ORF_ID e_value Gene_name EC_number CAZy COGs Description
NMFLEBOF_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NMFLEBOF_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NMFLEBOF_00003 2.4e-33 yaaA S S4 domain
NMFLEBOF_00004 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NMFLEBOF_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
NMFLEBOF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMFLEBOF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NMFLEBOF_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00011 4.8e-179 yaaC S YaaC-like Protein
NMFLEBOF_00012 4e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
NMFLEBOF_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NMFLEBOF_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
NMFLEBOF_00015 1.5e-106 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NMFLEBOF_00016 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NMFLEBOF_00017 1.3e-09
NMFLEBOF_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
NMFLEBOF_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
NMFLEBOF_00020 2.1e-209 yaaH M Glycoside Hydrolase Family
NMFLEBOF_00021 6.5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
NMFLEBOF_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NMFLEBOF_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMFLEBOF_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NMFLEBOF_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NMFLEBOF_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
NMFLEBOF_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
NMFLEBOF_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
NMFLEBOF_00032 1.7e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
NMFLEBOF_00033 6.4e-202 yaaN P Belongs to the TelA family
NMFLEBOF_00034 2.3e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
NMFLEBOF_00035 3.1e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NMFLEBOF_00036 2.2e-54 yaaQ S protein conserved in bacteria
NMFLEBOF_00037 1.5e-71 yaaR S protein conserved in bacteria
NMFLEBOF_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
NMFLEBOF_00039 6.1e-146 yaaT S stage 0 sporulation protein
NMFLEBOF_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
NMFLEBOF_00041 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
NMFLEBOF_00042 2.1e-48 yazA L endonuclease containing a URI domain
NMFLEBOF_00043 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NMFLEBOF_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
NMFLEBOF_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NMFLEBOF_00046 2e-143 tatD L hydrolase, TatD
NMFLEBOF_00047 5.8e-167 rpfB GH23 T protein conserved in bacteria
NMFLEBOF_00048 9.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NMFLEBOF_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NMFLEBOF_00050 1.6e-136 yabG S peptidase
NMFLEBOF_00051 7.8e-39 veg S protein conserved in bacteria
NMFLEBOF_00052 8.3e-27 sspF S DNA topological change
NMFLEBOF_00053 1.6e-160 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NMFLEBOF_00054 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NMFLEBOF_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
NMFLEBOF_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
NMFLEBOF_00057 7.3e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NMFLEBOF_00058 3.6e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NMFLEBOF_00059 2.5e-96 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NMFLEBOF_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NMFLEBOF_00061 2.4e-39 yabK S Peptide ABC transporter permease
NMFLEBOF_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NMFLEBOF_00063 1.5e-92 spoVT K stage V sporulation protein
NMFLEBOF_00064 8.7e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_00065 6.2e-242 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
NMFLEBOF_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
NMFLEBOF_00067 1.5e-49 yabP S Sporulation protein YabP
NMFLEBOF_00068 2.5e-107 yabQ S spore cortex biosynthesis protein
NMFLEBOF_00069 1.1e-44 divIC D Septum formation initiator
NMFLEBOF_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
NMFLEBOF_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
NMFLEBOF_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
NMFLEBOF_00075 9e-184 KLT serine threonine protein kinase
NMFLEBOF_00076 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NMFLEBOF_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NMFLEBOF_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NMFLEBOF_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NMFLEBOF_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NMFLEBOF_00081 1.2e-158 yacD 5.2.1.8 O peptidyl-prolyl isomerase
NMFLEBOF_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMFLEBOF_00084 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00085 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMFLEBOF_00086 7.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
NMFLEBOF_00087 2.1e-165 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
NMFLEBOF_00088 1.2e-157 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NMFLEBOF_00089 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NMFLEBOF_00090 7.9e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NMFLEBOF_00091 4.1e-30 yazB K transcriptional
NMFLEBOF_00092 7e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMFLEBOF_00093 1.4e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NMFLEBOF_00094 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00099 2e-08
NMFLEBOF_00104 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00105 2.9e-76 ctsR K Belongs to the CtsR family
NMFLEBOF_00106 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
NMFLEBOF_00107 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
NMFLEBOF_00108 0.0 clpC O Belongs to the ClpA ClpB family
NMFLEBOF_00109 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NMFLEBOF_00110 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
NMFLEBOF_00111 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
NMFLEBOF_00112 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
NMFLEBOF_00113 7e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
NMFLEBOF_00114 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NMFLEBOF_00115 2.8e-117 cysE 2.3.1.30 E Serine acetyltransferase
NMFLEBOF_00116 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMFLEBOF_00117 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NMFLEBOF_00118 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMFLEBOF_00119 1.2e-88 yacP S RNA-binding protein containing a PIN domain
NMFLEBOF_00120 4.4e-115 sigH K Belongs to the sigma-70 factor family
NMFLEBOF_00121 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NMFLEBOF_00122 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
NMFLEBOF_00123 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NMFLEBOF_00124 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NMFLEBOF_00125 8.7e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NMFLEBOF_00126 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NMFLEBOF_00127 1.6e-106 rsmC 2.1.1.172 J Methyltransferase
NMFLEBOF_00128 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFLEBOF_00129 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFLEBOF_00130 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
NMFLEBOF_00131 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NMFLEBOF_00132 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NMFLEBOF_00133 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NMFLEBOF_00134 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NMFLEBOF_00135 2e-180 ybaC 3.4.11.5 S Alpha/beta hydrolase family
NMFLEBOF_00136 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NMFLEBOF_00137 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NMFLEBOF_00138 3e-105 rplD J Forms part of the polypeptide exit tunnel
NMFLEBOF_00139 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NMFLEBOF_00140 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NMFLEBOF_00141 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NMFLEBOF_00142 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NMFLEBOF_00143 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NMFLEBOF_00144 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NMFLEBOF_00145 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NMFLEBOF_00146 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NMFLEBOF_00147 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NMFLEBOF_00148 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NMFLEBOF_00149 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NMFLEBOF_00150 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMFLEBOF_00151 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NMFLEBOF_00152 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NMFLEBOF_00153 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NMFLEBOF_00154 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NMFLEBOF_00155 1.9e-23 rpmD J Ribosomal protein L30
NMFLEBOF_00156 3.6e-42 rplO J binds to the 23S rRNA
NMFLEBOF_00157 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NMFLEBOF_00158 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NMFLEBOF_00159 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
NMFLEBOF_00160 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NMFLEBOF_00161 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NMFLEBOF_00162 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NMFLEBOF_00163 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NMFLEBOF_00164 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NMFLEBOF_00165 3.6e-58 rplQ J Ribosomal protein L17
NMFLEBOF_00166 1.9e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFLEBOF_00167 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFLEBOF_00168 2.6e-117 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NMFLEBOF_00169 1.4e-141 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NMFLEBOF_00170 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NMFLEBOF_00171 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
NMFLEBOF_00172 1.5e-143 ybaJ Q Methyltransferase domain
NMFLEBOF_00173 9.7e-66 ybaK S Protein of unknown function (DUF2521)
NMFLEBOF_00174 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_00175 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
NMFLEBOF_00176 1.2e-84 gerD
NMFLEBOF_00177 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
NMFLEBOF_00178 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
NMFLEBOF_00179 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00182 2e-08
NMFLEBOF_00186 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00187 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00188 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMFLEBOF_00190 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
NMFLEBOF_00191 7e-141 ybbA S Putative esterase
NMFLEBOF_00192 1.5e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00193 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00194 4e-165 feuA P Iron-uptake system-binding protein
NMFLEBOF_00195 2.3e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
NMFLEBOF_00196 2e-213 ybbC 3.2.1.52 S protein conserved in bacteria
NMFLEBOF_00197 5.2e-16 ybbC 3.2.1.52 S protein conserved in bacteria
NMFLEBOF_00198 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
NMFLEBOF_00199 1.8e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
NMFLEBOF_00200 1.7e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_00201 5.5e-150 ybbH K transcriptional
NMFLEBOF_00202 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NMFLEBOF_00203 7.1e-86 ybbJ J acetyltransferase
NMFLEBOF_00204 4.3e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
NMFLEBOF_00210 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_00211 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
NMFLEBOF_00212 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMFLEBOF_00213 1.5e-224 ybbR S protein conserved in bacteria
NMFLEBOF_00214 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NMFLEBOF_00215 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NMFLEBOF_00218 0.0 papA4 Q amino acid activation for nonribosomal peptide biosynthetic process
NMFLEBOF_00219 1.9e-44 mepB S MepB protein
NMFLEBOF_00220 8.9e-47 pksB 3.1.2.6 S Metallo-beta-lactamase superfamily
NMFLEBOF_00221 1.9e-270 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMFLEBOF_00222 0.0 ybcC S Belongs to the UPF0753 family
NMFLEBOF_00223 6.5e-93 can 4.2.1.1 P carbonic anhydrase
NMFLEBOF_00224 3.9e-47
NMFLEBOF_00225 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
NMFLEBOF_00226 1.5e-50 T Transcriptional regulatory protein, C terminal
NMFLEBOF_00227 1.1e-55 T His Kinase A (phospho-acceptor) domain
NMFLEBOF_00228 3.3e-103 T His Kinase A (phospho-acceptor) domain
NMFLEBOF_00230 5.7e-138 KLT Protein tyrosine kinase
NMFLEBOF_00231 2.9e-151 ybdN
NMFLEBOF_00232 3.6e-216 ybdO S Domain of unknown function (DUF4885)
NMFLEBOF_00233 6.9e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_00234 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00236 1.4e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
NMFLEBOF_00237 4.9e-30 ybxH S Family of unknown function (DUF5370)
NMFLEBOF_00238 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
NMFLEBOF_00239 1.3e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
NMFLEBOF_00240 1.6e-27 ybyB
NMFLEBOF_00241 5.2e-290 ybeC E amino acid
NMFLEBOF_00242 1.3e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMFLEBOF_00243 7.3e-258 glpT G -transporter
NMFLEBOF_00244 8.5e-35 S Protein of unknown function (DUF2651)
NMFLEBOF_00245 2.2e-152 ybfA 3.4.15.5 K FR47-like protein
NMFLEBOF_00246 1.7e-143 ybfB G COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_00247 2.7e-46 ybfB G COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
NMFLEBOF_00251 6.6e-105 ybfH EG EamA-like transporter family
NMFLEBOF_00252 4.4e-144 msmR K AraC-like ligand binding domain
NMFLEBOF_00253 2.8e-33 K sigma factor activity
NMFLEBOF_00254 9e-21 xhlB S SPP1 phage holin
NMFLEBOF_00255 2.3e-164 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
NMFLEBOF_00256 3.9e-57
NMFLEBOF_00257 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NMFLEBOF_00258 8.4e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
NMFLEBOF_00260 2e-166 S Alpha/beta hydrolase family
NMFLEBOF_00261 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMFLEBOF_00262 2.7e-85 ybfM S SNARE associated Golgi protein
NMFLEBOF_00263 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
NMFLEBOF_00264 4.6e-45 ybfN
NMFLEBOF_00265 3.4e-255 S Erythromycin esterase
NMFLEBOF_00266 6.7e-167 ybfP K Transcriptional regulator
NMFLEBOF_00267 1.5e-191 yceA S Belongs to the UPF0176 family
NMFLEBOF_00268 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMFLEBOF_00269 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_00270 1.2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMFLEBOF_00271 4.9e-128 K UTRA
NMFLEBOF_00273 1.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMFLEBOF_00274 2.4e-259 mmuP E amino acid
NMFLEBOF_00275 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
NMFLEBOF_00276 1.4e-30 agcS E Sodium alanine symporter
NMFLEBOF_00277 9.4e-212 agcS E Sodium alanine symporter
NMFLEBOF_00278 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
NMFLEBOF_00279 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
NMFLEBOF_00280 5.8e-169 glnL T Regulator
NMFLEBOF_00281 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
NMFLEBOF_00282 1.9e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMFLEBOF_00283 2.7e-255 gudP G COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_00284 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMFLEBOF_00285 2.1e-123 ycbG K FCD
NMFLEBOF_00286 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
NMFLEBOF_00287 1.2e-174 ycbJ S Macrolide 2'-phosphotransferase
NMFLEBOF_00288 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
NMFLEBOF_00289 6.4e-168 eamA1 EG spore germination
NMFLEBOF_00290 3.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_00291 5.4e-167 T PhoQ Sensor
NMFLEBOF_00292 1.2e-166 ycbN V ABC transporter, ATP-binding protein
NMFLEBOF_00293 7.9e-115 S ABC-2 family transporter protein
NMFLEBOF_00294 4.1e-52 ycbP S Protein of unknown function (DUF2512)
NMFLEBOF_00295 1.3e-78 sleB 3.5.1.28 M Cell wall
NMFLEBOF_00296 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00297 3.3e-135 ycbR T vWA found in TerF C terminus
NMFLEBOF_00298 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
NMFLEBOF_00299 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMFLEBOF_00300 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMFLEBOF_00301 7.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NMFLEBOF_00302 2.8e-202 ycbU E Selenocysteine lyase
NMFLEBOF_00303 1.1e-224 lmrB EGP the major facilitator superfamily
NMFLEBOF_00304 3.1e-101 yxaF K Transcriptional regulator
NMFLEBOF_00305 8.5e-199 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
NMFLEBOF_00306 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMFLEBOF_00307 2e-59 S RDD family
NMFLEBOF_00308 1.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
NMFLEBOF_00309 2.5e-159 2.7.13.3 T GHKL domain
NMFLEBOF_00310 1.2e-126 lytR_2 T LytTr DNA-binding domain
NMFLEBOF_00311 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
NMFLEBOF_00312 4.5e-203 natB CP ABC-2 family transporter protein
NMFLEBOF_00313 1.7e-22 yccK C Aldo keto reductase
NMFLEBOF_00314 8.5e-54 yccK C Aldo keto reductase
NMFLEBOF_00315 3.6e-172 ycdA S Domain of unknown function (DUF5105)
NMFLEBOF_00316 9.4e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_00317 1.4e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_00318 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
NMFLEBOF_00319 7.9e-173 S response regulator aspartate phosphatase
NMFLEBOF_00320 3.7e-137 IQ Enoyl-(Acyl carrier protein) reductase
NMFLEBOF_00321 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
NMFLEBOF_00322 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
NMFLEBOF_00323 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMFLEBOF_00324 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMFLEBOF_00325 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00327 6.1e-85 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMFLEBOF_00328 4.7e-64 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMFLEBOF_00329 7.4e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
NMFLEBOF_00330 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
NMFLEBOF_00331 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
NMFLEBOF_00332 1.4e-136 terC P Protein of unknown function (DUF475)
NMFLEBOF_00333 0.0 yceG S Putative component of 'biosynthetic module'
NMFLEBOF_00334 2e-192 yceH P Belongs to the TelA family
NMFLEBOF_00335 1.6e-216 naiP P Uncharacterised MFS-type transporter YbfB
NMFLEBOF_00336 4.1e-201 yceJ EGP Uncharacterised MFS-type transporter YbfB
NMFLEBOF_00337 2e-144 iscS 2.8.1.7 E Aminotransferase class-V
NMFLEBOF_00338 4.6e-32 S Pfam:DUF1832
NMFLEBOF_00339 5.9e-155 EL AAA domain
NMFLEBOF_00340 2.8e-216 dndC EH COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes
NMFLEBOF_00341 2e-152 dndB L DNA-sulfur modification-associated
NMFLEBOF_00342 1e-110 dptF V Type I site-specific restriction-modification system, R (Restriction) subunit and related
NMFLEBOF_00343 7.1e-70 dptG
NMFLEBOF_00344 0.0 S Domain of unknown function DUF87
NMFLEBOF_00345 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
NMFLEBOF_00346 5.1e-229 proV 3.6.3.32 E glycine betaine
NMFLEBOF_00347 1.3e-127 opuAB P glycine betaine
NMFLEBOF_00348 4.5e-163 opuAC E glycine betaine
NMFLEBOF_00349 1.5e-214 amhX S amidohydrolase
NMFLEBOF_00350 9.6e-256 ycgA S Membrane
NMFLEBOF_00351 4.1e-81 ycgB
NMFLEBOF_00352 1.8e-270 amyE 3.2.1.1 GH13 G alpha-amylase
NMFLEBOF_00353 1.8e-98 amyE 3.2.1.1 GH13 G alpha-amylase
NMFLEBOF_00354 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NMFLEBOF_00355 2.2e-288 lctP C L-lactate permease
NMFLEBOF_00356 7.6e-151 yqcI S YqcI/YcgG family
NMFLEBOF_00357 1.2e-106 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_00358 2.9e-122 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_00359 2.4e-112 ycgI S Domain of unknown function (DUF1989)
NMFLEBOF_00360 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NMFLEBOF_00361 2.5e-109 tmrB S AAA domain
NMFLEBOF_00362 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NMFLEBOF_00363 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
NMFLEBOF_00364 1.2e-177 oxyR3 K LysR substrate binding domain
NMFLEBOF_00365 9.4e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NMFLEBOF_00366 4.1e-144 ycgL S Predicted nucleotidyltransferase
NMFLEBOF_00367 5.1e-170 ycgM E Proline dehydrogenase
NMFLEBOF_00368 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMFLEBOF_00369 3.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMFLEBOF_00370 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
NMFLEBOF_00371 2.6e-147 ycgQ S membrane
NMFLEBOF_00372 1.2e-139 ycgR S permeases
NMFLEBOF_00373 5.1e-156 I alpha/beta hydrolase fold
NMFLEBOF_00374 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
NMFLEBOF_00375 1.6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMFLEBOF_00376 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
NMFLEBOF_00377 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NMFLEBOF_00378 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMFLEBOF_00379 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
NMFLEBOF_00380 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
NMFLEBOF_00381 1e-117 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
NMFLEBOF_00382 1.5e-67 yciB M ErfK YbiS YcfS YnhG
NMFLEBOF_00383 3.6e-112 yciC S GTPases (G3E family)
NMFLEBOF_00384 1.8e-98 yciC S GTPases (G3E family)
NMFLEBOF_00385 5.1e-114 yecS P COG0765 ABC-type amino acid transport system, permease component
NMFLEBOF_00386 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
NMFLEBOF_00389 1e-73 yckC S membrane
NMFLEBOF_00390 1.9e-50 yckD S Protein of unknown function (DUF2680)
NMFLEBOF_00391 5.3e-45 K MarR family
NMFLEBOF_00392 3.4e-20
NMFLEBOF_00393 5.1e-89 S AAA domain
NMFLEBOF_00394 8.7e-17 S AAA domain
NMFLEBOF_00395 9.8e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMFLEBOF_00396 5e-69 nin S Competence protein J (ComJ)
NMFLEBOF_00397 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
NMFLEBOF_00398 9.3e-57 tlpC 2.7.13.3 NT chemotaxis protein
NMFLEBOF_00399 7.8e-115 tlpC 2.7.13.3 NT chemotaxis protein
NMFLEBOF_00400 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
NMFLEBOF_00401 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
NMFLEBOF_00402 1.3e-63 hxlR K transcriptional
NMFLEBOF_00403 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_00404 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_00405 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
NMFLEBOF_00406 5.7e-140 srfAD Q thioesterase
NMFLEBOF_00407 3.5e-222 EGP Major Facilitator Superfamily
NMFLEBOF_00408 3e-88 S YcxB-like protein
NMFLEBOF_00409 1.1e-156 ycxC EG EamA-like transporter family
NMFLEBOF_00410 1.5e-250 ycxD K GntR family transcriptional regulator
NMFLEBOF_00411 5e-114 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
NMFLEBOF_00412 9.7e-115 yczE S membrane
NMFLEBOF_00413 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMFLEBOF_00414 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
NMFLEBOF_00415 4.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
NMFLEBOF_00416 9.2e-161 bsdA K LysR substrate binding domain
NMFLEBOF_00417 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
NMFLEBOF_00418 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
NMFLEBOF_00419 8.9e-39 bsdD 4.1.1.61 S response to toxic substance
NMFLEBOF_00420 6.6e-41 yclD
NMFLEBOF_00421 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
NMFLEBOF_00422 7.8e-261 dtpT E amino acid peptide transporter
NMFLEBOF_00423 2.4e-293 yclG M Pectate lyase superfamily protein
NMFLEBOF_00424 1.1e-191 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00426 9.5e-276 gerKA EG Spore germination protein
NMFLEBOF_00427 8e-227 gerKC S spore germination
NMFLEBOF_00428 7.6e-192 gerKB F Spore germination protein
NMFLEBOF_00429 4e-119 yclH P ABC transporter
NMFLEBOF_00430 1.2e-200 yclI V ABC transporter (permease) YclI
NMFLEBOF_00431 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_00432 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
NMFLEBOF_00433 1.2e-70 S aspartate phosphatase
NMFLEBOF_00436 1.7e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
NMFLEBOF_00437 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00438 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00439 1.8e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
NMFLEBOF_00440 9.4e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
NMFLEBOF_00441 9.2e-251 ycnB EGP Major facilitator Superfamily
NMFLEBOF_00442 5.5e-153 ycnC K Transcriptional regulator
NMFLEBOF_00443 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMFLEBOF_00444 1.6e-45 ycnE S Monooxygenase
NMFLEBOF_00445 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
NMFLEBOF_00446 1.6e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_00447 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMFLEBOF_00448 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMFLEBOF_00449 6.1e-149 glcU U Glucose uptake
NMFLEBOF_00450 9.2e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_00451 6.6e-97 ycnI S protein conserved in bacteria
NMFLEBOF_00452 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
NMFLEBOF_00453 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
NMFLEBOF_00454 7.3e-56
NMFLEBOF_00455 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
NMFLEBOF_00456 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
NMFLEBOF_00457 1.3e-207 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
NMFLEBOF_00458 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
NMFLEBOF_00459 2.1e-09 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMFLEBOF_00460 1.7e-75 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMFLEBOF_00461 1.5e-18 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
NMFLEBOF_00462 4.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NMFLEBOF_00463 8.5e-145 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_00464 3.2e-45 L transposase activity
NMFLEBOF_00465 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
NMFLEBOF_00466 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
NMFLEBOF_00467 2.1e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
NMFLEBOF_00468 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
NMFLEBOF_00469 1.4e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
NMFLEBOF_00470 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
NMFLEBOF_00471 2.7e-132 kipR K Transcriptional regulator
NMFLEBOF_00472 1.3e-119 ycsK E anatomical structure formation involved in morphogenesis
NMFLEBOF_00474 9.2e-49 yczJ S biosynthesis
NMFLEBOF_00475 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
NMFLEBOF_00476 8.3e-173 ydhF S Oxidoreductase
NMFLEBOF_00477 0.0 mtlR K transcriptional regulator, MtlR
NMFLEBOF_00478 2.1e-293 ydaB IQ acyl-CoA ligase
NMFLEBOF_00479 9e-99 ydaC Q Methyltransferase domain
NMFLEBOF_00480 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_00481 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
NMFLEBOF_00482 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMFLEBOF_00483 4.4e-76 ydaG 1.4.3.5 S general stress protein
NMFLEBOF_00484 1.7e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
NMFLEBOF_00485 3.6e-45 ydzA EGP Major facilitator Superfamily
NMFLEBOF_00486 2.5e-74 lrpC K Transcriptional regulator
NMFLEBOF_00487 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMFLEBOF_00488 2.5e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
NMFLEBOF_00489 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NMFLEBOF_00490 1.8e-27
NMFLEBOF_00491 1.8e-72 sdpB S Protein conserved in bacteria
NMFLEBOF_00493 2.1e-39
NMFLEBOF_00494 3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
NMFLEBOF_00496 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
NMFLEBOF_00497 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
NMFLEBOF_00499 3.4e-58 ydbB G Cupin domain
NMFLEBOF_00500 2.6e-61 ydbC S Domain of unknown function (DUF4937
NMFLEBOF_00501 7.9e-154 ydbD P Catalase
NMFLEBOF_00502 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
NMFLEBOF_00503 1.6e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMFLEBOF_00504 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
NMFLEBOF_00505 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMFLEBOF_00506 9.7e-181 ydbI S AI-2E family transporter
NMFLEBOF_00507 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
NMFLEBOF_00508 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMFLEBOF_00509 2.7e-52 ydbL
NMFLEBOF_00510 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
NMFLEBOF_00511 1.1e-18 S Fur-regulated basic protein B
NMFLEBOF_00512 2.2e-07 S Fur-regulated basic protein A
NMFLEBOF_00513 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMFLEBOF_00514 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMFLEBOF_00515 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NMFLEBOF_00516 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NMFLEBOF_00517 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NMFLEBOF_00518 2.1e-82 ydbS S Bacterial PH domain
NMFLEBOF_00519 3.1e-257 ydbT S Membrane
NMFLEBOF_00520 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
NMFLEBOF_00521 1.4e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NMFLEBOF_00522 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
NMFLEBOF_00523 9.6e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMFLEBOF_00524 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
NMFLEBOF_00525 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
NMFLEBOF_00526 1.3e-143 rsbR T Positive regulator of sigma-B
NMFLEBOF_00527 5.2e-57 rsbS T antagonist
NMFLEBOF_00528 8.5e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
NMFLEBOF_00529 3.5e-188 rsbU 3.1.3.3 KT phosphatase
NMFLEBOF_00530 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
NMFLEBOF_00531 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
NMFLEBOF_00532 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_00533 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
NMFLEBOF_00534 0.0 yhgF K COG2183 Transcriptional accessory protein
NMFLEBOF_00535 8.9e-83 ydcK S Belongs to the SprT family
NMFLEBOF_00543 3.2e-114 yecA E amino acid
NMFLEBOF_00544 4.6e-107 K Transcriptional regulator
NMFLEBOF_00545 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
NMFLEBOF_00546 8.5e-45
NMFLEBOF_00547 3e-139 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMFLEBOF_00548 3.4e-33 K Helix-turn-helix XRE-family like proteins
NMFLEBOF_00549 1.9e-40
NMFLEBOF_00553 7e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NMFLEBOF_00554 8.7e-30 cspL K Cold shock
NMFLEBOF_00555 2.3e-78 carD K Transcription factor
