ORF_ID e_value Gene_name EC_number CAZy COGs Description
HAGICGNN_00001 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_00002 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HAGICGNN_00003 1.3e-61 yngL S Protein of unknown function (DUF1360)
HAGICGNN_00004 2.2e-290 yngK T Glycosyl hydrolase-like 10
HAGICGNN_00005 6.1e-205 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HAGICGNN_00006 1.4e-306 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HAGICGNN_00007 4e-240 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HAGICGNN_00008 6.2e-29 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HAGICGNN_00009 1.6e-155 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HAGICGNN_00010 1.2e-124 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HAGICGNN_00011 1.7e-279 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HAGICGNN_00012 1e-226 nrnB S phosphohydrolase (DHH superfamily)
HAGICGNN_00013 1.2e-101 yngC S membrane-associated protein
HAGICGNN_00014 4.9e-157 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HAGICGNN_00015 2.5e-68 yngA S membrane
HAGICGNN_00016 1.4e-204 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HAGICGNN_00017 0.0 nrsA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_00018 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_00019 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_00020 5.6e-286 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HAGICGNN_00021 1.5e-239 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HAGICGNN_00022 1.3e-207 S Platelet-activating factor acetylhydrolase, isoform II
HAGICGNN_00024 2.6e-275 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HAGICGNN_00025 4.8e-244 agcS E Sodium alanine symporter
HAGICGNN_00026 3.6e-55 ynfC
HAGICGNN_00027 2.3e-12
HAGICGNN_00028 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAGICGNN_00029 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HAGICGNN_00030 9.9e-65 yccU S CoA-binding protein
HAGICGNN_00031 1.2e-92 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HAGICGNN_00032 5.9e-48 yneR S Belongs to the HesB IscA family
HAGICGNN_00033 1.1e-52 yneQ
HAGICGNN_00034 1.2e-73 yneP S Thioesterase-like superfamily
HAGICGNN_00035 8.6e-35 tlp S Belongs to the Tlp family
HAGICGNN_00036 4e-08 sspN S Small acid-soluble spore protein N family
HAGICGNN_00038 4.1e-84 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HAGICGNN_00039 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HAGICGNN_00040 3.8e-14 sspO S Belongs to the SspO family
HAGICGNN_00041 3.9e-19 sspP S Belongs to the SspP family
HAGICGNN_00042 3.3e-59 hspX O Spore coat protein
HAGICGNN_00043 1.4e-69 yneK S Protein of unknown function (DUF2621)
HAGICGNN_00044 3.6e-74 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HAGICGNN_00045 8.8e-57 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HAGICGNN_00046 1.2e-123 ccdA O cytochrome c biogenesis protein
HAGICGNN_00047 1.2e-14 ynzD S Spo0E like sporulation regulatory protein
HAGICGNN_00048 1.8e-28 yneF S UPF0154 protein
HAGICGNN_00049 1.7e-78 yneE S Sporulation inhibitor of replication protein sirA
HAGICGNN_00050 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HAGICGNN_00051 1.6e-30 ynzC S UPF0291 protein
HAGICGNN_00052 5.6e-110 yneB L resolvase
HAGICGNN_00053 1.4e-47 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HAGICGNN_00054 6.4e-108 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HAGICGNN_00055 1.4e-69 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HAGICGNN_00056 1.4e-74 yndM S Protein of unknown function (DUF2512)
HAGICGNN_00057 5.3e-128 yndL S Replication protein
HAGICGNN_00059 1.6e-270 yndJ S YndJ-like protein
HAGICGNN_00060 6e-85 yndH S Domain of unknown function (DUF4166)
HAGICGNN_00061 1.1e-134 yndG S DoxX-like family
HAGICGNN_00062 1e-189 gerLC S Spore germination protein
HAGICGNN_00063 2e-184 gerAB U Spore germination
HAGICGNN_00064 1.1e-268 gerAA EG Spore germination protein
HAGICGNN_00065 6.9e-175 chrA P chromate transporter, chromate ion transporter
HAGICGNN_00068 4.1e-69 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HAGICGNN_00069 1.5e-65
HAGICGNN_00070 4.3e-23 tatA U protein secretion
HAGICGNN_00074 1.9e-122 S Domain of unknown function, YrpD
HAGICGNN_00078 2.4e-158 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAGICGNN_00079 6.1e-07 S Protein of unknown function (DUF1643)
HAGICGNN_00080 1.7e-75 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HAGICGNN_00081 5.7e-69 yncE S Protein of unknown function (DUF2691)
HAGICGNN_00083 1.9e-201 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAGICGNN_00084 3.2e-35 iolT EGP Major facilitator Superfamily
HAGICGNN_00085 7.1e-104 yrkJ S membrane transporter protein
HAGICGNN_00086 7.3e-33 yrkI O Belongs to the sulfur carrier protein TusA family
HAGICGNN_00087 1.4e-196 yrkH P Rhodanese Homology Domain
HAGICGNN_00088 2.5e-57 perX S DsrE/DsrF-like family
HAGICGNN_00089 4e-85 yrkF OP Belongs to the sulfur carrier protein TusA family
HAGICGNN_00090 1.7e-52 P Rhodanese Homology Domain
HAGICGNN_00091 2.8e-70 yrkE O DsrE/DsrF/DrsH-like family
HAGICGNN_00092 7.8e-39 yrkD S protein conserved in bacteria
HAGICGNN_00093 6.7e-28
HAGICGNN_00094 4.9e-08 3.2.1.8 G Glycosyl hydrolases family 11
HAGICGNN_00095 2.7e-277 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HAGICGNN_00096 4e-248 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HAGICGNN_00097 2.2e-210 xylR GK ROK family
HAGICGNN_00098 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HAGICGNN_00099 3.9e-246 xynT G MFS/sugar transport protein
HAGICGNN_00100 4.4e-73 yhbS S family acetyltransferase
HAGICGNN_00101 2.1e-71 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HAGICGNN_00104 8.9e-100 ynaE S Domain of unknown function (DUF3885)
HAGICGNN_00105 0.0 pps 2.7.9.2 GT Phosphoenolpyruvate synthase
HAGICGNN_00106 3.7e-124 ynaC
HAGICGNN_00107 5.3e-63 G SMI1-KNR4 cell-wall
HAGICGNN_00108 2.4e-53
HAGICGNN_00109 7.8e-36
HAGICGNN_00110 6.7e-106 yokF 3.1.31.1 L RNA catabolic process
HAGICGNN_00111 8.7e-126 rsbW 2.4.1.12, 2.7.11.1 GT2 T sigma factor antagonist activity
HAGICGNN_00112 8.7e-283 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HAGICGNN_00113 2.3e-81 S SMI1-KNR4 cell-wall
HAGICGNN_00114 2.6e-124 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HAGICGNN_00115 3.5e-31 xhlB S SPP1 phage holin
HAGICGNN_00116 3e-28 bhlA S BhlA holin family
HAGICGNN_00119 1.6e-62
HAGICGNN_00122 3.4e-59
HAGICGNN_00123 1.3e-219 NU Prophage endopeptidase tail
HAGICGNN_00124 4.1e-105 S Phage tail protein
HAGICGNN_00125 0.0 D phage tail tape measure protein
HAGICGNN_00128 2e-77 S Phage tail tube protein
HAGICGNN_00130 2e-49 S Bacteriophage HK97-gp10, putative tail-component
HAGICGNN_00131 1e-37 S Phage head-tail joining protein
HAGICGNN_00132 4.8e-40 S Phage gp6-like head-tail connector protein
HAGICGNN_00133 1.9e-19
HAGICGNN_00134 3.5e-156 gp36 S capsid protein
HAGICGNN_00135 4.4e-80 S peptidase activity
HAGICGNN_00136 2.4e-173 S Phage portal protein
HAGICGNN_00137 4.3e-303 S Terminase
HAGICGNN_00138 4e-79 L phage terminase small subunit
HAGICGNN_00139 1.7e-47 V HNH endonuclease
HAGICGNN_00140 5.5e-44 T Histidine kinase
HAGICGNN_00144 1.7e-58
HAGICGNN_00148 2.3e-79
HAGICGNN_00149 2.3e-93 S nuclease activity
HAGICGNN_00150 4.9e-62
HAGICGNN_00151 0.0 S hydrolase activity
HAGICGNN_00152 2.4e-72 S Protein of unknown function (DUF669)
HAGICGNN_00154 3.1e-162 tadZ D AAA domain
HAGICGNN_00155 1.2e-92 S DNA protection
HAGICGNN_00158 6.1e-18 S Uncharacterized protein YqaH
HAGICGNN_00160 9.7e-20
HAGICGNN_00161 4.8e-52 S Phage regulatory protein Rha (Phage_pRha)
HAGICGNN_00163 1.1e-12 K sequence-specific DNA binding
HAGICGNN_00164 3.7e-50 1.15.1.2 E Pfam:DUF955
HAGICGNN_00165 1.4e-135 L Belongs to the 'phage' integrase family
HAGICGNN_00166 4.3e-258 glnA 6.3.1.2 E glutamine synthetase
HAGICGNN_00167 1.1e-68 glnR K transcriptional
HAGICGNN_00168 1.7e-240 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HAGICGNN_00169 1.3e-227 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HAGICGNN_00170 1.2e-174 spoVK O stage V sporulation protein K
HAGICGNN_00171 1.5e-109 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HAGICGNN_00172 3.7e-103 ymaB
HAGICGNN_00173 1.2e-185 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAGICGNN_00174 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HAGICGNN_00175 1.5e-65 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HAGICGNN_00176 1.3e-21 ymzA
HAGICGNN_00177 5.1e-25
HAGICGNN_00178 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HAGICGNN_00179 1.2e-169 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HAGICGNN_00180 8.1e-43 ymaF S YmaF family
HAGICGNN_00182 5.9e-49 ebrA P Small Multidrug Resistance protein
HAGICGNN_00183 1.6e-50 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HAGICGNN_00184 3.1e-75 ymaD O redox protein, regulator of disulfide bond formation
HAGICGNN_00185 2.6e-121 ymaC S Replication protein
HAGICGNN_00186 1.1e-07 K Transcriptional regulator
HAGICGNN_00187 4.3e-242 aprX O Belongs to the peptidase S8 family
HAGICGNN_00188 3.7e-151 ymaE S Metallo-beta-lactamase superfamily
HAGICGNN_00189 5.1e-57 ymzB
HAGICGNN_00190 1.4e-223 cypA C Cytochrome P450
HAGICGNN_00191 0.0 pks13 HQ Beta-ketoacyl synthase
HAGICGNN_00192 0.0 dhbF IQ polyketide synthase
HAGICGNN_00193 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HAGICGNN_00194 0.0 pfaA Q Polyketide synthase of type I
HAGICGNN_00195 0.0 rhiB IQ polyketide synthase
HAGICGNN_00196 1.6e-129 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HAGICGNN_00197 4.2e-133 pksH 4.2.1.18 I enoyl-CoA hydratase
HAGICGNN_00198 4.6e-238 pksG 2.3.3.10 I synthase
HAGICGNN_00199 5.6e-220 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAGICGNN_00200 4.1e-37 acpK IQ Phosphopantetheine attachment site
HAGICGNN_00201 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HAGICGNN_00202 5.1e-160 pksD Q Acyl transferase domain
HAGICGNN_00203 2.5e-150 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HAGICGNN_00204 3.1e-119 pksB 3.1.2.6 S Polyketide biosynthesis
HAGICGNN_00205 6.7e-97 pksA K Transcriptional regulator
HAGICGNN_00206 2.7e-89 ymcC S Membrane
HAGICGNN_00207 6.2e-52 S Regulatory protein YrvL
HAGICGNN_00208 2.4e-16 plnP S CAAX protease self-immunity
HAGICGNN_00209 1.8e-13 plnP S CAAX protease self-immunity
HAGICGNN_00210 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HAGICGNN_00211 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HAGICGNN_00212 2.2e-88 cotE S Spore coat protein
HAGICGNN_00213 1.2e-65 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HAGICGNN_00214 9.4e-294 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HAGICGNN_00215 1.5e-206 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HAGICGNN_00216 1.6e-180 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HAGICGNN_00217 1.2e-36 spoVS S Stage V sporulation protein S
HAGICGNN_00218 7.4e-149 ymdB S protein conserved in bacteria
HAGICGNN_00219 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HAGICGNN_00220 6.1e-200 pbpX V Beta-lactamase
HAGICGNN_00221 4.9e-185 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HAGICGNN_00222 1.2e-230 cinA 3.5.1.42 S Belongs to the CinA family
HAGICGNN_00223 4.6e-100 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAGICGNN_00224 1.7e-120 ymfM S protein conserved in bacteria
HAGICGNN_00225 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HAGICGNN_00226 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HAGICGNN_00227 1.7e-120 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HAGICGNN_00228 2e-236 ymfH S zinc protease
HAGICGNN_00229 2.1e-222 ymfF S Peptidase M16
HAGICGNN_00230 2.2e-200 ymfD EGP Major facilitator Superfamily
HAGICGNN_00231 2.8e-131 ymfC K Transcriptional regulator
HAGICGNN_00232 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HAGICGNN_00233 2.2e-31 S YlzJ-like protein
HAGICGNN_00234 2.3e-128 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HAGICGNN_00235 2.4e-306 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAGICGNN_00236 1.7e-154 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HAGICGNN_00237 2.1e-219 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HAGICGNN_00238 7.8e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HAGICGNN_00239 3.7e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HAGICGNN_00240 8.6e-146 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HAGICGNN_00241 1.1e-40 ymxH S YlmC YmxH family
HAGICGNN_00242 7e-231 pepR S Belongs to the peptidase M16 family
HAGICGNN_00243 5e-176 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HAGICGNN_00244 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HAGICGNN_00245 1e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HAGICGNN_00246 8.5e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HAGICGNN_00247 1.2e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HAGICGNN_00248 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HAGICGNN_00249 8.6e-44 ylxP S protein conserved in bacteria
HAGICGNN_00250 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HAGICGNN_00251 3.1e-47 ylxQ J ribosomal protein
HAGICGNN_00252 3.2e-35 ylxR K nucleic-acid-binding protein implicated in transcription termination
HAGICGNN_00253 1.6e-202 nusA K Participates in both transcription termination and antitermination
HAGICGNN_00254 2.1e-79 rimP S Required for maturation of 30S ribosomal subunits
HAGICGNN_00255 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAGICGNN_00256 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HAGICGNN_00257 7.2e-231 rasP M zinc metalloprotease
HAGICGNN_00258 1.4e-212 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HAGICGNN_00259 5.5e-136 cdsA 2.7.7.41 S Belongs to the CDS family
HAGICGNN_00260 6e-143 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HAGICGNN_00261 4.2e-90 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HAGICGNN_00262 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HAGICGNN_00263 3.8e-154 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HAGICGNN_00264 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HAGICGNN_00265 1.4e-60 ylxL
HAGICGNN_00266 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_00267 3.6e-85 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HAGICGNN_00268 4.1e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HAGICGNN_00269 1.2e-77 cheW NT COG0835 Chemotaxis signal transduction protein
HAGICGNN_00270 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HAGICGNN_00271 6e-186 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HAGICGNN_00272 9.5e-153 flhG D Belongs to the ParA family
HAGICGNN_00273 1.8e-185 flhF N Flagellar biosynthesis regulator FlhF
HAGICGNN_00274 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAGICGNN_00275 6.4e-188 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HAGICGNN_00276 3.4e-130 fliR N Flagellar biosynthetic protein FliR
HAGICGNN_00277 3.3e-35 fliQ N Role in flagellar biosynthesis
HAGICGNN_00278 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HAGICGNN_00279 4.8e-93 fliZ N Flagellar biosynthesis protein, FliO
HAGICGNN_00280 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HAGICGNN_00281 5.8e-163 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HAGICGNN_00282 9.2e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HAGICGNN_00283 1.3e-46 fliL N Controls the rotational direction of flagella during chemotaxis
HAGICGNN_00284 1.9e-136 flgG N Flagellar basal body rod
HAGICGNN_00285 8.1e-62 flgD N Flagellar basal body rod modification protein
HAGICGNN_00286 1.3e-170 fliK N Flagellar hook-length control protein
HAGICGNN_00287 1.8e-33 ylxF S MgtE intracellular N domain
HAGICGNN_00288 2.7e-68 fliJ N Flagellar biosynthesis chaperone
HAGICGNN_00289 9.8e-239 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HAGICGNN_00290 1.1e-101 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HAGICGNN_00291 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HAGICGNN_00292 3.1e-247 fliF N The M ring may be actively involved in energy transduction
HAGICGNN_00293 3.5e-28 fliE N Flagellar hook-basal body
HAGICGNN_00294 5.8e-74 flgC N Belongs to the flagella basal body rod proteins family
HAGICGNN_00295 2.2e-61 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HAGICGNN_00296 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HAGICGNN_00297 1.4e-238 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HAGICGNN_00298 5.7e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HAGICGNN_00299 2.2e-168 xerC L tyrosine recombinase XerC
HAGICGNN_00300 9.1e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HAGICGNN_00301 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAGICGNN_00302 2.8e-152 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HAGICGNN_00303 1.2e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HAGICGNN_00304 2.2e-210 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HAGICGNN_00305 1.5e-43 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HAGICGNN_00306 8e-257 ylqG
HAGICGNN_00307 2.7e-124 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAGICGNN_00308 2.7e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HAGICGNN_00309 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HAGICGNN_00310 7.3e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HAGICGNN_00311 4.2e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HAGICGNN_00312 3.1e-60 ylqD S YlqD protein
HAGICGNN_00313 1.7e-35 ylqC S Belongs to the UPF0109 family
HAGICGNN_00314 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HAGICGNN_00315 4.3e-234 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HAGICGNN_00316 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HAGICGNN_00317 6.2e-82
HAGICGNN_00318 2.3e-171 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HAGICGNN_00319 0.0 smc D Required for chromosome condensation and partitioning
HAGICGNN_00320 4.4e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HAGICGNN_00321 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HAGICGNN_00322 3.9e-128 IQ reductase
HAGICGNN_00323 2.1e-166 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HAGICGNN_00324 1.3e-174 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HAGICGNN_00325 3.7e-78 fapR K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HAGICGNN_00326 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HAGICGNN_00327 2.1e-152 sdaAA 4.3.1.17 E L-serine dehydratase
HAGICGNN_00328 6.2e-117 sdaAB 4.3.1.17 E L-serine dehydratase
HAGICGNN_00329 1.1e-292 yloV S kinase related to dihydroxyacetone kinase
HAGICGNN_00330 5.5e-59 asp S protein conserved in bacteria
HAGICGNN_00331 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HAGICGNN_00332 6.7e-116 thiN 2.7.6.2 H thiamine pyrophosphokinase
HAGICGNN_00333 1e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HAGICGNN_00334 6.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HAGICGNN_00335 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HAGICGNN_00336 4.8e-137 stp 3.1.3.16 T phosphatase
HAGICGNN_00337 1.9e-203 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HAGICGNN_00338 2.4e-245 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HAGICGNN_00339 3.1e-170 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HAGICGNN_00340 1.6e-82 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAGICGNN_00341 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAGICGNN_00342 1.4e-215 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HAGICGNN_00343 8.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HAGICGNN_00344 1.2e-109 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HAGICGNN_00345 1.5e-40 ylzA S Belongs to the UPF0296 family
HAGICGNN_00346 2.1e-152 yloC S stress-induced protein
HAGICGNN_00347 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HAGICGNN_00348 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HAGICGNN_00349 4.5e-72 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HAGICGNN_00350 1.8e-139 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HAGICGNN_00351 4.5e-143 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HAGICGNN_00352 4e-107 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HAGICGNN_00353 6.3e-218 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HAGICGNN_00354 1.1e-174 cysP P phosphate transporter
HAGICGNN_00355 1.2e-139 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HAGICGNN_00356 8.3e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HAGICGNN_00357 4.2e-119 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HAGICGNN_00358 8.9e-170 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HAGICGNN_00359 3.2e-141 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HAGICGNN_00360 0.0 carB 6.3.5.5 F Belongs to the CarB family
HAGICGNN_00361 1.1e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HAGICGNN_00362 6.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HAGICGNN_00363 1.1e-159 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HAGICGNN_00364 6.7e-232 pyrP F Xanthine uracil
HAGICGNN_00365 5.2e-93 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HAGICGNN_00366 1.6e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAGICGNN_00367 2e-77 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HAGICGNN_00368 8e-61 dksA T COG1734 DnaK suppressor protein
HAGICGNN_00370 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HAGICGNN_00371 4.4e-67 divIVA D Cell division initiation protein
HAGICGNN_00372 1.9e-133 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HAGICGNN_00373 1.3e-39 yggT S membrane
HAGICGNN_00374 6.9e-59 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HAGICGNN_00375 3.3e-121 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HAGICGNN_00376 1e-153 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HAGICGNN_00377 3.1e-37 ylmC S sporulation protein
HAGICGNN_00378 1.3e-235 argE 3.5.1.16 E Acetylornithine deacetylase
HAGICGNN_00379 3.9e-142 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HAGICGNN_00380 1.1e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_00381 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_00382 9.5e-167 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HAGICGNN_00383 0.0 bpr O COG1404 Subtilisin-like serine proteases
HAGICGNN_00384 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HAGICGNN_00385 1.6e-228 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HAGICGNN_00386 6.2e-58 sbp S small basic protein
HAGICGNN_00387 9.4e-113 ylxX S protein conserved in bacteria
HAGICGNN_00388 5.9e-102 ylxW S protein conserved in bacteria
HAGICGNN_00389 1.1e-131 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HAGICGNN_00390 1.7e-165 murB 1.3.1.98 M cell wall formation
HAGICGNN_00391 4.1e-198 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HAGICGNN_00392 2.2e-185 spoVE D Belongs to the SEDS family
HAGICGNN_00393 3.7e-249 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HAGICGNN_00394 5.5e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HAGICGNN_00395 1.4e-273 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HAGICGNN_00396 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HAGICGNN_00397 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HAGICGNN_00398 7.8e-42 ftsL D Essential cell division protein
HAGICGNN_00399 1.5e-169 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HAGICGNN_00400 2.9e-78 mraZ K Belongs to the MraZ family
HAGICGNN_00401 6.9e-295 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HAGICGNN_00402 1.3e-154 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAGICGNN_00403 1.6e-85 ylbP K n-acetyltransferase
HAGICGNN_00404 1.3e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HAGICGNN_00405 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HAGICGNN_00406 3.6e-88 yceD S metal-binding, possibly nucleic acid-binding protein
HAGICGNN_00408 2e-217 ylbM S Belongs to the UPF0348 family
HAGICGNN_00409 1.1e-181 ylbL T Belongs to the peptidase S16 family
HAGICGNN_00410 2.4e-136 ylbK S esterase of the alpha-beta hydrolase superfamily
HAGICGNN_00411 1.7e-213 ylbJ S Sporulation integral membrane protein YlbJ
HAGICGNN_00412 5.6e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HAGICGNN_00413 9.2e-98 rsmD 2.1.1.171 L Methyltransferase
HAGICGNN_00414 9.8e-39 ylbG S UPF0298 protein
HAGICGNN_00415 5.2e-75 ylbF S Belongs to the UPF0342 family
HAGICGNN_00416 1.5e-36 ylbE S YlbE-like protein
HAGICGNN_00417 1.2e-59 ylbD S Putative coat protein
HAGICGNN_00418 1.1e-195 ylbC S protein with SCP PR1 domains
HAGICGNN_00419 2.6e-74 ylbB T COG0517 FOG CBS domain
HAGICGNN_00420 2.2e-60 ylbA S YugN-like family
HAGICGNN_00421 2.9e-162 ctaG S cytochrome c oxidase
HAGICGNN_00422 1.7e-51 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HAGICGNN_00423 7.4e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HAGICGNN_00424 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAGICGNN_00425 7.1e-187 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HAGICGNN_00426 5.5e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HAGICGNN_00427 2.5e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HAGICGNN_00428 1e-136 phr 4.1.99.3 L Belongs to the DNA photolyase family
HAGICGNN_00429 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HAGICGNN_00430 3.3e-209 ftsW D Belongs to the SEDS family
HAGICGNN_00431 1.9e-43 ylaN S Belongs to the UPF0358 family
HAGICGNN_00432 2.6e-169 glsA 3.5.1.2 E Belongs to the glutaminase family
HAGICGNN_00433 1.1e-78 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HAGICGNN_00434 5.2e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HAGICGNN_00435 5.4e-86 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAGICGNN_00436 7.3e-32 ylaI S protein conserved in bacteria
HAGICGNN_00437 3.6e-46 ylaH S YlaH-like protein
HAGICGNN_00438 0.0 typA T GTP-binding protein TypA
HAGICGNN_00439 1.8e-21 S Family of unknown function (DUF5325)
HAGICGNN_00440 3.6e-34 ylaE
HAGICGNN_00441 1.4e-12 sigC S Putative zinc-finger
HAGICGNN_00442 7.6e-86 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_00443 2.1e-39 ylaB
HAGICGNN_00444 0.0 ylaA
HAGICGNN_00445 6.3e-285 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HAGICGNN_00446 1.3e-31 K Transcriptional regulator
HAGICGNN_00447 1.7e-149 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HAGICGNN_00448 2.7e-74 ykzC S Acetyltransferase (GNAT) family
HAGICGNN_00449 1.7e-145 suhB 3.1.3.25 G Inositol monophosphatase
HAGICGNN_00450 9.3e-26 ykzI
HAGICGNN_00451 6.6e-116 yktB S Belongs to the UPF0637 family
HAGICGNN_00452 1e-41 yktA S Belongs to the UPF0223 family
HAGICGNN_00453 6.1e-274 speA 4.1.1.19 E Arginine
HAGICGNN_00454 2.7e-10 S SR1 protein
HAGICGNN_00455 1.8e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HAGICGNN_00456 2e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAGICGNN_00457 1.1e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAGICGNN_00458 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAGICGNN_00459 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAGICGNN_00460 1.1e-100 recN L Putative cell-wall binding lipoprotein
HAGICGNN_00462 8.3e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HAGICGNN_00463 3.4e-141 ykrA S hydrolases of the HAD superfamily
HAGICGNN_00464 4.1e-30 ykzG S Belongs to the UPF0356 family
HAGICGNN_00465 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HAGICGNN_00466 3.5e-305 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HAGICGNN_00467 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HAGICGNN_00468 2.8e-143 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HAGICGNN_00469 5.2e-235 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HAGICGNN_00470 1.9e-43 abrB K of stationary sporulation gene expression
HAGICGNN_00471 1.9e-181 mreB D Rod-share determining protein MreBH
HAGICGNN_00472 1.1e-12 S Uncharacterized protein YkpC
HAGICGNN_00473 9.8e-233 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HAGICGNN_00474 1e-154 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HAGICGNN_00475 3.2e-308 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAGICGNN_00476 1.5e-37 ykoA
HAGICGNN_00477 1.2e-103 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HAGICGNN_00478 2.4e-310 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HAGICGNN_00479 1.2e-163 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HAGICGNN_00480 4.9e-134 fruR K Transcriptional regulator
HAGICGNN_00481 3.5e-203 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HAGICGNN_00482 4.1e-119 macB V ABC transporter, ATP-binding protein
HAGICGNN_00483 1.9e-150 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HAGICGNN_00484 4.2e-108 yknW S Yip1 domain
HAGICGNN_00485 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HAGICGNN_00486 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HAGICGNN_00487 9.1e-31 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HAGICGNN_00488 5.1e-81 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HAGICGNN_00489 1.8e-87 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HAGICGNN_00490 1.9e-234 moeA 2.10.1.1 H molybdopterin
HAGICGNN_00491 7.4e-186 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HAGICGNN_00492 1.3e-97 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HAGICGNN_00493 2.1e-105 yknT
HAGICGNN_00494 3.2e-93 rok K Repressor of ComK
HAGICGNN_00495 5.1e-78 ykuV CO thiol-disulfide
HAGICGNN_00496 1.9e-100 ykuU O Alkyl hydroperoxide reductase
HAGICGNN_00497 1.7e-137 ykuT M Mechanosensitive ion channel
HAGICGNN_00498 5.8e-36 ykuS S Belongs to the UPF0180 family
HAGICGNN_00499 3e-212 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HAGICGNN_00500 5.3e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HAGICGNN_00501 4e-75 fld C Flavodoxin
HAGICGNN_00502 2.2e-165 ykuO
HAGICGNN_00503 6.3e-79 fld C Flavodoxin domain
HAGICGNN_00504 9.6e-166 ccpC K Transcriptional regulator
HAGICGNN_00505 1e-75 ykuL S CBS domain
HAGICGNN_00506 3.9e-27 ykzF S Antirepressor AbbA
HAGICGNN_00507 2.4e-92 ykuK S Ribonuclease H-like
HAGICGNN_00508 3.9e-37 ykuJ S protein conserved in bacteria
HAGICGNN_00509 4.8e-232 ykuI T Diguanylate phosphodiesterase
HAGICGNN_00510 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_00511 1.4e-156 ykuE S Metallophosphoesterase
HAGICGNN_00512 9.7e-84 ykuD S protein conserved in bacteria
HAGICGNN_00513 2.7e-233 ykuC EGP Major facilitator Superfamily
HAGICGNN_00514 4.9e-84 ykyB S YkyB-like protein
HAGICGNN_00515 1.2e-166 cheV 2.7.13.3 T Chemotaxis protein CheV
HAGICGNN_00516 4.9e-15
HAGICGNN_00517 2e-219 patA 2.6.1.1 E Aminotransferase
HAGICGNN_00518 0.0 pilS 2.7.13.3 T Histidine kinase
HAGICGNN_00519 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HAGICGNN_00520 2.1e-114 ykwD J protein with SCP PR1 domains
HAGICGNN_00521 3.1e-156 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HAGICGNN_00522 3.4e-235 mcpC NT chemotaxis protein
HAGICGNN_00523 2.9e-117 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_00524 4.1e-200 splB 4.1.99.14 L Spore photoproduct lyase
HAGICGNN_00525 7.2e-39 splA S Transcriptional regulator
HAGICGNN_00526 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HAGICGNN_00527 3.6e-39 ptsH G phosphocarrier protein HPr
