ORF_ID e_value Gene_name EC_number CAZy COGs Description
DFEMHAFP_00001 6.1e-282 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DFEMHAFP_00002 3e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
DFEMHAFP_00003 1.3e-235 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DFEMHAFP_00004 6.2e-90 S Protein of unknown function (DUF721)
DFEMHAFP_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFEMHAFP_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DFEMHAFP_00007 3.3e-68 S Transmembrane domain of unknown function (DUF3566)
DFEMHAFP_00008 1.2e-260 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
DFEMHAFP_00009 6.1e-56 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
DFEMHAFP_00013 3.1e-101 S Protein of unknown function DUF45
DFEMHAFP_00014 1.3e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
DFEMHAFP_00015 2.8e-241 ytfL P Transporter associated domain
DFEMHAFP_00016 2e-118 cah 4.2.1.1 P Reversible hydration of carbon dioxide
DFEMHAFP_00017 5e-181
DFEMHAFP_00018 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DFEMHAFP_00019 0.0 yjjP S Threonine/Serine exporter, ThrE
DFEMHAFP_00020 9.4e-300 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DFEMHAFP_00021 5.9e-205 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFEMHAFP_00022 1.4e-41 S Protein of unknown function (DUF3073)
DFEMHAFP_00023 1.4e-62 I Sterol carrier protein
DFEMHAFP_00024 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
DFEMHAFP_00025 1.5e-35
DFEMHAFP_00026 2.8e-148 gluP 3.4.21.105 S Rhomboid family
DFEMHAFP_00027 2.5e-240 L ribosomal rna small subunit methyltransferase
DFEMHAFP_00028 3.1e-57 crgA D Involved in cell division
DFEMHAFP_00029 2.6e-141 S Bacterial protein of unknown function (DUF881)
DFEMHAFP_00030 6.7e-209 srtA 3.4.22.70 M Sortase family
DFEMHAFP_00031 8.7e-116 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
DFEMHAFP_00032 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
DFEMHAFP_00033 5.8e-177 T Protein tyrosine kinase
DFEMHAFP_00034 9.8e-264 pbpA M penicillin-binding protein
DFEMHAFP_00035 8.3e-274 rodA D Belongs to the SEDS family
DFEMHAFP_00036 6.8e-242 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
DFEMHAFP_00037 9.6e-73 fhaB T Inner membrane component of T3SS, cytoplasmic domain
DFEMHAFP_00038 1.2e-131 fhaA T Protein of unknown function (DUF2662)
DFEMHAFP_00039 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
DFEMHAFP_00040 3.5e-225 2.7.13.3 T Histidine kinase
DFEMHAFP_00041 7.8e-112 K helix_turn_helix, Lux Regulon
DFEMHAFP_00042 2.7e-191 pldB 3.1.1.5 I Serine aminopeptidase, S33
DFEMHAFP_00043 3.2e-162 yicL EG EamA-like transporter family
DFEMHAFP_00044 5.4e-86 XK27_10430 S NAD(P)H-binding
DFEMHAFP_00045 4.6e-44 ydeP K HxlR-like helix-turn-helix
DFEMHAFP_00047 9.4e-269 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
DFEMHAFP_00048 2.1e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
DFEMHAFP_00049 0.0 cadA P E1-E2 ATPase
DFEMHAFP_00050 3e-187 ansA 3.5.1.1 EJ Asparaginase
DFEMHAFP_00051 1.5e-269 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
DFEMHAFP_00052 6.8e-161 htpX O Belongs to the peptidase M48B family
DFEMHAFP_00054 9.4e-65 K Helix-turn-helix XRE-family like proteins
DFEMHAFP_00055 1.2e-169 yddG EG EamA-like transporter family
DFEMHAFP_00056 0.0 pip S YhgE Pip domain protein
DFEMHAFP_00057 0.0 pip S YhgE Pip domain protein
DFEMHAFP_00058 1.6e-205 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
DFEMHAFP_00059 1.6e-249 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DFEMHAFP_00060 1.2e-296 clcA P Voltage gated chloride channel
DFEMHAFP_00061 3.7e-155 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFEMHAFP_00062 3.3e-57 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFEMHAFP_00063 1.4e-29 E Receptor family ligand binding region
DFEMHAFP_00064 1.1e-195 K helix_turn _helix lactose operon repressor
DFEMHAFP_00065 1.2e-296 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
DFEMHAFP_00066 4.9e-10 S Protein of unknown function, DUF624
DFEMHAFP_00067 4.3e-265 scrT G Transporter major facilitator family protein
DFEMHAFP_00068 1.6e-241 yhjE EGP Sugar (and other) transporter
DFEMHAFP_00069 1.5e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DFEMHAFP_00070 3.4e-202 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DFEMHAFP_00071 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DFEMHAFP_00072 1.8e-154 E GDSL-like Lipase/Acylhydrolase family
DFEMHAFP_00073 5.9e-255 bglA 3.2.1.21 G Glycosyl hydrolase family 1
DFEMHAFP_00074 8.1e-220 G Bacterial extracellular solute-binding protein
DFEMHAFP_00075 2e-170 ycjO_3 U Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00076 6.4e-141 malG U Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00077 0.0 3.2.1.25 G beta-mannosidase
DFEMHAFP_00078 3.3e-181 K helix_turn _helix lactose operon repressor
DFEMHAFP_00079 2.4e-83 S Protein of unknown function, DUF624
DFEMHAFP_00080 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DFEMHAFP_00081 1.9e-101
DFEMHAFP_00082 2.7e-269 aroP E aromatic amino acid transport protein AroP K03293
DFEMHAFP_00083 0.0 V FtsX-like permease family
DFEMHAFP_00084 7.5e-227 P Sodium/hydrogen exchanger family
DFEMHAFP_00085 1.3e-76 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00086 4e-177 3.4.22.70 M Sortase family
DFEMHAFP_00087 0.0 inlJ M domain protein
DFEMHAFP_00088 2.6e-187 M LPXTG cell wall anchor motif
DFEMHAFP_00089 2.5e-89 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00090 9.9e-275 cycA E Amino acid permease
DFEMHAFP_00092 1.2e-166 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
DFEMHAFP_00093 6.5e-128 thiF 2.7.7.73, 2.7.7.80 H ThiF family
DFEMHAFP_00094 2.4e-24 thiS 2.8.1.10 H ThiS family
DFEMHAFP_00095 2e-156 1.1.1.65 C Aldo/keto reductase family
DFEMHAFP_00096 1.2e-56 ydgJ K helix_turn_helix multiple antibiotic resistance protein
DFEMHAFP_00097 5.1e-284 lmrA1 V ABC transporter, ATP-binding protein
DFEMHAFP_00098 5e-302 lmrA2 V ABC transporter transmembrane region
DFEMHAFP_00099 3.4e-122 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
DFEMHAFP_00100 4e-238 G MFS/sugar transport protein
DFEMHAFP_00101 9.8e-295 efeU_1 P Iron permease FTR1 family
DFEMHAFP_00102 1.4e-92 tpd P Fe2+ transport protein
DFEMHAFP_00103 3.2e-231 S Predicted membrane protein (DUF2318)
DFEMHAFP_00104 8e-220 macB_2 V ABC transporter permease
DFEMHAFP_00105 2.2e-201 Z012_06715 V FtsX-like permease family
DFEMHAFP_00106 9e-150 macB V ABC transporter, ATP-binding protein
DFEMHAFP_00107 1.1e-61 S FMN_bind
DFEMHAFP_00108 7.8e-88 K Psort location Cytoplasmic, score 8.87
DFEMHAFP_00109 1.8e-274 pip S YhgE Pip domain protein
DFEMHAFP_00110 0.0 pip S YhgE Pip domain protein
DFEMHAFP_00111 2.7e-225 S Putative ABC-transporter type IV
DFEMHAFP_00112 6e-38 nrdH O Glutaredoxin
DFEMHAFP_00113 1.4e-267 M cell wall binding repeat
DFEMHAFP_00115 2.5e-308 pepD E Peptidase family C69
DFEMHAFP_00116 4e-195 XK27_01805 M Glycosyltransferase like family 2
DFEMHAFP_00117 4.9e-108 icaR K Bacterial regulatory proteins, tetR family
DFEMHAFP_00118 7.3e-167 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
DFEMHAFP_00119 1.2e-236 amt U Ammonium Transporter Family
DFEMHAFP_00120 1e-54 glnB K Nitrogen regulatory protein P-II
DFEMHAFP_00121 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
DFEMHAFP_00122 3.3e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
DFEMHAFP_00123 3.9e-252 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
DFEMHAFP_00124 2.1e-137 cobQ S CobB/CobQ-like glutamine amidotransferase domain
DFEMHAFP_00125 1e-27 S granule-associated protein
DFEMHAFP_00126 0.0 ubiB S ABC1 family
DFEMHAFP_00127 6.3e-193 K Periplasmic binding protein domain
DFEMHAFP_00128 1.1e-242 G Bacterial extracellular solute-binding protein
DFEMHAFP_00129 4.3e-07 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00130 3.1e-167 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00131 9.3e-147 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00132 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DFEMHAFP_00133 0.0 sca1 3.2.1.187 GH121 DG Bacterial Ig-like domain (group 4)
DFEMHAFP_00134 0.0 G Bacterial Ig-like domain (group 4)
DFEMHAFP_00135 3.6e-207 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
DFEMHAFP_00136 1e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DFEMHAFP_00137 3.9e-91
DFEMHAFP_00138 4.5e-224 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
DFEMHAFP_00139 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DFEMHAFP_00141 5.5e-141 cpaE D bacterial-type flagellum organization
DFEMHAFP_00142 2.7e-185 cpaF U Type II IV secretion system protein
DFEMHAFP_00143 1.4e-125 U Type ii secretion system
DFEMHAFP_00144 7.4e-89 gspF NU Type II secretion system (T2SS), protein F
DFEMHAFP_00145 1.3e-42 S Protein of unknown function (DUF4244)
DFEMHAFP_00146 5.1e-60 U TadE-like protein
DFEMHAFP_00147 2.6e-54 S TIGRFAM helicase secretion neighborhood TadE-like protein
DFEMHAFP_00148 1.9e-214 dagK 2.7.1.107 I Diacylglycerol kinase catalytic domain protein
DFEMHAFP_00149 1.6e-193 S Psort location CytoplasmicMembrane, score
DFEMHAFP_00150 1.1e-96 K Bacterial regulatory proteins, tetR family
DFEMHAFP_00151 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
DFEMHAFP_00152 1e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DFEMHAFP_00153 3.4e-135 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
DFEMHAFP_00154 1.4e-96 askB 1.1.1.3, 2.7.2.4 E ACT domain
DFEMHAFP_00155 1.8e-209 asd 1.2.1.11, 1.2.1.12 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DFEMHAFP_00156 2.7e-48 yitI S Acetyltransferase (GNAT) domain
DFEMHAFP_00157 2.4e-115
DFEMHAFP_00158 1.5e-302 S Calcineurin-like phosphoesterase
DFEMHAFP_00159 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DFEMHAFP_00160 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DFEMHAFP_00161 0.0 3.2.1.99 GH43 G C-terminal of Glycosyl hydrolases family 43
DFEMHAFP_00162 0.0 3.2.1.97 GH101 G Glycosyl hydrolases family 43
DFEMHAFP_00163 1.1e-195 K helix_turn _helix lactose operon repressor
DFEMHAFP_00164 1.3e-203 abf G Glycosyl hydrolases family 43
DFEMHAFP_00165 8.2e-246 G Bacterial extracellular solute-binding protein
DFEMHAFP_00166 9.1e-170 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00167 1.9e-156 U Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00168 0.0 S Beta-L-arabinofuranosidase, GH127
DFEMHAFP_00169 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DFEMHAFP_00170 2.7e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
DFEMHAFP_00171 5.9e-235 glf 5.4.99.9 M UDP-galactopyranose mutase
DFEMHAFP_00172 6.7e-191 3.6.1.27 I PAP2 superfamily
DFEMHAFP_00173 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DFEMHAFP_00174 1.6e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DFEMHAFP_00175 5.4e-193 holB 2.7.7.7 L DNA polymerase III
DFEMHAFP_00176 3.7e-185 K helix_turn _helix lactose operon repressor
DFEMHAFP_00177 6e-39 ptsH G PTS HPr component phosphorylation site
DFEMHAFP_00178 9.5e-292 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DFEMHAFP_00179 1.1e-106 S Phosphatidylethanolamine-binding protein
DFEMHAFP_00180 0.0 pepD E Peptidase family C69
DFEMHAFP_00181 9.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
DFEMHAFP_00182 2.3e-62 S Macrophage migration inhibitory factor (MIF)
DFEMHAFP_00183 4.9e-96 S GtrA-like protein
DFEMHAFP_00184 2.1e-263 EGP Major facilitator Superfamily
DFEMHAFP_00185 1.5e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
DFEMHAFP_00186 7e-184
DFEMHAFP_00187 4.2e-112 S Protein of unknown function (DUF805)
DFEMHAFP_00188 5.5e-297 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DFEMHAFP_00191 4.3e-267 S Calcineurin-like phosphoesterase
DFEMHAFP_00192 1.1e-139 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
DFEMHAFP_00193 7.1e-272 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFEMHAFP_00194 1.3e-131 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DFEMHAFP_00195 3.6e-200 pyrD 1.3.1.14, 1.3.98.1 F Dihydroorotate dehydrogenase
DFEMHAFP_00196 1e-256 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DFEMHAFP_00197 3e-175 plsC2 2.3.1.51 I Phosphate acyltransferases
DFEMHAFP_00198 1.7e-179 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
DFEMHAFP_00199 3.7e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
DFEMHAFP_00200 2.6e-176 S CAAX protease self-immunity
DFEMHAFP_00201 1.7e-137 M Mechanosensitive ion channel
DFEMHAFP_00202 5.9e-230 MA20_36090 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00203 2.4e-228 MA20_36090 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00204 6.3e-125 K Bacterial regulatory proteins, tetR family
DFEMHAFP_00205 1.4e-231 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
DFEMHAFP_00206 8.8e-167 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase, C-terminal domain
DFEMHAFP_00208 6e-228 gnuT EG GntP family permease
DFEMHAFP_00209 1.1e-77 gntK 2.7.1.12 F Shikimate kinase
DFEMHAFP_00210 1.9e-127 gntR K FCD
DFEMHAFP_00211 4.9e-230 yxiO S Vacuole effluxer Atg22 like
DFEMHAFP_00212 0.0 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00213 8.4e-30 rpmB J Ribosomal L28 family
DFEMHAFP_00214 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
DFEMHAFP_00215 6.3e-86 rsmD 2.1.1.171 L Conserved hypothetical protein 95
DFEMHAFP_00216 1.5e-90 K helix_turn_helix, arabinose operon control protein
DFEMHAFP_00217 3.2e-138 uhpT EGP Major facilitator Superfamily
DFEMHAFP_00218 2.1e-148 I alpha/beta hydrolase fold
DFEMHAFP_00219 1.2e-148 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
DFEMHAFP_00220 4.4e-106 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DFEMHAFP_00221 1.8e-34 CP_0960 S Belongs to the UPF0109 family
DFEMHAFP_00222 3.9e-54 rpsP J Belongs to the bacterial ribosomal protein bS16 family
