ORF_ID e_value Gene_name EC_number CAZy COGs Description
HDBIHKAD_00001 1.5e-119 L Transposase
HDBIHKAD_00002 1.1e-158 S Membrane protein involved in the export of O-antigen and teichoic acid
HDBIHKAD_00003 3.7e-38 L Transposase and inactivated derivatives
HDBIHKAD_00004 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HDBIHKAD_00005 3.6e-11
HDBIHKAD_00006 9e-13 ytgB S Transglycosylase associated protein
HDBIHKAD_00007 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
HDBIHKAD_00008 1.5e-42 S COG NOG38524 non supervised orthologous group
HDBIHKAD_00009 3.3e-217 yceI EGP Major facilitator Superfamily
HDBIHKAD_00010 1.1e-153 nadC 1.4.3.16, 2.4.2.19 H Quinolinate phosphoribosyl transferase, C-terminal domain
HDBIHKAD_00011 1.6e-84 L PFAM Integrase catalytic region
HDBIHKAD_00013 4.5e-79 L Helix-turn-helix domain
HDBIHKAD_00015 8.3e-37 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDBIHKAD_00016 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HDBIHKAD_00017 1.2e-23 S Family of unknown function (DUF5388)
HDBIHKAD_00018 0.0 traA L MobA/MobL family
HDBIHKAD_00019 8.1e-169 wbbI M transferase activity, transferring glycosyl groups
HDBIHKAD_00020 8.8e-40 L Transposase
HDBIHKAD_00023 2.1e-26
HDBIHKAD_00024 1.7e-39
HDBIHKAD_00025 3.6e-57
HDBIHKAD_00026 1.6e-35 relB L Addiction module antitoxin, RelB DinJ family
HDBIHKAD_00027 1.7e-38 sirR K Helix-turn-helix diphteria tox regulatory element
HDBIHKAD_00029 4.4e-127 terC P integral membrane protein, YkoY family
HDBIHKAD_00030 1.1e-49 L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_00031 3.9e-303 3.2.1.96 G Glycosyl hydrolase family 85
HDBIHKAD_00032 4.8e-224 3.2.1.96 G Glycosyl hydrolase family 85
HDBIHKAD_00033 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDBIHKAD_00034 4e-209 msmK P Belongs to the ABC transporter superfamily
HDBIHKAD_00035 5.5e-258 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HDBIHKAD_00036 1.6e-149 malA S maltodextrose utilization protein MalA
HDBIHKAD_00037 1.4e-161 malD P ABC transporter permease
HDBIHKAD_00038 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
HDBIHKAD_00039 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
HDBIHKAD_00040 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HDBIHKAD_00041 2e-180 yvdE K helix_turn _helix lactose operon repressor
HDBIHKAD_00042 1e-190 malR K Transcriptional regulator, LacI family
HDBIHKAD_00043 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_00044 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HDBIHKAD_00045 5.5e-101 dhaL 2.7.1.121 S Dak2
HDBIHKAD_00046 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDBIHKAD_00047 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HDBIHKAD_00048 1.9e-92 K Bacterial regulatory proteins, tetR family
HDBIHKAD_00050 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HDBIHKAD_00051 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
HDBIHKAD_00052 1.1e-116 K Transcriptional regulator
HDBIHKAD_00053 4.3e-297 M Exporter of polyketide antibiotics
HDBIHKAD_00054 2e-169 yjjC V ABC transporter
HDBIHKAD_00055 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HDBIHKAD_00056 9.1e-89
HDBIHKAD_00057 7.6e-149
HDBIHKAD_00058 3e-134
HDBIHKAD_00059 8.3e-54 K Transcriptional regulator PadR-like family
HDBIHKAD_00060 1.6e-129 K UbiC transcription regulator-associated domain protein
HDBIHKAD_00062 2.5e-98 S UPF0397 protein
HDBIHKAD_00063 0.0 ykoD P ABC transporter, ATP-binding protein
HDBIHKAD_00064 1.9e-150 cbiQ P cobalt transport
HDBIHKAD_00065 4e-209 C Oxidoreductase
HDBIHKAD_00066 2.2e-258
HDBIHKAD_00067 7.8e-49
HDBIHKAD_00068 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HDBIHKAD_00069 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HDBIHKAD_00070 1.2e-165 1.1.1.65 C Aldo keto reductase
HDBIHKAD_00071 3.4e-160 S reductase
HDBIHKAD_00073 2.3e-215 yeaN P Transporter, major facilitator family protein
HDBIHKAD_00074 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_00075 4.7e-227 mdtG EGP Major facilitator Superfamily
HDBIHKAD_00076 5.8e-82 S Protein of unknown function (DUF3021)
HDBIHKAD_00077 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
HDBIHKAD_00078 1.2e-74 papX3 K Transcriptional regulator
HDBIHKAD_00079 3.6e-111 S NADPH-dependent FMN reductase
HDBIHKAD_00080 1.6e-28 KT PspC domain
HDBIHKAD_00081 2.9e-142 2.4.2.3 F Phosphorylase superfamily
HDBIHKAD_00082 0.0 pacL1 P P-type ATPase
HDBIHKAD_00083 3.3e-149 ydjP I Alpha/beta hydrolase family
HDBIHKAD_00084 2.6e-121
HDBIHKAD_00085 2.6e-250 yifK E Amino acid permease
HDBIHKAD_00086 3.4e-85 F NUDIX domain
HDBIHKAD_00087 9.8e-302 L HIRAN domain
HDBIHKAD_00088 4.3e-135 S peptidase C26
HDBIHKAD_00089 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HDBIHKAD_00090 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HDBIHKAD_00091 1.3e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HDBIHKAD_00092 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HDBIHKAD_00093 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
HDBIHKAD_00094 1.4e-150 larE S NAD synthase
HDBIHKAD_00095 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_00096 2.5e-74 larC 4.99.1.12 S Protein of unknown function DUF111
HDBIHKAD_00097 1.8e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HDBIHKAD_00098 3.5e-121 larB S AIR carboxylase
HDBIHKAD_00099 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HDBIHKAD_00100 2.1e-120 K Crp-like helix-turn-helix domain
HDBIHKAD_00101 4.8e-182 nikMN P PDGLE domain
HDBIHKAD_00102 2.6e-149 P Cobalt transport protein
HDBIHKAD_00103 7.8e-129 cbiO P ABC transporter
HDBIHKAD_00104 4.8e-40
HDBIHKAD_00105 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HDBIHKAD_00106 3.7e-134 plnD K LytTr DNA-binding domain
HDBIHKAD_00107 2e-93 2.7.13.3 T GHKL domain
HDBIHKAD_00109 4.9e-102 2.7.8.12 GT2 S Glycosyltransferase like family 2
HDBIHKAD_00110 4.5e-171 L Integrase core domain
HDBIHKAD_00111 2.5e-46 L Transposase
HDBIHKAD_00112 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HDBIHKAD_00113 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HDBIHKAD_00114 1.7e-19
HDBIHKAD_00116 1.2e-134 D Cellulose biosynthesis protein BcsQ
HDBIHKAD_00117 1e-53 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HDBIHKAD_00118 3.7e-31 tnp2PF3 L manually curated
HDBIHKAD_00119 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
HDBIHKAD_00120 3.7e-31 KT PspC domain protein
HDBIHKAD_00121 3e-80 ydhK M Protein of unknown function (DUF1541)
HDBIHKAD_00122 2.4e-189 L PFAM Integrase, catalytic core
HDBIHKAD_00123 2e-132 S Cysteine-rich secretory protein family
HDBIHKAD_00124 3e-22 lytE M LysM domain protein
HDBIHKAD_00126 6.2e-117 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDBIHKAD_00127 2.1e-105 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDBIHKAD_00128 3.5e-268 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HDBIHKAD_00129 3.9e-26
HDBIHKAD_00130 1.4e-95 D Cellulose biosynthesis protein BcsQ
HDBIHKAD_00131 1.7e-52 M Lysin motif
HDBIHKAD_00132 4.5e-121 S CAAX protease self-immunity
HDBIHKAD_00133 2.5e-114 V CAAX protease self-immunity
HDBIHKAD_00134 7.1e-121 yclH V ABC transporter
HDBIHKAD_00135 2.9e-183 yclI V MacB-like periplasmic core domain
HDBIHKAD_00136 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HDBIHKAD_00137 1.1e-106 tag 3.2.2.20 L glycosylase
HDBIHKAD_00138 0.0 ydgH S MMPL family
HDBIHKAD_00139 3.1e-104 K transcriptional regulator
HDBIHKAD_00140 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HDBIHKAD_00141 1.3e-47
HDBIHKAD_00142 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HDBIHKAD_00143 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDBIHKAD_00144 2.1e-41
HDBIHKAD_00145 9.9e-57
HDBIHKAD_00146 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_00147 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
HDBIHKAD_00148 4.1e-49
HDBIHKAD_00149 7e-127 K Transcriptional regulatory protein, C terminal
HDBIHKAD_00150 9.8e-250 T PhoQ Sensor
HDBIHKAD_00151 3.3e-65 K helix_turn_helix, mercury resistance
HDBIHKAD_00152 1.1e-251 ydiC1 EGP Major facilitator Superfamily
HDBIHKAD_00153 1.4e-40
HDBIHKAD_00154 5.9e-38
HDBIHKAD_00155 5.1e-116
HDBIHKAD_00156 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HDBIHKAD_00157 3.7e-120 K Bacterial regulatory proteins, tetR family
HDBIHKAD_00158 1.8e-72 K Transcriptional regulator
HDBIHKAD_00159 3.5e-70
HDBIHKAD_00160 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HDBIHKAD_00161 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDBIHKAD_00162 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HDBIHKAD_00163 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HDBIHKAD_00164 1.4e-144
HDBIHKAD_00165 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HDBIHKAD_00166 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HDBIHKAD_00167 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HDBIHKAD_00168 3.5e-129 treR K UTRA
HDBIHKAD_00169 2.9e-42
HDBIHKAD_00170 7.3e-43 S Protein of unknown function (DUF2089)
HDBIHKAD_00171 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HDBIHKAD_00172 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HDBIHKAD_00173 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HDBIHKAD_00174 1.3e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HDBIHKAD_00175 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HDBIHKAD_00176 3.5e-97 yieF S NADPH-dependent FMN reductase
HDBIHKAD_00177 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
HDBIHKAD_00178 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
HDBIHKAD_00179 7.7e-62
HDBIHKAD_00180 6.2e-94
HDBIHKAD_00181 1.2e-49
HDBIHKAD_00182 6.2e-57 trxA1 O Belongs to the thioredoxin family
HDBIHKAD_00183 2.1e-73
HDBIHKAD_00184 4.7e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HDBIHKAD_00185 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_00186 0.0 mtlR K Mga helix-turn-helix domain
HDBIHKAD_00187 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_00188 7.4e-277 pipD E Dipeptidase
HDBIHKAD_00189 4.8e-99 K Helix-turn-helix domain
HDBIHKAD_00190 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
HDBIHKAD_00191 2.2e-173 P Major Facilitator Superfamily
HDBIHKAD_00192 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HDBIHKAD_00193 4.7e-31 ygzD K Transcriptional
HDBIHKAD_00194 1e-69
HDBIHKAD_00195 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDBIHKAD_00196 1.4e-158 dkgB S reductase
HDBIHKAD_00197 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HDBIHKAD_00198 3.1e-101 S ABC transporter permease
HDBIHKAD_00199 5.3e-259 P ABC transporter
HDBIHKAD_00200 3.1e-116 P cobalt transport
HDBIHKAD_00201 3.9e-38 S ATPases associated with a variety of cellular activities
HDBIHKAD_00202 6.5e-79 L Integrase core domain
HDBIHKAD_00203 4.2e-145 glpQ 3.1.4.46 C phosphodiesterase
HDBIHKAD_00204 1.7e-22 S Family of unknown function (DUF5388)
HDBIHKAD_00205 8.1e-119 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HDBIHKAD_00206 8.3e-162 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HDBIHKAD_00207 8.4e-57 D Alpha beta
HDBIHKAD_00208 2.5e-129 3.4.13.21 E Belongs to the peptidase S51 family
HDBIHKAD_00209 1.3e-91
HDBIHKAD_00210 1.9e-23 S Small integral membrane protein (DUF2273)
HDBIHKAD_00211 7e-141
HDBIHKAD_00212 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
HDBIHKAD_00213 2.3e-82
HDBIHKAD_00214 4.4e-40
HDBIHKAD_00215 1.9e-23 S Small integral membrane protein (DUF2273)
HDBIHKAD_00216 1.6e-73 S cog cog1302
HDBIHKAD_00217 1.3e-11 S Transglycosylase associated protein
HDBIHKAD_00218 4.2e-15
HDBIHKAD_00219 1.7e-43 ankB S ankyrin repeats
HDBIHKAD_00220 2.1e-31
HDBIHKAD_00221 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HDBIHKAD_00222 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HDBIHKAD_00223 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
HDBIHKAD_00224 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDBIHKAD_00225 1.1e-184 S DUF218 domain
HDBIHKAD_00226 3.2e-74
HDBIHKAD_00227 1.1e-29
HDBIHKAD_00228 2.9e-148 yxeH S hydrolase
HDBIHKAD_00229 2.6e-263 ywfO S HD domain protein
HDBIHKAD_00230 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HDBIHKAD_00231 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HDBIHKAD_00232 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HDBIHKAD_00233 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HDBIHKAD_00234 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDBIHKAD_00235 1.2e-228 tdcC E amino acid
HDBIHKAD_00236 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HDBIHKAD_00237 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HDBIHKAD_00238 6.4e-131 S YheO-like PAS domain
HDBIHKAD_00239 2.5e-26
HDBIHKAD_00240 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDBIHKAD_00241 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HDBIHKAD_00242 7.8e-41 rpmE2 J Ribosomal protein L31
HDBIHKAD_00243 3.2e-214 J translation release factor activity
HDBIHKAD_00244 9.2e-127 srtA 3.4.22.70 M sortase family
HDBIHKAD_00245 1.7e-91 lemA S LemA family
HDBIHKAD_00246 4.6e-139 htpX O Belongs to the peptidase M48B family
HDBIHKAD_00247 2e-146
HDBIHKAD_00248 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HDBIHKAD_00249 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HDBIHKAD_00250 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HDBIHKAD_00251 2.1e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HDBIHKAD_00252 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
HDBIHKAD_00253 0.0 kup P Transport of potassium into the cell
HDBIHKAD_00254 2.9e-193 P ABC transporter, substratebinding protein
HDBIHKAD_00255 1.1e-128 ssuC2 U Binding-protein-dependent transport system inner membrane component
HDBIHKAD_00256 1.9e-133 P ATPases associated with a variety of cellular activities
HDBIHKAD_00257 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDBIHKAD_00258 2.2e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDBIHKAD_00259 3.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HDBIHKAD_00260 2.6e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HDBIHKAD_00261 2.3e-90 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HDBIHKAD_00262 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HDBIHKAD_00263 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HDBIHKAD_00264 4.1e-84 S QueT transporter
HDBIHKAD_00265 6.2e-114 S (CBS) domain
HDBIHKAD_00266 1.2e-263 S Putative peptidoglycan binding domain
HDBIHKAD_00267 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDBIHKAD_00268 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HDBIHKAD_00269 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HDBIHKAD_00270 5.5e-284 yabM S Polysaccharide biosynthesis protein
HDBIHKAD_00271 2.2e-42 yabO J S4 domain protein
HDBIHKAD_00273 1.1e-63 divIC D Septum formation initiator
HDBIHKAD_00274 3.1e-74 yabR J RNA binding
HDBIHKAD_00275 1.1e-253 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HDBIHKAD_00276 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HDBIHKAD_00277 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HDBIHKAD_00278 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HDBIHKAD_00279 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDBIHKAD_00280 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HDBIHKAD_00281 2.1e-244 cycA E Amino acid permease
HDBIHKAD_00282 1.5e-167 L PFAM Integrase catalytic region
HDBIHKAD_00283 7.3e-37 M Glycosyltransferase like family 2
HDBIHKAD_00284 2.3e-151 IQ Enoyl-(Acyl carrier protein) reductase
HDBIHKAD_00285 1.1e-138 S Oxidoreductase family, NAD-binding Rossmann fold
HDBIHKAD_00286 2.2e-17 L Helix-turn-helix domain
HDBIHKAD_00287 6.1e-196 tra L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_00288 2.2e-64 GT2,GT4 M Glycosyltransferase GT-D fold
HDBIHKAD_00289 6.1e-196 L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_00290 4.2e-70 S Pyrimidine dimer DNA glycosylase
HDBIHKAD_00291 5.2e-117 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HDBIHKAD_00292 5.1e-129 S WxL domain surface cell wall-binding
HDBIHKAD_00293 5.8e-186 S Bacterial protein of unknown function (DUF916)
HDBIHKAD_00294 0.0
HDBIHKAD_00295 6e-161 ypuA S Protein of unknown function (DUF1002)
HDBIHKAD_00296 5.5e-50 yvlA
HDBIHKAD_00297 1.2e-95 K transcriptional regulator
HDBIHKAD_00298 2.7e-91 ymdB S Macro domain protein
HDBIHKAD_00299 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HDBIHKAD_00300 2.3e-43 S Protein of unknown function (DUF1093)
HDBIHKAD_00301 7.5e-77 S Threonine/Serine exporter, ThrE
HDBIHKAD_00302 9.2e-133 thrE S Putative threonine/serine exporter
HDBIHKAD_00303 5.2e-164 yvgN C Aldo keto reductase
HDBIHKAD_00304 8.4e-152 ywkB S Membrane transport protein
HDBIHKAD_00305 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HDBIHKAD_00306 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HDBIHKAD_00307 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HDBIHKAD_00308 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
HDBIHKAD_00309 6.8e-181 D Alpha beta
HDBIHKAD_00310 8.9e-210 mdtG EGP Major facilitator Superfamily
HDBIHKAD_00311 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
HDBIHKAD_00312 1.6e-64 ycgX S Protein of unknown function (DUF1398)
HDBIHKAD_00313 4.2e-49
HDBIHKAD_00314 3.4e-25
HDBIHKAD_00315 1.5e-248 lmrB EGP Major facilitator Superfamily
HDBIHKAD_00316 7.7e-73 S COG NOG18757 non supervised orthologous group
HDBIHKAD_00317 7.4e-40
HDBIHKAD_00318 4.7e-73 copR K Copper transport repressor CopY TcrY
HDBIHKAD_00319 0.0 copB 3.6.3.4 P P-type ATPase
HDBIHKAD_00320 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HDBIHKAD_00321 6.8e-111 S VIT family
HDBIHKAD_00322 1.8e-119 S membrane
HDBIHKAD_00323 5.9e-158 EG EamA-like transporter family
HDBIHKAD_00324 1.3e-81 elaA S GNAT family
HDBIHKAD_00325 1.1e-115 GM NmrA-like family
HDBIHKAD_00326 2.1e-14
HDBIHKAD_00327 5.9e-55
HDBIHKAD_00328 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HDBIHKAD_00329 4.3e-86
HDBIHKAD_00330 1.9e-62
HDBIHKAD_00331 4.1e-214 mutY L A G-specific adenine glycosylase
HDBIHKAD_00332 4e-53
HDBIHKAD_00333 1.7e-66 yeaO S Protein of unknown function, DUF488
HDBIHKAD_00334 7e-71 spx4 1.20.4.1 P ArsC family
HDBIHKAD_00335 5.4e-66 K Winged helix DNA-binding domain
HDBIHKAD_00336 7.7e-160 azoB GM NmrA-like family
HDBIHKAD_00337 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HDBIHKAD_00338 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_00339 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_00340 4.4e-250 cycA E Amino acid permease
HDBIHKAD_00341 3.4e-253 nhaC C Na H antiporter NhaC
HDBIHKAD_00342 3e-26 3.2.2.10 S Belongs to the LOG family
HDBIHKAD_00343 2.2e-199 frlB M SIS domain
HDBIHKAD_00344 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HDBIHKAD_00345 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
HDBIHKAD_00346 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
HDBIHKAD_00347 1.8e-124 yyaQ S YjbR
HDBIHKAD_00349 0.0 cadA P P-type ATPase
HDBIHKAD_00350 2e-305 U Belongs to the BCCT transporter (TC 2.A.15) family
HDBIHKAD_00351 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
HDBIHKAD_00352 1.4e-77
HDBIHKAD_00353 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HDBIHKAD_00354 3.3e-97 FG HIT domain
HDBIHKAD_00355 1.7e-173 S Aldo keto reductase
HDBIHKAD_00356 1.9e-52 yitW S Pfam:DUF59
HDBIHKAD_00357 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDBIHKAD_00358 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HDBIHKAD_00359 5e-195 blaA6 V Beta-lactamase
HDBIHKAD_00360 6.2e-96 V VanZ like family
HDBIHKAD_00361 8.9e-50 repA S Replication initiator protein A
HDBIHKAD_00362 3.8e-53
HDBIHKAD_00363 3.9e-140 glf 5.4.99.9 M UDP-galactopyranose mutase
HDBIHKAD_00365 2.3e-150
HDBIHKAD_00368 2.7e-31 L Transposase
HDBIHKAD_00369 8.2e-58
HDBIHKAD_00370 2.8e-36 EGP Major facilitator Superfamily
HDBIHKAD_00371 1.5e-106 KLT Protein tyrosine kinase
HDBIHKAD_00374 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
HDBIHKAD_00375 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HDBIHKAD_00376 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HDBIHKAD_00377 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDBIHKAD_00378 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HDBIHKAD_00379 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDBIHKAD_00380 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HDBIHKAD_00381 4.4e-198 pbpX2 V Beta-lactamase
HDBIHKAD_00382 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HDBIHKAD_00383 0.0 dnaK O Heat shock 70 kDa protein
HDBIHKAD_00384 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HDBIHKAD_00385 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HDBIHKAD_00386 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HDBIHKAD_00387 2.7e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDBIHKAD_00388 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HDBIHKAD_00389 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HDBIHKAD_00390 2.1e-194 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HDBIHKAD_00391 4.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HDBIHKAD_00392 8.5e-93
HDBIHKAD_00393 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HDBIHKAD_00394 6.7e-265 ydiN 5.4.99.5 G Major Facilitator
HDBIHKAD_00395 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HDBIHKAD_00396 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HDBIHKAD_00397 3.1e-47 ylxQ J ribosomal protein
HDBIHKAD_00398 9.5e-49 ylxR K Protein of unknown function (DUF448)
HDBIHKAD_00399 3.3e-217 nusA K Participates in both transcription termination and antitermination
HDBIHKAD_00400 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HDBIHKAD_00401 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDBIHKAD_00402 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HDBIHKAD_00403 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HDBIHKAD_00404 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HDBIHKAD_00405 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HDBIHKAD_00406 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HDBIHKAD_00407 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HDBIHKAD_00408 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HDBIHKAD_00409 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HDBIHKAD_00410 4.7e-134 S Haloacid dehalogenase-like hydrolase