HAGICGNN_00528 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_00529 2.7e-125 glcT K antiterminator
HAGICGNN_00530 1.1e-162 ykvZ 5.1.1.1 K Transcriptional regulator
HAGICGNN_00532 5e-204 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HAGICGNN_00534 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HAGICGNN_00535 2.8e-85 stoA CO thiol-disulfide
HAGICGNN_00536 7.9e-236 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_00537 1.8e-94 ykvT 3.5.1.28 M Cell Wall Hydrolase
HAGICGNN_00538 5.2e-27
HAGICGNN_00539 1.7e-24 ykvS S protein conserved in bacteria
HAGICGNN_00540 3.8e-42 ykvR S Protein of unknown function (DUF3219)
HAGICGNN_00541 3.4e-36 yoaW
HAGICGNN_00542 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HAGICGNN_00543 1.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HAGICGNN_00544 8.1e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HAGICGNN_00545 3.6e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HAGICGNN_00546 5.5e-176 ykvI S membrane
HAGICGNN_00547 0.0 clpE O Belongs to the ClpA ClpB family
HAGICGNN_00548 1.4e-137 motA N flagellar motor
HAGICGNN_00549 1.3e-124 motB N Flagellar motor protein
HAGICGNN_00550 1.3e-75 ykvE K transcriptional
HAGICGNN_00551 3e-268 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HAGICGNN_00552 8e-57 eag
HAGICGNN_00553 6.4e-09 S Spo0E like sporulation regulatory protein
HAGICGNN_00554 2.5e-47 XK27_09985 S Protein of unknown function (DUF1232)
HAGICGNN_00555 1.3e-93 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HAGICGNN_00556 2.4e-110 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HAGICGNN_00557 1.1e-130 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HAGICGNN_00558 7.4e-225 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HAGICGNN_00559 1.1e-223 mtnE 2.6.1.83 E Aminotransferase
HAGICGNN_00560 4.2e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HAGICGNN_00561 1.7e-221 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HAGICGNN_00562 2.7e-191 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HAGICGNN_00564 3.2e-81 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HAGICGNN_00565 0.0 kinE 2.7.13.3 T Histidine kinase
HAGICGNN_00566 5e-182 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HAGICGNN_00567 2e-19 ykzE
HAGICGNN_00568 3.5e-10 ydfR S Protein of unknown function (DUF421)
HAGICGNN_00569 3.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HAGICGNN_00570 2.1e-152 htpX O Belongs to the peptidase M48B family
HAGICGNN_00571 7e-119 ykrK S Domain of unknown function (DUF1836)
HAGICGNN_00572 1.9e-26 sspD S small acid-soluble spore protein
HAGICGNN_00573 5.7e-110 rsgI S Anti-sigma factor N-terminus
HAGICGNN_00574 1.8e-128 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_00575 2.3e-134 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HAGICGNN_00576 2.3e-108 ykoX S membrane-associated protein
HAGICGNN_00577 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HAGICGNN_00578 4.4e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HAGICGNN_00579 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HAGICGNN_00580 4.6e-180 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HAGICGNN_00581 0.0 ykoS
HAGICGNN_00582 5.2e-150 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HAGICGNN_00583 3.6e-93 ykoP G polysaccharide deacetylase
HAGICGNN_00584 3.2e-190 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HAGICGNN_00585 3e-81 mhqR K transcriptional
HAGICGNN_00586 9.4e-23 ykoL
HAGICGNN_00587 3.5e-18
HAGICGNN_00588 1.4e-53 tnrA K transcriptional
HAGICGNN_00589 4.9e-217 mgtE P Acts as a magnesium transporter
HAGICGNN_00592 1.9e-73 ykoJ S Peptidase propeptide and YPEB domain
HAGICGNN_00593 2.9e-85 ykoI S Peptidase propeptide and YPEB domain
HAGICGNN_00594 2.5e-229 ykoH 2.7.13.3 T Histidine kinase
HAGICGNN_00595 2.8e-120 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_00596 2.9e-105 ykoF S YKOF-related Family
HAGICGNN_00597 6.7e-94 ykoE S ABC-type cobalt transport system, permease component
HAGICGNN_00598 4e-282 P ABC transporter, ATP-binding protein
HAGICGNN_00599 9e-128 ykoC P Cobalt transport protein
HAGICGNN_00600 1.7e-148 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAGICGNN_00601 2.3e-173 isp O Belongs to the peptidase S8 family
HAGICGNN_00602 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HAGICGNN_00603 4.8e-79 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HAGICGNN_00604 1.7e-159 M Glycosyl transferase family 2
HAGICGNN_00605 2.1e-70 ohrB O Organic hydroperoxide resistance protein
HAGICGNN_00606 4e-68 ohrR K COG1846 Transcriptional regulators
HAGICGNN_00607 9.6e-71 ohrA O Organic hydroperoxide resistance protein
HAGICGNN_00608 5.3e-218 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HAGICGNN_00609 6.5e-196 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAGICGNN_00610 9.9e-166 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HAGICGNN_00611 3.5e-49 ykkD P Multidrug resistance protein
HAGICGNN_00612 1.3e-49 ykkC P Multidrug resistance protein
HAGICGNN_00613 1.6e-88 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAGICGNN_00614 9.7e-89 ykkA S Protein of unknown function (DUF664)
HAGICGNN_00615 5.6e-127 ykjA S Protein of unknown function (DUF421)
HAGICGNN_00616 2.5e-09
HAGICGNN_00617 2.2e-213 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HAGICGNN_00618 1.9e-90 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HAGICGNN_00619 2.1e-149 ykgA E Amidinotransferase
HAGICGNN_00620 1.6e-196 pgl 3.1.1.31 G 6-phosphogluconolactonase
HAGICGNN_00621 3.3e-183 ykfD E Belongs to the ABC transporter superfamily
HAGICGNN_00622 5.5e-153 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HAGICGNN_00623 2.2e-188 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HAGICGNN_00624 1.8e-170 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HAGICGNN_00625 1.7e-309 dppE E ABC transporter substrate-binding protein
HAGICGNN_00626 2.1e-180 dppD P Belongs to the ABC transporter superfamily
HAGICGNN_00627 1.7e-171 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00628 2.9e-157 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00629 4.8e-151 dppA E D-aminopeptidase
HAGICGNN_00630 3.4e-125 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HAGICGNN_00631 8.7e-190 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAGICGNN_00632 1.6e-177 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HAGICGNN_00633 2.4e-298 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAGICGNN_00634 2.2e-176 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HAGICGNN_00635 5.4e-237 steT E amino acid
HAGICGNN_00636 2e-109 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HAGICGNN_00637 1.6e-172 pit P phosphate transporter
HAGICGNN_00638 2.2e-131 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HAGICGNN_00639 5.7e-22 spoIISB S Stage II sporulation protein SB
HAGICGNN_00640 2e-158 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HAGICGNN_00641 7.4e-37 xhlB S SPP1 phage holin
HAGICGNN_00642 2.6e-37 xhlA S Haemolysin XhlA
HAGICGNN_00643 3.2e-134 xepA
HAGICGNN_00644 1.2e-21 xkdX
HAGICGNN_00645 4.6e-52 xkdW S XkdW protein
HAGICGNN_00646 3.1e-308
HAGICGNN_00647 5.6e-40
HAGICGNN_00648 5.5e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HAGICGNN_00649 5.3e-187 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HAGICGNN_00650 4.5e-68 xkdS S Protein of unknown function (DUF2634)
HAGICGNN_00651 6.7e-38 xkdR S Protein of unknown function (DUF2577)
HAGICGNN_00652 3.2e-178 xkdQ G NLP P60 protein
HAGICGNN_00653 9.6e-116 xkdP S Lysin motif
HAGICGNN_00654 7.2e-285 xkdO L Transglycosylase SLT domain
HAGICGNN_00655 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
HAGICGNN_00656 2.3e-75 xkdM S Phage tail tube protein
HAGICGNN_00657 1.8e-251 xkdK S Phage tail sheath C-terminal domain
HAGICGNN_00658 2.4e-72 xkdJ
HAGICGNN_00659 8.1e-82 xkdI S Bacteriophage HK97-gp10, putative tail-component
HAGICGNN_00660 6.4e-60 yqbH S Domain of unknown function (DUF3599)
HAGICGNN_00661 7.6e-59 yqbG S Protein of unknown function (DUF3199)
HAGICGNN_00662 1.3e-168 xkdG S Phage capsid family
HAGICGNN_00663 4.7e-130 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HAGICGNN_00664 4.4e-280 yqbA S portal protein
HAGICGNN_00665 1.4e-245 xtmB S phage terminase, large subunit
HAGICGNN_00666 8.8e-134 xtmA L phage terminase small subunit
HAGICGNN_00667 7.2e-81 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HAGICGNN_00668 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HAGICGNN_00670 4.9e-111 xkdC L Bacterial dnaA protein
HAGICGNN_00671 7.1e-142 xkdB K sequence-specific DNA binding
HAGICGNN_00673 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
HAGICGNN_00674 6.2e-108 xkdA E IrrE N-terminal-like domain
HAGICGNN_00675 1.2e-152 ydbD P Catalase
HAGICGNN_00676 2e-98 yjqB S Pfam:DUF867
HAGICGNN_00677 2.6e-59 yjqA S Bacterial PH domain
HAGICGNN_00678 1.6e-161 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HAGICGNN_00679 1e-35 S YCII-related domain
HAGICGNN_00681 4.3e-211 S response regulator aspartate phosphatase
HAGICGNN_00682 3e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HAGICGNN_00683 5.8e-77 yjoA S DinB family
HAGICGNN_00684 3.7e-129 MA20_18170 S membrane transporter protein
HAGICGNN_00685 7.1e-278 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HAGICGNN_00686 9.6e-264 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HAGICGNN_00687 3.5e-180 exuR K transcriptional
HAGICGNN_00688 4.9e-219 exuT G Sugar (and other) transporter
HAGICGNN_00689 5.8e-144 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_00690 3.8e-204 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HAGICGNN_00691 6.5e-182 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HAGICGNN_00692 2.9e-174 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HAGICGNN_00693 3e-246 yjmB G symporter YjmB
HAGICGNN_00694 3.8e-273 uxaC 5.3.1.12 G glucuronate isomerase
HAGICGNN_00695 1.1e-217 yjlD 1.6.99.3 C NADH dehydrogenase
HAGICGNN_00696 5.9e-65 yjlC S Protein of unknown function (DUF1641)
HAGICGNN_00697 5.6e-66 G Transmembrane secretion effector
HAGICGNN_00698 1.7e-55 rrmJ 2.1.1.226, 2.1.1.227 J Methyltransferase
HAGICGNN_00699 0.0 srfAB Q cog cog1020
HAGICGNN_00700 0.0 srfAB Q Non-ribosomal peptide synthetase modules and related proteins
HAGICGNN_00701 0.0 srfAB Q Non-ribosomal peptide synthetase modules and related proteins
HAGICGNN_00702 3.2e-41 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HAGICGNN_00703 2.1e-74 yjlB S Cupin domain
HAGICGNN_00704 7.1e-170 yjlA EG Putative multidrug resistance efflux transporter
HAGICGNN_00705 7.5e-127 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HAGICGNN_00706 3.4e-119 ybbM S transport system, permease component
HAGICGNN_00707 4.9e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HAGICGNN_00708 2.6e-28
HAGICGNN_00709 5e-202 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HAGICGNN_00710 4.3e-217 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HAGICGNN_00712 4.5e-101 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HAGICGNN_00713 1.1e-06 S Domain of unknown function (DUF4352)
HAGICGNN_00714 2.4e-93 yjgD S Protein of unknown function (DUF1641)
HAGICGNN_00715 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HAGICGNN_00716 1.3e-94 yjgB S Domain of unknown function (DUF4309)
HAGICGNN_00717 7.8e-147 yjfC O Predicted Zn-dependent protease (DUF2268)
HAGICGNN_00718 1.2e-19 yjfB S Putative motility protein
HAGICGNN_00719 2.2e-79 S Protein of unknown function (DUF2690)
HAGICGNN_00720 3.8e-249 xynD 3.5.1.104 G Polysaccharide deacetylase
HAGICGNN_00722 1.4e-162 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HAGICGNN_00723 2.3e-43 yjdJ S Domain of unknown function (DUF4306)
HAGICGNN_00724 1.9e-26 S Domain of unknown function (DUF4177)
HAGICGNN_00725 2.2e-71 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HAGICGNN_00727 5.2e-71 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HAGICGNN_00728 9.5e-39 yjdF S Protein of unknown function (DUF2992)
HAGICGNN_00730 3.7e-163 manA 5.3.1.8 G mannose-6-phosphate isomerase
HAGICGNN_00731 1.5e-307 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HAGICGNN_00732 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HAGICGNN_00733 3.3e-47 yjcN
HAGICGNN_00735 5.7e-41 yjcS S Antibiotic biosynthesis monooxygenase
HAGICGNN_00736 8.8e-167 S response regulator aspartate phosphatase
HAGICGNN_00739 2.4e-204 yjcL S Protein of unknown function (DUF819)
HAGICGNN_00740 3.9e-93 rimJ 2.3.1.128 J Alanine acetyltransferase
HAGICGNN_00741 1.7e-213 metC 2.5.1.48, 4.4.1.8 E cystathionine
HAGICGNN_00742 1.8e-212 metB 2.5.1.48, 4.4.1.8 E cystathionine
HAGICGNN_00743 2.7e-134 yjcH P COG2382 Enterochelin esterase and related enzymes
HAGICGNN_00744 1.6e-91 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HAGICGNN_00745 8.9e-69 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_00746 5.3e-46
HAGICGNN_00747 7.1e-29
HAGICGNN_00748 0.0 yjcD 3.6.4.12 L DNA helicase
HAGICGNN_00749 1.4e-37 spoVIF S Stage VI sporulation protein F
HAGICGNN_00752 2.4e-54 yjcA S Protein of unknown function (DUF1360)
HAGICGNN_00753 6.3e-53 cotV S Spore Coat Protein X and V domain
HAGICGNN_00754 7.9e-25 cotW
HAGICGNN_00755 4e-71 cotX S Spore Coat Protein X and V domain
HAGICGNN_00756 2.9e-95 cotY S Spore coat protein Z
HAGICGNN_00757 2.5e-77 cotZ S Spore coat protein
HAGICGNN_00758 1.6e-38 yjbX S Spore coat protein
HAGICGNN_00759 3.6e-140 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HAGICGNN_00760 2.8e-143 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HAGICGNN_00761 8.7e-179 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HAGICGNN_00762 2.6e-127 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HAGICGNN_00763 2.2e-28 thiS H thiamine diphosphate biosynthetic process
HAGICGNN_00764 1.8e-201 thiO 1.4.3.19 E Glycine oxidase
HAGICGNN_00765 2.6e-101 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HAGICGNN_00766 2.5e-132 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HAGICGNN_00767 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HAGICGNN_00768 2.9e-123 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HAGICGNN_00769 1.2e-144 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAGICGNN_00770 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAGICGNN_00771 5.8e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HAGICGNN_00772 4.3e-59 yjbL S Belongs to the UPF0738 family
HAGICGNN_00773 1.1e-96 yjbK S protein conserved in bacteria
HAGICGNN_00774 8.8e-96 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HAGICGNN_00775 4.1e-71 yjbI S Bacterial-like globin
HAGICGNN_00776 1.3e-165 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HAGICGNN_00777 7.5e-19
HAGICGNN_00778 0.0 pepF E oligoendopeptidase F
HAGICGNN_00779 7.1e-185 yjbF S Competence protein
HAGICGNN_00780 2.9e-114 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HAGICGNN_00781 6.2e-109 yjbE P Integral membrane protein TerC family
HAGICGNN_00782 1e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HAGICGNN_00783 3.8e-102 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_00784 3.1e-177 yjbB EGP Major Facilitator Superfamily
HAGICGNN_00785 7.9e-171 oppF E Belongs to the ABC transporter superfamily
HAGICGNN_00786 2.8e-196 oppD P Belongs to the ABC transporter superfamily
HAGICGNN_00787 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00788 1e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00789 2.3e-311 oppA E ABC transporter substrate-binding protein
HAGICGNN_00790 4.8e-182 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HAGICGNN_00791 1.9e-146 yjbA S Belongs to the UPF0736 family
HAGICGNN_00792 3.7e-160 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00793 8.8e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HAGICGNN_00794 4.8e-288 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HAGICGNN_00795 1.8e-184 appF E Belongs to the ABC transporter superfamily
HAGICGNN_00796 3.3e-183 appD P Belongs to the ABC transporter superfamily
HAGICGNN_00797 2.2e-137 yjaZ O Zn-dependent protease
HAGICGNN_00798 1.2e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HAGICGNN_00799 1.6e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAGICGNN_00800 8.7e-23 yjzB
HAGICGNN_00801 2.3e-24 comZ S ComZ
HAGICGNN_00802 1.1e-178 med S Transcriptional activator protein med
HAGICGNN_00803 3.4e-92 yjaV
HAGICGNN_00804 1.9e-135 yjaU I carboxylic ester hydrolase activity
HAGICGNN_00805 3e-16 yjzD S Protein of unknown function (DUF2929)
HAGICGNN_00806 9.5e-28 yjzC S YjzC-like protein
HAGICGNN_00807 1.6e-166 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HAGICGNN_00808 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HAGICGNN_00809 8.5e-201 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HAGICGNN_00810 1.1e-209 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HAGICGNN_00811 5.2e-131 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HAGICGNN_00812 4.1e-223 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HAGICGNN_00813 4.3e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HAGICGNN_00814 1.2e-89 norB G Major Facilitator Superfamily
HAGICGNN_00815 7.8e-258 yitY C D-arabinono-1,4-lactone oxidase
HAGICGNN_00816 9.7e-22 pilT S Proteolipid membrane potential modulator
HAGICGNN_00817 8e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HAGICGNN_00818 5.7e-138 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HAGICGNN_00819 2.8e-151 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HAGICGNN_00821 3.4e-26 S Protein of unknown function (DUF3813)
HAGICGNN_00822 2.7e-71 ipi S Intracellular proteinase inhibitor
HAGICGNN_00823 4.8e-146 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HAGICGNN_00824 7.7e-152 yitS S protein conserved in bacteria
HAGICGNN_00825 4e-36 yitR S Domain of unknown function (DUF3784)
HAGICGNN_00826 6.7e-156 cvfB S protein conserved in bacteria
HAGICGNN_00827 3.3e-54 yajQ S Belongs to the UPF0234 family
HAGICGNN_00828 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HAGICGNN_00829 1.3e-70 yjcF S Acetyltransferase (GNAT) domain
HAGICGNN_00830 8.6e-127 yitH K Acetyltransferase (GNAT) domain
HAGICGNN_00831 7.7e-225 yitG EGP Major facilitator Superfamily
HAGICGNN_00832 2.7e-205 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HAGICGNN_00833 5.5e-113 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAGICGNN_00834 1.7e-134 yitD 4.4.1.19 S synthase
HAGICGNN_00835 7.6e-110 comB 3.1.3.71 H Belongs to the ComB family
HAGICGNN_00836 5.6e-132 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HAGICGNN_00837 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HAGICGNN_00838 2.5e-104 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HAGICGNN_00839 1e-145 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAGICGNN_00840 7.8e-32 mcbG S Pentapeptide repeats (9 copies)
HAGICGNN_00841 4.8e-255 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_00842 1.8e-94 argO S Lysine exporter protein LysE YggA
HAGICGNN_00843 1e-82 yisT S DinB family
HAGICGNN_00844 2.9e-190 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HAGICGNN_00845 1.4e-85 J Acetyltransferase (GNAT) domain
HAGICGNN_00846 1e-174 purR K helix_turn _helix lactose operon repressor
HAGICGNN_00847 2.3e-159 yisR K Transcriptional regulator
HAGICGNN_00848 8.3e-241 yisQ V Mate efflux family protein
HAGICGNN_00849 4.9e-129 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HAGICGNN_00850 1.6e-85 yizA S Damage-inducible protein DinB
HAGICGNN_00851 0.0 asnO 6.3.5.4 E Asparagine synthase
HAGICGNN_00852 9.9e-92 yisN S Protein of unknown function (DUF2777)
HAGICGNN_00853 0.0 wprA O Belongs to the peptidase S8 family
HAGICGNN_00854 8.1e-55 yisL S UPF0344 protein
HAGICGNN_00855 8.7e-170 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HAGICGNN_00856 1.2e-139 cotH M Spore Coat
HAGICGNN_00857 3.6e-16 yisI S Spo0E like sporulation regulatory protein
HAGICGNN_00858 1.9e-33 gerPA S Spore germination protein
HAGICGNN_00859 1.7e-32 gerPB S cell differentiation
HAGICGNN_00860 1.1e-51 gerPC S Spore germination protein
HAGICGNN_00861 3.1e-23 gerPD S Spore germination protein
HAGICGNN_00862 1.7e-61 gerPE S Spore germination protein GerPE
HAGICGNN_00863 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HAGICGNN_00864 1.3e-48 yisB V COG1403 Restriction endonuclease
HAGICGNN_00865 0.0 sbcC L COG0419 ATPase involved in DNA repair
HAGICGNN_00866 2.3e-215 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HAGICGNN_00867 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HAGICGNN_00868 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HAGICGNN_00869 5.8e-71 yhjR S Rubrerythrin
HAGICGNN_00870 4.2e-298 S Sugar transport-related sRNA regulator N-term
HAGICGNN_00871 4.8e-192 EGP Transmembrane secretion effector
HAGICGNN_00872 9.3e-193 abrB S membrane
HAGICGNN_00873 2.4e-181 yhjM 5.1.1.1 K Transcriptional regulator
HAGICGNN_00874 8.9e-240 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HAGICGNN_00875 4.6e-157 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HAGICGNN_00876 1.3e-190 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HAGICGNN_00877 5.9e-206 glcP G Major Facilitator Superfamily
HAGICGNN_00879 2e-89 yhjH K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_00880 6e-253 yhjG CH FAD binding domain
HAGICGNN_00881 3.6e-88 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HAGICGNN_00882 9.4e-107 yhjE S SNARE associated Golgi protein
HAGICGNN_00883 1.5e-51 yhjD
HAGICGNN_00884 2.6e-26 yhjC S Protein of unknown function (DUF3311)
HAGICGNN_00885 2.3e-257 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAGICGNN_00886 1.1e-40 yhjA S Excalibur calcium-binding domain
HAGICGNN_00887 3.6e-160 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_00888 2.5e-106 comK K Competence transcription factor
HAGICGNN_00889 8.3e-32 yhzC S IDEAL
HAGICGNN_00890 3.1e-153 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_00891 1.3e-287 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HAGICGNN_00892 1.4e-176 hemAT NT chemotaxis protein
HAGICGNN_00893 1.3e-86 bioY S BioY family
HAGICGNN_00894 2.3e-241 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HAGICGNN_00895 1e-185 vraB 2.3.1.9 I Belongs to the thiolase family
HAGICGNN_00896 3.7e-105 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HAGICGNN_00897 2.3e-152 yfmC M Periplasmic binding protein
HAGICGNN_00898 1.4e-176 yhfP 1.1.1.1 C Quinone oxidoreductase
HAGICGNN_00899 4.4e-66 VY92_01935 K acetyltransferase
HAGICGNN_00900 4.4e-195 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HAGICGNN_00901 5.1e-232 yhfN 3.4.24.84 O Peptidase M48
HAGICGNN_00902 3.1e-63 yhfM
HAGICGNN_00903 6.6e-287 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HAGICGNN_00904 9.7e-107 yhfK GM NmrA-like family
HAGICGNN_00905 3.4e-183 lplJ 6.3.1.20 H Lipoate-protein ligase
HAGICGNN_00906 9.3e-138 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HAGICGNN_00907 1.4e-221 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAGICGNN_00908 1.6e-67 3.4.13.21 S ASCH
HAGICGNN_00909 2e-194 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HAGICGNN_00910 7.3e-125 yhfC S Putative membrane peptidase family (DUF2324)
HAGICGNN_00911 4.1e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HAGICGNN_00912 1.1e-216 yhgE S YhgE Pip N-terminal domain protein
HAGICGNN_00913 1.9e-98 yhgD K Transcriptional regulator
HAGICGNN_00914 1.4e-262 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HAGICGNN_00915 3.7e-176 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HAGICGNN_00916 1.1e-197 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HAGICGNN_00917 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HAGICGNN_00918 3.3e-86 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HAGICGNN_00919 1.2e-33 1.15.1.2 C Rubrerythrin
HAGICGNN_00920 4.5e-234 yhfA C membrane
HAGICGNN_00921 3e-218 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HAGICGNN_00922 4.1e-106 ecsC S EcsC protein family
HAGICGNN_00923 2.7e-198 ecsB U ABC transporter
HAGICGNN_00924 3.3e-135 ecsA V transporter (ATP-binding protein)
HAGICGNN_00925 5.2e-80 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HAGICGNN_00926 3.1e-198 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HAGICGNN_00927 8.4e-77 trpP S Tryptophan transporter TrpP
HAGICGNN_00928 5.6e-20
HAGICGNN_00929 3.8e-36 yhaH S YtxH-like protein
HAGICGNN_00930 2.9e-113 hpr K Negative regulator of protease production and sporulation
HAGICGNN_00931 3e-51 yhaI S Protein of unknown function (DUF1878)
HAGICGNN_00932 2.1e-88 yhaK S Putative zincin peptidase
HAGICGNN_00933 6.8e-111 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HAGICGNN_00934 5.6e-19 yhaL S Sporulation protein YhaL
HAGICGNN_00935 1e-176 yhaM L Shows a 3'-5' exoribonuclease activity
HAGICGNN_00936 0.0 yhaN L AAA domain
HAGICGNN_00937 5.9e-214 yhaO L DNA repair exonuclease
HAGICGNN_00938 1.4e-200 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HAGICGNN_00939 8.6e-162 yhaQ S ABC transporter, ATP-binding protein
HAGICGNN_00940 4.3e-23 S YhzD-like protein
HAGICGNN_00941 6.5e-126 yhaR 5.3.3.18 I enoyl-CoA hydratase
HAGICGNN_00943 2.1e-85 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HAGICGNN_00944 1e-205 yhaU P COG0475 Kef-type K transport systems, membrane components
HAGICGNN_00945 6.7e-284 hemZ H coproporphyrinogen III oxidase
HAGICGNN_00946 2.6e-155 yhaX S haloacid dehalogenase-like hydrolase
HAGICGNN_00947 8.7e-183 yhaZ L DNA alkylation repair enzyme
HAGICGNN_00948 1.2e-47 yheA S Belongs to the UPF0342 family
HAGICGNN_00949 3.8e-191 yheB S Belongs to the UPF0754 family
HAGICGNN_00950 7.1e-211 yheC HJ YheC/D like ATP-grasp
HAGICGNN_00951 1.7e-254 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HAGICGNN_00952 7.2e-35 yheE S Family of unknown function (DUF5342)
HAGICGNN_00953 2.4e-27 sspB S spore protein
HAGICGNN_00955 1.1e-96 yheG GM NAD(P)H-binding
HAGICGNN_00956 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HAGICGNN_00957 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HAGICGNN_00958 3.4e-83 nhaX T Belongs to the universal stress protein A family
HAGICGNN_00959 1.8e-219 nhaC C Na H antiporter
HAGICGNN_00960 6.7e-148 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HAGICGNN_00961 4.6e-133 yheN G deacetylase
HAGICGNN_00962 9.4e-130 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HAGICGNN_00963 1.4e-198 yhdY M Mechanosensitive ion channel
HAGICGNN_00965 1.2e-126 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HAGICGNN_00966 1.4e-55 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAGICGNN_00967 2.2e-39 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HAGICGNN_00968 8.4e-233 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HAGICGNN_00969 1.8e-215 yhdR 2.6.1.1 E Aminotransferase
HAGICGNN_00970 8.9e-69 cueR K transcriptional
HAGICGNN_00971 1.4e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HAGICGNN_00972 1.1e-164 galE 5.1.3.2 GM GDP-mannose 4,6 dehydratase
HAGICGNN_00973 3.3e-171 dadA 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HAGICGNN_00974 1.5e-106 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HAGICGNN_00975 2.7e-180 yhdN C Aldo keto reductase
HAGICGNN_00976 1.2e-85 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_00977 2.1e-194 yhdL S Sigma factor regulator N-terminal
HAGICGNN_00978 8.1e-45 yhdK S Sigma-M inhibitor protein
HAGICGNN_00979 7e-69 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_00980 1.6e-231 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_00981 3.3e-234 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAGICGNN_00982 2.7e-247 yhdG E amino acid
HAGICGNN_00983 4.9e-154 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_00984 4.4e-200 citA 2.3.3.1 C Belongs to the citrate synthase family
HAGICGNN_00985 1.7e-159 citR K Transcriptional regulator
HAGICGNN_00986 1.5e-135 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HAGICGNN_00987 1e-246 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HAGICGNN_00988 1.1e-272 ycgB S Stage V sporulation protein R
HAGICGNN_00989 1.9e-230 ygxB M Conserved TM helix
HAGICGNN_00990 1.1e-74 nsrR K Transcriptional regulator
HAGICGNN_00991 2.5e-171 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HAGICGNN_00992 2.1e-49 yhdC S Protein of unknown function (DUF3889)
HAGICGNN_00993 2.8e-38 yhdB S YhdB-like protein
HAGICGNN_00994 6.3e-80 azr 1.7.1.6 S NADPH-dependent FMN reductase
HAGICGNN_00995 1.6e-104 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_00996 5.6e-198 yhcY 2.7.13.3 T Histidine kinase
HAGICGNN_00997 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HAGICGNN_00998 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HAGICGNN_00999 2e-288 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HAGICGNN_01000 4.8e-151 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HAGICGNN_01001 2.6e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HAGICGNN_01002 5.2e-256 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAGICGNN_01003 2.2e-82 mepB S MepB protein
HAGICGNN_01004 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HAGICGNN_01005 2.5e-118 yhcW 5.4.2.6 S hydrolase
HAGICGNN_01006 1.4e-66 yhcV S COG0517 FOG CBS domain
HAGICGNN_01007 3.6e-64 yhcU S Family of unknown function (DUF5365)
HAGICGNN_01008 1.1e-159 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HAGICGNN_01009 3.4e-98 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HAGICGNN_01010 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HAGICGNN_01011 3.2e-97 yhcQ M Spore coat protein
HAGICGNN_01012 1.9e-151 yhcP
HAGICGNN_01013 4.6e-63 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAGICGNN_01014 5.6e-37 yhcM
HAGICGNN_01015 1.1e-211 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAGICGNN_01016 4.5e-181 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HAGICGNN_01017 3.3e-139 metQ M Belongs to the nlpA lipoprotein family
HAGICGNN_01018 1e-30 cspB K Cold-shock protein
HAGICGNN_01019 4.8e-155 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAGICGNN_01020 6.5e-157 yhcH V ABC transporter, ATP-binding protein
HAGICGNN_01021 3e-114 yhcG V ABC transporter, ATP-binding protein
HAGICGNN_01022 3.3e-59 yhcF K Transcriptional regulator
HAGICGNN_01023 1.9e-53
HAGICGNN_01024 1.6e-32 yhcC
HAGICGNN_01025 2.8e-96 yhcB 1.6.5.2 S Belongs to the WrbA family
HAGICGNN_01026 3e-282 yhcA EGP Major facilitator Superfamily
HAGICGNN_01027 4.7e-90 yhbJ V COG1566 Multidrug resistance efflux pump
HAGICGNN_01028 1e-73 yhbI K DNA-binding transcription factor activity
HAGICGNN_01029 7.9e-224 yhbH S Belongs to the UPF0229 family
HAGICGNN_01030 0.0 prkA T Ser protein kinase
HAGICGNN_01031 1.6e-57 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HAGICGNN_01032 9.8e-60 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HAGICGNN_01033 1.1e-117 yhbD K Protein of unknown function (DUF4004)
HAGICGNN_01034 5.9e-85 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HAGICGNN_01035 1.2e-166 yhbB S Putative amidase domain
HAGICGNN_01036 2.5e-222 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HAGICGNN_01037 2.1e-106 yhzB S B3/4 domain
HAGICGNN_01039 4.4e-29 K Transcriptional regulator
HAGICGNN_01040 3e-73 ygaO
