 3.2e-97 yhcQ M Spore coat protein
HHMJEDOE_01013 1.9e-151 yhcP
HHMJEDOE_01014 4.6e-63 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHMJEDOE_01015 5.6e-37 yhcM
HHMJEDOE_01016 1.1e-211 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHMJEDOE_01017 4.5e-181 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HHMJEDOE_01018 3.3e-139 metQ M Belongs to the nlpA lipoprotein family
HHMJEDOE_01019 1e-30 cspB K Cold-shock protein
HHMJEDOE_01020 4.8e-155 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHMJEDOE_01021 6.5e-157 yhcH V ABC transporter, ATP-binding protein
HHMJEDOE_01022 3e-114 yhcG V ABC transporter, ATP-binding protein
HHMJEDOE_01023 3.3e-59 yhcF K Transcriptional regulator
HHMJEDOE_01024 1.9e-53
HHMJEDOE_01025 1.6e-32 yhcC
HHMJEDOE_01026 2.8e-96 yhcB 1.6.5.2 S Belongs to the WrbA family
HHMJEDOE_01027 3e-282 yhcA EGP Major facilitator Superfamily
HHMJEDOE_01028 4.7e-90 yhbJ V COG1566 Multidrug resistance efflux pump
HHMJEDOE_01029 1e-73 yhbI K DNA-binding transcription factor activity
HHMJEDOE_01030 7.9e-224 yhbH S Belongs to the UPF0229 family
HHMJEDOE_01031 0.0 prkA T Ser protein kinase
HHMJEDOE_01032 1.6e-57 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HHMJEDOE_01033 9.8e-60 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HHMJEDOE_01034 1.1e-117 yhbD K Protein of unknown function (DUF4004)
HHMJEDOE_01035 5.9e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHMJEDOE_01036 1.2e-166 yhbB S Putative amidase domain
HHMJEDOE_01037 2.5e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HHMJEDOE_01038 2.1e-106 yhzB S B3/4 domain
HHMJEDOE_01040 4.4e-29 K Transcriptional regulator
HHMJEDOE_01041 3e-73 ygaO
HHMJEDOE_01042 6.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHMJEDOE_01045 6.7e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HHMJEDOE_01046 2.5e-139 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHMJEDOE_01047 1.1e-162 ssuA M Sulfonate ABC transporter
HHMJEDOE_01048 3.2e-133 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HHMJEDOE_01049 3.6e-287 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HHMJEDOE_01051 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HHMJEDOE_01052 1.2e-34 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HHMJEDOE_01054 1.7e-25
HHMJEDOE_01055 4.4e-138 spo0M S COG4326 Sporulation control protein
HHMJEDOE_01059 2e-08
HHMJEDOE_01067 7.8e-08
HHMJEDOE_01072 1.2e-186 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HHMJEDOE_01073 1.1e-141 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HHMJEDOE_01075 3.7e-117 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HHMJEDOE_01076 2.4e-119 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HHMJEDOE_01077 3.2e-168 spoIID D Stage II sporulation protein D
HHMJEDOE_01078 2.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHMJEDOE_01079 1.6e-129 ywmB S TATA-box binding
HHMJEDOE_01080 1.3e-32 ywzB S membrane
HHMJEDOE_01081 7.2e-83 ywmA
HHMJEDOE_01082 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHMJEDOE_01083 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHMJEDOE_01084 9.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHMJEDOE_01085 5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHMJEDOE_01086 3.4e-84 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHMJEDOE_01087 2.1e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHMJEDOE_01088 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHMJEDOE_01089 6.6e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HHMJEDOE_01090 3.7e-61 atpI S ATP synthase
HHMJEDOE_01091 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHMJEDOE_01092 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHMJEDOE_01093 2.6e-89 ywlG S Belongs to the UPF0340 family
HHMJEDOE_01094 2.2e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HHMJEDOE_01095 2e-74 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHMJEDOE_01096 2.1e-89 mntP P Probably functions as a manganese efflux pump
HHMJEDOE_01097 4.7e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHMJEDOE_01098 1.6e-71 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HHMJEDOE_01099 1.3e-106 spoIIR S stage II sporulation protein R
HHMJEDOE_01100 5.9e-53 ywlA S Uncharacterised protein family (UPF0715)
HHMJEDOE_01102 4.6e-152 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHMJEDOE_01103 1.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHMJEDOE_01104 1.2e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHMJEDOE_01105 4e-85 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HHMJEDOE_01106 8e-158 ywkB S Membrane transport protein
HHMJEDOE_01107 0.0 sfcA 1.1.1.38 C malic enzyme
HHMJEDOE_01108 5.5e-101 tdk 2.7.1.21 F thymidine kinase
HHMJEDOE_01109 1.1e-32 rpmE J Binds the 23S rRNA
HHMJEDOE_01110 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HHMJEDOE_01111 8.9e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HHMJEDOE_01112 4.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHMJEDOE_01113 3.8e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HHMJEDOE_01114 1.4e-156 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HHMJEDOE_01115 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HHMJEDOE_01116 1.1e-89 ywjG S Domain of unknown function (DUF2529)
HHMJEDOE_01117 2e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHMJEDOE_01118 2.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHMJEDOE_01119 3.1e-201 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HHMJEDOE_01120 0.0 fadF C COG0247 Fe-S oxidoreductase
HHMJEDOE_01121 3.5e-203 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HHMJEDOE_01122 3.9e-176 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HHMJEDOE_01123 1.8e-41 ywjC
HHMJEDOE_01124 6.9e-87 ywjB H RibD C-terminal domain
HHMJEDOE_01125 0.0 ywjA V ABC transporter
HHMJEDOE_01126 3.5e-277 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHMJEDOE_01127 3e-97 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHMJEDOE_01128 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
HHMJEDOE_01129 1.3e-88 narJ 1.7.5.1 C nitrate reductase
HHMJEDOE_01130 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
HHMJEDOE_01131 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHMJEDOE_01132 8.8e-81 arfM T cyclic nucleotide binding
HHMJEDOE_01133 1.5e-129 ywiC S YwiC-like protein
HHMJEDOE_01134 2.1e-126 fnr K helix_turn_helix, cAMP Regulatory protein
HHMJEDOE_01135 7.8e-211 narK P COG2223 Nitrate nitrite transporter
HHMJEDOE_01136 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHMJEDOE_01137 2e-71 ywiB S protein conserved in bacteria
HHMJEDOE_01138 1e-07 S Bacteriocin subtilosin A
HHMJEDOE_01139 8.7e-267 C Fe-S oxidoreductases
HHMJEDOE_01141 2.7e-126 cbiO V ABC transporter
HHMJEDOE_01142 2.7e-225 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HHMJEDOE_01143 3.3e-193 2.7.1.26, 2.7.7.2 L Peptidase, M16
HHMJEDOE_01144 1.9e-218 L Peptidase, M16
HHMJEDOE_01146 9.3e-200 ywhL CO amine dehydrogenase activity
HHMJEDOE_01147 1.1e-184 ywhK CO amine dehydrogenase activity
HHMJEDOE_01148 1.7e-85 S aspartate phosphatase
HHMJEDOE_01150 1.1e-166 speB 3.5.3.11 E Belongs to the arginase family
HHMJEDOE_01151 5.3e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HHMJEDOE_01152 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHMJEDOE_01153 3e-64
HHMJEDOE_01154 4.9e-93 ywhD S YwhD family
HHMJEDOE_01155 8.1e-117 ywhC S Peptidase family M50
HHMJEDOE_01156 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HHMJEDOE_01157 8.9e-69 ywhA K Transcriptional regulator
HHMJEDOE_01158 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHMJEDOE_01159 2.1e-223 mmr U Major Facilitator Superfamily
HHMJEDOE_01160 4.7e-74 yffB K Transcriptional regulator
HHMJEDOE_01161 1.3e-87 ywgA 2.1.1.72, 3.1.21.3
HHMJEDOE_01162 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
HHMJEDOE_01163 3.1e-36 ywzC S Belongs to the UPF0741 family
HHMJEDOE_01164 3.8e-105 rsfA_1
HHMJEDOE_01165 1.4e-148 ywfM EG EamA-like transporter family
HHMJEDOE_01166 3.8e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HHMJEDOE_01167 1.2e-152 cysL K Transcriptional regulator
HHMJEDOE_01168 2.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HHMJEDOE_01169 4.3e-146 ywfI C May function as heme-dependent peroxidase
HHMJEDOE_01170 6.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_01171 4e-223 ywfG 2.6.1.83 E Aminotransferase class I and II
HHMJEDOE_01172 1.1e-204 bacE EGP Major facilitator Superfamily
HHMJEDOE_01173 1.2e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HHMJEDOE_01174 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_01175 1.2e-134 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HHMJEDOE_01176 4.1e-107 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HHMJEDOE_01177 6e-190 ywfA EGP Major facilitator Superfamily
HHMJEDOE_01178 4.4e-291 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHMJEDOE_01179 7.7e-241 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHMJEDOE_01180 2.4e-75
HHMJEDOE_01181 1.3e-84 spsL 5.1.3.13 M Spore Coat
HHMJEDOE_01182 3.2e-150 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HHMJEDOE_01183 4.5e-177 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHMJEDOE_01184 7.4e-135 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HHMJEDOE_01185 2.1e-164 spsG M Spore Coat
HHMJEDOE_01186 2.9e-120 spsF M Spore Coat
HHMJEDOE_01187 1.1e-206 spsE 2.5.1.56 M acid synthase
HHMJEDOE_01188 2e-155 spsD 2.3.1.210 K Spore Coat
HHMJEDOE_01189 7.9e-216 spsC E Belongs to the DegT DnrJ EryC1 family
HHMJEDOE_01190 5.4e-259 spsB M Capsule polysaccharide biosynthesis protein
HHMJEDOE_01191 3.6e-140 spsA M Spore Coat
HHMJEDOE_01192 3.5e-70 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HHMJEDOE_01193 9.7e-59 ywdK S small membrane protein
HHMJEDOE_01194 5.8e-231 ywdJ F Xanthine uracil
HHMJEDOE_01195 1.4e-45 ywdI S Family of unknown function (DUF5327)
HHMJEDOE_01196 6.3e-257 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HHMJEDOE_01197 3e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHMJEDOE_01198 3.4e-149 ywdF GT2,GT4 S Glycosyltransferase like family 2
HHMJEDOE_01199 8.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHMJEDOE_01200 1.4e-75 ctsR K Belongs to the CtsR family
HHMJEDOE_01201 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HHMJEDOE_01202 4.8e-199 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HHMJEDOE_01203 0.0 clpC O Belongs to the ClpA ClpB family
HHMJEDOE_01204 4e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHMJEDOE_01205 1.4e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HHMJEDOE_01206 7.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HHMJEDOE_01207 2.2e-120 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HHMJEDOE_01208 5.9e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HHMJEDOE_01209 4.5e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHMJEDOE_01210 2.1e-117 cysE 2.3.1.30 E Serine acetyltransferase
HHMJEDOE_01211 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHMJEDOE_01212 2.6e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHMJEDOE_01213 8.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHMJEDOE_01214 4.7e-88 yacP S RNA-binding protein containing a PIN domain
HHMJEDOE_01215 4.4e-115 sigH K Belongs to the sigma-70 factor family
HHMJEDOE_01216 5.2e-18 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHMJEDOE_01217 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
HHMJEDOE_01218 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHMJEDOE_01219 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHMJEDOE_01220 1.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHMJEDOE_01221 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHMJEDOE_01222 2.2e-105 rsmC 2.1.1.172 J Methyltransferase
HHMJEDOE_01223 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHMJEDOE_01224 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHMJEDOE_01225 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HHMJEDOE_01226 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHMJEDOE_01227 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHMJEDOE_01228 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHMJEDOE_01229 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHMJEDOE_01230 6.8e-157 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HHMJEDOE_01231 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HHMJEDOE_01232 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHMJEDOE_01233 3e-105 rplD J Forms part of the polypeptide exit tunnel
HHMJEDOE_01234 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHMJEDOE_01235 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHMJEDOE_01236 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHMJEDOE_01237 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHMJEDOE_01238 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHMJEDOE_01239 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHMJEDOE_01240 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HHMJEDOE_01241 4.6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHMJEDOE_01242 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHMJEDOE_01243 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHMJEDOE_01244 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHMJEDOE_01245 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHMJEDOE_01246 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHMJEDOE_01247 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHMJEDOE_01248 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHMJEDOE_01249 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHMJEDOE_01250 1.9e-23 rpmD J Ribosomal protein L30
HHMJEDOE_01251 6.9e-72 rplO J binds to the 23S rRNA
HHMJEDOE_01252 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHMJEDOE_01253 2.2e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHMJEDOE_01254 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HHMJEDOE_01255 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHMJEDOE_01256 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HHMJEDOE_01257 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHMJEDOE_01258 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHMJEDOE_01259 9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHMJEDOE_01260 3.6e-58 rplQ J Ribosomal protein L17
HHMJEDOE_01261 6.2e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHMJEDOE_01262 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHMJEDOE_01263 1.6e-122 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHMJEDOE_01264 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHMJEDOE_01265 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHMJEDOE_01266 8.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HHMJEDOE_01267 1.8e-136 ybaJ Q Methyltransferase domain
HHMJEDOE_01268 2.8e-65 ybaK S Protein of unknown function (DUF2521)
HHMJEDOE_01269 2.1e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHMJEDOE_01270 1.1e-195 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HHMJEDOE_01271 7.6e-84 gerD
HHMJEDOE_01272 1.4e-99 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HHMJEDOE_01273 2.8e-137 pdaB 3.5.1.104 G Polysaccharide deacetylase
HHMJEDOE_01274 2e-08
HHMJEDOE_01279 8.4e-30 csfB S Inhibitor of sigma-G Gin
HHMJEDOE_01280 1.5e-96 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HHMJEDOE_01281 8.7e-191 yaaN P Belongs to the TelA family
HHMJEDOE_01282 2e-253 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HHMJEDOE_01283 2.5e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHMJEDOE_01284 8.3e-54 yaaQ S protein conserved in bacteria
HHMJEDOE_01285 1.4e-69 yaaR S protein conserved in bacteria
HHMJEDOE_01286 2.5e-175 holB 2.7.7.7 L DNA polymerase III
HHMJEDOE_01287 1.7e-143 yaaT S stage 0 sporulation protein
HHMJEDOE_01288 4.8e-31 yabA L Involved in initiation control of chromosome replication
HHMJEDOE_01289 4.4e-135 yabB 2.1.1.223 S Conserved hypothetical protein 95
HHMJEDOE_01290 3.1e-47 yazA L endonuclease containing a URI domain
HHMJEDOE_01291 5.1e-143 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHMJEDOE_01292 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HHMJEDOE_01293 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHMJEDOE_01294 2.5e-141 tatD L hydrolase, TatD
HHMJEDOE_01295 7.8e-180 rpfB GH23 T protein conserved in bacteria
HHMJEDOE_01296 5.7e-95 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHMJEDOE_01297 1.6e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHMJEDOE_01298 5.2e-135 yabG S peptidase
HHMJEDOE_01299 7.8e-39 veg S protein conserved in bacteria
HHMJEDOE_01300 1.9e-26 sspF S DNA topological change
HHMJEDOE_01301 2.8e-157 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHMJEDOE_01302 5e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HHMJEDOE_01303 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HHMJEDOE_01304 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HHMJEDOE_01305 8.4e-10 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HHMJEDOE_01306 2.6e-226 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHMJEDOE_01307 1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHMJEDOE_01308 3.4e-93 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HHMJEDOE_01309 1.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHMJEDOE_01310 5.8e-38 yabK S Peptide ABC transporter permease
HHMJEDOE_01311 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHMJEDOE_01312 1.5e-92 spoVT K stage V sporulation protein
HHMJEDOE_01313 2.5e-265 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_01314 7.3e-235 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HHMJEDOE_01315 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HHMJEDOE_01316 1.5e-49 yabP S Sporulation protein YabP
HHMJEDOE_01317 2.2e-103 yabQ S spore cortex biosynthesis protein
HHMJEDOE_01318 1.1e-44 divIC D Septum formation initiator
HHMJEDOE_01319 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HHMJEDOE_01322 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HHMJEDOE_01323 4.9e-123 yabS S protein containing a von Willebrand factor type A (vWA) domain
HHMJEDOE_01324 8.2e-177 KLT serine threonine protein kinase
HHMJEDOE_01325 9.4e-264 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHMJEDOE_01326 6.7e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHMJEDOE_01327 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHMJEDOE_01328 4.4e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HHMJEDOE_01329 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHMJEDOE_01330 2.7e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HHMJEDOE_01331 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHMJEDOE_01332 3.8e-257 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHMJEDOE_01333 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HHMJEDOE_01334 7.7e-155 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HHMJEDOE_01335 1e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HHMJEDOE_01336 1e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HHMJEDOE_01337 2.2e-82 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HHMJEDOE_01338 1.5e-29 yazB K transcriptional
HHMJEDOE_01339 6.2e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHMJEDOE_01340 4.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHMJEDOE_01341 7.8e-08
HHMJEDOE_01343 4.6e-161 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HHMJEDOE_01344 1.1e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HHMJEDOE_01345 2.2e-117 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HHMJEDOE_01346 7.6e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HHMJEDOE_01347 7.6e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHMJEDOE_01348 3.2e-307 ydiF S ABC transporter
HHMJEDOE_01349 1.6e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HHMJEDOE_01350 1.1e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHMJEDOE_01351 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHMJEDOE_01352 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHMJEDOE_01353 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HHMJEDOE_01354 3.2e-122 ydiL S CAAX protease self-immunity
HHMJEDOE_01355 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHMJEDOE_01356 1.6e-278 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHMJEDOE_01358 1.1e-40
HHMJEDOE_01359 2e-237 yobL S Bacterial EndoU nuclease
HHMJEDOE_01360 2.2e-78 3.1.21.3 V Type I restriction modification DNA specificity domain
HHMJEDOE_01361 1.2e-288 hsdM 2.1.1.72 V Type I restriction-modification system
HHMJEDOE_01362 4.8e-91 3.1.21.3 V Type I restriction modification DNA specificity domain
HHMJEDOE_01363 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HHMJEDOE_01364 0.0 K NB-ARC domain
HHMJEDOE_01365 1e-198 gutB 1.1.1.14 E Dehydrogenase
HHMJEDOE_01366 2e-242 gutA G MFS/sugar transport protein
HHMJEDOE_01367 4.4e-164 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HHMJEDOE_01368 1.7e-101 pspA KT Phage shock protein A
HHMJEDOE_01369 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHMJEDOE_01370 1.4e-123 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HHMJEDOE_01371 4.5e-140 ydjI S virion core protein (lumpy skin disease virus)
HHMJEDOE_01372 4.8e-177 S Ion transport 2 domain protein
HHMJEDOE_01373 1.6e-250 iolT EGP Major facilitator Superfamily
HHMJEDOE_01374 1.4e-192 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HHMJEDOE_01375 8.4e-63 ydjM M Lytic transglycolase
HHMJEDOE_01376 3.7e-140 ydjN U Involved in the tonB-independent uptake of proteins
HHMJEDOE_01377 2.6e-144 yclE 3.4.11.5 S Alpha beta hydrolase
HHMJEDOE_01378 5.4e-75 yclD
HHMJEDOE_01379 4.4e-38 bsdD 4.1.1.61 S response to toxic substance
HHMJEDOE_01380 5e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HHMJEDOE_01381 3e-99 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHMJEDOE_01382 2.5e-158 bsdA K LysR substrate binding domain
HHMJEDOE_01383 6e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HHMJEDOE_01384 3.4e-121 tcyB P COG0765 ABC-type amino acid transport system, permease component
HHMJEDOE_01385 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHMJEDOE_01386 3.8e-111 yczE S membrane
HHMJEDOE_01387 7.7e-115 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HHMJEDOE_01388 4e-240 ycxD K GntR family transcriptional regulator
HHMJEDOE_01389 2e-145 ycxC EG EamA-like transporter family
HHMJEDOE_01390 5.6e-212 EGP Major Facilitator Superfamily
HHMJEDOE_01391 8.9e-133 srfAD Q thioesterase
HHMJEDOE_01392 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HHMJEDOE_01393 2e-231 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01394 3.7e-163 yaaC S YaaC-like Protein
HHMJEDOE_01395 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HHMJEDOE_01396 3.5e-244 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHMJEDOE_01397 9.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HHMJEDOE_01398 2.9e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HHMJEDOE_01399 6.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHMJEDOE_01400 1.3e-09
