ORF_ID e_value Gene_name EC_number CAZy COGs Description
KMKKNLJM_00001 2.3e-90 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_00002 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KMKKNLJM_00003 1.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
KMKKNLJM_00004 2.3e-246 yoeA V MATE efflux family protein
KMKKNLJM_00005 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KMKKNLJM_00007 2.2e-96 L Integrase
KMKKNLJM_00008 3e-34 yoeD G Helix-turn-helix domain
KMKKNLJM_00009 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KMKKNLJM_00010 4.8e-154 gltR1 K Transcriptional regulator
KMKKNLJM_00011 6.7e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMKKNLJM_00012 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KMKKNLJM_00013 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KMKKNLJM_00014 7.8e-155 gltC K Transcriptional regulator
KMKKNLJM_00015 1.5e-203 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMKKNLJM_00016 6.2e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMKKNLJM_00017 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KMKKNLJM_00018 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_00019 7.7e-38 yoxC S Bacterial protein of unknown function (DUF948)
KMKKNLJM_00020 1e-134 yoxB
KMKKNLJM_00021 1.7e-93 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMKKNLJM_00022 1.5e-233 yoaB EGP Major facilitator Superfamily
KMKKNLJM_00023 5.1e-281 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KMKKNLJM_00024 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMKKNLJM_00025 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMKKNLJM_00026 1.1e-33 yoaF
KMKKNLJM_00027 6.5e-08 ywlA S Uncharacterised protein family (UPF0715)
KMKKNLJM_00028 7.7e-13
KMKKNLJM_00029 1.1e-36 S Protein of unknown function (DUF4025)
KMKKNLJM_00030 4.4e-183 mcpU NT methyl-accepting chemotaxis protein
KMKKNLJM_00031 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KMKKNLJM_00032 1.1e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KMKKNLJM_00033 9.8e-110 yoaK S Membrane
KMKKNLJM_00034 4.7e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KMKKNLJM_00035 1.2e-131 yoqW S Belongs to the SOS response-associated peptidase family
KMKKNLJM_00038 4.6e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
KMKKNLJM_00041 4e-84
KMKKNLJM_00042 7.1e-172 yoaR V vancomycin resistance protein
KMKKNLJM_00043 3.6e-74 yoaS S Protein of unknown function (DUF2975)
KMKKNLJM_00044 4.4e-30 yozG K Transcriptional regulator
KMKKNLJM_00045 8.2e-148 yoaT S Protein of unknown function (DUF817)
KMKKNLJM_00046 9.6e-158 yoaU K LysR substrate binding domain
KMKKNLJM_00047 3.7e-157 yijE EG EamA-like transporter family
KMKKNLJM_00048 1.6e-76 yoaW
KMKKNLJM_00049 1.6e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KMKKNLJM_00050 5.9e-166 bla 3.5.2.6 V beta-lactamase
KMKKNLJM_00054 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KMKKNLJM_00055 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KMKKNLJM_00057 6.2e-49 FG Scavenger mRNA decapping enzyme C-term binding
KMKKNLJM_00062 1.5e-09 ywlA S Uncharacterised protein family (UPF0715)
KMKKNLJM_00066 4.1e-54 S Tetratricopeptide repeat
KMKKNLJM_00067 9e-61 J tRNA cytidylyltransferase activity
KMKKNLJM_00068 2.6e-30 K Cro/C1-type HTH DNA-binding domain
KMKKNLJM_00069 1.1e-36 KLT RIO1 family
KMKKNLJM_00072 7.4e-121 isp O Subtilase family
KMKKNLJM_00073 6.8e-76
KMKKNLJM_00074 7.4e-23 1.15.1.2 C Rubrerythrin
KMKKNLJM_00076 6.9e-54 yoqW S Belongs to the SOS response-associated peptidase family
KMKKNLJM_00077 1.8e-95 S aspartate phosphatase
KMKKNLJM_00079 9e-19
KMKKNLJM_00080 4.4e-17 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KMKKNLJM_00081 2e-100 yokH G SMI1 / KNR4 family
KMKKNLJM_00082 6.8e-278 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KMKKNLJM_00083 4.2e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KMKKNLJM_00084 1.1e-135 yobQ K helix_turn_helix, arabinose operon control protein
KMKKNLJM_00085 5.3e-141 yobR 2.3.1.1 J FR47-like protein
KMKKNLJM_00086 1.5e-95 yobS K Transcriptional regulator
KMKKNLJM_00087 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KMKKNLJM_00088 3.2e-86 yobU K Bacterial transcription activator, effector binding domain
KMKKNLJM_00089 1.5e-172 yobV K WYL domain
KMKKNLJM_00090 2e-92 yobW
KMKKNLJM_00091 1e-51 czrA K transcriptional
KMKKNLJM_00092 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMKKNLJM_00093 1.5e-92 yozB S membrane
KMKKNLJM_00094 1.1e-144
KMKKNLJM_00095 1.5e-91 yocC
KMKKNLJM_00096 7.9e-185 yocD 3.4.17.13 V peptidase S66
KMKKNLJM_00097 1.2e-202 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KMKKNLJM_00098 7.1e-198 desK 2.7.13.3 T Histidine kinase
KMKKNLJM_00099 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_00100 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KMKKNLJM_00101 0.0 recQ 3.6.4.12 L DNA helicase
KMKKNLJM_00102 2.3e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMKKNLJM_00103 3.3e-83 dksA T general stress protein
KMKKNLJM_00104 5.4e-53 yocL
KMKKNLJM_00105 6.2e-32
KMKKNLJM_00106 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KMKKNLJM_00107 1.1e-40 yozN
KMKKNLJM_00108 1.9e-36 yocN
KMKKNLJM_00109 4.2e-56 yozO S Bacterial PH domain
KMKKNLJM_00110 2.7e-31 yozC
KMKKNLJM_00111 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KMKKNLJM_00112 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KMKKNLJM_00113 6e-165 sodA 1.15.1.1 P Superoxide dismutase
KMKKNLJM_00114 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMKKNLJM_00115 8.6e-168 yocS S -transporter
KMKKNLJM_00116 1.6e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KMKKNLJM_00117 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KMKKNLJM_00118 0.0 yojO P Von Willebrand factor
KMKKNLJM_00119 3.2e-161 yojN S ATPase family associated with various cellular activities (AAA)
KMKKNLJM_00120 1.9e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KMKKNLJM_00121 7.4e-196 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMKKNLJM_00122 3.4e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KMKKNLJM_00123 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMKKNLJM_00125 4.2e-245 norM V Multidrug efflux pump
KMKKNLJM_00126 1.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMKKNLJM_00127 2.1e-125 yojG S deacetylase
KMKKNLJM_00128 2.2e-60 yojF S Protein of unknown function (DUF1806)
KMKKNLJM_00129 1.5e-43
KMKKNLJM_00130 5.6e-161 rarD S -transporter
KMKKNLJM_00131 1.7e-60 yozR S COG0071 Molecular chaperone (small heat shock protein)
KMKKNLJM_00132 3.4e-09
KMKKNLJM_00133 1.9e-205 gntP EG COG2610 H gluconate symporter and related permeases
KMKKNLJM_00134 8e-64 yodA S tautomerase
KMKKNLJM_00135 4.4e-55 yodB K transcriptional
KMKKNLJM_00136 1.4e-107 yodC C nitroreductase
KMKKNLJM_00137 2.1e-111 mhqD S Carboxylesterase
KMKKNLJM_00138 8.4e-173 yodE E COG0346 Lactoylglutathione lyase and related lyases
KMKKNLJM_00139 6.2e-28 S Protein of unknown function (DUF3311)
KMKKNLJM_00140 6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMKKNLJM_00141 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KMKKNLJM_00142 6.3e-128 yodH Q Methyltransferase
KMKKNLJM_00143 1.5e-23 yodI
KMKKNLJM_00144 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KMKKNLJM_00145 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KMKKNLJM_00146 5.3e-09
KMKKNLJM_00147 3.6e-54 yodL S YodL-like
KMKKNLJM_00148 2e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KMKKNLJM_00149 2.8e-24 yozD S YozD-like protein
KMKKNLJM_00151 6e-123 yodN
KMKKNLJM_00152 1.4e-36 yozE S Belongs to the UPF0346 family
KMKKNLJM_00153 2.9e-47 yokU S YokU-like protein, putative antitoxin
KMKKNLJM_00154 8.8e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KMKKNLJM_00155 8.8e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KMKKNLJM_00156 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
KMKKNLJM_00157 3.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMKKNLJM_00158 1.7e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMKKNLJM_00159 1.2e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMKKNLJM_00161 1.2e-143 yiiD K acetyltransferase
KMKKNLJM_00162 4.7e-254 cgeD M maturation of the outermost layer of the spore
KMKKNLJM_00163 2.7e-35 cgeC
KMKKNLJM_00164 1.2e-65 cgeA
KMKKNLJM_00165 6.9e-186 cgeB S Spore maturation protein
KMKKNLJM_00166 2.2e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KMKKNLJM_00167 8.1e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
KMKKNLJM_00169 5.4e-104 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMKKNLJM_00170 2.4e-10 K Cro/C1-type HTH DNA-binding domain
KMKKNLJM_00175 5.2e-70 yhdJ 2.1.1.72 L DNA methylase
KMKKNLJM_00183 6.5e-164 S Calcineurin-like phosphoesterase
KMKKNLJM_00184 2.5e-30 sspB S spore protein
KMKKNLJM_00187 7e-36
KMKKNLJM_00189 2.5e-08 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMKKNLJM_00190 3e-17 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMKKNLJM_00191 2.8e-162 S Thymidylate synthase
KMKKNLJM_00194 4.9e-15 vanZ V COG4767 Glycopeptide antibiotics resistance protein
KMKKNLJM_00195 2.5e-74 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KMKKNLJM_00196 2.4e-09
KMKKNLJM_00197 6.1e-38 O Glutaredoxin
KMKKNLJM_00198 1.9e-186 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMKKNLJM_00200 0.0 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
KMKKNLJM_00201 6.2e-64 S NrdI Flavodoxin like
KMKKNLJM_00214 4.6e-25 S hydrolase activity
KMKKNLJM_00217 1.5e-13
KMKKNLJM_00222 7.5e-255 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KMKKNLJM_00227 5.4e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
KMKKNLJM_00232 1.6e-102 DR0488 S protein conserved in bacteria
KMKKNLJM_00233 0.0 S Bacterial DNA polymerase III alpha subunit
KMKKNLJM_00234 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KMKKNLJM_00235 4.2e-222 L DNA primase activity
KMKKNLJM_00236 1e-284 3.6.4.12 J DnaB-like helicase C terminal domain
KMKKNLJM_00237 9.9e-85
KMKKNLJM_00238 5.4e-178 L AAA domain
KMKKNLJM_00239 1.6e-155
KMKKNLJM_00242 5.5e-101 rssA S esterase of the alpha-beta hydrolase superfamily
KMKKNLJM_00244 3.6e-26
KMKKNLJM_00246 9.4e-129 yoqW S Belongs to the SOS response-associated peptidase family
KMKKNLJM_00247 1.7e-145 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
KMKKNLJM_00248 7.8e-13 S Hypothetical protein (DUF2513)
KMKKNLJM_00250 1.6e-72
KMKKNLJM_00252 1.4e-38
KMKKNLJM_00253 4.4e-94 S Protein of unknown function (DUF1273)
KMKKNLJM_00257 6.6e-12 K AntA/AntB antirepressor
KMKKNLJM_00260 4e-08 S YopX protein
KMKKNLJM_00265 1.1e-33 K Transcriptional regulator
KMKKNLJM_00266 2.1e-177
KMKKNLJM_00267 1.1e-259 S DNA-sulfur modification-associated
KMKKNLJM_00268 8.9e-198 L Belongs to the 'phage' integrase family
KMKKNLJM_00273 7.3e-105
KMKKNLJM_00275 4.9e-31 yoaF
KMKKNLJM_00276 2e-10
KMKKNLJM_00277 7.3e-35
KMKKNLJM_00278 1.4e-30
KMKKNLJM_00279 4.1e-13
KMKKNLJM_00287 1e-11 L DNA helicase
KMKKNLJM_00289 7.8e-30 K Cro/C1-type HTH DNA-binding domain
KMKKNLJM_00296 1e-234
KMKKNLJM_00300 0.0 S RNA-directed RNA polymerase activity
KMKKNLJM_00301 1.6e-14 L GIY-YIG type nucleases (URI domain)
KMKKNLJM_00302 4.7e-90
KMKKNLJM_00303 2.5e-35 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMKKNLJM_00305 4.3e-209 S Calcineurin-like phosphoesterase superfamily domain
KMKKNLJM_00308 2.2e-17
KMKKNLJM_00309 3.7e-108
KMKKNLJM_00310 3.1e-18
KMKKNLJM_00311 2.1e-35
KMKKNLJM_00313 3.3e-70
KMKKNLJM_00316 1.8e-68
KMKKNLJM_00317 2.6e-91
KMKKNLJM_00318 2.4e-130
KMKKNLJM_00319 2.3e-89
KMKKNLJM_00322 3.8e-52
KMKKNLJM_00323 3.3e-31
KMKKNLJM_00326 3.1e-57
KMKKNLJM_00327 8.9e-61
KMKKNLJM_00328 1.2e-191 xerH A Belongs to the 'phage' integrase family
KMKKNLJM_00331 2.4e-46
KMKKNLJM_00332 0.0 S peptidoglycan catabolic process
KMKKNLJM_00333 2.1e-84 S Phage tail protein
KMKKNLJM_00334 7.8e-304 S Pfam Transposase IS66
KMKKNLJM_00335 4.7e-98
KMKKNLJM_00336 6.4e-57 S outer membrane
KMKKNLJM_00337 5.5e-75 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KMKKNLJM_00339 9.2e-37 S Bacteriophage holin
KMKKNLJM_00340 1.9e-190 S aspartate phosphatase
KMKKNLJM_00342 2.2e-232 S impB/mucB/samB family C-terminal domain
KMKKNLJM_00343 5.6e-50 S YolD-like protein
KMKKNLJM_00345 4.3e-36
KMKKNLJM_00347 4e-09 S Domain of unknown function (DUF4879)
KMKKNLJM_00349 2.8e-99 J Acetyltransferase (GNAT) domain
KMKKNLJM_00350 7.6e-28 yokK S SMI1 / KNR4 family
KMKKNLJM_00351 8.2e-68 yokK S SMI1 / KNR4 family
KMKKNLJM_00352 1.9e-94 yokJ S SMI1 / KNR4 family (SUKH-1)
KMKKNLJM_00353 2.1e-302 UW nuclease activity
KMKKNLJM_00354 2e-65 G SMI1-KNR4 cell-wall
KMKKNLJM_00355 1e-35
KMKKNLJM_00356 2.3e-106 yokF 3.1.31.1 L RNA catabolic process
KMKKNLJM_00359 2.2e-235 yokA L Recombinase
KMKKNLJM_00360 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
KMKKNLJM_00361 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KMKKNLJM_00362 1.7e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KMKKNLJM_00363 1.6e-70 ypoP K transcriptional
KMKKNLJM_00364 2.2e-222 mepA V MATE efflux family protein
KMKKNLJM_00365 5.5e-29 ypmT S Uncharacterized ympT
KMKKNLJM_00366 1.9e-98 ypmS S protein conserved in bacteria
KMKKNLJM_00367 4.8e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KMKKNLJM_00368 1.2e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KMKKNLJM_00369 3.1e-40 ypmP S Protein of unknown function (DUF2535)
KMKKNLJM_00370 2.8e-243 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KMKKNLJM_00371 2.3e-184 pspF K Transcriptional regulator
KMKKNLJM_00372 4.2e-110 hlyIII S protein, Hemolysin III
KMKKNLJM_00373 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMKKNLJM_00374 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KMKKNLJM_00375 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMKKNLJM_00376 1.2e-91 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KMKKNLJM_00377 4.3e-112 ypjP S YpjP-like protein
KMKKNLJM_00378 2.9e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KMKKNLJM_00379 1.7e-75 yphP S Belongs to the UPF0403 family
KMKKNLJM_00380 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KMKKNLJM_00381 1.5e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KMKKNLJM_00382 3.2e-107 ypgQ S phosphohydrolase
KMKKNLJM_00383 4.9e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KMKKNLJM_00384 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KMKKNLJM_00386 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KMKKNLJM_00387 7.9e-31 cspD K Cold-shock protein
KMKKNLJM_00388 3.8e-16 degR
KMKKNLJM_00389 8.1e-31 S Protein of unknown function (DUF2564)
KMKKNLJM_00390 1.1e-28 ypeQ S Zinc-finger
KMKKNLJM_00391 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KMKKNLJM_00392 1e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KMKKNLJM_00393 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
KMKKNLJM_00395 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KMKKNLJM_00396 2e-07
KMKKNLJM_00397 1e-38 ypbS S Protein of unknown function (DUF2533)
KMKKNLJM_00398 0.0 ypbR S Dynamin family
KMKKNLJM_00400 5.1e-87 ypbQ S protein conserved in bacteria
KMKKNLJM_00401 3.5e-205 bcsA Q Naringenin-chalcone synthase
KMKKNLJM_00402 2.1e-225 pbuX F xanthine
KMKKNLJM_00403 2.6e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KMKKNLJM_00404 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KMKKNLJM_00405 2.1e-169 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KMKKNLJM_00406 1.7e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KMKKNLJM_00407 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KMKKNLJM_00408 1.3e-185 ptxS K transcriptional
KMKKNLJM_00409 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KMKKNLJM_00410 1.8e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_00411 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KMKKNLJM_00413 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KMKKNLJM_00414 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KMKKNLJM_00415 9.7e-92 ypsA S Belongs to the UPF0398 family
KMKKNLJM_00416 5.6e-236 yprB L RNase_H superfamily
KMKKNLJM_00417 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KMKKNLJM_00418 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KMKKNLJM_00419 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
KMKKNLJM_00420 1e-47 yppG S YppG-like protein
KMKKNLJM_00422 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
KMKKNLJM_00425 1.8e-186 yppC S Protein of unknown function (DUF2515)
KMKKNLJM_00426 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KMKKNLJM_00427 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KMKKNLJM_00428 1.8e-92 ypoC
KMKKNLJM_00429 8.3e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KMKKNLJM_00430 5.7e-129 dnaD L DNA replication protein DnaD
KMKKNLJM_00431 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KMKKNLJM_00432 6.3e-221 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KMKKNLJM_00433 2.2e-79 ypmB S protein conserved in bacteria
KMKKNLJM_00434 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KMKKNLJM_00435 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KMKKNLJM_00436 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KMKKNLJM_00437 6.8e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KMKKNLJM_00438 5.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KMKKNLJM_00439 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KMKKNLJM_00440 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KMKKNLJM_00441 7.7e-208 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KMKKNLJM_00442 4.9e-128 bshB1 S proteins, LmbE homologs
KMKKNLJM_00443 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KMKKNLJM_00444 9.1e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KMKKNLJM_00445 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KMKKNLJM_00446 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KMKKNLJM_00447 1.9e-141 ypjB S sporulation protein
KMKKNLJM_00448 1.1e-99 ypjA S membrane
KMKKNLJM_00449 4.8e-145 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KMKKNLJM_00450 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KMKKNLJM_00451 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KMKKNLJM_00452 1.2e-76 ypiF S Protein of unknown function (DUF2487)
KMKKNLJM_00453 1.1e-98 ypiB S Belongs to the UPF0302 family
KMKKNLJM_00454 5.9e-233 S COG0457 FOG TPR repeat
KMKKNLJM_00455 1.1e-234 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KMKKNLJM_00456 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KMKKNLJM_00457 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KMKKNLJM_00458 2.1e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KMKKNLJM_00459 1.3e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KMKKNLJM_00460 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KMKKNLJM_00461 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KMKKNLJM_00462 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KMKKNLJM_00463 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMKKNLJM_00464 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KMKKNLJM_00465 2.2e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KMKKNLJM_00466 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KMKKNLJM_00467 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KMKKNLJM_00468 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KMKKNLJM_00469 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMKKNLJM_00470 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KMKKNLJM_00471 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KMKKNLJM_00472 5e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KMKKNLJM_00473 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KMKKNLJM_00474 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KMKKNLJM_00475 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KMKKNLJM_00476 6.6e-136 yphF
KMKKNLJM_00477 1.2e-18 yphE S Protein of unknown function (DUF2768)
KMKKNLJM_00478 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KMKKNLJM_00479 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KMKKNLJM_00480 2.1e-28 ypzH
KMKKNLJM_00481 3.3e-161 seaA S YIEGIA protein
KMKKNLJM_00482 6.7e-102 yphA
KMKKNLJM_00483 1e-07 S YpzI-like protein
KMKKNLJM_00484 7.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KMKKNLJM_00485 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KMKKNLJM_00486 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KMKKNLJM_00487 4.1e-23 S Family of unknown function (DUF5359)
KMKKNLJM_00488 3.9e-111 ypfA M Flagellar protein YcgR
KMKKNLJM_00489 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KMKKNLJM_00490 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KMKKNLJM_00491 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
KMKKNLJM_00492 2.4e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KMKKNLJM_00493 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMKKNLJM_00494 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMKKNLJM_00495 1.3e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
KMKKNLJM_00496 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KMKKNLJM_00497 8.6e-75 ypbE M Lysin motif
KMKKNLJM_00498 1.1e-99 ypbD S metal-dependent membrane protease
KMKKNLJM_00499 9.2e-286 recQ 3.6.4.12 L DNA helicase
KMKKNLJM_00500 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
KMKKNLJM_00501 4.7e-41 fer C Ferredoxin
KMKKNLJM_00502 1e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KMKKNLJM_00503 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMKKNLJM_00504 1e-131 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KMKKNLJM_00505 1.3e-196 rsiX
KMKKNLJM_00506 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_00507 0.0 resE 2.7.13.3 T Histidine kinase
KMKKNLJM_00508 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_00509 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KMKKNLJM_00510 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KMKKNLJM_00511 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KMKKNLJM_00512 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KMKKNLJM_00513 1.9e-87 spmB S Spore maturation protein
KMKKNLJM_00514 3.5e-103 spmA S Spore maturation protein
KMKKNLJM_00515 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KMKKNLJM_00516 4e-98 ypuI S Protein of unknown function (DUF3907)
KMKKNLJM_00517 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KMKKNLJM_00518 4.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KMKKNLJM_00519 2.3e-90 ypuF S Domain of unknown function (DUF309)
KMKKNLJM_00520 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_00521 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KMKKNLJM_00522 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KMKKNLJM_00523 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
KMKKNLJM_00524 1.1e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KMKKNLJM_00525 7.8e-55 ypuD
KMKKNLJM_00526 1.4e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KMKKNLJM_00527 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KMKKNLJM_00528 3.1e-16 S SNARE associated Golgi protein
KMKKNLJM_00531 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KMKKNLJM_00532 3.6e-149 ypuA S Secreted protein
KMKKNLJM_00533 1.7e-254 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KMKKNLJM_00534 1.4e-273 spoVAF EG Stage V sporulation protein AF
KMKKNLJM_00535 1.4e-110 spoVAEA S stage V sporulation protein
KMKKNLJM_00536 2.2e-57 spoVAEB S stage V sporulation protein
KMKKNLJM_00537 9e-192 spoVAD I Stage V sporulation protein AD
KMKKNLJM_00538 2.3e-78 spoVAC S stage V sporulation protein AC
KMKKNLJM_00539 1e-67 spoVAB S Stage V sporulation protein AB
KMKKNLJM_00540 9.6e-112 spoVAA S Stage V sporulation protein AA
KMKKNLJM_00541 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_00542 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KMKKNLJM_00543 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KMKKNLJM_00544 3.4e-211 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KMKKNLJM_00545 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KMKKNLJM_00546 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KMKKNLJM_00547 2.6e-166 xerD L recombinase XerD
KMKKNLJM_00548 3.7e-37 S Protein of unknown function (DUF4227)
KMKKNLJM_00549 2.4e-80 fur P Belongs to the Fur family
KMKKNLJM_00550 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KMKKNLJM_00551 1.2e-29 yqkK
KMKKNLJM_00552 5.5e-242 mleA 1.1.1.38 C malic enzyme
KMKKNLJM_00553 1.1e-227 mleN C Na H antiporter
KMKKNLJM_00554 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KMKKNLJM_00555 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
KMKKNLJM_00556 4.5e-58 ansR K Transcriptional regulator
KMKKNLJM_00557 5.1e-223 yqxK 3.6.4.12 L DNA helicase
KMKKNLJM_00558 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KMKKNLJM_00560 1.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KMKKNLJM_00561 1.3e-10 yqkE S Protein of unknown function (DUF3886)
KMKKNLJM_00562 1.9e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KMKKNLJM_00563 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KMKKNLJM_00564 2.8e-54 yqkB S Belongs to the HesB IscA family
KMKKNLJM_00565 1.3e-193 yqkA K GrpB protein
KMKKNLJM_00566 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KMKKNLJM_00567 1.1e-86 yqjY K acetyltransferase
KMKKNLJM_00568 2.2e-49 S YolD-like protein
KMKKNLJM_00569 2.9e-237 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMKKNLJM_00571 1.1e-220 yqjV G Major Facilitator Superfamily
KMKKNLJM_00573 5.7e-70 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_00574 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KMKKNLJM_00575 1e-259 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KMKKNLJM_00576 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_00577 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KMKKNLJM_00578 7.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMKKNLJM_00579 2.3e-311 rocB E arginine degradation protein
KMKKNLJM_00580 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KMKKNLJM_00581 4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMKKNLJM_00582 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMKKNLJM_00583 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KMKKNLJM_00584 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KMKKNLJM_00585 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMKKNLJM_00586 6.8e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KMKKNLJM_00587 4.5e-24 yqzJ
KMKKNLJM_00588 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMKKNLJM_00589 5.4e-138 yqjF S Uncharacterized conserved protein (COG2071)
KMKKNLJM_00590 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KMKKNLJM_00591 2e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMKKNLJM_00592 3.2e-74 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KMKKNLJM_00594 3e-98 yqjB S protein conserved in bacteria
KMKKNLJM_00595 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
KMKKNLJM_00596 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMKKNLJM_00597 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KMKKNLJM_00598 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
KMKKNLJM_00599 1.2e-76 yqiW S Belongs to the UPF0403 family
KMKKNLJM_00600 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMKKNLJM_00601 5.1e-207 norA EGP Major facilitator Superfamily
KMKKNLJM_00602 2.6e-152 bmrR K helix_turn_helix, mercury resistance
KMKKNLJM_00603 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMKKNLJM_00604 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMKKNLJM_00605 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMKKNLJM_00606 2.2e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMKKNLJM_00607 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KMKKNLJM_00608 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMKKNLJM_00609 1e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KMKKNLJM_00610 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KMKKNLJM_00611 4e-34 yqzF S Protein of unknown function (DUF2627)
KMKKNLJM_00612 1.3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KMKKNLJM_00613 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KMKKNLJM_00614 1.3e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KMKKNLJM_00615 1.2e-208 mmgC I acyl-CoA dehydrogenase
KMKKNLJM_00616 8.3e-154 hbdA 1.1.1.157 I Dehydrogenase
KMKKNLJM_00617 2.6e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
KMKKNLJM_00618 1.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMKKNLJM_00619 1.6e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KMKKNLJM_00620 6e-27
KMKKNLJM_00621 1.4e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KMKKNLJM_00623 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KMKKNLJM_00624 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KMKKNLJM_00625 6.5e-307 recN L May be involved in recombinational repair of damaged DNA
KMKKNLJM_00626 8.6e-78 argR K Regulates arginine biosynthesis genes
KMKKNLJM_00627 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KMKKNLJM_00628 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KMKKNLJM_00629 5e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KMKKNLJM_00630 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMKKNLJM_00631 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KMKKNLJM_00632 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KMKKNLJM_00633 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KMKKNLJM_00634 2.1e-67 yqhY S protein conserved in bacteria
KMKKNLJM_00635 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KMKKNLJM_00636 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KMKKNLJM_00637 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KMKKNLJM_00638 4.2e-108 spoIIIAG S stage III sporulation protein AG
KMKKNLJM_00639 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KMKKNLJM_00640 6.4e-197 spoIIIAE S stage III sporulation protein AE
KMKKNLJM_00641 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KMKKNLJM_00642 7.6e-29 spoIIIAC S stage III sporulation protein AC
