ORF_ID e_value Gene_name EC_number CAZy COGs Description
KFDAFNOG_00001 1.6e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFDAFNOG_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KFDAFNOG_00003 2.4e-33 yaaA S S4 domain
KFDAFNOG_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFDAFNOG_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
KFDAFNOG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFDAFNOG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFDAFNOG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00011 1e-181 yaaC S YaaC-like Protein
KFDAFNOG_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KFDAFNOG_00013 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KFDAFNOG_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KFDAFNOG_00015 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KFDAFNOG_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFDAFNOG_00017 1.3e-09
KFDAFNOG_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KFDAFNOG_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KFDAFNOG_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
KFDAFNOG_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
KFDAFNOG_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KFDAFNOG_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFDAFNOG_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFDAFNOG_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFDAFNOG_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KFDAFNOG_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
KFDAFNOG_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
KFDAFNOG_00032 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KFDAFNOG_00033 1.2e-200 yaaN P Belongs to the TelA family
KFDAFNOG_00034 8.7e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KFDAFNOG_00035 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFDAFNOG_00036 2.2e-54 yaaQ S protein conserved in bacteria
KFDAFNOG_00037 1.5e-71 yaaR S protein conserved in bacteria
KFDAFNOG_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
KFDAFNOG_00039 6.1e-146 yaaT S stage 0 sporulation protein
KFDAFNOG_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
KFDAFNOG_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KFDAFNOG_00042 2.8e-48 yazA L endonuclease containing a URI domain
KFDAFNOG_00043 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFDAFNOG_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KFDAFNOG_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFDAFNOG_00046 1.2e-143 tatD L hydrolase, TatD
KFDAFNOG_00047 2e-167 rpfB GH23 T protein conserved in bacteria
KFDAFNOG_00048 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KFDAFNOG_00049 6.9e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KFDAFNOG_00050 1.6e-136 yabG S peptidase
KFDAFNOG_00051 7.8e-39 veg S protein conserved in bacteria
KFDAFNOG_00052 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFDAFNOG_00053 1e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KFDAFNOG_00054 5.6e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KFDAFNOG_00055 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KFDAFNOG_00056 2.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFDAFNOG_00057 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFDAFNOG_00058 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFDAFNOG_00059 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KFDAFNOG_00060 2.4e-39 yabK S Peptide ABC transporter permease
KFDAFNOG_00061 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFDAFNOG_00062 1.5e-92 spoVT K stage V sporulation protein
KFDAFNOG_00063 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_00064 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KFDAFNOG_00065 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KFDAFNOG_00066 1.5e-49 yabP S Sporulation protein YabP
KFDAFNOG_00067 2.5e-107 yabQ S spore cortex biosynthesis protein
KFDAFNOG_00068 1.1e-44 divIC D Septum formation initiator
KFDAFNOG_00069 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KFDAFNOG_00072 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KFDAFNOG_00073 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KFDAFNOG_00074 1.4e-184 KLT serine threonine protein kinase
KFDAFNOG_00075 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KFDAFNOG_00076 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KFDAFNOG_00077 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFDAFNOG_00078 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFDAFNOG_00079 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFDAFNOG_00080 6.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KFDAFNOG_00081 5.7e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KFDAFNOG_00082 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFDAFNOG_00083 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KFDAFNOG_00084 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KFDAFNOG_00085 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFDAFNOG_00086 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFDAFNOG_00087 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFDAFNOG_00088 4.1e-30 yazB K transcriptional
KFDAFNOG_00089 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFDAFNOG_00090 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KFDAFNOG_00091 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00096 2e-08
KFDAFNOG_00101 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00102 2.9e-76 ctsR K Belongs to the CtsR family
KFDAFNOG_00103 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KFDAFNOG_00104 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KFDAFNOG_00105 0.0 clpC O Belongs to the ClpA ClpB family
KFDAFNOG_00106 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFDAFNOG_00107 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KFDAFNOG_00108 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KFDAFNOG_00109 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KFDAFNOG_00110 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KFDAFNOG_00111 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFDAFNOG_00112 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KFDAFNOG_00113 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFDAFNOG_00114 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KFDAFNOG_00115 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFDAFNOG_00116 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KFDAFNOG_00117 4.4e-115 sigH K Belongs to the sigma-70 factor family
KFDAFNOG_00118 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KFDAFNOG_00119 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KFDAFNOG_00120 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFDAFNOG_00121 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KFDAFNOG_00122 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFDAFNOG_00123 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KFDAFNOG_00124 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
KFDAFNOG_00125 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFDAFNOG_00126 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFDAFNOG_00127 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KFDAFNOG_00128 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFDAFNOG_00129 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KFDAFNOG_00130 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFDAFNOG_00131 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFDAFNOG_00132 2.2e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KFDAFNOG_00133 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KFDAFNOG_00134 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFDAFNOG_00135 3e-105 rplD J Forms part of the polypeptide exit tunnel
KFDAFNOG_00136 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KFDAFNOG_00137 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFDAFNOG_00138 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFDAFNOG_00139 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFDAFNOG_00140 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFDAFNOG_00141 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFDAFNOG_00142 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KFDAFNOG_00143 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFDAFNOG_00144 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFDAFNOG_00145 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFDAFNOG_00146 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFDAFNOG_00147 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFDAFNOG_00148 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFDAFNOG_00149 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFDAFNOG_00150 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFDAFNOG_00151 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFDAFNOG_00152 1.9e-23 rpmD J Ribosomal protein L30
KFDAFNOG_00153 1.8e-72 rplO J binds to the 23S rRNA
KFDAFNOG_00154 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KFDAFNOG_00155 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KFDAFNOG_00156 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KFDAFNOG_00157 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFDAFNOG_00158 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KFDAFNOG_00159 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFDAFNOG_00160 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFDAFNOG_00161 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFDAFNOG_00162 3.6e-58 rplQ J Ribosomal protein L17
KFDAFNOG_00163 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KFDAFNOG_00164 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KFDAFNOG_00165 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KFDAFNOG_00166 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KFDAFNOG_00167 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFDAFNOG_00168 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KFDAFNOG_00169 9e-144 ybaJ Q Methyltransferase domain
KFDAFNOG_00170 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KFDAFNOG_00171 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KFDAFNOG_00172 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KFDAFNOG_00173 1.2e-84 gerD
KFDAFNOG_00174 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KFDAFNOG_00175 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KFDAFNOG_00176 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00179 2e-08
KFDAFNOG_00183 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00185 8.7e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KFDAFNOG_00187 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
KFDAFNOG_00188 4.7e-137 ybbA S Putative esterase
KFDAFNOG_00189 7.4e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00190 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00191 1.4e-165 feuA P Iron-uptake system-binding protein
KFDAFNOG_00192 9.5e-305 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KFDAFNOG_00193 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KFDAFNOG_00194 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KFDAFNOG_00195 1.7e-251 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KFDAFNOG_00196 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_00197 1.4e-150 ybbH K transcriptional
KFDAFNOG_00198 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KFDAFNOG_00199 1.9e-86 ybbJ J acetyltransferase
KFDAFNOG_00200 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KFDAFNOG_00206 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_00207 2.7e-101 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KFDAFNOG_00208 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KFDAFNOG_00209 1.5e-224 ybbR S protein conserved in bacteria
KFDAFNOG_00210 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFDAFNOG_00211 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KFDAFNOG_00212 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFDAFNOG_00213 5.8e-120 adaA 3.2.2.21 K Transcriptional regulator
KFDAFNOG_00214 1.2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFDAFNOG_00215 1.1e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KFDAFNOG_00216 0.0 ybcC S Belongs to the UPF0753 family
KFDAFNOG_00217 1.1e-92 can 4.2.1.1 P carbonic anhydrase
KFDAFNOG_00218 6.2e-45
KFDAFNOG_00219 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
KFDAFNOG_00220 5.1e-50 ybzH K Helix-turn-helix domain
KFDAFNOG_00221 3.8e-202 ybcL EGP Major facilitator Superfamily
KFDAFNOG_00222 1.2e-55
KFDAFNOG_00223 1.5e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KFDAFNOG_00224 3.8e-122 T Transcriptional regulatory protein, C terminal
KFDAFNOG_00225 8.5e-171 T His Kinase A (phospho-acceptor) domain
KFDAFNOG_00226 8.8e-139 KLT Protein tyrosine kinase
KFDAFNOG_00227 2.9e-151 ybdN
KFDAFNOG_00228 1.8e-212 ybdO S Domain of unknown function (DUF4885)
KFDAFNOG_00229 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_00230 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
KFDAFNOG_00231 4.9e-30 ybxH S Family of unknown function (DUF5370)
KFDAFNOG_00232 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
KFDAFNOG_00233 7.1e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KFDAFNOG_00234 4.9e-41 ybyB
KFDAFNOG_00235 1.8e-290 ybeC E amino acid
KFDAFNOG_00236 6.9e-164 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KFDAFNOG_00237 7.3e-258 glpT G -transporter
KFDAFNOG_00238 2.9e-35 S Protein of unknown function (DUF2651)
KFDAFNOG_00239 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
KFDAFNOG_00240 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
KFDAFNOG_00242 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
KFDAFNOG_00243 3.7e-160 ybfH EG EamA-like transporter family
KFDAFNOG_00244 5.2e-145 msmR K AraC-like ligand binding domain
KFDAFNOG_00245 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFDAFNOG_00246 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KFDAFNOG_00248 1e-167 S Alpha/beta hydrolase family
KFDAFNOG_00249 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFDAFNOG_00250 2.7e-85 ybfM S SNARE associated Golgi protein
KFDAFNOG_00251 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KFDAFNOG_00252 2e-45 ybfN
KFDAFNOG_00253 3.3e-191 yceA S Belongs to the UPF0176 family
KFDAFNOG_00254 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KFDAFNOG_00255 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_00256 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KFDAFNOG_00257 4.9e-128 K UTRA
KFDAFNOG_00259 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KFDAFNOG_00260 1.4e-259 mmuP E amino acid
KFDAFNOG_00261 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KFDAFNOG_00262 2.8e-255 agcS E Sodium alanine symporter
KFDAFNOG_00263 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
KFDAFNOG_00264 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
KFDAFNOG_00265 9e-170 glnL T Regulator
KFDAFNOG_00266 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KFDAFNOG_00267 2.9e-271 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KFDAFNOG_00268 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KFDAFNOG_00269 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KFDAFNOG_00270 2.1e-123 ycbG K FCD
KFDAFNOG_00271 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
KFDAFNOG_00272 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
KFDAFNOG_00273 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KFDAFNOG_00274 5.4e-167 eamA1 EG spore germination
KFDAFNOG_00275 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_00276 4.2e-167 T PhoQ Sensor
KFDAFNOG_00277 3.5e-166 ycbN V ABC transporter, ATP-binding protein
KFDAFNOG_00278 1.8e-114 S ABC-2 family transporter protein
KFDAFNOG_00279 8.2e-53 ycbP S Protein of unknown function (DUF2512)
KFDAFNOG_00280 2.8e-78 sleB 3.5.1.28 M Cell wall
KFDAFNOG_00281 3.6e-134 ycbR T vWA found in TerF C terminus
KFDAFNOG_00282 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KFDAFNOG_00283 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KFDAFNOG_00284 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFDAFNOG_00285 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KFDAFNOG_00286 2.9e-199 ycbU E Selenocysteine lyase
KFDAFNOG_00287 3e-225 lmrB EGP the major facilitator superfamily
KFDAFNOG_00288 4.8e-102 yxaF K Transcriptional regulator
KFDAFNOG_00289 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KFDAFNOG_00290 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KFDAFNOG_00291 4.9e-58 S RDD family
KFDAFNOG_00292 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
KFDAFNOG_00293 1.2e-156 2.7.13.3 T GHKL domain
KFDAFNOG_00294 1.2e-126 lytR_2 T LytTr DNA-binding domain
KFDAFNOG_00295 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KFDAFNOG_00296 2.7e-200 natB CP ABC-2 family transporter protein
KFDAFNOG_00297 1.7e-22 yccK C Aldo keto reductase
KFDAFNOG_00298 1e-142 yccK C Aldo keto reductase
KFDAFNOG_00299 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KFDAFNOG_00300 4.2e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_00301 1.5e-259 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_00302 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
KFDAFNOG_00303 6.1e-173 S response regulator aspartate phosphatase
KFDAFNOG_00304 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_00305 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KFDAFNOG_00306 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KFDAFNOG_00307 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KFDAFNOG_00308 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KFDAFNOG_00309 2.7e-188 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_00310 5.1e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KFDAFNOG_00311 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KFDAFNOG_00312 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KFDAFNOG_00313 6.3e-137 terC P Protein of unknown function (DUF475)
KFDAFNOG_00314 0.0 yceG S Putative component of 'biosynthetic module'
KFDAFNOG_00315 2e-192 yceH P Belongs to the TelA family
KFDAFNOG_00316 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
KFDAFNOG_00317 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
KFDAFNOG_00318 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KFDAFNOG_00319 5.1e-229 proV 3.6.3.32 E glycine betaine
KFDAFNOG_00320 1.3e-127 opuAB P glycine betaine
KFDAFNOG_00321 1.5e-163 opuAC E glycine betaine
KFDAFNOG_00322 1.1e-217 amhX S amidohydrolase
KFDAFNOG_00323 8.7e-257 ycgA S Membrane
KFDAFNOG_00324 4.1e-81 ycgB
KFDAFNOG_00325 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KFDAFNOG_00326 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KFDAFNOG_00327 3.3e-289 lctP C L-lactate permease
KFDAFNOG_00328 3.9e-263 mdr EGP Major facilitator Superfamily
KFDAFNOG_00329 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_00330 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KFDAFNOG_00331 1.3e-150 yqcI S YqcI/YcgG family
KFDAFNOG_00332 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_00333 2.4e-112 ycgI S Domain of unknown function (DUF1989)
KFDAFNOG_00334 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KFDAFNOG_00335 2.1e-108 tmrB S AAA domain
KFDAFNOG_00337 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFDAFNOG_00338 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
KFDAFNOG_00339 5.1e-176 oxyR3 K LysR substrate binding domain
KFDAFNOG_00340 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KFDAFNOG_00341 2.9e-145 ycgL S Predicted nucleotidyltransferase
KFDAFNOG_00342 5.1e-170 ycgM E Proline dehydrogenase
KFDAFNOG_00343 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KFDAFNOG_00344 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFDAFNOG_00345 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KFDAFNOG_00346 2.2e-146 ycgQ S membrane
KFDAFNOG_00347 1.2e-139 ycgR S permeases
KFDAFNOG_00348 2.7e-157 I alpha/beta hydrolase fold
KFDAFNOG_00349 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KFDAFNOG_00350 2.7e-282 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KFDAFNOG_00351 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KFDAFNOG_00352 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KFDAFNOG_00353 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFDAFNOG_00354 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KFDAFNOG_00355 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
KFDAFNOG_00356 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KFDAFNOG_00357 5.5e-109 yciB M ErfK YbiS YcfS YnhG
KFDAFNOG_00358 4.6e-227 yciC S GTPases (G3E family)
KFDAFNOG_00359 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KFDAFNOG_00360 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KFDAFNOG_00361 3.6e-47 yckC S membrane
KFDAFNOG_00362 7.8e-52 yckD S Protein of unknown function (DUF2680)
KFDAFNOG_00363 5.7e-39 K MarR family
KFDAFNOG_00364 9.3e-24
KFDAFNOG_00365 6e-121 S AAA domain
KFDAFNOG_00366 7.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KFDAFNOG_00367 6.5e-69 nin S Competence protein J (ComJ)
KFDAFNOG_00368 3e-70 nucA M Deoxyribonuclease NucA/NucB
KFDAFNOG_00369 1.5e-186 tlpC 2.7.13.3 NT chemotaxis protein
KFDAFNOG_00370 1.8e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KFDAFNOG_00371 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KFDAFNOG_00372 1.3e-63 hxlR K transcriptional
KFDAFNOG_00373 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_00374 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_00375 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KFDAFNOG_00376 5.7e-140 srfAD Q thioesterase
KFDAFNOG_00377 3.6e-227 EGP Major Facilitator Superfamily
KFDAFNOG_00378 5.3e-73 S YcxB-like protein
KFDAFNOG_00379 3.8e-160 ycxC EG EamA-like transporter family
KFDAFNOG_00380 4.4e-255 ycxD K GntR family transcriptional regulator
KFDAFNOG_00381 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KFDAFNOG_00382 4.4e-115 yczE S membrane
KFDAFNOG_00383 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KFDAFNOG_00384 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KFDAFNOG_00385 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KFDAFNOG_00386 4.9e-162 bsdA K LysR substrate binding domain
KFDAFNOG_00387 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KFDAFNOG_00388 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KFDAFNOG_00389 4e-39 bsdD 4.1.1.61 S response to toxic substance
KFDAFNOG_00390 1.1e-83 yclD
KFDAFNOG_00391 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
KFDAFNOG_00392 1.5e-267 dtpT E amino acid peptide transporter
KFDAFNOG_00393 2.9e-310 yclG M Pectate lyase superfamily protein
KFDAFNOG_00395 1.8e-279 gerKA EG Spore germination protein
KFDAFNOG_00396 1.3e-232 gerKC S spore germination
KFDAFNOG_00397 6.4e-199 gerKB F Spore germination protein
KFDAFNOG_00398 2.1e-120 yclH P ABC transporter
KFDAFNOG_00399 1.5e-203 yclI V ABC transporter (permease) YclI
KFDAFNOG_00400 4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_00401 4.9e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KFDAFNOG_00402 5.2e-71 S aspartate phosphatase
KFDAFNOG_00406 3.1e-240 lysC 2.7.2.4 E Belongs to the aspartokinase family
KFDAFNOG_00407 7.7e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00408 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00409 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KFDAFNOG_00410 2e-172 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KFDAFNOG_00411 3.2e-251 ycnB EGP Major facilitator Superfamily
KFDAFNOG_00412 1.1e-153 ycnC K Transcriptional regulator
KFDAFNOG_00413 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KFDAFNOG_00414 1.4e-44 ycnE S Monooxygenase
KFDAFNOG_00415 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KFDAFNOG_00416 1.1e-270 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_00417 4.1e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFDAFNOG_00418 4.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KFDAFNOG_00419 6.1e-149 glcU U Glucose uptake
KFDAFNOG_00420 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_00421 2.3e-97 ycnI S protein conserved in bacteria
KFDAFNOG_00422 8.8e-306 ycnJ P protein, homolog of Cu resistance protein CopC
KFDAFNOG_00423 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KFDAFNOG_00424 7.3e-56
KFDAFNOG_00425 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KFDAFNOG_00426 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KFDAFNOG_00427 1.8e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KFDAFNOG_00428 2.1e-199 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KFDAFNOG_00429 2.1e-97 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KFDAFNOG_00430 6.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KFDAFNOG_00431 1.2e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KFDAFNOG_00433 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KFDAFNOG_00434 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
KFDAFNOG_00435 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KFDAFNOG_00436 3.1e-147 ycsI S Belongs to the D-glutamate cyclase family
KFDAFNOG_00437 3.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KFDAFNOG_00438 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KFDAFNOG_00439 6e-132 kipR K Transcriptional regulator
KFDAFNOG_00440 4.9e-119 ycsK E anatomical structure formation involved in morphogenesis
KFDAFNOG_00442 1.4e-49 yczJ S biosynthesis
KFDAFNOG_00443 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KFDAFNOG_00444 2.7e-171 ydhF S Oxidoreductase
KFDAFNOG_00445 0.0 mtlR K transcriptional regulator, MtlR
KFDAFNOG_00446 1.6e-293 ydaB IQ acyl-CoA ligase
KFDAFNOG_00447 1.3e-94 ydaC Q Methyltransferase domain
KFDAFNOG_00448 5e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_00449 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KFDAFNOG_00450 1.1e-98 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KFDAFNOG_00451 6.8e-77 ydaG 1.4.3.5 S general stress protein
KFDAFNOG_00452 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KFDAFNOG_00453 3.3e-46 ydzA EGP Major facilitator Superfamily
KFDAFNOG_00454 2.5e-74 lrpC K Transcriptional regulator
KFDAFNOG_00455 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFDAFNOG_00456 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KFDAFNOG_00457 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
KFDAFNOG_00458 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KFDAFNOG_00459 4.5e-233 ydaM M Glycosyl transferase family group 2
KFDAFNOG_00460 0.0 ydaN S Bacterial cellulose synthase subunit
KFDAFNOG_00461 0.0 ydaO E amino acid
KFDAFNOG_00462 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KFDAFNOG_00463 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KFDAFNOG_00464 2.1e-39
KFDAFNOG_00465 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KFDAFNOG_00467 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KFDAFNOG_00468 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KFDAFNOG_00470 8.9e-59 ydbB G Cupin domain
KFDAFNOG_00471 3.1e-62 ydbC S Domain of unknown function (DUF4937
KFDAFNOG_00472 3.5e-154 ydbD P Catalase
KFDAFNOG_00473 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KFDAFNOG_00474 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KFDAFNOG_00475 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KFDAFNOG_00476 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KFDAFNOG_00477 9.7e-181 ydbI S AI-2E family transporter
KFDAFNOG_00478 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KFDAFNOG_00479 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KFDAFNOG_00480 2.7e-52 ydbL
KFDAFNOG_00481 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KFDAFNOG_00482 1.1e-18 S Fur-regulated basic protein B
KFDAFNOG_00483 2.2e-07 S Fur-regulated basic protein A
KFDAFNOG_00484 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFDAFNOG_00485 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KFDAFNOG_00486 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KFDAFNOG_00487 6.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KFDAFNOG_00488 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KFDAFNOG_00489 2.1e-82 ydbS S Bacterial PH domain
KFDAFNOG_00490 1.1e-259 ydbT S Membrane
KFDAFNOG_00491 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KFDAFNOG_00492 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KFDAFNOG_00493 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KFDAFNOG_00494 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFDAFNOG_00495 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KFDAFNOG_00496 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KFDAFNOG_00497 2.8e-143 rsbR T Positive regulator of sigma-B
KFDAFNOG_00498 5.2e-57 rsbS T antagonist
KFDAFNOG_00499 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KFDAFNOG_00500 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KFDAFNOG_00501 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KFDAFNOG_00502 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KFDAFNOG_00503 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_00504 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KFDAFNOG_00508 1.5e-82 ydcG S EVE domain
KFDAFNOG_00509 6.7e-75 ydcH K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_00510 0.0 yhgF K COG2183 Transcriptional accessory protein
KFDAFNOG_00511 1.6e-84 ydcK S Belongs to the SprT family
KFDAFNOG_00519 1.7e-75 rimJ2 J Acetyltransferase (GNAT) domain
KFDAFNOG_00520 8.5e-45
KFDAFNOG_00521 5.7e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KFDAFNOG_00522 1.7e-32 K Helix-turn-helix XRE-family like proteins
KFDAFNOG_00523 9.6e-40