NMFLEBOF_00556 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00558 1.6e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMFLEBOF_00559 5.8e-163 rhaS5 K AraC-like ligand binding domain
NMFLEBOF_00560 3.7e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
NMFLEBOF_00561 6.9e-164 ydeE K AraC family transcriptional regulator
NMFLEBOF_00562 6.6e-262 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_00563 4e-154 ydeG EGP Major facilitator superfamily
NMFLEBOF_00564 2.7e-103 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
NMFLEBOF_00566 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00567 1.5e-102
NMFLEBOF_00568 1.1e-31 S SNARE associated Golgi protein
NMFLEBOF_00569 1.8e-14 ptsH G PTS HPr component phosphorylation site
NMFLEBOF_00570 3.4e-84 K Transcriptional regulator C-terminal region
NMFLEBOF_00571 1.8e-153 ydeK EG -transporter
NMFLEBOF_00572 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_00573 1.3e-72 maoC I N-terminal half of MaoC dehydratase
NMFLEBOF_00574 1.8e-104 ydeN S Serine hydrolase
NMFLEBOF_00575 5.7e-55 K HxlR-like helix-turn-helix
NMFLEBOF_00576 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMFLEBOF_00577 8.2e-57 arsR K transcriptional
NMFLEBOF_00578 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMFLEBOF_00580 3.7e-145 ydfB J GNAT acetyltransferase
NMFLEBOF_00581 5.2e-154 ydfC EG EamA-like transporter family
NMFLEBOF_00582 2.5e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_00583 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
NMFLEBOF_00584 1.9e-115 ydfE S Flavin reductase like domain
NMFLEBOF_00585 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
NMFLEBOF_00586 1e-14 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMFLEBOF_00588 2.7e-176 ydfH 2.7.13.3 T Histidine kinase
NMFLEBOF_00589 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_00590 0.0 ydfJ S drug exporters of the RND superfamily
NMFLEBOF_00591 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00594 2.9e-173 S Alpha/beta hydrolase family
NMFLEBOF_00595 7.2e-116 S Protein of unknown function (DUF554)
NMFLEBOF_00596 9.2e-147 K Bacterial transcription activator, effector binding domain
NMFLEBOF_00597 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMFLEBOF_00598 2.6e-109 ydfN C nitroreductase
NMFLEBOF_00599 4.4e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
NMFLEBOF_00600 5.2e-46 mhqP S DoxX
NMFLEBOF_00601 8.5e-54 traF CO Thioredoxin
NMFLEBOF_00602 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
NMFLEBOF_00603 4.8e-29
NMFLEBOF_00605 2.2e-117 ydfR S Protein of unknown function (DUF421)
NMFLEBOF_00606 1.5e-121 ydfS S Protein of unknown function (DUF421)
NMFLEBOF_00607 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
NMFLEBOF_00608 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
NMFLEBOF_00609 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
NMFLEBOF_00610 1.7e-97 K Bacterial regulatory proteins, tetR family
NMFLEBOF_00611 4.8e-52 S DoxX-like family
NMFLEBOF_00612 2.9e-84 yycN 2.3.1.128 K Acetyltransferase
NMFLEBOF_00613 3.2e-295 expZ S ABC transporter
NMFLEBOF_00614 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_00615 5.6e-89 dinB S DinB family
NMFLEBOF_00616 1.8e-79 K helix_turn_helix multiple antibiotic resistance protein
NMFLEBOF_00617 0.0 ydgH S drug exporters of the RND superfamily
NMFLEBOF_00618 1e-113 drgA C nitroreductase
NMFLEBOF_00619 7.1e-69 ydgJ K Winged helix DNA-binding domain
NMFLEBOF_00620 2.2e-208 tcaB EGP Major facilitator Superfamily
NMFLEBOF_00621 1.2e-121 ydhB S membrane transporter protein
NMFLEBOF_00622 5.5e-121 ydhC K FCD
NMFLEBOF_00623 4.2e-231 ydhD M Glycosyl hydrolase
NMFLEBOF_00624 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMFLEBOF_00625 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00627 1.3e-125
NMFLEBOF_00628 9.9e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMFLEBOF_00629 4.3e-67 frataxin S Domain of unknown function (DU1801)
NMFLEBOF_00631 2.9e-84 K Acetyltransferase (GNAT) domain
NMFLEBOF_00632 8.4e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NMFLEBOF_00633 2.3e-99 ydhK M Protein of unknown function (DUF1541)
NMFLEBOF_00634 1.8e-199 pbuE EGP Major facilitator Superfamily
NMFLEBOF_00635 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMFLEBOF_00636 1.9e-30 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMFLEBOF_00637 6.4e-137 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFLEBOF_00638 2.2e-91 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFLEBOF_00639 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMFLEBOF_00640 3.3e-132 ydhQ K UTRA
NMFLEBOF_00641 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
NMFLEBOF_00642 3.5e-07 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMFLEBOF_00643 5.2e-61 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMFLEBOF_00644 1.2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
NMFLEBOF_00645 1.8e-133 ydhU P Catalase
NMFLEBOF_00648 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_00649 7.8e-08
NMFLEBOF_00651 7.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NMFLEBOF_00652 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
NMFLEBOF_00653 1.9e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
NMFLEBOF_00654 8.1e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
NMFLEBOF_00655 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NMFLEBOF_00656 0.0 ydiF S ABC transporter
NMFLEBOF_00657 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
NMFLEBOF_00658 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NMFLEBOF_00659 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
NMFLEBOF_00660 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NMFLEBOF_00661 2.9e-27 ydiK S Domain of unknown function (DUF4305)
NMFLEBOF_00662 7.9e-129 ydiL S CAAX protease self-immunity
NMFLEBOF_00663 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NMFLEBOF_00664 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NMFLEBOF_00665 2.2e-144 L Belongs to the 'phage' integrase family
NMFLEBOF_00666 4.7e-48 xkdA E IrrE N-terminal-like domain
NMFLEBOF_00667 3.5e-21 ansR K transcriptional
NMFLEBOF_00668 4e-18 K Helix-turn-helix XRE-family like proteins
NMFLEBOF_00669 3.1e-34
NMFLEBOF_00670 2.1e-41 S Phage regulatory protein Rha (Phage_pRha)
NMFLEBOF_00671 2.4e-85
NMFLEBOF_00676 3.1e-98
NMFLEBOF_00677 1.3e-65 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
NMFLEBOF_00679 7.3e-76 L DnaD domain protein
NMFLEBOF_00680 2e-80 xkdC L IstB-like ATP binding protein
NMFLEBOF_00682 8.2e-62 rusA L Endodeoxyribonuclease RusA
NMFLEBOF_00683 6.6e-25 yqaO S Phage-like element PBSX protein XtrA
NMFLEBOF_00686 1.3e-26
NMFLEBOF_00687 6.2e-115
NMFLEBOF_00689 4.2e-80 L Transposase
NMFLEBOF_00690 1.2e-28
NMFLEBOF_00691 1.2e-50 V HNH endonuclease
NMFLEBOF_00692 3.1e-79 L phage terminase small subunit
NMFLEBOF_00693 6.4e-307 S Terminase
NMFLEBOF_00695 4.8e-238 S Phage portal protein
NMFLEBOF_00696 4.1e-117 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NMFLEBOF_00697 1.4e-210 S capsid protein
NMFLEBOF_00698 1.7e-20
NMFLEBOF_00699 2.2e-37 S Phage gp6-like head-tail connector protein
NMFLEBOF_00700 3.6e-38 S Phage head-tail joining protein
NMFLEBOF_00701 1.4e-50 S Bacteriophage HK97-gp10, putative tail-component
NMFLEBOF_00703 1.4e-78 N Phage major tail protein phi13
NMFLEBOF_00706 0.0 D phage tail tape measure protein
NMFLEBOF_00707 5.7e-107 S Phage tail protein
NMFLEBOF_00708 3.5e-220 NU Prophage endopeptidase tail
NMFLEBOF_00709 6.5e-250
NMFLEBOF_00710 5.6e-195 S Domain of unknown function (DUF2479)
NMFLEBOF_00711 3.7e-16
NMFLEBOF_00713 1.1e-27 bhlA S BhlA holin family
NMFLEBOF_00714 6e-31 xhlB S SPP1 phage holin
NMFLEBOF_00715 1.4e-130 xlyB 3.5.1.104, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
NMFLEBOF_00716 8.3e-67 S Immunity protein 70
NMFLEBOF_00717 4.1e-178 A Pre-toxin TG
NMFLEBOF_00718 1.9e-12 S Membrane
NMFLEBOF_00719 9e-41 S protein domain associated with
NMFLEBOF_00721 1.6e-27 K Helix-turn-helix domain
NMFLEBOF_00723 8.7e-27 U Preprotein translocase subunit SecB
NMFLEBOF_00724 1.7e-11
NMFLEBOF_00725 1.4e-13
NMFLEBOF_00727 6e-114 cll
NMFLEBOF_00728 5e-136
NMFLEBOF_00729 0.0 K NB-ARC domain
NMFLEBOF_00730 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
NMFLEBOF_00731 3.1e-251 gutA G MFS/sugar transport protein
NMFLEBOF_00732 1.2e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
NMFLEBOF_00733 3.3e-113 pspA KT Phage shock protein A
NMFLEBOF_00734 7.5e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMFLEBOF_00735 2.5e-130 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
NMFLEBOF_00736 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
NMFLEBOF_00737 4.1e-144 S Ion transport 2 domain protein
NMFLEBOF_00738 5.3e-27 S Ion transport 2 domain protein
NMFLEBOF_00739 1.7e-257 iolT EGP Major facilitator Superfamily
NMFLEBOF_00740 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
NMFLEBOF_00741 4.5e-64 ydjM M Lytic transglycolase
NMFLEBOF_00742 6.1e-151 ydjN U Involved in the tonB-independent uptake of proteins
NMFLEBOF_00743 1.4e-45 L transposase activity
NMFLEBOF_00744 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_00746 1.2e-34 ydjO S Cold-inducible protein YdjO
NMFLEBOF_00747 2e-157 ydjP I Alpha/beta hydrolase family
NMFLEBOF_00748 4.4e-80 yeaA S Protein of unknown function (DUF4003)
NMFLEBOF_00749 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
NMFLEBOF_00750 3.3e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_00751 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NMFLEBOF_00752 5e-176 yeaC S COG0714 MoxR-like ATPases
NMFLEBOF_00753 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
NMFLEBOF_00754 0.0 yebA E COG1305 Transglutaminase-like enzymes
NMFLEBOF_00755 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NMFLEBOF_00756 8.6e-85 K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_00757 5.8e-248 S Domain of unknown function (DUF4179)
NMFLEBOF_00758 2.5e-210 pbuG S permease
NMFLEBOF_00759 2.3e-118 yebC M Membrane
NMFLEBOF_00760 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00763 4e-93 yebE S UPF0316 protein
NMFLEBOF_00764 8e-28 yebG S NETI protein
NMFLEBOF_00765 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NMFLEBOF_00766 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NMFLEBOF_00767 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NMFLEBOF_00768 3.7e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
NMFLEBOF_00769 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFLEBOF_00770 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFLEBOF_00771 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NMFLEBOF_00772 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NMFLEBOF_00773 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
NMFLEBOF_00774 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NMFLEBOF_00775 4.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
NMFLEBOF_00776 5e-232 purD 6.3.4.13 F Belongs to the GARS family
NMFLEBOF_00777 8.2e-70 K helix_turn_helix ASNC type
NMFLEBOF_00778 1.3e-188 yjeH E Amino acid permease
NMFLEBOF_00779 2.7e-27 S Protein of unknown function (DUF2892)
NMFLEBOF_00780 0.0 yerA 3.5.4.2 F adenine deaminase
NMFLEBOF_00781 4.9e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
NMFLEBOF_00782 2.4e-50 yerC S protein conserved in bacteria
NMFLEBOF_00783 1.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
NMFLEBOF_00785 3.2e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
NMFLEBOF_00786 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NMFLEBOF_00787 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NMFLEBOF_00788 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
NMFLEBOF_00789 3.5e-196 yerI S homoserine kinase type II (protein kinase fold)
NMFLEBOF_00790 1.6e-123 sapB S MgtC SapB transporter
NMFLEBOF_00791 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMFLEBOF_00792 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMFLEBOF_00793 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NMFLEBOF_00794 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NMFLEBOF_00795 2.5e-147 yerO K Transcriptional regulator
NMFLEBOF_00796 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NMFLEBOF_00797 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMFLEBOF_00798 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMFLEBOF_00799 0.0 L Type III restriction enzyme res subunit
NMFLEBOF_00801 5.8e-43
NMFLEBOF_00803 1.4e-100 S response regulator aspartate phosphatase
NMFLEBOF_00805 2.7e-27
NMFLEBOF_00806 4.2e-75 S Protein of unknown function, DUF600
NMFLEBOF_00807 0.0 L nucleic acid phosphodiester bond hydrolysis
NMFLEBOF_00809 8.7e-101 L endonuclease activity
NMFLEBOF_00810 5.7e-49
NMFLEBOF_00811 1.6e-210 S Tetratricopeptide repeat
NMFLEBOF_00813 2.7e-126 yeeN K transcriptional regulatory protein
NMFLEBOF_00815 8.5e-102 dhaR3 K Transcriptional regulator
NMFLEBOF_00816 2.5e-77 yesE S SnoaL-like domain
NMFLEBOF_00817 3.2e-150 yesF GM NAD(P)H-binding
NMFLEBOF_00818 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
NMFLEBOF_00819 1.5e-45 cotJB S CotJB protein
NMFLEBOF_00820 2e-103 cotJC P Spore Coat
NMFLEBOF_00821 1.3e-101 yesJ K Acetyltransferase (GNAT) family
NMFLEBOF_00822 1.2e-101 yesL S Protein of unknown function, DUF624
NMFLEBOF_00823 0.0 yesM 2.7.13.3 T Histidine kinase
NMFLEBOF_00824 1e-128 yesN K helix_turn_helix, arabinose operon control protein
NMFLEBOF_00825 8.3e-41 yesN K helix_turn_helix, arabinose operon control protein
NMFLEBOF_00826 8e-246 yesO G Bacterial extracellular solute-binding protein
NMFLEBOF_00827 1.3e-60 yesP G Binding-protein-dependent transport system inner membrane component
NMFLEBOF_00828 1.4e-95 yesP G Binding-protein-dependent transport system inner membrane component
NMFLEBOF_00829 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
NMFLEBOF_00830 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
NMFLEBOF_00831 0.0 yesS K Transcriptional regulator
NMFLEBOF_00832 5e-133 E GDSL-like Lipase/Acylhydrolase
NMFLEBOF_00833 4.6e-128 yesU S Domain of unknown function (DUF1961)
NMFLEBOF_00834 1.7e-111 yesV S Protein of unknown function, DUF624
NMFLEBOF_00835 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMFLEBOF_00836 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
NMFLEBOF_00837 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
NMFLEBOF_00838 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
NMFLEBOF_00839 4.2e-104 yetA
NMFLEBOF_00840 0.0 yetA
NMFLEBOF_00841 1.5e-288 lplA G Bacterial extracellular solute-binding protein
NMFLEBOF_00842 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMFLEBOF_00843 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
NMFLEBOF_00844 1.7e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMFLEBOF_00845 4e-122 yetF S membrane
NMFLEBOF_00846 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
NMFLEBOF_00847 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_00848 2.4e-34
NMFLEBOF_00849 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMFLEBOF_00850 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
NMFLEBOF_00851 2.6e-104 yetJ S Belongs to the BI1 family
NMFLEBOF_00852 8.3e-31 yetM CH FAD binding domain
NMFLEBOF_00853 3.5e-104 mrr L restriction endonuclease
NMFLEBOF_00854 3.5e-194 yetN S Protein of unknown function (DUF3900)
NMFLEBOF_00855 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMFLEBOF_00856 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMFLEBOF_00857 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
NMFLEBOF_00858 1.9e-186 yfnG 4.2.1.45 M dehydratase
NMFLEBOF_00859 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
NMFLEBOF_00860 1.4e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
NMFLEBOF_00861 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
NMFLEBOF_00862 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_00863 3.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NMFLEBOF_00864 6.4e-241 yfnA E amino acid
NMFLEBOF_00865 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMFLEBOF_00866 1.1e-113 yfmS NT chemotaxis protein
NMFLEBOF_00867 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMFLEBOF_00868 7.5e-74 yfmQ S Uncharacterised protein from bacillus cereus group
NMFLEBOF_00869 4.2e-76 yfmP K transcriptional
NMFLEBOF_00870 1.5e-209 yfmO EGP Major facilitator Superfamily
NMFLEBOF_00871 7.7e-29
NMFLEBOF_00872 1.4e-45 L transposase activity
NMFLEBOF_00873 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_00874 1.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMFLEBOF_00875 2.5e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
NMFLEBOF_00876 5.2e-75 yfmK 2.3.1.128 K acetyltransferase
NMFLEBOF_00877 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_00878 2.1e-188 yfmJ S N-terminal domain of oxidoreductase
NMFLEBOF_00879 5.7e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
NMFLEBOF_00880 6.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00881 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00882 3.6e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
NMFLEBOF_00883 2.9e-24 S Protein of unknown function (DUF3212)
NMFLEBOF_00884 7.6e-58 yflT S Heat induced stress protein YflT
NMFLEBOF_00885 9.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
NMFLEBOF_00886 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
NMFLEBOF_00887 1.8e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMFLEBOF_00888 2.2e-117 citT T response regulator
NMFLEBOF_00889 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
NMFLEBOF_00890 8.5e-227 citM C Citrate transporter
NMFLEBOF_00891 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
NMFLEBOF_00892 8.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
NMFLEBOF_00893 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NMFLEBOF_00894 6.4e-122 yflK S protein conserved in bacteria
NMFLEBOF_00895 8.9e-18 yflJ S Protein of unknown function (DUF2639)
NMFLEBOF_00896 4.1e-19 yflI
NMFLEBOF_00897 5.9e-49 yflH S Protein of unknown function (DUF3243)
NMFLEBOF_00898 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
NMFLEBOF_00899 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
NMFLEBOF_00900 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMFLEBOF_00901 6e-67 yhdN S Domain of unknown function (DUF1992)
NMFLEBOF_00902 8.8e-34 yfkQ EG Spore germination protein
NMFLEBOF_00903 3.2e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_00904 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
NMFLEBOF_00905 1.8e-133 treR K transcriptional
NMFLEBOF_00906 1.1e-124 yfkO C nitroreductase
NMFLEBOF_00907 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NMFLEBOF_00908 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
NMFLEBOF_00909 1.1e-204 ydiM EGP Major facilitator Superfamily
NMFLEBOF_00910 1.3e-28 yfkK S Belongs to the UPF0435 family
NMFLEBOF_00911 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMFLEBOF_00912 2.4e-50 yfkI S gas vesicle protein
NMFLEBOF_00913 1.3e-143 yihY S Belongs to the UPF0761 family
NMFLEBOF_00914 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_00915 1.8e-182 cax P COG0387 Ca2 H antiporter
NMFLEBOF_00916 1.2e-146 yfkD S YfkD-like protein
NMFLEBOF_00917 6e-149 yfkC M Mechanosensitive ion channel
NMFLEBOF_00918 5.4e-222 yfkA S YfkB-like domain
NMFLEBOF_00919 1.1e-26 yfjT
NMFLEBOF_00920 1.7e-153 pdaA G deacetylase
NMFLEBOF_00921 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
NMFLEBOF_00922 1e-181 corA P Mediates influx of magnesium ions
NMFLEBOF_00923 1.7e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
NMFLEBOF_00924 2.4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NMFLEBOF_00925 3.9e-44 S YfzA-like protein
NMFLEBOF_00926 2.4e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NMFLEBOF_00927 1.9e-85 yfjM S Psort location Cytoplasmic, score
NMFLEBOF_00928 2.3e-29 yfjL
NMFLEBOF_00929 4.9e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMFLEBOF_00930 2.8e-188 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMFLEBOF_00931 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMFLEBOF_00932 5.6e-253 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMFLEBOF_00933 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
NMFLEBOF_00934 1.7e-24 sspH S Belongs to the SspH family
NMFLEBOF_00935 1.1e-55 yfjF S UPF0060 membrane protein
NMFLEBOF_00936 4.1e-82 S Family of unknown function (DUF5381)
NMFLEBOF_00937 1.8e-101 yfjD S Family of unknown function (DUF5381)
NMFLEBOF_00938 9e-144 yfjC
NMFLEBOF_00939 2.7e-190 yfjB
NMFLEBOF_00940 1.1e-44 yfjA S Belongs to the WXG100 family
NMFLEBOF_00941 2.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMFLEBOF_00942 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
NMFLEBOF_00943 2e-294 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_00944 4.2e-306 yfiB3 V ABC transporter
NMFLEBOF_00945 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMFLEBOF_00946 4.1e-63 mhqP S DoxX
NMFLEBOF_00947 2.2e-162 yfiE 1.13.11.2 S glyoxalase
NMFLEBOF_00948 1.9e-220 yxjM T Histidine kinase
NMFLEBOF_00949 1e-111 KT LuxR family transcriptional regulator
NMFLEBOF_00950 7.1e-167 V ABC transporter, ATP-binding protein
NMFLEBOF_00951 2.9e-205 V ABC-2 family transporter protein
NMFLEBOF_00952 4e-204 V COG0842 ABC-type multidrug transport system, permease component
NMFLEBOF_00953 8.3e-99 padR K transcriptional
NMFLEBOF_00954 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
NMFLEBOF_00955 7.6e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
NMFLEBOF_00956 3.8e-108 yfiR K Transcriptional regulator
NMFLEBOF_00957 1.5e-209 yfiS EGP Major facilitator Superfamily
NMFLEBOF_00958 1.8e-98 yfiT S Belongs to the metal hydrolase YfiT family
NMFLEBOF_00959 2.3e-229 yfiU EGP Major facilitator Superfamily
NMFLEBOF_00960 6.6e-18 yfiU EGP Major facilitator Superfamily
NMFLEBOF_00961 4.9e-79 yfiV K transcriptional
NMFLEBOF_00962 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NMFLEBOF_00964 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_00965 6.7e-176 yfiY P ABC transporter substrate-binding protein
NMFLEBOF_00966 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00967 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_00968 2.4e-164 yfhB 5.3.3.17 S PhzF family
NMFLEBOF_00969 1.5e-106 yfhC C nitroreductase
NMFLEBOF_00970 2.1e-25 yfhD S YfhD-like protein
NMFLEBOF_00972 7.9e-171 yfhF S nucleoside-diphosphate sugar epimerase
NMFLEBOF_00973 5.7e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
NMFLEBOF_00974 9.7e-52 yfhH S Protein of unknown function (DUF1811)
NMFLEBOF_00976 1.1e-209 yfhI EGP Major facilitator Superfamily
NMFLEBOF_00977 6.2e-20 sspK S reproduction
NMFLEBOF_00978 1.3e-44 yfhJ S WVELL protein
NMFLEBOF_00979 2.7e-91 batE T Bacterial SH3 domain homologues
NMFLEBOF_00980 1.7e-50 yfhL S SdpI/YhfL protein family
NMFLEBOF_00981 1.3e-170 yfhM S Alpha beta hydrolase
NMFLEBOF_00982 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMFLEBOF_00983 0.0 yfhO S Bacterial membrane protein YfhO
NMFLEBOF_00984 1.2e-185 yfhP S membrane-bound metal-dependent
NMFLEBOF_00985 1.1e-210 mutY L A G-specific
NMFLEBOF_00986 6.9e-36 yfhS
NMFLEBOF_00987 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_00988 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
NMFLEBOF_00989 1.5e-37 ygaB S YgaB-like protein
NMFLEBOF_00990 1.3e-104 ygaC J Belongs to the UPF0374 family
NMFLEBOF_00991 1.8e-301 ygaD V ABC transporter
NMFLEBOF_00992 1.6e-178 ygaE S Membrane
NMFLEBOF_00993 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMFLEBOF_00994 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
NMFLEBOF_00995 4e-80 perR P Belongs to the Fur family
NMFLEBOF_00996 9.5e-56 ygzB S UPF0295 protein
NMFLEBOF_00997 6.7e-167 ygxA S Nucleotidyltransferase-like
NMFLEBOF_00998 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_01003 7.8e-08
NMFLEBOF_01011 2e-08
NMFLEBOF_01015 1.4e-45 L transposase activity
NMFLEBOF_01016 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_01017 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01019 5e-142 spo0M S COG4326 Sporulation control protein
NMFLEBOF_01020 1.2e-26
NMFLEBOF_01021 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
NMFLEBOF_01022 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NMFLEBOF_01024 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMFLEBOF_01025 1.9e-138 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
NMFLEBOF_01026 2.4e-165 ssuA M Sulfonate ABC transporter
NMFLEBOF_01027 3e-145 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMFLEBOF_01028 7.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
NMFLEBOF_01031 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NMFLEBOF_01032 1.4e-75 ygaO
NMFLEBOF_01033 4.4e-29 K Transcriptional regulator
NMFLEBOF_01035 9.7e-112 yhzB S B3/4 domain
NMFLEBOF_01036 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
NMFLEBOF_01037 2.4e-175 yhbB S Putative amidase domain
NMFLEBOF_01038 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NMFLEBOF_01039 6e-109 yhbD K Protein of unknown function (DUF4004)
NMFLEBOF_01040 1.3e-56 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMFLEBOF_01041 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
NMFLEBOF_01042 0.0 prkA T Ser protein kinase
NMFLEBOF_01043 2.5e-225 yhbH S Belongs to the UPF0229 family
NMFLEBOF_01044 2.2e-76 yhbI K DNA-binding transcription factor activity
NMFLEBOF_01045 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
NMFLEBOF_01046 9.9e-270 yhcA EGP Major facilitator Superfamily
NMFLEBOF_01047 5.2e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
NMFLEBOF_01048 2.8e-37 yhcC
NMFLEBOF_01049 6e-55
NMFLEBOF_01050 5.6e-59 yhcF K Transcriptional regulator
NMFLEBOF_01051 8.8e-122 yhcG V ABC transporter, ATP-binding protein
NMFLEBOF_01052 5.5e-164 yhcH V ABC transporter, ATP-binding protein
NMFLEBOF_01053 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMFLEBOF_01054 1e-30 cspB K Cold-shock protein
NMFLEBOF_01055 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
NMFLEBOF_01056 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
NMFLEBOF_01057 1.5e-218 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMFLEBOF_01058 7.7e-177 A Pre-toxin TG
NMFLEBOF_01059 2.5e-63 S Immunity protein 70
NMFLEBOF_01061 1.6e-16 S Domain of unknown function (DUF4935)
NMFLEBOF_01063 2e-49 L Belongs to the 'phage' integrase family
NMFLEBOF_01065 1.9e-44 yddA
NMFLEBOF_01069 9.5e-168 yddB S Conjugative transposon protein TcpC
NMFLEBOF_01070 2e-39 yddC
NMFLEBOF_01071 6.1e-91 yddD S TcpE family
NMFLEBOF_01072 8.5e-218 yddE S AAA-like domain
NMFLEBOF_01073 1.4e-195 yddE S AAA-like domain
NMFLEBOF_01074 1.4e-53 S Domain of unknown function (DUF1874)
NMFLEBOF_01075 0.0 yddG S maturation of SSU-rRNA
NMFLEBOF_01076 1.2e-185 yddH CBM50 M Lysozyme-like
NMFLEBOF_01077 2.4e-84 yddI
NMFLEBOF_01078 2.4e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
NMFLEBOF_01079 5e-57 S Domain of unknown function (DUF4145)
NMFLEBOF_01080 1.7e-69 S response regulator aspartate phosphatase
NMFLEBOF_01082 1.2e-39 yhcM
NMFLEBOF_01083 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMFLEBOF_01084 3.8e-158 yhcP
NMFLEBOF_01085 2.5e-83 yhcQ M Spore coat protein
NMFLEBOF_01086 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
NMFLEBOF_01087 1e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
NMFLEBOF_01088 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMFLEBOF_01089 9.3e-68 yhcU S Family of unknown function (DUF5365)
NMFLEBOF_01090 3.8e-67 yhcV S COG0517 FOG CBS domain
NMFLEBOF_01091 1e-119 yhcW 5.4.2.6 S hydrolase
NMFLEBOF_01092 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMFLEBOF_01093 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMFLEBOF_01094 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
NMFLEBOF_01095 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
NMFLEBOF_01096 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NMFLEBOF_01097 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NMFLEBOF_01098 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
NMFLEBOF_01099 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
NMFLEBOF_01100 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_01101 1.2e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
NMFLEBOF_01102 1.2e-38 yhdB S YhdB-like protein
NMFLEBOF_01103 1.8e-53 yhdC S Protein of unknown function (DUF3889)
NMFLEBOF_01104 5.7e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMFLEBOF_01105 1e-75 nsrR K Transcriptional regulator
NMFLEBOF_01107 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01108 7.3e-238 ygxB M Conserved TM helix
NMFLEBOF_01109 6.3e-276 ycgB S Stage V sporulation protein R
NMFLEBOF_01110 1.1e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
NMFLEBOF_01111 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMFLEBOF_01112 3.8e-162 citR K Transcriptional regulator
NMFLEBOF_01113 3.2e-203 citA 2.3.3.1 C Belongs to the citrate synthase family
NMFLEBOF_01114 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_01115 3.4e-250 yhdG E amino acid
NMFLEBOF_01116 3.7e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMFLEBOF_01117 4.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_01118 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_01119 8.1e-45 yhdK S Sigma-M inhibitor protein
NMFLEBOF_01120 3.3e-200 yhdL S Sigma factor regulator N-terminal
NMFLEBOF_01121 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_01122 1.7e-190 yhdN C Aldo keto reductase
NMFLEBOF_01123 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMFLEBOF_01124 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMFLEBOF_01125 4.1e-74 cueR K transcriptional
NMFLEBOF_01126 6.4e-73 yhdR 2.6.1.1 E Aminotransferase
NMFLEBOF_01127 1.9e-135 yhdR 2.6.1.1 E Aminotransferase
NMFLEBOF_01128 2.3e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
NMFLEBOF_01129 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMFLEBOF_01130 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NMFLEBOF_01131 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMFLEBOF_01133 5.6e-203 yhdY M Mechanosensitive ion channel
NMFLEBOF_01134 7.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
NMFLEBOF_01135 2.4e-145 yheN G deacetylase
NMFLEBOF_01136 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
NMFLEBOF_01137 5.7e-226 nhaC C Na H antiporter
NMFLEBOF_01138 1.5e-83 nhaX T Belongs to the universal stress protein A family
NMFLEBOF_01139 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMFLEBOF_01140 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMFLEBOF_01141 4.5e-109 yheG GM NAD(P)H-binding
NMFLEBOF_01142 6.3e-28 sspB S spore protein
NMFLEBOF_01143 1.3e-36 yheE S Family of unknown function (DUF5342)
NMFLEBOF_01144 8.2e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
NMFLEBOF_01145 1.6e-215 yheC HJ YheC/D like ATP-grasp
NMFLEBOF_01146 1.4e-201 yheB S Belongs to the UPF0754 family
NMFLEBOF_01147 9.5e-48 yheA S Belongs to the UPF0342 family
NMFLEBOF_01148 5.3e-104 yhaZ L DNA alkylation repair enzyme
NMFLEBOF_01149 2.9e-73 yhaZ L DNA alkylation repair enzyme
NMFLEBOF_01150 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
NMFLEBOF_01151 1.8e-292 hemZ H coproporphyrinogen III oxidase
NMFLEBOF_01152 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