HHMJEDOE_01401 1.1e-118 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HHMJEDOE_01402 3.3e-112 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HHMJEDOE_01403 2.3e-208 yaaH M Glycoside Hydrolase Family
HHMJEDOE_01404 3.3e-92 yaaI Q COG1335 Amidases related to nicotinamidase
HHMJEDOE_01405 9.9e-80 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHMJEDOE_01406 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHMJEDOE_01407 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHMJEDOE_01408 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHMJEDOE_01409 2.3e-31 yaaL S Protein of unknown function (DUF2508)
HHMJEDOE_01410 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HHMJEDOE_01411 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01412 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01413 9.4e-242 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01414 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01415 0.0 vpr O Belongs to the peptidase S8 family
HHMJEDOE_01417 2.7e-149 sacT K transcriptional antiterminator
HHMJEDOE_01418 9.4e-133 focA P Formate/nitrite transporter
HHMJEDOE_01419 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_01420 5.8e-277 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HHMJEDOE_01422 4.1e-29 ywdA
HHMJEDOE_01423 4.7e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_01424 2.1e-245 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HHMJEDOE_01425 1.5e-175 yoxA 5.1.3.3 G Aldose 1-epimerase
HHMJEDOE_01426 6e-239 yoeA V MATE efflux family protein
HHMJEDOE_01427 2.2e-96 yoeB S IseA DL-endopeptidase inhibitor
HHMJEDOE_01429 9.4e-95 L Integrase
HHMJEDOE_01430 1.5e-33 yoeD G Helix-turn-helix domain
HHMJEDOE_01431 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HHMJEDOE_01432 4.4e-139 gltR1 K Transcriptional regulator
HHMJEDOE_01433 1.6e-169 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HHMJEDOE_01434 1.8e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HHMJEDOE_01435 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HHMJEDOE_01436 8.1e-152 gltC K Transcriptional regulator
HHMJEDOE_01437 9e-193 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HHMJEDOE_01438 6.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHMJEDOE_01439 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HHMJEDOE_01440 3.8e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_01441 1.1e-36 yoxC S Bacterial protein of unknown function (DUF948)
HHMJEDOE_01442 7.7e-38 yoxB
HHMJEDOE_01443 1e-62 yoxB
HHMJEDOE_01444 6.4e-38 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHMJEDOE_01445 2.6e-127 V ABC-2 family transporter protein
HHMJEDOE_01446 1.4e-93 V ABC-2 type transporter
HHMJEDOE_01447 1.1e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
HHMJEDOE_01448 1.9e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_01449 2.7e-230 yoaB EGP Major facilitator Superfamily
HHMJEDOE_01450 5.4e-254 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HHMJEDOE_01451 1.8e-176 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHMJEDOE_01452 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHMJEDOE_01453 6.3e-37 yoaF
HHMJEDOE_01454 1.7e-50 S Oxidoreductase family, C-terminal alpha/beta domain
HHMJEDOE_01455 4.8e-16 purR K Transcriptional regulator
HHMJEDOE_01456 1.4e-07 ywlA S Uncharacterised protein family (UPF0715)
HHMJEDOE_01457 1e-12
HHMJEDOE_01458 3.3e-38 S Protein of unknown function (DUF4025)
HHMJEDOE_01459 1e-163 mcpU NT methyl-accepting chemotaxis protein
HHMJEDOE_01460 1.4e-254 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HHMJEDOE_01461 1.6e-123 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HHMJEDOE_01463 2.7e-103 yoaK S Membrane
HHMJEDOE_01464 8.6e-190 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HHMJEDOE_01465 5.4e-128 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_01466 9.8e-47 yoaW
HHMJEDOE_01467 3.3e-121 yoqW S Belongs to the SOS response-associated peptidase family
HHMJEDOE_01470 7.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HHMJEDOE_01472 1.8e-57 yoaQ S Evidence 4 Homologs of previously reported genes of
HHMJEDOE_01474 2.3e-66
HHMJEDOE_01475 3.7e-152 yoaR V vancomycin resistance protein
HHMJEDOE_01476 3.6e-66 yoaS S Protein of unknown function (DUF2975)
HHMJEDOE_01477 1.3e-29 yozG K Transcriptional regulator
HHMJEDOE_01478 9.1e-139 yoaT S Protein of unknown function (DUF817)
HHMJEDOE_01479 1.4e-148 yoaU K LysR substrate binding domain
HHMJEDOE_01480 3.4e-155 yijE EG EamA-like transporter family
HHMJEDOE_01482 6.3e-72 S CAAX protease self-immunity
HHMJEDOE_01483 1.7e-103 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HHMJEDOE_01484 6.6e-183 S aspartate phosphatase
HHMJEDOE_01486 3.6e-55 S Uncharacterized protein conserved in bacteria (DUF2200)
HHMJEDOE_01487 8.1e-247 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HHMJEDOE_01488 2.4e-176 adhP 1.1.1.1 C alcohol dehydrogenase
HHMJEDOE_01489 1.6e-109 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HHMJEDOE_01490 1.2e-32 S DNA ligase (ATP) activity
HHMJEDOE_01491 1.2e-08
HHMJEDOE_01492 1.9e-08 S Hypothetical protein (DUF2513)
HHMJEDOE_01493 4.8e-38 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HHMJEDOE_01496 5.7e-29
HHMJEDOE_01498 3.8e-90 S aspartate phosphatase
HHMJEDOE_01500 3.4e-18
HHMJEDOE_01501 4.7e-29 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHMJEDOE_01502 6.4e-176 S impB/mucB/samB family C-terminal domain
HHMJEDOE_01503 1.6e-52 S YolD-like protein
HHMJEDOE_01505 9e-106 yobJ
HHMJEDOE_01506 7.4e-85 S SMI1-KNR4 cell-wall
HHMJEDOE_01507 3e-291 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HHMJEDOE_01508 1.9e-50 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HHMJEDOE_01509 1.7e-131 yobQ K helix_turn_helix, arabinose operon control protein
HHMJEDOE_01510 3.5e-124 yobR 2.3.1.1 J FR47-like protein
HHMJEDOE_01511 2.7e-84 yobS K Transcriptional regulator
HHMJEDOE_01512 2.3e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HHMJEDOE_01513 1.3e-76 yobU K Bacterial transcription activator, effector binding domain
HHMJEDOE_01514 8.4e-160 yobV K WYL domain
HHMJEDOE_01515 4e-85 yobW
HHMJEDOE_01516 1.2e-49 czrA K transcriptional
HHMJEDOE_01517 7.8e-115 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HHMJEDOE_01518 7.3e-92 yozB S membrane
HHMJEDOE_01519 2.8e-132
HHMJEDOE_01520 3.7e-90 yocC
HHMJEDOE_01521 7.6e-180 yocD 3.4.17.13 V peptidase S66
HHMJEDOE_01522 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HHMJEDOE_01523 4.9e-191 desK 2.7.13.3 T Histidine kinase
HHMJEDOE_01524 1.9e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_01525 3.6e-109 yocH CBM50 M COG1388 FOG LysM repeat
HHMJEDOE_01526 0.0 recQ 3.6.4.12 L DNA helicase
HHMJEDOE_01527 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHMJEDOE_01528 1.5e-78 dksA T general stress protein
HHMJEDOE_01529 1.6e-55 yozO S Bacterial PH domain
HHMJEDOE_01530 8e-31 yozC
HHMJEDOE_01531 1.2e-285 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HHMJEDOE_01532 4.1e-276 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HHMJEDOE_01533 2.9e-159 sodA 1.15.1.1 P Superoxide dismutase
HHMJEDOE_01534 1.4e-224 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HHMJEDOE_01535 4.6e-161 yocS S -transporter
HHMJEDOE_01536 2e-177 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HHMJEDOE_01537 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HHMJEDOE_01538 0.0 yojO P Von Willebrand factor
HHMJEDOE_01539 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
HHMJEDOE_01540 2e-103 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HHMJEDOE_01541 5.3e-186 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HHMJEDOE_01542 1.3e-216 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HHMJEDOE_01543 9.2e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHMJEDOE_01545 2.8e-233 norM V Multidrug efflux pump
HHMJEDOE_01546 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHMJEDOE_01547 4.5e-123 yojG S deacetylase
HHMJEDOE_01548 6.3e-60 yojF S Protein of unknown function (DUF1806)
HHMJEDOE_01549 4.4e-40
HHMJEDOE_01550 1.1e-153 rarD S -transporter
HHMJEDOE_01551 1.7e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
HHMJEDOE_01552 2.2e-08
HHMJEDOE_01553 2.7e-56 gntP EG COG2610 H gluconate symporter and related permeases
HHMJEDOE_01554 1.8e-128 gntP EG COG2610 H gluconate symporter and related permeases
HHMJEDOE_01555 2.8e-61 yodA S tautomerase
HHMJEDOE_01556 7e-53 yodB K transcriptional
HHMJEDOE_01557 2e-106 yodC C nitroreductase
HHMJEDOE_01558 5.9e-106 mhqD S Carboxylesterase
HHMJEDOE_01559 3e-162 yodE E COG0346 Lactoylglutathione lyase and related lyases
HHMJEDOE_01560 1.2e-26 S Protein of unknown function (DUF3311)
HHMJEDOE_01561 3.4e-264 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHMJEDOE_01562 6.7e-246 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HHMJEDOE_01563 3.1e-122 yodH Q Methyltransferase
HHMJEDOE_01564 1.7e-22 yodI
HHMJEDOE_01565 2.5e-131 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HHMJEDOE_01566 1.6e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HHMJEDOE_01567 1e-07
HHMJEDOE_01568 1.4e-53 yodL S YodL-like
HHMJEDOE_01569 3.1e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HHMJEDOE_01570 6.3e-24 yozD S YozD-like protein
HHMJEDOE_01572 1.6e-123 yodN
HHMJEDOE_01573 9.1e-36 yozE S Belongs to the UPF0346 family
HHMJEDOE_01574 5e-44 yokU S YokU-like protein, putative antitoxin
HHMJEDOE_01575 8.8e-270 kamA 5.4.3.2 E lysine 2,3-aminomutase
HHMJEDOE_01576 9.4e-139 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HHMJEDOE_01577 6.5e-251 yodQ 3.5.1.16 E Acetylornithine deacetylase
HHMJEDOE_01578 3.6e-109 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHMJEDOE_01579 4.2e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHMJEDOE_01580 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHMJEDOE_01582 7e-136 yiiD K acetyltransferase
HHMJEDOE_01583 1.1e-229 cgeD M maturation of the outermost layer of the spore
HHMJEDOE_01584 6.3e-32 cgeC
HHMJEDOE_01585 8.2e-53 cgeA
HHMJEDOE_01586 2.2e-168 cgeB S Spore maturation protein
HHMJEDOE_01587 5.6e-198 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HHMJEDOE_01588 2.4e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
HHMJEDOE_01589 3.2e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHMJEDOE_01590 1.2e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHMJEDOE_01591 1.8e-69 ypoP K transcriptional
HHMJEDOE_01592 8.7e-219 mepA V MATE efflux family protein
HHMJEDOE_01593 2.1e-28 ypmT S Uncharacterized ympT
HHMJEDOE_01594 3.3e-95 ypmS S protein conserved in bacteria
HHMJEDOE_01595 8.5e-134 ypmR E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_01596 1.2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HHMJEDOE_01597 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HHMJEDOE_01598 1.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HHMJEDOE_01599 9.5e-170 pspF K Transcriptional regulator
HHMJEDOE_01600 5.6e-107 hlyIII S protein, Hemolysin III
HHMJEDOE_01601 2.1e-103 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HHMJEDOE_01602 2.7e-88 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHMJEDOE_01603 2.1e-151 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHMJEDOE_01604 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HHMJEDOE_01605 1.4e-110 ypjP S YpjP-like protein
HHMJEDOE_01606 3.5e-135 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HHMJEDOE_01607 1.5e-74 yphP S Belongs to the UPF0403 family
HHMJEDOE_01608 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HHMJEDOE_01609 5.4e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
HHMJEDOE_01610 5.8e-101 ypgQ S phosphohydrolase
HHMJEDOE_01611 2.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HHMJEDOE_01612 1.7e-173 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HHMJEDOE_01613 3.4e-211 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HHMJEDOE_01614 7.9e-31 cspD K Cold-shock protein
HHMJEDOE_01615 4.5e-17 degR
HHMJEDOE_01616 1.6e-31 S Protein of unknown function (DUF2564)
HHMJEDOE_01617 2.4e-26 ypeQ S Zinc-finger
HHMJEDOE_01618 1e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HHMJEDOE_01619 7.2e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HHMJEDOE_01620 8.2e-64 rnhA 3.1.26.4 L Ribonuclease
HHMJEDOE_01622 1.6e-160 polA 2.7.7.7 L 5'3' exonuclease
HHMJEDOE_01624 2e-07
HHMJEDOE_01625 1.2e-36 ypbS S Protein of unknown function (DUF2533)
HHMJEDOE_01626 0.0 ypbR S Dynamin family
HHMJEDOE_01627 2.1e-80 ypbQ S protein conserved in bacteria
HHMJEDOE_01628 6.1e-194 bcsA Q Naringenin-chalcone synthase
HHMJEDOE_01629 3.1e-216 pbuX F xanthine
HHMJEDOE_01630 4.1e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHMJEDOE_01631 2.5e-286 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HHMJEDOE_01632 4.4e-167 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HHMJEDOE_01633 1.1e-99 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HHMJEDOE_01634 3.5e-177 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HHMJEDOE_01635 1.6e-175 ptxS K transcriptional
HHMJEDOE_01636 1.2e-154 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHMJEDOE_01637 6.1e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_01638 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HHMJEDOE_01640 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHMJEDOE_01641 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHMJEDOE_01642 6.3e-91 ypsA S Belongs to the UPF0398 family
HHMJEDOE_01643 1.5e-217 yprB L RNase_H superfamily
HHMJEDOE_01644 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HHMJEDOE_01645 2.4e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HHMJEDOE_01646 2.5e-63 hspX O Belongs to the small heat shock protein (HSP20) family
HHMJEDOE_01647 1.9e-30 yppG S YppG-like protein
HHMJEDOE_01649 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
HHMJEDOE_01652 9.5e-175 yppC S Protein of unknown function (DUF2515)
HHMJEDOE_01653 2.5e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHMJEDOE_01654 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HHMJEDOE_01655 4.2e-78 ypoC
HHMJEDOE_01656 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHMJEDOE_01657 2.2e-128 dnaD L DNA replication protein DnaD
HHMJEDOE_01658 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
HHMJEDOE_01659 7e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HHMJEDOE_01660 2.7e-77 ypmB S protein conserved in bacteria
HHMJEDOE_01661 4.3e-22 ypmA S Protein of unknown function (DUF4264)
HHMJEDOE_01662 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHMJEDOE_01663 1e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HHMJEDOE_01664 1.2e-147 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HHMJEDOE_01665 1.6e-146 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HHMJEDOE_01666 1.3e-176 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHMJEDOE_01667 1.2e-198 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHMJEDOE_01668 3e-204 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HHMJEDOE_01669 1.9e-124 bshB1 S proteins, LmbE homologs
HHMJEDOE_01670 5.7e-68 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HHMJEDOE_01671 7.2e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HHMJEDOE_01672 1e-54 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HHMJEDOE_01673 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HHMJEDOE_01674 2e-138 ypjB S sporulation protein
HHMJEDOE_01675 1.9e-95 ypjA S membrane
HHMJEDOE_01676 3.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HHMJEDOE_01677 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HHMJEDOE_01678 2.7e-96 qcrA C Menaquinol-cytochrome c reductase
HHMJEDOE_01679 2.1e-68 ypiF S Protein of unknown function (DUF2487)
HHMJEDOE_01680 1.8e-98 ypiB S Belongs to the UPF0302 family
HHMJEDOE_01681 4.9e-227 S COG0457 FOG TPR repeat
HHMJEDOE_01682 3e-224 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HHMJEDOE_01683 8.9e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HHMJEDOE_01684 3.6e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HHMJEDOE_01685 1e-134 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HHMJEDOE_01686 5.3e-223 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HHMJEDOE_01687 9.1e-105 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HHMJEDOE_01688 1.2e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HHMJEDOE_01689 3.2e-173 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HHMJEDOE_01690 1e-279 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HHMJEDOE_01691 9.6e-62 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HHMJEDOE_01692 1.4e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HHMJEDOE_01693 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HHMJEDOE_01694 4.5e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HHMJEDOE_01695 4.5e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HHMJEDOE_01696 5.4e-192 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHMJEDOE_01697 5.2e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHMJEDOE_01698 5.3e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HHMJEDOE_01699 3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HHMJEDOE_01700 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HHMJEDOE_01701 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHMJEDOE_01702 4.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HHMJEDOE_01703 2.1e-129 yphF
HHMJEDOE_01704 6.3e-20 yphE S Protein of unknown function (DUF2768)
HHMJEDOE_01705 2.4e-176 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHMJEDOE_01706 1.4e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHMJEDOE_01707 1.3e-27 ypzH
HHMJEDOE_01708 4.7e-160 seaA S YIEGIA protein
HHMJEDOE_01709 8.4e-97 yphA
HHMJEDOE_01710 1e-07 S YpzI-like protein
HHMJEDOE_01711 1.1e-173 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHMJEDOE_01712 6.2e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HHMJEDOE_01713 1.3e-109 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHMJEDOE_01714 2e-22 S Family of unknown function (DUF5359)
HHMJEDOE_01715 2.6e-99 ypfA M Flagellar protein YcgR
HHMJEDOE_01716 1.6e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HHMJEDOE_01717 1.7e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HHMJEDOE_01718 1.8e-116 prsW S Involved in the degradation of specific anti-sigma factors
HHMJEDOE_01719 7.9e-169 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HHMJEDOE_01720 9.8e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHMJEDOE_01721 1.2e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HHMJEDOE_01722 7.5e-138 ypbG S Calcineurin-like phosphoesterase superfamily domain
HHMJEDOE_01723 2.5e-77 ypbF S Protein of unknown function (DUF2663)
HHMJEDOE_01724 4.6e-68 ypbE M Lysin motif
HHMJEDOE_01725 2e-85 ypbD S metal-dependent membrane protease
HHMJEDOE_01726 2.4e-273 recQ 3.6.4.12 L DNA helicase
HHMJEDOE_01727 4.6e-186 ypbB 5.1.3.1 S protein conserved in bacteria
HHMJEDOE_01728 4.7e-41 fer C Ferredoxin
HHMJEDOE_01729 3e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHMJEDOE_01730 1.3e-09
HHMJEDOE_01731 2.9e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHMJEDOE_01732 2.3e-123 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HHMJEDOE_01733 2.1e-178 rsiX
HHMJEDOE_01734 8.5e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_01735 0.0 resE 2.7.13.3 T Histidine kinase
HHMJEDOE_01736 9.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_01737 3.2e-209 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HHMJEDOE_01738 9.9e-310 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HHMJEDOE_01739 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HHMJEDOE_01740 1.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHMJEDOE_01741 7.1e-87 spmB S Spore maturation protein
HHMJEDOE_01742 3.5e-103 spmA S Spore maturation protein
HHMJEDOE_01743 2.3e-204 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HHMJEDOE_01744 2.3e-93 ypuI S Protein of unknown function (DUF3907)
HHMJEDOE_01745 1.3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHMJEDOE_01746 5.3e-125 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHMJEDOE_01747 1.5e-81 ypuF S Domain of unknown function (DUF309)
HHMJEDOE_01748 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_01749 6.6e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHMJEDOE_01750 1.9e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HHMJEDOE_01751 9.1e-113 ribE 2.5.1.9 H Riboflavin synthase
HHMJEDOE_01752 2.1e-194 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHMJEDOE_01753 3.6e-52
HHMJEDOE_01754 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HHMJEDOE_01756 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HHMJEDOE_01758 4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHMJEDOE_01759 3.4e-147 ypuA S Secreted protein
HHMJEDOE_01760 1.2e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HHMJEDOE_01761 9.5e-267 spoVAF EG Stage V sporulation protein AF
HHMJEDOE_01762 9.8e-109 spoVAEA S stage V sporulation protein
HHMJEDOE_01763 2.2e-57 spoVAEB S stage V sporulation protein
HHMJEDOE_01764 1.1e-186 spoVAD I Stage V sporulation protein AD
HHMJEDOE_01765 2.3e-78 spoVAC S stage V sporulation protein AC
HHMJEDOE_01766 2.5e-66 spoVAB S Stage V sporulation protein AB
HHMJEDOE_01767 2.9e-108 spoVAA S Stage V sporulation protein AA
HHMJEDOE_01768 7.7e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_01769 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HHMJEDOE_01770 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HHMJEDOE_01771 6.7e-207 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HHMJEDOE_01772 1.6e-146 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HHMJEDOE_01773 4.1e-228 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHMJEDOE_01774 2.2e-165 xerD L recombinase XerD
HHMJEDOE_01775 1.1e-36 S Protein of unknown function (DUF4227)
HHMJEDOE_01776 2.4e-80 fur P Belongs to the Fur family
HHMJEDOE_01777 9.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HHMJEDOE_01778 1.9e-26 yqkK
HHMJEDOE_01779 9.2e-237 mleA 1.1.1.38 C malic enzyme
HHMJEDOE_01780 2.4e-227 mleN C Na H antiporter
HHMJEDOE_01781 8.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HHMJEDOE_01782 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase
HHMJEDOE_01783 1.5e-56 ansR K Transcriptional regulator
HHMJEDOE_01784 9.9e-211 yqxK 3.6.4.12 L DNA helicase
HHMJEDOE_01785 7.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HHMJEDOE_01787 9.1e-159 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HHMJEDOE_01788 5.5e-09 yqkE S Protein of unknown function (DUF3886)
HHMJEDOE_01789 7.7e-158 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HHMJEDOE_01790 3.6e-38 yqkC S Protein of unknown function (DUF2552)
HHMJEDOE_01791 2.8e-54 yqkB S Belongs to the HesB IscA family
HHMJEDOE_01792 4.3e-173 yqkA K GrpB protein
HHMJEDOE_01793 9.8e-50 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HHMJEDOE_01794 2e-85 yqjY K acetyltransferase
HHMJEDOE_01795 1.5e-50 S YolD-like protein
HHMJEDOE_01796 5.6e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHMJEDOE_01798 4.3e-212 yqjV G Major Facilitator Superfamily