DFEMHAFP_00223 2.2e-177 S Endonuclease/Exonuclease/phosphatase family
DFEMHAFP_00224 2.7e-270 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DFEMHAFP_00225 9.3e-295 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFEMHAFP_00226 1.9e-152 guaA1 6.3.5.2 F Peptidase C26
DFEMHAFP_00227 0.0 yjjK S ABC transporter
DFEMHAFP_00228 7.9e-94
DFEMHAFP_00230 5.7e-92 ilvN 2.2.1.6 E ACT domain
DFEMHAFP_00231 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
DFEMHAFP_00232 5.7e-136 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
DFEMHAFP_00233 1e-19 rpmF J Belongs to the bacterial ribosomal protein bL32 family
DFEMHAFP_00234 1.5e-112 yceD S Uncharacterized ACR, COG1399
DFEMHAFP_00235 8e-132
DFEMHAFP_00236 7.7e-88 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DFEMHAFP_00237 4.2e-58 S Protein of unknown function (DUF3039)
DFEMHAFP_00238 1.7e-195 yghZ C Aldo/keto reductase family
DFEMHAFP_00239 3.2e-77 soxR K MerR, DNA binding
DFEMHAFP_00240 3.6e-120 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DFEMHAFP_00241 1e-139 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DFEMHAFP_00242 1.7e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DFEMHAFP_00243 4.9e-219 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DFEMHAFP_00244 9.1e-221 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
DFEMHAFP_00247 5.4e-181 S Auxin Efflux Carrier
DFEMHAFP_00248 0.0 pgi 5.3.1.9 G Belongs to the GPI family
DFEMHAFP_00249 3e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
DFEMHAFP_00250 1.1e-123 lepB 3.4.21.89 U Belongs to the peptidase S26 family
DFEMHAFP_00251 2.1e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFEMHAFP_00252 5e-128 V ATPases associated with a variety of cellular activities
DFEMHAFP_00253 2.5e-270 V Efflux ABC transporter, permease protein
DFEMHAFP_00254 2.7e-166 mdcF S Transporter, auxin efflux carrier (AEC) family protein
DFEMHAFP_00255 5.3e-231 dapE 3.5.1.18 E Peptidase dimerisation domain
DFEMHAFP_00256 1.5e-308 rne 3.1.26.12 J Ribonuclease E/G family
DFEMHAFP_00257 2.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
DFEMHAFP_00258 2.6e-39 rpmA J Ribosomal L27 protein
DFEMHAFP_00259 2.3e-311 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DFEMHAFP_00260 1e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DFEMHAFP_00261 9.7e-233 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
DFEMHAFP_00263 1.2e-32 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
DFEMHAFP_00264 1.7e-124 nusG K Participates in transcription elongation, termination and antitermination
DFEMHAFP_00265 2.3e-72 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DFEMHAFP_00266 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
DFEMHAFP_00267 4.3e-141 QT PucR C-terminal helix-turn-helix domain
DFEMHAFP_00268 0.0
DFEMHAFP_00269 3.2e-143 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
DFEMHAFP_00270 1.5e-77 bioY S BioY family
DFEMHAFP_00271 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
DFEMHAFP_00272 0.0 pccB I Carboxyl transferase domain
DFEMHAFP_00273 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
DFEMHAFP_00275 1.2e-82 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
DFEMHAFP_00276 0.0 ams 2.4.1.4, 3.2.1.1, 5.4.99.16 GH13 G Alpha amylase, catalytic domain
DFEMHAFP_00278 2.4e-116
DFEMHAFP_00279 1.7e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DFEMHAFP_00280 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
DFEMHAFP_00281 5e-91 lemA S LemA family
DFEMHAFP_00282 0.0 S Predicted membrane protein (DUF2207)
DFEMHAFP_00283 1.3e-170 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
DFEMHAFP_00284 7e-297 yegQ O Peptidase family U32 C-terminal domain
DFEMHAFP_00285 5.3e-184 yfiH Q Multi-copper polyphenol oxidoreductase laccase
DFEMHAFP_00286 2.4e-150 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
DFEMHAFP_00287 3.4e-126 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DFEMHAFP_00288 1.3e-58 D nuclear chromosome segregation
DFEMHAFP_00289 5.1e-267 pepC 3.4.22.40 E Peptidase C1-like family
DFEMHAFP_00290 6.7e-212 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DFEMHAFP_00291 1.3e-221 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DFEMHAFP_00292 1.1e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DFEMHAFP_00293 1.4e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
DFEMHAFP_00294 3.4e-129 KT Transcriptional regulatory protein, C terminal
DFEMHAFP_00295 1.6e-197 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
DFEMHAFP_00296 3.4e-164 pstC P probably responsible for the translocation of the substrate across the membrane
DFEMHAFP_00297 4e-168 pstA P Phosphate transport system permease
DFEMHAFP_00298 3.6e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
DFEMHAFP_00299 1.8e-143 P Zinc-uptake complex component A periplasmic
DFEMHAFP_00300 1.3e-246 pbuO S Permease family
DFEMHAFP_00301 1.1e-87 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DFEMHAFP_00302 2.4e-36 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
DFEMHAFP_00303 4.7e-175 T Forkhead associated domain
DFEMHAFP_00304 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
DFEMHAFP_00305 7e-35
DFEMHAFP_00306 1.9e-92 flgA NO SAF
DFEMHAFP_00307 6.1e-30 fmdB S Putative regulatory protein
DFEMHAFP_00308 1.1e-100 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
DFEMHAFP_00309 3.3e-121 rimJ 2.3.1.128 J Acetyltransferase (GNAT) domain
DFEMHAFP_00310 4.7e-147
DFEMHAFP_00311 2.5e-46 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
DFEMHAFP_00315 5.5e-25 rpmG J Ribosomal protein L33
DFEMHAFP_00316 7.1e-204 murB 1.3.1.98 M Cell wall formation
DFEMHAFP_00317 4.8e-266 E aromatic amino acid transport protein AroP K03293
DFEMHAFP_00318 8.3e-59 fdxA C 4Fe-4S binding domain
DFEMHAFP_00319 1.2e-213 dapC E Aminotransferase class I and II
DFEMHAFP_00320 2.9e-36 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DFEMHAFP_00321 0.0 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_00322 3.4e-232 3.2.1.156 GH8 G CBM9 module, glycoside hydrolase family 8 protein and carbohydrate esterase family 4 protein K01238
DFEMHAFP_00323 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
DFEMHAFP_00324 4.8e-295 CE10 I Belongs to the type-B carboxylesterase lipase family
DFEMHAFP_00326 4.4e-223 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DFEMHAFP_00327 4.7e-252 M Bacterial capsule synthesis protein PGA_cap
DFEMHAFP_00328 9.4e-186 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DFEMHAFP_00329 9e-113 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
DFEMHAFP_00330 3.1e-122
DFEMHAFP_00331 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DFEMHAFP_00332 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DFEMHAFP_00333 3.4e-67 rpsI J Belongs to the universal ribosomal protein uS9 family
DFEMHAFP_00334 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFEMHAFP_00335 1.4e-76 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
DFEMHAFP_00336 2e-216 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
DFEMHAFP_00337 1.5e-239 EGP Major facilitator Superfamily
DFEMHAFP_00338 9.5e-197 Z012_01000 1.1.1.14, 1.1.1.9 C Zinc-binding dehydrogenase
DFEMHAFP_00339 2.1e-182 rhaR_1 K helix_turn_helix, arabinose operon control protein
DFEMHAFP_00340 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
DFEMHAFP_00341 5.2e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
DFEMHAFP_00342 2.3e-116 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DFEMHAFP_00343 1.4e-116 rplD J Forms part of the polypeptide exit tunnel
DFEMHAFP_00344 6.8e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
DFEMHAFP_00345 6.1e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DFEMHAFP_00346 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DFEMHAFP_00347 1.9e-56 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DFEMHAFP_00348 1e-97 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DFEMHAFP_00349 1.7e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DFEMHAFP_00350 5e-38 rpmC J Belongs to the universal ribosomal protein uL29 family
DFEMHAFP_00351 4.9e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DFEMHAFP_00352 3e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DFEMHAFP_00353 8.7e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DFEMHAFP_00354 7.5e-103 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DFEMHAFP_00355 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DFEMHAFP_00356 5.5e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DFEMHAFP_00357 3.8e-96 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DFEMHAFP_00358 3.3e-59 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DFEMHAFP_00359 1.2e-92 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DFEMHAFP_00360 3.4e-25 rpmD J Ribosomal protein L30p/L7e
DFEMHAFP_00361 3.7e-73 rplO J binds to the 23S rRNA
DFEMHAFP_00362 3.8e-238 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
DFEMHAFP_00363 5.5e-98 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
DFEMHAFP_00364 1.6e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DFEMHAFP_00365 8.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
DFEMHAFP_00366 3.3e-62 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DFEMHAFP_00367 1.9e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DFEMHAFP_00368 4.7e-185 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFEMHAFP_00369 1.3e-66 rplQ J Ribosomal protein L17
DFEMHAFP_00370 1.7e-182 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
DFEMHAFP_00372 2e-102
DFEMHAFP_00373 6.1e-191 nusA K Participates in both transcription termination and antitermination
DFEMHAFP_00374 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DFEMHAFP_00375 2.2e-69 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DFEMHAFP_00376 2.5e-187 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DFEMHAFP_00377 2e-217 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
DFEMHAFP_00378 2.9e-252 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DFEMHAFP_00379 3.8e-108
DFEMHAFP_00381 3.1e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DFEMHAFP_00382 3.9e-213 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DFEMHAFP_00383 5.7e-250 T GHKL domain
DFEMHAFP_00384 2.8e-151 T LytTr DNA-binding domain
DFEMHAFP_00385 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
DFEMHAFP_00386 0.0 crr G pts system, glucose-specific IIABC component
DFEMHAFP_00387 2.8e-157 arbG K CAT RNA binding domain
DFEMHAFP_00388 8.3e-199 I Diacylglycerol kinase catalytic domain
DFEMHAFP_00389 1.2e-247 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DFEMHAFP_00391 4.6e-188 yegU O ADP-ribosylglycohydrolase
DFEMHAFP_00392 8.3e-190 yegV G pfkB family carbohydrate kinase
DFEMHAFP_00393 1.1e-270 U Permease for cytosine/purines, uracil, thiamine, allantoin
DFEMHAFP_00394 1.5e-103 Q Isochorismatase family
DFEMHAFP_00395 2.3e-214 S Choline/ethanolamine kinase
DFEMHAFP_00396 1.6e-274 eat E Amino acid permease
DFEMHAFP_00397 5.3e-264 gabT 2.6.1.19, 2.6.1.22 H Aminotransferase class-III
DFEMHAFP_00398 5.6e-141 yidP K UTRA
DFEMHAFP_00399 1.3e-120 degU K helix_turn_helix, Lux Regulon
DFEMHAFP_00400 4.3e-257 tcsS3 KT PspC domain
DFEMHAFP_00401 4.9e-146 pspC KT PspC domain
DFEMHAFP_00402 1.3e-91
DFEMHAFP_00403 7.4e-115 S Protein of unknown function (DUF4125)
DFEMHAFP_00404 0.0 S Domain of unknown function (DUF4037)
DFEMHAFP_00405 9.8e-214 araJ EGP Major facilitator Superfamily
DFEMHAFP_00407 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
DFEMHAFP_00408 1.3e-190 K helix_turn _helix lactose operon repressor
DFEMHAFP_00409 7.4e-250 G Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_00410 4.1e-99 S Serine aminopeptidase, S33
DFEMHAFP_00411 1.1e-206 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
DFEMHAFP_00412 2.9e-139 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DFEMHAFP_00413 0.0 4.2.1.53 S MCRA family
DFEMHAFP_00414 3.3e-89 phoU P Plays a role in the regulation of phosphate uptake
DFEMHAFP_00415 2.4e-215 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFEMHAFP_00416 6.2e-41
DFEMHAFP_00417 8.2e-218 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DFEMHAFP_00418 1.3e-165 usp 3.5.1.28 CBM50 S CHAP domain
DFEMHAFP_00419 1.5e-93 M NlpC/P60 family
DFEMHAFP_00420 7.3e-189 T Universal stress protein family
DFEMHAFP_00421 1e-72 attW O OsmC-like protein
DFEMHAFP_00422 8.4e-181 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DFEMHAFP_00423 1.9e-126 folA 1.5.1.3 H dihydrofolate reductase
DFEMHAFP_00424 0.0 tetP J elongation factor G
DFEMHAFP_00425 2.1e-85 ptpA 3.1.3.48 T low molecular weight
DFEMHAFP_00427 9e-200 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
DFEMHAFP_00428 2.9e-170 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
DFEMHAFP_00432 0.0 5.1.3.2 GM ADP-glyceromanno-heptose 6-epimerase activity
DFEMHAFP_00433 2e-161
DFEMHAFP_00434 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
DFEMHAFP_00435 2.3e-281 pelF GT4 M Domain of unknown function (DUF3492)
DFEMHAFP_00436 2.1e-285 pelG S Putative exopolysaccharide Exporter (EPS-E)
DFEMHAFP_00437 1.6e-308 cotH M CotH kinase protein
DFEMHAFP_00438 1.4e-158 P VTC domain
DFEMHAFP_00439 2.2e-111 S Domain of unknown function (DUF4956)
DFEMHAFP_00440 0.0 yliE T Putative diguanylate phosphodiesterase
DFEMHAFP_00441 1.8e-204 fucO 1.1.1.1, 1.1.1.77, 1.1.99.37, 1.2.98.1 C Iron-containing alcohol dehydrogenase
DFEMHAFP_00442 5.5e-180 3.4.14.13 M Glycosyltransferase like family 2
DFEMHAFP_00443 1.2e-232 S AI-2E family transporter
DFEMHAFP_00444 3.1e-231 epsG M Glycosyl transferase family 21
DFEMHAFP_00445 4.7e-234 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
DFEMHAFP_00446 9.7e-200 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
DFEMHAFP_00447 3.9e-99 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