HAGICGNN_01041 6.6e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAGICGNN_01044 6.7e-212 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HAGICGNN_01045 2.5e-139 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HAGICGNN_01046 1.1e-162 ssuA M Sulfonate ABC transporter
HAGICGNN_01047 3.2e-133 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HAGICGNN_01048 3.6e-287 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HAGICGNN_01050 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HAGICGNN_01051 1.2e-34 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HAGICGNN_01053 1.7e-25
HAGICGNN_01054 4.4e-138 spo0M S COG4326 Sporulation control protein
HAGICGNN_01058 2e-08
HAGICGNN_01066 7.8e-08
HAGICGNN_01071 1.2e-186 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HAGICGNN_01072 1.1e-141 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HAGICGNN_01074 3.7e-117 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HAGICGNN_01075 2.4e-119 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HAGICGNN_01076 3.2e-168 spoIID D Stage II sporulation protein D
HAGICGNN_01077 2.3e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAGICGNN_01078 1.6e-129 ywmB S TATA-box binding
HAGICGNN_01079 1.3e-32 ywzB S membrane
HAGICGNN_01080 7.2e-83 ywmA
HAGICGNN_01081 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HAGICGNN_01082 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HAGICGNN_01083 9.5e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HAGICGNN_01084 5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HAGICGNN_01085 3.4e-84 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAGICGNN_01086 2.1e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HAGICGNN_01087 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HAGICGNN_01088 6.6e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HAGICGNN_01089 3.7e-61 atpI S ATP synthase
HAGICGNN_01090 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HAGICGNN_01091 3e-237 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HAGICGNN_01092 2.6e-89 ywlG S Belongs to the UPF0340 family
HAGICGNN_01093 2.2e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HAGICGNN_01094 2e-74 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAGICGNN_01095 2.1e-89 mntP P Probably functions as a manganese efflux pump
HAGICGNN_01096 4.7e-188 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HAGICGNN_01097 1.6e-71 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HAGICGNN_01098 1.3e-106 spoIIR S stage II sporulation protein R
HAGICGNN_01099 5.9e-53 ywlA S Uncharacterised protein family (UPF0715)
HAGICGNN_01101 4.6e-152 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HAGICGNN_01102 1.6e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HAGICGNN_01103 1.2e-64 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAGICGNN_01104 4e-85 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HAGICGNN_01105 8e-158 ywkB S Membrane transport protein
HAGICGNN_01106 0.0 sfcA 1.1.1.38 C malic enzyme
HAGICGNN_01107 5.5e-101 tdk 2.7.1.21 F thymidine kinase
HAGICGNN_01108 1.1e-32 rpmE J Binds the 23S rRNA
HAGICGNN_01109 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HAGICGNN_01110 8.9e-173 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HAGICGNN_01111 4.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HAGICGNN_01112 3.8e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HAGICGNN_01113 1.4e-156 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HAGICGNN_01114 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HAGICGNN_01115 1.1e-89 ywjG S Domain of unknown function (DUF2529)
HAGICGNN_01116 2e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HAGICGNN_01117 2.7e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HAGICGNN_01118 3.1e-201 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HAGICGNN_01119 0.0 fadF C COG0247 Fe-S oxidoreductase
HAGICGNN_01120 3.5e-203 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HAGICGNN_01121 3.9e-176 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HAGICGNN_01122 1.8e-41 ywjC
HAGICGNN_01123 6.9e-87 ywjB H RibD C-terminal domain
HAGICGNN_01124 0.0 ywjA V ABC transporter
HAGICGNN_01125 3.5e-277 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAGICGNN_01126 3e-97 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAGICGNN_01127 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
HAGICGNN_01128 1.3e-88 narJ 1.7.5.1 C nitrate reductase
HAGICGNN_01129 9.7e-296 narH 1.7.5.1 C Nitrate reductase, beta
HAGICGNN_01130 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAGICGNN_01131 8.8e-81 arfM T cyclic nucleotide binding
HAGICGNN_01132 1.5e-129 ywiC S YwiC-like protein
HAGICGNN_01133 2.1e-126 fnr K helix_turn_helix, cAMP Regulatory protein
HAGICGNN_01134 7.8e-211 narK P COG2223 Nitrate nitrite transporter
HAGICGNN_01135 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HAGICGNN_01136 2e-71 ywiB S protein conserved in bacteria
HAGICGNN_01137 1e-07 S Bacteriocin subtilosin A
HAGICGNN_01138 8.7e-267 C Fe-S oxidoreductases
HAGICGNN_01140 2.7e-126 cbiO V ABC transporter
HAGICGNN_01141 2.7e-225 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HAGICGNN_01142 3.3e-193 2.7.1.26, 2.7.7.2 L Peptidase, M16
HAGICGNN_01143 1.9e-218 L Peptidase, M16
HAGICGNN_01145 9.3e-200 ywhL CO amine dehydrogenase activity
HAGICGNN_01146 1.1e-184 ywhK CO amine dehydrogenase activity
HAGICGNN_01147 1.7e-85 S aspartate phosphatase
HAGICGNN_01149 1.1e-166 speB 3.5.3.11 E Belongs to the arginase family
HAGICGNN_01150 5.3e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HAGICGNN_01151 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HAGICGNN_01152 3e-64
HAGICGNN_01153 4.9e-93 ywhD S YwhD family
HAGICGNN_01154 8.1e-117 ywhC S Peptidase family M50
HAGICGNN_01155 1.3e-24 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HAGICGNN_01156 8.9e-69 ywhA K Transcriptional regulator
HAGICGNN_01157 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAGICGNN_01158 2.1e-223 mmr U Major Facilitator Superfamily
HAGICGNN_01159 4.7e-74 yffB K Transcriptional regulator
HAGICGNN_01160 1.3e-87 ywgA 2.1.1.72, 3.1.21.3
HAGICGNN_01161 9e-253 ywfO S COG1078 HD superfamily phosphohydrolases
HAGICGNN_01162 3.1e-36 ywzC S Belongs to the UPF0741 family
HAGICGNN_01163 3.8e-105 rsfA_1
HAGICGNN_01164 1.4e-148 ywfM EG EamA-like transporter family
HAGICGNN_01165 3.8e-151 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HAGICGNN_01166 1.2e-152 cysL K Transcriptional regulator
HAGICGNN_01167 2.1e-174 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HAGICGNN_01168 4.3e-146 ywfI C May function as heme-dependent peroxidase
HAGICGNN_01169 6.2e-132 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_01170 4e-223 ywfG 2.6.1.83 E Aminotransferase class I and II
HAGICGNN_01171 1.1e-204 bacE EGP Major facilitator Superfamily
HAGICGNN_01172 1.2e-263 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HAGICGNN_01173 1.6e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_01174 1.2e-134 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HAGICGNN_01175 4.1e-107 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HAGICGNN_01176 6e-190 ywfA EGP Major facilitator Superfamily
HAGICGNN_01177 4.4e-291 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HAGICGNN_01178 7.7e-241 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HAGICGNN_01179 2.4e-75
HAGICGNN_01180 1.3e-84 spsL 5.1.3.13 M Spore Coat
HAGICGNN_01181 3.2e-150 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HAGICGNN_01182 4.5e-177 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HAGICGNN_01183 7.4e-135 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HAGICGNN_01184 2.1e-164 spsG M Spore Coat
HAGICGNN_01185 2.9e-120 spsF M Spore Coat
HAGICGNN_01186 1.1e-206 spsE 2.5.1.56 M acid synthase
HAGICGNN_01187 2e-155 spsD 2.3.1.210 K Spore Coat
HAGICGNN_01188 7.9e-216 spsC E Belongs to the DegT DnrJ EryC1 family
HAGICGNN_01189 5.4e-259 spsB M Capsule polysaccharide biosynthesis protein
HAGICGNN_01190 3.6e-140 spsA M Spore Coat
HAGICGNN_01191 3.5e-70 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HAGICGNN_01192 9.7e-59 ywdK S small membrane protein
HAGICGNN_01193 5.8e-231 ywdJ F Xanthine uracil
HAGICGNN_01194 1.4e-45 ywdI S Family of unknown function (DUF5327)
HAGICGNN_01195 6.3e-257 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HAGICGNN_01196 3e-127 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HAGICGNN_01197 3.4e-149 ywdF GT2,GT4 S Glycosyltransferase like family 2
HAGICGNN_01198 8.7e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HAGICGNN_01199 1.4e-75 ctsR K Belongs to the CtsR family
HAGICGNN_01200 1.7e-57 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HAGICGNN_01201 4.8e-199 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HAGICGNN_01202 0.0 clpC O Belongs to the ClpA ClpB family
HAGICGNN_01203 4e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HAGICGNN_01204 1.4e-195 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HAGICGNN_01205 7.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HAGICGNN_01206 2.2e-120 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HAGICGNN_01207 5.9e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HAGICGNN_01208 4.5e-277 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HAGICGNN_01209 2.1e-117 cysE 2.3.1.30 E Serine acetyltransferase
HAGICGNN_01210 7.1e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAGICGNN_01211 2.6e-71 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HAGICGNN_01212 8.3e-134 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAGICGNN_01213 4.7e-88 yacP S RNA-binding protein containing a PIN domain
HAGICGNN_01214 4.4e-115 sigH K Belongs to the sigma-70 factor family
HAGICGNN_01215 5.2e-18 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HAGICGNN_01216 1.4e-95 nusG K Participates in transcription elongation, termination and antitermination
HAGICGNN_01217 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HAGICGNN_01218 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HAGICGNN_01219 1.5e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HAGICGNN_01220 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HAGICGNN_01221 2.2e-105 rsmC 2.1.1.172 J Methyltransferase
HAGICGNN_01222 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAGICGNN_01223 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAGICGNN_01224 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HAGICGNN_01225 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HAGICGNN_01226 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HAGICGNN_01227 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HAGICGNN_01228 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HAGICGNN_01229 6.8e-157 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HAGICGNN_01230 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HAGICGNN_01231 1.8e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HAGICGNN_01232 3e-105 rplD J Forms part of the polypeptide exit tunnel
HAGICGNN_01233 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HAGICGNN_01234 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HAGICGNN_01235 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HAGICGNN_01236 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HAGICGNN_01237 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HAGICGNN_01238 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HAGICGNN_01239 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HAGICGNN_01240 4.6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HAGICGNN_01241 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HAGICGNN_01242 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HAGICGNN_01243 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HAGICGNN_01244 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HAGICGNN_01245 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HAGICGNN_01246 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HAGICGNN_01247 2.6e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HAGICGNN_01248 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HAGICGNN_01249 1.9e-23 rpmD J Ribosomal protein L30
HAGICGNN_01250 6.9e-72 rplO J binds to the 23S rRNA
HAGICGNN_01251 3e-232 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HAGICGNN_01252 2.2e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HAGICGNN_01253 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HAGICGNN_01254 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HAGICGNN_01255 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HAGICGNN_01256 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HAGICGNN_01257 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HAGICGNN_01258 9e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HAGICGNN_01259 3.6e-58 rplQ J Ribosomal protein L17
HAGICGNN_01260 6.2e-154 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAGICGNN_01261 1.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAGICGNN_01262 1.6e-122 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HAGICGNN_01263 1e-139 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HAGICGNN_01264 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HAGICGNN_01265 8.1e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HAGICGNN_01266 1.8e-136 ybaJ Q Methyltransferase domain
HAGICGNN_01267 2.8e-65 ybaK S Protein of unknown function (DUF2521)
HAGICGNN_01268 2.1e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HAGICGNN_01269 1.1e-195 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HAGICGNN_01270 7.6e-84 gerD
HAGICGNN_01271 1.4e-99 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HAGICGNN_01272 2.8e-137 pdaB 3.5.1.104 G Polysaccharide deacetylase
HAGICGNN_01273 8.4e-30 csfB S Inhibitor of sigma-G Gin
HAGICGNN_01274 1.5e-96 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HAGICGNN_01275 8.7e-191 yaaN P Belongs to the TelA family
HAGICGNN_01276 2e-253 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HAGICGNN_01277 2.5e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HAGICGNN_01278 8.3e-54 yaaQ S protein conserved in bacteria
HAGICGNN_01279 1.4e-69 yaaR S protein conserved in bacteria
HAGICGNN_01280 2.5e-175 holB 2.7.7.7 L DNA polymerase III
HAGICGNN_01281 1.7e-143 yaaT S stage 0 sporulation protein
HAGICGNN_01282 4.8e-31 yabA L Involved in initiation control of chromosome replication
HAGICGNN_01283 4.4e-135 yabB 2.1.1.223 S Conserved hypothetical protein 95
HAGICGNN_01284 3.1e-47 yazA L endonuclease containing a URI domain
HAGICGNN_01285 5.1e-143 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HAGICGNN_01286 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HAGICGNN_01287 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HAGICGNN_01288 2.5e-141 tatD L hydrolase, TatD
HAGICGNN_01289 7.8e-180 rpfB GH23 T protein conserved in bacteria
HAGICGNN_01290 5.7e-95 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HAGICGNN_01291 1.6e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HAGICGNN_01292 5.2e-135 yabG S peptidase
HAGICGNN_01293 7.8e-39 veg S protein conserved in bacteria
HAGICGNN_01294 1.9e-26 sspF S DNA topological change
HAGICGNN_01295 2.8e-157 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HAGICGNN_01296 5e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HAGICGNN_01297 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HAGICGNN_01298 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HAGICGNN_01299 8.4e-10 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HAGICGNN_01300 2.6e-226 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HAGICGNN_01301 1e-173 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HAGICGNN_01302 3.4e-93 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HAGICGNN_01303 1.5e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HAGICGNN_01304 5.8e-38 yabK S Peptide ABC transporter permease
HAGICGNN_01305 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HAGICGNN_01306 1.5e-92 spoVT K stage V sporulation protein
HAGICGNN_01307 2.5e-265 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_01308 7.3e-235 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HAGICGNN_01309 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HAGICGNN_01310 1.5e-49 yabP S Sporulation protein YabP
HAGICGNN_01311 2.2e-103 yabQ S spore cortex biosynthesis protein
HAGICGNN_01312 1.1e-44 divIC D Septum formation initiator
HAGICGNN_01313 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HAGICGNN_01316 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HAGICGNN_01317 4.9e-123 yabS S protein containing a von Willebrand factor type A (vWA) domain
HAGICGNN_01318 8.2e-177 KLT serine threonine protein kinase
HAGICGNN_01319 9.4e-264 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HAGICGNN_01320 6.7e-93 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HAGICGNN_01321 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HAGICGNN_01322 4.4e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HAGICGNN_01323 1.1e-161 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HAGICGNN_01324 2.7e-155 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HAGICGNN_01325 2.2e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HAGICGNN_01326 3.8e-257 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAGICGNN_01327 2.1e-105 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HAGICGNN_01328 7.7e-155 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HAGICGNN_01329 1e-156 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HAGICGNN_01330 1e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HAGICGNN_01331 2.2e-82 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HAGICGNN_01332 1.5e-29 yazB K transcriptional
HAGICGNN_01333 6.2e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAGICGNN_01334 4.6e-285 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HAGICGNN_01335 7.8e-08
HAGICGNN_01337 4.6e-161 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HAGICGNN_01338 1.1e-83 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HAGICGNN_01339 2.2e-117 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HAGICGNN_01340 7.6e-82 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HAGICGNN_01341 7.6e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HAGICGNN_01342 3.2e-307 ydiF S ABC transporter
HAGICGNN_01343 1.6e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HAGICGNN_01344 1.1e-115 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HAGICGNN_01345 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HAGICGNN_01346 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAGICGNN_01347 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HAGICGNN_01348 3.2e-122 ydiL S CAAX protease self-immunity
HAGICGNN_01349 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HAGICGNN_01350 1.6e-278 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HAGICGNN_01352 1.1e-40
HAGICGNN_01353 2e-237 yobL S Bacterial EndoU nuclease
HAGICGNN_01354 2.2e-78 3.1.21.3 V Type I restriction modification DNA specificity domain
HAGICGNN_01355 1.2e-288 hsdM 2.1.1.72 V Type I restriction-modification system
HAGICGNN_01356 4.8e-91 3.1.21.3 V Type I restriction modification DNA specificity domain
HAGICGNN_01357 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
HAGICGNN_01358 0.0 K NB-ARC domain
HAGICGNN_01359 1e-198 gutB 1.1.1.14 E Dehydrogenase
HAGICGNN_01360 2e-242 gutA G MFS/sugar transport protein
HAGICGNN_01361 4.4e-164 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HAGICGNN_01362 1.7e-101 pspA KT Phage shock protein A
HAGICGNN_01363 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HAGICGNN_01364 1.4e-123 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HAGICGNN_01365 4.5e-140 ydjI S virion core protein (lumpy skin disease virus)
HAGICGNN_01366 4.8e-177 S Ion transport 2 domain protein
HAGICGNN_01367 1.6e-250 iolT EGP Major facilitator Superfamily
HAGICGNN_01368 1.4e-192 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HAGICGNN_01369 8.4e-63 ydjM M Lytic transglycolase
HAGICGNN_01370 3.7e-140 ydjN U Involved in the tonB-independent uptake of proteins
HAGICGNN_01371 2.6e-144 yclE 3.4.11.5 S Alpha beta hydrolase
HAGICGNN_01372 5.4e-75 yclD
HAGICGNN_01373 4.4e-38 bsdD 4.1.1.61 S response to toxic substance
HAGICGNN_01374 5e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HAGICGNN_01375 3e-99 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HAGICGNN_01376 2.5e-158 bsdA K LysR substrate binding domain
HAGICGNN_01377 6e-138 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HAGICGNN_01378 3.4e-121 tcyB P COG0765 ABC-type amino acid transport system, permease component
HAGICGNN_01379 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HAGICGNN_01380 3.8e-111 yczE S membrane
HAGICGNN_01381 7.7e-115 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HAGICGNN_01382 4e-240 ycxD K GntR family transcriptional regulator
HAGICGNN_01383 2e-145 ycxC EG EamA-like transporter family
HAGICGNN_01384 5.6e-212 EGP Major Facilitator Superfamily
HAGICGNN_01385 8.9e-133 srfAD Q thioesterase
HAGICGNN_01386 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HAGICGNN_01387 2e-231 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_01388 3.7e-163 yaaC S YaaC-like Protein
HAGICGNN_01389 1.5e-272 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HAGICGNN_01390 3.5e-244 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HAGICGNN_01391 9.1e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HAGICGNN_01392 2.9e-105 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HAGICGNN_01393 6.2e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HAGICGNN_01394 1.3e-09
HAGICGNN_01395 1.1e-118 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HAGICGNN_01396 3.3e-112 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HAGICGNN_01397 2.3e-208 yaaH M Glycoside Hydrolase Family
HAGICGNN_01398 3.3e-92 yaaI Q COG1335 Amidases related to nicotinamidase
HAGICGNN_01399 9.9e-80 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HAGICGNN_01400 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HAGICGNN_01401 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HAGICGNN_01402 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HAGICGNN_01403 2.3e-31 yaaL S Protein of unknown function (DUF2508)
HAGICGNN_01404 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HAGICGNN_01405 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_01406 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_01407 9.4e-242 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_01408 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_01409 0.0 vpr O Belongs to the peptidase S8 family
HAGICGNN_01411 2.7e-149 sacT K transcriptional antiterminator
HAGICGNN_01412 9.4e-133 focA P Formate/nitrite transporter
HAGICGNN_01413 5.8e-250 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_01414 5.8e-277 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HAGICGNN_01416 4.1e-29 ywdA
HAGICGNN_01417 2e-08
HAGICGNN_01424 1.3e-09
HAGICGNN_01425 7.8e-08
HAGICGNN_01434 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HAGICGNN_01435 5.2e-188 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HAGICGNN_01436 2.8e-172 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HAGICGNN_01437 6.1e-266 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HAGICGNN_01438 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HAGICGNN_01439 6.9e-70 tspO T membrane
HAGICGNN_01440 8.8e-198 cotI S Spore coat protein
HAGICGNN_01441 4.5e-208 cotSA M Glycosyl transferases group 1
HAGICGNN_01442 6.7e-198 cotS S Seems to be required for the assembly of the CotSA protein in spores
HAGICGNN_01444 2.1e-219 ytcC M Glycosyltransferase Family 4
HAGICGNN_01445 2e-169 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HAGICGNN_01446 1e-224 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAGICGNN_01447 2.4e-139 galU 2.7.7.9 M Nucleotidyl transferase
HAGICGNN_01448 2.4e-130 dksA T COG1734 DnaK suppressor protein
HAGICGNN_01449 3.7e-256 menF 5.4.4.2 HQ Isochorismate synthase
HAGICGNN_01450 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HAGICGNN_01451 1.7e-140 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HAGICGNN_01452 3.5e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HAGICGNN_01453 2.2e-260 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HAGICGNN_01454 1.8e-209 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HAGICGNN_01455 3.1e-159 troA P Belongs to the bacterial solute-binding protein 9 family
HAGICGNN_01456 2.7e-132 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HAGICGNN_01457 1.2e-209 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HAGICGNN_01458 1.8e-143 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HAGICGNN_01459 3.3e-24 S Domain of Unknown Function (DUF1540)
HAGICGNN_01460 5.8e-186 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HAGICGNN_01461 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HAGICGNN_01462 3.6e-41 rpmE2 J Ribosomal protein L31
HAGICGNN_01463 3.6e-97 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HAGICGNN_01464 1.3e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HAGICGNN_01465 3.5e-68 ytkA S YtkA-like
HAGICGNN_01467 1e-75 dps P Belongs to the Dps family
HAGICGNN_01468 2e-62 ytkC S Bacteriophage holin family
HAGICGNN_01469 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HAGICGNN_01470 4.6e-138 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HAGICGNN_01471 7.8e-143 ytlC P ABC transporter
HAGICGNN_01472 7.3e-181 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HAGICGNN_01473 7.7e-143 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HAGICGNN_01474 6.1e-38 ytmB S Protein of unknown function (DUF2584)
HAGICGNN_01475 7.2e-305 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HAGICGNN_01476 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HAGICGNN_01477 0.0 asnB 6.3.5.4 E Asparagine synthase
HAGICGNN_01478 1.1e-240 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_01479 2.4e-55 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HAGICGNN_01480 4.9e-145 ytpA 3.1.1.5 I Alpha beta hydrolase
HAGICGNN_01481 2e-208 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HAGICGNN_01482 5e-102 ytqB J Putative rRNA methylase
HAGICGNN_01483 3.7e-187 yhcC S Fe-S oxidoreductase
HAGICGNN_01484 5.1e-41 ytzC S Protein of unknown function (DUF2524)
HAGICGNN_01486 1.8e-63 ytrA K GntR family transcriptional regulator
HAGICGNN_01487 2.1e-160 ytrB P abc transporter atp-binding protein
HAGICGNN_01488 4.6e-140 P ABC-2 family transporter protein
HAGICGNN_01489 1.6e-153
HAGICGNN_01490 4.5e-126 ytrE V ABC transporter, ATP-binding protein
HAGICGNN_01491 5.7e-231 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HAGICGNN_01492 1.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_01493 4.6e-172 T PhoQ Sensor
HAGICGNN_01494 4.5e-135 bceA V ABC transporter, ATP-binding protein
HAGICGNN_01495 0.0 bceB V ABC transporter (permease)
HAGICGNN_01496 5.3e-37 yttA 2.7.13.3 S Pfam Transposase IS66
HAGICGNN_01497 5.2e-207 yttB EGP Major facilitator Superfamily
HAGICGNN_01498 8.4e-137 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HAGICGNN_01499 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HAGICGNN_01500 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HAGICGNN_01501 8.1e-51 ytwF P Sulfurtransferase
HAGICGNN_01502 1.5e-247 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HAGICGNN_01503 1.9e-139 amyC P ABC transporter (permease)
HAGICGNN_01504 1.1e-164 amyD P ABC transporter
HAGICGNN_01505 1.5e-231 msmE G Bacterial extracellular solute-binding protein
HAGICGNN_01506 2.8e-180 msmR K Transcriptional regulator
HAGICGNN_01507 2.9e-157 ytaP S Acetyl xylan esterase (AXE1)
HAGICGNN_01508 3.1e-60 S Psort location CytoplasmicMembrane, score
HAGICGNN_01509 1.1e-133 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HAGICGNN_01510 6.2e-249 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HAGICGNN_01511 7.2e-193 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HAGICGNN_01512 9.4e-116 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HAGICGNN_01513 3.6e-185 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HAGICGNN_01514 1.8e-199 bioI 1.14.14.46 C Cytochrome P450
HAGICGNN_01515 4.2e-133 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HAGICGNN_01516 1.7e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HAGICGNN_01517 2.1e-282 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HAGICGNN_01518 0.0 ytdP K Transcriptional regulator
HAGICGNN_01519 3.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HAGICGNN_01520 3.2e-214 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HAGICGNN_01521 8.1e-62 yteS G transport
HAGICGNN_01522 2e-244 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HAGICGNN_01523 2.1e-104 yteU S Integral membrane protein
HAGICGNN_01524 3.1e-26 yteV S Sporulation protein Cse60
HAGICGNN_01525 7.3e-270 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HAGICGNN_01526 3.5e-233 ytfP S HI0933-like protein
HAGICGNN_01527 7.2e-284 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_01528 1.9e-127 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAGICGNN_01529 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HAGICGNN_01530 3e-125 ythP V ABC transporter
HAGICGNN_01531 9.6e-182 ythQ U Bacterial ABC transporter protein EcsB
HAGICGNN_01532 3.1e-221 pbuO S permease
HAGICGNN_01533 2e-258 pepV 3.5.1.18 E Dipeptidase
HAGICGNN_01534 1.5e-169 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HAGICGNN_01535 7.5e-92 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HAGICGNN_01536 6.9e-159 ytlQ
HAGICGNN_01537 3.5e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HAGICGNN_01538 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HAGICGNN_01539 4.6e-151 ytmP 2.7.1.89 M Phosphotransferase
HAGICGNN_01540 2e-45 ytzH S YtzH-like protein
HAGICGNN_01541 6.4e-119 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HAGICGNN_01542 9.6e-147 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HAGICGNN_01543 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HAGICGNN_01544 4.9e-51 ytzB S small secreted protein
HAGICGNN_01545 8.3e-204 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HAGICGNN_01546 3.8e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HAGICGNN_01547 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HAGICGNN_01548 7.8e-146 ytpQ S Belongs to the UPF0354 family
HAGICGNN_01549 5.9e-106 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAGICGNN_01550 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HAGICGNN_01551 1.7e-251 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HAGICGNN_01552 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HAGICGNN_01553 6.5e-17 ytxH S COG4980 Gas vesicle protein
HAGICGNN_01554 7.7e-52 ytxJ O Protein of unknown function (DUF2847)
HAGICGNN_01555 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HAGICGNN_01556 1.9e-181 ccpA K catabolite control protein A
HAGICGNN_01557 5.3e-142 motA N flagellar motor
HAGICGNN_01558 4e-117 motS N Flagellar motor protein
HAGICGNN_01559 1.1e-214 acuC BQ histone deacetylase
HAGICGNN_01560 5.3e-113 acuB S Domain in cystathionine beta-synthase and other proteins.
