ORF_ID e_value Gene_name EC_number CAZy COGs Description
HKKKDAFM_00001 1.6e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HKKKDAFM_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HKKKDAFM_00003 2.4e-33 yaaA S S4 domain
HKKKDAFM_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HKKKDAFM_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
HKKKDAFM_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKKKDAFM_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HKKKDAFM_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00011 1e-181 yaaC S YaaC-like Protein
HKKKDAFM_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HKKKDAFM_00013 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HKKKDAFM_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HKKKDAFM_00015 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HKKKDAFM_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HKKKDAFM_00017 1.3e-09
HKKKDAFM_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HKKKDAFM_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HKKKDAFM_00020 4.5e-212 yaaH M Glycoside Hydrolase Family
HKKKDAFM_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
HKKKDAFM_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HKKKDAFM_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKKKDAFM_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HKKKDAFM_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HKKKDAFM_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HKKKDAFM_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HKKKDAFM_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
HKKKDAFM_00032 2.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HKKKDAFM_00033 1.2e-200 yaaN P Belongs to the TelA family
HKKKDAFM_00034 8.7e-273 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HKKKDAFM_00035 2e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HKKKDAFM_00036 2.2e-54 yaaQ S protein conserved in bacteria
HKKKDAFM_00037 1.5e-71 yaaR S protein conserved in bacteria
HKKKDAFM_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
HKKKDAFM_00039 6.1e-146 yaaT S stage 0 sporulation protein
HKKKDAFM_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
HKKKDAFM_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HKKKDAFM_00042 2.8e-48 yazA L endonuclease containing a URI domain
HKKKDAFM_00043 1e-151 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HKKKDAFM_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HKKKDAFM_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HKKKDAFM_00046 1.2e-143 tatD L hydrolase, TatD
HKKKDAFM_00047 2e-167 rpfB GH23 T protein conserved in bacteria
HKKKDAFM_00048 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HKKKDAFM_00049 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HKKKDAFM_00050 1.6e-136 yabG S peptidase
HKKKDAFM_00051 7.8e-39 veg S protein conserved in bacteria
HKKKDAFM_00052 8.3e-27 sspF S DNA topological change
HKKKDAFM_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HKKKDAFM_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HKKKDAFM_00055 5.6e-62 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HKKKDAFM_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HKKKDAFM_00057 2.5e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HKKKDAFM_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HKKKDAFM_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HKKKDAFM_00060 2.3e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HKKKDAFM_00061 2.4e-39 yabK S Peptide ABC transporter permease
HKKKDAFM_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HKKKDAFM_00063 1.5e-92 spoVT K stage V sporulation protein
HKKKDAFM_00064 2.1e-283 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_00065 3e-244 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HKKKDAFM_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HKKKDAFM_00067 1.5e-49 yabP S Sporulation protein YabP
HKKKDAFM_00068 2.5e-107 yabQ S spore cortex biosynthesis protein
HKKKDAFM_00069 1.1e-44 divIC D Septum formation initiator
HKKKDAFM_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HKKKDAFM_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HKKKDAFM_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HKKKDAFM_00075 1.4e-184 KLT serine threonine protein kinase
HKKKDAFM_00076 4.7e-271 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HKKKDAFM_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HKKKDAFM_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HKKKDAFM_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HKKKDAFM_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HKKKDAFM_00081 6.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HKKKDAFM_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKKKDAFM_00083 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKKKDAFM_00084 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HKKKDAFM_00085 3.3e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HKKKDAFM_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HKKKDAFM_00087 7.7e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HKKKDAFM_00088 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HKKKDAFM_00089 4.1e-30 yazB K transcriptional
HKKKDAFM_00090 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKKKDAFM_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HKKKDAFM_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00097 2e-08
HKKKDAFM_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00103 2.9e-76 ctsR K Belongs to the CtsR family
HKKKDAFM_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HKKKDAFM_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HKKKDAFM_00106 0.0 clpC O Belongs to the ClpA ClpB family
HKKKDAFM_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HKKKDAFM_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HKKKDAFM_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HKKKDAFM_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HKKKDAFM_00111 1.2e-85 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HKKKDAFM_00112 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HKKKDAFM_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HKKKDAFM_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKKKDAFM_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HKKKDAFM_00116 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKKKDAFM_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HKKKDAFM_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
HKKKDAFM_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HKKKDAFM_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
HKKKDAFM_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HKKKDAFM_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HKKKDAFM_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HKKKDAFM_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HKKKDAFM_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HKKKDAFM_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKKDAFM_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKKDAFM_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HKKKDAFM_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HKKKDAFM_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HKKKDAFM_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HKKKDAFM_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HKKKDAFM_00133 1.7e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HKKKDAFM_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HKKKDAFM_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HKKKDAFM_00136 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
HKKKDAFM_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HKKKDAFM_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HKKKDAFM_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HKKKDAFM_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HKKKDAFM_00141 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HKKKDAFM_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HKKKDAFM_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HKKKDAFM_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HKKKDAFM_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HKKKDAFM_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HKKKDAFM_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HKKKDAFM_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKKKDAFM_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HKKKDAFM_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HKKKDAFM_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HKKKDAFM_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HKKKDAFM_00153 1.9e-23 rpmD J Ribosomal protein L30
HKKKDAFM_00154 1.8e-72 rplO J binds to the 23S rRNA
HKKKDAFM_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HKKKDAFM_00156 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HKKKDAFM_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HKKKDAFM_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HKKKDAFM_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HKKKDAFM_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HKKKDAFM_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HKKKDAFM_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HKKKDAFM_00163 3.6e-58 rplQ J Ribosomal protein L17
HKKKDAFM_00164 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKKDAFM_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKKDAFM_00166 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HKKKDAFM_00167 8.2e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HKKKDAFM_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HKKKDAFM_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HKKKDAFM_00170 9e-144 ybaJ Q Methyltransferase domain
HKKKDAFM_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HKKKDAFM_00172 2.5e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKKDAFM_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HKKKDAFM_00174 1.2e-84 gerD
HKKKDAFM_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HKKKDAFM_00176 7.9e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HKKKDAFM_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00180 2e-08
HKKKDAFM_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKKKDAFM_00188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HKKKDAFM_00189 2.2e-142 ybbA S Putative esterase
HKKKDAFM_00190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00192 1.4e-165 feuA P Iron-uptake system-binding protein
HKKKDAFM_00193 5e-306 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HKKKDAFM_00194 4.1e-239 ybbC 3.2.1.52 S protein conserved in bacteria
HKKKDAFM_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HKKKDAFM_00196 4.2e-225 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HKKKDAFM_00197 1.9e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_00198 2.1e-149 ybbH K transcriptional
HKKKDAFM_00199 1.4e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HKKKDAFM_00200 1.9e-86 ybbJ J acetyltransferase
HKKKDAFM_00201 1.5e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HKKKDAFM_00207 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_00208 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HKKKDAFM_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKKKDAFM_00210 1.5e-224 ybbR S protein conserved in bacteria
HKKKDAFM_00211 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HKKKDAFM_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HKKKDAFM_00213 1.5e-174 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKKKDAFM_00214 1.7e-119 adaA 3.2.2.21 K Transcriptional regulator
HKKKDAFM_00215 3.7e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKKKDAFM_00216 1.1e-270 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKKKDAFM_00217 0.0 ybcC S Belongs to the UPF0753 family
HKKKDAFM_00218 4.7e-91 can 4.2.1.1 P carbonic anhydrase
HKKKDAFM_00220 5.6e-46
HKKKDAFM_00221 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HKKKDAFM_00222 5.1e-50 ybzH K Helix-turn-helix domain
HKKKDAFM_00223 1.2e-200 ybcL EGP Major facilitator Superfamily
HKKKDAFM_00224 2.5e-56
HKKKDAFM_00225 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKKKDAFM_00226 4.2e-121 T Transcriptional regulatory protein, C terminal
HKKKDAFM_00227 5.9e-172 T His Kinase A (phospho-acceptor) domain
HKKKDAFM_00229 5.1e-139 KLT Protein tyrosine kinase
HKKKDAFM_00230 3.8e-151 ybdN
HKKKDAFM_00231 3.6e-216 ybdO S Domain of unknown function (DUF4885)
HKKKDAFM_00232 2.6e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_00233 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HKKKDAFM_00234 4.9e-30 ybxH S Family of unknown function (DUF5370)
HKKKDAFM_00235 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
HKKKDAFM_00236 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HKKKDAFM_00237 4.9e-41 ybyB
HKKKDAFM_00238 8.8e-290 ybeC E amino acid
HKKKDAFM_00239 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKKDAFM_00240 7.3e-258 glpT G -transporter
HKKKDAFM_00241 2.9e-35 S Protein of unknown function (DUF2651)
HKKKDAFM_00242 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HKKKDAFM_00243 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HKKKDAFM_00245 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HKKKDAFM_00246 3.7e-160 ybfH EG EamA-like transporter family
HKKKDAFM_00247 5.2e-145 msmR K AraC-like ligand binding domain
HKKKDAFM_00248 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HKKKDAFM_00249 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HKKKDAFM_00251 1e-167 S Alpha/beta hydrolase family
HKKKDAFM_00252 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKKKDAFM_00253 2.7e-85 ybfM S SNARE associated Golgi protein
HKKKDAFM_00254 6.9e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HKKKDAFM_00255 2e-45 ybfN
HKKKDAFM_00256 6.4e-09 S Erythromycin esterase
HKKKDAFM_00257 3.3e-191 yceA S Belongs to the UPF0176 family
HKKKDAFM_00258 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKKDAFM_00259 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_00260 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKKKDAFM_00261 4.9e-128 K UTRA
HKKKDAFM_00263 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKKKDAFM_00264 1.4e-259 mmuP E amino acid
HKKKDAFM_00265 1e-181 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HKKKDAFM_00266 2.8e-255 agcS E Sodium alanine symporter
HKKKDAFM_00267 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
HKKKDAFM_00268 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HKKKDAFM_00269 2.6e-169 glnL T Regulator
HKKKDAFM_00270 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HKKKDAFM_00271 3.2e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKKDAFM_00272 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HKKKDAFM_00273 1.2e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKKKDAFM_00274 2.1e-123 ycbG K FCD
HKKKDAFM_00275 1.1e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
HKKKDAFM_00276 8.6e-167 ycbJ S Macrolide 2'-phosphotransferase
HKKKDAFM_00277 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HKKKDAFM_00278 5.4e-167 eamA1 EG spore germination
HKKKDAFM_00279 8.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_00280 4.2e-167 T PhoQ Sensor
HKKKDAFM_00281 3.5e-166 ycbN V ABC transporter, ATP-binding protein
HKKKDAFM_00282 1.8e-114 S ABC-2 family transporter protein
HKKKDAFM_00283 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HKKKDAFM_00284 2.8e-78 sleB 3.5.1.28 M Cell wall
HKKKDAFM_00285 3.6e-134 ycbR T vWA found in TerF C terminus
HKKKDAFM_00286 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HKKKDAFM_00287 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKKKDAFM_00288 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKKKDAFM_00289 6.9e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HKKKDAFM_00290 2.9e-199 ycbU E Selenocysteine lyase
HKKKDAFM_00291 3e-225 lmrB EGP the major facilitator superfamily
HKKKDAFM_00292 4.8e-102 yxaF K Transcriptional regulator
HKKKDAFM_00293 5.3e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HKKKDAFM_00294 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKKKDAFM_00295 4.9e-58 S RDD family
HKKKDAFM_00296 3.6e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
HKKKDAFM_00297 1.2e-156 2.7.13.3 T GHKL domain
HKKKDAFM_00298 1.2e-126 lytR_2 T LytTr DNA-binding domain
HKKKDAFM_00299 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HKKKDAFM_00300 2.7e-200 natB CP ABC-2 family transporter protein
HKKKDAFM_00301 1.7e-22 yccK C Aldo keto reductase
HKKKDAFM_00302 1e-142 yccK C Aldo keto reductase
HKKKDAFM_00303 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HKKKDAFM_00304 5.2e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_00305 3.1e-257 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_00306 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
HKKKDAFM_00307 6.1e-173 S response regulator aspartate phosphatase