KMKKNLJM_00643 3.2e-84 spoIIIAB S Stage III sporulation protein
KMKKNLJM_00644 1e-170 spoIIIAA S stage III sporulation protein AA
KMKKNLJM_00645 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KMKKNLJM_00646 2.1e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KMKKNLJM_00647 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KMKKNLJM_00648 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KMKKNLJM_00649 6.6e-93 yqhR S Conserved membrane protein YqhR
KMKKNLJM_00650 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
KMKKNLJM_00651 2.2e-61 yqhP
KMKKNLJM_00652 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
KMKKNLJM_00653 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KMKKNLJM_00654 9.8e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KMKKNLJM_00655 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KMKKNLJM_00656 2.6e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMKKNLJM_00657 1.7e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KMKKNLJM_00658 6.9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KMKKNLJM_00659 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMKKNLJM_00660 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KMKKNLJM_00661 1.2e-24 sinI S Anti-repressor SinI
KMKKNLJM_00662 1e-54 sinR K transcriptional
KMKKNLJM_00663 1.9e-141 tasA S Cell division protein FtsN
KMKKNLJM_00664 6.7e-59 sipW 3.4.21.89 U Signal peptidase
KMKKNLJM_00665 1.9e-109 yqxM
KMKKNLJM_00666 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KMKKNLJM_00667 1.4e-26 yqzE S YqzE-like protein
KMKKNLJM_00668 9.8e-43 S ComG operon protein 7
KMKKNLJM_00669 1.6e-48 comGF U Putative Competence protein ComGF
KMKKNLJM_00670 9e-59 comGE
KMKKNLJM_00671 4.9e-70 gspH NU protein transport across the cell outer membrane
KMKKNLJM_00672 3e-47 comGC U Required for transformation and DNA binding
KMKKNLJM_00673 2.8e-172 comGB NU COG1459 Type II secretory pathway, component PulF
KMKKNLJM_00674 1.2e-199 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KMKKNLJM_00676 8.8e-173 corA P Mg2 transporter protein
KMKKNLJM_00677 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KMKKNLJM_00678 8.6e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMKKNLJM_00680 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KMKKNLJM_00681 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KMKKNLJM_00682 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KMKKNLJM_00683 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KMKKNLJM_00684 6.9e-50 yqgV S Thiamine-binding protein
KMKKNLJM_00685 3.3e-197 yqgU
KMKKNLJM_00686 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KMKKNLJM_00687 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMKKNLJM_00688 1.2e-180 glcK 2.7.1.2 G Glucokinase
KMKKNLJM_00689 3.1e-33 yqgQ S Protein conserved in bacteria
KMKKNLJM_00690 4.1e-265 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KMKKNLJM_00691 5.6e-09 yqgO
KMKKNLJM_00692 2.2e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KMKKNLJM_00693 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KMKKNLJM_00694 6.2e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KMKKNLJM_00696 9.2e-51 yqzD
KMKKNLJM_00697 7e-75 yqzC S YceG-like family
KMKKNLJM_00698 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMKKNLJM_00699 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KMKKNLJM_00700 4.4e-158 pstA P Phosphate transport system permease
KMKKNLJM_00701 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KMKKNLJM_00702 6.2e-144 pstS P Phosphate
KMKKNLJM_00703 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KMKKNLJM_00704 2.5e-231 yqgE EGP Major facilitator superfamily
KMKKNLJM_00705 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KMKKNLJM_00706 4e-73 yqgC S protein conserved in bacteria
KMKKNLJM_00707 3.9e-131 yqgB S Protein of unknown function (DUF1189)
KMKKNLJM_00708 5.2e-47 yqfZ M LysM domain
KMKKNLJM_00709 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KMKKNLJM_00710 1.6e-61 yqfX S membrane
KMKKNLJM_00711 1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KMKKNLJM_00712 4.2e-77 zur P Belongs to the Fur family
KMKKNLJM_00713 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KMKKNLJM_00714 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KMKKNLJM_00715 4.4e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KMKKNLJM_00716 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KMKKNLJM_00718 1.3e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KMKKNLJM_00719 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KMKKNLJM_00720 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
KMKKNLJM_00721 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KMKKNLJM_00722 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KMKKNLJM_00723 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KMKKNLJM_00724 4.5e-88 yaiI S Belongs to the UPF0178 family
KMKKNLJM_00725 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KMKKNLJM_00726 4.5e-112 ccpN K CBS domain
KMKKNLJM_00727 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KMKKNLJM_00728 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KMKKNLJM_00729 6.9e-144 recO L Involved in DNA repair and RecF pathway recombination
KMKKNLJM_00730 8.4e-19 S YqzL-like protein
KMKKNLJM_00731 5.8e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KMKKNLJM_00732 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KMKKNLJM_00733 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KMKKNLJM_00734 1.1e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KMKKNLJM_00735 0.0 yqfF S membrane-associated HD superfamily hydrolase
KMKKNLJM_00737 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KMKKNLJM_00738 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KMKKNLJM_00739 2.7e-45 yqfC S sporulation protein YqfC
KMKKNLJM_00740 4.3e-23 yqfB
KMKKNLJM_00741 3.7e-121 yqfA S UPF0365 protein
KMKKNLJM_00742 5e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KMKKNLJM_00743 2.5e-61 yqeY S Yqey-like protein
KMKKNLJM_00744 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KMKKNLJM_00745 1.9e-156 yqeW P COG1283 Na phosphate symporter
KMKKNLJM_00746 1.3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KMKKNLJM_00747 1e-139 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KMKKNLJM_00748 5.4e-175 prmA J Methylates ribosomal protein L11
KMKKNLJM_00749 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KMKKNLJM_00750 0.0 dnaK O Heat shock 70 kDa protein
KMKKNLJM_00751 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KMKKNLJM_00752 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KMKKNLJM_00753 3.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
KMKKNLJM_00754 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KMKKNLJM_00755 3.6e-52 yqxA S Protein of unknown function (DUF3679)
KMKKNLJM_00756 1.5e-222 spoIIP M stage II sporulation protein P
KMKKNLJM_00757 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KMKKNLJM_00758 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KMKKNLJM_00759 5.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KMKKNLJM_00760 4.1e-15 S YqzM-like protein
KMKKNLJM_00761 0.0 comEC S Competence protein ComEC
KMKKNLJM_00762 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KMKKNLJM_00763 4.8e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KMKKNLJM_00764 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KMKKNLJM_00765 2.5e-138 yqeM Q Methyltransferase
KMKKNLJM_00766 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KMKKNLJM_00767 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KMKKNLJM_00768 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KMKKNLJM_00769 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KMKKNLJM_00770 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KMKKNLJM_00771 2e-213 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KMKKNLJM_00772 5.3e-95 yqeG S hydrolase of the HAD superfamily
KMKKNLJM_00774 1.4e-141 yqeF E GDSL-like Lipase/Acylhydrolase
KMKKNLJM_00775 4.6e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMKKNLJM_00776 1.8e-105 yqeD S SNARE associated Golgi protein
KMKKNLJM_00777 2.7e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KMKKNLJM_00778 6.3e-131 yqeB
KMKKNLJM_00779 2.4e-74 nucB M Deoxyribonuclease NucA/NucB
KMKKNLJM_00780 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_00781 2.4e-20 cisA2 L Recombinase
KMKKNLJM_00782 3.5e-73 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KMKKNLJM_00783 1.1e-215 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMKKNLJM_00784 1.8e-51 arsR K transcriptional
KMKKNLJM_00785 7.6e-44 arsR K ArsR family transcriptional regulator
KMKKNLJM_00786 5.7e-199 O Pyridine nucleotide-disulphide oxidoreductase
KMKKNLJM_00787 2.3e-37 2.3.1.183 M Acetyltransferase (GNAT) domain
KMKKNLJM_00788 7.7e-175 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMKKNLJM_00789 3.1e-112 C Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_00790 8.1e-19 K Bacterial regulatory proteins, tetR family
KMKKNLJM_00791 1.2e-122 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_00792 1.5e-197 OPR C NADH:flavin oxidoreductase / NADH oxidase family
KMKKNLJM_00793 2.1e-154 E TAP-like protein
KMKKNLJM_00794 1.5e-95 K QacR-like protein, C-terminal region
KMKKNLJM_00795 8.5e-118 1.1.1.1 C NADPH quinone reductase
KMKKNLJM_00796 2.3e-42 1.1.1.1 C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KMKKNLJM_00798 1.9e-206 S Aspartate phosphatase response regulator
KMKKNLJM_00799 4.1e-278 L nucleic acid phosphodiester bond hydrolysis
KMKKNLJM_00801 8.1e-104 yxxF EG EamA-like transporter family
KMKKNLJM_00802 2.5e-123 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KMKKNLJM_00803 4.8e-27 S phage terminase, large subunit
KMKKNLJM_00804 9.9e-77 yqaS L DNA packaging
KMKKNLJM_00808 1e-70 L Transposase
KMKKNLJM_00810 1.9e-27 yqaO S Phage-like element PBSX protein XtrA
KMKKNLJM_00811 1.8e-28 rusA L Endodeoxyribonuclease RusA
KMKKNLJM_00812 2.8e-19 tnpA1 L Helix-turn-helix domain of transposase family ISL3
KMKKNLJM_00813 3.9e-27 yosT L Bacterial transcription activator, effector binding domain
KMKKNLJM_00814 1.5e-42 cdo C cysteine dioxygenase type I
KMKKNLJM_00815 2e-94 yqaB E IrrE N-terminal-like domain
KMKKNLJM_00816 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_00817 2.8e-21 cisA2 L Recombinase
KMKKNLJM_00818 1.5e-97 ywrO S Flavodoxin-like fold
KMKKNLJM_00819 2.8e-79 S Protein of unknown function with HXXEE motif
KMKKNLJM_00821 2.7e-180 yjlA EG Putative multidrug resistance efflux transporter
KMKKNLJM_00822 1.9e-111 K COG1802 Transcriptional regulators
KMKKNLJM_00823 3.5e-111 yrkJ S membrane transporter protein
KMKKNLJM_00824 1.6e-35 yrkI O Belongs to the sulfur carrier protein TusA family
KMKKNLJM_00825 9.3e-206 yrkH P Rhodanese Homology Domain
KMKKNLJM_00826 3.4e-30 perX S DsrE/DsrF-like family
KMKKNLJM_00827 1.2e-97 yrkF OP Belongs to the sulfur carrier protein TusA family
KMKKNLJM_00828 5.2e-46 P Rhodanese Homology Domain
KMKKNLJM_00829 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
KMKKNLJM_00830 7.8e-39 yrkD S protein conserved in bacteria
KMKKNLJM_00831 7.6e-23
KMKKNLJM_00832 3.8e-107 yrkC G Cupin domain
KMKKNLJM_00833 3.1e-150 bltR K helix_turn_helix, mercury resistance
KMKKNLJM_00834 3.5e-211 blt EGP Major facilitator Superfamily
KMKKNLJM_00835 4.5e-82 bltD 2.3.1.57 K FR47-like protein
KMKKNLJM_00836 5.1e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KMKKNLJM_00837 3.9e-16 S YrzO-like protein
KMKKNLJM_00838 3.3e-164 yrdR EG EamA-like transporter family
KMKKNLJM_00839 1.9e-158 yrdQ K Transcriptional regulator
KMKKNLJM_00840 7.3e-197 trkA P Oxidoreductase
KMKKNLJM_00841 1.6e-150 czcD P COG1230 Co Zn Cd efflux system component
KMKKNLJM_00842 1.6e-228 brnQ E Component of the transport system for branched-chain amino acids
KMKKNLJM_00843 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KMKKNLJM_00844 3.3e-138 azlC E AzlC protein
KMKKNLJM_00845 1.4e-78 bkdR K helix_turn_helix ASNC type
KMKKNLJM_00846 1.2e-42 yrdF K ribonuclease inhibitor
KMKKNLJM_00847 1.6e-222 cypA C Cytochrome P450
KMKKNLJM_00848 5.4e-12 K Acetyltransferase (GNAT) family
KMKKNLJM_00850 2.6e-63 K Transcriptional regulator
KMKKNLJM_00851 1.1e-162 scrR K transcriptional
KMKKNLJM_00852 2.6e-228 msmE G Bacterial extracellular solute-binding protein
KMKKNLJM_00853 8.7e-149 msmF P Binding-protein-dependent transport system inner membrane component
KMKKNLJM_00854 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
KMKKNLJM_00855 2.1e-198 rafB P LacY proton/sugar symporter
KMKKNLJM_00856 3.9e-252 cscA 3.2.1.26 GH32 G invertase
KMKKNLJM_00857 4.2e-123 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
KMKKNLJM_00858 2.1e-73 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
KMKKNLJM_00859 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
KMKKNLJM_00860 4e-55 S Protein of unknown function (DUF2568)
KMKKNLJM_00862 3.2e-89 yrdA S DinB family
KMKKNLJM_00863 5e-167 aadK G Streptomycin adenylyltransferase
KMKKNLJM_00864 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KMKKNLJM_00865 2.4e-133 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KMKKNLJM_00866 1.6e-123 yrpD S Domain of unknown function, YrpD
KMKKNLJM_00867 1.9e-98 flr S Flavin reductase like domain
KMKKNLJM_00868 6.1e-117 bmrR K helix_turn_helix, mercury resistance
KMKKNLJM_00869 5.6e-50 yjbR S YjbR
KMKKNLJM_00870 3e-115 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KMKKNLJM_00871 2.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_00872 1.9e-186 yrpG C Aldo/keto reductase family
KMKKNLJM_00873 2.1e-154 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KMKKNLJM_00874 6.4e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_00875 1.8e-150 S Alpha beta hydrolase
KMKKNLJM_00876 2.2e-60 T sh3 domain protein
KMKKNLJM_00877 5.4e-61 T sh3 domain protein
KMKKNLJM_00879 3e-63 E Glyoxalase-like domain
KMKKNLJM_00880 2.6e-36 yraG
KMKKNLJM_00881 6.4e-63 yraF M Spore coat protein
KMKKNLJM_00882 5.1e-220 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMKKNLJM_00883 7.5e-26 yraE
KMKKNLJM_00884 3.3e-49 yraD M Spore coat protein
KMKKNLJM_00885 4.3e-47 yraB K helix_turn_helix, mercury resistance
KMKKNLJM_00886 2.8e-196 adhA 1.1.1.1 C alcohol dehydrogenase
KMKKNLJM_00887 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KMKKNLJM_00888 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KMKKNLJM_00889 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KMKKNLJM_00890 2.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KMKKNLJM_00891 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KMKKNLJM_00892 1.5e-74 levD 2.7.1.202 G PTS system fructose IIA component
KMKKNLJM_00893 0.0 levR K PTS system fructose IIA component
KMKKNLJM_00894 6.6e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_00895 1.1e-105 yrhP E LysE type translocator
KMKKNLJM_00896 7e-150 yrhO K Archaeal transcriptional regulator TrmB
KMKKNLJM_00897 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_00898 1e-148 rsiV S Protein of unknown function (DUF3298)
KMKKNLJM_00899 0.0 yrhL I Acyltransferase family
KMKKNLJM_00900 9.1e-44 yrhK S YrhK-like protein
KMKKNLJM_00901 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KMKKNLJM_00902 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KMKKNLJM_00903 1.1e-95 yrhH Q methyltransferase
KMKKNLJM_00905 2.6e-140 focA P Formate nitrite
KMKKNLJM_00906 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KMKKNLJM_00907 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KMKKNLJM_00908 5.4e-78 yrhD S Protein of unknown function (DUF1641)
KMKKNLJM_00909 4.6e-35 yrhC S YrhC-like protein
KMKKNLJM_00910 5.9e-208 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMKKNLJM_00911 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KMKKNLJM_00912 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KMKKNLJM_00913 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KMKKNLJM_00914 1e-25 yrzA S Protein of unknown function (DUF2536)
KMKKNLJM_00915 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KMKKNLJM_00916 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KMKKNLJM_00917 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KMKKNLJM_00918 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KMKKNLJM_00919 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KMKKNLJM_00920 4.3e-172 yegQ O Peptidase U32
KMKKNLJM_00921 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
KMKKNLJM_00922 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KMKKNLJM_00923 1.2e-45 yrzB S Belongs to the UPF0473 family
KMKKNLJM_00924 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KMKKNLJM_00925 1.7e-41 yrzL S Belongs to the UPF0297 family
KMKKNLJM_00926 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KMKKNLJM_00927 2.7e-170 yrrI S AI-2E family transporter
KMKKNLJM_00928 3.2e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMKKNLJM_00929 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KMKKNLJM_00930 1.8e-108 gluC P ABC transporter
KMKKNLJM_00931 7.6e-107 glnP P ABC transporter
KMKKNLJM_00932 8e-08 S Protein of unknown function (DUF3918)
KMKKNLJM_00933 9.8e-31 yrzR
KMKKNLJM_00934 3.9e-81 yrrD S protein conserved in bacteria
KMKKNLJM_00935 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KMKKNLJM_00936 1.4e-15 S COG0457 FOG TPR repeat
KMKKNLJM_00937 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KMKKNLJM_00938 2.6e-211 iscS 2.8.1.7 E Cysteine desulfurase
KMKKNLJM_00939 1.2e-70 cymR K Transcriptional regulator
KMKKNLJM_00940 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KMKKNLJM_00941 1.5e-135 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KMKKNLJM_00942 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KMKKNLJM_00943 1.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
KMKKNLJM_00945 2.2e-261 lytH 3.5.1.28 M COG3103 SH3 domain protein
KMKKNLJM_00946 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KMKKNLJM_00947 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KMKKNLJM_00948 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KMKKNLJM_00949 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KMKKNLJM_00950 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KMKKNLJM_00951 1.9e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KMKKNLJM_00952 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KMKKNLJM_00953 1.6e-48 yrzD S Post-transcriptional regulator
KMKKNLJM_00954 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_00955 9.2e-113 yrbG S membrane
KMKKNLJM_00956 1.2e-74 yrzE S Protein of unknown function (DUF3792)
KMKKNLJM_00957 8e-39 yajC U Preprotein translocase subunit YajC
KMKKNLJM_00958 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KMKKNLJM_00959 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KMKKNLJM_00960 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KMKKNLJM_00961 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KMKKNLJM_00962 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KMKKNLJM_00963 4.8e-93 bofC S BofC C-terminal domain
KMKKNLJM_00964 1.7e-251 csbX EGP Major facilitator Superfamily
KMKKNLJM_00965 1.1e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KMKKNLJM_00966 7.2e-118 yrzF T serine threonine protein kinase
KMKKNLJM_00968 3.1e-51 S Family of unknown function (DUF5412)
KMKKNLJM_00969 2.2e-260 alsT E Sodium alanine symporter
KMKKNLJM_00970 3.6e-126 yebC K transcriptional regulatory protein
KMKKNLJM_00971 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMKKNLJM_00972 4.8e-157 safA M spore coat assembly protein SafA
KMKKNLJM_00973 5.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KMKKNLJM_00974 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KMKKNLJM_00975 4.1e-300 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KMKKNLJM_00976 1.8e-228 nifS 2.8.1.7 E Cysteine desulfurase
KMKKNLJM_00977 3.9e-93 niaR S small molecule binding protein (contains 3H domain)
KMKKNLJM_00978 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
KMKKNLJM_00979 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KMKKNLJM_00980 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KMKKNLJM_00981 4.3e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KMKKNLJM_00982 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KMKKNLJM_00983 1.2e-55 ysxB J ribosomal protein
KMKKNLJM_00984 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KMKKNLJM_00985 5.9e-160 spoIVFB S Stage IV sporulation protein
KMKKNLJM_00986 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KMKKNLJM_00987 2.5e-144 minD D Belongs to the ParA family
KMKKNLJM_00988 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KMKKNLJM_00989 1.4e-84 mreD M shape-determining protein
KMKKNLJM_00990 1.1e-156 mreC M Involved in formation and maintenance of cell shape
KMKKNLJM_00991 1.8e-184 mreB D Rod shape-determining protein MreB
KMKKNLJM_00992 5.9e-126 radC E Belongs to the UPF0758 family
KMKKNLJM_00993 8.3e-102 maf D septum formation protein Maf
KMKKNLJM_00994 7.3e-162 spoIIB S Sporulation related domain
KMKKNLJM_00995 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KMKKNLJM_00996 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KMKKNLJM_00997 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KMKKNLJM_00998 1.6e-25
KMKKNLJM_00999 2.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KMKKNLJM_01000 6.2e-201 spoVID M stage VI sporulation protein D
KMKKNLJM_01001 5.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KMKKNLJM_01002 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
KMKKNLJM_01003 8.4e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KMKKNLJM_01004 3.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KMKKNLJM_01005 3.6e-146 hemX O cytochrome C
KMKKNLJM_01006 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KMKKNLJM_01007 1.4e-89 ysxD
KMKKNLJM_01008 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KMKKNLJM_01009 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KMKKNLJM_01010 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KMKKNLJM_01011 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KMKKNLJM_01012 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KMKKNLJM_01013 8.6e-187 ysoA H Tetratricopeptide repeat
KMKKNLJM_01014 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMKKNLJM_01015 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KMKKNLJM_01016 1.3e-199 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KMKKNLJM_01017 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KMKKNLJM_01018 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KMKKNLJM_01019 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KMKKNLJM_01020 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KMKKNLJM_01022 8.2e-76 ysnE K acetyltransferase
KMKKNLJM_01023 1.5e-135 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KMKKNLJM_01024 2.1e-130 ysnF S protein conserved in bacteria
KMKKNLJM_01026 4.1e-92 ysnB S Phosphoesterase
KMKKNLJM_01027 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KMKKNLJM_01028 2.6e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KMKKNLJM_01029 2.9e-196 gerM S COG5401 Spore germination protein
KMKKNLJM_01030 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KMKKNLJM_01031 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KMKKNLJM_01032 3.3e-30 gerE K Transcriptional regulator
KMKKNLJM_01033 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KMKKNLJM_01034 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KMKKNLJM_01035 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KMKKNLJM_01036 2.4e-107 sdhC C succinate dehydrogenase
KMKKNLJM_01037 1.2e-79 yslB S Protein of unknown function (DUF2507)
KMKKNLJM_01038 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KMKKNLJM_01039 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KMKKNLJM_01040 2e-52 trxA O Belongs to the thioredoxin family
KMKKNLJM_01041 2.9e-300 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KMKKNLJM_01043 6.7e-176 etfA C Electron transfer flavoprotein
KMKKNLJM_01044 4.5e-135 etfB C Electron transfer flavoprotein
KMKKNLJM_01045 1.6e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KMKKNLJM_01046 4e-99 fadR K Transcriptional regulator
KMKKNLJM_01047 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMKKNLJM_01048 7.3e-68 yshE S membrane
KMKKNLJM_01049 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KMKKNLJM_01050 0.0 polX L COG1796 DNA polymerase IV (family X)
KMKKNLJM_01051 1.7e-85 cvpA S membrane protein, required for colicin V production
KMKKNLJM_01052 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KMKKNLJM_01053 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMKKNLJM_01054 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMKKNLJM_01055 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KMKKNLJM_01056 1.6e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMKKNLJM_01057 2.6e-32 sspI S Belongs to the SspI family
KMKKNLJM_01058 7.3e-203 ysfB KT regulator
KMKKNLJM_01059 3.1e-259 glcD 1.1.3.15 C Glycolate oxidase subunit
KMKKNLJM_01060 1.5e-255 glcF C Glycolate oxidase
KMKKNLJM_01061 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
KMKKNLJM_01062 0.0 cstA T Carbon starvation protein
KMKKNLJM_01063 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KMKKNLJM_01064 2.4e-142 araQ G transport system permease
KMKKNLJM_01065 1.4e-167 araP G carbohydrate transport
KMKKNLJM_01066 4.9e-251 araN G carbohydrate transport
KMKKNLJM_01067 5.4e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KMKKNLJM_01068 6.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KMKKNLJM_01069 5.5e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KMKKNLJM_01070 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KMKKNLJM_01071 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KMKKNLJM_01072 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KMKKNLJM_01073 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
KMKKNLJM_01074 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KMKKNLJM_01075 7.5e-45 ysdA S Membrane
KMKKNLJM_01076 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KMKKNLJM_01077 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KMKKNLJM_01078 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KMKKNLJM_01080 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KMKKNLJM_01081 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KMKKNLJM_01082 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KMKKNLJM_01083 0.0 lytS 2.7.13.3 T Histidine kinase
KMKKNLJM_01084 7.3e-149 ysaA S HAD-hyrolase-like
KMKKNLJM_01085 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMKKNLJM_01087 1.6e-157 ytxC S YtxC-like family
KMKKNLJM_01088 1.1e-107 ytxB S SNARE associated Golgi protein
KMKKNLJM_01089 1.1e-172 dnaI L Primosomal protein DnaI
KMKKNLJM_01090 3.8e-265 dnaB L Membrane attachment protein
KMKKNLJM_01091 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KMKKNLJM_01092 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KMKKNLJM_01093 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMKKNLJM_01094 9.9e-67 ytcD K Transcriptional regulator
KMKKNLJM_01095 2.4e-204 ytbD EGP Major facilitator Superfamily
KMKKNLJM_01096 8.9e-161 ytbE S reductase
KMKKNLJM_01097 1.1e-96 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KMKKNLJM_01098 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KMKKNLJM_01099 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KMKKNLJM_01100 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KMKKNLJM_01101 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KMKKNLJM_01102 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_01103 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KMKKNLJM_01104 4.1e-242 icd 1.1.1.42 C isocitrate
KMKKNLJM_01105 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KMKKNLJM_01106 4.7e-71 yeaL S membrane
KMKKNLJM_01107 3.4e-192 ytvI S sporulation integral membrane protein YtvI
KMKKNLJM_01108 1.1e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KMKKNLJM_01109 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KMKKNLJM_01110 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KMKKNLJM_01111 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KMKKNLJM_01112 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KMKKNLJM_01113 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KMKKNLJM_01114 0.0 dnaE 2.7.7.7 L DNA polymerase
KMKKNLJM_01115 3.2e-56 ytrH S Sporulation protein YtrH
KMKKNLJM_01116 8.2e-69 ytrI
KMKKNLJM_01117 9.2e-29
KMKKNLJM_01118 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KMKKNLJM_01119 2.4e-47 ytpI S YtpI-like protein
KMKKNLJM_01120 8e-241 ytoI K transcriptional regulator containing CBS domains
KMKKNLJM_01121 2.7e-155 ytnM S membrane transporter protein
KMKKNLJM_01122 8.7e-237 ytnL 3.5.1.47 E hydrolase activity
KMKKNLJM_01123 1.5e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KMKKNLJM_01124 4.9e-254 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_01125 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
KMKKNLJM_01126 4.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_01127 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMKKNLJM_01128 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
KMKKNLJM_01129 1.1e-122 tcyL P Binding-protein-dependent transport system inner membrane component
KMKKNLJM_01130 4.9e-148 tcyK M Bacterial periplasmic substrate-binding proteins
KMKKNLJM_01131 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
KMKKNLJM_01132 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
KMKKNLJM_01133 1.9e-172 ytlI K LysR substrate binding domain
KMKKNLJM_01134 1.7e-130 ytkL S Belongs to the UPF0173 family
KMKKNLJM_01135 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_01137 7.5e-266 argH 4.3.2.1 E argininosuccinate lyase