HAGICGNN_01561 2.8e-119 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HAGICGNN_01562 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HAGICGNN_01563 2e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAGICGNN_01565 4.8e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HAGICGNN_01566 1.2e-284 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HAGICGNN_01567 2.7e-85 ytsP 1.8.4.14 T GAF domain-containing protein
HAGICGNN_01568 1.2e-106 yttP K Transcriptional regulator
HAGICGNN_01569 2.4e-147 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HAGICGNN_01570 1.3e-262 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HAGICGNN_01571 5e-174 braB E Component of the transport system for branched-chain amino acids
HAGICGNN_01572 9.8e-195 iscS2 2.8.1.7 E Cysteine desulfurase
HAGICGNN_01573 1.8e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HAGICGNN_01574 1.1e-27 sasP S spore protein
HAGICGNN_01575 9.2e-300 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HAGICGNN_01576 1.7e-293 ytcJ S amidohydrolase
HAGICGNN_01577 2e-146 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HAGICGNN_01578 3.1e-176 sppA OU signal peptide peptidase SppA
HAGICGNN_01579 1.9e-81 yteJ S RDD family
HAGICGNN_01580 3.8e-109 ytfI S Protein of unknown function (DUF2953)
HAGICGNN_01581 6.3e-68 ytfJ S Sporulation protein YtfJ
HAGICGNN_01582 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HAGICGNN_01583 5.9e-156 ytxK 2.1.1.72 L DNA methylase
HAGICGNN_01584 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HAGICGNN_01585 1.1e-84 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HAGICGNN_01586 6.7e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HAGICGNN_01587 2.1e-263 argH 4.3.2.1 E argininosuccinate lyase
HAGICGNN_01589 3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_01590 2.1e-128 ytkL S Belongs to the UPF0173 family
HAGICGNN_01591 3.9e-241 ytoI K transcriptional regulator containing CBS domains
HAGICGNN_01592 4.9e-45 ytpI S YtpI-like protein
HAGICGNN_01593 1.7e-181 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HAGICGNN_01594 2e-28
HAGICGNN_01595 4.5e-67 ytrI
HAGICGNN_01596 6e-55 ytrH S Sporulation protein YtrH
HAGICGNN_01597 0.0 dnaE 2.7.7.7 L DNA polymerase
HAGICGNN_01598 4.9e-224 ytsJ 1.1.1.38 C Malate dehydrogenase
HAGICGNN_01599 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HAGICGNN_01600 3.1e-181 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HAGICGNN_01601 3.7e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HAGICGNN_01602 5.5e-306 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HAGICGNN_01603 2.8e-61 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HAGICGNN_01604 3.5e-189 ytvI S sporulation integral membrane protein YtvI
HAGICGNN_01605 5.2e-70 yeaL S membrane
HAGICGNN_01606 3.4e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
HAGICGNN_01607 2e-241 icd 1.1.1.42 C isocitrate
HAGICGNN_01608 6.9e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HAGICGNN_01609 4.5e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_01610 2.9e-310 phoR 2.7.13.3 T Signal transduction histidine kinase
HAGICGNN_01611 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HAGICGNN_01612 1e-153 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HAGICGNN_01613 7.3e-107 ytaF P Probably functions as a manganese efflux pump
HAGICGNN_01614 5.3e-91 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HAGICGNN_01615 5.2e-153 ytbE S reductase
HAGICGNN_01616 8.1e-200 ytbD EGP Major facilitator Superfamily
HAGICGNN_01617 1.2e-64 ytcD K Transcriptional regulator
HAGICGNN_01618 1.8e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAGICGNN_01619 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HAGICGNN_01620 3.2e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HAGICGNN_01621 1.4e-254 dnaB L Membrane attachment protein
HAGICGNN_01622 6.3e-154 dnaI L Primosomal protein DnaI
HAGICGNN_01623 8.4e-103 ytxB S SNARE associated Golgi protein
HAGICGNN_01624 2.6e-152 ytxC S YtxC-like family
HAGICGNN_01625 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HAGICGNN_01626 3.4e-146 ysaA S HAD-hyrolase-like
HAGICGNN_01627 7.4e-311 lytS 2.7.13.3 T Histidine kinase
HAGICGNN_01628 8e-126 lytT T COG3279 Response regulator of the LytR AlgR family
HAGICGNN_01629 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HAGICGNN_01630 7.7e-110 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HAGICGNN_01632 1.5e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HAGICGNN_01633 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HAGICGNN_01634 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HAGICGNN_01635 1.9e-43 ysdA S Membrane
HAGICGNN_01636 7.6e-51 ysdB S Sigma-w pathway protein YsdB
HAGICGNN_01637 1.7e-204 ysdC G COG1363 Cellulase M and related proteins
HAGICGNN_01638 1e-184 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HAGICGNN_01639 1.9e-286 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HAGICGNN_01640 3.4e-305 araB 2.7.1.16 C Belongs to the ribulokinase family
HAGICGNN_01641 2.1e-131 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HAGICGNN_01642 6e-138 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HAGICGNN_01643 5e-210 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HAGICGNN_01644 7.1e-250 araN G carbohydrate transport
HAGICGNN_01645 3.5e-166 araP G carbohydrate transport
HAGICGNN_01646 8.4e-143 araQ G transport system permease
HAGICGNN_01647 4.3e-299 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HAGICGNN_01648 0.0 cstA T Carbon starvation protein
HAGICGNN_01649 1.9e-54 ysfE 4.4.1.5 E Glyoxalase-like domain
HAGICGNN_01650 4.9e-246 glcF C Glycolate oxidase
HAGICGNN_01651 3.4e-253 glcD 1.1.3.15 C Glycolate oxidase subunit
HAGICGNN_01652 1.6e-181 ysfB KT regulator
HAGICGNN_01653 7.6e-32 sspI S Belongs to the SspI family
HAGICGNN_01654 2.2e-123 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HAGICGNN_01655 8.9e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HAGICGNN_01656 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HAGICGNN_01657 2.2e-168 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HAGICGNN_01658 6.5e-38 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HAGICGNN_01659 1.4e-82 cvpA S membrane protein, required for colicin V production
HAGICGNN_01660 0.0 polX L COG1796 DNA polymerase IV (family X)
HAGICGNN_01661 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HAGICGNN_01662 7.3e-68 yshE S membrane
HAGICGNN_01663 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HAGICGNN_01664 1.8e-96 fadR K Transcriptional regulator
HAGICGNN_01665 2.3e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HAGICGNN_01666 3.8e-134 etfB C Electron transfer flavoprotein
HAGICGNN_01667 8.4e-171 etfA C Electron transfer flavoprotein
HAGICGNN_01668 1.3e-295 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HAGICGNN_01669 3.3e-52 trxA O Belongs to the thioredoxin family
HAGICGNN_01670 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HAGICGNN_01671 1.9e-204 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HAGICGNN_01672 1.2e-79 yslB S Protein of unknown function (DUF2507)
HAGICGNN_01673 4.5e-106 sdhC C succinate dehydrogenase
HAGICGNN_01674 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HAGICGNN_01675 1.1e-146 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HAGICGNN_01676 2.1e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HAGICGNN_01677 3.3e-30 gerE K Transcriptional regulator
HAGICGNN_01678 2.5e-74 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_01679 6.2e-151 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HAGICGNN_01680 3.5e-189 gerM S COG5401 Spore germination protein
HAGICGNN_01681 1.5e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HAGICGNN_01682 1.6e-100 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HAGICGNN_01683 7.2e-89 ysnB S Phosphoesterase
HAGICGNN_01685 5.5e-123 ysnF S protein conserved in bacteria
HAGICGNN_01686 5.8e-74 ysnE K acetyltransferase
HAGICGNN_01688 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HAGICGNN_01689 2.1e-83 ilvN 2.2.1.6 E Acetolactate synthase
HAGICGNN_01690 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HAGICGNN_01691 1.6e-285 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HAGICGNN_01692 1e-196 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HAGICGNN_01693 4.5e-274 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAGICGNN_01694 1.8e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HAGICGNN_01695 2e-183 ysoA H Tetratricopeptide repeat
HAGICGNN_01696 1.6e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HAGICGNN_01697 5e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HAGICGNN_01698 4.3e-308 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HAGICGNN_01699 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HAGICGNN_01700 9.8e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HAGICGNN_01701 7.8e-88 ysxD
HAGICGNN_01702 4.7e-244 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HAGICGNN_01703 6.1e-146 hemX O cytochrome C
HAGICGNN_01704 1.2e-169 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HAGICGNN_01705 7.9e-135 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HAGICGNN_01706 4.5e-180 hemB 4.2.1.24 H Belongs to the ALAD family
HAGICGNN_01707 1.5e-244 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HAGICGNN_01708 5.8e-115 spoVID M stage VI sporulation protein D
HAGICGNN_01709 2e-186 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HAGICGNN_01710 3.6e-25
HAGICGNN_01711 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HAGICGNN_01712 2.9e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HAGICGNN_01713 1.6e-116 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HAGICGNN_01714 4.9e-158 spoIIB S Sporulation related domain
HAGICGNN_01715 2.5e-98 maf D septum formation protein Maf
HAGICGNN_01716 1.9e-124 radC E Belongs to the UPF0758 family
HAGICGNN_01717 5.3e-184 mreB D Rod shape-determining protein MreB
HAGICGNN_01718 2.9e-154 mreC M Involved in formation and maintenance of cell shape
HAGICGNN_01719 9.3e-84 mreD M shape-determining protein
HAGICGNN_01720 4e-119 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HAGICGNN_01721 3.1e-142 minD D Belongs to the ParA family
HAGICGNN_01722 2.3e-142 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HAGICGNN_01723 2.1e-157 spoIVFB S Stage IV sporulation protein
HAGICGNN_01724 2.9e-48 rplU J This protein binds to 23S rRNA in the presence of protein L20
HAGICGNN_01725 4.1e-56 ysxB J ribosomal protein
HAGICGNN_01726 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HAGICGNN_01727 7.6e-103 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HAGICGNN_01728 2.1e-225 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HAGICGNN_01729 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HAGICGNN_01730 1.9e-161 pheA 4.2.1.51 E Prephenate dehydratase
HAGICGNN_01731 1.8e-90 niaR S small molecule binding protein (contains 3H domain)
HAGICGNN_01732 2.8e-208 nifS 2.8.1.7 E Cysteine desulfurase
HAGICGNN_01733 1.1e-268 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HAGICGNN_01734 1.6e-128 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HAGICGNN_01735 7.3e-203 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HAGICGNN_01736 2.3e-111 safA M spore coat assembly protein SafA
HAGICGNN_01737 2.7e-42 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAGICGNN_01738 4.4e-116 yebC K transcriptional regulatory protein
HAGICGNN_01739 3.7e-247 alsT E Sodium alanine symporter
HAGICGNN_01740 5.5e-50 S Family of unknown function (DUF5412)
HAGICGNN_01742 7.4e-115 yrzF T serine threonine protein kinase
HAGICGNN_01743 1.6e-183 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HAGICGNN_01744 8.2e-246 csbX EGP Major facilitator Superfamily
HAGICGNN_01745 8.9e-87 bofC S BofC C-terminal domain
HAGICGNN_01746 2.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HAGICGNN_01747 2.1e-185 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HAGICGNN_01748 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HAGICGNN_01749 1.1e-189 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HAGICGNN_01750 5.7e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HAGICGNN_01751 6.7e-38 yajC U Preprotein translocase subunit YajC
HAGICGNN_01752 1.7e-73 yrzE S Protein of unknown function (DUF3792)
HAGICGNN_01753 1.9e-105 yrbG S membrane
HAGICGNN_01754 2.7e-264 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_01755 1.8e-47 yrzD S Post-transcriptional regulator
HAGICGNN_01756 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HAGICGNN_01757 3.1e-76 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HAGICGNN_01758 1.2e-44 yrvD S Lipopolysaccharide assembly protein A domain
HAGICGNN_01759 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HAGICGNN_01760 3.2e-89 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HAGICGNN_01761 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HAGICGNN_01762 8.5e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HAGICGNN_01763 4.4e-246 lytH 3.5.1.28 M COG3103 SH3 domain protein
HAGICGNN_01765 7.7e-241 hisS 6.1.1.21 J histidyl-tRNA synthetase
HAGICGNN_01766 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HAGICGNN_01767 3.8e-134 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HAGICGNN_01768 5.9e-233 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HAGICGNN_01769 1.2e-70 cymR K Transcriptional regulator
HAGICGNN_01770 3e-204 iscS 2.8.1.7 E Cysteine desulfurase
HAGICGNN_01771 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HAGICGNN_01772 1.4e-15 S COG0457 FOG TPR repeat
HAGICGNN_01773 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HAGICGNN_01774 5.1e-90 yrrD S protein conserved in bacteria
HAGICGNN_01775 9.8e-31 yrzR
HAGICGNN_01776 3.6e-08 S Protein of unknown function (DUF3918)
HAGICGNN_01777 2.9e-164 yrrI S AI-2E family transporter
HAGICGNN_01778 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HAGICGNN_01779 1.7e-41 yrzL S Belongs to the UPF0297 family
HAGICGNN_01780 1.5e-68 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HAGICGNN_01781 1.5e-43 yrzB S Belongs to the UPF0473 family
HAGICGNN_01782 8.7e-177 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HAGICGNN_01783 6.1e-117 yrrM 2.1.1.104 S O-methyltransferase
HAGICGNN_01784 8.3e-168 yegQ O Peptidase U32
HAGICGNN_01785 4.4e-244 yegQ O COG0826 Collagenase and related proteases
HAGICGNN_01786 1.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
HAGICGNN_01787 4.1e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HAGICGNN_01788 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HAGICGNN_01789 1e-53 yrrS S Protein of unknown function (DUF1510)
HAGICGNN_01790 2.9e-25 yrzA S Protein of unknown function (DUF2536)
HAGICGNN_01791 8.1e-114 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HAGICGNN_01792 3e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HAGICGNN_01793 6.3e-168 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HAGICGNN_01794 5.7e-203 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HAGICGNN_01795 3.9e-149 czcD P COG1230 Co Zn Cd efflux system component
HAGICGNN_01796 1.9e-181 trkA P Oxidoreductase
HAGICGNN_01798 3e-76 yrhD S Protein of unknown function (DUF1641)
HAGICGNN_01799 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HAGICGNN_01800 5.6e-59 yrhF S Uncharacterized conserved protein (DUF2294)
HAGICGNN_01801 1.4e-139 focA P Formate nitrite
HAGICGNN_01803 4.2e-87 yrhH Q methyltransferase
HAGICGNN_01804 1.5e-98 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HAGICGNN_01805 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HAGICGNN_01806 1.1e-38 yrhK S YrhK-like protein
HAGICGNN_01807 2.7e-146 yrhO K Archaeal transcriptional regulator TrmB
HAGICGNN_01808 6.6e-100 yrhP E LysE type translocator
HAGICGNN_01809 2.6e-242 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_01811 0.0 levR K PTS system fructose IIA component
HAGICGNN_01812 1.2e-68 levD 2.7.1.202 G PTS system fructose IIA component
HAGICGNN_01813 2.9e-79 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HAGICGNN_01814 2.4e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HAGICGNN_01815 2.6e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HAGICGNN_01816 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HAGICGNN_01817 2.1e-88 yhbO 1.11.1.6, 3.5.1.124 S protease
HAGICGNN_01818 4.3e-189 adhA 1.1.1.1 C alcohol dehydrogenase
HAGICGNN_01819 2.2e-40 yraB K helix_turn_helix, mercury resistance
HAGICGNN_01820 8e-12 rmeD K MerR family transcriptional regulator
HAGICGNN_01821 7.1e-14 ptsH G phosphocarrier protein HPr
HAGICGNN_01822 6.8e-47 yraD M Spore coat protein
HAGICGNN_01823 7.5e-26 yraE
HAGICGNN_01824 1.5e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HAGICGNN_01825 1.8e-60 yraF M Spore coat protein
HAGICGNN_01826 1.1e-34 yraG
HAGICGNN_01827 7.6e-128 S Alpha beta hydrolase
HAGICGNN_01828 1.9e-37 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_01830 1.9e-147 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HAGICGNN_01832 9.5e-195 yraM S PrpF protein
HAGICGNN_01833 2.6e-155 yraN K Transcriptional regulator
HAGICGNN_01834 3.3e-218 yraO C Citrate transporter
HAGICGNN_01835 5.7e-103 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HAGICGNN_01836 8.3e-135 tktA 2.2.1.1 G COG3959 Transketolase, N-terminal subunit
HAGICGNN_01837 1.9e-151 2.2.1.1 G Transketolase, pyrimidine binding domain
HAGICGNN_01838 1.1e-112 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_01839 3.3e-210 rbtT P Major Facilitator Superfamily
HAGICGNN_01841 6.2e-99 K helix_turn_helix gluconate operon transcriptional repressor
HAGICGNN_01842 7.4e-107 aadK G Streptomycin adenylyltransferase
HAGICGNN_01843 1.6e-29 aadK G Streptomycin adenylyltransferase
HAGICGNN_01844 3.9e-78 bltD 2.3.1.57 K FR47-like protein
HAGICGNN_01845 1.5e-86 yrdA S DinB family
HAGICGNN_01846 2.7e-152 rhaS5 K AraC-like ligand binding domain
HAGICGNN_01847 1.6e-158 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HAGICGNN_01848 2.1e-250 cscA 3.2.1.26 GH32 G invertase
HAGICGNN_01849 8.8e-197 rafB P LacY proton/sugar symporter
HAGICGNN_01850 2.5e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
HAGICGNN_01851 1.1e-148 msmF P Binding-protein-dependent transport system inner membrane component
HAGICGNN_01852 4.2e-226 msmE G Bacterial extracellular solute-binding protein
HAGICGNN_01853 8.4e-163 scrR K transcriptional
HAGICGNN_01854 6.5e-67 K Transcriptional regulator
HAGICGNN_01856 1.3e-216 cypA C Cytochrome P450
HAGICGNN_01857 1.8e-128 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HAGICGNN_01858 2.8e-180 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HAGICGNN_01859 6.9e-148 gltR K LysR substrate binding domain
HAGICGNN_01860 2.7e-54 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAGICGNN_01861 1e-82 yvbV1 EG Permeases of the drug metabolite transporter (DMT) superfamily
HAGICGNN_01862 3.6e-11 yodA S tautomerase
HAGICGNN_01863 5.2e-12 L COG2963 Transposase and inactivated derivatives
HAGICGNN_01864 1.4e-98 yrkN K Acetyltransferase (GNAT) family
HAGICGNN_01865 1.3e-202 yrkO P Protein of unknown function (DUF418)
HAGICGNN_01866 1.3e-125 T Transcriptional regulator
HAGICGNN_01867 3.9e-232 yrkQ T Histidine kinase
HAGICGNN_01868 2e-68 psiE S Protein PsiE homolog
HAGICGNN_01869 1.6e-39
HAGICGNN_01870 7.7e-29
HAGICGNN_01871 3e-61 L nucleic acid phosphodiester bond hydrolysis
HAGICGNN_01872 9.5e-09 L nucleic acid phosphodiester bond hydrolysis
HAGICGNN_01875 1.2e-128 S Aspartate phosphatase response regulator
HAGICGNN_01877 8.6e-71 ylbE GM Nucleoside-diphosphate-sugar epimerases
HAGICGNN_01879 1.3e-24 K MerR HTH family regulatory protein
HAGICGNN_01880 1e-77 yijE EG EamA-like transporter family
HAGICGNN_01882 9.4e-150 S Serine aminopeptidase, S33
HAGICGNN_01884 6.2e-53 ydcG S EVE domain
HAGICGNN_01885 3.2e-60 2.8.1.7, 4.4.1.16 P Rhodanese Homology Domain
HAGICGNN_01886 4.7e-62 hosA K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_01887 9.1e-78 S Protein of unknown function with HXXEE motif
HAGICGNN_01888 1.8e-95 ywrO S Flavodoxin-like fold
HAGICGNN_01890 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_01891 1e-90 yqaB E IrrE N-terminal-like domain
HAGICGNN_01893 3.6e-58 adk 2.7.4.3 F adenylate kinase activity
HAGICGNN_01894 6.4e-67 S Bacteriophage holin family
HAGICGNN_01895 2.6e-125 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HAGICGNN_01897 1.2e-272 L nucleic acid phosphodiester bond hydrolysis
HAGICGNN_01898 1.5e-69 K MerR family transcriptional regulator
HAGICGNN_01899 1.3e-138 yvgN 1.1.1.346 S Reductase
HAGICGNN_01900 1.1e-129 S Aspartate phosphatase response regulator
HAGICGNN_01904 4e-177 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HAGICGNN_01905 1.7e-143
HAGICGNN_01906 2.5e-278 cisA2 L Recombinase
HAGICGNN_01907 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_01908 7.4e-68 nucB M Deoxyribonuclease NucA/NucB
HAGICGNN_01909 1.6e-110 yqeB
HAGICGNN_01910 8e-29 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HAGICGNN_01911 3.1e-33 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HAGICGNN_01912 8e-98 yqeD S SNARE associated Golgi protein
HAGICGNN_01913 1.6e-124 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HAGICGNN_01914 3.3e-135 yqeF E GDSL-like Lipase/Acylhydrolase
HAGICGNN_01916 5.3e-95 yqeG S hydrolase of the HAD superfamily
HAGICGNN_01917 1.5e-211 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HAGICGNN_01918 8.4e-151 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HAGICGNN_01919 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HAGICGNN_01920 2.9e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HAGICGNN_01921 2.6e-100 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HAGICGNN_01922 6.4e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HAGICGNN_01923 1.2e-132 yqeM Q Methyltransferase
HAGICGNN_01924 6.1e-146 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAGICGNN_01925 1.4e-78 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HAGICGNN_01926 5.7e-103 comEB 3.5.4.12 F ComE operon protein 2
HAGICGNN_01927 0.0 comEC S Competence protein ComEC
HAGICGNN_01928 1.2e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
HAGICGNN_01929 4.8e-36 rpsT J Binds directly to 16S ribosomal RNA
HAGICGNN_01930 1.7e-199 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HAGICGNN_01931 1.8e-218 spoIIP M stage II sporulation protein P
HAGICGNN_01932 1.2e-50 yqxA S Protein of unknown function (DUF3679)
HAGICGNN_01933 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HAGICGNN_01934 3.1e-209 hemN H Involved in the biosynthesis of porphyrin-containing compound
HAGICGNN_01935 7.5e-186 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HAGICGNN_01936 1.6e-73 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HAGICGNN_01937 0.0 dnaK O Heat shock 70 kDa protein
HAGICGNN_01938 3e-180 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HAGICGNN_01939 1.3e-173 prmA J Methylates ribosomal protein L11
HAGICGNN_01940 7e-136 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HAGICGNN_01941 9.7e-258 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HAGICGNN_01942 2.1e-153 yqeW P COG1283 Na phosphate symporter
HAGICGNN_01943 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HAGICGNN_01944 2.5e-61 yqeY S Yqey-like protein
HAGICGNN_01945 5.6e-218 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HAGICGNN_01946 2.4e-120 yqfA S UPF0365 protein
HAGICGNN_01947 5.5e-10 yqfB
HAGICGNN_01948 4.6e-45 yqfC S sporulation protein YqfC
HAGICGNN_01949 3.9e-178 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HAGICGNN_01950 3.6e-174 phoH T Phosphate starvation-inducible protein PhoH
HAGICGNN_01952 0.0 yqfF S membrane-associated HD superfamily hydrolase
HAGICGNN_01953 8.2e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HAGICGNN_01954 4.1e-57 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HAGICGNN_01955 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HAGICGNN_01956 9.9e-166 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HAGICGNN_01957 4.2e-18 S YqzL-like protein
HAGICGNN_01958 5.9e-143 recO L Involved in DNA repair and RecF pathway recombination
HAGICGNN_01959 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HAGICGNN_01960 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HAGICGNN_01961 4.5e-112 ccpN K CBS domain
HAGICGNN_01962 4.1e-147 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HAGICGNN_01963 2.7e-85 yaiI S Belongs to the UPF0178 family
HAGICGNN_01964 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HAGICGNN_01965 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HAGICGNN_01966 3.8e-60 cccA C COG2010 Cytochrome c, mono- and diheme variants
HAGICGNN_01967 3.6e-109 trmK 2.1.1.217 S SAM-dependent methyltransferase
HAGICGNN_01968 4.6e-205 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HAGICGNN_01969 2.3e-173 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HAGICGNN_01970 1.9e-26 yqfQ S YqfQ-like protein
HAGICGNN_01971 7.5e-239 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HAGICGNN_01972 1.1e-164 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HAGICGNN_01973 7.4e-34 yqfT S Protein of unknown function (DUF2624)
HAGICGNN_01974 6.1e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HAGICGNN_01975 3e-75 zur P Belongs to the Fur family
HAGICGNN_01976 5.1e-107 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HAGICGNN_01977 2.4e-60 yqfX S membrane
HAGICGNN_01978 2.4e-201 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HAGICGNN_01979 2.4e-44 yqfZ M LysM domain
HAGICGNN_01980 1.9e-125 yqgB S Protein of unknown function (DUF1189)
HAGICGNN_01981 2e-72 yqgC S protein conserved in bacteria
HAGICGNN_01982 4.1e-115 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HAGICGNN_01983 2.6e-228 yqgE EGP Major facilitator superfamily
HAGICGNN_01984 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HAGICGNN_01985 1e-132 pstS P Phosphate
HAGICGNN_01986 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HAGICGNN_01987 1.8e-156 pstA P Phosphate transport system permease
HAGICGNN_01988 1.5e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAGICGNN_01989 1.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HAGICGNN_01990 5.6e-72 yqzC S YceG-like family
HAGICGNN_01991 1e-49 yqzD
HAGICGNN_01993 1.3e-167 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HAGICGNN_01994 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HAGICGNN_01995 4.2e-90 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HAGICGNN_01996 1.2e-08 yqgO
HAGICGNN_01997 3.6e-221 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HAGICGNN_01998 3.4e-27 yqgQ S Protein conserved in bacteria
HAGICGNN_01999 1.9e-178 glcK 2.7.1.2 G Glucokinase
HAGICGNN_02000 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HAGICGNN_02001 5.7e-203 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HAGICGNN_02002 1.1e-168 yqgU
HAGICGNN_02003 1.5e-49 yqgV S Thiamine-binding protein
HAGICGNN_02004 4.4e-22 yqgW S Protein of unknown function (DUF2759)
HAGICGNN_02005 2e-120 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HAGICGNN_02006 5.3e-37 yqgY S Protein of unknown function (DUF2626)
HAGICGNN_02007 1.2e-61 yqgZ 1.20.4.1 P Belongs to the ArsC family
HAGICGNN_02009 7.6e-136 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAGICGNN_02010 5.7e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HAGICGNN_02011 7.5e-156 corA P Mg2 transporter protein
HAGICGNN_02012 9.1e-50 ylbB S Cbs domain
HAGICGNN_02013 6.4e-196 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HAGICGNN_02014 6.9e-163 comGB NU COG1459 Type II secretory pathway, component PulF
HAGICGNN_02015 5.2e-47 comGC U Required for transformation and DNA binding
HAGICGNN_02016 9.5e-58 gspH NU protein transport across the cell outer membrane
HAGICGNN_02017 1.5e-45 comGE
HAGICGNN_02018 2.1e-45 S ComG operon protein 7
HAGICGNN_02019 2.6e-25 yqzE S YqzE-like protein
HAGICGNN_02020 7.7e-52 yqzG S Protein of unknown function (DUF3889)
HAGICGNN_02021 2.7e-100 yqxM
HAGICGNN_02022 1.1e-56 sipW 3.4.21.89 U Signal peptidase
HAGICGNN_02023 8.4e-137 tasA S Cell division protein FtsN
HAGICGNN_02024 1e-54 sinR K transcriptional
HAGICGNN_02025 2.6e-22 sinI S Anti-repressor SinI
HAGICGNN_02026 9e-147 yqhG S Bacterial protein YqhG of unknown function
HAGICGNN_02027 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HAGICGNN_02028 1.3e-191 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HAGICGNN_02029 4.9e-246 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAGICGNN_02030 2.3e-281 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HAGICGNN_02031 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
HAGICGNN_02032 2.4e-158 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HAGICGNN_02033 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HAGICGNN_02034 1.9e-161 yqhO S esterase of the alpha-beta hydrolase superfamily
HAGICGNN_02035 1.1e-60 yqhP
HAGICGNN_02036 2.2e-171 yqhQ S Protein of unknown function (DUF1385)
HAGICGNN_02037 1.2e-89 yqhR S Conserved membrane protein YqhR
HAGICGNN_02038 1e-75 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HAGICGNN_02039 3e-169 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HAGICGNN_02040 2.7e-97 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HAGICGNN_02041 1e-36 yqhV S Protein of unknown function (DUF2619)
HAGICGNN_02042 6.1e-163 spoIIIAA S stage III sporulation protein AA
HAGICGNN_02043 2.3e-82 spoIIIAB S Stage III sporulation protein
HAGICGNN_02044 7.6e-29 spoIIIAC S stage III sporulation protein AC
HAGICGNN_02045 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HAGICGNN_02046 1.5e-193 spoIIIAE S stage III sporulation protein AE
HAGICGNN_02047 1.2e-98 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HAGICGNN_02048 1e-106 spoIIIAG S stage III sporulation protein AG
HAGICGNN_02049 7.9e-80 spoIIIAH S SpoIIIAH-like protein
HAGICGNN_02050 4.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HAGICGNN_02051 5e-254 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HAGICGNN_02052 2.4e-66 yqhY S protein conserved in bacteria
HAGICGNN_02053 1.3e-64 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HAGICGNN_02054 5.1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HAGICGNN_02055 7.4e-242 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAGICGNN_02056 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HAGICGNN_02057 5.2e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HAGICGNN_02058 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HAGICGNN_02059 2.4e-153 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HAGICGNN_02060 1.1e-77 argR K Regulates arginine biosynthesis genes
HAGICGNN_02061 3.8e-283 recN L May be involved in recombinational repair of damaged DNA