NMFLEBOF_01153 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMFLEBOF_01155 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
NMFLEBOF_01156 3.2e-26 S YhzD-like protein
NMFLEBOF_01157 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
NMFLEBOF_01158 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
NMFLEBOF_01159 6.8e-226 yhaO L DNA repair exonuclease
NMFLEBOF_01160 0.0 yhaN L AAA domain
NMFLEBOF_01161 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
NMFLEBOF_01162 1.6e-21 yhaL S Sporulation protein YhaL
NMFLEBOF_01163 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NMFLEBOF_01164 1.5e-89 yhaK S Putative zincin peptidase
NMFLEBOF_01165 2.2e-54 yhaI S Protein of unknown function (DUF1878)
NMFLEBOF_01166 1e-113 hpr K Negative regulator of protease production and sporulation
NMFLEBOF_01167 7e-39 yhaH S YtxH-like protein
NMFLEBOF_01168 5.3e-79 trpP S Tryptophan transporter TrpP
NMFLEBOF_01169 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NMFLEBOF_01170 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
NMFLEBOF_01171 4.6e-137 ecsA V transporter (ATP-binding protein)
NMFLEBOF_01172 4.5e-214 ecsB U ABC transporter
NMFLEBOF_01173 6.9e-114 ecsC S EcsC protein family
NMFLEBOF_01174 8.3e-229 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
NMFLEBOF_01175 7.4e-245 yhfA C membrane
NMFLEBOF_01176 1.6e-33 1.15.1.2 C Rubrerythrin
NMFLEBOF_01177 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
NMFLEBOF_01178 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMFLEBOF_01179 4.5e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NMFLEBOF_01180 5.2e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
NMFLEBOF_01181 4.5e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
NMFLEBOF_01182 4.6e-100 yhgD K Transcriptional regulator
NMFLEBOF_01183 5.1e-214 yhgE S YhgE Pip N-terminal domain protein
NMFLEBOF_01185 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01186 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMFLEBOF_01187 1.4e-136 yhfC S Putative membrane peptidase family (DUF2324)
NMFLEBOF_01189 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
NMFLEBOF_01190 4.1e-71 3.4.13.21 S ASCH
NMFLEBOF_01191 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
NMFLEBOF_01192 1.3e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
NMFLEBOF_01193 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
NMFLEBOF_01194 1.9e-110 yhfK GM NmrA-like family
NMFLEBOF_01195 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMFLEBOF_01196 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01197 1.4e-63 yhfM
NMFLEBOF_01198 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
NMFLEBOF_01199 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
NMFLEBOF_01200 4.7e-76 VY92_01935 K acetyltransferase
NMFLEBOF_01201 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
NMFLEBOF_01202 2.1e-158 yfmC M Periplasmic binding protein
NMFLEBOF_01203 1.5e-134 L Integrase core domain
NMFLEBOF_01204 6e-44 tnpIS3 L Transposase
NMFLEBOF_01205 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
NMFLEBOF_01206 2.2e-196 vraB 2.3.1.9 I Belongs to the thiolase family
NMFLEBOF_01207 2e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
NMFLEBOF_01208 5e-91 bioY S BioY family
NMFLEBOF_01209 2.4e-181 hemAT NT chemotaxis protein
NMFLEBOF_01210 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NMFLEBOF_01211 6e-120 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NMFLEBOF_01212 8.3e-30 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
NMFLEBOF_01213 2.3e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_01214 1.3e-32 yhzC S IDEAL
NMFLEBOF_01215 4.2e-109 comK K Competence transcription factor
NMFLEBOF_01216 2.1e-163 IQ Enoyl-(Acyl carrier protein) reductase
NMFLEBOF_01217 2.8e-39 yhjA S Excalibur calcium-binding domain
NMFLEBOF_01218 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMFLEBOF_01219 6.7e-60 yhjD
NMFLEBOF_01220 5.9e-109 yhjE S SNARE associated Golgi protein
NMFLEBOF_01221 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
NMFLEBOF_01222 2.6e-236 yhjG CH FAD binding domain
NMFLEBOF_01223 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
NMFLEBOF_01224 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01227 4.2e-212 glcP G Major Facilitator Superfamily
NMFLEBOF_01228 1.2e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
NMFLEBOF_01229 2e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
NMFLEBOF_01230 1e-251 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
NMFLEBOF_01231 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
NMFLEBOF_01232 7.1e-201 abrB S membrane
NMFLEBOF_01233 2.1e-211 EGP Transmembrane secretion effector
NMFLEBOF_01234 0.0 S Sugar transport-related sRNA regulator N-term
NMFLEBOF_01235 9.3e-77 yhjR S Rubrerythrin
NMFLEBOF_01236 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
NMFLEBOF_01237 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NMFLEBOF_01238 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
NMFLEBOF_01239 0.0 sbcC L COG0419 ATPase involved in DNA repair
NMFLEBOF_01240 3e-50 yisB V COG1403 Restriction endonuclease
NMFLEBOF_01241 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
NMFLEBOF_01242 3e-66 gerPE S Spore germination protein GerPE
NMFLEBOF_01243 1.1e-23 gerPD S Spore germination protein
NMFLEBOF_01244 5.3e-54 gerPC S Spore germination protein
NMFLEBOF_01245 8.8e-34 gerPB S cell differentiation
NMFLEBOF_01246 5.4e-33 gerPA S Spore germination protein
NMFLEBOF_01247 1.5e-22 yisI S Spo0E like sporulation regulatory protein
NMFLEBOF_01248 9.1e-175 cotH M Spore Coat
NMFLEBOF_01249 1.6e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
NMFLEBOF_01250 3e-57 yisL S UPF0344 protein
NMFLEBOF_01251 0.0 wprA O Belongs to the peptidase S8 family
NMFLEBOF_01253 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01254 1.5e-100 yisN S Protein of unknown function (DUF2777)
NMFLEBOF_01255 0.0 asnO 6.3.5.4 E Asparagine synthase
NMFLEBOF_01256 1.6e-111 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
NMFLEBOF_01257 5.7e-242 yisQ V Mate efflux family protein
NMFLEBOF_01258 1.2e-160 yisR K Transcriptional regulator
NMFLEBOF_01259 5.8e-183 purR K helix_turn _helix lactose operon repressor
NMFLEBOF_01260 1.9e-189 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
NMFLEBOF_01261 7e-92 yisT S DinB family
NMFLEBOF_01262 2.7e-106 argO S Lysine exporter protein LysE YggA
NMFLEBOF_01263 2.4e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
NMFLEBOF_01264 2e-35 mcbG S Pentapeptide repeats (9 copies)
NMFLEBOF_01265 1.3e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMFLEBOF_01266 4e-75 yitH K Acetyltransferase (GNAT) domain
NMFLEBOF_01267 1e-70 yjcF S Acetyltransferase (GNAT) domain
NMFLEBOF_01268 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
NMFLEBOF_01269 5.6e-54 yajQ S Belongs to the UPF0234 family
NMFLEBOF_01270 2e-160 cvfB S protein conserved in bacteria
NMFLEBOF_01271 3.2e-93
NMFLEBOF_01272 2.8e-171
NMFLEBOF_01273 1.5e-97 S Sporulation delaying protein SdpA
NMFLEBOF_01274 4.5e-58 K Transcriptional regulator PadR-like family
NMFLEBOF_01275 4.7e-92
NMFLEBOF_01276 1.4e-44 yitR S Domain of unknown function (DUF3784)
NMFLEBOF_01277 5.5e-308 nprB 3.4.24.28 E Peptidase M4
NMFLEBOF_01278 8.7e-156 yitS S protein conserved in bacteria
NMFLEBOF_01279 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
NMFLEBOF_01280 5e-73 ipi S Intracellular proteinase inhibitor
NMFLEBOF_01281 1.2e-17 S Protein of unknown function (DUF3813)
NMFLEBOF_01283 1.3e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
NMFLEBOF_01284 1.1e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
NMFLEBOF_01285 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
NMFLEBOF_01286 1.5e-22 pilT S Proteolipid membrane potential modulator
NMFLEBOF_01287 1.1e-267 yitY C D-arabinono-1,4-lactone oxidase
NMFLEBOF_01288 5.8e-53 norB G Major Facilitator Superfamily
NMFLEBOF_01289 1e-28 norB G Major Facilitator Superfamily
NMFLEBOF_01290 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NMFLEBOF_01291 9.4e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NMFLEBOF_01292 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
NMFLEBOF_01293 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
NMFLEBOF_01294 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMFLEBOF_01295 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
NMFLEBOF_01296 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NMFLEBOF_01297 2.1e-143 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_01298 1.4e-45 L transposase activity
NMFLEBOF_01299 9.5e-28 yjzC S YjzC-like protein
NMFLEBOF_01300 2.3e-16 yjzD S Protein of unknown function (DUF2929)
NMFLEBOF_01301 6.8e-141 yjaU I carboxylic ester hydrolase activity
NMFLEBOF_01302 1.8e-101 yjaV
NMFLEBOF_01303 3.2e-183 med S Transcriptional activator protein med
NMFLEBOF_01304 4.7e-25 comZ S ComZ
NMFLEBOF_01305 2.7e-22 yjzB
NMFLEBOF_01306 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NMFLEBOF_01307 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NMFLEBOF_01308 7.8e-151 yjaZ O Zn-dependent protease
NMFLEBOF_01309 1.8e-184 appD P Belongs to the ABC transporter superfamily
NMFLEBOF_01310 3.6e-185 appF E Belongs to the ABC transporter superfamily
NMFLEBOF_01311 6.8e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
NMFLEBOF_01312 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01313 3e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01314 5e-147 yjbA S Belongs to the UPF0736 family
NMFLEBOF_01315 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
NMFLEBOF_01316 0.0 oppA E ABC transporter substrate-binding protein
NMFLEBOF_01317 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01318 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01319 6.8e-198 oppD P Belongs to the ABC transporter superfamily
NMFLEBOF_01320 5.5e-172 oppF E Belongs to the ABC transporter superfamily
NMFLEBOF_01321 9.8e-212 yjbB EGP Major Facilitator Superfamily
NMFLEBOF_01322 2.6e-42 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_01323 5.3e-50 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_01324 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NMFLEBOF_01325 1.7e-111 yjbE P Integral membrane protein TerC family
NMFLEBOF_01326 1.2e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMFLEBOF_01327 2.6e-219 yjbF S Competence protein
NMFLEBOF_01328 0.0 pepF E oligoendopeptidase F
NMFLEBOF_01329 1.8e-20
NMFLEBOF_01330 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMFLEBOF_01331 3.7e-72 yjbI S Bacterial-like globin
NMFLEBOF_01332 3.5e-68 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMFLEBOF_01333 1e-99 yjbK S protein conserved in bacteria
NMFLEBOF_01334 7.8e-61 yjbL S Belongs to the UPF0738 family
NMFLEBOF_01335 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
NMFLEBOF_01336 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMFLEBOF_01337 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMFLEBOF_01338 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
NMFLEBOF_01339 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NMFLEBOF_01340 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NMFLEBOF_01341 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
NMFLEBOF_01342 3.7e-215 thiO 1.4.3.19 E Glycine oxidase
NMFLEBOF_01343 4.4e-29 thiS H thiamine diphosphate biosynthetic process
NMFLEBOF_01344 6.5e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
NMFLEBOF_01345 3.7e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMFLEBOF_01346 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMFLEBOF_01347 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NMFLEBOF_01348 7.2e-52 yjbX S Spore coat protein
NMFLEBOF_01349 4.4e-82 cotZ S Spore coat protein
NMFLEBOF_01350 1.1e-34 cotY S Spore coat protein Z
NMFLEBOF_01351 1.4e-38 cotX S Spore Coat Protein X and V domain
NMFLEBOF_01352 1.4e-10 cotW
NMFLEBOF_01353 1.4e-23 cotV S Spore Coat Protein X and V domain
NMFLEBOF_01354 1.9e-56 yjcA S Protein of unknown function (DUF1360)
NMFLEBOF_01357 4.9e-38 spoVIF S Stage VI sporulation protein F
NMFLEBOF_01358 0.0 yjcD 3.6.4.12 L DNA helicase
NMFLEBOF_01359 1.7e-38
NMFLEBOF_01360 8.7e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_01361 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
NMFLEBOF_01362 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
NMFLEBOF_01363 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMFLEBOF_01364 8.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMFLEBOF_01365 1e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
NMFLEBOF_01366 1.7e-210 yjcL S Protein of unknown function (DUF819)
NMFLEBOF_01368 2.9e-25 L Belongs to the 'phage' integrase family
NMFLEBOF_01369 1e-18 L Belongs to the 'phage' integrase family
NMFLEBOF_01370 1e-33 xkdA E IrrE N-terminal-like domain
NMFLEBOF_01372 2.6e-29 S Protein of unknown function (DUF4064)
NMFLEBOF_01373 2e-49
NMFLEBOF_01374 3.6e-45 xre K Helix-turn-helix XRE-family like proteins
NMFLEBOF_01375 3.7e-15 K Helix-turn-helix XRE-family like proteins
NMFLEBOF_01376 1.4e-07 S Helix-turn-helix domain
NMFLEBOF_01377 9.1e-87
NMFLEBOF_01378 3.2e-45 L transposase activity
NMFLEBOF_01379 3.4e-143 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_01380 4.2e-76 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
NMFLEBOF_01381 1.7e-07 K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_01382 1.5e-26 K Helix-turn-helix domain
NMFLEBOF_01383 2.7e-09 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMFLEBOF_01384 2.3e-30
NMFLEBOF_01385 3.9e-47 S Restriction endonuclease
NMFLEBOF_01386 8.9e-126 ynaC
NMFLEBOF_01387 9.5e-51 S Protein of unknown function (DUF1433)
NMFLEBOF_01388 1.3e-241 I Pfam Lipase (class 3)
NMFLEBOF_01389 6.7e-16
NMFLEBOF_01392 1.4e-15 K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_01397 5.2e-07
NMFLEBOF_01400 6.7e-49 S response regulator aspartate phosphatase
NMFLEBOF_01401 2.1e-45 yjcS S Antibiotic biosynthesis monooxygenase
NMFLEBOF_01402 4.9e-43 yjcN
NMFLEBOF_01403 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
NMFLEBOF_01404 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
NMFLEBOF_01405 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
NMFLEBOF_01406 8.7e-48 yjdF S Protein of unknown function (DUF2992)
NMFLEBOF_01407 1.7e-213 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_01408 6.9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
NMFLEBOF_01410 2.6e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NMFLEBOF_01411 4.2e-29 S Domain of unknown function (DUF4177)
NMFLEBOF_01412 2.3e-51 yjdJ S Domain of unknown function (DUF4306)
NMFLEBOF_01413 2.1e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMFLEBOF_01415 1e-262 xynD 3.5.1.104 G Polysaccharide deacetylase
NMFLEBOF_01416 2.1e-82 S Protein of unknown function (DUF2690)
NMFLEBOF_01417 2.3e-20 yjfB S Putative motility protein
NMFLEBOF_01418 5.9e-49 yjfC O Predicted Zn-dependent protease (DUF2268)
NMFLEBOF_01419 1e-107 yjfC O Predicted Zn-dependent protease (DUF2268)
NMFLEBOF_01420 3e-68 T PhoQ Sensor
NMFLEBOF_01421 9.9e-103 yjgB S Domain of unknown function (DUF4309)
NMFLEBOF_01422 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMFLEBOF_01423 1.9e-87 yjgD S Protein of unknown function (DUF1641)
NMFLEBOF_01425 8.7e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
NMFLEBOF_01427 7.3e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
NMFLEBOF_01428 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
NMFLEBOF_01429 8.2e-30
NMFLEBOF_01430 4.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMFLEBOF_01431 7.1e-09 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01432 4.8e-87 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01433 2.5e-85 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01435 1.9e-122 ybbM S transport system, permease component
NMFLEBOF_01436 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
NMFLEBOF_01437 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
NMFLEBOF_01438 4.5e-15 yjlB S Cupin domain
NMFLEBOF_01439 4.9e-41 yjlB S Cupin domain
NMFLEBOF_01440 7.1e-66 yjlC S Protein of unknown function (DUF1641)
NMFLEBOF_01441 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
NMFLEBOF_01442 1.3e-276 uxaC 5.3.1.12 G glucuronate isomerase
NMFLEBOF_01443 1.7e-131 yjmB G symporter YjmB
NMFLEBOF_01444 6.3e-103 yjmB G symporter YjmB
NMFLEBOF_01445 1.4e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
NMFLEBOF_01446 9.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
NMFLEBOF_01447 1.7e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
NMFLEBOF_01448 7.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_01449 2.4e-226 exuT G Sugar (and other) transporter
NMFLEBOF_01450 1.2e-183 exuR K transcriptional
NMFLEBOF_01451 6.4e-284 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
NMFLEBOF_01452 6.6e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
NMFLEBOF_01453 7.4e-130 MA20_18170 S membrane transporter protein
NMFLEBOF_01454 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01456 2.3e-78 yjoA S DinB family
NMFLEBOF_01457 6.6e-212 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
NMFLEBOF_01458 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_01459 1.4e-45 L transposase activity
NMFLEBOF_01460 1e-212 S response regulator aspartate phosphatase
NMFLEBOF_01462 4e-25 S YCII-related domain
NMFLEBOF_01463 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
NMFLEBOF_01464 6.1e-61 yjqA S Bacterial PH domain
NMFLEBOF_01465 1.3e-108 yjqB S Pfam:DUF867
NMFLEBOF_01466 4.4e-160 ydbD P Catalase
NMFLEBOF_01467 1.6e-111 xkdA E IrrE N-terminal-like domain
NMFLEBOF_01468 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
NMFLEBOF_01470 1.9e-155 xkdB K sequence-specific DNA binding
NMFLEBOF_01471 2.4e-118 xkdC L Bacterial dnaA protein
NMFLEBOF_01475 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
NMFLEBOF_01476 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
NMFLEBOF_01477 4.8e-140 xtmA L phage terminase small subunit
NMFLEBOF_01478 1.2e-252 xtmB S phage terminase, large subunit
NMFLEBOF_01479 1.6e-285 yqbA S portal protein
NMFLEBOF_01480 1.7e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
NMFLEBOF_01481 5.8e-169 xkdG S Phage capsid family
NMFLEBOF_01482 5.6e-62 yqbG S Protein of unknown function (DUF3199)
NMFLEBOF_01483 8.7e-65 yqbH S Domain of unknown function (DUF3599)
NMFLEBOF_01484 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
NMFLEBOF_01485 1.9e-77 xkdJ
NMFLEBOF_01486 1.6e-255 xkdK S Phage tail sheath C-terminal domain
NMFLEBOF_01487 1.4e-75 xkdM S Phage tail tube protein
NMFLEBOF_01488 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
NMFLEBOF_01489 1.4e-261 xkdO L Transglycosylase SLT domain
NMFLEBOF_01490 2.3e-117 xkdP S Lysin motif
NMFLEBOF_01491 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
NMFLEBOF_01492 2.1e-39 xkdR S Protein of unknown function (DUF2577)
NMFLEBOF_01493 3.1e-69 xkdS S Protein of unknown function (DUF2634)
NMFLEBOF_01494 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NMFLEBOF_01495 2.6e-100 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
NMFLEBOF_01496 6.7e-41
NMFLEBOF_01497 0.0
NMFLEBOF_01498 2.3e-51 xkdW S XkdW protein
NMFLEBOF_01499 5.5e-22 xkdX
NMFLEBOF_01500 3.4e-152 xepA
NMFLEBOF_01501 1.1e-38 xhlA S Haemolysin XhlA
NMFLEBOF_01502 9.3e-40 xhlB S SPP1 phage holin
NMFLEBOF_01503 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_01504 6.7e-23 spoIISB S Stage II sporulation protein SB
NMFLEBOF_01505 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
NMFLEBOF_01506 7.6e-175 pit P phosphate transporter
NMFLEBOF_01507 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
NMFLEBOF_01508 6.8e-240 steT E amino acid
NMFLEBOF_01509 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
NMFLEBOF_01510 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMFLEBOF_01511 3.2e-178 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMFLEBOF_01513 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMFLEBOF_01514 1.6e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
NMFLEBOF_01515 5.1e-153 dppA E D-aminopeptidase
NMFLEBOF_01516 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01517 8.1e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
NMFLEBOF_01518 5.6e-186 dppD P Belongs to the ABC transporter superfamily
NMFLEBOF_01519 0.0 dppE E ABC transporter substrate-binding protein
NMFLEBOF_01521 2.1e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
NMFLEBOF_01522 3.8e-196 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
NMFLEBOF_01523 8.5e-162 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMFLEBOF_01524 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
NMFLEBOF_01525 3.6e-204 pgl 3.1.1.31 G 6-phosphogluconolactonase
NMFLEBOF_01526 3.3e-80 ykgA E Amidinotransferase
NMFLEBOF_01527 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
NMFLEBOF_01528 1.2e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NMFLEBOF_01529 1.5e-09
NMFLEBOF_01530 8.6e-128 ykjA S Protein of unknown function (DUF421)
NMFLEBOF_01531 2.2e-96 ykkA S Protein of unknown function (DUF664)
NMFLEBOF_01532 1.6e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMFLEBOF_01533 2.9e-54 ykkC P Multidrug resistance protein
NMFLEBOF_01534 1.6e-25 ykkD P Multidrug resistance protein
NMFLEBOF_01535 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
NMFLEBOF_01536 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMFLEBOF_01537 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NMFLEBOF_01538 1.3e-70 ohrA O Organic hydroperoxide resistance protein
NMFLEBOF_01539 4.8e-73 ohrR K COG1846 Transcriptional regulators
NMFLEBOF_01540 2.4e-71 ohrB O Organic hydroperoxide resistance protein
NMFLEBOF_01541 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
NMFLEBOF_01542 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NMFLEBOF_01543 1.5e-175 isp O Belongs to the peptidase S8 family
NMFLEBOF_01544 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMFLEBOF_01545 7.6e-135 ykoC P Cobalt transport protein
NMFLEBOF_01546 7.5e-305 P ABC transporter, ATP-binding protein
NMFLEBOF_01547 1.5e-98 ykoE S ABC-type cobalt transport system, permease component
NMFLEBOF_01548 5.7e-109 ykoF S YKOF-related Family
NMFLEBOF_01549 3.3e-121 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_01550 2.8e-241 ykoH 2.7.13.3 T Histidine kinase
NMFLEBOF_01551 1.2e-112 ykoI S Peptidase propeptide and YPEB domain
NMFLEBOF_01552 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
NMFLEBOF_01555 2.2e-222 mgtE P Acts as a magnesium transporter
NMFLEBOF_01556 1.4e-53 tnrA K transcriptional
NMFLEBOF_01557 5.9e-18
NMFLEBOF_01558 6.9e-26 ykoL
NMFLEBOF_01559 1.3e-81 mhqR K transcriptional
NMFLEBOF_01560 2e-216 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
NMFLEBOF_01561 1.1e-93 ykoP G polysaccharide deacetylase
NMFLEBOF_01562 6.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
NMFLEBOF_01563 0.0 ykoS
NMFLEBOF_01564 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMFLEBOF_01565 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
NMFLEBOF_01566 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
NMFLEBOF_01567 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
NMFLEBOF_01568 3.5e-109 ykoX S membrane-associated protein
NMFLEBOF_01569 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
NMFLEBOF_01570 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_01571 5.9e-107 rsgI S Anti-sigma factor N-terminus
NMFLEBOF_01572 1.9e-26 sspD S small acid-soluble spore protein
NMFLEBOF_01573 1.5e-124 ykrK S Domain of unknown function (DUF1836)
NMFLEBOF_01574 3.5e-155 htpX O Belongs to the peptidase M48B family
NMFLEBOF_01575 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
NMFLEBOF_01576 1.2e-10 ydfR S Protein of unknown function (DUF421)
NMFLEBOF_01577 2.2e-21 ykzE
NMFLEBOF_01578 1.1e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
NMFLEBOF_01579 0.0 kinE 2.7.13.3 T Histidine kinase
NMFLEBOF_01580 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NMFLEBOF_01582 2.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NMFLEBOF_01583 1.7e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
NMFLEBOF_01584 4.2e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
NMFLEBOF_01585 1.1e-231 mtnE 2.6.1.83 E Aminotransferase
NMFLEBOF_01586 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
NMFLEBOF_01587 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
NMFLEBOF_01588 5.2e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
NMFLEBOF_01589 4.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
NMFLEBOF_01590 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
NMFLEBOF_01591 2.2e-09 S Spo0E like sporulation regulatory protein
NMFLEBOF_01592 3.7e-52 eag
NMFLEBOF_01593 2.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMFLEBOF_01594 1.3e-75 ykvE K transcriptional
NMFLEBOF_01595 2e-122 motB N Flagellar motor protein
NMFLEBOF_01596 5.1e-137 motA N flagellar motor
NMFLEBOF_01597 0.0 clpE O Belongs to the ClpA ClpB family
NMFLEBOF_01598 1.6e-180 ykvI S membrane
NMFLEBOF_01599 6.2e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NMFLEBOF_01600 3.7e-81 queD 4.1.2.50, 4.2.3.12 H synthase
NMFLEBOF_01601 1.9e-138 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NMFLEBOF_01602 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NMFLEBOF_01603 8.1e-45 ykvR S Protein of unknown function (DUF3219)
NMFLEBOF_01604 6e-25 ykvS S protein conserved in bacteria
NMFLEBOF_01605 2.8e-28
NMFLEBOF_01606 3.5e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
NMFLEBOF_01607 6.4e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_01608 1.6e-88 stoA CO thiol-disulfide
NMFLEBOF_01609 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMFLEBOF_01610 8.2e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMFLEBOF_01611 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
NMFLEBOF_01612 2.9e-127 glcT K antiterminator
NMFLEBOF_01613 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_01614 2.1e-39 ptsH G phosphocarrier protein HPr
NMFLEBOF_01615 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NMFLEBOF_01616 7.2e-39 splA S Transcriptional regulator
NMFLEBOF_01617 1.4e-200 splB 4.1.99.14 L Spore photoproduct lyase
NMFLEBOF_01618 7.8e-126 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_01619 7.2e-254 mcpC NT chemotaxis protein
NMFLEBOF_01620 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
NMFLEBOF_01621 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01623 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_01624 2.9e-107 ykwD J protein with SCP PR1 domains
NMFLEBOF_01625 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
NMFLEBOF_01626 0.0 pilS 2.7.13.3 T Histidine kinase
NMFLEBOF_01627 8.8e-223 patA 2.6.1.1 E Aminotransferase
NMFLEBOF_01628 2.2e-15
NMFLEBOF_01629 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
NMFLEBOF_01630 1.7e-84 ykyB S YkyB-like protein
NMFLEBOF_01631 2.8e-238 ykuC EGP Major facilitator Superfamily
NMFLEBOF_01632 1.8e-87 ykuD S protein conserved in bacteria
NMFLEBOF_01633 2.7e-165 ykuE S Metallophosphoesterase
NMFLEBOF_01634 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_01635 5.2e-234 ykuI T Diguanylate phosphodiesterase
NMFLEBOF_01636 3.9e-37 ykuJ S protein conserved in bacteria
NMFLEBOF_01637 4.4e-94 ykuK S Ribonuclease H-like
NMFLEBOF_01638 3.9e-27 ykzF S Antirepressor AbbA
NMFLEBOF_01639 1.8e-75 ykuL S CBS domain
NMFLEBOF_01640 1.8e-167 ccpC K Transcriptional regulator
NMFLEBOF_01641 3.7e-87 fld C Flavodoxin domain
NMFLEBOF_01642 1.5e-174 ykuO
NMFLEBOF_01643 8.7e-78 fld C Flavodoxin
NMFLEBOF_01644 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NMFLEBOF_01645 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NMFLEBOF_01646 9e-37 ykuS S Belongs to the UPF0180 family
NMFLEBOF_01647 8.8e-142 ykuT M Mechanosensitive ion channel
NMFLEBOF_01648 3.9e-101 ykuU O Alkyl hydroperoxide reductase
NMFLEBOF_01649 1.4e-80 ykuV CO thiol-disulfide
NMFLEBOF_01650 5.8e-95 rok K Repressor of ComK
NMFLEBOF_01651 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_01652 3.2e-45 L transposase activity
NMFLEBOF_01653 1e-144 yknT
NMFLEBOF_01654 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
NMFLEBOF_01655 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
NMFLEBOF_01656 1.2e-244 moeA 2.10.1.1 H molybdopterin
NMFLEBOF_01657 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
NMFLEBOF_01658 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
NMFLEBOF_01659 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NMFLEBOF_01660 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMFLEBOF_01661 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
NMFLEBOF_01662 2.9e-117 yknW S Yip1 domain
NMFLEBOF_01663 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NMFLEBOF_01664 9.4e-124 macB V ABC transporter, ATP-binding protein
NMFLEBOF_01665 6.2e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMFLEBOF_01666 7.5e-135 fruR K Transcriptional regulator
NMFLEBOF_01667 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
NMFLEBOF_01668 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
NMFLEBOF_01669 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMFLEBOF_01670 8.1e-39 ykoA
NMFLEBOF_01671 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
NMFLEBOF_01672 9e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMFLEBOF_01673 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01674 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
NMFLEBOF_01675 1.1e-12 S Uncharacterized protein YkpC
NMFLEBOF_01676 7.7e-183 mreB D Rod-share determining protein MreBH
NMFLEBOF_01677 1.5e-43 abrB K of stationary sporulation gene expression
NMFLEBOF_01678 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
NMFLEBOF_01679 6.8e-161 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
NMFLEBOF_01680 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
NMFLEBOF_01681 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NMFLEBOF_01682 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMFLEBOF_01683 8.2e-31 ykzG S Belongs to the UPF0356 family
NMFLEBOF_01684 4.2e-147 ykrA S hydrolases of the HAD superfamily
NMFLEBOF_01685 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMFLEBOF_01687 2e-115 recN L Putative cell-wall binding lipoprotein
NMFLEBOF_01688 2.2e-191 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMFLEBOF_01689 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMFLEBOF_01690 2.2e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMFLEBOF_01691 1.6e-242 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMFLEBOF_01692 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
NMFLEBOF_01693 8.1e-10 S SR1 protein
NMFLEBOF_01694 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01695 1e-276 speA 4.1.1.19 E Arginine
NMFLEBOF_01696 1.7e-41 yktA S Belongs to the UPF0223 family
NMFLEBOF_01697 4.6e-117 yktB S Belongs to the UPF0637 family
NMFLEBOF_01698 7.1e-26 ykzI
NMFLEBOF_01699 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
NMFLEBOF_01700 3.8e-76 ykzC S Acetyltransferase (GNAT) family
NMFLEBOF_01701 4.6e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
NMFLEBOF_01702 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
NMFLEBOF_01703 0.0 ylaA