HKKKDAFM_00308 1e-139 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_00309 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HKKKDAFM_00310 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HKKKDAFM_00311 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKKKDAFM_00312 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKKKDAFM_00313 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_00314 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HKKKDAFM_00315 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HKKKDAFM_00316 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HKKKDAFM_00317 6.3e-137 terC P Protein of unknown function (DUF475)
HKKKDAFM_00318 0.0 yceG S Putative component of 'biosynthetic module'
HKKKDAFM_00319 2e-192 yceH P Belongs to the TelA family
HKKKDAFM_00320 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HKKKDAFM_00321 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HKKKDAFM_00322 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HKKKDAFM_00323 5.1e-229 proV 3.6.3.32 E glycine betaine
HKKKDAFM_00324 1.3e-127 opuAB P glycine betaine
HKKKDAFM_00325 1.5e-163 opuAC E glycine betaine
HKKKDAFM_00326 1.1e-217 amhX S amidohydrolase
HKKKDAFM_00327 8.7e-257 ycgA S Membrane
HKKKDAFM_00328 4.1e-81 ycgB
HKKKDAFM_00329 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HKKKDAFM_00330 1.6e-182 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HKKKDAFM_00331 3.3e-289 lctP C L-lactate permease
HKKKDAFM_00332 3.9e-263 mdr EGP Major facilitator Superfamily
HKKKDAFM_00333 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_00334 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HKKKDAFM_00335 1.3e-150 yqcI S YqcI/YcgG family
HKKKDAFM_00336 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_00337 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HKKKDAFM_00338 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HKKKDAFM_00339 2.1e-108 tmrB S AAA domain
HKKKDAFM_00341 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HKKKDAFM_00342 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HKKKDAFM_00343 5.1e-176 oxyR3 K LysR substrate binding domain
HKKKDAFM_00344 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HKKKDAFM_00345 2.9e-145 ycgL S Predicted nucleotidyltransferase
HKKKDAFM_00346 5.1e-170 ycgM E Proline dehydrogenase
HKKKDAFM_00347 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKKKDAFM_00348 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKKDAFM_00349 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HKKKDAFM_00350 2.2e-146 ycgQ S membrane
HKKKDAFM_00351 1.2e-139 ycgR S permeases
HKKKDAFM_00352 7.2e-158 I alpha/beta hydrolase fold
HKKKDAFM_00353 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HKKKDAFM_00354 1.9e-280 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKKKDAFM_00355 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HKKKDAFM_00356 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HKKKDAFM_00357 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKKDAFM_00358 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HKKKDAFM_00359 1.4e-220 nasA P COG2223 Nitrate nitrite transporter
HKKKDAFM_00360 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HKKKDAFM_00361 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HKKKDAFM_00362 4.6e-227 yciC S GTPases (G3E family)
HKKKDAFM_00363 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HKKKDAFM_00364 9.9e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HKKKDAFM_00365 3.6e-47 yckC S membrane
HKKKDAFM_00366 7.8e-52 yckD S Protein of unknown function (DUF2680)
HKKKDAFM_00367 5.7e-39 K MarR family
HKKKDAFM_00368 9.3e-24
HKKKDAFM_00369 6e-121 S AAA domain
HKKKDAFM_00370 7.5e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKKDAFM_00371 6.5e-69 nin S Competence protein J (ComJ)
HKKKDAFM_00372 3e-70 nucA M Deoxyribonuclease NucA/NucB
HKKKDAFM_00373 1.5e-186 tlpC 2.7.13.3 NT chemotaxis protein
HKKKDAFM_00374 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HKKKDAFM_00375 3.6e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HKKKDAFM_00376 1.3e-63 hxlR K transcriptional
HKKKDAFM_00377 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_00378 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_00379 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HKKKDAFM_00380 6.4e-139 srfAD Q thioesterase
HKKKDAFM_00381 6.1e-227 EGP Major Facilitator Superfamily
HKKKDAFM_00382 3.5e-89 S YcxB-like protein
HKKKDAFM_00383 7.4e-164 ycxC EG EamA-like transporter family
HKKKDAFM_00384 4.4e-255 ycxD K GntR family transcriptional regulator
HKKKDAFM_00385 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HKKKDAFM_00386 4.4e-115 yczE S membrane
HKKKDAFM_00387 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKKDAFM_00388 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HKKKDAFM_00389 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HKKKDAFM_00390 4.9e-162 bsdA K LysR substrate binding domain
HKKKDAFM_00391 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HKKKDAFM_00392 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HKKKDAFM_00393 4e-39 bsdD 4.1.1.61 S response to toxic substance
HKKKDAFM_00394 2.3e-81 yclD
HKKKDAFM_00395 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
HKKKDAFM_00396 7.3e-267 dtpT E amino acid peptide transporter
HKKKDAFM_00397 5.9e-292 yclG M Pectate lyase superfamily protein
HKKKDAFM_00399 3.5e-278 gerKA EG Spore germination protein
HKKKDAFM_00400 1.3e-232 gerKC S spore germination
HKKKDAFM_00401 1.7e-199 gerKB F Spore germination protein
HKKKDAFM_00402 1.9e-121 yclH P ABC transporter
HKKKDAFM_00403 4e-201 yclI V ABC transporter (permease) YclI
HKKKDAFM_00404 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_00405 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HKKKDAFM_00406 2e-70 S aspartate phosphatase
HKKKDAFM_00410 5.7e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
HKKKDAFM_00411 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00412 1.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00413 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HKKKDAFM_00414 1.4e-170 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HKKKDAFM_00415 1.4e-251 ycnB EGP Major facilitator Superfamily
HKKKDAFM_00416 7.9e-152 ycnC K Transcriptional regulator
HKKKDAFM_00417 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKKKDAFM_00418 1.6e-45 ycnE S Monooxygenase
HKKKDAFM_00419 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HKKKDAFM_00420 5.6e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_00421 2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKKDAFM_00422 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKKDAFM_00423 1.8e-148 glcU U Glucose uptake
HKKKDAFM_00424 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_00425 2.9e-100 ycnI S protein conserved in bacteria
HKKKDAFM_00426 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HKKKDAFM_00427 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HKKKDAFM_00428 3.4e-53
HKKKDAFM_00429 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HKKKDAFM_00430 7.5e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HKKKDAFM_00431 9e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HKKKDAFM_00432 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HKKKDAFM_00433 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKKDAFM_00434 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKKDAFM_00435 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HKKKDAFM_00436 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HKKKDAFM_00438 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HKKKDAFM_00439 8e-140 ycsF S Belongs to the UPF0271 (lamB) family
HKKKDAFM_00440 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HKKKDAFM_00441 4.8e-148 ycsI S Belongs to the D-glutamate cyclase family
HKKKDAFM_00442 9.4e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HKKKDAFM_00443 1.1e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HKKKDAFM_00444 2.7e-132 kipR K Transcriptional regulator
HKKKDAFM_00445 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HKKKDAFM_00447 1.4e-49 yczJ S biosynthesis
HKKKDAFM_00448 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HKKKDAFM_00449 2.4e-172 ydhF S Oxidoreductase
HKKKDAFM_00450 0.0 mtlR K transcriptional regulator, MtlR
HKKKDAFM_00451 2.1e-293 ydaB IQ acyl-CoA ligase
HKKKDAFM_00452 9e-99 ydaC Q Methyltransferase domain
HKKKDAFM_00453 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_00454 1.5e-74 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HKKKDAFM_00455 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKKKDAFM_00456 6.8e-77 ydaG 1.4.3.5 S general stress protein
HKKKDAFM_00457 1e-137 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HKKKDAFM_00458 3.3e-46 ydzA EGP Major facilitator Superfamily
HKKKDAFM_00459 2.5e-74 lrpC K Transcriptional regulator
HKKKDAFM_00460 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKKKDAFM_00461 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HKKKDAFM_00462 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HKKKDAFM_00463 1.5e-90 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HKKKDAFM_00464 7.3e-222 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HKKKDAFM_00465 4.5e-233 ydaM M Glycosyl transferase family group 2
HKKKDAFM_00466 0.0 ydaN S Bacterial cellulose synthase subunit
HKKKDAFM_00467 0.0 ydaO E amino acid
HKKKDAFM_00468 1.9e-77 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HKKKDAFM_00469 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HKKKDAFM_00470 2.1e-39
HKKKDAFM_00471 1.3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HKKKDAFM_00473 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HKKKDAFM_00474 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HKKKDAFM_00476 8.9e-59 ydbB G Cupin domain
HKKKDAFM_00477 3.1e-62 ydbC S Domain of unknown function (DUF4937
HKKKDAFM_00478 3.5e-154 ydbD P Catalase
HKKKDAFM_00479 5.1e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HKKKDAFM_00480 4.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKKDAFM_00481 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HKKKDAFM_00482 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKKDAFM_00483 9.7e-181 ydbI S AI-2E family transporter
HKKKDAFM_00484 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HKKKDAFM_00485 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKKKDAFM_00486 2.7e-52 ydbL
HKKKDAFM_00487 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HKKKDAFM_00488 1.1e-18 S Fur-regulated basic protein B
HKKKDAFM_00489 2.2e-07 S Fur-regulated basic protein A
HKKKDAFM_00490 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKKDAFM_00491 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKKKDAFM_00492 5.1e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HKKKDAFM_00493 4.1e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HKKKDAFM_00494 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HKKKDAFM_00495 2.1e-82 ydbS S Bacterial PH domain
HKKKDAFM_00496 8.6e-260 ydbT S Membrane
HKKKDAFM_00497 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HKKKDAFM_00498 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HKKKDAFM_00499 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HKKKDAFM_00500 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKKKDAFM_00501 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HKKKDAFM_00502 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HKKKDAFM_00503 2.8e-143 rsbR T Positive regulator of sigma-B
HKKKDAFM_00504 5.2e-57 rsbS T antagonist
HKKKDAFM_00505 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HKKKDAFM_00506 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HKKKDAFM_00507 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HKKKDAFM_00508 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HKKKDAFM_00509 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_00510 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HKKKDAFM_00514 1.5e-82 ydcG S EVE domain
HKKKDAFM_00515 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_00516 0.0 yhgF K COG2183 Transcriptional accessory protein
HKKKDAFM_00517 1.6e-84 ydcK S Belongs to the SprT family
HKKKDAFM_00525 6.8e-75 rimJ2 J Acetyltransferase (GNAT) domain
HKKKDAFM_00526 8.5e-45
HKKKDAFM_00527 5.7e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKKKDAFM_00528 1.7e-32 K Helix-turn-helix XRE-family like proteins
HKKKDAFM_00529 9.6e-40
HKKKDAFM_00533 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HKKKDAFM_00534 8.7e-30 cspL K Cold shock
HKKKDAFM_00535 1.5e-77 carD K Transcription factor
HKKKDAFM_00536 4.4e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKKKDAFM_00537 1.4e-164 rhaS5 K AraC-like ligand binding domain
HKKKDAFM_00538 3.2e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HKKKDAFM_00539 1.4e-164 ydeE K AraC family transcriptional regulator
HKKKDAFM_00540 1.1e-259 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_00541 1.8e-216 ydeG EGP Major facilitator superfamily
HKKKDAFM_00542 2.7e-45 ydeH
HKKKDAFM_00543 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HKKKDAFM_00544 1.8e-108
HKKKDAFM_00545 1.1e-31 S SNARE associated Golgi protein
HKKKDAFM_00546 1.8e-14 ptsH G PTS HPr component phosphorylation site
HKKKDAFM_00547 8.8e-85 K Transcriptional regulator C-terminal region
HKKKDAFM_00548 1.8e-153 ydeK EG -transporter
HKKKDAFM_00549 2.4e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_00550 1.3e-72 maoC I N-terminal half of MaoC dehydratase
HKKKDAFM_00551 1.8e-104 ydeN S Serine hydrolase
HKKKDAFM_00552 5.7e-55 K HxlR-like helix-turn-helix
HKKKDAFM_00553 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKKKDAFM_00554 1.8e-68 ydeP K Transcriptional regulator
HKKKDAFM_00555 1.7e-110 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HKKKDAFM_00556 9.5e-193 ydeR EGP Major facilitator Superfamily
HKKKDAFM_00557 3.2e-104 ydeS K Transcriptional regulator
HKKKDAFM_00558 1.8e-56 arsR K transcriptional
HKKKDAFM_00559 2.6e-231 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKKKDAFM_00560 7.2e-149 ydfB J GNAT acetyltransferase
HKKKDAFM_00561 1e-162 ydfC EG EamA-like transporter family
HKKKDAFM_00562 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_00563 5.9e-117 ydfE S Flavin reductase like domain
HKKKDAFM_00564 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HKKKDAFM_00565 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKKKDAFM_00567 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HKKKDAFM_00568 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_00569 0.0 ydfJ S drug exporters of the RND superfamily
HKKKDAFM_00570 1.9e-177 S Alpha/beta hydrolase family
HKKKDAFM_00571 5.9e-118 S Protein of unknown function (DUF554)
HKKKDAFM_00572 3.2e-147 K Bacterial transcription activator, effector binding domain
HKKKDAFM_00573 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKKDAFM_00574 9.6e-112 ydfN C nitroreductase
HKKKDAFM_00575 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HKKKDAFM_00576 8.8e-63 mhqP S DoxX
HKKKDAFM_00577 1.3e-57 traF CO Thioredoxin
HKKKDAFM_00578 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HKKKDAFM_00579 6.3e-29
HKKKDAFM_00581 4.4e-118 ydfR S Protein of unknown function (DUF421)
HKKKDAFM_00582 5.2e-122 ydfS S Protein of unknown function (DUF421)
HKKKDAFM_00583 2.2e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HKKKDAFM_00584 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HKKKDAFM_00585 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HKKKDAFM_00586 3e-94 K Bacterial regulatory proteins, tetR family
HKKKDAFM_00587 1.6e-52 S DoxX-like family
HKKKDAFM_00588 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HKKKDAFM_00589 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HKKKDAFM_00590 2e-119 purR K helix_turn _helix lactose operon repressor
HKKKDAFM_00591 1e-190 csbC EGP Major facilitator Superfamily
HKKKDAFM_00592 4.4e-104 G Xylose isomerase-like TIM barrel
HKKKDAFM_00593 1.7e-301 expZ S ABC transporter
HKKKDAFM_00594 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_00595 2.3e-90 dinB S DinB family
HKKKDAFM_00596 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_00597 0.0 ydgH S drug exporters of the RND superfamily
HKKKDAFM_00598 8.8e-113 drgA C nitroreductase
HKKKDAFM_00599 2.4e-69 ydgJ K Winged helix DNA-binding domain
HKKKDAFM_00600 4.8e-208 tcaB EGP Major facilitator Superfamily
HKKKDAFM_00601 1.6e-121 ydhB S membrane transporter protein
HKKKDAFM_00602 6.5e-122 ydhC K FCD
HKKKDAFM_00603 6.3e-243 ydhD M Glycosyl hydrolase
HKKKDAFM_00604 2.9e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKKKDAFM_00605 4.2e-127
HKKKDAFM_00606 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKKKDAFM_00607 8.7e-68 frataxin S Domain of unknown function (DU1801)
HKKKDAFM_00609 1.5e-80 K Acetyltransferase (GNAT) domain
HKKKDAFM_00610 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HKKKDAFM_00611 2.5e-98 ydhK M Protein of unknown function (DUF1541)
