ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCIGHHLN_00001 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCIGHHLN_00002 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIGHHLN_00003 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HCIGHHLN_00004 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCIGHHLN_00005 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCIGHHLN_00006 2.2e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCIGHHLN_00007 3.1e-74 yabR J RNA binding
HCIGHHLN_00008 1.1e-63 divIC D Septum formation initiator
HCIGHHLN_00010 2.2e-42 yabO J S4 domain protein
HCIGHHLN_00011 3.3e-289 yabM S Polysaccharide biosynthesis protein
HCIGHHLN_00012 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCIGHHLN_00013 4.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCIGHHLN_00014 1e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCIGHHLN_00015 1.4e-264 S Putative peptidoglycan binding domain
HCIGHHLN_00016 2.1e-114 S (CBS) domain
HCIGHHLN_00017 4.1e-84 S QueT transporter
HCIGHHLN_00018 9.4e-189 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCIGHHLN_00019 1.9e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine
HCIGHHLN_00020 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
HCIGHHLN_00021 6.9e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCIGHHLN_00022 2.7e-188 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCIGHHLN_00023 7.5e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCIGHHLN_00024 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCIGHHLN_00025 0.0 kup P Transport of potassium into the cell
HCIGHHLN_00026 2.3e-63 ndoA L Toxic component of a toxin-antitoxin (TA) module
HCIGHHLN_00027 1.7e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCIGHHLN_00028 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCIGHHLN_00029 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HCIGHHLN_00030 5.6e-261 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCIGHHLN_00031 2e-146
HCIGHHLN_00032 2.1e-139 htpX O Belongs to the peptidase M48B family
HCIGHHLN_00033 1.7e-91 lemA S LemA family
HCIGHHLN_00034 9.2e-127 srtA 3.4.22.70 M sortase family
HCIGHHLN_00035 3.2e-214 J translation release factor activity
HCIGHHLN_00036 7.8e-41 rpmE2 J Ribosomal protein L31
HCIGHHLN_00037 3e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCIGHHLN_00038 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIGHHLN_00039 2.5e-26
HCIGHHLN_00040 6.4e-131 S YheO-like PAS domain
HCIGHHLN_00041 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HCIGHHLN_00042 3.7e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HCIGHHLN_00043 3.1e-229 tdcC E amino acid
HCIGHHLN_00044 1.8e-245 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCIGHHLN_00045 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCIGHHLN_00046 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HCIGHHLN_00047 3.8e-78 ywiB S Domain of unknown function (DUF1934)
HCIGHHLN_00048 1.3e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HCIGHHLN_00049 9e-264 ywfO S HD domain protein
HCIGHHLN_00050 6.4e-148 yxeH S hydrolase
HCIGHHLN_00051 4.1e-125
HCIGHHLN_00052 2.5e-181 S DUF218 domain
HCIGHHLN_00053 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCIGHHLN_00054 2.2e-151 bla1 3.5.2.6 V Beta-lactamase enzyme family
HCIGHHLN_00055 3.6e-207 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCIGHHLN_00056 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HCIGHHLN_00057 2.1e-31
HCIGHHLN_00058 1.7e-43 ankB S ankyrin repeats
HCIGHHLN_00059 6.7e-12 T Pre-toxin TG
HCIGHHLN_00060 9.2e-131 znuB U ABC 3 transport family
HCIGHHLN_00061 9.8e-129 fhuC 3.6.3.35 P ABC transporter
HCIGHHLN_00062 5.1e-181 S Prolyl oligopeptidase family
HCIGHHLN_00063 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCIGHHLN_00064 3.2e-37 veg S Biofilm formation stimulator VEG
HCIGHHLN_00065 8.8e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCIGHHLN_00066 2.3e-96 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HCIGHHLN_00067 5.7e-146 tatD L hydrolase, TatD family
HCIGHHLN_00068 1.6e-211 bcr1 EGP Major facilitator Superfamily
HCIGHHLN_00069 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCIGHHLN_00070 1.8e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
HCIGHHLN_00071 2e-160 yunF F Protein of unknown function DUF72
HCIGHHLN_00072 3.9e-133 cobB K SIR2 family
HCIGHHLN_00073 3.1e-178
HCIGHHLN_00074 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HCIGHHLN_00075 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCIGHHLN_00076 7.9e-151 S Psort location Cytoplasmic, score
HCIGHHLN_00077 2.9e-207
HCIGHHLN_00078 3.1e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIGHHLN_00079 5.3e-133 K Helix-turn-helix domain, rpiR family
HCIGHHLN_00080 1e-162 GK ROK family
HCIGHHLN_00081 7.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_00082 3.3e-250 chbC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00083 1.4e-74 S Domain of unknown function (DUF3284)
HCIGHHLN_00084 3.9e-24
HCIGHHLN_00085 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00086 9e-130 K UbiC transcription regulator-associated domain protein
HCIGHHLN_00087 2.6e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCIGHHLN_00088 1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
HCIGHHLN_00089 0.0 helD 3.6.4.12 L DNA helicase
HCIGHHLN_00090 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
HCIGHHLN_00091 6.9e-36 S RelE-like toxin of type II toxin-antitoxin system HigB
HCIGHHLN_00092 1.9e-113 S CAAX protease self-immunity
HCIGHHLN_00093 6.4e-109 V CAAX protease self-immunity
HCIGHHLN_00094 9.7e-118 ypbD S CAAX protease self-immunity
HCIGHHLN_00095 1.2e-107 S CAAX protease self-immunity
HCIGHHLN_00096 8.9e-243 mesE M Transport protein ComB
HCIGHHLN_00097 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HCIGHHLN_00098 6.7e-23
HCIGHHLN_00099 6.9e-22 plnF
HCIGHHLN_00100 4.8e-129 S CAAX protease self-immunity
HCIGHHLN_00101 1e-131 plnD K LytTr DNA-binding domain
HCIGHHLN_00102 1.9e-130 plnC K LytTr DNA-binding domain
HCIGHHLN_00103 3.9e-227 plnB 2.7.13.3 T GHKL domain
HCIGHHLN_00104 4.3e-18 plnA
HCIGHHLN_00105 8.4e-27
HCIGHHLN_00106 7e-117 plnP S CAAX protease self-immunity
HCIGHHLN_00107 3.9e-226 M Glycosyl transferase family 2
HCIGHHLN_00109 2.8e-28
HCIGHHLN_00110 3.5e-24 plnJ
HCIGHHLN_00111 5.2e-23 plnK
HCIGHHLN_00112 1.7e-117
HCIGHHLN_00113 2.9e-17 plnR
HCIGHHLN_00114 7.2e-32
HCIGHHLN_00116 2.1e-208 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCIGHHLN_00117 3.2e-256 brnQ U Component of the transport system for branched-chain amino acids
HCIGHHLN_00118 1.4e-150 S hydrolase
HCIGHHLN_00119 3.3e-166 K Transcriptional regulator
HCIGHHLN_00120 6.9e-147 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_00121 4.8e-197 uhpT EGP Major facilitator Superfamily
HCIGHHLN_00122 9.6e-120 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCIGHHLN_00123 2.4e-38
HCIGHHLN_00124 5.6e-68 S Immunity protein 63
HCIGHHLN_00125 1.2e-64
HCIGHHLN_00126 1.7e-39
HCIGHHLN_00127 6.5e-33
HCIGHHLN_00128 1.4e-175
HCIGHHLN_00129 7.6e-26 M dTDP-4-dehydrorhamnose reductase activity
HCIGHHLN_00130 0.0 M domain protein
HCIGHHLN_00131 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_00132 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
HCIGHHLN_00133 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCIGHHLN_00134 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
HCIGHHLN_00135 9.9e-180 proV E ABC transporter, ATP-binding protein
HCIGHHLN_00136 1.8e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCIGHHLN_00137 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
HCIGHHLN_00138 3.3e-161 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_00139 4.5e-174 rihC 3.2.2.1 F Nucleoside
HCIGHHLN_00140 1.4e-69 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCIGHHLN_00141 9.3e-80
HCIGHHLN_00142 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HCIGHHLN_00143 4.7e-232 flhF N Uncharacterized conserved protein (DUF2075)
HCIGHHLN_00144 2e-94 yxkA S Phosphatidylethanolamine-binding protein
HCIGHHLN_00145 1.1e-54 ypaA S Protein of unknown function (DUF1304)
HCIGHHLN_00146 5.4e-310 mco Q Multicopper oxidase
HCIGHHLN_00147 7.2e-121 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HCIGHHLN_00148 6.3e-102 zmp1 O Zinc-dependent metalloprotease
HCIGHHLN_00149 3.7e-44
HCIGHHLN_00150 5.4e-178 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCIGHHLN_00151 2.3e-240 amtB P ammonium transporter
HCIGHHLN_00152 2.1e-258 P Major Facilitator Superfamily
HCIGHHLN_00153 3.7e-85 K Transcriptional regulator PadR-like family
HCIGHHLN_00154 8.4e-44
HCIGHHLN_00155 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HCIGHHLN_00156 3.5e-154 tagG U Transport permease protein
HCIGHHLN_00157 2.2e-218
HCIGHHLN_00158 4.2e-225 mtnE 2.6.1.83 E Aminotransferase
HCIGHHLN_00159 7.7e-148 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIGHHLN_00160 1.1e-86 metI U Binding-protein-dependent transport system inner membrane component
HCIGHHLN_00161 1.1e-125 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCIGHHLN_00162 2.2e-111 metQ P NLPA lipoprotein
HCIGHHLN_00163 2.8e-60 S CHY zinc finger
HCIGHHLN_00164 1.4e-178 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCIGHHLN_00165 6.8e-96 bioY S BioY family
HCIGHHLN_00166 3e-40
HCIGHHLN_00167 1.7e-281 pipD E Dipeptidase
HCIGHHLN_00168 3e-30
HCIGHHLN_00169 3e-122 qmcA O prohibitin homologues
HCIGHHLN_00170 2.3e-240 xylP1 G MFS/sugar transport protein
HCIGHHLN_00172 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HCIGHHLN_00173 1.1e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
HCIGHHLN_00174 1.9e-189
HCIGHHLN_00175 2e-163 ytrB V ABC transporter
HCIGHHLN_00176 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HCIGHHLN_00177 8.1e-22
HCIGHHLN_00178 8e-91 K acetyltransferase
HCIGHHLN_00179 1e-84 K GNAT family
HCIGHHLN_00180 1.1e-83 6.3.3.2 S ASCH
HCIGHHLN_00181 8.5e-96 puuR K Cupin domain
HCIGHHLN_00182 1.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HCIGHHLN_00183 2e-149 potB P ABC transporter permease
HCIGHHLN_00184 3.4e-141 potC P ABC transporter permease
HCIGHHLN_00185 4e-206 potD P ABC transporter
HCIGHHLN_00186 7.1e-21 U Preprotein translocase subunit SecB
HCIGHHLN_00187 2.2e-30
HCIGHHLN_00188 9.4e-08 S Motility quorum-sensing regulator, toxin of MqsA
HCIGHHLN_00189 3.1e-38
HCIGHHLN_00190 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
HCIGHHLN_00191 1.7e-75 K Transcriptional regulator
HCIGHHLN_00192 5e-78 elaA S GNAT family
HCIGHHLN_00193 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIGHHLN_00194 6.8e-57
HCIGHHLN_00195 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HCIGHHLN_00196 3.7e-131
HCIGHHLN_00197 5.7e-177 sepS16B
HCIGHHLN_00198 2.2e-66 gcvH E Glycine cleavage H-protein
HCIGHHLN_00199 1.2e-29 lytE M LysM domain protein
HCIGHHLN_00200 1.7e-52 M Lysin motif
HCIGHHLN_00201 4.5e-121 S CAAX protease self-immunity
HCIGHHLN_00202 2.5e-114 V CAAX protease self-immunity
HCIGHHLN_00203 7.1e-121 yclH V ABC transporter
HCIGHHLN_00204 1.7e-194 yclI V MacB-like periplasmic core domain
HCIGHHLN_00205 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HCIGHHLN_00206 1e-107 tag 3.2.2.20 L glycosylase
HCIGHHLN_00207 0.0 ydgH S MMPL family
HCIGHHLN_00208 3.1e-104 K transcriptional regulator
HCIGHHLN_00209 2.7e-123 2.7.6.5 S RelA SpoT domain protein
HCIGHHLN_00210 1.3e-47
HCIGHHLN_00211 2e-258 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
HCIGHHLN_00212 1.4e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCIGHHLN_00213 2.1e-41
HCIGHHLN_00214 1.7e-56
HCIGHHLN_00215 7.3e-242 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00216 1e-128 yidA K Helix-turn-helix domain, rpiR family
HCIGHHLN_00217 1.8e-49
HCIGHHLN_00218 1.7e-128 K Transcriptional regulatory protein, C terminal
HCIGHHLN_00219 6.8e-251 T PhoQ Sensor
HCIGHHLN_00220 3.3e-65 K helix_turn_helix, mercury resistance
HCIGHHLN_00221 9.7e-253 ydiC1 EGP Major facilitator Superfamily
HCIGHHLN_00222 1e-40
HCIGHHLN_00223 5.2e-42
HCIGHHLN_00224 5.5e-118
HCIGHHLN_00225 8.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
HCIGHHLN_00226 1.3e-120 K Bacterial regulatory proteins, tetR family
HCIGHHLN_00227 1.8e-72 K Transcriptional regulator
HCIGHHLN_00228 4.6e-70
HCIGHHLN_00229 1.1e-99 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HCIGHHLN_00230 9.2e-144
HCIGHHLN_00231 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HCIGHHLN_00232 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_00233 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HCIGHHLN_00234 3.5e-129 treR K UTRA
HCIGHHLN_00235 3.7e-42
HCIGHHLN_00236 7.3e-43 S Protein of unknown function (DUF2089)
HCIGHHLN_00237 4.3e-141 pnuC H nicotinamide mononucleotide transporter
HCIGHHLN_00238 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
HCIGHHLN_00239 2.2e-165 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HCIGHHLN_00240 3.7e-210 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HCIGHHLN_00241 1.6e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
HCIGHHLN_00242 4.5e-191 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HCIGHHLN_00243 4.6e-129 4.1.2.14 S KDGP aldolase
HCIGHHLN_00244 1.4e-201 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
HCIGHHLN_00245 2.3e-212 dho 3.5.2.3 S Amidohydrolase family
HCIGHHLN_00246 8.5e-212 S Bacterial protein of unknown function (DUF871)
HCIGHHLN_00247 4.7e-39
HCIGHHLN_00248 4.8e-233 pts3C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00249 2.3e-122 K helix_turn_helix gluconate operon transcriptional repressor
HCIGHHLN_00250 2.7e-97 yieF S NADPH-dependent FMN reductase
HCIGHHLN_00251 7.6e-255 S Uncharacterized protein conserved in bacteria (DUF2252)
HCIGHHLN_00252 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
HCIGHHLN_00253 2e-62
HCIGHHLN_00254 6.6e-96
HCIGHHLN_00255 1.1e-50
HCIGHHLN_00256 1.4e-56 trxA1 O Belongs to the thioredoxin family
HCIGHHLN_00257 2.1e-73
HCIGHHLN_00258 4.3e-222 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HCIGHHLN_00259 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00260 0.0 mtlR K Mga helix-turn-helix domain
HCIGHHLN_00261 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_00262 2.6e-277 pipD E Dipeptidase
HCIGHHLN_00263 4.8e-99 K Helix-turn-helix domain
HCIGHHLN_00264 3e-223 1.3.5.4 C FAD dependent oxidoreductase
HCIGHHLN_00265 4.5e-174 P Major Facilitator Superfamily
HCIGHHLN_00266 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HCIGHHLN_00267 4.7e-31 ygzD K Transcriptional
HCIGHHLN_00268 1e-69
HCIGHHLN_00269 4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCIGHHLN_00270 4.1e-158 dkgB S reductase
HCIGHHLN_00271 1.4e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HCIGHHLN_00272 9.2e-101 S ABC transporter permease
HCIGHHLN_00273 1.5e-258 P ABC transporter
HCIGHHLN_00274 8.9e-116 P cobalt transport
HCIGHHLN_00275 2.3e-260 S ATPases associated with a variety of cellular activities
HCIGHHLN_00276 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIGHHLN_00277 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCIGHHLN_00279 1e-218 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIGHHLN_00280 4e-164 FbpA K Domain of unknown function (DUF814)
HCIGHHLN_00281 1.3e-60 S Domain of unknown function (DU1801)
HCIGHHLN_00282 4.9e-34
HCIGHHLN_00283 1e-179 yghZ C Aldo keto reductase family protein
HCIGHHLN_00284 3e-113 pgm1 G phosphoglycerate mutase
HCIGHHLN_00285 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCIGHHLN_00286 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIGHHLN_00287 1.7e-78 yiaC K Acetyltransferase (GNAT) domain
HCIGHHLN_00288 3.5e-310 oppA E ABC transporter, substratebinding protein
HCIGHHLN_00289 0.0 oppA E ABC transporter, substratebinding protein
HCIGHHLN_00290 2.1e-157 hipB K Helix-turn-helix
HCIGHHLN_00292 0.0 3.6.4.13 M domain protein
HCIGHHLN_00293 7.7e-166 mleR K LysR substrate binding domain
HCIGHHLN_00294 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCIGHHLN_00295 1.1e-217 nhaC C Na H antiporter NhaC
HCIGHHLN_00296 1.3e-165 3.5.1.10 C nadph quinone reductase
HCIGHHLN_00297 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCIGHHLN_00298 9.1e-173 scrR K Transcriptional regulator, LacI family
HCIGHHLN_00299 1.4e-305 scrB 3.2.1.26 GH32 G invertase
HCIGHHLN_00300 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HCIGHHLN_00301 9.2e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCIGHHLN_00302 1.5e-45 ygbF S Sugar efflux transporter for intercellular exchange
HCIGHHLN_00303 0.0 3.2.1.96 G Glycosyl hydrolase family 85
HCIGHHLN_00304 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCIGHHLN_00305 4e-209 msmK P Belongs to the ABC transporter superfamily
HCIGHHLN_00306 2e-260 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
HCIGHHLN_00307 5.3e-150 malA S maltodextrose utilization protein MalA
HCIGHHLN_00308 1.4e-161 malD P ABC transporter permease
HCIGHHLN_00309 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
HCIGHHLN_00310 2.1e-230 mdxE G Bacterial extracellular solute-binding protein
HCIGHHLN_00311 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HCIGHHLN_00312 7.5e-180 yvdE K helix_turn _helix lactose operon repressor
HCIGHHLN_00313 1e-190 malR K Transcriptional regulator, LacI family
HCIGHHLN_00314 8.6e-133 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_00315 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
HCIGHHLN_00316 1.9e-101 dhaL 2.7.1.121 S Dak2
HCIGHHLN_00317 1.9e-186 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCIGHHLN_00318 2.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
HCIGHHLN_00319 1.1e-92 K Bacterial regulatory proteins, tetR family
HCIGHHLN_00321 8.6e-74 folT 2.7.13.3 T ECF transporter, substrate-specific component
HCIGHHLN_00322 5.8e-275 C Electron transfer flavoprotein FAD-binding domain
HCIGHHLN_00323 3.1e-116 K Transcriptional regulator
HCIGHHLN_00324 1e-298 M Exporter of polyketide antibiotics
HCIGHHLN_00325 5.7e-169 yjjC V ABC transporter
HCIGHHLN_00326 1.2e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HCIGHHLN_00327 9.1e-89
HCIGHHLN_00328 2.6e-149
HCIGHHLN_00329 1.9e-141
HCIGHHLN_00330 8.3e-54 K Transcriptional regulator PadR-like family
HCIGHHLN_00331 1.6e-129 K UbiC transcription regulator-associated domain protein
HCIGHHLN_00333 2.5e-98 S UPF0397 protein
HCIGHHLN_00334 0.0 ykoD P ABC transporter, ATP-binding protein
HCIGHHLN_00335 5.4e-150 cbiQ P cobalt transport
HCIGHHLN_00336 1.1e-175 C Oxidoreductase
HCIGHHLN_00337 7.5e-259
HCIGHHLN_00338 5e-52
HCIGHHLN_00339 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HCIGHHLN_00340 1.3e-81 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
HCIGHHLN_00341 1.2e-165 1.1.1.65 C Aldo keto reductase
HCIGHHLN_00342 1.5e-155 S reductase
HCIGHHLN_00344 8.1e-216 yeaN P Transporter, major facilitator family protein
HCIGHHLN_00345 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_00346 4.7e-227 mdtG EGP Major facilitator Superfamily
HCIGHHLN_00347 6.1e-67 K LytTr DNA-binding domain
HCIGHHLN_00348 8.7e-30 S Protein of unknown function (DUF3021)
HCIGHHLN_00349 1.7e-72 hsp1 O Belongs to the small heat shock protein (HSP20) family
HCIGHHLN_00350 1.2e-74 papX3 K Transcriptional regulator
HCIGHHLN_00351 7.2e-112 S NADPH-dependent FMN reductase
HCIGHHLN_00352 1.6e-28 KT PspC domain
HCIGHHLN_00353 0.0 pacL1 P P-type ATPase
HCIGHHLN_00354 1.1e-149 ydjP I Alpha/beta hydrolase family
HCIGHHLN_00355 2.1e-123
HCIGHHLN_00356 2.6e-250 yifK E Amino acid permease
HCIGHHLN_00357 9.9e-85 F NUDIX domain
HCIGHHLN_00358 1.8e-303 L HIRAN domain
HCIGHHLN_00359 1.5e-135 S peptidase C26
HCIGHHLN_00360 5.8e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
HCIGHHLN_00361 1.5e-110 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCIGHHLN_00362 2.6e-149 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HCIGHHLN_00363 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCIGHHLN_00364 4.2e-178 1.6.5.5 C Zinc-binding dehydrogenase
HCIGHHLN_00365 2.8e-151 larE S NAD synthase
HCIGHHLN_00366 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_00367 5e-75 larC 4.99.1.12 S Protein of unknown function DUF111
HCIGHHLN_00368 6.3e-132 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HCIGHHLN_00369 5.3e-122 larB S AIR carboxylase
HCIGHHLN_00370 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HCIGHHLN_00371 4.2e-121 K Crp-like helix-turn-helix domain
HCIGHHLN_00372 4.8e-182 nikMN P PDGLE domain
HCIGHHLN_00373 2.6e-149 P Cobalt transport protein
HCIGHHLN_00374 3.9e-128 cbiO P ABC transporter
HCIGHHLN_00375 4.8e-40
HCIGHHLN_00376 7e-110 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
HCIGHHLN_00378 1.2e-140
HCIGHHLN_00379 4.5e-280 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
HCIGHHLN_00380 6e-76
HCIGHHLN_00381 1e-139 S Belongs to the UPF0246 family
HCIGHHLN_00382 2.5e-166 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HCIGHHLN_00383 3.9e-235 mepA V MATE efflux family protein
HCIGHHLN_00384 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_00385 5.4e-181 1.1.1.1 C nadph quinone reductase
HCIGHHLN_00386 2e-126 hchA S DJ-1/PfpI family
HCIGHHLN_00387 3.6e-93 MA20_25245 K FR47-like protein
HCIGHHLN_00388 3.6e-152 EG EamA-like transporter family
HCIGHHLN_00389 2.7e-61 S Protein of unknown function
HCIGHHLN_00390 8.2e-39 S Protein of unknown function
HCIGHHLN_00391 0.0 tetP J elongation factor G
HCIGHHLN_00392 1e-116 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCIGHHLN_00393 5.5e-172 yobV1 K WYL domain
HCIGHHLN_00394 1.4e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HCIGHHLN_00395 2.9e-81 6.3.3.2 S ASCH
HCIGHHLN_00396 1.4e-254 1.14.14.9 Q 4-hydroxyphenylacetate
HCIGHHLN_00397 1.7e-134 wzb 3.1.3.48 T Tyrosine phosphatase family
HCIGHHLN_00398 7.4e-250 yjjP S Putative threonine/serine exporter
HCIGHHLN_00399 1.1e-194 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCIGHHLN_00400 5.5e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HCIGHHLN_00401 1.3e-290 QT PucR C-terminal helix-turn-helix domain
HCIGHHLN_00402 1.3e-122 drgA C Nitroreductase family
HCIGHHLN_00403 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
HCIGHHLN_00404 2.3e-164 ptlF S KR domain