DFEMHAFP_00448 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DFEMHAFP_00449 9.6e-115 folE 2.7.6.3, 3.5.4.16 H GTP cyclohydrolase
DFEMHAFP_00450 2.2e-154 folP 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DFEMHAFP_00451 1.3e-263 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 3.5.4.39, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DFEMHAFP_00452 1.8e-93 S Protein of unknown function (DUF3180)
DFEMHAFP_00453 1.1e-164 tesB I Thioesterase-like superfamily
DFEMHAFP_00454 0.0 yjjK S ATP-binding cassette protein, ChvD family
DFEMHAFP_00455 1.7e-181 V Beta-lactamase
DFEMHAFP_00456 3.3e-71 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
DFEMHAFP_00457 5.2e-165 ribD 1.1.1.193, 3.5.4.26 H Cytidine and deoxycytidylate deaminase zinc-binding region
DFEMHAFP_00459 2.5e-77 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
DFEMHAFP_00460 1.3e-295 S Amidohydrolase family
DFEMHAFP_00461 2.2e-251 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
DFEMHAFP_00462 3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
DFEMHAFP_00463 0.0 3.2.1.37, 3.2.1.55 GH43,GH51 G Belongs to the glycosyl hydrolase 43 family
DFEMHAFP_00464 4.5e-183 K Bacterial regulatory proteins, lacI family
DFEMHAFP_00465 5.4e-242 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
DFEMHAFP_00466 3.4e-186 MA20_14025 U Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00467 2.4e-164 MA20_14020 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00468 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
DFEMHAFP_00469 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
DFEMHAFP_00470 6.7e-10 CE10 I Belongs to the type-B carboxylesterase lipase family
DFEMHAFP_00471 2.8e-106 lacA 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DFEMHAFP_00472 9.4e-286 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DFEMHAFP_00473 1.7e-224 xylR GK ROK family
DFEMHAFP_00475 1.5e-35 rpmE J Binds the 23S rRNA
DFEMHAFP_00476 1.4e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DFEMHAFP_00477 3.2e-172 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
DFEMHAFP_00478 7.8e-219 livK E Receptor family ligand binding region
DFEMHAFP_00479 9.5e-156 U Belongs to the binding-protein-dependent transport system permease family
DFEMHAFP_00480 5.1e-196 livM U Belongs to the binding-protein-dependent transport system permease family
DFEMHAFP_00481 4.8e-151 E Branched-chain amino acid ATP-binding cassette transporter
DFEMHAFP_00482 1.9e-124 livF E ATPases associated with a variety of cellular activities
DFEMHAFP_00483 3.8e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
DFEMHAFP_00484 1.3e-194 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
DFEMHAFP_00485 2.2e-287 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
DFEMHAFP_00486 1.6e-120 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DFEMHAFP_00487 5e-162 supH S Sucrose-6F-phosphate phosphohydrolase
DFEMHAFP_00488 1e-270 recD2 3.6.4.12 L PIF1-like helicase
DFEMHAFP_00489 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DFEMHAFP_00490 5.2e-98 L Single-strand binding protein family
DFEMHAFP_00491 0.0 pepO 3.4.24.71 O Peptidase family M13
DFEMHAFP_00492 1.6e-151 map 3.4.11.18 E Methionine aminopeptidase
DFEMHAFP_00493 2.1e-249 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
DFEMHAFP_00494 5.8e-143 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
DFEMHAFP_00495 1.2e-80 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DFEMHAFP_00496 3.2e-190 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DFEMHAFP_00497 8.9e-168 ftsE D Cell division ATP-binding protein FtsE
DFEMHAFP_00498 3.4e-161 ftsX D Part of the ABC transporter FtsEX involved in cellular division
DFEMHAFP_00499 1.7e-148 usp 3.5.1.28 CBM50 D CHAP domain protein
DFEMHAFP_00500 2e-77 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
DFEMHAFP_00501 3.3e-156 pknD ET ABC transporter, substrate-binding protein, family 3
DFEMHAFP_00502 1e-35 pknD ET ABC transporter, substrate-binding protein, family 3
DFEMHAFP_00503 8.6e-149 pknD ET ABC transporter, substrate-binding protein, family 3
DFEMHAFP_00504 1.9e-125 yecS E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00505 8.5e-145 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
DFEMHAFP_00506 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
DFEMHAFP_00507 1.9e-146 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
DFEMHAFP_00508 7.1e-49 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DFEMHAFP_00509 5.6e-164 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
DFEMHAFP_00510 1.4e-189 K Periplasmic binding protein domain
DFEMHAFP_00511 6.2e-163 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00512 1.2e-167 G ABC transporter permease
DFEMHAFP_00513 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_00514 2.2e-311 abfA1 3.2.1.55 GH51 G arabinose metabolic process
DFEMHAFP_00515 2.2e-246 G Bacterial extracellular solute-binding protein
DFEMHAFP_00516 1.1e-275 G Bacterial extracellular solute-binding protein
DFEMHAFP_00517 4.8e-122 K Transcriptional regulatory protein, C terminal
DFEMHAFP_00518 3.6e-143 T His Kinase A (phosphoacceptor) domain
DFEMHAFP_00519 7e-82 S SnoaL-like domain
DFEMHAFP_00520 3.8e-142 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DFEMHAFP_00521 1.8e-237 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DFEMHAFP_00522 1.3e-288 E ABC transporter, substrate-binding protein, family 5
DFEMHAFP_00523 1.7e-163 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00524 1.4e-135 EP Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00525 5.1e-134 oppD EP oligopeptide transport protein of the ABC superfamily, ATP-binding component
DFEMHAFP_00526 1.5e-138 sapF E ATPases associated with a variety of cellular activities
DFEMHAFP_00527 1.6e-185 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
DFEMHAFP_00528 3.5e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DFEMHAFP_00529 0.0 macB_2 V ATPases associated with a variety of cellular activities
DFEMHAFP_00530 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
DFEMHAFP_00531 3.9e-92 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
DFEMHAFP_00532 1.9e-103 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DFEMHAFP_00533 4.9e-268 yhdG E aromatic amino acid transport protein AroP K03293
DFEMHAFP_00534 2.1e-285 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DFEMHAFP_00535 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
DFEMHAFP_00536 7.3e-217 ybiR P Citrate transporter
DFEMHAFP_00538 0.0 tetP J Elongation factor G, domain IV
DFEMHAFP_00542 7.6e-109 yhcX S Acetyltransferase (GNAT) family
DFEMHAFP_00543 1.6e-109 papP E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00544 1.8e-119 E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00545 2e-149 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
DFEMHAFP_00546 1.1e-140 cjaA ET Bacterial periplasmic substrate-binding proteins
DFEMHAFP_00547 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_00548 3.7e-190 K Periplasmic binding protein domain
DFEMHAFP_00549 5.8e-233 G Bacterial extracellular solute-binding protein
DFEMHAFP_00550 1.1e-135 U Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00551 1.2e-157 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00552 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
DFEMHAFP_00553 0.0 ydcK 3.2.1.23, 5.4.2.9 JM Carbohydrate binding module (family 6)
DFEMHAFP_00554 5.4e-245 G Transporter major facilitator family protein
DFEMHAFP_00555 7.2e-197 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DFEMHAFP_00556 8.2e-141 metQ M NLPA lipoprotein
DFEMHAFP_00557 2.5e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DFEMHAFP_00558 1.2e-99 metI P Psort location CytoplasmicMembrane, score 9.99
DFEMHAFP_00559 1.2e-219 mtnE 2.6.1.83 E Aminotransferase class I and II
DFEMHAFP_00560 6.7e-73 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
DFEMHAFP_00561 4.1e-14 P Belongs to the ABC transporter superfamily
DFEMHAFP_00562 8.9e-43 XAC3035 O Glutaredoxin
DFEMHAFP_00563 9e-127 XK27_08050 O prohibitin homologues
DFEMHAFP_00564 2e-132 V ATPases associated with a variety of cellular activities
DFEMHAFP_00565 1.4e-148 M Conserved repeat domain
DFEMHAFP_00566 5.2e-257 macB_8 V MacB-like periplasmic core domain
DFEMHAFP_00567 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DFEMHAFP_00568 1.2e-183 adh3 C Zinc-binding dehydrogenase
DFEMHAFP_00569 1.1e-84 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DFEMHAFP_00570 6.4e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DFEMHAFP_00571 2.3e-89 zur P Belongs to the Fur family
DFEMHAFP_00572 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DFEMHAFP_00573 6.1e-202 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DFEMHAFP_00574 9.1e-189 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G pfkB family carbohydrate kinase
DFEMHAFP_00575 3.3e-129 trpF 5.3.1.24 E N-(5'phosphoribosyl)anthranilate (PRA) isomerase
DFEMHAFP_00576 3.3e-214 1.1.1.1 C Iron-containing alcohol dehydrogenase
DFEMHAFP_00577 1.1e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DFEMHAFP_00578 1.6e-247 EGP Major facilitator Superfamily
DFEMHAFP_00579 2.8e-235 purD 6.3.4.13 F Belongs to the GARS family
DFEMHAFP_00580 8.3e-185 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
DFEMHAFP_00581 1e-284 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DFEMHAFP_00582 2.5e-308 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
DFEMHAFP_00583 1.5e-33
DFEMHAFP_00584 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
DFEMHAFP_00585 1e-136 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
DFEMHAFP_00586 4.2e-215 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DFEMHAFP_00587 1.1e-222 M Glycosyl transferase 4-like domain
DFEMHAFP_00588 8.2e-193 ltaE 4.1.2.48 E Beta-eliminating lyase
DFEMHAFP_00590 8.1e-188 yocS S SBF-like CPA transporter family (DUF4137)
DFEMHAFP_00591 1.2e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DFEMHAFP_00592 3.3e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
DFEMHAFP_00593 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DFEMHAFP_00594 9.5e-233 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DFEMHAFP_00595 2e-103 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DFEMHAFP_00596 1.5e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DFEMHAFP_00597 7.4e-233 carA 6.3.5.5 F Belongs to the CarA family
DFEMHAFP_00598 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
DFEMHAFP_00599 3.7e-171 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DFEMHAFP_00600 1.2e-106 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
DFEMHAFP_00602 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
DFEMHAFP_00603 1.4e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
DFEMHAFP_00604 4.2e-228 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DFEMHAFP_00605 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DFEMHAFP_00606 2.7e-134 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DFEMHAFP_00607 2.4e-178 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DFEMHAFP_00608 1.6e-123 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
DFEMHAFP_00609 2.2e-282 arc O AAA ATPase forming ring-shaped complexes
DFEMHAFP_00610 5.7e-302 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
DFEMHAFP_00611 3.3e-160 hisN 3.1.3.25 G Inositol monophosphatase family
DFEMHAFP_00612 1.4e-24 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
DFEMHAFP_00613 1.1e-275 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DFEMHAFP_00614 9.7e-141 C FMN binding
DFEMHAFP_00615 3.9e-57
DFEMHAFP_00616 1.4e-41 hup L Belongs to the bacterial histone-like protein family
DFEMHAFP_00617 0.0 S Lysylphosphatidylglycerol synthase TM region
DFEMHAFP_00618 1.6e-279 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
DFEMHAFP_00619 1.6e-277 S PGAP1-like protein
DFEMHAFP_00620 1.3e-62
DFEMHAFP_00621 5e-182 S von Willebrand factor (vWF) type A domain
DFEMHAFP_00622 1.8e-190 S von Willebrand factor (vWF) type A domain
DFEMHAFP_00623 3.6e-91
DFEMHAFP_00624 1.2e-174 S Protein of unknown function DUF58
DFEMHAFP_00625 4e-182 moxR S ATPase family associated with various cellular activities (AAA)
DFEMHAFP_00626 4.4e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DFEMHAFP_00627 8.5e-77 S LytR cell envelope-related transcriptional attenuator
DFEMHAFP_00628 8.7e-290 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
DFEMHAFP_00630 3.9e-124
DFEMHAFP_00631 2.6e-132 KT Response regulator receiver domain protein
DFEMHAFP_00632 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFEMHAFP_00633 4.5e-67 cspB K 'Cold-shock' DNA-binding domain
DFEMHAFP_00634 2.6e-182 S Protein of unknown function (DUF3027)
DFEMHAFP_00635 4.6e-188 uspA T Belongs to the universal stress protein A family
DFEMHAFP_00636 0.0 clpC O ATPase family associated with various cellular activities (AAA)
DFEMHAFP_00637 4.4e-255 codA 3.5.4.1, 3.5.4.21 F Amidohydrolase family
DFEMHAFP_00638 2.3e-284 purR QT Purine catabolism regulatory protein-like family
DFEMHAFP_00639 5e-246 proP EGP Sugar (and other) transporter
DFEMHAFP_00640 3e-139 3.5.2.10 S Creatinine amidohydrolase
DFEMHAFP_00641 1.5e-216 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
DFEMHAFP_00642 5.3e-251 hisS 6.1.1.21 J Histidyl-tRNA synthetase
DFEMHAFP_00643 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DFEMHAFP_00644 7.1e-281 glnP E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00645 6.7e-139 glnQ 3.6.3.21 E ATPases associated with a variety of cellular activities
DFEMHAFP_00646 4.4e-144 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
DFEMHAFP_00647 3.1e-153 gluB ET Belongs to the bacterial solute-binding protein 3 family