NMFLEBOF_01704 2.7e-42 ylaB
NMFLEBOF_01705 8e-39 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_01706 1.6e-11 sigC S Putative zinc-finger
NMFLEBOF_01707 1.8e-38 ylaE
NMFLEBOF_01708 8.2e-22 S Family of unknown function (DUF5325)
NMFLEBOF_01709 0.0 typA T GTP-binding protein TypA
NMFLEBOF_01710 4.2e-47 ylaH S YlaH-like protein
NMFLEBOF_01711 2.5e-32 ylaI S protein conserved in bacteria
NMFLEBOF_01712 3.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMFLEBOF_01713 1.8e-248 phoH T ATPase related to phosphate starvation-inducible protein PhoH
NMFLEBOF_01714 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NMFLEBOF_01715 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
NMFLEBOF_01716 8.7e-44 ylaN S Belongs to the UPF0358 family
NMFLEBOF_01717 3.6e-211 ftsW D Belongs to the SEDS family
NMFLEBOF_01718 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
NMFLEBOF_01720 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01721 9.4e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
NMFLEBOF_01722 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
NMFLEBOF_01723 5.2e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NMFLEBOF_01724 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMFLEBOF_01725 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
NMFLEBOF_01726 1.2e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
NMFLEBOF_01727 7e-164 ctaG S cytochrome c oxidase
NMFLEBOF_01728 7e-62 ylbA S YugN-like family
NMFLEBOF_01729 4.4e-74 ylbB T COG0517 FOG CBS domain
NMFLEBOF_01730 9.6e-200 ylbC S protein with SCP PR1 domains
NMFLEBOF_01731 2e-62 ylbD S Putative coat protein
NMFLEBOF_01732 6.7e-37 ylbE S YlbE-like protein
NMFLEBOF_01733 1.8e-75 ylbF S Belongs to the UPF0342 family
NMFLEBOF_01734 7.5e-39 ylbG S UPF0298 protein
NMFLEBOF_01735 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
NMFLEBOF_01736 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NMFLEBOF_01737 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
NMFLEBOF_01738 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
NMFLEBOF_01739 6.8e-187 ylbL T Belongs to the peptidase S16 family
NMFLEBOF_01740 4.3e-228 ylbM S Belongs to the UPF0348 family
NMFLEBOF_01742 2.5e-89 yceD S metal-binding, possibly nucleic acid-binding protein
NMFLEBOF_01743 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NMFLEBOF_01744 7.5e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
NMFLEBOF_01745 1.5e-88 ylbP K n-acetyltransferase
NMFLEBOF_01746 1.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NMFLEBOF_01747 5.1e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
NMFLEBOF_01748 2.9e-78 mraZ K Belongs to the MraZ family
NMFLEBOF_01749 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NMFLEBOF_01750 3.7e-44 ftsL D Essential cell division protein
NMFLEBOF_01751 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NMFLEBOF_01752 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
NMFLEBOF_01753 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NMFLEBOF_01754 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NMFLEBOF_01755 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NMFLEBOF_01756 5.7e-186 spoVE D Belongs to the SEDS family
NMFLEBOF_01757 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NMFLEBOF_01758 5.3e-167 murB 1.3.1.98 M cell wall formation
NMFLEBOF_01759 2.2e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NMFLEBOF_01760 2.4e-103 ylxW S protein conserved in bacteria
NMFLEBOF_01761 5.1e-102 ylxX S protein conserved in bacteria
NMFLEBOF_01762 6.2e-58 sbp S small basic protein
NMFLEBOF_01763 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NMFLEBOF_01764 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NMFLEBOF_01765 0.0 bpr O COG1404 Subtilisin-like serine proteases
NMFLEBOF_01767 6.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
NMFLEBOF_01768 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_01769 1.4e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_01770 9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
NMFLEBOF_01771 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
NMFLEBOF_01772 2.4e-37 ylmC S sporulation protein
NMFLEBOF_01773 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
NMFLEBOF_01774 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NMFLEBOF_01775 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NMFLEBOF_01776 1.6e-39 yggT S membrane
NMFLEBOF_01777 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
NMFLEBOF_01778 2.6e-67 divIVA D Cell division initiation protein
NMFLEBOF_01779 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NMFLEBOF_01780 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01782 3.8e-63 dksA T COG1734 DnaK suppressor protein
NMFLEBOF_01783 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NMFLEBOF_01784 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NMFLEBOF_01785 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NMFLEBOF_01786 1.5e-231 pyrP F Xanthine uracil
NMFLEBOF_01787 2.6e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NMFLEBOF_01788 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NMFLEBOF_01789 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NMFLEBOF_01790 0.0 carB 6.3.5.5 F Belongs to the CarB family
NMFLEBOF_01791 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
NMFLEBOF_01792 6.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NMFLEBOF_01793 2.3e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NMFLEBOF_01794 8e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NMFLEBOF_01795 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
NMFLEBOF_01796 1.8e-179 cysP P phosphate transporter
NMFLEBOF_01797 5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
NMFLEBOF_01798 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
NMFLEBOF_01799 8.8e-48 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMFLEBOF_01800 7e-43 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
NMFLEBOF_01801 4.9e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
NMFLEBOF_01802 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
NMFLEBOF_01803 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
NMFLEBOF_01804 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
NMFLEBOF_01805 2.4e-156 yloC S stress-induced protein
NMFLEBOF_01806 1.5e-40 ylzA S Belongs to the UPF0296 family
NMFLEBOF_01807 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
NMFLEBOF_01808 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NMFLEBOF_01809 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NMFLEBOF_01810 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NMFLEBOF_01811 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NMFLEBOF_01812 2.6e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NMFLEBOF_01813 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NMFLEBOF_01814 1e-204 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
NMFLEBOF_01815 1.1e-138 stp 3.1.3.16 T phosphatase
NMFLEBOF_01816 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NMFLEBOF_01817 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NMFLEBOF_01818 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NMFLEBOF_01819 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
NMFLEBOF_01820 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NMFLEBOF_01821 5.5e-59 asp S protein conserved in bacteria
NMFLEBOF_01822 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
NMFLEBOF_01823 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
NMFLEBOF_01824 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
NMFLEBOF_01825 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NMFLEBOF_01826 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
NMFLEBOF_01827 9.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NMFLEBOF_01828 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
NMFLEBOF_01829 2.3e-128 IQ reductase
NMFLEBOF_01830 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NMFLEBOF_01831 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NMFLEBOF_01832 0.0 smc D Required for chromosome condensation and partitioning
NMFLEBOF_01833 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NMFLEBOF_01834 2.9e-87
NMFLEBOF_01835 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NMFLEBOF_01836 8.7e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NMFLEBOF_01837 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NMFLEBOF_01838 4.5e-36 ylqC S Belongs to the UPF0109 family
NMFLEBOF_01839 6.3e-61 ylqD S YlqD protein
NMFLEBOF_01840 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NMFLEBOF_01841 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NMFLEBOF_01842 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NMFLEBOF_01843 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NMFLEBOF_01844 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMFLEBOF_01845 9.2e-282 ylqG
NMFLEBOF_01846 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
NMFLEBOF_01847 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
NMFLEBOF_01848 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NMFLEBOF_01849 2e-166 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
NMFLEBOF_01850 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NMFLEBOF_01851 1.6e-246 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NMFLEBOF_01852 2.2e-168 xerC L tyrosine recombinase XerC
NMFLEBOF_01853 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NMFLEBOF_01854 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NMFLEBOF_01855 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
NMFLEBOF_01856 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
NMFLEBOF_01857 2e-74 flgC N Belongs to the flagella basal body rod proteins family
NMFLEBOF_01858 1.9e-31 fliE N Flagellar hook-basal body
NMFLEBOF_01859 7.7e-254 fliF N The M ring may be actively involved in energy transduction
NMFLEBOF_01860 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMFLEBOF_01861 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
NMFLEBOF_01862 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
NMFLEBOF_01863 1.5e-69 fliJ N Flagellar biosynthesis chaperone
NMFLEBOF_01864 1.3e-36 ylxF S MgtE intracellular N domain
NMFLEBOF_01865 1.7e-215 fliK N Flagellar hook-length control protein
NMFLEBOF_01866 2.3e-72 flgD N Flagellar basal body rod modification protein
NMFLEBOF_01867 1.8e-139 flgG N Flagellar basal body rod
NMFLEBOF_01868 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
NMFLEBOF_01869 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
NMFLEBOF_01870 9.5e-182 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NMFLEBOF_01871 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
NMFLEBOF_01872 1.5e-91 fliZ N Flagellar biosynthesis protein, FliO
NMFLEBOF_01873 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
NMFLEBOF_01874 2.2e-36 fliQ N Role in flagellar biosynthesis
NMFLEBOF_01875 3.6e-132 fliR N Flagellar biosynthetic protein FliR
NMFLEBOF_01876 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMFLEBOF_01877 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NMFLEBOF_01878 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
NMFLEBOF_01879 6.3e-157 flhG D Belongs to the ParA family
NMFLEBOF_01880 3.7e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
NMFLEBOF_01881 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
NMFLEBOF_01882 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
NMFLEBOF_01883 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
NMFLEBOF_01884 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
NMFLEBOF_01885 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_01886 4.3e-78 ylxL
NMFLEBOF_01887 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
NMFLEBOF_01888 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NMFLEBOF_01889 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NMFLEBOF_01890 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NMFLEBOF_01891 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NMFLEBOF_01892 5.9e-138 cdsA 2.7.7.41 S Belongs to the CDS family
NMFLEBOF_01893 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
NMFLEBOF_01894 7.7e-233 rasP M zinc metalloprotease
NMFLEBOF_01895 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NMFLEBOF_01896 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NMFLEBOF_01897 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
NMFLEBOF_01898 1.1e-203 nusA K Participates in both transcription termination and antitermination
NMFLEBOF_01899 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
NMFLEBOF_01900 3.1e-47 ylxQ J ribosomal protein
NMFLEBOF_01901 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NMFLEBOF_01902 3.9e-44 ylxP S protein conserved in bacteria
NMFLEBOF_01903 2.5e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NMFLEBOF_01904 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NMFLEBOF_01905 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NMFLEBOF_01906 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NMFLEBOF_01907 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
NMFLEBOF_01908 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
NMFLEBOF_01909 4.4e-233 pepR S Belongs to the peptidase M16 family
NMFLEBOF_01910 2.6e-42 ymxH S YlmC YmxH family
NMFLEBOF_01911 8.6e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
NMFLEBOF_01912 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
NMFLEBOF_01913 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NMFLEBOF_01914 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMFLEBOF_01915 4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NMFLEBOF_01916 1.6e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NMFLEBOF_01917 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
NMFLEBOF_01918 4.4e-32 S YlzJ-like protein
NMFLEBOF_01919 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NMFLEBOF_01920 1.4e-133 ymfC K Transcriptional regulator
NMFLEBOF_01921 3.8e-205 ymfD EGP Major facilitator Superfamily
NMFLEBOF_01922 1.2e-233 ymfF S Peptidase M16
NMFLEBOF_01923 1.4e-242 ymfH S zinc protease
NMFLEBOF_01924 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
NMFLEBOF_01925 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
NMFLEBOF_01926 2.7e-143 ymfK S Protein of unknown function (DUF3388)
NMFLEBOF_01927 5.5e-124 ymfM S protein conserved in bacteria
NMFLEBOF_01928 5.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NMFLEBOF_01929 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
NMFLEBOF_01930 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NMFLEBOF_01931 2e-211 pbpX V Beta-lactamase
NMFLEBOF_01932 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
NMFLEBOF_01933 5.5e-152 ymdB S protein conserved in bacteria
NMFLEBOF_01934 1.2e-36 spoVS S Stage V sporulation protein S
NMFLEBOF_01935 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
NMFLEBOF_01936 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMFLEBOF_01937 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_01938 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NMFLEBOF_01939 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
NMFLEBOF_01940 2.2e-88 cotE S Spore coat protein
NMFLEBOF_01941 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NMFLEBOF_01942 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NMFLEBOF_01947 9.4e-23 wecC 1.1.1.336 M ArpU family transcriptional regulator
NMFLEBOF_01948 8.9e-45 L Phage integrase family
NMFLEBOF_01954 5.9e-64 S HNH endonuclease
NMFLEBOF_01955 3.8e-08
NMFLEBOF_01956 4.6e-70 S Phage terminase, small subunit
NMFLEBOF_01957 4.6e-08 S Terminase
NMFLEBOF_01958 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_01959 9.9e-69 S Regulatory protein YrvL
NMFLEBOF_01960 3e-96 ymcC S Membrane
NMFLEBOF_01961 3.3e-104 pksA K Transcriptional regulator
NMFLEBOF_01962 4.4e-61 ymzB
NMFLEBOF_01963 2.8e-162 ymaE S Metallo-beta-lactamase superfamily
NMFLEBOF_01964 4.3e-250 aprX O Belongs to the peptidase S8 family
NMFLEBOF_01965 1.9e-07 K Transcriptional regulator
NMFLEBOF_01966 2.1e-126 ymaC S Replication protein
NMFLEBOF_01967 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
NMFLEBOF_01968 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
NMFLEBOF_01969 1.4e-50 ebrA P Small Multidrug Resistance protein
NMFLEBOF_01971 2.1e-46 ymaF S YmaF family
NMFLEBOF_01972 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NMFLEBOF_01973 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
NMFLEBOF_01974 8.2e-23
NMFLEBOF_01975 4.5e-22 ymzA
NMFLEBOF_01976 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
NMFLEBOF_01977 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMFLEBOF_01978 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NMFLEBOF_01979 2e-109 ymaB
NMFLEBOF_01980 1.5e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_01981 1.7e-176 spoVK O stage V sporulation protein K
NMFLEBOF_01982 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NMFLEBOF_01983 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
NMFLEBOF_01984 1.1e-68 glnR K transcriptional
NMFLEBOF_01985 1e-259 glnA 6.3.1.2 E glutamine synthetase
NMFLEBOF_01986 2.8e-24
NMFLEBOF_01987 2.2e-40
NMFLEBOF_01988 1.6e-247 M nucleic acid phosphodiester bond hydrolysis
NMFLEBOF_01990 1.1e-09
NMFLEBOF_01991 2.7e-32
NMFLEBOF_01992 6.2e-85
NMFLEBOF_01993 3.7e-38
NMFLEBOF_01994 1.5e-89 G SMI1-KNR4 cell-wall
NMFLEBOF_01995 2.5e-40 ynaC
NMFLEBOF_01996 7.6e-63 ynaC
NMFLEBOF_01997 4.2e-236 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_01998 4.1e-11 S Protein of unknown function (DUF1433)
NMFLEBOF_01999 2e-97 ynaD J Acetyltransferase (GNAT) domain
NMFLEBOF_02001 4.7e-75 S CAAX protease self-immunity
NMFLEBOF_02002 4.7e-08 S Uncharacterised protein family (UPF0715)
NMFLEBOF_02003 5.5e-20 K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_02005 3e-79 ynaE S Domain of unknown function (DUF3885)
NMFLEBOF_02006 9.5e-14 ynaF
NMFLEBOF_02007 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
NMFLEBOF_02008 7.9e-255 xynT G MFS/sugar transport protein
NMFLEBOF_02009 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
NMFLEBOF_02010 6.8e-212 xylR GK ROK family
NMFLEBOF_02011 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
NMFLEBOF_02012 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
NMFLEBOF_02013 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_02014 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
NMFLEBOF_02015 1.4e-254 iolT EGP Major facilitator Superfamily
NMFLEBOF_02016 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NMFLEBOF_02018 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
NMFLEBOF_02019 5.2e-15
NMFLEBOF_02022 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NMFLEBOF_02024 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02026 8.9e-128 S Domain of unknown function, YrpD
NMFLEBOF_02029 7.9e-25 tatA U protein secretion
NMFLEBOF_02030 1.8e-71
NMFLEBOF_02031 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
NMFLEBOF_02034 2.8e-52 gerAA EG Spore germination protein
NMFLEBOF_02035 1.8e-146 gerAA EG Spore germination protein
NMFLEBOF_02036 3.4e-88 gerLC S Spore germination protein
NMFLEBOF_02037 7.2e-152 yndG S DoxX-like family
NMFLEBOF_02038 8e-114 yndH S Domain of unknown function (DUF4166)
NMFLEBOF_02039 1.6e-307 yndJ S YndJ-like protein
NMFLEBOF_02042 4.4e-135 yndL S Replication protein
NMFLEBOF_02043 6.4e-73 yndM S Protein of unknown function (DUF2512)
NMFLEBOF_02044 2.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
NMFLEBOF_02045 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NMFLEBOF_02046 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
NMFLEBOF_02047 5e-111 yneB L resolvase
NMFLEBOF_02048 1.3e-32 ynzC S UPF0291 protein
NMFLEBOF_02049 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NMFLEBOF_02050 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
NMFLEBOF_02051 1.8e-28 yneF S UPF0154 protein
NMFLEBOF_02052 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
NMFLEBOF_02053 7.1e-127 ccdA O cytochrome c biogenesis protein
NMFLEBOF_02054 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
NMFLEBOF_02055 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
NMFLEBOF_02056 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_02057 1.4e-45 L transposase activity
NMFLEBOF_02058 4.2e-74 yneK S Protein of unknown function (DUF2621)
NMFLEBOF_02059 1.2e-64 hspX O Spore coat protein
NMFLEBOF_02060 3.9e-19 sspP S Belongs to the SspP family
NMFLEBOF_02061 2.2e-14 sspO S Belongs to the SspO family
NMFLEBOF_02062 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NMFLEBOF_02063 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NMFLEBOF_02065 3.1e-08 sspN S Small acid-soluble spore protein N family
NMFLEBOF_02066 3.9e-35 tlp S Belongs to the Tlp family
NMFLEBOF_02067 2e-73 yneP S Thioesterase-like superfamily
NMFLEBOF_02068 1.7e-53 yneQ
NMFLEBOF_02069 4.1e-49 yneR S Belongs to the HesB IscA family
NMFLEBOF_02070 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NMFLEBOF_02071 8.6e-69 yccU S CoA-binding protein
NMFLEBOF_02072 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMFLEBOF_02073 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NMFLEBOF_02074 2.3e-12
NMFLEBOF_02075 8.6e-57 ynfC
NMFLEBOF_02076 5.3e-251 agcS E Sodium alanine symporter
NMFLEBOF_02077 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
NMFLEBOF_02079 2.5e-177 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NMFLEBOF_02080 1.4e-25 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
NMFLEBOF_02081 1.7e-243 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NMFLEBOF_02082 6.5e-25 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
NMFLEBOF_02083 2.5e-77 yngA S membrane
NMFLEBOF_02084 5e-162 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMFLEBOF_02085 2.1e-103 yngC S membrane-associated protein
NMFLEBOF_02086 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
NMFLEBOF_02087 5e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMFLEBOF_02088 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMFLEBOF_02089 2.2e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
NMFLEBOF_02090 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
NMFLEBOF_02091 1.1e-248 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
NMFLEBOF_02092 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMFLEBOF_02093 4.8e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
NMFLEBOF_02094 5.5e-302 yngK T Glycosyl hydrolase-like 10
NMFLEBOF_02095 3.1e-63 yngL S Protein of unknown function (DUF1360)
NMFLEBOF_02096 1.1e-41 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NMFLEBOF_02097 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
NMFLEBOF_02098 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_02099 4.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
NMFLEBOF_02100 4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
NMFLEBOF_02101 8.7e-246 yoeA V MATE efflux family protein
NMFLEBOF_02102 9.1e-98 yoeB S IseA DL-endopeptidase inhibitor
NMFLEBOF_02104 2.2e-96 L Integrase
NMFLEBOF_02105 3e-34 yoeD G Helix-turn-helix domain
NMFLEBOF_02106 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMFLEBOF_02107 4.7e-157 gltR1 K Transcriptional regulator
NMFLEBOF_02108 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
NMFLEBOF_02109 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
NMFLEBOF_02110 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
NMFLEBOF_02111 7.8e-155 gltC K Transcriptional regulator
NMFLEBOF_02112 1.4e-136 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NMFLEBOF_02113 1.4e-78 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFLEBOF_02114 1e-42 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFLEBOF_02115 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
NMFLEBOF_02116 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_02117 7.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
NMFLEBOF_02118 3.2e-133 yoxB
NMFLEBOF_02119 2e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMFLEBOF_02120 1.5e-127 V ABC-2 family transporter protein
NMFLEBOF_02121 4.9e-94 V ABC-2 family transporter protein
NMFLEBOF_02122 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
NMFLEBOF_02123 3e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
NMFLEBOF_02124 1.1e-234 yoaB EGP Major facilitator Superfamily
NMFLEBOF_02125 2.9e-90 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
NMFLEBOF_02126 2e-97 S Protein of unknown function (DUF421)
NMFLEBOF_02127 2.1e-285 clsA_1 I PLD-like domain
NMFLEBOF_02128 1.2e-70 S Protein of unknown function (DUF421)
NMFLEBOF_02129 2.8e-07 S Protein of unknown function (DUF421)
NMFLEBOF_02130 1.1e-150 yetF1 S membrane
NMFLEBOF_02131 5.8e-29 S Protein of unknown function (DUF1657)
NMFLEBOF_02132 1.5e-56 spoVAE S stage V sporulation protein
NMFLEBOF_02133 1e-195 spoVAD I Stage V sporulation protein AD
NMFLEBOF_02134 5.7e-80 spoVAC S stage V sporulation protein AC
NMFLEBOF_02135 6e-26 S Protein of unknown function (DUF1657)
NMFLEBOF_02136 1.1e-23 cat P Catalase
NMFLEBOF_02137 6.1e-160 cat P Catalase
NMFLEBOF_02138 1.5e-24 S Protein of unknown function (DUF2642)
NMFLEBOF_02139 1.5e-10 S TIGRFAM germination protein, Ger(x)C family
NMFLEBOF_02140 3.3e-154 EG Spore germination protein
NMFLEBOF_02141 8.2e-32 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_02142 1.7e-76
NMFLEBOF_02143 1.8e-20 L Transposase and inactivated derivatives, TnpA family
NMFLEBOF_02144 1.8e-50 L Transposase and inactivated derivatives, TnpA family
NMFLEBOF_02145 9.7e-16 mcpU NT methyl-accepting chemotaxis protein
NMFLEBOF_02146 2.8e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
NMFLEBOF_02147 9.4e-132 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
NMFLEBOF_02148 8.9e-111 yoaK S Membrane
NMFLEBOF_02149 2.2e-52 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NMFLEBOF_02150 9.5e-94 pelB 4.2.2.10, 4.2.2.2 G Amb_all
NMFLEBOF_02151 1.9e-52 yoqW S Belongs to the SOS response-associated peptidase family
NMFLEBOF_02153 2.5e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
NMFLEBOF_02156 4.4e-83
NMFLEBOF_02157 1.1e-169 yoaR V vancomycin resistance protein
NMFLEBOF_02158 7.3e-75 yoaS S Protein of unknown function (DUF2975)
NMFLEBOF_02159 3.9e-29 yozG K Transcriptional regulator
NMFLEBOF_02160 4.1e-147 yoaT S Protein of unknown function (DUF817)
NMFLEBOF_02161 1.1e-158 yoaU K LysR substrate binding domain
NMFLEBOF_02162 2.5e-158 yijE EG EamA-like transporter family
NMFLEBOF_02163 1.6e-76 yoaW
NMFLEBOF_02164 8e-114 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
NMFLEBOF_02165 5.3e-167 bla 3.5.2.6 V beta-lactamase
NMFLEBOF_02168 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
NMFLEBOF_02169 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
NMFLEBOF_02170 8.8e-37 S TM2 domain
NMFLEBOF_02171 1.5e-53 K Helix-turn-helix
NMFLEBOF_02174 4e-30
NMFLEBOF_02176 1.1e-220 L Transposase
NMFLEBOF_02177 9.9e-119 L PhoH-like protein
NMFLEBOF_02180 8.7e-241 flp V Beta-lactamase
NMFLEBOF_02182 3.9e-10 ywlA S Uncharacterised protein family (UPF0715)
NMFLEBOF_02184 2.6e-52 ynaF
NMFLEBOF_02185 9.4e-81 ynaE S Domain of unknown function (DUF3885)
NMFLEBOF_02186 2.3e-07 ynaE S Domain of unknown function (DUF3885)
NMFLEBOF_02187 1.2e-25 K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_02188 6.2e-81 yoaW
NMFLEBOF_02189 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
NMFLEBOF_02190 1.5e-76
NMFLEBOF_02191 4.3e-45 yoaQ S Evidence 4 Homologs of previously reported genes of
NMFLEBOF_02192 1.4e-24 yoqW S Belongs to the SOS response-associated peptidase family
NMFLEBOF_02194 3.1e-87 S response regulator aspartate phosphatase
NMFLEBOF_02196 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
NMFLEBOF_02197 5.7e-22 Q Methyltransferase
NMFLEBOF_02198 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
NMFLEBOF_02199 2e-32 Q Methyltransferase domain
NMFLEBOF_02200 3.7e-23 G Major Facilitator Superfamily
NMFLEBOF_02201 4.2e-236 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_02202 1.1e-30 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMFLEBOF_02203 3.8e-39 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMFLEBOF_02204 6.6e-67 S impB/mucB/samB family C-terminal domain
NMFLEBOF_02205 1.9e-09 S YolD-like protein
NMFLEBOF_02206 1.4e-13
NMFLEBOF_02208 1.8e-98 J Acetyltransferase (GNAT) domain
NMFLEBOF_02209 6e-100 yokK S SMI1 / KNR4 family
NMFLEBOF_02210 8.8e-78 S SMI1-KNR4 cell-wall
NMFLEBOF_02211 6.7e-86 S SMI1-KNR4 cell-wall
NMFLEBOF_02212 6.1e-308 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMFLEBOF_02213 3.7e-102 yokH G SMI1 / KNR4 family
NMFLEBOF_02214 7.8e-274 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
NMFLEBOF_02215 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
NMFLEBOF_02216 1.7e-134 yobQ K helix_turn_helix, arabinose operon control protein
NMFLEBOF_02217 5e-139 yobR 2.3.1.1 J FR47-like protein
NMFLEBOF_02218 9.6e-98 yobS K Transcriptional regulator
NMFLEBOF_02219 6.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
NMFLEBOF_02220 3.1e-86 yobU K Bacterial transcription activator, effector binding domain
NMFLEBOF_02221 7.4e-172 yobV K WYL domain
NMFLEBOF_02222 3e-93 yobW
NMFLEBOF_02223 1e-51 czrA K transcriptional
NMFLEBOF_02224 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
NMFLEBOF_02226 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02227 1.5e-92 yozB S membrane
NMFLEBOF_02228 9.2e-144
NMFLEBOF_02229 7.5e-91 yocC
NMFLEBOF_02230 7.6e-188 yocD 3.4.17.13 V peptidase S66
NMFLEBOF_02231 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
NMFLEBOF_02232 4.6e-197 desK 2.7.13.3 T Histidine kinase
NMFLEBOF_02233 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_02234 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
NMFLEBOF_02235 0.0 recQ 3.6.4.12 L DNA helicase
NMFLEBOF_02236 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMFLEBOF_02237 7.4e-83 dksA T general stress protein
NMFLEBOF_02238 4.7e-42 yocL
NMFLEBOF_02239 2e-30
NMFLEBOF_02240 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
NMFLEBOF_02241 1.1e-40 yozN
NMFLEBOF_02242 1.9e-36 yocN
NMFLEBOF_02243 4.2e-56 yozO S Bacterial PH domain
NMFLEBOF_02244 2.7e-31 yozC
NMFLEBOF_02245 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
NMFLEBOF_02246 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
NMFLEBOF_02247 8e-162 sodA 1.15.1.1 P Superoxide dismutase
NMFLEBOF_02248 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
NMFLEBOF_02249 5.6e-167 yocS S -transporter
NMFLEBOF_02250 2.2e-192 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
NMFLEBOF_02251 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
NMFLEBOF_02252 0.0 yojO P Von Willebrand factor
NMFLEBOF_02253 1e-159 yojN S ATPase family associated with various cellular activities (AAA)
NMFLEBOF_02254 5.6e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NMFLEBOF_02255 2.8e-195 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
NMFLEBOF_02256 1.3e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
NMFLEBOF_02257 5.8e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NMFLEBOF_02259 1e-243 norM V Multidrug efflux pump
NMFLEBOF_02260 7.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMFLEBOF_02261 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02263 2.1e-125 yojG S deacetylase