HDBIHKAD_00411 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDBIHKAD_00412 3.5e-38 yazA L GIY-YIG catalytic domain protein
HDBIHKAD_00413 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
HDBIHKAD_00414 6.4e-119 plsC 2.3.1.51 I Acyltransferase
HDBIHKAD_00415 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HDBIHKAD_00416 2.9e-36 ynzC S UPF0291 protein
HDBIHKAD_00417 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HDBIHKAD_00418 3.7e-87
HDBIHKAD_00419 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HDBIHKAD_00420 4.6e-75
HDBIHKAD_00421 3e-66
HDBIHKAD_00422 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HDBIHKAD_00423 9.2e-101 L Helix-turn-helix domain
HDBIHKAD_00424 2e-219 lytR5 K Cell envelope-related transcriptional attenuator domain
HDBIHKAD_00425 7.9e-143 P ATPases associated with a variety of cellular activities
HDBIHKAD_00426 9.8e-106 opuAB P Binding-protein-dependent transport system inner membrane component
HDBIHKAD_00429 7.2e-100 tnp L DDE domain
HDBIHKAD_00430 7.6e-92 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDBIHKAD_00432 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
HDBIHKAD_00433 1.2e-103
HDBIHKAD_00434 1.1e-172
HDBIHKAD_00435 0.0 typA T GTP-binding protein TypA
HDBIHKAD_00436 3.5e-135 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HDBIHKAD_00437 3.3e-46 yktA S Belongs to the UPF0223 family
HDBIHKAD_00438 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
HDBIHKAD_00439 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
HDBIHKAD_00440 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HDBIHKAD_00441 1.4e-178 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HDBIHKAD_00442 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HDBIHKAD_00443 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HDBIHKAD_00444 1.6e-85
HDBIHKAD_00445 3.1e-33 ykzG S Belongs to the UPF0356 family
HDBIHKAD_00446 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDBIHKAD_00447 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HDBIHKAD_00448 1.7e-28
HDBIHKAD_00449 2.6e-107 mltD CBM50 M NlpC P60 family protein
HDBIHKAD_00450 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HDBIHKAD_00451 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HDBIHKAD_00452 1.6e-120 S Repeat protein
HDBIHKAD_00453 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HDBIHKAD_00454 5.5e-267 N domain, Protein
HDBIHKAD_00455 1.9e-192 S Bacterial protein of unknown function (DUF916)
HDBIHKAD_00456 2.3e-120 N WxL domain surface cell wall-binding
HDBIHKAD_00457 2.6e-115 ktrA P domain protein
HDBIHKAD_00458 1.3e-241 ktrB P Potassium uptake protein
HDBIHKAD_00459 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HDBIHKAD_00460 4.9e-57 XK27_04120 S Putative amino acid metabolism
HDBIHKAD_00461 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
HDBIHKAD_00462 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HDBIHKAD_00463 4.6e-28
HDBIHKAD_00464 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HDBIHKAD_00465 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HDBIHKAD_00466 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HDBIHKAD_00467 1.2e-86 divIVA D DivIVA domain protein
HDBIHKAD_00468 3.4e-146 ylmH S S4 domain protein
HDBIHKAD_00469 1.2e-36 yggT S YGGT family
HDBIHKAD_00470 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HDBIHKAD_00471 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HDBIHKAD_00472 2.1e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HDBIHKAD_00473 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HDBIHKAD_00474 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HDBIHKAD_00475 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HDBIHKAD_00476 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HDBIHKAD_00477 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HDBIHKAD_00478 7.5e-54 ftsL D Cell division protein FtsL
HDBIHKAD_00479 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HDBIHKAD_00480 1.9e-77 mraZ K Belongs to the MraZ family
HDBIHKAD_00481 1.9e-62 S Protein of unknown function (DUF3397)
HDBIHKAD_00482 1.6e-174 corA P CorA-like Mg2+ transporter protein
HDBIHKAD_00483 1.3e-78 L PFAM Integrase catalytic region
HDBIHKAD_00484 9.7e-205 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_00485 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HDBIHKAD_00486 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDBIHKAD_00487 0.0 oatA I Acyltransferase
HDBIHKAD_00488 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HDBIHKAD_00489 1.1e-68 O OsmC-like protein
HDBIHKAD_00490 2.6e-46
HDBIHKAD_00491 1.1e-251 yfnA E Amino Acid
HDBIHKAD_00492 2.5e-88
HDBIHKAD_00493 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HDBIHKAD_00494 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HDBIHKAD_00495 1.8e-19
HDBIHKAD_00496 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
HDBIHKAD_00497 1.3e-81 zur P Belongs to the Fur family
HDBIHKAD_00498 7.1e-12 3.2.1.14 GH18
HDBIHKAD_00499 4.9e-148
HDBIHKAD_00500 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HDBIHKAD_00501 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HDBIHKAD_00502 8e-169 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDBIHKAD_00503 8.9e-40
HDBIHKAD_00505 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_00506 7.8e-149 glnH ET ABC transporter substrate-binding protein
HDBIHKAD_00507 3.5e-109 gluC P ABC transporter permease
HDBIHKAD_00508 4e-108 glnP P ABC transporter permease
HDBIHKAD_00509 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDBIHKAD_00510 1.4e-153 K CAT RNA binding domain
HDBIHKAD_00511 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HDBIHKAD_00512 6.1e-140 G YdjC-like protein
HDBIHKAD_00513 8.3e-246 steT E amino acid
HDBIHKAD_00514 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_00515 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HDBIHKAD_00516 2.8e-70 K MarR family
HDBIHKAD_00517 4.9e-210 EGP Major facilitator Superfamily
HDBIHKAD_00518 3.8e-85 S membrane transporter protein
HDBIHKAD_00519 7.1e-98 K Bacterial regulatory proteins, tetR family
HDBIHKAD_00520 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HDBIHKAD_00521 2.9e-78 3.6.1.55 F NUDIX domain
HDBIHKAD_00522 1.3e-48 sugE U Multidrug resistance protein
HDBIHKAD_00523 1.2e-26
HDBIHKAD_00524 5.5e-129 pgm3 G Phosphoglycerate mutase family
HDBIHKAD_00525 4.7e-125 pgm3 G Phosphoglycerate mutase family
HDBIHKAD_00526 0.0 yjbQ P TrkA C-terminal domain protein
HDBIHKAD_00527 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HDBIHKAD_00528 7.2e-110 dedA S SNARE associated Golgi protein
HDBIHKAD_00529 0.0 helD 3.6.4.12 L DNA helicase
HDBIHKAD_00530 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
HDBIHKAD_00531 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HDBIHKAD_00532 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HDBIHKAD_00534 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
HDBIHKAD_00536 7.6e-46 L Helix-turn-helix domain
HDBIHKAD_00537 6.9e-29 L hmm pf00665
HDBIHKAD_00538 8.9e-23 L hmm pf00665
HDBIHKAD_00539 5.7e-46
HDBIHKAD_00540 7.5e-86 KLT Protein tyrosine kinase
HDBIHKAD_00541 2.9e-23 S Protein of unknown function (DUF4064)
HDBIHKAD_00542 6e-97 S Domain of unknown function (DUF4352)
HDBIHKAD_00543 3.9e-75 S Psort location Cytoplasmic, score
HDBIHKAD_00544 4.8e-55
HDBIHKAD_00545 3.6e-110 S membrane transporter protein
HDBIHKAD_00546 2.3e-54 azlD S branched-chain amino acid
HDBIHKAD_00547 5.1e-131 azlC E branched-chain amino acid
HDBIHKAD_00548 6.4e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HDBIHKAD_00549 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDBIHKAD_00550 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HDBIHKAD_00551 3.2e-124 K response regulator
HDBIHKAD_00552 5.5e-124 yoaK S Protein of unknown function (DUF1275)
HDBIHKAD_00553 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDBIHKAD_00554 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDBIHKAD_00555 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HDBIHKAD_00556 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HDBIHKAD_00557 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HDBIHKAD_00558 2.4e-156 spo0J K Belongs to the ParB family
HDBIHKAD_00559 1.8e-136 soj D Sporulation initiation inhibitor
HDBIHKAD_00560 7.9e-149 noc K Belongs to the ParB family
HDBIHKAD_00561 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HDBIHKAD_00562 1.2e-225 nupG F Nucleoside
HDBIHKAD_00563 0.0 S Bacterial membrane protein YfhO
HDBIHKAD_00564 3.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_00565 2.1e-168 K LysR substrate binding domain
HDBIHKAD_00566 1.9e-236 EK Aminotransferase, class I
HDBIHKAD_00567 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HDBIHKAD_00568 8.1e-123 tcyB E ABC transporter
HDBIHKAD_00569 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_00570 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HDBIHKAD_00571 5.8e-79 KT response to antibiotic
HDBIHKAD_00572 9.8e-52 K Transcriptional regulator
HDBIHKAD_00573 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HDBIHKAD_00574 2.1e-126 S Putative adhesin
HDBIHKAD_00575 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HDBIHKAD_00576 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDBIHKAD_00577 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HDBIHKAD_00578 2.6e-205 S DUF218 domain
HDBIHKAD_00579 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
HDBIHKAD_00580 6.8e-116 ybbL S ABC transporter, ATP-binding protein
HDBIHKAD_00581 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDBIHKAD_00582 9.4e-77
HDBIHKAD_00583 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
HDBIHKAD_00584 1.1e-147 cof S haloacid dehalogenase-like hydrolase
HDBIHKAD_00585 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HDBIHKAD_00586 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HDBIHKAD_00587 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
HDBIHKAD_00588 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_00589 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HDBIHKAD_00590 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDBIHKAD_00591 1.2e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HDBIHKAD_00592 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HDBIHKAD_00593 1.3e-128 K Helix-turn-helix domain, rpiR family
HDBIHKAD_00594 8.5e-159 S Alpha beta hydrolase
HDBIHKAD_00595 9.9e-112 GM NmrA-like family
HDBIHKAD_00596 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
HDBIHKAD_00597 1.9e-161 K Transcriptional regulator
HDBIHKAD_00598 1.9e-172 C nadph quinone reductase
HDBIHKAD_00599 6.3e-14 S Alpha beta hydrolase
HDBIHKAD_00600 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDBIHKAD_00601 4e-102 desR K helix_turn_helix, Lux Regulon
HDBIHKAD_00602 2.8e-207 desK 2.7.13.3 T Histidine kinase
HDBIHKAD_00603 3.1e-136 yvfS V ABC-2 type transporter
HDBIHKAD_00604 5.2e-159 yvfR V ABC transporter
HDBIHKAD_00606 6e-82 K Acetyltransferase (GNAT) domain
HDBIHKAD_00607 2.4e-72 K MarR family
HDBIHKAD_00608 3.8e-114 S Psort location CytoplasmicMembrane, score
HDBIHKAD_00609 2.6e-12 yjdF S Protein of unknown function (DUF2992)
HDBIHKAD_00610 5.6e-161 V ABC transporter, ATP-binding protein
HDBIHKAD_00611 5.2e-128 S ABC-2 family transporter protein
HDBIHKAD_00612 1.5e-197
HDBIHKAD_00613 5.9e-202
HDBIHKAD_00614 4.8e-165 ytrB V ABC transporter, ATP-binding protein
HDBIHKAD_00615 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
HDBIHKAD_00616 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HDBIHKAD_00617 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HDBIHKAD_00618 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HDBIHKAD_00619 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HDBIHKAD_00620 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
HDBIHKAD_00621 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HDBIHKAD_00622 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HDBIHKAD_00623 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HDBIHKAD_00624 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
HDBIHKAD_00625 2.6e-71 yqeY S YqeY-like protein
HDBIHKAD_00626 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HDBIHKAD_00627 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HDBIHKAD_00628 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
HDBIHKAD_00629 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HDBIHKAD_00630 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDBIHKAD_00631 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDBIHKAD_00632 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDBIHKAD_00633 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HDBIHKAD_00634 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HDBIHKAD_00635 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HDBIHKAD_00636 1.6e-160 yniA G Fructosamine kinase
HDBIHKAD_00637 6.5e-116 3.1.3.18 J HAD-hyrolase-like
HDBIHKAD_00638 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HDBIHKAD_00639 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HDBIHKAD_00640 9.6e-58
HDBIHKAD_00641 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HDBIHKAD_00642 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HDBIHKAD_00643 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HDBIHKAD_00644 1.4e-49
HDBIHKAD_00645 1.4e-49
HDBIHKAD_00646 3.8e-63 S Domain of unknown function (DUF4440)
HDBIHKAD_00647 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
HDBIHKAD_00648 8.2e-48
HDBIHKAD_00649 3.2e-37
HDBIHKAD_00650 2.8e-85 yvbK 3.1.3.25 K GNAT family
HDBIHKAD_00651 3.8e-84
HDBIHKAD_00653 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDBIHKAD_00654 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDBIHKAD_00655 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HDBIHKAD_00657 7.5e-121 macB V ABC transporter, ATP-binding protein
HDBIHKAD_00658 0.0 ylbB V ABC transporter permease
HDBIHKAD_00659 4.8e-235 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDBIHKAD_00660 9.8e-79 K transcriptional regulator, MerR family
HDBIHKAD_00661 3.2e-76 yphH S Cupin domain
HDBIHKAD_00662 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HDBIHKAD_00663 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDBIHKAD_00664 4.7e-211 natB CP ABC-2 family transporter protein
HDBIHKAD_00665 7.5e-166 natA S ABC transporter, ATP-binding protein
HDBIHKAD_00666 1.2e-91 ogt 2.1.1.63 L Methyltransferase
HDBIHKAD_00667 5.6e-51 lytE M LysM domain
HDBIHKAD_00668 1.6e-33 lytE M LysM domain protein
HDBIHKAD_00669 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_00670 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HDBIHKAD_00671 4.8e-151 rlrG K Transcriptional regulator
HDBIHKAD_00672 9.3e-173 S Conserved hypothetical protein 698
HDBIHKAD_00673 1.8e-101 rimL J Acetyltransferase (GNAT) domain
HDBIHKAD_00674 2e-75 S Domain of unknown function (DUF4811)
HDBIHKAD_00675 4.1e-270 lmrB EGP Major facilitator Superfamily
HDBIHKAD_00676 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDBIHKAD_00677 1.5e-177 ynfM EGP Major facilitator Superfamily
HDBIHKAD_00678 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HDBIHKAD_00679 1.2e-155 mleP3 S Membrane transport protein
HDBIHKAD_00680 6.4e-117 S Membrane
HDBIHKAD_00681 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDBIHKAD_00682 8.1e-99 1.5.1.3 H RibD C-terminal domain
HDBIHKAD_00683 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HDBIHKAD_00684 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HDBIHKAD_00685 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HDBIHKAD_00686 5.2e-174 hrtB V ABC transporter permease
HDBIHKAD_00687 6.6e-95 S Protein of unknown function (DUF1440)
HDBIHKAD_00688 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HDBIHKAD_00689 6.4e-148 KT helix_turn_helix, mercury resistance
HDBIHKAD_00690 1.6e-115 S Protein of unknown function (DUF554)
HDBIHKAD_00691 1.1e-92 yueI S Protein of unknown function (DUF1694)
HDBIHKAD_00692 2e-143 yvpB S Peptidase_C39 like family
HDBIHKAD_00693 9.3e-149 M Glycosyl hydrolases family 25
HDBIHKAD_00694 3.9e-111
HDBIHKAD_00695 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HDBIHKAD_00696 1.8e-84 hmpT S Pfam:DUF3816
HDBIHKAD_00697 5.9e-239 L Transposase
HDBIHKAD_00698 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HDBIHKAD_00699 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HDBIHKAD_00700 2.7e-154 ymdB S YmdB-like protein
HDBIHKAD_00701 4.7e-216 rny S Endoribonuclease that initiates mRNA decay
HDBIHKAD_00702 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HDBIHKAD_00703 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
HDBIHKAD_00704 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HDBIHKAD_00705 5.7e-110 ymfM S Helix-turn-helix domain
HDBIHKAD_00706 2.9e-251 ymfH S Peptidase M16
HDBIHKAD_00707 1.9e-231 ymfF S Peptidase M16 inactive domain protein
HDBIHKAD_00708 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HDBIHKAD_00709 5.6e-155 aatB ET ABC transporter substrate-binding protein
HDBIHKAD_00710 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_00711 4.6e-109 glnP P ABC transporter permease
HDBIHKAD_00712 1.2e-146 minD D Belongs to the ParA family
HDBIHKAD_00713 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HDBIHKAD_00714 1.2e-88 mreD M rod shape-determining protein MreD
HDBIHKAD_00715 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HDBIHKAD_00716 2.8e-161 mreB D cell shape determining protein MreB
HDBIHKAD_00717 1.3e-116 radC L DNA repair protein
HDBIHKAD_00718 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDBIHKAD_00719 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HDBIHKAD_00720 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HDBIHKAD_00721 6.8e-234 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HDBIHKAD_00722 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HDBIHKAD_00723 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
HDBIHKAD_00724 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HDBIHKAD_00725 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
HDBIHKAD_00726 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HDBIHKAD_00727 5.2e-113 yktB S Belongs to the UPF0637 family
HDBIHKAD_00728 7.3e-80 yueI S Protein of unknown function (DUF1694)
HDBIHKAD_00729 2e-109 S Protein of unknown function (DUF1648)
HDBIHKAD_00730 1.9e-43 czrA K Helix-turn-helix domain
HDBIHKAD_00731 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HDBIHKAD_00732 8e-238 rarA L recombination factor protein RarA
HDBIHKAD_00733 1.5e-38
HDBIHKAD_00734 6.2e-82 usp6 T universal stress protein
HDBIHKAD_00735 1.5e-200 bla2 3.5.2.6 V Beta-lactamase enzyme family
HDBIHKAD_00736 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_00737 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HDBIHKAD_00738 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HDBIHKAD_00739 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDBIHKAD_00740 1.6e-177 S Protein of unknown function (DUF2785)
HDBIHKAD_00741 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HDBIHKAD_00742 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
HDBIHKAD_00743 1.4e-111 metI U ABC transporter permease
HDBIHKAD_00744 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDBIHKAD_00745 3.6e-48 gcsH2 E glycine cleavage
HDBIHKAD_00746 9.3e-220 rodA D Belongs to the SEDS family
HDBIHKAD_00747 1.2e-32 S Protein of unknown function (DUF2969)
HDBIHKAD_00748 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HDBIHKAD_00749 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HDBIHKAD_00750 2.1e-102 J Acetyltransferase (GNAT) domain
HDBIHKAD_00751 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HDBIHKAD_00752 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HDBIHKAD_00753 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HDBIHKAD_00754 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HDBIHKAD_00755 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HDBIHKAD_00756 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDBIHKAD_00757 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HDBIHKAD_00758 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HDBIHKAD_00759 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HDBIHKAD_00760 1e-232 pyrP F Permease
HDBIHKAD_00761 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HDBIHKAD_00762 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HDBIHKAD_00763 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HDBIHKAD_00764 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HDBIHKAD_00765 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HDBIHKAD_00766 1.2e-108 tdk 2.7.1.21 F thymidine kinase
HDBIHKAD_00767 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HDBIHKAD_00768 6.5e-136 cobQ S glutamine amidotransferase
HDBIHKAD_00769 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
HDBIHKAD_00770 1.2e-191 ampC V Beta-lactamase
HDBIHKAD_00771 5.2e-29
HDBIHKAD_00772 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HDBIHKAD_00773 1.9e-58
HDBIHKAD_00774 2.8e-126
HDBIHKAD_00775 0.0 yfiC V ABC transporter
HDBIHKAD_00776 9.6e-311 ycfI V ABC transporter, ATP-binding protein
HDBIHKAD_00777 3.3e-65 S Protein of unknown function (DUF1093)
HDBIHKAD_00778 1.3e-132 yxkH G Polysaccharide deacetylase
HDBIHKAD_00780 3.3e-61 V Abortive infection bacteriophage resistance protein
HDBIHKAD_00781 3e-23 hol S Bacteriophage holin
HDBIHKAD_00782 4.7e-48
HDBIHKAD_00783 3.9e-180 M hydrolase, family 25
HDBIHKAD_00786 1.7e-82 S Calcineurin-like phosphoesterase
HDBIHKAD_00789 6.9e-100 S Prophage endopeptidase tail
HDBIHKAD_00790 7.6e-48 S Phage tail protein
HDBIHKAD_00791 2.3e-111 S peptidoglycan catabolic process
HDBIHKAD_00792 2.1e-13 S Bacteriophage Gp15 protein
HDBIHKAD_00794 6.4e-39 N domain, Protein
HDBIHKAD_00795 8.6e-11 S Minor capsid protein from bacteriophage
HDBIHKAD_00798 7.9e-14
HDBIHKAD_00799 3.5e-07
HDBIHKAD_00800 6.9e-109
HDBIHKAD_00802 3.4e-46 S Phage minor capsid protein 2