KMKKNLJM_01138 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KMKKNLJM_01139 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KMKKNLJM_01140 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KMKKNLJM_01141 7e-165 ytxK 2.1.1.72 L DNA methylase
KMKKNLJM_01142 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KMKKNLJM_01143 8.7e-70 ytfJ S Sporulation protein YtfJ
KMKKNLJM_01144 2.1e-115 ytfI S Protein of unknown function (DUF2953)
KMKKNLJM_01145 8.5e-87 yteJ S RDD family
KMKKNLJM_01146 7.4e-178 sppA OU signal peptide peptidase SppA
KMKKNLJM_01147 1.1e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMKKNLJM_01148 0.0 ytcJ S amidohydrolase
KMKKNLJM_01149 2.3e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMKKNLJM_01150 2e-29 sspB S spore protein
KMKKNLJM_01151 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KMKKNLJM_01152 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
KMKKNLJM_01153 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KMKKNLJM_01154 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KMKKNLJM_01155 3.5e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KMKKNLJM_01156 1e-108 yttP K Transcriptional regulator
KMKKNLJM_01157 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KMKKNLJM_01158 8.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KMKKNLJM_01159 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KMKKNLJM_01161 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMKKNLJM_01162 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KMKKNLJM_01163 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KMKKNLJM_01164 3.5e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KMKKNLJM_01165 6.1e-224 acuC BQ histone deacetylase
KMKKNLJM_01166 4e-125 motS N Flagellar motor protein
KMKKNLJM_01167 2.1e-146 motA N flagellar motor
KMKKNLJM_01168 3.8e-182 ccpA K catabolite control protein A
KMKKNLJM_01169 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KMKKNLJM_01170 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
KMKKNLJM_01171 6.6e-17 ytxH S COG4980 Gas vesicle protein
KMKKNLJM_01172 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KMKKNLJM_01173 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KMKKNLJM_01174 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KMKKNLJM_01175 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KMKKNLJM_01176 9.8e-149 ytpQ S Belongs to the UPF0354 family
KMKKNLJM_01177 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KMKKNLJM_01178 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KMKKNLJM_01179 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KMKKNLJM_01180 2.2e-51 ytzB S small secreted protein
KMKKNLJM_01181 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KMKKNLJM_01182 4.6e-149 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KMKKNLJM_01183 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KMKKNLJM_01184 2e-45 ytzH S YtzH-like protein
KMKKNLJM_01185 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KMKKNLJM_01186 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KMKKNLJM_01187 6.6e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KMKKNLJM_01188 2.9e-165 ytlQ
KMKKNLJM_01189 7.5e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KMKKNLJM_01190 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMKKNLJM_01191 1.5e-269 pepV 3.5.1.18 E Dipeptidase
KMKKNLJM_01192 7.2e-226 pbuO S permease
KMKKNLJM_01193 3.8e-202 ythQ U Bacterial ABC transporter protein EcsB
KMKKNLJM_01194 1.3e-131 ythP V ABC transporter
KMKKNLJM_01195 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KMKKNLJM_01196 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KMKKNLJM_01197 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_01198 2e-230 ytfP S HI0933-like protein
KMKKNLJM_01199 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KMKKNLJM_01200 3.1e-26 yteV S Sporulation protein Cse60
KMKKNLJM_01201 5.3e-116 yteU S Integral membrane protein
KMKKNLJM_01202 1.3e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KMKKNLJM_01203 6.2e-70 yteS G transport
KMKKNLJM_01204 5.2e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KMKKNLJM_01205 7.5e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KMKKNLJM_01206 0.0 ytdP K Transcriptional regulator
KMKKNLJM_01207 8.9e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KMKKNLJM_01208 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
KMKKNLJM_01209 3.1e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KMKKNLJM_01210 8.3e-221 bioI 1.14.14.46 C Cytochrome P450
KMKKNLJM_01211 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KMKKNLJM_01212 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KMKKNLJM_01213 4.5e-211 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMKKNLJM_01214 2.7e-260 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KMKKNLJM_01215 1.5e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KMKKNLJM_01216 1.1e-172 ytaP S Acetyl xylan esterase (AXE1)
KMKKNLJM_01217 5.6e-189 msmR K Transcriptional regulator
KMKKNLJM_01218 7.5e-244 msmE G Bacterial extracellular solute-binding protein
KMKKNLJM_01219 6.2e-168 amyD P ABC transporter
KMKKNLJM_01220 4.4e-144 amyC P ABC transporter (permease)
KMKKNLJM_01221 2.2e-251 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KMKKNLJM_01222 2.1e-51 ytwF P Sulfurtransferase
KMKKNLJM_01223 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMKKNLJM_01224 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KMKKNLJM_01225 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KMKKNLJM_01226 3.9e-210 yttB EGP Major facilitator Superfamily
KMKKNLJM_01227 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
KMKKNLJM_01228 0.0 bceB V ABC transporter (permease)
KMKKNLJM_01229 7.3e-138 bceA V ABC transporter, ATP-binding protein
KMKKNLJM_01230 1.2e-185 T PhoQ Sensor
KMKKNLJM_01231 1.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_01232 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KMKKNLJM_01233 9.1e-127 ytrE V ABC transporter, ATP-binding protein
KMKKNLJM_01234 2.6e-148
KMKKNLJM_01235 6.1e-153 P ABC-2 family transporter protein
KMKKNLJM_01236 2.1e-160 ytrB P abc transporter atp-binding protein
KMKKNLJM_01237 5.1e-66 ytrA K GntR family transcriptional regulator
KMKKNLJM_01239 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KMKKNLJM_01240 8.1e-190 yhcC S Fe-S oxidoreductase
KMKKNLJM_01241 9.7e-106 ytqB J Putative rRNA methylase
KMKKNLJM_01242 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KMKKNLJM_01243 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KMKKNLJM_01244 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KMKKNLJM_01245 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_01246 0.0 asnB 6.3.5.4 E Asparagine synthase
KMKKNLJM_01247 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KMKKNLJM_01248 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KMKKNLJM_01249 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KMKKNLJM_01250 5.2e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KMKKNLJM_01251 8e-188 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KMKKNLJM_01252 1.4e-144 ytlC P ABC transporter
KMKKNLJM_01253 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMKKNLJM_01254 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KMKKNLJM_01255 7.8e-62 ytkC S Bacteriophage holin family
KMKKNLJM_01256 2.1e-76 dps P Belongs to the Dps family
KMKKNLJM_01258 2.4e-72 ytkA S YtkA-like
KMKKNLJM_01259 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KMKKNLJM_01260 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KMKKNLJM_01261 6.1e-41 rpmE2 J Ribosomal protein L31
KMKKNLJM_01262 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
KMKKNLJM_01263 2.8e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KMKKNLJM_01264 1.1e-24 S Domain of Unknown Function (DUF1540)
KMKKNLJM_01265 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KMKKNLJM_01266 4.4e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMKKNLJM_01267 6.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMKKNLJM_01268 3.9e-170 troA P Belongs to the bacterial solute-binding protein 9 family
KMKKNLJM_01269 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KMKKNLJM_01270 6.7e-273 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KMKKNLJM_01271 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KMKKNLJM_01272 1.4e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KMKKNLJM_01273 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KMKKNLJM_01274 1.6e-271 menF 5.4.4.2 HQ Isochorismate synthase
KMKKNLJM_01275 2.6e-132 dksA T COG1734 DnaK suppressor protein
KMKKNLJM_01276 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
KMKKNLJM_01277 3.7e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMKKNLJM_01278 6.9e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KMKKNLJM_01279 1e-234 ytcC M Glycosyltransferase Family 4
KMKKNLJM_01281 2.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
KMKKNLJM_01282 1.8e-217 cotSA M Glycosyl transferases group 1
KMKKNLJM_01283 3.7e-204 cotI S Spore coat protein
KMKKNLJM_01284 4.9e-76 tspO T membrane
KMKKNLJM_01285 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KMKKNLJM_01286 7.6e-285 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KMKKNLJM_01287 4.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KMKKNLJM_01288 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KMKKNLJM_01289 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KMKKNLJM_01298 7.8e-08
KMKKNLJM_01299 1.3e-09
KMKKNLJM_01306 2e-08
KMKKNLJM_01311 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01312 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01313 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01314 1.6e-249 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01315 4e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01316 3.4e-39 S COG NOG14552 non supervised orthologous group
KMKKNLJM_01317 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KMKKNLJM_01318 5.5e-92 M1-753 M FR47-like protein
KMKKNLJM_01319 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KMKKNLJM_01320 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KMKKNLJM_01321 3.9e-84 yuaE S DinB superfamily
KMKKNLJM_01322 1.1e-106 yuaD
KMKKNLJM_01323 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KMKKNLJM_01324 5.2e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KMKKNLJM_01325 5.5e-95 yuaC K Belongs to the GbsR family
KMKKNLJM_01326 2.2e-91 yuaB
KMKKNLJM_01327 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KMKKNLJM_01328 6e-236 ktrB P Potassium
KMKKNLJM_01329 1e-38 yiaA S yiaA/B two helix domain
KMKKNLJM_01330 3.2e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMKKNLJM_01331 4.9e-274 yubD P Major Facilitator Superfamily
KMKKNLJM_01332 3.2e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KMKKNLJM_01334 5.9e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KMKKNLJM_01335 3.7e-189 yubA S transporter activity
KMKKNLJM_01336 3.7e-182 ygjR S Oxidoreductase
KMKKNLJM_01337 1.3e-248 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KMKKNLJM_01338 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KMKKNLJM_01339 3.3e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KMKKNLJM_01340 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KMKKNLJM_01341 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KMKKNLJM_01342 7.3e-238 mcpA NT chemotaxis protein
KMKKNLJM_01343 5.2e-292 mcpA NT chemotaxis protein
KMKKNLJM_01344 2.8e-221 mcpA NT chemotaxis protein
KMKKNLJM_01345 3.5e-224 mcpA NT chemotaxis protein
KMKKNLJM_01346 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KMKKNLJM_01347 1e-35
KMKKNLJM_01348 4.1e-71 yugU S Uncharacterised protein family UPF0047
KMKKNLJM_01349 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KMKKNLJM_01350 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KMKKNLJM_01351 1.4e-116 yugP S Zn-dependent protease
KMKKNLJM_01352 2.3e-38
KMKKNLJM_01353 3.2e-53 mstX S Membrane-integrating protein Mistic
KMKKNLJM_01354 2.2e-182 yugO P COG1226 Kef-type K transport systems
KMKKNLJM_01355 1.7e-72 yugN S YugN-like family
KMKKNLJM_01357 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KMKKNLJM_01358 1.2e-227 yugK C Dehydrogenase
KMKKNLJM_01359 6.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KMKKNLJM_01360 4e-34 yuzA S Domain of unknown function (DUF378)
KMKKNLJM_01361 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KMKKNLJM_01362 2.1e-199 yugH 2.6.1.1 E Aminotransferase
KMKKNLJM_01363 1.6e-85 alaR K Transcriptional regulator
KMKKNLJM_01364 3.2e-155 yugF I Hydrolase
KMKKNLJM_01365 4.6e-39 yugE S Domain of unknown function (DUF1871)
KMKKNLJM_01366 4.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KMKKNLJM_01367 4.6e-233 T PhoQ Sensor
KMKKNLJM_01368 6.3e-69 kapB G Kinase associated protein B
KMKKNLJM_01369 4.2e-115 kapD L the KinA pathway to sporulation
KMKKNLJM_01371 2.1e-183 yuxJ EGP Major facilitator Superfamily
KMKKNLJM_01372 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KMKKNLJM_01373 6.3e-75 yuxK S protein conserved in bacteria
KMKKNLJM_01374 6.3e-78 yufK S Family of unknown function (DUF5366)
KMKKNLJM_01375 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMKKNLJM_01376 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KMKKNLJM_01377 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KMKKNLJM_01378 1e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KMKKNLJM_01379 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KMKKNLJM_01380 7.8e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
KMKKNLJM_01381 2.4e-232 maeN C COG3493 Na citrate symporter
KMKKNLJM_01382 5e-15
KMKKNLJM_01383 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KMKKNLJM_01384 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMKKNLJM_01385 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMKKNLJM_01386 2.1e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMKKNLJM_01387 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMKKNLJM_01388 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KMKKNLJM_01389 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KMKKNLJM_01390 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KMKKNLJM_01391 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_01392 3.2e-269 comP 2.7.13.3 T Histidine kinase
KMKKNLJM_01394 3.6e-142 comQ H Belongs to the FPP GGPP synthase family
KMKKNLJM_01396 8.5e-23 yuzC
KMKKNLJM_01397 2e-230 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KMKKNLJM_01398 1.4e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KMKKNLJM_01399 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
KMKKNLJM_01400 7.9e-67 yueI S Protein of unknown function (DUF1694)
KMKKNLJM_01401 2.8e-38 yueH S YueH-like protein
KMKKNLJM_01402 6.6e-31 yueG S Spore germination protein gerPA/gerPF
KMKKNLJM_01403 3.2e-190 yueF S transporter activity
KMKKNLJM_01404 2.9e-24 S Protein of unknown function (DUF2642)
KMKKNLJM_01405 4.8e-96 yueE S phosphohydrolase
KMKKNLJM_01406 1.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_01407 3.3e-64 yueC S Family of unknown function (DUF5383)
KMKKNLJM_01408 0.0 esaA S type VII secretion protein EsaA
KMKKNLJM_01409 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KMKKNLJM_01410 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KMKKNLJM_01411 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KMKKNLJM_01412 2.8e-45 esxA S Belongs to the WXG100 family
KMKKNLJM_01413 7.2e-228 yukF QT Transcriptional regulator
KMKKNLJM_01414 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KMKKNLJM_01415 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KMKKNLJM_01416 5e-36 mbtH S MbtH-like protein
KMKKNLJM_01417 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_01418 9.3e-175 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KMKKNLJM_01419 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KMKKNLJM_01420 2.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
KMKKNLJM_01421 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_01422 3.9e-167 besA S Putative esterase
KMKKNLJM_01423 6.4e-121 yuiH S Oxidoreductase molybdopterin binding domain
KMKKNLJM_01424 5.7e-93 bioY S Biotin biosynthesis protein
KMKKNLJM_01425 3.9e-211 yuiF S antiporter
KMKKNLJM_01426 5.8e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KMKKNLJM_01427 1.2e-77 yuiD S protein conserved in bacteria
KMKKNLJM_01428 2.1e-117 yuiC S protein conserved in bacteria
KMKKNLJM_01429 8.4e-27 yuiB S Putative membrane protein
KMKKNLJM_01430 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
KMKKNLJM_01431 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
KMKKNLJM_01433 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KMKKNLJM_01434 4.2e-115 paiB K Putative FMN-binding domain
KMKKNLJM_01435 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_01436 3.7e-63 erpA S Belongs to the HesB IscA family
KMKKNLJM_01437 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KMKKNLJM_01438 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMKKNLJM_01439 3.2e-39 yuzB S Belongs to the UPF0349 family
KMKKNLJM_01440 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KMKKNLJM_01441 1.1e-55 yuzD S protein conserved in bacteria
KMKKNLJM_01442 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KMKKNLJM_01443 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KMKKNLJM_01444 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KMKKNLJM_01445 3.4e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KMKKNLJM_01446 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
KMKKNLJM_01447 1e-198 yutH S Spore coat protein
KMKKNLJM_01448 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KMKKNLJM_01449 2.5e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KMKKNLJM_01450 8.6e-75 yutE S Protein of unknown function DUF86
KMKKNLJM_01451 9.7e-48 yutD S protein conserved in bacteria
KMKKNLJM_01452 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMKKNLJM_01453 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KMKKNLJM_01454 8.4e-195 lytH M Peptidase, M23
KMKKNLJM_01455 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
KMKKNLJM_01456 5.3e-47 yunC S Domain of unknown function (DUF1805)
KMKKNLJM_01457 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KMKKNLJM_01458 7.2e-139 yunE S membrane transporter protein
KMKKNLJM_01459 4.3e-171 yunF S Protein of unknown function DUF72
KMKKNLJM_01460 3.1e-59 yunG
KMKKNLJM_01461 4.7e-257 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KMKKNLJM_01462 2.4e-300 pucR QT COG2508 Regulator of polyketide synthase expression
KMKKNLJM_01463 5.5e-229 pbuX F Permease family
KMKKNLJM_01464 1.9e-223 pbuX F xanthine
KMKKNLJM_01465 6e-277 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KMKKNLJM_01466 3.2e-56 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KMKKNLJM_01468 2.8e-96 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KMKKNLJM_01469 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KMKKNLJM_01470 1.2e-144 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KMKKNLJM_01471 1.7e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KMKKNLJM_01472 8.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KMKKNLJM_01473 1e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KMKKNLJM_01474 7.5e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KMKKNLJM_01475 2.4e-169 bsn L Ribonuclease
KMKKNLJM_01476 1.7e-204 msmX P Belongs to the ABC transporter superfamily
KMKKNLJM_01477 2.1e-134 yurK K UTRA
KMKKNLJM_01478 2.2e-162 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KMKKNLJM_01479 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
KMKKNLJM_01480 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
KMKKNLJM_01481 4.7e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KMKKNLJM_01482 1.3e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KMKKNLJM_01483 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KMKKNLJM_01484 8.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KMKKNLJM_01486 1e-41
KMKKNLJM_01487 2.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_01488 3.5e-271 sufB O FeS cluster assembly
KMKKNLJM_01489 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KMKKNLJM_01490 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KMKKNLJM_01491 1.4e-245 sufD O assembly protein SufD
KMKKNLJM_01492 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KMKKNLJM_01493 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMKKNLJM_01494 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
KMKKNLJM_01495 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KMKKNLJM_01496 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KMKKNLJM_01497 2.4e-56 yusD S SCP-2 sterol transfer family
KMKKNLJM_01498 5.6e-55 traF CO Thioredoxin
KMKKNLJM_01499 1.6e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KMKKNLJM_01500 4.1e-39 yusG S Protein of unknown function (DUF2553)
KMKKNLJM_01501 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KMKKNLJM_01502 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KMKKNLJM_01503 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KMKKNLJM_01504 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
KMKKNLJM_01505 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KMKKNLJM_01506 8.1e-09 S YuzL-like protein
KMKKNLJM_01507 8.4e-165 fadM E Proline dehydrogenase
KMKKNLJM_01508 5.1e-40
KMKKNLJM_01509 5.4e-53 yusN M Coat F domain
KMKKNLJM_01510 2.6e-66 yusO K Iron dependent repressor, N-terminal DNA binding domain
KMKKNLJM_01511 8.5e-293 yusP P Major facilitator superfamily
KMKKNLJM_01512 7.1e-65 yusQ S Tautomerase enzyme
KMKKNLJM_01513 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_01514 7.4e-158 yusT K LysR substrate binding domain
KMKKNLJM_01515 2.1e-38 yusU S Protein of unknown function (DUF2573)
KMKKNLJM_01516 5.1e-153 yusV 3.6.3.34 HP ABC transporter
KMKKNLJM_01517 1.9e-66 S YusW-like protein
KMKKNLJM_01518 3.3e-298 pepF2 E COG1164 Oligoendopeptidase F
KMKKNLJM_01519 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_01520 2.7e-79 dps P Ferritin-like domain
KMKKNLJM_01521 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMKKNLJM_01522 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_01523 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KMKKNLJM_01524 3.6e-157 yuxN K Transcriptional regulator
KMKKNLJM_01525 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KMKKNLJM_01526 2.3e-24 S Protein of unknown function (DUF3970)
KMKKNLJM_01527 3.1e-246 gerAA EG Spore germination protein
KMKKNLJM_01528 1.5e-195 gerAB E Spore germination protein
KMKKNLJM_01529 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
KMKKNLJM_01530 6.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_01531 7.9e-186 vraS 2.7.13.3 T Histidine kinase
KMKKNLJM_01532 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KMKKNLJM_01533 1.8e-119 liaG S Putative adhesin
KMKKNLJM_01534 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KMKKNLJM_01535 8.1e-61 liaI S membrane
KMKKNLJM_01536 4.8e-227 yvqJ EGP Major facilitator Superfamily
KMKKNLJM_01537 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
KMKKNLJM_01538 1.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KMKKNLJM_01539 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_01540 1e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KMKKNLJM_01541 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_01542 2.2e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
KMKKNLJM_01543 0.0 T PhoQ Sensor
KMKKNLJM_01544 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_01545 7.2e-23
KMKKNLJM_01546 9.5e-98 yvrI K RNA polymerase
KMKKNLJM_01547 2.4e-19 S YvrJ protein family
KMKKNLJM_01548 8.1e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
KMKKNLJM_01549 3.8e-64 yvrL S Regulatory protein YrvL
KMKKNLJM_01550 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KMKKNLJM_01551 2.1e-123 macB V ABC transporter, ATP-binding protein
KMKKNLJM_01552 2e-174 M Efflux transporter rnd family, mfp subunit
KMKKNLJM_01553 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KMKKNLJM_01554 6.9e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_01555 3.3e-156 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_01556 8.5e-176 fhuD P ABC transporter
KMKKNLJM_01557 4.1e-235 yvsH E Arginine ornithine antiporter
KMKKNLJM_01558 6.5e-16 S Small spore protein J (Spore_SspJ)
KMKKNLJM_01559 3.9e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KMKKNLJM_01560 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMKKNLJM_01561 1.6e-166 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KMKKNLJM_01562 7.8e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KMKKNLJM_01563 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KMKKNLJM_01564 1.7e-156 yvgN S reductase
KMKKNLJM_01565 2.1e-85 yvgO
KMKKNLJM_01566 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KMKKNLJM_01567 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KMKKNLJM_01568 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KMKKNLJM_01569 0.0 helD 3.6.4.12 L DNA helicase
KMKKNLJM_01571 1.6e-106 yvgT S membrane
KMKKNLJM_01572 7.2e-71 bdbC O Required for disulfide bond formation in some proteins
KMKKNLJM_01573 1.4e-103 bdbD O Thioredoxin
KMKKNLJM_01574 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KMKKNLJM_01575 0.0 copA 3.6.3.54 P P-type ATPase
KMKKNLJM_01576 1.5e-29 copZ P Copper resistance protein CopZ
KMKKNLJM_01577 6.3e-48 csoR S transcriptional
KMKKNLJM_01578 1.9e-192 yvaA 1.1.1.371 S Oxidoreductase
KMKKNLJM_01579 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KMKKNLJM_01580 0.0 yvaC S Fusaric acid resistance protein-like
KMKKNLJM_01581 1.3e-72 yvaD S Family of unknown function (DUF5360)
KMKKNLJM_01582 2.4e-54 yvaE P Small Multidrug Resistance protein
KMKKNLJM_01583 1e-96 K Bacterial regulatory proteins, tetR family
KMKKNLJM_01584 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_01586 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KMKKNLJM_01587 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KMKKNLJM_01588 5.6e-143 est 3.1.1.1 S Carboxylesterase
KMKKNLJM_01589 2.4e-23 secG U Preprotein translocase subunit SecG
KMKKNLJM_01590 8.2e-153 yvaM S Serine aminopeptidase, S33
KMKKNLJM_01591 9.8e-36 yvzC K Transcriptional
KMKKNLJM_01592 4e-69 K transcriptional
KMKKNLJM_01593 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
KMKKNLJM_01594 1.4e-53 yodB K transcriptional
KMKKNLJM_01596 6.2e-22 S Protein of unknown function (DUF2283)
KMKKNLJM_01597 1.9e-15 M COG3209 Rhs family protein
KMKKNLJM_01598 2e-42 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KMKKNLJM_01599 1.8e-100 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMKKNLJM_01600 2.3e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMKKNLJM_01601 3.1e-108 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMKKNLJM_01602 8.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMKKNLJM_01603 7.4e-60 yvbF K Belongs to the GbsR family
KMKKNLJM_01604 1.1e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMKKNLJM_01605 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KMKKNLJM_01606 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KMKKNLJM_01607 3.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KMKKNLJM_01608 3.5e-97 yvbF K Belongs to the GbsR family
KMKKNLJM_01609 3.5e-101 yvbG U UPF0056 membrane protein
KMKKNLJM_01610 8.6e-113 yvbH S YvbH-like oligomerisation region
KMKKNLJM_01611 4e-122 exoY M Membrane
KMKKNLJM_01612 0.0 tcaA S response to antibiotic
KMKKNLJM_01613 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
KMKKNLJM_01614 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KMKKNLJM_01615 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KMKKNLJM_01616 5.6e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KMKKNLJM_01617 3.8e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KMKKNLJM_01618 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KMKKNLJM_01619 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMKKNLJM_01620 1.6e-252 araE EGP Major facilitator Superfamily
KMKKNLJM_01621 1.6e-202 araR K transcriptional
KMKKNLJM_01622 9.9e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_01623 3.9e-159 yvbU K Transcriptional regulator
KMKKNLJM_01624 2.1e-155 yvbV EG EamA-like transporter family
KMKKNLJM_01625 4.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_01626 2.8e-196 yvbX S Glycosyl hydrolase
KMKKNLJM_01627 5.7e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMKKNLJM_01628 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KMKKNLJM_01629 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KMKKNLJM_01630 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_01631 2.1e-197 desK 2.7.13.3 T Histidine kinase
KMKKNLJM_01632 3.4e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
KMKKNLJM_01633 1.4e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KMKKNLJM_01634 3.7e-156 rsbQ S Alpha/beta hydrolase family
KMKKNLJM_01635 3.2e-196 rsbU 3.1.3.3 T response regulator
KMKKNLJM_01636 6.4e-251 galA 3.2.1.89 G arabinogalactan
KMKKNLJM_01637 0.0 lacA 3.2.1.23 G beta-galactosidase
KMKKNLJM_01638 7.2e-150 ganQ P transport
KMKKNLJM_01639 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
KMKKNLJM_01640 2.3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
KMKKNLJM_01641 3e-184 lacR K Transcriptional regulator
KMKKNLJM_01642 1e-112 yvfI K COG2186 Transcriptional regulators
KMKKNLJM_01643 2.2e-307 yvfH C L-lactate permease
KMKKNLJM_01644 5.2e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KMKKNLJM_01645 1.7e-31 yvfG S YvfG protein
KMKKNLJM_01646 7.5e-188 yvfF GM Exopolysaccharide biosynthesis protein
KMKKNLJM_01647 2.9e-218 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KMKKNLJM_01648 2.4e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KMKKNLJM_01649 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMKKNLJM_01650 1.7e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_01651 7e-192 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KMKKNLJM_01652 3.7e-204 epsI GM pyruvyl transferase