DFEMHAFP_00648 1.8e-111 gluC E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00649 1.7e-199 gluD E Binding-protein-dependent transport system inner membrane component
DFEMHAFP_00650 1.3e-190 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
DFEMHAFP_00651 0.0 L DEAD DEAH box helicase
DFEMHAFP_00652 3.1e-251 rarA L Recombination factor protein RarA
DFEMHAFP_00653 4.8e-134 KT Transcriptional regulatory protein, C terminal
DFEMHAFP_00654 6.8e-287 mtrB 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
DFEMHAFP_00655 0.0 lpqB S Lipoprotein LpqB beta-propeller domain
DFEMHAFP_00656 2.4e-165 G Periplasmic binding protein domain
DFEMHAFP_00657 6e-288 ytfR 3.6.3.17 G ATPases associated with a variety of cellular activities
DFEMHAFP_00658 1.5e-181 ytfT U Branched-chain amino acid transport system / permease component
DFEMHAFP_00659 1.2e-172 yjfF U Branched-chain amino acid transport system / permease component
DFEMHAFP_00660 7.6e-251 EGP Major facilitator Superfamily
DFEMHAFP_00661 0.0 E ABC transporter, substrate-binding protein, family 5
DFEMHAFP_00662 1e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DFEMHAFP_00663 8.6e-125 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
DFEMHAFP_00664 6.1e-241 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DFEMHAFP_00667 3.9e-246 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DFEMHAFP_00668 4.8e-117 safC S O-methyltransferase
DFEMHAFP_00669 3.4e-177 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
DFEMHAFP_00670 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
DFEMHAFP_00671 4.5e-255 dprA 5.99.1.2 LU DNA recombination-mediator protein A
DFEMHAFP_00672 1e-292 comM O Magnesium chelatase, subunit ChlI C-terminal
DFEMHAFP_00673 3.1e-83 yraN L Belongs to the UPF0102 family
DFEMHAFP_00674 1.5e-166 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
DFEMHAFP_00675 5.9e-252 metY 2.5.1.49 E Aminotransferase class-V
DFEMHAFP_00676 4.3e-95 XK27_01265 S ECF-type riboflavin transporter, S component
DFEMHAFP_00677 4.3e-305 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
DFEMHAFP_00678 6.9e-150 P Cobalt transport protein
DFEMHAFP_00679 8.2e-193 K helix_turn_helix ASNC type
DFEMHAFP_00680 5.1e-142 V ABC transporter, ATP-binding protein
DFEMHAFP_00681 0.0 MV MacB-like periplasmic core domain
DFEMHAFP_00682 2.1e-129 K helix_turn_helix, Lux Regulon
DFEMHAFP_00683 0.0 tcsS2 T Histidine kinase
DFEMHAFP_00684 1.3e-267 pip 3.4.11.5 S alpha/beta hydrolase fold
DFEMHAFP_00685 1.6e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DFEMHAFP_00686 3.9e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
DFEMHAFP_00687 3.4e-17 yccF S Inner membrane component domain
DFEMHAFP_00688 5.9e-12
DFEMHAFP_00689 0.0 cysB 4.2.1.22 EGP Major facilitator Superfamily
DFEMHAFP_00690 8e-31 feoB P transporter of a GTP-driven Fe(2 ) uptake system
DFEMHAFP_00691 3.9e-94
DFEMHAFP_00692 1.1e-165 MA20_14895 S Conserved hypothetical protein 698
DFEMHAFP_00693 5.6e-186 C Na H antiporter family protein
DFEMHAFP_00694 8.5e-157 korD 1.2.7.3 C Domain of unknown function (DUF362)
DFEMHAFP_00695 4.9e-79 2.7.1.48 F uridine kinase
DFEMHAFP_00696 1.5e-69 S ECF transporter, substrate-specific component
DFEMHAFP_00697 1.3e-143 S Sulfite exporter TauE/SafE
DFEMHAFP_00698 1.5e-135 K helix_turn_helix, arabinose operon control protein
DFEMHAFP_00699 1.4e-155 3.1.3.73 G Phosphoglycerate mutase family
DFEMHAFP_00700 2.9e-227 rutG F Permease family
DFEMHAFP_00701 6e-126 S Enoyl-(Acyl carrier protein) reductase
DFEMHAFP_00702 6e-275 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
DFEMHAFP_00703 1.8e-134 ybbM V Uncharacterised protein family (UPF0014)
DFEMHAFP_00704 2.4e-142 ybbL V ATPases associated with a variety of cellular activities
DFEMHAFP_00705 7.7e-242 S Putative esterase
DFEMHAFP_00706 0.0 lysX S Uncharacterised conserved protein (DUF2156)
DFEMHAFP_00707 1.2e-277 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DFEMHAFP_00708 1e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
DFEMHAFP_00709 4.8e-237 patB 4.4.1.8 E Aminotransferase, class I II
DFEMHAFP_00710 3.9e-303 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DFEMHAFP_00711 2.6e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
DFEMHAFP_00712 3.4e-146 pgl 3.1.1.31, 3.5.99.6 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
DFEMHAFP_00713 1.6e-82 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DFEMHAFP_00714 3.9e-87 M Protein of unknown function (DUF3737)
DFEMHAFP_00715 1.1e-134 azlC E AzlC protein
DFEMHAFP_00716 3.2e-53 azlD E Branched-chain amino acid transport protein (AzlD)
DFEMHAFP_00717 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
DFEMHAFP_00718 6.2e-40 ybdD S Selenoprotein, putative
DFEMHAFP_00719 4.8e-179 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
DFEMHAFP_00720 0.0 S Uncharacterised protein family (UPF0182)
DFEMHAFP_00721 3.6e-99 2.3.1.183 M Acetyltransferase (GNAT) domain
DFEMHAFP_00722 1.7e-113 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
DFEMHAFP_00723 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DFEMHAFP_00724 1.5e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
DFEMHAFP_00725 9.8e-71 divIC D Septum formation initiator
DFEMHAFP_00726 2e-103 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
DFEMHAFP_00727 4.4e-183 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DFEMHAFP_00729 3.5e-92
DFEMHAFP_00730 7.2e-283 sdaA 4.3.1.17 E Serine dehydratase alpha chain
DFEMHAFP_00731 1.2e-73 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
DFEMHAFP_00732 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
DFEMHAFP_00733 1.2e-142 yplQ S Haemolysin-III related
DFEMHAFP_00734 1.7e-276 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFEMHAFP_00735 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DFEMHAFP_00736 0.0 D FtsK/SpoIIIE family
DFEMHAFP_00737 6.9e-170 K Cell envelope-related transcriptional attenuator domain
DFEMHAFP_00739 5.7e-208 K Cell envelope-related transcriptional attenuator domain
DFEMHAFP_00740 3.4e-54 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
DFEMHAFP_00741 0.0 S Glycosyl transferase, family 2
DFEMHAFP_00742 8.7e-223
DFEMHAFP_00743 1.5e-71 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
DFEMHAFP_00744 1.2e-151 cof 5.2.1.8 T Eukaryotic phosphomannomutase
DFEMHAFP_00745 2.1e-137 ctsW S Phosphoribosyl transferase domain
DFEMHAFP_00746 6.8e-188 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
DFEMHAFP_00747 2e-129 T Response regulator receiver domain protein
DFEMHAFP_00748 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
DFEMHAFP_00749 3e-102 carD K CarD-like/TRCF domain
DFEMHAFP_00750 7.8e-88 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
DFEMHAFP_00751 1e-140 znuB U ABC 3 transport family
DFEMHAFP_00752 2e-160 znuC P ATPases associated with a variety of cellular activities
DFEMHAFP_00753 4.4e-176 P Zinc-uptake complex component A periplasmic
DFEMHAFP_00754 1.9e-161 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DFEMHAFP_00755 8.3e-255 rpsA J Ribosomal protein S1
DFEMHAFP_00756 9.1e-116 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DFEMHAFP_00757 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DFEMHAFP_00758 5.4e-14 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
DFEMHAFP_00759 3.3e-158 terC P Integral membrane protein, TerC family
DFEMHAFP_00760 2.5e-305 pyk 2.7.1.40 G Pyruvate kinase
DFEMHAFP_00762 1e-70 topB 5.99.1.2 L DNA topoisomerase
DFEMHAFP_00763 1.8e-15
DFEMHAFP_00766 7.6e-97 KL Type III restriction enzyme res subunit
DFEMHAFP_00767 7.3e-166 yeaD 4.2.1.9, 5.1.3.15 G Aldose 1-epimerase
DFEMHAFP_00768 1.9e-101 pdtaR T Response regulator receiver domain protein
DFEMHAFP_00769 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DFEMHAFP_00770 9.9e-174 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
DFEMHAFP_00771 1.5e-123 3.6.1.13 L NUDIX domain
DFEMHAFP_00772 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFEMHAFP_00773 1.4e-212 ykiI
DFEMHAFP_00775 7.9e-69 L Phage integrase family
DFEMHAFP_00776 2.9e-69 L Phage integrase family
DFEMHAFP_00777 2.5e-38
DFEMHAFP_00778 3.8e-115 XK27_00240 K Fic/DOC family
DFEMHAFP_00779 3.3e-111 polC_1 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DFEMHAFP_00780 1.2e-11 K Helix-turn-helix XRE-family like proteins
DFEMHAFP_00781 6.3e-14 K Cro/C1-type HTH DNA-binding domain
DFEMHAFP_00783 4.2e-07
DFEMHAFP_00784 3e-21
DFEMHAFP_00787 1.2e-49 ssb1 L Single-stranded DNA-binding protein
DFEMHAFP_00789 4.2e-19
DFEMHAFP_00791 2.7e-07
DFEMHAFP_00792 4.5e-28 K Transcriptional regulator
DFEMHAFP_00793 1.4e-25 V HNH endonuclease
DFEMHAFP_00794 1.4e-24 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
DFEMHAFP_00795 6.9e-22
DFEMHAFP_00796 2.6e-69
DFEMHAFP_00797 3.1e-60
DFEMHAFP_00798 1.3e-59
DFEMHAFP_00801 4.8e-16 V HNH nucleases
DFEMHAFP_00803 8.4e-118 S phage terminase, large subunit
DFEMHAFP_00804 4.6e-14 S Phage portal protein, SPP1 Gp6-like
DFEMHAFP_00805 7.9e-82 S Phage portal protein, SPP1 Gp6-like
DFEMHAFP_00807 5.9e-112
DFEMHAFP_00810 5.5e-65
DFEMHAFP_00812 2.3e-15 S Phage protein Gp19/Gp15/Gp42
DFEMHAFP_00813 2.9e-12
DFEMHAFP_00816 1.1e-28 eae N domain, Protein
DFEMHAFP_00819 2.7e-70 S Transglycosylase SLT domain
DFEMHAFP_00820 2.9e-35
DFEMHAFP_00821 2.8e-10
DFEMHAFP_00822 9.1e-129
DFEMHAFP_00823 1.3e-06 E GDSL-like Lipase/Acylhydrolase family
DFEMHAFP_00824 2.6e-37
DFEMHAFP_00827 1.4e-15 S Protein of unknown function (DUF2806)
DFEMHAFP_00829 2.5e-67 M Glycosyl hydrolases family 25
DFEMHAFP_00831 8.7e-251 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
DFEMHAFP_00832 4.5e-71 yvbK 3.1.3.25 K Acetyltransferase (GNAT) domain
DFEMHAFP_00833 2.2e-75 yiaC K Acetyltransferase (GNAT) domain
DFEMHAFP_00834 5.1e-303 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
DFEMHAFP_00835 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
DFEMHAFP_00836 3e-301 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
DFEMHAFP_00837 1.7e-232 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DFEMHAFP_00838 0.0 yrhL I Psort location CytoplasmicMembrane, score 9.99
DFEMHAFP_00839 9.5e-245 pbuX F Permease family
DFEMHAFP_00840 1.5e-106 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
DFEMHAFP_00841 0.0 pcrA 3.6.4.12 L DNA helicase
DFEMHAFP_00842 1.7e-61 S Domain of unknown function (DUF4418)
DFEMHAFP_00843 4.8e-216 V FtsX-like permease family
DFEMHAFP_00844 1.9e-150 lolD V ABC transporter
DFEMHAFP_00845 3.1e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DFEMHAFP_00846 3.4e-51 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
DFEMHAFP_00847 5.6e-129 pgm3 G Phosphoglycerate mutase family
DFEMHAFP_00848 3.4e-59 WQ51_05790 S Bacterial protein of unknown function (DUF948)
DFEMHAFP_00849 2.5e-36
DFEMHAFP_00850 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DFEMHAFP_00851 2.7e-82 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DFEMHAFP_00852 8.9e-191 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DFEMHAFP_00853 9.3e-57 3.4.23.43 S Type IV leader peptidase family
DFEMHAFP_00854 1.3e-221 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DFEMHAFP_00855 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DFEMHAFP_00856 4.9e-81 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
DFEMHAFP_00857 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 M Aamy_C
DFEMHAFP_00858 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
DFEMHAFP_00859 0.0 S L,D-transpeptidase catalytic domain
DFEMHAFP_00860 1.6e-290 sufB O FeS assembly protein SufB
DFEMHAFP_00861 3.9e-234 sufD O FeS assembly protein SufD
DFEMHAFP_00862 1e-142 sufC O FeS assembly ATPase SufC
DFEMHAFP_00863 1.7e-240 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DFEMHAFP_00864 3.4e-100 iscU C SUF system FeS assembly protein, NifU family
DFEMHAFP_00865 4e-107 yitW S Iron-sulfur cluster assembly protein
DFEMHAFP_00866 8.1e-243 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
DFEMHAFP_00867 3.5e-163 spoU 2.1.1.185 J SpoU rRNA Methylase family
DFEMHAFP_00869 2e-138 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
DFEMHAFP_00870 4.1e-56 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
DFEMHAFP_00871 1.3e-207 phoH T PhoH-like protein
DFEMHAFP_00872 9.4e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DFEMHAFP_00873 4.1e-251 corC S CBS domain
DFEMHAFP_00874 2e-180 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DFEMHAFP_00875 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DFEMHAFP_00876 1.7e-202 pntA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
DFEMHAFP_00877 1.6e-43 pntAA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
DFEMHAFP_00878 3.5e-258 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DFEMHAFP_00879 1.9e-269 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00881 2.1e-225 G Transmembrane secretion effector
DFEMHAFP_00882 3.5e-120 K Bacterial regulatory proteins, tetR family
DFEMHAFP_00884 1.1e-39 nrdH O Glutaredoxin
DFEMHAFP_00885 3.3e-74 nrdI F Probably involved in ribonucleotide reductase function
DFEMHAFP_00886 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFEMHAFP_00888 8.2e-190 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DFEMHAFP_00889 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DFEMHAFP_00890 1.3e-29 EGP Major facilitator Superfamily
DFEMHAFP_00891 1.3e-25 yhjX EGP Major facilitator Superfamily
DFEMHAFP_00892 3.8e-195 S alpha beta
DFEMHAFP_00893 1e-89 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DFEMHAFP_00894 6.3e-93 D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFEMHAFP_00895 3.2e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DFEMHAFP_00896 9.1e-74 K Acetyltransferase (GNAT) domain
DFEMHAFP_00898 1.9e-227 ilvE 2.6.1.42 E Amino-transferase class IV
DFEMHAFP_00899 1.1e-133 S UPF0126 domain