HHMJEDOE_01800 7.7e-67 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHMJEDOE_01801 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HHMJEDOE_01802 8.5e-238 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HHMJEDOE_01803 5.2e-139 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_01804 2.1e-166 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HHMJEDOE_01805 1.1e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHMJEDOE_01806 3.4e-297 rocB E arginine degradation protein
HHMJEDOE_01807 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HHMJEDOE_01808 9.6e-138 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHMJEDOE_01809 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHMJEDOE_01810 1.4e-167 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHMJEDOE_01811 6.5e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHMJEDOE_01812 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHMJEDOE_01813 2e-225 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHMJEDOE_01814 4.7e-24 yqzJ
HHMJEDOE_01815 6.5e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHMJEDOE_01816 3.2e-130 yqjF S Uncharacterized conserved protein (COG2071)
HHMJEDOE_01817 4.9e-199 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HHMJEDOE_01818 3.7e-274 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HHMJEDOE_01819 3.5e-65 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HHMJEDOE_01821 2.3e-93 yqjB S protein conserved in bacteria
HHMJEDOE_01822 1.9e-170 yqjA S Putative aromatic acid exporter C-terminal domain
HHMJEDOE_01823 1.6e-126 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HHMJEDOE_01824 2.1e-104 artQ E COG0765 ABC-type amino acid transport system, permease component
HHMJEDOE_01825 2.5e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
HHMJEDOE_01826 3e-75 yqiW S Belongs to the UPF0403 family
HHMJEDOE_01827 2.2e-157 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHMJEDOE_01828 2.5e-201 norA EGP Major facilitator Superfamily
HHMJEDOE_01829 8e-146 bmrR K helix_turn_helix, mercury resistance
HHMJEDOE_01830 2.5e-215 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHMJEDOE_01831 3.3e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHMJEDOE_01832 1e-184 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHMJEDOE_01833 4e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHMJEDOE_01834 2.6e-197 buk 2.7.2.7 C Belongs to the acetokinase family
HHMJEDOE_01835 4.5e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HHMJEDOE_01836 1.7e-146 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HHMJEDOE_01837 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HHMJEDOE_01838 9.3e-31 yqzF S Protein of unknown function (DUF2627)
HHMJEDOE_01839 9.6e-153 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HHMJEDOE_01840 3.6e-263 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HHMJEDOE_01841 4.4e-200 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HHMJEDOE_01842 2e-203 mmgC I acyl-CoA dehydrogenase
HHMJEDOE_01843 1.7e-146 hbdA 1.1.1.157 I Dehydrogenase
HHMJEDOE_01844 2.8e-205 mmgA 2.3.1.9 I Belongs to the thiolase family
HHMJEDOE_01845 1.1e-117 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHMJEDOE_01846 1.6e-103 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HHMJEDOE_01847 1.9e-25
HHMJEDOE_01848 1.7e-207 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HHMJEDOE_01851 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HHMJEDOE_01852 1.2e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
HHMJEDOE_01853 3.8e-283 recN L May be involved in recombinational repair of damaged DNA
HHMJEDOE_01854 1.1e-77 argR K Regulates arginine biosynthesis genes
HHMJEDOE_01855 2.4e-153 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HHMJEDOE_01856 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HHMJEDOE_01857 5.2e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHMJEDOE_01858 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHMJEDOE_01859 7.4e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHMJEDOE_01860 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHMJEDOE_01861 1.3e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHMJEDOE_01862 2.4e-66 yqhY S protein conserved in bacteria
HHMJEDOE_01863 5e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HHMJEDOE_01864 4.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHMJEDOE_01865 7.9e-80 spoIIIAH S SpoIIIAH-like protein
HHMJEDOE_01866 1e-106 spoIIIAG S stage III sporulation protein AG
HHMJEDOE_01867 1.2e-98 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HHMJEDOE_01868 1.5e-193 spoIIIAE S stage III sporulation protein AE
HHMJEDOE_01869 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HHMJEDOE_01870 7.6e-29 spoIIIAC S stage III sporulation protein AC
HHMJEDOE_01871 2.3e-82 spoIIIAB S Stage III sporulation protein
HHMJEDOE_01872 6.1e-163 spoIIIAA S stage III sporulation protein AA
HHMJEDOE_01873 1e-36 yqhV S Protein of unknown function (DUF2619)
HHMJEDOE_01874 2.7e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHMJEDOE_01875 3e-169 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HHMJEDOE_01876 1e-75 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HHMJEDOE_01877 1.2e-89 yqhR S Conserved membrane protein YqhR
HHMJEDOE_01878 2.2e-171 yqhQ S Protein of unknown function (DUF1385)
HHMJEDOE_01879 1.1e-60 yqhP
HHMJEDOE_01880 1.9e-161 yqhO S esterase of the alpha-beta hydrolase superfamily
HHMJEDOE_01881 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HHMJEDOE_01882 2.4e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HHMJEDOE_01883 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
HHMJEDOE_01884 2.3e-281 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHMJEDOE_01885 4.9e-246 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HHMJEDOE_01886 1.3e-191 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HHMJEDOE_01887 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHMJEDOE_01888 9e-147 yqhG S Bacterial protein YqhG of unknown function
HHMJEDOE_01889 2.6e-22 sinI S Anti-repressor SinI
HHMJEDOE_01890 1e-54 sinR K transcriptional
HHMJEDOE_01891 8.4e-137 tasA S Cell division protein FtsN
HHMJEDOE_01892 1.1e-56 sipW 3.4.21.89 U Signal peptidase
HHMJEDOE_01893 2.7e-100 yqxM
HHMJEDOE_01894 7.7e-52 yqzG S Protein of unknown function (DUF3889)
HHMJEDOE_01895 2.6e-25 yqzE S YqzE-like protein
HHMJEDOE_01896 2.1e-45 S ComG operon protein 7
HHMJEDOE_01897 1.5e-45 comGE
HHMJEDOE_01898 9.5e-58 gspH NU protein transport across the cell outer membrane
HHMJEDOE_01899 5.2e-47 comGC U Required for transformation and DNA binding
HHMJEDOE_01900 6.9e-163 comGB NU COG1459 Type II secretory pathway, component PulF
HHMJEDOE_01901 6.4e-196 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HHMJEDOE_01902 9.1e-50 ylbB S Cbs domain
HHMJEDOE_01903 7.5e-156 corA P Mg2 transporter protein
HHMJEDOE_01904 5.7e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HHMJEDOE_01905 7.6e-136 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHMJEDOE_01907 1.2e-61 yqgZ 1.20.4.1 P Belongs to the ArsC family
HHMJEDOE_01908 5.3e-37 yqgY S Protein of unknown function (DUF2626)
HHMJEDOE_01909 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HHMJEDOE_01910 4.4e-22 yqgW S Protein of unknown function (DUF2759)
HHMJEDOE_01911 1.5e-49 yqgV S Thiamine-binding protein
HHMJEDOE_01912 1.1e-168 yqgU
HHMJEDOE_01913 5.7e-203 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HHMJEDOE_01914 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHMJEDOE_01915 1.9e-178 glcK 2.7.1.2 G Glucokinase
HHMJEDOE_01916 3.4e-27 yqgQ S Protein conserved in bacteria
HHMJEDOE_01917 3.6e-221 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HHMJEDOE_01918 1.2e-08 yqgO
HHMJEDOE_01919 4.2e-90 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHMJEDOE_01920 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHMJEDOE_01921 1.3e-167 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HHMJEDOE_01923 1e-49 yqzD
HHMJEDOE_01924 5.6e-72 yqzC S YceG-like family
HHMJEDOE_01925 1.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHMJEDOE_01926 1.5e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHMJEDOE_01927 1.8e-156 pstA P Phosphate transport system permease
HHMJEDOE_01928 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HHMJEDOE_01929 1e-132 pstS P Phosphate
HHMJEDOE_01930 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HHMJEDOE_01931 2.6e-228 yqgE EGP Major facilitator superfamily
HHMJEDOE_01932 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HHMJEDOE_01933 2e-72 yqgC S protein conserved in bacteria
HHMJEDOE_01934 1.9e-125 yqgB S Protein of unknown function (DUF1189)
HHMJEDOE_01935 2.4e-44 yqfZ M LysM domain
HHMJEDOE_01936 2.4e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HHMJEDOE_01937 2.4e-60 yqfX S membrane
HHMJEDOE_01938 5.1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HHMJEDOE_01939 3e-75 zur P Belongs to the Fur family
HHMJEDOE_01940 6.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HHMJEDOE_01941 7.4e-34 yqfT S Protein of unknown function (DUF2624)
HHMJEDOE_01942 1.1e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHMJEDOE_01943 7.5e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHMJEDOE_01944 1.9e-26 yqfQ S YqfQ-like protein
HHMJEDOE_01945 2.3e-173 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HHMJEDOE_01946 4.6e-205 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHMJEDOE_01947 3.6e-109 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHMJEDOE_01948 3.8e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
HHMJEDOE_01949 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHMJEDOE_01950 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHMJEDOE_01951 2.7e-85 yaiI S Belongs to the UPF0178 family
HHMJEDOE_01952 4.1e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHMJEDOE_01953 4.5e-112 ccpN K CBS domain
HHMJEDOE_01954 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHMJEDOE_01955 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHMJEDOE_01956 5.9e-143 recO L Involved in DNA repair and RecF pathway recombination
HHMJEDOE_01957 4.2e-18 S YqzL-like protein
HHMJEDOE_01958 9.9e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHMJEDOE_01959 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHMJEDOE_01960 4.1e-57 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HHMJEDOE_01961 8.2e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHMJEDOE_01962 0.0 yqfF S membrane-associated HD superfamily hydrolase
HHMJEDOE_01964 3.6e-174 phoH T Phosphate starvation-inducible protein PhoH
HHMJEDOE_01965 3.9e-178 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HHMJEDOE_01966 4.6e-45 yqfC S sporulation protein YqfC
HHMJEDOE_01967 5.5e-10 yqfB
HHMJEDOE_01968 2.4e-120 yqfA S UPF0365 protein
HHMJEDOE_01969 5.6e-218 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HHMJEDOE_01970 2.5e-61 yqeY S Yqey-like protein
HHMJEDOE_01971 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHMJEDOE_01972 2.1e-153 yqeW P COG1283 Na phosphate symporter
HHMJEDOE_01973 9.7e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HHMJEDOE_01974 7e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHMJEDOE_01975 1.3e-173 prmA J Methylates ribosomal protein L11
HHMJEDOE_01976 3e-180 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHMJEDOE_01977 0.0 dnaK O Heat shock 70 kDa protein
HHMJEDOE_01978 1.6e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHMJEDOE_01979 7.5e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHMJEDOE_01980 3.1e-209 hemN H Involved in the biosynthesis of porphyrin-containing compound
HHMJEDOE_01981 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHMJEDOE_01982 1.2e-50 yqxA S Protein of unknown function (DUF3679)
HHMJEDOE_01983 1.8e-218 spoIIP M stage II sporulation protein P
HHMJEDOE_01984 1.7e-199 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HHMJEDOE_01985 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
HHMJEDOE_01986 1.2e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
HHMJEDOE_01987 0.0 comEC S Competence protein ComEC
HHMJEDOE_01988 5.7e-103 comEB 3.5.4.12 F ComE operon protein 2
HHMJEDOE_01989 1.4e-78 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HHMJEDOE_01990 6.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHMJEDOE_01991 1.2e-132 yqeM Q Methyltransferase
HHMJEDOE_01992 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHMJEDOE_01993 2.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HHMJEDOE_01994 2.9e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHMJEDOE_01995 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HHMJEDOE_01996 8.4e-151 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HHMJEDOE_01997 1.5e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HHMJEDOE_01998 5.3e-95 yqeG S hydrolase of the HAD superfamily
HHMJEDOE_02000 3.3e-135 yqeF E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_02001 1.6e-124 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHMJEDOE_02002 8e-98 yqeD S SNARE associated Golgi protein
HHMJEDOE_02003 3.1e-33 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HHMJEDOE_02004 8e-29 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HHMJEDOE_02005 1.6e-110 yqeB
HHMJEDOE_02006 7.4e-68 nucB M Deoxyribonuclease NucA/NucB
HHMJEDOE_02007 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_02008 2.5e-278 cisA2 L Recombinase
HHMJEDOE_02009 1.7e-143
HHMJEDOE_02010 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HHMJEDOE_02014 1.1e-129 S Aspartate phosphatase response regulator
HHMJEDOE_02015 1.3e-138 yvgN 1.1.1.346 S Reductase
HHMJEDOE_02016 1.5e-69 K MerR family transcriptional regulator
HHMJEDOE_02017 1.2e-272 L nucleic acid phosphodiester bond hydrolysis
HHMJEDOE_02019 2.6e-125 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHMJEDOE_02020 6.4e-67 S Bacteriophage holin family
HHMJEDOE_02021 3.6e-58 adk 2.7.4.3 F adenylate kinase activity
HHMJEDOE_02023 1e-90 yqaB E IrrE N-terminal-like domain
HHMJEDOE_02024 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_02026 1.8e-95 ywrO S Flavodoxin-like fold
HHMJEDOE_02027 9.1e-78 S Protein of unknown function with HXXEE motif
HHMJEDOE_02028 4.7e-62 hosA K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_02029 3.2e-60 2.8.1.7, 4.4.1.16 P Rhodanese Homology Domain
HHMJEDOE_02030 6.2e-53 ydcG S EVE domain
HHMJEDOE_02032 9.4e-150 S Serine aminopeptidase, S33
HHMJEDOE_02034 1e-77 yijE EG EamA-like transporter family
HHMJEDOE_02035 1.3e-24 K MerR HTH family regulatory protein
HHMJEDOE_02037 8.6e-71 ylbE GM Nucleoside-diphosphate-sugar epimerases
HHMJEDOE_02039 1.2e-128 S Aspartate phosphatase response regulator
HHMJEDOE_02042 9.5e-09 L nucleic acid phosphodiester bond hydrolysis
HHMJEDOE_02043 3e-61 L nucleic acid phosphodiester bond hydrolysis
HHMJEDOE_02044 7.7e-29
HHMJEDOE_02045 1.6e-39
HHMJEDOE_02046 2e-68 psiE S Protein PsiE homolog
HHMJEDOE_02047 3.9e-232 yrkQ T Histidine kinase
HHMJEDOE_02048 1.3e-125 T Transcriptional regulator
HHMJEDOE_02049 1.3e-202 yrkO P Protein of unknown function (DUF418)
HHMJEDOE_02050 1.4e-98 yrkN K Acetyltransferase (GNAT) family
HHMJEDOE_02051 5.2e-12 L COG2963 Transposase and inactivated derivatives
HHMJEDOE_02052 3.6e-11 yodA S tautomerase
HHMJEDOE_02053 1e-82 yvbV1 EG Permeases of the drug metabolite transporter (DMT) superfamily
HHMJEDOE_02054 2.7e-54 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHMJEDOE_02055 6.9e-148 gltR K LysR substrate binding domain
HHMJEDOE_02056 2.8e-180 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HHMJEDOE_02057 1.8e-128 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHMJEDOE_02058 1.3e-216 cypA C Cytochrome P450
HHMJEDOE_02060 6.5e-67 K Transcriptional regulator
HHMJEDOE_02061 8.4e-163 scrR K transcriptional
HHMJEDOE_02062 4.2e-226 msmE G Bacterial extracellular solute-binding protein
HHMJEDOE_02063 1.1e-148 msmF P Binding-protein-dependent transport system inner membrane component
HHMJEDOE_02064 2.5e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HHMJEDOE_02065 8.8e-197 rafB P LacY proton/sugar symporter
HHMJEDOE_02066 2.1e-250 cscA 3.2.1.26 GH32 G invertase
HHMJEDOE_02067 1.6e-158 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HHMJEDOE_02068 2.7e-152 rhaS5 K AraC-like ligand binding domain
HHMJEDOE_02069 1.5e-86 yrdA S DinB family
HHMJEDOE_02070 3.9e-78 bltD 2.3.1.57 K FR47-like protein
HHMJEDOE_02071 1.6e-29 aadK G Streptomycin adenylyltransferase
HHMJEDOE_02072 7.4e-107 aadK G Streptomycin adenylyltransferase
HHMJEDOE_02073 6.2e-99 K helix_turn_helix gluconate operon transcriptional repressor
HHMJEDOE_02075 3.3e-210 rbtT P Major Facilitator Superfamily
HHMJEDOE_02076 1.1e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_02077 1.9e-151 2.2.1.1 G Transketolase, pyrimidine binding domain
HHMJEDOE_02078 8.3e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
HHMJEDOE_02079 5.7e-103 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HHMJEDOE_02080 3.3e-218 yraO C Citrate transporter
HHMJEDOE_02081 2.6e-155 yraN K Transcriptional regulator
HHMJEDOE_02082 9.5e-195 yraM S PrpF protein
HHMJEDOE_02084 1.9e-147 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HHMJEDOE_02086 1.9e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_02087 7.6e-128 S Alpha beta hydrolase
HHMJEDOE_02088 1.1e-34 yraG
HHMJEDOE_02089 1.8e-60 yraF M Spore coat protein
HHMJEDOE_02090 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHMJEDOE_02091 7.5e-26 yraE
HHMJEDOE_02092 6.8e-47 yraD M Spore coat protein
HHMJEDOE_02093 7.1e-14 ptsH G phosphocarrier protein HPr
HHMJEDOE_02094 8e-12 rmeD K MerR family transcriptional regulator
HHMJEDOE_02095 2.2e-40 yraB K helix_turn_helix, mercury resistance
HHMJEDOE_02096 4.3e-189 adhA 1.1.1.1 C alcohol dehydrogenase
HHMJEDOE_02097 2.1e-88 yhbO 1.11.1.6, 3.5.1.124 S protease
HHMJEDOE_02098 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HHMJEDOE_02099 2.6e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HHMJEDOE_02100 2.4e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HHMJEDOE_02101 2.9e-79 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HHMJEDOE_02102 1.2e-68 levD 2.7.1.202 G PTS system fructose IIA component
HHMJEDOE_02103 0.0 levR K PTS system fructose IIA component
HHMJEDOE_02105 2.6e-242 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_02106 6.6e-100 yrhP E LysE type translocator
HHMJEDOE_02107 2.7e-146 yrhO K Archaeal transcriptional regulator TrmB
HHMJEDOE_02108 1.1e-38 yrhK S YrhK-like protein
HHMJEDOE_02109 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HHMJEDOE_02110 1.5e-98 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HHMJEDOE_02111 4.2e-87 yrhH Q methyltransferase
HHMJEDOE_02113 1.4e-139 focA P Formate nitrite
HHMJEDOE_02114 5.6e-59 yrhF S Uncharacterized conserved protein (DUF2294)
HHMJEDOE_02115 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HHMJEDOE_02116 3e-76 yrhD S Protein of unknown function (DUF1641)
HHMJEDOE_02118 1.9e-181 trkA P Oxidoreductase
HHMJEDOE_02119 3.9e-149 czcD P COG1230 Co Zn Cd efflux system component
HHMJEDOE_02120 5.7e-203 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HHMJEDOE_02121 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HHMJEDOE_02122 3e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHMJEDOE_02123 8.1e-114 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HHMJEDOE_02124 2.9e-25 yrzA S Protein of unknown function (DUF2536)
HHMJEDOE_02125 1e-53 yrrS S Protein of unknown function (DUF1510)
HHMJEDOE_02126 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HHMJEDOE_02127 4.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHMJEDOE_02128 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HHMJEDOE_02129 4.4e-244 yegQ O COG0826 Collagenase and related proteases
HHMJEDOE_02130 8.3e-168 yegQ O Peptidase U32
HHMJEDOE_02131 6.1e-117 yrrM 2.1.1.104 S O-methyltransferase
HHMJEDOE_02132 8.7e-177 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHMJEDOE_02133 1.5e-43 yrzB S Belongs to the UPF0473 family
HHMJEDOE_02134 1.5e-68 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHMJEDOE_02135 1.7e-41 yrzL S Belongs to the UPF0297 family
HHMJEDOE_02136 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHMJEDOE_02137 2.9e-164 yrrI S AI-2E family transporter
HHMJEDOE_02138 3.6e-08 S Protein of unknown function (DUF3918)
HHMJEDOE_02139 9.8e-31 yrzR
HHMJEDOE_02140 5.1e-90 yrrD S protein conserved in bacteria
HHMJEDOE_02141 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHMJEDOE_02142 1.4e-15 S COG0457 FOG TPR repeat
HHMJEDOE_02143 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHMJEDOE_02144 3e-204 iscS 2.8.1.7 E Cysteine desulfurase
HHMJEDOE_02145 1.2e-70 cymR K Transcriptional regulator
HHMJEDOE_02146 5.9e-233 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HHMJEDOE_02147 3.8e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HHMJEDOE_02148 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HHMJEDOE_02149 7.7e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHMJEDOE_02151 4.4e-246 lytH 3.5.1.28 M COG3103 SH3 domain protein
HHMJEDOE_02152 8.5e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHMJEDOE_02153 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHMJEDOE_02154 3.2e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHMJEDOE_02155 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHMJEDOE_02156 1.2e-44 yrvD S Lipopolysaccharide assembly protein A domain
HHMJEDOE_02157 3.1e-76 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HHMJEDOE_02158 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HHMJEDOE_02159 1.8e-47 yrzD S Post-transcriptional regulator
HHMJEDOE_02160 2.7e-264 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_02161 1.9e-105 yrbG S membrane
HHMJEDOE_02162 1.7e-73 yrzE S Protein of unknown function (DUF3792)
HHMJEDOE_02163 6.7e-38 yajC U Preprotein translocase subunit YajC
HHMJEDOE_02164 5.7e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHMJEDOE_02165 1.1e-189 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHMJEDOE_02166 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HHMJEDOE_02167 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHMJEDOE_02168 2.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHMJEDOE_02169 8.9e-87 bofC S BofC C-terminal domain
HHMJEDOE_02170 8.2e-246 csbX EGP Major facilitator Superfamily
HHMJEDOE_02171 1.6e-183 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HHMJEDOE_02172 7.4e-115 yrzF T serine threonine protein kinase
HHMJEDOE_02174 5.5e-50 S Family of unknown function (DUF5412)
HHMJEDOE_02175 3.7e-247 alsT E Sodium alanine symporter
HHMJEDOE_02176 4.4e-116 yebC K transcriptional regulatory protein
HHMJEDOE_02177 2.7e-42 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHMJEDOE_02178 2.3e-111 safA M spore coat assembly protein SafA
HHMJEDOE_02179 7.3e-203 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HHMJEDOE_02180 1.6e-128 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HHMJEDOE_02181 1.1e-268 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HHMJEDOE_02182 2.8e-208 nifS 2.8.1.7 E Cysteine desulfurase