HAGICGNN_02062 1.2e-233 rseP 3.4.21.116 M Stage IV sporulation protein B
HAGICGNN_02063 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HAGICGNN_02066 1.7e-207 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HAGICGNN_02067 1.9e-25
HAGICGNN_02068 1.6e-103 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HAGICGNN_02069 1.1e-117 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HAGICGNN_02070 2.8e-205 mmgA 2.3.1.9 I Belongs to the thiolase family
HAGICGNN_02071 1.7e-146 hbdA 1.1.1.157 I Dehydrogenase
HAGICGNN_02072 2e-203 mmgC I acyl-CoA dehydrogenase
HAGICGNN_02073 4.4e-200 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HAGICGNN_02074 3.6e-263 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HAGICGNN_02075 9.6e-153 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HAGICGNN_02076 9.3e-31 yqzF S Protein of unknown function (DUF2627)
HAGICGNN_02077 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HAGICGNN_02078 1.7e-146 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HAGICGNN_02079 4.5e-205 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HAGICGNN_02080 2.6e-197 buk 2.7.2.7 C Belongs to the acetokinase family
HAGICGNN_02081 4e-262 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAGICGNN_02082 1e-184 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAGICGNN_02083 3.3e-183 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAGICGNN_02084 2.5e-215 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAGICGNN_02085 8e-146 bmrR K helix_turn_helix, mercury resistance
HAGICGNN_02086 2.5e-201 norA EGP Major facilitator Superfamily
HAGICGNN_02087 2.2e-157 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HAGICGNN_02088 3e-75 yqiW S Belongs to the UPF0403 family
HAGICGNN_02089 2.5e-133 artP ET Belongs to the bacterial solute-binding protein 3 family
HAGICGNN_02090 2.1e-104 artQ E COG0765 ABC-type amino acid transport system, permease component
HAGICGNN_02091 1.6e-126 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HAGICGNN_02092 1.9e-170 yqjA S Putative aromatic acid exporter C-terminal domain
HAGICGNN_02093 2.3e-93 yqjB S protein conserved in bacteria
HAGICGNN_02095 3.5e-65 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HAGICGNN_02096 3.7e-274 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HAGICGNN_02097 4.9e-199 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HAGICGNN_02098 3.2e-130 yqjF S Uncharacterized conserved protein (COG2071)
HAGICGNN_02099 6.5e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAGICGNN_02100 4.7e-24 yqzJ
HAGICGNN_02101 2e-225 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAGICGNN_02102 7.7e-266 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAGICGNN_02103 6.5e-284 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HAGICGNN_02104 1.4e-167 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HAGICGNN_02105 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HAGICGNN_02106 9.6e-138 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAGICGNN_02107 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HAGICGNN_02108 3.4e-297 rocB E arginine degradation protein
HAGICGNN_02109 1.1e-139 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAGICGNN_02110 2.1e-166 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HAGICGNN_02111 5.2e-139 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_02112 8.5e-238 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HAGICGNN_02113 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HAGICGNN_02114 7.7e-67 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAGICGNN_02116 4.3e-212 yqjV G Major Facilitator Superfamily
HAGICGNN_02118 5.6e-236 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAGICGNN_02119 1.5e-50 S YolD-like protein
HAGICGNN_02120 2e-85 yqjY K acetyltransferase
HAGICGNN_02121 9.8e-50 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HAGICGNN_02122 4.3e-173 yqkA K GrpB protein
HAGICGNN_02123 2.8e-54 yqkB S Belongs to the HesB IscA family
HAGICGNN_02124 3.6e-38 yqkC S Protein of unknown function (DUF2552)
HAGICGNN_02125 7.7e-158 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HAGICGNN_02126 5.5e-09 yqkE S Protein of unknown function (DUF3886)
HAGICGNN_02127 9.1e-159 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HAGICGNN_02129 7.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HAGICGNN_02130 9.9e-211 yqxK 3.6.4.12 L DNA helicase
HAGICGNN_02131 1.5e-56 ansR K Transcriptional regulator
HAGICGNN_02132 1.5e-183 ansA 3.5.1.1 EJ L-asparaginase
HAGICGNN_02133 8.3e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HAGICGNN_02134 2.4e-227 mleN C Na H antiporter
HAGICGNN_02135 9.2e-237 mleA 1.1.1.38 C malic enzyme
HAGICGNN_02136 1.9e-26 yqkK
HAGICGNN_02137 9.1e-105 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HAGICGNN_02138 2.4e-80 fur P Belongs to the Fur family
HAGICGNN_02139 1.1e-36 S Protein of unknown function (DUF4227)
HAGICGNN_02140 2.2e-165 xerD L recombinase XerD
HAGICGNN_02141 4.1e-228 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HAGICGNN_02142 1.6e-146 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HAGICGNN_02143 6.7e-207 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HAGICGNN_02144 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HAGICGNN_02145 5.1e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HAGICGNN_02146 7.7e-135 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_02147 2.9e-108 spoVAA S Stage V sporulation protein AA
HAGICGNN_02148 2.5e-66 spoVAB S Stage V sporulation protein AB
HAGICGNN_02149 2.3e-78 spoVAC S stage V sporulation protein AC
HAGICGNN_02150 1.1e-186 spoVAD I Stage V sporulation protein AD
HAGICGNN_02151 2.2e-57 spoVAEB S stage V sporulation protein
HAGICGNN_02152 9.8e-109 spoVAEA S stage V sporulation protein
HAGICGNN_02153 9.5e-267 spoVAF EG Stage V sporulation protein AF
HAGICGNN_02154 1.2e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HAGICGNN_02155 3.4e-147 ypuA S Secreted protein
HAGICGNN_02156 4e-80 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HAGICGNN_02158 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HAGICGNN_02160 8e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HAGICGNN_02161 3.6e-52
HAGICGNN_02162 2.1e-194 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HAGICGNN_02163 9.1e-113 ribE 2.5.1.9 H Riboflavin synthase
HAGICGNN_02164 1.9e-225 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HAGICGNN_02165 6.6e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HAGICGNN_02166 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_02167 1.5e-81 ypuF S Domain of unknown function (DUF309)
HAGICGNN_02168 5.3e-125 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HAGICGNN_02169 1.3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HAGICGNN_02170 2.3e-93 ypuI S Protein of unknown function (DUF3907)
HAGICGNN_02171 2.3e-204 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HAGICGNN_02172 3.5e-103 spmA S Spore maturation protein
HAGICGNN_02173 7.1e-87 spmB S Spore maturation protein
HAGICGNN_02174 1.4e-131 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HAGICGNN_02175 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HAGICGNN_02176 9.9e-310 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HAGICGNN_02177 3.2e-209 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HAGICGNN_02178 9.7e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_02179 0.0 resE 2.7.13.3 T Histidine kinase
HAGICGNN_02180 8.5e-102 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_02181 2.1e-178 rsiX
HAGICGNN_02182 2.3e-123 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HAGICGNN_02183 2.9e-290 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAGICGNN_02184 1.3e-09
HAGICGNN_02185 3e-83 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HAGICGNN_02186 4.7e-41 fer C Ferredoxin
HAGICGNN_02187 4.6e-186 ypbB 5.1.3.1 S protein conserved in bacteria
HAGICGNN_02188 2.4e-273 recQ 3.6.4.12 L DNA helicase
HAGICGNN_02189 2e-85 ypbD S metal-dependent membrane protease
HAGICGNN_02190 4.6e-68 ypbE M Lysin motif
HAGICGNN_02191 2.5e-77 ypbF S Protein of unknown function (DUF2663)
HAGICGNN_02192 7.5e-138 ypbG S Calcineurin-like phosphoesterase superfamily domain
HAGICGNN_02193 1.2e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HAGICGNN_02194 9.8e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HAGICGNN_02195 7.9e-169 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HAGICGNN_02196 1.8e-116 prsW S Involved in the degradation of specific anti-sigma factors
HAGICGNN_02197 1.7e-152 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HAGICGNN_02198 1.6e-249 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HAGICGNN_02199 2.6e-99 ypfA M Flagellar protein YcgR
HAGICGNN_02200 2e-22 S Family of unknown function (DUF5359)
HAGICGNN_02201 1.3e-109 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HAGICGNN_02202 6.2e-205 rpsA 1.17.7.4 J Ribosomal protein S1
HAGICGNN_02203 1.1e-173 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HAGICGNN_02204 1e-07 S YpzI-like protein
HAGICGNN_02205 8.4e-97 yphA
HAGICGNN_02206 4.7e-160 seaA S YIEGIA protein
HAGICGNN_02207 1.3e-27 ypzH
HAGICGNN_02208 1.4e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HAGICGNN_02209 2.4e-176 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HAGICGNN_02210 6.3e-20 yphE S Protein of unknown function (DUF2768)
HAGICGNN_02211 2.1e-129 yphF
HAGICGNN_02212 4.1e-278 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HAGICGNN_02213 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HAGICGNN_02214 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HAGICGNN_02215 3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HAGICGNN_02216 5.3e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HAGICGNN_02217 5.2e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HAGICGNN_02218 5.4e-192 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HAGICGNN_02219 4.5e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HAGICGNN_02220 4.5e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HAGICGNN_02221 2.1e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HAGICGNN_02222 1.4e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HAGICGNN_02223 9.6e-62 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HAGICGNN_02224 1e-279 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HAGICGNN_02225 3.2e-173 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HAGICGNN_02226 1.2e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HAGICGNN_02227 9.1e-105 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HAGICGNN_02228 5.3e-223 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HAGICGNN_02229 1e-134 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HAGICGNN_02230 3.6e-199 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HAGICGNN_02231 8.9e-201 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HAGICGNN_02232 3e-224 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HAGICGNN_02233 4.9e-227 S COG0457 FOG TPR repeat
HAGICGNN_02234 1.8e-98 ypiB S Belongs to the UPF0302 family
HAGICGNN_02235 2.1e-68 ypiF S Protein of unknown function (DUF2487)
HAGICGNN_02236 2.7e-96 qcrA C Menaquinol-cytochrome c reductase
HAGICGNN_02237 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HAGICGNN_02238 3.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HAGICGNN_02239 1.9e-95 ypjA S membrane
HAGICGNN_02240 2e-138 ypjB S sporulation protein
HAGICGNN_02241 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HAGICGNN_02242 1e-54 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HAGICGNN_02243 7.2e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HAGICGNN_02244 5.7e-68 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HAGICGNN_02245 1.9e-124 bshB1 S proteins, LmbE homologs
HAGICGNN_02246 3e-204 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HAGICGNN_02247 1.2e-198 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HAGICGNN_02248 1.3e-176 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HAGICGNN_02249 1.6e-146 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HAGICGNN_02250 1.2e-147 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HAGICGNN_02251 1e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HAGICGNN_02252 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HAGICGNN_02253 4.3e-22 ypmA S Protein of unknown function (DUF4264)
HAGICGNN_02254 2.7e-77 ypmB S protein conserved in bacteria
HAGICGNN_02255 7e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HAGICGNN_02256 2.9e-251 asnS 6.1.1.22 J asparaginyl-tRNA
HAGICGNN_02257 2.2e-128 dnaD L DNA replication protein DnaD
HAGICGNN_02258 2.4e-121 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HAGICGNN_02259 4.2e-78 ypoC
HAGICGNN_02260 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HAGICGNN_02261 2.5e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HAGICGNN_02262 9.5e-175 yppC S Protein of unknown function (DUF2515)
HAGICGNN_02265 4.4e-11 yppE S Bacterial domain of unknown function (DUF1798)
HAGICGNN_02267 1.9e-30 yppG S YppG-like protein
HAGICGNN_02268 2.5e-63 hspX O Belongs to the small heat shock protein (HSP20) family
HAGICGNN_02269 2.4e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HAGICGNN_02270 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HAGICGNN_02271 1.5e-217 yprB L RNase_H superfamily
HAGICGNN_02272 6.3e-91 ypsA S Belongs to the UPF0398 family
HAGICGNN_02273 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HAGICGNN_02274 1.2e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HAGICGNN_02276 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HAGICGNN_02277 6.1e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_02278 1.2e-154 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HAGICGNN_02279 1.6e-175 ptxS K transcriptional
HAGICGNN_02280 3.5e-177 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HAGICGNN_02281 1.1e-99 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HAGICGNN_02282 4.4e-167 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HAGICGNN_02283 2.5e-286 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HAGICGNN_02284 4.1e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HAGICGNN_02285 3.1e-216 pbuX F xanthine
HAGICGNN_02286 6.1e-194 bcsA Q Naringenin-chalcone synthase
HAGICGNN_02287 2.1e-80 ypbQ S protein conserved in bacteria
HAGICGNN_02288 0.0 ypbR S Dynamin family
HAGICGNN_02289 1.2e-36 ypbS S Protein of unknown function (DUF2533)
HAGICGNN_02290 2e-07
HAGICGNN_02292 1.6e-160 polA 2.7.7.7 L 5'3' exonuclease
HAGICGNN_02294 8.2e-64 rnhA 3.1.26.4 L Ribonuclease
HAGICGNN_02295 7.2e-104 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HAGICGNN_02296 1e-134 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HAGICGNN_02297 2.4e-26 ypeQ S Zinc-finger
HAGICGNN_02298 1.6e-31 S Protein of unknown function (DUF2564)
HAGICGNN_02299 4.5e-17 degR
HAGICGNN_02300 7.9e-31 cspD K Cold-shock protein
HAGICGNN_02301 3.4e-211 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HAGICGNN_02302 1.7e-173 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HAGICGNN_02303 2.5e-83 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HAGICGNN_02304 5.8e-101 ypgQ S phosphohydrolase
HAGICGNN_02305 5.4e-153 ypgR C COG0694 Thioredoxin-like proteins and domains
HAGICGNN_02306 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HAGICGNN_02307 1.5e-74 yphP S Belongs to the UPF0403 family
HAGICGNN_02308 3.5e-135 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HAGICGNN_02309 1.4e-110 ypjP S YpjP-like protein
HAGICGNN_02310 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HAGICGNN_02311 2.1e-151 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HAGICGNN_02312 2.7e-88 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HAGICGNN_02313 2.1e-103 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HAGICGNN_02314 5.6e-107 hlyIII S protein, Hemolysin III
HAGICGNN_02315 9.5e-170 pspF K Transcriptional regulator
HAGICGNN_02316 1.6e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HAGICGNN_02317 2.6e-39 ypmP S Protein of unknown function (DUF2535)
HAGICGNN_02318 1.2e-103 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HAGICGNN_02319 8.5e-134 ypmR E GDSL-like Lipase/Acylhydrolase
HAGICGNN_02320 3.3e-95 ypmS S protein conserved in bacteria
HAGICGNN_02321 2.1e-28 ypmT S Uncharacterized ympT
HAGICGNN_02322 8.7e-219 mepA V MATE efflux family protein
HAGICGNN_02323 1.8e-69 ypoP K transcriptional
HAGICGNN_02324 1.2e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HAGICGNN_02325 3.2e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HAGICGNN_02326 2.4e-123 4.2.1.115 GM Polysaccharide biosynthesis protein
HAGICGNN_02327 5.6e-198 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HAGICGNN_02328 2.2e-168 cgeB S Spore maturation protein
HAGICGNN_02329 8.2e-53 cgeA
HAGICGNN_02330 6.3e-32 cgeC
HAGICGNN_02331 1.1e-229 cgeD M maturation of the outermost layer of the spore
HAGICGNN_02332 7e-136 yiiD K acetyltransferase
HAGICGNN_02334 3e-235 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAGICGNN_02335 4.2e-09 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HAGICGNN_02336 3.6e-109 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HAGICGNN_02337 6.5e-251 yodQ 3.5.1.16 E Acetylornithine deacetylase
HAGICGNN_02338 9.4e-139 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HAGICGNN_02339 8.8e-270 kamA 5.4.3.2 E lysine 2,3-aminomutase
HAGICGNN_02340 5e-44 yokU S YokU-like protein, putative antitoxin
HAGICGNN_02341 9.1e-36 yozE S Belongs to the UPF0346 family
HAGICGNN_02342 1.6e-123 yodN
HAGICGNN_02344 6.3e-24 yozD S YozD-like protein
HAGICGNN_02345 3.1e-102 yodM 3.6.1.27 I Acid phosphatase homologues
HAGICGNN_02346 1.4e-53 yodL S YodL-like
HAGICGNN_02347 1e-07
HAGICGNN_02348 1.6e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HAGICGNN_02349 2.5e-131 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HAGICGNN_02350 1.7e-22 yodI
HAGICGNN_02351 3.1e-122 yodH Q Methyltransferase
HAGICGNN_02352 6.7e-246 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HAGICGNN_02353 3.4e-264 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAGICGNN_02354 1.2e-26 S Protein of unknown function (DUF3311)
HAGICGNN_02355 3e-162 yodE E COG0346 Lactoylglutathione lyase and related lyases
HAGICGNN_02356 5.9e-106 mhqD S Carboxylesterase
HAGICGNN_02357 2e-106 yodC C nitroreductase
HAGICGNN_02358 7e-53 yodB K transcriptional
HAGICGNN_02359 2.8e-61 yodA S tautomerase
HAGICGNN_02360 1.8e-128 gntP EG COG2610 H gluconate symporter and related permeases
HAGICGNN_02361 2.7e-56 gntP EG COG2610 H gluconate symporter and related permeases
HAGICGNN_02362 2.2e-08
HAGICGNN_02363 1.7e-65 yozR S COG0071 Molecular chaperone (small heat shock protein)
HAGICGNN_02364 1.1e-153 rarD S -transporter
HAGICGNN_02365 4.4e-40
HAGICGNN_02366 6.3e-60 yojF S Protein of unknown function (DUF1806)
HAGICGNN_02367 4.5e-123 yojG S deacetylase
HAGICGNN_02368 2.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAGICGNN_02369 2.8e-233 norM V Multidrug efflux pump
HAGICGNN_02371 9.2e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAGICGNN_02372 1.3e-216 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HAGICGNN_02373 5.3e-186 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HAGICGNN_02374 2e-103 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HAGICGNN_02375 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
HAGICGNN_02376 0.0 yojO P Von Willebrand factor
HAGICGNN_02377 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HAGICGNN_02378 2e-177 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HAGICGNN_02379 4.6e-161 yocS S -transporter
HAGICGNN_02380 1.4e-224 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HAGICGNN_02381 2.9e-159 sodA 1.15.1.1 P Superoxide dismutase
HAGICGNN_02382 4.1e-276 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HAGICGNN_02383 1.2e-285 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HAGICGNN_02384 8e-31 yozC
HAGICGNN_02385 1.6e-55 yozO S Bacterial PH domain
HAGICGNN_02386 1.5e-78 dksA T general stress protein
HAGICGNN_02387 2.8e-111 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAGICGNN_02388 0.0 recQ 3.6.4.12 L DNA helicase
HAGICGNN_02389 3.6e-109 yocH CBM50 M COG1388 FOG LysM repeat
HAGICGNN_02390 1.9e-104 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_02391 4.9e-191 desK 2.7.13.3 T Histidine kinase
HAGICGNN_02392 1.2e-194 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HAGICGNN_02393 7.6e-180 yocD 3.4.17.13 V peptidase S66
HAGICGNN_02394 3.7e-90 yocC
HAGICGNN_02395 2.8e-132
HAGICGNN_02396 7.3e-92 yozB S membrane
HAGICGNN_02397 7.8e-115 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HAGICGNN_02398 1.2e-49 czrA K transcriptional
HAGICGNN_02399 4e-85 yobW
HAGICGNN_02400 8.4e-160 yobV K WYL domain
HAGICGNN_02401 1.3e-76 yobU K Bacterial transcription activator, effector binding domain
HAGICGNN_02402 2.3e-125 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HAGICGNN_02403 2.7e-84 yobS K Transcriptional regulator
HAGICGNN_02404 3.5e-124 yobR 2.3.1.1 J FR47-like protein
HAGICGNN_02405 1.7e-131 yobQ K helix_turn_helix, arabinose operon control protein
HAGICGNN_02406 1.9e-50 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HAGICGNN_02407 3e-291 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HAGICGNN_02408 7.4e-85 S SMI1-KNR4 cell-wall
HAGICGNN_02409 9e-106 yobJ
HAGICGNN_02411 1.6e-52 S YolD-like protein
HAGICGNN_02412 6.4e-176 S impB/mucB/samB family C-terminal domain
HAGICGNN_02413 4.7e-29 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HAGICGNN_02414 3.4e-18
HAGICGNN_02416 3.8e-90 S aspartate phosphatase
HAGICGNN_02418 5.7e-29
HAGICGNN_02421 4.8e-38 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F deoxyuridine 5'-triphosphate nucleotidohydrolase
HAGICGNN_02422 1.9e-08 S Hypothetical protein (DUF2513)
HAGICGNN_02423 1.2e-08
HAGICGNN_02424 1.2e-32 S DNA ligase (ATP) activity
HAGICGNN_02425 1.6e-109 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HAGICGNN_02426 2.4e-176 adhP 1.1.1.1 C alcohol dehydrogenase
HAGICGNN_02427 8.1e-247 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HAGICGNN_02428 3.6e-55 S Uncharacterized protein conserved in bacteria (DUF2200)
HAGICGNN_02430 6.6e-183 S aspartate phosphatase
HAGICGNN_02431 1.7e-103 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HAGICGNN_02432 6.3e-72 S CAAX protease self-immunity
HAGICGNN_02434 3.4e-155 yijE EG EamA-like transporter family
HAGICGNN_02435 1.4e-148 yoaU K LysR substrate binding domain
HAGICGNN_02436 9.1e-139 yoaT S Protein of unknown function (DUF817)
HAGICGNN_02437 1.3e-29 yozG K Transcriptional regulator
HAGICGNN_02438 3.6e-66 yoaS S Protein of unknown function (DUF2975)
HAGICGNN_02439 3.7e-152 yoaR V vancomycin resistance protein
HAGICGNN_02440 2.3e-66
HAGICGNN_02442 1.8e-57 yoaQ S Evidence 4 Homologs of previously reported genes of
HAGICGNN_02444 7.6e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HAGICGNN_02447 3.3e-121 yoqW S Belongs to the SOS response-associated peptidase family
HAGICGNN_02448 9.8e-47 yoaW
HAGICGNN_02449 5.4e-128 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_02450 8.6e-190 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HAGICGNN_02451 2.7e-103 yoaK S Membrane
HAGICGNN_02453 1.6e-123 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HAGICGNN_02454 1.4e-254 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HAGICGNN_02455 1e-163 mcpU NT methyl-accepting chemotaxis protein
HAGICGNN_02456 3.3e-38 S Protein of unknown function (DUF4025)
HAGICGNN_02457 1e-12
HAGICGNN_02458 1.4e-07 ywlA S Uncharacterised protein family (UPF0715)
HAGICGNN_02459 4.8e-16 purR K Transcriptional regulator
HAGICGNN_02460 1.7e-50 S Oxidoreductase family, C-terminal alpha/beta domain
HAGICGNN_02461 6.3e-37 yoaF
HAGICGNN_02462 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAGICGNN_02463 1.8e-176 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAGICGNN_02464 5.4e-254 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HAGICGNN_02465 2.7e-230 yoaB EGP Major facilitator Superfamily
HAGICGNN_02466 1.9e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_02467 1.1e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
HAGICGNN_02468 1.4e-93 V ABC-2 type transporter
HAGICGNN_02469 2.6e-127 V ABC-2 family transporter protein
HAGICGNN_02470 6.4e-38 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAGICGNN_02471 1e-62 yoxB
HAGICGNN_02472 7.7e-38 yoxB
HAGICGNN_02473 1.1e-36 yoxC S Bacterial protein of unknown function (DUF948)
HAGICGNN_02474 3.8e-120 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_02475 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HAGICGNN_02476 6.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HAGICGNN_02477 9e-193 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HAGICGNN_02478 8.1e-152 gltC K Transcriptional regulator
HAGICGNN_02479 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HAGICGNN_02480 1.8e-289 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HAGICGNN_02481 1.6e-169 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HAGICGNN_02482 4.4e-139 gltR1 K Transcriptional regulator
HAGICGNN_02483 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HAGICGNN_02484 1.5e-33 yoeD G Helix-turn-helix domain
HAGICGNN_02485 9.4e-95 L Integrase
HAGICGNN_02487 2.2e-96 yoeB S IseA DL-endopeptidase inhibitor
HAGICGNN_02488 6e-239 yoeA V MATE efflux family protein
HAGICGNN_02489 1.5e-175 yoxA 5.1.3.3 G Aldose 1-epimerase
HAGICGNN_02490 2.1e-245 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HAGICGNN_02491 4.7e-91 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_02492 3.4e-39 S COG NOG14552 non supervised orthologous group
HAGICGNN_02497 2e-08
HAGICGNN_02502 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAGICGNN_02503 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HAGICGNN_02504 1.8e-37 yaaB S Domain of unknown function (DUF370)
HAGICGNN_02505 8.6e-204 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HAGICGNN_02506 6.9e-33 yaaA S S4 domain
HAGICGNN_02507 4e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HAGICGNN_02508 3e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HAGICGNN_02509 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HAGICGNN_02510 5.1e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HAGICGNN_02511 1.3e-100 jag S single-stranded nucleic acid binding R3H
HAGICGNN_02512 5.4e-248 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HAGICGNN_02513 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HAGICGNN_02514 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HAGICGNN_02515 1.4e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HAGICGNN_02516 1.1e-64 S Bacterial PH domain
HAGICGNN_02517 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HAGICGNN_02518 3.7e-146 spo0J K Belongs to the ParB family
HAGICGNN_02519 2.4e-107 yyaC S Sporulation protein YyaC
HAGICGNN_02520 8.2e-177 yyaD S Membrane
HAGICGNN_02521 9.6e-32 yyzM S protein conserved in bacteria
HAGICGNN_02522 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAGICGNN_02523 1.3e-199 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HAGICGNN_02524 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
HAGICGNN_02525 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HAGICGNN_02526 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HAGICGNN_02527 9.6e-138 xth 3.1.11.2 L exodeoxyribonuclease III
HAGICGNN_02528 4.4e-169 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HAGICGNN_02529 1.9e-62 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAGICGNN_02530 5.4e-90 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HAGICGNN_02531 3e-235 EGP Major facilitator superfamily
HAGICGNN_02532 5.8e-158 yyaK S CAAX protease self-immunity
HAGICGNN_02533 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HAGICGNN_02534 4.8e-34 V HNH nucleases
HAGICGNN_02535 2.9e-90 3.6.3.55 P tungstate ion transport
HAGICGNN_02536 8.9e-41 S Abortive infection C-terminus
HAGICGNN_02537 9.8e-52 L Restriction endonuclease
HAGICGNN_02538 8.4e-64 ynaF
HAGICGNN_02539 1.9e-67
HAGICGNN_02540 2.5e-31 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HAGICGNN_02541 7e-80 yosT L Bacterial transcription activator, effector binding domain
HAGICGNN_02542 1.4e-29 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HAGICGNN_02543 1.2e-79 T COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
HAGICGNN_02544 3e-155 1.1.1.219 M NAD dependent epimerase dehydratase family
HAGICGNN_02545 1.1e-16 yyaL O Highly conserved protein containing a thioredoxin domain
HAGICGNN_02546 9.4e-156 yyaM EG EamA-like transporter family
HAGICGNN_02547 1.9e-60 yyaN K MerR HTH family regulatory protein
HAGICGNN_02548 1e-89 yyaS S Membrane
HAGICGNN_02549 8.2e-62 yjcF S Acetyltransferase (GNAT) domain
HAGICGNN_02550 1.1e-72 yybA 2.3.1.57 K transcriptional
HAGICGNN_02551 2.3e-119 S Metallo-beta-lactamase superfamily
HAGICGNN_02552 3.5e-142 bla 3.5.2.6 V beta-lactamase
HAGICGNN_02553 1.4e-110 yybG S Pentapeptide repeat-containing protein
HAGICGNN_02554 5.4e-60 yybH S SnoaL-like domain
HAGICGNN_02555 2.1e-119
HAGICGNN_02556 4.1e-237 yybO G COG0477 Permeases of the major facilitator superfamily
HAGICGNN_02558 6.1e-68
HAGICGNN_02559 4.3e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HAGICGNN_02560 3e-68 ydeP3 K Transcriptional regulator
HAGICGNN_02561 2.7e-77 cotF M Spore coat protein
HAGICGNN_02563 8.4e-152 yybS S membrane
HAGICGNN_02564 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HAGICGNN_02565 7.1e-72 rplI J binds to the 23S rRNA
HAGICGNN_02566 1.2e-304 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HAGICGNN_02567 1.8e-194 yeaN P COG2807 Cyanate permease
HAGICGNN_02568 1.8e-13 yycC K YycC-like protein
HAGICGNN_02570 2.1e-28 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HAGICGNN_02571 6.8e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HAGICGNN_02572 1.2e-68 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAGICGNN_02573 3.9e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HAGICGNN_02578 3.3e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_02579 0.0 vicK 2.7.13.3 T Histidine kinase
HAGICGNN_02580 8.3e-249 yycH S protein conserved in bacteria
HAGICGNN_02581 1e-148 yycI S protein conserved in bacteria
HAGICGNN_02582 1.6e-148 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HAGICGNN_02583 9.3e-212 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAGICGNN_02584 1.1e-253 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HAGICGNN_02585 8.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HAGICGNN_02586 2.1e-258 rocE E amino acid
HAGICGNN_02587 2.6e-166 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HAGICGNN_02589 8.5e-188 S aspartate phosphatase