HKKKDAFM_00612 4.6e-200 pbuE EGP Major facilitator Superfamily
HKKKDAFM_00613 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKKDAFM_00614 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKKDAFM_00615 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKKDAFM_00616 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKKDAFM_00617 1.1e-132 ydhQ K UTRA
HKKKDAFM_00618 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HKKKDAFM_00619 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKKKDAFM_00620 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HKKKDAFM_00621 6.1e-157 ydhU P Catalase
HKKKDAFM_00624 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00625 7.8e-08
HKKKDAFM_00627 1.3e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HKKKDAFM_00628 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HKKKDAFM_00629 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HKKKDAFM_00630 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HKKKDAFM_00631 2e-186 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HKKKDAFM_00632 0.0 ydiF S ABC transporter
HKKKDAFM_00633 2.1e-88 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HKKKDAFM_00634 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HKKKDAFM_00635 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HKKKDAFM_00636 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HKKKDAFM_00637 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HKKKDAFM_00638 7.9e-129 ydiL S CAAX protease self-immunity
HKKKDAFM_00639 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HKKKDAFM_00640 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HKKKDAFM_00642 6.4e-66 KL Phage plasmid primase P4 family
HKKKDAFM_00643 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HKKKDAFM_00644 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HKKKDAFM_00646 1.2e-199 V AAA domain (dynein-related subfamily)
HKKKDAFM_00647 4.9e-257 J LlaJI restriction endonuclease
HKKKDAFM_00648 1.1e-08 ydjC S Abhydrolase domain containing 18
HKKKDAFM_00649 0.0 K NB-ARC domain
HKKKDAFM_00650 9.4e-200 gutB 1.1.1.14 E Dehydrogenase
HKKKDAFM_00651 7.1e-256 gutA G MFS/sugar transport protein
HKKKDAFM_00652 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HKKKDAFM_00653 5.1e-114 pspA KT Phage shock protein A
HKKKDAFM_00654 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKKKDAFM_00655 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HKKKDAFM_00656 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HKKKDAFM_00657 4.7e-196 S Ion transport 2 domain protein
HKKKDAFM_00658 2.7e-258 iolT EGP Major facilitator Superfamily
HKKKDAFM_00659 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HKKKDAFM_00660 4.5e-64 ydjM M Lytic transglycolase
HKKKDAFM_00661 1.1e-155 ydjN U Involved in the tonB-independent uptake of proteins
HKKKDAFM_00662 1.4e-34 ydjO S Cold-inducible protein YdjO
HKKKDAFM_00663 8.4e-156 ydjP I Alpha/beta hydrolase family
HKKKDAFM_00664 3.3e-175 yeaA S Protein of unknown function (DUF4003)
HKKKDAFM_00665 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HKKKDAFM_00666 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_00667 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HKKKDAFM_00668 1.5e-175 yeaC S COG0714 MoxR-like ATPases
HKKKDAFM_00669 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HKKKDAFM_00670 0.0 yebA E COG1305 Transglutaminase-like enzymes
HKKKDAFM_00671 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HKKKDAFM_00672 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_00673 6.5e-252 S Domain of unknown function (DUF4179)
HKKKDAFM_00674 7.8e-212 pbuG S permease
HKKKDAFM_00675 8.3e-116 yebC M Membrane
HKKKDAFM_00677 8.9e-93 yebE S UPF0316 protein
HKKKDAFM_00678 8e-28 yebG S NETI protein
HKKKDAFM_00679 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HKKKDAFM_00680 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HKKKDAFM_00681 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HKKKDAFM_00682 3.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HKKKDAFM_00683 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKKDAFM_00684 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKKDAFM_00685 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HKKKDAFM_00686 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HKKKDAFM_00687 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HKKKDAFM_00688 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HKKKDAFM_00689 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HKKKDAFM_00690 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HKKKDAFM_00691 3.5e-73 K helix_turn_helix ASNC type
HKKKDAFM_00692 6.4e-227 yjeH E Amino acid permease
HKKKDAFM_00693 2.7e-27 S Protein of unknown function (DUF2892)
HKKKDAFM_00694 0.0 yerA 3.5.4.2 F adenine deaminase
HKKKDAFM_00695 8.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
HKKKDAFM_00696 4.8e-51 yerC S protein conserved in bacteria
HKKKDAFM_00697 8.8e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HKKKDAFM_00698 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HKKKDAFM_00699 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HKKKDAFM_00700 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HKKKDAFM_00701 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HKKKDAFM_00702 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
HKKKDAFM_00703 6.1e-123 sapB S MgtC SapB transporter
HKKKDAFM_00704 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKKDAFM_00705 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKKKDAFM_00706 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HKKKDAFM_00707 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HKKKDAFM_00708 1.3e-148 yerO K Transcriptional regulator
HKKKDAFM_00709 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HKKKDAFM_00710 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKKKDAFM_00711 1.6e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKKKDAFM_00712 0.0 L Type III restriction enzyme res subunit
HKKKDAFM_00714 5.8e-43
HKKKDAFM_00716 1.4e-100 S response regulator aspartate phosphatase
HKKKDAFM_00718 2.7e-27
HKKKDAFM_00719 4.2e-75 S Protein of unknown function, DUF600
HKKKDAFM_00720 0.0 L nucleic acid phosphodiester bond hydrolysis
HKKKDAFM_00722 8.7e-101 L endonuclease activity
HKKKDAFM_00723 2e-125 3.4.24.40 CO amine dehydrogenase activity
HKKKDAFM_00724 4.1e-26 3.4.24.40 CO amine dehydrogenase activity
HKKKDAFM_00725 1e-39
HKKKDAFM_00726 1.6e-213 S Tetratricopeptide repeat
HKKKDAFM_00728 2.7e-126 yeeN K transcriptional regulatory protein
HKKKDAFM_00730 8.5e-102 dhaR3 K Transcriptional regulator
HKKKDAFM_00731 2.5e-77 yesE S SnoaL-like domain
HKKKDAFM_00732 5.5e-142 yesF GM NAD(P)H-binding
HKKKDAFM_00733 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HKKKDAFM_00734 1.5e-45 cotJB S CotJB protein
HKKKDAFM_00735 5.2e-104 cotJC P Spore Coat
HKKKDAFM_00736 1.3e-101 yesJ K Acetyltransferase (GNAT) family
HKKKDAFM_00737 1.2e-101 yesL S Protein of unknown function, DUF624
HKKKDAFM_00738 0.0 yesM 2.7.13.3 T Histidine kinase
HKKKDAFM_00739 1.4e-201 yesN K helix_turn_helix, arabinose operon control protein
HKKKDAFM_00740 1.6e-246 yesO G Bacterial extracellular solute-binding protein
HKKKDAFM_00741 6.2e-171 yesP G Binding-protein-dependent transport system inner membrane component
HKKKDAFM_00742 7.7e-163 yesQ P Binding-protein-dependent transport system inner membrane component
HKKKDAFM_00743 2.9e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HKKKDAFM_00744 0.0 yesS K Transcriptional regulator
HKKKDAFM_00745 9.7e-129 E GDSL-like Lipase/Acylhydrolase
HKKKDAFM_00746 7.1e-129 yesU S Domain of unknown function (DUF1961)
HKKKDAFM_00747 5.2e-113 yesV S Protein of unknown function, DUF624
HKKKDAFM_00748 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HKKKDAFM_00749 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HKKKDAFM_00750 7.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
HKKKDAFM_00751 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HKKKDAFM_00752 0.0 yetA
HKKKDAFM_00753 4e-289 lplA G Bacterial extracellular solute-binding protein
HKKKDAFM_00754 5.5e-175 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HKKKDAFM_00755 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HKKKDAFM_00756 8.9e-256 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKKKDAFM_00757 4e-122 yetF S membrane
HKKKDAFM_00758 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HKKKDAFM_00759 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_00760 2.2e-34
HKKKDAFM_00761 5.4e-145 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKKDAFM_00762 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HKKKDAFM_00763 2.6e-104 yetJ S Belongs to the BI1 family
HKKKDAFM_00764 8.3e-31 yetM CH FAD binding domain
HKKKDAFM_00765 3.6e-199 yetN S Protein of unknown function (DUF3900)
HKKKDAFM_00766 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKKKDAFM_00767 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKKDAFM_00768 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HKKKDAFM_00769 1.9e-172 yfnG 4.2.1.45 M dehydratase
HKKKDAFM_00770 1.9e-180 yfnF M Nucleotide-diphospho-sugar transferase
HKKKDAFM_00771 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HKKKDAFM_00772 3.3e-188 yfnD M Nucleotide-diphospho-sugar transferase
HKKKDAFM_00773 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HKKKDAFM_00774 3.9e-133 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HKKKDAFM_00775 1.4e-240 yfnA E amino acid
HKKKDAFM_00776 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKKDAFM_00777 1.1e-113 yfmS NT chemotaxis protein
HKKKDAFM_00778 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKKDAFM_00779 3.4e-74 yfmQ S Uncharacterised protein from bacillus cereus group
HKKKDAFM_00780 4e-69 yfmP K transcriptional
HKKKDAFM_00781 1.5e-209 yfmO EGP Major facilitator Superfamily
HKKKDAFM_00782 2.1e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKKDAFM_00783 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HKKKDAFM_00784 1.6e-79 yfmK 2.3.1.128 K acetyltransferase
HKKKDAFM_00785 1.8e-187 yfmJ S N-terminal domain of oxidoreductase
HKKKDAFM_00786 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HKKKDAFM_00787 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00788 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00789 2.7e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HKKKDAFM_00790 2.9e-24 S Protein of unknown function (DUF3212)
HKKKDAFM_00791 7.6e-58 yflT S Heat induced stress protein YflT
HKKKDAFM_00792 1.1e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HKKKDAFM_00793 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HKKKDAFM_00794 1.5e-289 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKKDAFM_00795 8.9e-119 citT T response regulator
HKKKDAFM_00796 4.8e-179 yflP S Tripartite tricarboxylate transporter family receptor
HKKKDAFM_00797 1.9e-226 citM C Citrate transporter
HKKKDAFM_00798 2.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKKDAFM_00799 2.1e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HKKKDAFM_00800 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HKKKDAFM_00801 9.9e-123 yflK S protein conserved in bacteria
HKKKDAFM_00802 4e-18 yflJ S Protein of unknown function (DUF2639)
HKKKDAFM_00803 4.1e-19 yflI
HKKKDAFM_00804 5.3e-50 yflH S Protein of unknown function (DUF3243)
HKKKDAFM_00805 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HKKKDAFM_00806 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HKKKDAFM_00807 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKKDAFM_00808 6e-67 yhdN S Domain of unknown function (DUF1992)
HKKKDAFM_00809 3.1e-251 agcS_1 E Sodium alanine symporter
HKKKDAFM_00810 8.4e-25 yfkQ EG Spore germination protein
HKKKDAFM_00811 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_00812 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HKKKDAFM_00813 5.1e-133 treR K transcriptional
HKKKDAFM_00814 1.8e-124 yfkO C nitroreductase
HKKKDAFM_00815 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HKKKDAFM_00816 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
HKKKDAFM_00817 6.8e-207 ydiM EGP Major facilitator Superfamily
HKKKDAFM_00818 1.3e-28 yfkK S Belongs to the UPF0435 family
HKKKDAFM_00819 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKKKDAFM_00820 1.2e-49 yfkI S gas vesicle protein
HKKKDAFM_00821 4.8e-143 yihY S Belongs to the UPF0761 family
HKKKDAFM_00822 5e-08
HKKKDAFM_00823 2.6e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HKKKDAFM_00824 1.8e-182 cax P COG0387 Ca2 H antiporter
HKKKDAFM_00825 1.2e-146 yfkD S YfkD-like protein
HKKKDAFM_00826 6e-149 yfkC M Mechanosensitive ion channel
HKKKDAFM_00827 5.4e-222 yfkA S YfkB-like domain
HKKKDAFM_00828 1.1e-26 yfjT
HKKKDAFM_00829 1.7e-153 pdaA G deacetylase
HKKKDAFM_00830 2.1e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKKKDAFM_00831 1.7e-184 corA P Mediates influx of magnesium ions
HKKKDAFM_00832 2.2e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HKKKDAFM_00833 2e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HKKKDAFM_00834 1.6e-39 S YfzA-like protein
HKKKDAFM_00835 1.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HKKKDAFM_00836 1.1e-83 yfjM S Psort location Cytoplasmic, score
HKKKDAFM_00837 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKKDAFM_00838 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKKDAFM_00839 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKKDAFM_00840 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKKDAFM_00841 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HKKKDAFM_00842 9.8e-25 sspH S Belongs to the SspH family
HKKKDAFM_00843 4e-56 yfjF S UPF0060 membrane protein
HKKKDAFM_00844 1.1e-79 S Family of unknown function (DUF5381)
HKKKDAFM_00845 1.8e-101 yfjD S Family of unknown function (DUF5381)
HKKKDAFM_00846 4.5e-143 yfjC
HKKKDAFM_00847 9.2e-191 yfjB
HKKKDAFM_00848 7.4e-44 yfjA S Belongs to the WXG100 family
HKKKDAFM_00849 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKKKDAFM_00850 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
HKKKDAFM_00851 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_00852 6.8e-309 yfiB3 V ABC transporter
HKKKDAFM_00853 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKKDAFM_00854 6.4e-64 mhqP S DoxX
HKKKDAFM_00855 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HKKKDAFM_00856 1.5e-177 K AraC-like ligand binding domain
HKKKDAFM_00857 1.8e-262 iolT EGP Major facilitator Superfamily
HKKKDAFM_00858 8.4e-184 G Xylose isomerase
HKKKDAFM_00859 1.1e-233 S Oxidoreductase
HKKKDAFM_00861 1.1e-214 yxjM T Histidine kinase
HKKKDAFM_00862 3.2e-113 KT LuxR family transcriptional regulator
HKKKDAFM_00863 1.4e-170 V ABC transporter, ATP-binding protein
HKKKDAFM_00864 2e-206 V ABC-2 family transporter protein
HKKKDAFM_00865 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
HKKKDAFM_00866 8.3e-99 padR K transcriptional
HKKKDAFM_00867 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HKKKDAFM_00868 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HKKKDAFM_00869 7.1e-107 yfiR K Transcriptional regulator
HKKKDAFM_00870 1.5e-209 yfiS EGP Major facilitator Superfamily
HKKKDAFM_00871 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
HKKKDAFM_00872 3.4e-283 yfiU EGP Major facilitator Superfamily
HKKKDAFM_00873 5.8e-80 yfiV K transcriptional
HKKKDAFM_00874 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HKKKDAFM_00875 3.9e-176 yfiY P ABC transporter substrate-binding protein
HKKKDAFM_00876 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00877 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_00878 4e-164 yfhB 5.3.3.17 S PhzF family
HKKKDAFM_00879 1.5e-106 yfhC C nitroreductase
HKKKDAFM_00880 2.1e-25 yfhD S YfhD-like protein
HKKKDAFM_00882 1.4e-172 yfhF S nucleoside-diphosphate sugar epimerase
HKKKDAFM_00883 2.5e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HKKKDAFM_00884 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HKKKDAFM_00886 1.1e-209 yfhI EGP Major facilitator Superfamily
HKKKDAFM_00887 6.2e-20 sspK S reproduction
HKKKDAFM_00888 2.9e-44 yfhJ S WVELL protein
HKKKDAFM_00889 2.4e-87 batE T Bacterial SH3 domain homologues
HKKKDAFM_00890 3.5e-51 yfhL S SdpI/YhfL protein family
HKKKDAFM_00891 6.7e-172 yfhM S Alpha beta hydrolase
HKKKDAFM_00892 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKKDAFM_00893 0.0 yfhO S Bacterial membrane protein YfhO
HKKKDAFM_00894 3.6e-185 yfhP S membrane-bound metal-dependent
HKKKDAFM_00895 8.6e-212 mutY L A G-specific
HKKKDAFM_00896 6.9e-36 yfhS
HKKKDAFM_00897 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_00898 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HKKKDAFM_00899 1.5e-37 ygaB S YgaB-like protein
HKKKDAFM_00900 1.3e-104 ygaC J Belongs to the UPF0374 family
HKKKDAFM_00901 1.8e-301 ygaD V ABC transporter
HKKKDAFM_00902 8.7e-180 ygaE S Membrane