DFEMHAFP_00900 2.9e-33 rpsT J Binds directly to 16S ribosomal RNA
DFEMHAFP_00901 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
DFEMHAFP_00902 3.3e-233 hemN H Involved in the biosynthesis of porphyrin-containing compound
DFEMHAFP_00903 1.9e-144 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
DFEMHAFP_00904 6.9e-289 luxC 1.2.1.50 C Acyl-CoA reductase (LuxC)
DFEMHAFP_00905 4.8e-218 luxE 6.2.1.19 H long-chain-fatty-acid--luciferin-component ligase, acyl-protein synthase
DFEMHAFP_00906 1.3e-235 F Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_00907 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
DFEMHAFP_00908 2.6e-307 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
DFEMHAFP_00909 2e-74
DFEMHAFP_00910 7.6e-249 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
DFEMHAFP_00911 4.2e-158 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
DFEMHAFP_00912 1.8e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
DFEMHAFP_00913 4.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
DFEMHAFP_00914 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DFEMHAFP_00915 3.5e-157 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
DFEMHAFP_00916 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
DFEMHAFP_00917 3e-187 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
DFEMHAFP_00918 4.2e-74 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
DFEMHAFP_00919 5.2e-278 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
DFEMHAFP_00920 1.6e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
DFEMHAFP_00921 9.3e-155 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
DFEMHAFP_00922 6.6e-179 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
DFEMHAFP_00923 5.5e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DFEMHAFP_00924 2.9e-162 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
DFEMHAFP_00925 0.0 thiC 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DFEMHAFP_00926 1.1e-108 J Acetyltransferase (GNAT) domain
DFEMHAFP_00927 6.1e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DFEMHAFP_00928 4.7e-218 yxjG_1 E Psort location Cytoplasmic, score 8.87
DFEMHAFP_00929 6.1e-122 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
DFEMHAFP_00930 1.8e-50 sdpR K helix_turn_helix, Arsenical Resistance Operon Repressor
DFEMHAFP_00931 1.4e-139 S SdpI/YhfL protein family
DFEMHAFP_00932 2.1e-109 3.8.1.2 S Haloacid dehalogenase-like hydrolase
DFEMHAFP_00933 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DFEMHAFP_00934 2.5e-124 XK27_06785 V ABC transporter
DFEMHAFP_00937 4.3e-63
DFEMHAFP_00938 3.3e-96 M Peptidase family M23
DFEMHAFP_00939 0.0 fadD1 6.2.1.3 I AMP-binding enzyme
DFEMHAFP_00940 4e-268 G ABC transporter substrate-binding protein
DFEMHAFP_00941 5.3e-231 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
DFEMHAFP_00942 8.1e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
DFEMHAFP_00943 3e-107 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
DFEMHAFP_00944 9e-72 U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
DFEMHAFP_00945 2.6e-242 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DFEMHAFP_00946 3.6e-67 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
DFEMHAFP_00947 2.5e-143 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DFEMHAFP_00948 1.3e-117
DFEMHAFP_00950 1.3e-232 XK27_00240 K Fic/DOC family
DFEMHAFP_00951 9.2e-71 pdxH S Pfam:Pyridox_oxidase
DFEMHAFP_00952 2.7e-302 M domain protein
DFEMHAFP_00953 1.6e-82 3.4.22.70 M Sortase family
DFEMHAFP_00954 5.2e-65 3.4.22.70 M Sortase family
DFEMHAFP_00955 1.5e-163 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
DFEMHAFP_00956 5.7e-172 corA P CorA-like Mg2+ transporter protein
DFEMHAFP_00957 1.5e-142 ET Bacterial periplasmic substrate-binding proteins
DFEMHAFP_00958 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFEMHAFP_00959 1.3e-92 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
DFEMHAFP_00960 0.0 comE S Competence protein
DFEMHAFP_00961 6.5e-179 holA 2.7.7.7 L DNA polymerase III delta subunit
DFEMHAFP_00962 9.2e-94 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
DFEMHAFP_00963 1.3e-148 yeaZ 2.3.1.234 O Glycoprotease family
DFEMHAFP_00964 2.6e-103 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
DFEMHAFP_00965 2.6e-194 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DFEMHAFP_00967 2.6e-119 yoaP E YoaP-like
DFEMHAFP_00968 4.5e-185 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
DFEMHAFP_00969 5.3e-119 ykoE S ABC-type cobalt transport system, permease component
DFEMHAFP_00970 1.4e-71 K MerR family regulatory protein
DFEMHAFP_00971 4.6e-199 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
DFEMHAFP_00972 1.5e-143 4.1.1.44 S Carboxymuconolactone decarboxylase family
DFEMHAFP_00973 5.5e-222 yxjG_1 E Psort location Cytoplasmic, score 8.87
DFEMHAFP_00974 3.6e-76 S Psort location CytoplasmicMembrane, score
DFEMHAFP_00975 3.5e-183 cat P Cation efflux family
DFEMHAFP_00978 1.1e-110
DFEMHAFP_00979 3.7e-152
DFEMHAFP_00980 9.8e-146 mazG 3.6.1.66 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00981 9.4e-280 pepC 3.4.22.40 E Peptidase C1-like family
DFEMHAFP_00982 1.1e-175 S IMP dehydrogenase activity
DFEMHAFP_00983 1.3e-298 ybiT S ABC transporter
DFEMHAFP_00984 4.7e-111 pncA 2.7.11.1, 3.5.1.19 Q Isochorismatase family
DFEMHAFP_00985 2.8e-66 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DFEMHAFP_00987 2e-13
DFEMHAFP_00988 6.9e-274 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00989 1.8e-139 S Domain of unknown function (DUF4194)
DFEMHAFP_00990 1.2e-101 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00991 2.4e-147 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00992 5.6e-163 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_00993 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
DFEMHAFP_00994 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
DFEMHAFP_00995 7.1e-183 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
DFEMHAFP_00996 2.3e-170 rapZ S Displays ATPase and GTPase activities
DFEMHAFP_00997 1.3e-171 whiA K May be required for sporulation
DFEMHAFP_00998 1.9e-220 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
DFEMHAFP_00999 9.6e-149 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
DFEMHAFP_01000 2.4e-32 secG U Preprotein translocase SecG subunit
DFEMHAFP_01001 3.3e-163 S Sucrose-6F-phosphate phosphohydrolase
DFEMHAFP_01002 8e-301 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
DFEMHAFP_01003 1.2e-08 pnuC H Nicotinamide mononucleotide transporter
DFEMHAFP_01004 1.3e-28 pnuC H Nicotinamide mononucleotide transporter
DFEMHAFP_01005 2.5e-68 pnuC H Nicotinamide mononucleotide transporter
DFEMHAFP_01006 9.6e-49 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H ATPase kinase involved in NAD metabolism
DFEMHAFP_01007 4.2e-203 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DFEMHAFP_01008 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
DFEMHAFP_01009 1.1e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
DFEMHAFP_01010 2.4e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
DFEMHAFP_01011 5.1e-158 G Fructosamine kinase
DFEMHAFP_01012 6.9e-156 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
DFEMHAFP_01013 2.8e-156 S PAC2 family
DFEMHAFP_01020 1.2e-07
DFEMHAFP_01021 5.4e-36
DFEMHAFP_01022 4.7e-76 garA T Inner membrane component of T3SS, cytoplasmic domain
DFEMHAFP_01023 9.7e-112 K helix_turn_helix, mercury resistance
DFEMHAFP_01024 4.6e-61
DFEMHAFP_01025 3e-141 pgp 3.1.3.18 S HAD-hyrolase-like
DFEMHAFP_01026 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
DFEMHAFP_01027 0.0 helY L DEAD DEAH box helicase
DFEMHAFP_01028 2.1e-54
DFEMHAFP_01029 0.0 pafB K WYL domain
DFEMHAFP_01030 1.4e-264 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
DFEMHAFP_01032 1.1e-69
DFEMHAFP_01033 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
DFEMHAFP_01034 9.1e-144 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
DFEMHAFP_01035 1.5e-161 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
DFEMHAFP_01036 8.2e-34
DFEMHAFP_01037 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
DFEMHAFP_01038 1.9e-245
DFEMHAFP_01039 1.3e-160 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DFEMHAFP_01040 4.9e-221 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
DFEMHAFP_01041 1.8e-99 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DFEMHAFP_01042 1.8e-50 yajC U Preprotein translocase subunit
DFEMHAFP_01043 9.5e-200 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
DFEMHAFP_01044 1e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
DFEMHAFP_01045 1e-99 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DFEMHAFP_01046 5.2e-128 yebC K transcriptional regulatory protein
DFEMHAFP_01047 1e-111 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
DFEMHAFP_01048 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DFEMHAFP_01049 1.6e-141 S Bacterial protein of unknown function (DUF881)
DFEMHAFP_01050 4.2e-45 sbp S Protein of unknown function (DUF1290)
DFEMHAFP_01051 2.6e-172 S Bacterial protein of unknown function (DUF881)
DFEMHAFP_01052 5.1e-102 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFEMHAFP_01053 3.9e-156 hisG 2.4.2.17 F ATP phosphoribosyltransferase
DFEMHAFP_01054 1.9e-40 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
DFEMHAFP_01055 4.2e-97 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
DFEMHAFP_01056 4.6e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DFEMHAFP_01057 9.3e-161 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
DFEMHAFP_01058 0.0 trpB 4.1.1.48, 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DFEMHAFP_01059 2.1e-293 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DFEMHAFP_01060 2.9e-72 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DFEMHAFP_01061 3e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
DFEMHAFP_01062 3.6e-224 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
DFEMHAFP_01063 6.1e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
DFEMHAFP_01064 5.8e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
DFEMHAFP_01065 2.6e-135 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
DFEMHAFP_01067 5e-143 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DFEMHAFP_01068 1.9e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
DFEMHAFP_01069 1.1e-83 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFEMHAFP_01070 0.0 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
DFEMHAFP_01071 1.8e-121
DFEMHAFP_01073 5e-190 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DFEMHAFP_01074 1.8e-141 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DFEMHAFP_01075 3.2e-101
DFEMHAFP_01076 2.9e-243 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DFEMHAFP_01077 6.5e-251 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DFEMHAFP_01078 2.3e-284 thrC 4.2.3.1 E Threonine synthase N terminus
DFEMHAFP_01079 3e-232 EGP Major facilitator Superfamily
DFEMHAFP_01080 1e-107 3.1.3.27 E haloacid dehalogenase-like hydrolase
DFEMHAFP_01081 8.2e-173 G Fic/DOC family
DFEMHAFP_01082 2e-142
DFEMHAFP_01083 6.9e-164 IQ Enoyl-(Acyl carrier protein) reductase
DFEMHAFP_01084 1.2e-166 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DFEMHAFP_01085 7.4e-77 3.4.13.22 S Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DFEMHAFP_01087 5.4e-95 bcp 1.11.1.15 O Redoxin
DFEMHAFP_01088 5.2e-23 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_01089 1.6e-94 S Pyridoxamine 5'-phosphate oxidase
DFEMHAFP_01090 0.0 S Histidine phosphatase superfamily (branch 2)
DFEMHAFP_01091 1.6e-44 L transposition
DFEMHAFP_01092 2.5e-23 C Acetamidase/Formamidase family
DFEMHAFP_01093 1.7e-58 K helix_turn_helix gluconate operon transcriptional repressor
DFEMHAFP_01094 1.6e-174 V ATPases associated with a variety of cellular activities
DFEMHAFP_01095 2.6e-116 S ABC-2 family transporter protein
DFEMHAFP_01096 2.2e-122 S Haloacid dehalogenase-like hydrolase
DFEMHAFP_01097 1.2e-260 recN L May be involved in recombinational repair of damaged DNA
DFEMHAFP_01098 2e-177 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DFEMHAFP_01099 2.1e-266 trkB P Cation transport protein
DFEMHAFP_01100 3e-116 trkA P TrkA-N domain
DFEMHAFP_01101 2.9e-134 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
DFEMHAFP_01102 1.1e-192 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
DFEMHAFP_01103 1.5e-149 L Tetratricopeptide repeat
DFEMHAFP_01104 5e-251 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DFEMHAFP_01105 0.0 S Protein of unknown function (DUF975)
DFEMHAFP_01106 4.3e-136 S Putative ABC-transporter type IV
DFEMHAFP_01107 9.7e-94 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
DFEMHAFP_01108 2.9e-279 argH 4.3.2.1 E argininosuccinate lyase
DFEMHAFP_01109 3e-237 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
DFEMHAFP_01110 2.3e-82 argR K Regulates arginine biosynthesis genes
DFEMHAFP_01111 4.6e-185 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DFEMHAFP_01112 1e-240 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
DFEMHAFP_01113 2.8e-179 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
DFEMHAFP_01114 8.8e-215 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DFEMHAFP_01115 9.1e-206 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DFEMHAFP_01116 3.2e-98
DFEMHAFP_01117 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
DFEMHAFP_01118 2.4e-203 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DFEMHAFP_01119 3.3e-158 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFEMHAFP_01120 4.5e-97 yvdD 3.2.2.10 S Possible lysine decarboxylase
DFEMHAFP_01122 4.5e-18
DFEMHAFP_01124 1.5e-17 L HNH endonuclease
DFEMHAFP_01125 8.3e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
DFEMHAFP_01126 4e-42 V DNA modification
DFEMHAFP_01127 7.8e-282 glnA 6.3.1.2 E glutamine synthetase