KMKKNLJM_01653 9.8e-194 epsH GT2 S Glycosyltransferase like family 2
KMKKNLJM_01654 1.1e-206 epsG S EpsG family
KMKKNLJM_01655 1.1e-217 epsF GT4 M Glycosyl transferases group 1
KMKKNLJM_01656 2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMKKNLJM_01657 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
KMKKNLJM_01658 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KMKKNLJM_01659 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KMKKNLJM_01660 8.9e-122 ywqC M biosynthesis protein
KMKKNLJM_01661 6.3e-76 slr K transcriptional
KMKKNLJM_01662 2.1e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KMKKNLJM_01664 4.6e-93 padC Q Phenolic acid decarboxylase
KMKKNLJM_01665 9.3e-72 MA20_18690 S Protein of unknown function (DUF3237)
KMKKNLJM_01666 4.9e-125 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KMKKNLJM_01667 4.5e-263 pbpE V Beta-lactamase
KMKKNLJM_01668 9.3e-66
KMKKNLJM_01669 5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
KMKKNLJM_01670 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KMKKNLJM_01671 5.1e-295 yveA E amino acid
KMKKNLJM_01672 2.6e-106 yvdT K Transcriptional regulator
KMKKNLJM_01673 1.5e-50 ykkC P Small Multidrug Resistance protein
KMKKNLJM_01674 7.1e-50 sugE P Small Multidrug Resistance protein
KMKKNLJM_01675 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
KMKKNLJM_01676 2.3e-173 S Patatin-like phospholipase
KMKKNLJM_01678 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KMKKNLJM_01679 3.5e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KMKKNLJM_01680 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KMKKNLJM_01681 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KMKKNLJM_01682 1.1e-153 malA S Protein of unknown function (DUF1189)
KMKKNLJM_01683 3.9e-148 malD P transport
KMKKNLJM_01684 2e-244 malC P COG1175 ABC-type sugar transport systems, permease components
KMKKNLJM_01685 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KMKKNLJM_01686 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KMKKNLJM_01687 1e-173 yvdE K Transcriptional regulator
KMKKNLJM_01688 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KMKKNLJM_01689 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
KMKKNLJM_01690 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KMKKNLJM_01691 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KMKKNLJM_01692 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KMKKNLJM_01693 0.0 yxdM V ABC transporter (permease)
KMKKNLJM_01694 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KMKKNLJM_01695 6.8e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KMKKNLJM_01696 1.9e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_01697 8.8e-33
KMKKNLJM_01698 4.3e-146 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KMKKNLJM_01699 1.6e-36 crh G Phosphocarrier protein Chr
KMKKNLJM_01700 1.4e-170 whiA K May be required for sporulation
KMKKNLJM_01701 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KMKKNLJM_01702 5.7e-166 rapZ S Displays ATPase and GTPase activities
KMKKNLJM_01703 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KMKKNLJM_01704 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KMKKNLJM_01705 4.3e-99 usp CBM50 M protein conserved in bacteria
KMKKNLJM_01706 6.5e-276 S COG0457 FOG TPR repeat
KMKKNLJM_01707 0.0 msbA2 3.6.3.44 V ABC transporter
KMKKNLJM_01709 5.5e-251
KMKKNLJM_01710 3.7e-78
KMKKNLJM_01711 1.8e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KMKKNLJM_01712 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KMKKNLJM_01713 1.3e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KMKKNLJM_01714 6.2e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KMKKNLJM_01715 2e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KMKKNLJM_01716 1.5e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KMKKNLJM_01717 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KMKKNLJM_01718 1.8e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KMKKNLJM_01719 4.5e-140 yvpB NU protein conserved in bacteria
KMKKNLJM_01720 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KMKKNLJM_01721 8.7e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KMKKNLJM_01722 1.9e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KMKKNLJM_01723 1.1e-159 yvoD P COG0370 Fe2 transport system protein B
KMKKNLJM_01724 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KMKKNLJM_01725 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KMKKNLJM_01726 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KMKKNLJM_01727 3.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMKKNLJM_01728 2e-132 yvoA K transcriptional
KMKKNLJM_01729 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KMKKNLJM_01730 1.2e-50 yvlD S Membrane
KMKKNLJM_01731 2.6e-26 pspB KT PspC domain
KMKKNLJM_01732 9.2e-166 yvlB S Putative adhesin
KMKKNLJM_01733 8e-49 yvlA
KMKKNLJM_01734 5.7e-33 yvkN
KMKKNLJM_01735 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMKKNLJM_01736 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KMKKNLJM_01737 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KMKKNLJM_01738 1.2e-30 csbA S protein conserved in bacteria
KMKKNLJM_01739 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KMKKNLJM_01740 1e-99 yvkB K Transcriptional regulator
KMKKNLJM_01741 2.8e-225 yvkA EGP Major facilitator Superfamily
KMKKNLJM_01742 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMKKNLJM_01743 5.3e-56 swrA S Swarming motility protein
KMKKNLJM_01744 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KMKKNLJM_01745 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KMKKNLJM_01746 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KMKKNLJM_01747 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KMKKNLJM_01748 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KMKKNLJM_01749 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KMKKNLJM_01750 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KMKKNLJM_01751 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KMKKNLJM_01752 1.1e-49
KMKKNLJM_01753 1.9e-08 fliT S bacterial-type flagellum organization
KMKKNLJM_01754 2.9e-69 fliS N flagellar protein FliS
KMKKNLJM_01755 1.5e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KMKKNLJM_01756 1.2e-52 flaG N flagellar protein FlaG
KMKKNLJM_01757 5.9e-93 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KMKKNLJM_01758 1.3e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KMKKNLJM_01759 1.2e-71 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KMKKNLJM_01760 4.8e-49 yviE
KMKKNLJM_01761 7.8e-155 flgL N Belongs to the bacterial flagellin family
KMKKNLJM_01762 5e-263 flgK N flagellar hook-associated protein
KMKKNLJM_01763 2.7e-77 flgN NOU FlgN protein
KMKKNLJM_01764 2.3e-38 flgM KNU Negative regulator of flagellin synthesis
KMKKNLJM_01765 2e-73 yvyF S flagellar protein
KMKKNLJM_01766 3.6e-126 comFC S Phosphoribosyl transferase domain
KMKKNLJM_01767 3.7e-45 comFB S Late competence development protein ComFB
KMKKNLJM_01768 9e-267 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KMKKNLJM_01769 2.1e-154 degV S protein conserved in bacteria
KMKKNLJM_01770 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_01771 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KMKKNLJM_01772 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KMKKNLJM_01773 6e-163 yvhJ K Transcriptional regulator
KMKKNLJM_01774 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KMKKNLJM_01775 6.2e-232 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KMKKNLJM_01776 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KMKKNLJM_01777 5.1e-114 tuaF M protein involved in exopolysaccharide biosynthesis
KMKKNLJM_01778 8.3e-263 tuaE M Teichuronic acid biosynthesis protein
KMKKNLJM_01779 6.4e-257 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMKKNLJM_01780 4e-220 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KMKKNLJM_01781 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_01782 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KMKKNLJM_01783 1.5e-94 M Glycosyltransferase like family 2
KMKKNLJM_01784 3.5e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMKKNLJM_01785 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KMKKNLJM_01786 1e-11
KMKKNLJM_01787 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KMKKNLJM_01788 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KMKKNLJM_01789 2.7e-88 M Glycosyltransferase like family 2
KMKKNLJM_01790 5.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KMKKNLJM_01791 8.3e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KMKKNLJM_01792 4.5e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KMKKNLJM_01793 1.7e-274 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KMKKNLJM_01794 1e-132 tagG GM Transport permease protein
KMKKNLJM_01795 5.2e-90
KMKKNLJM_01796 1.2e-55
KMKKNLJM_01797 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KMKKNLJM_01798 2.9e-89 ggaA M Glycosyltransferase like family 2
KMKKNLJM_01799 2.5e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMKKNLJM_01800 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KMKKNLJM_01801 7.8e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KMKKNLJM_01802 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KMKKNLJM_01803 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KMKKNLJM_01804 4e-147 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KMKKNLJM_01805 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KMKKNLJM_01806 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KMKKNLJM_01807 2.6e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KMKKNLJM_01808 2.3e-189 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KMKKNLJM_01809 1.3e-263 gerBA EG Spore germination protein
KMKKNLJM_01810 8.1e-194 gerBB E Spore germination protein
KMKKNLJM_01811 2.2e-207 gerAC S Spore germination protein
KMKKNLJM_01812 2.7e-247 ywtG EGP Major facilitator Superfamily
KMKKNLJM_01813 1.6e-169 ywtF K Transcriptional regulator
KMKKNLJM_01814 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KMKKNLJM_01815 1.2e-239 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMKKNLJM_01816 3.6e-21 ywtC
KMKKNLJM_01817 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KMKKNLJM_01818 8.6e-70 pgsC S biosynthesis protein
KMKKNLJM_01819 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KMKKNLJM_01820 5.5e-178 rbsR K transcriptional
KMKKNLJM_01821 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KMKKNLJM_01822 5.8e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KMKKNLJM_01823 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KMKKNLJM_01824 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KMKKNLJM_01825 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KMKKNLJM_01826 9.6e-92 batE T Sh3 type 3 domain protein
KMKKNLJM_01827 8e-48 ywsA S Protein of unknown function (DUF3892)
KMKKNLJM_01828 1.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KMKKNLJM_01829 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KMKKNLJM_01830 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KMKKNLJM_01831 1.1e-169 alsR K LysR substrate binding domain
KMKKNLJM_01832 1.4e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMKKNLJM_01833 5.4e-124 ywrJ
KMKKNLJM_01834 1.8e-122 cotB
KMKKNLJM_01835 1.8e-206 cotH M Spore Coat
KMKKNLJM_01836 1.3e-12
KMKKNLJM_01837 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KMKKNLJM_01838 5e-54 S Domain of unknown function (DUF4181)
KMKKNLJM_01839 2.2e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KMKKNLJM_01840 8e-82 ywrC K Transcriptional regulator
KMKKNLJM_01841 7.1e-104 ywrB P Chromate transporter
KMKKNLJM_01842 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
KMKKNLJM_01844 3.5e-97 ywqN S NAD(P)H-dependent
KMKKNLJM_01845 9.3e-161 K Transcriptional regulator
KMKKNLJM_01846 7.2e-127 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KMKKNLJM_01847 9.8e-99
KMKKNLJM_01849 8.2e-50
KMKKNLJM_01850 4.7e-48
KMKKNLJM_01851 3.7e-250 ywqJ S Pre-toxin TG
KMKKNLJM_01852 2e-37 ywqI S Family of unknown function (DUF5344)
KMKKNLJM_01853 1.3e-19 S Domain of unknown function (DUF5082)
KMKKNLJM_01854 4.9e-153 ywqG S Domain of unknown function (DUF1963)
KMKKNLJM_01855 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KMKKNLJM_01856 1.3e-137 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KMKKNLJM_01857 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KMKKNLJM_01858 2e-116 ywqC M biosynthesis protein
KMKKNLJM_01859 1.2e-17
KMKKNLJM_01860 7.8e-307 ywqB S SWIM zinc finger
KMKKNLJM_01861 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KMKKNLJM_01862 1.5e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KMKKNLJM_01863 5.7e-138 glcR K COG1349 Transcriptional regulators of sugar metabolism
KMKKNLJM_01864 4.9e-57 ssbB L Single-stranded DNA-binding protein
KMKKNLJM_01865 3.8e-66 ywpG
KMKKNLJM_01866 4e-66 ywpF S YwpF-like protein
KMKKNLJM_01867 6.7e-84 srtA 3.4.22.70 M Sortase family
KMKKNLJM_01868 0.0 M1-568 M cell wall anchor domain
KMKKNLJM_01869 2.6e-173 M1-574 T Transcriptional regulatory protein, C terminal
KMKKNLJM_01870 0.0 ywpD T PhoQ Sensor
KMKKNLJM_01871 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KMKKNLJM_01872 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KMKKNLJM_01873 7.5e-197 S aspartate phosphatase
KMKKNLJM_01874 1.1e-139 flhP N flagellar basal body
KMKKNLJM_01875 1.7e-124 flhO N flagellar basal body
KMKKNLJM_01876 3.5e-180 mbl D Rod shape-determining protein
KMKKNLJM_01877 3e-44 spoIIID K Stage III sporulation protein D
KMKKNLJM_01878 2.1e-70 ywoH K COG1846 Transcriptional regulators
KMKKNLJM_01879 1.1e-209 ywoG EGP Major facilitator Superfamily
KMKKNLJM_01881 1.3e-225 ywoF P Right handed beta helix region
KMKKNLJM_01882 7.5e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KMKKNLJM_01883 9.1e-240 ywoD EGP Major facilitator superfamily
KMKKNLJM_01884 6.8e-104 phzA Q Isochorismatase family
KMKKNLJM_01885 1.2e-77
KMKKNLJM_01886 2.5e-225 amt P Ammonium transporter
KMKKNLJM_01887 1.6e-58 nrgB K Belongs to the P(II) protein family
KMKKNLJM_01888 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KMKKNLJM_01889 1.7e-72 ywnJ S VanZ like family
KMKKNLJM_01890 2e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KMKKNLJM_01891 1.7e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KMKKNLJM_01892 9.5e-12 ywnC S Family of unknown function (DUF5362)
KMKKNLJM_01893 2.9e-70 ywnF S Family of unknown function (DUF5392)
KMKKNLJM_01894 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMKKNLJM_01895 2.6e-143 mta K transcriptional
KMKKNLJM_01896 1.7e-58 ywnC S Family of unknown function (DUF5362)
KMKKNLJM_01897 5.3e-113 ywnB S NAD(P)H-binding
KMKKNLJM_01898 1.7e-64 ywnA K Transcriptional regulator
KMKKNLJM_01899 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KMKKNLJM_01900 6.5e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KMKKNLJM_01901 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KMKKNLJM_01903 3.8e-11 csbD K CsbD-like
KMKKNLJM_01904 3e-84 ywmF S Peptidase M50
KMKKNLJM_01905 7.9e-104 S response regulator aspartate phosphatase
KMKKNLJM_01906 1.3e-190 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KMKKNLJM_01907 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KMKKNLJM_01909 2.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KMKKNLJM_01910 1.9e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KMKKNLJM_01911 3.5e-175 spoIID D Stage II sporulation protein D
KMKKNLJM_01912 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMKKNLJM_01913 1.4e-133 ywmB S TATA-box binding
KMKKNLJM_01914 1.3e-32 ywzB S membrane
KMKKNLJM_01915 4.1e-86 ywmA
KMKKNLJM_01916 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KMKKNLJM_01917 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KMKKNLJM_01918 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KMKKNLJM_01919 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KMKKNLJM_01920 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMKKNLJM_01921 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KMKKNLJM_01922 1.1e-25 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KMKKNLJM_01923 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KMKKNLJM_01924 1.3e-61 atpI S ATP synthase
KMKKNLJM_01925 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KMKKNLJM_01926 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KMKKNLJM_01927 7.2e-95 ywlG S Belongs to the UPF0340 family
KMKKNLJM_01928 6.4e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KMKKNLJM_01929 3.9e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMKKNLJM_01930 1.7e-91 mntP P Probably functions as a manganese efflux pump
KMKKNLJM_01931 4.4e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KMKKNLJM_01932 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KMKKNLJM_01933 6.1e-112 spoIIR S stage II sporulation protein R
KMKKNLJM_01934 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
KMKKNLJM_01936 7.5e-155 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KMKKNLJM_01937 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KMKKNLJM_01938 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_01939 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KMKKNLJM_01940 8.6e-160 ywkB S Membrane transport protein
KMKKNLJM_01941 0.0 sfcA 1.1.1.38 C malic enzyme
KMKKNLJM_01942 7e-104 tdk 2.7.1.21 F thymidine kinase
KMKKNLJM_01943 1.1e-32 rpmE J Binds the 23S rRNA
KMKKNLJM_01944 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KMKKNLJM_01945 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KMKKNLJM_01946 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KMKKNLJM_01947 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KMKKNLJM_01948 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KMKKNLJM_01949 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KMKKNLJM_01950 6e-91 ywjG S Domain of unknown function (DUF2529)
KMKKNLJM_01951 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KMKKNLJM_01952 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KMKKNLJM_01953 1.4e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KMKKNLJM_01954 0.0 fadF C COG0247 Fe-S oxidoreductase
KMKKNLJM_01955 1.7e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KMKKNLJM_01956 1.2e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KMKKNLJM_01957 2.7e-42 ywjC
KMKKNLJM_01958 2.5e-92 ywjB H RibD C-terminal domain
KMKKNLJM_01959 0.0 ywjA V ABC transporter
KMKKNLJM_01960 4.2e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KMKKNLJM_01961 1.5e-123 narI 1.7.5.1 C nitrate reductase, gamma
KMKKNLJM_01962 1.4e-93 narJ 1.7.5.1 C nitrate reductase
KMKKNLJM_01963 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
KMKKNLJM_01964 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMKKNLJM_01965 4.5e-85 arfM T cyclic nucleotide binding
KMKKNLJM_01966 1.7e-139 ywiC S YwiC-like protein
KMKKNLJM_01967 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KMKKNLJM_01968 1e-213 narK P COG2223 Nitrate nitrite transporter
KMKKNLJM_01969 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KMKKNLJM_01970 4.7e-73 ywiB S protein conserved in bacteria
KMKKNLJM_01971 1e-07 S Bacteriocin subtilosin A
KMKKNLJM_01972 4.9e-270 C Fe-S oxidoreductases
KMKKNLJM_01974 3.3e-132 cbiO V ABC transporter
KMKKNLJM_01975 1.2e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KMKKNLJM_01976 8.5e-218 2.7.1.26, 2.7.7.2 L Peptidase, M16
KMKKNLJM_01977 1.2e-244 L Peptidase, M16
KMKKNLJM_01979 1.7e-238 ywhL CO amine dehydrogenase activity
KMKKNLJM_01980 4.4e-194 ywhK CO amine dehydrogenase activity
KMKKNLJM_01981 8.9e-87 S aspartate phosphatase
KMKKNLJM_01983 2.8e-28 ywhH S Aminoacyl-tRNA editing domain
KMKKNLJM_01984 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KMKKNLJM_01985 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KMKKNLJM_01986 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMKKNLJM_01987 2e-94 ywhD S YwhD family
KMKKNLJM_01988 5.1e-119 ywhC S Peptidase family M50
KMKKNLJM_01989 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KMKKNLJM_01990 3.3e-71 ywhA K Transcriptional regulator
KMKKNLJM_01991 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KMKKNLJM_01993 5.2e-238 mmr U Major Facilitator Superfamily
KMKKNLJM_01994 6.2e-79 yffB K Transcriptional regulator
KMKKNLJM_01995 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
KMKKNLJM_01996 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
KMKKNLJM_01997 3.1e-36 ywzC S Belongs to the UPF0741 family
KMKKNLJM_01998 1e-110 rsfA_1
KMKKNLJM_01999 2.2e-157 ywfM EG EamA-like transporter family
KMKKNLJM_02000 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KMKKNLJM_02001 7.1e-156 cysL K Transcriptional regulator
KMKKNLJM_02002 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KMKKNLJM_02003 3.3e-146 ywfI C May function as heme-dependent peroxidase
KMKKNLJM_02004 7.5e-138 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_02005 7.3e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
KMKKNLJM_02006 7.3e-209 bacE EGP Major facilitator Superfamily
KMKKNLJM_02007 8.8e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KMKKNLJM_02008 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_02009 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KMKKNLJM_02010 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KMKKNLJM_02011 6e-206 ywfA EGP Major facilitator Superfamily
KMKKNLJM_02012 7.4e-250 lysP E amino acid
KMKKNLJM_02013 0.0 rocB E arginine degradation protein
KMKKNLJM_02014 6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMKKNLJM_02015 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KMKKNLJM_02016 1.2e-77
KMKKNLJM_02017 1.3e-86 spsL 5.1.3.13 M Spore Coat
KMKKNLJM_02018 2.9e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KMKKNLJM_02019 8.7e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KMKKNLJM_02020 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KMKKNLJM_02021 1.5e-186 spsG M Spore Coat
KMKKNLJM_02022 3.7e-131 spsF M Spore Coat
KMKKNLJM_02023 3.5e-213 spsE 2.5.1.56 M acid synthase
KMKKNLJM_02024 2.9e-162 spsD 2.3.1.210 K Spore Coat
KMKKNLJM_02025 1.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
KMKKNLJM_02026 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
KMKKNLJM_02027 1e-142 spsA M Spore Coat
KMKKNLJM_02028 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KMKKNLJM_02029 4.3e-59 ywdK S small membrane protein
KMKKNLJM_02030 3.7e-238 ywdJ F Xanthine uracil
KMKKNLJM_02031 1.3e-48 ywdI S Family of unknown function (DUF5327)
KMKKNLJM_02032 6.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KMKKNLJM_02033 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KMKKNLJM_02034 7.2e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KMKKNLJM_02035 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMKKNLJM_02036 2e-28 ywdA
KMKKNLJM_02037 3.7e-292 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KMKKNLJM_02038 7.3e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_02039 1.1e-138 focA P Formate/nitrite transporter
KMKKNLJM_02040 7e-150 sacT K transcriptional antiterminator
KMKKNLJM_02042 0.0 vpr O Belongs to the peptidase S8 family
KMKKNLJM_02043 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_02044 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KMKKNLJM_02045 8.6e-202 rodA D Belongs to the SEDS family
KMKKNLJM_02046 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KMKKNLJM_02047 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KMKKNLJM_02048 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KMKKNLJM_02049 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMKKNLJM_02050 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KMKKNLJM_02051 1e-35 ywzA S membrane
KMKKNLJM_02052 2.2e-298 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KMKKNLJM_02053 3.1e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KMKKNLJM_02054 9.5e-60 gtcA S GtrA-like protein
KMKKNLJM_02055 2.2e-122 ywcC K transcriptional regulator
KMKKNLJM_02057 9.8e-49 ywcB S Protein of unknown function, DUF485
KMKKNLJM_02058 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMKKNLJM_02059 3.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KMKKNLJM_02060 4.9e-224 ywbN P Dyp-type peroxidase family protein
KMKKNLJM_02061 1.2e-184 ycdO P periplasmic lipoprotein involved in iron transport
KMKKNLJM_02062 1e-249 P COG0672 High-affinity Fe2 Pb2 permease
KMKKNLJM_02063 1.2e-112 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KMKKNLJM_02064 1.3e-140 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KMKKNLJM_02065 4.3e-153 ywbI K Transcriptional regulator
KMKKNLJM_02066 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KMKKNLJM_02067 2.3e-111 ywbG M effector of murein hydrolase
KMKKNLJM_02068 1.5e-206 ywbF EGP Major facilitator Superfamily
KMKKNLJM_02069 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KMKKNLJM_02070 4.5e-219 ywbD 2.1.1.191 J Methyltransferase
KMKKNLJM_02071 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KMKKNLJM_02072 4e-119 ywbB S Protein of unknown function (DUF2711)
KMKKNLJM_02073 7.8e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMKKNLJM_02074 1.9e-270 epr 3.4.21.62 O Belongs to the peptidase S8 family
KMKKNLJM_02075 2.6e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_02076 4e-153 sacY K transcriptional antiterminator
KMKKNLJM_02077 4.5e-168 gspA M General stress
KMKKNLJM_02078 2.5e-124 ywaF S Integral membrane protein
KMKKNLJM_02079 4e-87 ywaE K Transcriptional regulator
KMKKNLJM_02080 3e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KMKKNLJM_02081 8.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KMKKNLJM_02082 1.4e-92 K Helix-turn-helix XRE-family like proteins
KMKKNLJM_02083 5.5e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
KMKKNLJM_02084 6.8e-130 ynfM EGP Major facilitator Superfamily
KMKKNLJM_02085 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KMKKNLJM_02086 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KMKKNLJM_02087 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_02088 1.2e-232 dltB M membrane protein involved in D-alanine export
KMKKNLJM_02089 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_02090 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KMKKNLJM_02091 2.8e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_02092 1.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KMKKNLJM_02093 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMKKNLJM_02094 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMKKNLJM_02095 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMKKNLJM_02096 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KMKKNLJM_02097 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KMKKNLJM_02098 1.1e-19 yxzF
KMKKNLJM_02099 1.1e-109 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KMKKNLJM_02100 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KMKKNLJM_02101 7.3e-209 yxlH EGP Major facilitator Superfamily
KMKKNLJM_02102 1.2e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMKKNLJM_02103 4.8e-165 yxlF V ABC transporter, ATP-binding protein
KMKKNLJM_02104 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KMKKNLJM_02105 1.4e-30
KMKKNLJM_02106 3.9e-48 yxlC S Family of unknown function (DUF5345)
KMKKNLJM_02107 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_02108 1.1e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KMKKNLJM_02109 7e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KMKKNLJM_02110 0.0 cydD V ATP-binding protein
KMKKNLJM_02111 1.4e-309 cydD V ATP-binding
KMKKNLJM_02112 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KMKKNLJM_02113 1.4e-267 cydA 1.10.3.14 C oxidase, subunit
KMKKNLJM_02114 1.5e-229 cimH C COG3493 Na citrate symporter
KMKKNLJM_02115 9.4e-311 3.4.24.84 O Peptidase family M48
KMKKNLJM_02117 2.1e-154 yxkH G Polysaccharide deacetylase
KMKKNLJM_02118 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KMKKNLJM_02119 3.5e-163 lrp QT PucR C-terminal helix-turn-helix domain
KMKKNLJM_02120 2.2e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMKKNLJM_02121 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMKKNLJM_02122 1.4e-73 yxkC S Domain of unknown function (DUF4352)
KMKKNLJM_02123 3.9e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KMKKNLJM_02124 2e-77 S Protein of unknown function (DUF1453)
KMKKNLJM_02125 2e-190 yxjM T Signal transduction histidine kinase
KMKKNLJM_02126 3.4e-115 K helix_turn_helix, Lux Regulon
KMKKNLJM_02127 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KMKKNLJM_02130 2.3e-84 yxjI S LURP-one-related
KMKKNLJM_02131 1.6e-218 yxjG 2.1.1.14 E Methionine synthase
KMKKNLJM_02132 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
KMKKNLJM_02133 8.2e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KMKKNLJM_02134 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KMKKNLJM_02135 2e-129 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KMKKNLJM_02136 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
KMKKNLJM_02137 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
KMKKNLJM_02138 4.1e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMKKNLJM_02139 1.2e-104 T Domain of unknown function (DUF4163)
KMKKNLJM_02140 3e-47 yxiS
KMKKNLJM_02141 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KMKKNLJM_02142 6.6e-224 citH C Citrate transporter
KMKKNLJM_02143 4.3e-143 exoK GH16 M licheninase activity
KMKKNLJM_02144 3.1e-150 licT K transcriptional antiterminator
KMKKNLJM_02145 3.1e-111
KMKKNLJM_02146 1.2e-230 yxiO S COG2270 Permeases of the major facilitator superfamily
KMKKNLJM_02147 1.1e-262 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KMKKNLJM_02148 5.2e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KMKKNLJM_02151 1.9e-41 yxiJ S YxiJ-like protein
KMKKNLJM_02152 1.3e-39
KMKKNLJM_02153 1.9e-164 yxxF EG EamA-like transporter family
KMKKNLJM_02154 1.8e-125 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_02155 9.3e-122 1.14.11.45 E 2OG-Fe dioxygenase