HKKKDAFM_00903 1.2e-244 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKKKDAFM_00904 6.3e-87 bcp 1.11.1.15 O Peroxiredoxin
HKKKDAFM_00905 4e-80 perR P Belongs to the Fur family
HKKKDAFM_00906 1.1e-54 ygzB S UPF0295 protein
HKKKDAFM_00907 3.3e-166 ygxA S Nucleotidyltransferase-like
HKKKDAFM_00908 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_00913 7.8e-08
HKKKDAFM_00921 2e-08
HKKKDAFM_00925 2.7e-143 spo0M S COG4326 Sporulation control protein
HKKKDAFM_00926 1.2e-26
HKKKDAFM_00927 1.6e-131 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HKKKDAFM_00928 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HKKKDAFM_00929 1.9e-266 ygaK C Berberine and berberine like
HKKKDAFM_00931 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKKDAFM_00932 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HKKKDAFM_00933 1.7e-171 ssuA M Sulfonate ABC transporter
HKKKDAFM_00934 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKKKDAFM_00935 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HKKKDAFM_00937 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HKKKDAFM_00938 4.1e-78 ygaO
HKKKDAFM_00939 4.4e-29 K Transcriptional regulator
HKKKDAFM_00941 7.9e-114 yhzB S B3/4 domain
HKKKDAFM_00942 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HKKKDAFM_00943 4.4e-177 yhbB S Putative amidase domain
HKKKDAFM_00944 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HKKKDAFM_00945 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HKKKDAFM_00946 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKKKDAFM_00947 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HKKKDAFM_00948 0.0 prkA T Ser protein kinase
HKKKDAFM_00949 2.5e-225 yhbH S Belongs to the UPF0229 family
HKKKDAFM_00950 2.2e-76 yhbI K DNA-binding transcription factor activity
HKKKDAFM_00951 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HKKKDAFM_00952 3.1e-271 yhcA EGP Major facilitator Superfamily
HKKKDAFM_00953 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HKKKDAFM_00954 2.8e-37 yhcC
HKKKDAFM_00955 2e-55
HKKKDAFM_00956 6.6e-60 yhcF K Transcriptional regulator
HKKKDAFM_00957 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HKKKDAFM_00958 6.5e-165 yhcH V ABC transporter, ATP-binding protein
HKKKDAFM_00959 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKKKDAFM_00960 1e-30 cspB K Cold-shock protein
HKKKDAFM_00961 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HKKKDAFM_00962 1.9e-195 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HKKKDAFM_00963 4.1e-219 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKKDAFM_00964 1.1e-77 S Protein of unknown function (DUF2812)
HKKKDAFM_00965 1.2e-49 K Transcriptional regulator PadR-like family
HKKKDAFM_00966 2e-41 yhcM
HKKKDAFM_00967 1.3e-67 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKKDAFM_00968 1.3e-166 yhcP
HKKKDAFM_00969 4.4e-99 yhcQ M Spore coat protein
HKKKDAFM_00970 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HKKKDAFM_00971 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HKKKDAFM_00972 7.3e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKKDAFM_00973 2.1e-67 yhcU S Family of unknown function (DUF5365)
HKKKDAFM_00974 9.9e-68 yhcV S COG0517 FOG CBS domain
HKKKDAFM_00975 1.3e-119 yhcW 5.4.2.6 S hydrolase
HKKKDAFM_00976 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKKKDAFM_00977 4.6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKKDAFM_00978 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HKKKDAFM_00979 5.7e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HKKKDAFM_00980 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HKKKDAFM_00981 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HKKKDAFM_00982 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HKKKDAFM_00983 3.4e-138 yhcY 2.7.13.3 T Histidine kinase
HKKKDAFM_00984 4.2e-49 yhcY 2.7.13.3 T Histidine kinase
HKKKDAFM_00985 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_00986 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HKKKDAFM_00987 1.2e-38 yhdB S YhdB-like protein
HKKKDAFM_00988 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HKKKDAFM_00989 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKKDAFM_00990 1e-75 nsrR K Transcriptional regulator
HKKKDAFM_00991 3.6e-237 ygxB M Conserved TM helix
HKKKDAFM_00992 6.3e-276 ycgB S Stage V sporulation protein R
HKKKDAFM_00993 5e-254 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HKKKDAFM_00994 1e-139 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKKDAFM_00995 3.8e-162 citR K Transcriptional regulator
HKKKDAFM_00996 1.2e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
HKKKDAFM_00997 3e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_00998 3.4e-250 yhdG E amino acid
HKKKDAFM_00999 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKKKDAFM_01000 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_01001 2e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_01002 8.1e-45 yhdK S Sigma-M inhibitor protein
HKKKDAFM_01003 6.6e-201 yhdL S Sigma factor regulator N-terminal
HKKKDAFM_01004 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_01005 2.2e-190 yhdN C Aldo keto reductase
HKKKDAFM_01006 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKKKDAFM_01007 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_01008 4.1e-74 cueR K transcriptional
HKKKDAFM_01009 1.4e-220 yhdR 2.6.1.1 E Aminotransferase
HKKKDAFM_01010 2.1e-239 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_01011 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKKKDAFM_01012 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HKKKDAFM_01013 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKKDAFM_01015 1.6e-202 yhdY M Mechanosensitive ion channel
HKKKDAFM_01016 4.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HKKKDAFM_01017 5.3e-137 yheN G deacetylase
HKKKDAFM_01018 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HKKKDAFM_01019 3.7e-225 nhaC C Na H antiporter
HKKKDAFM_01020 5.4e-82 nhaX T Belongs to the universal stress protein A family
HKKKDAFM_01021 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKKDAFM_01022 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKKDAFM_01023 7.6e-109 yheG GM NAD(P)H-binding
HKKKDAFM_01024 6.3e-28 sspB S spore protein
HKKKDAFM_01025 1.3e-36 yheE S Family of unknown function (DUF5342)
HKKKDAFM_01026 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HKKKDAFM_01027 4.3e-216 yheC HJ YheC/D like ATP-grasp
HKKKDAFM_01028 6.3e-202 yheB S Belongs to the UPF0754 family
HKKKDAFM_01029 9.5e-48 yheA S Belongs to the UPF0342 family
HKKKDAFM_01030 7.5e-205 yhaZ L DNA alkylation repair enzyme
HKKKDAFM_01031 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HKKKDAFM_01032 1.8e-292 hemZ H coproporphyrinogen III oxidase
HKKKDAFM_01033 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HKKKDAFM_01034 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKKKDAFM_01036 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
HKKKDAFM_01037 7e-26 S YhzD-like protein
HKKKDAFM_01038 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
HKKKDAFM_01039 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HKKKDAFM_01040 2.6e-225 yhaO L DNA repair exonuclease
HKKKDAFM_01041 0.0 yhaN L AAA domain
HKKKDAFM_01042 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HKKKDAFM_01043 1.6e-21 yhaL S Sporulation protein YhaL
HKKKDAFM_01044 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HKKKDAFM_01045 7.3e-89 yhaK S Putative zincin peptidase
HKKKDAFM_01046 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HKKKDAFM_01047 2.3e-113 hpr K Negative regulator of protease production and sporulation
HKKKDAFM_01048 7e-39 yhaH S YtxH-like protein
HKKKDAFM_01049 5.4e-21
HKKKDAFM_01050 3.6e-80 trpP S Tryptophan transporter TrpP
HKKKDAFM_01051 8.4e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HKKKDAFM_01052 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HKKKDAFM_01053 4.6e-137 ecsA V transporter (ATP-binding protein)
HKKKDAFM_01054 1.8e-215 ecsB U ABC transporter
HKKKDAFM_01055 1.4e-114 ecsC S EcsC protein family
HKKKDAFM_01056 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HKKKDAFM_01057 2.7e-231 yhfA C membrane
HKKKDAFM_01058 7.9e-27 1.15.1.2 C Rubrerythrin
HKKKDAFM_01059 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HKKKDAFM_01060 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKKKDAFM_01061 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HKKKDAFM_01062 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HKKKDAFM_01063 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HKKKDAFM_01064 5.4e-101 yhgD K Transcriptional regulator
HKKKDAFM_01065 2.5e-237 yhgE S YhgE Pip N-terminal domain protein
HKKKDAFM_01066 4.3e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKKKDAFM_01067 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HKKKDAFM_01068 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HKKKDAFM_01069 1.7e-72 3.4.13.21 S ASCH
HKKKDAFM_01070 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HKKKDAFM_01071 2e-140 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HKKKDAFM_01072 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
HKKKDAFM_01073 1.9e-110 yhfK GM NmrA-like family
HKKKDAFM_01074 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKKKDAFM_01075 1.9e-65 yhfM
HKKKDAFM_01076 3.5e-241 yhfN 3.4.24.84 O Peptidase M48
HKKKDAFM_01077 5.6e-198 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HKKKDAFM_01078 3.1e-75 VY92_01935 K acetyltransferase
HKKKDAFM_01079 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
HKKKDAFM_01080 1.6e-158 yfmC M Periplasmic binding protein
HKKKDAFM_01081 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HKKKDAFM_01082 5.5e-195 vraB 2.3.1.9 I Belongs to the thiolase family
HKKKDAFM_01083 6.4e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HKKKDAFM_01084 6.5e-91 bioY S BioY family
HKKKDAFM_01085 1.7e-182 hemAT NT chemotaxis protein
HKKKDAFM_01086 4.7e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HKKKDAFM_01087 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_01088 1.3e-32 yhzC S IDEAL
HKKKDAFM_01089 4.2e-109 comK K Competence transcription factor
HKKKDAFM_01090 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_01091 7.8e-42 yhjA S Excalibur calcium-binding domain
HKKKDAFM_01092 1.3e-263 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKKDAFM_01093 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HKKKDAFM_01094 6.7e-60 yhjD
HKKKDAFM_01095 3.4e-109 yhjE S SNARE associated Golgi protein
HKKKDAFM_01096 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HKKKDAFM_01097 2.4e-278 yhjG CH FAD binding domain
HKKKDAFM_01098 3.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_01099 7.6e-214 glcP G Major Facilitator Superfamily
HKKKDAFM_01100 3.2e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HKKKDAFM_01101 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HKKKDAFM_01102 1.1e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HKKKDAFM_01103 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
HKKKDAFM_01104 1.6e-200 abrB S membrane
HKKKDAFM_01105 1.9e-212 EGP Transmembrane secretion effector
HKKKDAFM_01106 0.0 S Sugar transport-related sRNA regulator N-term
HKKKDAFM_01107 2.2e-78 yhjR S Rubrerythrin
HKKKDAFM_01108 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HKKKDAFM_01109 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HKKKDAFM_01110 4.1e-220 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HKKKDAFM_01111 0.0 sbcC L COG0419 ATPase involved in DNA repair
HKKKDAFM_01112 1.1e-49 yisB V COG1403 Restriction endonuclease
HKKKDAFM_01113 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HKKKDAFM_01114 1.5e-65 gerPE S Spore germination protein GerPE
HKKKDAFM_01115 6.3e-24 gerPD S Spore germination protein
HKKKDAFM_01116 1.8e-54 gerPC S Spore germination protein
HKKKDAFM_01117 4e-34 gerPB S cell differentiation
HKKKDAFM_01118 1.9e-33 gerPA S Spore germination protein
HKKKDAFM_01119 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HKKKDAFM_01120 4.1e-175 cotH M Spore Coat
HKKKDAFM_01121 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HKKKDAFM_01122 3e-57 yisL S UPF0344 protein
HKKKDAFM_01123 0.0 wprA O Belongs to the peptidase S8 family
HKKKDAFM_01124 2.1e-102 yisN S Protein of unknown function (DUF2777)
HKKKDAFM_01125 0.0 asnO 6.3.5.4 E Asparagine synthase
HKKKDAFM_01126 3.9e-87 yizA S Damage-inducible protein DinB
HKKKDAFM_01127 2.8e-148 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HKKKDAFM_01128 1.5e-242 yisQ V Mate efflux family protein
HKKKDAFM_01129 1.2e-160 yisR K Transcriptional regulator
HKKKDAFM_01130 1.5e-183 purR K helix_turn _helix lactose operon repressor
HKKKDAFM_01131 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HKKKDAFM_01132 7e-92 yisT S DinB family
HKKKDAFM_01133 1.9e-107 argO S Lysine exporter protein LysE YggA
HKKKDAFM_01134 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HKKKDAFM_01135 4e-36 mcbG S Pentapeptide repeats (9 copies)
HKKKDAFM_01136 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKKKDAFM_01137 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HKKKDAFM_01138 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKKKDAFM_01139 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKKKDAFM_01140 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
HKKKDAFM_01141 5.4e-141 yitD 4.4.1.19 S synthase
HKKKDAFM_01142 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKKKDAFM_01143 2.7e-221 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKKKDAFM_01144 2e-228 yitG EGP Major facilitator Superfamily
HKKKDAFM_01145 3e-156 yitH K Acetyltransferase (GNAT) domain
HKKKDAFM_01146 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
HKKKDAFM_01147 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HKKKDAFM_01148 3.3e-54 yajQ S Belongs to the UPF0234 family
HKKKDAFM_01149 6.9e-161 cvfB S protein conserved in bacteria
HKKKDAFM_01150 8.5e-94
HKKKDAFM_01151 1.4e-170
HKKKDAFM_01152 1.5e-97 S Sporulation delaying protein SdpA
HKKKDAFM_01153 1.5e-58 K Transcriptional regulator PadR-like family
HKKKDAFM_01154 6.6e-94
HKKKDAFM_01155 1.4e-44 yitR S Domain of unknown function (DUF3784)
HKKKDAFM_01156 6.7e-311 nprB 3.4.24.28 E Peptidase M4
HKKKDAFM_01157 8.4e-159 yitS S protein conserved in bacteria
HKKKDAFM_01158 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HKKKDAFM_01159 5e-73 ipi S Intracellular proteinase inhibitor
HKKKDAFM_01160 1.2e-17 S Protein of unknown function (DUF3813)
HKKKDAFM_01161 4.6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HKKKDAFM_01162 8.4e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HKKKDAFM_01163 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HKKKDAFM_01164 1.5e-22 pilT S Proteolipid membrane potential modulator
HKKKDAFM_01165 6e-266 yitY C D-arabinono-1,4-lactone oxidase
HKKKDAFM_01166 1.7e-88 norB G Major Facilitator Superfamily
HKKKDAFM_01167 1.2e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HKKKDAFM_01168 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HKKKDAFM_01169 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HKKKDAFM_01170 6e-216 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HKKKDAFM_01171 9.7e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKKKDAFM_01172 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HKKKDAFM_01173 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HKKKDAFM_01174 9.5e-28 yjzC S YjzC-like protein
HKKKDAFM_01175 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HKKKDAFM_01176 6.8e-141 yjaU I carboxylic ester hydrolase activity
HKKKDAFM_01177 1.8e-101 yjaV
HKKKDAFM_01178 1.1e-183 med S Transcriptional activator protein med
HKKKDAFM_01179 4.7e-25 comZ S ComZ
HKKKDAFM_01180 2.7e-22 yjzB
HKKKDAFM_01181 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HKKKDAFM_01182 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HKKKDAFM_01183 7.8e-151 yjaZ O Zn-dependent protease
HKKKDAFM_01184 1.8e-184 appD P Belongs to the ABC transporter superfamily
HKKKDAFM_01185 6.5e-187 appF E Belongs to the ABC transporter superfamily
HKKKDAFM_01186 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HKKKDAFM_01187 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01188 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01189 6.5e-147 yjbA S Belongs to the UPF0736 family
HKKKDAFM_01190 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HKKKDAFM_01191 0.0 oppA E ABC transporter substrate-binding protein
HKKKDAFM_01192 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01193 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01194 1.5e-197 oppD P Belongs to the ABC transporter superfamily
HKKKDAFM_01195 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HKKKDAFM_01196 1.8e-210 yjbB EGP Major Facilitator Superfamily
HKKKDAFM_01197 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_01198 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HKKKDAFM_01199 6e-112 yjbE P Integral membrane protein TerC family