KFDAFNOG_00527 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KFDAFNOG_00528 8.7e-30 cspL K Cold shock
KFDAFNOG_00529 1.5e-77 carD K Transcription factor
KFDAFNOG_00530 4.4e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KFDAFNOG_00531 1.4e-164 rhaS5 K AraC-like ligand binding domain
KFDAFNOG_00532 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KFDAFNOG_00533 1.4e-164 ydeE K AraC family transcriptional regulator
KFDAFNOG_00534 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_00535 1.8e-216 ydeG EGP Major facilitator superfamily
KFDAFNOG_00536 2.7e-45 ydeH
KFDAFNOG_00537 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KFDAFNOG_00538 1.3e-109
KFDAFNOG_00539 2e-31 S SNARE associated Golgi protein
KFDAFNOG_00540 1.8e-14 ptsH G PTS HPr component phosphorylation site
KFDAFNOG_00541 8.8e-85 K Transcriptional regulator C-terminal region
KFDAFNOG_00542 5.9e-152 ydeK EG -transporter
KFDAFNOG_00543 1.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_00544 4.2e-74 maoC I N-terminal half of MaoC dehydratase
KFDAFNOG_00545 2.8e-105 ydeN S Serine hydrolase
KFDAFNOG_00546 8.2e-41 K HxlR-like helix-turn-helix
KFDAFNOG_00547 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KFDAFNOG_00548 4.8e-69 ydeP K Transcriptional regulator
KFDAFNOG_00549 3.7e-32 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KFDAFNOG_00550 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KFDAFNOG_00551 6.2e-192 ydeR EGP Major facilitator Superfamily
KFDAFNOG_00552 1e-102 ydeS K Transcriptional regulator
KFDAFNOG_00553 6.3e-57 arsR K transcriptional
KFDAFNOG_00554 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFDAFNOG_00555 1.4e-147 ydfB J GNAT acetyltransferase
KFDAFNOG_00556 2.9e-157 ydfC EG EamA-like transporter family
KFDAFNOG_00557 4.2e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_00558 5.9e-117 ydfE S Flavin reductase like domain
KFDAFNOG_00559 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KFDAFNOG_00560 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFDAFNOG_00562 2.2e-68 ydfH 2.7.13.3 T Histidine kinase
KFDAFNOG_00563 3.1e-101 ydfH 2.7.13.3 T Histidine kinase
KFDAFNOG_00564 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_00565 0.0 ydfJ S drug exporters of the RND superfamily
KFDAFNOG_00566 1.9e-177 S Alpha/beta hydrolase family
KFDAFNOG_00567 5.9e-118 S Protein of unknown function (DUF554)
KFDAFNOG_00568 3.2e-147 K Bacterial transcription activator, effector binding domain
KFDAFNOG_00569 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFDAFNOG_00570 9.6e-112 ydfN C nitroreductase
KFDAFNOG_00571 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KFDAFNOG_00572 8.8e-63 mhqP S DoxX
KFDAFNOG_00573 1.3e-57 traF CO Thioredoxin
KFDAFNOG_00574 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KFDAFNOG_00575 6.3e-29
KFDAFNOG_00577 4.4e-118 ydfR S Protein of unknown function (DUF421)
KFDAFNOG_00578 5.2e-122 ydfS S Protein of unknown function (DUF421)
KFDAFNOG_00579 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
KFDAFNOG_00580 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
KFDAFNOG_00581 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KFDAFNOG_00582 3e-94 K Bacterial regulatory proteins, tetR family
KFDAFNOG_00583 1.6e-52 S DoxX-like family
KFDAFNOG_00584 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
KFDAFNOG_00585 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KFDAFNOG_00586 2e-119 purR K helix_turn _helix lactose operon repressor
KFDAFNOG_00587 1e-190 csbC EGP Major facilitator Superfamily
KFDAFNOG_00588 4.4e-104 G Xylose isomerase-like TIM barrel
KFDAFNOG_00589 1.7e-301 expZ S ABC transporter
KFDAFNOG_00590 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_00591 2.3e-90 dinB S DinB family
KFDAFNOG_00592 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_00593 0.0 ydgH S drug exporters of the RND superfamily
KFDAFNOG_00594 8.8e-113 drgA C nitroreductase
KFDAFNOG_00595 2.4e-69 ydgJ K Winged helix DNA-binding domain
KFDAFNOG_00596 4.8e-208 tcaB EGP Major facilitator Superfamily
KFDAFNOG_00597 1.6e-121 ydhB S membrane transporter protein
KFDAFNOG_00598 6.5e-122 ydhC K FCD
KFDAFNOG_00599 6.3e-243 ydhD M Glycosyl hydrolase
KFDAFNOG_00600 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KFDAFNOG_00601 4.2e-127
KFDAFNOG_00602 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KFDAFNOG_00603 8.7e-68 frataxin S Domain of unknown function (DU1801)
KFDAFNOG_00605 1.5e-80 K Acetyltransferase (GNAT) domain
KFDAFNOG_00606 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KFDAFNOG_00607 2.5e-98 ydhK M Protein of unknown function (DUF1541)
KFDAFNOG_00608 4.6e-200 pbuE EGP Major facilitator Superfamily
KFDAFNOG_00609 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KFDAFNOG_00610 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KFDAFNOG_00611 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KFDAFNOG_00612 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KFDAFNOG_00613 1.1e-132 ydhQ K UTRA
KFDAFNOG_00614 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KFDAFNOG_00615 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
KFDAFNOG_00616 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KFDAFNOG_00617 6.1e-157 ydhU P Catalase
KFDAFNOG_00620 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00621 7.8e-08
KFDAFNOG_00623 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFDAFNOG_00624 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KFDAFNOG_00625 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KFDAFNOG_00626 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KFDAFNOG_00627 1.5e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFDAFNOG_00628 0.0 ydiF S ABC transporter
KFDAFNOG_00629 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KFDAFNOG_00630 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KFDAFNOG_00631 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KFDAFNOG_00632 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFDAFNOG_00633 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KFDAFNOG_00634 7.9e-129 ydiL S CAAX protease self-immunity
KFDAFNOG_00635 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFDAFNOG_00636 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KFDAFNOG_00637 5.7e-145 L Belongs to the 'phage' integrase family
KFDAFNOG_00638 6.1e-48 xkdA E IrrE N-terminal-like domain
KFDAFNOG_00639 1.4e-27 S Protein of unknown function (DUF4064)
KFDAFNOG_00640 1.1e-47
KFDAFNOG_00641 1.5e-16 xre K Helix-turn-helix XRE-family like proteins
KFDAFNOG_00642 8.4e-13 K Helix-turn-helix domain
KFDAFNOG_00643 2.6e-33
KFDAFNOG_00644 4e-67 S DNA binding
KFDAFNOG_00645 7.5e-87
KFDAFNOG_00651 5.9e-153 yqaJ L YqaJ-like viral recombinase domain
KFDAFNOG_00652 1.1e-121 recT L RecT family
KFDAFNOG_00653 2.3e-37 3.1.3.16 L DnaD domain protein
KFDAFNOG_00654 1.5e-120 xkdC L IstB-like ATP binding protein
KFDAFNOG_00656 1.3e-07
KFDAFNOG_00657 9.3e-43 S Protein of unknown function (DUF1064)
KFDAFNOG_00659 8.3e-20 yqaO S Phage-like element PBSX protein XtrA
KFDAFNOG_00661 6.9e-26
KFDAFNOG_00672 2.7e-79 L Transposase
KFDAFNOG_00675 1.5e-84 yqaS L DNA packaging
KFDAFNOG_00676 2e-217 S phage terminase, large subunit
KFDAFNOG_00677 6.2e-207 S Phage portal protein, SPP1 Gp6-like
KFDAFNOG_00678 5e-80 S Phage Mu protein F like protein
KFDAFNOG_00681 6.8e-59 S Domain of unknown function (DUF4355)
KFDAFNOG_00682 5e-141 S Phage capsid family
KFDAFNOG_00685 3.8e-29 S Phage gp6-like head-tail connector protein
KFDAFNOG_00686 8.2e-28 S Phage head-tail joining protein
KFDAFNOG_00687 1.5e-36 S Bacteriophage HK97-gp10, putative tail-component
KFDAFNOG_00688 2.3e-29 S Protein of unknown function (DUF3168)
KFDAFNOG_00689 3e-34 S Phage tail tube protein
KFDAFNOG_00690 8.4e-29 S Phage tail assembly chaperone protein, TAC
KFDAFNOG_00691 1.7e-139
KFDAFNOG_00692 1.2e-50
KFDAFNOG_00693 8.2e-221 S peptidoglycan catabolic process
KFDAFNOG_00698 7.3e-27 xhlA S Haemolysin XhlA
KFDAFNOG_00699 3.9e-30 xhlB S SPP1 phage holin
KFDAFNOG_00701 2.8e-139 xlyB 3.5.1.28 CBM50 MT N-acetylmuramoyl-L-alanine amidase
KFDAFNOG_00703 1.2e-27 K Helix-turn-helix domain
KFDAFNOG_00704 4.9e-39
KFDAFNOG_00706 8.8e-32 U Preprotein translocase subunit SecB
KFDAFNOG_00707 4.8e-14
KFDAFNOG_00709 6.4e-66 KL Phage plasmid primase P4 family
KFDAFNOG_00710 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
KFDAFNOG_00711 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
KFDAFNOG_00713 1.2e-199 V AAA domain (dynein-related subfamily)
KFDAFNOG_00714 4.9e-257 J LlaJI restriction endonuclease
KFDAFNOG_00715 1.1e-08 ydjC S Abhydrolase domain containing 18
KFDAFNOG_00716 0.0 K NB-ARC domain
KFDAFNOG_00717 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
KFDAFNOG_00718 7.1e-256 gutA G MFS/sugar transport protein
KFDAFNOG_00719 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KFDAFNOG_00720 5.1e-114 pspA KT Phage shock protein A
KFDAFNOG_00721 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFDAFNOG_00722 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KFDAFNOG_00723 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
KFDAFNOG_00724 4.7e-196 S Ion transport 2 domain protein
KFDAFNOG_00725 2.7e-258 iolT EGP Major facilitator Superfamily
KFDAFNOG_00726 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KFDAFNOG_00727 4.5e-64 ydjM M Lytic transglycolase
KFDAFNOG_00728 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
KFDAFNOG_00730 1.4e-34 ydjO S Cold-inducible protein YdjO
KFDAFNOG_00731 8.4e-156 ydjP I Alpha/beta hydrolase family
KFDAFNOG_00732 3.3e-175 yeaA S Protein of unknown function (DUF4003)
KFDAFNOG_00733 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KFDAFNOG_00734 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_00735 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFDAFNOG_00736 1.5e-175 yeaC S COG0714 MoxR-like ATPases
KFDAFNOG_00737 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KFDAFNOG_00738 0.0 yebA E COG1305 Transglutaminase-like enzymes
KFDAFNOG_00739 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KFDAFNOG_00740 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_00741 9.8e-256 S Domain of unknown function (DUF4179)
KFDAFNOG_00742 7.8e-212 pbuG S permease
KFDAFNOG_00743 8.3e-116 yebC M Membrane
KFDAFNOG_00745 8.9e-93 yebE S UPF0316 protein
KFDAFNOG_00746 8e-28 yebG S NETI protein
KFDAFNOG_00747 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFDAFNOG_00748 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFDAFNOG_00749 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KFDAFNOG_00750 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KFDAFNOG_00751 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFDAFNOG_00752 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFDAFNOG_00753 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFDAFNOG_00754 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KFDAFNOG_00755 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KFDAFNOG_00756 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFDAFNOG_00757 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KFDAFNOG_00758 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
KFDAFNOG_00759 3.5e-73 K helix_turn_helix ASNC type
KFDAFNOG_00760 6.4e-227 yjeH E Amino acid permease
KFDAFNOG_00761 2.7e-27 S Protein of unknown function (DUF2892)
KFDAFNOG_00762 0.0 yerA 3.5.4.2 F adenine deaminase
KFDAFNOG_00763 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
KFDAFNOG_00764 4.8e-51 yerC S protein conserved in bacteria
KFDAFNOG_00765 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KFDAFNOG_00766 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KFDAFNOG_00767 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KFDAFNOG_00768 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFDAFNOG_00769 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KFDAFNOG_00770 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
KFDAFNOG_00771 6.1e-123 sapB S MgtC SapB transporter
KFDAFNOG_00772 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFDAFNOG_00773 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFDAFNOG_00774 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KFDAFNOG_00775 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFDAFNOG_00776 1.3e-148 yerO K Transcriptional regulator
KFDAFNOG_00777 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFDAFNOG_00778 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KFDAFNOG_00779 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFDAFNOG_00780 0.0 L Type III restriction enzyme res subunit
KFDAFNOG_00782 5.8e-43
KFDAFNOG_00784 1.4e-100 S response regulator aspartate phosphatase
KFDAFNOG_00786 2.7e-27
KFDAFNOG_00787 4.2e-75 S Protein of unknown function, DUF600
KFDAFNOG_00788 0.0 L nucleic acid phosphodiester bond hydrolysis
KFDAFNOG_00790 8.7e-101 L endonuclease activity
KFDAFNOG_00791 2e-125 3.4.24.40 CO amine dehydrogenase activity
KFDAFNOG_00792 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
KFDAFNOG_00793 1e-39
KFDAFNOG_00794 4.1e-209 S Tetratricopeptide repeat
KFDAFNOG_00796 2.7e-126 yeeN K transcriptional regulatory protein
KFDAFNOG_00798 8.5e-102 dhaR3 K Transcriptional regulator
KFDAFNOG_00799 2.5e-77 yesE S SnoaL-like domain
KFDAFNOG_00800 5.5e-142 yesF GM NAD(P)H-binding
KFDAFNOG_00801 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KFDAFNOG_00802 1.5e-45 cotJB S CotJB protein
KFDAFNOG_00803 5.2e-104 cotJC P Spore Coat
KFDAFNOG_00804 1.3e-101 yesJ K Acetyltransferase (GNAT) family
KFDAFNOG_00805 1.2e-101 yesL S Protein of unknown function, DUF624
KFDAFNOG_00806 0.0 yesM 2.7.13.3 T Histidine kinase
KFDAFNOG_00807 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
KFDAFNOG_00808 1.6e-246 yesO G Bacterial extracellular solute-binding protein
KFDAFNOG_00809 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
KFDAFNOG_00810 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
KFDAFNOG_00811 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KFDAFNOG_00812 0.0 yesS K Transcriptional regulator
KFDAFNOG_00813 6.1e-131 E GDSL-like Lipase/Acylhydrolase
KFDAFNOG_00814 2.1e-128 yesU S Domain of unknown function (DUF1961)
KFDAFNOG_00815 1.5e-112 yesV S Protein of unknown function, DUF624
KFDAFNOG_00816 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KFDAFNOG_00817 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KFDAFNOG_00818 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
KFDAFNOG_00819 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KFDAFNOG_00820 0.0 yetA
KFDAFNOG_00821 1.7e-287 lplA G Bacterial extracellular solute-binding protein
KFDAFNOG_00822 1.9e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KFDAFNOG_00823 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KFDAFNOG_00824 3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KFDAFNOG_00825 8.8e-122 yetF S membrane
KFDAFNOG_00826 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KFDAFNOG_00827 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_00828 2.6e-34
KFDAFNOG_00829 1.6e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KFDAFNOG_00830 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KFDAFNOG_00831 3.4e-104 yetJ S Belongs to the BI1 family
KFDAFNOG_00832 4.6e-88 yetL K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_00833 4e-209 yetM CH FAD binding domain
KFDAFNOG_00834 3.6e-199 yetN S Protein of unknown function (DUF3900)
KFDAFNOG_00835 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KFDAFNOG_00836 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KFDAFNOG_00837 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KFDAFNOG_00838 1.9e-172 yfnG 4.2.1.45 M dehydratase
KFDAFNOG_00839 2.4e-180 yfnF M Nucleotide-diphospho-sugar transferase
KFDAFNOG_00840 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KFDAFNOG_00841 1e-189 yfnD M Nucleotide-diphospho-sugar transferase
KFDAFNOG_00842 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
KFDAFNOG_00843 6.2e-131 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KFDAFNOG_00844 1.4e-240 yfnA E amino acid
KFDAFNOG_00845 3.7e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KFDAFNOG_00846 1.1e-113 yfmS NT chemotaxis protein
KFDAFNOG_00847 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KFDAFNOG_00848 3.1e-72 yfmQ S Uncharacterised protein from bacillus cereus group
KFDAFNOG_00849 1.4e-69 yfmP K transcriptional
KFDAFNOG_00850 1.5e-209 yfmO EGP Major facilitator Superfamily
KFDAFNOG_00851 8.6e-37
KFDAFNOG_00852 1.2e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KFDAFNOG_00853 5.5e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KFDAFNOG_00854 3.5e-79 yfmK 2.3.1.128 K acetyltransferase
KFDAFNOG_00855 3.2e-189 yfmJ S N-terminal domain of oxidoreductase
KFDAFNOG_00856 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KFDAFNOG_00857 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00858 5.3e-168 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00859 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KFDAFNOG_00860 5e-24 S Protein of unknown function (DUF3212)
KFDAFNOG_00861 7.6e-58 yflT S Heat induced stress protein YflT
KFDAFNOG_00862 8.5e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KFDAFNOG_00863 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
KFDAFNOG_00864 5.7e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KFDAFNOG_00865 2.9e-117 citT T response regulator
KFDAFNOG_00866 3.7e-179 yflP S Tripartite tricarboxylate transporter family receptor
KFDAFNOG_00867 8.5e-227 citM C Citrate transporter
KFDAFNOG_00868 1.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KFDAFNOG_00869 8.7e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KFDAFNOG_00870 1.9e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KFDAFNOG_00871 1.7e-122 yflK S protein conserved in bacteria
KFDAFNOG_00872 8.9e-18 yflJ S Protein of unknown function (DUF2639)
KFDAFNOG_00873 1.6e-18 yflI
KFDAFNOG_00874 5.3e-50 yflH S Protein of unknown function (DUF3243)
KFDAFNOG_00875 3.2e-138 map 3.4.11.18 E Methionine aminopeptidase
KFDAFNOG_00876 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KFDAFNOG_00877 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KFDAFNOG_00878 6e-67 yhdN S Domain of unknown function (DUF1992)
KFDAFNOG_00879 3.1e-251 agcS_1 E Sodium alanine symporter
KFDAFNOG_00880 8.4e-25 yfkQ EG Spore germination protein
KFDAFNOG_00881 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_00882 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KFDAFNOG_00883 5.1e-133 treR K transcriptional
KFDAFNOG_00884 1.8e-124 yfkO C nitroreductase
KFDAFNOG_00885 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KFDAFNOG_00886 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
KFDAFNOG_00887 6.8e-207 ydiM EGP Major facilitator Superfamily
KFDAFNOG_00888 1.3e-28 yfkK S Belongs to the UPF0435 family
KFDAFNOG_00889 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFDAFNOG_00890 1.2e-49 yfkI S gas vesicle protein
KFDAFNOG_00891 4.8e-143 yihY S Belongs to the UPF0761 family
KFDAFNOG_00892 5e-08
KFDAFNOG_00893 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KFDAFNOG_00894 1.8e-182 cax P COG0387 Ca2 H antiporter
KFDAFNOG_00895 1.2e-146 yfkD S YfkD-like protein
KFDAFNOG_00896 6e-149 yfkC M Mechanosensitive ion channel
KFDAFNOG_00897 5.4e-222 yfkA S YfkB-like domain
KFDAFNOG_00898 1.1e-26 yfjT
KFDAFNOG_00899 1.7e-153 pdaA G deacetylase
KFDAFNOG_00900 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KFDAFNOG_00901 1.7e-184 corA P Mediates influx of magnesium ions
KFDAFNOG_00902 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KFDAFNOG_00903 2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFDAFNOG_00904 1.6e-39 S YfzA-like protein
KFDAFNOG_00905 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFDAFNOG_00906 1.1e-83 yfjM S Psort location Cytoplasmic, score
KFDAFNOG_00907 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KFDAFNOG_00908 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KFDAFNOG_00909 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KFDAFNOG_00910 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KFDAFNOG_00911 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KFDAFNOG_00912 9.8e-25 sspH S Belongs to the SspH family
KFDAFNOG_00913 4e-56 yfjF S UPF0060 membrane protein
KFDAFNOG_00914 1.1e-79 S Family of unknown function (DUF5381)
KFDAFNOG_00915 1.8e-101 yfjD S Family of unknown function (DUF5381)
KFDAFNOG_00916 4.5e-143 yfjC
KFDAFNOG_00917 9.2e-191 yfjB
KFDAFNOG_00918 7.4e-44 yfjA S Belongs to the WXG100 family
KFDAFNOG_00919 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KFDAFNOG_00920 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
KFDAFNOG_00921 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_00922 8.4e-307 yfiB3 V ABC transporter
KFDAFNOG_00923 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KFDAFNOG_00924 6.4e-64 mhqP S DoxX
KFDAFNOG_00925 5.7e-163 yfiE 1.13.11.2 S glyoxalase
KFDAFNOG_00926 1.5e-177 K AraC-like ligand binding domain
KFDAFNOG_00927 1.8e-262 iolT EGP Major facilitator Superfamily
KFDAFNOG_00928 8.4e-184 G Xylose isomerase
KFDAFNOG_00929 1.1e-233 S Oxidoreductase
KFDAFNOG_00931 1.8e-212 yxjM T Histidine kinase
KFDAFNOG_00932 6e-112 KT LuxR family transcriptional regulator
KFDAFNOG_00933 2.4e-167 V ABC transporter, ATP-binding protein
KFDAFNOG_00934 8.1e-208 V ABC-2 family transporter protein
KFDAFNOG_00935 3.2e-201 V COG0842 ABC-type multidrug transport system, permease component
KFDAFNOG_00936 8.3e-99 padR K transcriptional
KFDAFNOG_00937 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KFDAFNOG_00938 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KFDAFNOG_00939 7.1e-107 yfiR K Transcriptional regulator
KFDAFNOG_00940 1.5e-209 yfiS EGP Major facilitator Superfamily
KFDAFNOG_00941 4.8e-78 yfiT S Belongs to the metal hydrolase YfiT family
KFDAFNOG_00942 6.9e-284 yfiU EGP Major facilitator Superfamily
KFDAFNOG_00943 4.9e-79 yfiV K transcriptional
KFDAFNOG_00944 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KFDAFNOG_00945 3.9e-176 yfiY P ABC transporter substrate-binding protein
KFDAFNOG_00946 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00947 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_00948 4e-164 yfhB 5.3.3.17 S PhzF family
KFDAFNOG_00949 1.5e-106 yfhC C nitroreductase
KFDAFNOG_00950 2.1e-25 yfhD S YfhD-like protein
KFDAFNOG_00952 1.4e-172 yfhF S nucleoside-diphosphate sugar epimerase
KFDAFNOG_00953 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
KFDAFNOG_00954 9.7e-52 yfhH S Protein of unknown function (DUF1811)
KFDAFNOG_00956 1.1e-209 yfhI EGP Major facilitator Superfamily
KFDAFNOG_00957 6.2e-20 sspK S reproduction
KFDAFNOG_00958 2.9e-44 yfhJ S WVELL protein
KFDAFNOG_00959 1.3e-90 batE T Bacterial SH3 domain homologues
KFDAFNOG_00960 3e-47 yfhL S SdpI/YhfL protein family
KFDAFNOG_00961 1.3e-170 yfhM S Alpha beta hydrolase
KFDAFNOG_00962 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KFDAFNOG_00963 0.0 yfhO S Bacterial membrane protein YfhO
KFDAFNOG_00964 5.5e-186 yfhP S membrane-bound metal-dependent
KFDAFNOG_00965 8.6e-212 mutY L A G-specific
KFDAFNOG_00966 6.9e-36 yfhS
KFDAFNOG_00967 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_00968 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KFDAFNOG_00969 1.5e-37 ygaB S YgaB-like protein
KFDAFNOG_00970 1.3e-104 ygaC J Belongs to the UPF0374 family
KFDAFNOG_00971 1.8e-301 ygaD V ABC transporter
KFDAFNOG_00972 8.7e-180 ygaE S Membrane
KFDAFNOG_00973 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KFDAFNOG_00974 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
KFDAFNOG_00975 4e-80 perR P Belongs to the Fur family
KFDAFNOG_00976 1.1e-54 ygzB S UPF0295 protein
KFDAFNOG_00977 3.3e-166 ygxA S Nucleotidyltransferase-like
KFDAFNOG_00978 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_00983 7.8e-08
KFDAFNOG_00991 2e-08
KFDAFNOG_00995 2.7e-143 spo0M S COG4326 Sporulation control protein
KFDAFNOG_00996 1.2e-26
KFDAFNOG_00997 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KFDAFNOG_00998 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFDAFNOG_00999 1.9e-266 ygaK C Berberine and berberine like
KFDAFNOG_01001 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KFDAFNOG_01002 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KFDAFNOG_01003 1.7e-171 ssuA M Sulfonate ABC transporter
KFDAFNOG_01004 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KFDAFNOG_01005 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KFDAFNOG_01007 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFDAFNOG_01008 4.1e-78 ygaO
KFDAFNOG_01009 4.4e-29 K Transcriptional regulator
KFDAFNOG_01011 7.9e-114 yhzB S B3/4 domain
KFDAFNOG_01012 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFDAFNOG_01013 4.4e-177 yhbB S Putative amidase domain
KFDAFNOG_01014 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KFDAFNOG_01015 1.2e-109 yhbD K Protein of unknown function (DUF4004)
KFDAFNOG_01016 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KFDAFNOG_01017 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KFDAFNOG_01018 0.0 prkA T Ser protein kinase
KFDAFNOG_01019 2.5e-225 yhbH S Belongs to the UPF0229 family
KFDAFNOG_01020 2.2e-76 yhbI K DNA-binding transcription factor activity
KFDAFNOG_01021 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KFDAFNOG_01022 3.1e-271 yhcA EGP Major facilitator Superfamily
KFDAFNOG_01023 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KFDAFNOG_01024 2.8e-37 yhcC
KFDAFNOG_01025 2e-55
KFDAFNOG_01026 6.6e-60 yhcF K Transcriptional regulator
KFDAFNOG_01027 1.6e-123 yhcG V ABC transporter, ATP-binding protein
KFDAFNOG_01028 7.7e-166 yhcH V ABC transporter, ATP-binding protein
KFDAFNOG_01029 5.6e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KFDAFNOG_01030 1e-30 cspB K Cold-shock protein
KFDAFNOG_01031 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
KFDAFNOG_01032 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KFDAFNOG_01033 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KFDAFNOG_01034 1.1e-77 S Protein of unknown function (DUF2812)
KFDAFNOG_01035 1.2e-49 K Transcriptional regulator PadR-like family
KFDAFNOG_01036 2e-41 yhcM
KFDAFNOG_01037 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KFDAFNOG_01038 1.3e-166 yhcP
KFDAFNOG_01039 4.4e-99 yhcQ M Spore coat protein
KFDAFNOG_01040 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KFDAFNOG_01041 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KFDAFNOG_01042 7.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KFDAFNOG_01043 2.1e-67 yhcU S Family of unknown function (DUF5365)
KFDAFNOG_01044 9.9e-68 yhcV S COG0517 FOG CBS domain
KFDAFNOG_01045 1.3e-119 yhcW 5.4.2.6 S hydrolase
KFDAFNOG_01046 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KFDAFNOG_01047 4.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFDAFNOG_01048 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KFDAFNOG_01049 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KFDAFNOG_01050 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFDAFNOG_01051 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFDAFNOG_01052 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KFDAFNOG_01053 2.8e-210 yhcY 2.7.13.3 T Histidine kinase
KFDAFNOG_01054 7.7e-112 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_01055 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
KFDAFNOG_01056 1.2e-38 yhdB S YhdB-like protein
KFDAFNOG_01057 4.8e-54 yhdC S Protein of unknown function (DUF3889)
KFDAFNOG_01058 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KFDAFNOG_01059 1e-75 nsrR K Transcriptional regulator
KFDAFNOG_01060 1.3e-237 ygxB M Conserved TM helix
KFDAFNOG_01061 6.3e-276 ycgB S Stage V sporulation protein R
KFDAFNOG_01062 1.6e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KFDAFNOG_01063 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KFDAFNOG_01064 1.1e-161 citR K Transcriptional regulator
KFDAFNOG_01065 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
KFDAFNOG_01066 3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_01067 3.4e-250 yhdG E amino acid
KFDAFNOG_01068 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KFDAFNOG_01069 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_01070 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_01071 8.1e-45 yhdK S Sigma-M inhibitor protein
KFDAFNOG_01072 6.6e-201 yhdL S Sigma factor regulator N-terminal
KFDAFNOG_01073 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_01074 2.2e-190 yhdN C Aldo keto reductase
KFDAFNOG_01075 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KFDAFNOG_01076 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KFDAFNOG_01077 4.1e-74 cueR K transcriptional
KFDAFNOG_01078 1.4e-220 yhdR 2.6.1.1 E Aminotransferase
KFDAFNOG_01079 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KFDAFNOG_01080 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFDAFNOG_01081 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFDAFNOG_01082 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KFDAFNOG_01084 1.6e-202 yhdY M Mechanosensitive ion channel
KFDAFNOG_01085 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KFDAFNOG_01086 5.3e-137 yheN G deacetylase
KFDAFNOG_01087 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KFDAFNOG_01088 3.7e-225 nhaC C Na H antiporter
KFDAFNOG_01089 5.4e-82 nhaX T Belongs to the universal stress protein A family
KFDAFNOG_01090 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KFDAFNOG_01091 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KFDAFNOG_01092 7.6e-109 yheG GM NAD(P)H-binding
KFDAFNOG_01093 6.3e-28 sspB S spore protein