KMKKNLJM_02156 1.1e-72 yxiE T Belongs to the universal stress protein A family
KMKKNLJM_02157 1.8e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMKKNLJM_02158 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_02159 5.5e-53
KMKKNLJM_02160 1e-213 S nuclease activity
KMKKNLJM_02161 2.3e-38 yxiC S Family of unknown function (DUF5344)
KMKKNLJM_02162 1e-20 S Domain of unknown function (DUF5082)
KMKKNLJM_02163 2.8e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KMKKNLJM_02164 4.9e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
KMKKNLJM_02165 1.7e-96 S GTP binding
KMKKNLJM_02166 4.9e-77 L NgoFVII restriction endonuclease
KMKKNLJM_02167 1.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KMKKNLJM_02168 9.4e-10 S Oxidoreductase
KMKKNLJM_02170 4.2e-13 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KMKKNLJM_02171 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KMKKNLJM_02172 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
KMKKNLJM_02173 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KMKKNLJM_02174 1.2e-233 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KMKKNLJM_02175 4.4e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KMKKNLJM_02176 3.4e-250 lysP E amino acid
KMKKNLJM_02177 3.9e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KMKKNLJM_02178 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KMKKNLJM_02179 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KMKKNLJM_02180 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KMKKNLJM_02181 2e-152 yxxB S Domain of Unknown Function (DUF1206)
KMKKNLJM_02182 1.1e-195 eutH E Ethanolamine utilisation protein, EutH
KMKKNLJM_02183 3.6e-249 yxeQ S MmgE/PrpD family
KMKKNLJM_02184 5.5e-214 yxeP 3.5.1.47 E hydrolase activity
KMKKNLJM_02185 5.9e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KMKKNLJM_02186 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
KMKKNLJM_02187 1.2e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
KMKKNLJM_02188 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_02189 2e-252 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_02190 2.6e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KMKKNLJM_02191 5.2e-150 yidA S hydrolases of the HAD superfamily
KMKKNLJM_02194 1.3e-20 yxeE
KMKKNLJM_02195 5.6e-16 yxeD
KMKKNLJM_02196 8.5e-69
KMKKNLJM_02197 6.6e-176 fhuD P ABC transporter
KMKKNLJM_02198 1.3e-57 yxeA S Protein of unknown function (DUF1093)
KMKKNLJM_02199 0.0 yxdM V ABC transporter (permease)
KMKKNLJM_02200 3.7e-137 yxdL V ABC transporter, ATP-binding protein
KMKKNLJM_02201 6.9e-181 T PhoQ Sensor
KMKKNLJM_02202 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_02203 6e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KMKKNLJM_02204 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KMKKNLJM_02205 3e-167 iolH G Xylose isomerase-like TIM barrel
KMKKNLJM_02206 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KMKKNLJM_02207 9.6e-234 iolF EGP Major facilitator Superfamily
KMKKNLJM_02208 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KMKKNLJM_02209 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KMKKNLJM_02210 8.7e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KMKKNLJM_02211 3.5e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KMKKNLJM_02212 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMKKNLJM_02213 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KMKKNLJM_02214 7e-175 iolS C Aldo keto reductase
KMKKNLJM_02216 5.4e-47 yxcD S Protein of unknown function (DUF2653)
KMKKNLJM_02217 2.5e-90 S CGNR zinc finger
KMKKNLJM_02218 8.9e-79 T HPP family
KMKKNLJM_02219 1.5e-245 csbC EGP Major facilitator Superfamily
KMKKNLJM_02220 0.0 htpG O Molecular chaperone. Has ATPase activity
KMKKNLJM_02222 3.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_02223 1.4e-196 yxbF K Bacterial regulatory proteins, tetR family
KMKKNLJM_02224 1.7e-246 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KMKKNLJM_02226 3.7e-91 S PQQ-like domain
KMKKNLJM_02227 1.1e-63 S Family of unknown function (DUF5391)
KMKKNLJM_02228 1.4e-75 yxaI S membrane protein domain
KMKKNLJM_02229 4.6e-227 P Protein of unknown function (DUF418)
KMKKNLJM_02230 6.4e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
KMKKNLJM_02231 2.7e-100 yxaF K Transcriptional regulator
KMKKNLJM_02232 7.5e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_02233 2.2e-70 yxaD K helix_turn_helix multiple antibiotic resistance protein
KMKKNLJM_02234 5.2e-50 S LrgA family
KMKKNLJM_02235 2.2e-117 yxaC M effector of murein hydrolase
KMKKNLJM_02236 5.9e-191 yxaB GM Polysaccharide pyruvyl transferase
KMKKNLJM_02237 1.2e-205 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KMKKNLJM_02238 7.3e-127 gntR K transcriptional
KMKKNLJM_02239 1.7e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KMKKNLJM_02240 3.8e-230 gntP EG COG2610 H gluconate symporter and related permeases
KMKKNLJM_02241 4.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KMKKNLJM_02242 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KMKKNLJM_02243 3.8e-287 ahpF O Alkyl hydroperoxide reductase
KMKKNLJM_02244 8.1e-188 wgaE S Polysaccharide pyruvyl transferase
KMKKNLJM_02245 2.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMKKNLJM_02246 3.2e-25 bglF G phosphotransferase system
KMKKNLJM_02247 1.5e-18 bglF G phosphotransferase system
KMKKNLJM_02248 1.9e-124 yydK K Transcriptional regulator
KMKKNLJM_02249 7.6e-13
KMKKNLJM_02250 8.9e-117 S ABC-2 family transporter protein
KMKKNLJM_02251 1.6e-109 prrC P ABC transporter
KMKKNLJM_02252 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KMKKNLJM_02255 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KMKKNLJM_02256 1.1e-09 S YyzF-like protein
KMKKNLJM_02257 5.7e-68
KMKKNLJM_02258 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KMKKNLJM_02260 2.8e-30 yycQ S Protein of unknown function (DUF2651)
KMKKNLJM_02261 3.5e-208 yycP
KMKKNLJM_02262 2.1e-129 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KMKKNLJM_02263 1.1e-83 yycN 2.3.1.128 K Acetyltransferase
KMKKNLJM_02264 1.5e-187 S aspartate phosphatase
KMKKNLJM_02266 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KMKKNLJM_02267 1.4e-254 rocE E amino acid
KMKKNLJM_02268 7.3e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KMKKNLJM_02269 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KMKKNLJM_02270 3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMKKNLJM_02271 1.5e-94 K PFAM response regulator receiver
KMKKNLJM_02272 8.8e-74 S Peptidase propeptide and YPEB domain
KMKKNLJM_02273 2.1e-16 S Peptidase propeptide and YPEB domain
KMKKNLJM_02274 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMKKNLJM_02275 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KMKKNLJM_02276 7.3e-155 yycI S protein conserved in bacteria
KMKKNLJM_02277 2.9e-257 yycH S protein conserved in bacteria
KMKKNLJM_02278 0.0 vicK 2.7.13.3 T Histidine kinase
KMKKNLJM_02279 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_02284 5.1e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KMKKNLJM_02285 2.6e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_02286 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KMKKNLJM_02287 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KMKKNLJM_02289 1.9e-15 yycC K YycC-like protein
KMKKNLJM_02290 2.5e-220 yeaN P COG2807 Cyanate permease
KMKKNLJM_02291 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMKKNLJM_02292 2.2e-73 rplI J binds to the 23S rRNA
KMKKNLJM_02293 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KMKKNLJM_02294 1.9e-159 yybS S membrane
KMKKNLJM_02296 3.9e-84 cotF M Spore coat protein
KMKKNLJM_02297 1.7e-66 ydeP3 K Transcriptional regulator
KMKKNLJM_02298 3.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KMKKNLJM_02299 5.6e-61
KMKKNLJM_02301 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KMKKNLJM_02302 1.7e-110 K TipAS antibiotic-recognition domain
KMKKNLJM_02303 6.9e-123
KMKKNLJM_02304 2.3e-66 yybH S SnoaL-like domain
KMKKNLJM_02305 1.4e-121 yybG S Pentapeptide repeat-containing protein
KMKKNLJM_02306 2.3e-218 ynfM EGP Major facilitator Superfamily
KMKKNLJM_02307 4.5e-163 yybE K Transcriptional regulator
KMKKNLJM_02308 5e-78 yjcF S Acetyltransferase (GNAT) domain
KMKKNLJM_02309 1.6e-74 yybC
KMKKNLJM_02310 3.6e-125 S Metallo-beta-lactamase superfamily
KMKKNLJM_02311 5.6e-77 yybA 2.3.1.57 K transcriptional
KMKKNLJM_02312 1.4e-72 yjcF S Acetyltransferase (GNAT) domain
KMKKNLJM_02313 2.1e-92 yyaS S Membrane
KMKKNLJM_02315 2.3e-65 S Putative inner membrane exporter, YdcZ
KMKKNLJM_02316 7.5e-63 S Putative inner membrane exporter, YdcZ
KMKKNLJM_02317 9.1e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
KMKKNLJM_02318 2.5e-60 yyaN K MerR HTH family regulatory protein
KMKKNLJM_02319 6.3e-160 yyaM EG EamA-like transporter family
KMKKNLJM_02320 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KMKKNLJM_02321 1.5e-166 yyaK S CAAX protease self-immunity
KMKKNLJM_02322 3.2e-245 EGP Major facilitator superfamily
KMKKNLJM_02323 6.8e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KMKKNLJM_02324 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_02325 2.6e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KMKKNLJM_02326 2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
KMKKNLJM_02327 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KMKKNLJM_02328 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KMKKNLJM_02329 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KMKKNLJM_02330 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KMKKNLJM_02331 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMKKNLJM_02332 2.3e-33 yyzM S protein conserved in bacteria
KMKKNLJM_02333 3.1e-176 yyaD S Membrane
KMKKNLJM_02334 1.6e-111 yyaC S Sporulation protein YyaC
KMKKNLJM_02335 2.1e-149 spo0J K Belongs to the ParB family
KMKKNLJM_02336 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KMKKNLJM_02337 2.8e-73 S Bacterial PH domain
KMKKNLJM_02338 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KMKKNLJM_02339 7e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KMKKNLJM_02340 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KMKKNLJM_02341 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KMKKNLJM_02342 6.5e-108 jag S single-stranded nucleic acid binding R3H
KMKKNLJM_02343 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KMKKNLJM_02344 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KMKKNLJM_02345 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KMKKNLJM_02346 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KMKKNLJM_02347 2.4e-33 yaaA S S4 domain
KMKKNLJM_02348 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KMKKNLJM_02349 1.8e-37 yaaB S Domain of unknown function (DUF370)
KMKKNLJM_02350 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMKKNLJM_02351 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KMKKNLJM_02356 7.8e-08
KMKKNLJM_02364 2e-08
KMKKNLJM_02368 1.7e-142 spo0M S COG4326 Sporulation control protein
KMKKNLJM_02369 4.4e-26
KMKKNLJM_02370 3.6e-125 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KMKKNLJM_02371 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KMKKNLJM_02372 3.4e-263 ygaK C Berberine and berberine like
KMKKNLJM_02374 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KMKKNLJM_02375 3.9e-146 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KMKKNLJM_02376 1.6e-169 ssuA M Sulfonate ABC transporter
KMKKNLJM_02377 6.1e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KMKKNLJM_02378 1.2e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KMKKNLJM_02380 1.9e-40 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMKKNLJM_02381 2.6e-77 ygaO
KMKKNLJM_02382 4.4e-29 K Transcriptional regulator
KMKKNLJM_02384 1.3e-111 yhzB S B3/4 domain
KMKKNLJM_02385 1.7e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KMKKNLJM_02386 2.4e-175 yhbB S Putative amidase domain
KMKKNLJM_02387 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KMKKNLJM_02388 7.9e-109 yhbD K Protein of unknown function (DUF4004)
KMKKNLJM_02389 1.6e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KMKKNLJM_02390 1e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KMKKNLJM_02391 0.0 prkA T Ser protein kinase
KMKKNLJM_02392 2.5e-225 yhbH S Belongs to the UPF0229 family
KMKKNLJM_02393 2.2e-76 yhbI K DNA-binding transcription factor activity
KMKKNLJM_02394 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KMKKNLJM_02395 3.1e-271 yhcA EGP Major facilitator Superfamily
KMKKNLJM_02396 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KMKKNLJM_02397 2.8e-37 yhcC
KMKKNLJM_02398 1.3e-54
KMKKNLJM_02399 1.9e-59 yhcF K Transcriptional regulator
KMKKNLJM_02400 1.6e-46 yhcG V ABC transporter, ATP-binding protein
KMKKNLJM_02401 8e-58 yhcG V ABC transporter, ATP-binding protein
KMKKNLJM_02402 7.7e-166 yhcH V ABC transporter, ATP-binding protein
KMKKNLJM_02403 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMKKNLJM_02404 1e-30 cspB K Cold-shock protein
KMKKNLJM_02405 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
KMKKNLJM_02406 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KMKKNLJM_02407 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMKKNLJM_02408 1.1e-40 yhcM
KMKKNLJM_02409 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMKKNLJM_02410 2.5e-167 yhcP
KMKKNLJM_02411 5.2e-100 yhcQ M Spore coat protein
KMKKNLJM_02412 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KMKKNLJM_02413 5.4e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KMKKNLJM_02414 3.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMKKNLJM_02415 2.1e-67 yhcU S Family of unknown function (DUF5365)
KMKKNLJM_02416 9.9e-68 yhcV S COG0517 FOG CBS domain
KMKKNLJM_02417 4.6e-120 yhcW 5.4.2.6 S hydrolase
KMKKNLJM_02418 4.6e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMKKNLJM_02419 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMKKNLJM_02420 1.2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KMKKNLJM_02421 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KMKKNLJM_02422 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KMKKNLJM_02423 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KMKKNLJM_02424 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KMKKNLJM_02425 2.7e-213 yhcY 2.7.13.3 T Histidine kinase
KMKKNLJM_02426 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_02427 3.6e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KMKKNLJM_02428 1.2e-38 yhdB S YhdB-like protein
KMKKNLJM_02429 1.8e-53 yhdC S Protein of unknown function (DUF3889)
KMKKNLJM_02430 2.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMKKNLJM_02431 1e-75 nsrR K Transcriptional regulator
KMKKNLJM_02432 3.1e-236 ygxB M Conserved TM helix
KMKKNLJM_02433 2.1e-276 ycgB S Stage V sporulation protein R
KMKKNLJM_02434 4.7e-252 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KMKKNLJM_02435 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KMKKNLJM_02436 3.8e-162 citR K Transcriptional regulator
KMKKNLJM_02437 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
KMKKNLJM_02438 9.2e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_02439 3.4e-250 yhdG E amino acid
KMKKNLJM_02440 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KMKKNLJM_02441 1.7e-268 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_02442 2.6e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_02443 8.1e-45 yhdK S Sigma-M inhibitor protein
KMKKNLJM_02444 6.6e-201 yhdL S Sigma factor regulator N-terminal
KMKKNLJM_02445 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_02446 4.4e-191 yhdN C Aldo keto reductase
KMKKNLJM_02447 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KMKKNLJM_02448 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KMKKNLJM_02449 4.7e-74 cueR K transcriptional
KMKKNLJM_02450 2.8e-221 yhdR 2.6.1.1 E Aminotransferase
KMKKNLJM_02451 3.3e-245 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KMKKNLJM_02452 1.7e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMKKNLJM_02453 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KMKKNLJM_02454 2.3e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMKKNLJM_02456 5.6e-203 yhdY M Mechanosensitive ion channel
KMKKNLJM_02457 5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KMKKNLJM_02458 2.1e-146 yheN G deacetylase
KMKKNLJM_02459 9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KMKKNLJM_02460 1.3e-230 nhaC C Na H antiporter
KMKKNLJM_02461 3.4e-84 nhaX T Belongs to the universal stress protein A family
KMKKNLJM_02462 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMKKNLJM_02463 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMKKNLJM_02464 1.3e-108 yheG GM NAD(P)H-binding
KMKKNLJM_02465 6.3e-28 sspB S spore protein
KMKKNLJM_02466 1.3e-36 yheE S Family of unknown function (DUF5342)
KMKKNLJM_02467 5.7e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KMKKNLJM_02468 4.3e-216 yheC HJ YheC/D like ATP-grasp
KMKKNLJM_02469 2.2e-202 yheB S Belongs to the UPF0754 family
KMKKNLJM_02470 9.5e-48 yheA S Belongs to the UPF0342 family
KMKKNLJM_02471 2.2e-204 yhaZ L DNA alkylation repair enzyme
KMKKNLJM_02472 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KMKKNLJM_02473 1.9e-291 hemZ H coproporphyrinogen III oxidase
KMKKNLJM_02474 1.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
KMKKNLJM_02475 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KMKKNLJM_02477 5.5e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
KMKKNLJM_02478 2.4e-26 S YhzD-like protein
KMKKNLJM_02479 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KMKKNLJM_02480 1.2e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KMKKNLJM_02481 1.8e-223 yhaO L DNA repair exonuclease
KMKKNLJM_02482 0.0 yhaN L AAA domain
KMKKNLJM_02483 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KMKKNLJM_02484 1.6e-21 yhaL S Sporulation protein YhaL
KMKKNLJM_02485 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KMKKNLJM_02486 8.7e-90 yhaK S Putative zincin peptidase
KMKKNLJM_02487 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KMKKNLJM_02488 1e-113 hpr K Negative regulator of protease production and sporulation
KMKKNLJM_02489 7e-39 yhaH S YtxH-like protein
KMKKNLJM_02490 3.6e-80 trpP S Tryptophan transporter TrpP
KMKKNLJM_02491 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KMKKNLJM_02492 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KMKKNLJM_02493 8.8e-136 ecsA V transporter (ATP-binding protein)
KMKKNLJM_02494 9.2e-215 ecsB U ABC transporter
KMKKNLJM_02495 6.9e-114 ecsC S EcsC protein family
KMKKNLJM_02496 2.8e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KMKKNLJM_02497 1.6e-231 yhfA C membrane
KMKKNLJM_02498 1.4e-15 1.15.1.2 C Rubrerythrin
KMKKNLJM_02499 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KMKKNLJM_02500 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KMKKNLJM_02501 2.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KMKKNLJM_02502 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KMKKNLJM_02503 6.5e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KMKKNLJM_02504 5.4e-101 yhgD K Transcriptional regulator
KMKKNLJM_02505 4.3e-229 yhgE S YhgE Pip N-terminal domain protein
KMKKNLJM_02506 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMKKNLJM_02507 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
KMKKNLJM_02508 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KMKKNLJM_02509 1.1e-71 3.4.13.21 S ASCH
KMKKNLJM_02510 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMKKNLJM_02511 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KMKKNLJM_02512 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KMKKNLJM_02513 2.9e-111 yhfK GM NmrA-like family
KMKKNLJM_02514 1e-298 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KMKKNLJM_02515 1.9e-65 yhfM
KMKKNLJM_02516 1e-240 yhfN 3.4.24.84 O Peptidase M48
KMKKNLJM_02517 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KMKKNLJM_02518 3.6e-76 VY92_01935 K acetyltransferase
KMKKNLJM_02519 3.1e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
KMKKNLJM_02520 4.3e-159 yfmC M Periplasmic binding protein
KMKKNLJM_02521 3.5e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KMKKNLJM_02522 1.4e-195 vraB 2.3.1.9 I Belongs to the thiolase family
KMKKNLJM_02523 2.3e-273 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KMKKNLJM_02524 1.9e-90 bioY S BioY family
KMKKNLJM_02525 2.7e-180 hemAT NT chemotaxis protein
KMKKNLJM_02526 8.8e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KMKKNLJM_02527 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_02528 1.3e-32 yhzC S IDEAL
KMKKNLJM_02529 4.2e-109 comK K Competence transcription factor
KMKKNLJM_02530 1.4e-167 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_02531 8.1e-39 yhjA S Excalibur calcium-binding domain
KMKKNLJM_02532 8.8e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMKKNLJM_02533 4.5e-26 yhjC S Protein of unknown function (DUF3311)
KMKKNLJM_02534 2.5e-59 yhjD
KMKKNLJM_02535 9.1e-110 yhjE S SNARE associated Golgi protein
KMKKNLJM_02536 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KMKKNLJM_02537 2.1e-277 yhjG CH FAD binding domain
KMKKNLJM_02538 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KMKKNLJM_02541 2.5e-212 glcP G Major Facilitator Superfamily
KMKKNLJM_02542 2.7e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KMKKNLJM_02543 5.8e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KMKKNLJM_02544 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KMKKNLJM_02545 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
KMKKNLJM_02546 4.2e-201 abrB S membrane
KMKKNLJM_02547 4.9e-213 EGP Transmembrane secretion effector
KMKKNLJM_02548 0.0 S Sugar transport-related sRNA regulator N-term
KMKKNLJM_02549 6.4e-78 yhjR S Rubrerythrin
KMKKNLJM_02550 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KMKKNLJM_02551 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KMKKNLJM_02552 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KMKKNLJM_02553 0.0 sbcC L COG0419 ATPase involved in DNA repair
KMKKNLJM_02554 1.8e-47 yisB V COG1403 Restriction endonuclease
KMKKNLJM_02555 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KMKKNLJM_02556 5.3e-63 gerPE S Spore germination protein GerPE
KMKKNLJM_02557 1.1e-23 gerPD S Spore germination protein
KMKKNLJM_02558 5.3e-54 gerPC S Spore germination protein
KMKKNLJM_02559 4e-34 gerPB S cell differentiation
KMKKNLJM_02560 1.9e-33 gerPA S Spore germination protein
KMKKNLJM_02561 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KMKKNLJM_02562 6.5e-173 cotH M Spore Coat
KMKKNLJM_02563 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KMKKNLJM_02564 3.9e-57 yisL S UPF0344 protein
KMKKNLJM_02565 0.0 wprA O Belongs to the peptidase S8 family
KMKKNLJM_02566 2.2e-99 yisN S Protein of unknown function (DUF2777)
KMKKNLJM_02567 0.0 asnO 6.3.5.4 E Asparagine synthase
KMKKNLJM_02568 1.3e-116 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KMKKNLJM_02569 1.1e-240 yisQ V Mate efflux family protein
KMKKNLJM_02570 1.2e-160 yisR K Transcriptional regulator
KMKKNLJM_02571 1.5e-183 purR K helix_turn _helix lactose operon repressor
KMKKNLJM_02572 8.8e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KMKKNLJM_02573 1.8e-92 yisT S DinB family
KMKKNLJM_02574 3e-105 argO S Lysine exporter protein LysE YggA
KMKKNLJM_02575 2.3e-273 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_02576 1.2e-35 mcbG S Pentapeptide repeats (9 copies)
KMKKNLJM_02577 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMKKNLJM_02578 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KMKKNLJM_02579 1.1e-228 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KMKKNLJM_02580 1.3e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KMKKNLJM_02581 2.4e-119 comB 3.1.3.71 H Belongs to the ComB family
KMKKNLJM_02582 3.5e-140 yitD 4.4.1.19 S synthase
KMKKNLJM_02583 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KMKKNLJM_02584 1e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KMKKNLJM_02585 1.5e-228 yitG EGP Major facilitator Superfamily
KMKKNLJM_02586 1.3e-156 yitH K Acetyltransferase (GNAT) domain
KMKKNLJM_02587 1.6e-71 yjcF S Acetyltransferase (GNAT) domain
KMKKNLJM_02588 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KMKKNLJM_02589 1.9e-54 yajQ S Belongs to the UPF0234 family
KMKKNLJM_02590 3.4e-160 cvfB S protein conserved in bacteria
KMKKNLJM_02591 8.5e-94
KMKKNLJM_02592 2.3e-170
KMKKNLJM_02593 1.5e-97 S Sporulation delaying protein SdpA
KMKKNLJM_02594 1e-57 K Transcriptional regulator PadR-like family
KMKKNLJM_02595 2.9e-94
KMKKNLJM_02596 1.4e-44 yitR S Domain of unknown function (DUF3784)
KMKKNLJM_02597 3.2e-308 nprB 3.4.24.28 E Peptidase M4
KMKKNLJM_02598 9.3e-158 yitS S protein conserved in bacteria
KMKKNLJM_02599 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KMKKNLJM_02600 5e-73 ipi S Intracellular proteinase inhibitor
KMKKNLJM_02601 1.2e-17 S Protein of unknown function (DUF3813)
KMKKNLJM_02603 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KMKKNLJM_02604 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KMKKNLJM_02605 1.4e-50 yitW S metal-sulfur cluster biosynthetic enzyme
KMKKNLJM_02606 1.5e-22 pilT S Proteolipid membrane potential modulator
KMKKNLJM_02607 9.8e-269 yitY C D-arabinono-1,4-lactone oxidase
KMKKNLJM_02608 1.7e-88 norB G Major Facilitator Superfamily
KMKKNLJM_02609 4.7e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KMKKNLJM_02610 2.2e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KMKKNLJM_02611 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KMKKNLJM_02612 7.8e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KMKKNLJM_02613 7.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KMKKNLJM_02614 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KMKKNLJM_02615 8.6e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KMKKNLJM_02616 9.5e-28 yjzC S YjzC-like protein
KMKKNLJM_02617 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KMKKNLJM_02618 1.1e-141 yjaU I carboxylic ester hydrolase activity
KMKKNLJM_02619 5.3e-101 yjaV
KMKKNLJM_02620 2.5e-183 med S Transcriptional activator protein med
KMKKNLJM_02621 7.3e-26 comZ S ComZ
KMKKNLJM_02622 5e-21 yjzB
KMKKNLJM_02623 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KMKKNLJM_02624 5.2e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMKKNLJM_02625 1.6e-148 yjaZ O Zn-dependent protease
KMKKNLJM_02626 1.5e-183 appD P Belongs to the ABC transporter superfamily
KMKKNLJM_02627 3.6e-185 appF E Belongs to the ABC transporter superfamily
KMKKNLJM_02628 2.4e-287 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KMKKNLJM_02629 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02630 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02632 5e-147 yjbA S Belongs to the UPF0736 family
KMKKNLJM_02633 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KMKKNLJM_02634 0.0 oppA E ABC transporter substrate-binding protein
KMKKNLJM_02635 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02636 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02637 6.8e-198 oppD P Belongs to the ABC transporter superfamily
KMKKNLJM_02638 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KMKKNLJM_02639 5.3e-210 yjbB EGP Major Facilitator Superfamily
KMKKNLJM_02640 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_02641 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KMKKNLJM_02642 6e-112 yjbE P Integral membrane protein TerC family
KMKKNLJM_02643 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KMKKNLJM_02644 3.7e-218 yjbF S Competence protein
KMKKNLJM_02645 0.0 pepF E oligoendopeptidase F
KMKKNLJM_02646 1.8e-20
KMKKNLJM_02648 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KMKKNLJM_02649 3.7e-72 yjbI S Bacterial-like globin
KMKKNLJM_02650 1.4e-88 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KMKKNLJM_02651 1.2e-100 yjbK S protein conserved in bacteria
KMKKNLJM_02652 7.1e-62 yjbL S Belongs to the UPF0738 family
KMKKNLJM_02653 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KMKKNLJM_02654 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KMKKNLJM_02655 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMKKNLJM_02656 2.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KMKKNLJM_02657 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KMKKNLJM_02658 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KMKKNLJM_02659 1.6e-106 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KMKKNLJM_02660 1.7e-215 thiO 1.4.3.19 E Glycine oxidase
KMKKNLJM_02661 1.5e-29 thiS H thiamine diphosphate biosynthetic process
KMKKNLJM_02662 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KMKKNLJM_02663 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMKKNLJM_02664 6.9e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KMKKNLJM_02665 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KMKKNLJM_02666 5.9e-54 yjbX S Spore coat protein
KMKKNLJM_02667 5.2e-83 cotZ S Spore coat protein
KMKKNLJM_02668 3.4e-96 cotY S Spore coat protein Z
KMKKNLJM_02669 6.4e-77 cotX S Spore Coat Protein X and V domain
KMKKNLJM_02670 8.5e-32 cotW
KMKKNLJM_02671 2.3e-55 cotV S Spore Coat Protein X and V domain
KMKKNLJM_02672 4.3e-56 yjcA S Protein of unknown function (DUF1360)
KMKKNLJM_02675 2.9e-38 spoVIF S Stage VI sporulation protein F
KMKKNLJM_02676 0.0 yjcD 3.6.4.12 L DNA helicase
KMKKNLJM_02677 1e-30
KMKKNLJM_02678 2.4e-39 S LXG domain of WXG superfamily
KMKKNLJM_02679 4.3e-48
KMKKNLJM_02680 1.4e-69 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_02681 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KMKKNLJM_02682 1.5e-135 yjcH P COG2382 Enterochelin esterase and related enzymes
KMKKNLJM_02683 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMKKNLJM_02684 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KMKKNLJM_02685 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
KMKKNLJM_02686 9.5e-209 yjcL S Protein of unknown function (DUF819)