HCIGHHLN_00405 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HCIGHHLN_00406 1e-72 C FMN binding
HCIGHHLN_00407 5.7e-158 K LysR family
HCIGHHLN_00408 1.6e-258 P Sodium:sulfate symporter transmembrane region
HCIGHHLN_00409 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
HCIGHHLN_00410 1.8e-116 S Elongation factor G-binding protein, N-terminal
HCIGHHLN_00411 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HCIGHHLN_00412 8.2e-122 pnb C nitroreductase
HCIGHHLN_00413 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HCIGHHLN_00414 2.2e-168 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HCIGHHLN_00415 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
HCIGHHLN_00416 1.5e-95 K Bacterial regulatory proteins, tetR family
HCIGHHLN_00417 3.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCIGHHLN_00418 6.8e-173 htrA 3.4.21.107 O serine protease
HCIGHHLN_00419 8.9e-158 vicX 3.1.26.11 S domain protein
HCIGHHLN_00420 2.2e-151 yycI S YycH protein
HCIGHHLN_00421 1.2e-244 yycH S YycH protein
HCIGHHLN_00422 0.0 vicK 2.7.13.3 T Histidine kinase
HCIGHHLN_00423 6.2e-131 K response regulator
HCIGHHLN_00425 1.7e-37
HCIGHHLN_00426 1.6e-31 cspA K Cold shock protein domain
HCIGHHLN_00427 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
HCIGHHLN_00428 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HCIGHHLN_00429 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HCIGHHLN_00430 1.7e-142 S haloacid dehalogenase-like hydrolase
HCIGHHLN_00432 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
HCIGHHLN_00433 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCIGHHLN_00434 1.8e-278 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
HCIGHHLN_00435 8.2e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
HCIGHHLN_00436 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCIGHHLN_00437 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCIGHHLN_00438 1.9e-276 E ABC transporter, substratebinding protein
HCIGHHLN_00440 1.9e-228 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCIGHHLN_00441 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCIGHHLN_00442 3.7e-224 yttB EGP Major facilitator Superfamily
HCIGHHLN_00443 1.1e-240 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCIGHHLN_00444 1.4e-67 rplI J Binds to the 23S rRNA
HCIGHHLN_00445 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HCIGHHLN_00446 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCIGHHLN_00447 6.8e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HCIGHHLN_00448 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HCIGHHLN_00449 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIGHHLN_00450 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCIGHHLN_00451 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCIGHHLN_00452 5e-37 yaaA S S4 domain protein YaaA
HCIGHHLN_00453 1e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCIGHHLN_00454 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCIGHHLN_00455 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HCIGHHLN_00456 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIGHHLN_00457 7.7e-310 E ABC transporter, substratebinding protein
HCIGHHLN_00458 9.3e-239 Q Imidazolonepropionase and related amidohydrolases
HCIGHHLN_00459 5e-123 jag S R3H domain protein
HCIGHHLN_00460 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HCIGHHLN_00461 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HCIGHHLN_00462 6.9e-93 S Cell surface protein
HCIGHHLN_00463 3.6e-159 S Bacterial protein of unknown function (DUF916)
HCIGHHLN_00465 1.1e-302
HCIGHHLN_00466 3.6e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCIGHHLN_00468 1.5e-255 pepC 3.4.22.40 E aminopeptidase
HCIGHHLN_00469 9.3e-58 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
HCIGHHLN_00470 3.6e-157 degV S DegV family
HCIGHHLN_00471 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
HCIGHHLN_00472 6.7e-142 tesE Q hydratase
HCIGHHLN_00473 7.9e-96 padC Q Phenolic acid decarboxylase
HCIGHHLN_00474 2.2e-99 padR K Virulence activator alpha C-term
HCIGHHLN_00475 2.7e-79 T Universal stress protein family
HCIGHHLN_00476 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCIGHHLN_00477 5.9e-188 rbsR K helix_turn _helix lactose operon repressor
HCIGHHLN_00478 2.3e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCIGHHLN_00479 1e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HCIGHHLN_00480 2.7e-160 rbsU U ribose uptake protein RbsU
HCIGHHLN_00481 3.8e-145 IQ NAD dependent epimerase/dehydratase family
HCIGHHLN_00482 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
HCIGHHLN_00483 1.1e-86 gutM K Glucitol operon activator protein (GutM)
HCIGHHLN_00484 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
HCIGHHLN_00485 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
HCIGHHLN_00486 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCIGHHLN_00487 6.8e-156 lrp QT PucR C-terminal helix-turn-helix domain
HCIGHHLN_00488 2.2e-193 rliB K helix_turn_helix gluconate operon transcriptional repressor
HCIGHHLN_00489 0.0 yknV V ABC transporter
HCIGHHLN_00490 0.0 mdlA2 V ABC transporter
HCIGHHLN_00491 6.5e-156 K AraC-like ligand binding domain
HCIGHHLN_00492 0.0 3.2.1.52 GH20 G Glycosyl hydrolase family 20, catalytic domain
HCIGHHLN_00493 5.2e-181 U Binding-protein-dependent transport system inner membrane component
HCIGHHLN_00494 1.5e-161 lplC U Binding-protein-dependent transport system inner membrane component
HCIGHHLN_00495 9.8e-280 G Domain of unknown function (DUF3502)
HCIGHHLN_00496 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HCIGHHLN_00497 4.1e-107 ypcB S integral membrane protein
HCIGHHLN_00498 0.0 yesM 2.7.13.3 T Histidine kinase
HCIGHHLN_00499 6.3e-271 yesN K helix_turn_helix, arabinose operon control protein
HCIGHHLN_00500 2.1e-165 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCIGHHLN_00501 9.1e-217 msmX P Belongs to the ABC transporter superfamily
HCIGHHLN_00502 0.0 ypdD G Glycosyl hydrolase family 92
HCIGHHLN_00503 1e-193 rliB K Transcriptional regulator
HCIGHHLN_00504 3.1e-253 S Metal-independent alpha-mannosidase (GH125)
HCIGHHLN_00505 0.0 mngB 2.3.1.204, 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HCIGHHLN_00506 2.1e-160 ypbG 2.7.1.2 GK ROK family
HCIGHHLN_00507 5.9e-287 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_00508 4.8e-20
HCIGHHLN_00509 5.4e-74 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HCIGHHLN_00510 3.6e-28 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HCIGHHLN_00511 2.6e-105 M Glycosyl hydrolases family 25
HCIGHHLN_00513 6.4e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HCIGHHLN_00514 2.1e-263 frdC 1.3.5.4 C FAD binding domain
HCIGHHLN_00515 1.2e-94 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HCIGHHLN_00516 1.2e-160 mleR K LysR family transcriptional regulator
HCIGHHLN_00517 5.2e-167 mleR K LysR family
HCIGHHLN_00518 1.6e-307 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HCIGHHLN_00519 1.4e-165 mleP S Sodium Bile acid symporter family
HCIGHHLN_00520 4.9e-244 yfnA E Amino Acid
HCIGHHLN_00521 3.9e-99 S ECF transporter, substrate-specific component
HCIGHHLN_00522 3.1e-23
HCIGHHLN_00523 9.4e-305 S Alpha beta
HCIGHHLN_00524 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
HCIGHHLN_00525 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HCIGHHLN_00526 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HCIGHHLN_00527 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HCIGHHLN_00528 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
HCIGHHLN_00529 2.3e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCIGHHLN_00530 2.9e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCIGHHLN_00531 3.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
HCIGHHLN_00532 2.6e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
HCIGHHLN_00533 2.7e-103 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCIGHHLN_00534 1e-93 S UPF0316 protein
HCIGHHLN_00535 1.1e-217 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCIGHHLN_00536 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HCIGHHLN_00537 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCIGHHLN_00538 2.6e-198 camS S sex pheromone
HCIGHHLN_00539 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIGHHLN_00540 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCIGHHLN_00541 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCIGHHLN_00542 1e-190 yegS 2.7.1.107 G Lipid kinase
HCIGHHLN_00543 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIGHHLN_00544 2.1e-100 yobS K Bacterial regulatory proteins, tetR family
HCIGHHLN_00545 0.0 yfgQ P E1-E2 ATPase
HCIGHHLN_00546 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00547 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_00548 2.3e-151 gntR K rpiR family
HCIGHHLN_00549 1.1e-144 lys M Glycosyl hydrolases family 25
HCIGHHLN_00550 1.1e-62 S Domain of unknown function (DUF4828)
HCIGHHLN_00551 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
HCIGHHLN_00552 8.4e-190 mocA S Oxidoreductase
HCIGHHLN_00553 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
HCIGHHLN_00555 2.3e-75 T Universal stress protein family
HCIGHHLN_00556 1.4e-245 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_00557 1.8e-164 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_00559 1.3e-73
HCIGHHLN_00560 5e-107
HCIGHHLN_00561 4.9e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCIGHHLN_00562 1.2e-219 pbpX1 V Beta-lactamase
HCIGHHLN_00563 6.8e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HCIGHHLN_00564 1.3e-157 yihY S Belongs to the UPF0761 family
HCIGHHLN_00565 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_00566 3.2e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
HCIGHHLN_00567 1.1e-50 gtcA S Teichoic acid glycosylation protein
HCIGHHLN_00568 2.6e-304
HCIGHHLN_00569 9.3e-113 cps3D
HCIGHHLN_00571 2.3e-168 cps3F
HCIGHHLN_00572 1.6e-136 rfbN GT2 S Glycosyltransferase like family 2
HCIGHHLN_00573 1.4e-78 S Glycosyl transferase family 2
HCIGHHLN_00574 6.5e-88 welB S Glycosyltransferase like family 2
HCIGHHLN_00575 2.2e-131 rgpB GT2 M Glycosyl transferase family 2
HCIGHHLN_00576 3.4e-147 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCIGHHLN_00577 1.4e-120 1.1.1.133 S Glycosyltransferase like family 2
HCIGHHLN_00578 2.1e-138 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
HCIGHHLN_00579 8.5e-160 rfbJ M Glycosyl transferase family 2
HCIGHHLN_00580 1e-225 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HCIGHHLN_00581 9.7e-106 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
HCIGHHLN_00582 8e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCIGHHLN_00583 2.3e-156 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCIGHHLN_00584 4.6e-103 L Integrase
HCIGHHLN_00585 3.9e-131 epsB M biosynthesis protein
HCIGHHLN_00586 1.3e-128 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HCIGHHLN_00587 3e-139 ywqE 3.1.3.48 GM PHP domain protein
HCIGHHLN_00588 4.6e-174 cps2D 5.1.3.2 M RmlD substrate binding domain
HCIGHHLN_00589 1.4e-124 tuaA M Bacterial sugar transferase
HCIGHHLN_00590 9.9e-47 wceM M Glycosyltransferase like family 2
HCIGHHLN_00591 5e-150 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HCIGHHLN_00593 2.7e-127 waaB GT4 M Glycosyl transferases group 1
HCIGHHLN_00594 3.5e-132 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
HCIGHHLN_00595 7.3e-241 cps2I S Psort location CytoplasmicMembrane, score
HCIGHHLN_00596 1.1e-92 S Acyltransferase family
HCIGHHLN_00597 9e-19 relB L bacterial-type proximal promoter sequence-specific DNA binding
HCIGHHLN_00598 6.5e-133 cps3A S Glycosyltransferase like family 2
HCIGHHLN_00599 2.8e-179 cps3B S Glycosyltransferase like family 2
HCIGHHLN_00600 1.1e-222 glf 5.4.99.9 M UDP-galactopyranose mutase
HCIGHHLN_00601 4.9e-204 cps3D
HCIGHHLN_00602 5.3e-110 cps3E
HCIGHHLN_00603 4.7e-155 cps3F
HCIGHHLN_00604 1.1e-203 cps3H
HCIGHHLN_00605 4.3e-200 cps3I G Acyltransferase family
HCIGHHLN_00606 1.4e-147 cps1D M Domain of unknown function (DUF4422)
HCIGHHLN_00607 6.7e-136 K helix_turn_helix, arabinose operon control protein
HCIGHHLN_00608 0.0 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HCIGHHLN_00609 9.6e-74 K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_00610 7e-259 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
HCIGHHLN_00611 3.2e-121 rfbP M Bacterial sugar transferase
HCIGHHLN_00612 1.1e-52
HCIGHHLN_00613 7.3e-33 S Protein of unknown function (DUF2922)
HCIGHHLN_00614 7e-30
HCIGHHLN_00615 1.3e-25
HCIGHHLN_00616 3e-101 K DNA-templated transcription, initiation
HCIGHHLN_00617 3.9e-125
HCIGHHLN_00618 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
HCIGHHLN_00619 4.1e-106 ygaC J Belongs to the UPF0374 family
HCIGHHLN_00620 2.5e-133 cwlO M NlpC/P60 family
HCIGHHLN_00621 7.8e-48 K sequence-specific DNA binding
HCIGHHLN_00622 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
HCIGHHLN_00623 2.5e-145 pbpX V Beta-lactamase
HCIGHHLN_00624 1.3e-168 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCIGHHLN_00625 9.3e-188 yueF S AI-2E family transporter
HCIGHHLN_00626 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HCIGHHLN_00627 2.1e-212 gntP EG Gluconate
HCIGHHLN_00628 1e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HCIGHHLN_00629 1.1e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HCIGHHLN_00630 3.1e-253 gor 1.8.1.7 C Glutathione reductase
HCIGHHLN_00631 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HCIGHHLN_00632 2.9e-273
HCIGHHLN_00633 5.5e-197 M MucBP domain
HCIGHHLN_00634 7.1e-161 lysR5 K LysR substrate binding domain
HCIGHHLN_00635 5.5e-126 yxaA S membrane transporter protein
HCIGHHLN_00636 3.2e-57 ywjH S Protein of unknown function (DUF1634)
HCIGHHLN_00637 1.3e-309 oppA E ABC transporter, substratebinding protein
HCIGHHLN_00638 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIGHHLN_00639 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HCIGHHLN_00640 9.2e-203 oppD P Belongs to the ABC transporter superfamily
HCIGHHLN_00641 1.8e-181 oppF P Belongs to the ABC transporter superfamily
HCIGHHLN_00642 1e-63 K Winged helix DNA-binding domain
HCIGHHLN_00643 1.6e-102 L Integrase
HCIGHHLN_00644 0.0 clpE O Belongs to the ClpA ClpB family
HCIGHHLN_00645 6.5e-30
HCIGHHLN_00646 2.7e-39 ptsH G phosphocarrier protein HPR
HCIGHHLN_00647 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HCIGHHLN_00648 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HCIGHHLN_00649 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
HCIGHHLN_00650 1.3e-188 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCIGHHLN_00651 4.3e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCIGHHLN_00652 6.5e-226 patA 2.6.1.1 E Aminotransferase
HCIGHHLN_00653 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
HCIGHHLN_00654 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCIGHHLN_00655 6.4e-156 G Peptidase_C39 like family
HCIGHHLN_00656 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HCIGHHLN_00657 3.4e-133 manY G PTS system
HCIGHHLN_00658 3.6e-171 manN G system, mannose fructose sorbose family IID component
HCIGHHLN_00659 4.7e-64 S Domain of unknown function (DUF956)
HCIGHHLN_00660 0.0 levR K Sigma-54 interaction domain
HCIGHHLN_00661 8.6e-72 pts10A 2.7.1.191 G PTS system fructose IIA component
HCIGHHLN_00662 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HCIGHHLN_00663 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCIGHHLN_00664 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
HCIGHHLN_00665 3.4e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
HCIGHHLN_00666 9.8e-141 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCIGHHLN_00667 1.8e-136 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
HCIGHHLN_00668 4.8e-168 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCIGHHLN_00669 3.3e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HCIGHHLN_00670 1.7e-177 EG EamA-like transporter family
HCIGHHLN_00671 2.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCIGHHLN_00672 3.9e-113 zmp2 O Zinc-dependent metalloprotease
HCIGHHLN_00673 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
HCIGHHLN_00674 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCIGHHLN_00675 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
HCIGHHLN_00676 2.1e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HCIGHHLN_00677 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCIGHHLN_00678 3.7e-205 yacL S domain protein
HCIGHHLN_00679 8.9e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCIGHHLN_00680 6.7e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCIGHHLN_00681 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HCIGHHLN_00682 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIGHHLN_00683 5.3e-98 yacP S YacP-like NYN domain
HCIGHHLN_00684 2.4e-101 sigH K Sigma-70 region 2
HCIGHHLN_00685 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCIGHHLN_00686 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCIGHHLN_00687 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
HCIGHHLN_00688 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_00689 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCIGHHLN_00690 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCIGHHLN_00691 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCIGHHLN_00692 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCIGHHLN_00693 9.3e-178 F DNA/RNA non-specific endonuclease
HCIGHHLN_00694 9.9e-38 L nuclease
HCIGHHLN_00695 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HCIGHHLN_00696 2.1e-108 yvdD 3.2.2.10 S Belongs to the LOG family
HCIGHHLN_00697 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIGHHLN_00698 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIGHHLN_00699 6.5e-37 nrdH O Glutaredoxin
HCIGHHLN_00700 5.7e-109 rsmC 2.1.1.172 J Methyltransferase
HCIGHHLN_00701 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCIGHHLN_00702 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIGHHLN_00703 5.8e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HCIGHHLN_00704 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCIGHHLN_00705 2.2e-38 yaaL S Protein of unknown function (DUF2508)
HCIGHHLN_00706 2.1e-240 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_00707 1.1e-50 2.7.1.194, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_00708 1.1e-40 ulaB_1 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_00709 2e-220 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HCIGHHLN_00710 2.5e-99 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HCIGHHLN_00711 8.7e-119 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCIGHHLN_00712 2.4e-53 yaaQ S Cyclic-di-AMP receptor
HCIGHHLN_00713 3.3e-186 holB 2.7.7.7 L DNA polymerase III
HCIGHHLN_00714 1e-57 yabA L Involved in initiation control of chromosome replication
HCIGHHLN_00715 5.4e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCIGHHLN_00716 2.1e-148 fat 3.1.2.21 I Acyl-ACP thioesterase
HCIGHHLN_00717 2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCIGHHLN_00718 5.5e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
HCIGHHLN_00719 5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
HCIGHHLN_00720 1.7e-143 phnE1 3.6.1.63 U ABC transporter permease
HCIGHHLN_00721 7.7e-138 phnE 3.6.1.63 U Phosphonate ABC transporter permease
HCIGHHLN_00722 9.7e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HCIGHHLN_00723 5.1e-190 phnD P Phosphonate ABC transporter
HCIGHHLN_00724 5e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HCIGHHLN_00725 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HCIGHHLN_00726 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HCIGHHLN_00727 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCIGHHLN_00728 4.1e-297 uup S ABC transporter, ATP-binding protein
HCIGHHLN_00729 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HCIGHHLN_00730 5.7e-83 GM NAD(P)H-binding
HCIGHHLN_00731 2.1e-140 EGP Major Facilitator Superfamily
HCIGHHLN_00732 5.2e-140 akr5f 1.1.1.346 S reductase
HCIGHHLN_00733 2.2e-130 C Aldo keto reductase
HCIGHHLN_00734 3.6e-113 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_00735 2.8e-20 adhR K helix_turn_helix, mercury resistance
HCIGHHLN_00736 1.8e-25 fldA C Flavodoxin
HCIGHHLN_00738 2e-78 K Transcriptional regulator
HCIGHHLN_00739 6.4e-109 akr5f 1.1.1.346 S reductase
HCIGHHLN_00740 2.5e-86 GM NAD(P)H-binding
HCIGHHLN_00741 8.1e-85 glcU U sugar transport
HCIGHHLN_00742 3e-126 IQ reductase
HCIGHHLN_00743 4.2e-76 darA C Flavodoxin
HCIGHHLN_00744 3.3e-82 yiiE S Protein of unknown function (DUF1211)
HCIGHHLN_00745 4.7e-141 aRA11 1.1.1.346 S reductase
HCIGHHLN_00746 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
HCIGHHLN_00747 5.2e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCIGHHLN_00748 1.2e-103 GM NAD(P)H-binding
HCIGHHLN_00749 2.8e-157 K LysR substrate binding domain
HCIGHHLN_00750 2.2e-63 S Domain of unknown function (DUF4440)
HCIGHHLN_00751 2.6e-112 pgm8 G Histidine phosphatase superfamily (branch 1)
HCIGHHLN_00752 8.2e-48
HCIGHHLN_00753 1.6e-36
HCIGHHLN_00754 1.9e-86 yvbK 3.1.3.25 K GNAT family
HCIGHHLN_00755 1.6e-82
HCIGHHLN_00756 4.3e-112 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCIGHHLN_00757 4.2e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCIGHHLN_00758 1.4e-99 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCIGHHLN_00759 8e-117 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCIGHHLN_00761 1.4e-119 macB V ABC transporter, ATP-binding protein
HCIGHHLN_00762 0.0 ylbB V ABC transporter permease
HCIGHHLN_00763 1.7e-235 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCIGHHLN_00764 4.4e-79 K transcriptional regulator, MerR family
HCIGHHLN_00765 3.2e-76 yphH S Cupin domain
HCIGHHLN_00766 2.5e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCIGHHLN_00767 1e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_00768 1.8e-210 natB CP ABC-2 family transporter protein
HCIGHHLN_00769 3.6e-168 natA S ABC transporter, ATP-binding protein
HCIGHHLN_00770 1.8e-92 ogt 2.1.1.63 L Methyltransferase
HCIGHHLN_00771 8.6e-52 lytE M LysM domain