KFDAFNOG_01094 1.3e-36 yheE S Family of unknown function (DUF5342)
KFDAFNOG_01095 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KFDAFNOG_01096 4.3e-216 yheC HJ YheC/D like ATP-grasp
KFDAFNOG_01097 1.8e-201 yheB S Belongs to the UPF0754 family
KFDAFNOG_01098 9.5e-48 yheA S Belongs to the UPF0342 family
KFDAFNOG_01099 3.1e-206 yhaZ L DNA alkylation repair enzyme
KFDAFNOG_01100 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KFDAFNOG_01101 3.9e-292 hemZ H coproporphyrinogen III oxidase
KFDAFNOG_01102 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
KFDAFNOG_01103 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KFDAFNOG_01105 3.2e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
KFDAFNOG_01106 1.1e-26 S YhzD-like protein
KFDAFNOG_01107 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KFDAFNOG_01108 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KFDAFNOG_01109 5.7e-225 yhaO L DNA repair exonuclease
KFDAFNOG_01110 0.0 yhaN L AAA domain
KFDAFNOG_01111 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KFDAFNOG_01112 1.6e-21 yhaL S Sporulation protein YhaL
KFDAFNOG_01113 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KFDAFNOG_01114 7.3e-89 yhaK S Putative zincin peptidase
KFDAFNOG_01115 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KFDAFNOG_01116 2.3e-113 hpr K Negative regulator of protease production and sporulation
KFDAFNOG_01117 7e-39 yhaH S YtxH-like protein
KFDAFNOG_01118 5.4e-21
KFDAFNOG_01119 3.1e-79 trpP S Tryptophan transporter TrpP
KFDAFNOG_01120 3.2e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFDAFNOG_01121 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KFDAFNOG_01122 4.6e-137 ecsA V transporter (ATP-binding protein)
KFDAFNOG_01123 1.6e-214 ecsB U ABC transporter
KFDAFNOG_01124 1.4e-114 ecsC S EcsC protein family
KFDAFNOG_01125 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KFDAFNOG_01126 1.9e-245 yhfA C membrane
KFDAFNOG_01127 2.6e-17 1.15.1.2 C Rubrerythrin
KFDAFNOG_01128 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KFDAFNOG_01129 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KFDAFNOG_01130 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFDAFNOG_01131 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KFDAFNOG_01132 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KFDAFNOG_01133 5.4e-101 yhgD K Transcriptional regulator
KFDAFNOG_01134 8.6e-238 yhgE S YhgE Pip N-terminal domain protein
KFDAFNOG_01135 8.1e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFDAFNOG_01136 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
KFDAFNOG_01137 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KFDAFNOG_01138 1.7e-72 3.4.13.21 S ASCH
KFDAFNOG_01139 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KFDAFNOG_01140 5.2e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KFDAFNOG_01141 4.9e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KFDAFNOG_01142 1.1e-110 yhfK GM NmrA-like family
KFDAFNOG_01143 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KFDAFNOG_01144 1.9e-65 yhfM
KFDAFNOG_01145 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
KFDAFNOG_01146 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KFDAFNOG_01147 3.1e-75 VY92_01935 K acetyltransferase
KFDAFNOG_01148 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
KFDAFNOG_01149 4.3e-159 yfmC M Periplasmic binding protein
KFDAFNOG_01150 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KFDAFNOG_01151 1.6e-194 vraB 2.3.1.9 I Belongs to the thiolase family
KFDAFNOG_01152 1.9e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KFDAFNOG_01153 1.9e-90 bioY S BioY family
KFDAFNOG_01154 1.7e-182 hemAT NT chemotaxis protein
KFDAFNOG_01155 4e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KFDAFNOG_01156 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_01157 1.3e-32 yhzC S IDEAL
KFDAFNOG_01158 4.2e-109 comK K Competence transcription factor
KFDAFNOG_01159 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_01160 7.8e-42 yhjA S Excalibur calcium-binding domain
KFDAFNOG_01161 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFDAFNOG_01162 6.9e-27 yhjC S Protein of unknown function (DUF3311)
KFDAFNOG_01163 6.7e-60 yhjD
KFDAFNOG_01164 3.4e-109 yhjE S SNARE associated Golgi protein
KFDAFNOG_01165 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KFDAFNOG_01166 2.4e-278 yhjG CH FAD binding domain
KFDAFNOG_01167 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_01168 4.5e-214 glcP G Major Facilitator Superfamily
KFDAFNOG_01169 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KFDAFNOG_01170 4.5e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KFDAFNOG_01171 7.7e-252 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KFDAFNOG_01172 5.9e-188 yhjM 5.1.1.1 K Transcriptional regulator
KFDAFNOG_01173 4.2e-201 abrB S membrane
KFDAFNOG_01174 1.9e-212 EGP Transmembrane secretion effector
KFDAFNOG_01175 0.0 S Sugar transport-related sRNA regulator N-term
KFDAFNOG_01176 1e-32 yhjQ C COG1145 Ferredoxin
KFDAFNOG_01177 2.2e-78 yhjR S Rubrerythrin
KFDAFNOG_01178 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KFDAFNOG_01179 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KFDAFNOG_01180 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KFDAFNOG_01181 0.0 sbcC L COG0419 ATPase involved in DNA repair
KFDAFNOG_01182 1.1e-49 yisB V COG1403 Restriction endonuclease
KFDAFNOG_01183 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KFDAFNOG_01184 3e-66 gerPE S Spore germination protein GerPE
KFDAFNOG_01185 6.3e-24 gerPD S Spore germination protein
KFDAFNOG_01186 1.8e-54 gerPC S Spore germination protein
KFDAFNOG_01187 4e-34 gerPB S cell differentiation
KFDAFNOG_01188 1.9e-33 gerPA S Spore germination protein
KFDAFNOG_01189 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KFDAFNOG_01190 1.1e-172 cotH M Spore Coat
KFDAFNOG_01191 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KFDAFNOG_01192 3.9e-57 yisL S UPF0344 protein
KFDAFNOG_01193 0.0 wprA O Belongs to the peptidase S8 family
KFDAFNOG_01194 2.1e-102 yisN S Protein of unknown function (DUF2777)
KFDAFNOG_01195 0.0 asnO 6.3.5.4 E Asparagine synthase
KFDAFNOG_01196 3.9e-87 yizA S Damage-inducible protein DinB
KFDAFNOG_01197 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KFDAFNOG_01198 6.2e-160 yisQ V Mate efflux family protein
KFDAFNOG_01199 2.1e-71 yisQ V Mate efflux family protein
KFDAFNOG_01200 1.2e-160 yisR K Transcriptional regulator
KFDAFNOG_01201 1.5e-183 purR K helix_turn _helix lactose operon repressor
KFDAFNOG_01202 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KFDAFNOG_01203 7e-92 yisT S DinB family
KFDAFNOG_01204 1.9e-107 argO S Lysine exporter protein LysE YggA
KFDAFNOG_01205 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KFDAFNOG_01206 4e-36 mcbG S Pentapeptide repeats (9 copies)
KFDAFNOG_01207 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KFDAFNOG_01208 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KFDAFNOG_01209 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KFDAFNOG_01210 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KFDAFNOG_01211 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
KFDAFNOG_01212 5.4e-141 yitD 4.4.1.19 S synthase
KFDAFNOG_01213 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFDAFNOG_01214 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KFDAFNOG_01215 1.5e-228 yitG EGP Major facilitator Superfamily
KFDAFNOG_01216 2e-160 yitH K Acetyltransferase (GNAT) domain
KFDAFNOG_01217 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
KFDAFNOG_01218 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KFDAFNOG_01219 5.6e-54 yajQ S Belongs to the UPF0234 family
KFDAFNOG_01220 6.9e-161 cvfB S protein conserved in bacteria
KFDAFNOG_01221 8.5e-94
KFDAFNOG_01222 1.4e-170
KFDAFNOG_01223 1.5e-97 S Sporulation delaying protein SdpA
KFDAFNOG_01224 1.5e-58 K Transcriptional regulator PadR-like family
KFDAFNOG_01225 2e-95
KFDAFNOG_01226 1.4e-44 yitR S Domain of unknown function (DUF3784)
KFDAFNOG_01227 2.2e-311 nprB 3.4.24.28 E Peptidase M4
KFDAFNOG_01228 8.4e-159 yitS S protein conserved in bacteria
KFDAFNOG_01229 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KFDAFNOG_01230 5e-73 ipi S Intracellular proteinase inhibitor
KFDAFNOG_01231 1.2e-17 S Protein of unknown function (DUF3813)
KFDAFNOG_01232 7.8e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KFDAFNOG_01233 1e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KFDAFNOG_01234 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KFDAFNOG_01235 1.5e-22 pilT S Proteolipid membrane potential modulator
KFDAFNOG_01236 6e-266 yitY C D-arabinono-1,4-lactone oxidase
KFDAFNOG_01237 1.7e-88 norB G Major Facilitator Superfamily
KFDAFNOG_01238 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFDAFNOG_01239 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFDAFNOG_01240 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KFDAFNOG_01241 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KFDAFNOG_01242 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KFDAFNOG_01243 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KFDAFNOG_01244 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KFDAFNOG_01245 9.5e-28 yjzC S YjzC-like protein
KFDAFNOG_01246 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KFDAFNOG_01247 6.8e-141 yjaU I carboxylic ester hydrolase activity
KFDAFNOG_01248 1.8e-101 yjaV
KFDAFNOG_01249 1.1e-183 med S Transcriptional activator protein med
KFDAFNOG_01250 4.7e-25 comZ S ComZ
KFDAFNOG_01251 2.7e-22 yjzB
KFDAFNOG_01252 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFDAFNOG_01253 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KFDAFNOG_01254 7.8e-151 yjaZ O Zn-dependent protease
KFDAFNOG_01255 1.8e-184 appD P Belongs to the ABC transporter superfamily
KFDAFNOG_01256 6.5e-187 appF E Belongs to the ABC transporter superfamily
KFDAFNOG_01257 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KFDAFNOG_01258 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01259 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01260 6.5e-147 yjbA S Belongs to the UPF0736 family
KFDAFNOG_01261 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KFDAFNOG_01262 0.0 oppA E ABC transporter substrate-binding protein
KFDAFNOG_01263 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01264 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01265 1.5e-197 oppD P Belongs to the ABC transporter superfamily
KFDAFNOG_01266 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KFDAFNOG_01267 1.8e-210 yjbB EGP Major Facilitator Superfamily
KFDAFNOG_01268 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_01269 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KFDAFNOG_01270 6e-112 yjbE P Integral membrane protein TerC family
KFDAFNOG_01271 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KFDAFNOG_01272 2.1e-221 yjbF S Competence protein
KFDAFNOG_01273 0.0 pepF E oligoendopeptidase F
KFDAFNOG_01274 1.8e-20
KFDAFNOG_01276 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KFDAFNOG_01277 1.1e-71 yjbI S Bacterial-like globin
KFDAFNOG_01278 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KFDAFNOG_01279 1e-99 yjbK S protein conserved in bacteria
KFDAFNOG_01280 1.6e-61 yjbL S Belongs to the UPF0738 family
KFDAFNOG_01281 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KFDAFNOG_01282 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFDAFNOG_01283 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KFDAFNOG_01284 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KFDAFNOG_01285 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KFDAFNOG_01286 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KFDAFNOG_01287 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KFDAFNOG_01288 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
KFDAFNOG_01289 2.6e-29 thiS H thiamine diphosphate biosynthetic process
KFDAFNOG_01290 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KFDAFNOG_01291 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KFDAFNOG_01292 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KFDAFNOG_01293 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KFDAFNOG_01294 5.9e-54 yjbX S Spore coat protein
KFDAFNOG_01295 4.4e-82 cotZ S Spore coat protein
KFDAFNOG_01296 7.6e-96 cotY S Spore coat protein Z
KFDAFNOG_01297 1.6e-72 cotX S Spore Coat Protein X and V domain
KFDAFNOG_01298 8.8e-24 cotW
KFDAFNOG_01299 1.1e-54 cotV S Spore Coat Protein X and V domain
KFDAFNOG_01300 4.3e-56 yjcA S Protein of unknown function (DUF1360)
KFDAFNOG_01303 2.9e-38 spoVIF S Stage VI sporulation protein F
KFDAFNOG_01304 0.0 yjcD 3.6.4.12 L DNA helicase
KFDAFNOG_01305 1.7e-38
KFDAFNOG_01306 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_01307 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KFDAFNOG_01308 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
KFDAFNOG_01309 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KFDAFNOG_01310 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KFDAFNOG_01311 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
KFDAFNOG_01312 1.3e-210 yjcL S Protein of unknown function (DUF819)
KFDAFNOG_01315 7.8e-190 S Putative amidase domain
KFDAFNOG_01316 2.6e-44 yjcN
KFDAFNOG_01319 8.5e-81 L Transposase
KFDAFNOG_01320 5.3e-71 yjcP
KFDAFNOG_01321 4.1e-49 S YjcQ protein
KFDAFNOG_01322 1.1e-92 yqaS L DNA packaging
KFDAFNOG_01323 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
KFDAFNOG_01324 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_01326 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KFDAFNOG_01327 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KFDAFNOG_01328 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
KFDAFNOG_01329 4.5e-49 yjdF S Protein of unknown function (DUF2992)
KFDAFNOG_01330 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KFDAFNOG_01332 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KFDAFNOG_01333 4.2e-29 S Domain of unknown function (DUF4177)
KFDAFNOG_01334 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
KFDAFNOG_01335 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KFDAFNOG_01337 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
KFDAFNOG_01338 1.4e-81 S Protein of unknown function (DUF2690)
KFDAFNOG_01339 8.9e-20 yjfB S Putative motility protein
KFDAFNOG_01340 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
KFDAFNOG_01341 1.2e-45 T PhoQ Sensor
KFDAFNOG_01342 8.9e-104 yjgB S Domain of unknown function (DUF4309)
KFDAFNOG_01343 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KFDAFNOG_01344 4.3e-95 yjgD S Protein of unknown function (DUF1641)
KFDAFNOG_01345 8.7e-07 S Domain of unknown function (DUF4352)
KFDAFNOG_01346 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KFDAFNOG_01348 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KFDAFNOG_01349 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KFDAFNOG_01350 8.2e-30
KFDAFNOG_01351 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KFDAFNOG_01352 5.6e-122 ybbM S transport system, permease component
KFDAFNOG_01353 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KFDAFNOG_01354 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
KFDAFNOG_01355 6.4e-90 yjlB S Cupin domain
KFDAFNOG_01356 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KFDAFNOG_01357 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KFDAFNOG_01358 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
KFDAFNOG_01359 5.8e-250 yjmB G symporter YjmB
KFDAFNOG_01360 4.3e-194 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KFDAFNOG_01361 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KFDAFNOG_01362 2.3e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KFDAFNOG_01363 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_01364 3.7e-227 exuT G Sugar (and other) transporter
KFDAFNOG_01365 2.3e-184 exuR K transcriptional
KFDAFNOG_01366 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KFDAFNOG_01367 4.6e-285 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KFDAFNOG_01368 7.4e-130 MA20_18170 S membrane transporter protein
KFDAFNOG_01369 2.3e-78 yjoA S DinB family
KFDAFNOG_01370 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KFDAFNOG_01371 1e-212 S response regulator aspartate phosphatase
KFDAFNOG_01373 5.2e-37 S YCII-related domain
KFDAFNOG_01374 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KFDAFNOG_01375 1.8e-60 yjqA S Bacterial PH domain
KFDAFNOG_01376 2.1e-111 yjqB S Pfam:DUF867
KFDAFNOG_01377 9.8e-160 ydbD P Catalase
KFDAFNOG_01378 4.3e-109 xkdA E IrrE N-terminal-like domain
KFDAFNOG_01379 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
KFDAFNOG_01381 5e-156 xkdB K sequence-specific DNA binding
KFDAFNOG_01382 9.2e-118 xkdC L Bacterial dnaA protein
KFDAFNOG_01385 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KFDAFNOG_01386 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KFDAFNOG_01387 5.3e-139 xtmA L phage terminase small subunit
KFDAFNOG_01388 1.4e-253 xtmB S phage terminase, large subunit
KFDAFNOG_01389 6e-285 yqbA S portal protein
KFDAFNOG_01390 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KFDAFNOG_01391 1.3e-168 xkdG S Phage capsid family
KFDAFNOG_01392 5.5e-65 yqbG S Protein of unknown function (DUF3199)
KFDAFNOG_01393 8.7e-65 yqbH S Domain of unknown function (DUF3599)
KFDAFNOG_01394 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
KFDAFNOG_01395 1.9e-77 xkdJ
KFDAFNOG_01396 2.5e-256 xkdK S Phage tail sheath C-terminal domain
KFDAFNOG_01397 6.1e-76 xkdM S Phage tail tube protein
KFDAFNOG_01398 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
KFDAFNOG_01399 0.0 xkdO L Transglycosylase SLT domain
KFDAFNOG_01400 4.1e-121 xkdP S Lysin motif
KFDAFNOG_01401 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
KFDAFNOG_01402 2.1e-39 xkdR S Protein of unknown function (DUF2577)
KFDAFNOG_01403 3.1e-69 xkdS S Protein of unknown function (DUF2634)
KFDAFNOG_01404 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KFDAFNOG_01405 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KFDAFNOG_01406 1.5e-40
KFDAFNOG_01407 1e-261
KFDAFNOG_01408 5.4e-53 xkdW S XkdW protein
KFDAFNOG_01409 5.5e-22 xkdX
KFDAFNOG_01410 1.7e-151 xepA
KFDAFNOG_01411 6.2e-39 xhlA S Haemolysin XhlA
KFDAFNOG_01412 9.3e-40 xhlB S SPP1 phage holin
KFDAFNOG_01413 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KFDAFNOG_01414 6.7e-23 spoIISB S Stage II sporulation protein SB
KFDAFNOG_01415 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KFDAFNOG_01416 5.8e-175 pit P phosphate transporter
KFDAFNOG_01417 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KFDAFNOG_01418 4e-240 steT E amino acid
KFDAFNOG_01419 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KFDAFNOG_01420 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFDAFNOG_01421 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KFDAFNOG_01423 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFDAFNOG_01424 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KFDAFNOG_01425 2.5e-152 dppA E D-aminopeptidase
KFDAFNOG_01426 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01427 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFDAFNOG_01428 1.3e-187 dppD P Belongs to the ABC transporter superfamily
KFDAFNOG_01429 0.0 dppE E ABC transporter substrate-binding protein
KFDAFNOG_01431 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KFDAFNOG_01432 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KFDAFNOG_01433 1e-162 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KFDAFNOG_01434 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
KFDAFNOG_01435 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
KFDAFNOG_01436 2e-160 ykgA E Amidinotransferase
KFDAFNOG_01437 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KFDAFNOG_01438 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFDAFNOG_01439 5.5e-09
KFDAFNOG_01440 2.3e-128 ykjA S Protein of unknown function (DUF421)
KFDAFNOG_01441 4.8e-96 ykkA S Protein of unknown function (DUF664)
KFDAFNOG_01442 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KFDAFNOG_01443 3.5e-55 ykkC P Multidrug resistance protein
KFDAFNOG_01444 7e-50 ykkD P Multidrug resistance protein
KFDAFNOG_01445 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KFDAFNOG_01446 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KFDAFNOG_01447 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFDAFNOG_01448 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KFDAFNOG_01449 4.8e-73 ohrR K COG1846 Transcriptional regulators
KFDAFNOG_01450 2.4e-71 ohrB O Organic hydroperoxide resistance protein
KFDAFNOG_01451 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KFDAFNOG_01452 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KFDAFNOG_01453 1.6e-174 isp O Belongs to the peptidase S8 family
KFDAFNOG_01454 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KFDAFNOG_01455 5.3e-136 ykoC P Cobalt transport protein
KFDAFNOG_01456 2.2e-304 P ABC transporter, ATP-binding protein
KFDAFNOG_01457 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KFDAFNOG_01458 1.6e-108 ykoF S YKOF-related Family
KFDAFNOG_01459 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_01460 1.4e-240 ykoH 2.7.13.3 T Histidine kinase
KFDAFNOG_01461 9.9e-110 ykoI S Peptidase propeptide and YPEB domain
KFDAFNOG_01462 8.3e-85 ykoJ S Peptidase propeptide and YPEB domain
KFDAFNOG_01465 2.2e-222 mgtE P Acts as a magnesium transporter
KFDAFNOG_01466 1.4e-53 tnrA K transcriptional
KFDAFNOG_01467 5.9e-18
KFDAFNOG_01468 6.9e-26 ykoL
KFDAFNOG_01469 1.3e-81 mhqR K transcriptional
KFDAFNOG_01470 3.6e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KFDAFNOG_01471 1.4e-98 ykoP G polysaccharide deacetylase
KFDAFNOG_01472 3.5e-154 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KFDAFNOG_01473 0.0 ykoS
KFDAFNOG_01474 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KFDAFNOG_01475 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KFDAFNOG_01476 3.6e-160 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KFDAFNOG_01477 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KFDAFNOG_01478 1.6e-93 ydcR 2.7.7.65 T Diguanylate cyclase
KFDAFNOG_01479 3.5e-109 ykoX S membrane-associated protein
KFDAFNOG_01480 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KFDAFNOG_01481 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_01482 9.1e-116 rsgI S Anti-sigma factor N-terminus
KFDAFNOG_01483 1.9e-26 sspD S small acid-soluble spore protein
KFDAFNOG_01484 1.5e-124 ykrK S Domain of unknown function (DUF1836)
KFDAFNOG_01485 3.5e-155 htpX O Belongs to the peptidase M48B family
KFDAFNOG_01486 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
KFDAFNOG_01487 1.2e-10 ydfR S Protein of unknown function (DUF421)
KFDAFNOG_01488 4.1e-18 ykzE
KFDAFNOG_01489 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KFDAFNOG_01490 0.0 kinE 2.7.13.3 T Histidine kinase
KFDAFNOG_01491 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFDAFNOG_01493 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFDAFNOG_01494 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KFDAFNOG_01495 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KFDAFNOG_01496 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
KFDAFNOG_01497 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KFDAFNOG_01498 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KFDAFNOG_01499 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KFDAFNOG_01500 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFDAFNOG_01501 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
KFDAFNOG_01502 6.4e-09 S Spo0E like sporulation regulatory protein
KFDAFNOG_01503 1.8e-64 eag
KFDAFNOG_01504 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KFDAFNOG_01505 1.3e-75 ykvE K transcriptional
KFDAFNOG_01506 2.5e-125 motB N Flagellar motor protein
KFDAFNOG_01507 1e-137 motA N flagellar motor
KFDAFNOG_01508 0.0 clpE O Belongs to the ClpA ClpB family
KFDAFNOG_01509 2.6e-178 ykvI S membrane
KFDAFNOG_01510 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFDAFNOG_01511 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
KFDAFNOG_01512 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KFDAFNOG_01513 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFDAFNOG_01514 2e-61 ykvN K Transcriptional regulator
KFDAFNOG_01515 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_01516 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
KFDAFNOG_01517 3.5e-35 3.5.1.104 M LysM domain
KFDAFNOG_01518 1.4e-162 G Glycosyl hydrolases family 18
KFDAFNOG_01519 5.6e-46 ykvR S Protein of unknown function (DUF3219)
KFDAFNOG_01520 6e-25 ykvS S protein conserved in bacteria
KFDAFNOG_01521 2.8e-28
KFDAFNOG_01522 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
KFDAFNOG_01523 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_01524 1.6e-88 stoA CO thiol-disulfide
KFDAFNOG_01525 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KFDAFNOG_01526 2.3e-09
KFDAFNOG_01527 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KFDAFNOG_01528 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
KFDAFNOG_01530 2.2e-127 glcT K antiterminator
KFDAFNOG_01531 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_01532 2.1e-39 ptsH G phosphocarrier protein HPr
KFDAFNOG_01533 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFDAFNOG_01534 7.2e-39 splA S Transcriptional regulator
KFDAFNOG_01535 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
KFDAFNOG_01536 4.9e-128 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_01537 1.6e-261 mcpC NT chemotaxis protein
KFDAFNOG_01538 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KFDAFNOG_01539 8e-124 ykwD J protein with SCP PR1 domains
KFDAFNOG_01540 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KFDAFNOG_01541 0.0 pilS 2.7.13.3 T Histidine kinase
KFDAFNOG_01542 8e-224 patA 2.6.1.1 E Aminotransferase
KFDAFNOG_01543 2.2e-15
KFDAFNOG_01544 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KFDAFNOG_01545 1.7e-84 ykyB S YkyB-like protein
KFDAFNOG_01546 1.7e-235 ykuC EGP Major facilitator Superfamily
KFDAFNOG_01547 1.5e-86 ykuD S protein conserved in bacteria
KFDAFNOG_01548 1.6e-165 ykuE S Metallophosphoesterase
KFDAFNOG_01549 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_01550 5.2e-234 ykuI T Diguanylate phosphodiesterase
KFDAFNOG_01551 3.9e-37 ykuJ S protein conserved in bacteria
KFDAFNOG_01552 4.4e-94 ykuK S Ribonuclease H-like
KFDAFNOG_01553 3.9e-27 ykzF S Antirepressor AbbA
KFDAFNOG_01554 1.6e-76 ykuL S CBS domain
KFDAFNOG_01555 3.5e-168 ccpC K Transcriptional regulator
KFDAFNOG_01556 8.5e-84 fld C Flavodoxin domain
KFDAFNOG_01557 3e-175 ykuO
KFDAFNOG_01558 3.9e-78 fld C Flavodoxin
KFDAFNOG_01559 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KFDAFNOG_01560 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KFDAFNOG_01561 9e-37 ykuS S Belongs to the UPF0180 family
KFDAFNOG_01562 8.8e-142 ykuT M Mechanosensitive ion channel
KFDAFNOG_01563 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KFDAFNOG_01564 7e-80 ykuV CO thiol-disulfide
KFDAFNOG_01565 5.8e-95 rok K Repressor of ComK
KFDAFNOG_01566 4.2e-146 yknT
KFDAFNOG_01567 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KFDAFNOG_01568 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KFDAFNOG_01569 8.1e-246 moeA 2.10.1.1 H molybdopterin
KFDAFNOG_01570 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KFDAFNOG_01571 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KFDAFNOG_01572 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFDAFNOG_01573 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KFDAFNOG_01574 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KFDAFNOG_01575 1e-117 yknW S Yip1 domain
KFDAFNOG_01576 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFDAFNOG_01577 2.5e-124 macB V ABC transporter, ATP-binding protein
KFDAFNOG_01578 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KFDAFNOG_01579 3.1e-136 fruR K Transcriptional regulator
KFDAFNOG_01580 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KFDAFNOG_01581 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KFDAFNOG_01582 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KFDAFNOG_01583 8.1e-39 ykoA
KFDAFNOG_01584 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KFDAFNOG_01585 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFDAFNOG_01586 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KFDAFNOG_01587 1.1e-12 S Uncharacterized protein YkpC
KFDAFNOG_01588 7.7e-183 mreB D Rod-share determining protein MreBH
KFDAFNOG_01589 1.5e-43 abrB K of stationary sporulation gene expression
KFDAFNOG_01590 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KFDAFNOG_01591 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KFDAFNOG_01592 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
KFDAFNOG_01593 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KFDAFNOG_01594 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFDAFNOG_01595 8.2e-31 ykzG S Belongs to the UPF0356 family
KFDAFNOG_01596 1.4e-147 ykrA S hydrolases of the HAD superfamily
KFDAFNOG_01597 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KFDAFNOG_01599 2e-115 recN L Putative cell-wall binding lipoprotein
KFDAFNOG_01600 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KFDAFNOG_01601 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KFDAFNOG_01602 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KFDAFNOG_01603 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KFDAFNOG_01604 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KFDAFNOG_01605 3.5e-277 speA 4.1.1.19 E Arginine