HDBIHKAD_00803 8.8e-114 S Phage portal protein, SPP1 Gp6-like
HDBIHKAD_00804 9.3e-189 S Phage terminase, large subunit, PBSX family
HDBIHKAD_00805 3.4e-47 S Terminase small subunit
HDBIHKAD_00807 1.5e-42
HDBIHKAD_00811 2e-16 S KTSC domain
HDBIHKAD_00814 6.5e-81 arpU S Phage transcriptional regulator, ArpU family
HDBIHKAD_00815 4.6e-30
HDBIHKAD_00816 4.5e-38 S YopX protein
HDBIHKAD_00817 2.4e-65 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDBIHKAD_00818 1.3e-85
HDBIHKAD_00819 2.2e-50
HDBIHKAD_00820 5.1e-165 L Domain of unknown function (DUF4373)
HDBIHKAD_00821 1.4e-64
HDBIHKAD_00822 1.6e-54 S Bacteriophage Mu Gam like protein
HDBIHKAD_00825 9.5e-81
HDBIHKAD_00826 7e-55
HDBIHKAD_00829 3.4e-40 yvaO K Helix-turn-helix domain
HDBIHKAD_00830 3.3e-76 E IrrE N-terminal-like domain
HDBIHKAD_00831 5.5e-53
HDBIHKAD_00832 2.8e-11 M LysM domain
HDBIHKAD_00834 1.6e-24 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDBIHKAD_00835 1.2e-26
HDBIHKAD_00836 3.3e-35 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HDBIHKAD_00839 1.6e-37
HDBIHKAD_00841 2.8e-218 int L Belongs to the 'phage' integrase family
HDBIHKAD_00843 8.9e-30
HDBIHKAD_00846 2.3e-55
HDBIHKAD_00847 2.3e-38 S Phage gp6-like head-tail connector protein
HDBIHKAD_00848 1.5e-278 S Caudovirus prohead serine protease
HDBIHKAD_00849 5e-204 S Phage portal protein
HDBIHKAD_00851 0.0 terL S overlaps another CDS with the same product name
HDBIHKAD_00852 1.6e-82 terS L overlaps another CDS with the same product name
HDBIHKAD_00853 7.7e-67 L HNH endonuclease
HDBIHKAD_00854 3.1e-48 S head-tail joining protein
HDBIHKAD_00856 7e-74
HDBIHKAD_00857 1.6e-263 S Virulence-associated protein E
HDBIHKAD_00858 5.9e-146 L DNA replication protein
HDBIHKAD_00860 8.7e-34
HDBIHKAD_00861 6.6e-08
HDBIHKAD_00864 1.7e-15 K Cro/C1-type HTH DNA-binding domain
HDBIHKAD_00865 2.1e-224 sip L Belongs to the 'phage' integrase family
HDBIHKAD_00866 2e-38
HDBIHKAD_00867 1.4e-43
HDBIHKAD_00868 7.3e-83 K MarR family
HDBIHKAD_00869 0.0 bztC D nuclear chromosome segregation
HDBIHKAD_00870 2.5e-108 M MucBP domain
HDBIHKAD_00871 3.8e-93 M MucBP domain
HDBIHKAD_00872 1.5e-14
HDBIHKAD_00873 4.7e-16
HDBIHKAD_00874 1.5e-14
HDBIHKAD_00875 5.5e-18
HDBIHKAD_00876 1.6e-16
HDBIHKAD_00877 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HDBIHKAD_00878 8.6e-274 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_00879 0.0 macB3 V ABC transporter, ATP-binding protein
HDBIHKAD_00880 6.8e-24
HDBIHKAD_00881 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
HDBIHKAD_00882 9.7e-155 glcU U sugar transport
HDBIHKAD_00883 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HDBIHKAD_00884 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HDBIHKAD_00885 1.6e-134 K response regulator
HDBIHKAD_00886 3e-243 XK27_08635 S UPF0210 protein
HDBIHKAD_00887 2.3e-38 gcvR T Belongs to the UPF0237 family
HDBIHKAD_00888 2.6e-169 EG EamA-like transporter family
HDBIHKAD_00890 1.3e-46
HDBIHKAD_00891 6.9e-27
HDBIHKAD_00892 1.5e-60
HDBIHKAD_00893 2.1e-263 S Virulence-associated protein E
HDBIHKAD_00894 8.3e-137 L Primase C terminal 1 (PriCT-1)
HDBIHKAD_00895 2e-27
HDBIHKAD_00896 1.4e-21
HDBIHKAD_00899 2.5e-40
HDBIHKAD_00900 2.6e-97 S Phage regulatory protein Rha (Phage_pRha)
HDBIHKAD_00902 3.1e-27 K Cro/C1-type HTH DNA-binding domain
HDBIHKAD_00903 1.9e-105 sip L Belongs to the 'phage' integrase family
HDBIHKAD_00904 6.5e-91 S ECF-type riboflavin transporter, S component
HDBIHKAD_00905 4.2e-47
HDBIHKAD_00906 9.8e-214 yceI EGP Major facilitator Superfamily
HDBIHKAD_00907 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HDBIHKAD_00908 3.8e-23
HDBIHKAD_00910 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_00911 3.1e-172 ykfC 3.4.14.13 M NlpC/P60 family
HDBIHKAD_00912 3.3e-80 K AsnC family
HDBIHKAD_00913 2e-35
HDBIHKAD_00914 3.3e-33
HDBIHKAD_00915 5.6e-217 2.7.7.65 T diguanylate cyclase
HDBIHKAD_00916 7.8e-296 S ABC transporter, ATP-binding protein
HDBIHKAD_00917 2e-106 3.2.2.20 K acetyltransferase
HDBIHKAD_00918 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HDBIHKAD_00919 6e-39
HDBIHKAD_00920 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HDBIHKAD_00921 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDBIHKAD_00922 5e-162 degV S Uncharacterised protein, DegV family COG1307
HDBIHKAD_00923 5.1e-66 hom1 1.1.1.3 E Homoserine dehydrogenase
HDBIHKAD_00924 2e-144 hom1 1.1.1.3 E Homoserine dehydrogenase
HDBIHKAD_00925 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HDBIHKAD_00926 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HDBIHKAD_00927 3.1e-176 XK27_08835 S ABC transporter
HDBIHKAD_00928 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HDBIHKAD_00929 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
HDBIHKAD_00930 1.3e-257 npr 1.11.1.1 C NADH oxidase
HDBIHKAD_00931 2.2e-151 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HDBIHKAD_00932 3.1e-136 terC P membrane
HDBIHKAD_00933 3.6e-55 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDBIHKAD_00934 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HDBIHKAD_00935 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HDBIHKAD_00936 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HDBIHKAD_00937 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HDBIHKAD_00938 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HDBIHKAD_00939 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HDBIHKAD_00940 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HDBIHKAD_00941 2.7e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HDBIHKAD_00942 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HDBIHKAD_00943 6.6e-215 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HDBIHKAD_00944 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HDBIHKAD_00945 4.6e-216 ysaA V RDD family
HDBIHKAD_00946 7.6e-166 corA P CorA-like Mg2+ transporter protein
HDBIHKAD_00947 2.1e-55 S Domain of unknown function (DU1801)
HDBIHKAD_00948 5.9e-91 rmeB K transcriptional regulator, MerR family
HDBIHKAD_00949 9.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HDBIHKAD_00950 8.6e-98 J glyoxalase III activity
HDBIHKAD_00951 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HDBIHKAD_00952 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDBIHKAD_00953 3.7e-34
HDBIHKAD_00954 5.1e-103 S Protein of unknown function (DUF1211)
HDBIHKAD_00955 1.6e-138 K LysR substrate binding domain
HDBIHKAD_00956 1.9e-104 GM NAD(P)H-binding
HDBIHKAD_00957 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDBIHKAD_00958 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HDBIHKAD_00959 8.4e-34
HDBIHKAD_00960 6.1e-76 T Belongs to the universal stress protein A family
HDBIHKAD_00961 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HDBIHKAD_00962 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HDBIHKAD_00963 3.9e-58
HDBIHKAD_00964 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HDBIHKAD_00965 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
HDBIHKAD_00966 7.4e-102 M Protein of unknown function (DUF3737)
HDBIHKAD_00967 1.2e-194 C Aldo/keto reductase family
HDBIHKAD_00969 0.0 mdlB V ABC transporter
HDBIHKAD_00970 0.0 mdlA V ABC transporter
HDBIHKAD_00971 1.3e-246 EGP Major facilitator Superfamily
HDBIHKAD_00976 1e-197 yhgE V domain protein
HDBIHKAD_00977 1.5e-95 K Transcriptional regulator (TetR family)
HDBIHKAD_00978 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_00979 1.7e-139 endA F DNA RNA non-specific endonuclease
HDBIHKAD_00980 6.3e-99 speG J Acetyltransferase (GNAT) domain
HDBIHKAD_00981 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HDBIHKAD_00982 1.1e-223 S CAAX protease self-immunity
HDBIHKAD_00983 1.2e-307 ybiT S ABC transporter, ATP-binding protein
HDBIHKAD_00984 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
HDBIHKAD_00985 0.0 S Predicted membrane protein (DUF2207)
HDBIHKAD_00986 0.0 uvrA3 L excinuclease ABC
HDBIHKAD_00987 3.1e-207 EGP Major facilitator Superfamily
HDBIHKAD_00988 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
HDBIHKAD_00989 4.9e-233 yxiO S Vacuole effluxer Atg22 like
HDBIHKAD_00990 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
HDBIHKAD_00991 1.1e-158 I alpha/beta hydrolase fold
HDBIHKAD_00992 7e-130 treR K UTRA
HDBIHKAD_00993 2.5e-235
HDBIHKAD_00994 5.6e-39 S Cytochrome B5
HDBIHKAD_00995 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDBIHKAD_00996 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HDBIHKAD_00997 1.6e-75 yugI 5.3.1.9 J general stress protein
HDBIHKAD_00998 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HDBIHKAD_00999 1.9e-118 dedA S SNARE-like domain protein
HDBIHKAD_01000 1.8e-116 S Protein of unknown function (DUF1461)
HDBIHKAD_01001 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HDBIHKAD_01002 1.5e-80 yutD S Protein of unknown function (DUF1027)
HDBIHKAD_01003 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HDBIHKAD_01004 4.4e-117 S Calcineurin-like phosphoesterase
HDBIHKAD_01005 5.3e-251 cycA E Amino acid permease
HDBIHKAD_01006 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDBIHKAD_01007 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HDBIHKAD_01009 4.5e-88 S Prokaryotic N-terminal methylation motif
HDBIHKAD_01010 8.6e-20
HDBIHKAD_01011 3.2e-83 gspG NU general secretion pathway protein
HDBIHKAD_01012 5.5e-43 comGC U competence protein ComGC
HDBIHKAD_01013 1.9e-189 comGB NU type II secretion system
HDBIHKAD_01014 2.1e-174 comGA NU Type II IV secretion system protein
HDBIHKAD_01015 8.3e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDBIHKAD_01016 8.3e-131 yebC K Transcriptional regulatory protein
HDBIHKAD_01017 1.6e-49 S DsrE/DsrF-like family
HDBIHKAD_01018 2.3e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HDBIHKAD_01019 1.9e-181 ccpA K catabolite control protein A
HDBIHKAD_01020 3.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDBIHKAD_01021 6e-29 K helix_turn_helix, mercury resistance
HDBIHKAD_01022 5.2e-19 K helix_turn_helix, mercury resistance
HDBIHKAD_01023 2.8e-56
HDBIHKAD_01024 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HDBIHKAD_01025 2.6e-158 ykuT M mechanosensitive ion channel
HDBIHKAD_01026 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HDBIHKAD_01027 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HDBIHKAD_01028 6.5e-87 ykuL S (CBS) domain
HDBIHKAD_01029 9.5e-97 S Phosphoesterase
HDBIHKAD_01030 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HDBIHKAD_01031 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HDBIHKAD_01032 2.9e-125 yslB S Protein of unknown function (DUF2507)
HDBIHKAD_01033 3.3e-52 trxA O Belongs to the thioredoxin family
HDBIHKAD_01034 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HDBIHKAD_01035 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HDBIHKAD_01036 1.6e-48 yrzB S Belongs to the UPF0473 family
HDBIHKAD_01037 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HDBIHKAD_01038 2.4e-43 yrzL S Belongs to the UPF0297 family
HDBIHKAD_01039 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HDBIHKAD_01040 2.3e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HDBIHKAD_01041 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HDBIHKAD_01042 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HDBIHKAD_01043 2.8e-29 yajC U Preprotein translocase
HDBIHKAD_01044 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HDBIHKAD_01045 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HDBIHKAD_01046 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HDBIHKAD_01047 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HDBIHKAD_01048 9.6e-89
HDBIHKAD_01049 0.0 S Bacterial membrane protein YfhO
HDBIHKAD_01050 3.1e-71
HDBIHKAD_01051 2.6e-65
HDBIHKAD_01052 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
HDBIHKAD_01053 1.3e-102 K transcriptional regulator
HDBIHKAD_01054 1.4e-181 yfeX P Peroxidase
HDBIHKAD_01055 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HDBIHKAD_01056 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HDBIHKAD_01057 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HDBIHKAD_01058 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HDBIHKAD_01059 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_01060 1.5e-55 txlA O Thioredoxin-like domain
HDBIHKAD_01061 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
HDBIHKAD_01062 1.2e-18
HDBIHKAD_01063 6.6e-96 dps P Belongs to the Dps family
HDBIHKAD_01064 1.6e-32 copZ P Heavy-metal-associated domain
HDBIHKAD_01065 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HDBIHKAD_01066 0.0 pepO 3.4.24.71 O Peptidase family M13
HDBIHKAD_01067 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HDBIHKAD_01068 1.3e-262 nox C NADH oxidase
HDBIHKAD_01069 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HDBIHKAD_01070 1e-163 S Cell surface protein
HDBIHKAD_01071 1.5e-118 S WxL domain surface cell wall-binding
HDBIHKAD_01072 2.3e-99 S WxL domain surface cell wall-binding
HDBIHKAD_01073 4.6e-45
HDBIHKAD_01074 1.7e-102 K Bacterial regulatory proteins, tetR family
HDBIHKAD_01075 1.5e-49
HDBIHKAD_01076 1.4e-248 S Putative metallopeptidase domain
HDBIHKAD_01077 3.9e-218 3.1.3.1 S associated with various cellular activities
HDBIHKAD_01078 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_01079 0.0 ubiB S ABC1 family
HDBIHKAD_01080 1.4e-248 brnQ U Component of the transport system for branched-chain amino acids
HDBIHKAD_01081 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDBIHKAD_01082 2.3e-229 mdtH P Sugar (and other) transporter
HDBIHKAD_01083 1.6e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HDBIHKAD_01084 8.6e-232 EGP Major facilitator Superfamily
HDBIHKAD_01085 1.2e-137 rhaR K helix_turn_helix, arabinose operon control protein
HDBIHKAD_01086 2.1e-38 fic D Fic/DOC family
HDBIHKAD_01087 1.9e-25 fic D Fic/DOC family
HDBIHKAD_01088 2.4e-22 fic D Fic/DOC family
HDBIHKAD_01089 8e-76 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_01090 1.6e-180 galR K Transcriptional regulator
HDBIHKAD_01091 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HDBIHKAD_01092 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDBIHKAD_01093 2.3e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDBIHKAD_01094 2.7e-171 L Belongs to the 'phage' integrase family
HDBIHKAD_01095 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
HDBIHKAD_01096 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HDBIHKAD_01097 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HDBIHKAD_01098 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HDBIHKAD_01100 1e-87 S AAA domain
HDBIHKAD_01101 2.3e-139 K sequence-specific DNA binding
HDBIHKAD_01102 2.3e-96 K Helix-turn-helix domain
HDBIHKAD_01103 2.8e-171 K Transcriptional regulator
HDBIHKAD_01104 1.2e-97 1.3.5.4 C FMN_bind
HDBIHKAD_01105 3.4e-219 1.3.5.4 C FMN_bind
HDBIHKAD_01107 2.3e-81 rmaD K Transcriptional regulator
HDBIHKAD_01108 1.6e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDBIHKAD_01109 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDBIHKAD_01110 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
HDBIHKAD_01111 6.7e-278 pipD E Dipeptidase
HDBIHKAD_01112 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HDBIHKAD_01113 8.5e-41
HDBIHKAD_01114 4.1e-32 L leucine-zipper of insertion element IS481
HDBIHKAD_01115 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDBIHKAD_01116 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HDBIHKAD_01117 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_01118 5.6e-138 S NADPH-dependent FMN reductase
HDBIHKAD_01119 8.6e-179
HDBIHKAD_01120 1.4e-218 yibE S overlaps another CDS with the same product name
HDBIHKAD_01121 3.4e-127 yibF S overlaps another CDS with the same product name
HDBIHKAD_01122 2e-91 3.2.2.20 K FR47-like protein
HDBIHKAD_01123 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HDBIHKAD_01124 5.6e-49
HDBIHKAD_01125 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
HDBIHKAD_01126 1e-254 xylP2 G symporter
HDBIHKAD_01127 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HDBIHKAD_01128 4.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HDBIHKAD_01129 0.0 asnB 6.3.5.4 E Asparagine synthase
HDBIHKAD_01130 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HDBIHKAD_01131 1.4e-67 azlC E branched-chain amino acid
HDBIHKAD_01132 4.4e-35 yyaN K MerR HTH family regulatory protein
HDBIHKAD_01133 1e-106
HDBIHKAD_01134 1.4e-117 S Domain of unknown function (DUF4811)
HDBIHKAD_01135 7.3e-170 lmrB EGP Major facilitator Superfamily
HDBIHKAD_01136 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
HDBIHKAD_01137 1.2e-286
HDBIHKAD_01138 1.6e-205 ftsW D Belongs to the SEDS family
HDBIHKAD_01139 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HDBIHKAD_01140 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HDBIHKAD_01141 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HDBIHKAD_01142 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HDBIHKAD_01143 9.6e-197 ylbL T Belongs to the peptidase S16 family
HDBIHKAD_01144 6.2e-64 comEA L Competence protein ComEA
HDBIHKAD_01145 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HDBIHKAD_01146 0.0 comEC S Competence protein ComEC
HDBIHKAD_01147 2.7e-186 holA 2.7.7.7 L DNA polymerase III delta subunit
HDBIHKAD_01148 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HDBIHKAD_01149 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HDBIHKAD_01150 7.8e-38 L Helix-turn-helix domain
HDBIHKAD_01151 4.3e-109 L Helix-turn-helix domain
HDBIHKAD_01152 2e-190 mdtG EGP Major Facilitator Superfamily
HDBIHKAD_01153 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDBIHKAD_01154 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HDBIHKAD_01155 1e-157 S Tetratricopeptide repeat
HDBIHKAD_01156 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HDBIHKAD_01157 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HDBIHKAD_01158 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HDBIHKAD_01159 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HDBIHKAD_01160 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HDBIHKAD_01161 9.9e-73 S Iron-sulphur cluster biosynthesis
HDBIHKAD_01162 4.3e-22
HDBIHKAD_01163 9.2e-270 glnPH2 P ABC transporter permease
HDBIHKAD_01164 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_01165 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HDBIHKAD_01166 2.9e-126 epsB M biosynthesis protein
HDBIHKAD_01167 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HDBIHKAD_01168 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
HDBIHKAD_01169 2.1e-179 cps4D 5.1.3.2 M RmlD substrate binding domain
HDBIHKAD_01170 7.4e-126 tuaA M Bacterial sugar transferase
HDBIHKAD_01171 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HDBIHKAD_01172 5e-190 cps4G M Glycosyltransferase Family 4
HDBIHKAD_01173 5e-232
HDBIHKAD_01174 3.1e-162 cps4I M Glycosyltransferase like family 2
HDBIHKAD_01175 2e-40 EG EamA-like transporter family
HDBIHKAD_01176 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HDBIHKAD_01177 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDBIHKAD_01178 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HDBIHKAD_01179 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDBIHKAD_01180 4.4e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HDBIHKAD_01181 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HDBIHKAD_01182 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDBIHKAD_01183 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HDBIHKAD_01184 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
HDBIHKAD_01185 0.0 levR K Sigma-54 interaction domain
HDBIHKAD_01186 4.7e-64 S Domain of unknown function (DUF956)
HDBIHKAD_01187 4.4e-169 manN G system, mannose fructose sorbose family IID component
HDBIHKAD_01188 3.4e-133 manY G PTS system
HDBIHKAD_01189 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HDBIHKAD_01190 1.5e-146 G Peptidase_C39 like family
HDBIHKAD_01192 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HDBIHKAD_01193 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HDBIHKAD_01194 9.8e-82 ydcK S Belongs to the SprT family
HDBIHKAD_01195 0.0 yhgF K Tex-like protein N-terminal domain protein
HDBIHKAD_01196 3.4e-71
HDBIHKAD_01197 0.0 pacL 3.6.3.8 P P-type ATPase
HDBIHKAD_01198 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HDBIHKAD_01199 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDBIHKAD_01200 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HDBIHKAD_01201 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HDBIHKAD_01202 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HDBIHKAD_01203 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HDBIHKAD_01204 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HDBIHKAD_01205 4.7e-194 ybiR P Citrate transporter
HDBIHKAD_01206 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HDBIHKAD_01207 2.5e-53 S Cupin domain
HDBIHKAD_01208 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
HDBIHKAD_01212 1.3e-150 yjjH S Calcineurin-like phosphoesterase
HDBIHKAD_01213 3e-252 dtpT U amino acid peptide transporter
HDBIHKAD_01214 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_01215 1.4e-154 yihY S Belongs to the UPF0761 family
HDBIHKAD_01216 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HDBIHKAD_01217 1.2e-219 pbpX1 V Beta-lactamase
HDBIHKAD_01218 1.9e-253 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HDBIHKAD_01219 5e-107
HDBIHKAD_01220 1.3e-73
HDBIHKAD_01222 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_01223 1.4e-242 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_01224 2.3e-75 T Universal stress protein family
HDBIHKAD_01226 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HDBIHKAD_01227 2.4e-189 mocA S Oxidoreductase
HDBIHKAD_01228 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HDBIHKAD_01229 1.1e-62 S Domain of unknown function (DUF4828)
HDBIHKAD_01230 2e-143 lys M Glycosyl hydrolases family 25
HDBIHKAD_01231 2.3e-151 gntR K rpiR family
HDBIHKAD_01232 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_01233 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_01234 0.0 yfgQ P E1-E2 ATPase
HDBIHKAD_01235 6e-100 yobS K Bacterial regulatory proteins, tetR family