HHMJEDOE_02183 1.8e-90 niaR S small molecule binding protein (contains 3H domain)
HHMJEDOE_02184 1.9e-161 pheA 4.2.1.51 E Prephenate dehydratase
HHMJEDOE_02185 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HHMJEDOE_02186 2.1e-225 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHMJEDOE_02187 7.6e-103 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HHMJEDOE_02188 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHMJEDOE_02189 4.1e-56 ysxB J ribosomal protein
HHMJEDOE_02190 2.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHMJEDOE_02191 2.1e-157 spoIVFB S Stage IV sporulation protein
HHMJEDOE_02192 2.3e-142 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HHMJEDOE_02193 3.1e-142 minD D Belongs to the ParA family
HHMJEDOE_02194 4e-119 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHMJEDOE_02195 9.3e-84 mreD M shape-determining protein
HHMJEDOE_02196 2.9e-154 mreC M Involved in formation and maintenance of cell shape
HHMJEDOE_02197 5.3e-184 mreB D Rod shape-determining protein MreB
HHMJEDOE_02198 1.9e-124 radC E Belongs to the UPF0758 family
HHMJEDOE_02199 2.5e-98 maf D septum formation protein Maf
HHMJEDOE_02200 4.9e-158 spoIIB S Sporulation related domain
HHMJEDOE_02201 1.6e-116 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HHMJEDOE_02202 2.9e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHMJEDOE_02203 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHMJEDOE_02204 3.6e-25
HHMJEDOE_02205 2e-186 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HHMJEDOE_02206 5.8e-115 spoVID M stage VI sporulation protein D
HHMJEDOE_02207 1.5e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HHMJEDOE_02208 4.5e-180 hemB 4.2.1.24 H Belongs to the ALAD family
HHMJEDOE_02209 7.9e-135 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HHMJEDOE_02210 1.2e-169 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HHMJEDOE_02211 6.1e-146 hemX O cytochrome C
HHMJEDOE_02212 4.7e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HHMJEDOE_02213 7.8e-88 ysxD
HHMJEDOE_02214 9.8e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HHMJEDOE_02215 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HHMJEDOE_02216 4.3e-308 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HHMJEDOE_02217 5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHMJEDOE_02218 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHMJEDOE_02219 2e-183 ysoA H Tetratricopeptide repeat
HHMJEDOE_02220 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHMJEDOE_02221 4.5e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HHMJEDOE_02222 1e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HHMJEDOE_02223 1.6e-285 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HHMJEDOE_02224 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HHMJEDOE_02225 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HHMJEDOE_02226 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HHMJEDOE_02228 5.8e-74 ysnE K acetyltransferase
HHMJEDOE_02229 5.5e-123 ysnF S protein conserved in bacteria
HHMJEDOE_02231 7.2e-89 ysnB S Phosphoesterase
HHMJEDOE_02232 1.6e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHMJEDOE_02233 1.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HHMJEDOE_02234 3.5e-189 gerM S COG5401 Spore germination protein
HHMJEDOE_02235 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHMJEDOE_02236 2.5e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_02237 3.3e-30 gerE K Transcriptional regulator
HHMJEDOE_02238 2.1e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HHMJEDOE_02239 1.1e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HHMJEDOE_02240 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HHMJEDOE_02241 4.5e-106 sdhC C succinate dehydrogenase
HHMJEDOE_02242 1.2e-79 yslB S Protein of unknown function (DUF2507)
HHMJEDOE_02243 1.9e-204 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HHMJEDOE_02244 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHMJEDOE_02245 3.3e-52 trxA O Belongs to the thioredoxin family
HHMJEDOE_02246 1.3e-295 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HHMJEDOE_02247 8.4e-171 etfA C Electron transfer flavoprotein
HHMJEDOE_02248 3.8e-134 etfB C Electron transfer flavoprotein
HHMJEDOE_02249 2.3e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HHMJEDOE_02250 1.8e-96 fadR K Transcriptional regulator
HHMJEDOE_02251 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HHMJEDOE_02252 7.3e-68 yshE S membrane
HHMJEDOE_02253 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHMJEDOE_02254 0.0 polX L COG1796 DNA polymerase IV (family X)
HHMJEDOE_02255 1.4e-82 cvpA S membrane protein, required for colicin V production
HHMJEDOE_02256 6.5e-38 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHMJEDOE_02257 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHMJEDOE_02258 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHMJEDOE_02259 8.9e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHMJEDOE_02260 2.2e-123 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHMJEDOE_02261 7.6e-32 sspI S Belongs to the SspI family
HHMJEDOE_02262 1.6e-181 ysfB KT regulator
HHMJEDOE_02263 3.4e-253 glcD 1.1.3.15 C Glycolate oxidase subunit
HHMJEDOE_02264 4.9e-246 glcF C Glycolate oxidase
HHMJEDOE_02265 1.9e-54 ysfE 4.4.1.5 E Glyoxalase-like domain
HHMJEDOE_02266 0.0 cstA T Carbon starvation protein
HHMJEDOE_02267 4.3e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HHMJEDOE_02268 8.4e-143 araQ G transport system permease
HHMJEDOE_02269 3.5e-166 araP G carbohydrate transport
HHMJEDOE_02270 7.1e-250 araN G carbohydrate transport
HHMJEDOE_02271 5e-210 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HHMJEDOE_02272 6e-138 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HHMJEDOE_02273 2.1e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HHMJEDOE_02274 3.4e-305 araB 2.7.1.16 C Belongs to the ribulokinase family
HHMJEDOE_02275 1.9e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HHMJEDOE_02276 1e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HHMJEDOE_02277 1.7e-204 ysdC G COG1363 Cellulase M and related proteins
HHMJEDOE_02278 7.6e-51 ysdB S Sigma-w pathway protein YsdB
HHMJEDOE_02279 1.9e-43 ysdA S Membrane
HHMJEDOE_02280 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHMJEDOE_02281 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHMJEDOE_02282 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHMJEDOE_02284 7.7e-110 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HHMJEDOE_02285 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HHMJEDOE_02286 8e-126 lytT T COG3279 Response regulator of the LytR AlgR family
HHMJEDOE_02287 7.4e-311 lytS 2.7.13.3 T Histidine kinase
HHMJEDOE_02288 3.4e-146 ysaA S HAD-hyrolase-like
HHMJEDOE_02289 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHMJEDOE_02290 2.6e-152 ytxC S YtxC-like family
HHMJEDOE_02291 8.4e-103 ytxB S SNARE associated Golgi protein
HHMJEDOE_02292 6.3e-154 dnaI L Primosomal protein DnaI
HHMJEDOE_02293 1.4e-254 dnaB L Membrane attachment protein
HHMJEDOE_02294 3.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHMJEDOE_02295 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HHMJEDOE_02296 1.8e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHMJEDOE_02297 1.2e-64 ytcD K Transcriptional regulator
HHMJEDOE_02298 8.1e-200 ytbD EGP Major facilitator Superfamily
HHMJEDOE_02299 5.2e-153 ytbE S reductase
HHMJEDOE_02300 5.3e-91 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHMJEDOE_02301 7.3e-107 ytaF P Probably functions as a manganese efflux pump
HHMJEDOE_02302 1e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHMJEDOE_02303 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHMJEDOE_02304 2.9e-310 phoR 2.7.13.3 T Signal transduction histidine kinase
HHMJEDOE_02305 4.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_02306 6.9e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HHMJEDOE_02307 2e-241 icd 1.1.1.42 C isocitrate
HHMJEDOE_02308 3.4e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
HHMJEDOE_02309 5.2e-70 yeaL S membrane
HHMJEDOE_02310 3.5e-189 ytvI S sporulation integral membrane protein YtvI
HHMJEDOE_02311 2.8e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HHMJEDOE_02312 5.5e-306 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHMJEDOE_02313 3.7e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HHMJEDOE_02314 3.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HHMJEDOE_02315 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHMJEDOE_02316 4.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HHMJEDOE_02317 0.0 dnaE 2.7.7.7 L DNA polymerase
HHMJEDOE_02318 6e-55 ytrH S Sporulation protein YtrH
HHMJEDOE_02319 4.5e-67 ytrI
HHMJEDOE_02320 2e-28
HHMJEDOE_02321 1.7e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HHMJEDOE_02322 4.9e-45 ytpI S YtpI-like protein
HHMJEDOE_02323 3.9e-241 ytoI K transcriptional regulator containing CBS domains
HHMJEDOE_02324 2.1e-128 ytkL S Belongs to the UPF0173 family
HHMJEDOE_02325 3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_02327 2.1e-263 argH 4.3.2.1 E argininosuccinate lyase
HHMJEDOE_02328 6.7e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HHMJEDOE_02329 1.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HHMJEDOE_02330 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHMJEDOE_02331 5.9e-156 ytxK 2.1.1.72 L DNA methylase
HHMJEDOE_02332 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHMJEDOE_02333 6.3e-68 ytfJ S Sporulation protein YtfJ
HHMJEDOE_02334 3.8e-109 ytfI S Protein of unknown function (DUF2953)
HHMJEDOE_02335 1.9e-81 yteJ S RDD family
HHMJEDOE_02336 3.1e-176 sppA OU signal peptide peptidase SppA
HHMJEDOE_02337 2e-146 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHMJEDOE_02338 1.7e-293 ytcJ S amidohydrolase
HHMJEDOE_02339 9.2e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHMJEDOE_02340 1.1e-27 sasP S spore protein
HHMJEDOE_02341 1.8e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHMJEDOE_02342 9.8e-195 iscS2 2.8.1.7 E Cysteine desulfurase
HHMJEDOE_02343 5e-174 braB E Component of the transport system for branched-chain amino acids
HHMJEDOE_02344 1.3e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHMJEDOE_02345 2.4e-147 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HHMJEDOE_02346 1.2e-106 yttP K Transcriptional regulator
HHMJEDOE_02347 2.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HHMJEDOE_02348 1.2e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HHMJEDOE_02349 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHMJEDOE_02351 2e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHMJEDOE_02352 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HHMJEDOE_02353 2.8e-119 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HHMJEDOE_02354 5.3e-113 acuB S Domain in cystathionine beta-synthase and other proteins.
HHMJEDOE_02355 1.1e-214 acuC BQ histone deacetylase
HHMJEDOE_02356 4e-117 motS N Flagellar motor protein
HHMJEDOE_02357 5.3e-142 motA N flagellar motor
HHMJEDOE_02358 1.9e-181 ccpA K catabolite control protein A
HHMJEDOE_02359 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HHMJEDOE_02360 7.7e-52 ytxJ O Protein of unknown function (DUF2847)
HHMJEDOE_02361 6.5e-17 ytxH S COG4980 Gas vesicle protein
HHMJEDOE_02362 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHMJEDOE_02363 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHMJEDOE_02364 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HHMJEDOE_02365 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHMJEDOE_02366 7.8e-146 ytpQ S Belongs to the UPF0354 family
HHMJEDOE_02367 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHMJEDOE_02368 3.8e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HHMJEDOE_02369 8.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HHMJEDOE_02370 4.9e-51 ytzB S small secreted protein
HHMJEDOE_02371 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HHMJEDOE_02372 9.6e-147 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HHMJEDOE_02373 6.4e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHMJEDOE_02374 2e-45 ytzH S YtzH-like protein
HHMJEDOE_02375 4.6e-151 ytmP 2.7.1.89 M Phosphotransferase
HHMJEDOE_02376 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HHMJEDOE_02377 3.5e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HHMJEDOE_02378 6.9e-159 ytlQ
HHMJEDOE_02379 7.5e-92 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HHMJEDOE_02380 1.5e-169 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HHMJEDOE_02381 2e-258 pepV 3.5.1.18 E Dipeptidase
HHMJEDOE_02382 3.1e-221 pbuO S permease
HHMJEDOE_02383 9.6e-182 ythQ U Bacterial ABC transporter protein EcsB
HHMJEDOE_02384 3e-125 ythP V ABC transporter
HHMJEDOE_02385 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HHMJEDOE_02386 1.9e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHMJEDOE_02387 7.2e-284 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_02388 3.5e-233 ytfP S HI0933-like protein
HHMJEDOE_02389 7.3e-270 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HHMJEDOE_02390 3.1e-26 yteV S Sporulation protein Cse60
HHMJEDOE_02391 2.1e-104 yteU S Integral membrane protein
HHMJEDOE_02392 2e-244 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HHMJEDOE_02393 8.1e-62 yteS G transport
HHMJEDOE_02394 3.2e-214 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HHMJEDOE_02395 3.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HHMJEDOE_02396 0.0 ytdP K Transcriptional regulator
HHMJEDOE_02397 2.1e-282 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HHMJEDOE_02398 1.7e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HHMJEDOE_02399 4.2e-133 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HHMJEDOE_02400 1.8e-199 bioI 1.14.14.46 C Cytochrome P450
HHMJEDOE_02401 3.6e-185 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HHMJEDOE_02402 9.4e-116 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HHMJEDOE_02403 7.2e-193 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HHMJEDOE_02404 6.2e-249 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HHMJEDOE_02405 1.1e-133 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HHMJEDOE_02406 3.1e-60 S Psort location CytoplasmicMembrane, score
HHMJEDOE_02407 2.9e-157 ytaP S Acetyl xylan esterase (AXE1)
HHMJEDOE_02408 2.8e-180 msmR K Transcriptional regulator
HHMJEDOE_02409 1.5e-231 msmE G Bacterial extracellular solute-binding protein
HHMJEDOE_02410 1.1e-164 amyD P ABC transporter
HHMJEDOE_02411 1.9e-139 amyC P ABC transporter (permease)
HHMJEDOE_02412 1.5e-247 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HHMJEDOE_02413 8.1e-51 ytwF P Sulfurtransferase
HHMJEDOE_02414 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHMJEDOE_02415 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HHMJEDOE_02416 8.4e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HHMJEDOE_02417 5.2e-207 yttB EGP Major facilitator Superfamily
HHMJEDOE_02418 5.3e-37 yttA 2.7.13.3 S Pfam Transposase IS66
HHMJEDOE_02419 0.0 bceB V ABC transporter (permease)
HHMJEDOE_02420 4.5e-135 bceA V ABC transporter, ATP-binding protein
HHMJEDOE_02421 4.6e-172 T PhoQ Sensor
HHMJEDOE_02422 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_02423 5.7e-231 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HHMJEDOE_02424 4.5e-126 ytrE V ABC transporter, ATP-binding protein
HHMJEDOE_02425 1.6e-153
HHMJEDOE_02426 4.6e-140 P ABC-2 family transporter protein
HHMJEDOE_02427 2.1e-160 ytrB P abc transporter atp-binding protein
HHMJEDOE_02428 1.8e-63 ytrA K GntR family transcriptional regulator
HHMJEDOE_02430 5.1e-41 ytzC S Protein of unknown function (DUF2524)
HHMJEDOE_02431 3.7e-187 yhcC S Fe-S oxidoreductase
HHMJEDOE_02432 5e-102 ytqB J Putative rRNA methylase
HHMJEDOE_02433 2e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HHMJEDOE_02434 4.9e-145 ytpA 3.1.1.5 I Alpha beta hydrolase
HHMJEDOE_02435 2.4e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HHMJEDOE_02436 1.1e-240 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_02437 0.0 asnB 6.3.5.4 E Asparagine synthase
HHMJEDOE_02438 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHMJEDOE_02439 7.2e-305 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HHMJEDOE_02440 6.1e-38 ytmB S Protein of unknown function (DUF2584)
HHMJEDOE_02441 7.7e-143 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HHMJEDOE_02442 7.3e-181 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HHMJEDOE_02443 7.8e-143 ytlC P ABC transporter
HHMJEDOE_02444 4.6e-138 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HHMJEDOE_02445 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HHMJEDOE_02446 2e-62 ytkC S Bacteriophage holin family
HHMJEDOE_02447 1e-75 dps P Belongs to the Dps family
HHMJEDOE_02449 3.5e-68 ytkA S YtkA-like
HHMJEDOE_02450 1.3e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHMJEDOE_02451 3.6e-97 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HHMJEDOE_02452 3.6e-41 rpmE2 J Ribosomal protein L31
HHMJEDOE_02453 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HHMJEDOE_02454 5.8e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HHMJEDOE_02455 3.3e-24 S Domain of Unknown Function (DUF1540)
HHMJEDOE_02456 1.8e-143 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HHMJEDOE_02457 1.2e-209 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHMJEDOE_02458 2.7e-132 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHMJEDOE_02459 3.1e-159 troA P Belongs to the bacterial solute-binding protein 9 family
HHMJEDOE_02460 1.8e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HHMJEDOE_02461 2.2e-260 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHMJEDOE_02462 3.5e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHMJEDOE_02463 1.7e-140 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HHMJEDOE_02464 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HHMJEDOE_02465 3.7e-256 menF 5.4.4.2 HQ Isochorismate synthase
HHMJEDOE_02466 2.4e-130 dksA T COG1734 DnaK suppressor protein
HHMJEDOE_02467 2.4e-139 galU 2.7.7.9 M Nucleotidyl transferase
HHMJEDOE_02468 1e-224 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHMJEDOE_02469 2e-169 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HHMJEDOE_02470 2.1e-219 ytcC M Glycosyltransferase Family 4
HHMJEDOE_02472 6.7e-198 cotS S Seems to be required for the assembly of the CotSA protein in spores
HHMJEDOE_02473 4.5e-208 cotSA M Glycosyl transferases group 1
HHMJEDOE_02474 8.8e-198 cotI S Spore coat protein
HHMJEDOE_02475 6.9e-70 tspO T membrane
HHMJEDOE_02476 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HHMJEDOE_02477 6.1e-266 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HHMJEDOE_02478 2.8e-172 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HHMJEDOE_02479 5.2e-188 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HHMJEDOE_02480 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HHMJEDOE_02489 7.8e-08
HHMJEDOE_02490 1.3e-09
HHMJEDOE_02497 2e-08
HHMJEDOE_02502 3.4e-39 S COG NOG14552 non supervised orthologous group
HHMJEDOE_02503 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHMJEDOE_02504 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHMJEDOE_02505 1.8e-37 yaaB S Domain of unknown function (DUF370)
HHMJEDOE_02506 8.6e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHMJEDOE_02507 6.9e-33 yaaA S S4 domain
HHMJEDOE_02508 4e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHMJEDOE_02509 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHMJEDOE_02510 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHMJEDOE_02511 5.1e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHMJEDOE_02512 1.3e-100 jag S single-stranded nucleic acid binding R3H
HHMJEDOE_02513 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHMJEDOE_02514 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHMJEDOE_02515 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HHMJEDOE_02516 1.4e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HHMJEDOE_02517 1.1e-64 S Bacterial PH domain
HHMJEDOE_02518 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HHMJEDOE_02519 3.7e-146 spo0J K Belongs to the ParB family
HHMJEDOE_02520 2.4e-107 yyaC S Sporulation protein YyaC
HHMJEDOE_02521 8.2e-177 yyaD S Membrane
HHMJEDOE_02522 9.6e-32 yyzM S protein conserved in bacteria
HHMJEDOE_02523 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHMJEDOE_02524 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHMJEDOE_02525 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HHMJEDOE_02526 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHMJEDOE_02527 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHMJEDOE_02528 9.6e-138 xth 3.1.11.2 L exodeoxyribonuclease III
HHMJEDOE_02529 4.4e-169 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HHMJEDOE_02530 1.9e-62 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHMJEDOE_02531 5.4e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HHMJEDOE_02532 3e-235 EGP Major facilitator superfamily
HHMJEDOE_02533 5.8e-158 yyaK S CAAX protease self-immunity
HHMJEDOE_02534 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HHMJEDOE_02535 4.8e-34 V HNH nucleases
HHMJEDOE_02536 2.9e-90 3.6.3.55 P tungstate ion transport
HHMJEDOE_02537 8.9e-41 S Abortive infection C-terminus
HHMJEDOE_02538 9.8e-52 L Restriction endonuclease
HHMJEDOE_02539 8.4e-64 ynaF
HHMJEDOE_02540 1.9e-67
HHMJEDOE_02541 2.5e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HHMJEDOE_02542 7e-80 yosT L Bacterial transcription activator, effector binding domain
HHMJEDOE_02543 1.4e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HHMJEDOE_02544 1.2e-79 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HHMJEDOE_02545 3e-155 1.1.1.219 M NAD dependent epimerase dehydratase family
HHMJEDOE_02546 1.1e-16 yyaL O Highly conserved protein containing a thioredoxin domain
HHMJEDOE_02547 9.4e-156 yyaM EG EamA-like transporter family
HHMJEDOE_02548 1.9e-60 yyaN K MerR HTH family regulatory protein
HHMJEDOE_02549 1e-89 yyaS S Membrane
HHMJEDOE_02550 8.2e-62 yjcF S Acetyltransferase (GNAT) domain
HHMJEDOE_02551 1.1e-72 yybA 2.3.1.57 K transcriptional
HHMJEDOE_02552 2.3e-119 S Metallo-beta-lactamase superfamily
HHMJEDOE_02553 3.5e-142 bla 3.5.2.6 V beta-lactamase
HHMJEDOE_02554 1.4e-110 yybG S Pentapeptide repeat-containing protein
HHMJEDOE_02555 5.4e-60 yybH S SnoaL-like domain
HHMJEDOE_02556 2.1e-119
HHMJEDOE_02557 4.1e-237 yybO G COG0477 Permeases of the major facilitator superfamily
HHMJEDOE_02559 6.1e-68
HHMJEDOE_02560 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HHMJEDOE_02561 3e-68 ydeP3 K Transcriptional regulator
HHMJEDOE_02562 2.7e-77 cotF M Spore coat protein
HHMJEDOE_02564 8.4e-152 yybS S membrane
HHMJEDOE_02565 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHMJEDOE_02566 7.1e-72 rplI J binds to the 23S rRNA
HHMJEDOE_02567 1.2e-304 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHMJEDOE_02568 1.8e-194 yeaN P COG2807 Cyanate permease
HHMJEDOE_02569 1.8e-13 yycC K YycC-like protein