DFEMHAFP_01128 6e-143 S Domain of unknown function (DUF4191)
DFEMHAFP_01129 8.4e-247 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DFEMHAFP_01130 3.6e-93 S Protein of unknown function (DUF3043)
DFEMHAFP_01131 2.7e-252 argE E Peptidase dimerisation domain
DFEMHAFP_01132 3.1e-145 cbiQ P Cobalt transport protein
DFEMHAFP_01133 1.5e-267 ykoD P ATPases associated with a variety of cellular activities
DFEMHAFP_01134 9.9e-85 ykoE S ABC-type cobalt transport system, permease component
DFEMHAFP_01135 2.1e-202 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
DFEMHAFP_01136 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DFEMHAFP_01137 0.0 S Tetratricopeptide repeat
DFEMHAFP_01138 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DFEMHAFP_01139 7.3e-308 2.8.2.22 S Arylsulfotransferase Ig-like domain
DFEMHAFP_01140 5e-145 bioM P ATPases associated with a variety of cellular activities
DFEMHAFP_01141 4e-220 E Aminotransferase class I and II
DFEMHAFP_01142 1.6e-140 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
DFEMHAFP_01143 6.3e-201 S Glycosyltransferase, group 2 family protein
DFEMHAFP_01144 1.8e-144 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DFEMHAFP_01145 2.4e-47 yhbY J CRS1_YhbY
DFEMHAFP_01146 0.0 ecfA GP ABC transporter, ATP-binding protein
DFEMHAFP_01147 3e-108 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
DFEMHAFP_01148 0.0 snf 2.7.11.1 KL Psort location Cytoplasmic, score 8.87
DFEMHAFP_01149 1.3e-113 kcsA U Ion channel
DFEMHAFP_01150 2.2e-187 ghrA EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
DFEMHAFP_01151 2.5e-83 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
DFEMHAFP_01152 1.7e-122 3.2.1.8 S alpha beta
DFEMHAFP_01154 2.2e-51 S Protein of unknown function DUF262
DFEMHAFP_01155 9.3e-196 S Protein of unknown function DUF262
DFEMHAFP_01156 1.8e-142 S Protein of unknown function DUF262
DFEMHAFP_01158 3.2e-190
DFEMHAFP_01159 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
DFEMHAFP_01160 0.0 thiN 2.7.6.2 H PglZ domain
DFEMHAFP_01161 2.9e-258 lexA 3.6.4.12 K Putative DNA-binding domain
DFEMHAFP_01162 8.4e-75 S Domain of unknown function (DUF4263)
DFEMHAFP_01163 0.0 LV DNA restriction-modification system
DFEMHAFP_01164 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
DFEMHAFP_01165 9.6e-124 S Domain of unknown function (DUF1788)
DFEMHAFP_01166 3.9e-114 S Putative inner membrane protein (DUF1819)
DFEMHAFP_01168 1.1e-127 E Psort location Cytoplasmic, score 8.87
DFEMHAFP_01169 5e-131 yebE S DUF218 domain
DFEMHAFP_01170 7.7e-231 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
DFEMHAFP_01171 3.4e-236 rnd 3.1.13.5 J 3'-5' exonuclease
DFEMHAFP_01172 9.9e-80 S Protein of unknown function (DUF3000)
DFEMHAFP_01173 7.4e-166 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DFEMHAFP_01174 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
DFEMHAFP_01175 4.5e-31
DFEMHAFP_01176 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DFEMHAFP_01177 4.1e-225 S Peptidase dimerisation domain
DFEMHAFP_01178 3.7e-156 S Sucrose-6F-phosphate phosphohydrolase
DFEMHAFP_01179 2.1e-146 metQ P NLPA lipoprotein
DFEMHAFP_01180 5.5e-147 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DFEMHAFP_01181 5.4e-108 metI P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01182 1.4e-74
DFEMHAFP_01184 2.4e-101 V Abi-like protein
DFEMHAFP_01185 7.3e-56 L Helix-turn-helix domain
DFEMHAFP_01187 0.0 S LPXTG-motif cell wall anchor domain protein
DFEMHAFP_01188 2.3e-246 dinF V MatE
DFEMHAFP_01189 1.2e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DFEMHAFP_01190 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DFEMHAFP_01191 1.3e-84 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
DFEMHAFP_01192 1e-47 S Domain of unknown function (DUF4193)
DFEMHAFP_01193 7e-147 S Protein of unknown function (DUF3071)
DFEMHAFP_01194 1.2e-230 S Type I phosphodiesterase / nucleotide pyrophosphatase
DFEMHAFP_01195 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DFEMHAFP_01196 0.0 lhr L DEAD DEAH box helicase
DFEMHAFP_01197 2.2e-31 yozG K Cro/C1-type HTH DNA-binding domain
DFEMHAFP_01198 2.4e-79 S Protein of unknown function (DUF2975)
DFEMHAFP_01199 2.4e-240 T PhoQ Sensor
DFEMHAFP_01200 3.4e-222 G Major Facilitator Superfamily
DFEMHAFP_01201 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
DFEMHAFP_01202 9.7e-173 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
DFEMHAFP_01203 7.3e-118
DFEMHAFP_01204 4.5e-197 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
DFEMHAFP_01205 0.0 pknL 2.7.11.1 KLT PASTA
DFEMHAFP_01206 1.9e-132 plsC2 2.3.1.51 I Phosphate acyltransferases
DFEMHAFP_01207 1.3e-97
DFEMHAFP_01208 3.4e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DFEMHAFP_01209 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
DFEMHAFP_01210 3.3e-118 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DFEMHAFP_01211 1.3e-122 recX S Modulates RecA activity
DFEMHAFP_01212 5.4e-212 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DFEMHAFP_01213 4.3e-46 S Protein of unknown function (DUF3046)
DFEMHAFP_01214 1.6e-80 K Helix-turn-helix XRE-family like proteins
DFEMHAFP_01215 6.1e-97 cinA 3.5.1.42 S Belongs to the CinA family
DFEMHAFP_01216 4.1e-124 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DFEMHAFP_01217 0.0 ftsK D FtsK SpoIIIE family protein
DFEMHAFP_01218 1.3e-193 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DFEMHAFP_01219 1e-281 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DFEMHAFP_01220 1.1e-155 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
DFEMHAFP_01221 6.2e-177 ydeD EG EamA-like transporter family
DFEMHAFP_01222 1.7e-127 ybhL S Belongs to the BI1 family
DFEMHAFP_01223 1.5e-59 S Domain of unknown function (DUF5067)
DFEMHAFP_01224 5.1e-243 T Histidine kinase
DFEMHAFP_01225 1.8e-127 K helix_turn_helix, Lux Regulon
DFEMHAFP_01226 0.0 S Protein of unknown function DUF262
DFEMHAFP_01227 9e-116 K helix_turn_helix, Lux Regulon
DFEMHAFP_01228 1.2e-244 T Histidine kinase
DFEMHAFP_01229 4.4e-191 V ATPases associated with a variety of cellular activities
DFEMHAFP_01230 7.7e-225 V ABC-2 family transporter protein
DFEMHAFP_01231 1.1e-229 V ABC-2 family transporter protein
DFEMHAFP_01232 2.2e-209 rhaR1 K helix_turn_helix, arabinose operon control protein
DFEMHAFP_01233 4.7e-109 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
DFEMHAFP_01234 9.9e-250 VP1224 V Psort location CytoplasmicMembrane, score 9.99
DFEMHAFP_01235 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DFEMHAFP_01236 0.0 ctpE P E1-E2 ATPase
DFEMHAFP_01237 2e-74
DFEMHAFP_01238 1.4e-242 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DFEMHAFP_01239 2.4e-133 S Protein of unknown function (DUF3159)
DFEMHAFP_01240 2.8e-151 S Protein of unknown function (DUF3710)
DFEMHAFP_01241 1.4e-172 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
DFEMHAFP_01242 0.0 dppD EP Oligopeptide/dipeptide transporter, C-terminal region
DFEMHAFP_01243 4.1e-170 dppC EP N-terminal TM domain of oligopeptide transport permease C
DFEMHAFP_01244 1.6e-155 dppB EP Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01245 1.2e-299 E ABC transporter, substrate-binding protein, family 5
DFEMHAFP_01246 1.6e-171 xerC D Belongs to the 'phage' integrase family. XerC subfamily
DFEMHAFP_01247 5.2e-08
DFEMHAFP_01248 2.8e-34
DFEMHAFP_01249 8.9e-195 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
DFEMHAFP_01250 1.3e-190 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
DFEMHAFP_01251 1.2e-103
DFEMHAFP_01252 0.0 typA T Elongation factor G C-terminus
DFEMHAFP_01253 3.1e-248 naiP U Sugar (and other) transporter
DFEMHAFP_01254 2.1e-151 nrtR 3.6.1.55 F NUDIX hydrolase
DFEMHAFP_01255 6.8e-153 soj D CobQ CobB MinD ParA nucleotide binding domain protein
DFEMHAFP_01256 2e-177 xerD D recombinase XerD
DFEMHAFP_01257 9.6e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DFEMHAFP_01258 2.1e-25 rpmI J Ribosomal protein L35
DFEMHAFP_01259 1.6e-103 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DFEMHAFP_01260 4.9e-110 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
DFEMHAFP_01261 1.8e-198 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
DFEMHAFP_01262 2.1e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DFEMHAFP_01263 7.9e-172 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DFEMHAFP_01264 1.3e-187 galM 5.1.3.3 G Aldose 1-epimerase
DFEMHAFP_01265 5.9e-36
DFEMHAFP_01266 5.7e-98 sigH K Belongs to the sigma-70 factor family. ECF subfamily
DFEMHAFP_01267 3.9e-279 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DFEMHAFP_01268 5e-187 V Acetyltransferase (GNAT) domain
DFEMHAFP_01269 5.3e-287 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
DFEMHAFP_01270 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
DFEMHAFP_01271 4e-95 3.6.1.55 F NUDIX domain
DFEMHAFP_01272 0.0 P Belongs to the ABC transporter superfamily
DFEMHAFP_01273 4.7e-192 dppC EP Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01274 1.7e-188 dppB EP Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01275 2.3e-306 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
DFEMHAFP_01276 1.7e-218 GK ROK family
DFEMHAFP_01277 4.9e-165 2.7.1.4 G pfkB family carbohydrate kinase
DFEMHAFP_01278 3.5e-220 S Metal-independent alpha-mannosidase (GH125)
DFEMHAFP_01279 3.5e-27
DFEMHAFP_01280 8.4e-248 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
DFEMHAFP_01281 5e-140 ftsQ 6.3.2.4 D Cell division protein FtsQ
DFEMHAFP_01282 1e-271 murC 6.3.2.8 M Belongs to the MurCDEF family
DFEMHAFP_01283 6.3e-216 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DFEMHAFP_01284 1.1e-202 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
DFEMHAFP_01285 2.1e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DFEMHAFP_01286 8.8e-193 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DFEMHAFP_01287 9e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
DFEMHAFP_01288 6.3e-149 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DFEMHAFP_01289 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
DFEMHAFP_01290 1.8e-62 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DFEMHAFP_01291 1.3e-190 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
DFEMHAFP_01292 2.7e-91 mraZ K Belongs to the MraZ family
DFEMHAFP_01293 0.0 L DNA helicase
DFEMHAFP_01294 1.1e-217 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
DFEMHAFP_01295 2.9e-84 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DFEMHAFP_01296 1e-53 M Lysin motif
DFEMHAFP_01297 2.2e-131 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DFEMHAFP_01298 1.3e-149 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DFEMHAFP_01299 2.3e-176 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
DFEMHAFP_01300 4.9e-271 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DFEMHAFP_01301 1.1e-112 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
DFEMHAFP_01302 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
DFEMHAFP_01303 1.8e-190
DFEMHAFP_01304 2.3e-185 V N-Acetylmuramoyl-L-alanine amidase
DFEMHAFP_01305 8.4e-80
DFEMHAFP_01306 2.7e-56 T helix_turn_helix, Lux Regulon
DFEMHAFP_01307 1.9e-28 2.7.13.3 T Histidine kinase
DFEMHAFP_01308 6.5e-119 ytrE V ATPases associated with a variety of cellular activities
DFEMHAFP_01309 4e-218 EGP Major facilitator Superfamily
DFEMHAFP_01310 1.1e-151 M Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
DFEMHAFP_01311 3.1e-217 S Domain of unknown function (DUF5067)
DFEMHAFP_01312 2e-263 glnA2 6.3.1.2 E glutamine synthetase
DFEMHAFP_01313 1.4e-130 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
DFEMHAFP_01314 6.3e-122 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DFEMHAFP_01315 1.5e-122
DFEMHAFP_01316 1.5e-109 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
DFEMHAFP_01317 2.5e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DFEMHAFP_01318 2.4e-259 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DFEMHAFP_01319 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
DFEMHAFP_01320 4.9e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
DFEMHAFP_01321 4.3e-87 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DFEMHAFP_01322 4.5e-31 3.1.21.3 V DivIVA protein
DFEMHAFP_01323 1.2e-40 yggT S YGGT family
DFEMHAFP_01324 8.9e-81 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
DFEMHAFP_01325 5.6e-220 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DFEMHAFP_01326 3.2e-244 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DFEMHAFP_01327 8.2e-295 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
DFEMHAFP_01328 1e-105 S Pilus assembly protein, PilO
DFEMHAFP_01329 1.8e-165 pilN NU PFAM Fimbrial assembly family protein
DFEMHAFP_01330 3e-190 pilM NU Type IV pilus assembly protein PilM;
DFEMHAFP_01331 5.3e-150 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
DFEMHAFP_01332 0.0
DFEMHAFP_01333 2.1e-230 pilC U Type II secretion system (T2SS), protein F
DFEMHAFP_01334 1.8e-40 pilA NU Prokaryotic N-terminal methylation motif
DFEMHAFP_01335 1.6e-104 S Prokaryotic N-terminal methylation motif
DFEMHAFP_01336 4.9e-137 ppdC NU Prokaryotic N-terminal methylation motif
DFEMHAFP_01337 0.0 pulE NU Type II/IV secretion system protein
DFEMHAFP_01338 0.0 pilT NU Type II/IV secretion system protein
DFEMHAFP_01339 0.0
DFEMHAFP_01340 2.2e-154 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
DFEMHAFP_01341 1.1e-133 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
DFEMHAFP_01342 2.9e-151 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
DFEMHAFP_01343 3e-60 S Thiamine-binding protein
DFEMHAFP_01344 6.4e-193 K helix_turn _helix lactose operon repressor
DFEMHAFP_01345 2.8e-241 lacY P LacY proton/sugar symporter
DFEMHAFP_01346 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DFEMHAFP_01347 1.4e-142 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01348 5.3e-206 P NMT1/THI5 like