KMKKNLJM_02688 1.3e-48
KMKKNLJM_02689 1.9e-126 M nucleic acid phosphodiester bond hydrolysis
KMKKNLJM_02690 7.4e-70 KLT Protein tyrosine kinase
KMKKNLJM_02692 3.4e-179 S response regulator aspartate phosphatase
KMKKNLJM_02693 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
KMKKNLJM_02694 4.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_02696 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KMKKNLJM_02697 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KMKKNLJM_02698 4.5e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
KMKKNLJM_02699 2.2e-48 yjdF S Protein of unknown function (DUF2992)
KMKKNLJM_02700 2.9e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KMKKNLJM_02702 6.4e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KMKKNLJM_02703 7.1e-29 S Domain of unknown function (DUF4177)
KMKKNLJM_02704 1e-51 yjdJ S Domain of unknown function (DUF4306)
KMKKNLJM_02705 5.6e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMKKNLJM_02707 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
KMKKNLJM_02708 1.8e-81 S Protein of unknown function (DUF2690)
KMKKNLJM_02709 2.3e-20 yjfB S Putative motility protein
KMKKNLJM_02710 2.1e-168 yjfC O Predicted Zn-dependent protease (DUF2268)
KMKKNLJM_02711 4.9e-34 T PhoQ Sensor
KMKKNLJM_02712 4.4e-103 yjgB S Domain of unknown function (DUF4309)
KMKKNLJM_02713 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KMKKNLJM_02714 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KMKKNLJM_02715 2e-10 S Domain of unknown function (DUF4352)
KMKKNLJM_02716 2.5e-112 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KMKKNLJM_02718 1.2e-222 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KMKKNLJM_02719 9.4e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMKKNLJM_02720 8.2e-30
KMKKNLJM_02721 1.7e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KMKKNLJM_02722 2.1e-121 ybbM S transport system, permease component
KMKKNLJM_02723 4.4e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KMKKNLJM_02724 9.8e-91 yjlB S Cupin domain
KMKKNLJM_02725 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KMKKNLJM_02726 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KMKKNLJM_02727 2.3e-278 uxaC 5.3.1.12 G glucuronate isomerase
KMKKNLJM_02728 9.2e-248 yjmB G symporter YjmB
KMKKNLJM_02729 1.2e-188 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KMKKNLJM_02730 4.2e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KMKKNLJM_02731 7.5e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KMKKNLJM_02732 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KMKKNLJM_02733 4.1e-226 exuT G Sugar (and other) transporter
KMKKNLJM_02734 6.8e-184 exuR K transcriptional
KMKKNLJM_02735 1.4e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KMKKNLJM_02736 3.1e-281 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KMKKNLJM_02737 7.4e-130 MA20_18170 S membrane transporter protein
KMKKNLJM_02738 2.3e-78 yjoA S DinB family
KMKKNLJM_02739 1.4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KMKKNLJM_02740 1e-212 S response regulator aspartate phosphatase
KMKKNLJM_02742 2.4e-40 S YCII-related domain
KMKKNLJM_02743 8e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KMKKNLJM_02744 5.2e-60 yjqA S Bacterial PH domain
KMKKNLJM_02745 2.1e-111 yjqB S Pfam:DUF867
KMKKNLJM_02746 4.4e-160 ydbD P Catalase
KMKKNLJM_02747 2.3e-110 xkdA E IrrE N-terminal-like domain
KMKKNLJM_02748 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KMKKNLJM_02750 5.9e-157 xkdB K sequence-specific DNA binding
KMKKNLJM_02751 9.2e-118 xkdC L Bacterial dnaA protein
KMKKNLJM_02754 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KMKKNLJM_02755 3.8e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KMKKNLJM_02756 5.3e-139 xtmA L phage terminase small subunit
KMKKNLJM_02757 3.4e-252 xtmB S phage terminase, large subunit
KMKKNLJM_02758 3.4e-280 yqbA S portal protein
KMKKNLJM_02759 5.9e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KMKKNLJM_02760 5.8e-169 xkdG S Phage capsid family
KMKKNLJM_02761 6.7e-63 yqbG S Protein of unknown function (DUF3199)
KMKKNLJM_02762 7.3e-64 yqbH S Domain of unknown function (DUF3599)
KMKKNLJM_02763 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
KMKKNLJM_02764 9.3e-77 xkdJ
KMKKNLJM_02765 9.3e-256 xkdK S Phage tail sheath C-terminal domain
KMKKNLJM_02766 1e-75 xkdM S Phage tail tube protein
KMKKNLJM_02767 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
KMKKNLJM_02768 2.3e-275 xkdO L Transglycosylase SLT domain
KMKKNLJM_02769 2.7e-118 xkdP S Lysin motif
KMKKNLJM_02770 3.1e-181 yqbQ 3.2.1.96 G NLP P60 protein
KMKKNLJM_02771 1e-38 xkdR S Protein of unknown function (DUF2577)
KMKKNLJM_02772 4.1e-69 xkdS S Protein of unknown function (DUF2634)
KMKKNLJM_02773 1.9e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KMKKNLJM_02774 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KMKKNLJM_02775 8.7e-41
KMKKNLJM_02776 1.6e-178
KMKKNLJM_02777 2.7e-44 xkdW S XkdW protein
KMKKNLJM_02778 5.5e-22 xkdX
KMKKNLJM_02779 7.5e-152 xepA
KMKKNLJM_02780 6.2e-39 xhlA S Haemolysin XhlA
KMKKNLJM_02781 2.7e-39 xhlB S SPP1 phage holin
KMKKNLJM_02782 7.7e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMKKNLJM_02783 6.7e-23 spoIISB S Stage II sporulation protein SB
KMKKNLJM_02784 5.2e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KMKKNLJM_02785 5.8e-175 pit P phosphate transporter
KMKKNLJM_02786 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KMKKNLJM_02787 4.7e-233 steT E amino acid
KMKKNLJM_02788 3e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KMKKNLJM_02790 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KMKKNLJM_02791 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMKKNLJM_02792 2.6e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KMKKNLJM_02793 6.3e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KMKKNLJM_02794 3.3e-152 dppA E D-aminopeptidase
KMKKNLJM_02795 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02796 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KMKKNLJM_02797 2.7e-188 dppD P Belongs to the ABC transporter superfamily
KMKKNLJM_02798 0.0 dppE E ABC transporter substrate-binding protein
KMKKNLJM_02800 7.6e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KMKKNLJM_02801 1.1e-198 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KMKKNLJM_02802 1.5e-169 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KMKKNLJM_02803 8.5e-187 ykfD E Belongs to the ABC transporter superfamily
KMKKNLJM_02804 1.2e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
KMKKNLJM_02805 3.2e-158 ykgA E Amidinotransferase
KMKKNLJM_02806 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KMKKNLJM_02807 4e-223 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KMKKNLJM_02808 5e-10
KMKKNLJM_02809 1.5e-127 ykjA S Protein of unknown function (DUF421)
KMKKNLJM_02810 2e-97 ykkA S Protein of unknown function (DUF664)
KMKKNLJM_02811 3.6e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMKKNLJM_02812 1.7e-54 ykkC P Multidrug resistance protein
KMKKNLJM_02813 9.1e-50 ykkD P Multidrug resistance protein
KMKKNLJM_02814 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KMKKNLJM_02815 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KMKKNLJM_02816 1.5e-225 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KMKKNLJM_02817 4.8e-70 ohrA O Organic hydroperoxide resistance protein
KMKKNLJM_02818 4.4e-74 ohrR K COG1846 Transcriptional regulators
KMKKNLJM_02819 8.4e-72 ohrB O Organic hydroperoxide resistance protein
KMKKNLJM_02820 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KMKKNLJM_02821 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KMKKNLJM_02822 1.5e-175 isp O Belongs to the peptidase S8 family
KMKKNLJM_02823 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMKKNLJM_02824 3.8e-134 ykoC P Cobalt transport protein
KMKKNLJM_02825 7.5e-305 P ABC transporter, ATP-binding protein
KMKKNLJM_02826 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KMKKNLJM_02827 5.1e-110 ykoF S YKOF-related Family
KMKKNLJM_02828 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_02829 1.6e-239 ykoH 2.7.13.3 T Histidine kinase
KMKKNLJM_02830 1.5e-110 ykoI S Peptidase propeptide and YPEB domain
KMKKNLJM_02831 6.3e-85 ykoJ S Peptidase propeptide and YPEB domain
KMKKNLJM_02834 2.2e-222 mgtE P Acts as a magnesium transporter
KMKKNLJM_02835 1.4e-53 tnrA K transcriptional
KMKKNLJM_02836 5.9e-18
KMKKNLJM_02837 6.9e-26 ykoL
KMKKNLJM_02838 1.3e-81 mhqR K transcriptional
KMKKNLJM_02839 5e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KMKKNLJM_02840 2.7e-97 ykoP G polysaccharide deacetylase
KMKKNLJM_02841 6e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KMKKNLJM_02842 0.0 ykoS
KMKKNLJM_02843 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMKKNLJM_02844 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KMKKNLJM_02845 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KMKKNLJM_02846 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KMKKNLJM_02847 3.5e-109 ykoX S membrane-associated protein
KMKKNLJM_02848 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KMKKNLJM_02849 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_02850 3.1e-108 rsgI S Anti-sigma factor N-terminus
KMKKNLJM_02851 1.9e-26 sspD S small acid-soluble spore protein
KMKKNLJM_02852 5.6e-124 ykrK S Domain of unknown function (DUF1836)
KMKKNLJM_02853 3.5e-155 htpX O Belongs to the peptidase M48B family
KMKKNLJM_02854 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KMKKNLJM_02855 1.2e-10 ydfR S Protein of unknown function (DUF421)
KMKKNLJM_02856 4.1e-18 ykzE
KMKKNLJM_02857 2.7e-188 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KMKKNLJM_02858 0.0 kinE 2.7.13.3 T Histidine kinase
KMKKNLJM_02859 1.2e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMKKNLJM_02861 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KMKKNLJM_02862 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KMKKNLJM_02863 8.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KMKKNLJM_02864 3.1e-231 mtnE 2.6.1.83 E Aminotransferase
KMKKNLJM_02865 3.2e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KMKKNLJM_02866 8.3e-136 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KMKKNLJM_02867 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KMKKNLJM_02868 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KMKKNLJM_02869 2.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
KMKKNLJM_02870 7.5e-10 S Spo0E like sporulation regulatory protein
KMKKNLJM_02871 1.7e-62 eag
KMKKNLJM_02872 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMKKNLJM_02873 1.3e-75 ykvE K transcriptional
KMKKNLJM_02874 2.5e-125 motB N Flagellar motor protein
KMKKNLJM_02875 1e-137 motA N flagellar motor
KMKKNLJM_02876 0.0 clpE O Belongs to the ClpA ClpB family
KMKKNLJM_02877 3.3e-181 ykvI S membrane
KMKKNLJM_02878 2.1e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KMKKNLJM_02879 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KMKKNLJM_02880 4.9e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KMKKNLJM_02881 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KMKKNLJM_02882 3.8e-60 ykvN K HxlR-like helix-turn-helix
KMKKNLJM_02883 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_02884 1.2e-213 ykvP 3.5.1.28 M Glycosyl transferases group 1
KMKKNLJM_02885 3.5e-35 3.5.1.104 M LysM domain
KMKKNLJM_02886 5.3e-162 G Glycosyl hydrolases family 18
KMKKNLJM_02887 5.6e-46 ykvR S Protein of unknown function (DUF3219)
KMKKNLJM_02888 6e-25 ykvS S protein conserved in bacteria
KMKKNLJM_02889 2.8e-28
KMKKNLJM_02890 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
KMKKNLJM_02891 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_02892 4.9e-90 stoA CO thiol-disulfide
KMKKNLJM_02893 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KMKKNLJM_02894 2.3e-09
KMKKNLJM_02895 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KMKKNLJM_02896 4.9e-179 ykvZ 5.1.1.1 K Transcriptional regulator
KMKKNLJM_02898 7.6e-128 glcT K antiterminator
KMKKNLJM_02899 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_02900 2.1e-39 ptsH G phosphocarrier protein HPr
KMKKNLJM_02901 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KMKKNLJM_02902 7.2e-39 splA S Transcriptional regulator
KMKKNLJM_02903 1.7e-201 splB 4.1.99.14 L Spore photoproduct lyase
KMKKNLJM_02904 2.7e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KMKKNLJM_02905 1.3e-255 mcpC NT chemotaxis protein
KMKKNLJM_02906 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KMKKNLJM_02907 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
KMKKNLJM_02908 1.8e-123 ykwD J protein with SCP PR1 domains
KMKKNLJM_02909 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KMKKNLJM_02910 0.0 pilS 2.7.13.3 T Histidine kinase
KMKKNLJM_02911 6.3e-221 patA 2.6.1.1 E Aminotransferase
KMKKNLJM_02912 2.2e-15
KMKKNLJM_02913 1.4e-167 cheV 2.7.13.3 T Chemotaxis protein CheV
KMKKNLJM_02914 4.9e-84 ykyB S YkyB-like protein
KMKKNLJM_02915 2.8e-238 ykuC EGP Major facilitator Superfamily
KMKKNLJM_02916 1.8e-87 ykuD S protein conserved in bacteria
KMKKNLJM_02917 4.7e-165 ykuE S Metallophosphoesterase
KMKKNLJM_02918 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_02919 5.2e-234 ykuI T Diguanylate phosphodiesterase
KMKKNLJM_02920 3.9e-37 ykuJ S protein conserved in bacteria
KMKKNLJM_02921 4.4e-94 ykuK S Ribonuclease H-like
KMKKNLJM_02922 3.9e-27 ykzF S Antirepressor AbbA
KMKKNLJM_02923 1.6e-76 ykuL S CBS domain
KMKKNLJM_02924 3.5e-168 ccpC K Transcriptional regulator
KMKKNLJM_02925 2.9e-84 fld C Flavodoxin domain
KMKKNLJM_02926 8.8e-175 ykuO
KMKKNLJM_02927 4.3e-77 fld C Flavodoxin
KMKKNLJM_02928 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KMKKNLJM_02929 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KMKKNLJM_02930 9e-37 ykuS S Belongs to the UPF0180 family
KMKKNLJM_02931 8.8e-142 ykuT M Mechanosensitive ion channel
KMKKNLJM_02932 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KMKKNLJM_02933 1.4e-80 ykuV CO thiol-disulfide
KMKKNLJM_02934 5.8e-95 rok K Repressor of ComK
KMKKNLJM_02935 4.2e-146 yknT
KMKKNLJM_02936 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KMKKNLJM_02937 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KMKKNLJM_02938 1.9e-242 moeA 2.10.1.1 H molybdopterin
KMKKNLJM_02939 1.4e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KMKKNLJM_02940 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KMKKNLJM_02941 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KMKKNLJM_02942 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMKKNLJM_02943 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMKKNLJM_02944 3.6e-115 yknW S Yip1 domain
KMKKNLJM_02945 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KMKKNLJM_02946 3.6e-123 macB V ABC transporter, ATP-binding protein
KMKKNLJM_02947 4.7e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KMKKNLJM_02948 3.1e-136 fruR K Transcriptional regulator
KMKKNLJM_02949 5.3e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KMKKNLJM_02950 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KMKKNLJM_02951 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KMKKNLJM_02952 8.1e-39 ykoA
KMKKNLJM_02953 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMKKNLJM_02954 2.6e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMKKNLJM_02955 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KMKKNLJM_02956 1.1e-12 S Uncharacterized protein YkpC
KMKKNLJM_02957 1.7e-182 mreB D Rod-share determining protein MreBH
KMKKNLJM_02958 1.5e-43 abrB K of stationary sporulation gene expression
KMKKNLJM_02959 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KMKKNLJM_02960 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KMKKNLJM_02961 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KMKKNLJM_02962 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KMKKNLJM_02963 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMKKNLJM_02964 1.4e-30 ykzG S Belongs to the UPF0356 family
KMKKNLJM_02965 5.5e-147 ykrA S hydrolases of the HAD superfamily
KMKKNLJM_02966 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMKKNLJM_02968 1e-114 recN L Putative cell-wall binding lipoprotein
KMKKNLJM_02969 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMKKNLJM_02970 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMKKNLJM_02971 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMKKNLJM_02972 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMKKNLJM_02973 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KMKKNLJM_02974 4.5e-277 speA 4.1.1.19 E Arginine
KMKKNLJM_02975 1.6e-42 yktA S Belongs to the UPF0223 family
KMKKNLJM_02976 1.3e-116 yktB S Belongs to the UPF0637 family
KMKKNLJM_02977 7.1e-26 ykzI
KMKKNLJM_02978 1.8e-150 suhB 3.1.3.25 G Inositol monophosphatase
KMKKNLJM_02979 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KMKKNLJM_02980 7.1e-172 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KMKKNLJM_02981 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KMKKNLJM_02982 0.0 ylaA
KMKKNLJM_02983 3e-41 ylaB
KMKKNLJM_02984 1.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_02985 9.1e-12 sigC S Putative zinc-finger
KMKKNLJM_02986 5.9e-37 ylaE
KMKKNLJM_02987 8.2e-22 S Family of unknown function (DUF5325)
KMKKNLJM_02988 0.0 typA T GTP-binding protein TypA
KMKKNLJM_02989 4.2e-47 ylaH S YlaH-like protein
KMKKNLJM_02990 2.5e-32 ylaI S protein conserved in bacteria
KMKKNLJM_02991 2.3e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KMKKNLJM_02992 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KMKKNLJM_02993 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KMKKNLJM_02994 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KMKKNLJM_02995 8.7e-44 ylaN S Belongs to the UPF0358 family
KMKKNLJM_02996 7.2e-212 ftsW D Belongs to the SEDS family
KMKKNLJM_02997 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KMKKNLJM_02998 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KMKKNLJM_02999 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KMKKNLJM_03000 5.2e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KMKKNLJM_03001 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KMKKNLJM_03002 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KMKKNLJM_03003 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KMKKNLJM_03004 4.4e-166 ctaG S cytochrome c oxidase
KMKKNLJM_03005 2e-61 ylbA S YugN-like family
KMKKNLJM_03006 2.6e-74 ylbB T COG0517 FOG CBS domain
KMKKNLJM_03007 9.6e-200 ylbC S protein with SCP PR1 domains
KMKKNLJM_03008 3.4e-62 ylbD S Putative coat protein
KMKKNLJM_03009 1.5e-36 ylbE S YlbE-like protein
KMKKNLJM_03010 1.8e-75 ylbF S Belongs to the UPF0342 family
KMKKNLJM_03011 7.5e-39 ylbG S UPF0298 protein
KMKKNLJM_03012 1.2e-97 rsmD 2.1.1.171 L Methyltransferase
KMKKNLJM_03013 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KMKKNLJM_03014 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
KMKKNLJM_03015 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KMKKNLJM_03016 5.7e-186 ylbL T Belongs to the peptidase S16 family
KMKKNLJM_03017 6.6e-229 ylbM S Belongs to the UPF0348 family
KMKKNLJM_03019 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KMKKNLJM_03020 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KMKKNLJM_03021 2.2e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KMKKNLJM_03022 1.5e-88 ylbP K n-acetyltransferase
KMKKNLJM_03023 8.9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KMKKNLJM_03024 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KMKKNLJM_03025 2.9e-78 mraZ K Belongs to the MraZ family
KMKKNLJM_03026 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KMKKNLJM_03027 3.7e-44 ftsL D Essential cell division protein
KMKKNLJM_03028 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KMKKNLJM_03029 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KMKKNLJM_03030 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KMKKNLJM_03031 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KMKKNLJM_03032 4.5e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KMKKNLJM_03033 5.7e-186 spoVE D Belongs to the SEDS family
KMKKNLJM_03034 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KMKKNLJM_03035 5.3e-167 murB 1.3.1.98 M cell wall formation
KMKKNLJM_03036 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KMKKNLJM_03037 4.1e-103 ylxW S protein conserved in bacteria
KMKKNLJM_03038 1e-102 ylxX S protein conserved in bacteria
KMKKNLJM_03039 6.2e-58 sbp S small basic protein
KMKKNLJM_03040 1.2e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KMKKNLJM_03041 2.6e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KMKKNLJM_03042 0.0 bpr O COG1404 Subtilisin-like serine proteases
KMKKNLJM_03043 4.1e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KMKKNLJM_03044 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_03045 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_03046 2.4e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KMKKNLJM_03047 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
KMKKNLJM_03048 2.4e-37 ylmC S sporulation protein
KMKKNLJM_03049 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KMKKNLJM_03050 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KMKKNLJM_03051 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KMKKNLJM_03052 1.6e-39 yggT S membrane
KMKKNLJM_03053 2e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KMKKNLJM_03054 2.6e-67 divIVA D Cell division initiation protein
KMKKNLJM_03055 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KMKKNLJM_03056 1.3e-63 dksA T COG1734 DnaK suppressor protein
KMKKNLJM_03057 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KMKKNLJM_03058 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KMKKNLJM_03059 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KMKKNLJM_03060 2.6e-231 pyrP F Xanthine uracil
KMKKNLJM_03061 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KMKKNLJM_03062 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KMKKNLJM_03063 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KMKKNLJM_03064 0.0 carB 6.3.5.5 F Belongs to the CarB family
KMKKNLJM_03065 1.3e-142 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KMKKNLJM_03066 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KMKKNLJM_03067 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KMKKNLJM_03068 5.6e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KMKKNLJM_03070 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KMKKNLJM_03071 4.1e-179 cysP P phosphate transporter
KMKKNLJM_03072 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KMKKNLJM_03073 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KMKKNLJM_03074 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KMKKNLJM_03075 7.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KMKKNLJM_03076 8.2e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KMKKNLJM_03077 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KMKKNLJM_03078 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KMKKNLJM_03079 2.4e-156 yloC S stress-induced protein
KMKKNLJM_03080 1.5e-40 ylzA S Belongs to the UPF0296 family
KMKKNLJM_03081 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KMKKNLJM_03082 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KMKKNLJM_03083 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KMKKNLJM_03084 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMKKNLJM_03085 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KMKKNLJM_03086 8e-174 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KMKKNLJM_03087 6.6e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KMKKNLJM_03088 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KMKKNLJM_03089 1.6e-140 stp 3.1.3.16 T phosphatase
KMKKNLJM_03090 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KMKKNLJM_03091 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KMKKNLJM_03092 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KMKKNLJM_03093 1e-119 thiN 2.7.6.2 H thiamine pyrophosphokinase
KMKKNLJM_03094 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KMKKNLJM_03095 5.5e-59 asp S protein conserved in bacteria
KMKKNLJM_03096 1.6e-299 yloV S kinase related to dihydroxyacetone kinase
KMKKNLJM_03097 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KMKKNLJM_03098 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KMKKNLJM_03099 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KMKKNLJM_03100 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KMKKNLJM_03101 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KMKKNLJM_03102 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMKKNLJM_03103 5.1e-128 IQ reductase
KMKKNLJM_03104 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KMKKNLJM_03105 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KMKKNLJM_03106 0.0 smc D Required for chromosome condensation and partitioning
KMKKNLJM_03107 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KMKKNLJM_03108 2.9e-87
KMKKNLJM_03109 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KMKKNLJM_03110 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KMKKNLJM_03111 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KMKKNLJM_03112 4.5e-36 ylqC S Belongs to the UPF0109 family
KMKKNLJM_03113 1.4e-60 ylqD S YlqD protein
KMKKNLJM_03114 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KMKKNLJM_03115 4.6e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KMKKNLJM_03116 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KMKKNLJM_03117 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KMKKNLJM_03118 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KMKKNLJM_03119 1.1e-285 ylqG
KMKKNLJM_03120 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KMKKNLJM_03121 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KMKKNLJM_03122 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KMKKNLJM_03123 4e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KMKKNLJM_03124 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMKKNLJM_03125 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KMKKNLJM_03126 5.7e-169 xerC L tyrosine recombinase XerC
KMKKNLJM_03127 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KMKKNLJM_03128 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KMKKNLJM_03129 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KMKKNLJM_03130 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KMKKNLJM_03131 2e-74 flgC N Belongs to the flagella basal body rod proteins family
KMKKNLJM_03132 1.9e-31 fliE N Flagellar hook-basal body
KMKKNLJM_03133 3.5e-254 fliF N The M ring may be actively involved in energy transduction
KMKKNLJM_03134 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMKKNLJM_03135 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KMKKNLJM_03136 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KMKKNLJM_03137 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KMKKNLJM_03138 2.2e-36 ylxF S MgtE intracellular N domain
KMKKNLJM_03139 4.9e-215 fliK N Flagellar hook-length control protein
KMKKNLJM_03140 2.3e-72 flgD N Flagellar basal body rod modification protein
KMKKNLJM_03141 1.9e-136 flgG N Flagellar basal body rod
KMKKNLJM_03142 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KMKKNLJM_03143 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KMKKNLJM_03144 1e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KMKKNLJM_03145 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KMKKNLJM_03146 1.9e-94 fliZ N Flagellar biosynthesis protein, FliO
KMKKNLJM_03147 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KMKKNLJM_03148 2.2e-36 fliQ N Role in flagellar biosynthesis
KMKKNLJM_03149 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KMKKNLJM_03150 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMKKNLJM_03151 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KMKKNLJM_03152 5.7e-200 flhF N Flagellar biosynthesis regulator FlhF
KMKKNLJM_03153 1.7e-157 flhG D Belongs to the ParA family
KMKKNLJM_03154 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KMKKNLJM_03155 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KMKKNLJM_03156 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KMKKNLJM_03157 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KMKKNLJM_03158 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KMKKNLJM_03159 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_03160 5.3e-76 ylxL
KMKKNLJM_03161 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KMKKNLJM_03162 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KMKKNLJM_03163 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KMKKNLJM_03164 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KMKKNLJM_03165 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KMKKNLJM_03166 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KMKKNLJM_03167 2.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KMKKNLJM_03168 7.7e-233 rasP M zinc metalloprotease
KMKKNLJM_03169 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KMKKNLJM_03170 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMKKNLJM_03171 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KMKKNLJM_03172 1.1e-203 nusA K Participates in both transcription termination and antitermination
KMKKNLJM_03173 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KMKKNLJM_03174 3.1e-47 ylxQ J ribosomal protein
KMKKNLJM_03175 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KMKKNLJM_03176 3.9e-44 ylxP S protein conserved in bacteria
KMKKNLJM_03177 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KMKKNLJM_03178 5.6e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KMKKNLJM_03179 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KMKKNLJM_03180 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KMKKNLJM_03181 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KMKKNLJM_03182 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KMKKNLJM_03183 4.4e-233 pepR S Belongs to the peptidase M16 family