HCIGHHLN_00773 2e-267 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIGHHLN_00774 5.8e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
HCIGHHLN_00775 3.7e-151 rlrG K Transcriptional regulator
HCIGHHLN_00776 9.3e-173 S Conserved hypothetical protein 698
HCIGHHLN_00777 1.8e-101 rimL J Acetyltransferase (GNAT) domain
HCIGHHLN_00778 1.3e-74 S Domain of unknown function (DUF4811)
HCIGHHLN_00779 3.2e-270 lmrB EGP Major facilitator Superfamily
HCIGHHLN_00780 3.1e-124 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCIGHHLN_00781 7.6e-190 ynfM EGP Major facilitator Superfamily
HCIGHHLN_00782 1.3e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
HCIGHHLN_00783 1.2e-155 mleP3 S Membrane transport protein
HCIGHHLN_00784 7.5e-110 S Membrane
HCIGHHLN_00785 1.5e-187 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HCIGHHLN_00786 1.1e-98 1.5.1.3 H RibD C-terminal domain
HCIGHHLN_00787 2.1e-185 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCIGHHLN_00788 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
HCIGHHLN_00789 5.6e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HCIGHHLN_00790 5.2e-174 hrtB V ABC transporter permease
HCIGHHLN_00791 6.6e-95 S Protein of unknown function (DUF1440)
HCIGHHLN_00792 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HCIGHHLN_00794 3e-252 dtpT U amino acid peptide transporter
HCIGHHLN_00795 2e-151 yjjH S Calcineurin-like phosphoesterase
HCIGHHLN_00799 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
HCIGHHLN_00800 3.2e-53 S Cupin domain
HCIGHHLN_00801 2.7e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HCIGHHLN_00802 4.7e-194 ybiR P Citrate transporter
HCIGHHLN_00803 1.6e-151 pnuC H nicotinamide mononucleotide transporter
HCIGHHLN_00804 1.7e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCIGHHLN_00805 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HCIGHHLN_00806 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
HCIGHHLN_00807 1.2e-137 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HCIGHHLN_00808 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCIGHHLN_00809 4.7e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HCIGHHLN_00810 0.0 pacL 3.6.3.8 P P-type ATPase
HCIGHHLN_00811 3.4e-71
HCIGHHLN_00812 0.0 yhgF K Tex-like protein N-terminal domain protein
HCIGHHLN_00813 1.8e-80 ydcK S Belongs to the SprT family
HCIGHHLN_00814 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HCIGHHLN_00815 3.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCIGHHLN_00817 5.9e-54 sip L Belongs to the 'phage' integrase family
HCIGHHLN_00818 1.8e-112 S Protein of unknown function (DUF3644)
HCIGHHLN_00820 1.2e-13
HCIGHHLN_00821 4.8e-17 E Pfam:DUF955
HCIGHHLN_00822 3.9e-23 yvaO K Helix-turn-helix XRE-family like proteins
HCIGHHLN_00824 4.8e-29 S Hypothetical protein (DUF2513)
HCIGHHLN_00825 2.5e-19
HCIGHHLN_00826 2.8e-07
HCIGHHLN_00829 3.6e-17
HCIGHHLN_00834 5.3e-41 S Siphovirus Gp157
HCIGHHLN_00836 4.3e-159 S helicase activity
HCIGHHLN_00837 1.3e-72 L AAA domain
HCIGHHLN_00838 4.3e-27
HCIGHHLN_00839 2.3e-78 S Bifunctional DNA primase/polymerase, N-terminal
HCIGHHLN_00840 2.6e-132 S Virulence-associated protein E
HCIGHHLN_00841 1.9e-37 S hydrolase activity, acting on ester bonds
HCIGHHLN_00842 9.6e-16
HCIGHHLN_00845 4.6e-55 S YopX protein
HCIGHHLN_00847 3.6e-17 S Domain of unknown function (DUF4145)
HCIGHHLN_00848 4e-29
HCIGHHLN_00850 1.3e-25 V HNH nucleases
HCIGHHLN_00853 6.2e-13
HCIGHHLN_00854 9.7e-175 S Terminase
HCIGHHLN_00855 6.7e-103 S Phage portal protein
HCIGHHLN_00856 2.4e-56 clpP 3.4.21.92 OU Clp protease
HCIGHHLN_00857 1.1e-113 S Phage capsid family
HCIGHHLN_00858 9.8e-17
HCIGHHLN_00859 4.7e-24
HCIGHHLN_00860 5.9e-33
HCIGHHLN_00861 1.4e-21
HCIGHHLN_00862 6.9e-38 S Phage tail tube protein
HCIGHHLN_00864 1e-138 M Phage tail tape measure protein TP901
HCIGHHLN_00865 3.1e-33 S Phage tail protein
HCIGHHLN_00866 4.1e-123 sidC GT2,GT4 LM DNA recombination
HCIGHHLN_00868 9.7e-17
HCIGHHLN_00869 4.5e-63 J tRNA cytidylyltransferase activity
HCIGHHLN_00870 6.3e-97 L Resolvase, N terminal domain
HCIGHHLN_00871 3.5e-12 L Helix-turn-helix domain
HCIGHHLN_00872 6.7e-45 L Transposase and inactivated derivatives, IS30 family
HCIGHHLN_00873 3.8e-08
HCIGHHLN_00874 1.3e-64 yrkL S Flavodoxin-like fold
HCIGHHLN_00875 1.2e-50 L Resolvase, N terminal domain
HCIGHHLN_00877 6.6e-25 S Protein of unknown function C-terminal (DUF3324)
HCIGHHLN_00879 2e-91 G Glycosyl hydrolases family 8
HCIGHHLN_00880 5.4e-181 ydaM M Glycosyl transferase family group 2
HCIGHHLN_00881 2.7e-40
HCIGHHLN_00882 3.1e-54 L recombinase activity
HCIGHHLN_00883 0.0 kup P Transport of potassium into the cell
HCIGHHLN_00884 1.1e-63 KT transcriptional regulatory protein
HCIGHHLN_00885 7.2e-180 T PhoQ Sensor
HCIGHHLN_00886 7.5e-37 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HCIGHHLN_00887 2.4e-255 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HCIGHHLN_00888 6e-175 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HCIGHHLN_00891 3.9e-224 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HCIGHHLN_00892 4.7e-46
HCIGHHLN_00893 1.4e-54
HCIGHHLN_00894 1.1e-168 EGP Major facilitator Superfamily
HCIGHHLN_00895 5.1e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCIGHHLN_00896 6.9e-156 3.3.1.1 H adenosylhomocysteinase activity
HCIGHHLN_00897 3.3e-95 K Helix-turn-helix domain
HCIGHHLN_00898 6e-161 nsr 3.4.21.102 M Peptidase family S41
HCIGHHLN_00899 3.1e-148 L Psort location Cytoplasmic, score
HCIGHHLN_00900 9.3e-30
HCIGHHLN_00901 9.5e-254 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCIGHHLN_00902 0.0 traA L MobA MobL family protein
HCIGHHLN_00903 8.5e-163 dcm 2.1.1.37 H C-5 cytosine-specific DNA methylase
HCIGHHLN_00904 2.6e-115 mutH L DNA mismatch repair enzyme MutH
HCIGHHLN_00905 1.8e-70 tnpR L Resolvase, N terminal domain
HCIGHHLN_00906 2.1e-42 tnpR L Resolvase, N terminal domain
HCIGHHLN_00907 3e-181 1.17.4.1 F Ribonucleotide reductase, small chain
HCIGHHLN_00908 2.1e-171 nrdF 1.17.4.1 F Ribonucleotide reductase, small chain
HCIGHHLN_00909 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCIGHHLN_00910 6.2e-81 nrdI F NrdI Flavodoxin like
HCIGHHLN_00912 7e-20
HCIGHHLN_00914 6.7e-51 S Family of unknown function (DUF5388)
HCIGHHLN_00915 5.4e-147 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HCIGHHLN_00916 7.6e-70 L Transposase and inactivated derivatives, IS30 family
HCIGHHLN_00917 1.1e-75 dptF L COG0433 Predicted ATPase
HCIGHHLN_00918 1.7e-60 dptG
HCIGHHLN_00919 8.4e-257 S Domain of unknown function DUF87
HCIGHHLN_00920 5.1e-114 repA S Replication initiator protein A
HCIGHHLN_00921 7.4e-43 relB L Addiction module antitoxin, RelB DinJ family
HCIGHHLN_00922 2.3e-27
HCIGHHLN_00923 4.8e-89 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCIGHHLN_00924 3.2e-190 G phosphotransferase system
HCIGHHLN_00925 7.2e-154 G Protein of unknown function (DUF4038)
HCIGHHLN_00926 1e-94 purR13 K Bacterial regulatory proteins, lacI family
HCIGHHLN_00927 1.3e-239 G isomerase
HCIGHHLN_00928 5.8e-112 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
HCIGHHLN_00929 2.5e-103 tktA 2.2.1.1 G Transketolase, pyrimidine binding domain
HCIGHHLN_00930 2.3e-151 glpK_1 2.7.1.30 G FGGY family of carbohydrate kinases, C-terminal domain
HCIGHHLN_00931 5.4e-275 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_00933 1.6e-39 soj D PFAM Cobyrinic acid a,c-diamide synthase
HCIGHHLN_00934 7.2e-100 K Primase C terminal 1 (PriCT-1)
HCIGHHLN_00935 9.8e-34 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HCIGHHLN_00936 2.7e-48 tnp2PF3 L Transposase
HCIGHHLN_00937 2.1e-148 S Protein of unknown function DUF262
HCIGHHLN_00939 7.8e-70 tnp2PF3 L manually curated
HCIGHHLN_00940 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
HCIGHHLN_00941 4.8e-85
HCIGHHLN_00942 8.4e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HCIGHHLN_00943 8.9e-53
HCIGHHLN_00944 3e-63
HCIGHHLN_00945 2.8e-171 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIGHHLN_00946 1.5e-192 L Psort location Cytoplasmic, score
HCIGHHLN_00947 2.2e-18
HCIGHHLN_00948 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HCIGHHLN_00949 4.1e-76
HCIGHHLN_00951 3.5e-224 traK U TraM recognition site of TraD and TraG
HCIGHHLN_00952 5.3e-67
HCIGHHLN_00953 5.7e-43 CO COG0526, thiol-disulfide isomerase and thioredoxins
HCIGHHLN_00954 8.2e-55
HCIGHHLN_00955 1.9e-161 M CHAP domain
HCIGHHLN_00956 3.4e-221 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
HCIGHHLN_00957 0.0 traE U type IV secretory pathway VirB4
HCIGHHLN_00958 6.2e-117
HCIGHHLN_00959 7.8e-37
HCIGHHLN_00960 7.4e-50 S Cag pathogenicity island, type IV secretory system
HCIGHHLN_00961 1.2e-82
HCIGHHLN_00962 2.6e-14
HCIGHHLN_00963 0.0 L MobA MobL family protein
HCIGHHLN_00964 8e-18 L Transposase
HCIGHHLN_00965 2.4e-22 L Transposase
HCIGHHLN_00966 6.9e-40 L Transposase
HCIGHHLN_00967 1.7e-51 K helix_turn_helix, arabinose operon control protein
HCIGHHLN_00969 2e-07 D Mycoplasma protein of unknown function, DUF285
HCIGHHLN_00970 4.3e-09 3.4.21.72 M Bacterial Ig-like domain (group 3)
HCIGHHLN_00971 5e-16 K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_00972 1.8e-12 L Helix-turn-helix domain
HCIGHHLN_00973 2.1e-08 L Helix-turn-helix domain
HCIGHHLN_00976 6.9e-35 S Cell surface protein
HCIGHHLN_00977 2.5e-152
HCIGHHLN_00978 6.4e-13 K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_00979 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HCIGHHLN_00980 1e-200 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCIGHHLN_00981 4.4e-136 mutS L ATPase domain of DNA mismatch repair MUTS family
HCIGHHLN_00982 5.6e-124 mutS L ATPase domain of DNA mismatch repair MUTS family
HCIGHHLN_00983 1e-268 mutS L MutS domain V
HCIGHHLN_00984 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
HCIGHHLN_00985 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCIGHHLN_00986 4.9e-19 S NUDIX domain
HCIGHHLN_00987 0.0 S membrane
HCIGHHLN_00988 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HCIGHHLN_00989 1.8e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HCIGHHLN_00990 4.8e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HCIGHHLN_00991 4.7e-82 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HCIGHHLN_00992 9.3e-106 GBS0088 S Nucleotidyltransferase
HCIGHHLN_00993 1.4e-106
HCIGHHLN_00994 5.1e-116 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HCIGHHLN_00995 3.3e-112 K Bacterial regulatory proteins, tetR family
HCIGHHLN_00996 9.4e-242 npr 1.11.1.1 C NADH oxidase
HCIGHHLN_00997 0.0
HCIGHHLN_00998 7.9e-61
HCIGHHLN_00999 1.4e-192 S Fn3-like domain
HCIGHHLN_01000 4e-103 S WxL domain surface cell wall-binding
HCIGHHLN_01001 3.5e-78 S WxL domain surface cell wall-binding
HCIGHHLN_01002 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCIGHHLN_01003 2e-42
HCIGHHLN_01004 9.9e-82 hit FG histidine triad
HCIGHHLN_01005 1.6e-134 ecsA V ABC transporter, ATP-binding protein
HCIGHHLN_01006 1.2e-222 ecsB U ABC transporter
HCIGHHLN_01007 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HCIGHHLN_01008 9e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCIGHHLN_01009 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
HCIGHHLN_01010 2e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIGHHLN_01011 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HCIGHHLN_01012 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HCIGHHLN_01013 2.3e-20 S Virus attachment protein p12 family
HCIGHHLN_01014 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HCIGHHLN_01015 1.3e-34 feoA P FeoA domain
HCIGHHLN_01016 4.2e-144 sufC O FeS assembly ATPase SufC
HCIGHHLN_01017 2.6e-244 sufD O FeS assembly protein SufD
HCIGHHLN_01018 1.2e-233 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCIGHHLN_01019 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
HCIGHHLN_01020 1.4e-272 sufB O assembly protein SufB
HCIGHHLN_01021 5.5e-45 yitW S Iron-sulfur cluster assembly protein
HCIGHHLN_01022 3.1e-111 hipB K Helix-turn-helix
HCIGHHLN_01023 4.5e-121 ybhL S Belongs to the BI1 family
HCIGHHLN_01024 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCIGHHLN_01025 8.5e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HCIGHHLN_01026 2.7e-103 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCIGHHLN_01027 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCIGHHLN_01028 1.1e-248 dnaB L replication initiation and membrane attachment
HCIGHHLN_01029 3.3e-172 dnaI L Primosomal protein DnaI
HCIGHHLN_01030 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCIGHHLN_01031 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCIGHHLN_01032 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HCIGHHLN_01033 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCIGHHLN_01034 2.4e-55
HCIGHHLN_01035 6.5e-240 yrvN L AAA C-terminal domain
HCIGHHLN_01036 3.8e-198 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCIGHHLN_01037 1e-62 hxlR K Transcriptional regulator, HxlR family
HCIGHHLN_01038 7.5e-135 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
HCIGHHLN_01039 3.8e-251 pgaC GT2 M Glycosyl transferase
HCIGHHLN_01040 1.3e-79
HCIGHHLN_01041 1.4e-98 yqeG S HAD phosphatase, family IIIA
HCIGHHLN_01042 8.5e-215 yqeH S Ribosome biogenesis GTPase YqeH
HCIGHHLN_01043 1.1e-50 yhbY J RNA-binding protein
HCIGHHLN_01044 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCIGHHLN_01045 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HCIGHHLN_01046 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCIGHHLN_01047 5.8e-140 yqeM Q Methyltransferase
HCIGHHLN_01048 9.8e-219 ylbM S Belongs to the UPF0348 family
HCIGHHLN_01049 1.6e-97 yceD S Uncharacterized ACR, COG1399
HCIGHHLN_01050 2.2e-89 S Peptidase propeptide and YPEB domain
HCIGHHLN_01051 2.9e-171 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIGHHLN_01052 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCIGHHLN_01053 4.2e-245 rarA L recombination factor protein RarA
HCIGHHLN_01054 4.3e-121 K response regulator
HCIGHHLN_01055 1.2e-305 arlS 2.7.13.3 T Histidine kinase
HCIGHHLN_01056 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HCIGHHLN_01057 0.0 sbcC L Putative exonuclease SbcCD, C subunit
HCIGHHLN_01058 1.3e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HCIGHHLN_01059 1.9e-93 S SdpI/YhfL protein family
HCIGHHLN_01060 1e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HCIGHHLN_01061 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HCIGHHLN_01062 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCIGHHLN_01063 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCIGHHLN_01064 7.4e-64 yodB K Transcriptional regulator, HxlR family
HCIGHHLN_01065 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCIGHHLN_01066 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HCIGHHLN_01067 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCIGHHLN_01068 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
HCIGHHLN_01069 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCIGHHLN_01070 2.3e-96 liaI S membrane
HCIGHHLN_01071 4e-75 XK27_02470 K LytTr DNA-binding domain
HCIGHHLN_01072 1.5e-54 yneR S Belongs to the HesB IscA family
HCIGHHLN_01073 0.0 S membrane
HCIGHHLN_01074 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HCIGHHLN_01075 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HCIGHHLN_01076 2.8e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HCIGHHLN_01077 1e-114 gluP 3.4.21.105 S Peptidase, S54 family
HCIGHHLN_01078 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
HCIGHHLN_01079 5.7e-180 glk 2.7.1.2 G Glucokinase
HCIGHHLN_01080 2.2e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
HCIGHHLN_01081 4.4e-68 yqhL P Rhodanese-like protein
HCIGHHLN_01082 2e-22 WQ51_02665 S Protein of unknown function (DUF3042)
HCIGHHLN_01083 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
HCIGHHLN_01084 2.4e-175 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCIGHHLN_01085 4.6e-64 glnR K Transcriptional regulator
HCIGHHLN_01086 6.2e-265 glnA 6.3.1.2 E glutamine synthetase
HCIGHHLN_01087 2.5e-161
HCIGHHLN_01088 8.8e-181
HCIGHHLN_01089 6.2e-99 dut S Protein conserved in bacteria
HCIGHHLN_01090 1.8e-56
HCIGHHLN_01091 1.7e-30
HCIGHHLN_01094 5.4e-19
HCIGHHLN_01095 1.8e-89 K Transcriptional regulator
HCIGHHLN_01096 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCIGHHLN_01097 3.2e-53 ysxB J Cysteine protease Prp
HCIGHHLN_01098 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HCIGHHLN_01099 1.6e-194 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCIGHHLN_01100 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCIGHHLN_01101 3.5e-74 yqhY S Asp23 family, cell envelope-related function
HCIGHHLN_01102 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCIGHHLN_01103 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCIGHHLN_01104 9.3e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIGHHLN_01105 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCIGHHLN_01106 8.3e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCIGHHLN_01107 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HCIGHHLN_01108 7.4e-77 argR K Regulates arginine biosynthesis genes
HCIGHHLN_01109 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
HCIGHHLN_01110 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
HCIGHHLN_01111 1.2e-104 opuCB E ABC transporter permease
HCIGHHLN_01112 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HCIGHHLN_01113 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
HCIGHHLN_01114 1.7e-54
HCIGHHLN_01115 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HCIGHHLN_01116 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCIGHHLN_01117 4e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HCIGHHLN_01118 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCIGHHLN_01119 1.9e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCIGHHLN_01120 7.1e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HCIGHHLN_01121 1.7e-134 stp 3.1.3.16 T phosphatase
HCIGHHLN_01122 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HCIGHHLN_01123 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCIGHHLN_01124 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HCIGHHLN_01125 1.3e-122 thiN 2.7.6.2 H thiamine pyrophosphokinase
HCIGHHLN_01126 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HCIGHHLN_01127 1.8e-57 asp S Asp23 family, cell envelope-related function
HCIGHHLN_01128 0.0 yloV S DAK2 domain fusion protein YloV
HCIGHHLN_01129 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HCIGHHLN_01130 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HCIGHHLN_01131 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCIGHHLN_01132 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCIGHHLN_01133 0.0 smc D Required for chromosome condensation and partitioning
HCIGHHLN_01134 5.6e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCIGHHLN_01135 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HCIGHHLN_01136 2.9e-220 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCIGHHLN_01137 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCIGHHLN_01138 2.6e-39 ylqC S Belongs to the UPF0109 family
HCIGHHLN_01139 8.2e-96 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCIGHHLN_01140 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCIGHHLN_01141 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCIGHHLN_01142 1.7e-51
HCIGHHLN_01143 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HCIGHHLN_01144 2.4e-166 pelX UW LPXTG-motif cell wall anchor domain protein
HCIGHHLN_01145 1.4e-86
HCIGHHLN_01146 8.7e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HCIGHHLN_01147 2.8e-272 XK27_00765
HCIGHHLN_01149 6.8e-270 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
HCIGHHLN_01150 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
HCIGHHLN_01151 3.2e-165 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCIGHHLN_01152 2.4e-123 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HCIGHHLN_01153 2.2e-108 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HCIGHHLN_01154 4.3e-225 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCIGHHLN_01155 1.5e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCIGHHLN_01156 2e-97 entB 3.5.1.19 Q Isochorismatase family
HCIGHHLN_01157 1e-176 1.6.5.5 C Zinc-binding dehydrogenase
HCIGHHLN_01158 4.5e-67 ybbJ K Acetyltransferase (GNAT) family
HCIGHHLN_01159 9.9e-217 E glutamate:sodium symporter activity
HCIGHHLN_01160 6.5e-215 3.5.1.47 E Peptidase family M20/M25/M40
HCIGHHLN_01161 1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HCIGHHLN_01162 8.5e-60 S Protein of unknown function (DUF1648)
HCIGHHLN_01163 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_01164 3.8e-179 yneE K Transcriptional regulator
HCIGHHLN_01165 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HCIGHHLN_01166 1.7e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HCIGHHLN_01167 1.3e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HCIGHHLN_01168 2.9e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HCIGHHLN_01169 1.2e-126 IQ reductase
HCIGHHLN_01170 1.6e-227 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HCIGHHLN_01171 1.7e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HCIGHHLN_01172 1e-69 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HCIGHHLN_01173 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HCIGHHLN_01174 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HCIGHHLN_01175 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HCIGHHLN_01176 9.9e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HCIGHHLN_01177 4.9e-99 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HCIGHHLN_01178 1.7e-123 S Protein of unknown function (DUF554)
HCIGHHLN_01179 9.4e-161 K LysR substrate binding domain
HCIGHHLN_01180 4.6e-88 ykhA 3.1.2.20 I Thioesterase superfamily
HCIGHHLN_01181 1.7e-193 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HCIGHHLN_01182 3.1e-93 K transcriptional regulator
HCIGHHLN_01183 3.3e-303 norB EGP Major Facilitator
HCIGHHLN_01184 1.2e-139 f42a O Band 7 protein
HCIGHHLN_01185 5e-87 S Protein of unknown function with HXXEE motif
HCIGHHLN_01186 8.4e-14 K Bacterial regulatory proteins, tetR family
HCIGHHLN_01187 8.5e-54
HCIGHHLN_01188 1.3e-28