DFEMHAFP_01349 4.6e-217 iunH1 3.2.2.1 F nucleoside hydrolase
DFEMHAFP_01350 4e-155 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DFEMHAFP_01351 7.3e-135 recO L Involved in DNA repair and RecF pathway recombination
DFEMHAFP_01352 0.0 I acetylesterase activity
DFEMHAFP_01353 3.3e-225 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DFEMHAFP_01354 6.3e-205 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
DFEMHAFP_01355 1.8e-239 2.7.11.1 NU Tfp pilus assembly protein FimV
DFEMHAFP_01357 6.5e-75 S Protein of unknown function (DUF3052)
DFEMHAFP_01358 1e-154 lon T Belongs to the peptidase S16 family
DFEMHAFP_01359 1.6e-283 S Zincin-like metallopeptidase
DFEMHAFP_01360 1.6e-282 uvrD2 3.6.4.12 L DNA helicase
DFEMHAFP_01361 3.6e-269 mphA S Aminoglycoside phosphotransferase
DFEMHAFP_01362 3.6e-32 S Protein of unknown function (DUF3107)
DFEMHAFP_01363 1.1e-172 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
DFEMHAFP_01364 2.1e-117 S Vitamin K epoxide reductase
DFEMHAFP_01365 7.8e-171 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
DFEMHAFP_01366 2.2e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
DFEMHAFP_01367 1.2e-13 S lipid catabolic process
DFEMHAFP_01368 1.7e-301 E ABC transporter, substrate-binding protein, family 5
DFEMHAFP_01369 4.9e-176 iaaA 3.4.19.5, 3.5.1.1 E Asparaginase
DFEMHAFP_01370 1.5e-160 S Patatin-like phospholipase
DFEMHAFP_01371 3.9e-187 K LysR substrate binding domain protein
DFEMHAFP_01372 1.4e-239 patB 4.4.1.8 E Aminotransferase, class I II
DFEMHAFP_01373 7.4e-126 S Phospholipase/Carboxylesterase
DFEMHAFP_01374 6.6e-47 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DFEMHAFP_01375 1.5e-197 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DFEMHAFP_01376 1.7e-130 cas4 3.1.12.1 L Domain of unknown function DUF83
DFEMHAFP_01377 4.5e-152 csd2 L CRISPR-associated protein Cas7
DFEMHAFP_01378 0.0 csd1 3.5.1.28 M CRISPR-associated protein (Cas_Csd1)
DFEMHAFP_01379 1.2e-137 cas5d S CRISPR-associated protein (Cas_Cas5)
DFEMHAFP_01380 0.0 cas3 L DEAD-like helicases superfamily
DFEMHAFP_01381 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DFEMHAFP_01382 1e-257 lacS G Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_01383 2.8e-185 lacR K Transcriptional regulator, LacI family
DFEMHAFP_01384 0.0 V ABC transporter transmembrane region
DFEMHAFP_01385 0.0 V ABC transporter, ATP-binding protein
DFEMHAFP_01386 1.3e-96 K MarR family
DFEMHAFP_01387 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DFEMHAFP_01388 1.5e-106 K Bacterial regulatory proteins, tetR family
DFEMHAFP_01389 9.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
DFEMHAFP_01390 2.4e-181 G Transporter major facilitator family protein
DFEMHAFP_01391 0.0 3.2.1.40 E Bacterial alpha-L-rhamnosidase C-terminal domain
DFEMHAFP_01392 6.3e-214 EGP Major facilitator Superfamily
DFEMHAFP_01393 6.8e-118 K Periplasmic binding protein domain
DFEMHAFP_01394 4.5e-14 K helix_turn_helix, mercury resistance
DFEMHAFP_01395 8.8e-220 lmrB U Major Facilitator Superfamily
DFEMHAFP_01396 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
DFEMHAFP_01397 4.3e-107 K Bacterial regulatory proteins, tetR family
DFEMHAFP_01398 1.1e-239 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DFEMHAFP_01399 0.0 3.2.1.37 GH43 G Glycosyl hydrolases family 43
DFEMHAFP_01400 6e-251 3.2.1.58 G Belongs to the glycosyl hydrolase 5 (cellulase A) family
DFEMHAFP_01401 0.0 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
DFEMHAFP_01402 1.9e-223 blt G MFS/sugar transport protein
DFEMHAFP_01403 8e-96 K transcriptional regulator
DFEMHAFP_01404 9.5e-274 srfJ1 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
DFEMHAFP_01405 2.8e-241 G Transporter major facilitator family protein
DFEMHAFP_01406 6.7e-113 K Bacterial regulatory proteins, tetR family
DFEMHAFP_01407 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
DFEMHAFP_01408 4.2e-115 K Bacterial regulatory proteins, tetR family
DFEMHAFP_01409 1.6e-254 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
DFEMHAFP_01410 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
DFEMHAFP_01411 1.1e-155 hgdC I BadF/BadG/BcrA/BcrD ATPase family
DFEMHAFP_01412 1.6e-139 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DFEMHAFP_01413 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
DFEMHAFP_01414 1.5e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFEMHAFP_01415 1.5e-40 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
DFEMHAFP_01417 2.2e-196 S Endonuclease/Exonuclease/phosphatase family
DFEMHAFP_01418 8.9e-30 L COG0675 Transposase and inactivated derivatives
DFEMHAFP_01419 3.7e-36 VY92_01845 L Transposase IS200 like
DFEMHAFP_01421 1e-99 tmp1 S Domain of unknown function (DUF4391)
DFEMHAFP_01422 3e-168 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
DFEMHAFP_01423 1.1e-233 aspB E Aminotransferase class-V
DFEMHAFP_01424 1.9e-70 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
DFEMHAFP_01425 1.8e-187 afr_2 S Oxidoreductase family, NAD-binding Rossmann fold
DFEMHAFP_01426 0.0 helD 3.6.4.12 L Psort location Cytoplasmic, score 8.87
DFEMHAFP_01427 6.4e-201 V Domain of unknown function (DUF3427)
DFEMHAFP_01428 1.5e-76
DFEMHAFP_01429 7.5e-71 S Bacterial PH domain
DFEMHAFP_01430 3.8e-243 S zinc finger
DFEMHAFP_01432 0.0 3.2.1.24 GH38 G Alpha mannosidase, middle domain
DFEMHAFP_01433 1.5e-40 3.2.1.24 GH38 G Alpha mannosidase, middle domain
DFEMHAFP_01434 3.8e-15 S COG NOG14600 non supervised orthologous group
DFEMHAFP_01436 2.3e-10
DFEMHAFP_01437 1.3e-282 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
DFEMHAFP_01438 4.3e-110 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
DFEMHAFP_01439 1e-254 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DFEMHAFP_01440 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
DFEMHAFP_01441 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DFEMHAFP_01442 4.7e-174 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DFEMHAFP_01443 0.0 pacS 3.6.3.54 P E1-E2 ATPase
DFEMHAFP_01444 1.1e-38 csoR S Metal-sensitive transcriptional repressor
DFEMHAFP_01445 4.1e-133 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
DFEMHAFP_01446 1.7e-246 G Major Facilitator Superfamily
DFEMHAFP_01447 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
DFEMHAFP_01448 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
DFEMHAFP_01449 5.2e-262 KLT Protein tyrosine kinase
DFEMHAFP_01450 0.0 S Fibronectin type 3 domain
DFEMHAFP_01451 7.7e-226 S ATPase family associated with various cellular activities (AAA)
DFEMHAFP_01452 8.3e-221 S Protein of unknown function DUF58
DFEMHAFP_01453 0.0 E Transglutaminase-like superfamily
DFEMHAFP_01454 1.3e-162 3.1.3.16 T Sigma factor PP2C-like phosphatases
DFEMHAFP_01455 1.3e-104 B Belongs to the OprB family
DFEMHAFP_01456 1.1e-101 T Forkhead associated domain
DFEMHAFP_01457 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFEMHAFP_01458 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DFEMHAFP_01459 6.8e-100
DFEMHAFP_01460 3.5e-182 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
DFEMHAFP_01461 3.3e-126 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
DFEMHAFP_01462 1.5e-253 S UPF0210 protein
DFEMHAFP_01463 7.9e-42 gcvR T Belongs to the UPF0237 family
DFEMHAFP_01464 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
DFEMHAFP_01465 2.5e-195 K helix_turn _helix lactose operon repressor
DFEMHAFP_01466 1.3e-122 S Protein of unknown function, DUF624
DFEMHAFP_01467 2.8e-171 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01468 8.4e-179 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01469 0.0 G Bacterial extracellular solute-binding protein
DFEMHAFP_01470 1.1e-231 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
DFEMHAFP_01471 1.1e-250 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
DFEMHAFP_01472 3.4e-141 glpR K DeoR C terminal sensor domain
DFEMHAFP_01473 8.8e-228 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
DFEMHAFP_01474 8.8e-220 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
DFEMHAFP_01475 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
DFEMHAFP_01476 2.3e-133 glxR K helix_turn_helix, cAMP Regulatory protein
DFEMHAFP_01477 2e-216 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
DFEMHAFP_01478 3.7e-86 J TM2 domain
DFEMHAFP_01479 2.2e-193 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
DFEMHAFP_01480 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
DFEMHAFP_01481 1.5e-236 S Uncharacterized conserved protein (DUF2183)
DFEMHAFP_01482 1e-69 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
DFEMHAFP_01483 8.7e-209 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
DFEMHAFP_01484 2.2e-159 mhpC I Alpha/beta hydrolase family
DFEMHAFP_01485 3.5e-114 F Domain of unknown function (DUF4916)
DFEMHAFP_01486 6e-61 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
DFEMHAFP_01487 2.1e-169 S G5
DFEMHAFP_01488 7.8e-88
DFEMHAFP_01489 1.9e-71
DFEMHAFP_01490 1.6e-28 K Cro/C1-type HTH DNA-binding domain
DFEMHAFP_01491 2.4e-76
DFEMHAFP_01492 4.4e-97 3.1.3.48 T Low molecular weight phosphatase family
DFEMHAFP_01493 5.5e-246 wcoI DM Psort location CytoplasmicMembrane, score
DFEMHAFP_01494 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
DFEMHAFP_01495 6.5e-148 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01496 3.8e-162 P Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01497 8.6e-270 G Bacterial extracellular solute-binding protein
DFEMHAFP_01498 1.4e-184 K Psort location Cytoplasmic, score
DFEMHAFP_01499 1.2e-16 yccF S Inner membrane component domain
DFEMHAFP_01500 8.5e-253 S Psort location CytoplasmicMembrane, score 9.99
DFEMHAFP_01501 2.4e-73 doc S Fic/DOC family
DFEMHAFP_01502 6.5e-90 gepA S Protein of unknown function (DUF4065)
DFEMHAFP_01503 7.4e-18
DFEMHAFP_01504 1.1e-50 S Bacteriophage abortive infection AbiH
DFEMHAFP_01505 0.0 C Domain of unknown function (DUF4365)
DFEMHAFP_01506 1.5e-122 K SIR2-like domain
DFEMHAFP_01507 4.7e-168 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DFEMHAFP_01508 2.1e-255 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
DFEMHAFP_01509 3.8e-187 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DFEMHAFP_01510 5.5e-113 wbiB 5.1.3.25 GM 3-beta hydroxysteroid dehydrogenase/isomerase family
DFEMHAFP_01511 1.4e-27 GM Bacterial transferase hexapeptide (six repeats)
DFEMHAFP_01512 1.6e-164 MA20_43635 M Capsular polysaccharide synthesis protein
DFEMHAFP_01513 8.8e-187 M Glycosyl transferase 4-like domain
DFEMHAFP_01514 1.2e-120 cps4J S Polysaccharide biosynthesis protein
DFEMHAFP_01515 1e-32 GT8 S Protein conserved in bacteria
DFEMHAFP_01516 1.5e-13 S Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_01517 2.3e-50 2.3.1.30 E Hexapeptide repeat of succinyl-transferase
DFEMHAFP_01518 9.4e-110 1.1.1.339 GM GDP-mannose 4,6 dehydratase
DFEMHAFP_01519 3.2e-62 M Glycosyl transferases group 1
DFEMHAFP_01520 2.6e-201 1.1.1.22 M UDP binding domain
DFEMHAFP_01521 1.1e-160 lspL 5.1.3.6 M epimerase dehydratase
DFEMHAFP_01522 2.9e-178 M Domain of unknown function (DUF1972)
DFEMHAFP_01523 9.6e-49 V Abi-like protein
DFEMHAFP_01524 3e-179
DFEMHAFP_01525 7.1e-295 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
DFEMHAFP_01526 2e-301 2.1.1.107, 2.1.1.294, 2.7.1.181, 2.7.11.1 H Protein of unknown function (DUF4012)
DFEMHAFP_01527 2.7e-188 S Endonuclease/Exonuclease/phosphatase family
DFEMHAFP_01528 9.6e-47
DFEMHAFP_01529 5.2e-284 EGP Major facilitator Superfamily
DFEMHAFP_01530 1.2e-244 T Diguanylate cyclase (GGDEF) domain protein
DFEMHAFP_01531 2.1e-116 L Protein of unknown function (DUF1524)
DFEMHAFP_01532 9.3e-166 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
DFEMHAFP_01533 9.9e-239 mntH P H( )-stimulated, divalent metal cation uptake system
DFEMHAFP_01534 8.9e-198 K helix_turn _helix lactose operon repressor
DFEMHAFP_01535 0.0 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_01536 4.5e-167 G ABC transporter permease
DFEMHAFP_01537 1.2e-153 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01538 9.1e-240 G Bacterial extracellular solute-binding protein
DFEMHAFP_01539 2.1e-129 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
DFEMHAFP_01540 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
DFEMHAFP_01541 0.0 cydD V ABC transporter transmembrane region
DFEMHAFP_01542 0.0 fadD 6.2.1.3 I AMP-binding enzyme
DFEMHAFP_01543 6.3e-298 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
DFEMHAFP_01544 1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
DFEMHAFP_01545 0.0 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
DFEMHAFP_01546 2.1e-210 K helix_turn _helix lactose operon repressor
DFEMHAFP_01547 2.4e-286 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
DFEMHAFP_01548 1.4e-189 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
DFEMHAFP_01549 1.6e-241 hom 1.1.1.3 E Homoserine dehydrogenase
DFEMHAFP_01550 4.5e-299 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
DFEMHAFP_01551 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
DFEMHAFP_01552 1.7e-271 mmuP E amino acid
DFEMHAFP_01553 7e-60 psp1 3.5.99.10 J Endoribonuclease L-PSP
DFEMHAFP_01555 4.7e-122 cyaA 4.6.1.1 S CYTH
DFEMHAFP_01556 1.9e-170 trxA2 O Tetratricopeptide repeat
DFEMHAFP_01557 1e-179
DFEMHAFP_01558 4.8e-195
DFEMHAFP_01559 6.8e-149 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
DFEMHAFP_01560 2.3e-122 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
DFEMHAFP_01561 2.3e-44 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