HKKKDAFM_01200 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKKKDAFM_01201 2.1e-221 yjbF S Competence protein
HKKKDAFM_01202 0.0 pepF E oligoendopeptidase F
HKKKDAFM_01203 1.8e-20
HKKKDAFM_01205 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKKKDAFM_01206 1.1e-71 yjbI S Bacterial-like globin
HKKKDAFM_01207 3.8e-83 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKKKDAFM_01208 1e-99 yjbK S protein conserved in bacteria
HKKKDAFM_01209 1.6e-61 yjbL S Belongs to the UPF0738 family
HKKKDAFM_01210 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HKKKDAFM_01211 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKKKDAFM_01212 2.3e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKKDAFM_01213 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HKKKDAFM_01214 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HKKKDAFM_01215 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HKKKDAFM_01216 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HKKKDAFM_01217 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
HKKKDAFM_01218 2.6e-29 thiS H thiamine diphosphate biosynthetic process
HKKKDAFM_01219 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HKKKDAFM_01220 5.1e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKKKDAFM_01221 2.2e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKKKDAFM_01222 9.5e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HKKKDAFM_01223 5.9e-54 yjbX S Spore coat protein
HKKKDAFM_01224 5.2e-83 cotZ S Spore coat protein
HKKKDAFM_01225 3.4e-96 cotY S Spore coat protein Z
HKKKDAFM_01226 1.4e-38 cotX S Spore Coat Protein X and V domain
HKKKDAFM_01227 1.4e-10 cotW
HKKKDAFM_01228 1.4e-23 cotV S Spore Coat Protein X and V domain
HKKKDAFM_01229 1.9e-56 yjcA S Protein of unknown function (DUF1360)
HKKKDAFM_01232 4.9e-38 spoVIF S Stage VI sporulation protein F
HKKKDAFM_01233 0.0 yjcD 3.6.4.12 L DNA helicase
HKKKDAFM_01234 1.7e-38
HKKKDAFM_01235 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_01236 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HKKKDAFM_01237 2.9e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
HKKKDAFM_01238 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKKDAFM_01239 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKKDAFM_01240 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
HKKKDAFM_01241 1.3e-210 yjcL S Protein of unknown function (DUF819)
HKKKDAFM_01244 7.8e-190 S Putative amidase domain
HKKKDAFM_01245 2.6e-44 yjcN
HKKKDAFM_01248 8.5e-81 L Transposase
HKKKDAFM_01249 5.3e-71 yjcP
HKKKDAFM_01250 4.1e-49 S YjcQ protein
HKKKDAFM_01251 1.1e-92 yqaS L DNA packaging
HKKKDAFM_01252 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HKKKDAFM_01253 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_01255 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HKKKDAFM_01256 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HKKKDAFM_01257 8.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HKKKDAFM_01258 4.5e-49 yjdF S Protein of unknown function (DUF2992)
HKKKDAFM_01259 4.5e-91 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HKKKDAFM_01261 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HKKKDAFM_01262 4.2e-29 S Domain of unknown function (DUF4177)
HKKKDAFM_01263 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HKKKDAFM_01264 1.4e-173 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKKKDAFM_01266 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HKKKDAFM_01267 1.4e-81 S Protein of unknown function (DUF2690)
HKKKDAFM_01268 8.9e-20 yjfB S Putative motility protein
HKKKDAFM_01269 5.6e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
HKKKDAFM_01270 1.2e-45 T PhoQ Sensor
HKKKDAFM_01271 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HKKKDAFM_01272 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HKKKDAFM_01273 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HKKKDAFM_01274 8.7e-07 S Domain of unknown function (DUF4352)
HKKKDAFM_01275 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HKKKDAFM_01277 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HKKKDAFM_01278 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HKKKDAFM_01279 8.2e-30
HKKKDAFM_01280 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKKKDAFM_01281 1.9e-122 ybbM S transport system, permease component
HKKKDAFM_01282 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HKKKDAFM_01283 2.3e-176 yjlA EG Putative multidrug resistance efflux transporter
HKKKDAFM_01284 6.4e-90 yjlB S Cupin domain
HKKKDAFM_01285 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HKKKDAFM_01286 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HKKKDAFM_01287 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HKKKDAFM_01288 8.6e-246 yjmB G symporter YjmB
HKKKDAFM_01289 1e-187 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HKKKDAFM_01290 2.5e-189 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HKKKDAFM_01291 8.9e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HKKKDAFM_01292 6.8e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_01293 6.3e-227 exuT G Sugar (and other) transporter
HKKKDAFM_01294 5.2e-184 exuR K transcriptional
HKKKDAFM_01295 4.1e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HKKKDAFM_01296 1e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HKKKDAFM_01297 7.4e-130 MA20_18170 S membrane transporter protein
HKKKDAFM_01298 2.3e-78 yjoA S DinB family
HKKKDAFM_01299 4.7e-246 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HKKKDAFM_01300 1e-212 S response regulator aspartate phosphatase
HKKKDAFM_01302 5.2e-37 S YCII-related domain
HKKKDAFM_01303 6.8e-165 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HKKKDAFM_01304 1.8e-60 yjqA S Bacterial PH domain
HKKKDAFM_01305 2.1e-111 yjqB S Pfam:DUF867
HKKKDAFM_01306 9.8e-160 ydbD P Catalase
HKKKDAFM_01307 4.3e-109 xkdA E IrrE N-terminal-like domain
HKKKDAFM_01308 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HKKKDAFM_01310 5e-156 xkdB K sequence-specific DNA binding
HKKKDAFM_01311 9.2e-118 xkdC L Bacterial dnaA protein
HKKKDAFM_01314 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HKKKDAFM_01315 2.2e-82 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HKKKDAFM_01316 5.3e-139 xtmA L phage terminase small subunit
HKKKDAFM_01317 1.4e-253 xtmB S phage terminase, large subunit
HKKKDAFM_01318 4.1e-204 yqbA S portal protein
HKKKDAFM_01319 5.7e-49 yqbA S portal protein
HKKKDAFM_01320 3.5e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HKKKDAFM_01321 1.3e-168 xkdG S Phage capsid family
HKKKDAFM_01322 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HKKKDAFM_01323 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HKKKDAFM_01324 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HKKKDAFM_01325 1.9e-77 xkdJ
HKKKDAFM_01326 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HKKKDAFM_01327 6.1e-76 xkdM S Phage tail tube protein
HKKKDAFM_01328 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HKKKDAFM_01329 0.0 xkdO L Transglycosylase SLT domain
HKKKDAFM_01330 4.1e-121 xkdP S Lysin motif
HKKKDAFM_01331 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HKKKDAFM_01332 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HKKKDAFM_01333 3.1e-69 xkdS S Protein of unknown function (DUF2634)
HKKKDAFM_01334 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKKKDAFM_01335 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKKKDAFM_01336 1.5e-40
HKKKDAFM_01337 1e-261
HKKKDAFM_01338 5.4e-53 xkdW S XkdW protein
HKKKDAFM_01339 5.5e-22 xkdX
HKKKDAFM_01340 1.7e-151 xepA
HKKKDAFM_01341 6.2e-39 xhlA S Haemolysin XhlA
HKKKDAFM_01342 9.3e-40 xhlB S SPP1 phage holin
HKKKDAFM_01343 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKKDAFM_01344 6.7e-23 spoIISB S Stage II sporulation protein SB
HKKKDAFM_01345 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HKKKDAFM_01346 5.8e-175 pit P phosphate transporter
HKKKDAFM_01347 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HKKKDAFM_01348 4e-240 steT E amino acid
HKKKDAFM_01349 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HKKKDAFM_01350 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKKKDAFM_01351 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKKDAFM_01353 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKKDAFM_01354 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HKKKDAFM_01355 2.5e-152 dppA E D-aminopeptidase
HKKKDAFM_01356 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01357 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HKKKDAFM_01358 1.3e-187 dppD P Belongs to the ABC transporter superfamily
HKKKDAFM_01359 0.0 dppE E ABC transporter substrate-binding protein
HKKKDAFM_01361 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HKKKDAFM_01362 2.3e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HKKKDAFM_01363 1e-162 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKKKDAFM_01364 9.4e-186 ykfD E Belongs to the ABC transporter superfamily
HKKKDAFM_01365 5.3e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
HKKKDAFM_01366 2e-160 ykgA E Amidinotransferase
HKKKDAFM_01367 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HKKKDAFM_01368 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HKKKDAFM_01369 5.5e-09
HKKKDAFM_01370 2.3e-128 ykjA S Protein of unknown function (DUF421)
HKKKDAFM_01371 4.8e-96 ykkA S Protein of unknown function (DUF664)
HKKKDAFM_01372 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKKKDAFM_01373 3.5e-55 ykkC P Multidrug resistance protein
HKKKDAFM_01374 7e-50 ykkD P Multidrug resistance protein
HKKKDAFM_01375 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HKKKDAFM_01376 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKKKDAFM_01377 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HKKKDAFM_01378 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HKKKDAFM_01379 4.8e-73 ohrR K COG1846 Transcriptional regulators
HKKKDAFM_01380 2.4e-71 ohrB O Organic hydroperoxide resistance protein
HKKKDAFM_01381 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HKKKDAFM_01382 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HKKKDAFM_01383 1.6e-174 isp O Belongs to the peptidase S8 family
HKKKDAFM_01384 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKKDAFM_01385 5.3e-136 ykoC P Cobalt transport protein
HKKKDAFM_01386 1.6e-302 P ABC transporter, ATP-binding protein
HKKKDAFM_01387 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HKKKDAFM_01388 5.1e-110 ykoF S YKOF-related Family
HKKKDAFM_01389 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_01390 2e-242 ykoH 2.7.13.3 T Histidine kinase
HKKKDAFM_01391 1.2e-112 ykoI S Peptidase propeptide and YPEB domain
HKKKDAFM_01392 9.7e-59 ykoJ S Peptidase propeptide and YPEB domain
HKKKDAFM_01395 2.2e-222 mgtE P Acts as a magnesium transporter
HKKKDAFM_01396 1.4e-53 tnrA K transcriptional
HKKKDAFM_01397 5.9e-18
HKKKDAFM_01398 6.9e-26 ykoL
HKKKDAFM_01399 1.3e-81 mhqR K transcriptional
HKKKDAFM_01400 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HKKKDAFM_01401 2.7e-97 ykoP G polysaccharide deacetylase
HKKKDAFM_01402 2.3e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HKKKDAFM_01403 0.0 ykoS
HKKKDAFM_01404 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKKDAFM_01405 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HKKKDAFM_01406 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HKKKDAFM_01407 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HKKKDAFM_01408 5.4e-110 ykoX S membrane-associated protein
HKKKDAFM_01409 3e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HKKKDAFM_01410 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_01411 9.1e-116 rsgI S Anti-sigma factor N-terminus
HKKKDAFM_01412 1.9e-26 sspD S small acid-soluble spore protein
HKKKDAFM_01413 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HKKKDAFM_01414 3.5e-155 htpX O Belongs to the peptidase M48B family
HKKKDAFM_01415 1.1e-232 ktrB P COG0168 Trk-type K transport systems, membrane components
HKKKDAFM_01416 1.2e-10 ydfR S Protein of unknown function (DUF421)
HKKKDAFM_01417 4.1e-18 ykzE
HKKKDAFM_01418 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HKKKDAFM_01419 0.0 kinE 2.7.13.3 T Histidine kinase
HKKKDAFM_01420 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HKKKDAFM_01422 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HKKKDAFM_01423 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HKKKDAFM_01424 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HKKKDAFM_01425 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
HKKKDAFM_01426 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HKKKDAFM_01427 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HKKKDAFM_01428 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HKKKDAFM_01429 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HKKKDAFM_01430 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
HKKKDAFM_01431 6.4e-09 S Spo0E like sporulation regulatory protein
HKKKDAFM_01432 1.8e-64 eag
HKKKDAFM_01433 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKKDAFM_01434 1.3e-75 ykvE K transcriptional
HKKKDAFM_01435 2.5e-125 motB N Flagellar motor protein
HKKKDAFM_01436 1e-137 motA N flagellar motor
HKKKDAFM_01437 0.0 clpE O Belongs to the ClpA ClpB family
HKKKDAFM_01438 2.6e-178 ykvI S membrane
HKKKDAFM_01439 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HKKKDAFM_01440 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HKKKDAFM_01441 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HKKKDAFM_01442 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HKKKDAFM_01443 2e-61 ykvN K Transcriptional regulator
HKKKDAFM_01444 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_01445 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
HKKKDAFM_01446 3.5e-35 3.5.1.104 M LysM domain
HKKKDAFM_01447 1.4e-162 G Glycosyl hydrolases family 18
HKKKDAFM_01448 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HKKKDAFM_01449 6e-25 ykvS S protein conserved in bacteria
HKKKDAFM_01450 2.8e-28
HKKKDAFM_01451 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
HKKKDAFM_01452 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_01453 1.6e-88 stoA CO thiol-disulfide
HKKKDAFM_01454 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKKKDAFM_01455 2.3e-09
HKKKDAFM_01456 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKKKDAFM_01457 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
HKKKDAFM_01459 2.2e-127 glcT K antiterminator
HKKKDAFM_01460 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_01461 2.1e-39 ptsH G phosphocarrier protein HPr
HKKKDAFM_01462 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HKKKDAFM_01463 7.2e-39 splA S Transcriptional regulator
HKKKDAFM_01464 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
HKKKDAFM_01465 3.2e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_01466 3.2e-262 mcpC NT chemotaxis protein
HKKKDAFM_01467 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HKKKDAFM_01468 8e-124 ykwD J protein with SCP PR1 domains
HKKKDAFM_01469 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HKKKDAFM_01470 0.0 pilS 2.7.13.3 T Histidine kinase
HKKKDAFM_01471 2e-222 patA 2.6.1.1 E Aminotransferase
HKKKDAFM_01472 2.2e-15
HKKKDAFM_01473 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HKKKDAFM_01474 1.7e-84 ykyB S YkyB-like protein
HKKKDAFM_01475 1.7e-235 ykuC EGP Major facilitator Superfamily
HKKKDAFM_01476 1.5e-86 ykuD S protein conserved in bacteria
HKKKDAFM_01477 1.6e-165 ykuE S Metallophosphoesterase
HKKKDAFM_01478 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_01479 5.2e-234 ykuI T Diguanylate phosphodiesterase
HKKKDAFM_01480 3.9e-37 ykuJ S protein conserved in bacteria
HKKKDAFM_01481 4.4e-94 ykuK S Ribonuclease H-like
HKKKDAFM_01482 3.9e-27 ykzF S Antirepressor AbbA
HKKKDAFM_01483 1.6e-76 ykuL S CBS domain
HKKKDAFM_01484 3.5e-168 ccpC K Transcriptional regulator
HKKKDAFM_01485 1.6e-85 fld C Flavodoxin domain
HKKKDAFM_01486 5.7e-174 ykuO
HKKKDAFM_01487 3.9e-78 fld C Flavodoxin
HKKKDAFM_01488 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HKKKDAFM_01489 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HKKKDAFM_01490 9e-37 ykuS S Belongs to the UPF0180 family
HKKKDAFM_01491 8.8e-142 ykuT M Mechanosensitive ion channel
HKKKDAFM_01492 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HKKKDAFM_01493 7e-80 ykuV CO thiol-disulfide
HKKKDAFM_01494 5.8e-95 rok K Repressor of ComK
HKKKDAFM_01495 4.2e-146 yknT
HKKKDAFM_01496 3.3e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HKKKDAFM_01497 6.5e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HKKKDAFM_01498 8.1e-246 moeA 2.10.1.1 H molybdopterin
HKKKDAFM_01499 1.3e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HKKKDAFM_01500 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HKKKDAFM_01501 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HKKKDAFM_01502 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKKDAFM_01503 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HKKKDAFM_01504 1e-117 yknW S Yip1 domain