KFDAFNOG_01606 1.6e-42 yktA S Belongs to the UPF0223 family
KFDAFNOG_01607 7.1e-118 yktB S Belongs to the UPF0637 family
KFDAFNOG_01608 7.1e-26 ykzI
KFDAFNOG_01609 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
KFDAFNOG_01610 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KFDAFNOG_01611 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KFDAFNOG_01612 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KFDAFNOG_01613 0.0 ylaA
KFDAFNOG_01614 2.7e-42 ylaB
KFDAFNOG_01615 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_01616 1.2e-11 sigC S Putative zinc-finger
KFDAFNOG_01617 1.8e-38 ylaE
KFDAFNOG_01618 8.2e-22 S Family of unknown function (DUF5325)
KFDAFNOG_01619 0.0 typA T GTP-binding protein TypA
KFDAFNOG_01620 4.2e-47 ylaH S YlaH-like protein
KFDAFNOG_01621 2.5e-32 ylaI S protein conserved in bacteria
KFDAFNOG_01622 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KFDAFNOG_01623 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KFDAFNOG_01624 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFDAFNOG_01625 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KFDAFNOG_01626 8.7e-44 ylaN S Belongs to the UPF0358 family
KFDAFNOG_01627 4.5e-214 ftsW D Belongs to the SEDS family
KFDAFNOG_01628 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KFDAFNOG_01629 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KFDAFNOG_01630 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KFDAFNOG_01631 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KFDAFNOG_01632 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFDAFNOG_01633 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KFDAFNOG_01634 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KFDAFNOG_01635 3.4e-166 ctaG S cytochrome c oxidase
KFDAFNOG_01636 7e-62 ylbA S YugN-like family
KFDAFNOG_01637 2.6e-74 ylbB T COG0517 FOG CBS domain
KFDAFNOG_01638 9.6e-200 ylbC S protein with SCP PR1 domains
KFDAFNOG_01639 4.1e-63 ylbD S Putative coat protein
KFDAFNOG_01640 2.5e-36 ylbE S YlbE-like protein
KFDAFNOG_01641 1.8e-75 ylbF S Belongs to the UPF0342 family
KFDAFNOG_01642 3.7e-38 ylbG S UPF0298 protein
KFDAFNOG_01643 1.6e-97 rsmD 2.1.1.171 L Methyltransferase
KFDAFNOG_01644 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFDAFNOG_01645 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
KFDAFNOG_01646 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KFDAFNOG_01647 6.8e-187 ylbL T Belongs to the peptidase S16 family
KFDAFNOG_01648 4e-234 ylbM S Belongs to the UPF0348 family
KFDAFNOG_01650 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KFDAFNOG_01651 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KFDAFNOG_01652 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KFDAFNOG_01653 1.5e-88 ylbP K n-acetyltransferase
KFDAFNOG_01654 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFDAFNOG_01655 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KFDAFNOG_01656 2.9e-78 mraZ K Belongs to the MraZ family
KFDAFNOG_01657 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KFDAFNOG_01658 3.7e-44 ftsL D Essential cell division protein
KFDAFNOG_01659 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KFDAFNOG_01660 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KFDAFNOG_01661 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFDAFNOG_01662 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFDAFNOG_01663 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFDAFNOG_01664 5.7e-186 spoVE D Belongs to the SEDS family
KFDAFNOG_01665 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFDAFNOG_01666 5.3e-167 murB 1.3.1.98 M cell wall formation
KFDAFNOG_01667 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KFDAFNOG_01668 4.1e-103 ylxW S protein conserved in bacteria
KFDAFNOG_01669 2.6e-90 ylxX S protein conserved in bacteria
KFDAFNOG_01670 2.8e-55 sbp S small basic protein
KFDAFNOG_01671 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KFDAFNOG_01672 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFDAFNOG_01673 0.0 bpr O COG1404 Subtilisin-like serine proteases
KFDAFNOG_01674 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KFDAFNOG_01675 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_01676 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_01677 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KFDAFNOG_01678 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
KFDAFNOG_01679 2.4e-37 ylmC S sporulation protein
KFDAFNOG_01680 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KFDAFNOG_01681 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFDAFNOG_01682 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KFDAFNOG_01683 1.6e-39 yggT S membrane
KFDAFNOG_01684 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KFDAFNOG_01685 2.6e-67 divIVA D Cell division initiation protein
KFDAFNOG_01686 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFDAFNOG_01687 1.3e-63 dksA T COG1734 DnaK suppressor protein
KFDAFNOG_01688 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFDAFNOG_01689 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KFDAFNOG_01690 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFDAFNOG_01691 2.6e-231 pyrP F Xanthine uracil
KFDAFNOG_01692 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KFDAFNOG_01693 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KFDAFNOG_01694 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KFDAFNOG_01695 0.0 carB 6.3.5.5 F Belongs to the CarB family
KFDAFNOG_01696 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KFDAFNOG_01697 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KFDAFNOG_01698 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KFDAFNOG_01699 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFDAFNOG_01701 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KFDAFNOG_01702 1.2e-178 cysP P phosphate transporter
KFDAFNOG_01703 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KFDAFNOG_01704 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KFDAFNOG_01705 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KFDAFNOG_01706 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KFDAFNOG_01707 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KFDAFNOG_01708 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KFDAFNOG_01709 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KFDAFNOG_01710 3.1e-156 yloC S stress-induced protein
KFDAFNOG_01711 1.5e-40 ylzA S Belongs to the UPF0296 family
KFDAFNOG_01712 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KFDAFNOG_01713 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KFDAFNOG_01714 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFDAFNOG_01715 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFDAFNOG_01716 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KFDAFNOG_01717 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFDAFNOG_01718 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFDAFNOG_01719 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KFDAFNOG_01720 1.6e-140 stp 3.1.3.16 T phosphatase
KFDAFNOG_01721 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KFDAFNOG_01722 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KFDAFNOG_01723 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KFDAFNOG_01724 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
KFDAFNOG_01725 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KFDAFNOG_01726 5.5e-59 asp S protein conserved in bacteria
KFDAFNOG_01727 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
KFDAFNOG_01728 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KFDAFNOG_01729 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
KFDAFNOG_01730 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFDAFNOG_01731 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KFDAFNOG_01732 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KFDAFNOG_01733 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KFDAFNOG_01734 1.1e-127 IQ reductase
KFDAFNOG_01735 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFDAFNOG_01736 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KFDAFNOG_01737 0.0 smc D Required for chromosome condensation and partitioning
KFDAFNOG_01738 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KFDAFNOG_01739 3.5e-85
KFDAFNOG_01740 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KFDAFNOG_01741 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFDAFNOG_01742 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KFDAFNOG_01743 4.5e-36 ylqC S Belongs to the UPF0109 family
KFDAFNOG_01744 6.3e-61 ylqD S YlqD protein
KFDAFNOG_01745 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFDAFNOG_01746 7.8e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KFDAFNOG_01747 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KFDAFNOG_01748 2.3e-156 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KFDAFNOG_01749 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFDAFNOG_01750 4.3e-287 ylqG
KFDAFNOG_01751 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KFDAFNOG_01752 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KFDAFNOG_01753 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFDAFNOG_01754 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KFDAFNOG_01755 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFDAFNOG_01756 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KFDAFNOG_01757 2.5e-169 xerC L tyrosine recombinase XerC
KFDAFNOG_01758 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KFDAFNOG_01759 4.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KFDAFNOG_01760 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KFDAFNOG_01761 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KFDAFNOG_01762 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KFDAFNOG_01763 1.9e-31 fliE N Flagellar hook-basal body
KFDAFNOG_01764 1.6e-254 fliF N The M ring may be actively involved in energy transduction
KFDAFNOG_01765 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KFDAFNOG_01766 5.7e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KFDAFNOG_01767 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KFDAFNOG_01768 1.5e-69 fliJ N Flagellar biosynthesis chaperone
KFDAFNOG_01769 7.7e-37 ylxF S MgtE intracellular N domain
KFDAFNOG_01770 5.1e-220 fliK N Flagellar hook-length control protein
KFDAFNOG_01771 2.3e-72 flgD N Flagellar basal body rod modification protein
KFDAFNOG_01772 8.2e-140 flgG N Flagellar basal body rod
KFDAFNOG_01773 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KFDAFNOG_01774 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KFDAFNOG_01775 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KFDAFNOG_01776 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KFDAFNOG_01777 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
KFDAFNOG_01778 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KFDAFNOG_01779 2.2e-36 fliQ N Role in flagellar biosynthesis
KFDAFNOG_01780 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KFDAFNOG_01781 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFDAFNOG_01782 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KFDAFNOG_01783 1.5e-200 flhF N Flagellar biosynthesis regulator FlhF
KFDAFNOG_01784 2.2e-157 flhG D Belongs to the ParA family
KFDAFNOG_01785 4.9e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KFDAFNOG_01786 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KFDAFNOG_01787 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KFDAFNOG_01788 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KFDAFNOG_01789 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KFDAFNOG_01790 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_01791 3.1e-76 ylxL
KFDAFNOG_01792 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KFDAFNOG_01793 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFDAFNOG_01794 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KFDAFNOG_01795 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KFDAFNOG_01796 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFDAFNOG_01797 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KFDAFNOG_01798 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KFDAFNOG_01799 7.7e-233 rasP M zinc metalloprotease
KFDAFNOG_01800 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KFDAFNOG_01801 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFDAFNOG_01802 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KFDAFNOG_01803 1.1e-203 nusA K Participates in both transcription termination and antitermination
KFDAFNOG_01804 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KFDAFNOG_01805 3.1e-47 ylxQ J ribosomal protein
KFDAFNOG_01806 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFDAFNOG_01807 3e-44 ylxP S protein conserved in bacteria
KFDAFNOG_01808 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFDAFNOG_01809 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFDAFNOG_01810 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KFDAFNOG_01811 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFDAFNOG_01812 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KFDAFNOG_01813 6.1e-182 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KFDAFNOG_01814 4.4e-233 pepR S Belongs to the peptidase M16 family
KFDAFNOG_01815 2.6e-42 ymxH S YlmC YmxH family
KFDAFNOG_01816 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KFDAFNOG_01817 6.3e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KFDAFNOG_01818 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFDAFNOG_01819 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KFDAFNOG_01820 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFDAFNOG_01821 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KFDAFNOG_01822 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KFDAFNOG_01823 4.4e-32 S YlzJ-like protein
KFDAFNOG_01824 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KFDAFNOG_01825 1.4e-133 ymfC K Transcriptional regulator
KFDAFNOG_01826 3.8e-205 ymfD EGP Major facilitator Superfamily
KFDAFNOG_01827 2e-233 ymfF S Peptidase M16
KFDAFNOG_01828 1.4e-242 ymfH S zinc protease
KFDAFNOG_01829 7.8e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KFDAFNOG_01830 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KFDAFNOG_01831 2.7e-143 ymfK S Protein of unknown function (DUF3388)
KFDAFNOG_01832 7.3e-116 ymfM S protein conserved in bacteria
KFDAFNOG_01833 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFDAFNOG_01834 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
KFDAFNOG_01835 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFDAFNOG_01836 1e-215 pbpX V Beta-lactamase
KFDAFNOG_01837 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KFDAFNOG_01838 1.9e-152 ymdB S protein conserved in bacteria
KFDAFNOG_01839 1.2e-36 spoVS S Stage V sporulation protein S
KFDAFNOG_01840 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KFDAFNOG_01841 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KFDAFNOG_01842 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFDAFNOG_01843 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KFDAFNOG_01844 2.2e-88 cotE S Spore coat protein
KFDAFNOG_01845 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFDAFNOG_01846 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFDAFNOG_01847 2.3e-70 S Regulatory protein YrvL
KFDAFNOG_01849 1.2e-97 ymcC S Membrane
KFDAFNOG_01850 4.4e-109 pksA K Transcriptional regulator
KFDAFNOG_01851 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KFDAFNOG_01852 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KFDAFNOG_01854 2.4e-186 pksD Q Acyl transferase domain
KFDAFNOG_01855 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KFDAFNOG_01856 1.4e-37 acpK IQ Phosphopantetheine attachment site
KFDAFNOG_01857 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KFDAFNOG_01858 1.3e-245 pksG 2.3.3.10 I synthase
KFDAFNOG_01859 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
KFDAFNOG_01860 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KFDAFNOG_01861 0.0 rhiB IQ polyketide synthase
KFDAFNOG_01862 0.0 pfaA Q Polyketide synthase of type I
KFDAFNOG_01863 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KFDAFNOG_01864 0.0 dhbF IQ polyketide synthase
KFDAFNOG_01865 0.0 pks13 HQ Beta-ketoacyl synthase
KFDAFNOG_01866 6.3e-232 cypA C Cytochrome P450
KFDAFNOG_01867 2e-61 ymzB
KFDAFNOG_01868 8.1e-162 ymaE S Metallo-beta-lactamase superfamily
KFDAFNOG_01869 8.6e-251 aprX O Belongs to the peptidase S8 family
KFDAFNOG_01870 1.9e-07 K Transcriptional regulator
KFDAFNOG_01871 2.1e-126 ymaC S Replication protein
KFDAFNOG_01872 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
KFDAFNOG_01873 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KFDAFNOG_01874 5.4e-50 ebrA P Small Multidrug Resistance protein
KFDAFNOG_01876 2.1e-46 ymaF S YmaF family
KFDAFNOG_01877 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFDAFNOG_01878 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KFDAFNOG_01879 8.2e-23
KFDAFNOG_01880 4.5e-22 ymzA
KFDAFNOG_01881 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KFDAFNOG_01882 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFDAFNOG_01883 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFDAFNOG_01884 2e-109 ymaB
KFDAFNOG_01885 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KFDAFNOG_01886 1.7e-176 spoVK O stage V sporulation protein K
KFDAFNOG_01887 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFDAFNOG_01888 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KFDAFNOG_01889 1.1e-68 glnR K transcriptional
KFDAFNOG_01890 7e-261 glnA 6.3.1.2 E glutamine synthetase
KFDAFNOG_01891 1.1e-09
KFDAFNOG_01892 1.6e-31
KFDAFNOG_01893 2.1e-16
KFDAFNOG_01894 8.9e-90 G SMI1-KNR4 cell-wall
KFDAFNOG_01895 3.1e-113 ynaC
KFDAFNOG_01896 4.1e-11 S Protein of unknown function (DUF1433)
KFDAFNOG_01897 2e-97 ynaD J Acetyltransferase (GNAT) domain
KFDAFNOG_01898 4.1e-73 S CAAX protease self-immunity
KFDAFNOG_01899 4.7e-08 S Uncharacterised protein family (UPF0715)
KFDAFNOG_01900 5.5e-20 K Cro/C1-type HTH DNA-binding domain
KFDAFNOG_01901 2.1e-117 ynaE S Domain of unknown function (DUF3885)
KFDAFNOG_01902 8.6e-15 ynaF
KFDAFNOG_01904 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
KFDAFNOG_01905 7.9e-255 xynT G MFS/sugar transport protein
KFDAFNOG_01906 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KFDAFNOG_01907 6.8e-212 xylR GK ROK family
KFDAFNOG_01908 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KFDAFNOG_01909 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KFDAFNOG_01910 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
KFDAFNOG_01911 1.4e-254 iolT EGP Major facilitator Superfamily
KFDAFNOG_01912 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFDAFNOG_01914 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KFDAFNOG_01915 5.2e-15
KFDAFNOG_01918 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFDAFNOG_01920 8.9e-128 S Domain of unknown function, YrpD
KFDAFNOG_01923 7.9e-25 tatA U protein secretion
KFDAFNOG_01924 1.8e-71
KFDAFNOG_01925 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KFDAFNOG_01928 2.8e-52 gerAA EG Spore germination protein
KFDAFNOG_01929 4.8e-144 gerAA EG Spore germination protein
KFDAFNOG_01930 3.4e-88 gerLC S Spore germination protein
KFDAFNOG_01931 7.7e-154 yndG S DoxX-like family
KFDAFNOG_01932 2.6e-117 yndH S Domain of unknown function (DUF4166)
KFDAFNOG_01933 0.0 yndJ S YndJ-like protein
KFDAFNOG_01935 8.6e-139 yndL S Replication protein
KFDAFNOG_01936 5.8e-74 yndM S Protein of unknown function (DUF2512)
KFDAFNOG_01937 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KFDAFNOG_01938 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFDAFNOG_01939 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KFDAFNOG_01940 5e-111 yneB L resolvase
KFDAFNOG_01941 1.3e-32 ynzC S UPF0291 protein
KFDAFNOG_01942 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFDAFNOG_01943 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KFDAFNOG_01944 1.8e-28 yneF S UPF0154 protein
KFDAFNOG_01945 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KFDAFNOG_01946 7.1e-127 ccdA O cytochrome c biogenesis protein
KFDAFNOG_01947 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KFDAFNOG_01948 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KFDAFNOG_01949 4.2e-74 yneK S Protein of unknown function (DUF2621)
KFDAFNOG_01950 1.2e-64 hspX O Spore coat protein
KFDAFNOG_01951 3.9e-19 sspP S Belongs to the SspP family
KFDAFNOG_01952 2.2e-14 sspO S Belongs to the SspO family
KFDAFNOG_01953 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KFDAFNOG_01954 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFDAFNOG_01956 3.1e-08 sspN S Small acid-soluble spore protein N family
KFDAFNOG_01957 3.9e-35 tlp S Belongs to the Tlp family
KFDAFNOG_01958 2e-73 yneP S Thioesterase-like superfamily
KFDAFNOG_01959 1.7e-53 yneQ
KFDAFNOG_01960 4.1e-49 yneR S Belongs to the HesB IscA family
KFDAFNOG_01961 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KFDAFNOG_01962 8.6e-69 yccU S CoA-binding protein
KFDAFNOG_01963 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KFDAFNOG_01964 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KFDAFNOG_01965 2.3e-12
KFDAFNOG_01966 1.3e-57 ynfC
KFDAFNOG_01967 1.8e-251 agcS E Sodium alanine symporter
KFDAFNOG_01968 9.9e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KFDAFNOG_01970 1.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KFDAFNOG_01971 7.8e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KFDAFNOG_01972 1.6e-79 yngA S membrane
KFDAFNOG_01973 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KFDAFNOG_01974 5.5e-104 yngC S membrane-associated protein
KFDAFNOG_01975 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
KFDAFNOG_01976 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KFDAFNOG_01977 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KFDAFNOG_01978 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KFDAFNOG_01979 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KFDAFNOG_01980 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KFDAFNOG_01981 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KFDAFNOG_01982 1.2e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KFDAFNOG_01983 5e-303 yngK T Glycosyl hydrolase-like 10
KFDAFNOG_01984 4e-63 yngL S Protein of unknown function (DUF1360)
KFDAFNOG_01985 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KFDAFNOG_01986 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_01987 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_01988 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_01989 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_01990 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KFDAFNOG_01991 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
KFDAFNOG_01992 2.3e-246 yoeA V MATE efflux family protein
KFDAFNOG_01993 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
KFDAFNOG_01995 2.2e-96 L Integrase
KFDAFNOG_01996 3e-34 yoeD G Helix-turn-helix domain
KFDAFNOG_01997 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KFDAFNOG_01998 2.3e-156 gltR1 K Transcriptional regulator
KFDAFNOG_01999 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KFDAFNOG_02000 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KFDAFNOG_02001 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KFDAFNOG_02002 3.9e-154 gltC K Transcriptional regulator
KFDAFNOG_02003 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KFDAFNOG_02004 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFDAFNOG_02005 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KFDAFNOG_02006 7.7e-121 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_02007 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
KFDAFNOG_02008 2.5e-130 yoxB
KFDAFNOG_02009 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KFDAFNOG_02010 3.8e-126 V ABC-2 family transporter protein
KFDAFNOG_02011 2.9e-94 V ABC-2 family transporter protein
KFDAFNOG_02012 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
KFDAFNOG_02013 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_02014 1.2e-233 yoaB EGP Major facilitator Superfamily
KFDAFNOG_02015 1.5e-277 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KFDAFNOG_02016 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFDAFNOG_02017 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFDAFNOG_02018 6.6e-32 yoaF
KFDAFNOG_02019 3e-172 iolT EGP Major facilitator Superfamily
KFDAFNOG_02020 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
KFDAFNOG_02021 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
KFDAFNOG_02022 3.3e-90 purR K Transcriptional regulator
KFDAFNOG_02023 2.2e-07
KFDAFNOG_02024 7e-14
KFDAFNOG_02025 1.5e-38 S Protein of unknown function (DUF4025)
KFDAFNOG_02026 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
KFDAFNOG_02027 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KFDAFNOG_02028 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KFDAFNOG_02029 2.3e-111 yoaK S Membrane
KFDAFNOG_02030 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KFDAFNOG_02031 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
KFDAFNOG_02033 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
KFDAFNOG_02036 7.3e-86
KFDAFNOG_02037 9.3e-172 yoaR V vancomycin resistance protein
KFDAFNOG_02038 2.8e-74 yoaS S Protein of unknown function (DUF2975)
KFDAFNOG_02039 4.4e-30 yozG K Transcriptional regulator
KFDAFNOG_02040 5.3e-147 yoaT S Protein of unknown function (DUF817)
KFDAFNOG_02041 8.6e-159 yoaU K LysR substrate binding domain
KFDAFNOG_02042 1.5e-158 yijE EG EamA-like transporter family
KFDAFNOG_02043 1.8e-77 yoaW
KFDAFNOG_02044 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KFDAFNOG_02045 3.8e-165 bla 3.5.2.6 V beta-lactamase
KFDAFNOG_02048 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KFDAFNOG_02049 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KFDAFNOG_02051 1.7e-40
KFDAFNOG_02053 2.7e-176 T PhoQ Sensor
KFDAFNOG_02054 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
KFDAFNOG_02055 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KFDAFNOG_02056 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KFDAFNOG_02058 2.8e-84 S SMI1-KNR4 cell-wall
KFDAFNOG_02059 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KFDAFNOG_02060 9.1e-101 yokH G SMI1 / KNR4 family
KFDAFNOG_02061 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KFDAFNOG_02062 0.0 yobO M Pectate lyase superfamily protein
KFDAFNOG_02063 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KFDAFNOG_02064 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
KFDAFNOG_02065 5.3e-141 yobR 2.3.1.1 J FR47-like protein
KFDAFNOG_02066 1.3e-97 yobS K Transcriptional regulator
KFDAFNOG_02067 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KFDAFNOG_02068 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
KFDAFNOG_02069 6.2e-171 yobV K WYL domain
KFDAFNOG_02070 1.8e-90 yobW
KFDAFNOG_02071 1e-51 czrA K transcriptional
KFDAFNOG_02072 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KFDAFNOG_02073 1.5e-92 yozB S membrane
KFDAFNOG_02074 1.3e-142
KFDAFNOG_02075 1.2e-93 yocC
KFDAFNOG_02076 1.5e-188 yocD 3.4.17.13 V peptidase S66
KFDAFNOG_02077 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KFDAFNOG_02078 1.7e-196 desK 2.7.13.3 T Histidine kinase
KFDAFNOG_02079 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_02080 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KFDAFNOG_02081 0.0 recQ 3.6.4.12 L DNA helicase
KFDAFNOG_02082 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KFDAFNOG_02083 3.3e-83 dksA T general stress protein
KFDAFNOG_02084 6.4e-54 yocL
KFDAFNOG_02085 6.6e-34
KFDAFNOG_02086 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KFDAFNOG_02087 1.1e-40 yozN
KFDAFNOG_02088 1.9e-36 yocN
KFDAFNOG_02089 4.2e-56 yozO S Bacterial PH domain
KFDAFNOG_02090 2.7e-31 yozC
KFDAFNOG_02091 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KFDAFNOG_02092 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KFDAFNOG_02093 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
KFDAFNOG_02094 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KFDAFNOG_02095 8.6e-168 yocS S -transporter
KFDAFNOG_02096 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KFDAFNOG_02097 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KFDAFNOG_02098 0.0 yojO P Von Willebrand factor
KFDAFNOG_02099 5.5e-161 yojN S ATPase family associated with various cellular activities (AAA)
KFDAFNOG_02100 1.7e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFDAFNOG_02101 3.9e-197 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KFDAFNOG_02102 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KFDAFNOG_02103 4.1e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KFDAFNOG_02105 6.1e-244 norM V Multidrug efflux pump
KFDAFNOG_02106 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KFDAFNOG_02107 2.1e-125 yojG S deacetylase
KFDAFNOG_02108 2.2e-60 yojF S Protein of unknown function (DUF1806)
KFDAFNOG_02109 2.5e-43
KFDAFNOG_02110 2.8e-160 rarD S -transporter
KFDAFNOG_02111 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
KFDAFNOG_02112 3.4e-09
KFDAFNOG_02113 1.2e-207 gntP EG COG2610 H gluconate symporter and related permeases
KFDAFNOG_02114 4.7e-64 yodA S tautomerase
KFDAFNOG_02115 4.4e-55 yodB K transcriptional
KFDAFNOG_02116 4.8e-108 yodC C nitroreductase
KFDAFNOG_02117 3.6e-111 mhqD S Carboxylesterase
KFDAFNOG_02118 1.4e-172 yodE E COG0346 Lactoylglutathione lyase and related lyases
KFDAFNOG_02119 1.8e-27 S Protein of unknown function (DUF3311)