HCIGHHLN_01189 2.1e-208 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCIGHHLN_01190 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
HCIGHHLN_01191 5.8e-48 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
HCIGHHLN_01192 7.9e-41
HCIGHHLN_01193 1.9e-67 tspO T TspO/MBR family
HCIGHHLN_01194 6.3e-76 uspA T Belongs to the universal stress protein A family
HCIGHHLN_01195 8e-66 S Protein of unknown function (DUF805)
HCIGHHLN_01196 4.1e-164 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HCIGHHLN_01197 3.5e-36
HCIGHHLN_01198 3.1e-14
HCIGHHLN_01199 6.5e-41 S transglycosylase associated protein
HCIGHHLN_01200 4.8e-29 S CsbD-like
HCIGHHLN_01201 9.4e-40
HCIGHHLN_01202 7.3e-280 pipD E Dipeptidase
HCIGHHLN_01203 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HCIGHHLN_01204 5.7e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCIGHHLN_01205 1e-170 2.5.1.74 H UbiA prenyltransferase family
HCIGHHLN_01206 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
HCIGHHLN_01207 1.9e-49
HCIGHHLN_01208 2.4e-43
HCIGHHLN_01209 5.1e-259 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HCIGHHLN_01210 1.4e-265 yfnA E Amino Acid
HCIGHHLN_01211 1.2e-149 yitU 3.1.3.104 S hydrolase
HCIGHHLN_01212 1.4e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HCIGHHLN_01213 2.9e-90 S Domain of unknown function (DUF4767)
HCIGHHLN_01214 2.5e-250 malT G Major Facilitator
HCIGHHLN_01215 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HCIGHHLN_01216 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCIGHHLN_01217 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HCIGHHLN_01218 7.6e-205 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HCIGHHLN_01219 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HCIGHHLN_01220 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HCIGHHLN_01221 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HCIGHHLN_01222 2.1e-72 ypmB S protein conserved in bacteria
HCIGHHLN_01223 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HCIGHHLN_01224 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCIGHHLN_01225 1.3e-128 dnaD L Replication initiation and membrane attachment
HCIGHHLN_01227 2.7e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCIGHHLN_01228 7.7e-99 metI P ABC transporter permease
HCIGHHLN_01229 2.7e-157 metQ_4 P Belongs to the nlpA lipoprotein family
HCIGHHLN_01230 7.6e-83 uspA T Universal stress protein family
HCIGHHLN_01231 5.4e-303 ftpA P Binding-protein-dependent transport system inner membrane component
HCIGHHLN_01232 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
HCIGHHLN_01233 7.4e-180 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
HCIGHHLN_01234 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HCIGHHLN_01235 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HCIGHHLN_01236 8.3e-110 ypsA S Belongs to the UPF0398 family
HCIGHHLN_01237 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HCIGHHLN_01239 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HCIGHHLN_01240 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_01241 6.8e-243 P Major Facilitator Superfamily
HCIGHHLN_01242 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HCIGHHLN_01243 1.2e-73 S SnoaL-like domain
HCIGHHLN_01244 4.3e-154 M Glycosyltransferase, group 2 family protein
HCIGHHLN_01245 4e-40 M Glycosyltransferase, group 2 family protein
HCIGHHLN_01246 5.1e-209 mccF V LD-carboxypeptidase
HCIGHHLN_01247 1.6e-77 K Acetyltransferase (GNAT) domain
HCIGHHLN_01248 6.9e-240 M hydrolase, family 25
HCIGHHLN_01249 1.4e-181 mccF 3.4.17.13 V LD-carboxypeptidase
HCIGHHLN_01250 5e-73 XK27_05710 K Acetyltransferase (GNAT) domain
HCIGHHLN_01251 7.3e-122
HCIGHHLN_01252 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
HCIGHHLN_01253 1.1e-192
HCIGHHLN_01254 2.9e-145 S hydrolase activity, acting on ester bonds
HCIGHHLN_01255 3.2e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
HCIGHHLN_01256 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
HCIGHHLN_01257 7.4e-62 esbA S Family of unknown function (DUF5322)
HCIGHHLN_01258 1.7e-293 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HCIGHHLN_01259 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCIGHHLN_01260 1e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCIGHHLN_01261 1.3e-88 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCIGHHLN_01262 1.8e-206 carA 6.3.5.5 F Belongs to the CarA family
HCIGHHLN_01263 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCIGHHLN_01264 4e-288 S Bacterial membrane protein, YfhO
HCIGHHLN_01265 6.4e-113 pgm5 G Phosphoglycerate mutase family
HCIGHHLN_01266 5.8e-70 frataxin S Domain of unknown function (DU1801)
HCIGHHLN_01268 1.1e-129 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HCIGHHLN_01269 1.3e-68 S LuxR family transcriptional regulator
HCIGHHLN_01270 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
HCIGHHLN_01271 9.7e-91 3.6.1.55 F NUDIX domain
HCIGHHLN_01272 2.7e-163 V ABC transporter, ATP-binding protein
HCIGHHLN_01273 3.5e-132 S ABC-2 family transporter protein
HCIGHHLN_01274 0.0 FbpA K Fibronectin-binding protein
HCIGHHLN_01275 1.9e-66 K Transcriptional regulator
HCIGHHLN_01276 7e-161 degV S EDD domain protein, DegV family
HCIGHHLN_01277 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
HCIGHHLN_01278 3.4e-132 S Protein of unknown function (DUF975)
HCIGHHLN_01279 1.7e-09
HCIGHHLN_01280 1.6e-48
HCIGHHLN_01281 1.4e-147 2.7.7.12 C Domain of unknown function (DUF4931)
HCIGHHLN_01282 2.5e-209 pmrB EGP Major facilitator Superfamily
HCIGHHLN_01283 4.6e-12
HCIGHHLN_01284 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HCIGHHLN_01285 5.2e-129 yejC S Protein of unknown function (DUF1003)
HCIGHHLN_01286 2.5e-134 XK27_00890 S Domain of unknown function (DUF368)
HCIGHHLN_01287 2.1e-244 cycA E Amino acid permease
HCIGHHLN_01288 1e-114
HCIGHHLN_01289 4.1e-59
HCIGHHLN_01290 5.2e-279 lldP C L-lactate permease
HCIGHHLN_01291 5.1e-227
HCIGHHLN_01292 3.7e-128 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
HCIGHHLN_01293 4.1e-192 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
HCIGHHLN_01294 3.9e-196 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIGHHLN_01295 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIGHHLN_01296 8.5e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HCIGHHLN_01297 1.8e-72 mgrA K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_01298 3.2e-64 gshR1 1.8.1.7 C Glutathione reductase
HCIGHHLN_01299 8.6e-154 gshR1 1.8.1.7 C Glutathione reductase
HCIGHHLN_01300 2.1e-51
HCIGHHLN_01301 5.3e-245 M Glycosyl transferase family group 2
HCIGHHLN_01302 1e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCIGHHLN_01303 4.6e-157 xerD L Phage integrase, N-terminal SAM-like domain
HCIGHHLN_01304 4.2e-32 S YozE SAM-like fold
HCIGHHLN_01305 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIGHHLN_01306 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HCIGHHLN_01307 1.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HCIGHHLN_01308 1.2e-177 K Transcriptional regulator
HCIGHHLN_01309 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIGHHLN_01310 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HCIGHHLN_01311 6.7e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HCIGHHLN_01312 2.2e-170 lacX 5.1.3.3 G Aldose 1-epimerase
HCIGHHLN_01313 2.3e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HCIGHHLN_01314 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HCIGHHLN_01315 3.4e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HCIGHHLN_01316 2.5e-250 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HCIGHHLN_01317 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCIGHHLN_01318 3.3e-158 dprA LU DNA protecting protein DprA
HCIGHHLN_01319 9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIGHHLN_01320 1.8e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HCIGHHLN_01321 8.8e-228 XK27_05470 E Methionine synthase
HCIGHHLN_01322 9.6e-172 cpsY K Transcriptional regulator, LysR family
HCIGHHLN_01323 1.3e-20 EGP Major facilitator Superfamily
HCIGHHLN_01324 6.2e-163 EGP Major facilitator Superfamily
HCIGHHLN_01325 1.2e-123 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCIGHHLN_01326 4.4e-197 XK27_00915 C Luciferase-like monooxygenase
HCIGHHLN_01327 4.3e-251 emrY EGP Major facilitator Superfamily
HCIGHHLN_01328 2.3e-260 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HCIGHHLN_01329 3.4e-35 yozE S Belongs to the UPF0346 family
HCIGHHLN_01330 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HCIGHHLN_01331 1.1e-151 ypmR E GDSL-like Lipase/Acylhydrolase
HCIGHHLN_01332 5.1e-148 DegV S EDD domain protein, DegV family
HCIGHHLN_01333 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HCIGHHLN_01334 1e-189 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCIGHHLN_01335 0.0 yfmR S ABC transporter, ATP-binding protein
HCIGHHLN_01336 9.6e-85
HCIGHHLN_01337 1.1e-228 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HCIGHHLN_01338 2.1e-143 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCIGHHLN_01339 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
HCIGHHLN_01340 3.3e-215 S Tetratricopeptide repeat protein
HCIGHHLN_01341 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HCIGHHLN_01342 2.7e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HCIGHHLN_01343 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
HCIGHHLN_01344 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HCIGHHLN_01345 2e-19 M Lysin motif
HCIGHHLN_01346 2.1e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCIGHHLN_01347 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
HCIGHHLN_01348 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HCIGHHLN_01349 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCIGHHLN_01350 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HCIGHHLN_01351 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HCIGHHLN_01352 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HCIGHHLN_01353 5.5e-164 xerD D recombinase XerD
HCIGHHLN_01354 2.9e-170 cvfB S S1 domain
HCIGHHLN_01355 1.5e-74 yeaL S Protein of unknown function (DUF441)
HCIGHHLN_01356 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HCIGHHLN_01357 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HCIGHHLN_01358 0.0 dnaE 2.7.7.7 L DNA polymerase
HCIGHHLN_01359 7.3e-29 S Protein of unknown function (DUF2929)
HCIGHHLN_01360 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCIGHHLN_01361 1.4e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HCIGHHLN_01362 3.8e-198 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HCIGHHLN_01363 1.6e-126 trmK 2.1.1.217 S SAM-dependent methyltransferase
HCIGHHLN_01364 3.8e-221 M O-Antigen ligase
HCIGHHLN_01365 1.2e-119 drrB U ABC-2 type transporter
HCIGHHLN_01366 4.3e-164 drrA V ABC transporter
HCIGHHLN_01367 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_01368 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HCIGHHLN_01369 1.9e-62 P Rhodanese Homology Domain
HCIGHHLN_01370 1.2e-89 yetL K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_01371 2e-208
HCIGHHLN_01372 1.2e-218 I transferase activity, transferring acyl groups other than amino-acyl groups
HCIGHHLN_01373 1.1e-181 C Zinc-binding dehydrogenase
HCIGHHLN_01374 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
HCIGHHLN_01375 5.2e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCIGHHLN_01376 1.3e-241 EGP Major facilitator Superfamily
HCIGHHLN_01377 4.3e-77 K Transcriptional regulator
HCIGHHLN_01378 3.7e-210 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HCIGHHLN_01379 4.7e-311 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCIGHHLN_01380 8e-137 K DeoR C terminal sensor domain
HCIGHHLN_01381 1.7e-108 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
HCIGHHLN_01382 3.5e-70 yneH 1.20.4.1 P ArsC family
HCIGHHLN_01383 4.1e-68 S Protein of unknown function (DUF1722)
HCIGHHLN_01384 2e-112 GM epimerase
HCIGHHLN_01385 0.0 CP_1020 S Zinc finger, swim domain protein
HCIGHHLN_01386 1.5e-118 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
HCIGHHLN_01387 7.3e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCIGHHLN_01388 2.5e-127 K Helix-turn-helix domain, rpiR family
HCIGHHLN_01389 2.6e-160 S Alpha beta hydrolase
HCIGHHLN_01390 4.5e-112 GM NmrA-like family
HCIGHHLN_01391 9.8e-79 S Uncharacterized protein conserved in bacteria (DUF2255)
HCIGHHLN_01392 1.9e-161 K Transcriptional regulator
HCIGHHLN_01393 6.7e-173 C nadph quinone reductase
HCIGHHLN_01394 2.5e-13 S Alpha beta hydrolase
HCIGHHLN_01395 2.5e-269 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCIGHHLN_01396 3.6e-103 desR K helix_turn_helix, Lux Regulon
HCIGHHLN_01397 1.5e-203 desK 2.7.13.3 T Histidine kinase
HCIGHHLN_01398 1.3e-134 yvfS V ABC-2 type transporter
HCIGHHLN_01399 2.6e-158 yvfR V ABC transporter
HCIGHHLN_01401 6e-82 K Acetyltransferase (GNAT) domain
HCIGHHLN_01402 2.1e-73 K MarR family
HCIGHHLN_01403 3.8e-114 S Psort location CytoplasmicMembrane, score
HCIGHHLN_01404 3.9e-162 V ABC transporter, ATP-binding protein
HCIGHHLN_01405 2.3e-128 S ABC-2 family transporter protein
HCIGHHLN_01406 3.6e-199
HCIGHHLN_01407 9.2e-203
HCIGHHLN_01408 4.8e-165 ytrB V ABC transporter, ATP-binding protein
HCIGHHLN_01409 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
HCIGHHLN_01410 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCIGHHLN_01411 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCIGHHLN_01412 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HCIGHHLN_01413 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HCIGHHLN_01414 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
HCIGHHLN_01415 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCIGHHLN_01416 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HCIGHHLN_01417 2.5e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCIGHHLN_01418 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
HCIGHHLN_01419 2.6e-71 yqeY S YqeY-like protein
HCIGHHLN_01420 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HCIGHHLN_01421 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HCIGHHLN_01422 1.7e-128 C Enoyl-(Acyl carrier protein) reductase
HCIGHHLN_01423 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HCIGHHLN_01424 2.9e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HCIGHHLN_01425 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HCIGHHLN_01426 1.6e-99 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIGHHLN_01427 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HCIGHHLN_01428 8.3e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
HCIGHHLN_01429 1.9e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HCIGHHLN_01430 1.8e-84 hmpT S Pfam:DUF3816
HCIGHHLN_01431 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCIGHHLN_01432 3.9e-111
HCIGHHLN_01433 2.9e-150 M Glycosyl hydrolases family 25
HCIGHHLN_01434 2e-143 yvpB S Peptidase_C39 like family
HCIGHHLN_01435 1.1e-92 yueI S Protein of unknown function (DUF1694)
HCIGHHLN_01436 1.6e-115 S Protein of unknown function (DUF554)
HCIGHHLN_01437 6.4e-148 KT helix_turn_helix, mercury resistance
HCIGHHLN_01439 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HCIGHHLN_01440 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
HCIGHHLN_01441 1.4e-107 L Integrase
HCIGHHLN_01442 4.9e-16
HCIGHHLN_01443 5.9e-41
HCIGHHLN_01444 6e-31 cspA K Cold shock protein
HCIGHHLN_01445 1e-55
HCIGHHLN_01446 1.5e-42 S COG NOG38524 non supervised orthologous group
HCIGHHLN_01447 3.4e-35
HCIGHHLN_01448 1.4e-92 Z012_04635 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_01449 3.5e-101 EGP Major facilitator Superfamily
HCIGHHLN_01450 3e-20 S Protein of unknown function (DUF1617)
HCIGHHLN_01455 6.1e-78 ps461 M Glycosyl hydrolases family 25
HCIGHHLN_01456 1.5e-79
HCIGHHLN_01457 1.7e-11 L Initiator Replication protein
HCIGHHLN_01458 3.5e-79 L Initiator Replication protein
HCIGHHLN_01459 3.6e-143 virB6 U Conjugal transfer protein
HCIGHHLN_01460 2.1e-12
HCIGHHLN_01461 3.6e-58 virB5 U type IV secretion
HCIGHHLN_01462 3.3e-242 G MFS/sugar transport protein
HCIGHHLN_01463 2e-126 tnp L DDE domain
HCIGHHLN_01464 4.6e-41 ble E bleomycin resistance protein
HCIGHHLN_01465 5.1e-69 ccrA 3.5.2.6 S Metallo-beta-lactamase superfamily
HCIGHHLN_01466 1.7e-63
HCIGHHLN_01467 1.6e-75 yugI 5.3.1.9 J general stress protein
HCIGHHLN_01468 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCIGHHLN_01469 3e-119 dedA S SNARE-like domain protein
HCIGHHLN_01470 2.1e-117 S Protein of unknown function (DUF1461)
HCIGHHLN_01471 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HCIGHHLN_01472 1.5e-80 yutD S Protein of unknown function (DUF1027)
HCIGHHLN_01473 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HCIGHHLN_01474 4.4e-117 S Calcineurin-like phosphoesterase
HCIGHHLN_01475 5.6e-253 cycA E Amino acid permease
HCIGHHLN_01476 7.8e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCIGHHLN_01477 3.6e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HCIGHHLN_01479 4.5e-88 S Prokaryotic N-terminal methylation motif
HCIGHHLN_01480 8.6e-20
HCIGHHLN_01481 3.5e-82 gspG NU general secretion pathway protein
HCIGHHLN_01482 5.5e-43 comGC U competence protein ComGC
HCIGHHLN_01483 1.9e-189 comGB NU type II secretion system
HCIGHHLN_01484 5.6e-175 comGA NU Type II IV secretion system protein
HCIGHHLN_01485 1.4e-159 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCIGHHLN_01486 8.3e-131 yebC K Transcriptional regulatory protein
HCIGHHLN_01487 5.4e-50 S DsrE/DsrF-like family
HCIGHHLN_01488 5.2e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
HCIGHHLN_01489 1.9e-181 ccpA K catabolite control protein A
HCIGHHLN_01490 1.7e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HCIGHHLN_01491 2.5e-80 K helix_turn_helix, mercury resistance
HCIGHHLN_01492 2.8e-56
HCIGHHLN_01493 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HCIGHHLN_01494 2.6e-158 ykuT M mechanosensitive ion channel
HCIGHHLN_01495 1.1e-225 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HCIGHHLN_01496 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HCIGHHLN_01497 6.5e-87 ykuL S (CBS) domain
HCIGHHLN_01498 1.2e-94 S Phosphoesterase
HCIGHHLN_01499 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCIGHHLN_01500 4.1e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCIGHHLN_01501 7.6e-126 yslB S Protein of unknown function (DUF2507)
HCIGHHLN_01502 3.3e-52 trxA O Belongs to the thioredoxin family
HCIGHHLN_01503 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HCIGHHLN_01504 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HCIGHHLN_01505 1.6e-48 yrzB S Belongs to the UPF0473 family
HCIGHHLN_01506 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCIGHHLN_01507 2.4e-43 yrzL S Belongs to the UPF0297 family
HCIGHHLN_01508 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCIGHHLN_01509 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HCIGHHLN_01510 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HCIGHHLN_01511 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCIGHHLN_01512 2.8e-29 yajC U Preprotein translocase
HCIGHHLN_01513 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCIGHHLN_01514 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HCIGHHLN_01515 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCIGHHLN_01516 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCIGHHLN_01517 2.7e-91
HCIGHHLN_01518 0.0 S Bacterial membrane protein YfhO
HCIGHHLN_01519 1.3e-72
HCIGHHLN_01520 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HCIGHHLN_01521 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HCIGHHLN_01522 2.7e-154 ymdB S YmdB-like protein
HCIGHHLN_01523 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
HCIGHHLN_01524 5.2e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCIGHHLN_01525 7.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
HCIGHHLN_01526 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCIGHHLN_01527 5.7e-110 ymfM S Helix-turn-helix domain
HCIGHHLN_01528 7.1e-250 ymfH S Peptidase M16
HCIGHHLN_01529 6.5e-232 ymfF S Peptidase M16 inactive domain protein
HCIGHHLN_01530 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
HCIGHHLN_01531 1.5e-155 aatB ET ABC transporter substrate-binding protein
HCIGHHLN_01532 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCIGHHLN_01533 4.6e-109 glnP P ABC transporter permease
HCIGHHLN_01534 1.2e-146 minD D Belongs to the ParA family
HCIGHHLN_01535 4.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HCIGHHLN_01536 1.2e-88 mreD M rod shape-determining protein MreD
HCIGHHLN_01537 2.6e-144 mreC M Involved in formation and maintenance of cell shape
HCIGHHLN_01538 2.8e-161 mreB D cell shape determining protein MreB
HCIGHHLN_01539 6.6e-116 radC L DNA repair protein
HCIGHHLN_01540 1.4e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCIGHHLN_01541 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCIGHHLN_01542 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HCIGHHLN_01543 2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HCIGHHLN_01544 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HCIGHHLN_01545 1.7e-218 iscS2 2.8.1.7 E Aminotransferase class V
HCIGHHLN_01546 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HCIGHHLN_01547 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
HCIGHHLN_01548 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCIGHHLN_01549 5.2e-113 yktB S Belongs to the UPF0637 family
HCIGHHLN_01550 7.3e-80 yueI S Protein of unknown function (DUF1694)
HCIGHHLN_01551 3.1e-110 S Protein of unknown function (DUF1648)
HCIGHHLN_01552 1.7e-44 czrA K Helix-turn-helix domain
HCIGHHLN_01553 5.7e-231 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HCIGHHLN_01554 9.2e-42 2.7.1.191 G PTS system fructose IIA component
HCIGHHLN_01555 2.7e-104 G PTS system mannose fructose sorbose family IID component
HCIGHHLN_01556 3.6e-103 G PTS system sorbose-specific iic component
HCIGHHLN_01557 6e-66 2.7.1.191 G PTS system sorbose subfamily IIB component
HCIGHHLN_01558 5.9e-95 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCIGHHLN_01559 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HCIGHHLN_01560 8e-238 rarA L recombination factor protein RarA