HDBIHKAD_01236 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HDBIHKAD_01237 1e-190 yegS 2.7.1.107 G Lipid kinase
HDBIHKAD_01238 3.8e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDBIHKAD_01239 2.1e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HDBIHKAD_01240 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HDBIHKAD_01241 2.6e-198 camS S sex pheromone
HDBIHKAD_01242 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HDBIHKAD_01243 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HDBIHKAD_01244 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HDBIHKAD_01245 1e-93 S UPF0316 protein
HDBIHKAD_01246 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HDBIHKAD_01247 9e-113 acmA 3.2.1.17 NU mannosyl-glycoprotein
HDBIHKAD_01248 1.1e-15 S Oxidoreductase family, NAD-binding Rossmann fold
HDBIHKAD_01249 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HDBIHKAD_01250 4.5e-132 mntB 3.6.3.35 P ABC transporter
HDBIHKAD_01251 8.2e-141 mtsB U ABC 3 transport family
HDBIHKAD_01252 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HDBIHKAD_01253 3.1e-50
HDBIHKAD_01254 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HDBIHKAD_01255 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
HDBIHKAD_01256 2.9e-179 citR K sugar-binding domain protein
HDBIHKAD_01257 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HDBIHKAD_01258 5.7e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HDBIHKAD_01259 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HDBIHKAD_01260 3.7e-160 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HDBIHKAD_01261 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HDBIHKAD_01262 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HDBIHKAD_01263 1.5e-261 frdC 1.3.5.4 C FAD binding domain
HDBIHKAD_01264 3.6e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HDBIHKAD_01265 4.9e-162 mleR K LysR family transcriptional regulator
HDBIHKAD_01266 1.2e-166 mleR K LysR family
HDBIHKAD_01267 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HDBIHKAD_01268 1.4e-165 mleP S Sodium Bile acid symporter family
HDBIHKAD_01269 5.8e-253 yfnA E Amino Acid
HDBIHKAD_01270 3e-99 S ECF transporter, substrate-specific component
HDBIHKAD_01271 1.8e-23
HDBIHKAD_01272 9.1e-308 S Alpha beta
HDBIHKAD_01273 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HDBIHKAD_01274 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HDBIHKAD_01275 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HDBIHKAD_01276 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HDBIHKAD_01277 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HDBIHKAD_01278 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDBIHKAD_01279 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HDBIHKAD_01280 2.5e-250 malT G Major Facilitator
HDBIHKAD_01281 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HDBIHKAD_01282 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDBIHKAD_01283 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HDBIHKAD_01284 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HDBIHKAD_01285 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HDBIHKAD_01286 9e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HDBIHKAD_01287 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HDBIHKAD_01288 2.1e-72 ypmB S protein conserved in bacteria
HDBIHKAD_01289 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HDBIHKAD_01290 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HDBIHKAD_01291 1.1e-127 dnaD L Replication initiation and membrane attachment
HDBIHKAD_01292 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HDBIHKAD_01293 2e-99 metI P ABC transporter permease
HDBIHKAD_01294 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HDBIHKAD_01295 4.4e-83 uspA T Universal stress protein family
HDBIHKAD_01296 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
HDBIHKAD_01297 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
HDBIHKAD_01298 1.8e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HDBIHKAD_01299 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HDBIHKAD_01300 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HDBIHKAD_01301 8.3e-110 ypsA S Belongs to the UPF0398 family
HDBIHKAD_01302 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HDBIHKAD_01304 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HDBIHKAD_01305 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_01306 6.1e-244 P Major Facilitator Superfamily
HDBIHKAD_01307 9.9e-111 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HDBIHKAD_01308 1.7e-09 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HDBIHKAD_01309 1.7e-72 S SnoaL-like domain
HDBIHKAD_01310 2.8e-241 M Glycosyltransferase, group 2 family protein
HDBIHKAD_01311 5.1e-209 mccF V LD-carboxypeptidase
HDBIHKAD_01312 1.4e-78 K Acetyltransferase (GNAT) domain
HDBIHKAD_01313 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
HDBIHKAD_01314 9.9e-180 proV E ABC transporter, ATP-binding protein
HDBIHKAD_01315 4e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDBIHKAD_01316 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HDBIHKAD_01317 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDBIHKAD_01318 4.5e-174 rihC 3.2.2.1 F Nucleoside
HDBIHKAD_01319 1.9e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDBIHKAD_01320 9.3e-80
HDBIHKAD_01321 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HDBIHKAD_01322 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
HDBIHKAD_01323 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
HDBIHKAD_01324 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HDBIHKAD_01325 4.2e-310 mco Q Multicopper oxidase
HDBIHKAD_01326 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HDBIHKAD_01327 1.9e-20 zmp1 O Zinc-dependent metalloprotease
HDBIHKAD_01328 3.7e-44
HDBIHKAD_01329 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HDBIHKAD_01330 4.7e-241 amtB P ammonium transporter
HDBIHKAD_01331 6e-258 P Major Facilitator Superfamily
HDBIHKAD_01332 2.8e-91 K Transcriptional regulator PadR-like family
HDBIHKAD_01333 8.4e-44
HDBIHKAD_01334 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HDBIHKAD_01335 6e-154 tagG U Transport permease protein
HDBIHKAD_01336 3.8e-218
HDBIHKAD_01337 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
HDBIHKAD_01338 1.8e-61 S CHY zinc finger
HDBIHKAD_01339 2.5e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HDBIHKAD_01340 5.7e-95 bioY S BioY family
HDBIHKAD_01341 3e-40
HDBIHKAD_01342 6.5e-281 pipD E Dipeptidase
HDBIHKAD_01343 1.1e-29
HDBIHKAD_01344 8.7e-122 qmcA O prohibitin homologues
HDBIHKAD_01345 1.5e-239 xylP1 G MFS/sugar transport protein
HDBIHKAD_01347 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HDBIHKAD_01348 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HDBIHKAD_01349 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
HDBIHKAD_01350 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDBIHKAD_01351 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDBIHKAD_01352 1.7e-19 S NUDIX domain
HDBIHKAD_01353 0.0 S membrane
HDBIHKAD_01354 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HDBIHKAD_01355 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HDBIHKAD_01356 3.1e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HDBIHKAD_01357 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HDBIHKAD_01358 9.3e-106 GBS0088 S Nucleotidyltransferase
HDBIHKAD_01359 1.6e-105
HDBIHKAD_01360 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HDBIHKAD_01361 3.3e-112 K Bacterial regulatory proteins, tetR family
HDBIHKAD_01362 2.1e-241 npr 1.11.1.1 C NADH oxidase
HDBIHKAD_01363 0.0
HDBIHKAD_01364 3.5e-61
HDBIHKAD_01365 9.3e-192 S Fn3-like domain
HDBIHKAD_01366 4e-103 S WxL domain surface cell wall-binding
HDBIHKAD_01367 3.5e-78 S WxL domain surface cell wall-binding
HDBIHKAD_01368 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HDBIHKAD_01369 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HDBIHKAD_01370 2e-42
HDBIHKAD_01371 9.9e-82 hit FG histidine triad
HDBIHKAD_01372 1.6e-134 ecsA V ABC transporter, ATP-binding protein
HDBIHKAD_01373 6.2e-224 ecsB U ABC transporter
HDBIHKAD_01374 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HDBIHKAD_01375 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HDBIHKAD_01376 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HDBIHKAD_01377 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDBIHKAD_01378 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HDBIHKAD_01379 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HDBIHKAD_01380 7.9e-21 S Virus attachment protein p12 family
HDBIHKAD_01381 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HDBIHKAD_01382 1.3e-34 feoA P FeoA domain
HDBIHKAD_01383 4.2e-144 sufC O FeS assembly ATPase SufC
HDBIHKAD_01384 2.6e-244 sufD O FeS assembly protein SufD
HDBIHKAD_01385 1.8e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HDBIHKAD_01386 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
HDBIHKAD_01387 1.4e-272 sufB O assembly protein SufB
HDBIHKAD_01388 5.5e-45 yitW S Iron-sulfur cluster assembly protein
HDBIHKAD_01389 3.1e-111 hipB K Helix-turn-helix
HDBIHKAD_01390 4.5e-121 ybhL S Belongs to the BI1 family
HDBIHKAD_01391 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HDBIHKAD_01392 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HDBIHKAD_01393 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HDBIHKAD_01394 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HDBIHKAD_01395 1.1e-248 dnaB L replication initiation and membrane attachment
HDBIHKAD_01396 1.2e-171 dnaI L Primosomal protein DnaI
HDBIHKAD_01397 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HDBIHKAD_01398 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HDBIHKAD_01399 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HDBIHKAD_01400 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HDBIHKAD_01401 1.1e-55
HDBIHKAD_01402 7.2e-239 yrvN L AAA C-terminal domain
HDBIHKAD_01403 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HDBIHKAD_01404 1e-62 hxlR K Transcriptional regulator, HxlR family
HDBIHKAD_01405 1e-84 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HDBIHKAD_01406 5e-41 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HDBIHKAD_01407 1e-248 pgaC GT2 M Glycosyl transferase
HDBIHKAD_01408 1.3e-79
HDBIHKAD_01409 1.4e-98 yqeG S HAD phosphatase, family IIIA
HDBIHKAD_01410 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
HDBIHKAD_01411 1.1e-50 yhbY J RNA-binding protein
HDBIHKAD_01412 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HDBIHKAD_01413 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HDBIHKAD_01414 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HDBIHKAD_01415 4.4e-140 yqeM Q Methyltransferase
HDBIHKAD_01416 7.5e-219 ylbM S Belongs to the UPF0348 family
HDBIHKAD_01417 1.6e-97 yceD S Uncharacterized ACR, COG1399
HDBIHKAD_01418 7e-88 S Peptidase propeptide and YPEB domain
HDBIHKAD_01419 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDBIHKAD_01420 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HDBIHKAD_01421 4.2e-245 rarA L recombination factor protein RarA
HDBIHKAD_01422 4.3e-121 K response regulator
HDBIHKAD_01423 8e-307 arlS 2.7.13.3 T Histidine kinase
HDBIHKAD_01424 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HDBIHKAD_01425 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HDBIHKAD_01426 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HDBIHKAD_01427 9.3e-93 S SdpI/YhfL protein family
HDBIHKAD_01428 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDBIHKAD_01429 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HDBIHKAD_01430 1.3e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDBIHKAD_01431 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDBIHKAD_01432 1.1e-62 yodB K Transcriptional regulator, HxlR family
HDBIHKAD_01433 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HDBIHKAD_01434 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HDBIHKAD_01435 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HDBIHKAD_01436 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HDBIHKAD_01437 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HDBIHKAD_01438 2.3e-96 liaI S membrane
HDBIHKAD_01439 4e-75 XK27_02470 K LytTr DNA-binding domain
HDBIHKAD_01440 1.5e-54 yneR S Belongs to the HesB IscA family
HDBIHKAD_01441 0.0 S membrane
HDBIHKAD_01442 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HDBIHKAD_01443 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDBIHKAD_01444 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HDBIHKAD_01445 3e-114 gluP 3.4.21.105 S Peptidase, S54 family
HDBIHKAD_01446 7.1e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HDBIHKAD_01447 1.7e-179 glk 2.7.1.2 G Glucokinase
HDBIHKAD_01448 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HDBIHKAD_01449 4.4e-68 yqhL P Rhodanese-like protein
HDBIHKAD_01450 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HDBIHKAD_01451 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
HDBIHKAD_01452 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HDBIHKAD_01453 4.6e-64 glnR K Transcriptional regulator
HDBIHKAD_01454 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
HDBIHKAD_01455 2e-161
HDBIHKAD_01456 4e-181
HDBIHKAD_01457 2.4e-98 dut S Protein conserved in bacteria
HDBIHKAD_01458 5.3e-56
HDBIHKAD_01459 1.7e-30
HDBIHKAD_01462 5.4e-19
HDBIHKAD_01463 1.8e-89 K Transcriptional regulator
HDBIHKAD_01464 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HDBIHKAD_01465 3.2e-53 ysxB J Cysteine protease Prp
HDBIHKAD_01466 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HDBIHKAD_01467 5.9e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HDBIHKAD_01468 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HDBIHKAD_01469 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HDBIHKAD_01470 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HDBIHKAD_01471 1.1e-150 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HDBIHKAD_01472 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDBIHKAD_01473 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HDBIHKAD_01474 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDBIHKAD_01475 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HDBIHKAD_01476 2.2e-76 argR K Regulates arginine biosynthesis genes
HDBIHKAD_01477 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HDBIHKAD_01478 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HDBIHKAD_01479 3.4e-104 opuCB E ABC transporter permease
HDBIHKAD_01480 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HDBIHKAD_01481 8.3e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HDBIHKAD_01482 4.5e-55
HDBIHKAD_01483 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HDBIHKAD_01484 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HDBIHKAD_01485 2.5e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HDBIHKAD_01486 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HDBIHKAD_01487 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HDBIHKAD_01488 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HDBIHKAD_01489 1.7e-134 stp 3.1.3.16 T phosphatase
HDBIHKAD_01490 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HDBIHKAD_01491 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDBIHKAD_01492 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HDBIHKAD_01493 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
HDBIHKAD_01494 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HDBIHKAD_01495 1.8e-57 asp S Asp23 family, cell envelope-related function
HDBIHKAD_01496 0.0 yloV S DAK2 domain fusion protein YloV
HDBIHKAD_01497 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HDBIHKAD_01498 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HDBIHKAD_01499 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDBIHKAD_01500 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HDBIHKAD_01501 0.0 smc D Required for chromosome condensation and partitioning
HDBIHKAD_01502 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HDBIHKAD_01503 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HDBIHKAD_01504 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HDBIHKAD_01505 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HDBIHKAD_01506 2.6e-39 ylqC S Belongs to the UPF0109 family
HDBIHKAD_01507 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HDBIHKAD_01508 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HDBIHKAD_01509 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HDBIHKAD_01510 6.8e-53
HDBIHKAD_01511 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HDBIHKAD_01512 5.3e-86
HDBIHKAD_01513 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HDBIHKAD_01514 9.9e-270 XK27_00765
HDBIHKAD_01515 2.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HDBIHKAD_01516 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HDBIHKAD_01517 2.7e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HDBIHKAD_01518 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HDBIHKAD_01519 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HDBIHKAD_01520 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HDBIHKAD_01521 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HDBIHKAD_01522 2e-97 entB 3.5.1.19 Q Isochorismatase family
HDBIHKAD_01523 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
HDBIHKAD_01524 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
HDBIHKAD_01525 5.8e-217 E glutamate:sodium symporter activity
HDBIHKAD_01526 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
HDBIHKAD_01527 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HDBIHKAD_01528 4.7e-58 S Protein of unknown function (DUF1648)
HDBIHKAD_01530 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDBIHKAD_01531 1.1e-178 yneE K Transcriptional regulator
HDBIHKAD_01532 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HDBIHKAD_01533 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HDBIHKAD_01534 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HDBIHKAD_01535 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HDBIHKAD_01536 2.1e-126 IQ reductase
HDBIHKAD_01537 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HDBIHKAD_01538 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HDBIHKAD_01539 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HDBIHKAD_01540 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HDBIHKAD_01541 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HDBIHKAD_01542 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HDBIHKAD_01543 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HDBIHKAD_01544 1.2e-97 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HDBIHKAD_01545 2.2e-123 S Protein of unknown function (DUF554)
HDBIHKAD_01546 1.6e-160 K LysR substrate binding domain
HDBIHKAD_01547 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
HDBIHKAD_01548 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HDBIHKAD_01549 7.5e-92 K transcriptional regulator
HDBIHKAD_01550 1.4e-301 norB EGP Major Facilitator
HDBIHKAD_01551 1.2e-139 f42a O Band 7 protein
HDBIHKAD_01552 8.5e-54
HDBIHKAD_01553 1.3e-28
HDBIHKAD_01554 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDBIHKAD_01555 8e-33 L hmm pf00665
HDBIHKAD_01556 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HDBIHKAD_01557 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HDBIHKAD_01558 7.9e-41
HDBIHKAD_01559 1.9e-67 tspO T TspO/MBR family
HDBIHKAD_01560 2.4e-75 uspA T Belongs to the universal stress protein A family
HDBIHKAD_01561 1e-65 S Protein of unknown function (DUF805)
HDBIHKAD_01562 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HDBIHKAD_01563 2.9e-35
HDBIHKAD_01564 3.1e-14
HDBIHKAD_01565 6.5e-41 S transglycosylase associated protein
HDBIHKAD_01566 4.8e-29 S CsbD-like
HDBIHKAD_01567 9.4e-40
HDBIHKAD_01568 8.6e-281 pipD E Dipeptidase
HDBIHKAD_01569 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HDBIHKAD_01570 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HDBIHKAD_01571 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
HDBIHKAD_01572 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HDBIHKAD_01573 1.9e-49
HDBIHKAD_01574 2.4e-43
HDBIHKAD_01575 5.1e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HDBIHKAD_01576 1.4e-265 yfnA E Amino Acid
HDBIHKAD_01577 1.2e-149 yitU 3.1.3.104 S hydrolase
HDBIHKAD_01578 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HDBIHKAD_01579 1.5e-89 S Domain of unknown function (DUF4767)
HDBIHKAD_01580 8.9e-213 S ATPases associated with a variety of cellular activities
HDBIHKAD_01581 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDBIHKAD_01582 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HDBIHKAD_01584 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDBIHKAD_01585 2.9e-162 FbpA K Domain of unknown function (DUF814)
HDBIHKAD_01586 1.3e-60 S Domain of unknown function (DU1801)
HDBIHKAD_01587 4.9e-34
HDBIHKAD_01588 1.1e-178 yghZ C Aldo keto reductase family protein
HDBIHKAD_01589 3e-113 pgm1 G phosphoglycerate mutase
HDBIHKAD_01590 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HDBIHKAD_01591 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDBIHKAD_01592 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
HDBIHKAD_01593 1.8e-309 oppA E ABC transporter, substratebinding protein
HDBIHKAD_01594 0.0 oppA E ABC transporter, substratebinding protein
HDBIHKAD_01595 2.1e-157 hipB K Helix-turn-helix
HDBIHKAD_01597 0.0 3.6.4.13 M domain protein
HDBIHKAD_01598 5e-27 mleR K LysR substrate binding domain
HDBIHKAD_01599 1.4e-127 mleR K LysR substrate binding domain
HDBIHKAD_01600 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDBIHKAD_01601 5.9e-218 nhaC C Na H antiporter NhaC
HDBIHKAD_01602 1.4e-164 3.5.1.10 C nadph quinone reductase
HDBIHKAD_01603 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDBIHKAD_01604 9.1e-173 scrR K Transcriptional regulator, LacI family
HDBIHKAD_01605 1.5e-304 scrB 3.2.1.26 GH32 G invertase
HDBIHKAD_01606 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HDBIHKAD_01607 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDBIHKAD_01608 1.8e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HDBIHKAD_01609 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