HHMJEDOE_02571 2.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HHMJEDOE_02572 6.8e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHMJEDOE_02573 1.2e-68 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHMJEDOE_02574 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHMJEDOE_02579 3.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_02580 0.0 vicK 2.7.13.3 T Histidine kinase
HHMJEDOE_02581 8.3e-249 yycH S protein conserved in bacteria
HHMJEDOE_02582 1e-148 yycI S protein conserved in bacteria
HHMJEDOE_02583 1.6e-148 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HHMJEDOE_02584 9.3e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHMJEDOE_02585 1.1e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HHMJEDOE_02586 8.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HHMJEDOE_02587 2.1e-258 rocE E amino acid
HHMJEDOE_02588 2.6e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HHMJEDOE_02590 8.5e-188 S aspartate phosphatase
HHMJEDOE_02591 6.2e-79 yycN 2.3.1.128 K Acetyltransferase
HHMJEDOE_02592 2e-124 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHMJEDOE_02593 1.1e-196 yycP
HHMJEDOE_02596 7.4e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHMJEDOE_02597 2.3e-61
HHMJEDOE_02598 1.1e-09 S YyzF-like protein
HHMJEDOE_02599 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHMJEDOE_02600 6.9e-156 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HHMJEDOE_02601 3.3e-13 U Protein of unknown function DUF262
HHMJEDOE_02605 2.6e-134 S MvaI/BcnI restriction endonuclease family
HHMJEDOE_02606 6.2e-22 3.1.3.16 S Protein of unknown function (DUF1643)
HHMJEDOE_02607 6.9e-15
HHMJEDOE_02609 4.6e-81 S Phage plasmid primase, P4 family
HHMJEDOE_02610 1.3e-28 L Recombinase
HHMJEDOE_02611 1.1e-40 L Recombinase
HHMJEDOE_02612 6.3e-32 K Helix-turn-helix XRE-family like proteins
HHMJEDOE_02613 3e-36
HHMJEDOE_02614 1e-127 V ATPases associated with a variety of cellular activities
HHMJEDOE_02615 9.2e-98
HHMJEDOE_02616 1.9e-154 ydjC S Abhydrolase domain containing 18
HHMJEDOE_02617 3.8e-68 prsK T PFAM ATP-binding region ATPase domain protein
HHMJEDOE_02618 4.8e-41 T cheY-homologous receiver domain
HHMJEDOE_02619 1.1e-08 S Lantibiotic alpha
HHMJEDOE_02621 8.7e-179 lanM V type 2 lantibiotic biosynthesis protein LanM
HHMJEDOE_02622 4.1e-141 3.6.3.27 V ABC transporter
HHMJEDOE_02623 5.6e-167 lanM V Lanthionine synthetase C family protein
HHMJEDOE_02624 1.1e-70 1.6.5.5 C alcohol dehydrogenase
HHMJEDOE_02625 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HHMJEDOE_02626 3.9e-11
HHMJEDOE_02627 8.3e-179 S Radical SAM superfamily
HHMJEDOE_02628 8.7e-131 yydH O Peptidase M50
HHMJEDOE_02629 4.7e-106 prrC P ABC transporter
HHMJEDOE_02630 2.6e-116 S ABC-2 family transporter protein
HHMJEDOE_02631 8.4e-12
HHMJEDOE_02632 4.3e-18
HHMJEDOE_02633 4.3e-189 wgaE S Polysaccharide pyruvyl transferase
HHMJEDOE_02634 8.3e-282 ahpF O Alkyl hydroperoxide reductase
HHMJEDOE_02635 5.1e-104 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HHMJEDOE_02637 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHMJEDOE_02638 3.6e-228 gntP EG COG2610 H gluconate symporter and related permeases
HHMJEDOE_02639 2.7e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HHMJEDOE_02640 2.2e-123 gntR K transcriptional
HHMJEDOE_02641 7.3e-190 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHMJEDOE_02642 5e-190 yxaB GM Polysaccharide pyruvyl transferase
HHMJEDOE_02643 6.7e-210 nhaS2 P Sodium/hydrogen exchanger family
HHMJEDOE_02644 1.1e-113 yxaC M effector of murein hydrolase
HHMJEDOE_02645 1.3e-45 S LrgA family
HHMJEDOE_02646 1.4e-65 yxaD K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_02647 8.1e-183 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_02648 8.1e-97 yxaF K Transcriptional regulator
HHMJEDOE_02649 3.4e-183 yxaG 1.13.11.24 S AraC-like ligand binding domain
HHMJEDOE_02650 3.7e-208 P Protein of unknown function (DUF418)
HHMJEDOE_02651 5.8e-74 yxaI S membrane protein domain
HHMJEDOE_02652 1.9e-58 S Family of unknown function (DUF5391)
HHMJEDOE_02653 5.1e-80 S PQQ-like domain
HHMJEDOE_02654 6.2e-18 yxaI S membrane protein domain
HHMJEDOE_02655 1.1e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HHMJEDOE_02656 2.1e-176 yxbF K Bacterial regulatory proteins, tetR family
HHMJEDOE_02659 1.8e-145 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_02661 0.0 htpG O Molecular chaperone. Has ATPase activity
HHMJEDOE_02662 1.7e-238 csbC EGP Major facilitator Superfamily
HHMJEDOE_02663 6.8e-79 T HPP family
HHMJEDOE_02664 1.7e-91 S CGNR zinc finger
HHMJEDOE_02665 5.7e-49 yxcD S Protein of unknown function (DUF2653)
HHMJEDOE_02667 1.9e-172 iolS C Aldo keto reductase
HHMJEDOE_02668 1.2e-137 iolR K COG1349 Transcriptional regulators of sugar metabolism
HHMJEDOE_02669 3.7e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHMJEDOE_02670 4.4e-149 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HHMJEDOE_02671 6.7e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HHMJEDOE_02672 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HHMJEDOE_02673 1.2e-168 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HHMJEDOE_02674 4.4e-231 iolF EGP Major facilitator Superfamily
HHMJEDOE_02675 8.9e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HHMJEDOE_02676 7.3e-166 iolH G Xylose isomerase-like TIM barrel
HHMJEDOE_02677 1.4e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HHMJEDOE_02678 7.6e-139 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HHMJEDOE_02679 3.5e-169 fhuD P ABC transporter
HHMJEDOE_02680 3.1e-10
HHMJEDOE_02681 2.7e-47
HHMJEDOE_02682 1e-12 yxeD
HHMJEDOE_02686 7.8e-146 yidA S hydrolases of the HAD superfamily
HHMJEDOE_02687 7.3e-250 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHMJEDOE_02688 3.9e-87 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_02689 1.9e-128 yxeM M Belongs to the bacterial solute-binding protein 3 family
HHMJEDOE_02690 8.6e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
HHMJEDOE_02691 2.5e-130 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HHMJEDOE_02692 2.7e-208 yxeP 3.5.1.47 E hydrolase activity
HHMJEDOE_02693 1e-235 yxeQ S MmgE/PrpD family
HHMJEDOE_02694 1.9e-187 eutH E Ethanolamine utilisation protein, EutH
HHMJEDOE_02695 3.7e-143 yxxB S Domain of Unknown Function (DUF1206)
HHMJEDOE_02696 5.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHMJEDOE_02697 3.2e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHMJEDOE_02698 3.9e-194 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHMJEDOE_02699 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HHMJEDOE_02700 1.9e-251 lysP E amino acid
HHMJEDOE_02701 4e-173 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HHMJEDOE_02702 3.3e-228 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HHMJEDOE_02703 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HHMJEDOE_02704 1.2e-277 hutH 4.3.1.3 E Histidine ammonia-lyase
HHMJEDOE_02705 9.6e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HHMJEDOE_02706 5e-273 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HHMJEDOE_02707 2.1e-21 S Domain of unknown function (DUF5082)
HHMJEDOE_02708 2e-37 yxiC S Family of unknown function (DUF5344)
HHMJEDOE_02709 2.8e-197 S nuclease activity
HHMJEDOE_02710 6.8e-44
HHMJEDOE_02711 3e-45
HHMJEDOE_02714 3.3e-33 S Uncharacterized protein conserved in bacteria (DUF2247)
HHMJEDOE_02715 1.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_02716 8.8e-270 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHMJEDOE_02717 1.2e-68 yxiE T Belongs to the universal stress protein A family
HHMJEDOE_02718 2.7e-121 1.14.11.45 E 2OG-Fe dioxygenase
HHMJEDOE_02719 6.3e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_02720 7.3e-156 yxxF EG EamA-like transporter family
HHMJEDOE_02722 4.1e-33
HHMJEDOE_02723 2.7e-36
HHMJEDOE_02724 7.4e-68 yxiG
HHMJEDOE_02725 1.2e-136
HHMJEDOE_02726 7.9e-93 yxiI S Protein of unknown function (DUF2716)
HHMJEDOE_02727 3.3e-37 yxiJ S YxiJ-like protein
HHMJEDOE_02730 4.5e-34 yxxF EG EamA-like transporter family
HHMJEDOE_02732 6.5e-43 S Protein of unknown function (DUF2812)
HHMJEDOE_02733 1.5e-50 padR K Transcriptional regulator PadR-like family
HHMJEDOE_02734 2.6e-203 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_02735 1.6e-258 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HHMJEDOE_02736 1e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
HHMJEDOE_02737 1e-90
HHMJEDOE_02738 1.9e-147 licT K transcriptional antiterminator
HHMJEDOE_02739 1e-241 bglF G phosphotransferase system
HHMJEDOE_02740 9.2e-259 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHMJEDOE_02741 4e-161
HHMJEDOE_02742 3.2e-218 citH C Citrate transporter
HHMJEDOE_02743 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HHMJEDOE_02744 9.3e-44 yxiS
HHMJEDOE_02745 7.7e-107 T Domain of unknown function (DUF4163)
HHMJEDOE_02746 2.7e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHMJEDOE_02747 2.9e-143 rlmA 2.1.1.187 Q Methyltransferase domain
HHMJEDOE_02748 8.6e-241 yxjC EG COG2610 H gluconate symporter and related permeases
HHMJEDOE_02749 5.1e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HHMJEDOE_02750 6e-112 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HHMJEDOE_02751 1.3e-129 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HHMJEDOE_02752 1.9e-214 yxjG 2.1.1.14 E Methionine synthase
HHMJEDOE_02753 1.6e-213 yxjG 2.1.1.14 E Methionine synthase
HHMJEDOE_02754 1.3e-66 yxjI S LURP-one-related
HHMJEDOE_02756 1e-226 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHMJEDOE_02757 6.2e-109 K helix_turn_helix, Lux Regulon
HHMJEDOE_02758 5.1e-165 yxjM T Signal transduction histidine kinase
HHMJEDOE_02759 1.1e-75 S Protein of unknown function (DUF1453)
HHMJEDOE_02760 8.1e-157 yxjO K LysR substrate binding domain
HHMJEDOE_02761 4.3e-86 yxkA S Phosphatidylethanolamine-binding protein
HHMJEDOE_02762 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHMJEDOE_02763 2.3e-76 yxkC S Domain of unknown function (DUF4352)
HHMJEDOE_02764 1.4e-145 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHMJEDOE_02765 1.7e-260 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHMJEDOE_02766 3e-146 lrp QT PucR C-terminal helix-turn-helix domain
HHMJEDOE_02767 2.7e-202 msmK P Belongs to the ABC transporter superfamily
HHMJEDOE_02768 2.8e-110 P transporter
HHMJEDOE_02769 6.6e-148 yxkH G Polysaccharide deacetylase
HHMJEDOE_02771 4.7e-286 3.4.24.84 O Peptidase family M48
HHMJEDOE_02772 2.4e-224 cimH C COG3493 Na citrate symporter
HHMJEDOE_02773 1.3e-265 cydA 1.10.3.14 C oxidase, subunit
HHMJEDOE_02774 1.9e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HHMJEDOE_02775 7.3e-303 cydD V ATP-binding
HHMJEDOE_02776 8.4e-307 cydD V ATP-binding protein
HHMJEDOE_02777 7e-150 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHMJEDOE_02778 2.8e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HHMJEDOE_02779 5.4e-87 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_02780 4e-37 yxlC S Family of unknown function (DUF5345)
HHMJEDOE_02781 3.2e-27
HHMJEDOE_02782 2.9e-27 yxlE S Phospholipase_D-nuclease N-terminal
HHMJEDOE_02783 2.9e-154 yxlF V ABC transporter, ATP-binding protein
HHMJEDOE_02784 5.4e-128 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHMJEDOE_02785 6.2e-200 yxlH EGP Major facilitator Superfamily
HHMJEDOE_02786 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HHMJEDOE_02787 4e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHMJEDOE_02788 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HHMJEDOE_02789 5.2e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HHMJEDOE_02790 1.6e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHMJEDOE_02791 7.4e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHMJEDOE_02792 5.6e-250 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHMJEDOE_02793 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HHMJEDOE_02794 3.5e-132 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_02795 2.9e-226 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHMJEDOE_02796 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_02797 2.2e-229 dltB M membrane protein involved in D-alanine export
HHMJEDOE_02798 2.2e-279 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_02799 1.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HHMJEDOE_02800 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HHMJEDOE_02801 5.8e-129 ynfM EGP Major facilitator Superfamily
HHMJEDOE_02802 1.4e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HHMJEDOE_02803 1.6e-93 K Helix-turn-helix XRE-family like proteins
HHMJEDOE_02804 1.3e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HHMJEDOE_02805 3.8e-216 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHMJEDOE_02806 1.2e-78 ywaE K Transcriptional regulator
HHMJEDOE_02807 1.1e-114 ywaF S Integral membrane protein
HHMJEDOE_02808 9.1e-161 gspA M General stress
HHMJEDOE_02809 1.6e-149 sacY K transcriptional antiterminator
HHMJEDOE_02810 4.2e-231 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_02811 3.1e-257 epr 3.4.21.62 O Belongs to the peptidase S8 family
HHMJEDOE_02812 3.6e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHMJEDOE_02813 2.2e-66 ywbC 4.4.1.5 E glyoxalase
HHMJEDOE_02814 5.4e-212 ywbD 2.1.1.191 J Methyltransferase
HHMJEDOE_02815 4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HHMJEDOE_02816 6.2e-208 ywbF EGP Major facilitator Superfamily
HHMJEDOE_02817 1.2e-125
HHMJEDOE_02820 3.7e-98 V ATPases associated with a variety of cellular activities
HHMJEDOE_02821 6.4e-109 ywbG M effector of murein hydrolase
HHMJEDOE_02822 5.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HHMJEDOE_02823 1.2e-150 ywbI K Transcriptional regulator
HHMJEDOE_02824 1.9e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHMJEDOE_02825 1.2e-107 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHMJEDOE_02826 5.5e-243 P COG0672 High-affinity Fe2 Pb2 permease
HHMJEDOE_02827 1.4e-156 ycdO P periplasmic lipoprotein involved in iron transport
HHMJEDOE_02828 1.4e-218 ywbN P Dyp-type peroxidase family protein
HHMJEDOE_02829 9.1e-107 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HHMJEDOE_02830 2.4e-265 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHMJEDOE_02831 6.6e-45 ywcB S Protein of unknown function, DUF485
HHMJEDOE_02833 7.5e-102 ywcC K transcriptional regulator
HHMJEDOE_02834 1.4e-58 gtcA S GtrA-like protein
HHMJEDOE_02835 2.5e-217 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHMJEDOE_02836 7.1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHMJEDOE_02837 2.2e-35 ywzA S membrane
HHMJEDOE_02838 4e-176 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HHMJEDOE_02839 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HHMJEDOE_02840 3.6e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HHMJEDOE_02841 4.5e-59 qoxD 1.10.3.12 C quinol oxidase, subunit
HHMJEDOE_02842 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HHMJEDOE_02843 6.4e-189 rodA D Belongs to the SEDS family
HHMJEDOE_02844 7.7e-132 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HHMJEDOE_02845 1.8e-176 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHMJEDOE_02846 3.2e-53 L COG2963 Transposase and inactivated derivatives
HHMJEDOE_02847 9.4e-161 ygxA S Nucleotidyltransferase-like
HHMJEDOE_02848 8.1e-55 ygzB S UPF0295 protein
HHMJEDOE_02849 4e-80 perR P Belongs to the Fur family
HHMJEDOE_02850 1.2e-85 bcp 1.11.1.15 O Peroxiredoxin
HHMJEDOE_02851 5.4e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HHMJEDOE_02852 8.1e-178 ygaE S Membrane
HHMJEDOE_02853 3.3e-295 ygaD V ABC transporter
HHMJEDOE_02854 3.7e-104 ygaC J Belongs to the UPF0374 family
HHMJEDOE_02855 5.6e-37 ygaB S YgaB-like protein
HHMJEDOE_02856 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HHMJEDOE_02857 6.4e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_02858 2e-35 yfhS
HHMJEDOE_02859 7.8e-205 mutY L A G-specific
HHMJEDOE_02860 9.7e-183 yfhP S membrane-bound metal-dependent
HHMJEDOE_02861 0.0 yfhO S Bacterial membrane protein YfhO
HHMJEDOE_02862 2.9e-179 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHMJEDOE_02863 1e-159 yfhM S Alpha beta hydrolase
HHMJEDOE_02864 1.6e-36 yfhL S SdpI/YhfL protein family
HHMJEDOE_02865 5.1e-82 batE T Bacterial SH3 domain homologues
HHMJEDOE_02866 1.6e-42 yfhJ S WVELL protein
HHMJEDOE_02867 1.4e-19 sspK S reproduction
HHMJEDOE_02868 5.8e-206 yfhI EGP Major facilitator Superfamily
HHMJEDOE_02869 2.4e-45 yfhH S Protein of unknown function (DUF1811)
HHMJEDOE_02870 2.3e-134 recX 2.4.1.337 GT4 S Modulates RecA activity
HHMJEDOE_02871 1.8e-162 yfhF S nucleoside-diphosphate sugar epimerase
HHMJEDOE_02873 5.2e-24 yfhD S YfhD-like protein
HHMJEDOE_02874 1.3e-102 yfhC C nitroreductase
HHMJEDOE_02875 1.2e-152 yfhB 5.3.3.17 S PhzF family
HHMJEDOE_02876 4.3e-173 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_02877 1.8e-168 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_02878 8.2e-174 yfiY P ABC transporter substrate-binding protein
HHMJEDOE_02879 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHMJEDOE_02880 4.1e-78 yfiV K transcriptional
HHMJEDOE_02881 2.5e-278 yfiU EGP Major facilitator Superfamily
HHMJEDOE_02882 5.6e-92 yfiT S Belongs to the metal hydrolase YfiT family
HHMJEDOE_02883 1.5e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HHMJEDOE_02884 6.2e-74 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHMJEDOE_02885 1.4e-93 padR K transcriptional
HHMJEDOE_02886 2.7e-69 J Acetyltransferase (GNAT) domain
HHMJEDOE_02887 2.5e-185 V COG0842 ABC-type multidrug transport system, permease component
HHMJEDOE_02888 6.9e-191 V ABC-2 family transporter protein
HHMJEDOE_02889 1.5e-164 V ABC transporter, ATP-binding protein
HHMJEDOE_02890 5.8e-107 KT LuxR family transcriptional regulator
HHMJEDOE_02891 4.1e-201 yxjM T Histidine kinase
HHMJEDOE_02893 1.6e-152 yfiE 1.13.11.2 S glyoxalase
HHMJEDOE_02894 1.1e-60 mhqP S DoxX
HHMJEDOE_02895 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HHMJEDOE_02896 3.5e-297 yfiB3 V ABC transporter
HHMJEDOE_02897 1.1e-289 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_02898 4.3e-138 glvR K Helix-turn-helix domain, rpiR family
HHMJEDOE_02899 2.5e-258 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HHMJEDOE_02900 1.4e-42 yfjA S Belongs to the WXG100 family
HHMJEDOE_02901 5.4e-183 yfjB
HHMJEDOE_02902 5.5e-141 yfjC
HHMJEDOE_02903 4.9e-99 yfjD S Family of unknown function (DUF5381)
HHMJEDOE_02904 7.7e-81 S Family of unknown function (DUF5381)
HHMJEDOE_02905 1.7e-54 yfjF S UPF0060 membrane protein
HHMJEDOE_02906 1.1e-23 sspH S Belongs to the SspH family
HHMJEDOE_02907 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HHMJEDOE_02908 1.9e-248 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HHMJEDOE_02909 7.9e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHMJEDOE_02910 1.8e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HHMJEDOE_02911 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HHMJEDOE_02912 4.6e-30 yfjL
HHMJEDOE_02913 2.4e-80 yfjM S Psort location Cytoplasmic, score
HHMJEDOE_02914 9.1e-75 ydaF_2 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHMJEDOE_02915 7.9e-185 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHMJEDOE_02916 6.9e-165 D nuclear chromosome segregation
HHMJEDOE_02917 7e-77
HHMJEDOE_02918 7.9e-39 S FRG domain
HHMJEDOE_02919 4.5e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHMJEDOE_02920 8.6e-159 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HHMJEDOE_02921 3.4e-180 corA P Mediates influx of magnesium ions
HHMJEDOE_02922 1.9e-142 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HHMJEDOE_02923 4.2e-152 pdaA G deacetylase
HHMJEDOE_02924 1.1e-26 yfjT
HHMJEDOE_02925 3.4e-216 yfkA S YfkB-like domain
HHMJEDOE_02926 4.3e-147 yfkC M Mechanosensitive ion channel
HHMJEDOE_02927 1.6e-143 yfkD S YfkD-like protein
HHMJEDOE_02928 5.9e-178 cax P COG0387 Ca2 H antiporter
HHMJEDOE_02929 1.5e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HHMJEDOE_02931 3.5e-141 yihY S Belongs to the UPF0761 family
HHMJEDOE_02932 6e-49 yfkI S gas vesicle protein
HHMJEDOE_02933 1.3e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHMJEDOE_02934 3e-28 yfkK S Belongs to the UPF0435 family
HHMJEDOE_02935 2.4e-196 ydiM EGP Major facilitator Superfamily
HHMJEDOE_02936 6.2e-88 yfkM 3.5.1.124 S protease
HHMJEDOE_02937 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HHMJEDOE_02938 5.8e-123 yfkO C nitroreductase
HHMJEDOE_02939 5.3e-130 treR K transcriptional
HHMJEDOE_02940 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HHMJEDOE_02941 1.7e-252 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_02942 8.4e-274 yfkQ EG Spore germination protein
HHMJEDOE_02943 5.3e-188 yfkR S spore germination
HHMJEDOE_02945 8.4e-180 E Spore germination protein
HHMJEDOE_02946 8.9e-246 agcS_1 E Sodium alanine symporter
HHMJEDOE_02947 5.2e-63 yhdN S Domain of unknown function (DUF1992)
HHMJEDOE_02948 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHMJEDOE_02949 4.5e-247 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HHMJEDOE_02950 1.6e-137 map 3.4.11.18 E Methionine aminopeptidase
HHMJEDOE_02951 4.7e-46 yflH S Protein of unknown function (DUF3243)
HHMJEDOE_02952 1e-17 yflI
HHMJEDOE_02953 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HHMJEDOE_02954 1.9e-113 yflK S protein conserved in bacteria
HHMJEDOE_02955 2.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHMJEDOE_02956 3.7e-208 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HHMJEDOE_02957 2e-146 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HHMJEDOE_02958 1.2e-225 citM C Citrate transporter
HHMJEDOE_02959 5.2e-165 yflP S Tripartite tricarboxylate transporter family receptor
HHMJEDOE_02960 8.1e-112 citT T response regulator
HHMJEDOE_02961 2.8e-267 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHMJEDOE_02962 1.5e-232 yflS P Sodium:sulfate symporter transmembrane region
HHMJEDOE_02963 5.3e-234 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HHMJEDOE_02964 9.3e-56 yflT S Heat induced stress protein YflT
HHMJEDOE_02965 6.9e-25 S Protein of unknown function (DUF3212)
HHMJEDOE_02966 2.9e-160 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HHMJEDOE_02967 1.9e-165 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_02968 8.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_02969 1.7e-148 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HHMJEDOE_02970 3.2e-181 yfmJ S N-terminal domain of oxidoreductase
HHMJEDOE_02971 1.4e-67 yfmK 2.3.1.128 K acetyltransferase
HHMJEDOE_02972 3.6e-197 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HHMJEDOE_02973 1.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHMJEDOE_02974 6.3e-73
HHMJEDOE_02975 8.9e-207 yfmO EGP Major facilitator Superfamily
HHMJEDOE_02976 2.8e-70 yfmP K transcriptional
HHMJEDOE_02977 1e-67 yfmQ S Uncharacterised protein from bacillus cereus group
HHMJEDOE_02978 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HHMJEDOE_02979 1.7e-111 yfmS NT chemotaxis protein
HHMJEDOE_02980 1e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHMJEDOE_02981 6.7e-238 yfnA E amino acid