KMKKNLJM_03184 2.6e-42 ymxH S YlmC YmxH family
KMKKNLJM_03185 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KMKKNLJM_03186 4.8e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KMKKNLJM_03187 4.1e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KMKKNLJM_03188 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KMKKNLJM_03189 3.4e-155 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KMKKNLJM_03190 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KMKKNLJM_03191 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KMKKNLJM_03192 2.9e-31 S YlzJ-like protein
KMKKNLJM_03193 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KMKKNLJM_03194 1.4e-133 ymfC K Transcriptional regulator
KMKKNLJM_03195 3.8e-205 ymfD EGP Major facilitator Superfamily
KMKKNLJM_03196 2.7e-233 ymfF S Peptidase M16
KMKKNLJM_03197 2.1e-241 ymfH S zinc protease
KMKKNLJM_03198 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KMKKNLJM_03199 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KMKKNLJM_03200 2.7e-143 ymfK S Protein of unknown function (DUF3388)
KMKKNLJM_03201 1.9e-124 ymfM S protein conserved in bacteria
KMKKNLJM_03202 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMKKNLJM_03203 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KMKKNLJM_03204 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KMKKNLJM_03205 2.6e-214 pbpX V Beta-lactamase
KMKKNLJM_03206 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KMKKNLJM_03207 1.9e-152 ymdB S protein conserved in bacteria
KMKKNLJM_03208 1.2e-36 spoVS S Stage V sporulation protein S
KMKKNLJM_03209 3.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KMKKNLJM_03210 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KMKKNLJM_03211 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KMKKNLJM_03212 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KMKKNLJM_03213 2.2e-88 cotE S Spore coat protein
KMKKNLJM_03214 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KMKKNLJM_03215 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KMKKNLJM_03216 4.1e-67 S Regulatory protein YrvL
KMKKNLJM_03218 5.1e-96 ymcC S Membrane
KMKKNLJM_03219 9.9e-109 pksA K Transcriptional regulator
KMKKNLJM_03220 4.7e-128 pksB 3.1.2.6 S Polyketide biosynthesis
KMKKNLJM_03221 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMKKNLJM_03222 6.6e-184 pksD Q Acyl transferase domain
KMKKNLJM_03223 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KMKKNLJM_03224 1.4e-37 acpK IQ Phosphopantetheine attachment site
KMKKNLJM_03225 2.8e-235 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KMKKNLJM_03226 1.5e-244 pksG 2.3.3.10 I synthase
KMKKNLJM_03227 2.7e-140 pksH 4.2.1.18 I enoyl-CoA hydratase
KMKKNLJM_03228 6.1e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KMKKNLJM_03229 0.0 rhiB IQ polyketide synthase
KMKKNLJM_03230 0.0 pfaA Q Polyketide synthase of type I
KMKKNLJM_03231 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KMKKNLJM_03232 0.0 dhbF IQ polyketide synthase
KMKKNLJM_03233 0.0 pks13 HQ Beta-ketoacyl synthase
KMKKNLJM_03234 1.8e-231 cypA C Cytochrome P450
KMKKNLJM_03235 2e-61 ymzB
KMKKNLJM_03236 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
KMKKNLJM_03237 5e-251 aprX O Belongs to the peptidase S8 family
KMKKNLJM_03238 1.9e-07 K Transcriptional regulator
KMKKNLJM_03239 2.1e-126 ymaC S Replication protein
KMKKNLJM_03240 1.3e-78 ymaD O redox protein, regulator of disulfide bond formation
KMKKNLJM_03241 1.4e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KMKKNLJM_03242 5.4e-50 ebrA P Small Multidrug Resistance protein
KMKKNLJM_03244 1e-45 ymaF S YmaF family
KMKKNLJM_03245 1.3e-173 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KMKKNLJM_03246 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KMKKNLJM_03247 9.7e-16
KMKKNLJM_03248 4.5e-22 ymzA
KMKKNLJM_03249 7.4e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KMKKNLJM_03250 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMKKNLJM_03251 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KMKKNLJM_03252 2e-109 ymaB
KMKKNLJM_03253 1.4e-115 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMKKNLJM_03254 1.7e-176 spoVK O stage V sporulation protein K
KMKKNLJM_03255 5.1e-229 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KMKKNLJM_03256 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KMKKNLJM_03257 1.1e-68 glnR K transcriptional
KMKKNLJM_03258 7e-261 glnA 6.3.1.2 E glutamine synthetase
KMKKNLJM_03259 1.1e-64
KMKKNLJM_03260 1.5e-15
KMKKNLJM_03262 7.5e-59
KMKKNLJM_03263 3e-08 KLT serine threonine protein kinase
KMKKNLJM_03267 1.7e-77 L phage terminase small subunit
KMKKNLJM_03268 4.2e-17 S Terminase
KMKKNLJM_03271 3.8e-10
KMKKNLJM_03272 4.6e-31
KMKKNLJM_03273 3.2e-37
KMKKNLJM_03274 8.9e-90 G SMI1-KNR4 cell-wall
KMKKNLJM_03275 9.6e-141 ynaC
KMKKNLJM_03276 8.3e-12 S Protein of unknown function (DUF1433)
KMKKNLJM_03277 2.5e-97 ynaD J Acetyltransferase (GNAT) domain
KMKKNLJM_03278 3.1e-121 ynaE S Domain of unknown function (DUF3885)
KMKKNLJM_03281 5.5e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KMKKNLJM_03282 2.3e-254 xynT G MFS/sugar transport protein
KMKKNLJM_03283 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KMKKNLJM_03284 2.3e-212 xylR GK ROK family
KMKKNLJM_03285 1.6e-260 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KMKKNLJM_03286 1.8e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KMKKNLJM_03287 1.2e-112 yokF 3.1.31.1 L RNA catabolic process
KMKKNLJM_03288 4.7e-255 iolT EGP Major facilitator Superfamily
KMKKNLJM_03289 3.8e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMKKNLJM_03291 5e-81 yncE S Protein of unknown function (DUF2691)
KMKKNLJM_03292 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KMKKNLJM_03293 5.2e-15
KMKKNLJM_03296 8.6e-164 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KMKKNLJM_03297 1.2e-127 S Domain of unknown function, YrpD
KMKKNLJM_03300 7.9e-25 tatA U protein secretion
KMKKNLJM_03301 1.8e-71
KMKKNLJM_03302 1.3e-78 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KMKKNLJM_03305 3.2e-281 gerAA EG Spore germination protein
KMKKNLJM_03306 2.5e-195 gerAB U Spore germination
KMKKNLJM_03307 6.7e-210 gerLC S Spore germination protein
KMKKNLJM_03308 1.8e-150 yndG S DoxX-like family
KMKKNLJM_03309 3.2e-115 yndH S Domain of unknown function (DUF4166)
KMKKNLJM_03310 3e-306 yndJ S YndJ-like protein
KMKKNLJM_03312 2e-135 yndL S Replication protein
KMKKNLJM_03313 5.8e-74 yndM S Protein of unknown function (DUF2512)
KMKKNLJM_03314 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KMKKNLJM_03316 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KMKKNLJM_03317 7.6e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KMKKNLJM_03318 3.6e-109 yneB L resolvase
KMKKNLJM_03319 4.8e-32 ynzC S UPF0291 protein
KMKKNLJM_03320 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KMKKNLJM_03321 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KMKKNLJM_03322 1.8e-28 yneF S UPF0154 protein
KMKKNLJM_03323 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KMKKNLJM_03324 6e-126 ccdA O cytochrome c biogenesis protein
KMKKNLJM_03325 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KMKKNLJM_03326 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KMKKNLJM_03327 4.2e-74 yneK S Protein of unknown function (DUF2621)
KMKKNLJM_03328 1.7e-63 hspX O Spore coat protein
KMKKNLJM_03329 3.9e-19 sspP S Belongs to the SspP family
KMKKNLJM_03330 2.2e-14 sspO S Belongs to the SspO family
KMKKNLJM_03331 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KMKKNLJM_03332 1.1e-89 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KMKKNLJM_03334 3.1e-08 sspN S Small acid-soluble spore protein N family
KMKKNLJM_03335 3.9e-35 tlp S Belongs to the Tlp family
KMKKNLJM_03336 1.2e-73 yneP S Thioesterase-like superfamily
KMKKNLJM_03337 1.3e-53 yneQ
KMKKNLJM_03338 4.1e-49 yneR S Belongs to the HesB IscA family
KMKKNLJM_03339 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KMKKNLJM_03340 6.6e-69 yccU S CoA-binding protein
KMKKNLJM_03341 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMKKNLJM_03342 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KMKKNLJM_03343 2.3e-12
KMKKNLJM_03344 1.3e-57 ynfC
KMKKNLJM_03345 1.2e-250 agcS E Sodium alanine symporter
KMKKNLJM_03346 4.9e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KMKKNLJM_03348 2.5e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KMKKNLJM_03349 1.7e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KMKKNLJM_03350 8.5e-78 yngA S membrane
KMKKNLJM_03351 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KMKKNLJM_03352 5.5e-104 yngC S membrane-associated protein
KMKKNLJM_03353 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
KMKKNLJM_03354 5.9e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KMKKNLJM_03355 1.3e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KMKKNLJM_03356 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KMKKNLJM_03357 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KMKKNLJM_03358 1.6e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KMKKNLJM_03359 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KMKKNLJM_03360 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KMKKNLJM_03361 9e-26 S Family of unknown function (DUF5367)
KMKKNLJM_03363 7.7e-304 yngK T Glycosyl hydrolase-like 10
KMKKNLJM_03364 2.8e-64 yngL S Protein of unknown function (DUF1360)
KMKKNLJM_03365 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KMKKNLJM_03366 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_03367 2e-08
KMKKNLJM_03374 2e-08
KMKKNLJM_03376 7.8e-08
KMKKNLJM_03378 4.9e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KMKKNLJM_03379 5.2e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KMKKNLJM_03380 4.5e-126 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KMKKNLJM_03381 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KMKKNLJM_03382 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KMKKNLJM_03383 0.0 ydiF S ABC transporter
KMKKNLJM_03384 7.2e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KMKKNLJM_03385 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KMKKNLJM_03386 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMKKNLJM_03387 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMKKNLJM_03388 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KMKKNLJM_03389 7.9e-129 ydiL S CAAX protease self-immunity
KMKKNLJM_03390 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KMKKNLJM_03391 2.8e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KMKKNLJM_03392 2.4e-24 S SMI1-KNR4 cell-wall
KMKKNLJM_03393 2.9e-17 3.1.21.3 V Type I restriction modification DNA specificity domain
KMKKNLJM_03398 9.3e-61 V abc transporter atp-binding protein
KMKKNLJM_03399 0.0 K NB-ARC domain
KMKKNLJM_03400 2e-197 gutB 1.1.1.14 E Dehydrogenase
KMKKNLJM_03401 3.7e-252 gutA G MFS/sugar transport protein
KMKKNLJM_03402 1.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KMKKNLJM_03403 1.9e-113 pspA KT Phage shock protein A
KMKKNLJM_03404 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KMKKNLJM_03405 1.9e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KMKKNLJM_03406 5.9e-148 ydjI S virion core protein (lumpy skin disease virus)
KMKKNLJM_03407 4e-195 S Ion transport 2 domain protein
KMKKNLJM_03408 1.7e-257 iolT EGP Major facilitator Superfamily
KMKKNLJM_03409 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KMKKNLJM_03410 4.5e-64 ydjM M Lytic transglycolase
KMKKNLJM_03411 3.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
KMKKNLJM_03413 1.2e-34 ydjO S Cold-inducible protein YdjO
KMKKNLJM_03414 3.1e-158 ydjP I Alpha/beta hydrolase family
KMKKNLJM_03415 1.9e-178 yeaA S Protein of unknown function (DUF4003)
KMKKNLJM_03416 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KMKKNLJM_03417 9.7e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_03418 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMKKNLJM_03419 4.7e-174 yeaC S COG0714 MoxR-like ATPases
KMKKNLJM_03420 7.1e-220 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KMKKNLJM_03421 0.0 yebA E COG1305 Transglutaminase-like enzymes
KMKKNLJM_03422 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KMKKNLJM_03423 1e-211 pbuG S permease
KMKKNLJM_03424 8.9e-118 yebC M Membrane
KMKKNLJM_03426 8.9e-93 yebE S UPF0316 protein
KMKKNLJM_03427 8e-28 yebG S NETI protein
KMKKNLJM_03428 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KMKKNLJM_03429 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KMKKNLJM_03430 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KMKKNLJM_03431 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KMKKNLJM_03432 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMKKNLJM_03433 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMKKNLJM_03434 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KMKKNLJM_03435 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KMKKNLJM_03436 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KMKKNLJM_03437 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KMKKNLJM_03438 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KMKKNLJM_03439 1.3e-232 purD 6.3.4.13 F Belongs to the GARS family
KMKKNLJM_03440 3.3e-71 K helix_turn_helix ASNC type
KMKKNLJM_03441 4.1e-226 yjeH E Amino acid permease
KMKKNLJM_03442 6e-27 S Protein of unknown function (DUF2892)
KMKKNLJM_03443 0.0 yerA 3.5.4.2 F adenine deaminase
KMKKNLJM_03444 5.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
KMKKNLJM_03445 4.8e-51 yerC S protein conserved in bacteria
KMKKNLJM_03446 5.7e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KMKKNLJM_03448 1.9e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KMKKNLJM_03449 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KMKKNLJM_03450 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KMKKNLJM_03451 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KMKKNLJM_03452 1e-195 yerI S homoserine kinase type II (protein kinase fold)
KMKKNLJM_03453 1.6e-123 sapB S MgtC SapB transporter
KMKKNLJM_03454 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMKKNLJM_03455 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMKKNLJM_03456 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KMKKNLJM_03457 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KMKKNLJM_03458 8.7e-148 yerO K Transcriptional regulator
KMKKNLJM_03459 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KMKKNLJM_03460 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KMKKNLJM_03461 1.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMKKNLJM_03462 3.6e-10
KMKKNLJM_03463 7.8e-100
KMKKNLJM_03465 5.3e-100 S response regulator aspartate phosphatase
KMKKNLJM_03467 3.5e-27
KMKKNLJM_03468 1.2e-167 yobL S Bacterial EndoU nuclease
KMKKNLJM_03469 1.8e-176 3.4.24.40 CO amine dehydrogenase activity
KMKKNLJM_03470 5.2e-39
KMKKNLJM_03471 2.2e-210 S Tetratricopeptide repeat
KMKKNLJM_03473 9.4e-127 yeeN K transcriptional regulatory protein
KMKKNLJM_03475 2.7e-100 dhaR3 K Transcriptional regulator
KMKKNLJM_03476 1.8e-80 yesE S SnoaL-like domain
KMKKNLJM_03477 3.8e-143 yesF GM NAD(P)H-binding
KMKKNLJM_03478 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KMKKNLJM_03479 1.5e-45 cotJB S CotJB protein
KMKKNLJM_03480 5.2e-104 cotJC P Spore Coat
KMKKNLJM_03481 1.3e-101 yesJ K Acetyltransferase (GNAT) family
KMKKNLJM_03483 5.4e-102 yesL S Protein of unknown function, DUF624
KMKKNLJM_03484 0.0 yesM 2.7.13.3 T Histidine kinase
KMKKNLJM_03485 1.6e-202 yesN K helix_turn_helix, arabinose operon control protein
KMKKNLJM_03486 3.3e-247 yesO G Bacterial extracellular solute-binding protein
KMKKNLJM_03487 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KMKKNLJM_03488 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
KMKKNLJM_03489 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KMKKNLJM_03490 0.0 yesS K Transcriptional regulator
KMKKNLJM_03491 7.2e-132 E GDSL-like Lipase/Acylhydrolase
KMKKNLJM_03492 8.7e-127 yesU S Domain of unknown function (DUF1961)
KMKKNLJM_03493 1e-113 yesV S Protein of unknown function, DUF624
KMKKNLJM_03494 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KMKKNLJM_03495 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KMKKNLJM_03496 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
KMKKNLJM_03497 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KMKKNLJM_03498 0.0 yetA
KMKKNLJM_03499 6.9e-289 lplA G Bacterial extracellular solute-binding protein
KMKKNLJM_03500 1.9e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KMKKNLJM_03501 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KMKKNLJM_03502 3.2e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KMKKNLJM_03503 4e-122 yetF S membrane
KMKKNLJM_03504 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KMKKNLJM_03505 5.7e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KMKKNLJM_03506 6.4e-35
KMKKNLJM_03507 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KMKKNLJM_03508 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KMKKNLJM_03509 9.1e-105 yetJ S Belongs to the BI1 family
KMKKNLJM_03510 8.2e-27 yetM CH FAD binding domain
KMKKNLJM_03511 3.1e-198 yetN S Protein of unknown function (DUF3900)
KMKKNLJM_03512 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KMKKNLJM_03513 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMKKNLJM_03514 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KMKKNLJM_03515 1.9e-172 yfnG 4.2.1.45 M dehydratase
KMKKNLJM_03516 5.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
KMKKNLJM_03517 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KMKKNLJM_03518 3.9e-189 yfnD M Nucleotide-diphospho-sugar transferase
KMKKNLJM_03519 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
KMKKNLJM_03520 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KMKKNLJM_03521 1.4e-240 yfnA E amino acid
KMKKNLJM_03522 2.4e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMKKNLJM_03523 1.1e-113 yfmS NT chemotaxis protein
KMKKNLJM_03524 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMKKNLJM_03525 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
KMKKNLJM_03526 2.4e-69 yfmP K transcriptional
KMKKNLJM_03527 9.5e-209 yfmO EGP Major facilitator Superfamily
KMKKNLJM_03528 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KMKKNLJM_03529 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KMKKNLJM_03530 6.8e-75 yfmK 2.3.1.128 K acetyltransferase
KMKKNLJM_03531 6.7e-187 yfmJ S N-terminal domain of oxidoreductase
KMKKNLJM_03532 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KMKKNLJM_03533 3.6e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03534 6.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03535 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KMKKNLJM_03536 2.6e-24 S Protein of unknown function (DUF3212)
KMKKNLJM_03537 7.6e-58 yflT S Heat induced stress protein YflT
KMKKNLJM_03538 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KMKKNLJM_03539 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
KMKKNLJM_03540 4.1e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMKKNLJM_03541 2.4e-116 citT T response regulator
KMKKNLJM_03542 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
KMKKNLJM_03543 8.5e-227 citM C Citrate transporter
KMKKNLJM_03544 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KMKKNLJM_03545 7.4e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KMKKNLJM_03546 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KMKKNLJM_03547 1.9e-121 yflK S protein conserved in bacteria
KMKKNLJM_03548 4e-18 yflJ S Protein of unknown function (DUF2639)
KMKKNLJM_03549 4.1e-19 yflI
KMKKNLJM_03550 1.5e-49 yflH S Protein of unknown function (DUF3243)
KMKKNLJM_03551 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KMKKNLJM_03552 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KMKKNLJM_03553 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KMKKNLJM_03554 6e-67 yhdN S Domain of unknown function (DUF1992)
KMKKNLJM_03555 2.2e-252 agcS_1 E Sodium alanine symporter
KMKKNLJM_03556 2.2e-25 yfkQ EG Spore germination protein
KMKKNLJM_03557 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_03558 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KMKKNLJM_03559 1.8e-133 treR K transcriptional
KMKKNLJM_03560 1.1e-124 yfkO C nitroreductase
KMKKNLJM_03561 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KMKKNLJM_03562 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
KMKKNLJM_03563 1.3e-205 ydiM EGP Major facilitator Superfamily
KMKKNLJM_03564 1.3e-28 yfkK S Belongs to the UPF0435 family
KMKKNLJM_03565 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KMKKNLJM_03566 4.1e-50 yfkI S gas vesicle protein
KMKKNLJM_03567 1.3e-143 yihY S Belongs to the UPF0761 family
KMKKNLJM_03568 3.8e-218 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KMKKNLJM_03569 1e-182 cax P COG0387 Ca2 H antiporter
KMKKNLJM_03570 3.4e-146 yfkD S YfkD-like protein
KMKKNLJM_03571 6e-149 yfkC M Mechanosensitive ion channel
KMKKNLJM_03572 5.4e-222 yfkA S YfkB-like domain
KMKKNLJM_03573 1.1e-26 yfjT
KMKKNLJM_03574 1.7e-153 pdaA G deacetylase
KMKKNLJM_03575 4.7e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KMKKNLJM_03576 1.7e-184 corA P Mediates influx of magnesium ions
KMKKNLJM_03577 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMKKNLJM_03578 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KMKKNLJM_03579 6.3e-42 S YfzA-like protein
KMKKNLJM_03580 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMKKNLJM_03581 9.6e-85 yfjM S Psort location Cytoplasmic, score
KMKKNLJM_03582 1.7e-29 yfjL
KMKKNLJM_03583 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KMKKNLJM_03584 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KMKKNLJM_03585 1.9e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KMKKNLJM_03586 2.7e-255 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KMKKNLJM_03587 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KMKKNLJM_03588 1.2e-25 sspH S Belongs to the SspH family
KMKKNLJM_03589 4e-56 yfjF S UPF0060 membrane protein
KMKKNLJM_03590 1.1e-85 S Family of unknown function (DUF5381)
KMKKNLJM_03591 1.2e-124 yfjC
KMKKNLJM_03592 9.6e-172 yfjB
KMKKNLJM_03593 1.1e-44 yfjA S Belongs to the WXG100 family
KMKKNLJM_03594 4.9e-262 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KMKKNLJM_03595 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
KMKKNLJM_03596 2.3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_03597 0.0 yobO M COG5434 Endopolygalacturonase
KMKKNLJM_03598 8.4e-307 yfiB3 V ABC transporter
KMKKNLJM_03599 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KMKKNLJM_03600 6.4e-64 mhqP S DoxX
KMKKNLJM_03601 9.7e-163 yfiE 1.13.11.2 S glyoxalase
KMKKNLJM_03602 3.5e-166 K AraC-like ligand binding domain
KMKKNLJM_03603 5.4e-08 iolT EGP Major facilitator Superfamily
KMKKNLJM_03604 5.3e-178 G Xylose isomerase
KMKKNLJM_03605 2e-227 S Oxidoreductase
KMKKNLJM_03606 6.9e-191 yxjM T Histidine kinase
KMKKNLJM_03607 6e-112 KT LuxR family transcriptional regulator
KMKKNLJM_03608 3.2e-167 V ABC transporter, ATP-binding protein
KMKKNLJM_03609 2e-206 V ABC-2 family transporter protein
KMKKNLJM_03610 7.6e-203 V COG0842 ABC-type multidrug transport system, permease component
KMKKNLJM_03611 4.1e-98 padR K transcriptional
KMKKNLJM_03612 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMKKNLJM_03613 2.6e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KMKKNLJM_03614 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
KMKKNLJM_03615 5.3e-284 yfiU EGP Major facilitator Superfamily
KMKKNLJM_03616 1.4e-78 yfiV K transcriptional
KMKKNLJM_03617 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KMKKNLJM_03618 5.7e-175 yfiY P ABC transporter substrate-binding protein
KMKKNLJM_03619 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03620 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03621 1.5e-166 yfhB 5.3.3.17 S PhzF family
KMKKNLJM_03622 3.9e-107 yfhC C nitroreductase
KMKKNLJM_03623 2.1e-25 yfhD S YfhD-like protein
KMKKNLJM_03625 4.3e-169 yfhF S nucleoside-diphosphate sugar epimerase
KMKKNLJM_03626 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KMKKNLJM_03627 1.7e-51 yfhH S Protein of unknown function (DUF1811)
KMKKNLJM_03629 5.6e-209 yfhI EGP Major facilitator Superfamily
KMKKNLJM_03630 6.2e-20 sspK S reproduction
KMKKNLJM_03631 1.3e-44 yfhJ S WVELL protein
KMKKNLJM_03632 2.1e-88 batE T Bacterial SH3 domain homologues
KMKKNLJM_03633 3.9e-50 yfhL S SdpI/YhfL protein family
KMKKNLJM_03634 1.3e-170 yfhM S Alpha beta hydrolase
KMKKNLJM_03635 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KMKKNLJM_03636 0.0 yfhO S Bacterial membrane protein YfhO
KMKKNLJM_03637 1.2e-185 yfhP S membrane-bound metal-dependent
KMKKNLJM_03638 3.3e-210 mutY L A G-specific
KMKKNLJM_03639 6.9e-36 yfhS
KMKKNLJM_03640 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_03641 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KMKKNLJM_03642 1.5e-37 ygaB S YgaB-like protein
KMKKNLJM_03643 1.3e-104 ygaC J Belongs to the UPF0374 family
KMKKNLJM_03644 5.3e-301 ygaD V ABC transporter
KMKKNLJM_03645 3.3e-179 ygaE S Membrane
KMKKNLJM_03646 7.6e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KMKKNLJM_03647 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
KMKKNLJM_03648 4e-80 perR P Belongs to the Fur family
KMKKNLJM_03649 9.5e-56 ygzB S UPF0295 protein
KMKKNLJM_03650 6.7e-167 ygxA S Nucleotidyltransferase-like
KMKKNLJM_03653 4.6e-157 ydhU P Catalase
KMKKNLJM_03654 1.7e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KMKKNLJM_03655 1.7e-184 manA 5.3.1.8 G mannose-6-phosphate isomerase
KMKKNLJM_03656 2.6e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KMKKNLJM_03657 2.1e-131 ydhQ K UTRA
KMKKNLJM_03658 5.2e-283 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMKKNLJM_03659 2.2e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KMKKNLJM_03660 1.3e-49 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMKKNLJM_03661 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KMKKNLJM_03662 1e-199 pbuE EGP Major facilitator Superfamily
KMKKNLJM_03663 2.5e-98 ydhK M Protein of unknown function (DUF1541)
KMKKNLJM_03664 4e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KMKKNLJM_03665 2.5e-83 K Acetyltransferase (GNAT) domain
KMKKNLJM_03667 4.3e-67 frataxin S Domain of unknown function (DU1801)
KMKKNLJM_03668 1.2e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KMKKNLJM_03669 2.5e-124
KMKKNLJM_03670 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KMKKNLJM_03671 1.6e-243 ydhD M Glycosyl hydrolase
KMKKNLJM_03672 6.5e-122 ydhC K FCD
KMKKNLJM_03673 2.7e-121 ydhB S membrane transporter protein
KMKKNLJM_03674 4.1e-207 tcaB EGP Major facilitator Superfamily
KMKKNLJM_03675 2.4e-69 ydgJ K Winged helix DNA-binding domain
KMKKNLJM_03676 4e-113 drgA C nitroreductase
KMKKNLJM_03677 0.0 ydgH S drug exporters of the RND superfamily
KMKKNLJM_03678 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KMKKNLJM_03679 1.6e-88 dinB S DinB family
KMKKNLJM_03680 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_03681 8.6e-301 expZ S ABC transporter
KMKKNLJM_03682 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
KMKKNLJM_03683 8.1e-52 S DoxX-like family
KMKKNLJM_03684 4.2e-96 K Bacterial regulatory proteins, tetR family
KMKKNLJM_03685 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KMKKNLJM_03686 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
KMKKNLJM_03687 1.1e-74 cotP O Belongs to the small heat shock protein (HSP20) family
KMKKNLJM_03688 7.6e-121 ydfS S Protein of unknown function (DUF421)
KMKKNLJM_03689 2.2e-100 ydfR S Protein of unknown function (DUF421)
KMKKNLJM_03691 6.3e-29
KMKKNLJM_03692 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KMKKNLJM_03693 1.7e-54 traF CO Thioredoxin
KMKKNLJM_03694 8.8e-63 mhqP S DoxX
KMKKNLJM_03695 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KMKKNLJM_03696 9.6e-112 ydfN C nitroreductase
KMKKNLJM_03697 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMKKNLJM_03698 6e-146 K Bacterial transcription activator, effector binding domain
KMKKNLJM_03699 2.9e-117 S Protein of unknown function (DUF554)
KMKKNLJM_03700 1.1e-172 S Alpha/beta hydrolase family
KMKKNLJM_03701 0.0 ydfJ S drug exporters of the RND superfamily
KMKKNLJM_03702 5.5e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KMKKNLJM_03703 2.6e-179 ydfH 2.7.13.3 T Histidine kinase
KMKKNLJM_03705 5e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KMKKNLJM_03706 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KMKKNLJM_03707 1.2e-114 ydfE S Flavin reductase like domain
KMKKNLJM_03708 1.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_03709 2.2e-149 ydfC EG EamA-like transporter family
KMKKNLJM_03710 3.1e-122 T Transcriptional regulatory protein, C terminal
KMKKNLJM_03711 2.9e-212 T GHKL domain
KMKKNLJM_03712 3.9e-159
KMKKNLJM_03713 7e-123 nodB1 G deacetylase
KMKKNLJM_03714 2.8e-149 lytR K Transcriptional regulator
KMKKNLJM_03715 1.2e-129 ydfB J GNAT acetyltransferase
KMKKNLJM_03716 1.3e-227 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KMKKNLJM_03717 2.8e-57 arsR K transcriptional
KMKKNLJM_03718 3.2e-104 ydeS K Transcriptional regulator
KMKKNLJM_03719 4.3e-193 ydeR EGP Major facilitator Superfamily
KMKKNLJM_03720 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KMKKNLJM_03721 7.2e-39 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KMKKNLJM_03722 1.5e-67 ydeP K Transcriptional regulator
KMKKNLJM_03723 3.9e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KMKKNLJM_03724 8.9e-56 K HxlR-like helix-turn-helix
KMKKNLJM_03725 2.6e-103 ydeN S Serine hydrolase
KMKKNLJM_03726 1.3e-72 maoC I N-terminal half of MaoC dehydratase
KMKKNLJM_03727 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_03728 1.8e-153 ydeK EG -transporter
KMKKNLJM_03729 2.6e-84 K Transcriptional regulator C-terminal region
KMKKNLJM_03730 4.9e-15 ptsH G PTS HPr component phosphorylation site
KMKKNLJM_03731 1.1e-31 S SNARE associated Golgi protein