HCIGHHLN_01561 1.5e-38
HCIGHHLN_01562 6.2e-82 usp6 T universal stress protein
HCIGHHLN_01563 6.1e-205 bla2 3.5.2.6 V Beta-lactamase enzyme family
HCIGHHLN_01564 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_01565 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HCIGHHLN_01566 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCIGHHLN_01567 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HCIGHHLN_01568 1.6e-177 S Protein of unknown function (DUF2785)
HCIGHHLN_01569 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
HCIGHHLN_01570 2.2e-148 metQ M Belongs to the nlpA lipoprotein family
HCIGHHLN_01571 1.4e-111 metI U ABC transporter permease
HCIGHHLN_01572 2.6e-186 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCIGHHLN_01573 3.6e-48 gcsH2 E glycine cleavage
HCIGHHLN_01574 9.3e-220 rodA D Belongs to the SEDS family
HCIGHHLN_01575 3.3e-33 S Protein of unknown function (DUF2969)
HCIGHHLN_01576 7.9e-44 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HCIGHHLN_01577 2.7e-180 mbl D Cell shape determining protein MreB Mrl
HCIGHHLN_01578 2.1e-102 J Acetyltransferase (GNAT) domain
HCIGHHLN_01579 4.4e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCIGHHLN_01580 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCIGHHLN_01581 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCIGHHLN_01582 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCIGHHLN_01583 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCIGHHLN_01584 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIGHHLN_01585 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCIGHHLN_01586 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCIGHHLN_01587 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HCIGHHLN_01588 5e-232 pyrP F Permease
HCIGHHLN_01589 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCIGHHLN_01590 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HCIGHHLN_01591 6.9e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HCIGHHLN_01592 2.3e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCIGHHLN_01593 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCIGHHLN_01594 9.3e-109 tdk 2.7.1.21 F thymidine kinase
HCIGHHLN_01595 1.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HCIGHHLN_01596 2.2e-136 cobQ S glutamine amidotransferase
HCIGHHLN_01597 3.4e-196 manA 5.3.1.8 G mannose-6-phosphate isomerase
HCIGHHLN_01598 1.4e-192 ampC V Beta-lactamase
HCIGHHLN_01599 1.4e-29
HCIGHHLN_01600 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HCIGHHLN_01601 1.9e-58
HCIGHHLN_01602 4.4e-127
HCIGHHLN_01603 0.0 yfiC V ABC transporter
HCIGHHLN_01604 0.0 ycfI V ABC transporter, ATP-binding protein
HCIGHHLN_01605 3.3e-65 S Protein of unknown function (DUF1093)
HCIGHHLN_01606 3.8e-135 yxkH G Polysaccharide deacetylase
HCIGHHLN_01609 8.9e-30
HCIGHHLN_01611 2e-38
HCIGHHLN_01612 1.4e-43
HCIGHHLN_01613 7.3e-83 K MarR family
HCIGHHLN_01614 0.0 bztC D nuclear chromosome segregation
HCIGHHLN_01615 6.3e-292 M MucBP domain
HCIGHHLN_01616 2.7e-16
HCIGHHLN_01617 7.2e-17
HCIGHHLN_01618 1.6e-16
HCIGHHLN_01619 1.6e-16
HCIGHHLN_01620 1.6e-16
HCIGHHLN_01621 1.9e-18
HCIGHHLN_01622 1.6e-16
HCIGHHLN_01623 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
HCIGHHLN_01624 1.8e-271 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIGHHLN_01625 0.0 macB3 V ABC transporter, ATP-binding protein
HCIGHHLN_01626 6.8e-24
HCIGHHLN_01627 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
HCIGHHLN_01628 9.7e-155 glcU U sugar transport
HCIGHHLN_01629 3.2e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HCIGHHLN_01630 2.9e-287 yclK 2.7.13.3 T Histidine kinase
HCIGHHLN_01631 1.6e-134 K response regulator
HCIGHHLN_01632 3e-243 XK27_08635 S UPF0210 protein
HCIGHHLN_01633 5.2e-38 gcvR T Belongs to the UPF0237 family
HCIGHHLN_01634 1.5e-169 EG EamA-like transporter family
HCIGHHLN_01636 7.7e-92 S ECF-type riboflavin transporter, S component
HCIGHHLN_01637 8.6e-48
HCIGHHLN_01638 6.4e-213 yceI EGP Major facilitator Superfamily
HCIGHHLN_01639 9.4e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
HCIGHHLN_01640 3.8e-23
HCIGHHLN_01642 5.5e-158 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_01643 2.8e-173 ykfC 3.4.14.13 M NlpC/P60 family
HCIGHHLN_01644 6.6e-81 K AsnC family
HCIGHHLN_01645 9.9e-35
HCIGHHLN_01646 5.1e-34
HCIGHHLN_01647 3.9e-218 2.7.7.65 T diguanylate cyclase
HCIGHHLN_01648 7.8e-296 S ABC transporter, ATP-binding protein
HCIGHHLN_01649 2e-106 3.2.2.20 K acetyltransferase
HCIGHHLN_01650 9.8e-82 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HCIGHHLN_01651 2.7e-39
HCIGHHLN_01652 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HCIGHHLN_01653 1.4e-189 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIGHHLN_01654 1.3e-162 degV S Uncharacterised protein, DegV family COG1307
HCIGHHLN_01655 5.6e-231 hom1 1.1.1.3 E Homoserine dehydrogenase
HCIGHHLN_01656 5.8e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
HCIGHHLN_01657 1.4e-164 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
HCIGHHLN_01658 1.4e-176 XK27_08835 S ABC transporter
HCIGHHLN_01659 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HCIGHHLN_01660 5.8e-138 XK27_08845 S ABC transporter, ATP-binding protein
HCIGHHLN_01661 2.5e-258 npr 1.11.1.1 C NADH oxidase
HCIGHHLN_01662 1.4e-156 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HCIGHHLN_01663 1.4e-136 terC P membrane
HCIGHHLN_01664 2.9e-83 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCIGHHLN_01665 1.2e-197 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCIGHHLN_01666 2.2e-51 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
HCIGHHLN_01667 2.5e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCIGHHLN_01668 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCIGHHLN_01669 3.5e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HCIGHHLN_01670 1.8e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCIGHHLN_01671 3e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HCIGHHLN_01672 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCIGHHLN_01673 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HCIGHHLN_01674 2.8e-213 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HCIGHHLN_01675 1.3e-161 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
HCIGHHLN_01676 5.1e-215 ysaA V RDD family
HCIGHHLN_01677 7.6e-166 corA P CorA-like Mg2+ transporter protein
HCIGHHLN_01678 2.1e-55 S Domain of unknown function (DU1801)
HCIGHHLN_01679 5.9e-91 rmeB K transcriptional regulator, MerR family
HCIGHHLN_01680 6.5e-148 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_01681 8.6e-98 J glyoxalase III activity
HCIGHHLN_01682 4e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCIGHHLN_01683 2.4e-186 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCIGHHLN_01684 3.7e-34
HCIGHHLN_01685 3.2e-112 S Protein of unknown function (DUF1211)
HCIGHHLN_01686 0.0 ydgH S MMPL family
HCIGHHLN_01687 4.8e-288 M domain protein
HCIGHHLN_01688 3.9e-75 yjcF S Acetyltransferase (GNAT) domain
HCIGHHLN_01689 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HCIGHHLN_01690 0.0 glpQ 3.1.4.46 C phosphodiesterase
HCIGHHLN_01691 2.3e-184 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HCIGHHLN_01692 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_01693 2.8e-182 3.6.4.13 S domain, Protein
HCIGHHLN_01694 3.6e-168 S Polyphosphate kinase 2 (PPK2)
HCIGHHLN_01695 2.5e-98 drgA C Nitroreductase family
HCIGHHLN_01696 3.1e-178 iunH2 3.2.2.1 F nucleoside hydrolase
HCIGHHLN_01697 1.7e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCIGHHLN_01698 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_01699 2.3e-157 ccpB 5.1.1.1 K lacI family
HCIGHHLN_01700 8.1e-117 K Helix-turn-helix domain, rpiR family
HCIGHHLN_01701 1.3e-176 S Oxidoreductase family, NAD-binding Rossmann fold
HCIGHHLN_01702 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
HCIGHHLN_01703 0.0 yjcE P Sodium proton antiporter
HCIGHHLN_01704 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCIGHHLN_01705 3.7e-107 pncA Q Isochorismatase family
HCIGHHLN_01706 2.7e-132
HCIGHHLN_01707 5.1e-125 skfE V ABC transporter
HCIGHHLN_01708 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
HCIGHHLN_01709 1.2e-45 S Enterocin A Immunity
HCIGHHLN_01710 7e-175 D Alpha beta
HCIGHHLN_01711 0.0 pepF2 E Oligopeptidase F
HCIGHHLN_01712 1.3e-72 K Transcriptional regulator
HCIGHHLN_01713 2.3e-164
HCIGHHLN_01714 5.4e-59
HCIGHHLN_01715 1.8e-33
HCIGHHLN_01716 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIGHHLN_01717 1.2e-67
HCIGHHLN_01718 8.4e-145 yjfP S Dienelactone hydrolase family
HCIGHHLN_01719 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
HCIGHHLN_01720 4.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HCIGHHLN_01721 5.2e-47
HCIGHHLN_01722 6.3e-45
HCIGHHLN_01723 5e-82 yybC S Protein of unknown function (DUF2798)
HCIGHHLN_01724 1.7e-73
HCIGHHLN_01725 4e-60
HCIGHHLN_01726 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
HCIGHHLN_01727 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
HCIGHHLN_01728 3e-72 G PTS system fructose IIA component
HCIGHHLN_01729 3.2e-147 G PTS system mannose/fructose/sorbose family IID component
HCIGHHLN_01730 4.7e-143 agaC G PTS system sorbose-specific iic component
HCIGHHLN_01731 6.6e-84 agaB 2.7.1.191 K PTS system sorbose subfamily IIB component
HCIGHHLN_01732 2e-129 K UTRA domain
HCIGHHLN_01733 1.6e-79 uspA T universal stress protein
HCIGHHLN_01734 1.9e-156 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HCIGHHLN_01735 1.7e-48 K Cro/C1-type HTH DNA-binding domain
HCIGHHLN_01736 3.3e-21 S Protein of unknown function (DUF2929)
HCIGHHLN_01737 3e-223 lsgC M Glycosyl transferases group 1
HCIGHHLN_01738 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCIGHHLN_01739 1.2e-160 S Putative esterase
HCIGHHLN_01740 2.4e-130 gntR2 K Transcriptional regulator
HCIGHHLN_01741 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCIGHHLN_01742 5.2e-139
HCIGHHLN_01743 1.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCIGHHLN_01744 5.5e-138 rrp8 K LytTr DNA-binding domain
HCIGHHLN_01745 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
HCIGHHLN_01746 1.7e-60
HCIGHHLN_01747 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
HCIGHHLN_01748 4.4e-58
HCIGHHLN_01749 1.8e-240 yhdP S Transporter associated domain
HCIGHHLN_01750 4.9e-87 nrdI F Belongs to the NrdI family
HCIGHHLN_01751 2.6e-270 yjcE P Sodium proton antiporter
HCIGHHLN_01752 1.1e-212 yttB EGP Major facilitator Superfamily
HCIGHHLN_01753 8.6e-63 K helix_turn_helix, mercury resistance
HCIGHHLN_01754 1.8e-173 C Zinc-binding dehydrogenase
HCIGHHLN_01755 8.5e-57 S SdpI/YhfL protein family
HCIGHHLN_01756 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCIGHHLN_01757 1.6e-260 gabR K Bacterial regulatory proteins, gntR family
HCIGHHLN_01758 7.2e-217 patA 2.6.1.1 E Aminotransferase
HCIGHHLN_01759 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCIGHHLN_01760 3e-18
HCIGHHLN_01761 1.7e-126 S membrane transporter protein
HCIGHHLN_01762 9.5e-161 mleR K LysR family
HCIGHHLN_01763 5.6e-115 ylbE GM NAD(P)H-binding
HCIGHHLN_01764 2.4e-95 wecD K Acetyltransferase (GNAT) family
HCIGHHLN_01765 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HCIGHHLN_01766 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HCIGHHLN_01767 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
HCIGHHLN_01768 6.2e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCIGHHLN_01769 3.9e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HCIGHHLN_01770 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCIGHHLN_01771 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HCIGHHLN_01772 1.2e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HCIGHHLN_01773 2.9e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCIGHHLN_01774 1.1e-172 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCIGHHLN_01775 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HCIGHHLN_01776 1e-298 pucR QT Purine catabolism regulatory protein-like family
HCIGHHLN_01777 2.7e-236 pbuX F xanthine permease
HCIGHHLN_01778 4e-221 pbuG S Permease family
HCIGHHLN_01779 5.6e-161 GM NmrA-like family
HCIGHHLN_01780 6.5e-156 T EAL domain
HCIGHHLN_01781 1.9e-92
HCIGHHLN_01782 9.2e-253 pgaC GT2 M Glycosyl transferase
HCIGHHLN_01783 6.9e-124 2.1.1.14 E Methionine synthase
HCIGHHLN_01784 6.4e-216 purD 6.3.4.13 F Belongs to the GARS family
HCIGHHLN_01785 9.5e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCIGHHLN_01786 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HCIGHHLN_01787 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCIGHHLN_01788 7.4e-280 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCIGHHLN_01789 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIGHHLN_01790 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIGHHLN_01791 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HCIGHHLN_01792 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCIGHHLN_01793 3.3e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCIGHHLN_01794 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCIGHHLN_01795 1.5e-223 XK27_09615 1.3.5.4 S reductase
HCIGHHLN_01796 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
HCIGHHLN_01797 4.9e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HCIGHHLN_01798 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HCIGHHLN_01799 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HCIGHHLN_01800 7.5e-149 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_01801 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
HCIGHHLN_01802 1.7e-139 cysA V ABC transporter, ATP-binding protein
HCIGHHLN_01803 0.0 V FtsX-like permease family
HCIGHHLN_01804 8e-42
HCIGHHLN_01805 7.9e-61 gntR1 K Transcriptional regulator, GntR family
HCIGHHLN_01806 6.9e-164 V ABC transporter, ATP-binding protein
HCIGHHLN_01807 5.8e-149
HCIGHHLN_01808 6.7e-81 uspA T universal stress protein
HCIGHHLN_01809 1.2e-35
HCIGHHLN_01810 4.2e-71 gtcA S Teichoic acid glycosylation protein
HCIGHHLN_01811 1.1e-88
HCIGHHLN_01812 9.4e-50
HCIGHHLN_01814 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
HCIGHHLN_01815 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
HCIGHHLN_01816 5.4e-118
HCIGHHLN_01817 1.5e-52
HCIGHHLN_01819 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HCIGHHLN_01820 3.6e-282 thrC 4.2.3.1 E Threonine synthase
HCIGHHLN_01821 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_01822 1.5e-11 mcbG S Pentapeptide repeats (8 copies)
HCIGHHLN_01823 1.7e-111 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCIGHHLN_01824 1.7e-102 3.6.1.13 L Belongs to the Nudix hydrolase family
HCIGHHLN_01825 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
HCIGHHLN_01826 7.5e-135 IQ Enoyl-(Acyl carrier protein) reductase
HCIGHHLN_01827 1.8e-36 XK27_01315 S Protein of unknown function (DUF2829)
HCIGHHLN_01828 1.9e-211 S Bacterial protein of unknown function (DUF871)
HCIGHHLN_01829 2.1e-232 S Sterol carrier protein domain
HCIGHHLN_01830 3.6e-88 niaR S 3H domain
HCIGHHLN_01831 5.6e-264 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCIGHHLN_01832 1.3e-117 K Transcriptional regulator
HCIGHHLN_01833 3.2e-154 V ABC transporter
HCIGHHLN_01834 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
HCIGHHLN_01835 1.1e-245 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HCIGHHLN_01836 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_01837 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_01838 5.1e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HCIGHHLN_01839 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_01840 1.8e-130 gntR K UTRA
HCIGHHLN_01841 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
HCIGHHLN_01842 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCIGHHLN_01843 1.8e-81
HCIGHHLN_01844 9.8e-152 S hydrolase
HCIGHHLN_01845 3.2e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCIGHHLN_01846 8.3e-152 EG EamA-like transporter family
HCIGHHLN_01847 1.3e-176 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HCIGHHLN_01848 1.2e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCIGHHLN_01849 1.5e-233
HCIGHHLN_01850 1.1e-77 fld C Flavodoxin
HCIGHHLN_01851 0.0 M Bacterial Ig-like domain (group 3)
HCIGHHLN_01852 0.0 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
HCIGHHLN_01853 2.7e-32
HCIGHHLN_01854 6.1e-129 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
HCIGHHLN_01855 2.2e-268 ycaM E amino acid
HCIGHHLN_01856 7.9e-79 K Winged helix DNA-binding domain
HCIGHHLN_01857 3.3e-166 S Oxidoreductase, aldo keto reductase family protein
HCIGHHLN_01858 2.7e-160 akr5f 1.1.1.346 S reductase
HCIGHHLN_01859 4.6e-163 K Transcriptional regulator
HCIGHHLN_01861 7.9e-174 L Integrase core domain
HCIGHHLN_01862 6.4e-19 dsbD 1.8.1.8 CO Thiol disulfide Interchange Protein
HCIGHHLN_01863 8e-139 L Transposase IS66 family
HCIGHHLN_01866 5.2e-37
HCIGHHLN_01868 6e-67
HCIGHHLN_01869 1.5e-94 O DnaJ molecular chaperone homology domain
HCIGHHLN_01871 2.4e-41 repA1 S IncFII RepA protein family
HCIGHHLN_01872 6.1e-109 ydiL S CAAX protease self-immunity
HCIGHHLN_01873 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCIGHHLN_01874 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCIGHHLN_01875 0.0 ydaO E amino acid
HCIGHHLN_01876 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
HCIGHHLN_01877 4.3e-145 pstS P Phosphate
HCIGHHLN_01878 1.7e-114 yvyE 3.4.13.9 S YigZ family
HCIGHHLN_01879 5.7e-258 comFA L Helicase C-terminal domain protein
HCIGHHLN_01880 9.1e-124 comFC S Competence protein
HCIGHHLN_01881 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCIGHHLN_01882 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCIGHHLN_01883 3.2e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCIGHHLN_01884 1.2e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HCIGHHLN_01885 1.5e-132 K response regulator
HCIGHHLN_01886 9.2e-251 phoR 2.7.13.3 T Histidine kinase
HCIGHHLN_01887 1.1e-150 pstS P Phosphate
HCIGHHLN_01888 6.8e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HCIGHHLN_01889 1.5e-155 pstA P Phosphate transport system permease protein PstA
HCIGHHLN_01890 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIGHHLN_01891 1e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCIGHHLN_01892 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
HCIGHHLN_01893 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
HCIGHHLN_01894 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HCIGHHLN_01895 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HCIGHHLN_01896 1.9e-163 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCIGHHLN_01897 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HCIGHHLN_01898 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HCIGHHLN_01899 1.9e-124 yliE T Putative diguanylate phosphodiesterase
HCIGHHLN_01900 6.7e-270 nox C NADH oxidase
HCIGHHLN_01901 4.3e-163 G Belongs to the glycosyl hydrolase 8 (cellulase D) family
HCIGHHLN_01902 3.6e-245
HCIGHHLN_01903 1.9e-204 S Protein conserved in bacteria
HCIGHHLN_01904 6.8e-218 ydaM M Glycosyl transferase family group 2
HCIGHHLN_01905 0.0 ydaN S Bacterial cellulose synthase subunit
HCIGHHLN_01906 1e-132 2.7.7.65 T diguanylate cyclase activity
HCIGHHLN_01907 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCIGHHLN_01908 2e-109 yviA S Protein of unknown function (DUF421)
HCIGHHLN_01909 1.1e-61 S Protein of unknown function (DUF3290)
HCIGHHLN_01910 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HCIGHHLN_01911 3.3e-132 yliE T Putative diguanylate phosphodiesterase
HCIGHHLN_01912 3.4e-258 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
HCIGHHLN_01913 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HCIGHHLN_01914 9.2e-212 norA EGP Major facilitator Superfamily
HCIGHHLN_01915 1.2e-117 yfbR S HD containing hydrolase-like enzyme
HCIGHHLN_01916 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCIGHHLN_01917 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCIGHHLN_01918 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCIGHHLN_01919 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCIGHHLN_01920 7.2e-264 argH 4.3.2.1 E argininosuccinate lyase
HCIGHHLN_01921 9.3e-87 S Short repeat of unknown function (DUF308)
HCIGHHLN_01922 3.2e-161 rapZ S Displays ATPase and GTPase activities
HCIGHHLN_01923 2.9e-190 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HCIGHHLN_01924 3.7e-168 whiA K May be required for sporulation
HCIGHHLN_01925 2.6e-305 oppA E ABC transporter, substratebinding protein
HCIGHHLN_01926 1.1e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIGHHLN_01927 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCIGHHLN_01929 4.2e-245 rpoN K Sigma-54 factor, core binding domain
HCIGHHLN_01930 7.3e-189 cggR K Putative sugar-binding domain
HCIGHHLN_01931 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCIGHHLN_01932 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HCIGHHLN_01933 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCIGHHLN_01934 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCIGHHLN_01935 1.3e-133
HCIGHHLN_01936 1.6e-293 clcA P chloride
HCIGHHLN_01937 1.2e-30 secG U Preprotein translocase
HCIGHHLN_01938 1.3e-139 est 3.1.1.1 S Serine aminopeptidase, S33
HCIGHHLN_01939 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HCIGHHLN_01940 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCIGHHLN_01941 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
HCIGHHLN_01942 9.6e-256 glnP P ABC transporter
HCIGHHLN_01943 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCIGHHLN_01944 4.6e-105 yxjI
HCIGHHLN_01945 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_01946 6.3e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCIGHHLN_01947 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HCIGHHLN_01948 1.5e-80 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HCIGHHLN_01949 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HCIGHHLN_01950 1.1e-100 dnaQ 2.7.7.7 L DNA polymerase III
HCIGHHLN_01951 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
HCIGHHLN_01952 2.1e-160 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HCIGHHLN_01953 6.2e-168 murB 1.3.1.98 M Cell wall formation