HHMJEDOE_02982 4.9e-120 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHMJEDOE_02983 4.7e-203 fsr P COG0477 Permeases of the major facilitator superfamily
HHMJEDOE_02984 1.8e-186 yfnD M Nucleotide-diphospho-sugar transferase
HHMJEDOE_02985 8.7e-215 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HHMJEDOE_02986 1.6e-176 yfnF M Nucleotide-diphospho-sugar transferase
HHMJEDOE_02987 1.6e-171 yfnG 4.2.1.45 M dehydratase
HHMJEDOE_02988 6.2e-145 rfbF 2.7.7.33 JM Nucleotidyl transferase
HHMJEDOE_02989 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHMJEDOE_02990 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HHMJEDOE_02991 1.5e-197 yetN S Protein of unknown function (DUF3900)
HHMJEDOE_02992 5e-204 yetM CH FAD binding domain
HHMJEDOE_02993 1.2e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_02994 2.5e-156 yetK EG EamA-like transporter family
HHMJEDOE_02995 9.1e-105 yetJ S Belongs to the BI1 family
HHMJEDOE_02996 2.6e-19 yezD S Uncharacterized small protein (DUF2292)
HHMJEDOE_02997 6.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HHMJEDOE_02998 1.5e-36
HHMJEDOE_02999 1.3e-60 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHMJEDOE_03000 5.5e-50 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HHMJEDOE_03001 4e-106 yetF S membrane
HHMJEDOE_03002 1.2e-231 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HHMJEDOE_03003 4.7e-160 lplC G Binding-protein-dependent transport system inner membrane component
HHMJEDOE_03004 4.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HHMJEDOE_03005 4e-284 lplA G Bacterial extracellular solute-binding protein
HHMJEDOE_03006 0.0 yetA
HHMJEDOE_03007 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HHMJEDOE_03008 6.3e-122 yesY E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_03009 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HHMJEDOE_03010 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HHMJEDOE_03011 2.5e-107 yesV S Protein of unknown function, DUF624
HHMJEDOE_03012 6.2e-125 yesU S Domain of unknown function (DUF1961)
HHMJEDOE_03013 1.3e-102 E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_03014 3.5e-11 E GDSL-like Lipase/Acylhydrolase
HHMJEDOE_03015 0.0 yesS K Transcriptional regulator
HHMJEDOE_03016 3.4e-194 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HHMJEDOE_03017 6.1e-160 yesQ P Binding-protein-dependent transport system inner membrane component
HHMJEDOE_03018 4e-170 yesP G Binding-protein-dependent transport system inner membrane component
HHMJEDOE_03019 1.3e-240 yesO G Bacterial extracellular solute-binding protein
HHMJEDOE_03020 8e-194 yesN K helix_turn_helix, arabinose operon control protein
HHMJEDOE_03021 7.9e-297 yesM 2.7.13.3 T Histidine kinase
HHMJEDOE_03022 1.8e-94 yesL S Protein of unknown function, DUF624
HHMJEDOE_03024 5.3e-90 yesJ K Acetyltransferase (GNAT) family
HHMJEDOE_03025 3.4e-103 cotJC P Spore Coat
HHMJEDOE_03026 4.3e-45 cotJB S CotJB protein
HHMJEDOE_03027 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HHMJEDOE_03028 2.5e-142 yesF GM NAD(P)H-binding
HHMJEDOE_03029 2.2e-78 yesE S SnoaL-like domain
HHMJEDOE_03030 1.2e-95 dhaR3 K Transcriptional regulator
HHMJEDOE_03032 2e-124 yeeN K transcriptional regulatory protein
HHMJEDOE_03034 1.1e-177 S Tetratricopeptide repeat
HHMJEDOE_03035 3.3e-49
HHMJEDOE_03036 9.6e-100 L endonuclease activity
HHMJEDOE_03038 0.0 L nucleic acid phosphodiester bond hydrolysis
HHMJEDOE_03039 3.6e-50 S Protein of unknown function, DUF600
HHMJEDOE_03040 6.3e-52 S Protein of unknown function, DUF600
HHMJEDOE_03041 1.3e-83 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HHMJEDOE_03042 0.0 2.1.1.72, 3.1.21.4 L DEAD-like helicases superfamily
HHMJEDOE_03043 2.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHMJEDOE_03044 8.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HHMJEDOE_03045 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HHMJEDOE_03046 4.3e-139 yerO K Transcriptional regulator
HHMJEDOE_03047 2.6e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHMJEDOE_03048 1.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHMJEDOE_03049 2.8e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHMJEDOE_03050 1.3e-260 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHMJEDOE_03051 1.5e-121 sapB S MgtC SapB transporter
HHMJEDOE_03052 1.2e-183 yerI S homoserine kinase type II (protein kinase fold)
HHMJEDOE_03053 3.3e-217 camS S COG4851 Protein involved in sex pheromone biosynthesis
HHMJEDOE_03054 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHMJEDOE_03055 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHMJEDOE_03056 8.7e-122 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HHMJEDOE_03057 2.2e-290 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HHMJEDOE_03058 4.8e-51 yerC S protein conserved in bacteria
HHMJEDOE_03059 8e-185 yerB S Protein of unknown function (DUF3048) C-terminal domain
HHMJEDOE_03060 0.0 yerA 3.5.4.2 F adenine deaminase
HHMJEDOE_03061 5.9e-30 S Protein of unknown function (DUF2892)
HHMJEDOE_03062 1.1e-210 yjeH E Amino acid permease
HHMJEDOE_03063 4e-69 K helix_turn_helix ASNC type
HHMJEDOE_03064 4.4e-228 purD 6.3.4.13 F Belongs to the GARS family
HHMJEDOE_03065 6.8e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HHMJEDOE_03066 5.5e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HHMJEDOE_03067 1.9e-173 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HHMJEDOE_03068 2.8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HHMJEDOE_03069 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHMJEDOE_03070 2.8e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHMJEDOE_03071 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HHMJEDOE_03072 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HHMJEDOE_03073 1.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHMJEDOE_03074 7.7e-208 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHMJEDOE_03075 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HHMJEDOE_03076 1.4e-27 yebG S NETI protein
HHMJEDOE_03077 4e-93 yebE S UPF0316 protein
HHMJEDOE_03079 4e-110 yebC M Membrane
HHMJEDOE_03080 3.3e-210 pbuG S permease
HHMJEDOE_03081 1.2e-245 S Domain of unknown function (DUF4179)
HHMJEDOE_03082 7.3e-84 K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_03083 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHMJEDOE_03084 0.0 yebA E COG1305 Transglutaminase-like enzymes
HHMJEDOE_03085 2.7e-203 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HHMJEDOE_03086 8.6e-168 yeaC S COG0714 MoxR-like ATPases
HHMJEDOE_03087 1.1e-148 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHMJEDOE_03088 1.5e-248 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_03089 2.1e-309 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HHMJEDOE_03090 4.7e-153 yeaA S Protein of unknown function (DUF4003)
HHMJEDOE_03091 1.9e-147 ydjP I Alpha/beta hydrolase family
HHMJEDOE_03092 1.2e-34 ydjO S Cold-inducible protein YdjO
HHMJEDOE_03093 4.8e-61 yusQ S Tautomerase enzyme
HHMJEDOE_03094 2.6e-111 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_03095 3.7e-149 yusT K LysR substrate binding domain
HHMJEDOE_03096 1.4e-37 yusU S Protein of unknown function (DUF2573)
HHMJEDOE_03097 2.6e-152 yusV 3.6.3.34 HP ABC transporter
HHMJEDOE_03098 1.3e-67 S YusW-like protein
HHMJEDOE_03099 2.7e-303 pepF2 E COG1164 Oligoendopeptidase F
HHMJEDOE_03100 1.6e-146 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_03101 5.2e-78 dps P Ferritin-like domain
HHMJEDOE_03102 5.1e-222 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHMJEDOE_03103 3.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_03104 9.4e-245 cssS 2.7.13.3 T PhoQ Sensor
HHMJEDOE_03105 1.7e-23
HHMJEDOE_03106 8.4e-154 yuxN K Transcriptional regulator
HHMJEDOE_03107 1.1e-259 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHMJEDOE_03108 3.9e-24 S Protein of unknown function (DUF3970)
HHMJEDOE_03109 2e-237 gerAA EG Spore germination protein
HHMJEDOE_03110 5.5e-179 gerAB E Spore germination protein
HHMJEDOE_03111 1.8e-172 gerAC S Spore germination B3/ GerAC like, C-terminal
HHMJEDOE_03112 2.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_03113 7.4e-184 vraS 2.7.13.3 T Histidine kinase
HHMJEDOE_03114 2e-121 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HHMJEDOE_03115 3e-95 liaG S Putative adhesin
HHMJEDOE_03116 1.1e-97 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HHMJEDOE_03117 1.6e-61 liaI S membrane
HHMJEDOE_03118 5e-224 yvqJ EGP Major facilitator Superfamily
HHMJEDOE_03119 9.4e-93 yvqK 2.5.1.17 S Adenosyltransferase
HHMJEDOE_03120 2.8e-217 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HHMJEDOE_03121 3.8e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03122 2.2e-163 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HHMJEDOE_03123 6.5e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_03124 2.7e-160 yvrE G SMP-30/Gluconolaconase/LRE-like region
HHMJEDOE_03125 1.3e-307 T PhoQ Sensor
HHMJEDOE_03126 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_03127 5.8e-25
HHMJEDOE_03128 1.9e-98 yvrI K RNA polymerase
HHMJEDOE_03129 5e-17 S YvrJ protein family
HHMJEDOE_03130 3.4e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HHMJEDOE_03131 2.5e-47 yvrL S Regulatory protein YrvL
HHMJEDOE_03132 5.2e-194 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HHMJEDOE_03133 1.1e-121 macB V ABC transporter, ATP-binding protein
HHMJEDOE_03134 1.7e-168 M Efflux transporter rnd family, mfp subunit
HHMJEDOE_03135 6.6e-145 fhuC 3.6.3.34 HP ABC transporter
HHMJEDOE_03136 1.8e-171 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03137 2e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03138 5e-160 fhuD P ABC transporter
HHMJEDOE_03140 4.7e-231 yvsH E Arginine ornithine antiporter
HHMJEDOE_03141 1.5e-15 S Small spore protein J (Spore_SspJ)
HHMJEDOE_03142 1.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HHMJEDOE_03143 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HHMJEDOE_03144 1e-157 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HHMJEDOE_03145 9.9e-130 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HHMJEDOE_03146 1.3e-114 modB P COG4149 ABC-type molybdate transport system, permease component
HHMJEDOE_03147 3e-153 yvgN S reductase
HHMJEDOE_03148 5.1e-84 yvgO
HHMJEDOE_03149 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HHMJEDOE_03150 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HHMJEDOE_03151 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HHMJEDOE_03152 0.0 helD 3.6.4.12 L DNA helicase
HHMJEDOE_03153 1.3e-105 yvgT S membrane
HHMJEDOE_03154 4.2e-71 bdbC O Required for disulfide bond formation in some proteins
HHMJEDOE_03155 9.1e-100 bdbD O Thioredoxin
HHMJEDOE_03156 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HHMJEDOE_03157 0.0 copA 3.6.3.54 P P-type ATPase
HHMJEDOE_03158 1e-28 copZ P Copper resistance protein CopZ
HHMJEDOE_03159 2e-46 csoR S transcriptional
HHMJEDOE_03160 1.6e-180 yvaA 1.1.1.371 S Oxidoreductase
HHMJEDOE_03161 6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HHMJEDOE_03162 3e-136 exoK GH16 M licheninase activity
HHMJEDOE_03163 1.2e-67 yvaD S Family of unknown function (DUF5360)
HHMJEDOE_03164 2.3e-49 yvaE P Small Multidrug Resistance protein
HHMJEDOE_03165 1.2e-92 K Bacterial regulatory proteins, tetR family
HHMJEDOE_03166 3e-126 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_03168 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HHMJEDOE_03169 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHMJEDOE_03170 2.1e-142 est 3.1.1.1 S Carboxylesterase
HHMJEDOE_03171 2.4e-23 secG U Preprotein translocase subunit SecG
HHMJEDOE_03172 6.6e-134 yvaM S Serine aminopeptidase, S33
HHMJEDOE_03173 9.8e-36 yvzC K Transcriptional
HHMJEDOE_03174 4e-69 K transcriptional
HHMJEDOE_03175 6.4e-67 yvaO K Cro/C1-type HTH DNA-binding domain
HHMJEDOE_03176 4.8e-54 yodB K transcriptional
HHMJEDOE_03177 1e-179 NT chemotaxis protein
HHMJEDOE_03178 1.5e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHMJEDOE_03179 1.2e-163 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHMJEDOE_03180 1.2e-107 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHMJEDOE_03181 2.5e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHMJEDOE_03182 8.1e-83 yvbF K Belongs to the GbsR family
HHMJEDOE_03183 1.2e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHMJEDOE_03184 8.2e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHMJEDOE_03185 1.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HHMJEDOE_03186 8.5e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HHMJEDOE_03187 1.8e-93 yvbF K Belongs to the GbsR family
HHMJEDOE_03188 3.3e-99 yvbG U UPF0056 membrane protein
HHMJEDOE_03189 4.4e-109 yvbH S YvbH-like oligomerisation region
HHMJEDOE_03190 2.5e-116 exoY M Membrane
HHMJEDOE_03191 0.0 tcaA S response to antibiotic
HHMJEDOE_03192 2.8e-76 yvbK 3.1.3.25 K acetyltransferase
HHMJEDOE_03193 8.2e-171 EGP Major facilitator Superfamily
HHMJEDOE_03194 7.5e-153
HHMJEDOE_03195 1.7e-114 S GlcNAc-PI de-N-acetylase
HHMJEDOE_03196 3.2e-125 C WbqC-like protein family
HHMJEDOE_03197 2.9e-113 M Protein involved in cellulose biosynthesis
HHMJEDOE_03198 4.2e-159 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HHMJEDOE_03199 1.5e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
HHMJEDOE_03200 2.1e-161 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HHMJEDOE_03201 5.6e-218 1.1.1.136 M UDP binding domain
HHMJEDOE_03202 1.2e-172 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HHMJEDOE_03203 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHMJEDOE_03204 1.5e-294 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HHMJEDOE_03205 1.3e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHMJEDOE_03206 1.1e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHMJEDOE_03207 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHMJEDOE_03208 1.7e-182 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HHMJEDOE_03209 1.7e-249 araE EGP Major facilitator Superfamily
HHMJEDOE_03210 9e-198 araR K transcriptional
HHMJEDOE_03211 2.2e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHMJEDOE_03212 1.3e-151 yvbU K Transcriptional regulator
HHMJEDOE_03213 5.9e-150 yvbV EG EamA-like transporter family
HHMJEDOE_03214 4.2e-221 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_03215 7.8e-183 yvbX S Glycosyl hydrolase
HHMJEDOE_03216 3.6e-126 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHMJEDOE_03217 6.2e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HHMJEDOE_03218 1.1e-132 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HHMJEDOE_03219 9.7e-101 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_03220 9e-177 desK 2.7.13.3 T Histidine kinase
HHMJEDOE_03221 3.3e-127 yvfS V COG0842 ABC-type multidrug transport system, permease component
HHMJEDOE_03222 7.9e-147 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HHMJEDOE_03223 4.1e-147 rsbQ S Alpha/beta hydrolase family
HHMJEDOE_03224 2.7e-166 rsbU 3.1.3.3 T response regulator
HHMJEDOE_03225 2.8e-230 galA 3.2.1.89 G arabinogalactan
HHMJEDOE_03226 0.0 lacA 3.2.1.23 G beta-galactosidase
HHMJEDOE_03227 1.5e-147 ganQ P transport
HHMJEDOE_03228 8.7e-229 malC P COG1175 ABC-type sugar transport systems, permease components
HHMJEDOE_03229 1.5e-223 cycB G COG2182 Maltose-binding periplasmic proteins domains
HHMJEDOE_03230 3.3e-178 lacR K Transcriptional regulator
HHMJEDOE_03231 1.4e-114 yvfI K COG2186 Transcriptional regulators
HHMJEDOE_03232 5e-304 yvfH C L-lactate permease
HHMJEDOE_03233 1.5e-231 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HHMJEDOE_03234 1e-31 yvfG S YvfG protein
HHMJEDOE_03235 1.6e-182 yvfF GM Exopolysaccharide biosynthesis protein
HHMJEDOE_03236 2.7e-208 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HHMJEDOE_03237 1.2e-40 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HHMJEDOE_03238 4.5e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHMJEDOE_03239 5.6e-246 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_03240 7.1e-176 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HHMJEDOE_03241 8.6e-193 epsI GM pyruvyl transferase
HHMJEDOE_03242 1.2e-186 epsH GT2 S Glycosyltransferase like family 2
HHMJEDOE_03243 1.4e-201 epsG S EpsG family
HHMJEDOE_03244 1.7e-202 epsF GT4 M Glycosyl transferases group 1
HHMJEDOE_03245 6.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HHMJEDOE_03246 1.7e-202 epsD GT4 M Glycosyl transferase 4-like
HHMJEDOE_03247 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HHMJEDOE_03248 3.3e-113 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HHMJEDOE_03249 7.1e-119 ywqC M biosynthesis protein
HHMJEDOE_03250 1e-73 slr K transcriptional
HHMJEDOE_03251 5.9e-261 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HHMJEDOE_03253 1e-92 padC Q Phenolic acid decarboxylase
HHMJEDOE_03254 4e-75 MA20_18690 S Protein of unknown function (DUF3237)
HHMJEDOE_03255 7.8e-115 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHMJEDOE_03256 2.9e-230 pbpE V Beta-lactamase
HHMJEDOE_03257 3.4e-269 sacB 2.4.1.10 GH68 M levansucrase activity
HHMJEDOE_03258 7.1e-297 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HHMJEDOE_03259 2.2e-290 yveA E amino acid
HHMJEDOE_03260 8e-100 yvdT K Transcriptional regulator
HHMJEDOE_03261 6.9e-48 ykkC P Small Multidrug Resistance protein
HHMJEDOE_03262 1.5e-47 sugE P Small Multidrug Resistance protein
HHMJEDOE_03263 1.5e-89 yvdQ S Protein of unknown function (DUF3231)
HHMJEDOE_03265 9.3e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHMJEDOE_03266 3.1e-103 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HHMJEDOE_03267 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HHMJEDOE_03268 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HHMJEDOE_03269 3.7e-133 malA S Protein of unknown function (DUF1189)
HHMJEDOE_03270 1.8e-145 malD P transport
HHMJEDOE_03271 7.4e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HHMJEDOE_03272 2.1e-227 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HHMJEDOE_03273 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HHMJEDOE_03274 4.5e-169 yvdE K Transcriptional regulator
HHMJEDOE_03275 3.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HHMJEDOE_03276 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HHMJEDOE_03277 3.2e-284 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HHMJEDOE_03278 9.4e-101 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HHMJEDOE_03279 5.8e-180 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHMJEDOE_03280 0.0 V ABC transporter (permease)
HHMJEDOE_03281 4.1e-136 yvcR V ABC transporter, ATP-binding protein
HHMJEDOE_03282 2.1e-183 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HHMJEDOE_03283 1.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_03284 1.4e-30
HHMJEDOE_03285 4.3e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HHMJEDOE_03286 1.6e-36 crh G Phosphocarrier protein Chr
HHMJEDOE_03287 1e-168 whiA K May be required for sporulation
HHMJEDOE_03288 2.6e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHMJEDOE_03289 6.3e-165 rapZ S Displays ATPase and GTPase activities
HHMJEDOE_03290 2e-88 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HHMJEDOE_03291 3.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHMJEDOE_03292 1.9e-94 usp CBM50 M protein conserved in bacteria
HHMJEDOE_03293 6.9e-270 S COG0457 FOG TPR repeat
HHMJEDOE_03294 8.3e-310 msbA2 3.6.3.44 V ABC transporter
HHMJEDOE_03296 0.0
HHMJEDOE_03297 5.4e-114
HHMJEDOE_03298 2.1e-97 Otg1 S Predicted membrane protein (DUF2339)
HHMJEDOE_03299 2e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HHMJEDOE_03300 1.1e-133 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HHMJEDOE_03301 8.2e-126 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HHMJEDOE_03302 3.3e-107 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HHMJEDOE_03303 4.4e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HHMJEDOE_03304 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HHMJEDOE_03305 3.7e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HHMJEDOE_03306 5.7e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HHMJEDOE_03307 7e-133 yvpB NU protein conserved in bacteria
HHMJEDOE_03308 4.3e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HHMJEDOE_03309 3.4e-78 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HHMJEDOE_03310 2.8e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HHMJEDOE_03311 9.3e-159 yvoD P COG0370 Fe2 transport system protein B
HHMJEDOE_03312 1e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHMJEDOE_03313 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHMJEDOE_03314 6.6e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHMJEDOE_03315 3.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHMJEDOE_03316 1.7e-128 yvoA K transcriptional
HHMJEDOE_03317 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HHMJEDOE_03318 4.5e-83 yvmB K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_03319 6.3e-159 yvmA EGP Major facilitator Superfamily
HHMJEDOE_03323 2e-08
HHMJEDOE_03326 2.8e-171 glcP G Major Facilitator Superfamily
HHMJEDOE_03327 1.6e-233 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHMJEDOE_03328 2.3e-157 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HHMJEDOE_03329 2.8e-172 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HHMJEDOE_03330 3.1e-246 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HHMJEDOE_03331 1.9e-162 ybaS 1.1.1.58 S Na -dependent transporter
HHMJEDOE_03332 7e-125 ybbA S Putative esterase
HHMJEDOE_03333 6.5e-174 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03334 2.2e-174 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03335 1.2e-150 feuA P Iron-uptake system-binding protein
HHMJEDOE_03336 4.7e-280 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HHMJEDOE_03337 8.7e-229 ybbC 3.2.1.52 S protein conserved in bacteria
HHMJEDOE_03338 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HHMJEDOE_03339 2.6e-239 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HHMJEDOE_03340 3.1e-227 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_03341 3.6e-141 ybbH K transcriptional
HHMJEDOE_03342 1.7e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHMJEDOE_03343 8.5e-79 ybbJ J acetyltransferase
HHMJEDOE_03344 5.3e-75 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HHMJEDOE_03350 7.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_03351 3.4e-96 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HHMJEDOE_03352 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHMJEDOE_03353 6.6e-220 ybbR S protein conserved in bacteria
HHMJEDOE_03354 6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHMJEDOE_03355 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHMJEDOE_03356 1.2e-98 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
HHMJEDOE_03357 5.9e-251 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHMJEDOE_03358 0.0 ybcC S Belongs to the UPF0753 family
HHMJEDOE_03359 2e-75 can 4.2.1.1 P carbonic anhydrase
HHMJEDOE_03360 4.6e-40
HHMJEDOE_03361 4.5e-53 ybcI S Uncharacterized conserved protein (DUF2294)