NMFLEBOF_02264 2.2e-60 yojF S Protein of unknown function (DUF1806)
NMFLEBOF_02265 1.5e-43
NMFLEBOF_02266 2.5e-161 rarD S -transporter
NMFLEBOF_02267 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
NMFLEBOF_02268 1.5e-09
NMFLEBOF_02269 5.5e-205 gntP EG COG2610 H gluconate symporter and related permeases
NMFLEBOF_02270 8e-64 yodA S tautomerase
NMFLEBOF_02271 4.4e-55 yodB K transcriptional
NMFLEBOF_02272 4.8e-108 yodC C nitroreductase
NMFLEBOF_02273 2.5e-112 mhqD S Carboxylesterase
NMFLEBOF_02274 1.1e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
NMFLEBOF_02275 8.1e-28 S Protein of unknown function (DUF3311)
NMFLEBOF_02276 1.9e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMFLEBOF_02277 5.9e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
NMFLEBOF_02278 5.4e-127 yodH Q Methyltransferase
NMFLEBOF_02279 4.4e-23 yodI
NMFLEBOF_02280 2.1e-138 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
NMFLEBOF_02281 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
NMFLEBOF_02282 5.3e-09
NMFLEBOF_02283 3.6e-54 yodL S YodL-like
NMFLEBOF_02284 4.3e-104 yodM 3.6.1.27 I Acid phosphatase homologues
NMFLEBOF_02285 2.8e-24 yozD S YozD-like protein
NMFLEBOF_02287 6e-123 yodN
NMFLEBOF_02288 3.1e-36 yozE S Belongs to the UPF0346 family
NMFLEBOF_02289 2.9e-47 yokU S YokU-like protein, putative antitoxin
NMFLEBOF_02290 4.8e-276 kamA 5.4.3.2 E lysine 2,3-aminomutase
NMFLEBOF_02291 3.3e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
NMFLEBOF_02292 1.3e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
NMFLEBOF_02293 9e-60 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMFLEBOF_02294 8e-45 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMFLEBOF_02295 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMFLEBOF_02296 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
NMFLEBOF_02298 4.1e-144 yiiD K acetyltransferase
NMFLEBOF_02299 2.2e-256 cgeD M maturation of the outermost layer of the spore
NMFLEBOF_02300 5.9e-38 cgeC
NMFLEBOF_02301 5.3e-63 cgeA
NMFLEBOF_02302 2.2e-176 cgeB S Spore maturation protein
NMFLEBOF_02303 1.9e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
NMFLEBOF_02304 8.1e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
NMFLEBOF_02305 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NMFLEBOF_02306 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NMFLEBOF_02307 1.6e-70 ypoP K transcriptional
NMFLEBOF_02308 4.9e-222 mepA V MATE efflux family protein
NMFLEBOF_02309 1.2e-28 ypmT S Uncharacterized ympT
NMFLEBOF_02310 9.4e-98 ypmS S protein conserved in bacteria
NMFLEBOF_02311 1.6e-137 ypmR E GDSL-like Lipase/Acylhydrolase
NMFLEBOF_02312 2.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
NMFLEBOF_02313 3.1e-40 ypmP S Protein of unknown function (DUF2535)
NMFLEBOF_02314 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NMFLEBOF_02315 1.5e-183 pspF K Transcriptional regulator
NMFLEBOF_02316 2.7e-109 hlyIII S protein, Hemolysin III
NMFLEBOF_02317 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
NMFLEBOF_02318 8.2e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NMFLEBOF_02319 2.3e-48 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMFLEBOF_02320 2.6e-34 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMFLEBOF_02321 5e-113 ypjP S YpjP-like protein
NMFLEBOF_02322 6.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
NMFLEBOF_02323 1.7e-75 yphP S Belongs to the UPF0403 family
NMFLEBOF_02324 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
NMFLEBOF_02325 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
NMFLEBOF_02326 2.4e-110 ypgQ S phosphohydrolase
NMFLEBOF_02327 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
NMFLEBOF_02328 8.9e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
NMFLEBOF_02329 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
NMFLEBOF_02330 7.9e-31 cspD K Cold-shock protein
NMFLEBOF_02331 3.8e-16 degR
NMFLEBOF_02332 8.1e-31 S Protein of unknown function (DUF2564)
NMFLEBOF_02333 3e-29 ypeQ S Zinc-finger
NMFLEBOF_02334 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
NMFLEBOF_02335 6.6e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NMFLEBOF_02336 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
NMFLEBOF_02338 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
NMFLEBOF_02339 2e-07
NMFLEBOF_02340 2.9e-38 ypbS S Protein of unknown function (DUF2533)
NMFLEBOF_02341 0.0 ypbR S Dynamin family
NMFLEBOF_02342 1.1e-86 ypbQ S protein conserved in bacteria
NMFLEBOF_02343 6e-33 bcsA Q Naringenin-chalcone synthase
NMFLEBOF_02344 9.6e-158 bcsA Q Naringenin-chalcone synthase
NMFLEBOF_02345 3.8e-227 pbuX F xanthine
NMFLEBOF_02346 1.4e-96 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NMFLEBOF_02347 1.5e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NMFLEBOF_02348 5.6e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
NMFLEBOF_02349 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
NMFLEBOF_02350 2.4e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
NMFLEBOF_02351 4.4e-186 ptxS K transcriptional
NMFLEBOF_02352 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
NMFLEBOF_02353 4.8e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_02354 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
NMFLEBOF_02356 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NMFLEBOF_02357 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NMFLEBOF_02358 1.8e-90 ypsA S Belongs to the UPF0398 family
NMFLEBOF_02359 1.6e-235 yprB L RNase_H superfamily
NMFLEBOF_02360 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
NMFLEBOF_02361 1.1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
NMFLEBOF_02362 8e-70 hspX O Belongs to the small heat shock protein (HSP20) family
NMFLEBOF_02363 5.1e-47 yppG S YppG-like protein
NMFLEBOF_02365 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
NMFLEBOF_02368 5.4e-186 yppC S Protein of unknown function (DUF2515)
NMFLEBOF_02369 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NMFLEBOF_02370 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
NMFLEBOF_02371 4.7e-93 ypoC
NMFLEBOF_02372 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NMFLEBOF_02373 2.8e-128 dnaD L DNA replication protein DnaD
NMFLEBOF_02374 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
NMFLEBOF_02375 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
NMFLEBOF_02376 2.2e-79 ypmB S protein conserved in bacteria
NMFLEBOF_02377 6.7e-23 ypmA S Protein of unknown function (DUF4264)
NMFLEBOF_02378 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NMFLEBOF_02379 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
NMFLEBOF_02380 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NMFLEBOF_02381 2.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
NMFLEBOF_02382 1.9e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NMFLEBOF_02383 4.6e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NMFLEBOF_02384 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
NMFLEBOF_02385 1.7e-128 bshB1 S proteins, LmbE homologs
NMFLEBOF_02386 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
NMFLEBOF_02387 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NMFLEBOF_02388 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
NMFLEBOF_02389 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
NMFLEBOF_02390 1.1e-141 ypjB S sporulation protein
NMFLEBOF_02391 1.5e-98 ypjA S membrane
NMFLEBOF_02392 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
NMFLEBOF_02393 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
NMFLEBOF_02394 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
NMFLEBOF_02395 4.2e-77 ypiF S Protein of unknown function (DUF2487)
NMFLEBOF_02396 2.8e-99 ypiB S Belongs to the UPF0302 family
NMFLEBOF_02397 5.9e-233 S COG0457 FOG TPR repeat
NMFLEBOF_02398 2.9e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
NMFLEBOF_02399 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
NMFLEBOF_02400 1.4e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NMFLEBOF_02401 4.7e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
NMFLEBOF_02402 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NMFLEBOF_02403 5.1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
NMFLEBOF_02404 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
NMFLEBOF_02405 6.7e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NMFLEBOF_02406 1.8e-292 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NMFLEBOF_02407 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
NMFLEBOF_02408 2.9e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NMFLEBOF_02409 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NMFLEBOF_02410 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
NMFLEBOF_02411 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
NMFLEBOF_02412 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMFLEBOF_02413 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NMFLEBOF_02414 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
NMFLEBOF_02415 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
NMFLEBOF_02416 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
NMFLEBOF_02418 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02419 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NMFLEBOF_02420 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NMFLEBOF_02421 2.3e-136 yphF
NMFLEBOF_02422 2e-18 yphE S Protein of unknown function (DUF2768)
NMFLEBOF_02423 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NMFLEBOF_02424 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NMFLEBOF_02425 7.9e-28 ypzH
NMFLEBOF_02426 2.5e-161 seaA S YIEGIA protein
NMFLEBOF_02427 6.7e-102 yphA
NMFLEBOF_02428 1e-07 S YpzI-like protein
NMFLEBOF_02429 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_02430 1.4e-45 L transposase activity
NMFLEBOF_02431 2.7e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NMFLEBOF_02432 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
NMFLEBOF_02433 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NMFLEBOF_02434 1.8e-23 S Family of unknown function (DUF5359)
NMFLEBOF_02435 2.3e-108 ypfA M Flagellar protein YcgR
NMFLEBOF_02436 1.4e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
NMFLEBOF_02437 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
NMFLEBOF_02438 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
NMFLEBOF_02439 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
NMFLEBOF_02440 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMFLEBOF_02441 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
NMFLEBOF_02442 2.3e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
NMFLEBOF_02443 8.2e-81 ypbF S Protein of unknown function (DUF2663)
NMFLEBOF_02444 4.6e-81 ypbE M Lysin motif
NMFLEBOF_02445 1.1e-99 ypbD S metal-dependent membrane protease
NMFLEBOF_02446 8.6e-284 recQ 3.6.4.12 L DNA helicase
NMFLEBOF_02447 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
NMFLEBOF_02448 4.7e-41 fer C Ferredoxin
NMFLEBOF_02449 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NMFLEBOF_02450 3.3e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFLEBOF_02451 5.5e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
NMFLEBOF_02452 5.9e-107 rsiX
NMFLEBOF_02453 1.4e-16 rsiX
NMFLEBOF_02454 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_02455 0.0 resE 2.7.13.3 T Histidine kinase
NMFLEBOF_02456 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_02457 2.6e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
NMFLEBOF_02458 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
NMFLEBOF_02459 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
NMFLEBOF_02460 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMFLEBOF_02461 1.9e-87 spmB S Spore maturation protein
NMFLEBOF_02462 3.5e-103 spmA S Spore maturation protein
NMFLEBOF_02463 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
NMFLEBOF_02464 7.6e-97 ypuI S Protein of unknown function (DUF3907)
NMFLEBOF_02465 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NMFLEBOF_02466 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NMFLEBOF_02467 3e-90 ypuF S Domain of unknown function (DUF309)
NMFLEBOF_02468 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_02469 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NMFLEBOF_02470 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NMFLEBOF_02471 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
NMFLEBOF_02472 5.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NMFLEBOF_02473 7.8e-55 ypuD
NMFLEBOF_02474 8.9e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
NMFLEBOF_02476 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
NMFLEBOF_02478 3.6e-49 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMFLEBOF_02479 3.6e-31 S Pfam Transposase IS66
NMFLEBOF_02480 2.5e-26
NMFLEBOF_02481 6.8e-53 3.4.24.28 F DNA/RNA non-specific endonuclease
NMFLEBOF_02483 5.6e-65 O Papain family cysteine protease
NMFLEBOF_02484 5e-11
NMFLEBOF_02485 2.7e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_02486 1.8e-87 S Protein of unknown function (DUF3800)
NMFLEBOF_02490 4e-108 S aspartate phosphatase
NMFLEBOF_02491 9.5e-80 S SMI1-KNR4 cell-wall
NMFLEBOF_02492 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_02493 1.2e-27 S Protein of unknown function (DUF1433)
NMFLEBOF_02494 4e-238 I Pfam Lipase (class 3)
NMFLEBOF_02495 6.7e-16
NMFLEBOF_02497 1.3e-18 K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_02502 4.2e-74 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMFLEBOF_02503 2.6e-31 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NMFLEBOF_02504 3.6e-149 ypuA S Secreted protein
NMFLEBOF_02505 2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NMFLEBOF_02506 1.7e-271 spoVAF EG Stage V sporulation protein AF
NMFLEBOF_02507 1.4e-110 spoVAEA S stage V sporulation protein
NMFLEBOF_02508 2.2e-57 spoVAEB S stage V sporulation protein
NMFLEBOF_02509 1.5e-191 spoVAD I Stage V sporulation protein AD
NMFLEBOF_02510 2.3e-78 spoVAC S stage V sporulation protein AC
NMFLEBOF_02511 1e-67 spoVAB S Stage V sporulation protein AB
NMFLEBOF_02512 2.8e-111 spoVAA S Stage V sporulation protein AA
NMFLEBOF_02513 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_02514 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
NMFLEBOF_02515 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
NMFLEBOF_02516 6.3e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
NMFLEBOF_02517 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
NMFLEBOF_02518 1.3e-229 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
NMFLEBOF_02519 9.7e-166 xerD L recombinase XerD
NMFLEBOF_02520 3.7e-37 S Protein of unknown function (DUF4227)
NMFLEBOF_02521 2.4e-80 fur P Belongs to the Fur family
NMFLEBOF_02522 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
NMFLEBOF_02523 3.2e-30 yqkK
NMFLEBOF_02524 5.5e-242 mleA 1.1.1.38 C malic enzyme
NMFLEBOF_02525 9.1e-235 mleN C Na H antiporter
NMFLEBOF_02526 1.4e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
NMFLEBOF_02527 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
NMFLEBOF_02528 4.5e-58 ansR K Transcriptional regulator
NMFLEBOF_02529 3.6e-221 yqxK 3.6.4.12 L DNA helicase
NMFLEBOF_02530 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
NMFLEBOF_02532 2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
NMFLEBOF_02533 7e-12 yqkE S Protein of unknown function (DUF3886)
NMFLEBOF_02534 1.6e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
NMFLEBOF_02535 9.4e-39 yqkC S Protein of unknown function (DUF2552)
NMFLEBOF_02536 2.8e-54 yqkB S Belongs to the HesB IscA family
NMFLEBOF_02537 9.8e-194 yqkA K GrpB protein
NMFLEBOF_02538 7.5e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
NMFLEBOF_02539 3.6e-87 yqjY K acetyltransferase
NMFLEBOF_02540 1.7e-49 S YolD-like protein
NMFLEBOF_02541 3.2e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMFLEBOF_02543 1.3e-224 yqjV G Major Facilitator Superfamily
NMFLEBOF_02545 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_02546 7e-178 coaA 2.7.1.33 F Pantothenic acid kinase
NMFLEBOF_02547 4.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
NMFLEBOF_02548 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_02549 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMFLEBOF_02550 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFLEBOF_02551 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02553 0.0 rocB E arginine degradation protein
NMFLEBOF_02554 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
NMFLEBOF_02555 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
NMFLEBOF_02556 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMFLEBOF_02557 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NMFLEBOF_02558 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NMFLEBOF_02559 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMFLEBOF_02560 9.9e-233 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NMFLEBOF_02561 6.2e-24 yqzJ
NMFLEBOF_02562 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMFLEBOF_02563 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
NMFLEBOF_02564 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
NMFLEBOF_02565 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
NMFLEBOF_02566 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
NMFLEBOF_02567 3e-98 yqjB S protein conserved in bacteria
NMFLEBOF_02568 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
NMFLEBOF_02569 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMFLEBOF_02570 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
NMFLEBOF_02571 6.9e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
NMFLEBOF_02572 9.3e-77 yqiW S Belongs to the UPF0403 family
NMFLEBOF_02573 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
NMFLEBOF_02574 3.9e-207 norA EGP Major facilitator Superfamily
NMFLEBOF_02575 1.1e-150 bmrR K helix_turn_helix, mercury resistance
NMFLEBOF_02576 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
NMFLEBOF_02577 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
NMFLEBOF_02578 4.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
NMFLEBOF_02579 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
NMFLEBOF_02580 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
NMFLEBOF_02581 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMFLEBOF_02582 5.6e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
NMFLEBOF_02583 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
NMFLEBOF_02584 4e-34 yqzF S Protein of unknown function (DUF2627)
NMFLEBOF_02585 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NMFLEBOF_02586 9.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
NMFLEBOF_02587 1.5e-208 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
NMFLEBOF_02588 1.3e-210 mmgC I acyl-CoA dehydrogenase
NMFLEBOF_02589 1.2e-155 hbdA 1.1.1.157 I Dehydrogenase
NMFLEBOF_02590 7.2e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
NMFLEBOF_02591 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NMFLEBOF_02592 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
NMFLEBOF_02593 6e-27
NMFLEBOF_02594 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
NMFLEBOF_02596 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
NMFLEBOF_02597 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
NMFLEBOF_02598 1.4e-306 recN L May be involved in recombinational repair of damaged DNA
NMFLEBOF_02599 1.7e-78 argR K Regulates arginine biosynthesis genes
NMFLEBOF_02600 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
NMFLEBOF_02601 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NMFLEBOF_02602 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NMFLEBOF_02603 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMFLEBOF_02604 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NMFLEBOF_02605 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NMFLEBOF_02606 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NMFLEBOF_02607 6.2e-67 yqhY S protein conserved in bacteria
NMFLEBOF_02608 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
NMFLEBOF_02609 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NMFLEBOF_02610 9.9e-91 spoIIIAH S SpoIIIAH-like protein
NMFLEBOF_02611 3.4e-102 spoIIIAG S stage III sporulation protein AG
NMFLEBOF_02612 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
NMFLEBOF_02613 4.9e-197 spoIIIAE S stage III sporulation protein AE
NMFLEBOF_02614 2.3e-58 spoIIIAD S Stage III sporulation protein AD
NMFLEBOF_02615 7.6e-29 spoIIIAC S stage III sporulation protein AC
NMFLEBOF_02616 4.1e-84 spoIIIAB S Stage III sporulation protein
NMFLEBOF_02617 1.2e-171 spoIIIAA S stage III sporulation protein AA
NMFLEBOF_02618 7.9e-37 yqhV S Protein of unknown function (DUF2619)
NMFLEBOF_02619 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NMFLEBOF_02620 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
NMFLEBOF_02621 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
NMFLEBOF_02622 2.3e-93 yqhR S Conserved membrane protein YqhR
NMFLEBOF_02623 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
NMFLEBOF_02624 2.2e-61 yqhP
NMFLEBOF_02625 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
NMFLEBOF_02626 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
NMFLEBOF_02627 5.7e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
NMFLEBOF_02628 3.3e-62 yqhL P COG0607 Rhodanese-related sulfurtransferase
NMFLEBOF_02629 1.8e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMFLEBOF_02630 2.7e-252 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NMFLEBOF_02631 5.3e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
NMFLEBOF_02632 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMFLEBOF_02633 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
NMFLEBOF_02634 1.2e-24 sinI S Anti-repressor SinI
NMFLEBOF_02635 1e-54 sinR K transcriptional
NMFLEBOF_02636 5.6e-141 tasA S Cell division protein FtsN
NMFLEBOF_02637 2.5e-58 sipW 3.4.21.89 U Signal peptidase
NMFLEBOF_02638 1.1e-112 yqxM
NMFLEBOF_02639 7.3e-54 yqzG S Protein of unknown function (DUF3889)
NMFLEBOF_02640 5.2e-26 yqzE S YqzE-like protein
NMFLEBOF_02641 8.8e-44 S ComG operon protein 7
NMFLEBOF_02642 2.7e-45 comGF U Putative Competence protein ComGF
NMFLEBOF_02643 1.3e-57 comGE
NMFLEBOF_02644 2.4e-70 gspH NU protein transport across the cell outer membrane
NMFLEBOF_02645 1.4e-47 comGC U Required for transformation and DNA binding
NMFLEBOF_02646 2.5e-173 comGB NU COG1459 Type II secretory pathway, component PulF
NMFLEBOF_02647 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NMFLEBOF_02649 2.1e-174 corA P Mg2 transporter protein
NMFLEBOF_02650 4.4e-239 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMFLEBOF_02651 1.3e-148 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
NMFLEBOF_02653 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
NMFLEBOF_02654 1.8e-37 yqgY S Protein of unknown function (DUF2626)
NMFLEBOF_02656 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02657 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
NMFLEBOF_02658 8.9e-23 yqgW S Protein of unknown function (DUF2759)
NMFLEBOF_02659 6.9e-50 yqgV S Thiamine-binding protein
NMFLEBOF_02660 5.1e-198 yqgU
NMFLEBOF_02661 2.1e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
NMFLEBOF_02662 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMFLEBOF_02663 5.8e-180 glcK 2.7.1.2 G Glucokinase
NMFLEBOF_02664 3.1e-33 yqgQ S Protein conserved in bacteria
NMFLEBOF_02665 1.2e-259 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
NMFLEBOF_02666 2.5e-09 yqgO
NMFLEBOF_02667 5.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NMFLEBOF_02668 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NMFLEBOF_02669 1.2e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
NMFLEBOF_02671 3.5e-50 yqzD
NMFLEBOF_02672 7.3e-72 yqzC S YceG-like family
NMFLEBOF_02673 3.6e-38 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMFLEBOF_02674 1e-85 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMFLEBOF_02675 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NMFLEBOF_02676 4.4e-158 pstA P Phosphate transport system permease
NMFLEBOF_02677 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NMFLEBOF_02678 2.6e-150 pstS P Phosphate
NMFLEBOF_02679 0.0 pbpA 3.4.16.4 M penicillin-binding protein
NMFLEBOF_02680 2.5e-231 yqgE EGP Major facilitator superfamily
NMFLEBOF_02681 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
NMFLEBOF_02682 2.6e-72 yqgC S protein conserved in bacteria
NMFLEBOF_02683 8.7e-131 yqgB S Protein of unknown function (DUF1189)
NMFLEBOF_02684 5.8e-46 yqfZ M LysM domain
NMFLEBOF_02685 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NMFLEBOF_02686 2.8e-61 yqfX S membrane
NMFLEBOF_02687 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
NMFLEBOF_02688 1.9e-77 zur P Belongs to the Fur family
NMFLEBOF_02689 8.2e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
NMFLEBOF_02690 2.1e-36 yqfT S Protein of unknown function (DUF2624)
NMFLEBOF_02691 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NMFLEBOF_02692 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NMFLEBOF_02694 2.9e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NMFLEBOF_02695 1.8e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NMFLEBOF_02696 3e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
NMFLEBOF_02697 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
NMFLEBOF_02698 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NMFLEBOF_02699 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NMFLEBOF_02700 4.5e-88 yaiI S Belongs to the UPF0178 family
NMFLEBOF_02701 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NMFLEBOF_02702 4.5e-112 ccpN K CBS domain
NMFLEBOF_02703 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NMFLEBOF_02704 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NMFLEBOF_02705 1.4e-144 recO L Involved in DNA repair and RecF pathway recombination
NMFLEBOF_02706 8.4e-19 S YqzL-like protein
NMFLEBOF_02707 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NMFLEBOF_02708 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
NMFLEBOF_02709 7.9e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
NMFLEBOF_02710 8.8e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NMFLEBOF_02711 0.0 yqfF S membrane-associated HD superfamily hydrolase
NMFLEBOF_02713 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
NMFLEBOF_02714 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
NMFLEBOF_02715 2.7e-45 yqfC S sporulation protein YqfC
NMFLEBOF_02716 1.3e-19 yqfB
NMFLEBOF_02717 4.3e-122 yqfA S UPF0365 protein
NMFLEBOF_02718 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
NMFLEBOF_02719 8.3e-65 yqeY S Yqey-like protein
NMFLEBOF_02720 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NMFLEBOF_02721 1.9e-156 yqeW P COG1283 Na phosphate symporter
NMFLEBOF_02722 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
NMFLEBOF_02723 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
NMFLEBOF_02724 1.6e-174 prmA J Methylates ribosomal protein L11
NMFLEBOF_02725 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NMFLEBOF_02726 0.0 dnaK O Heat shock 70 kDa protein
NMFLEBOF_02727 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NMFLEBOF_02728 8.9e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NMFLEBOF_02729 1.2e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
NMFLEBOF_02730 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NMFLEBOF_02731 7.2e-53 yqxA S Protein of unknown function (DUF3679)
NMFLEBOF_02732 1.5e-222 spoIIP M stage II sporulation protein P
NMFLEBOF_02733 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NMFLEBOF_02734 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
NMFLEBOF_02735 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
NMFLEBOF_02736 4.1e-15 S YqzM-like protein
NMFLEBOF_02737 0.0 comEC S Competence protein ComEC
NMFLEBOF_02738 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
NMFLEBOF_02739 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
NMFLEBOF_02740 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NMFLEBOF_02741 4.6e-137 yqeM Q Methyltransferase
NMFLEBOF_02742 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NMFLEBOF_02743 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
NMFLEBOF_02744 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NMFLEBOF_02745 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
NMFLEBOF_02746 6.6e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NMFLEBOF_02747 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
NMFLEBOF_02748 5.3e-95 yqeG S hydrolase of the HAD superfamily
NMFLEBOF_02750 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
NMFLEBOF_02751 5.4e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_02752 8.8e-105 yqeD S SNARE associated Golgi protein
NMFLEBOF_02753 2.1e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
NMFLEBOF_02754 2.8e-131 yqeB
NMFLEBOF_02755 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
NMFLEBOF_02756 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NMFLEBOF_02757 1.1e-256 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMFLEBOF_02758 5e-154 K Transcriptional regulator
NMFLEBOF_02759 3.9e-66 K Glyoxalase bleomycin resistance protein dioxygenase
NMFLEBOF_02761 2.6e-208 S Aspartate phosphatase response regulator
NMFLEBOF_02762 3e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMFLEBOF_02763 1.5e-178 L nucleic acid phosphodiester bond hydrolysis
NMFLEBOF_02764 4.8e-32 L nucleic acid phosphodiester bond hydrolysis
NMFLEBOF_02766 1.9e-29 S SMI1 / KNR4 family
NMFLEBOF_02767 4e-22 S SMI1-KNR4 cell-wall
NMFLEBOF_02768 5.3e-46
NMFLEBOF_02772 6.6e-28 S Suppressor of fused protein (SUFU)
NMFLEBOF_02773 2.5e-30
NMFLEBOF_02774 1.1e-220 L Transposase
NMFLEBOF_02775 9.9e-119 L PhoH-like protein
NMFLEBOF_02777 1.5e-21 xkdM S Phage tail tube protein
NMFLEBOF_02778 2.1e-10
NMFLEBOF_02784 3.1e-150 bltR K helix_turn_helix, mercury resistance
NMFLEBOF_02785 3.7e-191 blt EGP Major facilitator Superfamily
NMFLEBOF_02786 5.9e-82 bltD 2.3.1.57 K FR47-like protein
NMFLEBOF_02787 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_02788 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
NMFLEBOF_02789 3.9e-16 S YrzO-like protein
NMFLEBOF_02790 7.3e-167 yrdR EG EamA-like transporter family
NMFLEBOF_02791 3.9e-159 yrdQ K Transcriptional regulator
NMFLEBOF_02792 1.1e-197 trkA P Oxidoreductase
NMFLEBOF_02793 1.5e-153 czcD P COG1230 Co Zn Cd efflux system component
NMFLEBOF_02794 1.9e-198 L COG3385 FOG Transposase and inactivated derivatives
NMFLEBOF_02795 3e-17 yodA S tautomerase
NMFLEBOF_02796 2.3e-224 brnQ E Component of the transport system for branched-chain amino acids
NMFLEBOF_02797 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
NMFLEBOF_02798 3.7e-137 azlC E AzlC protein
NMFLEBOF_02799 5.3e-78 bkdR K helix_turn_helix ASNC type
NMFLEBOF_02800 1.1e-40 yrdF K ribonuclease inhibitor
NMFLEBOF_02801 2e-100 yrdC 3.5.1.19 Q Isochorismatase family
NMFLEBOF_02802 3.3e-57 S Protein of unknown function (DUF2568)
NMFLEBOF_02803 1.4e-89 yrdA S DinB family
NMFLEBOF_02804 8.7e-164 aadK G Streptomycin adenylyltransferase
NMFLEBOF_02805 1.2e-191 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