HCIGHHLN_01954 0.0 yjcE P Sodium proton antiporter
HCIGHHLN_01955 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_01956 2.5e-121 S Protein of unknown function (DUF1361)
HCIGHHLN_01957 2.7e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HCIGHHLN_01958 1.6e-129 ybbR S YbbR-like protein
HCIGHHLN_01959 1e-251 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCIGHHLN_01960 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCIGHHLN_01961 1.3e-122 yliE T EAL domain
HCIGHHLN_01962 1.3e-145 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_01963 3.1e-104 K Bacterial regulatory proteins, tetR family
HCIGHHLN_01964 6e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCIGHHLN_01965 1.5e-52
HCIGHHLN_01966 6e-73
HCIGHHLN_01967 2e-132 1.5.1.39 C nitroreductase
HCIGHHLN_01968 7.5e-153 G Transmembrane secretion effector
HCIGHHLN_01969 4.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HCIGHHLN_01970 5.1e-139
HCIGHHLN_01972 1.9e-71 spxA 1.20.4.1 P ArsC family
HCIGHHLN_01973 1.5e-33
HCIGHHLN_01974 1.1e-89 V VanZ like family
HCIGHHLN_01975 5.6e-240 EGP Major facilitator Superfamily
HCIGHHLN_01976 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCIGHHLN_01977 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCIGHHLN_01978 1.8e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HCIGHHLN_01979 1.9e-152 licD M LicD family
HCIGHHLN_01980 1.3e-82 K Transcriptional regulator
HCIGHHLN_01981 1.5e-19
HCIGHHLN_01982 1.2e-225 pbuG S permease
HCIGHHLN_01983 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIGHHLN_01984 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCIGHHLN_01985 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIGHHLN_01986 5.4e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HCIGHHLN_01987 2e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HCIGHHLN_01988 0.0 oatA I Acyltransferase
HCIGHHLN_01989 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HCIGHHLN_01990 4.3e-68 O OsmC-like protein
HCIGHHLN_01991 7.9e-48
HCIGHHLN_01992 8.2e-252 yfnA E Amino Acid
HCIGHHLN_01993 2.5e-88
HCIGHHLN_01994 1.9e-147 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HCIGHHLN_01995 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HCIGHHLN_01996 1.8e-19
HCIGHHLN_01997 1.5e-103 gmk2 2.7.4.8 F Guanylate kinase
HCIGHHLN_01998 1.3e-81 zur P Belongs to the Fur family
HCIGHHLN_01999 7.1e-12 3.2.1.14 GH18
HCIGHHLN_02000 4.9e-148
HCIGHHLN_02001 8.8e-113 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HCIGHHLN_02002 3e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HCIGHHLN_02003 5.6e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIGHHLN_02004 3.6e-41
HCIGHHLN_02006 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCIGHHLN_02007 7.8e-149 glnH ET ABC transporter substrate-binding protein
HCIGHHLN_02008 1.6e-109 gluC P ABC transporter permease
HCIGHHLN_02009 4e-108 glnP P ABC transporter permease
HCIGHHLN_02010 1e-84 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCIGHHLN_02011 2.1e-154 K CAT RNA binding domain
HCIGHHLN_02012 7.9e-258 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
HCIGHHLN_02013 3.2e-141 G YdjC-like protein
HCIGHHLN_02014 8.3e-246 steT E amino acid
HCIGHHLN_02015 5.7e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_02016 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
HCIGHHLN_02017 2e-71 K MarR family
HCIGHHLN_02018 8.3e-210 EGP Major facilitator Superfamily
HCIGHHLN_02019 3.8e-85 S membrane transporter protein
HCIGHHLN_02020 7.1e-98 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02021 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCIGHHLN_02022 2.9e-78 3.6.1.55 F NUDIX domain
HCIGHHLN_02023 1.3e-48 sugE U Multidrug resistance protein
HCIGHHLN_02024 1.2e-26
HCIGHHLN_02025 2.1e-128 pgm3 G Phosphoglycerate mutase family
HCIGHHLN_02026 4.7e-125 pgm3 G Phosphoglycerate mutase family
HCIGHHLN_02027 0.0 yjbQ P TrkA C-terminal domain protein
HCIGHHLN_02028 5.9e-177 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
HCIGHHLN_02029 1.6e-109 dedA S SNARE associated Golgi protein
HCIGHHLN_02030 0.0 helD 3.6.4.12 L DNA helicase
HCIGHHLN_02031 5e-165 fabK 1.3.1.9 S Nitronate monooxygenase
HCIGHHLN_02032 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HCIGHHLN_02033 8.7e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCIGHHLN_02034 6.2e-50
HCIGHHLN_02035 1.7e-63 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02036 0.0 L AAA domain
HCIGHHLN_02037 5.5e-116 XK27_07075 V CAAX protease self-immunity
HCIGHHLN_02038 5.2e-156 S Cysteine-rich secretory protein family
HCIGHHLN_02039 2.9e-48 K Cro/C1-type HTH DNA-binding domain
HCIGHHLN_02041 1.5e-68 D nuclear chromosome segregation
HCIGHHLN_02042 3.4e-66
HCIGHHLN_02043 3.3e-152 S Domain of unknown function (DUF4767)
HCIGHHLN_02044 1.9e-48
HCIGHHLN_02045 5.7e-38 S MORN repeat
HCIGHHLN_02046 0.0 XK27_09800 I Acyltransferase family
HCIGHHLN_02047 7.1e-37 S Transglycosylase associated protein
HCIGHHLN_02048 2.6e-84
HCIGHHLN_02049 7.2e-23
HCIGHHLN_02050 8.7e-72 asp S Asp23 family, cell envelope-related function
HCIGHHLN_02051 5.3e-72 asp2 S Asp23 family, cell envelope-related function
HCIGHHLN_02052 2.6e-146 Q Fumarylacetoacetate (FAA) hydrolase family
HCIGHHLN_02053 2.7e-156 yjdB S Domain of unknown function (DUF4767)
HCIGHHLN_02054 3.4e-47 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCIGHHLN_02055 1.1e-101 G Glycogen debranching enzyme
HCIGHHLN_02056 0.0 pepN 3.4.11.2 E aminopeptidase
HCIGHHLN_02057 0.0 N Uncharacterized conserved protein (DUF2075)
HCIGHHLN_02058 2.6e-44 S MazG-like family
HCIGHHLN_02059 3e-90 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
HCIGHHLN_02060 0.0 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HCIGHHLN_02061 4.9e-40 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
HCIGHHLN_02063 3.5e-88 S AAA domain
HCIGHHLN_02064 1.5e-138 K sequence-specific DNA binding
HCIGHHLN_02065 3.5e-97 K Helix-turn-helix domain
HCIGHHLN_02066 2.8e-171 K Transcriptional regulator
HCIGHHLN_02067 0.0 1.3.5.4 C FMN_bind
HCIGHHLN_02069 2.3e-81 rmaD K Transcriptional regulator
HCIGHHLN_02070 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HCIGHHLN_02071 2.8e-254 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HCIGHHLN_02072 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
HCIGHHLN_02073 6.7e-278 pipD E Dipeptidase
HCIGHHLN_02074 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HCIGHHLN_02075 1e-41
HCIGHHLN_02076 4.1e-32 L leucine-zipper of insertion element IS481
HCIGHHLN_02077 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCIGHHLN_02078 2.9e-162 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HCIGHHLN_02079 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_02080 4.3e-138 S NADPH-dependent FMN reductase
HCIGHHLN_02081 6.6e-179
HCIGHHLN_02082 4.3e-220 yibE S overlaps another CDS with the same product name
HCIGHHLN_02083 1.3e-126 yibF S overlaps another CDS with the same product name
HCIGHHLN_02084 7.5e-103 3.2.2.20 K FR47-like protein
HCIGHHLN_02085 5e-122 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCIGHHLN_02086 5.6e-49
HCIGHHLN_02087 1.2e-191 nlhH_1 I alpha/beta hydrolase fold
HCIGHHLN_02088 1.9e-253 xylP2 G symporter
HCIGHHLN_02089 5.2e-281 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCIGHHLN_02090 1.6e-219 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HCIGHHLN_02091 0.0 asnB 6.3.5.4 E Asparagine synthase
HCIGHHLN_02092 7.2e-50 azlD S Branched-chain amino acid transport protein (AzlD)
HCIGHHLN_02093 1.3e-120 azlC E branched-chain amino acid
HCIGHHLN_02094 4.4e-35 yyaN K MerR HTH family regulatory protein
HCIGHHLN_02095 3.2e-105
HCIGHHLN_02097 9.4e-31
HCIGHHLN_02098 1.4e-117 S Domain of unknown function (DUF4811)
HCIGHHLN_02099 7e-270 lmrB EGP Major facilitator Superfamily
HCIGHHLN_02100 1.7e-84 merR K MerR HTH family regulatory protein
HCIGHHLN_02101 5.8e-58
HCIGHHLN_02102 2e-120 sirR K iron dependent repressor
HCIGHHLN_02103 6e-31 cspC K Cold shock protein
HCIGHHLN_02104 1.5e-130 thrE S Putative threonine/serine exporter
HCIGHHLN_02105 2.2e-76 S Threonine/Serine exporter, ThrE
HCIGHHLN_02106 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HCIGHHLN_02107 2.3e-119 lssY 3.6.1.27 I phosphatase
HCIGHHLN_02108 2e-154 I alpha/beta hydrolase fold
HCIGHHLN_02109 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
HCIGHHLN_02110 4.2e-92 K Transcriptional regulator
HCIGHHLN_02111 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HCIGHHLN_02112 1.5e-264 lysP E amino acid
HCIGHHLN_02113 1.6e-113 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HCIGHHLN_02114 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HCIGHHLN_02115 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCIGHHLN_02126 5.5e-08
HCIGHHLN_02130 6.9e-78 ctsR K Belongs to the CtsR family
HCIGHHLN_02131 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCIGHHLN_02132 1.3e-108 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02133 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIGHHLN_02134 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIGHHLN_02135 6.6e-114 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HCIGHHLN_02136 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCIGHHLN_02137 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCIGHHLN_02138 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCIGHHLN_02139 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HCIGHHLN_02140 4.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCIGHHLN_02141 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
HCIGHHLN_02142 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCIGHHLN_02143 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCIGHHLN_02144 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCIGHHLN_02145 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCIGHHLN_02146 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCIGHHLN_02147 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCIGHHLN_02148 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
HCIGHHLN_02149 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCIGHHLN_02150 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCIGHHLN_02151 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCIGHHLN_02152 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCIGHHLN_02153 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCIGHHLN_02154 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCIGHHLN_02155 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCIGHHLN_02156 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCIGHHLN_02157 2.2e-24 rpmD J Ribosomal protein L30
HCIGHHLN_02158 6.3e-70 rplO J Binds to the 23S rRNA
HCIGHHLN_02159 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCIGHHLN_02160 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCIGHHLN_02161 3.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCIGHHLN_02162 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCIGHHLN_02163 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCIGHHLN_02164 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCIGHHLN_02165 2.1e-61 rplQ J Ribosomal protein L17
HCIGHHLN_02166 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HCIGHHLN_02167 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
HCIGHHLN_02168 3.2e-86 ynhH S NusG domain II
HCIGHHLN_02169 0.0 ndh 1.6.99.3 C NADH dehydrogenase
HCIGHHLN_02170 6e-142 cad S FMN_bind
HCIGHHLN_02171 1.5e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCIGHHLN_02172 4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIGHHLN_02173 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIGHHLN_02174 5.5e-144 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HCIGHHLN_02175 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCIGHHLN_02176 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCIGHHLN_02177 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
HCIGHHLN_02178 3.4e-163 degV S Uncharacterised protein, DegV family COG1307
HCIGHHLN_02179 7.4e-184 ywhK S Membrane
HCIGHHLN_02180 1.1e-203 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCIGHHLN_02181 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCIGHHLN_02182 5.7e-166 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCIGHHLN_02183 2e-183 aroF 2.5.1.54 E DAHP synthetase I family
HCIGHHLN_02184 2e-197 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCIGHHLN_02185 8e-263 P Sodium:sulfate symporter transmembrane region
HCIGHHLN_02186 1.6e-52 yitW S Iron-sulfur cluster assembly protein
HCIGHHLN_02187 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
HCIGHHLN_02188 8.9e-178 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
HCIGHHLN_02189 5.9e-199 K Helix-turn-helix domain
HCIGHHLN_02190 3.6e-154 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HCIGHHLN_02191 4.5e-132 mntB 3.6.3.35 P ABC transporter
HCIGHHLN_02192 4.8e-141 mtsB U ABC 3 transport family
HCIGHHLN_02193 1.2e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
HCIGHHLN_02194 3.1e-50
HCIGHHLN_02195 4.6e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HCIGHHLN_02196 8.3e-260 citP P Sodium:sulfate symporter transmembrane region
HCIGHHLN_02197 2.9e-179 citR K sugar-binding domain protein
HCIGHHLN_02198 7.9e-208 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
HCIGHHLN_02199 3.3e-189 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HCIGHHLN_02200 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
HCIGHHLN_02201 2.7e-163 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HCIGHHLN_02202 4.6e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HCIGHHLN_02203 3e-179 L PFAM Integrase, catalytic core
HCIGHHLN_02204 7e-26 K sequence-specific DNA binding
HCIGHHLN_02206 5.8e-57 ssb L Single-strand binding protein family
HCIGHHLN_02207 1.6e-33 3.4.21.53 O protein catabolic process
HCIGHHLN_02208 5.5e-93 virD4 U Type IV secretory pathway, VirD4 components
HCIGHHLN_02209 2.7e-64 ylpA S Enterobacterial TraT complement resistance protein
HCIGHHLN_02210 5.8e-205 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HCIGHHLN_02211 4.2e-95 C Alcohol dehydrogenase GroES-like domain
HCIGHHLN_02212 7.2e-42 C Alcohol dehydrogenase GroES-like domain
HCIGHHLN_02213 3.4e-42 K HxlR-like helix-turn-helix
HCIGHHLN_02214 2.7e-108 ydeA S intracellular protease amidase
HCIGHHLN_02215 6.5e-44 S Protein of unknown function (DUF3781)
HCIGHHLN_02216 2e-209 S Membrane
HCIGHHLN_02217 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_02218 1.4e-47 ulaB 2.7.1.194, 2.7.1.200 G protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HCIGHHLN_02219 5.8e-234 ulaA 2.7.1.194 S PTS system sugar-specific permease component
HCIGHHLN_02220 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCIGHHLN_02221 1.1e-65 S Protein of unknown function (DUF1093)
HCIGHHLN_02222 0.0 bglF 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_02223 3.8e-292 arbB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02224 1.9e-147 licT2 K CAT RNA binding domain
HCIGHHLN_02226 1.9e-30
HCIGHHLN_02227 1.7e-84 dps P Belongs to the Dps family
HCIGHHLN_02228 6.3e-135 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HCIGHHLN_02229 2.6e-276 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
HCIGHHLN_02230 1.7e-284 1.3.5.4 C FAD binding domain
HCIGHHLN_02231 7.9e-163 K LysR substrate binding domain
HCIGHHLN_02232 1.5e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HCIGHHLN_02233 2.7e-291 yjcE P Sodium proton antiporter
HCIGHHLN_02234 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCIGHHLN_02235 2.1e-117 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02236 1.7e-111 NU Mycoplasma protein of unknown function, DUF285
HCIGHHLN_02237 8.5e-37 NU Mycoplasma protein of unknown function, DUF285
HCIGHHLN_02238 9.6e-90 S WxL domain surface cell wall-binding
HCIGHHLN_02239 8.6e-177 S Bacterial protein of unknown function (DUF916)
HCIGHHLN_02240 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HCIGHHLN_02241 1.6e-64 K helix_turn_helix, mercury resistance
HCIGHHLN_02242 3.4e-152 IQ Enoyl-(Acyl carrier protein) reductase
HCIGHHLN_02243 4.3e-69 maa S transferase hexapeptide repeat
HCIGHHLN_02244 2.5e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_02245 8.3e-165 GM NmrA-like family
HCIGHHLN_02246 5.4e-92 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02247 3.5e-172 fhuG U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIGHHLN_02248 9.5e-178 sirB U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HCIGHHLN_02249 1.1e-144 fhuC 3.6.3.34 HP ABC transporter
HCIGHHLN_02250 1.8e-170 fhuD P Periplasmic binding protein
HCIGHHLN_02251 4.3e-109 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02252 2.3e-252 yfjF U Sugar (and other) transporter
HCIGHHLN_02253 1.5e-180 S Aldo keto reductase
HCIGHHLN_02254 4.1e-101 S Protein of unknown function (DUF1211)
HCIGHHLN_02255 1.2e-191 1.1.1.219 GM Male sterility protein
HCIGHHLN_02256 3.2e-98 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02257 9.8e-132 ydfG S KR domain
HCIGHHLN_02258 3.7e-63 hxlR K HxlR-like helix-turn-helix
HCIGHHLN_02259 1e-47 S Domain of unknown function (DUF1905)
HCIGHHLN_02260 0.0 M Glycosyl hydrolases family 25
HCIGHHLN_02261 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HCIGHHLN_02262 2.2e-168 GM NmrA-like family
HCIGHHLN_02263 7.9e-100 fadR K Bacterial regulatory proteins, tetR family
HCIGHHLN_02265 3e-205 2.7.13.3 T GHKL domain
HCIGHHLN_02266 5.7e-135 K LytTr DNA-binding domain
HCIGHHLN_02267 0.0 asnB 6.3.5.4 E Asparagine synthase
HCIGHHLN_02268 1.4e-94 M ErfK YbiS YcfS YnhG
HCIGHHLN_02269 4.9e-213 ytbD EGP Major facilitator Superfamily
HCIGHHLN_02270 2e-61 K Transcriptional regulator, HxlR family
HCIGHHLN_02271 3.3e-121 M1-1017
HCIGHHLN_02272 1.2e-57 K Transcriptional regulator PadR-like family
HCIGHHLN_02273 3e-116 S Haloacid dehalogenase-like hydrolase
HCIGHHLN_02274 2.3e-116
HCIGHHLN_02275 9.3e-215 NU Mycoplasma protein of unknown function, DUF285
HCIGHHLN_02276 1.1e-62
HCIGHHLN_02277 7.5e-101 S WxL domain surface cell wall-binding
HCIGHHLN_02278 6.2e-188 S Cell surface protein
HCIGHHLN_02279 1.8e-113 S GyrI-like small molecule binding domain
HCIGHHLN_02280 3.8e-69 S Iron-sulphur cluster biosynthesis
HCIGHHLN_02281 1.7e-179 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
HCIGHHLN_02282 1.7e-101 S WxL domain surface cell wall-binding
HCIGHHLN_02283 1.5e-189 S Cell surface protein
HCIGHHLN_02284 4.2e-74
HCIGHHLN_02285 8.4e-263
HCIGHHLN_02286 3.5e-228 hpk9 2.7.13.3 T GHKL domain
HCIGHHLN_02287 2.9e-38 S TfoX C-terminal domain
HCIGHHLN_02288 3e-139 K Helix-turn-helix domain
HCIGHHLN_02289 0.0 M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HCIGHHLN_02290 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCIGHHLN_02291 1.7e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HCIGHHLN_02292 0.0 ctpA 3.6.3.54 P P-type ATPase
HCIGHHLN_02293 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HCIGHHLN_02294 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HCIGHHLN_02295 3.9e-66 lysM M LysM domain
HCIGHHLN_02296 3.6e-266 yjeM E Amino Acid
HCIGHHLN_02297 1.9e-144 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02298 1.4e-69
HCIGHHLN_02300 5e-162 IQ KR domain
HCIGHHLN_02301 6.4e-229 amd 3.5.1.47 E Peptidase family M20/M25/M40
HCIGHHLN_02302 9.1e-177 O protein import
HCIGHHLN_02303 4.8e-311 XK27_09600 V ABC transporter, ATP-binding protein
HCIGHHLN_02304 0.0 V ABC transporter
HCIGHHLN_02305 8.6e-218 ykiI
HCIGHHLN_02306 1.1e-116 GM NAD(P)H-binding
HCIGHHLN_02307 1.9e-138 IQ reductase
HCIGHHLN_02308 3.7e-60 I sulfurtransferase activity
HCIGHHLN_02309 2.7e-78 yphH S Cupin domain
HCIGHHLN_02310 4.7e-93 S Phosphatidylethanolamine-binding protein
HCIGHHLN_02311 1.7e-116 GM NAD(P)H-binding
HCIGHHLN_02312 4.3e-176 C C4-dicarboxylate transmembrane transporter activity
HCIGHHLN_02313 1.4e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_02314 6e-73
HCIGHHLN_02315 2e-166 K Bacterial regulatory helix-turn-helix protein, lysR family
HCIGHHLN_02316 2e-283 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
HCIGHHLN_02317 1.2e-73 S Psort location Cytoplasmic, score
HCIGHHLN_02318 7.4e-219 T diguanylate cyclase
HCIGHHLN_02319 2.6e-120 tag 3.2.2.20 L Methyladenine glycosylase
HCIGHHLN_02320 1.4e-92
HCIGHHLN_02321 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
HCIGHHLN_02322 1.8e-54 nudA S ASCH
HCIGHHLN_02323 6.2e-108 S SdpI/YhfL protein family
HCIGHHLN_02324 4.3e-94 M Lysin motif
HCIGHHLN_02325 2.3e-65 M LysM domain
HCIGHHLN_02326 1e-75 K helix_turn_helix, mercury resistance
HCIGHHLN_02327 2.8e-185 1.1.1.219 GM Male sterility protein
HCIGHHLN_02328 8.3e-281 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02329 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_02330 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_02331 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCIGHHLN_02332 5.3e-150 dicA K Helix-turn-helix domain
HCIGHHLN_02333 3.2e-55
HCIGHHLN_02334 9.8e-160 T Calcineurin-like phosphoesterase superfamily domain
HCIGHHLN_02335 7.4e-64
HCIGHHLN_02336 0.0 P Concanavalin A-like lectin/glucanases superfamily
HCIGHHLN_02337 0.0 yhcA V ABC transporter, ATP-binding protein
HCIGHHLN_02338 1.2e-95 cadD P Cadmium resistance transporter
HCIGHHLN_02339 1e-48 K Transcriptional regulator, ArsR family
HCIGHHLN_02340 1.9e-116 S SNARE associated Golgi protein
HCIGHHLN_02341 1.1e-46
HCIGHHLN_02342 6.8e-72 T Belongs to the universal stress protein A family
HCIGHHLN_02343 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
HCIGHHLN_02344 1.6e-122 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02345 2.8e-82 gtrA S GtrA-like protein
HCIGHHLN_02346 3.5e-114 zmp3 O Zinc-dependent metalloprotease
HCIGHHLN_02347 7e-33
HCIGHHLN_02349 7.1e-212 livJ E Receptor family ligand binding region
HCIGHHLN_02350 6.5e-154 livH U Branched-chain amino acid transport system / permease component
HCIGHHLN_02351 5.3e-141 livM E Branched-chain amino acid transport system / permease component
HCIGHHLN_02352 1.8e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
HCIGHHLN_02353 3.3e-124 livF E ABC transporter
HCIGHHLN_02354 8.5e-39 acuB S Domain in cystathionine beta-synthase and other proteins.