HDBIHKAD_01610 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
HDBIHKAD_01611 4.6e-129 yejC S Protein of unknown function (DUF1003)
HDBIHKAD_01612 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HDBIHKAD_01613 4.6e-12
HDBIHKAD_01614 2.7e-211 pmrB EGP Major facilitator Superfamily
HDBIHKAD_01615 9.6e-149 2.7.7.12 C Domain of unknown function (DUF4931)
HDBIHKAD_01616 5.4e-49
HDBIHKAD_01617 1.6e-09
HDBIHKAD_01618 2.9e-131 S Protein of unknown function (DUF975)
HDBIHKAD_01619 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HDBIHKAD_01620 2.1e-160 degV S EDD domain protein, DegV family
HDBIHKAD_01621 7.1e-66 K Transcriptional regulator
HDBIHKAD_01622 0.0 FbpA K Fibronectin-binding protein
HDBIHKAD_01623 9.3e-133 S ABC-2 family transporter protein
HDBIHKAD_01624 5.4e-164 V ABC transporter, ATP-binding protein
HDBIHKAD_01625 3e-92 3.6.1.55 F NUDIX domain
HDBIHKAD_01626 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HDBIHKAD_01627 1.2e-69 S LuxR family transcriptional regulator
HDBIHKAD_01628 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HDBIHKAD_01631 3.1e-71 frataxin S Domain of unknown function (DU1801)
HDBIHKAD_01632 6.4e-113 pgm5 G Phosphoglycerate mutase family
HDBIHKAD_01633 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDBIHKAD_01634 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
HDBIHKAD_01635 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDBIHKAD_01636 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDBIHKAD_01637 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HDBIHKAD_01638 2.3e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HDBIHKAD_01639 2.2e-61 esbA S Family of unknown function (DUF5322)
HDBIHKAD_01640 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HDBIHKAD_01641 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HDBIHKAD_01642 9.2e-104 S hydrolase activity, acting on ester bonds
HDBIHKAD_01643 4.2e-21 S hydrolase activity, acting on ester bonds
HDBIHKAD_01644 2.3e-193
HDBIHKAD_01645 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HDBIHKAD_01646 1.3e-123
HDBIHKAD_01647 1.3e-179 mccF 3.4.17.13 V LD-carboxypeptidase
HDBIHKAD_01648 2.6e-239 M hydrolase, family 25
HDBIHKAD_01649 1.1e-16 glf 5.4.99.9 M UDP-galactopyranose mutase
HDBIHKAD_01650 2.3e-145 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HDBIHKAD_01651 1.4e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HDBIHKAD_01652 9.7e-73 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HDBIHKAD_01655 1e-07 S by MetaGeneAnnotator
HDBIHKAD_01656 1.5e-24 3.4.22.70 M Sortase family
HDBIHKAD_01659 2.6e-125 clpB O Belongs to the ClpA ClpB family
HDBIHKAD_01662 9.6e-34 L Protein of unknown function (DUF3991)
HDBIHKAD_01665 1.3e-261 traI 5.99.1.2 L C-terminal repeat of topoisomerase
HDBIHKAD_01666 1e-13 XK27_07075 S CAAX protease self-immunity
HDBIHKAD_01667 2e-42 ruvB 3.6.4.12 L four-way junction helicase activity
HDBIHKAD_01676 1.9e-34 S Protein of unknown function (DUF3102)
HDBIHKAD_01677 1.2e-13
HDBIHKAD_01678 2.8e-96 M CHAP domain
HDBIHKAD_01680 2.2e-125 U type IV secretory pathway VirB4
HDBIHKAD_01681 9.5e-17
HDBIHKAD_01683 6e-13 I mechanosensitive ion channel activity
HDBIHKAD_01684 8.3e-254 gor 1.8.1.7 C Glutathione reductase
HDBIHKAD_01685 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HDBIHKAD_01686 4.1e-18
HDBIHKAD_01687 2.8e-243
HDBIHKAD_01688 8e-196 M MucBP domain
HDBIHKAD_01689 7.1e-161 lysR5 K LysR substrate binding domain
HDBIHKAD_01690 5.5e-126 yxaA S membrane transporter protein
HDBIHKAD_01691 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HDBIHKAD_01692 1.3e-309 oppA E ABC transporter, substratebinding protein
HDBIHKAD_01693 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDBIHKAD_01694 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HDBIHKAD_01695 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HDBIHKAD_01696 1.8e-181 oppF P Belongs to the ABC transporter superfamily
HDBIHKAD_01697 1e-63 K Winged helix DNA-binding domain
HDBIHKAD_01698 2.2e-73 L Integrase
HDBIHKAD_01699 0.0 clpE O Belongs to the ClpA ClpB family
HDBIHKAD_01700 6.5e-30
HDBIHKAD_01701 2.7e-39 ptsH G phosphocarrier protein HPR
HDBIHKAD_01702 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HDBIHKAD_01703 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HDBIHKAD_01704 3.4e-199 cpoA GT4 M Glycosyltransferase, group 1 family protein
HDBIHKAD_01705 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDBIHKAD_01706 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HDBIHKAD_01707 1.1e-225 patA 2.6.1.1 E Aminotransferase
HDBIHKAD_01708 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HDBIHKAD_01709 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDBIHKAD_01710 1.9e-125 S CAAX protease self-immunity
HDBIHKAD_01711 2.4e-22 plnF
HDBIHKAD_01712 5.5e-13
HDBIHKAD_01713 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HDBIHKAD_01714 2.2e-241 mesE M Transport protein ComB
HDBIHKAD_01715 1.4e-108 S CAAX protease self-immunity
HDBIHKAD_01716 7.4e-118 ypbD S CAAX protease self-immunity
HDBIHKAD_01717 1.2e-110 V CAAX protease self-immunity
HDBIHKAD_01718 1.1e-113 S CAAX protease self-immunity
HDBIHKAD_01719 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
HDBIHKAD_01720 0.0 helD 3.6.4.12 L DNA helicase
HDBIHKAD_01721 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HDBIHKAD_01722 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDBIHKAD_01723 9e-130 K UbiC transcription regulator-associated domain protein
HDBIHKAD_01724 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_01725 3.9e-24
HDBIHKAD_01726 1.9e-74 S Domain of unknown function (DUF3284)
HDBIHKAD_01727 4.8e-34
HDBIHKAD_01728 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDBIHKAD_01729 4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDBIHKAD_01730 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDBIHKAD_01731 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HDBIHKAD_01732 2.7e-177
HDBIHKAD_01733 3.9e-133 cobB K SIR2 family
HDBIHKAD_01734 2e-160 yunF F Protein of unknown function DUF72
HDBIHKAD_01735 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HDBIHKAD_01736 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HDBIHKAD_01737 2e-214 bcr1 EGP Major facilitator Superfamily
HDBIHKAD_01738 1.3e-83 mutR K sequence-specific DNA binding
HDBIHKAD_01740 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HDBIHKAD_01741 1.7e-99
HDBIHKAD_01742 0.0 1.3.5.4 C FAD binding domain
HDBIHKAD_01743 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
HDBIHKAD_01744 8.5e-176 K LysR substrate binding domain
HDBIHKAD_01745 3.1e-181 3.4.21.102 M Peptidase family S41
HDBIHKAD_01746 2.1e-213
HDBIHKAD_01747 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDBIHKAD_01748 0.0 L AAA domain
HDBIHKAD_01749 1.7e-232 yhaO L Ser Thr phosphatase family protein
HDBIHKAD_01750 1e-54 yheA S Belongs to the UPF0342 family
HDBIHKAD_01751 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HDBIHKAD_01752 2.9e-12
HDBIHKAD_01753 4.4e-77 argR K Regulates arginine biosynthesis genes
HDBIHKAD_01754 7.1e-214 arcT 2.6.1.1 E Aminotransferase
HDBIHKAD_01755 1.4e-102 argO S LysE type translocator
HDBIHKAD_01756 2.3e-162 ydfD K Alanine-glyoxylate amino-transferase
HDBIHKAD_01757 5.8e-79 ydfD K Alanine-glyoxylate amino-transferase
HDBIHKAD_01758 2e-33 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HDBIHKAD_01759 4.9e-41 M ErfK YbiS YcfS YnhG
HDBIHKAD_01760 1.3e-53 M ErfK YbiS YcfS YnhG
HDBIHKAD_01761 9.5e-209 EGP Major facilitator Superfamily
HDBIHKAD_01762 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDBIHKAD_01763 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_01764 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_01765 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HDBIHKAD_01766 2.4e-62 S Domain of unknown function (DUF3284)
HDBIHKAD_01767 0.0 K PRD domain
HDBIHKAD_01768 1.1e-105
HDBIHKAD_01769 7.4e-80
HDBIHKAD_01770 2.2e-263 traK U TraM recognition site of TraD and TraG
HDBIHKAD_01771 1.8e-60
HDBIHKAD_01772 5.9e-152
HDBIHKAD_01773 4.6e-62
HDBIHKAD_01774 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDBIHKAD_01775 5e-08
HDBIHKAD_01776 2.8e-187 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HDBIHKAD_01778 0.0 KL Helicase conserved C-terminal domain
HDBIHKAD_01779 3.4e-208 S Domain of unknown function (DUF1998)
HDBIHKAD_01780 6.8e-53
HDBIHKAD_01781 2e-244 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDBIHKAD_01782 3.1e-146 L COG3547 Transposase and inactivated derivatives
HDBIHKAD_01783 5.8e-203 3.3.1.1 H adenosylhomocysteinase activity
HDBIHKAD_01784 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDBIHKAD_01785 2.8e-220 EGP Major facilitator Superfamily
HDBIHKAD_01786 2.7e-14 2.7.11.1 K FRG
HDBIHKAD_01787 8.3e-08 S FRG
HDBIHKAD_01788 1.9e-46 3.2.1.4 GH5,GH9 M domain protein
HDBIHKAD_01789 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDBIHKAD_01790 4.3e-144 yxeH S hydrolase
HDBIHKAD_01791 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDBIHKAD_01792 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HDBIHKAD_01793 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HDBIHKAD_01794 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
HDBIHKAD_01795 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDBIHKAD_01796 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDBIHKAD_01797 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
HDBIHKAD_01798 2.3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HDBIHKAD_01799 1.1e-231 gatC G PTS system sugar-specific permease component
HDBIHKAD_01800 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_01801 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HDBIHKAD_01802 7e-112 K DeoR C terminal sensor domain
HDBIHKAD_01803 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDBIHKAD_01804 7.4e-136 K Helix-turn-helix domain, rpiR family
HDBIHKAD_01805 3.7e-72 yueI S Protein of unknown function (DUF1694)
HDBIHKAD_01806 2.9e-164 I alpha/beta hydrolase fold
HDBIHKAD_01807 1.3e-159 I alpha/beta hydrolase fold
HDBIHKAD_01808 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HDBIHKAD_01809 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDBIHKAD_01810 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HDBIHKAD_01811 5.4e-153 nanK GK ROK family
HDBIHKAD_01812 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HDBIHKAD_01824 5.5e-08
HDBIHKAD_01834 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HDBIHKAD_01835 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
HDBIHKAD_01836 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HDBIHKAD_01837 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HDBIHKAD_01838 2e-13 coiA 3.6.4.12 S Competence protein
HDBIHKAD_01839 2e-180 coiA 3.6.4.12 S Competence protein
HDBIHKAD_01840 0.0 pepF E oligoendopeptidase F
HDBIHKAD_01841 8.9e-113 yjbH Q Thioredoxin
HDBIHKAD_01842 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HDBIHKAD_01843 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HDBIHKAD_01844 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HDBIHKAD_01845 1.1e-115 cutC P Participates in the control of copper homeostasis
HDBIHKAD_01846 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HDBIHKAD_01847 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDBIHKAD_01848 4.3e-206 XK27_05220 S AI-2E family transporter
HDBIHKAD_01849 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HDBIHKAD_01850 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
HDBIHKAD_01852 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
HDBIHKAD_01853 2.4e-113 ywnB S NAD(P)H-binding
HDBIHKAD_01854 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HDBIHKAD_01855 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HDBIHKAD_01856 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDBIHKAD_01857 1.9e-63
HDBIHKAD_01858 5.3e-153
HDBIHKAD_01859 7.7e-56
HDBIHKAD_01860 2.7e-256 traK U TraM recognition site of TraD and TraG
HDBIHKAD_01861 6.7e-73
HDBIHKAD_01862 4.3e-59 CO COG0526, thiol-disulfide isomerase and thioredoxins
HDBIHKAD_01863 6.9e-86
HDBIHKAD_01864 2.6e-203 M CHAP domain
HDBIHKAD_01865 4.9e-220 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HDBIHKAD_01866 0.0 traE U type IV secretory pathway VirB4
HDBIHKAD_01867 6.2e-117
HDBIHKAD_01868 8.3e-31
HDBIHKAD_01869 8.7e-51 S Cag pathogenicity island, type IV secretory system
HDBIHKAD_01870 2e-93
HDBIHKAD_01871 3.5e-41
HDBIHKAD_01872 0.0 L MobA MobL family protein
HDBIHKAD_01873 1.5e-24
HDBIHKAD_01874 2.3e-36
HDBIHKAD_01875 4.2e-38 S protein conserved in bacteria
HDBIHKAD_01876 2.8e-15
HDBIHKAD_01877 8e-255 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_01878 0.0 1.3.5.4 C FMN_bind
HDBIHKAD_01879 1.6e-152 K LysR family
HDBIHKAD_01880 6e-15 K Bacterial regulatory proteins, tetR family
HDBIHKAD_01882 3.9e-162 K Transcriptional regulator
HDBIHKAD_01883 1.1e-161 akr5f 1.1.1.346 S reductase
HDBIHKAD_01884 1.4e-164 S Oxidoreductase, aldo keto reductase family protein
HDBIHKAD_01885 3e-78 K Winged helix DNA-binding domain
HDBIHKAD_01886 6.4e-268 ycaM E amino acid
HDBIHKAD_01887 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HDBIHKAD_01888 2.7e-32
HDBIHKAD_01889 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HDBIHKAD_01890 0.0 M Bacterial Ig-like domain (group 3)
HDBIHKAD_01891 4.2e-77 fld C Flavodoxin
HDBIHKAD_01892 1.3e-216
HDBIHKAD_01893 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HDBIHKAD_01894 9.4e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HDBIHKAD_01895 1.4e-151 EG EamA-like transporter family
HDBIHKAD_01896 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HDBIHKAD_01897 9.8e-152 S hydrolase
HDBIHKAD_01898 1.8e-81
HDBIHKAD_01899 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HDBIHKAD_01900 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HDBIHKAD_01901 9.9e-129 gntR K UTRA
HDBIHKAD_01902 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_01903 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HDBIHKAD_01904 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDBIHKAD_01905 2.6e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDBIHKAD_01906 1.7e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HDBIHKAD_01907 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HDBIHKAD_01908 1.1e-151 V ABC transporter
HDBIHKAD_01909 2.8e-117 K Transcriptional regulator
HDBIHKAD_01910 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HDBIHKAD_01911 3.6e-88 niaR S 3H domain
HDBIHKAD_01912 2.1e-232 S Sterol carrier protein domain
HDBIHKAD_01913 1.4e-211 S Bacterial protein of unknown function (DUF871)
HDBIHKAD_01914 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
HDBIHKAD_01915 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
HDBIHKAD_01916 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HDBIHKAD_01917 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
HDBIHKAD_01918 9.3e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDBIHKAD_01919 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
HDBIHKAD_01920 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_01921 1.1e-281 thrC 4.2.3.1 E Threonine synthase
HDBIHKAD_01922 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HDBIHKAD_01924 1.5e-52
HDBIHKAD_01925 5.4e-118
HDBIHKAD_01926 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HDBIHKAD_01927 6.6e-234 malY 4.4.1.8 E Aminotransferase, class I
HDBIHKAD_01929 3.2e-50
HDBIHKAD_01930 1.1e-88
HDBIHKAD_01931 5.5e-71 gtcA S Teichoic acid glycosylation protein
HDBIHKAD_01932 4e-34
HDBIHKAD_01933 1.9e-80 uspA T universal stress protein
HDBIHKAD_01934 5.1e-137
HDBIHKAD_01935 6.9e-164 V ABC transporter, ATP-binding protein
HDBIHKAD_01936 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HDBIHKAD_01937 2.2e-39
HDBIHKAD_01938 0.0 V FtsX-like permease family
HDBIHKAD_01939 1.7e-139 cysA V ABC transporter, ATP-binding protein
HDBIHKAD_01940 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HDBIHKAD_01941 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_01942 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HDBIHKAD_01943 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HDBIHKAD_01944 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HDBIHKAD_01945 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HDBIHKAD_01946 4.3e-223 XK27_09615 1.3.5.4 S reductase
HDBIHKAD_01947 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HDBIHKAD_01948 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HDBIHKAD_01949 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HDBIHKAD_01950 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDBIHKAD_01951 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDBIHKAD_01952 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HDBIHKAD_01953 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HDBIHKAD_01954 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HDBIHKAD_01955 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HDBIHKAD_01956 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HDBIHKAD_01957 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
HDBIHKAD_01958 1e-122 2.1.1.14 E Methionine synthase
HDBIHKAD_01959 9.2e-253 pgaC GT2 M Glycosyl transferase
HDBIHKAD_01960 2.6e-94
HDBIHKAD_01961 6.5e-156 T EAL domain
HDBIHKAD_01962 5.6e-161 GM NmrA-like family
HDBIHKAD_01963 2.4e-221 pbuG S Permease family
HDBIHKAD_01964 2.7e-236 pbuX F xanthine permease
HDBIHKAD_01965 1e-298 pucR QT Purine catabolism regulatory protein-like family
HDBIHKAD_01966 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HDBIHKAD_01967 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HDBIHKAD_01968 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HDBIHKAD_01969 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HDBIHKAD_01970 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HDBIHKAD_01971 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HDBIHKAD_01972 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HDBIHKAD_01973 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HDBIHKAD_01974 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HDBIHKAD_01975 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HDBIHKAD_01976 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HDBIHKAD_01977 8.2e-96 wecD K Acetyltransferase (GNAT) family
HDBIHKAD_01978 5.6e-115 ylbE GM NAD(P)H-binding
HDBIHKAD_01979 1.9e-161 mleR K LysR family
HDBIHKAD_01980 1.7e-126 S membrane transporter protein
HDBIHKAD_01981 3e-18
HDBIHKAD_01982 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HDBIHKAD_01983 8.5e-218 patA 2.6.1.1 E Aminotransferase
HDBIHKAD_01984 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
HDBIHKAD_01985 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HDBIHKAD_01986 8.5e-57 S SdpI/YhfL protein family
HDBIHKAD_01987 1.9e-127 C Zinc-binding dehydrogenase
HDBIHKAD_01988 3e-30 C Zinc-binding dehydrogenase
HDBIHKAD_01989 5e-63 K helix_turn_helix, mercury resistance
HDBIHKAD_01990 2.8e-213 yttB EGP Major facilitator Superfamily
HDBIHKAD_01991 2.9e-269 yjcE P Sodium proton antiporter
HDBIHKAD_01992 4.9e-87 nrdI F Belongs to the NrdI family
HDBIHKAD_01993 1.2e-239 yhdP S Transporter associated domain
HDBIHKAD_01994 4.4e-58
HDBIHKAD_01995 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HDBIHKAD_01996 7.7e-61
HDBIHKAD_01997 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HDBIHKAD_01998 5.5e-138 rrp8 K LytTr DNA-binding domain
HDBIHKAD_01999 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDBIHKAD_02000 1.5e-138
HDBIHKAD_02001 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HDBIHKAD_02002 2.4e-130 gntR2 K Transcriptional regulator
HDBIHKAD_02003 2.3e-164 S Putative esterase
HDBIHKAD_02004 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HDBIHKAD_02005 2.3e-223 lsgC M Glycosyl transferases group 1
HDBIHKAD_02006 3.3e-21 S Protein of unknown function (DUF2929)
HDBIHKAD_02007 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HDBIHKAD_02008 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HDBIHKAD_02009 1.6e-79 uspA T universal stress protein
HDBIHKAD_02010 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HDBIHKAD_02011 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HDBIHKAD_02012 4e-60
HDBIHKAD_02013 3.7e-73
HDBIHKAD_02014 5e-82 yybC S Protein of unknown function (DUF2798)
HDBIHKAD_02015 1.7e-45
HDBIHKAD_02016 5.2e-47
HDBIHKAD_02017 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HDBIHKAD_02018 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HDBIHKAD_02019 8.4e-145 yjfP S Dienelactone hydrolase family
HDBIHKAD_02020 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02021 6.5e-47
HDBIHKAD_02022 1.3e-57
HDBIHKAD_02023 2.3e-164
HDBIHKAD_02024 1.3e-72 K Transcriptional regulator
HDBIHKAD_02025 0.0 pepF2 E Oligopeptidase F
HDBIHKAD_02026 3.8e-173 D Alpha beta
HDBIHKAD_02027 1.8e-44 S Enterocin A Immunity
HDBIHKAD_02028 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
HDBIHKAD_02029 8.7e-125 skfE V ABC transporter
HDBIHKAD_02030 2.7e-132
HDBIHKAD_02031 3.7e-107 pncA Q Isochorismatase family
HDBIHKAD_02032 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HDBIHKAD_02033 0.0 yjcE P Sodium proton antiporter
HDBIHKAD_02034 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HDBIHKAD_02035 5.1e-176 S Oxidoreductase family, NAD-binding Rossmann fold
HDBIHKAD_02036 1.1e-116 K Helix-turn-helix domain, rpiR family
HDBIHKAD_02037 2.3e-157 ccpB 5.1.1.1 K lacI family
HDBIHKAD_02038 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_02039 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDBIHKAD_02040 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HDBIHKAD_02041 1.2e-97 drgA C Nitroreductase family
HDBIHKAD_02042 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HDBIHKAD_02043 5.9e-182 3.6.4.13 S domain, Protein
HDBIHKAD_02044 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_02045 8.9e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HDBIHKAD_02046 7e-40
HDBIHKAD_02048 1.3e-249 EGP Major facilitator Superfamily
HDBIHKAD_02049 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HDBIHKAD_02050 4.7e-83 cvpA S Colicin V production protein