HHMJEDOE_03362 1.6e-57 ybzH K Helix-turn-helix domain
HHMJEDOE_03363 1.5e-198 ybcL EGP Major facilitator Superfamily
HHMJEDOE_03364 1.6e-110 V CAAX protease self-immunity
HHMJEDOE_03365 1.1e-79 skfF S ABC transporter
HHMJEDOE_03366 1.4e-84 C HEAT repeats
HHMJEDOE_03367 1.1e-66 txn CO Thioredoxin-like
HHMJEDOE_03368 4.3e-175 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HHMJEDOE_03369 3.7e-117 T Transcriptional regulatory protein, C terminal
HHMJEDOE_03370 8e-153 T His Kinase A (phospho-acceptor) domain
HHMJEDOE_03372 1.2e-127 KLT Protein tyrosine kinase
HHMJEDOE_03373 7e-145 ybdN
HHMJEDOE_03374 1.1e-182 ybdO S Domain of unknown function (DUF4885)
HHMJEDOE_03375 1.9e-253 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_03376 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HHMJEDOE_03377 2.7e-28 ybxH S Family of unknown function (DUF5370)
HHMJEDOE_03378 1.9e-31 ybxI 3.5.2.6 V beta-lactamase
HHMJEDOE_03379 4.6e-28 ybxI 3.5.2.6 V beta-lactamase
HHMJEDOE_03380 3.3e-31 ybxI 3.5.2.6 V beta-lactamase
HHMJEDOE_03381 5.7e-228 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HHMJEDOE_03382 1e-38 ybyB
HHMJEDOE_03383 4.3e-276 nptA P COG1283 Na phosphate symporter
HHMJEDOE_03384 8.6e-154 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HHMJEDOE_03385 1.8e-256 glpT G -transporter
HHMJEDOE_03386 3.5e-28 S Protein of unknown function (DUF2651)
HHMJEDOE_03387 2.8e-160 ybfA 3.4.15.5 K FR47-like protein
HHMJEDOE_03388 1.5e-212 ybfB G COG0477 Permeases of the major facilitator superfamily
HHMJEDOE_03390 0.0 ybfG M Domain of unknown function (DUF1906)
HHMJEDOE_03391 1.3e-149 ybfH EG EamA-like transporter family
HHMJEDOE_03392 8.5e-140 msmR K AraC-like ligand binding domain
HHMJEDOE_03393 5e-150 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HHMJEDOE_03394 1.1e-79 M nucleic acid phosphodiester bond hydrolysis
HHMJEDOE_03395 1.9e-206 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HHMJEDOE_03396 8.4e-168 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HHMJEDOE_03398 1.8e-148 S Alpha/beta hydrolase family
HHMJEDOE_03399 7.3e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHMJEDOE_03400 3.3e-83 ybfM S SNARE associated Golgi protein
HHMJEDOE_03401 1.4e-142 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HHMJEDOE_03402 3.4e-40 ybfN
HHMJEDOE_03403 3.5e-07 S Erythromycin esterase
HHMJEDOE_03404 4.9e-187 yceA S Belongs to the UPF0176 family
HHMJEDOE_03405 2e-209 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHMJEDOE_03406 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HHMJEDOE_03407 1.7e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHMJEDOE_03408 1.3e-126 K UTRA
HHMJEDOE_03410 2e-189 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HHMJEDOE_03411 6.8e-254 mmuP E amino acid
HHMJEDOE_03412 3e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HHMJEDOE_03413 4.9e-252 agcS E Sodium alanine symporter
HHMJEDOE_03414 2e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
HHMJEDOE_03415 1.4e-218 phoQ 2.7.13.3 T Histidine kinase
HHMJEDOE_03416 2.5e-159 glnL T Regulator
HHMJEDOE_03417 1.1e-167 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HHMJEDOE_03418 9.4e-267 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHMJEDOE_03419 4.7e-252 gudP G COG0477 Permeases of the major facilitator superfamily
HHMJEDOE_03420 3.6e-260 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HHMJEDOE_03421 4e-122 ycbG K FCD
HHMJEDOE_03422 1.5e-291 garD 4.2.1.42, 4.2.1.7 G Altronate
HHMJEDOE_03423 5e-157 ycbJ S Macrolide 2'-phosphotransferase
HHMJEDOE_03424 3.7e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HHMJEDOE_03425 1.4e-143 eamA1 EG spore germination
HHMJEDOE_03426 9.1e-119 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_03427 1.1e-154 T PhoQ Sensor
HHMJEDOE_03428 4.7e-163 ycbN V ABC transporter, ATP-binding protein
HHMJEDOE_03429 2.1e-107 S ABC-2 family transporter protein
HHMJEDOE_03430 1.4e-52 ycbP S Protein of unknown function (DUF2512)
HHMJEDOE_03431 1.7e-96 O Belongs to the serpin family
HHMJEDOE_03432 1.2e-76 sleB 3.5.1.28 M Cell wall
HHMJEDOE_03433 4.6e-129 ycbR T vWA found in TerF C terminus
HHMJEDOE_03434 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HHMJEDOE_03435 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HHMJEDOE_03436 8.6e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HHMJEDOE_03437 1.4e-113 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHMJEDOE_03438 7.3e-179 ycbU E Selenocysteine lyase
HHMJEDOE_03439 4e-230 lmrB EGP the major facilitator superfamily
HHMJEDOE_03440 1.6e-97 yxaF K Transcriptional regulator
HHMJEDOE_03441 6.5e-183 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HHMJEDOE_03442 9.9e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HHMJEDOE_03443 5.5e-57 S RDD family
HHMJEDOE_03444 3.9e-193 yccF K DNA-templated transcriptional preinitiation complex assembly
HHMJEDOE_03445 8.3e-131 2.7.13.3 T GHKL domain
HHMJEDOE_03446 4e-122 lytR_2 T LytTr DNA-binding domain
HHMJEDOE_03447 7.2e-130 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HHMJEDOE_03448 2.5e-193 natB CP ABC-2 family transporter protein
HHMJEDOE_03449 3.9e-165 yccK C Aldo keto reductase
HHMJEDOE_03450 3.6e-175 ycdA S Domain of unknown function (DUF5105)
HHMJEDOE_03451 1.9e-66 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_03452 6.7e-111 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_03453 7.7e-239 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HHMJEDOE_03454 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
HHMJEDOE_03455 7.2e-166 S response regulator aspartate phosphatase
HHMJEDOE_03456 1.7e-134 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_03457 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HHMJEDOE_03458 7.6e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
HHMJEDOE_03459 7.9e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HHMJEDOE_03460 3.3e-131 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HHMJEDOE_03461 2.3e-176 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HHMJEDOE_03462 5.3e-107 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HHMJEDOE_03463 2e-103 yceD T proteins involved in stress response, homologs of TerZ and
HHMJEDOE_03464 1.5e-106 yceE T proteins involved in stress response, homologs of TerZ and
HHMJEDOE_03465 4.5e-135 terC P Protein of unknown function (DUF475)
HHMJEDOE_03466 2e-310 yceG S Putative component of 'biosynthetic module'
HHMJEDOE_03467 4.8e-191 yceH P Belongs to the TelA family
HHMJEDOE_03468 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
HHMJEDOE_03469 1e-194 yceJ EGP Uncharacterised MFS-type transporter YbfB
HHMJEDOE_03470 4.7e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHMJEDOE_03471 6.9e-226 proV 3.6.3.32 E glycine betaine
HHMJEDOE_03472 2.2e-127 opuAB P glycine betaine
HHMJEDOE_03473 4.6e-160 opuAC E glycine betaine
HHMJEDOE_03474 5.6e-214 amhX S amidohydrolase
HHMJEDOE_03475 6.9e-254 ycgA S Membrane
HHMJEDOE_03476 2.7e-77 ycgB
HHMJEDOE_03477 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HHMJEDOE_03478 8.9e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHMJEDOE_03479 3.2e-284 lctP C L-lactate permease
HHMJEDOE_03480 2.1e-256 mdr EGP Major facilitator Superfamily
HHMJEDOE_03481 1.2e-74 emrR K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_03482 3.7e-111 ycgF E Lysine exporter protein LysE YggA
HHMJEDOE_03483 1.5e-143 yqcI S YqcI/YcgG family
HHMJEDOE_03484 2.8e-241 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_03485 1e-110 ycgI S Domain of unknown function (DUF1989)
HHMJEDOE_03486 5.5e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHMJEDOE_03487 7.6e-98 tmrB S AAA domain
HHMJEDOE_03488 1.5e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HHMJEDOE_03489 2.7e-132 yafE Q ubiE/COQ5 methyltransferase family
HHMJEDOE_03490 1.4e-165 oxyR3 K LysR substrate binding domain
HHMJEDOE_03491 3.7e-179 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HHMJEDOE_03492 4.7e-140 ycgL S Predicted nucleotidyltransferase
HHMJEDOE_03493 2.9e-165 ycgM E Proline dehydrogenase
HHMJEDOE_03494 1.5e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HHMJEDOE_03495 5.1e-257 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HHMJEDOE_03496 3.4e-225 ycgP QT COG2508 Regulator of polyketide synthase expression
HHMJEDOE_03497 8.5e-143 ycgQ S membrane
HHMJEDOE_03498 1.9e-140 ycgR S permeases
HHMJEDOE_03499 1.2e-144 I alpha/beta hydrolase fold
HHMJEDOE_03500 3.3e-186 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HHMJEDOE_03501 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HHMJEDOE_03502 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
HHMJEDOE_03503 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HHMJEDOE_03504 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HHMJEDOE_03505 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HHMJEDOE_03506 3.3e-217 nasA P COG2223 Nitrate nitrite transporter
HHMJEDOE_03507 1.3e-157 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HHMJEDOE_03508 5e-84 yciB M ErfK YbiS YcfS YnhG
HHMJEDOE_03510 8.3e-221 yciC S GTPases (G3E family)
HHMJEDOE_03511 7.8e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HHMJEDOE_03512 1.6e-125 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HHMJEDOE_03513 1.4e-201 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HHMJEDOE_03514 1.6e-68 yckC S membrane
HHMJEDOE_03515 4.9e-46 yckD S Protein of unknown function (DUF2680)
HHMJEDOE_03516 1.9e-39 K MarR family
HHMJEDOE_03517 2.1e-23
HHMJEDOE_03518 3e-120 S AAA domain
HHMJEDOE_03519 9.2e-291 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHMJEDOE_03520 7.2e-68 nin S Competence protein J (ComJ)
HHMJEDOE_03521 3e-67 nucA M Deoxyribonuclease NucA/NucB
HHMJEDOE_03522 8.5e-150 tlpC 2.7.13.3 NT chemotaxis protein
HHMJEDOE_03523 6e-89 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HHMJEDOE_03524 1.4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HHMJEDOE_03525 5.3e-62 hxlR K transcriptional
HHMJEDOE_03528 1e-156 ydhU P Catalase
HHMJEDOE_03529 1.2e-197 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HHMJEDOE_03530 8.5e-176 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHMJEDOE_03531 4e-159 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HHMJEDOE_03532 4.5e-129 ydhQ K UTRA
HHMJEDOE_03533 3e-270 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHMJEDOE_03534 1.3e-227 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHMJEDOE_03535 9e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHMJEDOE_03536 1.8e-45 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HHMJEDOE_03537 1.1e-196 pbuE EGP Major facilitator Superfamily
HHMJEDOE_03538 1.1e-93 ydhK M Protein of unknown function (DUF1541)
HHMJEDOE_03539 5.5e-162 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHMJEDOE_03540 8.6e-68 K Acetyltransferase (GNAT) domain
HHMJEDOE_03542 5.3e-57 frataxin S Domain of unknown function (DU1801)
HHMJEDOE_03543 1.4e-251 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HHMJEDOE_03544 3e-109
HHMJEDOE_03545 3.3e-217 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HHMJEDOE_03546 1e-229 ydhD M Glycosyl hydrolase
HHMJEDOE_03547 1.8e-116 ydhC K FCD
HHMJEDOE_03548 1.3e-118 ydhB S membrane transporter protein
HHMJEDOE_03549 1e-205 tcaB EGP Major facilitator Superfamily
HHMJEDOE_03550 9.6e-21 azlD S Branched-chain amino acid transport protein (AzlD)
HHMJEDOE_03551 9.2e-69 ydgJ K Winged helix DNA-binding domain
HHMJEDOE_03552 4e-113 drgA C nitroreductase
HHMJEDOE_03553 0.0 ydgH S drug exporters of the RND superfamily
HHMJEDOE_03554 5.4e-75 K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_03555 1.1e-79 dinB S DinB family
HHMJEDOE_03556 1.1e-245 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HHMJEDOE_03557 1.7e-285 expZ S ABC transporter
HHMJEDOE_03558 2.7e-74 yycN 2.3.1.128 K Acetyltransferase
HHMJEDOE_03559 4.8e-44 S DoxX-like family
HHMJEDOE_03560 3.6e-87 K Bacterial regulatory proteins, tetR family
HHMJEDOE_03561 2.1e-34 ydgB S Spore germination protein gerPA/gerPF
HHMJEDOE_03562 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
HHMJEDOE_03563 1.6e-65 cotP O Belongs to the small heat shock protein (HSP20) family
HHMJEDOE_03564 2.3e-11 ydfS S Protein of unknown function (DUF421)
HHMJEDOE_03565 8e-66 ydfS S Protein of unknown function (DUF421)
HHMJEDOE_03566 5.2e-31 ydfR S Protein of unknown function (DUF421)
HHMJEDOE_03568 1.1e-28
HHMJEDOE_03569 2.1e-14 ydgA S Spore germination protein gerPA/gerPF
HHMJEDOE_03571 6.2e-82 paiB K Transcriptional regulator
HHMJEDOE_03572 4.1e-203 K helix_turn_helix gluconate operon transcriptional repressor
HHMJEDOE_03573 1.5e-53 traF CO Thioredoxin
HHMJEDOE_03574 9.8e-62 mhqP S DoxX
HHMJEDOE_03575 1.6e-179 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HHMJEDOE_03576 1.2e-109 ydfN C nitroreductase
HHMJEDOE_03577 6.1e-152 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHMJEDOE_03578 5.7e-134 K Bacterial transcription activator, effector binding domain
HHMJEDOE_03579 2.2e-109 S Protein of unknown function (DUF554)
HHMJEDOE_03580 5.9e-73 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HHMJEDOE_03581 5.2e-95 3.1.3.18, 3.2.2.9 F haloacid dehalogenase-like hydrolase
HHMJEDOE_03582 0.0 ydfJ S drug exporters of the RND superfamily
HHMJEDOE_03583 1.5e-107 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_03584 2.9e-168 ydfH 2.7.13.3 T Histidine kinase
HHMJEDOE_03586 3.5e-71 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHMJEDOE_03587 2.9e-109 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HHMJEDOE_03588 1e-108 ydfE S Flavin reductase like domain
HHMJEDOE_03589 3.2e-259 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_03590 6.1e-147 ydfC EG EamA-like transporter family
HHMJEDOE_03591 2.2e-113 ydfB J GNAT acetyltransferase
HHMJEDOE_03592 6.6e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HHMJEDOE_03593 4.6e-217 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHMJEDOE_03594 5e-54 arsR K transcriptional
HHMJEDOE_03595 3e-99 ydeS K Transcriptional regulator
HHMJEDOE_03596 7.4e-177 ydeR EGP Major facilitator Superfamily
HHMJEDOE_03597 2.6e-147 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HHMJEDOE_03598 1.2e-68 maoC I N-terminal half of MaoC dehydratase
HHMJEDOE_03599 2.3e-254 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_03600 5.2e-148 ydeK EG -transporter
HHMJEDOE_03601 5.1e-78 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HHMJEDOE_03602 0.0 M Domain of unknown function DUF11
HHMJEDOE_03603 1.6e-67 lrpA K transcriptional
HHMJEDOE_03604 2.9e-134 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HHMJEDOE_03605 3.3e-253 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHMJEDOE_03606 1.7e-154 K Transcriptional regulator
HHMJEDOE_03607 4e-58
HHMJEDOE_03608 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HHMJEDOE_03609 2.9e-60 ykvN K Transcriptional regulator
HHMJEDOE_03611 5.6e-93 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HHMJEDOE_03612 5.1e-47 ydeH
HHMJEDOE_03613 1.6e-196 ydeG EGP Major facilitator superfamily
HHMJEDOE_03614 1.2e-247 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_03615 3.6e-149 ydeE K AraC family transcriptional regulator
HHMJEDOE_03616 4.2e-19 rok K Repressor of ComK
HHMJEDOE_03617 4.2e-213 brnQ E Component of the transport system for branched-chain amino acids
HHMJEDOE_03618 5.4e-12 paaI Q Thioesterase superfamily
HHMJEDOE_03619 2.6e-47 azlD E Branched-chain amino acid transport protein (AzlD)
HHMJEDOE_03620 4.4e-127 azlC E AzlC protein
HHMJEDOE_03621 1.4e-75 bkdR K helix_turn_helix ASNC type
HHMJEDOE_03622 3.5e-74 carD K Transcription factor
HHMJEDOE_03623 3e-30 cspL K Cold shock
HHMJEDOE_03624 8.9e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HHMJEDOE_03632 1.7e-81 ydcK S Belongs to the SprT family
HHMJEDOE_03633 0.0 yhgF K COG2183 Transcriptional accessory protein
HHMJEDOE_03634 4.2e-69 ydcH K helix_turn_helix multiple antibiotic resistance protein
HHMJEDOE_03635 1e-56 ydcG S EVE domain
HHMJEDOE_03636 8.9e-16 S Polyketide cyclase / dehydrase and lipid transport
HHMJEDOE_03637 6.9e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HHMJEDOE_03638 2.2e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HHMJEDOE_03639 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HHMJEDOE_03640 2.3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
HHMJEDOE_03641 4.8e-185 rsbU 3.1.3.3 KT phosphatase
HHMJEDOE_03642 1.5e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HHMJEDOE_03643 6.8e-57 rsbS T antagonist
HHMJEDOE_03644 1.3e-140 rsbR T Positive regulator of sigma-B
HHMJEDOE_03645 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HHMJEDOE_03646 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HHMJEDOE_03647 3.8e-210 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHMJEDOE_03648 3.5e-180 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HHMJEDOE_03649 5.8e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHMJEDOE_03650 4.2e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HHMJEDOE_03651 2.7e-245 ydbT S Membrane
HHMJEDOE_03652 1e-81 ydbS S Bacterial PH domain
HHMJEDOE_03653 1.5e-243 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHMJEDOE_03654 2.5e-245 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHMJEDOE_03655 1.8e-198 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHMJEDOE_03656 1.5e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHMJEDOE_03657 8.4e-146 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHMJEDOE_03659 1.1e-18 S Fur-regulated basic protein B
HHMJEDOE_03660 5.9e-208 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HHMJEDOE_03661 4.6e-52 ydbL
HHMJEDOE_03662 1.8e-120 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HHMJEDOE_03663 6.1e-163 ydbJ V ABC transporter, ATP-binding protein
HHMJEDOE_03664 4.3e-204 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHMJEDOE_03665 3.3e-173 ydbI S AI-2E family transporter
HHMJEDOE_03666 8.2e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHMJEDOE_03667 3.9e-114 dctR T COG4565 Response regulator of citrate malate metabolism
HHMJEDOE_03668 1.5e-289 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHMJEDOE_03669 4.1e-187 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HHMJEDOE_03670 1.3e-151 ydbD P Catalase
HHMJEDOE_03671 7.4e-48 ydbC S Domain of unknown function (DUF4937
HHMJEDOE_03672 3e-54 ydbB G Cupin domain
HHMJEDOE_03674 3.8e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HHMJEDOE_03675 2.1e-68 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HHMJEDOE_03676 1.8e-16 ydaS S membrane
HHMJEDOE_03677 3.6e-222 mntH P H( )-stimulated, divalent metal cation uptake system
HHMJEDOE_03678 3e-38
HHMJEDOE_03680 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HHMJEDOE_03681 2.5e-61 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HHMJEDOE_03682 0.0 ydaO E amino acid
HHMJEDOE_03683 0.0 ydaN S Bacterial cellulose synthase subunit
HHMJEDOE_03684 2.5e-231 ydaM M Glycosyl transferase family group 2
HHMJEDOE_03685 1.7e-307 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HHMJEDOE_03686 3.1e-145 ydaK T Diguanylate cyclase, GGDEF domain
HHMJEDOE_03687 9.3e-195 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HHMJEDOE_03688 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHMJEDOE_03689 1.2e-73 lrpC K Transcriptional regulator
HHMJEDOE_03690 2.3e-22 XK27_00085 K transcriptional
HHMJEDOE_03691 1.4e-46
HHMJEDOE_03692 1.4e-44 ydzA EGP Major facilitator Superfamily
HHMJEDOE_03693 1.5e-136 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HHMJEDOE_03694 2e-76 ydaG 1.4.3.5 S general stress protein
HHMJEDOE_03695 7.3e-95 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HHMJEDOE_03696 5.1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HHMJEDOE_03697 2.2e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_03698 3.1e-91 ydaC Q Methyltransferase domain
HHMJEDOE_03699 1e-279 ydaB IQ acyl-CoA ligase
HHMJEDOE_03700 0.0 mtlR K transcriptional regulator, MtlR
HHMJEDOE_03701 4e-167 ydhF S Oxidoreductase
HHMJEDOE_03702 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HHMJEDOE_03703 3.5e-48 yczJ S biosynthesis
HHMJEDOE_03705 1.5e-112 ycsK E anatomical structure formation involved in morphogenesis
HHMJEDOE_03706 3.4e-127 kipR K Transcriptional regulator
HHMJEDOE_03707 3.1e-176 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HHMJEDOE_03708 1e-128 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HHMJEDOE_03709 7.1e-136 ycsI S Belongs to the D-glutamate cyclase family
HHMJEDOE_03710 9.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HHMJEDOE_03711 1.1e-133 ycsF S Belongs to the UPF0271 (lamB) family
HHMJEDOE_03712 7.5e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HHMJEDOE_03714 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HHMJEDOE_03715 1.2e-90 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HHMJEDOE_03716 2.7e-89 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HHMJEDOE_03717 9.7e-197 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HHMJEDOE_03718 1.5e-200 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HHMJEDOE_03719 2.2e-70 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HHMJEDOE_03720 3.2e-235 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HHMJEDOE_03721 4.1e-51
HHMJEDOE_03722 1.7e-102 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HHMJEDOE_03723 1.9e-292 ycnJ P protein, homolog of Cu resistance protein CopC
HHMJEDOE_03724 1.3e-92 ycnI S protein conserved in bacteria
HHMJEDOE_03725 3.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_03726 5.4e-145 glcU U Glucose uptake
HHMJEDOE_03727 2.3e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HHMJEDOE_03728 1.2e-241 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HHMJEDOE_03729 5.6e-256 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HHMJEDOE_03730 3.7e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HHMJEDOE_03731 6.1e-45 ycnE S Monooxygenase
HHMJEDOE_03732 1.1e-130 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HHMJEDOE_03733 1.6e-149 ycnC K Transcriptional regulator
HHMJEDOE_03734 2.1e-247 ycnB EGP Major facilitator Superfamily
HHMJEDOE_03735 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HHMJEDOE_03736 1.7e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HHMJEDOE_03737 1.4e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03738 1.7e-160 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHMJEDOE_03739 2.5e-245 lysC 2.7.2.4 E Belongs to the aspartokinase family
HHMJEDOE_03743 3.9e-74 S aspartate phosphatase
HHMJEDOE_03744 2.7e-247 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHMJEDOE_03745 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HHMJEDOE_03746 1.7e-199 yclI V ABC transporter (permease) YclI
HHMJEDOE_03747 1.7e-117 yclH P ABC transporter
HHMJEDOE_03748 1.4e-190 gerKB F Spore germination protein
HHMJEDOE_03749 3.5e-206 gerKC S spore germination
HHMJEDOE_03750 1.3e-264 gerKA EG Spore germination protein
HHMJEDOE_03752 1e-288 yclG M Pectate lyase superfamily protein