HCIGHHLN_02355 7.6e-55 acuB S Domain in cystathionine beta-synthase and other proteins.
HCIGHHLN_02356 1e-91 S WxL domain surface cell wall-binding
HCIGHHLN_02357 3.6e-188 S Cell surface protein
HCIGHHLN_02358 8.6e-63
HCIGHHLN_02359 3e-260
HCIGHHLN_02360 3.5e-169 XK27_00670 S ABC transporter
HCIGHHLN_02361 7.6e-151 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HCIGHHLN_02362 8.1e-109 cmpC S ATPases associated with a variety of cellular activities
HCIGHHLN_02363 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
HCIGHHLN_02364 1.3e-119 drgA C Nitroreductase family
HCIGHHLN_02365 1.1e-95 rmaB K Transcriptional regulator, MarR family
HCIGHHLN_02366 0.0 lmrA 3.6.3.44 V ABC transporter
HCIGHHLN_02367 2.9e-162 ypbG 2.7.1.2 GK ROK family
HCIGHHLN_02368 1.4e-47 3.6.4.12 K HxlR-like helix-turn-helix
HCIGHHLN_02369 3.2e-115 K Transcriptional regulator C-terminal region
HCIGHHLN_02370 5.2e-178 4.1.1.52 S Amidohydrolase
HCIGHHLN_02371 4.4e-129 E lipolytic protein G-D-S-L family
HCIGHHLN_02372 1.8e-159 yicL EG EamA-like transporter family
HCIGHHLN_02373 1.7e-206 sdrF M Collagen binding domain
HCIGHHLN_02374 9.7e-269 I acetylesterase activity
HCIGHHLN_02375 5.2e-177 S Phosphotransferase system, EIIC
HCIGHHLN_02376 3.7e-134 aroD S Alpha/beta hydrolase family
HCIGHHLN_02377 3.2e-37
HCIGHHLN_02379 2.8e-134 S zinc-ribbon domain
HCIGHHLN_02380 5.1e-265 S response to antibiotic
HCIGHHLN_02381 4.8e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HCIGHHLN_02382 2.4e-243 P Sodium:sulfate symporter transmembrane region
HCIGHHLN_02383 7.1e-164 K LysR substrate binding domain
HCIGHHLN_02384 3.7e-70
HCIGHHLN_02385 4.9e-22
HCIGHHLN_02386 1.5e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCIGHHLN_02387 6.8e-192 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCIGHHLN_02388 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCIGHHLN_02389 2e-80
HCIGHHLN_02390 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HCIGHHLN_02391 2.2e-104 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCIGHHLN_02392 3.1e-127 yliE T EAL domain
HCIGHHLN_02393 6.2e-218 2.7.7.65 T Diguanylate cyclase, GGDEF domain
HCIGHHLN_02394 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HCIGHHLN_02395 5.6e-39 S Cytochrome B5
HCIGHHLN_02396 1.9e-238
HCIGHHLN_02397 2e-129 treR K UTRA
HCIGHHLN_02398 2.2e-159 I alpha/beta hydrolase fold
HCIGHHLN_02399 6.6e-256 npp S type I phosphodiesterase nucleotide pyrophosphatase
HCIGHHLN_02400 1.7e-233 yxiO S Vacuole effluxer Atg22 like
HCIGHHLN_02401 1.7e-173 ropB K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02402 3.7e-208 EGP Major facilitator Superfamily
HCIGHHLN_02403 0.0 uvrA3 L excinuclease ABC
HCIGHHLN_02404 0.0 S Predicted membrane protein (DUF2207)
HCIGHHLN_02405 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
HCIGHHLN_02406 3.2e-308 ybiT S ABC transporter, ATP-binding protein
HCIGHHLN_02407 1.3e-224 S CAAX protease self-immunity
HCIGHHLN_02408 1e-132 2.7.1.89 M Phosphotransferase enzyme family
HCIGHHLN_02409 5.7e-97 2.3.1.128 J Acetyltransferase (GNAT) domain
HCIGHHLN_02410 3.2e-103 speG J Acetyltransferase (GNAT) domain
HCIGHHLN_02411 4e-141 endA F DNA RNA non-specific endonuclease
HCIGHHLN_02412 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_02413 8.1e-111 K Transcriptional regulator (TetR family)
HCIGHHLN_02414 2.9e-165 yhgE V domain protein
HCIGHHLN_02415 6.2e-09
HCIGHHLN_02417 3e-246 EGP Major facilitator Superfamily
HCIGHHLN_02418 0.0 mdlA V ABC transporter
HCIGHHLN_02419 0.0 mdlB V ABC transporter
HCIGHHLN_02421 5.7e-194 C Aldo/keto reductase family
HCIGHHLN_02422 1.9e-102 M Protein of unknown function (DUF3737)
HCIGHHLN_02423 1.1e-222 patB 4.4.1.8 E Aminotransferase, class I
HCIGHHLN_02424 2.3e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HCIGHHLN_02425 1.7e-62
HCIGHHLN_02426 2.4e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCIGHHLN_02427 5.8e-95 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCIGHHLN_02428 6.1e-76 T Belongs to the universal stress protein A family
HCIGHHLN_02429 5.8e-52 L Tn3 transposase DDE domain
HCIGHHLN_02430 2.5e-27
HCIGHHLN_02431 6e-165 yniA G Fructosamine kinase
HCIGHHLN_02432 7.9e-114 3.1.3.18 J HAD-hyrolase-like
HCIGHHLN_02433 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCIGHHLN_02434 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCIGHHLN_02435 9.6e-58
HCIGHHLN_02436 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCIGHHLN_02437 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
HCIGHHLN_02438 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HCIGHHLN_02439 1.4e-49
HCIGHHLN_02440 1.4e-49
HCIGHHLN_02443 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
HCIGHHLN_02444 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCIGHHLN_02445 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HCIGHHLN_02446 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIGHHLN_02447 8.7e-234 dltB M MBOAT, membrane-bound O-acyltransferase family
HCIGHHLN_02448 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIGHHLN_02449 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
HCIGHHLN_02450 1.3e-197 pbpX2 V Beta-lactamase
HCIGHHLN_02451 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCIGHHLN_02452 0.0 dnaK O Heat shock 70 kDa protein
HCIGHHLN_02453 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCIGHHLN_02454 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCIGHHLN_02455 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
HCIGHHLN_02456 1.2e-188 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HCIGHHLN_02457 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCIGHHLN_02458 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HCIGHHLN_02459 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HCIGHHLN_02460 5.3e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCIGHHLN_02461 1e-93
HCIGHHLN_02462 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCIGHHLN_02463 2.5e-264 ydiN 5.4.99.5 G Major Facilitator
HCIGHHLN_02464 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCIGHHLN_02465 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCIGHHLN_02466 1.1e-47 ylxQ J ribosomal protein
HCIGHHLN_02467 9.5e-49 ylxR K Protein of unknown function (DUF448)
HCIGHHLN_02468 3.3e-217 nusA K Participates in both transcription termination and antitermination
HCIGHHLN_02469 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
HCIGHHLN_02470 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HCIGHHLN_02471 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCIGHHLN_02472 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HCIGHHLN_02473 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
HCIGHHLN_02474 6.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCIGHHLN_02475 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCIGHHLN_02476 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCIGHHLN_02477 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCIGHHLN_02478 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
HCIGHHLN_02479 4.7e-134 S Haloacid dehalogenase-like hydrolase
HCIGHHLN_02480 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCIGHHLN_02481 2e-49 yazA L GIY-YIG catalytic domain protein
HCIGHHLN_02482 2.8e-137 yabB 2.1.1.223 L Methyltransferase small domain
HCIGHHLN_02483 2.4e-118 plsC 2.3.1.51 I Acyltransferase
HCIGHHLN_02484 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
HCIGHHLN_02485 2.9e-36 ynzC S UPF0291 protein
HCIGHHLN_02486 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCIGHHLN_02487 5.4e-86
HCIGHHLN_02488 7.1e-217 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HCIGHHLN_02489 1.1e-76
HCIGHHLN_02490 1.3e-66
HCIGHHLN_02491 9.9e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HCIGHHLN_02492 2.1e-100 L Helix-turn-helix domain
HCIGHHLN_02493 1.1e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
HCIGHHLN_02494 2.3e-142 P ATPases associated with a variety of cellular activities
HCIGHHLN_02495 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
HCIGHHLN_02496 4.5e-230 rodA D Cell cycle protein
HCIGHHLN_02499 3.3e-37 S Haemolysin XhlA
HCIGHHLN_02500 1.2e-203 lys M Glycosyl hydrolases family 25
HCIGHHLN_02501 4.1e-54
HCIGHHLN_02504 1.2e-221
HCIGHHLN_02505 1.1e-291 S Phage minor structural protein
HCIGHHLN_02506 6.1e-220 S Phage tail protein
HCIGHHLN_02507 0.0 D NLP P60 protein
HCIGHHLN_02508 1.1e-18
HCIGHHLN_02509 7e-57 S Phage tail assembly chaperone proteins, TAC
HCIGHHLN_02510 1e-108 S Phage tail tube protein
HCIGHHLN_02511 6.4e-58 S Protein of unknown function (DUF806)
HCIGHHLN_02512 2.1e-67 S Bacteriophage HK97-gp10, putative tail-component
HCIGHHLN_02513 6.5e-57 S Phage head-tail joining protein
HCIGHHLN_02514 1.4e-48 S Phage gp6-like head-tail connector protein
HCIGHHLN_02515 3.9e-213 S Phage capsid family
HCIGHHLN_02516 7.9e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HCIGHHLN_02517 6.8e-223 S Phage portal protein
HCIGHHLN_02518 5.6e-26 S Protein of unknown function (DUF1056)
HCIGHHLN_02519 0.0 S Phage Terminase
HCIGHHLN_02520 3e-78 S Phage terminase, small subunit
HCIGHHLN_02523 4.7e-88 L HNH nucleases
HCIGHHLN_02524 1.3e-13 V HNH nucleases
HCIGHHLN_02525 2.7e-87
HCIGHHLN_02526 3.4e-61 S Transcriptional regulator, RinA family
HCIGHHLN_02527 5.4e-47
HCIGHHLN_02529 7.3e-133 pi346 L IstB-like ATP binding protein
HCIGHHLN_02530 5.5e-72 L DnaD domain protein
HCIGHHLN_02533 3.5e-07
HCIGHHLN_02539 1.4e-25
HCIGHHLN_02541 7.1e-93 kilA K BRO family, N-terminal domain
HCIGHHLN_02543 6.1e-25 ps115 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02544 1.5e-36 S Pfam:Peptidase_M78
HCIGHHLN_02549 5.3e-23
HCIGHHLN_02554 2.4e-63 L Belongs to the 'phage' integrase family
HCIGHHLN_02555 1.6e-31
HCIGHHLN_02556 1.5e-143 Q Methyltransferase
HCIGHHLN_02557 8.5e-57 ybjQ S Belongs to the UPF0145 family
HCIGHHLN_02558 2.7e-211 EGP Major facilitator Superfamily
HCIGHHLN_02559 1.5e-103 K Helix-turn-helix domain
HCIGHHLN_02560 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCIGHHLN_02561 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HCIGHHLN_02562 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
HCIGHHLN_02563 4e-139 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCIGHHLN_02564 2.8e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HCIGHHLN_02565 3.2e-46
HCIGHHLN_02566 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HCIGHHLN_02567 1.5e-135 fruR K DeoR C terminal sensor domain
HCIGHHLN_02568 4.6e-171 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HCIGHHLN_02569 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
HCIGHHLN_02570 1.6e-252 cpdA S Calcineurin-like phosphoesterase
HCIGHHLN_02571 1.9e-264 cps4J S Polysaccharide biosynthesis protein
HCIGHHLN_02572 2.7e-177 cps4I M Glycosyltransferase like family 2
HCIGHHLN_02573 5.4e-234
HCIGHHLN_02574 2.9e-190 cps4G M Glycosyltransferase Family 4
HCIGHHLN_02575 1.2e-202 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
HCIGHHLN_02576 2.7e-128 tuaA M Bacterial sugar transferase
HCIGHHLN_02577 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
HCIGHHLN_02578 7.9e-146 ywqE 3.1.3.48 GM PHP domain protein
HCIGHHLN_02579 7.3e-124 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HCIGHHLN_02580 2.9e-126 epsB M biosynthesis protein
HCIGHHLN_02581 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCIGHHLN_02582 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCIGHHLN_02583 9.2e-270 glnPH2 P ABC transporter permease
HCIGHHLN_02584 4.3e-22
HCIGHHLN_02585 9.9e-73 S Iron-sulphur cluster biosynthesis
HCIGHHLN_02586 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HCIGHHLN_02587 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HCIGHHLN_02588 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCIGHHLN_02589 4.1e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCIGHHLN_02590 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCIGHHLN_02591 1.1e-159 S Tetratricopeptide repeat
HCIGHHLN_02592 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIGHHLN_02593 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCIGHHLN_02594 1.3e-192 mdtG EGP Major Facilitator Superfamily
HCIGHHLN_02595 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCIGHHLN_02596 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
HCIGHHLN_02597 3.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HCIGHHLN_02598 0.0 comEC S Competence protein ComEC
HCIGHHLN_02599 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
HCIGHHLN_02600 2.1e-126 comEA L Competence protein ComEA
HCIGHHLN_02601 9.6e-197 ylbL T Belongs to the peptidase S16 family
HCIGHHLN_02602 1.4e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCIGHHLN_02603 1.1e-101 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HCIGHHLN_02604 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HCIGHHLN_02605 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HCIGHHLN_02606 1.6e-205 ftsW D Belongs to the SEDS family
HCIGHHLN_02607 6.3e-293
HCIGHHLN_02608 4.8e-165 ica2 GT2 M Glycosyl transferase family group 2
HCIGHHLN_02609 0.0 typA T GTP-binding protein TypA
HCIGHHLN_02610 4.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HCIGHHLN_02611 3.3e-46 yktA S Belongs to the UPF0223 family
HCIGHHLN_02612 8.1e-163 1.1.1.27 C L-malate dehydrogenase activity
HCIGHHLN_02613 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
HCIGHHLN_02614 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HCIGHHLN_02615 4.5e-180 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HCIGHHLN_02616 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HCIGHHLN_02617 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCIGHHLN_02618 1.6e-85
HCIGHHLN_02619 3.1e-33 ykzG S Belongs to the UPF0356 family
HCIGHHLN_02620 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCIGHHLN_02621 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HCIGHHLN_02622 1.7e-28
HCIGHHLN_02623 2e-107 mltD CBM50 M NlpC P60 family protein
HCIGHHLN_02624 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCIGHHLN_02625 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HCIGHHLN_02626 4e-119 S Repeat protein
HCIGHHLN_02627 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HCIGHHLN_02628 3.8e-268 N domain, Protein
HCIGHHLN_02629 1.7e-193 S Bacterial protein of unknown function (DUF916)
HCIGHHLN_02630 2.3e-120 N WxL domain surface cell wall-binding
HCIGHHLN_02631 2.6e-115 ktrA P domain protein
HCIGHHLN_02632 1.3e-241 ktrB P Potassium uptake protein
HCIGHHLN_02633 9e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HCIGHHLN_02634 4.9e-57 XK27_04120 S Putative amino acid metabolism
HCIGHHLN_02635 1.9e-217 iscS 2.8.1.7 E Aminotransferase class V
HCIGHHLN_02636 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCIGHHLN_02637 4.6e-28
HCIGHHLN_02638 5.6e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HCIGHHLN_02639 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HCIGHHLN_02640 9e-18 S Protein of unknown function (DUF3021)
HCIGHHLN_02641 2.9e-36 K LytTr DNA-binding domain
HCIGHHLN_02642 3.6e-80 cylB U ABC-2 type transporter
HCIGHHLN_02643 8.8e-79 cylA V abc transporter atp-binding protein
HCIGHHLN_02644 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCIGHHLN_02645 1.2e-86 divIVA D DivIVA domain protein
HCIGHHLN_02646 9.9e-146 ylmH S S4 domain protein
HCIGHHLN_02647 1.2e-36 yggT S YGGT family
HCIGHHLN_02648 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCIGHHLN_02649 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCIGHHLN_02650 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HCIGHHLN_02651 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HCIGHHLN_02652 1.5e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCIGHHLN_02653 3.6e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCIGHHLN_02654 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCIGHHLN_02655 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HCIGHHLN_02656 7.5e-54 ftsL D Cell division protein FtsL
HCIGHHLN_02657 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCIGHHLN_02658 1.9e-77 mraZ K Belongs to the MraZ family
HCIGHHLN_02659 1.9e-62 S Protein of unknown function (DUF3397)
HCIGHHLN_02660 4.2e-175 corA P CorA-like Mg2+ transporter protein
HCIGHHLN_02661 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HCIGHHLN_02662 1.4e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCIGHHLN_02663 3.1e-113 ywnB S NAD(P)H-binding
HCIGHHLN_02664 9.8e-210 brnQ U Component of the transport system for branched-chain amino acids
HCIGHHLN_02666 4.1e-161 rrmA 2.1.1.187 H Methyltransferase
HCIGHHLN_02667 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCIGHHLN_02668 4.3e-206 XK27_05220 S AI-2E family transporter
HCIGHHLN_02669 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HCIGHHLN_02670 7.4e-194 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HCIGHHLN_02671 5.1e-116 cutC P Participates in the control of copper homeostasis
HCIGHHLN_02672 8.9e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HCIGHHLN_02673 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCIGHHLN_02674 2.7e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
HCIGHHLN_02675 3.6e-114 yjbH Q Thioredoxin
HCIGHHLN_02676 0.0 pepF E oligoendopeptidase F
HCIGHHLN_02677 7.6e-205 coiA 3.6.4.12 S Competence protein
HCIGHHLN_02678 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HCIGHHLN_02679 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HCIGHHLN_02680 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
HCIGHHLN_02681 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HCIGHHLN_02682 6.9e-69
HCIGHHLN_02683 7.1e-35 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HCIGHHLN_02684 1.4e-95 V VanZ like family
HCIGHHLN_02685 9.4e-194 blaA6 V Beta-lactamase
HCIGHHLN_02686 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HCIGHHLN_02687 6.7e-161 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCIGHHLN_02688 5.1e-53 yitW S Pfam:DUF59
HCIGHHLN_02689 5.9e-174 S Aldo keto reductase
HCIGHHLN_02690 1.1e-95 FG HIT domain
HCIGHHLN_02691 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
HCIGHHLN_02692 1.4e-77
HCIGHHLN_02693 1.7e-119 E GDSL-like Lipase/Acylhydrolase family
HCIGHHLN_02694 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
HCIGHHLN_02695 0.0 cadA P P-type ATPase
HCIGHHLN_02697 1.9e-124 yyaQ S YjbR
HCIGHHLN_02698 1.8e-220 S Uncharacterized protein conserved in bacteria (DUF2325)
HCIGHHLN_02699 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HCIGHHLN_02700 1.3e-199 frlB M SIS domain
HCIGHHLN_02701 2.8e-27 3.2.2.10 S Belongs to the LOG family
HCIGHHLN_02702 1.2e-255 nhaC C Na H antiporter NhaC
HCIGHHLN_02703 2.4e-251 cycA E Amino acid permease
HCIGHHLN_02704 1.8e-167 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_02705 7.3e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HCIGHHLN_02706 4.8e-162 azoB GM NmrA-like family
HCIGHHLN_02707 9.2e-66 K Winged helix DNA-binding domain
HCIGHHLN_02708 7e-71 spx4 1.20.4.1 P ArsC family
HCIGHHLN_02709 6.3e-66 yeaO S Protein of unknown function, DUF488
HCIGHHLN_02710 4e-53
HCIGHHLN_02711 4.1e-214 mutY L A G-specific adenine glycosylase
HCIGHHLN_02712 1.9e-62
HCIGHHLN_02713 1.3e-85
HCIGHHLN_02714 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
HCIGHHLN_02715 4.5e-55
HCIGHHLN_02716 2.1e-14
HCIGHHLN_02717 1.1e-115 GM NmrA-like family
HCIGHHLN_02718 1.3e-81 elaA S GNAT family
HCIGHHLN_02719 1.6e-158 EG EamA-like transporter family
HCIGHHLN_02720 1.8e-119 S membrane
HCIGHHLN_02721 1.4e-111 S VIT family
HCIGHHLN_02722 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HCIGHHLN_02723 0.0 copB 3.6.3.4 P P-type ATPase
HCIGHHLN_02724 4.7e-73 copR K Copper transport repressor CopY TcrY
HCIGHHLN_02725 7.4e-40
HCIGHHLN_02726 7.7e-73 S COG NOG18757 non supervised orthologous group
HCIGHHLN_02727 2.5e-248 lmrB EGP Major facilitator Superfamily
HCIGHHLN_02728 3.4e-25
HCIGHHLN_02729 4.2e-49
HCIGHHLN_02730 9.4e-65 ycgX S Protein of unknown function (DUF1398)
HCIGHHLN_02731 1.2e-250 U Belongs to the purine-cytosine permease (2.A.39) family
HCIGHHLN_02732 7.7e-214 mdtG EGP Major facilitator Superfamily
HCIGHHLN_02733 6.8e-181 D Alpha beta
HCIGHHLN_02734 1.2e-77 M1-874 K Domain of unknown function (DUF1836)
HCIGHHLN_02735 1.3e-84 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HCIGHHLN_02736 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HCIGHHLN_02737 2.1e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HCIGHHLN_02738 3.8e-152 ywkB S Membrane transport protein
HCIGHHLN_02739 5.2e-164 yvgN C Aldo keto reductase
HCIGHHLN_02740 5e-131 thrE S Putative threonine/serine exporter
HCIGHHLN_02741 2e-77 S Threonine/Serine exporter, ThrE
HCIGHHLN_02742 2.3e-43 S Protein of unknown function (DUF1093)
HCIGHHLN_02743 1.5e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCIGHHLN_02744 1.3e-90 ymdB S Macro domain protein
HCIGHHLN_02745 1.2e-95 K transcriptional regulator
HCIGHHLN_02746 5.5e-50 yvlA
HCIGHHLN_02747 1e-160 ypuA S Protein of unknown function (DUF1002)
HCIGHHLN_02748 0.0
HCIGHHLN_02749 1.5e-186 S Bacterial protein of unknown function (DUF916)
HCIGHHLN_02750 1.7e-129 S WxL domain surface cell wall-binding
HCIGHHLN_02751 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
HCIGHHLN_02752 1.2e-88 K Winged helix DNA-binding domain
HCIGHHLN_02753 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