HKKKDAFM_01505 1.1e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HKKKDAFM_01506 2.5e-124 macB V ABC transporter, ATP-binding protein
HKKKDAFM_01507 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKKKDAFM_01508 3.1e-136 fruR K Transcriptional regulator
HKKKDAFM_01509 3.1e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HKKKDAFM_01510 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HKKKDAFM_01511 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKKDAFM_01512 8.1e-39 ykoA
HKKKDAFM_01513 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HKKKDAFM_01514 1.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKKKDAFM_01515 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HKKKDAFM_01516 1.1e-12 S Uncharacterized protein YkpC
HKKKDAFM_01517 7.7e-183 mreB D Rod-share determining protein MreBH
HKKKDAFM_01518 1.5e-43 abrB K of stationary sporulation gene expression
HKKKDAFM_01519 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKKDAFM_01520 3.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HKKKDAFM_01521 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HKKKDAFM_01522 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HKKKDAFM_01523 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKKKDAFM_01524 8.2e-31 ykzG S Belongs to the UPF0356 family
HKKKDAFM_01525 1.4e-147 ykrA S hydrolases of the HAD superfamily
HKKKDAFM_01526 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKKKDAFM_01528 2e-115 recN L Putative cell-wall binding lipoprotein
HKKKDAFM_01529 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKKDAFM_01530 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKKDAFM_01531 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKKDAFM_01532 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKKDAFM_01533 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HKKKDAFM_01534 3.5e-277 speA 4.1.1.19 E Arginine
HKKKDAFM_01535 1.6e-42 yktA S Belongs to the UPF0223 family
HKKKDAFM_01536 7.1e-118 yktB S Belongs to the UPF0637 family
HKKKDAFM_01537 7.1e-26 ykzI
HKKKDAFM_01538 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HKKKDAFM_01539 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HKKKDAFM_01540 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HKKKDAFM_01541 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HKKKDAFM_01542 0.0 ylaA
HKKKDAFM_01543 2.7e-42 ylaB
HKKKDAFM_01544 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_01545 1.2e-11 sigC S Putative zinc-finger
HKKKDAFM_01546 1.8e-38 ylaE
HKKKDAFM_01547 8.2e-22 S Family of unknown function (DUF5325)
HKKKDAFM_01548 0.0 typA T GTP-binding protein TypA
HKKKDAFM_01549 4.2e-47 ylaH S YlaH-like protein
HKKKDAFM_01550 2.5e-32 ylaI S protein conserved in bacteria
HKKKDAFM_01551 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKKDAFM_01552 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HKKKDAFM_01553 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HKKKDAFM_01554 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HKKKDAFM_01555 8.7e-44 ylaN S Belongs to the UPF0358 family
HKKKDAFM_01556 4.5e-214 ftsW D Belongs to the SEDS family
HKKKDAFM_01557 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HKKKDAFM_01558 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HKKKDAFM_01559 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HKKKDAFM_01560 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HKKKDAFM_01561 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKKKDAFM_01562 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HKKKDAFM_01563 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HKKKDAFM_01564 3.4e-166 ctaG S cytochrome c oxidase
HKKKDAFM_01565 7e-62 ylbA S YugN-like family
HKKKDAFM_01566 2.6e-74 ylbB T COG0517 FOG CBS domain
HKKKDAFM_01567 9.6e-200 ylbC S protein with SCP PR1 domains
HKKKDAFM_01568 4.1e-63 ylbD S Putative coat protein
HKKKDAFM_01569 2.5e-36 ylbE S YlbE-like protein
HKKKDAFM_01570 1.8e-75 ylbF S Belongs to the UPF0342 family
HKKKDAFM_01571 3.7e-38 ylbG S UPF0298 protein
HKKKDAFM_01572 5.1e-97 rsmD 2.1.1.171 L Methyltransferase
HKKKDAFM_01573 1.1e-220 ylbJ S Sporulation integral membrane protein YlbJ
HKKKDAFM_01574 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HKKKDAFM_01575 6.8e-187 ylbL T Belongs to the peptidase S16 family
HKKKDAFM_01576 4e-234 ylbM S Belongs to the UPF0348 family
HKKKDAFM_01578 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HKKKDAFM_01579 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HKKKDAFM_01580 9.1e-72 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HKKKDAFM_01581 1.5e-88 ylbP K n-acetyltransferase
HKKKDAFM_01582 6.1e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HKKKDAFM_01583 3.2e-308 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HKKKDAFM_01584 2.9e-78 mraZ K Belongs to the MraZ family
HKKKDAFM_01585 4.7e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HKKKDAFM_01586 3.7e-44 ftsL D Essential cell division protein
HKKKDAFM_01587 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HKKKDAFM_01588 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HKKKDAFM_01589 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HKKKDAFM_01590 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HKKKDAFM_01591 1.9e-253 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HKKKDAFM_01592 5.7e-186 spoVE D Belongs to the SEDS family
HKKKDAFM_01593 6.7e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HKKKDAFM_01594 5.3e-167 murB 1.3.1.98 M cell wall formation
HKKKDAFM_01595 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HKKKDAFM_01596 4.1e-103 ylxW S protein conserved in bacteria
HKKKDAFM_01597 2.6e-90 ylxX S protein conserved in bacteria
HKKKDAFM_01598 2.8e-55 sbp S small basic protein
HKKKDAFM_01599 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HKKKDAFM_01600 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HKKKDAFM_01601 0.0 bpr O COG1404 Subtilisin-like serine proteases
HKKKDAFM_01602 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HKKKDAFM_01603 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_01604 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_01605 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HKKKDAFM_01606 1.7e-251 argE 3.5.1.16 E Acetylornithine deacetylase
HKKKDAFM_01607 2.4e-37 ylmC S sporulation protein
HKKKDAFM_01608 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HKKKDAFM_01609 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HKKKDAFM_01610 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HKKKDAFM_01611 1.6e-39 yggT S membrane
HKKKDAFM_01612 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HKKKDAFM_01613 2.6e-67 divIVA D Cell division initiation protein
HKKKDAFM_01614 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HKKKDAFM_01615 3.8e-63 dksA T COG1734 DnaK suppressor protein
HKKKDAFM_01616 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HKKKDAFM_01617 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HKKKDAFM_01618 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HKKKDAFM_01619 2.6e-231 pyrP F Xanthine uracil
HKKKDAFM_01620 8.5e-165 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HKKKDAFM_01621 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HKKKDAFM_01622 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HKKKDAFM_01623 0.0 carB 6.3.5.5 F Belongs to the CarB family
HKKKDAFM_01624 4.5e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HKKKDAFM_01625 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HKKKDAFM_01626 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HKKKDAFM_01627 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HKKKDAFM_01629 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HKKKDAFM_01630 1.2e-178 cysP P phosphate transporter
HKKKDAFM_01631 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HKKKDAFM_01632 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HKKKDAFM_01633 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HKKKDAFM_01634 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HKKKDAFM_01635 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HKKKDAFM_01636 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HKKKDAFM_01637 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HKKKDAFM_01638 3.1e-156 yloC S stress-induced protein
HKKKDAFM_01639 1.5e-40 ylzA S Belongs to the UPF0296 family
HKKKDAFM_01640 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HKKKDAFM_01641 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HKKKDAFM_01642 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HKKKDAFM_01643 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HKKKDAFM_01644 5.1e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HKKKDAFM_01645 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HKKKDAFM_01646 8.4e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HKKKDAFM_01647 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HKKKDAFM_01648 1.6e-140 stp 3.1.3.16 T phosphatase
HKKKDAFM_01649 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HKKKDAFM_01650 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HKKKDAFM_01651 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HKKKDAFM_01652 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HKKKDAFM_01653 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HKKKDAFM_01654 5.5e-59 asp S protein conserved in bacteria
HKKKDAFM_01655 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
HKKKDAFM_01656 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HKKKDAFM_01657 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HKKKDAFM_01658 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HKKKDAFM_01659 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HKKKDAFM_01660 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HKKKDAFM_01661 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HKKKDAFM_01662 6.7e-128 IQ reductase
HKKKDAFM_01663 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HKKKDAFM_01664 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HKKKDAFM_01665 0.0 smc D Required for chromosome condensation and partitioning
HKKKDAFM_01666 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HKKKDAFM_01667 3.5e-85
HKKKDAFM_01668 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HKKKDAFM_01669 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HKKKDAFM_01670 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HKKKDAFM_01671 4.5e-36 ylqC S Belongs to the UPF0109 family
HKKKDAFM_01672 6.3e-61 ylqD S YlqD protein
HKKKDAFM_01673 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HKKKDAFM_01674 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HKKKDAFM_01675 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HKKKDAFM_01676 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HKKKDAFM_01677 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKKKDAFM_01678 1.4e-288 ylqG
HKKKDAFM_01679 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HKKKDAFM_01680 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HKKKDAFM_01681 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HKKKDAFM_01682 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HKKKDAFM_01683 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HKKKDAFM_01684 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HKKKDAFM_01685 2.5e-169 xerC L tyrosine recombinase XerC
HKKKDAFM_01686 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HKKKDAFM_01687 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HKKKDAFM_01688 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HKKKDAFM_01689 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HKKKDAFM_01690 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HKKKDAFM_01691 1.9e-31 fliE N Flagellar hook-basal body
HKKKDAFM_01692 1.6e-254 fliF N The M ring may be actively involved in energy transduction
HKKKDAFM_01693 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKKDAFM_01694 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HKKKDAFM_01695 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HKKKDAFM_01696 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HKKKDAFM_01697 2.2e-36 ylxF S MgtE intracellular N domain
HKKKDAFM_01698 5.1e-220 fliK N Flagellar hook-length control protein
HKKKDAFM_01699 2.3e-72 flgD N Flagellar basal body rod modification protein
HKKKDAFM_01700 8.2e-140 flgG N Flagellar basal body rod
HKKKDAFM_01701 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HKKKDAFM_01702 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKKDAFM_01703 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HKKKDAFM_01704 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HKKKDAFM_01705 2.7e-96 fliZ N Flagellar biosynthesis protein, FliO
HKKKDAFM_01706 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HKKKDAFM_01707 2.2e-36 fliQ N Role in flagellar biosynthesis
HKKKDAFM_01708 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HKKKDAFM_01709 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKKKDAFM_01710 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HKKKDAFM_01711 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HKKKDAFM_01712 4.1e-156 flhG D Belongs to the ParA family
HKKKDAFM_01713 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HKKKDAFM_01714 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HKKKDAFM_01715 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HKKKDAFM_01716 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HKKKDAFM_01717 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HKKKDAFM_01718 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_01719 3.1e-76 ylxL
HKKKDAFM_01720 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HKKKDAFM_01721 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HKKKDAFM_01722 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HKKKDAFM_01723 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HKKKDAFM_01724 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HKKKDAFM_01725 7.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HKKKDAFM_01726 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HKKKDAFM_01727 7.7e-233 rasP M zinc metalloprotease
HKKKDAFM_01728 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HKKKDAFM_01729 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HKKKDAFM_01730 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HKKKDAFM_01731 1.1e-203 nusA K Participates in both transcription termination and antitermination
HKKKDAFM_01732 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HKKKDAFM_01733 3.1e-47 ylxQ J ribosomal protein
HKKKDAFM_01734 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HKKKDAFM_01735 3e-44 ylxP S protein conserved in bacteria
HKKKDAFM_01736 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HKKKDAFM_01737 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HKKKDAFM_01738 1.1e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HKKKDAFM_01739 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HKKKDAFM_01740 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HKKKDAFM_01741 1.5e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HKKKDAFM_01742 4.4e-233 pepR S Belongs to the peptidase M16 family
HKKKDAFM_01743 2.6e-42 ymxH S YlmC YmxH family
HKKKDAFM_01744 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HKKKDAFM_01745 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HKKKDAFM_01746 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HKKKDAFM_01747 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKKKDAFM_01748 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HKKKDAFM_01749 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HKKKDAFM_01750 9.2e-61 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HKKKDAFM_01751 3.1e-50 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HKKKDAFM_01752 4.4e-32 S YlzJ-like protein
HKKKDAFM_01753 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HKKKDAFM_01754 1.4e-133 ymfC K Transcriptional regulator
HKKKDAFM_01755 3.8e-205 ymfD EGP Major facilitator Superfamily
HKKKDAFM_01756 2.5e-231 ymfF S Peptidase M16
HKKKDAFM_01757 1.9e-242 ymfH S zinc protease
HKKKDAFM_01758 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HKKKDAFM_01759 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HKKKDAFM_01760 2.7e-143 ymfK S Protein of unknown function (DUF3388)
HKKKDAFM_01761 1.9e-124 ymfM S protein conserved in bacteria
HKKKDAFM_01762 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HKKKDAFM_01763 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HKKKDAFM_01764 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HKKKDAFM_01765 2e-211 pbpX V Beta-lactamase
HKKKDAFM_01766 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HKKKDAFM_01767 5.5e-152 ymdB S protein conserved in bacteria