HDBIHKAD_02051 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HDBIHKAD_02052 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HDBIHKAD_02053 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HDBIHKAD_02054 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HDBIHKAD_02055 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HDBIHKAD_02056 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
HDBIHKAD_02057 6.5e-96 tag 3.2.2.20 L glycosylase
HDBIHKAD_02058 2.6e-19
HDBIHKAD_02059 2.7e-160 czcD P cation diffusion facilitator family transporter
HDBIHKAD_02060 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_02061 3e-116 hly S protein, hemolysin III
HDBIHKAD_02062 1.1e-44 qacH U Small Multidrug Resistance protein
HDBIHKAD_02063 5.8e-59 qacC P Small Multidrug Resistance protein
HDBIHKAD_02064 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HDBIHKAD_02065 5.3e-179 K AI-2E family transporter
HDBIHKAD_02066 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HDBIHKAD_02067 0.0 kup P Transport of potassium into the cell
HDBIHKAD_02069 8.6e-257 yhdG E C-terminus of AA_permease
HDBIHKAD_02070 2.1e-88 brnQ U Component of the transport system for branched-chain amino acids
HDBIHKAD_02071 1.3e-148 S hydrolase
HDBIHKAD_02072 1.2e-165 K Transcriptional regulator
HDBIHKAD_02073 3.4e-146 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_02074 1.1e-196 uhpT EGP Major facilitator Superfamily
HDBIHKAD_02075 3.6e-119 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HDBIHKAD_02076 6.1e-19 S Barstar (barnase inhibitor)
HDBIHKAD_02077 1.4e-61
HDBIHKAD_02078 4.2e-16
HDBIHKAD_02079 1.1e-07
HDBIHKAD_02080 1.1e-21
HDBIHKAD_02081 4.8e-69
HDBIHKAD_02082 2.8e-47 U nuclease activity
HDBIHKAD_02083 4.8e-20
HDBIHKAD_02084 3.3e-29
HDBIHKAD_02085 1.3e-99 ankB S ankyrin repeats
HDBIHKAD_02086 8.1e-08 S Immunity protein 22
HDBIHKAD_02087 4.8e-176
HDBIHKAD_02088 4.4e-25 S Immunity protein 74
HDBIHKAD_02089 5.1e-52 U domain, Protein
HDBIHKAD_02090 5.1e-238 M domain protein
HDBIHKAD_02091 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HDBIHKAD_02092 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HDBIHKAD_02093 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDBIHKAD_02094 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
HDBIHKAD_02095 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HDBIHKAD_02096 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HDBIHKAD_02097 2.7e-160 rbsU U ribose uptake protein RbsU
HDBIHKAD_02098 3.8e-145 IQ NAD dependent epimerase/dehydratase family
HDBIHKAD_02099 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HDBIHKAD_02100 1.1e-86 gutM K Glucitol operon activator protein (GutM)
HDBIHKAD_02101 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HDBIHKAD_02102 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HDBIHKAD_02103 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HDBIHKAD_02104 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02105 8.7e-72 K Transcriptional regulator
HDBIHKAD_02106 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02107 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDBIHKAD_02108 8.3e-52 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HDBIHKAD_02110 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HDBIHKAD_02111 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HDBIHKAD_02112 1.8e-12
HDBIHKAD_02113 8.7e-160 2.7.13.3 T GHKL domain
HDBIHKAD_02114 7.4e-135 K LytTr DNA-binding domain
HDBIHKAD_02115 4.9e-78 yneH 1.20.4.1 K ArsC family
HDBIHKAD_02116 4.5e-261 cps4J S Polysaccharide biosynthesis protein
HDBIHKAD_02117 5.5e-250 cpdA S Calcineurin-like phosphoesterase
HDBIHKAD_02118 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HDBIHKAD_02119 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HDBIHKAD_02120 1.5e-135 fruR K DeoR C terminal sensor domain
HDBIHKAD_02121 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HDBIHKAD_02122 3.2e-46
HDBIHKAD_02123 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HDBIHKAD_02124 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HDBIHKAD_02125 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HDBIHKAD_02126 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HDBIHKAD_02127 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HDBIHKAD_02128 1.5e-98 K Helix-turn-helix domain
HDBIHKAD_02129 6.1e-211 EGP Major facilitator Superfamily
HDBIHKAD_02130 8.5e-57 ybjQ S Belongs to the UPF0145 family
HDBIHKAD_02131 1.1e-138 Q Methyltransferase
HDBIHKAD_02132 1.6e-31
HDBIHKAD_02134 2.2e-229 rodA D Cell cycle protein
HDBIHKAD_02135 6.3e-213 opuAB P Binding-protein-dependent transport system inner membrane component
HDBIHKAD_02136 2.9e-64 G Transmembrane secretion effector
HDBIHKAD_02137 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HDBIHKAD_02138 1.5e-141
HDBIHKAD_02140 1.9e-71 spxA 1.20.4.1 P ArsC family
HDBIHKAD_02141 1.5e-33
HDBIHKAD_02142 2.5e-89 V VanZ like family
HDBIHKAD_02143 3.6e-242 EGP Major facilitator Superfamily
HDBIHKAD_02144 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDBIHKAD_02145 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HDBIHKAD_02146 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HDBIHKAD_02147 2.5e-152 licD M LicD family
HDBIHKAD_02148 1.2e-82 K Transcriptional regulator
HDBIHKAD_02149 1.5e-19
HDBIHKAD_02150 1.2e-225 pbuG S permease
HDBIHKAD_02151 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02152 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HDBIHKAD_02153 4.1e-119 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02154 6.7e-104 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HDBIHKAD_02155 0.0 rafA 3.2.1.22 G alpha-galactosidase
HDBIHKAD_02156 0.0 lacS G Transporter
HDBIHKAD_02157 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDBIHKAD_02158 1.1e-173 galR K Transcriptional regulator
HDBIHKAD_02159 8.2e-193 C Aldo keto reductase family protein
HDBIHKAD_02160 5.2e-65 S pyridoxamine 5-phosphate
HDBIHKAD_02161 0.0 1.3.5.4 C FAD binding domain
HDBIHKAD_02162 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDBIHKAD_02163 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HDBIHKAD_02164 2.7e-214 ydiM G Transporter
HDBIHKAD_02165 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDBIHKAD_02166 3.4e-163 K Transcriptional regulator, LysR family
HDBIHKAD_02167 1.8e-210 ydiN G Major Facilitator Superfamily
HDBIHKAD_02168 1e-63
HDBIHKAD_02169 3.4e-154 estA S Putative esterase
HDBIHKAD_02170 1.2e-134 K UTRA domain
HDBIHKAD_02171 3.6e-53 lytE M LysM domain protein
HDBIHKAD_02172 7.4e-67 gcvH E Glycine cleavage H-protein
HDBIHKAD_02173 2.8e-176 sepS16B
HDBIHKAD_02174 1.8e-130
HDBIHKAD_02175 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HDBIHKAD_02176 6.8e-57
HDBIHKAD_02177 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HDBIHKAD_02178 4.9e-24 elaA S GNAT family
HDBIHKAD_02179 1.7e-75 K Transcriptional regulator
HDBIHKAD_02180 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HDBIHKAD_02181 4.3e-40
HDBIHKAD_02182 4.4e-205 potD P ABC transporter
HDBIHKAD_02183 2.9e-140 potC P ABC transporter permease
HDBIHKAD_02184 4.5e-149 potB P ABC transporter permease
HDBIHKAD_02185 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HDBIHKAD_02186 1.3e-96 puuR K Cupin domain
HDBIHKAD_02187 1.1e-83 6.3.3.2 S ASCH
HDBIHKAD_02188 1e-84 K GNAT family
HDBIHKAD_02189 8e-91 K acetyltransferase
HDBIHKAD_02190 8.1e-22
HDBIHKAD_02191 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HDBIHKAD_02192 2e-163 ytrB V ABC transporter
HDBIHKAD_02193 1e-29
HDBIHKAD_02194 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HDBIHKAD_02195 1.3e-66 S Iron-sulphur cluster biosynthesis
HDBIHKAD_02196 1.8e-113 S GyrI-like small molecule binding domain
HDBIHKAD_02197 2.4e-187 S Cell surface protein
HDBIHKAD_02198 2.2e-100 S WxL domain surface cell wall-binding
HDBIHKAD_02199 1.1e-62
HDBIHKAD_02200 2.6e-209 NU Mycoplasma protein of unknown function, DUF285
HDBIHKAD_02201 5.9e-117
HDBIHKAD_02202 1e-116 S Haloacid dehalogenase-like hydrolase
HDBIHKAD_02203 2e-61 K Transcriptional regulator, HxlR family
HDBIHKAD_02204 5.1e-210 ytbD EGP Major facilitator Superfamily
HDBIHKAD_02205 1.4e-94 M ErfK YbiS YcfS YnhG
HDBIHKAD_02206 0.0 asnB 6.3.5.4 E Asparagine synthase
HDBIHKAD_02207 1.7e-134 K LytTr DNA-binding domain
HDBIHKAD_02208 1.3e-203 2.7.13.3 T GHKL domain
HDBIHKAD_02209 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
HDBIHKAD_02210 2.6e-291 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HDBIHKAD_02211 5e-117 yugP S Putative neutral zinc metallopeptidase
HDBIHKAD_02212 4.1e-25
HDBIHKAD_02213 7.1e-145 DegV S EDD domain protein, DegV family
HDBIHKAD_02214 7.3e-127 lrgB M LrgB-like family
HDBIHKAD_02215 5.1e-64 lrgA S LrgA family
HDBIHKAD_02216 3.8e-104 J Acetyltransferase (GNAT) domain
HDBIHKAD_02217 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HDBIHKAD_02218 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HDBIHKAD_02219 5.4e-36 S Phospholipase_D-nuclease N-terminal
HDBIHKAD_02220 7.1e-59 S Enterocin A Immunity
HDBIHKAD_02221 1.3e-87 perR P Belongs to the Fur family
HDBIHKAD_02222 8.4e-105
HDBIHKAD_02223 7.9e-238 S module of peptide synthetase
HDBIHKAD_02224 1.1e-77 S NADPH-dependent FMN reductase
HDBIHKAD_02225 1.4e-08
HDBIHKAD_02226 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
HDBIHKAD_02227 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HDBIHKAD_02228 9e-156 1.6.5.2 GM NmrA-like family
HDBIHKAD_02229 2e-77 merR K MerR family regulatory protein
HDBIHKAD_02230 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HDBIHKAD_02231 1.5e-272 hsdM 2.1.1.72 V type I restriction-modification system
HDBIHKAD_02232 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDBIHKAD_02233 0.0 pepN 3.4.11.2 E aminopeptidase
HDBIHKAD_02234 1.1e-101 G Glycogen debranching enzyme
HDBIHKAD_02235 5.3e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HDBIHKAD_02236 7.9e-156 yjdB S Domain of unknown function (DUF4767)
HDBIHKAD_02237 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
HDBIHKAD_02238 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HDBIHKAD_02239 8.7e-72 asp S Asp23 family, cell envelope-related function
HDBIHKAD_02240 7.2e-23
HDBIHKAD_02241 4.4e-84
HDBIHKAD_02242 7.1e-37 S Transglycosylase associated protein
HDBIHKAD_02243 0.0 XK27_09800 I Acyltransferase family
HDBIHKAD_02244 2.2e-37 S MORN repeat
HDBIHKAD_02245 4.6e-25 S Cysteine-rich secretory protein family
HDBIHKAD_02246 1.9e-113 EG EamA-like transporter family
HDBIHKAD_02247 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDBIHKAD_02248 5.2e-113 zmp2 O Zinc-dependent metalloprotease
HDBIHKAD_02249 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
HDBIHKAD_02250 9.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HDBIHKAD_02251 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HDBIHKAD_02252 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HDBIHKAD_02253 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HDBIHKAD_02254 3.7e-205 yacL S domain protein
HDBIHKAD_02255 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HDBIHKAD_02256 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDBIHKAD_02257 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HDBIHKAD_02258 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HDBIHKAD_02259 7.7e-97 yacP S YacP-like NYN domain
HDBIHKAD_02260 2.4e-101 sigH K Sigma-70 region 2
HDBIHKAD_02261 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HDBIHKAD_02262 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HDBIHKAD_02263 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HDBIHKAD_02264 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_02265 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HDBIHKAD_02266 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HDBIHKAD_02267 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HDBIHKAD_02268 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HDBIHKAD_02269 9.3e-178 F DNA/RNA non-specific endonuclease
HDBIHKAD_02270 1.2e-38 L nuclease
HDBIHKAD_02271 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HDBIHKAD_02272 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HDBIHKAD_02273 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDBIHKAD_02274 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDBIHKAD_02275 6.5e-37 nrdH O Glutaredoxin
HDBIHKAD_02276 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
HDBIHKAD_02277 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HDBIHKAD_02278 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HDBIHKAD_02279 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HDBIHKAD_02280 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HDBIHKAD_02281 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HDBIHKAD_02282 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HDBIHKAD_02283 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HDBIHKAD_02284 3.3e-186 holB 2.7.7.7 L DNA polymerase III
HDBIHKAD_02285 1e-57 yabA L Involved in initiation control of chromosome replication
HDBIHKAD_02286 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HDBIHKAD_02287 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HDBIHKAD_02288 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HDBIHKAD_02289 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HDBIHKAD_02290 2.5e-144 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HDBIHKAD_02291 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
HDBIHKAD_02292 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HDBIHKAD_02293 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HDBIHKAD_02294 5.1e-190 phnD P Phosphonate ABC transporter
HDBIHKAD_02295 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HDBIHKAD_02296 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HDBIHKAD_02297 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HDBIHKAD_02298 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HDBIHKAD_02299 3.3e-307 uup S ABC transporter, ATP-binding protein
HDBIHKAD_02300 1.8e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HDBIHKAD_02301 6.1e-109 ydiL S CAAX protease self-immunity
HDBIHKAD_02302 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HDBIHKAD_02303 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HDBIHKAD_02304 0.0 ydaO E amino acid
HDBIHKAD_02305 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HDBIHKAD_02306 4.8e-144 pstS P Phosphate
HDBIHKAD_02307 1.7e-114 yvyE 3.4.13.9 S YigZ family
HDBIHKAD_02308 4.3e-258 comFA L Helicase C-terminal domain protein
HDBIHKAD_02309 1.2e-105 comFC S Competence protein
HDBIHKAD_02310 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HDBIHKAD_02311 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HDBIHKAD_02312 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HDBIHKAD_02313 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HDBIHKAD_02314 1.5e-132 K response regulator
HDBIHKAD_02315 3.5e-250 phoR 2.7.13.3 T Histidine kinase
HDBIHKAD_02316 1.1e-150 pstS P Phosphate
HDBIHKAD_02317 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
HDBIHKAD_02318 1.5e-155 pstA P Phosphate transport system permease protein PstA
HDBIHKAD_02319 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDBIHKAD_02320 5e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HDBIHKAD_02321 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HDBIHKAD_02322 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HDBIHKAD_02323 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HDBIHKAD_02324 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HDBIHKAD_02325 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HDBIHKAD_02326 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HDBIHKAD_02327 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HDBIHKAD_02328 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HDBIHKAD_02329 3.9e-270 nox C NADH oxidase
HDBIHKAD_02330 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HDBIHKAD_02331 2e-109 yviA S Protein of unknown function (DUF421)
HDBIHKAD_02332 1.1e-61 S Protein of unknown function (DUF3290)
HDBIHKAD_02333 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HDBIHKAD_02334 2.8e-131 yliE T Putative diguanylate phosphodiesterase
HDBIHKAD_02335 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDBIHKAD_02336 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HDBIHKAD_02337 9.2e-212 norA EGP Major facilitator Superfamily
HDBIHKAD_02338 3.6e-117 yfbR S HD containing hydrolase-like enzyme
HDBIHKAD_02339 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HDBIHKAD_02340 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HDBIHKAD_02341 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HDBIHKAD_02342 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HDBIHKAD_02343 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HDBIHKAD_02344 9.3e-87 S Short repeat of unknown function (DUF308)
HDBIHKAD_02345 1.1e-161 rapZ S Displays ATPase and GTPase activities
HDBIHKAD_02346 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HDBIHKAD_02347 3.7e-168 whiA K May be required for sporulation
HDBIHKAD_02348 9.9e-289 oppA E ABC transporter, substratebinding protein
HDBIHKAD_02349 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HDBIHKAD_02350 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HDBIHKAD_02352 4.2e-245 rpoN K Sigma-54 factor, core binding domain
HDBIHKAD_02353 7.3e-189 cggR K Putative sugar-binding domain
HDBIHKAD_02354 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HDBIHKAD_02355 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HDBIHKAD_02356 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HDBIHKAD_02357 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDBIHKAD_02358 2e-131
HDBIHKAD_02359 4.6e-115 clcA P chloride
HDBIHKAD_02360 1.7e-159 clcA P chloride
HDBIHKAD_02361 3.5e-30 secG U Preprotein translocase
HDBIHKAD_02362 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HDBIHKAD_02363 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HDBIHKAD_02364 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HDBIHKAD_02365 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HDBIHKAD_02366 1.5e-256 glnP P ABC transporter
HDBIHKAD_02367 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_02368 6.1e-105 yxjI
HDBIHKAD_02369 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_02370 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HDBIHKAD_02371 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HDBIHKAD_02372 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HDBIHKAD_02373 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HDBIHKAD_02374 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
HDBIHKAD_02375 7.7e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HDBIHKAD_02376 5.6e-161 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HDBIHKAD_02377 6.2e-168 murB 1.3.1.98 M Cell wall formation
HDBIHKAD_02378 0.0 yjcE P Sodium proton antiporter
HDBIHKAD_02379 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_02380 2.1e-120 S Protein of unknown function (DUF1361)
HDBIHKAD_02381 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HDBIHKAD_02382 1.6e-129 ybbR S YbbR-like protein
HDBIHKAD_02383 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HDBIHKAD_02384 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HDBIHKAD_02385 4.5e-123 yliE T EAL domain
HDBIHKAD_02386 3.2e-147 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_02387 3.1e-104 K Bacterial regulatory proteins, tetR family
HDBIHKAD_02388 3.5e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HDBIHKAD_02389 1.5e-52
HDBIHKAD_02390 3e-72
HDBIHKAD_02391 3e-131 1.5.1.39 C nitroreductase
HDBIHKAD_02392 2.2e-100 EGP Transmembrane secretion effector
HDBIHKAD_02393 1.2e-51 L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_02399 5.1e-08
HDBIHKAD_02405 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HDBIHKAD_02406 1.8e-182 P secondary active sulfate transmembrane transporter activity
HDBIHKAD_02407 1.4e-95
HDBIHKAD_02408 2e-94 K Acetyltransferase (GNAT) domain
HDBIHKAD_02409 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
HDBIHKAD_02410 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
HDBIHKAD_02412 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
HDBIHKAD_02413 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDBIHKAD_02414 9.2e-256 mmuP E amino acid
HDBIHKAD_02415 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HDBIHKAD_02416 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_02417 1.6e-121
HDBIHKAD_02418 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HDBIHKAD_02419 5.5e-278 bmr3 EGP Major facilitator Superfamily
HDBIHKAD_02420 3.7e-44 S pyridoxamine 5-phosphate
HDBIHKAD_02421 1.7e-265 npr 1.11.1.1 C NADH oxidase
HDBIHKAD_02422 2.3e-259 ltrA_1 2.7.7.49 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HDBIHKAD_02423 5.9e-103 tnpR L Resolvase, N terminal domain
HDBIHKAD_02424 5.3e-130 S Phage Mu protein F like protein
HDBIHKAD_02425 1.2e-12 ytgB S Transglycosylase associated protein
HDBIHKAD_02426 1.1e-34 lytE M LysM domain protein
HDBIHKAD_02427 3.3e-55 L HTH-like domain
HDBIHKAD_02428 8.4e-224 oxlT P Major Facilitator Superfamily
HDBIHKAD_02429 9.5e-92 L Helix-turn-helix domain
HDBIHKAD_02430 2.5e-76 L HTH-like domain
HDBIHKAD_02431 0.0 uvrA2 L ABC transporter
HDBIHKAD_02432 3e-102 L Resolvase, N terminal domain
HDBIHKAD_02433 1.5e-77 sufB O assembly protein SufB
HDBIHKAD_02434 7.7e-101 yvbG U MarC family integral membrane protein
HDBIHKAD_02436 1.5e-101 tnpR L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HDBIHKAD_02437 4.9e-154 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HDBIHKAD_02438 6.6e-140 cylB V ABC-2 type transporter
HDBIHKAD_02439 4.8e-176 S Bacteriophage abortive infection AbiH
HDBIHKAD_02440 1.5e-46 L Transposase
HDBIHKAD_02441 4.2e-150 S Uncharacterised protein, DegV family COG1307
HDBIHKAD_02442 4.2e-86 M1-874 K Domain of unknown function (DUF1836)
HDBIHKAD_02443 3.2e-119 norB EGP Major Facilitator
HDBIHKAD_02444 3.8e-21
HDBIHKAD_02445 7.8e-19
HDBIHKAD_02447 1.2e-149 D CobQ CobB MinD ParA nucleotide binding domain protein