KFDAFNOG_02120 6e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFDAFNOG_02121 1.8e-251 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KFDAFNOG_02122 6.3e-128 yodH Q Methyltransferase
KFDAFNOG_02123 1.5e-23 yodI
KFDAFNOG_02124 3.7e-135 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KFDAFNOG_02125 9.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KFDAFNOG_02126 5.3e-09
KFDAFNOG_02127 3.6e-54 yodL S YodL-like
KFDAFNOG_02128 1.6e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KFDAFNOG_02129 6.3e-24 yozD S YozD-like protein
KFDAFNOG_02131 1.6e-123 yodN
KFDAFNOG_02132 1.4e-36 yozE S Belongs to the UPF0346 family
KFDAFNOG_02133 2.9e-47 yokU S YokU-like protein, putative antitoxin
KFDAFNOG_02134 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KFDAFNOG_02135 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KFDAFNOG_02136 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
KFDAFNOG_02137 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KFDAFNOG_02138 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFDAFNOG_02139 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KFDAFNOG_02141 8.3e-145 yiiD K acetyltransferase
KFDAFNOG_02142 1e-256 cgeD M maturation of the outermost layer of the spore
KFDAFNOG_02143 3.5e-38 cgeC
KFDAFNOG_02144 1.2e-65 cgeA
KFDAFNOG_02145 2e-185 cgeB S Spore maturation protein
KFDAFNOG_02146 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KFDAFNOG_02147 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
KFDAFNOG_02148 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KFDAFNOG_02149 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFDAFNOG_02150 1.6e-70 ypoP K transcriptional
KFDAFNOG_02151 3.8e-222 mepA V MATE efflux family protein
KFDAFNOG_02152 5.5e-29 ypmT S Uncharacterized ympT
KFDAFNOG_02153 1.1e-98 ypmS S protein conserved in bacteria
KFDAFNOG_02154 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KFDAFNOG_02155 1.2e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KFDAFNOG_02156 8.9e-40 ypmP S Protein of unknown function (DUF2535)
KFDAFNOG_02157 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFDAFNOG_02158 1.8e-181 pspF K Transcriptional regulator
KFDAFNOG_02159 4.2e-110 hlyIII S protein, Hemolysin III
KFDAFNOG_02160 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KFDAFNOG_02161 1.1e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KFDAFNOG_02162 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFDAFNOG_02163 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KFDAFNOG_02164 7.8e-114 ypjP S YpjP-like protein
KFDAFNOG_02165 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KFDAFNOG_02166 1.7e-75 yphP S Belongs to the UPF0403 family
KFDAFNOG_02167 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KFDAFNOG_02168 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
KFDAFNOG_02169 5.4e-107 ypgQ S phosphohydrolase
KFDAFNOG_02170 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KFDAFNOG_02171 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFDAFNOG_02172 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KFDAFNOG_02173 7.9e-31 cspD K Cold-shock protein
KFDAFNOG_02174 3.8e-16 degR
KFDAFNOG_02175 1.8e-30 S Protein of unknown function (DUF2564)
KFDAFNOG_02176 2.6e-27 ypeQ S Zinc-finger
KFDAFNOG_02177 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KFDAFNOG_02178 7.4e-121 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KFDAFNOG_02179 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
KFDAFNOG_02181 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KFDAFNOG_02182 2e-07
KFDAFNOG_02183 8.5e-38 ypbS S Protein of unknown function (DUF2533)
KFDAFNOG_02184 0.0 ypbR S Dynamin family
KFDAFNOG_02186 7.4e-86 ypbQ S protein conserved in bacteria
KFDAFNOG_02187 8.2e-207 bcsA Q Naringenin-chalcone synthase
KFDAFNOG_02188 3.8e-227 pbuX F xanthine
KFDAFNOG_02189 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KFDAFNOG_02190 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KFDAFNOG_02191 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KFDAFNOG_02192 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KFDAFNOG_02193 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KFDAFNOG_02194 7.4e-186 ptxS K transcriptional
KFDAFNOG_02195 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KFDAFNOG_02196 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_02197 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KFDAFNOG_02199 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KFDAFNOG_02200 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KFDAFNOG_02201 8.2e-91 ypsA S Belongs to the UPF0398 family
KFDAFNOG_02202 2.5e-236 yprB L RNase_H superfamily
KFDAFNOG_02203 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KFDAFNOG_02204 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KFDAFNOG_02205 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
KFDAFNOG_02206 6.6e-47 yppG S YppG-like protein
KFDAFNOG_02208 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
KFDAFNOG_02211 5.4e-186 yppC S Protein of unknown function (DUF2515)
KFDAFNOG_02212 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KFDAFNOG_02213 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KFDAFNOG_02214 1.8e-92 ypoC
KFDAFNOG_02215 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFDAFNOG_02216 1.3e-128 dnaD L DNA replication protein DnaD
KFDAFNOG_02217 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KFDAFNOG_02218 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KFDAFNOG_02219 4.9e-79 ypmB S protein conserved in bacteria
KFDAFNOG_02220 1.9e-22 ypmA S Protein of unknown function (DUF4264)
KFDAFNOG_02221 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KFDAFNOG_02222 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFDAFNOG_02223 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFDAFNOG_02224 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KFDAFNOG_02225 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KFDAFNOG_02226 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KFDAFNOG_02227 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KFDAFNOG_02228 1.7e-128 bshB1 S proteins, LmbE homologs
KFDAFNOG_02229 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KFDAFNOG_02230 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KFDAFNOG_02231 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KFDAFNOG_02232 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KFDAFNOG_02233 1e-142 ypjB S sporulation protein
KFDAFNOG_02234 7.6e-98 ypjA S membrane
KFDAFNOG_02235 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KFDAFNOG_02236 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KFDAFNOG_02237 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KFDAFNOG_02238 1.9e-77 ypiF S Protein of unknown function (DUF2487)
KFDAFNOG_02239 2.8e-99 ypiB S Belongs to the UPF0302 family
KFDAFNOG_02240 2.7e-233 S COG0457 FOG TPR repeat
KFDAFNOG_02241 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KFDAFNOG_02242 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KFDAFNOG_02243 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFDAFNOG_02244 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KFDAFNOG_02245 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KFDAFNOG_02246 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KFDAFNOG_02247 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KFDAFNOG_02248 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFDAFNOG_02249 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFDAFNOG_02250 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KFDAFNOG_02251 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFDAFNOG_02252 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFDAFNOG_02253 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KFDAFNOG_02254 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KFDAFNOG_02255 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KFDAFNOG_02256 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KFDAFNOG_02257 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KFDAFNOG_02258 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KFDAFNOG_02259 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KFDAFNOG_02260 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KFDAFNOG_02261 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KFDAFNOG_02262 3.9e-136 yphF
KFDAFNOG_02263 1.6e-18 yphE S Protein of unknown function (DUF2768)
KFDAFNOG_02264 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KFDAFNOG_02265 2e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KFDAFNOG_02266 7.9e-28 ypzH
KFDAFNOG_02267 2.5e-161 seaA S YIEGIA protein
KFDAFNOG_02268 1.3e-102 yphA
KFDAFNOG_02269 1e-07 S YpzI-like protein
KFDAFNOG_02270 2.2e-185 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KFDAFNOG_02271 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KFDAFNOG_02272 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KFDAFNOG_02273 1.8e-23 S Family of unknown function (DUF5359)
KFDAFNOG_02274 6.6e-111 ypfA M Flagellar protein YcgR
KFDAFNOG_02275 1.9e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KFDAFNOG_02276 9.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KFDAFNOG_02277 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
KFDAFNOG_02278 4.8e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KFDAFNOG_02279 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KFDAFNOG_02280 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KFDAFNOG_02281 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
KFDAFNOG_02282 2.8e-81 ypbF S Protein of unknown function (DUF2663)
KFDAFNOG_02283 4.6e-81 ypbE M Lysin motif
KFDAFNOG_02284 2.2e-100 ypbD S metal-dependent membrane protease
KFDAFNOG_02285 3.2e-286 recQ 3.6.4.12 L DNA helicase
KFDAFNOG_02286 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
KFDAFNOG_02287 4.7e-41 fer C Ferredoxin
KFDAFNOG_02288 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KFDAFNOG_02289 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFDAFNOG_02290 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KFDAFNOG_02291 7.3e-195 rsiX
KFDAFNOG_02292 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_02293 0.0 resE 2.7.13.3 T Histidine kinase
KFDAFNOG_02294 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_02295 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KFDAFNOG_02296 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KFDAFNOG_02297 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KFDAFNOG_02298 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KFDAFNOG_02299 1.9e-87 spmB S Spore maturation protein
KFDAFNOG_02300 3.5e-103 spmA S Spore maturation protein
KFDAFNOG_02301 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KFDAFNOG_02302 7.6e-97 ypuI S Protein of unknown function (DUF3907)
KFDAFNOG_02303 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFDAFNOG_02304 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFDAFNOG_02305 1.4e-92 ypuF S Domain of unknown function (DUF309)
KFDAFNOG_02306 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_02307 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KFDAFNOG_02308 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFDAFNOG_02309 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
KFDAFNOG_02310 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFDAFNOG_02311 7.8e-55 ypuD
KFDAFNOG_02312 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KFDAFNOG_02313 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KFDAFNOG_02314 3.4e-13 S PAP2 superfamily
KFDAFNOG_02316 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
KFDAFNOG_02318 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFDAFNOG_02319 7.3e-07
KFDAFNOG_02323 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFDAFNOG_02324 3.6e-149 ypuA S Secreted protein
KFDAFNOG_02325 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KFDAFNOG_02326 1.4e-273 spoVAF EG Stage V sporulation protein AF
KFDAFNOG_02327 1.4e-110 spoVAEA S stage V sporulation protein
KFDAFNOG_02328 2.2e-57 spoVAEB S stage V sporulation protein
KFDAFNOG_02329 9e-192 spoVAD I Stage V sporulation protein AD
KFDAFNOG_02330 2.3e-78 spoVAC S stage V sporulation protein AC
KFDAFNOG_02331 1e-67 spoVAB S Stage V sporulation protein AB
KFDAFNOG_02332 7.4e-112 spoVAA S Stage V sporulation protein AA
KFDAFNOG_02333 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_02334 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KFDAFNOG_02335 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KFDAFNOG_02336 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KFDAFNOG_02337 3.8e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KFDAFNOG_02338 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KFDAFNOG_02339 2.6e-166 xerD L recombinase XerD
KFDAFNOG_02340 3.7e-37 S Protein of unknown function (DUF4227)
KFDAFNOG_02341 2.4e-80 fur P Belongs to the Fur family
KFDAFNOG_02342 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KFDAFNOG_02343 5.5e-30 yqkK
KFDAFNOG_02344 5.5e-242 mleA 1.1.1.38 C malic enzyme
KFDAFNOG_02345 2.7e-234 mleN C Na H antiporter
KFDAFNOG_02346 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KFDAFNOG_02347 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
KFDAFNOG_02348 4.5e-58 ansR K Transcriptional regulator
KFDAFNOG_02349 3e-223 yqxK 3.6.4.12 L DNA helicase
KFDAFNOG_02350 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KFDAFNOG_02352 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KFDAFNOG_02353 4e-14 yqkE S Protein of unknown function (DUF3886)
KFDAFNOG_02354 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KFDAFNOG_02355 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KFDAFNOG_02356 2.8e-54 yqkB S Belongs to the HesB IscA family
KFDAFNOG_02357 1.2e-194 yqkA K GrpB protein
KFDAFNOG_02358 7.5e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KFDAFNOG_02359 3.6e-87 yqjY K acetyltransferase
KFDAFNOG_02360 6.3e-49 S YolD-like protein
KFDAFNOG_02361 1.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFDAFNOG_02363 4.9e-224 yqjV G Major Facilitator Superfamily
KFDAFNOG_02365 2.1e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_02366 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
KFDAFNOG_02367 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KFDAFNOG_02368 4.6e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_02369 1.4e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KFDAFNOG_02370 5.6e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFDAFNOG_02371 0.0 rocB E arginine degradation protein
KFDAFNOG_02372 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KFDAFNOG_02373 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KFDAFNOG_02374 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KFDAFNOG_02375 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFDAFNOG_02376 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFDAFNOG_02377 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFDAFNOG_02378 4.5e-24 yqzJ
KFDAFNOG_02379 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KFDAFNOG_02380 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
KFDAFNOG_02381 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KFDAFNOG_02382 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KFDAFNOG_02383 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KFDAFNOG_02385 1.4e-98 yqjB S protein conserved in bacteria
KFDAFNOG_02386 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
KFDAFNOG_02387 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KFDAFNOG_02388 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
KFDAFNOG_02389 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
KFDAFNOG_02390 9.3e-77 yqiW S Belongs to the UPF0403 family
KFDAFNOG_02391 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KFDAFNOG_02392 5.1e-207 norA EGP Major facilitator Superfamily
KFDAFNOG_02393 6.4e-151 bmrR K helix_turn_helix, mercury resistance
KFDAFNOG_02394 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KFDAFNOG_02395 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KFDAFNOG_02396 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KFDAFNOG_02397 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KFDAFNOG_02398 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KFDAFNOG_02399 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KFDAFNOG_02400 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KFDAFNOG_02401 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KFDAFNOG_02402 4e-34 yqzF S Protein of unknown function (DUF2627)
KFDAFNOG_02403 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KFDAFNOG_02404 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KFDAFNOG_02405 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KFDAFNOG_02406 8.8e-212 mmgC I acyl-CoA dehydrogenase
KFDAFNOG_02407 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
KFDAFNOG_02408 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
KFDAFNOG_02409 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KFDAFNOG_02410 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KFDAFNOG_02411 5.9e-27
KFDAFNOG_02412 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KFDAFNOG_02414 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KFDAFNOG_02415 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KFDAFNOG_02416 0.0 recN L May be involved in recombinational repair of damaged DNA
KFDAFNOG_02417 1.7e-78 argR K Regulates arginine biosynthesis genes
KFDAFNOG_02418 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KFDAFNOG_02419 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFDAFNOG_02420 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KFDAFNOG_02421 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KFDAFNOG_02422 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KFDAFNOG_02423 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFDAFNOG_02424 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFDAFNOG_02425 2.1e-67 yqhY S protein conserved in bacteria
KFDAFNOG_02426 3.4e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KFDAFNOG_02427 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KFDAFNOG_02428 9.9e-91 spoIIIAH S SpoIIIAH-like protein
KFDAFNOG_02429 2.2e-109 spoIIIAG S stage III sporulation protein AG
KFDAFNOG_02430 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KFDAFNOG_02431 1.3e-197 spoIIIAE S stage III sporulation protein AE
KFDAFNOG_02432 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KFDAFNOG_02433 7.6e-29 spoIIIAC S stage III sporulation protein AC
KFDAFNOG_02434 1.1e-84 spoIIIAB S Stage III sporulation protein
KFDAFNOG_02435 3e-170 spoIIIAA S stage III sporulation protein AA
KFDAFNOG_02436 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KFDAFNOG_02437 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFDAFNOG_02438 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KFDAFNOG_02439 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KFDAFNOG_02440 2.3e-93 yqhR S Conserved membrane protein YqhR
KFDAFNOG_02441 4.7e-174 yqhQ S Protein of unknown function (DUF1385)
KFDAFNOG_02442 2.2e-61 yqhP
KFDAFNOG_02443 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
KFDAFNOG_02444 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KFDAFNOG_02445 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KFDAFNOG_02446 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KFDAFNOG_02447 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFDAFNOG_02448 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFDAFNOG_02449 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KFDAFNOG_02450 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KFDAFNOG_02451 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KFDAFNOG_02452 1.2e-24 sinI S Anti-repressor SinI
KFDAFNOG_02453 1e-54 sinR K transcriptional
KFDAFNOG_02454 2.5e-141 tasA S Cell division protein FtsN
KFDAFNOG_02455 2.5e-58 sipW 3.4.21.89 U Signal peptidase
KFDAFNOG_02456 2.8e-113 yqxM
KFDAFNOG_02457 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KFDAFNOG_02458 4.4e-25 yqzE S YqzE-like protein
KFDAFNOG_02459 8.8e-44 S ComG operon protein 7
KFDAFNOG_02460 1.7e-34 comGF U Putative Competence protein ComGF
KFDAFNOG_02461 2e-58 comGE
KFDAFNOG_02462 6.3e-70 gspH NU protein transport across the cell outer membrane
KFDAFNOG_02463 6.8e-47 comGC U Required for transformation and DNA binding
KFDAFNOG_02464 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
KFDAFNOG_02465 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFDAFNOG_02467 7.2e-175 corA P Mg2 transporter protein
KFDAFNOG_02468 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KFDAFNOG_02469 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KFDAFNOG_02471 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KFDAFNOG_02472 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KFDAFNOG_02473 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KFDAFNOG_02474 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KFDAFNOG_02475 6.9e-50 yqgV S Thiamine-binding protein
KFDAFNOG_02476 2.7e-199 yqgU
KFDAFNOG_02477 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KFDAFNOG_02478 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KFDAFNOG_02479 5.2e-181 glcK 2.7.1.2 G Glucokinase
KFDAFNOG_02480 3.1e-33 yqgQ S Protein conserved in bacteria
KFDAFNOG_02481 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KFDAFNOG_02482 2.5e-09 yqgO
KFDAFNOG_02483 6.7e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFDAFNOG_02484 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KFDAFNOG_02485 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KFDAFNOG_02487 3.5e-50 yqzD
KFDAFNOG_02488 7.3e-72 yqzC S YceG-like family
KFDAFNOG_02489 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KFDAFNOG_02490 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KFDAFNOG_02491 4.4e-158 pstA P Phosphate transport system permease
KFDAFNOG_02492 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KFDAFNOG_02493 3.4e-150 pstS P Phosphate
KFDAFNOG_02494 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KFDAFNOG_02495 2.5e-231 yqgE EGP Major facilitator superfamily
KFDAFNOG_02496 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KFDAFNOG_02497 4e-73 yqgC S protein conserved in bacteria
KFDAFNOG_02498 3.9e-131 yqgB S Protein of unknown function (DUF1189)
KFDAFNOG_02499 5.2e-47 yqfZ M LysM domain
KFDAFNOG_02500 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KFDAFNOG_02501 4.3e-62 yqfX S membrane
KFDAFNOG_02502 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KFDAFNOG_02503 1.9e-77 zur P Belongs to the Fur family
KFDAFNOG_02504 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KFDAFNOG_02505 7.9e-36 yqfT S Protein of unknown function (DUF2624)
KFDAFNOG_02506 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KFDAFNOG_02507 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KFDAFNOG_02508 3.5e-12 yqfQ S YqfQ-like protein
KFDAFNOG_02509 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFDAFNOG_02510 5.3e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFDAFNOG_02511 1.5e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
KFDAFNOG_02512 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KFDAFNOG_02513 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KFDAFNOG_02514 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KFDAFNOG_02515 4.5e-88 yaiI S Belongs to the UPF0178 family
KFDAFNOG_02516 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KFDAFNOG_02517 4.5e-112 ccpN K CBS domain
KFDAFNOG_02518 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KFDAFNOG_02519 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KFDAFNOG_02520 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
KFDAFNOG_02521 8.4e-19 S YqzL-like protein
KFDAFNOG_02522 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFDAFNOG_02523 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KFDAFNOG_02524 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KFDAFNOG_02525 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFDAFNOG_02526 0.0 yqfF S membrane-associated HD superfamily hydrolase
KFDAFNOG_02528 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
KFDAFNOG_02529 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KFDAFNOG_02530 2.7e-45 yqfC S sporulation protein YqfC
KFDAFNOG_02531 2.4e-21 yqfB
KFDAFNOG_02532 4.3e-122 yqfA S UPF0365 protein
KFDAFNOG_02533 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KFDAFNOG_02534 2.5e-61 yqeY S Yqey-like protein
KFDAFNOG_02535 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KFDAFNOG_02536 8.2e-158 yqeW P COG1283 Na phosphate symporter
KFDAFNOG_02537 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KFDAFNOG_02538 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KFDAFNOG_02539 6e-174 prmA J Methylates ribosomal protein L11
KFDAFNOG_02540 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KFDAFNOG_02541 0.0 dnaK O Heat shock 70 kDa protein
KFDAFNOG_02542 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFDAFNOG_02543 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KFDAFNOG_02544 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
KFDAFNOG_02545 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KFDAFNOG_02546 7.2e-53 yqxA S Protein of unknown function (DUF3679)
KFDAFNOG_02547 4.5e-222 spoIIP M stage II sporulation protein P
KFDAFNOG_02548 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KFDAFNOG_02549 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KFDAFNOG_02550 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
KFDAFNOG_02551 4.1e-15 S YqzM-like protein
KFDAFNOG_02552 0.0 comEC S Competence protein ComEC
KFDAFNOG_02553 4.7e-105 comEB 3.5.4.12 F ComE operon protein 2
KFDAFNOG_02554 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KFDAFNOG_02555 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KFDAFNOG_02556 2.9e-139 yqeM Q Methyltransferase
KFDAFNOG_02557 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KFDAFNOG_02558 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KFDAFNOG_02559 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFDAFNOG_02560 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KFDAFNOG_02561 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFDAFNOG_02562 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KFDAFNOG_02563 5.3e-95 yqeG S hydrolase of the HAD superfamily
KFDAFNOG_02565 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
KFDAFNOG_02566 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KFDAFNOG_02567 2.3e-105 yqeD S SNARE associated Golgi protein
KFDAFNOG_02568 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KFDAFNOG_02569 2e-132 yqeB
KFDAFNOG_02570 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
KFDAFNOG_02571 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_02572 1.4e-281 cisA2 L Recombinase
KFDAFNOG_02573 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
KFDAFNOG_02574 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
KFDAFNOG_02575 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_02576 2.1e-54 arsR K ArsR family transcriptional regulator
KFDAFNOG_02577 4.8e-145 yqcI S YqcI/YcgG family
KFDAFNOG_02578 1.6e-96 S Tetratricopeptide repeat
KFDAFNOG_02581 3.8e-277 A Pre-toxin TG
KFDAFNOG_02582 2.4e-101 S Suppressor of fused protein (SUFU)
KFDAFNOG_02585 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KFDAFNOG_02586 2.6e-68 S Bacteriophage holin family
KFDAFNOG_02587 3e-159 xepA
KFDAFNOG_02588 3.7e-10
KFDAFNOG_02589 4.1e-56 xkdW S XkdW protein
KFDAFNOG_02590 3.4e-197
KFDAFNOG_02591 9e-38
KFDAFNOG_02592 8.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KFDAFNOG_02593 2.2e-185 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KFDAFNOG_02594 5e-67 xkdS S Protein of unknown function (DUF2634)
KFDAFNOG_02595 1.1e-35 xkdR S Protein of unknown function (DUF2577)
KFDAFNOG_02596 5.1e-176 yqbQ 3.2.1.96 G NLP P60 protein
KFDAFNOG_02597 1.7e-112 xkdP S Lysin motif
KFDAFNOG_02598 0.0 xkdO L Transglycosylase SLT domain
KFDAFNOG_02599 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
KFDAFNOG_02601 3.6e-76 xkdM S Phage tail tube protein
KFDAFNOG_02602 5.5e-256 xkdK S Phage tail sheath C-terminal domain
KFDAFNOG_02603 3.2e-26
KFDAFNOG_02604 1.4e-77
KFDAFNOG_02605 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
KFDAFNOG_02606 6.7e-65 yqbH S Domain of unknown function (DUF3599)
KFDAFNOG_02607 2.1e-67 S Protein of unknown function (DUF3199)
KFDAFNOG_02608 3.6e-51 S YqbF, hypothetical protein domain
KFDAFNOG_02609 1.9e-167 xkdG S Phage capsid family
KFDAFNOG_02610 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KFDAFNOG_02611 2e-115
KFDAFNOG_02612 5.7e-169 S Phage Mu protein F like protein
KFDAFNOG_02613 5.9e-296 yqbA S portal protein
KFDAFNOG_02614 2.4e-253 S phage terminase, large subunit
KFDAFNOG_02615 6.3e-107 yqaS L DNA packaging
KFDAFNOG_02617 6.5e-81 L Transposase
KFDAFNOG_02618 1.6e-166
KFDAFNOG_02619 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
KFDAFNOG_02620 7.2e-74 rusA L Endodeoxyribonuclease RusA
KFDAFNOG_02622 5.9e-168 xkdC L IstB-like ATP binding protein
KFDAFNOG_02623 1e-122 3.1.3.16 L DnaD domain protein
KFDAFNOG_02624 2.5e-155 recT L RecT family
KFDAFNOG_02625 9.8e-180 yqaJ L YqaJ-like viral recombinase domain
KFDAFNOG_02629 1.2e-103
KFDAFNOG_02631 6.5e-37 K Helix-turn-helix XRE-family like proteins
KFDAFNOG_02632 1.1e-56 K sequence-specific DNA binding
KFDAFNOG_02634 1e-101 adk 2.7.4.3 F adenylate kinase activity
KFDAFNOG_02635 4.4e-94 yqaB E IrrE N-terminal-like domain
KFDAFNOG_02636 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFDAFNOG_02637 3.6e-112 tetR3 K Transcriptional regulator
KFDAFNOG_02638 2e-215 mepA V Multidrug transporter MatE