HKKKDAFM_01768 1.2e-36 spoVS S Stage V sporulation protein S
HKKKDAFM_01769 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HKKKDAFM_01770 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKKKDAFM_01771 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HKKKDAFM_01772 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HKKKDAFM_01773 2.2e-88 cotE S Spore coat protein
HKKKDAFM_01774 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HKKKDAFM_01775 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HKKKDAFM_01780 9.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
HKKKDAFM_01781 2.6e-73 L Phage integrase family
HKKKDAFM_01782 2.3e-15 S PIN domain
HKKKDAFM_01783 9.7e-21
HKKKDAFM_01785 2.2e-59 S HNH endonuclease
HKKKDAFM_01786 3.8e-08
HKKKDAFM_01787 2.1e-64 S Phage terminase, small subunit
HKKKDAFM_01788 4.6e-08 S Terminase
HKKKDAFM_01789 5.1e-70 S Regulatory protein YrvL
HKKKDAFM_01791 7.9e-97 ymcC S Membrane
HKKKDAFM_01792 3.3e-104 pksA K Transcriptional regulator
HKKKDAFM_01793 4.4e-61 ymzB
HKKKDAFM_01794 2.8e-162 ymaE S Metallo-beta-lactamase superfamily
HKKKDAFM_01795 8.6e-251 aprX O Belongs to the peptidase S8 family
HKKKDAFM_01796 1.9e-07 K Transcriptional regulator
HKKKDAFM_01797 2.1e-126 ymaC S Replication protein
HKKKDAFM_01798 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
HKKKDAFM_01799 8.9e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HKKKDAFM_01800 5.4e-50 ebrA P Small Multidrug Resistance protein
HKKKDAFM_01802 2.1e-46 ymaF S YmaF family
HKKKDAFM_01803 2.1e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HKKKDAFM_01804 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HKKKDAFM_01805 8.2e-23
HKKKDAFM_01806 4.5e-22 ymzA
HKKKDAFM_01807 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HKKKDAFM_01808 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKKKDAFM_01809 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HKKKDAFM_01810 2e-109 ymaB
HKKKDAFM_01811 2.6e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKKDAFM_01812 1.7e-176 spoVK O stage V sporulation protein K
HKKKDAFM_01813 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HKKKDAFM_01814 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HKKKDAFM_01815 1.1e-68 glnR K transcriptional
HKKKDAFM_01816 7e-261 glnA 6.3.1.2 E glutamine synthetase
HKKKDAFM_01817 8.2e-133 L Belongs to the 'phage' integrase family
HKKKDAFM_01818 5e-44 E Zn peptidase
HKKKDAFM_01819 3.1e-25 K Helix-turn-helix XRE-family like proteins
HKKKDAFM_01821 4.7e-23
HKKKDAFM_01823 1.9e-81 S Phage regulatory protein Rha (Phage_pRha)
HKKKDAFM_01824 8.2e-13
HKKKDAFM_01826 2e-82 L DnaD domain protein
HKKKDAFM_01827 1.1e-24 S Loader and inhibitor of phage G40P
HKKKDAFM_01828 2e-170 dnaB 3.6.4.12 L replicative DNA helicase
HKKKDAFM_01829 4e-23
HKKKDAFM_01830 2e-18
HKKKDAFM_01831 5.3e-19 S Phage-like element PBSX protein XtrA
HKKKDAFM_01832 5.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
HKKKDAFM_01833 2.6e-73 L Phage integrase family
HKKKDAFM_01835 7.2e-22 cotD S Inner spore coat protein D
HKKKDAFM_01836 6.2e-22 S Inner spore coat protein D
HKKKDAFM_01838 4.4e-28
HKKKDAFM_01841 3.1e-49 V HNH endonuclease
HKKKDAFM_01843 3.1e-79 L phage terminase small subunit
HKKKDAFM_01844 6.4e-307 S Terminase
HKKKDAFM_01846 6.9e-237 S Phage portal protein
HKKKDAFM_01847 2.4e-117 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HKKKDAFM_01848 5e-208 S capsid protein
HKKKDAFM_01849 3.9e-17
HKKKDAFM_01850 3.4e-38 S Phage gp6-like head-tail connector protein
HKKKDAFM_01851 6.1e-38 S Phage head-tail joining protein
HKKKDAFM_01852 1.4e-50 S Bacteriophage HK97-gp10, putative tail-component
HKKKDAFM_01854 3.4e-77 S Phage tail tube protein
HKKKDAFM_01857 0.0 D phage tail tape measure protein
HKKKDAFM_01858 3.4e-112 S Phage tail protein
HKKKDAFM_01859 2.2e-219 NU Prophage endopeptidase tail
HKKKDAFM_01860 0.0 S Peptidase_G2, IMC autoproteolytic cleavage domain
HKKKDAFM_01861 4.7e-112 S Domain of unknown function (DUF2479)
HKKKDAFM_01863 2.4e-08 S Phage uncharacterised protein (Phage_XkdX)
HKKKDAFM_01864 1.6e-57 S Bacteriophage holin family
HKKKDAFM_01865 1.7e-126 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HKKKDAFM_01866 2.4e-24 S SMI1-KNR4 cell-wall
HKKKDAFM_01867 2.6e-160 M nucleic acid phosphodiester bond hydrolysis
HKKKDAFM_01868 2.6e-107 S aspartate phosphatase
HKKKDAFM_01872 1.1e-09
HKKKDAFM_01873 1.6e-31
HKKKDAFM_01874 2.1e-16
HKKKDAFM_01875 8.9e-90 G SMI1-KNR4 cell-wall
HKKKDAFM_01876 3.1e-113 ynaC
HKKKDAFM_01877 4.1e-11 S Protein of unknown function (DUF1433)
HKKKDAFM_01878 2e-97 ynaD J Acetyltransferase (GNAT) domain
HKKKDAFM_01879 4.1e-73 S CAAX protease self-immunity
HKKKDAFM_01880 4.7e-08 S Uncharacterised protein family (UPF0715)
HKKKDAFM_01881 5.5e-20 K Cro/C1-type HTH DNA-binding domain
HKKKDAFM_01882 2.1e-117 ynaE S Domain of unknown function (DUF3885)
HKKKDAFM_01883 8.6e-15 ynaF
HKKKDAFM_01885 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HKKKDAFM_01886 7.9e-255 xynT G MFS/sugar transport protein
HKKKDAFM_01887 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKKDAFM_01888 6.8e-212 xylR GK ROK family
HKKKDAFM_01889 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HKKKDAFM_01890 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HKKKDAFM_01891 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
HKKKDAFM_01892 1.4e-254 iolT EGP Major facilitator Superfamily
HKKKDAFM_01893 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HKKKDAFM_01895 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HKKKDAFM_01896 5.2e-15
HKKKDAFM_01899 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKKKDAFM_01901 8.9e-128 S Domain of unknown function, YrpD
HKKKDAFM_01904 7.9e-25 tatA U protein secretion
HKKKDAFM_01905 1.8e-71
HKKKDAFM_01906 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HKKKDAFM_01909 2.8e-52 gerAA EG Spore germination protein
HKKKDAFM_01910 1.8e-146 gerAA EG Spore germination protein
HKKKDAFM_01911 3.4e-88 gerLC S Spore germination protein
HKKKDAFM_01912 7.7e-154 yndG S DoxX-like family
HKKKDAFM_01913 2.6e-117 yndH S Domain of unknown function (DUF4166)
HKKKDAFM_01914 0.0 yndJ S YndJ-like protein
HKKKDAFM_01916 8.6e-139 yndL S Replication protein
HKKKDAFM_01917 5.8e-74 yndM S Protein of unknown function (DUF2512)
HKKKDAFM_01918 1.3e-75 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HKKKDAFM_01919 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HKKKDAFM_01920 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HKKKDAFM_01921 5e-111 yneB L resolvase
HKKKDAFM_01922 1.3e-32 ynzC S UPF0291 protein
HKKKDAFM_01923 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HKKKDAFM_01924 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HKKKDAFM_01925 1.8e-28 yneF S UPF0154 protein
HKKKDAFM_01926 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HKKKDAFM_01927 7.1e-127 ccdA O cytochrome c biogenesis protein
HKKKDAFM_01928 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HKKKDAFM_01929 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HKKKDAFM_01930 4.2e-74 yneK S Protein of unknown function (DUF2621)
HKKKDAFM_01931 1.2e-64 hspX O Spore coat protein
HKKKDAFM_01932 3.9e-19 sspP S Belongs to the SspP family
HKKKDAFM_01933 2.2e-14 sspO S Belongs to the SspO family
HKKKDAFM_01934 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HKKKDAFM_01935 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HKKKDAFM_01937 3.1e-08 sspN S Small acid-soluble spore protein N family
HKKKDAFM_01938 3.9e-35 tlp S Belongs to the Tlp family
HKKKDAFM_01939 2e-73 yneP S Thioesterase-like superfamily
HKKKDAFM_01940 1.7e-53 yneQ
HKKKDAFM_01941 4.1e-49 yneR S Belongs to the HesB IscA family
HKKKDAFM_01942 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HKKKDAFM_01943 8.6e-69 yccU S CoA-binding protein
HKKKDAFM_01944 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKKKDAFM_01945 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HKKKDAFM_01946 2.3e-12
HKKKDAFM_01947 1.3e-57 ynfC
HKKKDAFM_01948 1.8e-251 agcS E Sodium alanine symporter
HKKKDAFM_01949 9.9e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HKKKDAFM_01951 1.1e-250 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HKKKDAFM_01952 7.8e-296 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HKKKDAFM_01953 1.6e-79 yngA S membrane
HKKKDAFM_01954 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKKDAFM_01955 5.5e-104 yngC S membrane-associated protein
HKKKDAFM_01956 2.6e-230 nrnB S phosphohydrolase (DHH superfamily)
HKKKDAFM_01957 1.5e-286 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKKKDAFM_01958 6.4e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKKKDAFM_01959 2.9e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HKKKDAFM_01960 2.5e-30 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HKKKDAFM_01961 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HKKKDAFM_01962 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKKKDAFM_01963 1.2e-208 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HKKKDAFM_01964 5e-303 yngK T Glycosyl hydrolase-like 10
HKKKDAFM_01965 4e-63 yngL S Protein of unknown function (DUF1360)
HKKKDAFM_01966 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HKKKDAFM_01967 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_01968 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_01969 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_01970 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_01971 1.4e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HKKKDAFM_01972 5.6e-191 yoxA 5.1.3.3 G Aldose 1-epimerase
HKKKDAFM_01973 2.3e-246 yoeA V MATE efflux family protein
HKKKDAFM_01974 2.6e-97 yoeB S IseA DL-endopeptidase inhibitor
HKKKDAFM_01976 2.2e-96 L Integrase
HKKKDAFM_01977 3e-34 yoeD G Helix-turn-helix domain
HKKKDAFM_01978 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKKKDAFM_01979 2.3e-156 gltR1 K Transcriptional regulator
HKKKDAFM_01980 8e-185 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HKKKDAFM_01981 6.6e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HKKKDAFM_01982 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HKKKDAFM_01983 3.9e-154 gltC K Transcriptional regulator
HKKKDAFM_01984 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HKKKDAFM_01985 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKKDAFM_01986 2e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HKKKDAFM_01987 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_01988 7e-39 yoxC S Bacterial protein of unknown function (DUF948)
HKKKDAFM_01989 2.5e-130 yoxB
HKKKDAFM_01990 5.6e-92 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HKKKDAFM_01991 3.8e-126 V ABC-2 family transporter protein
HKKKDAFM_01992 2.9e-94 V ABC-2 family transporter protein
HKKKDAFM_01993 1.8e-138 V AAA domain, putative AbiEii toxin, Type IV TA system
HKKKDAFM_01994 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_01995 1.2e-233 yoaB EGP Major facilitator Superfamily
HKKKDAFM_01996 5.3e-278 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HKKKDAFM_01997 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKKDAFM_01998 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKKDAFM_01999 6.6e-32 yoaF
HKKKDAFM_02000 3e-172 iolT EGP Major facilitator Superfamily
HKKKDAFM_02001 1.6e-205 S Oxidoreductase family, C-terminal alpha/beta domain
HKKKDAFM_02002 3.2e-151 iolE 4.2.1.44 G Xylose isomerase-like TIM barrel
HKKKDAFM_02003 3.3e-90 purR K Transcriptional regulator
HKKKDAFM_02004 2.2e-07
HKKKDAFM_02005 7e-14
HKKKDAFM_02006 1.5e-38 S Protein of unknown function (DUF4025)
HKKKDAFM_02007 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
HKKKDAFM_02008 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HKKKDAFM_02009 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HKKKDAFM_02010 2.3e-111 yoaK S Membrane
HKKKDAFM_02011 2.5e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HKKKDAFM_02012 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HKKKDAFM_02014 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
HKKKDAFM_02017 7.3e-86
HKKKDAFM_02018 9.3e-172 yoaR V vancomycin resistance protein
HKKKDAFM_02019 2.8e-74 yoaS S Protein of unknown function (DUF2975)
HKKKDAFM_02020 4.4e-30 yozG K Transcriptional regulator
HKKKDAFM_02021 5.3e-147 yoaT S Protein of unknown function (DUF817)
HKKKDAFM_02022 8.6e-159 yoaU K LysR substrate binding domain
HKKKDAFM_02023 1.5e-158 yijE EG EamA-like transporter family
HKKKDAFM_02024 1.8e-77 yoaW
HKKKDAFM_02025 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HKKKDAFM_02026 3.8e-165 bla 3.5.2.6 V beta-lactamase
HKKKDAFM_02028 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HKKKDAFM_02029 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HKKKDAFM_02031 3.2e-45
HKKKDAFM_02033 2.7e-176 T PhoQ Sensor
HKKKDAFM_02034 1.2e-63 kdpC 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HKKKDAFM_02035 0.0 kdpB 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HKKKDAFM_02036 2.9e-272 kdpA 3.6.3.12 P Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HKKKDAFM_02038 2.8e-84 S SMI1-KNR4 cell-wall
HKKKDAFM_02039 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKKKDAFM_02040 9.1e-101 yokH G SMI1 / KNR4 family
HKKKDAFM_02041 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HKKKDAFM_02042 0.0 yobO M Pectate lyase superfamily protein
HKKKDAFM_02043 1.4e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HKKKDAFM_02044 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
HKKKDAFM_02045 5.3e-141 yobR 2.3.1.1 J FR47-like protein
HKKKDAFM_02046 1.3e-97 yobS K Transcriptional regulator
HKKKDAFM_02047 2.8e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKKDAFM_02048 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
HKKKDAFM_02049 1.8e-170 yobV K WYL domain
HKKKDAFM_02050 1.8e-90 yobW
HKKKDAFM_02051 1e-51 czrA K transcriptional
HKKKDAFM_02052 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HKKKDAFM_02053 1.5e-92 yozB S membrane
HKKKDAFM_02054 1.3e-142
HKKKDAFM_02055 1.2e-93 yocC
HKKKDAFM_02056 1.5e-188 yocD 3.4.17.13 V peptidase S66
HKKKDAFM_02057 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HKKKDAFM_02058 1.7e-196 desK 2.7.13.3 T Histidine kinase
HKKKDAFM_02059 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_02060 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HKKKDAFM_02061 0.0 recQ 3.6.4.12 L DNA helicase
HKKKDAFM_02062 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKKKDAFM_02063 3.3e-83 dksA T general stress protein
HKKKDAFM_02064 6.4e-54 yocL
HKKKDAFM_02065 6.6e-34
HKKKDAFM_02066 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HKKKDAFM_02067 1.1e-40 yozN
HKKKDAFM_02068 1.9e-36 yocN
HKKKDAFM_02069 4.2e-56 yozO S Bacterial PH domain
HKKKDAFM_02070 2.7e-31 yozC
HKKKDAFM_02071 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HKKKDAFM_02072 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HKKKDAFM_02073 1.3e-164 sodA 1.15.1.1 P Superoxide dismutase
HKKKDAFM_02074 9.9e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HKKKDAFM_02075 8.6e-168 yocS S -transporter
HKKKDAFM_02076 3.5e-193 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HKKKDAFM_02077 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HKKKDAFM_02078 0.0 yojO P Von Willebrand factor
HKKKDAFM_02079 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HKKKDAFM_02080 1.5e-109 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HKKKDAFM_02081 4.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HKKKDAFM_02082 4.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HKKKDAFM_02083 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HKKKDAFM_02085 4.2e-245 norM V Multidrug efflux pump
HKKKDAFM_02086 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKKDAFM_02087 2.1e-125 yojG S deacetylase
HKKKDAFM_02088 2.2e-60 yojF S Protein of unknown function (DUF1806)
HKKKDAFM_02089 1.5e-43
HKKKDAFM_02090 6.6e-162 rarD S -transporter
HKKKDAFM_02091 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HKKKDAFM_02092 3.4e-09
HKKKDAFM_02093 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HKKKDAFM_02094 3.8e-66 yodA S tautomerase
HKKKDAFM_02095 1.7e-57 yodB K transcriptional
HKKKDAFM_02096 4.8e-108 yodC C nitroreductase
HKKKDAFM_02097 3.8e-113 mhqD S Carboxylesterase
HKKKDAFM_02098 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HKKKDAFM_02099 6.2e-28 S Protein of unknown function (DUF3311)
HKKKDAFM_02100 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKKDAFM_02101 1.6e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HKKKDAFM_02102 1.7e-128 yodH Q Methyltransferase
HKKKDAFM_02103 5.2e-24 yodI
HKKKDAFM_02104 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HKKKDAFM_02105 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HKKKDAFM_02106 5.3e-09
HKKKDAFM_02107 3.6e-54 yodL S YodL-like
HKKKDAFM_02108 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HKKKDAFM_02109 2.8e-24 yozD S YozD-like protein
HKKKDAFM_02111 1.4e-124 yodN