HDBIHKAD_02448 2.9e-35
HDBIHKAD_02449 2.3e-172 repA S Replication initiator protein A
HDBIHKAD_02450 3.3e-135 S Fic/DOC family
HDBIHKAD_02451 1.1e-41
HDBIHKAD_02452 1.2e-26
HDBIHKAD_02453 3.5e-123
HDBIHKAD_02454 4.1e-59
HDBIHKAD_02455 1.1e-279 lldP C L-lactate permease
HDBIHKAD_02456 3.9e-227
HDBIHKAD_02457 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HDBIHKAD_02458 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HDBIHKAD_02459 6.8e-217 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDBIHKAD_02460 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HDBIHKAD_02461 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HDBIHKAD_02462 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_02463 4.6e-252 gshR1 1.8.1.7 C Glutathione reductase
HDBIHKAD_02464 1.8e-66
HDBIHKAD_02465 6.3e-246 M Glycosyl transferase family group 2
HDBIHKAD_02466 1.2e-39 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDBIHKAD_02467 1.5e-46 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_02468 2e-140 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDBIHKAD_02469 3.2e-15
HDBIHKAD_02470 1e-227 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDBIHKAD_02471 9.6e-47
HDBIHKAD_02472 2.6e-59
HDBIHKAD_02473 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDBIHKAD_02474 7.4e-305 hsdM 2.1.1.72 V type I restriction-modification system
HDBIHKAD_02475 9.3e-95 3.1.21.3 V Type I restriction modification DNA specificity domain
HDBIHKAD_02476 6.1e-43
HDBIHKAD_02477 1.1e-182 L Psort location Cytoplasmic, score
HDBIHKAD_02478 3.1e-26 S Protein of unknown function (DUF3781)
HDBIHKAD_02479 1e-107 ydeA S intracellular protease amidase
HDBIHKAD_02480 2.2e-41 K HxlR-like helix-turn-helix
HDBIHKAD_02481 7.6e-60
HDBIHKAD_02482 1e-64 V ABC transporter
HDBIHKAD_02483 2.3e-51 K Helix-turn-helix domain
HDBIHKAD_02484 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HDBIHKAD_02485 1.4e-46 K Helix-turn-helix domain
HDBIHKAD_02486 1.2e-90 S ABC-2 family transporter protein
HDBIHKAD_02487 2.3e-40 S ABC-2 family transporter protein
HDBIHKAD_02488 9.2e-08 S ABC-2 family transporter protein
HDBIHKAD_02489 4.6e-91 V ABC transporter, ATP-binding protein
HDBIHKAD_02490 8.8e-40
HDBIHKAD_02491 2.3e-32 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDBIHKAD_02492 2e-169 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HDBIHKAD_02493 1.4e-75 2.5.1.105 P Cation efflux family
HDBIHKAD_02494 7.3e-18 czrA K Transcriptional regulator, ArsR family
HDBIHKAD_02495 2.1e-160 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HDBIHKAD_02496 9.5e-107 L Resolvase, N terminal domain
HDBIHKAD_02497 4.2e-115 L hmm pf00665
HDBIHKAD_02498 6.1e-182 1.17.4.1 F Ribonucleotide reductase, small chain
HDBIHKAD_02499 6.1e-171 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HDBIHKAD_02500 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDBIHKAD_02501 4.7e-81 nrdI F NrdI Flavodoxin like
HDBIHKAD_02503 2e-61 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HDBIHKAD_02504 5.6e-95 tnpR1 L Resolvase, N terminal domain
HDBIHKAD_02505 9.8e-39 L Transposase and inactivated derivatives
HDBIHKAD_02506 6.2e-154 L Integrase core domain
HDBIHKAD_02507 4.3e-86 yhbO 3.5.1.124 S Intracellular protease
HDBIHKAD_02508 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HDBIHKAD_02509 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HDBIHKAD_02510 9.5e-213 gntP EG Gluconate
HDBIHKAD_02511 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HDBIHKAD_02512 9.3e-188 yueF S AI-2E family transporter
HDBIHKAD_02513 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HDBIHKAD_02514 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HDBIHKAD_02515 7.8e-48 K sequence-specific DNA binding
HDBIHKAD_02516 2.5e-133 cwlO M NlpC/P60 family
HDBIHKAD_02517 4.1e-106 ygaC J Belongs to the UPF0374 family
HDBIHKAD_02518 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HDBIHKAD_02519 3e-125
HDBIHKAD_02520 6.8e-101 K DNA-templated transcription, initiation
HDBIHKAD_02521 1.3e-25
HDBIHKAD_02522 7e-30
HDBIHKAD_02523 7.3e-33 S Protein of unknown function (DUF2922)
HDBIHKAD_02524 4.7e-82
HDBIHKAD_02526 8.1e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HDBIHKAD_02527 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
HDBIHKAD_02528 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HDBIHKAD_02529 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HDBIHKAD_02530 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HDBIHKAD_02531 9.8e-55 S Enterocin A Immunity
HDBIHKAD_02532 1.9e-258 gor 1.8.1.7 C Glutathione reductase
HDBIHKAD_02533 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HDBIHKAD_02534 2.3e-118 D Alpha beta
HDBIHKAD_02535 2.8e-88
HDBIHKAD_02536 8.1e-102 L Initiator Replication protein
HDBIHKAD_02537 1.3e-79
HDBIHKAD_02539 1.4e-175 S MobA/MobL family
HDBIHKAD_02540 3.6e-115
HDBIHKAD_02541 9.4e-109 L Integrase
HDBIHKAD_02542 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
HDBIHKAD_02543 1e-57 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDBIHKAD_02544 0.0 ybfG M peptidoglycan-binding domain-containing protein
HDBIHKAD_02546 1.7e-84 dps P Belongs to the Dps family
HDBIHKAD_02547 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HDBIHKAD_02548 6.8e-127 yliE T EAL domain
HDBIHKAD_02549 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDBIHKAD_02550 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HDBIHKAD_02551 2e-80
HDBIHKAD_02552 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HDBIHKAD_02553 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDBIHKAD_02554 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HDBIHKAD_02555 4.9e-22
HDBIHKAD_02556 2.9e-70
HDBIHKAD_02557 1.2e-163 K LysR substrate binding domain
HDBIHKAD_02558 2.4e-243 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_02559 8.2e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HDBIHKAD_02560 5.1e-265 S response to antibiotic
HDBIHKAD_02561 2.8e-134 S zinc-ribbon domain
HDBIHKAD_02563 3.2e-37
HDBIHKAD_02564 8.3e-108 aroD S Alpha/beta hydrolase family
HDBIHKAD_02565 1.7e-15 aroD S Alpha/beta hydrolase family
HDBIHKAD_02566 2.6e-176 S Phosphotransferase system, EIIC
HDBIHKAD_02567 2.5e-269 I acetylesterase activity
HDBIHKAD_02568 6.2e-223 sdrF M Collagen binding domain
HDBIHKAD_02569 1.1e-159 yicL EG EamA-like transporter family
HDBIHKAD_02570 4.4e-129 E lipolytic protein G-D-S-L family
HDBIHKAD_02571 1.7e-176 4.1.1.52 S Amidohydrolase
HDBIHKAD_02572 2.5e-112 K Transcriptional regulator C-terminal region
HDBIHKAD_02573 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
HDBIHKAD_02574 4.2e-161 ypbG 2.7.1.2 GK ROK family
HDBIHKAD_02575 0.0 ybfG M peptidoglycan-binding domain-containing protein
HDBIHKAD_02576 5.6e-89
HDBIHKAD_02577 0.0 lmrA 3.6.3.44 V ABC transporter
HDBIHKAD_02578 5e-93 rmaB K Transcriptional regulator, MarR family
HDBIHKAD_02579 7.1e-159 ccpB 5.1.1.1 K lacI family
HDBIHKAD_02580 3e-121 yceE S haloacid dehalogenase-like hydrolase
HDBIHKAD_02581 1.3e-119 drgA C Nitroreductase family
HDBIHKAD_02582 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HDBIHKAD_02583 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
HDBIHKAD_02584 8.7e-155 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HDBIHKAD_02585 1.5e-167 XK27_00670 S ABC transporter
HDBIHKAD_02586 1e-260
HDBIHKAD_02587 7.3e-62
HDBIHKAD_02588 5.1e-190 S Cell surface protein
HDBIHKAD_02589 2.3e-91 S WxL domain surface cell wall-binding
HDBIHKAD_02590 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
HDBIHKAD_02591 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
HDBIHKAD_02592 3.3e-124 livF E ABC transporter
HDBIHKAD_02593 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HDBIHKAD_02594 5.3e-141 livM E Branched-chain amino acid transport system / permease component
HDBIHKAD_02595 2.1e-149 livH U Branched-chain amino acid transport system / permease component
HDBIHKAD_02596 5.4e-212 livJ E Receptor family ligand binding region
HDBIHKAD_02598 7e-33
HDBIHKAD_02599 6.6e-113 zmp3 O Zinc-dependent metalloprotease
HDBIHKAD_02600 2.8e-82 gtrA S GtrA-like protein
HDBIHKAD_02601 1.8e-121 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_02602 1.9e-116 S SNARE associated Golgi protein
HDBIHKAD_02603 2e-49 K Transcriptional regulator, ArsR family
HDBIHKAD_02604 1.2e-95 cadD P Cadmium resistance transporter
HDBIHKAD_02605 0.0 yhcA V ABC transporter, ATP-binding protein
HDBIHKAD_02606 0.0 P Concanavalin A-like lectin/glucanases superfamily
HDBIHKAD_02607 7.4e-64
HDBIHKAD_02608 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
HDBIHKAD_02609 3.2e-55
HDBIHKAD_02610 5.3e-150 dicA K Helix-turn-helix domain
HDBIHKAD_02611 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HDBIHKAD_02612 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HDBIHKAD_02613 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_02614 3.1e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HDBIHKAD_02615 1.4e-184 1.1.1.219 GM Male sterility protein
HDBIHKAD_02616 6.7e-75 K helix_turn_helix, mercury resistance
HDBIHKAD_02617 2.3e-65 M LysM domain
HDBIHKAD_02618 6.7e-87 M Lysin motif
HDBIHKAD_02619 1.8e-107 S SdpI/YhfL protein family
HDBIHKAD_02620 1.8e-54 nudA S ASCH
HDBIHKAD_02621 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
HDBIHKAD_02622 4.2e-92
HDBIHKAD_02623 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
HDBIHKAD_02624 3.3e-219 T diguanylate cyclase
HDBIHKAD_02625 1.2e-73 S Psort location Cytoplasmic, score
HDBIHKAD_02626 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HDBIHKAD_02627 8.6e-218 ykiI
HDBIHKAD_02628 0.0 V ABC transporter
HDBIHKAD_02629 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
HDBIHKAD_02631 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
HDBIHKAD_02632 7.7e-163 IQ KR domain
HDBIHKAD_02634 7.4e-71
HDBIHKAD_02635 4.3e-144 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_02636 9.6e-267 yjeM E Amino Acid
HDBIHKAD_02637 1.1e-65 lysM M LysM domain
HDBIHKAD_02638 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HDBIHKAD_02639 2.1e-213 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HDBIHKAD_02640 0.0 ctpA 3.6.3.54 P P-type ATPase
HDBIHKAD_02641 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDBIHKAD_02642 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HDBIHKAD_02643 3.8e-158 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDBIHKAD_02644 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HDBIHKAD_02645 6e-140 K Helix-turn-helix domain
HDBIHKAD_02646 2.9e-38 S TfoX C-terminal domain
HDBIHKAD_02647 1e-227 hpk9 2.7.13.3 T GHKL domain
HDBIHKAD_02648 8.4e-263
HDBIHKAD_02649 8.4e-75
HDBIHKAD_02650 3.6e-183 S Cell surface protein
HDBIHKAD_02651 1.7e-101 S WxL domain surface cell wall-binding
HDBIHKAD_02653 4.1e-137 S Protease prsW family
HDBIHKAD_02654 2.5e-31
HDBIHKAD_02655 2.7e-23
HDBIHKAD_02656 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HDBIHKAD_02657 1.9e-171 K AI-2E family transporter
HDBIHKAD_02658 1.7e-210 xylR GK ROK family
HDBIHKAD_02659 2.3e-81
HDBIHKAD_02660 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HDBIHKAD_02661 3.9e-162
HDBIHKAD_02662 9.2e-28 padC Q Phenolic acid decarboxylase
HDBIHKAD_02663 2.2e-99 padR K Virulence activator alpha C-term
HDBIHKAD_02664 2.7e-79 T Universal stress protein family
HDBIHKAD_02665 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HDBIHKAD_02666 2.4e-53
HDBIHKAD_02667 1.7e-08
HDBIHKAD_02669 1.9e-57
HDBIHKAD_02670 6e-31 cspA K Cold shock protein
HDBIHKAD_02671 3.8e-40
HDBIHKAD_02672 4.9e-16
HDBIHKAD_02673 2.3e-107 L Integrase
HDBIHKAD_02674 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
HDBIHKAD_02675 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HDBIHKAD_02676 1.2e-51 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HDBIHKAD_02677 3.1e-56 tnp2PF3 L Transposase DDE domain
HDBIHKAD_02678 9.1e-153 cjaA ET ABC transporter substrate-binding protein
HDBIHKAD_02679 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HDBIHKAD_02680 4.3e-113 P ABC transporter permease
HDBIHKAD_02681 4.2e-113 papP P ABC transporter, permease protein
HDBIHKAD_02682 8e-224 hsdM 2.1.1.72 V type I restriction-modification system
HDBIHKAD_02683 2.3e-69 3.1.21.3 V type I restriction modification DNA specificity domain
HDBIHKAD_02684 1.8e-172 L Psort location Cytoplasmic, score
HDBIHKAD_02685 4.8e-18
HDBIHKAD_02686 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HDBIHKAD_02687 8.2e-67
HDBIHKAD_02688 1.3e-148
HDBIHKAD_02689 1.5e-62
HDBIHKAD_02690 5.7e-262 traK U TraM recognition site of TraD and TraG
HDBIHKAD_02691 4.3e-80
HDBIHKAD_02692 1.7e-158 glpQ 3.1.4.46 C phosphodiesterase
HDBIHKAD_02693 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HDBIHKAD_02694 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
HDBIHKAD_02695 8.9e-284 M domain protein
HDBIHKAD_02696 0.0 ydgH S MMPL family
HDBIHKAD_02697 1e-56 T Belongs to the universal stress protein A family
HDBIHKAD_02698 6.7e-250 mntH P H( )-stimulated, divalent metal cation uptake system
HDBIHKAD_02699 1.7e-38 sirR K Helix-turn-helix diphteria tox regulatory element
HDBIHKAD_02701 2.6e-16
HDBIHKAD_02702 4.3e-46 L Transposase
HDBIHKAD_02705 2.3e-34
HDBIHKAD_02706 4.2e-144 soj D AAA domain
HDBIHKAD_02708 1.1e-129 repA S Replication initiator protein A
HDBIHKAD_02711 9.8e-39 L Transposase and inactivated derivatives
HDBIHKAD_02712 1.3e-51 L Integrase core domain
HDBIHKAD_02713 1.1e-84 M1-431 S Protein of unknown function (DUF1706)
HDBIHKAD_02714 1.3e-91 tnpR1 L Resolvase, N terminal domain
HDBIHKAD_02716 5.4e-151 L Integrase core domain
HDBIHKAD_02717 5.9e-218 yifK E Amino acid permease
HDBIHKAD_02718 8.3e-176 L Initiator Replication protein
HDBIHKAD_02719 6.2e-44 S Psort location CytoplasmicMembrane, score
HDBIHKAD_02720 7.3e-21 3.4.21.19 M Belongs to the peptidase S1B family
HDBIHKAD_02721 3.4e-27 S Protein of unknown function (DUF1093)
HDBIHKAD_02722 8.9e-28
HDBIHKAD_02724 7.1e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
HDBIHKAD_02725 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HDBIHKAD_02726 3.4e-106 L Phage integrase family
HDBIHKAD_02727 1.2e-68
HDBIHKAD_02728 5.9e-26 K Transcriptional
HDBIHKAD_02729 5.8e-32
HDBIHKAD_02730 1.6e-56 S SIR2-like domain
HDBIHKAD_02731 5.4e-137 S Domain of unknown function DUF87
HDBIHKAD_02732 3.2e-45 ywfI S Chlorite dismutase
HDBIHKAD_02733 2.3e-246 emrY EGP Major facilitator Superfamily
HDBIHKAD_02734 9.7e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HDBIHKAD_02735 1.3e-274 macB_3 V FtsX-like permease family
HDBIHKAD_02736 8.2e-90 S PAS domain
HDBIHKAD_02738 1.8e-97 S Fic/DOC family
HDBIHKAD_02739 1.1e-41
HDBIHKAD_02740 3.6e-26
HDBIHKAD_02741 0.0 L MobA MobL family protein
HDBIHKAD_02742 4.3e-102 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HDBIHKAD_02743 4e-178 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
HDBIHKAD_02744 2.1e-68 S Protein of unknown function with HXXEE motif
HDBIHKAD_02745 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HDBIHKAD_02746 6.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HDBIHKAD_02747 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HDBIHKAD_02748 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HDBIHKAD_02749 4.8e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HDBIHKAD_02750 1.2e-307 S Protein conserved in bacteria
HDBIHKAD_02751 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HDBIHKAD_02752 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HDBIHKAD_02753 3.6e-58 S Protein of unknown function (DUF1516)
HDBIHKAD_02754 1.9e-89 gtcA S Teichoic acid glycosylation protein
HDBIHKAD_02755 2.1e-180
HDBIHKAD_02756 3.5e-10
HDBIHKAD_02757 5.9e-52
HDBIHKAD_02759 4.3e-30 hol S Bacteriophage holin
HDBIHKAD_02760 2.8e-36 S Haemolysin XhlA
HDBIHKAD_02761 1.9e-201 lys M Glycosyl hydrolases family 25
HDBIHKAD_02762 9.1e-21
HDBIHKAD_02763 6.5e-76
HDBIHKAD_02766 1.4e-115
HDBIHKAD_02767 0.0 S Phage minor structural protein
HDBIHKAD_02768 0.0 S Phage tail protein
HDBIHKAD_02769 0.0 M Phage tail tape measure protein TP901
HDBIHKAD_02770 6.6e-24
HDBIHKAD_02771 2.3e-56 S Phage tail assembly chaperone proteins, TAC
HDBIHKAD_02772 3.5e-104 S Phage tail tube protein
HDBIHKAD_02773 2.1e-56 S Protein of unknown function (DUF806)
HDBIHKAD_02774 4.3e-68 S Bacteriophage HK97-gp10, putative tail-component
HDBIHKAD_02775 1.7e-57 S Phage head-tail joining protein
HDBIHKAD_02776 6.9e-48 S Phage gp6-like head-tail connector protein
HDBIHKAD_02777 3.7e-200 S Phage capsid family
HDBIHKAD_02778 8.7e-123 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HDBIHKAD_02779 2.2e-221 S Phage portal protein
HDBIHKAD_02780 5.6e-26 S Protein of unknown function (DUF1056)
HDBIHKAD_02781 0.0 S Phage Terminase
HDBIHKAD_02782 1e-78 L Phage terminase, small subunit
HDBIHKAD_02784 2.5e-89 L HNH nucleases
HDBIHKAD_02785 8.2e-13 V HNH nucleases
HDBIHKAD_02787 3.6e-76 S Transcriptional regulator, RinA family
HDBIHKAD_02789 4.1e-09
HDBIHKAD_02790 1.9e-28 S YopX protein
HDBIHKAD_02792 1.6e-12
HDBIHKAD_02793 5.9e-26
HDBIHKAD_02796 1.2e-64 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
HDBIHKAD_02797 1.1e-59
HDBIHKAD_02799 4.9e-145 pi346 L IstB-like ATP binding protein
HDBIHKAD_02800 1.6e-71 L DnaD domain protein
HDBIHKAD_02801 3.6e-131 S Putative HNHc nuclease
HDBIHKAD_02802 1.6e-43 S Single-strand binding protein family
HDBIHKAD_02803 9.5e-62 S ERF superfamily
HDBIHKAD_02804 3.3e-81
HDBIHKAD_02806 1.8e-11 S Protein of unknown function (DUF1351)
HDBIHKAD_02808 4.8e-18
HDBIHKAD_02811 2.3e-51 S Domain of unknown function (DUF771)
HDBIHKAD_02813 1.7e-107 S DNA binding
HDBIHKAD_02815 5.3e-37 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_02816 2.4e-16 E IrrE N-terminal-like domain
HDBIHKAD_02817 1.9e-56 kcsA P Ion transport protein
HDBIHKAD_02818 1.9e-30
HDBIHKAD_02824 1.7e-210 S Phage integrase family
HDBIHKAD_02826 0.0 uvrA2 L ABC transporter
HDBIHKAD_02827 7.3e-46
HDBIHKAD_02828 1e-90
HDBIHKAD_02829 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_02830 1.9e-113 S CAAX protease self-immunity
HDBIHKAD_02831 2.5e-59
HDBIHKAD_02832 4.5e-55
HDBIHKAD_02833 1.6e-137 pltR K LytTr DNA-binding domain
HDBIHKAD_02834 7.2e-223 pltK 2.7.13.3 T GHKL domain
HDBIHKAD_02835 1.7e-108
HDBIHKAD_02836 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
HDBIHKAD_02837 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HDBIHKAD_02838 3.5e-117 GM NAD(P)H-binding
HDBIHKAD_02839 1.6e-64 K helix_turn_helix, mercury resistance
HDBIHKAD_02840 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDBIHKAD_02842 4e-176 K LytTr DNA-binding domain
HDBIHKAD_02843 2.3e-156 V ABC transporter
HDBIHKAD_02844 3.4e-124 V Transport permease protein
HDBIHKAD_02846 3.9e-179 XK27_06930 V domain protein
HDBIHKAD_02847 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HDBIHKAD_02848 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HDBIHKAD_02849 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
HDBIHKAD_02850 1.1e-150 ugpE G ABC transporter permease
HDBIHKAD_02851 1.2e-172 ugpA U Binding-protein-dependent transport system inner membrane component
HDBIHKAD_02852 2e-200 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HDBIHKAD_02853 4.1e-84 uspA T Belongs to the universal stress protein A family
HDBIHKAD_02854 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
HDBIHKAD_02855 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HDBIHKAD_02856 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDBIHKAD_02857 1.1e-300 ytgP S Polysaccharide biosynthesis protein
HDBIHKAD_02858 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HDBIHKAD_02859 1.4e-124 3.6.1.27 I Acid phosphatase homologues
HDBIHKAD_02860 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
HDBIHKAD_02861 4.2e-29
HDBIHKAD_02862 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_02863 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HDBIHKAD_02864 0.0 S Pfam Methyltransferase
HDBIHKAD_02865 2.1e-139 N Cell shape-determining protein MreB
HDBIHKAD_02866 1.7e-18 N Cell shape-determining protein MreB
HDBIHKAD_02867 3e-104 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HDBIHKAD_02868 2.6e-25
HDBIHKAD_02869 4.5e-58 XK27_01125 L PFAM IS66 Orf2 family protein
HDBIHKAD_02870 4.9e-160 L Transposase IS66 family
HDBIHKAD_02871 1.5e-115 L Transposase IS66 family
HDBIHKAD_02872 2e-255 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HDBIHKAD_02873 5.5e-198 traA L MobA MobL family protein
HDBIHKAD_02874 4.2e-167 traA L MobA MobL family protein
HDBIHKAD_02875 7.4e-24
HDBIHKAD_02876 1.4e-38
HDBIHKAD_02877 1.3e-87 K Winged helix DNA-binding domain
HDBIHKAD_02878 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HDBIHKAD_02879 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HDBIHKAD_02880 1.8e-27
HDBIHKAD_02881 7.2e-280 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HDBIHKAD_02882 2e-72 mltD CBM50 M PFAM NLP P60 protein
HDBIHKAD_02883 2.5e-53
HDBIHKAD_02884 1.6e-61
HDBIHKAD_02886 9.2e-213 glnA 6.3.1.2 E glutamine synthetase
HDBIHKAD_02887 6e-52 ykoF S YKOF-related Family
HDBIHKAD_02888 6.4e-46 M domain protein
HDBIHKAD_02889 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
HDBIHKAD_02890 1.1e-95 tnp L DDE domain
HDBIHKAD_02891 4e-151 glcU U sugar transport
HDBIHKAD_02892 0.0 yhcA V MacB-like periplasmic core domain
HDBIHKAD_02893 1.4e-81
HDBIHKAD_02894 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HDBIHKAD_02895 1.5e-77 elaA S Acetyltransferase (GNAT) domain
HDBIHKAD_02898 1.9e-31
HDBIHKAD_02899 4.8e-244 dinF V MatE
HDBIHKAD_02900 1.5e-47 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDBIHKAD_02901 5.8e-36
HDBIHKAD_02902 1.5e-33
HDBIHKAD_02903 2.3e-36 KLT serine threonine protein kinase
HDBIHKAD_02904 1.3e-104 L Psort location Cytoplasmic, score
HDBIHKAD_02906 1.2e-145 U TraM recognition site of TraD and TraG
HDBIHKAD_02908 3.7e-51 S Protein of unknown function (DUF975)
HDBIHKAD_02909 7.4e-95 tnpR1 L Resolvase, N terminal domain
HDBIHKAD_02911 7.8e-146 D CobQ CobB MinD ParA nucleotide binding domain protein
HDBIHKAD_02912 2.1e-58 S Family of unknown function (DUF5388)
HDBIHKAD_02913 4.6e-59 norB EGP Major Facilitator