HAGICGNN_02590 6.2e-79 yycN 2.3.1.128 K Acetyltransferase
HAGICGNN_02591 2e-124 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HAGICGNN_02592 1.1e-196 yycP
HAGICGNN_02595 7.4e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HAGICGNN_02596 2.3e-61
HAGICGNN_02597 1.1e-09 S YyzF-like protein
HAGICGNN_02598 8.9e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HAGICGNN_02599 6.9e-156 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HAGICGNN_02600 3.3e-13 U Protein of unknown function DUF262
HAGICGNN_02604 2.6e-134 S MvaI/BcnI restriction endonuclease family
HAGICGNN_02605 6.2e-22 3.1.3.16 S Protein of unknown function (DUF1643)
HAGICGNN_02606 6.9e-15
HAGICGNN_02608 4.6e-81 S Phage plasmid primase, P4 family
HAGICGNN_02609 1.3e-28 L Recombinase
HAGICGNN_02610 1.1e-40 L Recombinase
HAGICGNN_02611 6.3e-32 K Helix-turn-helix XRE-family like proteins
HAGICGNN_02612 3e-36
HAGICGNN_02613 1e-127 V ATPases associated with a variety of cellular activities
HAGICGNN_02614 9.2e-98
HAGICGNN_02615 1.9e-154 ydjC S Abhydrolase domain containing 18
HAGICGNN_02616 3.8e-68 prsK T PFAM ATP-binding region ATPase domain protein
HAGICGNN_02617 4.8e-41 T cheY-homologous receiver domain
HAGICGNN_02618 1.1e-08 S Lantibiotic alpha
HAGICGNN_02620 8.7e-179 lanM V type 2 lantibiotic biosynthesis protein LanM
HAGICGNN_02621 4.1e-141 3.6.3.27 V ABC transporter
HAGICGNN_02622 5.6e-167 lanM V Lanthionine synthetase C family protein
HAGICGNN_02623 1.1e-70 1.6.5.5 C alcohol dehydrogenase
HAGICGNN_02624 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HAGICGNN_02625 3.9e-11
HAGICGNN_02626 8.3e-179 S Radical SAM superfamily
HAGICGNN_02627 8.7e-131 yydH O Peptidase M50
HAGICGNN_02628 4.7e-106 prrC P ABC transporter
HAGICGNN_02629 2.6e-116 S ABC-2 family transporter protein
HAGICGNN_02630 8.4e-12
HAGICGNN_02631 4.3e-18
HAGICGNN_02632 4.3e-189 wgaE S Polysaccharide pyruvyl transferase
HAGICGNN_02633 8.3e-282 ahpF O Alkyl hydroperoxide reductase
HAGICGNN_02634 5.1e-104 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HAGICGNN_02636 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HAGICGNN_02637 3.6e-228 gntP EG COG2610 H gluconate symporter and related permeases
HAGICGNN_02638 2.7e-296 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HAGICGNN_02639 2.2e-123 gntR K transcriptional
HAGICGNN_02640 7.3e-190 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HAGICGNN_02641 5e-190 yxaB GM Polysaccharide pyruvyl transferase
HAGICGNN_02642 6.7e-210 nhaS2 P Sodium/hydrogen exchanger family
HAGICGNN_02643 1.1e-113 yxaC M effector of murein hydrolase
HAGICGNN_02644 1.3e-45 S LrgA family
HAGICGNN_02645 1.4e-65 yxaD K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_02646 8.1e-183 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_02647 8.1e-97 yxaF K Transcriptional regulator
HAGICGNN_02648 3.4e-183 yxaG 1.13.11.24 S AraC-like ligand binding domain
HAGICGNN_02649 3.7e-208 P Protein of unknown function (DUF418)
HAGICGNN_02650 5.8e-74 yxaI S membrane protein domain
HAGICGNN_02651 1.9e-58 S Family of unknown function (DUF5391)
HAGICGNN_02652 5.1e-80 S PQQ-like domain
HAGICGNN_02653 6.2e-18 yxaI S membrane protein domain
HAGICGNN_02654 1.1e-242 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HAGICGNN_02655 2.1e-176 yxbF K Bacterial regulatory proteins, tetR family
HAGICGNN_02658 1.8e-145 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_02660 0.0 htpG O Molecular chaperone. Has ATPase activity
HAGICGNN_02661 1.7e-238 csbC EGP Major facilitator Superfamily
HAGICGNN_02662 6.8e-79 T HPP family
HAGICGNN_02663 1.7e-91 S CGNR zinc finger
HAGICGNN_02664 5.7e-49 yxcD S Protein of unknown function (DUF2653)
HAGICGNN_02666 1.9e-172 iolS C Aldo keto reductase
HAGICGNN_02667 1.2e-137 iolR K COG1349 Transcriptional regulators of sugar metabolism
HAGICGNN_02668 3.7e-279 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAGICGNN_02669 4.4e-149 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HAGICGNN_02670 6.7e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HAGICGNN_02671 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HAGICGNN_02672 1.2e-168 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HAGICGNN_02673 4.4e-231 iolF EGP Major facilitator Superfamily
HAGICGNN_02674 8.9e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HAGICGNN_02675 7.3e-166 iolH G Xylose isomerase-like TIM barrel
HAGICGNN_02676 1.4e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HAGICGNN_02677 7.6e-139 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HAGICGNN_02678 3.5e-169 fhuD P ABC transporter
HAGICGNN_02679 3.1e-10
HAGICGNN_02680 2.7e-47
HAGICGNN_02681 1e-12 yxeD
HAGICGNN_02685 7.8e-146 yidA S hydrolases of the HAD superfamily
HAGICGNN_02686 7.3e-250 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAGICGNN_02687 3.9e-87 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_02688 1.9e-128 yxeM M Belongs to the bacterial solute-binding protein 3 family
HAGICGNN_02689 8.6e-114 yxeN P COG0765 ABC-type amino acid transport system, permease component
HAGICGNN_02690 2.5e-130 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HAGICGNN_02691 2.7e-208 yxeP 3.5.1.47 E hydrolase activity
HAGICGNN_02692 1e-235 yxeQ S MmgE/PrpD family
HAGICGNN_02693 1.9e-187 eutH E Ethanolamine utilisation protein, EutH
HAGICGNN_02694 3.7e-143 yxxB S Domain of Unknown Function (DUF1206)
HAGICGNN_02695 5.6e-172 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HAGICGNN_02696 3.2e-113 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HAGICGNN_02697 3.9e-194 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAGICGNN_02698 1e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HAGICGNN_02699 1.9e-251 lysP E amino acid
HAGICGNN_02700 4e-173 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HAGICGNN_02701 3.3e-228 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HAGICGNN_02702 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HAGICGNN_02703 1.2e-277 hutH 4.3.1.3 E Histidine ammonia-lyase
HAGICGNN_02704 9.6e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HAGICGNN_02705 5e-273 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HAGICGNN_02706 2.1e-21 S Domain of unknown function (DUF5082)
HAGICGNN_02707 2e-37 yxiC S Family of unknown function (DUF5344)
HAGICGNN_02708 2.8e-197 S nuclease activity
HAGICGNN_02709 6.8e-44
HAGICGNN_02710 3e-45
HAGICGNN_02713 3.3e-33 S Uncharacterized protein conserved in bacteria (DUF2247)
HAGICGNN_02714 1.8e-307 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_02715 8.8e-270 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HAGICGNN_02716 1.2e-68 yxiE T Belongs to the universal stress protein A family
HAGICGNN_02717 2.7e-121 1.14.11.45 E 2OG-Fe dioxygenase
HAGICGNN_02718 6.3e-126 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_02719 7.3e-156 yxxF EG EamA-like transporter family
HAGICGNN_02721 4.1e-33
HAGICGNN_02722 2.7e-36
HAGICGNN_02723 7.4e-68 yxiG
HAGICGNN_02724 1.2e-136
HAGICGNN_02725 7.9e-93 yxiI S Protein of unknown function (DUF2716)
HAGICGNN_02726 3.3e-37 yxiJ S YxiJ-like protein
HAGICGNN_02729 4.5e-34 yxxF EG EamA-like transporter family
HAGICGNN_02731 6.5e-43 S Protein of unknown function (DUF2812)
HAGICGNN_02732 1.5e-50 padR K Transcriptional regulator PadR-like family
HAGICGNN_02733 2.6e-203 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HAGICGNN_02734 1.6e-258 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HAGICGNN_02735 1e-224 yxiO S COG2270 Permeases of the major facilitator superfamily
HAGICGNN_02736 1e-90
HAGICGNN_02737 1.9e-147 licT K transcriptional antiterminator
HAGICGNN_02738 1e-241 bglF G phosphotransferase system
HAGICGNN_02739 9.2e-259 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HAGICGNN_02740 4e-161
HAGICGNN_02741 3.2e-218 citH C Citrate transporter
HAGICGNN_02742 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HAGICGNN_02743 9.3e-44 yxiS
HAGICGNN_02744 7.7e-107 T Domain of unknown function (DUF4163)
HAGICGNN_02745 2.7e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAGICGNN_02746 2.9e-143 rlmA 2.1.1.187 Q Methyltransferase domain
HAGICGNN_02747 8.6e-241 yxjC EG COG2610 H gluconate symporter and related permeases
HAGICGNN_02748 5.1e-125 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HAGICGNN_02749 6e-112 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HAGICGNN_02750 1.3e-129 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HAGICGNN_02751 2.9e-215 yxjG 2.1.1.14 E Methionine synthase
HAGICGNN_02752 1.6e-213 yxjG 2.1.1.14 E Methionine synthase
HAGICGNN_02753 1.3e-66 yxjI S LURP-one-related
HAGICGNN_02755 1e-226 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HAGICGNN_02756 6.2e-109 K helix_turn_helix, Lux Regulon
HAGICGNN_02757 5.1e-165 yxjM T Signal transduction histidine kinase
HAGICGNN_02758 1.1e-75 S Protein of unknown function (DUF1453)
HAGICGNN_02759 8.1e-157 yxjO K LysR substrate binding domain
HAGICGNN_02760 4.3e-86 yxkA S Phosphatidylethanolamine-binding protein
HAGICGNN_02761 7.4e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HAGICGNN_02762 2.3e-76 yxkC S Domain of unknown function (DUF4352)
HAGICGNN_02763 1.4e-145 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HAGICGNN_02764 1.7e-260 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAGICGNN_02765 3e-146 lrp QT PucR C-terminal helix-turn-helix domain
HAGICGNN_02766 2.7e-202 msmK P Belongs to the ABC transporter superfamily
HAGICGNN_02767 2.8e-110 P transporter
HAGICGNN_02768 6.6e-148 yxkH G Polysaccharide deacetylase
HAGICGNN_02770 4.7e-286 3.4.24.84 O Peptidase family M48
HAGICGNN_02771 2.4e-224 cimH C COG3493 Na citrate symporter
HAGICGNN_02772 1.3e-265 cydA 1.10.3.14 C oxidase, subunit
HAGICGNN_02773 1.9e-186 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HAGICGNN_02774 7.3e-303 cydD V ATP-binding
HAGICGNN_02775 8.4e-307 cydD V ATP-binding protein
HAGICGNN_02776 7e-150 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HAGICGNN_02777 2.8e-252 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HAGICGNN_02778 5.4e-87 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_02779 4e-37 yxlC S Family of unknown function (DUF5345)
HAGICGNN_02780 3.2e-27
HAGICGNN_02781 2.9e-27 yxlE S Phospholipase_D-nuclease N-terminal
HAGICGNN_02782 2.9e-154 yxlF V ABC transporter, ATP-binding protein
HAGICGNN_02783 5.4e-128 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAGICGNN_02784 6.2e-200 yxlH EGP Major facilitator Superfamily
HAGICGNN_02785 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HAGICGNN_02786 4e-107 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HAGICGNN_02787 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HAGICGNN_02788 5.2e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HAGICGNN_02789 1.6e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAGICGNN_02790 7.4e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HAGICGNN_02791 5.6e-250 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HAGICGNN_02792 1.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HAGICGNN_02793 3.5e-132 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_02794 2.9e-226 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HAGICGNN_02795 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_02796 2.2e-229 dltB M membrane protein involved in D-alanine export
HAGICGNN_02797 2.2e-279 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_02798 1.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HAGICGNN_02799 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HAGICGNN_02800 5.8e-129 ynfM EGP Major facilitator Superfamily
HAGICGNN_02801 1.4e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HAGICGNN_02802 1.6e-93 K Helix-turn-helix XRE-family like proteins
HAGICGNN_02803 1.3e-238 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HAGICGNN_02804 3.8e-216 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HAGICGNN_02805 1.2e-78 ywaE K Transcriptional regulator
HAGICGNN_02806 1.1e-114 ywaF S Integral membrane protein
HAGICGNN_02807 9.1e-161 gspA M General stress
HAGICGNN_02808 1.6e-149 sacY K transcriptional antiterminator
HAGICGNN_02809 4.2e-231 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_02810 3.1e-257 epr 3.4.21.62 O Belongs to the peptidase S8 family
HAGICGNN_02811 3.6e-241 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAGICGNN_02812 2.2e-66 ywbC 4.4.1.5 E glyoxalase
HAGICGNN_02813 5.4e-212 ywbD 2.1.1.191 J Methyltransferase
HAGICGNN_02814 4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HAGICGNN_02815 6.2e-208 ywbF EGP Major facilitator Superfamily
HAGICGNN_02816 1.2e-125
HAGICGNN_02819 3.7e-98 V ATPases associated with a variety of cellular activities
HAGICGNN_02820 6.4e-109 ywbG M effector of murein hydrolase
HAGICGNN_02821 5.5e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HAGICGNN_02822 1.2e-150 ywbI K Transcriptional regulator
HAGICGNN_02823 1.9e-136 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HAGICGNN_02824 1.2e-107 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HAGICGNN_02825 5.5e-243 P COG0672 High-affinity Fe2 Pb2 permease
HAGICGNN_02826 1.4e-156 ycdO P periplasmic lipoprotein involved in iron transport
HAGICGNN_02827 1.4e-218 ywbN P Dyp-type peroxidase family protein
HAGICGNN_02828 9.1e-107 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HAGICGNN_02829 2.4e-265 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAGICGNN_02830 6.6e-45 ywcB S Protein of unknown function, DUF485
HAGICGNN_02832 7.5e-102 ywcC K transcriptional regulator
HAGICGNN_02833 1.4e-58 gtcA S GtrA-like protein
HAGICGNN_02834 2.5e-217 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HAGICGNN_02835 7.1e-289 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HAGICGNN_02836 2.2e-35 ywzA S membrane
HAGICGNN_02837 4e-176 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HAGICGNN_02838 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HAGICGNN_02839 3.6e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HAGICGNN_02840 4.5e-59 qoxD 1.10.3.12 C quinol oxidase, subunit
HAGICGNN_02841 1e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
HAGICGNN_02842 6.4e-189 rodA D Belongs to the SEDS family
HAGICGNN_02843 7.7e-132 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HAGICGNN_02844 1.8e-176 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAGICGNN_02845 3.2e-53 L COG2963 Transposase and inactivated derivatives
HAGICGNN_02849 2e-08
HAGICGNN_02852 5.1e-96 L Integrase core domain
HAGICGNN_02853 9.4e-161 ygxA S Nucleotidyltransferase-like
HAGICGNN_02854 8.1e-55 ygzB S UPF0295 protein
HAGICGNN_02855 4e-80 perR P Belongs to the Fur family
HAGICGNN_02856 1.2e-85 bcp 1.11.1.15 O Peroxiredoxin
HAGICGNN_02857 5.4e-242 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HAGICGNN_02858 8.1e-178 ygaE S Membrane
HAGICGNN_02859 3.3e-295 ygaD V ABC transporter
HAGICGNN_02860 3.7e-104 ygaC J Belongs to the UPF0374 family
HAGICGNN_02861 5.6e-37 ygaB S YgaB-like protein
HAGICGNN_02862 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HAGICGNN_02863 6.4e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_02864 2e-35 yfhS
HAGICGNN_02865 7.8e-205 mutY L A G-specific
HAGICGNN_02866 9.7e-183 yfhP S membrane-bound metal-dependent
HAGICGNN_02867 0.0 yfhO S Bacterial membrane protein YfhO
HAGICGNN_02868 2.9e-179 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HAGICGNN_02869 1e-159 yfhM S Alpha beta hydrolase
HAGICGNN_02870 1.6e-36 yfhL S SdpI/YhfL protein family
HAGICGNN_02871 5.1e-82 batE T Bacterial SH3 domain homologues
HAGICGNN_02872 1.6e-42 yfhJ S WVELL protein
HAGICGNN_02873 1.4e-19 sspK S reproduction
HAGICGNN_02874 5.8e-206 yfhI EGP Major facilitator Superfamily
HAGICGNN_02875 2.4e-45 yfhH S Protein of unknown function (DUF1811)
HAGICGNN_02876 2.3e-134 recX 2.4.1.337 GT4 S Modulates RecA activity
HAGICGNN_02877 1.8e-162 yfhF S nucleoside-diphosphate sugar epimerase
HAGICGNN_02879 5.2e-24 yfhD S YfhD-like protein
HAGICGNN_02880 1.3e-102 yfhC C nitroreductase
HAGICGNN_02881 1.2e-152 yfhB 5.3.3.17 S PhzF family
HAGICGNN_02882 4.3e-173 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_02883 1.8e-168 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_02884 8.2e-174 yfiY P ABC transporter substrate-binding protein
HAGICGNN_02885 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HAGICGNN_02886 4.1e-78 yfiV K transcriptional
HAGICGNN_02887 2.5e-278 yfiU EGP Major facilitator Superfamily
HAGICGNN_02888 5.6e-92 yfiT S Belongs to the metal hydrolase YfiT family
HAGICGNN_02889 1.5e-184 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HAGICGNN_02890 6.2e-74 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HAGICGNN_02891 1.4e-93 padR K transcriptional
HAGICGNN_02892 2.7e-69 J Acetyltransferase (GNAT) domain
HAGICGNN_02893 2.5e-185 V COG0842 ABC-type multidrug transport system, permease component
HAGICGNN_02894 6.9e-191 V ABC-2 family transporter protein
HAGICGNN_02895 1.5e-164 V ABC transporter, ATP-binding protein
HAGICGNN_02896 5.8e-107 KT LuxR family transcriptional regulator
HAGICGNN_02897 4.1e-201 yxjM T Histidine kinase
HAGICGNN_02899 1.6e-152 yfiE 1.13.11.2 S glyoxalase
HAGICGNN_02900 1.1e-60 mhqP S DoxX
HAGICGNN_02901 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HAGICGNN_02902 3.5e-297 yfiB3 V ABC transporter
HAGICGNN_02903 1.1e-289 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_02904 4.3e-138 glvR K Helix-turn-helix domain, rpiR family
HAGICGNN_02905 2.5e-258 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HAGICGNN_02906 1.4e-42 yfjA S Belongs to the WXG100 family
HAGICGNN_02907 5.4e-183 yfjB
HAGICGNN_02908 5.5e-141 yfjC
HAGICGNN_02909 4.9e-99 yfjD S Family of unknown function (DUF5381)
HAGICGNN_02910 7.7e-81 S Family of unknown function (DUF5381)
HAGICGNN_02911 1.7e-54 yfjF S UPF0060 membrane protein
HAGICGNN_02912 1.1e-23 sspH S Belongs to the SspH family
HAGICGNN_02913 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HAGICGNN_02914 1.9e-248 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HAGICGNN_02915 7.9e-195 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HAGICGNN_02916 1.8e-187 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HAGICGNN_02917 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HAGICGNN_02918 4.6e-30 yfjL
HAGICGNN_02919 2.4e-80 yfjM S Psort location Cytoplasmic, score
HAGICGNN_02920 9.1e-75 ydaF_2 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAGICGNN_02921 7.9e-185 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HAGICGNN_02922 6.9e-165 D nuclear chromosome segregation
HAGICGNN_02923 7e-77
HAGICGNN_02924 7.9e-39 S FRG domain
HAGICGNN_02925 4.5e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAGICGNN_02926 8.6e-159 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HAGICGNN_02927 3.4e-180 corA P Mediates influx of magnesium ions
HAGICGNN_02928 1.9e-142 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HAGICGNN_02929 4.2e-152 pdaA G deacetylase
HAGICGNN_02930 1.1e-26 yfjT
HAGICGNN_02931 3.4e-216 yfkA S YfkB-like domain
HAGICGNN_02932 4.3e-147 yfkC M Mechanosensitive ion channel
HAGICGNN_02933 1.6e-143 yfkD S YfkD-like protein
HAGICGNN_02934 5.9e-178 cax P COG0387 Ca2 H antiporter
HAGICGNN_02935 1.5e-214 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HAGICGNN_02937 3.5e-141 yihY S Belongs to the UPF0761 family
HAGICGNN_02938 6e-49 yfkI S gas vesicle protein
HAGICGNN_02939 1.3e-81 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HAGICGNN_02940 3e-28 yfkK S Belongs to the UPF0435 family
HAGICGNN_02941 2.4e-196 ydiM EGP Major facilitator Superfamily
HAGICGNN_02942 6.2e-88 yfkM 3.5.1.124 S protease
HAGICGNN_02943 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HAGICGNN_02944 5.8e-123 yfkO C nitroreductase
HAGICGNN_02945 5.3e-130 treR K transcriptional
HAGICGNN_02946 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HAGICGNN_02947 1.7e-252 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_02948 8.4e-274 yfkQ EG Spore germination protein
HAGICGNN_02949 5.3e-188 yfkR S spore germination
HAGICGNN_02951 8.4e-180 E Spore germination protein
HAGICGNN_02952 8.9e-246 agcS_1 E Sodium alanine symporter
HAGICGNN_02953 5.2e-63 yhdN S Domain of unknown function (DUF1992)
HAGICGNN_02954 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HAGICGNN_02955 4.5e-247 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HAGICGNN_02956 1.6e-137 map 3.4.11.18 E Methionine aminopeptidase
HAGICGNN_02957 4.7e-46 yflH S Protein of unknown function (DUF3243)
HAGICGNN_02958 1e-17 yflI
HAGICGNN_02959 8.9e-18 yflJ S Protein of unknown function (DUF2639)
HAGICGNN_02960 1.9e-113 yflK S protein conserved in bacteria
HAGICGNN_02961 2.3e-41 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HAGICGNN_02962 3.7e-208 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HAGICGNN_02963 2e-146 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HAGICGNN_02964 1.2e-225 citM C Citrate transporter
HAGICGNN_02965 5.2e-165 yflP S Tripartite tricarboxylate transporter family receptor
HAGICGNN_02966 8.1e-112 citT T response regulator
HAGICGNN_02967 2.8e-267 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HAGICGNN_02968 1.5e-232 yflS P Sodium:sulfate symporter transmembrane region
HAGICGNN_02969 5.3e-234 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HAGICGNN_02970 9.3e-56 yflT S Heat induced stress protein YflT
HAGICGNN_02971 6.9e-25 S Protein of unknown function (DUF3212)
HAGICGNN_02972 2.9e-160 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HAGICGNN_02973 1.9e-165 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_02974 8.1e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_02975 1.7e-148 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HAGICGNN_02976 3.2e-181 yfmJ S N-terminal domain of oxidoreductase
HAGICGNN_02977 1.4e-67 yfmK 2.3.1.128 K acetyltransferase
HAGICGNN_02978 3.6e-197 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HAGICGNN_02979 1.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAGICGNN_02980 6.3e-73
HAGICGNN_02981 8.9e-207 yfmO EGP Major facilitator Superfamily
HAGICGNN_02982 2.8e-70 yfmP K transcriptional
HAGICGNN_02983 1e-67 yfmQ S Uncharacterised protein from bacillus cereus group
HAGICGNN_02984 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HAGICGNN_02985 1.7e-111 yfmS NT chemotaxis protein
HAGICGNN_02986 1e-276 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAGICGNN_02987 6.7e-238 yfnA E amino acid
HAGICGNN_02988 4.9e-120 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HAGICGNN_02989 4.7e-203 fsr P COG0477 Permeases of the major facilitator superfamily
HAGICGNN_02990 1.8e-186 yfnD M Nucleotide-diphospho-sugar transferase
HAGICGNN_02991 8.7e-215 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HAGICGNN_02992 1.6e-176 yfnF M Nucleotide-diphospho-sugar transferase
HAGICGNN_02993 1.6e-171 yfnG 4.2.1.45 M dehydratase
HAGICGNN_02994 6.2e-145 rfbF 2.7.7.33 JM Nucleotidyl transferase
HAGICGNN_02995 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HAGICGNN_02996 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HAGICGNN_02997 1.5e-197 yetN S Protein of unknown function (DUF3900)
HAGICGNN_02998 5e-204 yetM CH FAD binding domain
HAGICGNN_02999 1.2e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_03000 2.5e-156 yetK EG EamA-like transporter family
HAGICGNN_03001 9.1e-105 yetJ S Belongs to the BI1 family
HAGICGNN_03002 2.6e-19 yezD S Uncharacterized small protein (DUF2292)
HAGICGNN_03003 6.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HAGICGNN_03004 1.5e-36
HAGICGNN_03005 1.3e-60 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HAGICGNN_03006 5.5e-50 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HAGICGNN_03007 4e-106 yetF S membrane
HAGICGNN_03008 1.2e-231 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HAGICGNN_03009 4.7e-160 lplC G Binding-protein-dependent transport system inner membrane component
HAGICGNN_03010 4.2e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HAGICGNN_03011 4e-284 lplA G Bacterial extracellular solute-binding protein
HAGICGNN_03012 0.0 yetA
HAGICGNN_03013 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HAGICGNN_03014 6.3e-122 yesY E GDSL-like Lipase/Acylhydrolase
HAGICGNN_03015 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HAGICGNN_03016 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HAGICGNN_03017 2.5e-107 yesV S Protein of unknown function, DUF624
HAGICGNN_03018 6.2e-125 yesU S Domain of unknown function (DUF1961)
HAGICGNN_03019 1.3e-102 E GDSL-like Lipase/Acylhydrolase
HAGICGNN_03020 3.5e-11 E GDSL-like Lipase/Acylhydrolase
HAGICGNN_03021 0.0 yesS K Transcriptional regulator
HAGICGNN_03022 3.4e-194 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HAGICGNN_03023 6.1e-160 yesQ P Binding-protein-dependent transport system inner membrane component
HAGICGNN_03024 4e-170 yesP G Binding-protein-dependent transport system inner membrane component
HAGICGNN_03025 1.3e-240 yesO G Bacterial extracellular solute-binding protein
HAGICGNN_03026 8e-194 yesN K helix_turn_helix, arabinose operon control protein
HAGICGNN_03027 7.9e-297 yesM 2.7.13.3 T Histidine kinase
HAGICGNN_03028 1.8e-94 yesL S Protein of unknown function, DUF624
HAGICGNN_03030 5.3e-90 yesJ K Acetyltransferase (GNAT) family
HAGICGNN_03031 3.4e-103 cotJC P Spore Coat
HAGICGNN_03032 4.3e-45 cotJB S CotJB protein
HAGICGNN_03033 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HAGICGNN_03034 2.5e-142 yesF GM NAD(P)H-binding
HAGICGNN_03035 2.2e-78 yesE S SnoaL-like domain
HAGICGNN_03036 1.2e-95 dhaR3 K Transcriptional regulator
HAGICGNN_03038 2e-124 yeeN K transcriptional regulatory protein
HAGICGNN_03040 1.1e-177 S Tetratricopeptide repeat
HAGICGNN_03041 3.3e-49
HAGICGNN_03042 9.6e-100 L endonuclease activity
HAGICGNN_03044 0.0 L nucleic acid phosphodiester bond hydrolysis
HAGICGNN_03045 3.6e-50 S Protein of unknown function, DUF600
HAGICGNN_03046 6.3e-52 S Protein of unknown function, DUF600
HAGICGNN_03047 1.3e-83 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HAGICGNN_03048 0.0 2.1.1.72, 3.1.21.4 L DEAD-like helicases superfamily
HAGICGNN_03049 2.4e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HAGICGNN_03050 8.7e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HAGICGNN_03051 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HAGICGNN_03052 4.3e-139 yerO K Transcriptional regulator
HAGICGNN_03053 2.6e-269 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAGICGNN_03054 1.3e-271 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HAGICGNN_03055 2.8e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HAGICGNN_03056 1.3e-260 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAGICGNN_03057 1.5e-121 sapB S MgtC SapB transporter
HAGICGNN_03058 1.2e-183 yerI S homoserine kinase type II (protein kinase fold)
HAGICGNN_03059 3.3e-217 camS S COG4851 Protein involved in sex pheromone biosynthesis
HAGICGNN_03060 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HAGICGNN_03061 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HAGICGNN_03062 8.7e-122 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HAGICGNN_03063 2.2e-290 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HAGICGNN_03064 4.8e-51 yerC S protein conserved in bacteria
HAGICGNN_03065 8e-185 yerB S Protein of unknown function (DUF3048) C-terminal domain
HAGICGNN_03066 0.0 yerA 3.5.4.2 F adenine deaminase
HAGICGNN_03067 5.9e-30 S Protein of unknown function (DUF2892)
HAGICGNN_03068 1.1e-210 yjeH E Amino acid permease
HAGICGNN_03069 4e-69 K helix_turn_helix ASNC type
HAGICGNN_03070 4.4e-228 purD 6.3.4.13 F Belongs to the GARS family
HAGICGNN_03071 6.8e-284 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HAGICGNN_03072 5.5e-101 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HAGICGNN_03073 1.9e-173 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HAGICGNN_03074 2.8e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HAGICGNN_03075 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAGICGNN_03076 2.8e-128 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAGICGNN_03077 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HAGICGNN_03078 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HAGICGNN_03079 1.4e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HAGICGNN_03080 7.7e-208 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HAGICGNN_03081 2.2e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HAGICGNN_03082 1.4e-27 yebG S NETI protein
HAGICGNN_03083 4e-93 yebE S UPF0316 protein
HAGICGNN_03085 4e-110 yebC M Membrane
HAGICGNN_03086 3.3e-210 pbuG S permease
HAGICGNN_03087 1.2e-245 S Domain of unknown function (DUF4179)
HAGICGNN_03088 7.3e-84 K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_03089 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HAGICGNN_03090 0.0 yebA E COG1305 Transglutaminase-like enzymes
HAGICGNN_03091 2.7e-203 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HAGICGNN_03092 8.6e-168 yeaC S COG0714 MoxR-like ATPases
HAGICGNN_03093 1.1e-148 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAGICGNN_03094 1.5e-248 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_03095 2.1e-309 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HAGICGNN_03096 4.7e-153 yeaA S Protein of unknown function (DUF4003)
HAGICGNN_03097 1.9e-147 ydjP I Alpha/beta hydrolase family
HAGICGNN_03098 1.2e-34 ydjO S Cold-inducible protein YdjO
HAGICGNN_03099 4.8e-61 yusQ S Tautomerase enzyme
HAGICGNN_03100 2.6e-111 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_03101 3.7e-149 yusT K LysR substrate binding domain
HAGICGNN_03102 1.4e-37 yusU S Protein of unknown function (DUF2573)
HAGICGNN_03103 2.6e-152 yusV 3.6.3.34 HP ABC transporter
HAGICGNN_03104 1.3e-67 S YusW-like protein
HAGICGNN_03105 2.7e-303 pepF2 E COG1164 Oligoendopeptidase F
HAGICGNN_03106 1.6e-146 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_03107 5.2e-78 dps P Ferritin-like domain
HAGICGNN_03108 5.1e-222 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAGICGNN_03109 3.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_03110 9.4e-245 cssS 2.7.13.3 T PhoQ Sensor
HAGICGNN_03111 1.7e-23
HAGICGNN_03112 8.4e-154 yuxN K Transcriptional regulator
HAGICGNN_03113 1.1e-259 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAGICGNN_03114 3.9e-24 S Protein of unknown function (DUF3970)
HAGICGNN_03115 2e-237 gerAA EG Spore germination protein
HAGICGNN_03116 5.5e-179 gerAB E Spore germination protein
HAGICGNN_03117 1.8e-172 gerAC S Spore germination B3/ GerAC like, C-terminal
HAGICGNN_03118 2.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_03119 7.4e-184 vraS 2.7.13.3 T Histidine kinase
HAGICGNN_03120 2e-121 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HAGICGNN_03121 3e-95 liaG S Putative adhesin