DFEMHAFP_01562 5.6e-283 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DFEMHAFP_01563 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DFEMHAFP_01564 3.8e-309 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DFEMHAFP_01565 5e-148 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFEMHAFP_01566 4.4e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DFEMHAFP_01567 8.9e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DFEMHAFP_01568 2e-146 atpB C it plays a direct role in the translocation of protons across the membrane
DFEMHAFP_01569 5.4e-208 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DFEMHAFP_01571 5e-273 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
DFEMHAFP_01572 5.7e-192 yfdV S Membrane transport protein
DFEMHAFP_01573 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
DFEMHAFP_01574 7.1e-175 M LPXTG-motif cell wall anchor domain protein
DFEMHAFP_01575 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
DFEMHAFP_01576 3.4e-91 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DFEMHAFP_01577 9.4e-98 mntP P Probably functions as a manganese efflux pump
DFEMHAFP_01578 4.9e-134
DFEMHAFP_01579 4.9e-134 KT Transcriptional regulatory protein, C terminal
DFEMHAFP_01580 3.2e-123 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DFEMHAFP_01581 7.8e-288 E Bacterial extracellular solute-binding proteins, family 5 Middle
DFEMHAFP_01582 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
DFEMHAFP_01583 0.0 S domain protein
DFEMHAFP_01584 1e-69 tyrA 5.4.99.5 E Chorismate mutase type II
DFEMHAFP_01585 1.3e-79 K helix_turn_helix ASNC type
DFEMHAFP_01586 1.9e-247 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DFEMHAFP_01587 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
DFEMHAFP_01588 2.1e-51 S Protein of unknown function (DUF2469)
DFEMHAFP_01589 2e-205 2.3.1.57 J Acetyltransferase (GNAT) domain
DFEMHAFP_01590 2.5e-283 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFEMHAFP_01591 2.5e-286 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
DFEMHAFP_01592 1.3e-46 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DFEMHAFP_01593 6.2e-134 K Psort location Cytoplasmic, score
DFEMHAFP_01594 2e-132 spoU 2.1.1.185 J RNA methyltransferase TrmH family
DFEMHAFP_01595 2.7e-104 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DFEMHAFP_01596 3.7e-169 rmuC S RmuC family
DFEMHAFP_01597 9.6e-134 3.6.3.3, 3.6.3.5, 3.6.3.54 P Heavy metal translocating P-type atpase
DFEMHAFP_01598 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
DFEMHAFP_01599 1.4e-164 fahA Q Fumarylacetoacetate (FAA) hydrolase family
DFEMHAFP_01600 6.5e-148 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DFEMHAFP_01601 1.2e-79
DFEMHAFP_01602 2.8e-210 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
DFEMHAFP_01603 2.9e-53 M Protein of unknown function (DUF3152)
DFEMHAFP_01604 4.2e-09 M Protein of unknown function (DUF3152)
DFEMHAFP_01605 9.2e-130 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
DFEMHAFP_01607 1.7e-70 rplI J Binds to the 23S rRNA
DFEMHAFP_01608 3.5e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DFEMHAFP_01609 1.7e-69 ssb1 L Single-stranded DNA-binding protein
DFEMHAFP_01610 2.5e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
DFEMHAFP_01611 8.2e-185 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DFEMHAFP_01612 5.7e-175 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DFEMHAFP_01613 1.1e-259 EGP Major Facilitator Superfamily
DFEMHAFP_01614 3.3e-167 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
DFEMHAFP_01615 1.1e-197 K helix_turn _helix lactose operon repressor
DFEMHAFP_01616 1.2e-61
DFEMHAFP_01617 4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
DFEMHAFP_01618 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
DFEMHAFP_01619 1.3e-208 1.1.1.22 M UDP binding domain
DFEMHAFP_01620 0.0 wbbM M Glycosyl transferase family 8
DFEMHAFP_01621 1.9e-128 rgpC U Transport permease protein
DFEMHAFP_01622 1.7e-168 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
DFEMHAFP_01623 2.1e-57 wbbM M Glycosyl transferase family 8
DFEMHAFP_01624 0.0 wbbM M Glycosyl transferase family 8
DFEMHAFP_01625 4.4e-13
DFEMHAFP_01626 1.2e-206
DFEMHAFP_01627 1.1e-115 I Acyltransferase family
DFEMHAFP_01628 4.8e-155 rfbJ M Glycosyl transferase family 2
DFEMHAFP_01629 3.8e-259 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DFEMHAFP_01630 1.4e-27 lytC 2.1.1.197, 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
DFEMHAFP_01631 1.2e-258 S AAA domain
DFEMHAFP_01632 1.6e-70
DFEMHAFP_01633 5.9e-297 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
DFEMHAFP_01634 5.6e-59
DFEMHAFP_01635 2.7e-80
DFEMHAFP_01636 5e-173
DFEMHAFP_01637 6.5e-137 L HNH endonuclease
DFEMHAFP_01639 5.5e-172 S Domain of unknown function (DUF4928)
DFEMHAFP_01640 3.3e-230 dcm 2.1.1.37 L Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
DFEMHAFP_01642 4.4e-176 T AAA domain
DFEMHAFP_01643 1.3e-183 T regulation of circadian rhythm
DFEMHAFP_01644 1.1e-26
DFEMHAFP_01645 4.4e-78 L Phage integrase, N-terminal SAM-like domain
DFEMHAFP_01646 2.9e-64 L Phage integrase, N-terminal SAM-like domain
DFEMHAFP_01648 1.1e-156 EGP Major facilitator Superfamily
DFEMHAFP_01649 8.3e-31 yuxJ EGP Major facilitator Superfamily
DFEMHAFP_01651 0.0 S Psort location CytoplasmicMembrane, score 9.99
DFEMHAFP_01652 1.2e-241 V ABC transporter permease
DFEMHAFP_01653 1.7e-157 V ABC transporter
DFEMHAFP_01654 5.1e-150 T HD domain
DFEMHAFP_01655 1e-167 S Glutamine amidotransferase domain
DFEMHAFP_01656 0.0 kup P Transport of potassium into the cell
DFEMHAFP_01657 8.5e-184 tatD L TatD related DNase
DFEMHAFP_01658 0.0 G Alpha-L-arabinofuranosidase C-terminus
DFEMHAFP_01659 6.6e-233 G Alpha galactosidase A
DFEMHAFP_01660 9.2e-223 K helix_turn _helix lactose operon repressor
DFEMHAFP_01661 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_01662 8e-126
DFEMHAFP_01663 0.0 yknV V ABC transporter
DFEMHAFP_01664 0.0 mdlA2 V ABC transporter
DFEMHAFP_01665 1.1e-214 lipA I Hydrolase, alpha beta domain protein
DFEMHAFP_01666 1.3e-66 S Psort location Cytoplasmic, score 8.87
DFEMHAFP_01667 2.5e-155 I alpha/beta hydrolase fold
DFEMHAFP_01668 3.2e-233 M Protein of unknown function (DUF2961)
DFEMHAFP_01669 0.0 M probably involved in cell wall
DFEMHAFP_01670 5.5e-250 3.2.1.14 GH18 S Carbohydrate binding domain
DFEMHAFP_01671 0.0 T Diguanylate cyclase, GGDEF domain
DFEMHAFP_01672 2.9e-64 T Diguanylate cyclase, GGDEF domain
DFEMHAFP_01673 4.3e-186 lacR K Transcriptional regulator, LacI family
DFEMHAFP_01674 7.5e-223 nagA 3.5.1.25 G Amidohydrolase family
DFEMHAFP_01675 1.2e-149 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
DFEMHAFP_01676 0.0 G Glycosyl hydrolase family 20, domain 2
DFEMHAFP_01677 6.6e-173 2.7.1.2 GK ROK family
DFEMHAFP_01678 1.4e-57 G ABC transporter permease
DFEMHAFP_01679 8.3e-134 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01680 4.4e-162 G ABC transporter permease
DFEMHAFP_01681 5.8e-208 GK ROK family
DFEMHAFP_01682 1.6e-259 lacS G Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_01683 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_01684 4.1e-135 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)
DFEMHAFP_01686 0.0 cbgA_1 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
DFEMHAFP_01687 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DFEMHAFP_01688 6.6e-107
DFEMHAFP_01689 7.1e-73
DFEMHAFP_01690 6.1e-191 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DFEMHAFP_01691 1.6e-17 3.2.1.78 GH26 G Glycosyl hydrolase family 26
DFEMHAFP_01692 5.8e-126 dedA S SNARE associated Golgi protein
DFEMHAFP_01694 7.4e-129 S HAD hydrolase, family IA, variant 3
DFEMHAFP_01695 8.6e-47
DFEMHAFP_01696 3.2e-113 hspR K transcriptional regulator, MerR family
DFEMHAFP_01697 3.9e-158 dnaJ1 O DnaJ molecular chaperone homology domain
DFEMHAFP_01698 2.8e-48 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DFEMHAFP_01699 0.0 dnaK O Heat shock 70 kDa protein
DFEMHAFP_01700 1.3e-145 S Mitochondrial biogenesis AIM24
DFEMHAFP_01701 2.4e-53 phoA 3.1.3.1, 3.1.3.39 P Alkaline phosphatase homologues
DFEMHAFP_01702 1.1e-122 S membrane transporter protein
DFEMHAFP_01703 2e-61 srtC 3.4.22.70 M Sortase family
DFEMHAFP_01704 1.1e-73 srtC 3.4.22.70 M Sortase family
DFEMHAFP_01705 8.3e-193 K Psort location Cytoplasmic, score
DFEMHAFP_01706 1.3e-128 traX S TraX protein
DFEMHAFP_01707 7e-144 S HAD-hyrolase-like
DFEMHAFP_01708 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
DFEMHAFP_01709 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
DFEMHAFP_01710 2.9e-13 S Transposon-encoded protein TnpV
DFEMHAFP_01711 9.7e-109 pepE 3.4.13.21 E Peptidase family S51
DFEMHAFP_01712 4.5e-106 S Protein of unknown function, DUF624
DFEMHAFP_01713 4e-153 rafG G ABC transporter permease
DFEMHAFP_01714 3.7e-154 msmF G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01715 1.7e-182 K Psort location Cytoplasmic, score
DFEMHAFP_01716 7.2e-184 K Periplasmic binding protein-like domain
DFEMHAFP_01717 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
DFEMHAFP_01718 1.2e-255 amyE G Bacterial extracellular solute-binding protein
DFEMHAFP_01719 2.4e-135 G Phosphoglycerate mutase family
DFEMHAFP_01720 1.1e-60 S Protein of unknown function (DUF4235)
DFEMHAFP_01721 1.1e-55 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DFEMHAFP_01722 2.2e-69 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
DFEMHAFP_01723 1.6e-44
DFEMHAFP_01724 2.6e-15 S COG NOG14600 non supervised orthologous group
DFEMHAFP_01726 1.8e-83 K Cro/C1-type HTH DNA-binding domain
DFEMHAFP_01727 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
DFEMHAFP_01728 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
DFEMHAFP_01729 7.7e-126 S Short repeat of unknown function (DUF308)
DFEMHAFP_01730 5.9e-49 S Antitoxin component of a toxin-antitoxin (TA) module
DFEMHAFP_01731 3.4e-55 DJ Addiction module toxin, RelE StbE family
DFEMHAFP_01732 4.5e-13 S Psort location Extracellular, score 8.82
DFEMHAFP_01733 1.1e-231 EGP Major facilitator Superfamily
DFEMHAFP_01734 1.2e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DFEMHAFP_01735 2e-269 KLT Domain of unknown function (DUF4032)
DFEMHAFP_01736 1.6e-210 ugpC E Belongs to the ABC transporter superfamily
DFEMHAFP_01737 1.4e-130 K LytTr DNA-binding domain
DFEMHAFP_01738 2.7e-234 T GHKL domain
DFEMHAFP_01739 3.2e-41
DFEMHAFP_01740 3.9e-214 clcA_2 P Voltage gated chloride channel
DFEMHAFP_01741 5.2e-48 S Psort location Cytoplasmic, score
DFEMHAFP_01742 9.9e-138
DFEMHAFP_01743 2.6e-164 3.4.22.70 M Sortase family
DFEMHAFP_01744 2e-278 M LPXTG-motif cell wall anchor domain protein
DFEMHAFP_01745 0.0 S LPXTG-motif cell wall anchor domain protein
DFEMHAFP_01746 1.3e-72 S GtrA-like protein
DFEMHAFP_01747 0.0 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
DFEMHAFP_01748 3.4e-121 ybjG 3.6.1.27 I Psort location CytoplasmicMembrane, score
DFEMHAFP_01749 5.6e-82 ypeA 2.3.1.1 K Psort location Cytoplasmic, score 8.87
DFEMHAFP_01750 1.1e-113 vex2 V ABC transporter, ATP-binding protein
DFEMHAFP_01751 4.5e-214 vex1 V Efflux ABC transporter, permease protein
DFEMHAFP_01752 9.8e-242 vex3 V ABC transporter permease
DFEMHAFP_01753 9.5e-35 lacS G Psort location CytoplasmicMembrane, score 10.00
DFEMHAFP_01754 2.2e-42 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
DFEMHAFP_01755 2.6e-228 yhjX EGP Major facilitator Superfamily
DFEMHAFP_01756 0.0 trxB1 1.8.1.9 C Thioredoxin domain
DFEMHAFP_01757 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
DFEMHAFP_01758 2.8e-15 S COG NOG14600 non supervised orthologous group
DFEMHAFP_01760 3e-85 I alpha/beta hydrolase fold
DFEMHAFP_01762 8e-145 cobB2 K Sir2 family
DFEMHAFP_01763 4.1e-234 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
DFEMHAFP_01764 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
DFEMHAFP_01765 3.4e-155 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01766 3.9e-157 G Binding-protein-dependent transport system inner membrane component
DFEMHAFP_01767 3.8e-243 msmE7 G Bacterial extracellular solute-binding protein
DFEMHAFP_01768 1.5e-230 nagC GK ROK family
DFEMHAFP_01769 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
DFEMHAFP_01770 1.4e-77 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
DFEMHAFP_01771 0.0 yjcE P Sodium/hydrogen exchanger family
DFEMHAFP_01772 1.2e-154 ypfH S Phospholipase/Carboxylesterase
DFEMHAFP_01773 4e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
DFEMHAFP_01774 8.3e-28
DFEMHAFP_01776 0.0 3.2.1.21 GH3 G Fibronectin type III-like domain
DFEMHAFP_01777 0.0 KLT Protein tyrosine kinase
DFEMHAFP_01778 5.2e-144 O Thioredoxin
DFEMHAFP_01780 6.2e-159 S G5
DFEMHAFP_01781 3e-165 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
DFEMHAFP_01782 9.6e-169 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DFEMHAFP_01783 2.6e-109 S LytR cell envelope-related transcriptional attenuator
DFEMHAFP_01784 1.7e-284 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
DFEMHAFP_01785 1.8e-121 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
DFEMHAFP_01786 0.0 M Conserved repeat domain
DFEMHAFP_01787 4.6e-305 murJ KLT MviN-like protein
DFEMHAFP_01788 0.0 murJ KLT MviN-like protein
DFEMHAFP_01789 4e-13 S Domain of unknown function (DUF4143)
DFEMHAFP_01790 1.4e-121 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
DFEMHAFP_01792 7e-14 S Psort location Extracellular, score 8.82
DFEMHAFP_01793 3.1e-181 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
DFEMHAFP_01794 6.2e-204 parB K Belongs to the ParB family
DFEMHAFP_01795 4.5e-172 parA D CobQ CobB MinD ParA nucleotide binding domain protein
DFEMHAFP_01796 1.2e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
DFEMHAFP_01797 8e-91 jag S Putative single-stranded nucleic acids-binding domain
DFEMHAFP_01798 3.9e-190 yidC U Membrane protein insertase, YidC Oxa1 family
DFEMHAFP_01799 1.5e-43 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
DFEMHAFP_01800 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)