HDBIHKAD_02915 6.7e-173 ybfG M peptidoglycan-binding domain-containing protein
HDBIHKAD_02916 1.9e-74 L Transposase DDE domain
HDBIHKAD_02917 7.4e-67 L Putative transposase of IS4/5 family (DUF4096)
HDBIHKAD_02918 4.4e-19
HDBIHKAD_02919 6.2e-50
HDBIHKAD_02920 1.7e-63 K Helix-turn-helix XRE-family like proteins
HDBIHKAD_02921 7.6e-110 XK27_07075 V CAAX protease self-immunity
HDBIHKAD_02922 1.1e-56 hxlR K HxlR-like helix-turn-helix
HDBIHKAD_02923 1.5e-129 L Helix-turn-helix domain
HDBIHKAD_02924 1.7e-159 L hmm pf00665
HDBIHKAD_02925 6.7e-232 EGP Major facilitator Superfamily
HDBIHKAD_02927 2.7e-99 K Primase C terminal 1 (PriCT-1)
HDBIHKAD_02928 1.6e-39 soj D PFAM Cobyrinic acid a,c-diamide synthase
HDBIHKAD_02930 2e-174 L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_02931 1.5e-197 cycA E Amino acid permease
HDBIHKAD_02932 7.7e-57 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDBIHKAD_02933 1.4e-24 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HDBIHKAD_02934 4.7e-20 lacA 3.2.1.23 G -beta-galactosidase
HDBIHKAD_02935 1.9e-64 lacA 3.2.1.23 G -beta-galactosidase
HDBIHKAD_02936 3.4e-219 lacA 3.2.1.23 G -beta-galactosidase
HDBIHKAD_02937 0.0 lacS G Transporter
HDBIHKAD_02938 2.6e-71 brnQ U Component of the transport system for branched-chain amino acids
HDBIHKAD_02939 8.9e-11 S Domain of unknown function (DUF4355)
HDBIHKAD_02940 6.8e-57 S Domain of unknown function (DUF4355)
HDBIHKAD_02941 1.3e-81 gpG
HDBIHKAD_02942 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HDBIHKAD_02944 2.7e-143 D CobQ CobB MinD ParA nucleotide binding domain protein
HDBIHKAD_02946 1.1e-64 padC Q Phenolic acid decarboxylase
HDBIHKAD_02947 6.7e-142 tesE Q hydratase
HDBIHKAD_02948 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HDBIHKAD_02949 2.8e-157 degV S DegV family
HDBIHKAD_02950 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HDBIHKAD_02951 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HDBIHKAD_02953 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HDBIHKAD_02954 1.1e-302
HDBIHKAD_02956 3e-158 S Bacterial protein of unknown function (DUF916)
HDBIHKAD_02957 5.9e-92 S Cell surface protein
HDBIHKAD_02958 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HDBIHKAD_02959 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HDBIHKAD_02960 9.1e-109 jag S R3H domain protein
HDBIHKAD_02961 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
HDBIHKAD_02962 1e-309 E ABC transporter, substratebinding protein
HDBIHKAD_02963 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HDBIHKAD_02964 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HDBIHKAD_02965 4.5e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HDBIHKAD_02966 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HDBIHKAD_02967 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HDBIHKAD_02968 5e-37 yaaA S S4 domain protein YaaA
HDBIHKAD_02969 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HDBIHKAD_02970 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDBIHKAD_02971 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HDBIHKAD_02972 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HDBIHKAD_02973 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HDBIHKAD_02974 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HDBIHKAD_02975 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HDBIHKAD_02976 1.4e-67 rplI J Binds to the 23S rRNA
HDBIHKAD_02977 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HDBIHKAD_02978 8.8e-226 yttB EGP Major facilitator Superfamily
HDBIHKAD_02979 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HDBIHKAD_02980 5.6e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HDBIHKAD_02982 4.2e-276 E ABC transporter, substratebinding protein
HDBIHKAD_02983 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HDBIHKAD_02984 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HDBIHKAD_02985 7e-196 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HDBIHKAD_02986 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HDBIHKAD_02987 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HDBIHKAD_02988 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HDBIHKAD_02990 4.5e-143 S haloacid dehalogenase-like hydrolase
HDBIHKAD_02991 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDBIHKAD_02992 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HDBIHKAD_02993 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
HDBIHKAD_02994 1.6e-31 cspA K Cold shock protein domain
HDBIHKAD_02995 1.7e-37
HDBIHKAD_02997 6.2e-131 K response regulator
HDBIHKAD_02998 0.0 vicK 2.7.13.3 T Histidine kinase
HDBIHKAD_02999 1.2e-244 yycH S YycH protein
HDBIHKAD_03000 2.2e-151 yycI S YycH protein
HDBIHKAD_03001 8.9e-158 vicX 3.1.26.11 S domain protein
HDBIHKAD_03002 6.8e-173 htrA 3.4.21.107 O serine protease
HDBIHKAD_03003 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HDBIHKAD_03004 1.5e-95 K Bacterial regulatory proteins, tetR family
HDBIHKAD_03005 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HDBIHKAD_03006 1.5e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HDBIHKAD_03007 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HDBIHKAD_03008 4.2e-32 pnb C nitroreductase
HDBIHKAD_03009 2.8e-66 pnb C nitroreductase
HDBIHKAD_03010 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HDBIHKAD_03011 2.6e-115 S Elongation factor G-binding protein, N-terminal
HDBIHKAD_03012 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HDBIHKAD_03013 1.6e-258 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_03014 5.7e-158 K LysR family
HDBIHKAD_03015 1e-72 C FMN binding
HDBIHKAD_03016 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HDBIHKAD_03017 2.3e-164 ptlF S KR domain
HDBIHKAD_03018 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HDBIHKAD_03019 1.3e-122 drgA C Nitroreductase family
HDBIHKAD_03020 1.3e-290 QT PucR C-terminal helix-turn-helix domain
HDBIHKAD_03021 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDBIHKAD_03022 3.3e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HDBIHKAD_03023 7.4e-250 yjjP S Putative threonine/serine exporter
HDBIHKAD_03024 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
HDBIHKAD_03025 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HDBIHKAD_03026 2.9e-81 6.3.3.2 S ASCH
HDBIHKAD_03027 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HDBIHKAD_03028 5.5e-172 yobV1 K WYL domain
HDBIHKAD_03029 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HDBIHKAD_03030 0.0 tetP J elongation factor G
HDBIHKAD_03031 8.2e-39 S Protein of unknown function
HDBIHKAD_03032 2.1e-61 S Protein of unknown function
HDBIHKAD_03033 3.6e-152 EG EamA-like transporter family
HDBIHKAD_03034 3.6e-93 MA20_25245 K FR47-like protein
HDBIHKAD_03035 2e-126 hchA S DJ-1/PfpI family
HDBIHKAD_03036 5.4e-181 1.1.1.1 C nadph quinone reductase
HDBIHKAD_03037 1.9e-47 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_03038 2.3e-235 mepA V MATE efflux family protein
HDBIHKAD_03039 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HDBIHKAD_03040 1.6e-140 S Belongs to the UPF0246 family
HDBIHKAD_03041 6e-76
HDBIHKAD_03042 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HDBIHKAD_03043 9.2e-131 znuB U ABC 3 transport family
HDBIHKAD_03044 9.8e-129 fhuC 3.6.3.35 P ABC transporter
HDBIHKAD_03045 1.3e-181 S Prolyl oligopeptidase family
HDBIHKAD_03046 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HDBIHKAD_03047 3.2e-37 veg S Biofilm formation stimulator VEG
HDBIHKAD_03048 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HDBIHKAD_03049 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HDBIHKAD_03050 5.7e-146 tatD L hydrolase, TatD family
HDBIHKAD_03051 8.4e-70 nrdI F NrdI Flavodoxin like
HDBIHKAD_03052 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HDBIHKAD_03053 4.1e-159 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HDBIHKAD_03054 9.4e-175 1.17.4.1 F Ribonucleotide reductase, small chain
HDBIHKAD_03055 1.2e-45 K Bacterial regulatory proteins, tetR family
HDBIHKAD_03056 3.6e-97 tnpR1 L Resolvase, N terminal domain
HDBIHKAD_03057 1.1e-54 L recombinase activity
HDBIHKAD_03059 3.4e-191 L Transposase and inactivated derivatives, IS30 family
HDBIHKAD_03060 2.7e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_03061 0.0 cadA 3.6.3.3, 3.6.3.5 P Cadmium transporter
HDBIHKAD_03062 1.7e-24 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDBIHKAD_03063 4.8e-48 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HDBIHKAD_03064 3.3e-240 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_03065 2.2e-302 1.3.5.4 C FMN_bind
HDBIHKAD_03066 5.4e-132 K LysR family
HDBIHKAD_03067 7.9e-60 mleR K LysR substrate binding domain
HDBIHKAD_03068 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
HDBIHKAD_03069 9.8e-28
HDBIHKAD_03070 1.6e-39 L Transposase
HDBIHKAD_03071 4.4e-130 S haloacid dehalogenase-like hydrolase
HDBIHKAD_03072 7.7e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HDBIHKAD_03073 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HDBIHKAD_03074 1.5e-178 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HDBIHKAD_03075 2.5e-32 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
HDBIHKAD_03076 9.6e-144 cdr P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDBIHKAD_03077 8.4e-199 L Psort location Cytoplasmic, score
HDBIHKAD_03078 2e-166 GM NmrA-like family
HDBIHKAD_03079 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HDBIHKAD_03080 0.0 M Glycosyl hydrolases family 25
HDBIHKAD_03081 2.2e-177 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HDBIHKAD_03082 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
HDBIHKAD_03083 3e-13 S YozE SAM-like fold
HDBIHKAD_03084 1.5e-22
HDBIHKAD_03085 9.4e-133 ywqE 3.1.3.48 GM PHP domain protein
HDBIHKAD_03086 1.6e-129 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HDBIHKAD_03087 7.2e-125 epsB M biosynthesis protein
HDBIHKAD_03088 2.2e-38 L Transposase and inactivated derivatives
HDBIHKAD_03089 1.2e-09 S YozE SAM-like fold
HDBIHKAD_03090 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HDBIHKAD_03091 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HDBIHKAD_03092 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HDBIHKAD_03093 2.3e-176 K Transcriptional regulator
HDBIHKAD_03094 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDBIHKAD_03095 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HDBIHKAD_03096 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HDBIHKAD_03097 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
HDBIHKAD_03098 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HDBIHKAD_03099 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HDBIHKAD_03100 2.6e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HDBIHKAD_03101 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HDBIHKAD_03102 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HDBIHKAD_03103 3.3e-158 dprA LU DNA protecting protein DprA
HDBIHKAD_03104 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HDBIHKAD_03105 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HDBIHKAD_03107 6.8e-228 XK27_05470 E Methionine synthase
HDBIHKAD_03108 3.1e-170 cpsY K Transcriptional regulator, LysR family
HDBIHKAD_03109 2.3e-173 L restriction endonuclease
HDBIHKAD_03110 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HDBIHKAD_03111 5.7e-197 XK27_00915 C Luciferase-like monooxygenase
HDBIHKAD_03112 7.3e-251 emrY EGP Major facilitator Superfamily
HDBIHKAD_03113 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HDBIHKAD_03114 3.4e-35 yozE S Belongs to the UPF0346 family
HDBIHKAD_03115 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HDBIHKAD_03116 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
HDBIHKAD_03117 5.1e-148 DegV S EDD domain protein, DegV family
HDBIHKAD_03118 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HDBIHKAD_03119 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HDBIHKAD_03120 0.0 yfmR S ABC transporter, ATP-binding protein
HDBIHKAD_03121 9.6e-85
HDBIHKAD_03122 2.3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HDBIHKAD_03123 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HDBIHKAD_03124 1.3e-148 3.1.3.102, 3.1.3.104 S hydrolase
HDBIHKAD_03125 2.1e-206 S Tetratricopeptide repeat protein
HDBIHKAD_03126 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HDBIHKAD_03127 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HDBIHKAD_03128 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HDBIHKAD_03129 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HDBIHKAD_03130 2e-19 M Lysin motif
HDBIHKAD_03131 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HDBIHKAD_03132 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
HDBIHKAD_03133 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HDBIHKAD_03134 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HDBIHKAD_03135 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HDBIHKAD_03136 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HDBIHKAD_03137 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HDBIHKAD_03138 1.1e-164 xerD D recombinase XerD
HDBIHKAD_03139 1.1e-169 cvfB S S1 domain
HDBIHKAD_03140 1.5e-74 yeaL S Protein of unknown function (DUF441)
HDBIHKAD_03141 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HDBIHKAD_03142 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HDBIHKAD_03143 0.0 dnaE 2.7.7.7 L DNA polymerase
HDBIHKAD_03144 5.6e-29 S Protein of unknown function (DUF2929)
HDBIHKAD_03146 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDBIHKAD_03147 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HDBIHKAD_03148 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HDBIHKAD_03149 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HDBIHKAD_03150 6.9e-223 M O-Antigen ligase
HDBIHKAD_03151 2e-119 drrB U ABC-2 type transporter
HDBIHKAD_03152 3.2e-167 drrA V ABC transporter
HDBIHKAD_03153 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_03154 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HDBIHKAD_03155 7.8e-61 P Rhodanese Homology Domain
HDBIHKAD_03156 4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HDBIHKAD_03157 1.7e-207
HDBIHKAD_03158 7.4e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
HDBIHKAD_03159 2.6e-180 C Zinc-binding dehydrogenase
HDBIHKAD_03160 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HDBIHKAD_03161 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HDBIHKAD_03162 2.2e-241 EGP Major facilitator Superfamily
HDBIHKAD_03163 4.3e-77 K Transcriptional regulator
HDBIHKAD_03164 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HDBIHKAD_03165 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HDBIHKAD_03166 8e-137 K DeoR C terminal sensor domain
HDBIHKAD_03167 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HDBIHKAD_03168 9.1e-71 yneH 1.20.4.1 P ArsC family
HDBIHKAD_03169 4.1e-68 S Protein of unknown function (DUF1722)
HDBIHKAD_03170 3.5e-106 GM epimerase
HDBIHKAD_03171 0.0 CP_1020 S Zinc finger, swim domain protein
HDBIHKAD_03172 4.1e-82 K Bacterial regulatory proteins, tetR family
HDBIHKAD_03173 4.7e-214 S membrane
HDBIHKAD_03174 1.6e-14 K Bacterial regulatory proteins, tetR family
HDBIHKAD_03175 3.4e-72 S Alpha/beta hydrolase of unknown function (DUF915)
HDBIHKAD_03176 2.8e-22 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HDBIHKAD_03177 1.7e-52
HDBIHKAD_03178 5.1e-238 EGP Major Facilitator Superfamily
HDBIHKAD_03179 0.0 mco Q Multicopper oxidase
HDBIHKAD_03180 4.7e-25
HDBIHKAD_03182 6.1e-29
HDBIHKAD_03183 3.3e-99 V ATPase associated with various cellular activities
HDBIHKAD_03184 7.3e-224 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HDBIHKAD_03185 2.6e-61 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HDBIHKAD_03186 4.5e-54 L Transposase
HDBIHKAD_03187 3.9e-136 L Replication protein
HDBIHKAD_03188 3.9e-136 L Replication protein
HDBIHKAD_03189 1.1e-193 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HDBIHKAD_03190 6.5e-290 clcA P chloride
HDBIHKAD_03191 1.4e-17 ytgB S Transglycosylase associated protein
HDBIHKAD_03192 3.7e-241 iolT EGP Major facilitator Superfamily
HDBIHKAD_03193 2e-162 yxaB GM Polysaccharide pyruvyl transferase
HDBIHKAD_03194 1.8e-80 EGP Major facilitator Superfamily
HDBIHKAD_03195 7.4e-75 rfbP M Bacterial sugar transferase
HDBIHKAD_03196 2.5e-61 cpsF M Oligosaccharide biosynthesis protein Alg14 like
HDBIHKAD_03197 2.3e-23 pssE S Glycosyltransferase family 28 C-terminal domain
HDBIHKAD_03198 3e-27 2.7.8.12 M Glycosyltransferase sugar-binding region containing DXD motif
HDBIHKAD_03199 2.1e-221 S Calcineurin-like phosphoesterase
HDBIHKAD_03200 7.1e-56 asnB 6.3.5.4 E Asparagine synthase
HDBIHKAD_03201 6.2e-41 KLT serine threonine protein kinase
HDBIHKAD_03202 2e-33
HDBIHKAD_03203 1.7e-35
HDBIHKAD_03204 5.7e-47 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HDBIHKAD_03205 8e-18
HDBIHKAD_03206 1.5e-55 XK27_01125 L PFAM IS66 Orf2 family protein
HDBIHKAD_03207 3.7e-24
HDBIHKAD_03208 7.3e-194 pbuX F xanthine permease
HDBIHKAD_03209 7.2e-100 K Primase C terminal 1 (PriCT-1)
HDBIHKAD_03210 7.2e-197 K Helix-turn-helix domain
HDBIHKAD_03211 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HDBIHKAD_03212 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HDBIHKAD_03213 4.1e-53 yitW S Iron-sulfur cluster assembly protein
HDBIHKAD_03214 1.8e-53 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_03215 2.1e-160 P Sodium:sulfate symporter transmembrane region
HDBIHKAD_03216 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HDBIHKAD_03217 2.6e-183 aroF 2.5.1.54 E DAHP synthetase I family
HDBIHKAD_03218 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HDBIHKAD_03219 8.5e-44 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDBIHKAD_03220 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HDBIHKAD_03221 2.5e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HDBIHKAD_03222 2.2e-173 ywhK S Membrane
HDBIHKAD_03223 4e-164 degV S Uncharacterised protein, DegV family COG1307
HDBIHKAD_03224 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HDBIHKAD_03225 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HDBIHKAD_03226 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HDBIHKAD_03227 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDBIHKAD_03228 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDBIHKAD_03229 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HDBIHKAD_03230 9.8e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HDBIHKAD_03231 3.5e-142 cad S FMN_bind
HDBIHKAD_03232 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HDBIHKAD_03233 7.2e-86 ynhH S NusG domain II
HDBIHKAD_03234 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HDBIHKAD_03235 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HDBIHKAD_03236 2.1e-61 rplQ J Ribosomal protein L17
HDBIHKAD_03237 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDBIHKAD_03238 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HDBIHKAD_03239 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HDBIHKAD_03240 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HDBIHKAD_03241 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HDBIHKAD_03242 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HDBIHKAD_03243 6.3e-70 rplO J Binds to the 23S rRNA
HDBIHKAD_03244 2.2e-24 rpmD J Ribosomal protein L30
HDBIHKAD_03245 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HDBIHKAD_03246 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HDBIHKAD_03247 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HDBIHKAD_03248 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HDBIHKAD_03249 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HDBIHKAD_03250 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HDBIHKAD_03251 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HDBIHKAD_03252 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HDBIHKAD_03253 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HDBIHKAD_03254 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HDBIHKAD_03255 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HDBIHKAD_03256 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HDBIHKAD_03257 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HDBIHKAD_03258 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HDBIHKAD_03259 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HDBIHKAD_03260 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HDBIHKAD_03261 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HDBIHKAD_03262 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HDBIHKAD_03263 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HDBIHKAD_03264 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HDBIHKAD_03265 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HDBIHKAD_03266 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HDBIHKAD_03267 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDBIHKAD_03268 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HDBIHKAD_03269 1.5e-109 K Bacterial regulatory proteins, tetR family
HDBIHKAD_03270 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HDBIHKAD_03271 6.9e-78 ctsR K Belongs to the CtsR family
HDBIHKAD_03279 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HDBIHKAD_03280 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HDBIHKAD_03281 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HDBIHKAD_03282 1.6e-263 lysP E amino acid
HDBIHKAD_03283 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HDBIHKAD_03284 3.6e-91 K Transcriptional regulator
HDBIHKAD_03285 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HDBIHKAD_03286 2e-154 I alpha/beta hydrolase fold
HDBIHKAD_03287 3.9e-119 lssY 3.6.1.27 I phosphatase
HDBIHKAD_03288 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HDBIHKAD_03289 2.2e-76 S Threonine/Serine exporter, ThrE
HDBIHKAD_03290 1.5e-130 thrE S Putative threonine/serine exporter
HDBIHKAD_03291 6e-31 cspC K Cold shock protein
HDBIHKAD_03292 2e-120 sirR K iron dependent repressor
HDBIHKAD_03293 2.6e-58
HDBIHKAD_03294 1.7e-84 merR K MerR HTH family regulatory protein
HDBIHKAD_03295 4.8e-91 lmrB EGP Major facilitator Superfamily

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)