NMFLEBOF_02806 9.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMFLEBOF_02807 8.7e-125 yrpD S Domain of unknown function, YrpD
NMFLEBOF_02809 7.6e-111 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
NMFLEBOF_02810 1e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_02811 1.7e-187 yrpG C Aldo/keto reductase family
NMFLEBOF_02812 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
NMFLEBOF_02813 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_02814 7.6e-149 S Alpha beta hydrolase
NMFLEBOF_02815 2.6e-61 T sh3 domain protein
NMFLEBOF_02816 2.4e-61 T sh3 domain protein
NMFLEBOF_02817 1.3e-66 E Glyoxalase-like domain
NMFLEBOF_02818 5.3e-37 yraG
NMFLEBOF_02819 6.4e-63 yraF M Spore coat protein
NMFLEBOF_02820 1.1e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMFLEBOF_02821 7.5e-26 yraE
NMFLEBOF_02822 1.1e-49 yraD M Spore coat protein
NMFLEBOF_02823 1.3e-46 yraB K helix_turn_helix, mercury resistance
NMFLEBOF_02824 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
NMFLEBOF_02825 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
NMFLEBOF_02826 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
NMFLEBOF_02827 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMFLEBOF_02828 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
NMFLEBOF_02829 1.1e-115 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
NMFLEBOF_02830 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
NMFLEBOF_02831 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
NMFLEBOF_02832 0.0 levR K PTS system fructose IIA component
NMFLEBOF_02833 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_02834 3.6e-106 yrhP E LysE type translocator
NMFLEBOF_02835 5.3e-150 yrhO K Archaeal transcriptional regulator TrmB
NMFLEBOF_02836 6.2e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_02837 5.5e-150 rsiV S Protein of unknown function (DUF3298)
NMFLEBOF_02838 4.8e-69 yrhL I Acyltransferase family
NMFLEBOF_02839 3.3e-224 yrhL I Acyltransferase family
NMFLEBOF_02840 2.6e-43 yrhK S YrhK-like protein
NMFLEBOF_02841 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
NMFLEBOF_02842 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
NMFLEBOF_02843 4.2e-95 yrhH Q methyltransferase
NMFLEBOF_02846 1.2e-141 focA P Formate nitrite
NMFLEBOF_02847 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
NMFLEBOF_02848 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
NMFLEBOF_02849 7.1e-78 yrhD S Protein of unknown function (DUF1641)
NMFLEBOF_02850 1.8e-34 yrhC S YrhC-like protein
NMFLEBOF_02851 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
NMFLEBOF_02852 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
NMFLEBOF_02853 3.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NMFLEBOF_02854 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
NMFLEBOF_02855 1e-25 yrzA S Protein of unknown function (DUF2536)
NMFLEBOF_02856 5.5e-63 yrrS S Protein of unknown function (DUF1510)
NMFLEBOF_02857 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
NMFLEBOF_02858 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NMFLEBOF_02859 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
NMFLEBOF_02860 2.7e-246 yegQ O COG0826 Collagenase and related proteases
NMFLEBOF_02861 4.3e-172 yegQ O Peptidase U32
NMFLEBOF_02862 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
NMFLEBOF_02864 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02865 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NMFLEBOF_02866 1.2e-45 yrzB S Belongs to the UPF0473 family
NMFLEBOF_02867 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NMFLEBOF_02868 1.7e-41 yrzL S Belongs to the UPF0297 family
NMFLEBOF_02869 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NMFLEBOF_02870 7.8e-170 yrrI S AI-2E family transporter
NMFLEBOF_02871 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
NMFLEBOF_02872 7.7e-141 glnH ET Belongs to the bacterial solute-binding protein 3 family
NMFLEBOF_02873 2.6e-107 gluC P ABC transporter
NMFLEBOF_02874 7.6e-107 glnP P ABC transporter
NMFLEBOF_02875 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_02878 9.8e-31 yrzR
NMFLEBOF_02879 6.6e-81 yrrD S protein conserved in bacteria
NMFLEBOF_02880 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NMFLEBOF_02881 1.4e-15 S COG0457 FOG TPR repeat
NMFLEBOF_02882 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NMFLEBOF_02883 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
NMFLEBOF_02884 1.2e-70 cymR K Transcriptional regulator
NMFLEBOF_02885 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
NMFLEBOF_02886 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
NMFLEBOF_02887 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NMFLEBOF_02888 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NMFLEBOF_02890 5.7e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
NMFLEBOF_02891 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NMFLEBOF_02892 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NMFLEBOF_02893 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NMFLEBOF_02894 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NMFLEBOF_02895 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
NMFLEBOF_02896 8.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
NMFLEBOF_02897 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NMFLEBOF_02898 9.4e-49 yrzD S Post-transcriptional regulator
NMFLEBOF_02899 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_02900 1.6e-112 yrbG S membrane
NMFLEBOF_02901 1.5e-74 yrzE S Protein of unknown function (DUF3792)
NMFLEBOF_02902 8e-39 yajC U Preprotein translocase subunit YajC
NMFLEBOF_02903 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
NMFLEBOF_02904 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NMFLEBOF_02905 2.6e-18 yrzS S Protein of unknown function (DUF2905)
NMFLEBOF_02906 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NMFLEBOF_02907 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NMFLEBOF_02908 4.8e-93 bofC S BofC C-terminal domain
NMFLEBOF_02909 5.3e-253 csbX EGP Major facilitator Superfamily
NMFLEBOF_02910 6.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
NMFLEBOF_02911 1.9e-118 yrzF T serine threonine protein kinase
NMFLEBOF_02913 5.2e-51 S Family of unknown function (DUF5412)
NMFLEBOF_02914 3.1e-262 alsT E Sodium alanine symporter
NMFLEBOF_02915 5.5e-127 yebC K transcriptional regulatory protein
NMFLEBOF_02916 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMFLEBOF_02917 3.1e-156 safA M spore coat assembly protein SafA
NMFLEBOF_02918 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NMFLEBOF_02919 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
NMFLEBOF_02920 2e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
NMFLEBOF_02921 9.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
NMFLEBOF_02922 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
NMFLEBOF_02923 3.3e-163 pheA 4.2.1.51 E Prephenate dehydratase
NMFLEBOF_02924 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
NMFLEBOF_02925 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NMFLEBOF_02926 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
NMFLEBOF_02927 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NMFLEBOF_02928 4.1e-56 ysxB J ribosomal protein
NMFLEBOF_02929 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NMFLEBOF_02930 2e-160 spoIVFB S Stage IV sporulation protein
NMFLEBOF_02931 1.4e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
NMFLEBOF_02932 3.3e-144 minD D Belongs to the ParA family
NMFLEBOF_02933 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
NMFLEBOF_02934 1.4e-84 mreD M shape-determining protein
NMFLEBOF_02935 1.1e-156 mreC M Involved in formation and maintenance of cell shape
NMFLEBOF_02936 1.8e-184 mreB D Rod shape-determining protein MreB
NMFLEBOF_02937 1.3e-125 radC E Belongs to the UPF0758 family
NMFLEBOF_02938 2.4e-101 maf D septum formation protein Maf
NMFLEBOF_02939 6e-164 spoIIB S Sporulation related domain
NMFLEBOF_02940 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
NMFLEBOF_02941 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NMFLEBOF_02942 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NMFLEBOF_02943 1.6e-25
NMFLEBOF_02944 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NMFLEBOF_02945 3.3e-186 spoVID M stage VI sporulation protein D
NMFLEBOF_02946 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
NMFLEBOF_02947 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
NMFLEBOF_02948 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
NMFLEBOF_02949 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
NMFLEBOF_02950 3.6e-146 hemX O cytochrome C
NMFLEBOF_02951 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NMFLEBOF_02952 5.4e-89 ysxD
NMFLEBOF_02953 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
NMFLEBOF_02954 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NMFLEBOF_02955 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
NMFLEBOF_02956 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NMFLEBOF_02957 3.5e-225 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NMFLEBOF_02958 7.3e-186 ysoA H Tetratricopeptide repeat
NMFLEBOF_02959 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMFLEBOF_02960 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NMFLEBOF_02961 1.1e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
NMFLEBOF_02962 7.1e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NMFLEBOF_02963 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NMFLEBOF_02964 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
NMFLEBOF_02965 0.0 ilvB 2.2.1.6 E Acetolactate synthase
NMFLEBOF_02967 1.3e-34 ysnE K acetyltransferase
NMFLEBOF_02968 5.5e-131 ysnF S protein conserved in bacteria
NMFLEBOF_02969 1.4e-45 L transposase activity
NMFLEBOF_02970 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_02971 1.9e-66 pinR3 L Resolvase, N terminal domain
NMFLEBOF_02972 2.3e-78 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
NMFLEBOF_02973 1e-249 hsdM 2.1.1.72 L type I restriction-modification system
NMFLEBOF_02974 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
NMFLEBOF_02975 6.3e-43
NMFLEBOF_02977 1.6e-132 L Phage integrase family
NMFLEBOF_02979 1.4e-92 ysnB S Phosphoesterase
NMFLEBOF_02980 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NMFLEBOF_02981 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NMFLEBOF_02982 2.9e-196 gerM S COG5401 Spore germination protein
NMFLEBOF_02983 1.2e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NMFLEBOF_02984 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
NMFLEBOF_02985 3.3e-30 gerE K Transcriptional regulator
NMFLEBOF_02986 9.4e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
NMFLEBOF_02987 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMFLEBOF_02988 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
NMFLEBOF_02989 2.4e-107 sdhC C succinate dehydrogenase
NMFLEBOF_02990 1.2e-79 yslB S Protein of unknown function (DUF2507)
NMFLEBOF_02991 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
NMFLEBOF_02992 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NMFLEBOF_02993 2e-52 trxA O Belongs to the thioredoxin family
NMFLEBOF_02994 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
NMFLEBOF_02996 7.9e-177 etfA C Electron transfer flavoprotein
NMFLEBOF_02997 4.5e-135 etfB C Electron transfer flavoprotein
NMFLEBOF_02998 4.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
NMFLEBOF_02999 4e-99 fadR K Transcriptional regulator
NMFLEBOF_03000 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
NMFLEBOF_03001 7.3e-68 yshE S membrane
NMFLEBOF_03002 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NMFLEBOF_03003 0.0 polX L COG1796 DNA polymerase IV (family X)
NMFLEBOF_03004 1.3e-85 cvpA S membrane protein, required for colicin V production
NMFLEBOF_03005 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NMFLEBOF_03006 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NMFLEBOF_03007 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMFLEBOF_03008 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NMFLEBOF_03009 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NMFLEBOF_03010 2.6e-32 sspI S Belongs to the SspI family
NMFLEBOF_03011 6.3e-207 ysfB KT regulator
NMFLEBOF_03012 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
NMFLEBOF_03013 2.6e-255 glcF C Glycolate oxidase
NMFLEBOF_03014 1e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
NMFLEBOF_03015 0.0 cstA T Carbon starvation protein
NMFLEBOF_03016 8.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
NMFLEBOF_03017 1.7e-143 araQ G transport system permease
NMFLEBOF_03018 1.2e-166 araP G carbohydrate transport
NMFLEBOF_03019 7.6e-252 araN G carbohydrate transport
NMFLEBOF_03020 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
NMFLEBOF_03021 3.7e-48 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NMFLEBOF_03022 3.9e-69 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
NMFLEBOF_03023 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
NMFLEBOF_03024 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
NMFLEBOF_03025 1.3e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
NMFLEBOF_03026 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMFLEBOF_03027 2.9e-204 ysdC G COG1363 Cellulase M and related proteins
NMFLEBOF_03028 9.2e-68 ysdB S Sigma-w pathway protein YsdB
NMFLEBOF_03029 9.8e-35 ysdA S Membrane
NMFLEBOF_03030 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NMFLEBOF_03031 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NMFLEBOF_03032 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NMFLEBOF_03034 2.7e-110 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMFLEBOF_03035 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
NMFLEBOF_03036 7e-130 lytT T COG3279 Response regulator of the LytR AlgR family
NMFLEBOF_03037 0.0 lytS 2.7.13.3 T Histidine kinase
NMFLEBOF_03038 2.8e-148 ysaA S HAD-hyrolase-like
NMFLEBOF_03039 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMFLEBOF_03041 9.3e-158 ytxC S YtxC-like family
NMFLEBOF_03042 4.9e-111 ytxB S SNARE associated Golgi protein
NMFLEBOF_03043 6.6e-173 dnaI L Primosomal protein DnaI
NMFLEBOF_03044 2.2e-265 dnaB L Membrane attachment protein
NMFLEBOF_03045 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NMFLEBOF_03046 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
NMFLEBOF_03047 1.8e-192 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMFLEBOF_03048 6.4e-66 ytcD K Transcriptional regulator
NMFLEBOF_03049 1.6e-200 ytbD EGP Major facilitator Superfamily
NMFLEBOF_03050 8.9e-161 ytbE S reductase
NMFLEBOF_03051 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NMFLEBOF_03052 1.1e-107 ytaF P Probably functions as a manganese efflux pump
NMFLEBOF_03053 3.8e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NMFLEBOF_03054 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NMFLEBOF_03055 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
NMFLEBOF_03056 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_03057 9e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
NMFLEBOF_03058 1.8e-242 icd 1.1.1.42 C isocitrate
NMFLEBOF_03059 7.6e-208 citZ 2.3.3.1 C Belongs to the citrate synthase family
NMFLEBOF_03060 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03061 4.7e-71 yeaL S membrane
NMFLEBOF_03062 9.9e-192 ytvI S sporulation integral membrane protein YtvI
NMFLEBOF_03063 4.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
NMFLEBOF_03064 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NMFLEBOF_03065 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NMFLEBOF_03066 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
NMFLEBOF_03067 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NMFLEBOF_03068 2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
NMFLEBOF_03069 0.0 dnaE 2.7.7.7 L DNA polymerase
NMFLEBOF_03070 3.2e-56 ytrH S Sporulation protein YtrH
NMFLEBOF_03071 8.2e-69 ytrI
NMFLEBOF_03072 9.2e-29
NMFLEBOF_03073 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
NMFLEBOF_03074 2.4e-47 ytpI S YtpI-like protein
NMFLEBOF_03075 8e-241 ytoI K transcriptional regulator containing CBS domains
NMFLEBOF_03076 1.7e-130 ytkL S Belongs to the UPF0173 family
NMFLEBOF_03077 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_03079 6.4e-265 argH 4.3.2.1 E argininosuccinate lyase
NMFLEBOF_03080 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
NMFLEBOF_03081 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
NMFLEBOF_03082 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NMFLEBOF_03083 5.4e-165 ytxK 2.1.1.72 L DNA methylase
NMFLEBOF_03084 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NMFLEBOF_03085 1.5e-66 ytfJ S Sporulation protein YtfJ
NMFLEBOF_03086 9.6e-108 ytfI S Protein of unknown function (DUF2953)
NMFLEBOF_03087 1.5e-86 yteJ S RDD family
NMFLEBOF_03088 4.3e-178 sppA OU signal peptide peptidase SppA
NMFLEBOF_03089 1.6e-146 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NMFLEBOF_03091 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03092 0.0 ytcJ S amidohydrolase
NMFLEBOF_03093 3.8e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMFLEBOF_03094 1.9e-27 sspB S spore protein
NMFLEBOF_03095 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NMFLEBOF_03096 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
NMFLEBOF_03097 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
NMFLEBOF_03098 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NMFLEBOF_03099 1.7e-153 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
NMFLEBOF_03100 6.5e-108 yttP K Transcriptional regulator
NMFLEBOF_03101 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
NMFLEBOF_03102 1.7e-307 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
NMFLEBOF_03103 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NMFLEBOF_03105 1.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMFLEBOF_03106 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
NMFLEBOF_03107 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
NMFLEBOF_03108 1.3e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
NMFLEBOF_03109 8e-224 acuC BQ histone deacetylase
NMFLEBOF_03110 1.4e-125 motS N Flagellar motor protein
NMFLEBOF_03111 7.1e-147 motA N flagellar motor
NMFLEBOF_03112 1.7e-182 ccpA K catabolite control protein A
NMFLEBOF_03113 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
NMFLEBOF_03114 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
NMFLEBOF_03115 6.6e-17 ytxH S COG4980 Gas vesicle protein
NMFLEBOF_03116 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NMFLEBOF_03117 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NMFLEBOF_03118 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
NMFLEBOF_03119 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NMFLEBOF_03120 9.8e-149 ytpQ S Belongs to the UPF0354 family
NMFLEBOF_03121 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NMFLEBOF_03122 6.7e-48 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NMFLEBOF_03123 3.5e-21 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
NMFLEBOF_03124 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
NMFLEBOF_03125 2.2e-51 ytzB S small secreted protein
NMFLEBOF_03126 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
NMFLEBOF_03127 1.3e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
NMFLEBOF_03128 1.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NMFLEBOF_03129 2e-45 ytzH S YtzH-like protein
NMFLEBOF_03130 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
NMFLEBOF_03131 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
NMFLEBOF_03132 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NMFLEBOF_03133 2.2e-165 ytlQ
NMFLEBOF_03134 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
NMFLEBOF_03135 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
NMFLEBOF_03136 3.9e-270 pepV 3.5.1.18 E Dipeptidase
NMFLEBOF_03137 2.1e-225 pbuO S permease
NMFLEBOF_03138 7.8e-200 ythQ U Bacterial ABC transporter protein EcsB
NMFLEBOF_03139 1.4e-130 ythP V ABC transporter
NMFLEBOF_03140 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
NMFLEBOF_03141 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NMFLEBOF_03142 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_03143 8.2e-232 ytfP S HI0933-like protein
NMFLEBOF_03144 3.6e-137 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NMFLEBOF_03145 7.2e-130 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
NMFLEBOF_03146 3.1e-26 yteV S Sporulation protein Cse60
NMFLEBOF_03147 4e-58 yteU S Integral membrane protein
NMFLEBOF_03148 9e-248 yteT S Oxidoreductase family, C-terminal alpha/beta domain
NMFLEBOF_03149 3.9e-72 yteS G transport
NMFLEBOF_03150 6.6e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
NMFLEBOF_03151 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
NMFLEBOF_03152 1.4e-163 ytdP K Transcriptional regulator
NMFLEBOF_03153 1.2e-62 ytdP K Transcriptional regulator
NMFLEBOF_03154 3.3e-135 ytdP K Transcriptional regulator
NMFLEBOF_03155 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
NMFLEBOF_03156 8.2e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
NMFLEBOF_03157 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
NMFLEBOF_03158 1e-218 bioI 1.14.14.46 C Cytochrome P450
NMFLEBOF_03159 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NMFLEBOF_03160 1.5e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NMFLEBOF_03161 3.1e-212 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMFLEBOF_03162 2.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
NMFLEBOF_03163 1.8e-118 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
NMFLEBOF_03164 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
NMFLEBOF_03165 2.8e-188 msmR K Transcriptional regulator
NMFLEBOF_03166 1.4e-242 msmE G Bacterial extracellular solute-binding protein
NMFLEBOF_03167 6.2e-168 amyD P ABC transporter
NMFLEBOF_03168 4.4e-144 amyC P ABC transporter (permease)
NMFLEBOF_03169 1.5e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
NMFLEBOF_03170 2.1e-51 ytwF P Sulfurtransferase
NMFLEBOF_03171 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NMFLEBOF_03172 7.7e-55 ytvB S Protein of unknown function (DUF4257)
NMFLEBOF_03173 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
NMFLEBOF_03174 1.3e-210 yttB EGP Major facilitator Superfamily
NMFLEBOF_03175 4.8e-23 yttA 2.7.13.3 S Pfam Transposase IS66
NMFLEBOF_03176 1.2e-238 L COG3328 Transposase and inactivated derivatives
NMFLEBOF_03177 2.5e-311 bceB V ABC transporter (permease)
NMFLEBOF_03178 1.1e-138 bceA V ABC transporter, ATP-binding protein
NMFLEBOF_03179 1.6e-185 T PhoQ Sensor
NMFLEBOF_03180 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_03181 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMFLEBOF_03182 9.1e-127 ytrE V ABC transporter, ATP-binding protein
NMFLEBOF_03183 3.3e-151
NMFLEBOF_03184 8.3e-158 P ABC-2 family transporter protein
NMFLEBOF_03185 4.2e-161 ytrB P abc transporter atp-binding protein
NMFLEBOF_03186 5.1e-66 ytrA K GntR family transcriptional regulator
NMFLEBOF_03188 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03189 6.7e-41 ytzC S Protein of unknown function (DUF2524)
NMFLEBOF_03190 2.1e-190 yhcC S Fe-S oxidoreductase
NMFLEBOF_03191 9.7e-106 ytqB J Putative rRNA methylase
NMFLEBOF_03192 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
NMFLEBOF_03193 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
NMFLEBOF_03194 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NMFLEBOF_03195 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_03196 0.0 asnB 6.3.5.4 E Asparagine synthase
NMFLEBOF_03197 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NMFLEBOF_03198 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NMFLEBOF_03199 1.7e-37 ytmB S Protein of unknown function (DUF2584)
NMFLEBOF_03200 7.2e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
NMFLEBOF_03201 1.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
NMFLEBOF_03202 1.4e-144 ytlC P ABC transporter
NMFLEBOF_03203 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
NMFLEBOF_03204 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
NMFLEBOF_03205 1.7e-61 ytkC S Bacteriophage holin family
NMFLEBOF_03206 2.1e-76 dps P Belongs to the Dps family
NMFLEBOF_03208 1.1e-72 ytkA S YtkA-like
NMFLEBOF_03209 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NMFLEBOF_03210 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMFLEBOF_03211 3.6e-41 rpmE2 J Ribosomal protein L31
NMFLEBOF_03212 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
NMFLEBOF_03213 2.4e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
NMFLEBOF_03214 1.1e-24 S Domain of Unknown Function (DUF1540)
NMFLEBOF_03215 6.8e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
NMFLEBOF_03216 1.4e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
NMFLEBOF_03217 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
NMFLEBOF_03218 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
NMFLEBOF_03219 1.2e-213 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
NMFLEBOF_03220 5.9e-277 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
NMFLEBOF_03221 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NMFLEBOF_03222 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
NMFLEBOF_03223 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NMFLEBOF_03224 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
NMFLEBOF_03225 9.7e-132 dksA T COG1734 DnaK suppressor protein
NMFLEBOF_03226 1.5e-152 galU 2.7.7.9 M Nucleotidyl transferase
NMFLEBOF_03227 4.4e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMFLEBOF_03228 2.2e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
NMFLEBOF_03229 8.4e-229 ytcC M Glycosyltransferase Family 4
NMFLEBOF_03231 3.7e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
NMFLEBOF_03232 1.1e-214 cotSA M Glycosyl transferases group 1
NMFLEBOF_03233 2.2e-204 cotI S Spore coat protein
NMFLEBOF_03234 6.6e-73 tspO T membrane
NMFLEBOF_03235 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
NMFLEBOF_03236 3.9e-281 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
NMFLEBOF_03237 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
NMFLEBOF_03238 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NMFLEBOF_03239 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NMFLEBOF_03248 7.8e-08
NMFLEBOF_03249 1.3e-09
NMFLEBOF_03256 2e-08
NMFLEBOF_03261 3.4e-39 S COG NOG14552 non supervised orthologous group
NMFLEBOF_03262 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
NMFLEBOF_03263 1.9e-92 M1-753 M FR47-like protein
NMFLEBOF_03264 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
NMFLEBOF_03265 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
NMFLEBOF_03266 3.3e-83 yuaE S DinB superfamily
NMFLEBOF_03267 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03268 8.1e-105 yuaD
NMFLEBOF_03269 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
NMFLEBOF_03270 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
NMFLEBOF_03271 5.5e-95 yuaC K Belongs to the GbsR family
NMFLEBOF_03272 2.2e-91 yuaB
NMFLEBOF_03273 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
NMFLEBOF_03274 1.6e-236 ktrB P Potassium
NMFLEBOF_03275 1e-38 yiaA S yiaA/B two helix domain
NMFLEBOF_03276 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMFLEBOF_03277 2.3e-271 yubD P Major Facilitator Superfamily
NMFLEBOF_03278 9.3e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
NMFLEBOF_03280 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
NMFLEBOF_03281 1.3e-194 yubA S transporter activity
NMFLEBOF_03282 3.3e-183 ygjR S Oxidoreductase
NMFLEBOF_03283 7.5e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
NMFLEBOF_03284 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
NMFLEBOF_03285 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
NMFLEBOF_03286 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
NMFLEBOF_03287 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
NMFLEBOF_03288 6.8e-129 mcpA NT chemotaxis protein
NMFLEBOF_03289 7.8e-94 mcpA NT chemotaxis protein
NMFLEBOF_03290 8.5e-295 mcpA NT chemotaxis protein
NMFLEBOF_03291 1.1e-201 mcpA NT chemotaxis protein
NMFLEBOF_03292 7.1e-225 mcpA NT chemotaxis protein
NMFLEBOF_03293 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
NMFLEBOF_03294 1e-35
NMFLEBOF_03295 3.6e-304 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
NMFLEBOF_03296 4.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
NMFLEBOF_03297 1.4e-116 yugP S Zn-dependent protease
NMFLEBOF_03298 3.7e-36
NMFLEBOF_03299 5.4e-53 mstX S Membrane-integrating protein Mistic
NMFLEBOF_03300 3.1e-181 yugO P COG1226 Kef-type K transport systems
NMFLEBOF_03301 1.7e-69 yugN S YugN-like family
NMFLEBOF_03303 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
NMFLEBOF_03304 1.9e-225 yugK C Dehydrogenase
NMFLEBOF_03305 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
NMFLEBOF_03306 1.1e-34 yuzA S Domain of unknown function (DUF378)
NMFLEBOF_03307 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
NMFLEBOF_03308 2.1e-199 yugH 2.6.1.1 E Aminotransferase
NMFLEBOF_03309 1.6e-85 alaR K Transcriptional regulator
NMFLEBOF_03310 1.4e-155 yugF I Hydrolase
NMFLEBOF_03311 4.6e-39 yugE S Domain of unknown function (DUF1871)
NMFLEBOF_03312 2.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
NMFLEBOF_03313 1.7e-232 T PhoQ Sensor
NMFLEBOF_03314 1.8e-68 kapB G Kinase associated protein B
NMFLEBOF_03315 4.2e-115 kapD L the KinA pathway to sporulation
NMFLEBOF_03317 3.8e-185 yuxJ EGP Major facilitator Superfamily
NMFLEBOF_03318 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
NMFLEBOF_03319 1.8e-74 yuxK S protein conserved in bacteria
NMFLEBOF_03320 6.3e-78 yufK S Family of unknown function (DUF5366)
NMFLEBOF_03321 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
NMFLEBOF_03322 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
NMFLEBOF_03323 3.4e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
NMFLEBOF_03324 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
NMFLEBOF_03325 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
NMFLEBOF_03326 4.3e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
NMFLEBOF_03327 1.3e-233 maeN C COG3493 Na citrate symporter
NMFLEBOF_03328 3.2e-14
NMFLEBOF_03329 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
NMFLEBOF_03330 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMFLEBOF_03331 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMFLEBOF_03332 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMFLEBOF_03333 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMFLEBOF_03334 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
NMFLEBOF_03335 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
NMFLEBOF_03336 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
NMFLEBOF_03337 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_03338 0.0 comP 2.7.13.3 T Histidine kinase
NMFLEBOF_03340 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
NMFLEBOF_03343 3.2e-22 yuzC
NMFLEBOF_03344 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
NMFLEBOF_03345 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NMFLEBOF_03346 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