KFDAFNOG_02639 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KFDAFNOG_02640 5.4e-112 yrkJ S membrane transporter protein
KFDAFNOG_02641 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
KFDAFNOG_02642 9.3e-206 yrkH P Rhodanese Homology Domain
KFDAFNOG_02643 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
KFDAFNOG_02644 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
KFDAFNOG_02645 7.8e-39 yrkD S protein conserved in bacteria
KFDAFNOG_02646 5.5e-106 yrkC G Cupin domain
KFDAFNOG_02647 4.2e-147 bltR K helix_turn_helix, mercury resistance
KFDAFNOG_02648 3.9e-210 blt EGP Major facilitator Superfamily
KFDAFNOG_02649 5.9e-82 bltD 2.3.1.57 K FR47-like protein
KFDAFNOG_02650 2.5e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KFDAFNOG_02651 3.9e-16 S YrzO-like protein
KFDAFNOG_02652 1.6e-169 yrdR EG EamA-like transporter family
KFDAFNOG_02653 3e-159 yrdQ K Transcriptional regulator
KFDAFNOG_02654 2.3e-198 trkA P Oxidoreductase
KFDAFNOG_02655 4e-149 czcD P COG1230 Co Zn Cd efflux system component
KFDAFNOG_02656 1.3e-66 yodA S tautomerase
KFDAFNOG_02657 5e-162 gltR K LysR substrate binding domain
KFDAFNOG_02658 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
KFDAFNOG_02659 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KFDAFNOG_02660 9.6e-138 azlC E AzlC protein
KFDAFNOG_02661 5.3e-78 bkdR K helix_turn_helix ASNC type
KFDAFNOG_02662 1.1e-40 yrdF K ribonuclease inhibitor
KFDAFNOG_02663 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
KFDAFNOG_02664 3.3e-57 S Protein of unknown function (DUF2568)
KFDAFNOG_02665 2.4e-89 yrdA S DinB family
KFDAFNOG_02666 4.2e-166 aadK G Streptomycin adenylyltransferase
KFDAFNOG_02667 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KFDAFNOG_02668 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KFDAFNOG_02669 1.6e-123 yrpD S Domain of unknown function, YrpD
KFDAFNOG_02671 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KFDAFNOG_02672 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_02673 1.3e-187 yrpG C Aldo/keto reductase family
KFDAFNOG_02674 3.4e-223 yraO C Citrate transporter
KFDAFNOG_02675 3.4e-163 yraN K Transcriptional regulator
KFDAFNOG_02676 1.6e-205 yraM S PrpF protein
KFDAFNOG_02678 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KFDAFNOG_02679 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_02680 3.2e-155 S Alpha beta hydrolase
KFDAFNOG_02681 1.7e-60 T sh3 domain protein
KFDAFNOG_02682 2.4e-61 T sh3 domain protein
KFDAFNOG_02683 1.3e-66 E Glyoxalase-like domain
KFDAFNOG_02684 5.3e-37 yraG
KFDAFNOG_02685 6.4e-63 yraF M Spore coat protein
KFDAFNOG_02686 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KFDAFNOG_02687 2.6e-26 yraE
KFDAFNOG_02688 1.1e-49 yraD M Spore coat protein
KFDAFNOG_02689 4.3e-47 yraB K helix_turn_helix, mercury resistance
KFDAFNOG_02690 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
KFDAFNOG_02691 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
KFDAFNOG_02692 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KFDAFNOG_02693 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KFDAFNOG_02694 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KFDAFNOG_02695 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KFDAFNOG_02696 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KFDAFNOG_02697 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
KFDAFNOG_02698 0.0 levR K PTS system fructose IIA component
KFDAFNOG_02699 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_02700 3.6e-106 yrhP E LysE type translocator
KFDAFNOG_02701 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
KFDAFNOG_02702 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_02703 3.8e-151 rsiV S Protein of unknown function (DUF3298)
KFDAFNOG_02704 0.0 yrhL I Acyltransferase family
KFDAFNOG_02705 1e-18 yrhK S YrhK-like protein
KFDAFNOG_02706 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
KFDAFNOG_02707 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
KFDAFNOG_02708 1.5e-52 S dehydrogenases and related proteins
KFDAFNOG_02709 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
KFDAFNOG_02710 1.2e-100 EF ATP-grasp domain
KFDAFNOG_02711 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
KFDAFNOG_02712 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KFDAFNOG_02713 7.2e-104 Q TIGRFAM amino acid adenylation domain
KFDAFNOG_02714 8.3e-63 S ABC-2 family transporter protein
KFDAFNOG_02715 5.7e-64 S ABC-2 family transporter protein
KFDAFNOG_02716 9.4e-117 S ATPases associated with a variety of cellular activities
KFDAFNOG_02717 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
KFDAFNOG_02718 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
KFDAFNOG_02719 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KFDAFNOG_02720 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KFDAFNOG_02721 7.2e-95 yrhH Q methyltransferase
KFDAFNOG_02724 1.8e-142 focA P Formate nitrite
KFDAFNOG_02725 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
KFDAFNOG_02726 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KFDAFNOG_02727 1.4e-78 yrhD S Protein of unknown function (DUF1641)
KFDAFNOG_02728 4.6e-35 yrhC S YrhC-like protein
KFDAFNOG_02729 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KFDAFNOG_02730 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KFDAFNOG_02731 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KFDAFNOG_02732 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KFDAFNOG_02733 1e-25 yrzA S Protein of unknown function (DUF2536)
KFDAFNOG_02734 1.6e-62 yrrS S Protein of unknown function (DUF1510)
KFDAFNOG_02735 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KFDAFNOG_02736 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KFDAFNOG_02737 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KFDAFNOG_02738 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KFDAFNOG_02739 3.9e-173 yegQ O Peptidase U32
KFDAFNOG_02740 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
KFDAFNOG_02741 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFDAFNOG_02742 1.2e-45 yrzB S Belongs to the UPF0473 family
KFDAFNOG_02743 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFDAFNOG_02744 1.7e-41 yrzL S Belongs to the UPF0297 family
KFDAFNOG_02745 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFDAFNOG_02746 2.7e-170 yrrI S AI-2E family transporter
KFDAFNOG_02747 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KFDAFNOG_02748 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KFDAFNOG_02749 8e-109 gluC P ABC transporter
KFDAFNOG_02750 7.6e-107 glnP P ABC transporter
KFDAFNOG_02751 8e-08 S Protein of unknown function (DUF3918)
KFDAFNOG_02752 9.8e-31 yrzR
KFDAFNOG_02753 2.5e-80 yrrD S protein conserved in bacteria
KFDAFNOG_02754 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KFDAFNOG_02755 1.4e-15 S COG0457 FOG TPR repeat
KFDAFNOG_02756 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KFDAFNOG_02757 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
KFDAFNOG_02758 1.2e-70 cymR K Transcriptional regulator
KFDAFNOG_02759 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KFDAFNOG_02760 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KFDAFNOG_02761 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFDAFNOG_02762 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KFDAFNOG_02764 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
KFDAFNOG_02765 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KFDAFNOG_02766 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFDAFNOG_02767 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KFDAFNOG_02768 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KFDAFNOG_02769 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KFDAFNOG_02770 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KFDAFNOG_02771 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFDAFNOG_02772 9.4e-49 yrzD S Post-transcriptional regulator
KFDAFNOG_02773 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_02774 3e-111 yrbG S membrane
KFDAFNOG_02775 2.2e-73 yrzE S Protein of unknown function (DUF3792)
KFDAFNOG_02776 1.1e-38 yajC U Preprotein translocase subunit YajC
KFDAFNOG_02777 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KFDAFNOG_02778 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFDAFNOG_02779 2.6e-18 yrzS S Protein of unknown function (DUF2905)
KFDAFNOG_02780 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KFDAFNOG_02781 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KFDAFNOG_02782 4.8e-93 bofC S BofC C-terminal domain
KFDAFNOG_02783 4.5e-252 csbX EGP Major facilitator Superfamily
KFDAFNOG_02784 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KFDAFNOG_02785 6.5e-119 yrzF T serine threonine protein kinase
KFDAFNOG_02787 1.3e-50 S Family of unknown function (DUF5412)
KFDAFNOG_02788 4.5e-261 alsT E Sodium alanine symporter
KFDAFNOG_02789 1e-125 yebC K transcriptional regulatory protein
KFDAFNOG_02790 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KFDAFNOG_02791 8.3e-157 safA M spore coat assembly protein SafA
KFDAFNOG_02792 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFDAFNOG_02793 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KFDAFNOG_02794 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KFDAFNOG_02795 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
KFDAFNOG_02796 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
KFDAFNOG_02797 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
KFDAFNOG_02798 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KFDAFNOG_02799 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFDAFNOG_02800 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KFDAFNOG_02801 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KFDAFNOG_02802 4.1e-56 ysxB J ribosomal protein
KFDAFNOG_02803 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KFDAFNOG_02804 9.2e-161 spoIVFB S Stage IV sporulation protein
KFDAFNOG_02805 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KFDAFNOG_02806 4.7e-143 minD D Belongs to the ParA family
KFDAFNOG_02807 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KFDAFNOG_02808 1.4e-84 mreD M shape-determining protein
KFDAFNOG_02809 2.8e-157 mreC M Involved in formation and maintenance of cell shape
KFDAFNOG_02810 1.8e-184 mreB D Rod shape-determining protein MreB
KFDAFNOG_02811 1.3e-125 radC E Belongs to the UPF0758 family
KFDAFNOG_02812 8.3e-102 maf D septum formation protein Maf
KFDAFNOG_02813 8.4e-166 spoIIB S Sporulation related domain
KFDAFNOG_02814 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KFDAFNOG_02815 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KFDAFNOG_02816 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KFDAFNOG_02817 1.6e-25
KFDAFNOG_02818 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KFDAFNOG_02819 2.2e-222 spoVID M stage VI sporulation protein D
KFDAFNOG_02820 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KFDAFNOG_02821 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
KFDAFNOG_02822 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KFDAFNOG_02823 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KFDAFNOG_02824 3.6e-146 hemX O cytochrome C
KFDAFNOG_02825 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFDAFNOG_02826 1.4e-89 ysxD
KFDAFNOG_02827 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KFDAFNOG_02828 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFDAFNOG_02829 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KFDAFNOG_02830 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFDAFNOG_02831 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KFDAFNOG_02832 2.3e-187 ysoA H Tetratricopeptide repeat
KFDAFNOG_02833 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFDAFNOG_02834 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFDAFNOG_02835 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KFDAFNOG_02836 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFDAFNOG_02837 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFDAFNOG_02838 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KFDAFNOG_02839 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KFDAFNOG_02841 7.6e-82 ysnE K acetyltransferase
KFDAFNOG_02842 9.1e-134 ysnF S protein conserved in bacteria
KFDAFNOG_02844 7e-92 ysnB S Phosphoesterase
KFDAFNOG_02845 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFDAFNOG_02846 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFDAFNOG_02847 2.9e-196 gerM S COG5401 Spore germination protein
KFDAFNOG_02848 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KFDAFNOG_02849 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_02850 3.3e-30 gerE K Transcriptional regulator
KFDAFNOG_02851 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KFDAFNOG_02852 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KFDAFNOG_02853 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KFDAFNOG_02854 2.4e-107 sdhC C succinate dehydrogenase
KFDAFNOG_02855 1.2e-79 yslB S Protein of unknown function (DUF2507)
KFDAFNOG_02856 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KFDAFNOG_02857 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KFDAFNOG_02858 2e-52 trxA O Belongs to the thioredoxin family
KFDAFNOG_02859 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KFDAFNOG_02861 2.1e-177 etfA C Electron transfer flavoprotein
KFDAFNOG_02862 4.5e-135 etfB C Electron transfer flavoprotein
KFDAFNOG_02863 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KFDAFNOG_02864 2.7e-100 fadR K Transcriptional regulator
KFDAFNOG_02865 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KFDAFNOG_02866 7.3e-68 yshE S membrane
KFDAFNOG_02867 1.5e-149 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KFDAFNOG_02868 1.5e-231 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KFDAFNOG_02869 0.0 polX L COG1796 DNA polymerase IV (family X)
KFDAFNOG_02870 1.3e-85 cvpA S membrane protein, required for colicin V production
KFDAFNOG_02871 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KFDAFNOG_02872 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFDAFNOG_02873 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KFDAFNOG_02874 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFDAFNOG_02875 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFDAFNOG_02876 5.8e-32 sspI S Belongs to the SspI family
KFDAFNOG_02877 9.2e-206 ysfB KT regulator
KFDAFNOG_02878 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
KFDAFNOG_02879 5.8e-255 glcF C Glycolate oxidase
KFDAFNOG_02880 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
KFDAFNOG_02881 0.0 cstA T Carbon starvation protein
KFDAFNOG_02882 1.7e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KFDAFNOG_02883 3.8e-143 araQ G transport system permease
KFDAFNOG_02884 4.2e-167 araP G carbohydrate transport
KFDAFNOG_02885 2e-252 araN G carbohydrate transport
KFDAFNOG_02886 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KFDAFNOG_02887 6e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KFDAFNOG_02888 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KFDAFNOG_02889 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KFDAFNOG_02890 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KFDAFNOG_02891 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KFDAFNOG_02892 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
KFDAFNOG_02893 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KFDAFNOG_02894 7.5e-45 ysdA S Membrane
KFDAFNOG_02895 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFDAFNOG_02896 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KFDAFNOG_02897 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFDAFNOG_02899 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KFDAFNOG_02900 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KFDAFNOG_02901 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
KFDAFNOG_02902 0.0 lytS 2.7.13.3 T Histidine kinase
KFDAFNOG_02903 1.5e-149 ysaA S HAD-hyrolase-like
KFDAFNOG_02904 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFDAFNOG_02905 3.8e-159 ytxC S YtxC-like family
KFDAFNOG_02906 4.9e-111 ytxB S SNARE associated Golgi protein
KFDAFNOG_02907 3e-173 dnaI L Primosomal protein DnaI
KFDAFNOG_02908 3.5e-266 dnaB L Membrane attachment protein
KFDAFNOG_02909 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFDAFNOG_02910 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFDAFNOG_02911 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KFDAFNOG_02912 9.9e-67 ytcD K Transcriptional regulator
KFDAFNOG_02913 4.9e-205 ytbD EGP Major facilitator Superfamily
KFDAFNOG_02914 8.9e-161 ytbE S reductase
KFDAFNOG_02915 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KFDAFNOG_02916 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KFDAFNOG_02917 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KFDAFNOG_02918 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFDAFNOG_02919 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KFDAFNOG_02920 9.8e-68 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_02921 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KFDAFNOG_02922 1.8e-242 icd 1.1.1.42 C isocitrate
KFDAFNOG_02923 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KFDAFNOG_02924 4.7e-71 yeaL S membrane
KFDAFNOG_02925 9.9e-192 ytvI S sporulation integral membrane protein YtvI
KFDAFNOG_02926 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KFDAFNOG_02927 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KFDAFNOG_02928 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KFDAFNOG_02929 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KFDAFNOG_02930 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFDAFNOG_02931 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KFDAFNOG_02932 0.0 dnaE 2.7.7.7 L DNA polymerase
KFDAFNOG_02933 3.2e-56 ytrH S Sporulation protein YtrH
KFDAFNOG_02934 8.2e-69 ytrI
KFDAFNOG_02935 9.2e-29
KFDAFNOG_02936 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KFDAFNOG_02937 2.4e-47 ytpI S YtpI-like protein
KFDAFNOG_02938 8e-241 ytoI K transcriptional regulator containing CBS domains
KFDAFNOG_02939 1.2e-158 ytnM S membrane transporter protein
KFDAFNOG_02940 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
KFDAFNOG_02941 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KFDAFNOG_02942 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_02943 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
KFDAFNOG_02944 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_02945 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KFDAFNOG_02946 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
KFDAFNOG_02947 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
KFDAFNOG_02948 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
KFDAFNOG_02949 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
KFDAFNOG_02950 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
KFDAFNOG_02951 2.9e-173 ytlI K LysR substrate binding domain
KFDAFNOG_02952 1.7e-130 ytkL S Belongs to the UPF0173 family
KFDAFNOG_02953 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_02955 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
KFDAFNOG_02956 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KFDAFNOG_02957 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KFDAFNOG_02958 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFDAFNOG_02959 7e-165 ytxK 2.1.1.72 L DNA methylase
KFDAFNOG_02960 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KFDAFNOG_02961 8.7e-70 ytfJ S Sporulation protein YtfJ
KFDAFNOG_02962 5.6e-116 ytfI S Protein of unknown function (DUF2953)
KFDAFNOG_02963 1.3e-87 yteJ S RDD family
KFDAFNOG_02964 7.1e-181 sppA OU signal peptide peptidase SppA
KFDAFNOG_02965 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFDAFNOG_02966 0.0 ytcJ S amidohydrolase
KFDAFNOG_02967 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KFDAFNOG_02968 2e-29 sspB S spore protein
KFDAFNOG_02969 1.3e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFDAFNOG_02970 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
KFDAFNOG_02971 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
KFDAFNOG_02972 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KFDAFNOG_02973 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KFDAFNOG_02974 3.4e-109 yttP K Transcriptional regulator
KFDAFNOG_02975 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KFDAFNOG_02976 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KFDAFNOG_02977 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFDAFNOG_02979 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFDAFNOG_02980 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KFDAFNOG_02981 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KFDAFNOG_02982 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KFDAFNOG_02983 1.9e-225 acuC BQ histone deacetylase
KFDAFNOG_02984 1.4e-125 motS N Flagellar motor protein
KFDAFNOG_02985 2.1e-146 motA N flagellar motor
KFDAFNOG_02986 1.7e-182 ccpA K catabolite control protein A
KFDAFNOG_02987 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KFDAFNOG_02988 3.1e-53 ytxJ O Protein of unknown function (DUF2847)
KFDAFNOG_02989 6.6e-17 ytxH S COG4980 Gas vesicle protein
KFDAFNOG_02990 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KFDAFNOG_02991 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KFDAFNOG_02992 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KFDAFNOG_02993 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KFDAFNOG_02994 9.8e-149 ytpQ S Belongs to the UPF0354 family
KFDAFNOG_02995 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KFDAFNOG_02996 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KFDAFNOG_02997 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KFDAFNOG_02998 1.1e-50 ytzB S small secreted protein
KFDAFNOG_02999 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KFDAFNOG_03000 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KFDAFNOG_03001 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KFDAFNOG_03002 2e-45 ytzH S YtzH-like protein
KFDAFNOG_03003 1e-150 ytmP 2.7.1.89 M Phosphotransferase
KFDAFNOG_03004 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KFDAFNOG_03005 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KFDAFNOG_03006 1.3e-165 ytlQ
KFDAFNOG_03007 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KFDAFNOG_03008 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KFDAFNOG_03009 7.1e-272 pepV 3.5.1.18 E Dipeptidase
KFDAFNOG_03010 7.2e-226 pbuO S permease
KFDAFNOG_03011 5.3e-204 ythQ U Bacterial ABC transporter protein EcsB
KFDAFNOG_03012 3.6e-131 ythP V ABC transporter
KFDAFNOG_03013 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KFDAFNOG_03014 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KFDAFNOG_03015 1.2e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_03016 1.5e-230 ytfP S HI0933-like protein
KFDAFNOG_03017 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KFDAFNOG_03018 3.1e-26 yteV S Sporulation protein Cse60
KFDAFNOG_03019 4.8e-117 yteU S Integral membrane protein
KFDAFNOG_03020 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KFDAFNOG_03021 4.6e-73 yteS G transport
KFDAFNOG_03022 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KFDAFNOG_03023 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KFDAFNOG_03024 0.0 ytdP K Transcriptional regulator
KFDAFNOG_03025 5.2e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KFDAFNOG_03026 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
KFDAFNOG_03027 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KFDAFNOG_03028 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
KFDAFNOG_03029 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFDAFNOG_03030 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFDAFNOG_03031 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KFDAFNOG_03032 3.9e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KFDAFNOG_03033 5.8e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KFDAFNOG_03034 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
KFDAFNOG_03035 4.3e-189 msmR K Transcriptional regulator
KFDAFNOG_03036 1.8e-245 msmE G Bacterial extracellular solute-binding protein
KFDAFNOG_03037 1.4e-167 amyD P ABC transporter
KFDAFNOG_03038 1.1e-142 amyC P ABC transporter (permease)
KFDAFNOG_03039 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KFDAFNOG_03040 2.1e-51 ytwF P Sulfurtransferase
KFDAFNOG_03041 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KFDAFNOG_03042 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KFDAFNOG_03043 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KFDAFNOG_03044 7.3e-209 yttB EGP Major facilitator Superfamily
KFDAFNOG_03045 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
KFDAFNOG_03046 0.0 bceB V ABC transporter (permease)
KFDAFNOG_03047 1.1e-138 bceA V ABC transporter, ATP-binding protein
KFDAFNOG_03048 1.8e-184 T PhoQ Sensor
KFDAFNOG_03049 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_03050 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KFDAFNOG_03051 3.1e-127 ytrE V ABC transporter, ATP-binding protein
KFDAFNOG_03052 5.9e-148
KFDAFNOG_03053 8.3e-166 P ABC-2 family transporter protein
KFDAFNOG_03054 4.2e-161 ytrB P abc transporter atp-binding protein
KFDAFNOG_03055 5.1e-66 ytrA K GntR family transcriptional regulator
KFDAFNOG_03057 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KFDAFNOG_03058 2.1e-190 yhcC S Fe-S oxidoreductase
KFDAFNOG_03059 3.3e-106 ytqB J Putative rRNA methylase
KFDAFNOG_03060 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KFDAFNOG_03061 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KFDAFNOG_03062 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFDAFNOG_03063 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_03064 0.0 asnB 6.3.5.4 E Asparagine synthase
KFDAFNOG_03065 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFDAFNOG_03066 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KFDAFNOG_03067 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KFDAFNOG_03068 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KFDAFNOG_03069 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KFDAFNOG_03070 1.4e-144 ytlC P ABC transporter
KFDAFNOG_03071 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KFDAFNOG_03072 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KFDAFNOG_03073 5.4e-63 ytkC S Bacteriophage holin family
KFDAFNOG_03074 2.1e-76 dps P Belongs to the Dps family
KFDAFNOG_03076 2.4e-72 ytkA S YtkA-like
KFDAFNOG_03077 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KFDAFNOG_03078 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KFDAFNOG_03079 3.6e-41 rpmE2 J Ribosomal protein L31
KFDAFNOG_03080 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
KFDAFNOG_03081 1.2e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KFDAFNOG_03082 1.1e-24 S Domain of Unknown Function (DUF1540)
KFDAFNOG_03083 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KFDAFNOG_03084 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KFDAFNOG_03085 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KFDAFNOG_03086 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
KFDAFNOG_03087 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KFDAFNOG_03088 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KFDAFNOG_03089 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KFDAFNOG_03090 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KFDAFNOG_03091 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KFDAFNOG_03092 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
KFDAFNOG_03093 2.6e-132 dksA T COG1734 DnaK suppressor protein
KFDAFNOG_03094 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
KFDAFNOG_03095 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KFDAFNOG_03096 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KFDAFNOG_03097 3.6e-235 ytcC M Glycosyltransferase Family 4
KFDAFNOG_03099 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
KFDAFNOG_03100 1.8e-217 cotSA M Glycosyl transferases group 1
KFDAFNOG_03101 4.8e-204 cotI S Spore coat protein
KFDAFNOG_03102 9.9e-77 tspO T membrane
KFDAFNOG_03103 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KFDAFNOG_03104 1.6e-282 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KFDAFNOG_03105 2.2e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KFDAFNOG_03106 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KFDAFNOG_03107 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KFDAFNOG_03116 7.8e-08
KFDAFNOG_03117 1.3e-09
KFDAFNOG_03124 2e-08
KFDAFNOG_03129 3.4e-39 S COG NOG14552 non supervised orthologous group
KFDAFNOG_03130 5.7e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KFDAFNOG_03131 3.2e-92 M1-753 M FR47-like protein
KFDAFNOG_03132 7e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KFDAFNOG_03133 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KFDAFNOG_03134 3.9e-84 yuaE S DinB superfamily
KFDAFNOG_03135 2.3e-107 yuaD
KFDAFNOG_03136 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KFDAFNOG_03137 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KFDAFNOG_03138 1.1e-95 yuaC K Belongs to the GbsR family
KFDAFNOG_03139 2.2e-91 yuaB
KFDAFNOG_03140 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KFDAFNOG_03141 7.9e-236 ktrB P Potassium
KFDAFNOG_03142 1e-38 yiaA S yiaA/B two helix domain
KFDAFNOG_03143 7.1e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KFDAFNOG_03144 2.5e-270 yubD P Major Facilitator Superfamily
KFDAFNOG_03145 1.1e-86 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KFDAFNOG_03147 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KFDAFNOG_03148 1.8e-196 yubA S transporter activity