HAGICGNN_03122 1.1e-97 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HAGICGNN_03123 1.6e-61 liaI S membrane
HAGICGNN_03124 5e-224 yvqJ EGP Major facilitator Superfamily
HAGICGNN_03125 9.4e-93 yvqK 2.5.1.17 S Adenosyltransferase
HAGICGNN_03126 2.8e-217 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HAGICGNN_03127 3.8e-177 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03128 2.2e-163 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HAGICGNN_03129 6.5e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_03130 2.7e-160 yvrE G SMP-30/Gluconolaconase/LRE-like region
HAGICGNN_03131 1.3e-307 T PhoQ Sensor
HAGICGNN_03132 1.2e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_03133 5.8e-25
HAGICGNN_03134 1.9e-98 yvrI K RNA polymerase
HAGICGNN_03135 5e-17 S YvrJ protein family
HAGICGNN_03136 3.4e-227 oxdC 4.1.1.2 G Oxalate decarboxylase
HAGICGNN_03137 2.5e-47 yvrL S Regulatory protein YrvL
HAGICGNN_03138 5.2e-194 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HAGICGNN_03139 1.1e-121 macB V ABC transporter, ATP-binding protein
HAGICGNN_03140 1.7e-168 M Efflux transporter rnd family, mfp subunit
HAGICGNN_03141 6.6e-145 fhuC 3.6.3.34 HP ABC transporter
HAGICGNN_03142 1.8e-171 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03143 2e-178 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03144 5e-160 fhuD P ABC transporter
HAGICGNN_03146 4.7e-231 yvsH E Arginine ornithine antiporter
HAGICGNN_03147 1.5e-15 S Small spore protein J (Spore_SspJ)
HAGICGNN_03148 1.5e-83 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HAGICGNN_03149 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HAGICGNN_03150 1e-157 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HAGICGNN_03151 9.9e-130 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HAGICGNN_03152 1.3e-114 modB P COG4149 ABC-type molybdate transport system, permease component
HAGICGNN_03153 3e-153 yvgN S reductase
HAGICGNN_03154 5.1e-84 yvgO
HAGICGNN_03155 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HAGICGNN_03156 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HAGICGNN_03157 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HAGICGNN_03158 0.0 helD 3.6.4.12 L DNA helicase
HAGICGNN_03159 1.3e-105 yvgT S membrane
HAGICGNN_03160 4.2e-71 bdbC O Required for disulfide bond formation in some proteins
HAGICGNN_03161 9.1e-100 bdbD O Thioredoxin
HAGICGNN_03162 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HAGICGNN_03163 0.0 copA 3.6.3.54 P P-type ATPase
HAGICGNN_03164 1e-28 copZ P Copper resistance protein CopZ
HAGICGNN_03165 2e-46 csoR S transcriptional
HAGICGNN_03166 1.6e-180 yvaA 1.1.1.371 S Oxidoreductase
HAGICGNN_03167 6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HAGICGNN_03168 3e-136 exoK GH16 M licheninase activity
HAGICGNN_03169 1.2e-67 yvaD S Family of unknown function (DUF5360)
HAGICGNN_03170 2.3e-49 yvaE P Small Multidrug Resistance protein
HAGICGNN_03171 1.2e-92 K Bacterial regulatory proteins, tetR family
HAGICGNN_03172 3e-126 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_03174 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HAGICGNN_03175 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HAGICGNN_03176 2.1e-142 est 3.1.1.1 S Carboxylesterase
HAGICGNN_03177 2.4e-23 secG U Preprotein translocase subunit SecG
HAGICGNN_03178 6.6e-134 yvaM S Serine aminopeptidase, S33
HAGICGNN_03179 9.8e-36 yvzC K Transcriptional
HAGICGNN_03180 4e-69 K transcriptional
HAGICGNN_03181 6.4e-67 yvaO K Cro/C1-type HTH DNA-binding domain
HAGICGNN_03182 4.8e-54 yodB K transcriptional
HAGICGNN_03183 1e-179 NT chemotaxis protein
HAGICGNN_03184 1.5e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HAGICGNN_03185 1.2e-163 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAGICGNN_03186 1.2e-107 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HAGICGNN_03187 2.5e-206 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HAGICGNN_03188 8.1e-83 yvbF K Belongs to the GbsR family
HAGICGNN_03189 1.2e-104 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HAGICGNN_03190 8.2e-168 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HAGICGNN_03191 1.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HAGICGNN_03192 8.5e-207 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HAGICGNN_03193 1.8e-93 yvbF K Belongs to the GbsR family
HAGICGNN_03194 3.3e-99 yvbG U UPF0056 membrane protein
HAGICGNN_03195 4.4e-109 yvbH S YvbH-like oligomerisation region
HAGICGNN_03196 2.5e-116 exoY M Membrane
HAGICGNN_03197 0.0 tcaA S response to antibiotic
HAGICGNN_03198 2.8e-76 yvbK 3.1.3.25 K acetyltransferase
HAGICGNN_03199 8.2e-171 EGP Major facilitator Superfamily
HAGICGNN_03200 7.5e-153
HAGICGNN_03201 1.7e-114 S GlcNAc-PI de-N-acetylase
HAGICGNN_03202 3.2e-125 C WbqC-like protein family
HAGICGNN_03203 2.9e-113 M Protein involved in cellulose biosynthesis
HAGICGNN_03204 4.2e-159 E UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HAGICGNN_03205 1.5e-148 5.1.3.2 M GDP-mannose 4,6 dehydratase
HAGICGNN_03206 2.1e-161 spsC 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HAGICGNN_03207 5.6e-218 1.1.1.136 M UDP binding domain
HAGICGNN_03208 1.2e-172 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HAGICGNN_03209 6.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HAGICGNN_03210 1.5e-294 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HAGICGNN_03211 1.3e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HAGICGNN_03212 1.1e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HAGICGNN_03213 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HAGICGNN_03214 1.7e-182 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HAGICGNN_03215 1.7e-249 araE EGP Major facilitator Superfamily
HAGICGNN_03216 9e-198 araR K transcriptional
HAGICGNN_03217 2.2e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAGICGNN_03218 1.3e-151 yvbU K Transcriptional regulator
HAGICGNN_03219 5.9e-150 yvbV EG EamA-like transporter family
HAGICGNN_03220 4.2e-221 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_03221 7.8e-183 yvbX S Glycosyl hydrolase
HAGICGNN_03222 3.6e-126 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HAGICGNN_03223 6.2e-271 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HAGICGNN_03224 1.1e-132 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HAGICGNN_03225 9.7e-101 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_03226 9e-177 desK 2.7.13.3 T Histidine kinase
HAGICGNN_03227 3.3e-127 yvfS V COG0842 ABC-type multidrug transport system, permease component
HAGICGNN_03228 7.9e-147 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HAGICGNN_03229 4.1e-147 rsbQ S Alpha/beta hydrolase family
HAGICGNN_03230 2.7e-166 rsbU 3.1.3.3 T response regulator
HAGICGNN_03231 2.8e-230 galA 3.2.1.89 G arabinogalactan
HAGICGNN_03232 0.0 lacA 3.2.1.23 G beta-galactosidase
HAGICGNN_03233 1.5e-147 ganQ P transport
HAGICGNN_03234 8.7e-229 malC P COG1175 ABC-type sugar transport systems, permease components
HAGICGNN_03235 1.5e-223 cycB G COG2182 Maltose-binding periplasmic proteins domains
HAGICGNN_03236 3.3e-178 lacR K Transcriptional regulator
HAGICGNN_03237 1.4e-114 yvfI K COG2186 Transcriptional regulators
HAGICGNN_03238 5e-304 yvfH C L-lactate permease
HAGICGNN_03239 1.5e-231 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HAGICGNN_03240 1e-31 yvfG S YvfG protein
HAGICGNN_03241 1.6e-182 yvfF GM Exopolysaccharide biosynthesis protein
HAGICGNN_03242 2.7e-208 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HAGICGNN_03243 1.2e-40 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HAGICGNN_03244 4.5e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HAGICGNN_03245 5.6e-246 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_03246 7.1e-176 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HAGICGNN_03247 8.6e-193 epsI GM pyruvyl transferase
HAGICGNN_03248 1.2e-186 epsH GT2 S Glycosyltransferase like family 2
HAGICGNN_03249 1.4e-201 epsG S EpsG family
HAGICGNN_03250 1.7e-202 epsF GT4 M Glycosyl transferases group 1
HAGICGNN_03251 6.6e-156 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HAGICGNN_03252 1.7e-202 epsD GT4 M Glycosyl transferase 4-like
HAGICGNN_03253 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HAGICGNN_03254 3.3e-113 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HAGICGNN_03255 7.1e-119 ywqC M biosynthesis protein
HAGICGNN_03256 1e-73 slr K transcriptional
HAGICGNN_03257 5.9e-261 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HAGICGNN_03259 1e-92 padC Q Phenolic acid decarboxylase
HAGICGNN_03260 4e-75 MA20_18690 S Protein of unknown function (DUF3237)
HAGICGNN_03261 7.8e-115 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HAGICGNN_03262 2.9e-230 pbpE V Beta-lactamase
HAGICGNN_03263 3.4e-269 sacB 2.4.1.10 GH68 M levansucrase activity
HAGICGNN_03264 7.1e-297 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HAGICGNN_03265 2.2e-290 yveA E amino acid
HAGICGNN_03266 8e-100 yvdT K Transcriptional regulator
HAGICGNN_03267 6.9e-48 ykkC P Small Multidrug Resistance protein
HAGICGNN_03268 1.5e-47 sugE P Small Multidrug Resistance protein
HAGICGNN_03269 1.5e-89 yvdQ S Protein of unknown function (DUF3231)
HAGICGNN_03271 9.3e-104 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HAGICGNN_03272 3.1e-103 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HAGICGNN_03273 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HAGICGNN_03274 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HAGICGNN_03275 3.7e-133 malA S Protein of unknown function (DUF1189)
HAGICGNN_03276 1.8e-145 malD P transport
HAGICGNN_03277 7.4e-231 malC P COG1175 ABC-type sugar transport systems, permease components
HAGICGNN_03278 2.1e-227 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HAGICGNN_03279 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HAGICGNN_03280 4.5e-169 yvdE K Transcriptional regulator
HAGICGNN_03281 3.1e-104 yvdD 3.2.2.10 S Belongs to the LOG family
HAGICGNN_03282 2.6e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HAGICGNN_03283 3.2e-284 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HAGICGNN_03284 9.4e-101 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HAGICGNN_03285 5.8e-180 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HAGICGNN_03286 0.0 V ABC transporter (permease)
HAGICGNN_03287 4.1e-136 yvcR V ABC transporter, ATP-binding protein
HAGICGNN_03288 2.1e-183 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HAGICGNN_03289 1.7e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_03290 1.4e-30
HAGICGNN_03291 4.3e-130 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HAGICGNN_03292 1.6e-36 crh G Phosphocarrier protein Chr
HAGICGNN_03293 1e-168 whiA K May be required for sporulation
HAGICGNN_03294 2.6e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HAGICGNN_03295 6.3e-165 rapZ S Displays ATPase and GTPase activities
HAGICGNN_03296 2e-88 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HAGICGNN_03297 3.2e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HAGICGNN_03298 1.9e-94 usp CBM50 M protein conserved in bacteria
HAGICGNN_03299 6.9e-270 S COG0457 FOG TPR repeat
HAGICGNN_03300 8.3e-310 msbA2 3.6.3.44 V ABC transporter
HAGICGNN_03302 0.0
HAGICGNN_03303 5.4e-114
HAGICGNN_03304 2.1e-97 Otg1 S Predicted membrane protein (DUF2339)
HAGICGNN_03305 2e-109 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HAGICGNN_03306 1.1e-133 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HAGICGNN_03307 8.2e-126 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HAGICGNN_03308 3.3e-107 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HAGICGNN_03309 4.4e-106 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HAGICGNN_03310 1.7e-219 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HAGICGNN_03311 3.7e-114 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HAGICGNN_03312 5.7e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HAGICGNN_03313 7e-133 yvpB NU protein conserved in bacteria
HAGICGNN_03314 4.3e-118 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HAGICGNN_03315 3.4e-78 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HAGICGNN_03316 2.8e-114 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HAGICGNN_03317 9.3e-159 yvoD P COG0370 Fe2 transport system protein B
HAGICGNN_03318 1e-145 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HAGICGNN_03319 1.1e-167 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HAGICGNN_03320 6.6e-210 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HAGICGNN_03321 3.2e-122 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAGICGNN_03322 1.7e-128 yvoA K transcriptional
HAGICGNN_03323 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HAGICGNN_03324 4.5e-83 yvmB K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_03325 6.3e-159 yvmA EGP Major facilitator Superfamily
HAGICGNN_03330 2e-08
HAGICGNN_03331 2.8e-171 glcP G Major Facilitator Superfamily
HAGICGNN_03332 1.6e-233 dat 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAGICGNN_03333 2.3e-157 suhB 3.1.3.25, 3.1.3.7 G inositol monophosphate 1-phosphatase activity
HAGICGNN_03334 2.8e-172 1.1.1.14, 1.1.1.303, 1.1.1.4 E alcohol dehydrogenase
HAGICGNN_03335 3.1e-246 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HAGICGNN_03336 1.9e-162 ybaS 1.1.1.58 S Na -dependent transporter
HAGICGNN_03337 7e-125 ybbA S Putative esterase
HAGICGNN_03338 6.5e-174 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03339 2.2e-174 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03340 1.2e-150 feuA P Iron-uptake system-binding protein
HAGICGNN_03341 4.7e-280 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HAGICGNN_03342 8.7e-229 ybbC 3.2.1.52 S protein conserved in bacteria
HAGICGNN_03343 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HAGICGNN_03344 2.6e-239 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HAGICGNN_03345 3.1e-227 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_03346 3.6e-141 ybbH K transcriptional
HAGICGNN_03347 1.7e-149 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HAGICGNN_03348 8.5e-79 ybbJ J acetyltransferase
HAGICGNN_03349 5.3e-75 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HAGICGNN_03355 7.2e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_03356 3.4e-96 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HAGICGNN_03357 1e-145 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HAGICGNN_03358 6.6e-220 ybbR S protein conserved in bacteria
HAGICGNN_03359 6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HAGICGNN_03360 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HAGICGNN_03361 1.2e-98 bcrC 3.6.1.27 I Bacitracin ABC transporter permease
HAGICGNN_03362 5.9e-251 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HAGICGNN_03363 0.0 ybcC S Belongs to the UPF0753 family
HAGICGNN_03364 2e-75 can 4.2.1.1 P carbonic anhydrase
HAGICGNN_03365 4.6e-40
HAGICGNN_03366 4.5e-53 ybcI S Uncharacterized conserved protein (DUF2294)
HAGICGNN_03367 1.6e-57 ybzH K Helix-turn-helix domain
HAGICGNN_03368 1.5e-198 ybcL EGP Major facilitator Superfamily
HAGICGNN_03369 1.6e-110 V CAAX protease self-immunity
HAGICGNN_03370 1.1e-79 skfF S ABC transporter
HAGICGNN_03371 1.4e-84 C HEAT repeats
HAGICGNN_03372 1.1e-66 txn CO Thioredoxin-like
HAGICGNN_03373 4.3e-175 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HAGICGNN_03374 3.7e-117 T Transcriptional regulatory protein, C terminal
HAGICGNN_03375 8e-153 T His Kinase A (phospho-acceptor) domain
HAGICGNN_03377 1.2e-127 KLT Protein tyrosine kinase
HAGICGNN_03378 7e-145 ybdN
HAGICGNN_03379 1.1e-182 ybdO S Domain of unknown function (DUF4885)
HAGICGNN_03380 1.9e-253 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_03381 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
HAGICGNN_03382 2.7e-28 ybxH S Family of unknown function (DUF5370)
HAGICGNN_03383 1.9e-31 ybxI 3.5.2.6 V beta-lactamase
HAGICGNN_03384 4.6e-28 ybxI 3.5.2.6 V beta-lactamase
HAGICGNN_03385 3.3e-31 ybxI 3.5.2.6 V beta-lactamase
HAGICGNN_03386 5.7e-228 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HAGICGNN_03387 1e-38 ybyB
HAGICGNN_03388 4.3e-276 nptA P COG1283 Na phosphate symporter
HAGICGNN_03389 8.6e-154 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HAGICGNN_03390 1.8e-256 glpT G -transporter
HAGICGNN_03391 3.5e-28 S Protein of unknown function (DUF2651)
HAGICGNN_03392 2.8e-160 ybfA 3.4.15.5 K FR47-like protein
HAGICGNN_03393 1.5e-212 ybfB G COG0477 Permeases of the major facilitator superfamily
HAGICGNN_03395 0.0 ybfG M Domain of unknown function (DUF1906)
HAGICGNN_03396 1.3e-149 ybfH EG EamA-like transporter family
HAGICGNN_03397 8.5e-140 msmR K AraC-like ligand binding domain
HAGICGNN_03398 5e-150 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HAGICGNN_03399 1.1e-79 M nucleic acid phosphodiester bond hydrolysis
HAGICGNN_03400 1.9e-206 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HAGICGNN_03401 8.4e-168 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HAGICGNN_03403 1.8e-148 S Alpha/beta hydrolase family
HAGICGNN_03404 7.3e-92 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HAGICGNN_03405 3.3e-83 ybfM S SNARE associated Golgi protein
HAGICGNN_03406 1.4e-142 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HAGICGNN_03407 3.4e-40 ybfN
HAGICGNN_03408 3.5e-07 S Erythromycin esterase
HAGICGNN_03409 4.9e-187 yceA S Belongs to the UPF0176 family
HAGICGNN_03410 2e-209 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAGICGNN_03411 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HAGICGNN_03412 1.7e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HAGICGNN_03413 1.3e-126 K UTRA
HAGICGNN_03415 2e-189 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HAGICGNN_03416 6.8e-254 mmuP E amino acid
HAGICGNN_03417 3e-173 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HAGICGNN_03418 4.9e-252 agcS E Sodium alanine symporter
HAGICGNN_03419 2e-175 glsA 3.5.1.2 E Belongs to the glutaminase family
HAGICGNN_03420 1.4e-218 phoQ 2.7.13.3 T Histidine kinase
HAGICGNN_03421 2.5e-159 glnL T Regulator
HAGICGNN_03422 1.1e-167 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HAGICGNN_03423 9.4e-267 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAGICGNN_03424 4.7e-252 gudP G COG0477 Permeases of the major facilitator superfamily
HAGICGNN_03425 3.6e-260 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HAGICGNN_03426 4e-122 ycbG K FCD
HAGICGNN_03427 1.5e-291 garD 4.2.1.42, 4.2.1.7 G Altronate
HAGICGNN_03428 5e-157 ycbJ S Macrolide 2'-phosphotransferase
HAGICGNN_03429 3.7e-23 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HAGICGNN_03430 1.4e-143 eamA1 EG spore germination
HAGICGNN_03431 9.1e-119 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_03432 1.1e-154 T PhoQ Sensor
HAGICGNN_03433 4.7e-163 ycbN V ABC transporter, ATP-binding protein
HAGICGNN_03434 2.1e-107 S ABC-2 family transporter protein
HAGICGNN_03435 1.4e-52 ycbP S Protein of unknown function (DUF2512)
HAGICGNN_03436 1.7e-96 O Belongs to the serpin family
HAGICGNN_03437 1.2e-76 sleB 3.5.1.28 M Cell wall
HAGICGNN_03438 4.6e-129 ycbR T vWA found in TerF C terminus
HAGICGNN_03439 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HAGICGNN_03440 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HAGICGNN_03441 8.6e-120 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HAGICGNN_03442 1.4e-113 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HAGICGNN_03443 7.3e-179 ycbU E Selenocysteine lyase
HAGICGNN_03444 4e-230 lmrB EGP the major facilitator superfamily
HAGICGNN_03445 1.6e-97 yxaF K Transcriptional regulator
HAGICGNN_03446 6.5e-183 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HAGICGNN_03447 9.9e-112 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HAGICGNN_03448 5.5e-57 S RDD family
HAGICGNN_03449 3.9e-193 yccF K DNA-templated transcriptional preinitiation complex assembly
HAGICGNN_03450 8.3e-131 2.7.13.3 T GHKL domain
HAGICGNN_03451 4e-122 lytR_2 T LytTr DNA-binding domain
HAGICGNN_03452 7.2e-130 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HAGICGNN_03453 2.5e-193 natB CP ABC-2 family transporter protein
HAGICGNN_03454 3.9e-165 yccK C Aldo keto reductase
HAGICGNN_03455 3.6e-175 ycdA S Domain of unknown function (DUF5105)
HAGICGNN_03456 1.9e-66 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_03457 6.7e-111 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_03458 7.7e-239 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HAGICGNN_03459 5.8e-91 cwlK M D-alanyl-D-alanine carboxypeptidase
HAGICGNN_03460 7.2e-166 S response regulator aspartate phosphatase
HAGICGNN_03461 1.7e-134 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_03462 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HAGICGNN_03463 7.6e-162 adcA P Belongs to the bacterial solute-binding protein 9 family
HAGICGNN_03464 7.9e-131 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HAGICGNN_03465 3.3e-131 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HAGICGNN_03466 2.3e-176 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HAGICGNN_03467 5.3e-107 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HAGICGNN_03468 2e-103 yceD T proteins involved in stress response, homologs of TerZ and
HAGICGNN_03469 1.5e-106 yceE T proteins involved in stress response, homologs of TerZ and
HAGICGNN_03470 4.5e-135 terC P Protein of unknown function (DUF475)
HAGICGNN_03471 2e-310 yceG S Putative component of 'biosynthetic module'
HAGICGNN_03472 4.8e-191 yceH P Belongs to the TelA family
HAGICGNN_03473 1.2e-214 naiP P Uncharacterised MFS-type transporter YbfB
HAGICGNN_03474 1e-194 yceJ EGP Uncharacterised MFS-type transporter YbfB
HAGICGNN_03475 4.7e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HAGICGNN_03476 6.9e-226 proV 3.6.3.32 E glycine betaine
HAGICGNN_03477 2.2e-127 opuAB P glycine betaine
HAGICGNN_03478 4.6e-160 opuAC E glycine betaine
HAGICGNN_03479 5.6e-214 amhX S amidohydrolase
HAGICGNN_03480 6.9e-254 ycgA S Membrane
HAGICGNN_03481 2.7e-77 ycgB
HAGICGNN_03482 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HAGICGNN_03483 8.9e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HAGICGNN_03484 3.2e-284 lctP C L-lactate permease
HAGICGNN_03485 2.1e-256 mdr EGP Major facilitator Superfamily
HAGICGNN_03486 1.2e-74 emrR K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_03487 3.7e-111 ycgF E Lysine exporter protein LysE YggA
HAGICGNN_03488 1.5e-143 yqcI S YqcI/YcgG family
HAGICGNN_03489 2.8e-241 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_03490 1e-110 ycgI S Domain of unknown function (DUF1989)
HAGICGNN_03491 5.5e-147 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HAGICGNN_03492 7.6e-98 tmrB S AAA domain
HAGICGNN_03493 1.5e-100 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HAGICGNN_03494 2.7e-132 yafE Q ubiE/COQ5 methyltransferase family
HAGICGNN_03495 1.4e-165 oxyR3 K LysR substrate binding domain
HAGICGNN_03496 3.7e-179 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HAGICGNN_03497 4.7e-140 ycgL S Predicted nucleotidyltransferase
HAGICGNN_03498 2.9e-165 ycgM E Proline dehydrogenase
HAGICGNN_03499 1.5e-291 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HAGICGNN_03500 5.1e-257 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HAGICGNN_03501 3.4e-225 ycgP QT COG2508 Regulator of polyketide synthase expression
HAGICGNN_03502 8.5e-143 ycgQ S membrane
HAGICGNN_03503 1.9e-140 ycgR S permeases
HAGICGNN_03504 1.2e-144 I alpha/beta hydrolase fold
HAGICGNN_03505 3.3e-186 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HAGICGNN_03506 9e-262 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HAGICGNN_03507 1.1e-55 nirD 1.7.1.15 P Nitrite reductase
HAGICGNN_03508 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HAGICGNN_03509 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HAGICGNN_03510 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HAGICGNN_03511 3.3e-217 nasA P COG2223 Nitrate nitrite transporter
HAGICGNN_03512 1.3e-157 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HAGICGNN_03513 5e-84 yciB M ErfK YbiS YcfS YnhG
HAGICGNN_03515 8.3e-221 yciC S GTPases (G3E family)
HAGICGNN_03516 7.8e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
HAGICGNN_03517 1.6e-125 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HAGICGNN_03518 1.4e-201 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HAGICGNN_03519 1.6e-68 yckC S membrane
HAGICGNN_03520 4.9e-46 yckD S Protein of unknown function (DUF2680)
HAGICGNN_03521 1.9e-39 K MarR family
HAGICGNN_03522 2.1e-23
HAGICGNN_03523 3e-120 S AAA domain
HAGICGNN_03524 9.2e-291 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HAGICGNN_03525 7.2e-68 nin S Competence protein J (ComJ)
HAGICGNN_03526 3e-67 nucA M Deoxyribonuclease NucA/NucB
HAGICGNN_03527 8.5e-150 tlpC 2.7.13.3 NT chemotaxis protein
HAGICGNN_03528 6e-89 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HAGICGNN_03529 1.4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HAGICGNN_03530 5.3e-62 hxlR K transcriptional
HAGICGNN_03531 8.9e-265 dtpT E amino acid peptide transporter
HAGICGNN_03532 1e-288 yclG M Pectate lyase superfamily protein
HAGICGNN_03534 1.3e-264 gerKA EG Spore germination protein
HAGICGNN_03535 3.5e-206 gerKC S spore germination
HAGICGNN_03536 1.4e-190 gerKB F Spore germination protein
HAGICGNN_03537 1.7e-117 yclH P ABC transporter
HAGICGNN_03538 1.7e-199 yclI V ABC transporter (permease) YclI
HAGICGNN_03539 2.6e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HAGICGNN_03540 2.7e-247 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HAGICGNN_03541 3.9e-74 S aspartate phosphatase
HAGICGNN_03545 2.5e-245 lysC 2.7.2.4 E Belongs to the aspartokinase family
HAGICGNN_03546 1.7e-160 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03547 1.4e-162 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HAGICGNN_03548 1.7e-134 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HAGICGNN_03549 1.2e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HAGICGNN_03550 2.1e-247 ycnB EGP Major facilitator Superfamily
HAGICGNN_03551 1.6e-149 ycnC K Transcriptional regulator
HAGICGNN_03552 1.1e-130 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HAGICGNN_03553 6.1e-45 ycnE S Monooxygenase
HAGICGNN_03554 3.7e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HAGICGNN_03555 5.6e-256 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_03556 1.2e-241 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HAGICGNN_03557 2.3e-262 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HAGICGNN_03558 5.4e-145 glcU U Glucose uptake
HAGICGNN_03559 3.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_03560 1.3e-92 ycnI S protein conserved in bacteria
HAGICGNN_03561 1.9e-292 ycnJ P protein, homolog of Cu resistance protein CopC
HAGICGNN_03562 1.7e-102 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HAGICGNN_03563 4.1e-51
HAGICGNN_03564 3.2e-235 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HAGICGNN_03565 2.2e-70 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HAGICGNN_03566 1.5e-200 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HAGICGNN_03567 9.7e-197 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HAGICGNN_03568 2.7e-89 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HAGICGNN_03569 1.2e-90 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HAGICGNN_03570 5.1e-66 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HAGICGNN_03572 7.5e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HAGICGNN_03573 1.1e-133 ycsF S Belongs to the UPF0271 (lamB) family
HAGICGNN_03574 9.7e-209 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HAGICGNN_03575 7.1e-136 ycsI S Belongs to the D-glutamate cyclase family
HAGICGNN_03576 1e-128 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HAGICGNN_03577 3.1e-176 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HAGICGNN_03578 3.4e-127 kipR K Transcriptional regulator
HAGICGNN_03579 1.5e-112 ycsK E anatomical structure formation involved in morphogenesis
HAGICGNN_03581 3.5e-48 yczJ S biosynthesis
HAGICGNN_03582 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HAGICGNN_03583 4e-167 ydhF S Oxidoreductase
HAGICGNN_03584 0.0 mtlR K transcriptional regulator, MtlR
HAGICGNN_03585 1e-279 ydaB IQ acyl-CoA ligase
HAGICGNN_03586 3.1e-91 ydaC Q Methyltransferase domain
HAGICGNN_03587 2.2e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_03588 5.1e-95 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HAGICGNN_03589 7.3e-95 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HAGICGNN_03590 2e-76 ydaG 1.4.3.5 S general stress protein
HAGICGNN_03591 1.5e-136 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HAGICGNN_03592 1.4e-44 ydzA EGP Major facilitator Superfamily
HAGICGNN_03593 1.4e-46
HAGICGNN_03594 2.3e-22 XK27_00085 K transcriptional
HAGICGNN_03595 1.2e-73 lrpC K Transcriptional regulator
HAGICGNN_03596 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HAGICGNN_03597 9.3e-195 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HAGICGNN_03598 3.1e-145 ydaK T Diguanylate cyclase, GGDEF domain
HAGICGNN_03599 1.7e-307 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HAGICGNN_03600 2.5e-231 ydaM M Glycosyl transferase family group 2
HAGICGNN_03601 0.0 ydaN S Bacterial cellulose synthase subunit
HAGICGNN_03602 0.0 ydaO E amino acid
HAGICGNN_03603 2.5e-61 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HAGICGNN_03604 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HAGICGNN_03606 3e-38
HAGICGNN_03607 3.6e-222 mntH P H( )-stimulated, divalent metal cation uptake system
HAGICGNN_03608 1.8e-16 ydaS S membrane
HAGICGNN_03609 2.1e-68 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HAGICGNN_03610 3.8e-140 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HAGICGNN_03612 3e-54 ydbB G Cupin domain
HAGICGNN_03613 7.4e-48 ydbC S Domain of unknown function (DUF4937
HAGICGNN_03614 1.3e-151 ydbD P Catalase
HAGICGNN_03615 4.1e-187 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HAGICGNN_03616 1.5e-289 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HAGICGNN_03617 3.9e-114 dctR T COG4565 Response regulator of citrate malate metabolism
HAGICGNN_03619 8.2e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAGICGNN_03620 3.3e-173 ydbI S AI-2E family transporter
HAGICGNN_03621 4.3e-204 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HAGICGNN_03622 6.1e-163 ydbJ V ABC transporter, ATP-binding protein
HAGICGNN_03623 1.8e-120 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HAGICGNN_03624 4.6e-52 ydbL
HAGICGNN_03625 5.9e-208 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HAGICGNN_03626 1.1e-18 S Fur-regulated basic protein B