HHMJEDOE_03753 8.9e-265 dtpT E amino acid peptide transporter
HHMJEDOE_03754 5.1e-96 L Integrase core domain
HHMJEDOE_03755 8.5e-86 thiT S Thiamine transporter protein (Thia_YuaJ)
HHMJEDOE_03756 8.4e-85 M1-753 M FR47-like protein
HHMJEDOE_03757 1e-183 yuaG 3.4.21.72 S protein conserved in bacteria
HHMJEDOE_03758 1.7e-69 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HHMJEDOE_03759 7.2e-78 yuaE S DinB superfamily
HHMJEDOE_03760 1.8e-96 yuaD
HHMJEDOE_03761 4.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HHMJEDOE_03762 5e-276 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HHMJEDOE_03763 3.1e-90 yuaC K Belongs to the GbsR family
HHMJEDOE_03764 5.3e-90 yuaB
HHMJEDOE_03765 1.1e-118 ktrA P COG0569 K transport systems, NAD-binding component
HHMJEDOE_03766 2.9e-230 ktrB P Potassium
HHMJEDOE_03767 1.3e-38 yiaA S yiaA/B two helix domain
HHMJEDOE_03768 5.7e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHMJEDOE_03769 9.7e-243 yubD P Major Facilitator Superfamily
HHMJEDOE_03770 1.3e-82 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HHMJEDOE_03772 5.2e-129 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HHMJEDOE_03773 5.1e-191 yubA S transporter activity
HHMJEDOE_03774 2.7e-172 ygjR S Oxidoreductase
HHMJEDOE_03775 2.9e-240 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HHMJEDOE_03776 2.5e-52 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HHMJEDOE_03777 1.7e-247 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HHMJEDOE_03778 4.6e-127 fucR K COG1349 Transcriptional regulators of sugar metabolism
HHMJEDOE_03779 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HHMJEDOE_03780 2.9e-218 mcpA NT chemotaxis protein
HHMJEDOE_03781 3.3e-283 mcpA NT chemotaxis protein
HHMJEDOE_03782 1.5e-206 mcpA NT chemotaxis protein
HHMJEDOE_03783 4e-212 mcpA NT chemotaxis protein
HHMJEDOE_03784 1.9e-130 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HHMJEDOE_03785 8e-36
HHMJEDOE_03786 3.5e-70 yugU S Uncharacterised protein family UPF0047
HHMJEDOE_03787 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HHMJEDOE_03788 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HHMJEDOE_03789 9.2e-116 yugP S Zn-dependent protease
HHMJEDOE_03790 4.8e-36
HHMJEDOE_03791 1.2e-40 mstX S Membrane-integrating protein Mistic
HHMJEDOE_03792 4.7e-169 yugO P COG1226 Kef-type K transport systems
HHMJEDOE_03793 1.6e-70 yugN S YugN-like family
HHMJEDOE_03795 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
HHMJEDOE_03796 6e-224 yugK C Dehydrogenase
HHMJEDOE_03797 6.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HHMJEDOE_03798 1.1e-34 yuzA S Domain of unknown function (DUF378)
HHMJEDOE_03799 4.4e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HHMJEDOE_03800 4.8e-213 yugH 2.6.1.1 E Aminotransferase
HHMJEDOE_03801 4.7e-85 alaR K Transcriptional regulator
HHMJEDOE_03802 1.2e-149 yugF I Hydrolase
HHMJEDOE_03803 4.3e-37 yugE S Domain of unknown function (DUF1871)
HHMJEDOE_03804 1.2e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HHMJEDOE_03805 4e-221 T PhoQ Sensor
HHMJEDOE_03806 2.2e-66 kapB G Kinase associated protein B
HHMJEDOE_03807 2.5e-112 kapD L the KinA pathway to sporulation
HHMJEDOE_03809 2.4e-179 yuxJ EGP Major facilitator Superfamily
HHMJEDOE_03810 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HHMJEDOE_03811 2.6e-73 yuxK S protein conserved in bacteria
HHMJEDOE_03812 2e-76 yufK S Family of unknown function (DUF5366)
HHMJEDOE_03813 2.4e-287 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HHMJEDOE_03814 1.4e-122 dcuR T COG4565 Response regulator of citrate malate metabolism
HHMJEDOE_03815 1.7e-185 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HHMJEDOE_03816 1.2e-259 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HHMJEDOE_03817 1.8e-179 yufP S Belongs to the binding-protein-dependent transport system permease family
HHMJEDOE_03818 5.2e-165 yufQ S Belongs to the binding-protein-dependent transport system permease family
HHMJEDOE_03819 1.8e-227 maeN C COG3493 Na citrate symporter
HHMJEDOE_03820 8.5e-15
HHMJEDOE_03821 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HHMJEDOE_03822 7.7e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHMJEDOE_03823 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHMJEDOE_03824 1.4e-257 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHMJEDOE_03825 2.7e-74 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHMJEDOE_03826 6.1e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HHMJEDOE_03827 2e-56 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HHMJEDOE_03828 4.3e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
HHMJEDOE_03829 1.1e-115 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_03830 0.0 comP 2.7.13.3 T Histidine kinase
HHMJEDOE_03832 3.7e-147 comQ H Belongs to the FPP GGPP synthase family
HHMJEDOE_03834 7.7e-24 yuzC
HHMJEDOE_03835 2.6e-225 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HHMJEDOE_03836 8.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHMJEDOE_03837 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HHMJEDOE_03838 1.8e-58 yueI S Protein of unknown function (DUF1694)
HHMJEDOE_03839 7.2e-34 yueH S YueH-like protein
HHMJEDOE_03840 9.6e-30 yueG S Spore germination protein gerPA/gerPF
HHMJEDOE_03841 2.1e-186 yueF S transporter activity
HHMJEDOE_03842 2.9e-24 S Protein of unknown function (DUF2642)
HHMJEDOE_03843 7e-95 yueE S phosphohydrolase
HHMJEDOE_03844 1.3e-123 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHMJEDOE_03845 1.7e-60 yueC S Family of unknown function (DUF5383)
HHMJEDOE_03846 0.0 esaA S type VII secretion protein EsaA
HHMJEDOE_03847 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HHMJEDOE_03848 1e-190 essB S WXG100 protein secretion system (Wss), protein YukC
HHMJEDOE_03849 1.8e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HHMJEDOE_03850 2.8e-45 esxA S Belongs to the WXG100 family
HHMJEDOE_03851 1.6e-219 yukF QT Transcriptional regulator
HHMJEDOE_03852 2.8e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HHMJEDOE_03853 6.8e-127 yukJ S Uncharacterized conserved protein (DUF2278)
HHMJEDOE_03854 6.5e-36 mbtH S MbtH-like protein
HHMJEDOE_03855 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHMJEDOE_03856 9.9e-169 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HHMJEDOE_03857 1e-301 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HHMJEDOE_03858 4.4e-206 entC 5.4.4.2 HQ Isochorismate synthase
HHMJEDOE_03859 2.8e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HHMJEDOE_03860 3.5e-152 besA S Putative esterase
HHMJEDOE_03861 3.3e-117 yuiH S Oxidoreductase molybdopterin binding domain
HHMJEDOE_03862 1.6e-87 bioY S Biotin biosynthesis protein
HHMJEDOE_03863 4.3e-194 yuiF S antiporter
HHMJEDOE_03864 3e-268 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HHMJEDOE_03865 2.5e-75 yuiD S protein conserved in bacteria
HHMJEDOE_03866 2.4e-113 yuiC S protein conserved in bacteria
HHMJEDOE_03867 4.6e-25 yuiB S Putative membrane protein
HHMJEDOE_03868 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
HHMJEDOE_03869 2.3e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HHMJEDOE_03871 6.3e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHMJEDOE_03872 1.2e-78 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHMJEDOE_03873 5.3e-62 erpA S Belongs to the HesB IscA family
HHMJEDOE_03874 3.2e-158 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HHMJEDOE_03875 9.4e-196 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HHMJEDOE_03876 3.2e-39 yuzB S Belongs to the UPF0349 family
HHMJEDOE_03877 1.9e-197 yutJ 1.6.99.3 C NADH dehydrogenase
HHMJEDOE_03878 5.3e-53 yuzD S protein conserved in bacteria
HHMJEDOE_03879 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HHMJEDOE_03880 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HHMJEDOE_03881 3.1e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHMJEDOE_03882 1.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HHMJEDOE_03883 1.6e-238 hom 1.1.1.3 E homoserine dehydrogenase
HHMJEDOE_03884 4.5e-191 yutH S Spore coat protein
HHMJEDOE_03885 2.3e-75 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HHMJEDOE_03886 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHMJEDOE_03887 1.2e-68 yutE S Protein of unknown function DUF86
HHMJEDOE_03888 9.7e-48 yutD S protein conserved in bacteria
HHMJEDOE_03889 7.5e-104 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HHMJEDOE_03890 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HHMJEDOE_03891 5.1e-192 lytH M Peptidase, M23
HHMJEDOE_03892 1.7e-129 yunB S Sporulation protein YunB (Spo_YunB)
HHMJEDOE_03893 1.7e-48 yunC S Domain of unknown function (DUF1805)
HHMJEDOE_03894 4.6e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHMJEDOE_03895 1.5e-136 yunE S membrane transporter protein
HHMJEDOE_03896 5.7e-171 yunF S Protein of unknown function DUF72
HHMJEDOE_03897 1e-54 yunG
HHMJEDOE_03898 2.4e-101 2.4.1.173 GT1 CG UDP-glucoronosyl and UDP-glucosyl transferase
HHMJEDOE_03899 1.5e-242 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HHMJEDOE_03900 6.4e-293 pucR QT COG2508 Regulator of polyketide synthase expression
HHMJEDOE_03901 1.3e-217 pbuX F Permease family
HHMJEDOE_03902 2.6e-212 pbuX F xanthine
HHMJEDOE_03903 1.9e-254 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HHMJEDOE_03904 2.7e-50 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HHMJEDOE_03905 1.2e-83 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HHMJEDOE_03906 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HHMJEDOE_03907 4.3e-131 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HHMJEDOE_03908 3e-94 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HHMJEDOE_03909 1.1e-165 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HHMJEDOE_03911 3.4e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HHMJEDOE_03912 1.5e-220 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HHMJEDOE_03913 1.4e-158 bsn L Ribonuclease
HHMJEDOE_03914 4.3e-195 msmX P Belongs to the ABC transporter superfamily
HHMJEDOE_03915 5.2e-133 yurK K UTRA
HHMJEDOE_03916 3.7e-154 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HHMJEDOE_03917 2.2e-165 yurM P COG0395 ABC-type sugar transport system, permease component
HHMJEDOE_03918 4.5e-155 yurN G Binding-protein-dependent transport system inner membrane component
HHMJEDOE_03919 3.8e-232 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HHMJEDOE_03920 7.7e-180 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HHMJEDOE_03921 1.9e-62 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HHMJEDOE_03922 7.3e-195 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HHMJEDOE_03924 1.7e-36
HHMJEDOE_03925 4.6e-271 sufB O FeS cluster assembly
HHMJEDOE_03926 3.2e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HHMJEDOE_03927 4.3e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HHMJEDOE_03928 3.8e-243 sufD O assembly protein SufD
HHMJEDOE_03929 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HHMJEDOE_03930 4.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HHMJEDOE_03931 3.3e-144 metQ P Belongs to the NlpA lipoprotein family
HHMJEDOE_03932 8.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HHMJEDOE_03933 1.5e-181 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHMJEDOE_03934 2.3e-54 yusD S SCP-2 sterol transfer family
HHMJEDOE_03935 2e-52 traF CO Thioredoxin
HHMJEDOE_03936 2.6e-71 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HHMJEDOE_03937 3e-37 yusG S Protein of unknown function (DUF2553)
HHMJEDOE_03938 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HHMJEDOE_03939 1.4e-62 arsC 1.20.4.1 P Belongs to the ArsC family
HHMJEDOE_03940 8.4e-302 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HHMJEDOE_03941 9.7e-214 fadA 2.3.1.16 I Belongs to the thiolase family
HHMJEDOE_03942 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HHMJEDOE_03943 8.1e-09 S YuzL-like protein
HHMJEDOE_03944 1.4e-159 fadM E Proline dehydrogenase
HHMJEDOE_03945 5.1e-40
HHMJEDOE_03946 9.3e-53 yusN M Coat F domain
HHMJEDOE_03947 1.2e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HHMJEDOE_03948 6.7e-282 yusP P Major facilitator superfamily
HHMJEDOE_03949 3.3e-102 S response regulator aspartate phosphatase
HHMJEDOE_03950 3.8e-84 ywmF S Peptidase M50
HHMJEDOE_03951 5.1e-08 csbD K CsbD-like
HHMJEDOE_03952 7.7e-217 urtA E Receptor family ligand binding region
HHMJEDOE_03953 5.6e-145 urtB E Belongs to the binding-protein-dependent transport system permease family
HHMJEDOE_03954 1.2e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
HHMJEDOE_03955 6.3e-118 urtD S ATPases associated with a variety of cellular activities
HHMJEDOE_03956 8e-115 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HHMJEDOE_03957 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HHMJEDOE_03958 1.1e-59 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HHMJEDOE_03959 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HHMJEDOE_03960 1.6e-62 ywnA K Transcriptional regulator
HHMJEDOE_03961 1.9e-107 ywnB S NAD(P)H-binding
HHMJEDOE_03962 6.1e-56 ywnC S Family of unknown function (DUF5362)
HHMJEDOE_03963 6.8e-131 mta K transcriptional
HHMJEDOE_03964 7.8e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHMJEDOE_03965 3.5e-68 ywnF S Family of unknown function (DUF5392)
HHMJEDOE_03966 5.5e-192 spsF 2.5.1.56, 2.7.7.92 M NeuB family
HHMJEDOE_03967 2.1e-11 ywnC S Family of unknown function (DUF5362)
HHMJEDOE_03968 4.3e-86 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HHMJEDOE_03969 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HHMJEDOE_03970 7.9e-65 ywnJ S VanZ like family
HHMJEDOE_03971 2.5e-98 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HHMJEDOE_03972 1.6e-58 nrgB K Belongs to the P(II) protein family
HHMJEDOE_03973 7.7e-222 amt P Ammonium transporter
HHMJEDOE_03974 1.9e-72
HHMJEDOE_03975 6.3e-102 phzA Q Isochorismatase family
HHMJEDOE_03976 1.1e-226 ywoD EGP Major facilitator superfamily
HHMJEDOE_03977 6.8e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HHMJEDOE_03978 1e-214 ywoF P Right handed beta helix region
HHMJEDOE_03979 2.1e-197 ywoG EGP Major facilitator Superfamily
HHMJEDOE_03980 5.1e-69 ywoH K COG1846 Transcriptional regulators
HHMJEDOE_03981 3e-44 spoIIID K Stage III sporulation protein D
HHMJEDOE_03982 3.5e-180 mbl D Rod shape-determining protein
HHMJEDOE_03983 1.5e-117 flhO N flagellar basal body
HHMJEDOE_03984 1.4e-139 flhP N flagellar basal body
HHMJEDOE_03985 8.3e-188 S aspartate phosphatase
HHMJEDOE_03986 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHMJEDOE_03987 4.4e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHMJEDOE_03988 0.0 ywpD T PhoQ Sensor
HHMJEDOE_03989 6.3e-167 M1-574 T Transcriptional regulatory protein, C terminal
HHMJEDOE_03990 0.0 M1-568 M cell wall anchor domain
HHMJEDOE_03991 3.2e-86 srtA 3.4.22.70 M Sortase family
HHMJEDOE_03992 1.7e-64 ywpF S YwpF-like protein
HHMJEDOE_03993 3e-63 ywpG
HHMJEDOE_03994 1.4e-56 ssbB L Single-stranded DNA-binding protein
HHMJEDOE_03995 6.6e-134 glcR K COG1349 Transcriptional regulators of sugar metabolism
HHMJEDOE_03996 3.5e-144 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HHMJEDOE_03997 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HHMJEDOE_03998 6.4e-301 ywqB S SWIM zinc finger
HHMJEDOE_03999 6e-17
HHMJEDOE_04000 5.7e-111 ywqC M biosynthesis protein
HHMJEDOE_04001 1.9e-108 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HHMJEDOE_04002 4.5e-127 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HHMJEDOE_04003 3.7e-238 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHMJEDOE_04004 3.3e-149 ywqG S Domain of unknown function (DUF1963)
HHMJEDOE_04005 2.6e-23 S Domain of unknown function (DUF5082)
HHMJEDOE_04006 3.9e-38 ywqI S Family of unknown function (DUF5344)
HHMJEDOE_04007 0.0 ywqJ S Pre-toxin TG
HHMJEDOE_04010 6.1e-61
HHMJEDOE_04011 2e-124 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HHMJEDOE_04012 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
HHMJEDOE_04013 7.1e-104 ywrB P Chromate transporter
HHMJEDOE_04014 4e-81 ywrC K Transcriptional regulator
HHMJEDOE_04015 2.2e-290 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HHMJEDOE_04016 4.1e-27 S Domain of unknown function (DUF4181)
HHMJEDOE_04017 1.1e-104 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HHMJEDOE_04018 3.8e-12
HHMJEDOE_04019 6.7e-201 cotH M Spore Coat
HHMJEDOE_04020 8.8e-143 alsR K LysR substrate binding domain
HHMJEDOE_04021 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHMJEDOE_04022 2.2e-142 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HHMJEDOE_04023 1e-90 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HHMJEDOE_04024 9.2e-44 ywsA S Protein of unknown function (DUF3892)
HHMJEDOE_04025 5.6e-84 batE T Sh3 type 3 domain protein
HHMJEDOE_04026 6.5e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HHMJEDOE_04027 8.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
HHMJEDOE_04028 1.1e-265 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HHMJEDOE_04029 4.2e-60 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHMJEDOE_04030 8.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHMJEDOE_04031 3.7e-166 rbsR K transcriptional
HHMJEDOE_04032 6.7e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HHMJEDOE_04033 8.6e-70 pgsC S biosynthesis protein
HHMJEDOE_04034 1.7e-215 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HHMJEDOE_04035 5.8e-19 ywtC
HHMJEDOE_04036 1.5e-228 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HHMJEDOE_04037 6.1e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HHMJEDOE_04038 8.3e-142 ywtF K Transcriptional regulator
HHMJEDOE_04039 5.6e-245 ywtG EGP Major facilitator Superfamily
HHMJEDOE_04040 1.8e-193 gerAC S Spore germination protein
HHMJEDOE_04041 8.6e-188 gerBB E Spore germination protein
HHMJEDOE_04042 2.2e-252 gerBA EG Spore germination protein
HHMJEDOE_04043 4.6e-182 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HHMJEDOE_04044 4e-199 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHMJEDOE_04045 1.7e-191 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHMJEDOE_04046 2.7e-91 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHMJEDOE_04047 2.1e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HHMJEDOE_04048 4.5e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HHMJEDOE_04049 9.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHMJEDOE_04050 6e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHMJEDOE_04051 3.6e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HHMJEDOE_04052 1.5e-134 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HHMJEDOE_04053 4.7e-119 ggaA M Glycosyltransferase like family 2
HHMJEDOE_04054 2.9e-80
HHMJEDOE_04055 6.7e-138 M Glycosyltransferase like family 2
HHMJEDOE_04056 1e-168 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHMJEDOE_04057 4.2e-131 tagG GM Transport permease protein
HHMJEDOE_04058 6.2e-264 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHMJEDOE_04059 1e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHMJEDOE_04060 1.7e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HHMJEDOE_04061 2.5e-97 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HHMJEDOE_04062 6.2e-88 M Glycosyltransferase like family 2
HHMJEDOE_04063 2.9e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHMJEDOE_04064 4.4e-153 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HHMJEDOE_04065 1.2e-12
HHMJEDOE_04066 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HHMJEDOE_04067 1.9e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HHMJEDOE_04068 8.4e-98 M Glycosyltransferase like family 2
HHMJEDOE_04069 3.5e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HHMJEDOE_04070 1.7e-239 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HHMJEDOE_04071 5.7e-206 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HHMJEDOE_04072 6.7e-254 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HHMJEDOE_04073 1.9e-251 tuaE M Teichuronic acid biosynthesis protein
HHMJEDOE_04074 5.8e-110 tuaF M protein involved in exopolysaccharide biosynthesis
HHMJEDOE_04075 2.5e-138 tuaG GT2 M Glycosyltransferase like family 2
HHMJEDOE_04076 2.1e-224 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HHMJEDOE_04077 3.2e-179 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HHMJEDOE_04078 8.6e-159 yvhJ K Transcriptional regulator
HHMJEDOE_04079 5e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HHMJEDOE_04080 1.1e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HHMJEDOE_04081 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HHMJEDOE_04082 9.9e-152 degV S protein conserved in bacteria
HHMJEDOE_04083 1.7e-238 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HHMJEDOE_04084 2e-43 comFB S Late competence development protein ComFB
HHMJEDOE_04085 6.3e-115 comFC S Phosphoribosyl transferase domain
HHMJEDOE_04086 3.1e-69 yvyF S flagellar protein
HHMJEDOE_04087 7.5e-37 flgM KNU Negative regulator of flagellin synthesis
HHMJEDOE_04088 2.8e-74 flgN NOU FlgN protein
HHMJEDOE_04089 5.8e-251 flgK N flagellar hook-associated protein
HHMJEDOE_04090 8.9e-151 flgL N Belongs to the bacterial flagellin family
HHMJEDOE_04091 5.4e-45 yviE
HHMJEDOE_04092 2e-68 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HHMJEDOE_04093 2.2e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HHMJEDOE_04094 5e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHMJEDOE_04095 2.2e-54 flaG N flagellar protein FlaG
HHMJEDOE_04096 3.2e-254 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HHMJEDOE_04097 1e-66 fliS N flagellar protein FliS
HHMJEDOE_04098 1.9e-08 fliT S bacterial-type flagellum organization
HHMJEDOE_04099 9.2e-65
HHMJEDOE_04101 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHMJEDOE_04102 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHMJEDOE_04103 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHMJEDOE_04104 1.5e-136 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HHMJEDOE_04105 1.5e-53 cccB C COG2010 Cytochrome c, mono- and diheme variants
HHMJEDOE_04106 4.3e-121 ftsE D cell division ATP-binding protein FtsE
HHMJEDOE_04107 3.9e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HHMJEDOE_04108 2.9e-260 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HHMJEDOE_04109 4.5e-55 swrA S Swarming motility protein
HHMJEDOE_04110 4.4e-206 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HHMJEDOE_04111 1.6e-220 yvkA EGP Major facilitator Superfamily
HHMJEDOE_04112 4.4e-95 yvkB K Transcriptional regulator
HHMJEDOE_04113 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HHMJEDOE_04115 1.2e-30 csbA S protein conserved in bacteria
HHMJEDOE_04116 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHMJEDOE_04117 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHMJEDOE_04118 3.9e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HHMJEDOE_04119 5.3e-31 yvkN
HHMJEDOE_04120 4.4e-47 yvlA
HHMJEDOE_04121 5.6e-163 yvlB S Putative adhesin
HHMJEDOE_04122 1.3e-25 pspB KT PspC domain
HHMJEDOE_04123 1.2e-50 yvlD S Membrane
HHMJEDOE_04124 6e-44 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)