HCIGHHLN_02754 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HCIGHHLN_02755 1.8e-27
HCIGHHLN_02756 1.3e-284 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HCIGHHLN_02757 1.5e-75 mltD CBM50 M PFAM NLP P60 protein
HCIGHHLN_02758 1.1e-53
HCIGHHLN_02759 2.1e-61
HCIGHHLN_02761 8.1e-108
HCIGHHLN_02762 2.5e-52 S Uncharacterized protein conserved in bacteria (DUF2316)
HCIGHHLN_02763 2.6e-159 4.1.1.46 S Amidohydrolase
HCIGHHLN_02764 6.7e-99 K transcriptional regulator
HCIGHHLN_02765 1.2e-182 yfeX P Peroxidase
HCIGHHLN_02766 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HCIGHHLN_02767 2.4e-127 ydcF S Gram-negative-bacterium-type cell wall biogenesis
HCIGHHLN_02768 5.6e-183 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
HCIGHHLN_02769 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HCIGHHLN_02770 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_02771 1.5e-55 txlA O Thioredoxin-like domain
HCIGHHLN_02772 2.1e-39 yrkD S Metal-sensitive transcriptional repressor
HCIGHHLN_02773 1.6e-18
HCIGHHLN_02774 6.6e-96 dps P Belongs to the Dps family
HCIGHHLN_02775 1.6e-32 copZ P Heavy-metal-associated domain
HCIGHHLN_02776 1.1e-116 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HCIGHHLN_02777 0.0 pepO 3.4.24.71 O Peptidase family M13
HCIGHHLN_02778 1.9e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCIGHHLN_02779 8.4e-262 nox C NADH oxidase
HCIGHHLN_02780 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HCIGHHLN_02781 6.1e-164 S Cell surface protein
HCIGHHLN_02782 1.7e-117 S WxL domain surface cell wall-binding
HCIGHHLN_02783 2.3e-99 S WxL domain surface cell wall-binding
HCIGHHLN_02784 4.6e-45
HCIGHHLN_02785 1.6e-103 K Bacterial regulatory proteins, tetR family
HCIGHHLN_02786 1.5e-49
HCIGHHLN_02787 1.1e-248 S Putative metallopeptidase domain
HCIGHHLN_02788 2.4e-220 3.1.3.1 S associated with various cellular activities
HCIGHHLN_02789 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HCIGHHLN_02790 0.0 ubiB S ABC1 family
HCIGHHLN_02791 6.9e-251 brnQ U Component of the transport system for branched-chain amino acids
HCIGHHLN_02792 0.0 lacS G Transporter
HCIGHHLN_02793 0.0 lacA 3.2.1.23 G -beta-galactosidase
HCIGHHLN_02794 1.6e-188 lacR K Transcriptional regulator
HCIGHHLN_02795 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCIGHHLN_02796 1.6e-230 mdtH P Sugar (and other) transporter
HCIGHHLN_02797 3e-303 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
HCIGHHLN_02798 8.6e-232 EGP Major facilitator Superfamily
HCIGHHLN_02799 3.7e-182 rhaR K helix_turn_helix, arabinose operon control protein
HCIGHHLN_02800 1.3e-110 fic D Fic/DOC family
HCIGHHLN_02801 1.6e-76 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_02802 2e-183 galR K Transcriptional regulator
HCIGHHLN_02803 1.3e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HCIGHHLN_02804 1.2e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCIGHHLN_02805 9.3e-225 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HCIGHHLN_02806 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HCIGHHLN_02807 8.3e-187 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HCIGHHLN_02808 0.0 rafA 3.2.1.22 G alpha-galactosidase
HCIGHHLN_02809 0.0 lacS G Transporter
HCIGHHLN_02810 4.1e-200 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HCIGHHLN_02811 1.1e-173 galR K Transcriptional regulator
HCIGHHLN_02812 2.6e-194 C Aldo keto reductase family protein
HCIGHHLN_02813 2.4e-65 S pyridoxamine 5-phosphate
HCIGHHLN_02814 0.0 1.3.5.4 C FAD binding domain
HCIGHHLN_02815 8.2e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HCIGHHLN_02816 1.9e-130 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HCIGHHLN_02817 1.2e-214 ydiM G Transporter
HCIGHHLN_02818 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HCIGHHLN_02819 3.4e-163 K Transcriptional regulator, LysR family
HCIGHHLN_02820 6.7e-210 ydiN G Major Facilitator Superfamily
HCIGHHLN_02821 7.6e-64
HCIGHHLN_02822 1.8e-155 estA S Putative esterase
HCIGHHLN_02823 1.2e-134 K UTRA domain
HCIGHHLN_02824 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_02825 8.8e-165 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HCIGHHLN_02826 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HCIGHHLN_02827 1.1e-211 S Bacterial protein of unknown function (DUF871)
HCIGHHLN_02828 3.5e-290 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02829 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_02830 1.3e-154 licT K CAT RNA binding domain
HCIGHHLN_02831 4.9e-292 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02832 9.4e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02833 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_02834 3.8e-159 licT K CAT RNA binding domain
HCIGHHLN_02835 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HCIGHHLN_02836 1.4e-173 K Transcriptional regulator, LacI family
HCIGHHLN_02837 3e-270 G Major Facilitator
HCIGHHLN_02838 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HCIGHHLN_02840 9.9e-188 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCIGHHLN_02841 3e-145 yxeH S hydrolase
HCIGHHLN_02842 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HCIGHHLN_02843 7e-113 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCIGHHLN_02844 4.1e-127 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
HCIGHHLN_02845 6.6e-172 G Phosphotransferase System
HCIGHHLN_02846 8.6e-48 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_02847 9.1e-75 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_02849 3.5e-237 manR K PRD domain
HCIGHHLN_02850 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HCIGHHLN_02851 1.1e-231 gatC G PTS system sugar-specific permease component
HCIGHHLN_02852 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_02853 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_02854 5.2e-123 K DeoR C terminal sensor domain
HCIGHHLN_02855 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HCIGHHLN_02856 2.6e-70 yueI S Protein of unknown function (DUF1694)
HCIGHHLN_02857 9.6e-103 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HCIGHHLN_02858 7.8e-266 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCIGHHLN_02859 6.6e-136 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HCIGHHLN_02860 2.7e-307 araB 2.7.1.12, 2.7.1.16, 2.7.1.5 G carbohydrate kinase FGGY
HCIGHHLN_02861 1.6e-255 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HCIGHHLN_02862 3.1e-206 araR K Transcriptional regulator
HCIGHHLN_02863 3e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HCIGHHLN_02864 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HCIGHHLN_02865 4.2e-70 S Pyrimidine dimer DNA glycosylase
HCIGHHLN_02866 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
HCIGHHLN_02867 3.6e-11
HCIGHHLN_02868 9e-13 ytgB S Transglycosylase associated protein
HCIGHHLN_02869 1.9e-291 katA 1.11.1.6 C Belongs to the catalase family
HCIGHHLN_02870 4.9e-78 yneH 1.20.4.1 K ArsC family
HCIGHHLN_02871 5.7e-135 K LytTr DNA-binding domain
HCIGHHLN_02872 3.2e-223 2.7.13.3 T GHKL domain
HCIGHHLN_02873 5.7e-16
HCIGHHLN_02874 7.7e-98 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
HCIGHHLN_02875 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
HCIGHHLN_02877 6.1e-202 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HCIGHHLN_02878 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIGHHLN_02879 8.7e-72 K Transcriptional regulator
HCIGHHLN_02880 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HCIGHHLN_02881 9.3e-71 yueI S Protein of unknown function (DUF1694)
HCIGHHLN_02882 1e-125 S Membrane
HCIGHHLN_02883 4.6e-165 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
HCIGHHLN_02884 3.8e-256 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
HCIGHHLN_02885 1.4e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HCIGHHLN_02886 1.8e-286 rhaB 2.7.1.12, 2.7.1.16, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HCIGHHLN_02887 1.6e-244 iolF EGP Major facilitator Superfamily
HCIGHHLN_02888 3.8e-179 rhaR K helix_turn_helix, arabinose operon control protein
HCIGHHLN_02889 2.1e-140 K DeoR C terminal sensor domain
HCIGHHLN_02890 6.4e-34 traW S Type-F conjugative transfer system protein TraW
HCIGHHLN_02895 5.1e-08
HCIGHHLN_02901 1.4e-90 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
HCIGHHLN_02902 4e-182 P secondary active sulfate transmembrane transporter activity
HCIGHHLN_02903 2.6e-94
HCIGHHLN_02904 2e-94 K Acetyltransferase (GNAT) domain
HCIGHHLN_02905 1.1e-155 T Calcineurin-like phosphoesterase superfamily domain
HCIGHHLN_02907 5.2e-232 mntH P H( )-stimulated, divalent metal cation uptake system
HCIGHHLN_02908 7.6e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HCIGHHLN_02909 1.7e-254 mmuP E amino acid
HCIGHHLN_02910 1.3e-168 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HCIGHHLN_02911 1.9e-294 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIGHHLN_02912 1.6e-121
HCIGHHLN_02913 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCIGHHLN_02914 9.3e-278 bmr3 EGP Major facilitator Superfamily
HCIGHHLN_02915 1.8e-144 N Cell shape-determining protein MreB
HCIGHHLN_02918 0.0 S Pfam Methyltransferase
HCIGHHLN_02919 2e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIGHHLN_02920 1.8e-297 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HCIGHHLN_02921 4.2e-29
HCIGHHLN_02922 4.5e-94 ytqB 2.1.1.176 J Putative rRNA methylase
HCIGHHLN_02923 2.3e-124 3.6.1.27 I Acid phosphatase homologues
HCIGHHLN_02924 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCIGHHLN_02925 8.7e-301 ytgP S Polysaccharide biosynthesis protein
HCIGHHLN_02926 6.7e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCIGHHLN_02927 6.4e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCIGHHLN_02928 1.7e-273 pepV 3.5.1.18 E dipeptidase PepV
HCIGHHLN_02929 4.1e-84 uspA T Belongs to the universal stress protein A family
HCIGHHLN_02930 1.8e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
HCIGHHLN_02931 6.8e-173 ugpA U Binding-protein-dependent transport system inner membrane component
HCIGHHLN_02932 1.1e-150 ugpE G ABC transporter permease
HCIGHHLN_02933 5.5e-261 ugpB G Bacterial extracellular solute-binding protein
HCIGHHLN_02934 3.8e-125 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HCIGHHLN_02935 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
HCIGHHLN_02936 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCIGHHLN_02937 1.5e-178 XK27_06930 V domain protein
HCIGHHLN_02939 1.1e-114 V Transport permease protein
HCIGHHLN_02940 2.3e-156 V ABC transporter
HCIGHHLN_02941 4e-176 K LytTr DNA-binding domain
HCIGHHLN_02943 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCIGHHLN_02944 7.2e-38 K helix_turn_helix, mercury resistance
HCIGHHLN_02945 3.5e-117 GM NAD(P)H-binding
HCIGHHLN_02946 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HCIGHHLN_02947 2.9e-148 S Sucrose-6F-phosphate phosphohydrolase
HCIGHHLN_02948 1.7e-108
HCIGHHLN_02949 2.2e-224 pltK 2.7.13.3 T GHKL domain
HCIGHHLN_02950 1.6e-137 pltR K LytTr DNA-binding domain
HCIGHHLN_02951 4.5e-55
HCIGHHLN_02952 2.5e-59
HCIGHHLN_02953 1.9e-113 S CAAX protease self-immunity
HCIGHHLN_02954 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
HCIGHHLN_02955 1.9e-89
HCIGHHLN_02956 2.5e-46
HCIGHHLN_02957 0.0 uvrA2 L ABC transporter
HCIGHHLN_02960 5.9e-52
HCIGHHLN_02961 3.5e-10
HCIGHHLN_02962 2.1e-180
HCIGHHLN_02963 1.9e-89 gtcA S Teichoic acid glycosylation protein
HCIGHHLN_02964 3.6e-58 S Protein of unknown function (DUF1516)
HCIGHHLN_02965 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HCIGHHLN_02966 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCIGHHLN_02967 6.1e-307 S Protein conserved in bacteria
HCIGHHLN_02968 4.8e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
HCIGHHLN_02969 2.5e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
HCIGHHLN_02970 1.5e-175 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
HCIGHHLN_02971 3.9e-304 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HCIGHHLN_02972 0.0 yfbS P Sodium:sulfate symporter transmembrane region
HCIGHHLN_02973 6.2e-244 dinF V MatE
HCIGHHLN_02974 1.9e-31
HCIGHHLN_02977 7.7e-79 elaA S Acetyltransferase (GNAT) domain
HCIGHHLN_02978 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCIGHHLN_02979 1.4e-81
HCIGHHLN_02980 0.0 yhcA V MacB-like periplasmic core domain
HCIGHHLN_02981 7.6e-107
HCIGHHLN_02982 0.0 K PRD domain
HCIGHHLN_02983 5.9e-61 S Domain of unknown function (DUF3284)
HCIGHHLN_02984 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
HCIGHHLN_02985 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_02986 1.6e-244 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HCIGHHLN_02987 1.5e-288 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HCIGHHLN_02988 1.1e-204 EGP Major facilitator Superfamily
HCIGHHLN_02989 2e-114 M ErfK YbiS YcfS YnhG
HCIGHHLN_02990 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HCIGHHLN_02991 8.4e-284 ydfD K Alanine-glyoxylate amino-transferase
HCIGHHLN_02992 4e-102 argO S LysE type translocator
HCIGHHLN_02993 1.5e-211 arcT 2.6.1.1 E Aminotransferase
HCIGHHLN_02994 4.4e-77 argR K Regulates arginine biosynthesis genes
HCIGHHLN_02995 2.9e-12
HCIGHHLN_02996 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HCIGHHLN_02997 1e-54 yheA S Belongs to the UPF0342 family
HCIGHHLN_02998 6.3e-232 yhaO L Ser Thr phosphatase family protein
HCIGHHLN_02999 0.0 L AAA domain
HCIGHHLN_03000 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCIGHHLN_03001 2.1e-216
HCIGHHLN_03002 2.8e-182 3.4.21.102 M Peptidase family S41
HCIGHHLN_03003 1.2e-177 K LysR substrate binding domain
HCIGHHLN_03004 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
HCIGHHLN_03005 0.0 1.3.5.4 C FAD binding domain
HCIGHHLN_03006 1.7e-99
HCIGHHLN_03007 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HCIGHHLN_03008 8.4e-60 M domain protein
HCIGHHLN_03009 1.2e-22 M domain protein
HCIGHHLN_03010 1.4e-72 M domain protein
HCIGHHLN_03011 5.7e-23 M domain protein
HCIGHHLN_03014 8.1e-84 3.2.1.17, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCIGHHLN_03015 1.6e-70 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HCIGHHLN_03016 1.2e-104 M ErfK YbiS YcfS YnhG
HCIGHHLN_03017 2.3e-101 akr5f 1.1.1.346 S reductase
HCIGHHLN_03018 4.6e-35 S aldo-keto reductase (NADP) activity
HCIGHHLN_03019 3.3e-109 GM NAD(P)H-binding
HCIGHHLN_03020 2.2e-78 3.5.4.1 GM SnoaL-like domain
HCIGHHLN_03021 6.5e-260 qacA EGP Fungal trichothecene efflux pump (TRI12)
HCIGHHLN_03022 9.2e-65 S Domain of unknown function (DUF4440)
HCIGHHLN_03023 2.4e-104 K Bacterial regulatory proteins, tetR family
HCIGHHLN_03025 1.5e-32 L transposase activity
HCIGHHLN_03027 8.8e-40
HCIGHHLN_03028 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCIGHHLN_03029 1.9e-171 K AI-2E family transporter
HCIGHHLN_03030 2.9e-210 xylR GK ROK family
HCIGHHLN_03031 2.1e-79
HCIGHHLN_03032 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HCIGHHLN_03033 3.9e-162
HCIGHHLN_03034 3.2e-200 KLT Protein tyrosine kinase
HCIGHHLN_03035 2.9e-23 S Protein of unknown function (DUF4064)
HCIGHHLN_03036 6e-97 S Domain of unknown function (DUF4352)
HCIGHHLN_03037 3.9e-75 S Psort location Cytoplasmic, score
HCIGHHLN_03038 4.8e-55
HCIGHHLN_03039 3.6e-110 S membrane transporter protein
HCIGHHLN_03040 2.3e-54 azlD S branched-chain amino acid
HCIGHHLN_03041 5.1e-131 azlC E branched-chain amino acid
HCIGHHLN_03042 1.3e-90 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HCIGHHLN_03043 4.9e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HCIGHHLN_03044 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
HCIGHHLN_03045 3.2e-124 K response regulator
HCIGHHLN_03046 5.5e-124 yoaK S Protein of unknown function (DUF1275)
HCIGHHLN_03047 2.9e-160 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HCIGHHLN_03048 2.3e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCIGHHLN_03049 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
HCIGHHLN_03050 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCIGHHLN_03051 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
HCIGHHLN_03052 4.8e-157 spo0J K Belongs to the ParB family
HCIGHHLN_03053 1.8e-136 soj D Sporulation initiation inhibitor
HCIGHHLN_03054 2.7e-149 noc K Belongs to the ParB family
HCIGHHLN_03055 1.7e-128 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HCIGHHLN_03056 4.1e-226 nupG F Nucleoside
HCIGHHLN_03057 0.0 S Bacterial membrane protein YfhO
HCIGHHLN_03058 4.3e-147 S Alpha/beta hydrolase of unknown function (DUF915)
HCIGHHLN_03059 2.1e-168 K LysR substrate binding domain
HCIGHHLN_03060 1.9e-236 EK Aminotransferase, class I
HCIGHHLN_03061 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCIGHHLN_03062 8.1e-123 tcyB E ABC transporter
HCIGHHLN_03063 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HCIGHHLN_03064 1.3e-129 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HCIGHHLN_03065 3.8e-78 KT response to antibiotic
HCIGHHLN_03066 1.5e-52 K Transcriptional regulator
HCIGHHLN_03067 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
HCIGHHLN_03068 1.7e-128 S Putative adhesin
HCIGHHLN_03069 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_03070 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HCIGHHLN_03071 3.7e-182 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
HCIGHHLN_03072 2.2e-204 S DUF218 domain
HCIGHHLN_03073 2e-127 ybbM S Uncharacterised protein family (UPF0014)
HCIGHHLN_03074 9.4e-118 ybbL S ABC transporter, ATP-binding protein
HCIGHHLN_03075 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCIGHHLN_03076 9.4e-77
HCIGHHLN_03077 3.4e-152 qorB 1.6.5.2 GM NmrA-like family
HCIGHHLN_03078 1.4e-147 cof S haloacid dehalogenase-like hydrolase
HCIGHHLN_03079 1.1e-92 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HCIGHHLN_03080 1.5e-307 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
HCIGHHLN_03081 2.8e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
HCIGHHLN_03082 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
HCIGHHLN_03083 2.9e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HCIGHHLN_03084 2.2e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HCIGHHLN_03085 2e-77 merR K MerR family regulatory protein
HCIGHHLN_03086 1.4e-156 1.6.5.2 GM NmrA-like family
HCIGHHLN_03087 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
HCIGHHLN_03088 4.3e-126 magIII L Base excision DNA repair protein, HhH-GPD family
HCIGHHLN_03089 1.4e-08
HCIGHHLN_03090 2e-100 S NADPH-dependent FMN reductase
HCIGHHLN_03091 3e-237 S module of peptide synthetase
HCIGHHLN_03092 9.3e-104
HCIGHHLN_03093 9.8e-88 perR P Belongs to the Fur family
HCIGHHLN_03094 2.1e-58 S Enterocin A Immunity
HCIGHHLN_03095 5.4e-36 S Phospholipase_D-nuclease N-terminal
HCIGHHLN_03096 1.8e-169 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HCIGHHLN_03097 3.8e-104 J Acetyltransferase (GNAT) domain
HCIGHHLN_03098 4.3e-63 lrgA S LrgA family
HCIGHHLN_03099 7.3e-127 lrgB M LrgB-like family
HCIGHHLN_03100 2.5e-145 DegV S EDD domain protein, DegV family
HCIGHHLN_03101 4.1e-25
HCIGHHLN_03102 7.7e-118 yugP S Putative neutral zinc metallopeptidase
HCIGHHLN_03103 3.2e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
HCIGHHLN_03104 2.8e-165 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
HCIGHHLN_03105 1.7e-184 D Alpha beta
HCIGHHLN_03106 7.1e-198 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HCIGHHLN_03107 8.1e-257 gor 1.8.1.7 C Glutathione reductase
HCIGHHLN_03108 3.4e-55 S Enterocin A Immunity
HCIGHHLN_03109 7.4e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HCIGHHLN_03110 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCIGHHLN_03111 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HCIGHHLN_03112 4.4e-146 ptp2 3.1.3.48 T Tyrosine phosphatase family
HCIGHHLN_03113 1.4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HCIGHHLN_03115 7.3e-83
HCIGHHLN_03116 6.6e-257 yhdG E C-terminus of AA_permease
HCIGHHLN_03118 0.0 kup P Transport of potassium into the cell
HCIGHHLN_03119 5.1e-165 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCIGHHLN_03120 3.1e-179 K AI-2E family transporter
HCIGHHLN_03121 7.6e-216 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HCIGHHLN_03122 4.4e-59 qacC P Small Multidrug Resistance protein
HCIGHHLN_03123 1.1e-44 qacH U Small Multidrug Resistance protein
HCIGHHLN_03124 3e-116 hly S protein, hemolysin III
HCIGHHLN_03125 1.5e-53 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
HCIGHHLN_03126 2.7e-160 czcD P cation diffusion facilitator family transporter
HCIGHHLN_03127 5.1e-102 K Helix-turn-helix XRE-family like proteins
HCIGHHLN_03129 2.1e-21
HCIGHHLN_03130 6.5e-96 tag 3.2.2.20 L glycosylase
HCIGHHLN_03131 3.4e-211 folP 2.5.1.15 H dihydropteroate synthase
HCIGHHLN_03132 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
HCIGHHLN_03133 4.1e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HCIGHHLN_03134 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
HCIGHHLN_03135 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
HCIGHHLN_03136 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCIGHHLN_03137 4.7e-83 cvpA S Colicin V production protein
HCIGHHLN_03138 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
HCIGHHLN_03139 1.3e-249 EGP Major facilitator Superfamily
HCIGHHLN_03141 1.2e-39

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)