NMFLEBOF_03347 1.8e-66 yueI S Protein of unknown function (DUF1694)
NMFLEBOF_03348 7.4e-39 yueH S YueH-like protein
NMFLEBOF_03349 2.5e-30 yueG S Spore germination protein gerPA/gerPF
NMFLEBOF_03350 3.2e-190 yueF S transporter activity
NMFLEBOF_03351 5.2e-71 S Protein of unknown function (DUF2283)
NMFLEBOF_03352 2.2e-24 S Protein of unknown function (DUF2642)
NMFLEBOF_03353 1.1e-95 yueE S phosphohydrolase
NMFLEBOF_03354 5.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_03355 2.9e-66 yueC S Family of unknown function (DUF5383)
NMFLEBOF_03356 0.0 esaA S type VII secretion protein EsaA
NMFLEBOF_03357 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
NMFLEBOF_03358 2.4e-208 essB S WXG100 protein secretion system (Wss), protein YukC
NMFLEBOF_03359 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
NMFLEBOF_03360 2.8e-45 esxA S Belongs to the WXG100 family
NMFLEBOF_03361 1.5e-228 yukF QT Transcriptional regulator
NMFLEBOF_03362 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
NMFLEBOF_03363 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
NMFLEBOF_03364 5e-36 mbtH S MbtH-like protein
NMFLEBOF_03365 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_03366 5.8e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
NMFLEBOF_03367 1.6e-310 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
NMFLEBOF_03368 1.6e-224 entC 5.4.4.2 HQ Isochorismate synthase
NMFLEBOF_03369 8.1e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_03370 3.9e-167 besA S Putative esterase
NMFLEBOF_03371 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
NMFLEBOF_03372 1.1e-93 bioY S Biotin biosynthesis protein
NMFLEBOF_03373 3.9e-211 yuiF S antiporter
NMFLEBOF_03374 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NMFLEBOF_03375 1.2e-77 yuiD S protein conserved in bacteria
NMFLEBOF_03376 8.9e-116 yuiC S protein conserved in bacteria
NMFLEBOF_03377 1.1e-26 yuiB S Putative membrane protein
NMFLEBOF_03378 3.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
NMFLEBOF_03379 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
NMFLEBOF_03381 1.1e-183 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NMFLEBOF_03382 7.7e-99 paiB K Putative FMN-binding domain
NMFLEBOF_03383 3.7e-63 erpA S Belongs to the HesB IscA family
NMFLEBOF_03384 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NMFLEBOF_03385 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMFLEBOF_03386 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03388 3.2e-39 yuzB S Belongs to the UPF0349 family
NMFLEBOF_03389 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
NMFLEBOF_03390 1.1e-55 yuzD S protein conserved in bacteria
NMFLEBOF_03391 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
NMFLEBOF_03392 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
NMFLEBOF_03393 4.3e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NMFLEBOF_03394 1.2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NMFLEBOF_03395 6e-241 hom 1.1.1.3 E homoserine dehydrogenase
NMFLEBOF_03396 5.6e-126 yutH S Spore coat protein
NMFLEBOF_03397 1.2e-45 yutH S Spore coat protein
NMFLEBOF_03398 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
NMFLEBOF_03399 4.2e-141 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NMFLEBOF_03400 2.5e-74 yutE S Protein of unknown function DUF86
NMFLEBOF_03401 9.7e-48 yutD S protein conserved in bacteria
NMFLEBOF_03402 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
NMFLEBOF_03403 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NMFLEBOF_03404 1.7e-195 lytH M Peptidase, M23
NMFLEBOF_03405 1e-131 yunB S Sporulation protein YunB (Spo_YunB)
NMFLEBOF_03406 4.1e-47 yunC S Domain of unknown function (DUF1805)
NMFLEBOF_03407 1.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NMFLEBOF_03408 1.3e-140 yunE S membrane transporter protein
NMFLEBOF_03409 4.3e-171 yunF S Protein of unknown function DUF72
NMFLEBOF_03410 2.8e-60 yunG
NMFLEBOF_03411 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
NMFLEBOF_03412 3.5e-299 pucR QT COG2508 Regulator of polyketide synthase expression
NMFLEBOF_03413 1.1e-234 pbuX F Permease family
NMFLEBOF_03414 1.9e-215 pbuX F xanthine
NMFLEBOF_03415 3.7e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
NMFLEBOF_03416 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
NMFLEBOF_03419 1.4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
NMFLEBOF_03420 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
NMFLEBOF_03421 4.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
NMFLEBOF_03422 1.3e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
NMFLEBOF_03423 6.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NMFLEBOF_03424 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
NMFLEBOF_03425 6.4e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
NMFLEBOF_03426 2.7e-168 bsn L Ribonuclease
NMFLEBOF_03427 2.9e-204 msmX P Belongs to the ABC transporter superfamily
NMFLEBOF_03428 3.3e-135 yurK K UTRA
NMFLEBOF_03429 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
NMFLEBOF_03430 6.7e-84 yurM P COG0395 ABC-type sugar transport system, permease component
NMFLEBOF_03431 4.6e-70 yurM P COG0395 ABC-type sugar transport system, permease component
NMFLEBOF_03432 1.5e-155 yurN G Binding-protein-dependent transport system inner membrane component
NMFLEBOF_03433 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
NMFLEBOF_03434 5.1e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
NMFLEBOF_03435 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
NMFLEBOF_03436 9.3e-206 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
NMFLEBOF_03438 1e-41
NMFLEBOF_03439 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_03440 3.2e-45 L transposase activity
NMFLEBOF_03441 5.5e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_03442 3.6e-42 K helix_turn_helix, Arsenical Resistance Operon Repressor
NMFLEBOF_03443 4.2e-08
NMFLEBOF_03444 2.1e-12
NMFLEBOF_03445 1.2e-297 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
NMFLEBOF_03446 1.4e-83 S SMI1-KNR4 cell-wall
NMFLEBOF_03447 1.9e-111 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_03448 4.6e-57 S Bacteriophage holin family
NMFLEBOF_03450 1.1e-15
NMFLEBOF_03451 8.9e-178 S Domain of unknown function (DUF2479)
NMFLEBOF_03452 1.9e-260
NMFLEBOF_03453 3.4e-112 mur1 NU Prophage endopeptidase tail
NMFLEBOF_03454 2.7e-45 S Phage tail protein
NMFLEBOF_03455 2.7e-294 D Phage tail tape measure protein
NMFLEBOF_03458 3.1e-27 S Pfam:Phage_TTP_1
NMFLEBOF_03459 1.2e-09
NMFLEBOF_03460 4.9e-29 S Bacteriophage HK97-gp10, putative tail-component
NMFLEBOF_03461 1e-27 S Phage head-tail joining protein
NMFLEBOF_03462 5.7e-22 S Phage gp6-like head-tail connector protein
NMFLEBOF_03463 3e-07
NMFLEBOF_03464 1.5e-129 S capsid protein
NMFLEBOF_03465 4.2e-72 pi136 S Caudovirus prohead serine protease
NMFLEBOF_03466 1.3e-171 S portal protein
NMFLEBOF_03468 1.6e-148 terL S Terminase
NMFLEBOF_03469 6e-56 terS L Terminase, small subunit
NMFLEBOF_03471 5e-18 S HNH endonuclease
NMFLEBOF_03475 2.6e-73 L Phage integrase family
NMFLEBOF_03476 7.4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
NMFLEBOF_03480 5e-07
NMFLEBOF_03481 2.6e-49 S dUTPase
NMFLEBOF_03484 6.9e-26
NMFLEBOF_03490 1.1e-31
NMFLEBOF_03492 2.4e-52 dnaC L DNA replication protein
NMFLEBOF_03493 3.6e-69 L dnaD_dom DnaD domain protein
NMFLEBOF_03495 9.9e-16
NMFLEBOF_03497 5e-45 K Helix-turn-helix XRE-family like proteins
NMFLEBOF_03500 9.5e-44
NMFLEBOF_03501 1e-118 int L Belongs to the 'phage' integrase family
NMFLEBOF_03502 3.5e-271 sufB O FeS cluster assembly
NMFLEBOF_03503 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
NMFLEBOF_03504 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NMFLEBOF_03505 9.1e-245 sufD O assembly protein SufD
NMFLEBOF_03506 8.6e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
NMFLEBOF_03507 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NMFLEBOF_03508 6.1e-146 metQ P Belongs to the NlpA lipoprotein family
NMFLEBOF_03509 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
NMFLEBOF_03510 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NMFLEBOF_03511 3.2e-56 yusD S SCP-2 sterol transfer family
NMFLEBOF_03512 1.2e-54 traF CO Thioredoxin
NMFLEBOF_03513 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
NMFLEBOF_03514 2.4e-39 yusG S Protein of unknown function (DUF2553)
NMFLEBOF_03515 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
NMFLEBOF_03516 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
NMFLEBOF_03517 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
NMFLEBOF_03518 1.6e-216 fadA 2.3.1.16 I Belongs to the thiolase family
NMFLEBOF_03519 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
NMFLEBOF_03520 8.1e-09 S YuzL-like protein
NMFLEBOF_03521 1.2e-163 fadM E Proline dehydrogenase
NMFLEBOF_03522 5.1e-40
NMFLEBOF_03523 5.4e-53 yusN M Coat F domain
NMFLEBOF_03524 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
NMFLEBOF_03525 6.1e-291 yusP P Major facilitator superfamily
NMFLEBOF_03526 2.1e-48 yusQ S Tautomerase enzyme
NMFLEBOF_03527 3.8e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_03528 8.2e-157 yusT K LysR substrate binding domain
NMFLEBOF_03529 5.6e-39 yusU S Protein of unknown function (DUF2573)
NMFLEBOF_03530 3.9e-153 yusV 3.6.3.34 HP ABC transporter
NMFLEBOF_03531 2.5e-66 S YusW-like protein
NMFLEBOF_03532 2.7e-300 pepF2 E COG1164 Oligoendopeptidase F
NMFLEBOF_03534 1.3e-23 ecsB U ABC transporter
NMFLEBOF_03535 2.2e-75 ecsA V ABC superfamily ATP binding cassette transporter ABC protein
NMFLEBOF_03536 1.1e-25 Q methyltransferase
NMFLEBOF_03537 8.6e-27 EGP Major facilitator Superfamily
NMFLEBOF_03538 7.1e-07 K PFAM Acetyltransferase (GNAT) family
NMFLEBOF_03539 6.4e-36 2.6.1.76 E Psort location Cytoplasmic, score
NMFLEBOF_03540 2.4e-19 S Evidence 4 Homologs of previously reported genes of
NMFLEBOF_03541 1.1e-24
NMFLEBOF_03542 1.2e-129 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
NMFLEBOF_03543 1.4e-136 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_03544 8e-79 dps P Ferritin-like domain
NMFLEBOF_03546 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03547 1.5e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMFLEBOF_03548 5.7e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_03549 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
NMFLEBOF_03550 4.3e-158 yuxN K Transcriptional regulator
NMFLEBOF_03551 5.6e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NMFLEBOF_03552 1.1e-23 S Protein of unknown function (DUF3970)
NMFLEBOF_03553 1e-244 gerAA EG Spore germination protein
NMFLEBOF_03554 3.8e-196 gerAB E Spore germination protein
NMFLEBOF_03555 2e-176 gerAC S Spore germination B3/ GerAC like, C-terminal
NMFLEBOF_03556 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_03557 1.6e-186 vraS 2.7.13.3 T Histidine kinase
NMFLEBOF_03558 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
NMFLEBOF_03559 3.1e-116 liaG S Putative adhesin
NMFLEBOF_03560 1.1e-103 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
NMFLEBOF_03561 7.3e-62 liaI S membrane
NMFLEBOF_03562 5.9e-225 yvqJ EGP Major facilitator Superfamily
NMFLEBOF_03563 3.9e-99 yvqK 2.5.1.17 S Adenosyltransferase
NMFLEBOF_03564 2.1e-244 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
NMFLEBOF_03565 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_03566 6.9e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
NMFLEBOF_03567 2.6e-138 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_03568 4.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
NMFLEBOF_03569 0.0 T PhoQ Sensor
NMFLEBOF_03570 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_03571 3.6e-22
NMFLEBOF_03572 2.3e-96 yvrI K RNA polymerase
NMFLEBOF_03573 2.4e-19 S YvrJ protein family
NMFLEBOF_03574 4.7e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
NMFLEBOF_03575 1.3e-64 yvrL S Regulatory protein YrvL
NMFLEBOF_03576 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
NMFLEBOF_03577 1.6e-123 macB V ABC transporter, ATP-binding protein
NMFLEBOF_03578 2e-174 M Efflux transporter rnd family, mfp subunit
NMFLEBOF_03579 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
NMFLEBOF_03580 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_03581 1.1e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NMFLEBOF_03582 7.6e-177 fhuD P ABC transporter
NMFLEBOF_03584 1.8e-235 yvsH E Arginine ornithine antiporter
NMFLEBOF_03585 6.5e-16 S Small spore protein J (Spore_SspJ)
NMFLEBOF_03586 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
NMFLEBOF_03587 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
NMFLEBOF_03588 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
NMFLEBOF_03589 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
NMFLEBOF_03590 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
NMFLEBOF_03591 1.1e-155 yvgN S reductase
NMFLEBOF_03592 2.1e-85 yvgO
NMFLEBOF_03593 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
NMFLEBOF_03594 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
NMFLEBOF_03595 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NMFLEBOF_03596 0.0 helD 3.6.4.12 L DNA helicase
NMFLEBOF_03598 2e-106 yvgT S membrane
NMFLEBOF_03599 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
NMFLEBOF_03600 1.6e-104 bdbD O Thioredoxin
NMFLEBOF_03601 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
NMFLEBOF_03603 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03604 0.0 copA 3.6.3.54 P P-type ATPase
NMFLEBOF_03605 5.9e-29 copZ P Copper resistance protein CopZ
NMFLEBOF_03606 2.2e-48 csoR S transcriptional
NMFLEBOF_03607 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
NMFLEBOF_03608 1.1e-68 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMFLEBOF_03609 1.4e-18 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NMFLEBOF_03610 0.0 yvaC S Fusaric acid resistance protein-like
NMFLEBOF_03611 8.2e-72 yvaD S Family of unknown function (DUF5360)
NMFLEBOF_03612 3.1e-54 yvaE P Small Multidrug Resistance protein
NMFLEBOF_03613 4.1e-101 K Bacterial regulatory proteins, tetR family
NMFLEBOF_03614 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_03615 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03618 3.6e-12
NMFLEBOF_03619 2.1e-179 A Pre-toxin TG
NMFLEBOF_03620 2.4e-07 S Immunity protein 50
NMFLEBOF_03622 1.2e-110 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
NMFLEBOF_03623 4.6e-57 S Bacteriophage holin family
NMFLEBOF_03625 1.1e-15
NMFLEBOF_03626 8.9e-178 S Domain of unknown function (DUF2479)
NMFLEBOF_03627 2.3e-263
NMFLEBOF_03628 7.2e-242 NU Prophage endopeptidase tail
NMFLEBOF_03629 2.2e-111 S Phage tail protein
NMFLEBOF_03630 0.0 S peptidoglycan catabolic process
NMFLEBOF_03631 4.8e-10
NMFLEBOF_03632 2e-26
NMFLEBOF_03633 1.5e-61
NMFLEBOF_03634 1.9e-30
NMFLEBOF_03635 2.3e-47 S Bacteriophage HK97-gp10, putative tail-component
NMFLEBOF_03636 1.1e-24 S Phage gp6-like head-tail connector protein
NMFLEBOF_03637 1.3e-26 S peptidoglycan catabolic process
NMFLEBOF_03639 1.9e-180 S capsid protein
NMFLEBOF_03640 1e-105 S peptidase activity
NMFLEBOF_03641 2.7e-214 S Phage portal protein
NMFLEBOF_03642 2.2e-10
NMFLEBOF_03643 1.9e-218 S Phage Terminase
NMFLEBOF_03644 4.6e-70 S Phage terminase, small subunit
NMFLEBOF_03645 3.8e-08
NMFLEBOF_03646 2.2e-59 S HNH endonuclease
NMFLEBOF_03648 7.9e-21
NMFLEBOF_03649 2.3e-15 S PIN domain
NMFLEBOF_03651 2.6e-73 L Phage integrase family
NMFLEBOF_03652 7.4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
NMFLEBOF_03654 3.8e-11 S YopX protein
NMFLEBOF_03656 1.1e-46 S dUTPase
NMFLEBOF_03658 6.9e-26
NMFLEBOF_03661 2e-07 yqaO S Phage-like element PBSX protein XtrA
NMFLEBOF_03665 1.9e-31
NMFLEBOF_03666 2e-43 dnaC L IstB-like ATP binding protein
NMFLEBOF_03667 9e-71 ybl78 L Conserved phage C-terminus (Phg_2220_C)
NMFLEBOF_03669 8.6e-11 S sequence-specific DNA binding
NMFLEBOF_03670 3.6e-07 acoR T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
NMFLEBOF_03671 2.5e-44 K Helix-turn-helix XRE-family like proteins
NMFLEBOF_03673 2.8e-59
NMFLEBOF_03674 3.1e-34 S Phage integrase family
NMFLEBOF_03675 4.5e-66 S Phage integrase family
NMFLEBOF_03677 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NMFLEBOF_03678 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NMFLEBOF_03679 5.6e-143 est 3.1.1.1 S Carboxylesterase
NMFLEBOF_03680 2.4e-23 secG U Preprotein translocase subunit SecG
NMFLEBOF_03681 1.5e-151 yvaM S Serine aminopeptidase, S33
NMFLEBOF_03682 9.8e-36 yvzC K Transcriptional
NMFLEBOF_03683 3.1e-69 K transcriptional
NMFLEBOF_03684 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
NMFLEBOF_03685 2.2e-54 yodB K transcriptional
NMFLEBOF_03686 3e-216 NT chemotaxis protein
NMFLEBOF_03687 5.8e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMFLEBOF_03688 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMFLEBOF_03689 7.3e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMFLEBOF_03690 6.3e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMFLEBOF_03691 1.9e-60 yvbF K Belongs to the GbsR family
NMFLEBOF_03692 4.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMFLEBOF_03693 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
NMFLEBOF_03694 1.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
NMFLEBOF_03695 4.4e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
NMFLEBOF_03696 3.5e-97 yvbF K Belongs to the GbsR family
NMFLEBOF_03697 6e-101 yvbG U UPF0056 membrane protein
NMFLEBOF_03698 5.6e-112 yvbH S YvbH-like oligomerisation region
NMFLEBOF_03699 2.6e-121 exoY M Membrane
NMFLEBOF_03700 0.0 tcaA S response to antibiotic
NMFLEBOF_03701 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
NMFLEBOF_03702 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NMFLEBOF_03703 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
NMFLEBOF_03704 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NMFLEBOF_03705 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NMFLEBOF_03706 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NMFLEBOF_03707 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMFLEBOF_03708 1.6e-252 araE EGP Major facilitator Superfamily
NMFLEBOF_03709 5.5e-203 araR K transcriptional
NMFLEBOF_03710 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMFLEBOF_03711 1.1e-158 yvbU K Transcriptional regulator
NMFLEBOF_03712 1.2e-155 yvbV EG EamA-like transporter family
NMFLEBOF_03713 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
NMFLEBOF_03714 2.6e-146 yvbX S Glycosyl hydrolase
NMFLEBOF_03715 7.5e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMFLEBOF_03716 7.8e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
NMFLEBOF_03717 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
NMFLEBOF_03718 1.3e-44 S Protein of unknown function (DUF2812)
NMFLEBOF_03719 2.6e-31 K Transcriptional regulator PadR-like family
NMFLEBOF_03720 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_03721 1.3e-196 desK 2.7.13.3 T Histidine kinase
NMFLEBOF_03722 2e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
NMFLEBOF_03723 8.9e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
NMFLEBOF_03724 1.7e-156 rsbQ S Alpha/beta hydrolase family
NMFLEBOF_03725 7.2e-196 rsbU 3.1.3.3 T response regulator
NMFLEBOF_03726 1.9e-250 galA 3.2.1.89 G arabinogalactan
NMFLEBOF_03727 0.0 lacA 3.2.1.23 G beta-galactosidase
NMFLEBOF_03728 7.2e-150 ganQ P transport
NMFLEBOF_03729 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
NMFLEBOF_03730 3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
NMFLEBOF_03731 1.4e-184 lacR K Transcriptional regulator
NMFLEBOF_03732 2.7e-113 yvfI K COG2186 Transcriptional regulators
NMFLEBOF_03733 5.3e-306 yvfH C L-lactate permease
NMFLEBOF_03734 2.3e-113 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NMFLEBOF_03735 3.8e-94 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
NMFLEBOF_03736 1e-31 yvfG S YvfG protein
NMFLEBOF_03737 2.2e-187 yvfF GM Exopolysaccharide biosynthesis protein
NMFLEBOF_03738 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
NMFLEBOF_03739 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
NMFLEBOF_03740 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMFLEBOF_03741 4.3e-254 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_03742 3.6e-188 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
NMFLEBOF_03743 3.5e-202 epsI GM pyruvyl transferase
NMFLEBOF_03744 2.4e-192 epsH GT2 S Glycosyltransferase like family 2
NMFLEBOF_03745 1.8e-206 epsG S EpsG family
NMFLEBOF_03746 8.4e-218 epsF GT4 M Glycosyl transferases group 1
NMFLEBOF_03747 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
NMFLEBOF_03748 5.2e-220 epsD GT4 M Glycosyl transferase 4-like
NMFLEBOF_03749 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
NMFLEBOF_03750 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
NMFLEBOF_03751 4e-122 ywqC M biosynthesis protein
NMFLEBOF_03752 3.1e-75 slr K transcriptional
NMFLEBOF_03753 2.8e-279 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
NMFLEBOF_03755 4.6e-93 padC Q Phenolic acid decarboxylase
NMFLEBOF_03756 7.3e-46 MA20_18690 S Protein of unknown function (DUF3237)
NMFLEBOF_03757 6.1e-16 MA20_18690 S Protein of unknown function (DUF3237)
NMFLEBOF_03758 2.9e-58 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMFLEBOF_03759 9.4e-55 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NMFLEBOF_03760 1.2e-177 pbpE V Beta-lactamase
NMFLEBOF_03761 1.5e-63 pbpE V Beta-lactamase
NMFLEBOF_03762 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
NMFLEBOF_03763 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
NMFLEBOF_03764 1.8e-295 yveA E amino acid
NMFLEBOF_03765 7.4e-106 yvdT K Transcriptional regulator
NMFLEBOF_03766 1.5e-50 ykkC P Small Multidrug Resistance protein
NMFLEBOF_03767 7.1e-50 sugE P Small Multidrug Resistance protein
NMFLEBOF_03768 3.9e-72 yvdQ S Protein of unknown function (DUF3231)
NMFLEBOF_03770 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NMFLEBOF_03771 5e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
NMFLEBOF_03772 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
NMFLEBOF_03773 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
NMFLEBOF_03774 4.1e-156 malA S Protein of unknown function (DUF1189)
NMFLEBOF_03775 2.5e-147 malD P transport
NMFLEBOF_03776 5.5e-242 malC P COG1175 ABC-type sugar transport systems, permease components
NMFLEBOF_03777 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
NMFLEBOF_03778 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
NMFLEBOF_03779 8.8e-173 yvdE K Transcriptional regulator
NMFLEBOF_03780 4.7e-105 yvdD 3.2.2.10 S Belongs to the LOG family
NMFLEBOF_03781 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
NMFLEBOF_03782 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
NMFLEBOF_03783 7.4e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
NMFLEBOF_03784 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NMFLEBOF_03785 0.0 yxdM V ABC transporter (permease)
NMFLEBOF_03786 2.8e-140 yvcR V ABC transporter, ATP-binding protein
NMFLEBOF_03787 6.8e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
NMFLEBOF_03788 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_03789 5.5e-21
NMFLEBOF_03790 4e-144 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
NMFLEBOF_03791 1.6e-36 crh G Phosphocarrier protein Chr
NMFLEBOF_03792 4.1e-170 whiA K May be required for sporulation
NMFLEBOF_03793 3.6e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NMFLEBOF_03794 5.7e-166 rapZ S Displays ATPase and GTPase activities
NMFLEBOF_03795 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMFLEBOF_03796 2.8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NMFLEBOF_03797 1.1e-97 usp CBM50 M protein conserved in bacteria
NMFLEBOF_03798 8.4e-276 S COG0457 FOG TPR repeat
NMFLEBOF_03799 0.0 msbA2 3.6.3.44 V ABC transporter
NMFLEBOF_03801 0.0
NMFLEBOF_03802 4.9e-75
NMFLEBOF_03803 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
NMFLEBOF_03804 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
NMFLEBOF_03805 1.4e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NMFLEBOF_03806 8.1e-114 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NMFLEBOF_03807 6.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
NMFLEBOF_03808 3.4e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NMFLEBOF_03809 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
NMFLEBOF_03810 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NMFLEBOF_03811 4.5e-140 yvpB NU protein conserved in bacteria
NMFLEBOF_03812 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
NMFLEBOF_03813 1.4e-45 L transposase activity
NMFLEBOF_03814 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_03815 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
NMFLEBOF_03816 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
NMFLEBOF_03817 4.5e-161 yvoD P COG0370 Fe2 transport system protein B
NMFLEBOF_03818 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NMFLEBOF_03819 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NMFLEBOF_03820 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NMFLEBOF_03821 2.3e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NMFLEBOF_03822 3.6e-134 yvoA K transcriptional
NMFLEBOF_03823 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
NMFLEBOF_03825 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03826 1.2e-50 yvlD S Membrane
NMFLEBOF_03827 2.6e-26 pspB KT PspC domain
NMFLEBOF_03828 9.2e-166 yvlB S Putative adhesin
NMFLEBOF_03829 8e-49 yvlA
NMFLEBOF_03830 5.7e-33 yvkN
NMFLEBOF_03831 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMFLEBOF_03832 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NMFLEBOF_03833 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NMFLEBOF_03834 1.2e-30 csbA S protein conserved in bacteria
NMFLEBOF_03835 0.0 yvkC 2.7.9.2 GT Phosphotransferase
NMFLEBOF_03836 7e-101 yvkB K Transcriptional regulator
NMFLEBOF_03837 9.6e-226 yvkA EGP Major facilitator Superfamily
NMFLEBOF_03838 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMFLEBOF_03839 1.8e-72 swrA S Swarming motility protein
NMFLEBOF_03840 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
NMFLEBOF_03841 1.2e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
NMFLEBOF_03842 2.7e-123 ftsE D cell division ATP-binding protein FtsE
NMFLEBOF_03843 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
NMFLEBOF_03844 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
NMFLEBOF_03845 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NMFLEBOF_03846 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NMFLEBOF_03847 1.4e-45 L transposase activity
NMFLEBOF_03848 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_03849 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NMFLEBOF_03850 4.6e-51
NMFLEBOF_03851 1.9e-08 fliT S bacterial-type flagellum organization
NMFLEBOF_03852 1.9e-68 fliS N flagellar protein FliS
NMFLEBOF_03853 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NMFLEBOF_03854 1.2e-55 flaG N flagellar protein FlaG
NMFLEBOF_03855 1.4e-122 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NMFLEBOF_03856 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NMFLEBOF_03857 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NMFLEBOF_03858 1.3e-49 yviE
NMFLEBOF_03859 1.3e-154 flgL N Belongs to the bacterial flagellin family
NMFLEBOF_03860 1.6e-264 flgK N flagellar hook-associated protein
NMFLEBOF_03861 4.1e-78 flgN NOU FlgN protein
NMFLEBOF_03862 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
NMFLEBOF_03863 4.6e-73 yvyF S flagellar protein
NMFLEBOF_03864 1.2e-126 comFC S Phosphoribosyl transferase domain
NMFLEBOF_03865 5.7e-46 comFB S Late competence development protein ComFB
NMFLEBOF_03866 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
NMFLEBOF_03867 2.1e-154 degV S protein conserved in bacteria
NMFLEBOF_03868 5.8e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
NMFLEBOF_03869 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
NMFLEBOF_03870 4.9e-106 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
NMFLEBOF_03871 1.3e-113 yvhJ K Transcriptional regulator
NMFLEBOF_03875 4.5e-42 S Psort location CytoplasmicMembrane, score
NMFLEBOF_03877 1e-28 S CytoplasmicMembrane, score 9.99
NMFLEBOF_03878 6.7e-79 V ABC transporter, ATP-binding protein
NMFLEBOF_03879 1e-13
NMFLEBOF_03880 3.4e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
NMFLEBOF_03881 3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
NMFLEBOF_03882 4.4e-135 tuaG GT2 M Glycosyltransferase like family 2
NMFLEBOF_03883 2.7e-107 tuaF M protein involved in exopolysaccharide biosynthesis
NMFLEBOF_03884 3.2e-243 tuaE M Teichuronic acid biosynthesis protein
NMFLEBOF_03886 3.2e-237 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMFLEBOF_03887 4.2e-201 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
NMFLEBOF_03888 1.3e-231 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
NMFLEBOF_03889 4.7e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
NMFLEBOF_03890 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03892 8.5e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NMFLEBOF_03893 2.1e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NMFLEBOF_03894 6.1e-10 L COG2963 Transposase and inactivated derivatives
NMFLEBOF_03895 6.3e-160 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
NMFLEBOF_03896 4.1e-134 tagG GM Transport permease protein
NMFLEBOF_03898 4.1e-281 tagF2 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NMFLEBOF_03899 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMFLEBOF_03900 4.9e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
NMFLEBOF_03901 6.6e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NMFLEBOF_03902 4.6e-192 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
NMFLEBOF_03903 2.8e-213 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NMFLEBOF_03904 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
NMFLEBOF_03905 1.1e-196 gerBA EG Spore germination protein
NMFLEBOF_03906 1.8e-49 gerBB E Spore germination protein
NMFLEBOF_03907 1.6e-202 gerAC S Spore germination protein
NMFLEBOF_03908 7.2e-204 ywtG EGP Major facilitator Superfamily
NMFLEBOF_03909 3.5e-140 ywtF K Transcriptional regulator
NMFLEBOF_03910 5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
NMFLEBOF_03911 2.9e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
NMFLEBOF_03913 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03914 3.6e-21 ywtC
NMFLEBOF_03915 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
NMFLEBOF_03916 8.6e-70 pgsC S biosynthesis protein
NMFLEBOF_03917 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
NMFLEBOF_03918 1.9e-198 L COG3385 FOG Transposase and inactivated derivatives
NMFLEBOF_03919 3e-176 rbsR K transcriptional
NMFLEBOF_03920 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NMFLEBOF_03921 2.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
NMFLEBOF_03922 2.8e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
NMFLEBOF_03923 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
NMFLEBOF_03924 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
NMFLEBOF_03925 1.2e-91 batE T Sh3 type 3 domain protein
NMFLEBOF_03926 8e-48 ywsA S Protein of unknown function (DUF3892)