HAGICGNN_03628 8.4e-146 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAGICGNN_03629 1.5e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HAGICGNN_03630 1.8e-198 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HAGICGNN_03631 2.5e-245 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HAGICGNN_03632 1.5e-243 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HAGICGNN_03633 1e-81 ydbS S Bacterial PH domain
HAGICGNN_03634 2.7e-245 ydbT S Membrane
HAGICGNN_03635 4.2e-104 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HAGICGNN_03636 5.8e-56 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HAGICGNN_03637 3.5e-180 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HAGICGNN_03638 3.8e-210 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HAGICGNN_03639 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HAGICGNN_03640 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HAGICGNN_03641 1.3e-140 rsbR T Positive regulator of sigma-B
HAGICGNN_03642 6.8e-57 rsbS T antagonist
HAGICGNN_03643 1.5e-68 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HAGICGNN_03644 4.8e-185 rsbU 3.1.3.3 KT phosphatase
HAGICGNN_03645 2.3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
HAGICGNN_03646 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HAGICGNN_03647 2.2e-137 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HAGICGNN_03648 6.9e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HAGICGNN_03649 8.9e-16 S Polyketide cyclase / dehydrase and lipid transport
HAGICGNN_03650 1e-56 ydcG S EVE domain
HAGICGNN_03651 4.2e-69 ydcH K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_03652 0.0 yhgF K COG2183 Transcriptional accessory protein
HAGICGNN_03653 1.7e-81 ydcK S Belongs to the SprT family
HAGICGNN_03661 8.9e-193 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HAGICGNN_03662 3e-30 cspL K Cold shock
HAGICGNN_03663 3.5e-74 carD K Transcription factor
HAGICGNN_03664 1.4e-75 bkdR K helix_turn_helix ASNC type
HAGICGNN_03665 4.4e-127 azlC E AzlC protein
HAGICGNN_03666 2.6e-47 azlD E Branched-chain amino acid transport protein (AzlD)
HAGICGNN_03667 5.4e-12 paaI Q Thioesterase superfamily
HAGICGNN_03668 4.2e-213 brnQ E Component of the transport system for branched-chain amino acids
HAGICGNN_03669 4.2e-19 rok K Repressor of ComK
HAGICGNN_03670 3.6e-149 ydeE K AraC family transcriptional regulator
HAGICGNN_03671 1.2e-247 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_03672 1.6e-196 ydeG EGP Major facilitator superfamily
HAGICGNN_03673 5.1e-47 ydeH
HAGICGNN_03674 5.6e-93 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HAGICGNN_03676 2.9e-60 ykvN K Transcriptional regulator
HAGICGNN_03677 5.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HAGICGNN_03678 4e-58
HAGICGNN_03679 1.7e-154 K Transcriptional regulator
HAGICGNN_03680 3.3e-253 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HAGICGNN_03681 2.9e-134 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HAGICGNN_03682 1.6e-67 lrpA K transcriptional
HAGICGNN_03683 0.0 M Domain of unknown function DUF11
HAGICGNN_03684 5.1e-78 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HAGICGNN_03685 5.2e-148 ydeK EG -transporter
HAGICGNN_03686 2.3e-254 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_03687 1.2e-68 maoC I N-terminal half of MaoC dehydratase
HAGICGNN_03688 2.6e-147 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HAGICGNN_03689 7.4e-177 ydeR EGP Major facilitator Superfamily
HAGICGNN_03690 3e-99 ydeS K Transcriptional regulator
HAGICGNN_03691 5e-54 arsR K transcriptional
HAGICGNN_03692 4.6e-217 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HAGICGNN_03693 6.6e-72 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HAGICGNN_03694 2.2e-113 ydfB J GNAT acetyltransferase
HAGICGNN_03695 6.1e-147 ydfC EG EamA-like transporter family
HAGICGNN_03696 3.2e-259 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HAGICGNN_03697 1e-108 ydfE S Flavin reductase like domain
HAGICGNN_03698 2.9e-109 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HAGICGNN_03699 3.5e-71 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAGICGNN_03701 2.9e-168 ydfH 2.7.13.3 T Histidine kinase
HAGICGNN_03702 1.5e-107 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_03703 0.0 ydfJ S drug exporters of the RND superfamily
HAGICGNN_03704 5.2e-95 3.1.3.18, 3.2.2.9 F haloacid dehalogenase-like hydrolase
HAGICGNN_03705 5.9e-73 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HAGICGNN_03706 2.2e-109 S Protein of unknown function (DUF554)
HAGICGNN_03707 5.7e-134 K Bacterial transcription activator, effector binding domain
HAGICGNN_03708 6.1e-152 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HAGICGNN_03709 1.2e-109 ydfN C nitroreductase
HAGICGNN_03710 1.6e-179 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HAGICGNN_03711 9.8e-62 mhqP S DoxX
HAGICGNN_03712 1.5e-53 traF CO Thioredoxin
HAGICGNN_03713 4.1e-203 K helix_turn_helix gluconate operon transcriptional repressor
HAGICGNN_03714 6.2e-82 paiB K Transcriptional regulator
HAGICGNN_03716 2.1e-14 ydgA S Spore germination protein gerPA/gerPF
HAGICGNN_03717 1.1e-28
HAGICGNN_03719 5.2e-31 ydfR S Protein of unknown function (DUF421)
HAGICGNN_03720 8e-66 ydfS S Protein of unknown function (DUF421)
HAGICGNN_03721 2.3e-11 ydfS S Protein of unknown function (DUF421)
HAGICGNN_03722 1.6e-65 cotP O Belongs to the small heat shock protein (HSP20) family
HAGICGNN_03723 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
HAGICGNN_03724 2.1e-34 ydgB S Spore germination protein gerPA/gerPF
HAGICGNN_03725 3.6e-87 K Bacterial regulatory proteins, tetR family
HAGICGNN_03726 4.8e-44 S DoxX-like family
HAGICGNN_03727 2.7e-74 yycN 2.3.1.128 K Acetyltransferase
HAGICGNN_03728 1.7e-285 expZ S ABC transporter
HAGICGNN_03729 1.1e-245 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HAGICGNN_03730 1.1e-79 dinB S DinB family
HAGICGNN_03731 5.4e-75 K helix_turn_helix multiple antibiotic resistance protein
HAGICGNN_03732 0.0 ydgH S drug exporters of the RND superfamily
HAGICGNN_03733 4e-113 drgA C nitroreductase
HAGICGNN_03734 9.2e-69 ydgJ K Winged helix DNA-binding domain
HAGICGNN_03735 9.6e-21 azlD S Branched-chain amino acid transport protein (AzlD)
HAGICGNN_03736 1e-205 tcaB EGP Major facilitator Superfamily
HAGICGNN_03737 1.3e-118 ydhB S membrane transporter protein
HAGICGNN_03738 1.8e-116 ydhC K FCD
HAGICGNN_03739 1e-229 ydhD M Glycosyl hydrolase
HAGICGNN_03740 3.3e-217 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HAGICGNN_03741 3e-109
HAGICGNN_03742 1.4e-251 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HAGICGNN_03743 5.3e-57 frataxin S Domain of unknown function (DU1801)
HAGICGNN_03745 8.6e-68 K Acetyltransferase (GNAT) domain
HAGICGNN_03746 5.5e-162 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HAGICGNN_03747 1.1e-93 ydhK M Protein of unknown function (DUF1541)
HAGICGNN_03748 1.1e-196 pbuE EGP Major facilitator Superfamily
HAGICGNN_03749 1.8e-45 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HAGICGNN_03750 9e-48 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HAGICGNN_03751 1.3e-227 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HAGICGNN_03752 3e-270 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HAGICGNN_03753 4.5e-129 ydhQ K UTRA
HAGICGNN_03754 4e-159 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HAGICGNN_03755 8.5e-176 manA 5.3.1.8 G mannose-6-phosphate isomerase
HAGICGNN_03756 1.2e-197 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HAGICGNN_03757 1e-156 ydhU P Catalase
HAGICGNN_03760 8.5e-86 thiT S Thiamine transporter protein (Thia_YuaJ)
HAGICGNN_03761 8.4e-85 M1-753 M FR47-like protein
HAGICGNN_03762 1e-183 yuaG 3.4.21.72 S protein conserved in bacteria
HAGICGNN_03763 1.7e-69 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HAGICGNN_03764 7.2e-78 yuaE S DinB superfamily
HAGICGNN_03765 1.8e-96 yuaD
HAGICGNN_03766 4.6e-227 gbsB 1.1.1.1 C alcohol dehydrogenase
HAGICGNN_03767 5e-276 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HAGICGNN_03768 3.1e-90 yuaC K Belongs to the GbsR family
HAGICGNN_03769 5.3e-90 yuaB
HAGICGNN_03770 1.1e-118 ktrA P COG0569 K transport systems, NAD-binding component
HAGICGNN_03771 2.9e-230 ktrB P Potassium
HAGICGNN_03772 1.3e-38 yiaA S yiaA/B two helix domain
HAGICGNN_03773 5.7e-147 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAGICGNN_03774 9.7e-243 yubD P Major Facilitator Superfamily
HAGICGNN_03775 1.3e-82 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HAGICGNN_03777 5.2e-129 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HAGICGNN_03778 5.1e-191 yubA S transporter activity
HAGICGNN_03779 2.7e-172 ygjR S Oxidoreductase
HAGICGNN_03780 2.9e-240 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HAGICGNN_03781 2.5e-52 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HAGICGNN_03782 1.7e-247 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HAGICGNN_03783 4.6e-127 fucR K COG1349 Transcriptional regulators of sugar metabolism
HAGICGNN_03784 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HAGICGNN_03785 2.9e-218 mcpA NT chemotaxis protein
HAGICGNN_03786 3.3e-283 mcpA NT chemotaxis protein
HAGICGNN_03787 1.5e-206 mcpA NT chemotaxis protein
HAGICGNN_03788 4e-212 mcpA NT chemotaxis protein
HAGICGNN_03789 1.9e-130 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HAGICGNN_03790 8e-36
HAGICGNN_03791 3.5e-70 yugU S Uncharacterised protein family UPF0047
HAGICGNN_03792 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HAGICGNN_03793 3e-232 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HAGICGNN_03794 9.2e-116 yugP S Zn-dependent protease
HAGICGNN_03795 4.8e-36
HAGICGNN_03796 1.2e-40 mstX S Membrane-integrating protein Mistic
HAGICGNN_03797 4.7e-169 yugO P COG1226 Kef-type K transport systems
HAGICGNN_03798 1.6e-70 yugN S YugN-like family
HAGICGNN_03800 1.3e-259 pgi 5.3.1.9 G Belongs to the GPI family
HAGICGNN_03801 6e-224 yugK C Dehydrogenase
HAGICGNN_03802 6.4e-226 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HAGICGNN_03803 1.1e-34 yuzA S Domain of unknown function (DUF378)
HAGICGNN_03804 4.4e-62 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HAGICGNN_03805 4.8e-213 yugH 2.6.1.1 E Aminotransferase
HAGICGNN_03806 4.7e-85 alaR K Transcriptional regulator
HAGICGNN_03807 1.2e-149 yugF I Hydrolase
HAGICGNN_03808 4.3e-37 yugE S Domain of unknown function (DUF1871)
HAGICGNN_03809 1.2e-219 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HAGICGNN_03810 4e-221 T PhoQ Sensor
HAGICGNN_03811 2.2e-66 kapB G Kinase associated protein B
HAGICGNN_03812 2.5e-112 kapD L the KinA pathway to sporulation
HAGICGNN_03814 2.4e-179 yuxJ EGP Major facilitator Superfamily
HAGICGNN_03815 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HAGICGNN_03816 2.6e-73 yuxK S protein conserved in bacteria
HAGICGNN_03817 2e-76 yufK S Family of unknown function (DUF5366)
HAGICGNN_03818 2.4e-287 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HAGICGNN_03819 1.4e-122 dcuR T COG4565 Response regulator of citrate malate metabolism
HAGICGNN_03820 1.7e-185 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HAGICGNN_03821 1.2e-259 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HAGICGNN_03822 1.8e-179 yufP S Belongs to the binding-protein-dependent transport system permease family
HAGICGNN_03823 5.2e-165 yufQ S Belongs to the binding-protein-dependent transport system permease family
HAGICGNN_03824 1.8e-227 maeN C COG3493 Na citrate symporter
HAGICGNN_03825 8.5e-15
HAGICGNN_03826 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HAGICGNN_03827 7.7e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAGICGNN_03828 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAGICGNN_03829 1.4e-257 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAGICGNN_03830 2.7e-74 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAGICGNN_03831 6.1e-37 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HAGICGNN_03832 2e-56 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HAGICGNN_03833 4.3e-62 ydiI Q protein, possibly involved in aromatic compounds catabolism
HAGICGNN_03834 1.1e-115 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_03835 0.0 comP 2.7.13.3 T Histidine kinase
HAGICGNN_03837 3.7e-147 comQ H Belongs to the FPP GGPP synthase family
HAGICGNN_03839 7.7e-24 yuzC
HAGICGNN_03840 2.6e-225 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HAGICGNN_03841 8.3e-279 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HAGICGNN_03842 2.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HAGICGNN_03843 1.8e-58 yueI S Protein of unknown function (DUF1694)
HAGICGNN_03844 7.2e-34 yueH S YueH-like protein
HAGICGNN_03845 9.6e-30 yueG S Spore germination protein gerPA/gerPF
HAGICGNN_03846 2.1e-186 yueF S transporter activity
HAGICGNN_03847 2.9e-24 S Protein of unknown function (DUF2642)
HAGICGNN_03848 7e-95 yueE S phosphohydrolase
HAGICGNN_03849 1.3e-123 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HAGICGNN_03850 1.7e-60 yueC S Family of unknown function (DUF5383)
HAGICGNN_03851 0.0 esaA S type VII secretion protein EsaA
HAGICGNN_03852 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HAGICGNN_03853 1e-190 essB S WXG100 protein secretion system (Wss), protein YukC
HAGICGNN_03854 1.8e-39 yukD S WXG100 protein secretion system (Wss), protein YukD
HAGICGNN_03855 2.8e-45 esxA S Belongs to the WXG100 family
HAGICGNN_03856 1.6e-219 yukF QT Transcriptional regulator
HAGICGNN_03857 2.8e-202 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HAGICGNN_03858 6.8e-127 yukJ S Uncharacterized conserved protein (DUF2278)
HAGICGNN_03859 6.5e-36 mbtH S MbtH-like protein
HAGICGNN_03860 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HAGICGNN_03861 9.9e-169 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HAGICGNN_03862 1e-301 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HAGICGNN_03863 4.4e-206 entC 5.4.4.2 HQ Isochorismate synthase
HAGICGNN_03864 2.8e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HAGICGNN_03865 3.5e-152 besA S Putative esterase
HAGICGNN_03866 3.3e-117 yuiH S Oxidoreductase molybdopterin binding domain
HAGICGNN_03867 1.6e-87 bioY S Biotin biosynthesis protein
HAGICGNN_03868 4.3e-194 yuiF S antiporter
HAGICGNN_03869 3e-268 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HAGICGNN_03870 2.5e-75 yuiD S protein conserved in bacteria
HAGICGNN_03871 2.4e-113 yuiC S protein conserved in bacteria
HAGICGNN_03872 4.6e-25 yuiB S Putative membrane protein
HAGICGNN_03873 1.1e-233 yumB 1.6.99.3 C NADH dehydrogenase
HAGICGNN_03874 2.3e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
HAGICGNN_03876 6.3e-182 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HAGICGNN_03877 1.2e-78 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HAGICGNN_03878 5.3e-62 erpA S Belongs to the HesB IscA family
HAGICGNN_03879 3.2e-158 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HAGICGNN_03880 9.4e-196 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HAGICGNN_03881 3.2e-39 yuzB S Belongs to the UPF0349 family
HAGICGNN_03882 1.9e-197 yutJ 1.6.99.3 C NADH dehydrogenase
HAGICGNN_03883 5.3e-53 yuzD S protein conserved in bacteria
HAGICGNN_03884 1.6e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HAGICGNN_03885 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HAGICGNN_03886 3.1e-170 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HAGICGNN_03887 1.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HAGICGNN_03888 1.6e-238 hom 1.1.1.3 E homoserine dehydrogenase
HAGICGNN_03889 4.5e-191 yutH S Spore coat protein
HAGICGNN_03890 2.3e-75 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HAGICGNN_03891 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HAGICGNN_03892 1.2e-68 yutE S Protein of unknown function DUF86
HAGICGNN_03893 9.7e-48 yutD S protein conserved in bacteria
HAGICGNN_03894 7.5e-104 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HAGICGNN_03895 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HAGICGNN_03896 5.1e-192 lytH M Peptidase, M23
HAGICGNN_03897 1.7e-129 yunB S Sporulation protein YunB (Spo_YunB)
HAGICGNN_03898 1.7e-48 yunC S Domain of unknown function (DUF1805)
HAGICGNN_03899 4.6e-255 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HAGICGNN_03900 1.5e-136 yunE S membrane transporter protein
HAGICGNN_03901 5.7e-171 yunF S Protein of unknown function DUF72
HAGICGNN_03902 1e-54 yunG
HAGICGNN_03903 2.4e-101 2.4.1.173 GT1 CG UDP-glucoronosyl and UDP-glucosyl transferase
HAGICGNN_03904 1.5e-242 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HAGICGNN_03905 6.4e-293 pucR QT COG2508 Regulator of polyketide synthase expression
HAGICGNN_03906 1.3e-217 pbuX F Permease family
HAGICGNN_03907 2.6e-212 pbuX F xanthine
HAGICGNN_03908 1.9e-254 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HAGICGNN_03909 2.7e-50 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HAGICGNN_03910 1.2e-83 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HAGICGNN_03911 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HAGICGNN_03912 4.3e-131 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HAGICGNN_03913 3e-94 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HAGICGNN_03914 1.1e-165 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HAGICGNN_03916 3.4e-225 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HAGICGNN_03917 1.5e-220 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HAGICGNN_03918 1.4e-158 bsn L Ribonuclease
HAGICGNN_03919 4.3e-195 msmX P Belongs to the ABC transporter superfamily
HAGICGNN_03920 5.2e-133 yurK K UTRA
HAGICGNN_03921 3.7e-154 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HAGICGNN_03922 2.2e-165 yurM P COG0395 ABC-type sugar transport system, permease component
HAGICGNN_03923 4.5e-155 yurN G Binding-protein-dependent transport system inner membrane component
HAGICGNN_03924 3.8e-232 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HAGICGNN_03925 7.7e-180 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HAGICGNN_03926 1.9e-62 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HAGICGNN_03927 7.3e-195 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HAGICGNN_03929 1.7e-36
HAGICGNN_03930 4.6e-271 sufB O FeS cluster assembly
HAGICGNN_03931 3.2e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HAGICGNN_03932 4.3e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HAGICGNN_03933 3.8e-243 sufD O assembly protein SufD
HAGICGNN_03934 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HAGICGNN_03935 4.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HAGICGNN_03936 3.3e-144 metQ P Belongs to the NlpA lipoprotein family
HAGICGNN_03937 8.8e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HAGICGNN_03938 1.5e-181 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HAGICGNN_03939 2.3e-54 yusD S SCP-2 sterol transfer family
HAGICGNN_03940 2e-52 traF CO Thioredoxin
HAGICGNN_03941 2.6e-71 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HAGICGNN_03942 3e-37 yusG S Protein of unknown function (DUF2553)
HAGICGNN_03943 1.2e-64 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HAGICGNN_03944 1.4e-62 arsC 1.20.4.1 P Belongs to the ArsC family
HAGICGNN_03945 8.4e-302 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HAGICGNN_03946 9.7e-214 fadA 2.3.1.16 I Belongs to the thiolase family
HAGICGNN_03947 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HAGICGNN_03948 8.1e-09 S YuzL-like protein
HAGICGNN_03949 1.4e-159 fadM E Proline dehydrogenase
HAGICGNN_03950 5.1e-40
HAGICGNN_03951 9.3e-53 yusN M Coat F domain
HAGICGNN_03952 1.2e-69 yusO K Iron dependent repressor, N-terminal DNA binding domain
HAGICGNN_03953 6.7e-282 yusP P Major facilitator superfamily
HAGICGNN_03954 3.3e-102 S response regulator aspartate phosphatase
HAGICGNN_03955 3.8e-84 ywmF S Peptidase M50
HAGICGNN_03956 5.1e-08 csbD K CsbD-like
HAGICGNN_03957 7.7e-217 urtA E Receptor family ligand binding region
HAGICGNN_03958 5.6e-145 urtB E Belongs to the binding-protein-dependent transport system permease family
HAGICGNN_03959 1.2e-183 urtC E Belongs to the binding-protein-dependent transport system permease family
HAGICGNN_03960 6.3e-118 urtD S ATPases associated with a variety of cellular activities
HAGICGNN_03961 8e-115 urtE E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
HAGICGNN_03962 1.1e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HAGICGNN_03963 1.1e-59 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HAGICGNN_03964 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HAGICGNN_03965 1.6e-62 ywnA K Transcriptional regulator
HAGICGNN_03966 1.9e-107 ywnB S NAD(P)H-binding
HAGICGNN_03967 6.1e-56 ywnC S Family of unknown function (DUF5362)
HAGICGNN_03968 6.8e-131 mta K transcriptional
HAGICGNN_03969 7.8e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HAGICGNN_03970 3.5e-68 ywnF S Family of unknown function (DUF5392)
HAGICGNN_03971 5.5e-192 spsF 2.5.1.56, 2.7.7.92 M NeuB family
HAGICGNN_03972 2.1e-11 ywnC S Family of unknown function (DUF5362)
HAGICGNN_03973 4.3e-86 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HAGICGNN_03974 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HAGICGNN_03975 7.9e-65 ywnJ S VanZ like family
HAGICGNN_03976 2.5e-98 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HAGICGNN_03977 1.6e-58 nrgB K Belongs to the P(II) protein family
HAGICGNN_03978 7.7e-222 amt P Ammonium transporter
HAGICGNN_03979 1.9e-72
HAGICGNN_03980 6.3e-102 phzA Q Isochorismatase family
HAGICGNN_03981 1.1e-226 ywoD EGP Major facilitator superfamily
HAGICGNN_03982 6.8e-273 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HAGICGNN_03983 1e-214 ywoF P Right handed beta helix region
HAGICGNN_03984 2.1e-197 ywoG EGP Major facilitator Superfamily
HAGICGNN_03985 5.1e-69 ywoH K COG1846 Transcriptional regulators
HAGICGNN_03986 3e-44 spoIIID K Stage III sporulation protein D
HAGICGNN_03987 3.5e-180 mbl D Rod shape-determining protein
HAGICGNN_03988 1.5e-117 flhO N flagellar basal body
HAGICGNN_03989 1.4e-139 flhP N flagellar basal body
HAGICGNN_03990 8.3e-188 S aspartate phosphatase
HAGICGNN_03991 1.9e-74 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HAGICGNN_03992 4.4e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HAGICGNN_03993 0.0 ywpD T PhoQ Sensor
HAGICGNN_03994 6.3e-167 M1-574 T Transcriptional regulatory protein, C terminal
HAGICGNN_03995 0.0 M1-568 M cell wall anchor domain
HAGICGNN_03996 3.2e-86 srtA 3.4.22.70 M Sortase family
HAGICGNN_03997 1.7e-64 ywpF S YwpF-like protein
HAGICGNN_03998 3e-63 ywpG
HAGICGNN_03999 1.4e-56 ssbB L Single-stranded DNA-binding protein
HAGICGNN_04000 6.6e-134 glcR K COG1349 Transcriptional regulators of sugar metabolism
HAGICGNN_04001 3.5e-144 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HAGICGNN_04002 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HAGICGNN_04003 6.4e-301 ywqB S SWIM zinc finger
HAGICGNN_04004 6e-17
HAGICGNN_04005 5.7e-111 ywqC M biosynthesis protein
HAGICGNN_04006 1.9e-108 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HAGICGNN_04007 4.5e-127 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HAGICGNN_04008 3.7e-238 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAGICGNN_04009 3.3e-149 ywqG S Domain of unknown function (DUF1963)
HAGICGNN_04010 2.6e-23 S Domain of unknown function (DUF5082)
HAGICGNN_04011 3.9e-38 ywqI S Family of unknown function (DUF5344)
HAGICGNN_04012 0.0 ywqJ S Pre-toxin TG
HAGICGNN_04015 6.1e-61
HAGICGNN_04016 2e-124 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HAGICGNN_04017 3.8e-88 ywrA P COG2059 Chromate transport protein ChrA
HAGICGNN_04018 7.1e-104 ywrB P Chromate transporter
HAGICGNN_04019 4e-81 ywrC K Transcriptional regulator
HAGICGNN_04020 2.2e-290 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HAGICGNN_04021 4.1e-27 S Domain of unknown function (DUF4181)
HAGICGNN_04022 1.1e-104 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HAGICGNN_04023 3.8e-12
HAGICGNN_04024 6.7e-201 cotH M Spore Coat
HAGICGNN_04025 8.8e-143 alsR K LysR substrate binding domain
HAGICGNN_04026 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HAGICGNN_04027 2.2e-142 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HAGICGNN_04028 1e-90 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HAGICGNN_04029 9.2e-44 ywsA S Protein of unknown function (DUF3892)
HAGICGNN_04030 5.6e-84 batE T Sh3 type 3 domain protein
HAGICGNN_04031 6.5e-157 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HAGICGNN_04032 8.1e-150 rbsC G Belongs to the binding-protein-dependent transport system permease family
HAGICGNN_04033 1.1e-265 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HAGICGNN_04034 4.2e-60 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HAGICGNN_04035 8.5e-154 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HAGICGNN_04036 3.7e-166 rbsR K transcriptional
HAGICGNN_04037 6.7e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HAGICGNN_04038 8.6e-70 pgsC S biosynthesis protein
HAGICGNN_04039 1.7e-215 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HAGICGNN_04040 5.8e-19 ywtC
HAGICGNN_04041 1.5e-228 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HAGICGNN_04042 6.1e-157 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HAGICGNN_04043 8.3e-142 ywtF K Transcriptional regulator
HAGICGNN_04044 5.6e-245 ywtG EGP Major facilitator Superfamily
HAGICGNN_04045 1.8e-193 gerAC S Spore germination protein
HAGICGNN_04046 8.6e-188 gerBB E Spore germination protein
HAGICGNN_04047 2.2e-252 gerBA EG Spore germination protein
HAGICGNN_04048 4.6e-182 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HAGICGNN_04049 4e-199 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HAGICGNN_04050 1.7e-191 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAGICGNN_04051 2.7e-91 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAGICGNN_04052 2.1e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HAGICGNN_04053 4.5e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HAGICGNN_04054 9.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HAGICGNN_04055 6e-87 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HAGICGNN_04056 3.6e-56 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HAGICGNN_04057 1.5e-134 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HAGICGNN_04058 4.7e-119 ggaA M Glycosyltransferase like family 2
HAGICGNN_04059 2.9e-80
HAGICGNN_04060 6.7e-138 M Glycosyltransferase like family 2
HAGICGNN_04061 1e-168 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HAGICGNN_04062 4.2e-131 tagG GM Transport permease protein
HAGICGNN_04063 6.2e-264 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HAGICGNN_04064 1e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HAGICGNN_04065 1.7e-23 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HAGICGNN_04066 2.5e-97 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HAGICGNN_04067 6.2e-88 M Glycosyltransferase like family 2
HAGICGNN_04068 2.9e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HAGICGNN_04069 4.4e-153 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HAGICGNN_04070 1.2e-12
HAGICGNN_04071 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HAGICGNN_04072 1.9e-206 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HAGICGNN_04073 8.4e-98 M Glycosyltransferase like family 2
HAGICGNN_04074 3.5e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HAGICGNN_04075 1.7e-239 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HAGICGNN_04076 5.7e-206 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HAGICGNN_04077 6.7e-254 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HAGICGNN_04078 1.9e-251 tuaE M Teichuronic acid biosynthesis protein
HAGICGNN_04079 5.8e-110 tuaF M protein involved in exopolysaccharide biosynthesis
HAGICGNN_04080 2.5e-138 tuaG GT2 M Glycosyltransferase like family 2
HAGICGNN_04081 2.1e-224 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HAGICGNN_04082 3.2e-179 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HAGICGNN_04083 8.6e-159 yvhJ K Transcriptional regulator
HAGICGNN_04084 5e-119 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HAGICGNN_04085 1.1e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HAGICGNN_04086 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HAGICGNN_04087 9.9e-152 degV S protein conserved in bacteria
HAGICGNN_04088 1.7e-238 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HAGICGNN_04089 2e-43 comFB S Late competence development protein ComFB
HAGICGNN_04090 6.3e-115 comFC S Phosphoribosyl transferase domain
HAGICGNN_04091 3.1e-69 yvyF S flagellar protein
HAGICGNN_04092 7.5e-37 flgM KNU Negative regulator of flagellin synthesis
HAGICGNN_04093 2.8e-74 flgN NOU FlgN protein
HAGICGNN_04094 5.8e-251 flgK N flagellar hook-associated protein
HAGICGNN_04095 8.9e-151 flgL N Belongs to the bacterial flagellin family
HAGICGNN_04096 5.4e-45 yviE
HAGICGNN_04097 2e-68 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HAGICGNN_04098 2.2e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HAGICGNN_04099 5e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAGICGNN_04100 2.2e-54 flaG N flagellar protein FlaG
HAGICGNN_04101 9.5e-10 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAGICGNN_04102 2.2e-222 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HAGICGNN_04103 1e-66 fliS N flagellar protein FliS
HAGICGNN_04104 1.9e-08 fliT S bacterial-type flagellum organization
HAGICGNN_04105 9.2e-65
HAGICGNN_04107 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HAGICGNN_04108 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HAGICGNN_04109 2.3e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HAGICGNN_04110 1.5e-136 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HAGICGNN_04111 1.5e-53 cccB C COG2010 Cytochrome c, mono- and diheme variants
HAGICGNN_04112 4.3e-121 ftsE D cell division ATP-binding protein FtsE
HAGICGNN_04113 3.9e-154 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HAGICGNN_04114 2.9e-260 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HAGICGNN_04115 4.5e-55 swrA S Swarming motility protein
HAGICGNN_04116 4.4e-206 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HAGICGNN_04117 1.6e-220 yvkA EGP Major facilitator Superfamily
HAGICGNN_04118 4.4e-95 yvkB K Transcriptional regulator
HAGICGNN_04119 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HAGICGNN_04121 1.2e-30 csbA S protein conserved in bacteria
HAGICGNN_04122 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HAGICGNN_04123 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HAGICGNN_04124 3.9e-108 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HAGICGNN_04125 5.3e-31 yvkN
HAGICGNN_04126 4.4e-47 yvlA
HAGICGNN_04127 5.6e-163 yvlB S Putative adhesin
HAGICGNN_04128 1.3e-25 pspB KT PspC domain
HAGICGNN_04129 1.2e-50 yvlD S Membrane
HAGICGNN_04130 6e-44 L transposase activity

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)