KFDAFNOG_03149 9.7e-183 ygjR S Oxidoreductase
KFDAFNOG_03150 1.7e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KFDAFNOG_03151 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KFDAFNOG_03152 1.5e-272 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KFDAFNOG_03153 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KFDAFNOG_03154 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KFDAFNOG_03155 3.3e-238 mcpA NT chemotaxis protein
KFDAFNOG_03156 5.5e-294 mcpA NT chemotaxis protein
KFDAFNOG_03157 4.5e-219 mcpA NT chemotaxis protein
KFDAFNOG_03158 3.2e-225 mcpA NT chemotaxis protein
KFDAFNOG_03159 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KFDAFNOG_03160 1.3e-35
KFDAFNOG_03161 6.3e-72 yugU S Uncharacterised protein family UPF0047
KFDAFNOG_03162 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KFDAFNOG_03163 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KFDAFNOG_03164 1.4e-116 yugP S Zn-dependent protease
KFDAFNOG_03165 2.3e-38
KFDAFNOG_03166 5.4e-53 mstX S Membrane-integrating protein Mistic
KFDAFNOG_03167 2.2e-182 yugO P COG1226 Kef-type K transport systems
KFDAFNOG_03168 1.3e-72 yugN S YugN-like family
KFDAFNOG_03170 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KFDAFNOG_03171 1.4e-228 yugK C Dehydrogenase
KFDAFNOG_03172 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KFDAFNOG_03173 1.1e-34 yuzA S Domain of unknown function (DUF378)
KFDAFNOG_03174 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KFDAFNOG_03175 2.1e-199 yugH 2.6.1.1 E Aminotransferase
KFDAFNOG_03176 1.6e-85 alaR K Transcriptional regulator
KFDAFNOG_03177 4.9e-156 yugF I Hydrolase
KFDAFNOG_03178 4.6e-39 yugE S Domain of unknown function (DUF1871)
KFDAFNOG_03179 6.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KFDAFNOG_03180 1.3e-232 T PhoQ Sensor
KFDAFNOG_03181 7.4e-70 kapB G Kinase associated protein B
KFDAFNOG_03182 1.9e-115 kapD L the KinA pathway to sporulation
KFDAFNOG_03184 2.1e-183 yuxJ EGP Major facilitator Superfamily
KFDAFNOG_03185 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KFDAFNOG_03186 6.3e-75 yuxK S protein conserved in bacteria
KFDAFNOG_03187 6.3e-78 yufK S Family of unknown function (DUF5366)
KFDAFNOG_03188 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KFDAFNOG_03189 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KFDAFNOG_03190 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KFDAFNOG_03191 2.3e-271 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KFDAFNOG_03192 1.9e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KFDAFNOG_03193 1.2e-166 yufQ S Belongs to the binding-protein-dependent transport system permease family
KFDAFNOG_03194 1.3e-233 maeN C COG3493 Na citrate symporter
KFDAFNOG_03195 3.2e-14
KFDAFNOG_03196 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KFDAFNOG_03197 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KFDAFNOG_03198 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KFDAFNOG_03199 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KFDAFNOG_03200 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KFDAFNOG_03201 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KFDAFNOG_03202 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KFDAFNOG_03203 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KFDAFNOG_03204 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_03205 0.0 comP 2.7.13.3 T Histidine kinase
KFDAFNOG_03207 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
KFDAFNOG_03210 3.2e-22 yuzC
KFDAFNOG_03211 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KFDAFNOG_03212 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KFDAFNOG_03213 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
KFDAFNOG_03214 7.9e-67 yueI S Protein of unknown function (DUF1694)
KFDAFNOG_03215 2.8e-38 yueH S YueH-like protein
KFDAFNOG_03216 2.1e-32 yueG S Spore germination protein gerPA/gerPF
KFDAFNOG_03217 1.9e-190 yueF S transporter activity
KFDAFNOG_03218 6.1e-72 S Protein of unknown function (DUF2283)
KFDAFNOG_03219 2.9e-24 S Protein of unknown function (DUF2642)
KFDAFNOG_03220 4.8e-96 yueE S phosphohydrolase
KFDAFNOG_03221 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_03222 6.6e-65 yueC S Family of unknown function (DUF5383)
KFDAFNOG_03223 0.0 esaA S type VII secretion protein EsaA
KFDAFNOG_03224 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KFDAFNOG_03225 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KFDAFNOG_03226 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KFDAFNOG_03227 2.8e-45 esxA S Belongs to the WXG100 family
KFDAFNOG_03228 6.5e-229 yukF QT Transcriptional regulator
KFDAFNOG_03229 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KFDAFNOG_03230 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KFDAFNOG_03231 3.8e-36 mbtH S MbtH-like protein
KFDAFNOG_03232 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_03233 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KFDAFNOG_03234 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KFDAFNOG_03235 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
KFDAFNOG_03236 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03237 1.3e-167 besA S Putative esterase
KFDAFNOG_03238 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
KFDAFNOG_03239 1.3e-92 bioY S Biotin biosynthesis protein
KFDAFNOG_03240 3.9e-211 yuiF S antiporter
KFDAFNOG_03241 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFDAFNOG_03242 1.2e-77 yuiD S protein conserved in bacteria
KFDAFNOG_03243 5.6e-118 yuiC S protein conserved in bacteria
KFDAFNOG_03244 8.4e-27 yuiB S Putative membrane protein
KFDAFNOG_03245 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
KFDAFNOG_03246 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
KFDAFNOG_03248 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KFDAFNOG_03249 1e-116 paiB K Putative FMN-binding domain
KFDAFNOG_03250 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_03251 3.7e-63 erpA S Belongs to the HesB IscA family
KFDAFNOG_03252 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KFDAFNOG_03253 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFDAFNOG_03254 3.2e-39 yuzB S Belongs to the UPF0349 family
KFDAFNOG_03255 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KFDAFNOG_03256 3.5e-57 yuzD S protein conserved in bacteria
KFDAFNOG_03257 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KFDAFNOG_03258 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KFDAFNOG_03259 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KFDAFNOG_03260 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFDAFNOG_03261 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
KFDAFNOG_03262 2e-199 yutH S Spore coat protein
KFDAFNOG_03263 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KFDAFNOG_03264 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KFDAFNOG_03265 1e-75 yutE S Protein of unknown function DUF86
KFDAFNOG_03266 9.7e-48 yutD S protein conserved in bacteria
KFDAFNOG_03267 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KFDAFNOG_03268 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFDAFNOG_03269 4.5e-196 lytH M Peptidase, M23
KFDAFNOG_03270 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
KFDAFNOG_03271 4.8e-48 yunC S Domain of unknown function (DUF1805)
KFDAFNOG_03272 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KFDAFNOG_03273 2e-141 yunE S membrane transporter protein
KFDAFNOG_03274 4.3e-171 yunF S Protein of unknown function DUF72
KFDAFNOG_03275 3e-62 yunG
KFDAFNOG_03276 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KFDAFNOG_03277 7.5e-302 pucR QT COG2508 Regulator of polyketide synthase expression
KFDAFNOG_03278 3.3e-234 pbuX F Permease family
KFDAFNOG_03279 1.3e-58 pbuX F xanthine
KFDAFNOG_03280 1.7e-149 pbuX F xanthine
KFDAFNOG_03281 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KFDAFNOG_03282 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KFDAFNOG_03283 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KFDAFNOG_03284 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KFDAFNOG_03285 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KFDAFNOG_03286 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KFDAFNOG_03287 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KFDAFNOG_03289 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KFDAFNOG_03290 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KFDAFNOG_03291 2.4e-169 bsn L Ribonuclease
KFDAFNOG_03292 1.2e-205 msmX P Belongs to the ABC transporter superfamily
KFDAFNOG_03293 1.1e-135 yurK K UTRA
KFDAFNOG_03294 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KFDAFNOG_03295 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
KFDAFNOG_03296 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
KFDAFNOG_03297 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KFDAFNOG_03298 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KFDAFNOG_03299 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KFDAFNOG_03300 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KFDAFNOG_03302 1e-41
KFDAFNOG_03303 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_03304 3.5e-271 sufB O FeS cluster assembly
KFDAFNOG_03305 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KFDAFNOG_03306 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFDAFNOG_03307 1.4e-245 sufD O assembly protein SufD
KFDAFNOG_03308 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KFDAFNOG_03309 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFDAFNOG_03310 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
KFDAFNOG_03311 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KFDAFNOG_03312 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFDAFNOG_03313 2.4e-56 yusD S SCP-2 sterol transfer family
KFDAFNOG_03314 5.6e-55 traF CO Thioredoxin
KFDAFNOG_03315 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KFDAFNOG_03316 1.1e-39 yusG S Protein of unknown function (DUF2553)
KFDAFNOG_03317 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KFDAFNOG_03318 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KFDAFNOG_03319 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KFDAFNOG_03320 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
KFDAFNOG_03321 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KFDAFNOG_03322 4e-08 S YuzL-like protein
KFDAFNOG_03323 2.4e-164 fadM E Proline dehydrogenase
KFDAFNOG_03324 5.1e-40
KFDAFNOG_03325 5.4e-53 yusN M Coat F domain
KFDAFNOG_03326 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
KFDAFNOG_03327 8.5e-293 yusP P Major facilitator superfamily
KFDAFNOG_03328 2.7e-64 yusQ S Tautomerase enzyme
KFDAFNOG_03329 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03330 5.7e-158 yusT K LysR substrate binding domain
KFDAFNOG_03331 3.8e-47 yusU S Protein of unknown function (DUF2573)
KFDAFNOG_03332 1e-153 yusV 3.6.3.34 HP ABC transporter
KFDAFNOG_03333 2.5e-66 S YusW-like protein
KFDAFNOG_03334 1.9e-301 pepF2 E COG1164 Oligoendopeptidase F
KFDAFNOG_03335 8.9e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03336 1.2e-79 dps P Ferritin-like domain
KFDAFNOG_03337 7.8e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFDAFNOG_03338 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_03339 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KFDAFNOG_03340 1.3e-157 yuxN K Transcriptional regulator
KFDAFNOG_03341 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KFDAFNOG_03342 2.3e-24 S Protein of unknown function (DUF3970)
KFDAFNOG_03343 1.4e-246 gerAA EG Spore germination protein
KFDAFNOG_03344 9.1e-198 gerAB E Spore germination protein
KFDAFNOG_03345 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
KFDAFNOG_03346 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_03347 3.5e-186 vraS 2.7.13.3 T Histidine kinase
KFDAFNOG_03348 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KFDAFNOG_03349 2.3e-127 liaG S Putative adhesin
KFDAFNOG_03350 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KFDAFNOG_03351 5.6e-62 liaI S membrane
KFDAFNOG_03352 1.4e-226 yvqJ EGP Major facilitator Superfamily
KFDAFNOG_03353 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
KFDAFNOG_03354 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KFDAFNOG_03355 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_03356 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KFDAFNOG_03357 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03358 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
KFDAFNOG_03359 0.0 T PhoQ Sensor
KFDAFNOG_03360 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_03361 3.6e-22
KFDAFNOG_03362 9.5e-98 yvrI K RNA polymerase
KFDAFNOG_03363 2.4e-19 S YvrJ protein family
KFDAFNOG_03364 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
KFDAFNOG_03365 3.8e-64 yvrL S Regulatory protein YrvL
KFDAFNOG_03366 3.4e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KFDAFNOG_03367 2.1e-123 macB V ABC transporter, ATP-binding protein
KFDAFNOG_03368 2.6e-174 M Efflux transporter rnd family, mfp subunit
KFDAFNOG_03369 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KFDAFNOG_03370 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_03371 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFDAFNOG_03372 7.6e-177 fhuD P ABC transporter
KFDAFNOG_03374 4.9e-236 yvsH E Arginine ornithine antiporter
KFDAFNOG_03375 6.5e-16 S Small spore protein J (Spore_SspJ)
KFDAFNOG_03376 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KFDAFNOG_03377 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KFDAFNOG_03378 1.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KFDAFNOG_03379 3e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KFDAFNOG_03380 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KFDAFNOG_03381 1.1e-155 yvgN S reductase
KFDAFNOG_03382 5.4e-86 yvgO
KFDAFNOG_03383 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KFDAFNOG_03384 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KFDAFNOG_03385 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFDAFNOG_03386 0.0 helD 3.6.4.12 L DNA helicase
KFDAFNOG_03387 4.1e-107 yvgT S membrane
KFDAFNOG_03388 7.2e-71 bdbC O Required for disulfide bond formation in some proteins
KFDAFNOG_03389 2.7e-104 bdbD O Thioredoxin
KFDAFNOG_03390 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KFDAFNOG_03391 0.0 copA 3.6.3.54 P P-type ATPase
KFDAFNOG_03392 1.5e-29 copZ P Copper resistance protein CopZ
KFDAFNOG_03393 2.2e-48 csoR S transcriptional
KFDAFNOG_03394 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
KFDAFNOG_03395 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KFDAFNOG_03396 0.0 yvaC S Fusaric acid resistance protein-like
KFDAFNOG_03397 1.3e-72 yvaD S Family of unknown function (DUF5360)
KFDAFNOG_03398 6.3e-55 yvaE P Small Multidrug Resistance protein
KFDAFNOG_03399 4.1e-101 K Bacterial regulatory proteins, tetR family
KFDAFNOG_03400 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03402 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFDAFNOG_03403 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KFDAFNOG_03404 5.6e-143 est 3.1.1.1 S Carboxylesterase
KFDAFNOG_03405 2.4e-23 secG U Preprotein translocase subunit SecG
KFDAFNOG_03406 3.7e-153 yvaM S Serine aminopeptidase, S33
KFDAFNOG_03407 7.5e-36 yvzC K Transcriptional
KFDAFNOG_03408 4e-69 K transcriptional
KFDAFNOG_03409 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
KFDAFNOG_03410 2.2e-54 yodB K transcriptional
KFDAFNOG_03411 1.1e-213 NT chemotaxis protein
KFDAFNOG_03412 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KFDAFNOG_03413 2e-169 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KFDAFNOG_03414 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KFDAFNOG_03415 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KFDAFNOG_03416 3.3e-60 yvbF K Belongs to the GbsR family
KFDAFNOG_03417 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KFDAFNOG_03418 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KFDAFNOG_03419 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KFDAFNOG_03420 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KFDAFNOG_03421 3.5e-97 yvbF K Belongs to the GbsR family
KFDAFNOG_03422 2.7e-101 yvbG U UPF0056 membrane protein
KFDAFNOG_03423 8.6e-113 yvbH S YvbH-like oligomerisation region
KFDAFNOG_03424 1.3e-120 exoY M Membrane
KFDAFNOG_03425 0.0 tcaA S response to antibiotic
KFDAFNOG_03426 3.1e-75 yvbK 3.1.3.25 K acetyltransferase
KFDAFNOG_03427 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KFDAFNOG_03428 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KFDAFNOG_03429 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KFDAFNOG_03430 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KFDAFNOG_03431 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KFDAFNOG_03432 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KFDAFNOG_03433 1.6e-252 araE EGP Major facilitator Superfamily
KFDAFNOG_03434 5.5e-203 araR K transcriptional
KFDAFNOG_03435 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_03436 3.3e-158 yvbU K Transcriptional regulator
KFDAFNOG_03437 7.2e-156 yvbV EG EamA-like transporter family
KFDAFNOG_03438 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KFDAFNOG_03439 6.1e-196 yvbX S Glycosyl hydrolase
KFDAFNOG_03440 9.7e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KFDAFNOG_03441 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KFDAFNOG_03442 6.5e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KFDAFNOG_03443 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_03444 9.9e-200 desK 2.7.13.3 T Histidine kinase
KFDAFNOG_03445 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
KFDAFNOG_03446 6.6e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KFDAFNOG_03447 1.6e-249 galA 3.2.1.89 G arabinogalactan
KFDAFNOG_03448 0.0 lacA 3.2.1.23 G beta-galactosidase
KFDAFNOG_03449 7.2e-150 ganQ P transport
KFDAFNOG_03450 1.1e-231 malC P COG1175 ABC-type sugar transport systems, permease components
KFDAFNOG_03451 1.9e-231 cycB G COG2182 Maltose-binding periplasmic proteins domains
KFDAFNOG_03452 1.8e-184 lacR K Transcriptional regulator
KFDAFNOG_03453 1e-112 yvfI K COG2186 Transcriptional regulators
KFDAFNOG_03454 4.8e-307 yvfH C L-lactate permease
KFDAFNOG_03455 2.3e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KFDAFNOG_03456 1e-31 yvfG S YvfG protein
KFDAFNOG_03457 1.7e-187 yvfF GM Exopolysaccharide biosynthesis protein
KFDAFNOG_03458 2.5e-222 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KFDAFNOG_03459 1.1e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KFDAFNOG_03460 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KFDAFNOG_03461 2.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_03462 3.5e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KFDAFNOG_03463 1.2e-202 epsI GM pyruvyl transferase
KFDAFNOG_03464 2e-194 epsH GT2 S Glycosyltransferase like family 2
KFDAFNOG_03465 1.1e-206 epsG S EpsG family
KFDAFNOG_03466 1.9e-217 epsF GT4 M Glycosyl transferases group 1
KFDAFNOG_03467 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KFDAFNOG_03468 2.9e-223 epsD GT4 M Glycosyl transferase 4-like
KFDAFNOG_03469 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KFDAFNOG_03470 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KFDAFNOG_03471 4e-122 ywqC M biosynthesis protein
KFDAFNOG_03472 6.3e-76 slr K transcriptional
KFDAFNOG_03473 3e-68 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KFDAFNOG_03474 1e-190 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KFDAFNOG_03476 1.7e-92 padC Q Phenolic acid decarboxylase
KFDAFNOG_03477 5e-73 MA20_18690 S Protein of unknown function (DUF3237)
KFDAFNOG_03478 2.6e-126 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KFDAFNOG_03479 7.6e-263 pbpE V Beta-lactamase
KFDAFNOG_03480 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
KFDAFNOG_03481 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KFDAFNOG_03482 3.9e-295 yveA E amino acid
KFDAFNOG_03483 2.6e-106 yvdT K Transcriptional regulator
KFDAFNOG_03484 1.5e-50 ykkC P Small Multidrug Resistance protein
KFDAFNOG_03485 4.1e-50 sugE P Small Multidrug Resistance protein
KFDAFNOG_03486 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
KFDAFNOG_03487 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
KFDAFNOG_03488 1.2e-182 S Patatin-like phospholipase
KFDAFNOG_03490 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KFDAFNOG_03491 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KFDAFNOG_03492 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KFDAFNOG_03493 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KFDAFNOG_03494 2.9e-154 malA S Protein of unknown function (DUF1189)
KFDAFNOG_03495 1.5e-147 malD P transport
KFDAFNOG_03496 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KFDAFNOG_03497 2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KFDAFNOG_03498 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KFDAFNOG_03499 1.5e-172 yvdE K Transcriptional regulator
KFDAFNOG_03500 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KFDAFNOG_03501 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
KFDAFNOG_03502 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KFDAFNOG_03503 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KFDAFNOG_03504 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFDAFNOG_03505 0.0 yxdM V ABC transporter (permease)
KFDAFNOG_03506 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KFDAFNOG_03507 1.2e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KFDAFNOG_03508 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_03509 1.8e-33
KFDAFNOG_03510 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KFDAFNOG_03511 1.6e-36 crh G Phosphocarrier protein Chr
KFDAFNOG_03512 1.4e-170 whiA K May be required for sporulation
KFDAFNOG_03513 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KFDAFNOG_03514 5.7e-166 rapZ S Displays ATPase and GTPase activities
KFDAFNOG_03515 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KFDAFNOG_03516 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KFDAFNOG_03517 1.4e-102 usp CBM50 M protein conserved in bacteria
KFDAFNOG_03518 2.4e-278 S COG0457 FOG TPR repeat
KFDAFNOG_03519 0.0 msbA2 3.6.3.44 V ABC transporter
KFDAFNOG_03521 1e-252
KFDAFNOG_03522 2.1e-70
KFDAFNOG_03523 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KFDAFNOG_03524 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KFDAFNOG_03525 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFDAFNOG_03526 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KFDAFNOG_03527 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KFDAFNOG_03528 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFDAFNOG_03529 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KFDAFNOG_03530 1.3e-218 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KFDAFNOG_03531 3.8e-139 yvpB NU protein conserved in bacteria
KFDAFNOG_03532 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KFDAFNOG_03533 7.3e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KFDAFNOG_03534 1.2e-117 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KFDAFNOG_03535 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
KFDAFNOG_03536 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFDAFNOG_03537 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFDAFNOG_03538 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KFDAFNOG_03539 4.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KFDAFNOG_03540 1.8e-133 yvoA K transcriptional
KFDAFNOG_03541 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KFDAFNOG_03542 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_03543 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
KFDAFNOG_03544 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
KFDAFNOG_03545 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_03546 6.1e-203 yvmA EGP Major facilitator Superfamily
KFDAFNOG_03547 1.2e-50 yvlD S Membrane
KFDAFNOG_03548 2.6e-26 pspB KT PspC domain
KFDAFNOG_03549 7.5e-168 yvlB S Putative adhesin
KFDAFNOG_03550 8e-49 yvlA
KFDAFNOG_03551 6.7e-34 yvkN
KFDAFNOG_03552 9.2e-78 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFDAFNOG_03553 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KFDAFNOG_03554 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KFDAFNOG_03555 1.2e-30 csbA S protein conserved in bacteria
KFDAFNOG_03556 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KFDAFNOG_03557 7e-101 yvkB K Transcriptional regulator
KFDAFNOG_03558 7.9e-228 yvkA EGP Major facilitator Superfamily
KFDAFNOG_03559 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFDAFNOG_03560 5.3e-56 swrA S Swarming motility protein
KFDAFNOG_03561 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KFDAFNOG_03562 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KFDAFNOG_03563 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KFDAFNOG_03564 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KFDAFNOG_03565 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KFDAFNOG_03566 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KFDAFNOG_03567 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KFDAFNOG_03568 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KFDAFNOG_03569 2.8e-66
KFDAFNOG_03570 1.4e-08 fliT S bacterial-type flagellum organization
KFDAFNOG_03571 2.9e-69 fliS N flagellar protein FliS
KFDAFNOG_03572 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KFDAFNOG_03573 6.1e-57 flaG N flagellar protein FlaG
KFDAFNOG_03574 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KFDAFNOG_03575 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFDAFNOG_03576 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KFDAFNOG_03577 2.6e-50 yviE
KFDAFNOG_03578 1.1e-156 flgL N Belongs to the bacterial flagellin family
KFDAFNOG_03579 1.2e-264 flgK N flagellar hook-associated protein
KFDAFNOG_03580 2.4e-78 flgN NOU FlgN protein
KFDAFNOG_03581 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
KFDAFNOG_03582 7e-74 yvyF S flagellar protein
KFDAFNOG_03583 2.7e-129 comFC S Phosphoribosyl transferase domain
KFDAFNOG_03584 5.7e-46 comFB S Late competence development protein ComFB
KFDAFNOG_03585 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KFDAFNOG_03586 7.3e-155 degV S protein conserved in bacteria
KFDAFNOG_03587 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KFDAFNOG_03588 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KFDAFNOG_03589 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KFDAFNOG_03590 6e-163 yvhJ K Transcriptional regulator
KFDAFNOG_03591 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KFDAFNOG_03592 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KFDAFNOG_03593 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KFDAFNOG_03594 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
KFDAFNOG_03595 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
KFDAFNOG_03596 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KFDAFNOG_03597 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KFDAFNOG_03598 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KFDAFNOG_03599 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KFDAFNOG_03600 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KFDAFNOG_03601 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KFDAFNOG_03602 6e-38
KFDAFNOG_03603 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KFDAFNOG_03604 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KFDAFNOG_03605 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KFDAFNOG_03606 6.5e-57
KFDAFNOG_03607 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KFDAFNOG_03608 7.5e-93 ggaA M Glycosyltransferase like family 2
KFDAFNOG_03609 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFDAFNOG_03610 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KFDAFNOG_03611 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KFDAFNOG_03612 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KFDAFNOG_03613 4.1e-150 tagG GM Transport permease protein
KFDAFNOG_03614 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFDAFNOG_03615 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
KFDAFNOG_03616 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KFDAFNOG_03617 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KFDAFNOG_03618 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFDAFNOG_03619 3.5e-260
KFDAFNOG_03620 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KFDAFNOG_03621 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KFDAFNOG_03622 1.2e-261 gerBA EG Spore germination protein
KFDAFNOG_03623 1.5e-192 gerBB E Spore germination protein
KFDAFNOG_03624 3.2e-206 gerAC S Spore germination protein
KFDAFNOG_03625 1.9e-248 ywtG EGP Major facilitator Superfamily
KFDAFNOG_03626 8.4e-171 ywtF K Transcriptional regulator
KFDAFNOG_03627 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KFDAFNOG_03628 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KFDAFNOG_03629 3.6e-21 ywtC
KFDAFNOG_03630 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KFDAFNOG_03631 8.6e-70 pgsC S biosynthesis protein
KFDAFNOG_03632 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KFDAFNOG_03633 9.3e-178 rbsR K transcriptional
KFDAFNOG_03634 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFDAFNOG_03635 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KFDAFNOG_03636 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KFDAFNOG_03637 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
KFDAFNOG_03638 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KFDAFNOG_03639 8.7e-93 batE T Sh3 type 3 domain protein