NMFLEBOF_03927 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
NMFLEBOF_03928 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
NMFLEBOF_03929 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
NMFLEBOF_03930 1.1e-169 alsR K LysR substrate binding domain
NMFLEBOF_03931 1.1e-206 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NMFLEBOF_03932 1.4e-124 ywrJ
NMFLEBOF_03933 1.1e-22 cotB
NMFLEBOF_03934 1.1e-206 cotH M Spore Coat
NMFLEBOF_03935 1.3e-12
NMFLEBOF_03936 1.5e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NMFLEBOF_03937 5e-54 S Domain of unknown function (DUF4181)
NMFLEBOF_03938 9.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
NMFLEBOF_03939 8e-82 ywrC K Transcriptional regulator
NMFLEBOF_03940 1.6e-103 ywrB P Chromate transporter
NMFLEBOF_03941 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
NMFLEBOF_03942 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_03944 4.8e-99 ywqN S NAD(P)H-dependent
NMFLEBOF_03945 1.4e-161 K Transcriptional regulator
NMFLEBOF_03946 4.9e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
NMFLEBOF_03947 3.9e-25
NMFLEBOF_03948 3.3e-29 S protein secretion by the type VII secretion system
NMFLEBOF_03949 1.7e-78 ywqJ S Pre-toxin TG
NMFLEBOF_03950 5.2e-17
NMFLEBOF_03951 6.1e-43
NMFLEBOF_03952 2e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
NMFLEBOF_03953 3.9e-38 ywqI S Family of unknown function (DUF5344)
NMFLEBOF_03954 9.7e-23 S Domain of unknown function (DUF5082)
NMFLEBOF_03955 5.1e-150 ywqG S Domain of unknown function (DUF1963)
NMFLEBOF_03956 1.1e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
NMFLEBOF_03957 6.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
NMFLEBOF_03958 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
NMFLEBOF_03959 2e-116 ywqC M biosynthesis protein
NMFLEBOF_03960 1.2e-17
NMFLEBOF_03961 8.6e-306 ywqB S SWIM zinc finger
NMFLEBOF_03962 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
NMFLEBOF_03963 5.7e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
NMFLEBOF_03964 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
NMFLEBOF_03965 2.2e-57 ssbB L Single-stranded DNA-binding protein
NMFLEBOF_03966 1.2e-29 ywpG
NMFLEBOF_03967 6.9e-66 ywpF S YwpF-like protein
NMFLEBOF_03968 5.2e-50 srtA 3.4.22.70 M Sortase family
NMFLEBOF_03969 2.1e-144 ywpD T Histidine kinase
NMFLEBOF_03970 1.1e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NMFLEBOF_03971 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
NMFLEBOF_03972 7.5e-197 S aspartate phosphatase
NMFLEBOF_03973 2.6e-141 flhP N flagellar basal body
NMFLEBOF_03974 3.2e-123 flhO N flagellar basal body
NMFLEBOF_03975 3.5e-180 mbl D Rod shape-determining protein
NMFLEBOF_03976 3e-44 spoIIID K Stage III sporulation protein D
NMFLEBOF_03977 2.1e-70 ywoH K COG1846 Transcriptional regulators
NMFLEBOF_03978 2.7e-211 ywoG EGP Major facilitator Superfamily
NMFLEBOF_03979 9.8e-229 ywoF P Right handed beta helix region
NMFLEBOF_03980 4.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
NMFLEBOF_03981 4.1e-240 ywoD EGP Major facilitator superfamily
NMFLEBOF_03982 6.8e-104 phzA Q Isochorismatase family
NMFLEBOF_03983 1.7e-76
NMFLEBOF_03984 1.3e-224 amt P Ammonium transporter
NMFLEBOF_03985 1.6e-58 nrgB K Belongs to the P(II) protein family
NMFLEBOF_03986 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
NMFLEBOF_03987 5.6e-71 ywnJ S VanZ like family
NMFLEBOF_03988 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
NMFLEBOF_03989 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
NMFLEBOF_03990 1.3e-08 ywnC S Family of unknown function (DUF5362)
NMFLEBOF_03991 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
NMFLEBOF_03992 2.2e-70 ywnF S Family of unknown function (DUF5392)
NMFLEBOF_03993 7.8e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NMFLEBOF_03994 2.1e-140 mta K transcriptional
NMFLEBOF_03995 2.6e-59 ywnC S Family of unknown function (DUF5362)
NMFLEBOF_03996 2.3e-87 ywnB S NAD(P)H-binding
NMFLEBOF_03997 5.9e-14 ywnB S NAD(P)H-binding
NMFLEBOF_03998 1.7e-64 ywnA K Transcriptional regulator
NMFLEBOF_03999 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
NMFLEBOF_04000 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
NMFLEBOF_04001 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
NMFLEBOF_04003 1.4e-10 csbD K CsbD-like
NMFLEBOF_04004 3e-84 ywmF S Peptidase M50
NMFLEBOF_04005 7.9e-104 S response regulator aspartate phosphatase
NMFLEBOF_04006 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NMFLEBOF_04007 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NMFLEBOF_04009 1.4e-119 ywmD S protein containing a von Willebrand factor type A (vWA) domain
NMFLEBOF_04010 9.6e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
NMFLEBOF_04011 7.5e-178 spoIID D Stage II sporulation protein D
NMFLEBOF_04012 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMFLEBOF_04013 9e-133 ywmB S TATA-box binding
NMFLEBOF_04014 1.3e-32 ywzB S membrane
NMFLEBOF_04015 1.4e-86 ywmA
NMFLEBOF_04016 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NMFLEBOF_04017 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NMFLEBOF_04018 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NMFLEBOF_04019 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NMFLEBOF_04020 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMFLEBOF_04021 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NMFLEBOF_04022 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NMFLEBOF_04023 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
NMFLEBOF_04024 2.5e-62 atpI S ATP synthase
NMFLEBOF_04025 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NMFLEBOF_04026 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NMFLEBOF_04027 7.2e-95 ywlG S Belongs to the UPF0340 family
NMFLEBOF_04028 8.3e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
NMFLEBOF_04029 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NMFLEBOF_04030 4.9e-91 mntP P Probably functions as a manganese efflux pump
NMFLEBOF_04031 1.3e-193 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NMFLEBOF_04032 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
NMFLEBOF_04033 6.1e-112 spoIIR S stage II sporulation protein R
NMFLEBOF_04034 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
NMFLEBOF_04036 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NMFLEBOF_04037 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NMFLEBOF_04038 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_04039 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
NMFLEBOF_04040 8.6e-160 ywkB S Membrane transport protein
NMFLEBOF_04041 0.0 sfcA 1.1.1.38 C malic enzyme
NMFLEBOF_04042 7e-104 tdk 2.7.1.21 F thymidine kinase
NMFLEBOF_04043 1.1e-32 rpmE J Binds the 23S rRNA
NMFLEBOF_04044 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
NMFLEBOF_04045 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
NMFLEBOF_04046 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NMFLEBOF_04048 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NMFLEBOF_04049 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
NMFLEBOF_04050 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
NMFLEBOF_04051 1.8e-90 ywjG S Domain of unknown function (DUF2529)
NMFLEBOF_04052 1.5e-134 L Integrase core domain
NMFLEBOF_04053 6e-44 tnpIS3 L Transposase
NMFLEBOF_04054 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NMFLEBOF_04055 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NMFLEBOF_04056 7e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
NMFLEBOF_04057 0.0 fadF C COG0247 Fe-S oxidoreductase
NMFLEBOF_04058 1.1e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
NMFLEBOF_04059 2.1e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
NMFLEBOF_04060 7.1e-09 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04061 3.1e-86 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04062 2.5e-85 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04064 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NMFLEBOF_04065 2.3e-72 ywiB S protein conserved in bacteria
NMFLEBOF_04066 1e-07 S Bacteriocin subtilosin A
NMFLEBOF_04067 6.4e-270 C Fe-S oxidoreductases
NMFLEBOF_04069 8.2e-131 cbiO V ABC transporter
NMFLEBOF_04070 9.7e-231 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
NMFLEBOF_04071 5.7e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
NMFLEBOF_04072 1.1e-247 L Peptidase, M16
NMFLEBOF_04074 1.1e-235 ywhL CO amine dehydrogenase activity
NMFLEBOF_04075 4.6e-77 ywhK CO amine dehydrogenase activity
NMFLEBOF_04076 1.5e-99 ywhK CO amine dehydrogenase activity
NMFLEBOF_04077 5.8e-78 S aspartate phosphatase
NMFLEBOF_04079 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
NMFLEBOF_04080 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
NMFLEBOF_04081 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
NMFLEBOF_04082 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NMFLEBOF_04083 3.6e-49
NMFLEBOF_04084 5.2e-95 ywhD S YwhD family
NMFLEBOF_04085 5.1e-119 ywhC S Peptidase family M50
NMFLEBOF_04086 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
NMFLEBOF_04087 9.5e-71 ywhA K Transcriptional regulator
NMFLEBOF_04088 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NMFLEBOF_04090 7.7e-242 mmr U Major Facilitator Superfamily
NMFLEBOF_04091 2.8e-79 yffB K Transcriptional regulator
NMFLEBOF_04092 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
NMFLEBOF_04093 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
NMFLEBOF_04094 3.1e-36 ywzC S Belongs to the UPF0741 family
NMFLEBOF_04095 1e-110 rsfA_1
NMFLEBOF_04096 9.1e-156 ywfM EG EamA-like transporter family
NMFLEBOF_04097 2.1e-154 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
NMFLEBOF_04098 1.1e-156 cysL K Transcriptional regulator
NMFLEBOF_04099 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
NMFLEBOF_04100 3.3e-146 ywfI C May function as heme-dependent peroxidase
NMFLEBOF_04101 3.7e-137 IQ Enoyl-(Acyl carrier protein) reductase
NMFLEBOF_04102 1.8e-231 ywfG 2.6.1.83 E Aminotransferase class I and II
NMFLEBOF_04103 1.9e-209 bacE EGP Major facilitator Superfamily
NMFLEBOF_04104 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
NMFLEBOF_04105 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_04106 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
NMFLEBOF_04107 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
NMFLEBOF_04108 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04110 7.8e-206 ywfA EGP Major facilitator Superfamily
NMFLEBOF_04111 5.7e-261 lysP E amino acid
NMFLEBOF_04112 0.0 rocB E arginine degradation protein
NMFLEBOF_04113 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
NMFLEBOF_04114 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
NMFLEBOF_04115 1.2e-77
NMFLEBOF_04116 5.1e-86 spsL 5.1.3.13 M Spore Coat
NMFLEBOF_04117 1e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
NMFLEBOF_04118 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
NMFLEBOF_04119 2.1e-137 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
NMFLEBOF_04120 2e-186 spsG M Spore Coat
NMFLEBOF_04121 2.9e-128 spsF M Spore Coat
NMFLEBOF_04122 2.1e-213 spsE 2.5.1.56 M acid synthase
NMFLEBOF_04123 4.9e-162 spsD 2.3.1.210 K Spore Coat
NMFLEBOF_04124 3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
NMFLEBOF_04125 4.5e-263 spsB M Capsule polysaccharide biosynthesis protein
NMFLEBOF_04126 1.8e-144 spsA M Spore Coat
NMFLEBOF_04128 1.4e-71 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
NMFLEBOF_04129 4.3e-59 ywdK S small membrane protein
NMFLEBOF_04130 3.7e-238 ywdJ F Xanthine uracil
NMFLEBOF_04131 4.2e-47 ywdI S Family of unknown function (DUF5327)
NMFLEBOF_04132 1.4e-256 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMFLEBOF_04133 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NMFLEBOF_04134 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
NMFLEBOF_04135 3e-145 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NMFLEBOF_04136 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04138 2e-28 ywdA
NMFLEBOF_04139 1.4e-286 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
NMFLEBOF_04140 1.6e-244 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_04141 5.7e-138 focA P Formate/nitrite transporter
NMFLEBOF_04142 1.2e-149 sacT K transcriptional antiterminator
NMFLEBOF_04144 0.0 vpr O Belongs to the peptidase S8 family
NMFLEBOF_04145 2.2e-182 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMFLEBOF_04146 1.4e-136 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
NMFLEBOF_04147 1.5e-137 rodA D Belongs to the SEDS family
NMFLEBOF_04149 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
NMFLEBOF_04150 2.2e-63 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMFLEBOF_04151 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
NMFLEBOF_04152 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NMFLEBOF_04153 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
NMFLEBOF_04154 1e-35 ywzA S membrane
NMFLEBOF_04155 8.6e-303 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NMFLEBOF_04156 1.5e-227 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NMFLEBOF_04157 9.5e-60 gtcA S GtrA-like protein
NMFLEBOF_04158 5.5e-121 ywcC K transcriptional regulator
NMFLEBOF_04160 6.4e-48 ywcB S Protein of unknown function, DUF485
NMFLEBOF_04161 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NMFLEBOF_04162 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04163 6.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
NMFLEBOF_04164 1.9e-223 ywbN P Dyp-type peroxidase family protein
NMFLEBOF_04165 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
NMFLEBOF_04166 3.1e-246 P COG0672 High-affinity Fe2 Pb2 permease
NMFLEBOF_04167 2.9e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
NMFLEBOF_04168 2.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NMFLEBOF_04169 8.1e-152 ywbI K Transcriptional regulator
NMFLEBOF_04170 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
NMFLEBOF_04171 2.3e-111 ywbG M effector of murein hydrolase
NMFLEBOF_04172 7.6e-206 ywbF EGP Major facilitator Superfamily
NMFLEBOF_04173 1.2e-26 ywbE S Uncharacterized conserved protein (DUF2196)
NMFLEBOF_04174 1.9e-217 ywbD 2.1.1.191 J Methyltransferase
NMFLEBOF_04175 9.9e-67 ywbC 4.4.1.5 E glyoxalase
NMFLEBOF_04176 2e-126 ywbB S Protein of unknown function (DUF2711)
NMFLEBOF_04177 6.2e-157 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFLEBOF_04178 2.4e-67 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFLEBOF_04179 1.4e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
NMFLEBOF_04180 1.6e-236 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
NMFLEBOF_04181 1.2e-152 sacY K transcriptional antiterminator
NMFLEBOF_04182 3.5e-168 gspA M General stress
NMFLEBOF_04183 7.4e-124 ywaF S Integral membrane protein
NMFLEBOF_04184 2.3e-87 ywaE K Transcriptional regulator
NMFLEBOF_04185 6.4e-232 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NMFLEBOF_04186 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
NMFLEBOF_04187 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
NMFLEBOF_04188 6e-44 tnpIS3 L Transposase
NMFLEBOF_04189 1.5e-134 L Integrase core domain
NMFLEBOF_04190 3.5e-166 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
NMFLEBOF_04191 4.8e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_04192 1.2e-232 dltB M membrane protein involved in D-alanine export
NMFLEBOF_04193 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NMFLEBOF_04194 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NMFLEBOF_04195 8.6e-47 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_04197 4.9e-34 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_04198 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
NMFLEBOF_04199 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
NMFLEBOF_04200 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
NMFLEBOF_04201 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NMFLEBOF_04202 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
NMFLEBOF_04203 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
NMFLEBOF_04204 9.3e-19 yxzF
NMFLEBOF_04205 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NMFLEBOF_04206 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
NMFLEBOF_04207 2.6e-214 yxlH EGP Major facilitator Superfamily
NMFLEBOF_04208 3e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
NMFLEBOF_04209 6.3e-165 yxlF V ABC transporter, ATP-binding protein
NMFLEBOF_04210 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
NMFLEBOF_04211 2.2e-28
NMFLEBOF_04212 5.6e-47 yxlC S Family of unknown function (DUF5345)
NMFLEBOF_04213 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
NMFLEBOF_04214 5e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
NMFLEBOF_04215 1.4e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NMFLEBOF_04216 0.0 cydD V ATP-binding protein
NMFLEBOF_04217 1e-309 cydD V ATP-binding
NMFLEBOF_04218 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
NMFLEBOF_04219 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
NMFLEBOF_04220 4.7e-228 cimH C COG3493 Na citrate symporter
NMFLEBOF_04221 4.7e-311 3.4.24.84 O Peptidase family M48
NMFLEBOF_04223 2.8e-154 yxkH G Polysaccharide deacetylase
NMFLEBOF_04224 5.9e-205 msmK P Belongs to the ABC transporter superfamily
NMFLEBOF_04225 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
NMFLEBOF_04226 3.7e-271 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMFLEBOF_04227 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NMFLEBOF_04229 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04230 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NMFLEBOF_04231 7.7e-77 S Protein of unknown function (DUF1453)
NMFLEBOF_04232 1.4e-119 yxjM T Signal transduction histidine kinase
NMFLEBOF_04233 1.2e-58 yxjM T Signal transduction histidine kinase
NMFLEBOF_04234 9.8e-115 K helix_turn_helix, Lux Regulon
NMFLEBOF_04235 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NMFLEBOF_04237 1.6e-85 yxjI S LURP-one-related
NMFLEBOF_04238 5.1e-220 yxjG 2.1.1.14 E Methionine synthase
NMFLEBOF_04239 1.7e-218 yxjG 2.1.1.14 E Methionine synthase
NMFLEBOF_04240 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
NMFLEBOF_04241 8.8e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
NMFLEBOF_04242 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
NMFLEBOF_04243 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
NMFLEBOF_04244 7.4e-155 rlmA 2.1.1.187 Q Methyltransferase domain
NMFLEBOF_04245 1.3e-210 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMFLEBOF_04246 8.8e-71 T Domain of unknown function (DUF4163)
NMFLEBOF_04247 3e-47 yxiS
NMFLEBOF_04248 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
NMFLEBOF_04249 6.6e-224 citH C Citrate transporter
NMFLEBOF_04250 3.6e-142 exoK GH16 M licheninase activity
NMFLEBOF_04251 8.3e-151 licT K transcriptional antiterminator
NMFLEBOF_04252 6.8e-111
NMFLEBOF_04253 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
NMFLEBOF_04254 2.5e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
NMFLEBOF_04255 8.6e-215 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
NMFLEBOF_04258 3.5e-43 yxiJ S YxiJ-like protein
NMFLEBOF_04261 3.2e-32
NMFLEBOF_04262 1e-38 yxiI S Protein of unknown function (DUF2716)
NMFLEBOF_04263 1e-135
NMFLEBOF_04264 8.3e-13 yxiG
NMFLEBOF_04265 7.6e-16 yxiG
NMFLEBOF_04266 1.9e-38 S Protein of unknown function (DUF2750)
NMFLEBOF_04267 3.4e-52 yxxG
NMFLEBOF_04268 4.3e-68 yxiG
NMFLEBOF_04269 4.1e-44
NMFLEBOF_04270 4.9e-76
NMFLEBOF_04271 4e-93 S Protein of unknown function (DUF4240)
NMFLEBOF_04272 7.2e-139
NMFLEBOF_04274 7e-55
NMFLEBOF_04275 6.1e-80 wapA M COG3209 Rhs family protein
NMFLEBOF_04276 4.1e-14 yxiJ S YxiJ-like protein
NMFLEBOF_04277 0.0 wapA M COG3209 Rhs family protein
NMFLEBOF_04278 1.8e-162 yxxF EG EamA-like transporter family
NMFLEBOF_04279 1.2e-124 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
NMFLEBOF_04280 2.1e-121 1.14.11.45 E 2OG-Fe dioxygenase
NMFLEBOF_04281 1.1e-72 yxiE T Belongs to the universal stress protein A family
NMFLEBOF_04282 5.7e-252 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMFLEBOF_04283 2.9e-40
NMFLEBOF_04284 1.1e-77 S SMI1 / KNR4 family
NMFLEBOF_04285 1.6e-58 S nuclease activity
NMFLEBOF_04286 1.9e-198 L COG3385 FOG Transposase and inactivated derivatives
NMFLEBOF_04287 6.1e-239 S nuclease activity
NMFLEBOF_04288 1.4e-38 yxiC S Family of unknown function (DUF5344)
NMFLEBOF_04289 4.6e-21 S Domain of unknown function (DUF5082)
NMFLEBOF_04290 0.0 L HKD family nuclease
NMFLEBOF_04291 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
NMFLEBOF_04292 3.6e-166 L Protein of unknown function (DUF2726)
NMFLEBOF_04293 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04295 1.8e-242 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
NMFLEBOF_04296 2.3e-257 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NMFLEBOF_04297 1.5e-161 lysP E amino acid
NMFLEBOF_04298 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
NMFLEBOF_04299 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NMFLEBOF_04300 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NMFLEBOF_04301 3.9e-173 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
NMFLEBOF_04302 1.4e-150 yxxB S Domain of Unknown Function (DUF1206)
NMFLEBOF_04303 8.1e-194 eutH E Ethanolamine utilisation protein, EutH
NMFLEBOF_04304 3e-251 yxeQ S MmgE/PrpD family
NMFLEBOF_04305 4e-212 yxeP 3.5.1.47 E hydrolase activity
NMFLEBOF_04306 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
NMFLEBOF_04307 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
NMFLEBOF_04308 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
NMFLEBOF_04309 2.6e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NMFLEBOF_04310 1.6e-252 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NMFLEBOF_04311 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
NMFLEBOF_04312 2.3e-150 yidA S hydrolases of the HAD superfamily
NMFLEBOF_04315 4.3e-19 yxeE
NMFLEBOF_04316 5.6e-16 yxeD
NMFLEBOF_04318 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04319 1.4e-68
NMFLEBOF_04320 1.8e-167 fhuD P ABC transporter
NMFLEBOF_04321 1.5e-58 yxeA S Protein of unknown function (DUF1093)
NMFLEBOF_04322 0.0 yxdM V ABC transporter (permease)
NMFLEBOF_04323 3.7e-137 yxdL V ABC transporter, ATP-binding protein
NMFLEBOF_04324 4.2e-178 T PhoQ Sensor
NMFLEBOF_04325 4.6e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_04326 3e-159 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
NMFLEBOF_04327 3.3e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
NMFLEBOF_04328 8.6e-167 iolH G Xylose isomerase-like TIM barrel
NMFLEBOF_04329 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
NMFLEBOF_04330 4e-232 iolF EGP Major facilitator Superfamily
NMFLEBOF_04331 1.8e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
NMFLEBOF_04332 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
NMFLEBOF_04333 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
NMFLEBOF_04334 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
NMFLEBOF_04335 3.3e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
NMFLEBOF_04336 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
NMFLEBOF_04337 4.1e-175 iolS C Aldo keto reductase
NMFLEBOF_04338 1.1e-41
NMFLEBOF_04340 1.3e-12 S CGNR zinc finger
NMFLEBOF_04341 2.2e-77 T HPP family
NMFLEBOF_04342 8.3e-31 csbC EGP Major facilitator Superfamily
NMFLEBOF_04343 1.2e-183 csbC EGP Major facilitator Superfamily
NMFLEBOF_04344 8.7e-11 csbC EGP Major facilitator Superfamily
NMFLEBOF_04345 8.3e-201 L COG3666 Transposase and inactivated derivatives
NMFLEBOF_04346 0.0 htpG O Molecular chaperone. Has ATPase activity
NMFLEBOF_04348 1.7e-17 IQ Enoyl-(Acyl carrier protein) reductase
NMFLEBOF_04349 3e-122 IQ Enoyl-(Acyl carrier protein) reductase
NMFLEBOF_04350 1.1e-206 yxbF K Bacterial regulatory proteins, tetR family
NMFLEBOF_04351 7.6e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
NMFLEBOF_04352 8.8e-33 yxaI S membrane protein domain
NMFLEBOF_04353 5.7e-63 S Family of unknown function (DUF5391)
NMFLEBOF_04354 1.5e-74 yxaI S membrane protein domain
NMFLEBOF_04355 1.4e-223 P Protein of unknown function (DUF418)
NMFLEBOF_04356 1.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
NMFLEBOF_04357 4.6e-100 yxaF K Transcriptional regulator
NMFLEBOF_04358 2.8e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
NMFLEBOF_04359 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
NMFLEBOF_04360 5.2e-50 S LrgA family
NMFLEBOF_04361 2.6e-118 yxaC M effector of murein hydrolase
NMFLEBOF_04362 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
NMFLEBOF_04363 1.1e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NMFLEBOF_04364 1.2e-126 gntR K transcriptional
NMFLEBOF_04365 3.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
NMFLEBOF_04366 3.8e-230 gntP EG COG2610 H gluconate symporter and related permeases
NMFLEBOF_04367 1e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NMFLEBOF_04368 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
NMFLEBOF_04369 3.6e-285 ahpF O Alkyl hydroperoxide reductase
NMFLEBOF_04370 7e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NMFLEBOF_04371 5.9e-11 bglF G phosphotransferase system
NMFLEBOF_04372 1.9e-124 yydK K Transcriptional regulator
NMFLEBOF_04373 1.6e-118 S ABC-2 family transporter protein
NMFLEBOF_04374 1.6e-109 prrC P ABC transporter
NMFLEBOF_04375 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
NMFLEBOF_04376 1.7e-37 L COG3385 FOG Transposase and inactivated derivatives
NMFLEBOF_04377 3.2e-77 O Hsp20/alpha crystallin family
NMFLEBOF_04378 8.9e-12 cwlJ 3.5.1.28 M Cell wall
NMFLEBOF_04379 9.9e-119 L PhoH-like protein
NMFLEBOF_04380 1.1e-220 L Transposase
NMFLEBOF_04381 3.2e-37
NMFLEBOF_04382 3.6e-274 V Abi-like protein
NMFLEBOF_04383 9.9e-293 L Superfamily I DNA and RNA helicases
NMFLEBOF_04384 0.0 L AAA ATPase domain
NMFLEBOF_04385 6.6e-116 S HTH-like domain
NMFLEBOF_04386 3.3e-43 S transposition, DNA-mediated
NMFLEBOF_04387 2.4e-11
NMFLEBOF_04388 2.5e-43
NMFLEBOF_04389 2e-137 L COG2801 Transposase and inactivated derivatives
NMFLEBOF_04390 9.1e-50 L Transposase
NMFLEBOF_04391 5.7e-120 L helicase superfamily c-terminal domain
NMFLEBOF_04393 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NMFLEBOF_04394 4.2e-09 S YyzF-like protein
NMFLEBOF_04395 1.3e-67
NMFLEBOF_04396 1.1e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
NMFLEBOF_04398 1.7e-30 yycQ S Protein of unknown function (DUF2651)
NMFLEBOF_04399 7.2e-164 yycP
NMFLEBOF_04400 1.4e-18 yycP
NMFLEBOF_04401 9.3e-122 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
NMFLEBOF_04402 7.1e-83 yycN 2.3.1.128 K Acetyltransferase
NMFLEBOF_04403 5.2e-15 S aspartate phosphatase
NMFLEBOF_04404 1.8e-157 S aspartate phosphatase
NMFLEBOF_04406 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
NMFLEBOF_04407 1.3e-260 rocE E amino acid
NMFLEBOF_04408 4.4e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
NMFLEBOF_04409 7.4e-16
NMFLEBOF_04410 2.8e-94
NMFLEBOF_04411 2.3e-24 S Sporulation delaying protein SdpA
NMFLEBOF_04412 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
NMFLEBOF_04413 1.2e-40 sdpR K transcriptional
NMFLEBOF_04414 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
NMFLEBOF_04415 2.7e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NMFLEBOF_04416 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
NMFLEBOF_04417 1.2e-154 yycI S protein conserved in bacteria
NMFLEBOF_04418 6.4e-257 yycH S protein conserved in bacteria
NMFLEBOF_04419 0.0 vicK 2.7.13.3 T Histidine kinase
NMFLEBOF_04420 1.5e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
NMFLEBOF_04425 3.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NMFLEBOF_04426 1.9e-74 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_04427 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NMFLEBOF_04428 5.6e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
NMFLEBOF_04430 1.9e-15 yycC K YycC-like protein
NMFLEBOF_04431 7.9e-219 yeaN P COG2807 Cyanate permease
NMFLEBOF_04432 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NMFLEBOF_04433 2.2e-73 rplI J binds to the 23S rRNA
NMFLEBOF_04434 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NMFLEBOF_04435 2e-27 yybS S membrane
NMFLEBOF_04436 3.9e-94 yybS S membrane
NMFLEBOF_04438 4e-14 cotF M Spore coat protein
NMFLEBOF_04439 1.7e-51 cotF M Spore coat protein
NMFLEBOF_04440 1.7e-66 ydeP3 K Transcriptional regulator
NMFLEBOF_04441 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
NMFLEBOF_04442 1.1e-61
NMFLEBOF_04444 4.7e-56 yybO G COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_04445 1.6e-157 yybO G COG0477 Permeases of the major facilitator superfamily
NMFLEBOF_04446 4.8e-110 K TipAS antibiotic-recognition domain
NMFLEBOF_04447 4.8e-124
NMFLEBOF_04448 8.6e-66 yybH S SnoaL-like domain
NMFLEBOF_04449 1.4e-118 yybG S Pentapeptide repeat-containing protein
NMFLEBOF_04450 6.7e-105 ynfM EGP Major facilitator Superfamily
NMFLEBOF_04451 1.1e-80 S Metallo-beta-lactamase superfamily
NMFLEBOF_04452 5.6e-77 yybA 2.3.1.57 K transcriptional
NMFLEBOF_04453 4.2e-69 yjcF S Acetyltransferase (GNAT) domain
NMFLEBOF_04454 6.5e-97 yyaS S Membrane
NMFLEBOF_04455 1.5e-66 yyaR K Acetyltransferase (GNAT) domain
NMFLEBOF_04456 4.1e-36 yyaQ S YjbR
NMFLEBOF_04457 2.6e-103 yyaP 1.5.1.3 H RibD C-terminal domain
NMFLEBOF_04458 2e-82 yosT L Bacterial transcription activator, effector binding domain
NMFLEBOF_04459 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
NMFLEBOF_04460 2.3e-167 yyaK S CAAX protease self-immunity
NMFLEBOF_04461 1.8e-243 EGP Major facilitator superfamily
NMFLEBOF_04462 1.7e-91 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
NMFLEBOF_04463 1.9e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
NMFLEBOF_04464 1.4e-121 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NMFLEBOF_04465 3.9e-47 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
NMFLEBOF_04466 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
NMFLEBOF_04467 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NMFLEBOF_04468 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NMFLEBOF_04469 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
NMFLEBOF_04470 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NMFLEBOF_04471 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
NMFLEBOF_04472 2.3e-33 yyzM S protein conserved in bacteria
NMFLEBOF_04473 8.1e-177 yyaD S Membrane
NMFLEBOF_04474 1.6e-111 yyaC S Sporulation protein YyaC
NMFLEBOF_04475 3.2e-45 L transposase activity
NMFLEBOF_04476 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
NMFLEBOF_04477 2.1e-149 spo0J K Belongs to the ParB family
NMFLEBOF_04478 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
NMFLEBOF_04479 3.7e-73 S Bacterial PH domain
NMFLEBOF_04480 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
NMFLEBOF_04481 9.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
NMFLEBOF_04482 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NMFLEBOF_04483 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NMFLEBOF_04484 5.5e-107 jag S single-stranded nucleic acid binding R3H
NMFLEBOF_04485 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NMFLEBOF_04486 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)