KMKKNLJM_03732 9.1e-100
KMKKNLJM_03733 2.1e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KMKKNLJM_03734 1e-216 ydeG EGP Major facilitator superfamily
KMKKNLJM_03735 6.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_03736 5.8e-163 ydeE K AraC family transcriptional regulator
KMKKNLJM_03737 1e-168 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMKKNLJM_03738 1.7e-162 rhaS5 K AraC-like ligand binding domain
KMKKNLJM_03739 1.8e-143 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KMKKNLJM_03740 2.3e-78 carD K Transcription factor
KMKKNLJM_03741 8.7e-30 cspL K Cold shock
KMKKNLJM_03742 2.8e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KMKKNLJM_03743 9.6e-40
KMKKNLJM_03744 3.4e-33 K Helix-turn-helix XRE-family like proteins
KMKKNLJM_03745 1.8e-14 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KMKKNLJM_03746 5e-47 ydeH
KMKKNLJM_03747 6.9e-208 msbA2 3.6.3.44 V ABC transporter
KMKKNLJM_03748 4.4e-211 KLT Protein kinase domain
KMKKNLJM_03755 2.3e-157 KLT Protein kinase domain
KMKKNLJM_03766 8.9e-83 ydcK S Belongs to the SprT family
KMKKNLJM_03767 0.0 yhgF K COG2183 Transcriptional accessory protein
KMKKNLJM_03768 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KMKKNLJM_03769 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KMKKNLJM_03770 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KMKKNLJM_03771 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KMKKNLJM_03772 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KMKKNLJM_03773 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KMKKNLJM_03774 5.2e-57 rsbS T antagonist
KMKKNLJM_03775 1.3e-143 rsbR T Positive regulator of sigma-B
KMKKNLJM_03776 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KMKKNLJM_03777 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KMKKNLJM_03778 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KMKKNLJM_03779 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KMKKNLJM_03780 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KMKKNLJM_03781 5.8e-106 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KMKKNLJM_03782 5.1e-260 ydbT S Membrane
KMKKNLJM_03783 2.1e-82 ydbS S Bacterial PH domain
KMKKNLJM_03784 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KMKKNLJM_03785 6.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KMKKNLJM_03786 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KMKKNLJM_03787 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KMKKNLJM_03788 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KMKKNLJM_03789 2.2e-07 S Fur-regulated basic protein A
KMKKNLJM_03790 1.1e-18 S Fur-regulated basic protein B
KMKKNLJM_03791 8.3e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KMKKNLJM_03792 2.7e-52 ydbL
KMKKNLJM_03793 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KMKKNLJM_03794 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
KMKKNLJM_03795 4.4e-181 ydbI S AI-2E family transporter
KMKKNLJM_03796 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMKKNLJM_03797 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KMKKNLJM_03798 1.5e-294 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KMKKNLJM_03799 6.7e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KMKKNLJM_03800 7.9e-154 ydbD P Catalase
KMKKNLJM_03801 4.1e-62 ydbC S Domain of unknown function (DUF4937
KMKKNLJM_03802 8.9e-59 ydbB G Cupin domain
KMKKNLJM_03804 1.2e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KMKKNLJM_03805 1.6e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KMKKNLJM_03807 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KMKKNLJM_03808 2.1e-39
KMKKNLJM_03810 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KMKKNLJM_03811 2.1e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KMKKNLJM_03812 0.0 ydaO E amino acid
KMKKNLJM_03813 0.0 ydaN S Bacterial cellulose synthase subunit
KMKKNLJM_03814 4.5e-233 ydaM M Glycosyl transferase family group 2
KMKKNLJM_03815 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KMKKNLJM_03816 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
KMKKNLJM_03817 2.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KMKKNLJM_03818 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KMKKNLJM_03819 2.5e-74 lrpC K Transcriptional regulator
KMKKNLJM_03820 3.6e-45 ydzA EGP Major facilitator Superfamily
KMKKNLJM_03821 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KMKKNLJM_03822 6.8e-77 ydaG 1.4.3.5 S general stress protein
KMKKNLJM_03823 1.5e-100 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KMKKNLJM_03824 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KMKKNLJM_03825 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_03826 3.4e-98 ydaC Q Methyltransferase domain
KMKKNLJM_03827 2.3e-292 ydaB IQ acyl-CoA ligase
KMKKNLJM_03828 0.0 mtlR K transcriptional regulator, MtlR
KMKKNLJM_03829 8.1e-176 ydhF S Oxidoreductase
KMKKNLJM_03830 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KMKKNLJM_03831 8e-47 yczJ S biosynthesis
KMKKNLJM_03833 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
KMKKNLJM_03834 2.7e-132 kipR K Transcriptional regulator
KMKKNLJM_03835 1.1e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KMKKNLJM_03836 3e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KMKKNLJM_03837 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
KMKKNLJM_03838 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KMKKNLJM_03839 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
KMKKNLJM_03840 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KMKKNLJM_03842 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KMKKNLJM_03843 7e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KMKKNLJM_03844 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KMKKNLJM_03846 4.2e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KMKKNLJM_03847 1.3e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KMKKNLJM_03848 4.4e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KMKKNLJM_03849 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KMKKNLJM_03850 3.4e-53
KMKKNLJM_03851 7.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KMKKNLJM_03852 5.5e-308 ycnJ P protein, homolog of Cu resistance protein CopC
KMKKNLJM_03853 1.4e-99 ycnI S protein conserved in bacteria
KMKKNLJM_03854 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KMKKNLJM_03855 6.1e-149 glcU U Glucose uptake
KMKKNLJM_03856 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMKKNLJM_03857 4.8e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KMKKNLJM_03858 7.3e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KMKKNLJM_03859 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KMKKNLJM_03860 1.6e-45 ycnE S Monooxygenase
KMKKNLJM_03861 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KMKKNLJM_03862 6.5e-154 ycnC K Transcriptional regulator
KMKKNLJM_03863 1.2e-250 ycnB EGP Major facilitator Superfamily
KMKKNLJM_03864 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KMKKNLJM_03865 1.3e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KMKKNLJM_03866 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03867 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_03868 2.6e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
KMKKNLJM_03872 1.3e-77 S aspartate phosphatase
KMKKNLJM_03873 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KMKKNLJM_03874 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_03875 1.4e-193 yclI V ABC transporter (permease) YclI
KMKKNLJM_03876 7.3e-121 yclH P ABC transporter
KMKKNLJM_03877 3.8e-199 gerKB F Spore germination protein
KMKKNLJM_03878 6.3e-232 gerKC S spore germination
KMKKNLJM_03879 3.5e-278 gerKA EG Spore germination protein
KMKKNLJM_03881 9.1e-309 yclG M Pectate lyase superfamily protein
KMKKNLJM_03882 1.5e-267 dtpT E amino acid peptide transporter
KMKKNLJM_03883 7.8e-157 yclE 3.4.11.5 S Alpha beta hydrolase
KMKKNLJM_03884 2.5e-80 yclD
KMKKNLJM_03885 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
KMKKNLJM_03886 4.5e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KMKKNLJM_03887 1.4e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KMKKNLJM_03888 1.9e-161 bsdA K LysR substrate binding domain
KMKKNLJM_03889 9.8e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KMKKNLJM_03890 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KMKKNLJM_03891 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KMKKNLJM_03892 9.7e-115 yczE S membrane
KMKKNLJM_03893 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KMKKNLJM_03894 1.4e-248 ycxD K GntR family transcriptional regulator
KMKKNLJM_03895 6.9e-162 ycxC EG EamA-like transporter family
KMKKNLJM_03896 1.3e-88 S YcxB-like protein
KMKKNLJM_03897 2.6e-59 EGP Major Facilitator Superfamily
KMKKNLJM_03898 6.7e-137 EGP Major Facilitator Superfamily
KMKKNLJM_03899 1.7e-139 srfAD Q thioesterase
KMKKNLJM_03900 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KMKKNLJM_03901 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KMKKNLJM_03904 1.3e-63 hxlR K transcriptional
KMKKNLJM_03905 1.8e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KMKKNLJM_03906 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KMKKNLJM_03907 1.2e-183 tlpC 2.7.13.3 NT chemotaxis protein
KMKKNLJM_03908 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
KMKKNLJM_03909 1.1e-68 nin S Competence protein J (ComJ)
KMKKNLJM_03910 1.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KMKKNLJM_03911 7.8e-52 yckD S Protein of unknown function (DUF2680)
KMKKNLJM_03912 3.1e-75 yckC S membrane
KMKKNLJM_03914 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KMKKNLJM_03915 1.2e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
KMKKNLJM_03916 5e-226 yciC S GTPases (G3E family)
KMKKNLJM_03917 5.1e-107 yciB M ErfK YbiS YcfS YnhG
KMKKNLJM_03918 3.5e-171 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KMKKNLJM_03919 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
KMKKNLJM_03920 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KMKKNLJM_03921 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KMKKNLJM_03922 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KMKKNLJM_03923 1.3e-56 nirD 1.7.1.15 P Nitrite reductase
KMKKNLJM_03924 1e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KMKKNLJM_03925 2.1e-188 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KMKKNLJM_03926 1.4e-158 I alpha/beta hydrolase fold
KMKKNLJM_03927 4.5e-139 ycgR S permeases
KMKKNLJM_03928 2.2e-146 ycgQ S membrane
KMKKNLJM_03929 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KMKKNLJM_03930 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KMKKNLJM_03931 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KMKKNLJM_03932 5.1e-170 ycgM E Proline dehydrogenase
KMKKNLJM_03933 2.4e-144 ycgL S Predicted nucleotidyltransferase
KMKKNLJM_03934 2.1e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KMKKNLJM_03935 2.7e-177 oxyR3 K LysR substrate binding domain
KMKKNLJM_03936 2.4e-144 yafE Q ubiE/COQ5 methyltransferase family
KMKKNLJM_03937 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KMKKNLJM_03938 2.3e-61 tmrB S AAA domain
KMKKNLJM_03939 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KMKKNLJM_03940 2.4e-112 ycgI S Domain of unknown function (DUF1989)
KMKKNLJM_03941 6.2e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_03942 2.2e-150 yqcI S YqcI/YcgG family
KMKKNLJM_03943 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KMKKNLJM_03944 1.3e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
KMKKNLJM_03945 1.1e-262 mdr EGP Major facilitator Superfamily
KMKKNLJM_03946 6.5e-293 lctP C L-lactate permease
KMKKNLJM_03947 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KMKKNLJM_03948 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KMKKNLJM_03949 4.5e-80 ycgB
KMKKNLJM_03950 5.6e-256 ycgA S Membrane
KMKKNLJM_03951 1.5e-214 amhX S amidohydrolase
KMKKNLJM_03952 5.3e-164 opuAC E glycine betaine
KMKKNLJM_03953 1.3e-127 opuAB P glycine betaine
KMKKNLJM_03954 4.3e-228 proV 3.6.3.32 E glycine betaine
KMKKNLJM_03955 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KMKKNLJM_03956 1.2e-200 yceJ EGP Uncharacterised MFS-type transporter YbfB
KMKKNLJM_03957 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
KMKKNLJM_03958 2e-192 yceH P Belongs to the TelA family
KMKKNLJM_03959 0.0 yceG S Putative component of 'biosynthetic module'
KMKKNLJM_03960 6.3e-137 terC P Protein of unknown function (DUF475)
KMKKNLJM_03961 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KMKKNLJM_03962 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KMKKNLJM_03963 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KMKKNLJM_03964 4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KMKKNLJM_03965 1.9e-134 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KMKKNLJM_03966 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KMKKNLJM_03967 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KMKKNLJM_03968 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KMKKNLJM_03969 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
KMKKNLJM_03970 1.2e-173 S response regulator aspartate phosphatase
KMKKNLJM_03971 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
KMKKNLJM_03972 2.2e-255 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_03973 8e-271 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_03974 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KMKKNLJM_03975 3.9e-173 yccK C Aldo keto reductase
KMKKNLJM_03976 5.1e-199 natB CP ABC-2 family transporter protein
KMKKNLJM_03977 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KMKKNLJM_03978 1.2e-126 lytR_2 T LytTr DNA-binding domain
KMKKNLJM_03979 2e-153 2.7.13.3 T GHKL domain
KMKKNLJM_03980 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
KMKKNLJM_03981 2e-59 S RDD family
KMKKNLJM_03982 6.2e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KMKKNLJM_03983 1.3e-199 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KMKKNLJM_03984 1.6e-100 yxaF K Transcriptional regulator
KMKKNLJM_03985 7.6e-229 lmrB EGP the major facilitator superfamily
KMKKNLJM_03986 6e-205 ycbU E Selenocysteine lyase
KMKKNLJM_03987 1.7e-119 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KMKKNLJM_03988 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KMKKNLJM_03989 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KMKKNLJM_03990 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KMKKNLJM_03991 6.2e-134 ycbR T vWA found in TerF C terminus
KMKKNLJM_03992 2.2e-78 sleB 3.5.1.28 M Cell wall
KMKKNLJM_03993 4.1e-52 ycbP S Protein of unknown function (DUF2512)
KMKKNLJM_03994 3.3e-113 S ABC-2 family transporter protein
KMKKNLJM_03995 5.9e-166 ycbN V ABC transporter, ATP-binding protein
KMKKNLJM_03996 2.9e-168 T PhoQ Sensor
KMKKNLJM_03997 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KMKKNLJM_03998 6e-129 eamA1 EG spore germination
KMKKNLJM_03999 2.2e-27 eamA1 EG spore germination
KMKKNLJM_04000 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KMKKNLJM_04001 2.9e-173 ycbJ S Macrolide 2'-phosphotransferase
KMKKNLJM_04002 3.5e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
KMKKNLJM_04003 2.1e-123 ycbG K FCD
KMKKNLJM_04004 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KMKKNLJM_04005 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KMKKNLJM_04006 3.1e-273 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KMKKNLJM_04007 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KMKKNLJM_04008 9e-170 glnL T Regulator
KMKKNLJM_04009 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
KMKKNLJM_04010 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
KMKKNLJM_04011 4.8e-255 agcS E Sodium alanine symporter
KMKKNLJM_04012 2.4e-178 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KMKKNLJM_04013 8.2e-260 mmuP E amino acid
KMKKNLJM_04014 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KMKKNLJM_04016 4.9e-128 K UTRA
KMKKNLJM_04017 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KMKKNLJM_04018 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_04019 1.1e-215 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KMKKNLJM_04020 3.3e-191 yceA S Belongs to the UPF0176 family
KMKKNLJM_04021 2.1e-252 S Erythromycin esterase
KMKKNLJM_04022 4.6e-45 ybfN
KMKKNLJM_04023 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KMKKNLJM_04024 2.7e-85 ybfM S SNARE associated Golgi protein
KMKKNLJM_04025 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KMKKNLJM_04026 4.1e-164 S Alpha/beta hydrolase family
KMKKNLJM_04028 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KMKKNLJM_04029 2e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KMKKNLJM_04030 2e-144 msmR K AraC-like ligand binding domain
KMKKNLJM_04031 2.4e-159 ybfH EG EamA-like transporter family
KMKKNLJM_04032 0.0 ybfG M Domain of unknown function (DUF1906)
KMKKNLJM_04034 6e-222 ybfB G COG0477 Permeases of the major facilitator superfamily
KMKKNLJM_04035 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
KMKKNLJM_04036 1.5e-34 S Protein of unknown function (DUF2651)
KMKKNLJM_04037 2.3e-256 glpT G -transporter
KMKKNLJM_04038 8.2e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KMKKNLJM_04039 1.8e-290 ybeC E amino acid
KMKKNLJM_04040 4.9e-41 ybyB
KMKKNLJM_04041 2.3e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KMKKNLJM_04042 2e-107 ybxI 3.5.2.6 V beta-lactamase
KMKKNLJM_04043 4.9e-30 ybxH S Family of unknown function (DUF5370)
KMKKNLJM_04044 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
KMKKNLJM_04045 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KMKKNLJM_04046 9.8e-214 ybdO S Domain of unknown function (DUF4885)
KMKKNLJM_04047 1.2e-152 ybdN
KMKKNLJM_04048 6.1e-140 KLT Protein tyrosine kinase
KMKKNLJM_04050 1.1e-170 T His Kinase A (phospho-acceptor) domain
KMKKNLJM_04051 8.5e-122 T Transcriptional regulatory protein, C terminal
KMKKNLJM_04052 9e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KMKKNLJM_04053 2.5e-56
KMKKNLJM_04054 4.5e-203 ybcL EGP Major facilitator Superfamily
KMKKNLJM_04055 5.1e-50 ybzH K Helix-turn-helix domain
KMKKNLJM_04056 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
KMKKNLJM_04057 1.9e-46
KMKKNLJM_04059 2.2e-93 can 4.2.1.1 P carbonic anhydrase
KMKKNLJM_04060 0.0 ybcC S Belongs to the UPF0753 family
KMKKNLJM_04061 2.7e-269 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KMKKNLJM_04062 1.6e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KMKKNLJM_04063 6.4e-119 adaA 3.2.2.21 K Transcriptional regulator
KMKKNLJM_04064 2e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KMKKNLJM_04066 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KMKKNLJM_04067 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KMKKNLJM_04068 3e-225 ybbR S protein conserved in bacteria
KMKKNLJM_04069 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KMKKNLJM_04070 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KMKKNLJM_04071 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KMKKNLJM_04077 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KMKKNLJM_04078 1.9e-86 ybbJ J acetyltransferase
KMKKNLJM_04079 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KMKKNLJM_04080 1.4e-150 ybbH K transcriptional
KMKKNLJM_04081 4.9e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KMKKNLJM_04082 3.8e-226 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KMKKNLJM_04083 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KMKKNLJM_04084 7.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
KMKKNLJM_04085 5.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KMKKNLJM_04086 1.6e-153 feuA P Iron-uptake system-binding protein
KMKKNLJM_04087 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_04088 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KMKKNLJM_04089 1.6e-140 ybbA S Putative esterase
KMKKNLJM_04090 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
KMKKNLJM_04091 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KMKKNLJM_04092 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KMKKNLJM_04093 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KMKKNLJM_04094 1.2e-84 gerD
KMKKNLJM_04095 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KMKKNLJM_04096 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KMKKNLJM_04097 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KMKKNLJM_04098 4.1e-144 ybaJ Q Methyltransferase domain
KMKKNLJM_04099 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KMKKNLJM_04100 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KMKKNLJM_04101 4.1e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KMKKNLJM_04102 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMKKNLJM_04103 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMKKNLJM_04104 7.3e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KMKKNLJM_04105 3.6e-58 rplQ J Ribosomal protein L17
KMKKNLJM_04106 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMKKNLJM_04107 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KMKKNLJM_04108 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KMKKNLJM_04109 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KMKKNLJM_04110 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KMKKNLJM_04111 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KMKKNLJM_04112 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KMKKNLJM_04113 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KMKKNLJM_04114 1.8e-72 rplO J binds to the 23S rRNA
KMKKNLJM_04115 1.9e-23 rpmD J Ribosomal protein L30
KMKKNLJM_04116 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KMKKNLJM_04117 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KMKKNLJM_04118 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KMKKNLJM_04119 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KMKKNLJM_04120 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KMKKNLJM_04121 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KMKKNLJM_04122 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KMKKNLJM_04123 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KMKKNLJM_04124 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KMKKNLJM_04125 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KMKKNLJM_04126 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KMKKNLJM_04127 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KMKKNLJM_04128 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KMKKNLJM_04129 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KMKKNLJM_04130 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KMKKNLJM_04131 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KMKKNLJM_04132 3e-105 rplD J Forms part of the polypeptide exit tunnel
KMKKNLJM_04133 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KMKKNLJM_04134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KMKKNLJM_04135 4.5e-185 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KMKKNLJM_04136 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KMKKNLJM_04137 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KMKKNLJM_04138 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KMKKNLJM_04139 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KMKKNLJM_04140 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KMKKNLJM_04141 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMKKNLJM_04142 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KMKKNLJM_04143 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KMKKNLJM_04144 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KMKKNLJM_04145 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KMKKNLJM_04146 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KMKKNLJM_04147 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KMKKNLJM_04148 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KMKKNLJM_04149 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KMKKNLJM_04150 4.4e-115 sigH K Belongs to the sigma-70 factor family
KMKKNLJM_04151 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KMKKNLJM_04152 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KMKKNLJM_04153 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KMKKNLJM_04154 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KMKKNLJM_04155 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KMKKNLJM_04156 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KMKKNLJM_04157 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KMKKNLJM_04158 5.5e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KMKKNLJM_04159 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KMKKNLJM_04160 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KMKKNLJM_04161 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KMKKNLJM_04162 0.0 clpC O Belongs to the ClpA ClpB family
KMKKNLJM_04163 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KMKKNLJM_04164 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KMKKNLJM_04165 2.9e-76 ctsR K Belongs to the CtsR family
KMKKNLJM_04166 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KMKKNLJM_04167 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KMKKNLJM_04168 4.1e-30 yazB K transcriptional
KMKKNLJM_04169 1.5e-86 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KMKKNLJM_04170 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KMKKNLJM_04171 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KMKKNLJM_04172 8.7e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KMKKNLJM_04173 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KMKKNLJM_04174 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KMKKNLJM_04175 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KMKKNLJM_04176 7.7e-152 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KMKKNLJM_04177 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KMKKNLJM_04178 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KMKKNLJM_04179 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KMKKNLJM_04180 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KMKKNLJM_04181 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KMKKNLJM_04182 3.7e-185 KLT serine threonine protein kinase
KMKKNLJM_04183 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KMKKNLJM_04184 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KMKKNLJM_04187 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KMKKNLJM_04188 1.1e-44 divIC D Septum formation initiator
KMKKNLJM_04189 1.1e-107 yabQ S spore cortex biosynthesis protein
KMKKNLJM_04190 1.5e-49 yabP S Sporulation protein YabP
KMKKNLJM_04191 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KMKKNLJM_04192 9.5e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KMKKNLJM_04193 1.6e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KMKKNLJM_04194 1.5e-92 spoVT K stage V sporulation protein
KMKKNLJM_04195 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KMKKNLJM_04196 2.4e-39 yabK S Peptide ABC transporter permease
KMKKNLJM_04197 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KMKKNLJM_04198 8.7e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KMKKNLJM_04199 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KMKKNLJM_04200 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KMKKNLJM_04201 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KMKKNLJM_04202 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KMKKNLJM_04203 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KMKKNLJM_04204 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KMKKNLJM_04205 8.3e-27 sspF S DNA topological change
KMKKNLJM_04206 7.8e-39 veg S protein conserved in bacteria
KMKKNLJM_04207 4.7e-136 yabG S peptidase
KMKKNLJM_04208 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KMKKNLJM_04209 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KMKKNLJM_04210 2e-167 rpfB GH23 T protein conserved in bacteria
KMKKNLJM_04211 5.9e-143 tatD L hydrolase, TatD
KMKKNLJM_04212 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KMKKNLJM_04213 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KMKKNLJM_04214 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KMKKNLJM_04215 1.5e-49 yazA L endonuclease containing a URI domain
KMKKNLJM_04216 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KMKKNLJM_04217 4.8e-31 yabA L Involved in initiation control of chromosome replication
KMKKNLJM_04218 6.1e-146 yaaT S stage 0 sporulation protein
KMKKNLJM_04219 1.1e-181 holB 2.7.7.7 L DNA polymerase III
KMKKNLJM_04220 1.5e-71 yaaR S protein conserved in bacteria
KMKKNLJM_04221 2.2e-54 yaaQ S protein conserved in bacteria
KMKKNLJM_04222 2.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KMKKNLJM_04223 6e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KMKKNLJM_04224 9.9e-203 yaaN P Belongs to the TelA family
KMKKNLJM_04225 5.8e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KMKKNLJM_04226 3.4e-31 csfB S Inhibitor of sigma-G Gin
KMKKNLJM_04227 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KMKKNLJM_04228 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KMKKNLJM_04229 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KMKKNLJM_04230 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KMKKNLJM_04231 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KMKKNLJM_04232 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KMKKNLJM_04233 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
KMKKNLJM_04234 1.2e-212 yaaH M Glycoside Hydrolase Family
KMKKNLJM_04235 1e-113 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KMKKNLJM_04236 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KMKKNLJM_04237 1.3e-09
KMKKNLJM_04238 3.6e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KMKKNLJM_04239 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KMKKNLJM_04240 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KMKKNLJM_04241 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KMKKNLJM_04242 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KMKKNLJM_04243 1e-181 yaaC S YaaC-like Protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)