KFDAFNOG_03640 8e-48 ywsA S Protein of unknown function (DUF3892)
KFDAFNOG_03641 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KFDAFNOG_03642 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KFDAFNOG_03643 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KFDAFNOG_03644 1.1e-169 alsR K LysR substrate binding domain
KFDAFNOG_03645 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFDAFNOG_03646 3.1e-124 ywrJ
KFDAFNOG_03647 8.2e-131 cotB
KFDAFNOG_03648 3.5e-210 cotH M Spore Coat
KFDAFNOG_03649 3.7e-12
KFDAFNOG_03650 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KFDAFNOG_03651 1.4e-53 S Domain of unknown function (DUF4181)
KFDAFNOG_03652 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KFDAFNOG_03653 8e-82 ywrC K Transcriptional regulator
KFDAFNOG_03654 1.2e-103 ywrB P Chromate transporter
KFDAFNOG_03655 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
KFDAFNOG_03657 1.1e-100 ywqN S NAD(P)H-dependent
KFDAFNOG_03658 1.4e-161 K Transcriptional regulator
KFDAFNOG_03659 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KFDAFNOG_03660 3.9e-25
KFDAFNOG_03661 1.9e-82 ywqJ S Pre-toxin TG
KFDAFNOG_03662 5.2e-17
KFDAFNOG_03663 7.9e-43
KFDAFNOG_03664 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
KFDAFNOG_03665 8.6e-38 ywqI S Family of unknown function (DUF5344)
KFDAFNOG_03666 9.7e-23 S Domain of unknown function (DUF5082)
KFDAFNOG_03667 1.4e-152 ywqG S Domain of unknown function (DUF1963)
KFDAFNOG_03668 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KFDAFNOG_03669 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KFDAFNOG_03670 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KFDAFNOG_03671 2e-116 ywqC M biosynthesis protein
KFDAFNOG_03672 1.2e-17
KFDAFNOG_03673 1.4e-308 ywqB S SWIM zinc finger
KFDAFNOG_03674 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KFDAFNOG_03675 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KFDAFNOG_03676 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KFDAFNOG_03677 3.7e-57 ssbB L Single-stranded DNA-binding protein
KFDAFNOG_03678 3.8e-66 ywpG
KFDAFNOG_03679 1.1e-66 ywpF S YwpF-like protein
KFDAFNOG_03680 1.2e-49 srtA 3.4.22.70 M Sortase family
KFDAFNOG_03681 7e-153 ywpD T Histidine kinase
KFDAFNOG_03682 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KFDAFNOG_03683 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KFDAFNOG_03684 8.8e-198 S aspartate phosphatase
KFDAFNOG_03685 3.7e-140 flhP N flagellar basal body
KFDAFNOG_03686 9.9e-125 flhO N flagellar basal body
KFDAFNOG_03687 3.5e-180 mbl D Rod shape-determining protein
KFDAFNOG_03688 3e-44 spoIIID K Stage III sporulation protein D
KFDAFNOG_03689 2.1e-70 ywoH K COG1846 Transcriptional regulators
KFDAFNOG_03690 3.9e-210 ywoG EGP Major facilitator Superfamily
KFDAFNOG_03691 2.8e-231 ywoF P Right handed beta helix region
KFDAFNOG_03692 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KFDAFNOG_03693 9.8e-242 ywoD EGP Major facilitator superfamily
KFDAFNOG_03694 4e-104 phzA Q Isochorismatase family
KFDAFNOG_03695 4.1e-75
KFDAFNOG_03696 2.5e-225 amt P Ammonium transporter
KFDAFNOG_03697 1.6e-58 nrgB K Belongs to the P(II) protein family
KFDAFNOG_03698 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KFDAFNOG_03699 3e-72 ywnJ S VanZ like family
KFDAFNOG_03700 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KFDAFNOG_03701 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KFDAFNOG_03702 8.9e-10 ywnC S Family of unknown function (DUF5362)
KFDAFNOG_03703 2.2e-70 ywnF S Family of unknown function (DUF5392)
KFDAFNOG_03704 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFDAFNOG_03705 5e-142 mta K transcriptional
KFDAFNOG_03706 2.6e-59 ywnC S Family of unknown function (DUF5362)
KFDAFNOG_03707 1.6e-114 ywnB S NAD(P)H-binding
KFDAFNOG_03708 1.7e-64 ywnA K Transcriptional regulator
KFDAFNOG_03709 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KFDAFNOG_03710 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KFDAFNOG_03711 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KFDAFNOG_03713 3.8e-11 csbD K CsbD-like
KFDAFNOG_03714 3e-84 ywmF S Peptidase M50
KFDAFNOG_03715 1.3e-103 S response regulator aspartate phosphatase
KFDAFNOG_03716 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFDAFNOG_03717 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KFDAFNOG_03719 3.6e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KFDAFNOG_03720 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KFDAFNOG_03721 3.2e-176 spoIID D Stage II sporulation protein D
KFDAFNOG_03722 3.6e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFDAFNOG_03723 8.2e-134 ywmB S TATA-box binding
KFDAFNOG_03724 1.3e-32 ywzB S membrane
KFDAFNOG_03725 4.3e-88 ywmA
KFDAFNOG_03726 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KFDAFNOG_03727 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFDAFNOG_03728 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFDAFNOG_03729 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFDAFNOG_03730 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFDAFNOG_03731 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFDAFNOG_03732 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFDAFNOG_03733 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KFDAFNOG_03734 2.5e-62 atpI S ATP synthase
KFDAFNOG_03735 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFDAFNOG_03736 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFDAFNOG_03737 7.2e-95 ywlG S Belongs to the UPF0340 family
KFDAFNOG_03738 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KFDAFNOG_03739 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFDAFNOG_03740 1.7e-91 mntP P Probably functions as a manganese efflux pump
KFDAFNOG_03741 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KFDAFNOG_03742 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KFDAFNOG_03743 3e-111 spoIIR S stage II sporulation protein R
KFDAFNOG_03744 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
KFDAFNOG_03746 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KFDAFNOG_03747 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFDAFNOG_03748 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_03749 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KFDAFNOG_03750 8.6e-160 ywkB S Membrane transport protein
KFDAFNOG_03751 0.0 sfcA 1.1.1.38 C malic enzyme
KFDAFNOG_03752 1.6e-103 tdk 2.7.1.21 F thymidine kinase
KFDAFNOG_03753 1.1e-32 rpmE J Binds the 23S rRNA
KFDAFNOG_03754 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFDAFNOG_03755 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KFDAFNOG_03756 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFDAFNOG_03757 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFDAFNOG_03758 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KFDAFNOG_03759 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KFDAFNOG_03760 5.1e-90 ywjG S Domain of unknown function (DUF2529)
KFDAFNOG_03761 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KFDAFNOG_03762 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KFDAFNOG_03763 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KFDAFNOG_03764 0.0 fadF C COG0247 Fe-S oxidoreductase
KFDAFNOG_03765 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KFDAFNOG_03766 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KFDAFNOG_03767 2.7e-42 ywjC
KFDAFNOG_03768 4.8e-96 ywjB H RibD C-terminal domain
KFDAFNOG_03769 0.0 ywjA V ABC transporter
KFDAFNOG_03770 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFDAFNOG_03771 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
KFDAFNOG_03772 1.1e-93 narJ 1.7.5.1 C nitrate reductase
KFDAFNOG_03773 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
KFDAFNOG_03774 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFDAFNOG_03775 7e-86 arfM T cyclic nucleotide binding
KFDAFNOG_03776 1.7e-139 ywiC S YwiC-like protein
KFDAFNOG_03777 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KFDAFNOG_03778 2.3e-213 narK P COG2223 Nitrate nitrite transporter
KFDAFNOG_03779 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KFDAFNOG_03780 4.7e-73 ywiB S protein conserved in bacteria
KFDAFNOG_03781 1e-07 S Bacteriocin subtilosin A
KFDAFNOG_03782 4.9e-270 C Fe-S oxidoreductases
KFDAFNOG_03784 3.3e-132 cbiO V ABC transporter
KFDAFNOG_03785 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KFDAFNOG_03786 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
KFDAFNOG_03787 1.6e-249 L Peptidase, M16
KFDAFNOG_03789 4.7e-244 ywhL CO amine dehydrogenase activity
KFDAFNOG_03790 2.3e-198 ywhK CO amine dehydrogenase activity
KFDAFNOG_03791 3.1e-79 S aspartate phosphatase
KFDAFNOG_03793 1.6e-26 ywhH S Aminoacyl-tRNA editing domain
KFDAFNOG_03794 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KFDAFNOG_03795 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KFDAFNOG_03796 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KFDAFNOG_03797 3.6e-49
KFDAFNOG_03798 5.2e-95 ywhD S YwhD family
KFDAFNOG_03799 5.1e-119 ywhC S Peptidase family M50
KFDAFNOG_03800 7.9e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KFDAFNOG_03801 9.5e-71 ywhA K Transcriptional regulator
KFDAFNOG_03802 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFDAFNOG_03804 1.3e-236 mmr U Major Facilitator Superfamily
KFDAFNOG_03805 6.2e-79 yffB K Transcriptional regulator
KFDAFNOG_03806 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
KFDAFNOG_03807 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
KFDAFNOG_03808 3.1e-36 ywzC S Belongs to the UPF0741 family
KFDAFNOG_03809 1.6e-111 rsfA_1
KFDAFNOG_03810 2.2e-157 ywfM EG EamA-like transporter family
KFDAFNOG_03811 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KFDAFNOG_03812 1.1e-156 cysL K Transcriptional regulator
KFDAFNOG_03813 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KFDAFNOG_03814 1.1e-146 ywfI C May function as heme-dependent peroxidase
KFDAFNOG_03815 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_03816 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
KFDAFNOG_03817 1.9e-209 bacE EGP Major facilitator Superfamily
KFDAFNOG_03818 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KFDAFNOG_03819 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KFDAFNOG_03820 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KFDAFNOG_03821 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KFDAFNOG_03822 6e-206 ywfA EGP Major facilitator Superfamily
KFDAFNOG_03823 4.8e-249 lysP E amino acid
KFDAFNOG_03824 0.0 rocB E arginine degradation protein
KFDAFNOG_03825 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KFDAFNOG_03826 8.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KFDAFNOG_03827 3.4e-77
KFDAFNOG_03828 1.3e-86 spsL 5.1.3.13 M Spore Coat
KFDAFNOG_03829 2.2e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KFDAFNOG_03830 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KFDAFNOG_03831 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KFDAFNOG_03832 1.5e-183 spsG M Spore Coat
KFDAFNOG_03833 1e-128 spsF M Spore Coat
KFDAFNOG_03834 6e-213 spsE 2.5.1.56 M acid synthase
KFDAFNOG_03835 1.7e-162 spsD 2.3.1.210 K Spore Coat
KFDAFNOG_03836 1.1e-222 spsC E Belongs to the DegT DnrJ EryC1 family
KFDAFNOG_03837 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
KFDAFNOG_03838 4.5e-143 spsA M Spore Coat
KFDAFNOG_03839 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KFDAFNOG_03840 4.3e-59 ywdK S small membrane protein
KFDAFNOG_03841 3.7e-238 ywdJ F Xanthine uracil
KFDAFNOG_03842 6.6e-48 ywdI S Family of unknown function (DUF5327)
KFDAFNOG_03843 1e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KFDAFNOG_03844 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFDAFNOG_03845 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KFDAFNOG_03846 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KFDAFNOG_03847 2e-28 ywdA
KFDAFNOG_03848 7.5e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KFDAFNOG_03849 7.3e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_03850 5.7e-138 focA P Formate/nitrite transporter
KFDAFNOG_03851 7e-150 sacT K transcriptional antiterminator
KFDAFNOG_03853 0.0 vpr O Belongs to the peptidase S8 family
KFDAFNOG_03854 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_03855 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KFDAFNOG_03856 8.6e-202 rodA D Belongs to the SEDS family
KFDAFNOG_03857 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KFDAFNOG_03858 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KFDAFNOG_03859 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KFDAFNOG_03860 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFDAFNOG_03861 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KFDAFNOG_03862 1e-35 ywzA S membrane
KFDAFNOG_03863 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KFDAFNOG_03864 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KFDAFNOG_03865 9.5e-60 gtcA S GtrA-like protein
KFDAFNOG_03866 1.1e-121 ywcC K transcriptional regulator
KFDAFNOG_03868 9.8e-49 ywcB S Protein of unknown function, DUF485
KFDAFNOG_03869 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFDAFNOG_03870 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KFDAFNOG_03871 3.2e-223 ywbN P Dyp-type peroxidase family protein
KFDAFNOG_03872 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
KFDAFNOG_03873 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
KFDAFNOG_03874 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KFDAFNOG_03875 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KFDAFNOG_03876 4.3e-153 ywbI K Transcriptional regulator
KFDAFNOG_03877 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KFDAFNOG_03878 2.3e-111 ywbG M effector of murein hydrolase
KFDAFNOG_03879 8.1e-208 ywbF EGP Major facilitator Superfamily
KFDAFNOG_03880 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KFDAFNOG_03881 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
KFDAFNOG_03882 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KFDAFNOG_03883 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
KFDAFNOG_03884 8.3e-125 ywbB S Protein of unknown function (DUF2711)
KFDAFNOG_03885 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KFDAFNOG_03886 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
KFDAFNOG_03887 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_03888 7.6e-152 sacY K transcriptional antiterminator
KFDAFNOG_03889 4.5e-168 gspA M General stress
KFDAFNOG_03890 1.5e-124 ywaF S Integral membrane protein
KFDAFNOG_03891 1.2e-86 ywaE K Transcriptional regulator
KFDAFNOG_03892 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFDAFNOG_03893 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KFDAFNOG_03894 4e-92 K Helix-turn-helix XRE-family like proteins
KFDAFNOG_03895 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
KFDAFNOG_03896 8.8e-130 ynfM EGP Major facilitator Superfamily
KFDAFNOG_03897 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KFDAFNOG_03898 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KFDAFNOG_03899 5e-14 S D-Ala-teichoic acid biosynthesis protein
KFDAFNOG_03900 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_03901 3.6e-232 dltB M membrane protein involved in D-alanine export
KFDAFNOG_03902 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KFDAFNOG_03903 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KFDAFNOG_03904 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_03905 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KFDAFNOG_03906 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KFDAFNOG_03907 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KFDAFNOG_03908 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KFDAFNOG_03909 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KFDAFNOG_03910 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KFDAFNOG_03911 1.1e-19 yxzF
KFDAFNOG_03912 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KFDAFNOG_03913 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KFDAFNOG_03914 1.6e-211 yxlH EGP Major facilitator Superfamily
KFDAFNOG_03915 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KFDAFNOG_03916 8.2e-165 yxlF V ABC transporter, ATP-binding protein
KFDAFNOG_03917 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KFDAFNOG_03918 1.4e-30
KFDAFNOG_03919 1.6e-46 yxlC S Family of unknown function (DUF5345)
KFDAFNOG_03920 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KFDAFNOG_03921 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KFDAFNOG_03922 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFDAFNOG_03923 0.0 cydD V ATP-binding protein
KFDAFNOG_03924 4e-309 cydD V ATP-binding
KFDAFNOG_03925 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KFDAFNOG_03926 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
KFDAFNOG_03927 1.5e-229 cimH C COG3493 Na citrate symporter
KFDAFNOG_03928 9.4e-311 3.4.24.84 O Peptidase family M48
KFDAFNOG_03930 9.9e-152 yxkH G Polysaccharide deacetylase
KFDAFNOG_03931 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KFDAFNOG_03932 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
KFDAFNOG_03933 1.1e-270 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KFDAFNOG_03934 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFDAFNOG_03935 2.8e-74 yxkC S Domain of unknown function (DUF4352)
KFDAFNOG_03936 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KFDAFNOG_03937 7.7e-77 S Protein of unknown function (DUF1453)
KFDAFNOG_03938 4.6e-190 yxjM T Signal transduction histidine kinase
KFDAFNOG_03939 9.8e-115 K helix_turn_helix, Lux Regulon
KFDAFNOG_03940 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KFDAFNOG_03942 1.4e-86 yxjI S LURP-one-related
KFDAFNOG_03943 1.2e-221 yxjG 2.1.1.14 E Methionine synthase
KFDAFNOG_03944 1e-220 yxjG 2.1.1.14 E Methionine synthase
KFDAFNOG_03945 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KFDAFNOG_03946 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KFDAFNOG_03947 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFDAFNOG_03948 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
KFDAFNOG_03949 5.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
KFDAFNOG_03950 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFDAFNOG_03951 1.5e-102 T Domain of unknown function (DUF4163)
KFDAFNOG_03952 3e-47 yxiS
KFDAFNOG_03953 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KFDAFNOG_03954 6.6e-224 citH C Citrate transporter
KFDAFNOG_03955 3.6e-142 exoK GH16 M licheninase activity
KFDAFNOG_03956 8.3e-151 licT K transcriptional antiterminator
KFDAFNOG_03957 2e-110
KFDAFNOG_03958 7.3e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
KFDAFNOG_03959 3.3e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KFDAFNOG_03960 2.3e-212 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KFDAFNOG_03963 1.6e-48 yxiJ S YxiJ-like protein
KFDAFNOG_03964 1.2e-96 yxiI S Protein of unknown function (DUF2716)
KFDAFNOG_03965 3.8e-81
KFDAFNOG_03966 4.9e-46
KFDAFNOG_03967 3.7e-75 yxiG
KFDAFNOG_03968 6.4e-63
KFDAFNOG_03969 1.7e-84
KFDAFNOG_03970 1.5e-71 yxxG
KFDAFNOG_03971 0.0 wapA M COG3209 Rhs family protein
KFDAFNOG_03972 1.4e-167 yxxF EG EamA-like transporter family
KFDAFNOG_03973 1.1e-72 yxiE T Belongs to the universal stress protein A family
KFDAFNOG_03974 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KFDAFNOG_03975 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KFDAFNOG_03976 3.6e-51
KFDAFNOG_03977 2.2e-78 S SMI1 / KNR4 family
KFDAFNOG_03978 0.0 S nuclease activity
KFDAFNOG_03979 3.6e-39 yxiC S Family of unknown function (DUF5344)
KFDAFNOG_03980 2.1e-21 S Domain of unknown function (DUF5082)
KFDAFNOG_03981 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KFDAFNOG_03982 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KFDAFNOG_03983 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
KFDAFNOG_03984 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFDAFNOG_03985 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KFDAFNOG_03986 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KFDAFNOG_03987 4.3e-204 lysP E amino acid
KFDAFNOG_03988 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KFDAFNOG_03989 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFDAFNOG_03990 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KFDAFNOG_03991 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KFDAFNOG_03992 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
KFDAFNOG_03993 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
KFDAFNOG_03994 2e-255 yxeQ S MmgE/PrpD family
KFDAFNOG_03995 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
KFDAFNOG_03996 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KFDAFNOG_03997 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
KFDAFNOG_03998 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
KFDAFNOG_03999 7.5e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KFDAFNOG_04000 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFDAFNOG_04002 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KFDAFNOG_04003 6.2e-151 yidA S hydrolases of the HAD superfamily
KFDAFNOG_04006 1.3e-20 yxeE
KFDAFNOG_04007 1.9e-16 yxeD
KFDAFNOG_04008 8.5e-69
KFDAFNOG_04009 5.1e-176 fhuD P ABC transporter
KFDAFNOG_04010 3.4e-58 yxeA S Protein of unknown function (DUF1093)
KFDAFNOG_04011 0.0 yxdM V ABC transporter (permease)
KFDAFNOG_04012 9.4e-141 yxdL V ABC transporter, ATP-binding protein
KFDAFNOG_04013 6.9e-181 T PhoQ Sensor
KFDAFNOG_04014 2.1e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_04015 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KFDAFNOG_04016 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KFDAFNOG_04017 8.6e-167 iolH G Xylose isomerase-like TIM barrel
KFDAFNOG_04018 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KFDAFNOG_04019 5.1e-235 iolF EGP Major facilitator Superfamily
KFDAFNOG_04020 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KFDAFNOG_04021 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KFDAFNOG_04022 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KFDAFNOG_04023 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KFDAFNOG_04024 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KFDAFNOG_04025 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KFDAFNOG_04026 8.3e-176 iolS C Aldo keto reductase
KFDAFNOG_04028 8.3e-48 yxcD S Protein of unknown function (DUF2653)
KFDAFNOG_04029 2.3e-246 csbC EGP Major facilitator Superfamily
KFDAFNOG_04030 0.0 htpG O Molecular chaperone. Has ATPase activity
KFDAFNOG_04032 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
KFDAFNOG_04033 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
KFDAFNOG_04034 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KFDAFNOG_04035 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
KFDAFNOG_04036 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
KFDAFNOG_04037 3.3e-127 yxbB Q Met-10+ like-protein
KFDAFNOG_04038 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
KFDAFNOG_04039 1.1e-86 yxnB
KFDAFNOG_04040 0.0 asnB 6.3.5.4 E Asparagine synthase
KFDAFNOG_04041 7.6e-214 yxaM U MFS_1 like family
KFDAFNOG_04042 6.8e-93 S PQQ-like domain
KFDAFNOG_04043 3.5e-65 S Family of unknown function (DUF5391)
KFDAFNOG_04044 1.1e-75 yxaI S membrane protein domain
KFDAFNOG_04045 1.4e-228 P Protein of unknown function (DUF418)
KFDAFNOG_04046 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
KFDAFNOG_04047 1.2e-100 yxaF K Transcriptional regulator
KFDAFNOG_04048 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KFDAFNOG_04049 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KFDAFNOG_04050 5.2e-50 S LrgA family
KFDAFNOG_04051 1.3e-117 yxaC M effector of murein hydrolase
KFDAFNOG_04052 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
KFDAFNOG_04053 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KFDAFNOG_04054 2.8e-126 gntR K transcriptional
KFDAFNOG_04055 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KFDAFNOG_04056 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
KFDAFNOG_04057 1.8e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KFDAFNOG_04058 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KFDAFNOG_04059 1.9e-286 ahpF O Alkyl hydroperoxide reductase
KFDAFNOG_04060 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KFDAFNOG_04061 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
KFDAFNOG_04062 1.9e-124 yydK K Transcriptional regulator
KFDAFNOG_04063 1.6e-118 S ABC-2 family transporter protein
KFDAFNOG_04064 1.6e-109 prrC P ABC transporter
KFDAFNOG_04065 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KFDAFNOG_04066 1.3e-202 S SIR2-like domain
KFDAFNOG_04067 1.1e-180 L DNA synthesis involved in DNA repair
KFDAFNOG_04068 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFDAFNOG_04069 1.1e-09 S YyzF-like protein
KFDAFNOG_04070 1.3e-67
KFDAFNOG_04071 1.5e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KFDAFNOG_04073 1.7e-30 yycQ S Protein of unknown function (DUF2651)
KFDAFNOG_04074 5.4e-201 yycP
KFDAFNOG_04075 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KFDAFNOG_04076 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
KFDAFNOG_04077 1.1e-187 S aspartate phosphatase
KFDAFNOG_04079 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KFDAFNOG_04080 1.3e-260 rocE E amino acid
KFDAFNOG_04081 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KFDAFNOG_04082 7.4e-16
KFDAFNOG_04083 2.8e-94
KFDAFNOG_04084 2.3e-24 S Sporulation delaying protein SdpA
KFDAFNOG_04085 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KFDAFNOG_04086 1.5e-40 sdpR K transcriptional
KFDAFNOG_04087 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KFDAFNOG_04088 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KFDAFNOG_04089 3.4e-94 K PFAM response regulator receiver
KFDAFNOG_04090 1.2e-73 S Peptidase propeptide and YPEB domain
KFDAFNOG_04091 3.8e-34 S Peptidase propeptide and YPEB domain
KFDAFNOG_04092 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFDAFNOG_04093 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KFDAFNOG_04094 7.3e-155 yycI S protein conserved in bacteria
KFDAFNOG_04095 4.9e-257 yycH S protein conserved in bacteria
KFDAFNOG_04096 0.0 vicK 2.7.13.3 T Histidine kinase
KFDAFNOG_04097 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KFDAFNOG_04102 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFDAFNOG_04103 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_04104 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KFDAFNOG_04105 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KFDAFNOG_04107 1.9e-15 yycC K YycC-like protein
KFDAFNOG_04108 8.4e-221 yeaN P COG2807 Cyanate permease
KFDAFNOG_04109 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFDAFNOG_04110 2.2e-73 rplI J binds to the 23S rRNA
KFDAFNOG_04111 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KFDAFNOG_04112 6.4e-160 yybS S membrane
KFDAFNOG_04114 5.1e-68 cotF M Spore coat protein
KFDAFNOG_04115 1.7e-66 ydeP3 K Transcriptional regulator
KFDAFNOG_04116 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KFDAFNOG_04117 7.3e-61
KFDAFNOG_04119 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KFDAFNOG_04120 9.7e-111 K TipAS antibiotic-recognition domain
KFDAFNOG_04121 5.3e-123
KFDAFNOG_04122 2.9e-66 yybH S SnoaL-like domain
KFDAFNOG_04123 6.2e-122 yybG S Pentapeptide repeat-containing protein
KFDAFNOG_04124 1.8e-215 ynfM EGP Major facilitator Superfamily
KFDAFNOG_04125 4.5e-163 yybE K Transcriptional regulator
KFDAFNOG_04126 7.2e-78 yjcF S Acetyltransferase (GNAT) domain
KFDAFNOG_04127 1.9e-75 yybC
KFDAFNOG_04128 4e-124 S Metallo-beta-lactamase superfamily
KFDAFNOG_04129 5.6e-77 yybA 2.3.1.57 K transcriptional
KFDAFNOG_04130 3.2e-69 yjcF S Acetyltransferase (GNAT) domain
KFDAFNOG_04131 2.5e-96 yyaS S Membrane
KFDAFNOG_04132 3.2e-92 yyaR K Acetyltransferase (GNAT) domain
KFDAFNOG_04133 1.7e-65 yyaQ S YjbR
KFDAFNOG_04134 1.8e-104 yyaP 1.5.1.3 H RibD C-terminal domain
KFDAFNOG_04135 3.3e-245 tetL EGP Major facilitator Superfamily
KFDAFNOG_04136 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KFDAFNOG_04137 6.4e-165 yyaK S CAAX protease self-immunity
KFDAFNOG_04138 6.1e-244 EGP Major facilitator superfamily
KFDAFNOG_04139 9.6e-95 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KFDAFNOG_04140 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KFDAFNOG_04141 9.9e-177 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KFDAFNOG_04142 3.7e-142 xth 3.1.11.2 L exodeoxyribonuclease III
KFDAFNOG_04143 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFDAFNOG_04144 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KFDAFNOG_04145 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
KFDAFNOG_04146 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KFDAFNOG_04147 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KFDAFNOG_04148 2.3e-33 yyzM S protein conserved in bacteria
KFDAFNOG_04149 8.1e-177 yyaD S Membrane
KFDAFNOG_04150 1.6e-111 yyaC S Sporulation protein YyaC
KFDAFNOG_04151 2.1e-149 spo0J K Belongs to the ParB family
KFDAFNOG_04152 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KFDAFNOG_04153 9.6e-74 S Bacterial PH domain
KFDAFNOG_04154 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KFDAFNOG_04155 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KFDAFNOG_04156 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KFDAFNOG_04157 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFDAFNOG_04158 6.5e-108 jag S single-stranded nucleic acid binding R3H
KFDAFNOG_04159 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KFDAFNOG_04160 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)