HKKKDAFM_02112 1.4e-36 yozE S Belongs to the UPF0346 family
HKKKDAFM_02113 2.9e-47 yokU S YokU-like protein, putative antitoxin
HKKKDAFM_02114 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HKKKDAFM_02115 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HKKKDAFM_02116 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HKKKDAFM_02117 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKKKDAFM_02118 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKKKDAFM_02119 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HKKKDAFM_02121 8.3e-145 yiiD K acetyltransferase
HKKKDAFM_02122 1e-256 cgeD M maturation of the outermost layer of the spore
HKKKDAFM_02123 3.5e-38 cgeC
HKKKDAFM_02124 1.2e-65 cgeA
HKKKDAFM_02125 2e-185 cgeB S Spore maturation protein
HKKKDAFM_02126 5.2e-212 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HKKKDAFM_02127 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
HKKKDAFM_02128 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HKKKDAFM_02129 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HKKKDAFM_02130 1.6e-70 ypoP K transcriptional
HKKKDAFM_02131 3.8e-222 mepA V MATE efflux family protein
HKKKDAFM_02132 5.5e-29 ypmT S Uncharacterized ympT
HKKKDAFM_02133 1.1e-98 ypmS S protein conserved in bacteria
HKKKDAFM_02134 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HKKKDAFM_02135 1.2e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HKKKDAFM_02136 8.9e-40 ypmP S Protein of unknown function (DUF2535)
HKKKDAFM_02137 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HKKKDAFM_02138 1.8e-181 pspF K Transcriptional regulator
HKKKDAFM_02139 4.2e-110 hlyIII S protein, Hemolysin III
HKKKDAFM_02140 1.1e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HKKKDAFM_02141 1.1e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HKKKDAFM_02142 1.5e-154 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HKKKDAFM_02143 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKKKDAFM_02144 7.8e-114 ypjP S YpjP-like protein
HKKKDAFM_02145 3.7e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HKKKDAFM_02146 1.7e-75 yphP S Belongs to the UPF0403 family
HKKKDAFM_02147 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HKKKDAFM_02148 3.4e-155 ypgR C COG0694 Thioredoxin-like proteins and domains
HKKKDAFM_02149 5.4e-107 ypgQ S phosphohydrolase
HKKKDAFM_02150 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HKKKDAFM_02151 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HKKKDAFM_02152 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HKKKDAFM_02153 7.9e-31 cspD K Cold-shock protein
HKKKDAFM_02154 3.8e-16 degR
HKKKDAFM_02155 1.8e-30 S Protein of unknown function (DUF2564)
HKKKDAFM_02156 2.6e-27 ypeQ S Zinc-finger
HKKKDAFM_02157 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HKKKDAFM_02158 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HKKKDAFM_02159 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HKKKDAFM_02161 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HKKKDAFM_02162 2e-07
HKKKDAFM_02163 8.5e-38 ypbS S Protein of unknown function (DUF2533)
HKKKDAFM_02164 0.0 ypbR S Dynamin family
HKKKDAFM_02166 7.4e-86 ypbQ S protein conserved in bacteria
HKKKDAFM_02167 8.2e-207 bcsA Q Naringenin-chalcone synthase
HKKKDAFM_02168 3.8e-227 pbuX F xanthine
HKKKDAFM_02169 4.4e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HKKKDAFM_02170 3.9e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HKKKDAFM_02171 1.9e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HKKKDAFM_02172 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HKKKDAFM_02173 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HKKKDAFM_02174 7.4e-186 ptxS K transcriptional
HKKKDAFM_02175 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HKKKDAFM_02176 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_02177 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HKKKDAFM_02179 1.2e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HKKKDAFM_02180 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HKKKDAFM_02181 8.2e-91 ypsA S Belongs to the UPF0398 family
HKKKDAFM_02182 5.6e-236 yprB L RNase_H superfamily
HKKKDAFM_02183 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HKKKDAFM_02184 1.2e-80 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HKKKDAFM_02185 1.9e-71 hspX O Belongs to the small heat shock protein (HSP20) family
HKKKDAFM_02186 6.6e-47 yppG S YppG-like protein
HKKKDAFM_02188 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HKKKDAFM_02191 5.4e-186 yppC S Protein of unknown function (DUF2515)
HKKKDAFM_02192 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HKKKDAFM_02193 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HKKKDAFM_02194 1.8e-92 ypoC
HKKKDAFM_02195 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HKKKDAFM_02196 1.3e-128 dnaD L DNA replication protein DnaD
HKKKDAFM_02197 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HKKKDAFM_02198 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HKKKDAFM_02199 4.9e-79 ypmB S protein conserved in bacteria
HKKKDAFM_02200 1.9e-22 ypmA S Protein of unknown function (DUF4264)
HKKKDAFM_02201 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HKKKDAFM_02202 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HKKKDAFM_02203 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HKKKDAFM_02204 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HKKKDAFM_02205 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HKKKDAFM_02206 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HKKKDAFM_02207 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HKKKDAFM_02208 1.7e-128 bshB1 S proteins, LmbE homologs
HKKKDAFM_02209 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HKKKDAFM_02210 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HKKKDAFM_02211 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HKKKDAFM_02212 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HKKKDAFM_02213 1e-142 ypjB S sporulation protein
HKKKDAFM_02214 2e-98 ypjA S membrane
HKKKDAFM_02215 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HKKKDAFM_02216 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HKKKDAFM_02217 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HKKKDAFM_02218 4.2e-77 ypiF S Protein of unknown function (DUF2487)
HKKKDAFM_02219 2.8e-99 ypiB S Belongs to the UPF0302 family
HKKKDAFM_02220 2.7e-233 S COG0457 FOG TPR repeat
HKKKDAFM_02221 4.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HKKKDAFM_02222 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HKKKDAFM_02223 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HKKKDAFM_02224 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HKKKDAFM_02225 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HKKKDAFM_02226 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HKKKDAFM_02227 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HKKKDAFM_02228 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HKKKDAFM_02229 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HKKKDAFM_02230 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HKKKDAFM_02231 8.1e-207 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HKKKDAFM_02232 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HKKKDAFM_02233 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HKKKDAFM_02234 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HKKKDAFM_02235 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKKKDAFM_02236 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HKKKDAFM_02237 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HKKKDAFM_02238 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HKKKDAFM_02239 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HKKKDAFM_02240 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HKKKDAFM_02241 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HKKKDAFM_02242 5.4e-138 yphF
HKKKDAFM_02243 1.6e-18 yphE S Protein of unknown function (DUF2768)
HKKKDAFM_02244 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HKKKDAFM_02245 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HKKKDAFM_02246 1.6e-28 ypzH
HKKKDAFM_02247 2.5e-161 seaA S YIEGIA protein
HKKKDAFM_02248 8.7e-102 yphA
HKKKDAFM_02249 1e-07 S YpzI-like protein
HKKKDAFM_02250 9e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HKKKDAFM_02251 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HKKKDAFM_02252 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HKKKDAFM_02253 1.8e-23 S Family of unknown function (DUF5359)
HKKKDAFM_02254 9.2e-113 ypfA M Flagellar protein YcgR
HKKKDAFM_02255 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HKKKDAFM_02256 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HKKKDAFM_02257 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HKKKDAFM_02258 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HKKKDAFM_02259 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKKDAFM_02260 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HKKKDAFM_02261 1.5e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
HKKKDAFM_02262 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HKKKDAFM_02263 4.6e-81 ypbE M Lysin motif
HKKKDAFM_02264 2.2e-100 ypbD S metal-dependent membrane protease
HKKKDAFM_02265 3.2e-286 recQ 3.6.4.12 L DNA helicase
HKKKDAFM_02266 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HKKKDAFM_02267 4.7e-41 fer C Ferredoxin
HKKKDAFM_02268 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HKKKDAFM_02269 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKKDAFM_02270 2.2e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HKKKDAFM_02271 7.3e-195 rsiX
HKKKDAFM_02272 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_02273 0.0 resE 2.7.13.3 T Histidine kinase
HKKKDAFM_02274 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_02275 9.7e-214 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HKKKDAFM_02276 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HKKKDAFM_02277 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HKKKDAFM_02278 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKKKDAFM_02279 1.9e-87 spmB S Spore maturation protein
HKKKDAFM_02280 3.5e-103 spmA S Spore maturation protein
HKKKDAFM_02281 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HKKKDAFM_02282 7.6e-97 ypuI S Protein of unknown function (DUF3907)
HKKKDAFM_02283 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HKKKDAFM_02284 2.9e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HKKKDAFM_02285 1.4e-92 ypuF S Domain of unknown function (DUF309)
HKKKDAFM_02286 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_02287 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HKKKDAFM_02288 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HKKKDAFM_02289 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HKKKDAFM_02290 2.4e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HKKKDAFM_02291 7.8e-55 ypuD
HKKKDAFM_02292 1.2e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HKKKDAFM_02293 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HKKKDAFM_02294 3.4e-13 S PAP2 superfamily
HKKKDAFM_02296 1.2e-07 eaeH M Domain of Unknown Function (DUF1259)
HKKKDAFM_02298 1.9e-25 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKKKDAFM_02299 7.3e-07
HKKKDAFM_02303 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HKKKDAFM_02304 1.3e-149 ypuA S Secreted protein
HKKKDAFM_02305 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HKKKDAFM_02306 1.4e-273 spoVAF EG Stage V sporulation protein AF
HKKKDAFM_02307 1.4e-110 spoVAEA S stage V sporulation protein
HKKKDAFM_02308 2.2e-57 spoVAEB S stage V sporulation protein
HKKKDAFM_02309 9e-192 spoVAD I Stage V sporulation protein AD
HKKKDAFM_02310 2.3e-78 spoVAC S stage V sporulation protein AC
HKKKDAFM_02311 1e-67 spoVAB S Stage V sporulation protein AB
HKKKDAFM_02312 7.4e-112 spoVAA S Stage V sporulation protein AA
HKKKDAFM_02313 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_02314 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HKKKDAFM_02315 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HKKKDAFM_02316 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HKKKDAFM_02317 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HKKKDAFM_02318 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HKKKDAFM_02319 2.6e-166 xerD L recombinase XerD
HKKKDAFM_02320 3.7e-37 S Protein of unknown function (DUF4227)
HKKKDAFM_02321 2.4e-80 fur P Belongs to the Fur family
HKKKDAFM_02322 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HKKKDAFM_02323 2.1e-29 yqkK
HKKKDAFM_02324 5.5e-242 mleA 1.1.1.38 C malic enzyme
HKKKDAFM_02325 1.1e-227 mleN C Na H antiporter
HKKKDAFM_02326 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HKKKDAFM_02327 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HKKKDAFM_02328 4.5e-58 ansR K Transcriptional regulator
HKKKDAFM_02329 1.8e-220 yqxK 3.6.4.12 L DNA helicase
HKKKDAFM_02330 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HKKKDAFM_02332 1.2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HKKKDAFM_02333 3.1e-12 yqkE S Protein of unknown function (DUF3886)
HKKKDAFM_02334 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HKKKDAFM_02335 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HKKKDAFM_02336 2.8e-54 yqkB S Belongs to the HesB IscA family
HKKKDAFM_02337 6.9e-142 yqkA K GrpB protein
HKKKDAFM_02338 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HKKKDAFM_02339 3.6e-87 yqjY K acetyltransferase
HKKKDAFM_02340 5.7e-50 S YolD-like protein
HKKKDAFM_02341 1.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKKKDAFM_02343 1.3e-224 yqjV G Major Facilitator Superfamily
HKKKDAFM_02345 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_02346 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
HKKKDAFM_02347 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HKKKDAFM_02348 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_02349 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKKDAFM_02350 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKKDAFM_02351 0.0 rocB E arginine degradation protein
HKKKDAFM_02352 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HKKKDAFM_02353 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HKKKDAFM_02354 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HKKKDAFM_02355 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HKKKDAFM_02356 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKKKDAFM_02357 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HKKKDAFM_02358 4.5e-24 yqzJ
HKKKDAFM_02359 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKKKDAFM_02360 8.9e-141 yqjF S Uncharacterized conserved protein (COG2071)
HKKKDAFM_02361 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HKKKDAFM_02362 3.8e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HKKKDAFM_02363 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HKKKDAFM_02365 1.4e-98 yqjB S protein conserved in bacteria
HKKKDAFM_02366 7.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HKKKDAFM_02367 4.5e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKKDAFM_02368 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HKKKDAFM_02369 4.1e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
HKKKDAFM_02370 9.3e-77 yqiW S Belongs to the UPF0403 family
HKKKDAFM_02371 9.8e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HKKKDAFM_02372 5.1e-207 norA EGP Major facilitator Superfamily
HKKKDAFM_02373 6.4e-151 bmrR K helix_turn_helix, mercury resistance
HKKKDAFM_02374 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HKKKDAFM_02375 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HKKKDAFM_02376 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HKKKDAFM_02377 2.8e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HKKKDAFM_02378 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HKKKDAFM_02379 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKKDAFM_02380 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HKKKDAFM_02381 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HKKKDAFM_02382 4e-34 yqzF S Protein of unknown function (DUF2627)
HKKKDAFM_02383 6.9e-159 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HKKKDAFM_02384 2.4e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HKKKDAFM_02385 8.4e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HKKKDAFM_02386 8.8e-212 mmgC I acyl-CoA dehydrogenase
HKKKDAFM_02387 4e-156 hbdA 1.1.1.157 I Dehydrogenase
HKKKDAFM_02388 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HKKKDAFM_02389 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HKKKDAFM_02390 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HKKKDAFM_02391 5.9e-27
HKKKDAFM_02392 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HKKKDAFM_02394 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HKKKDAFM_02395 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HKKKDAFM_02396 0.0 recN L May be involved in recombinational repair of damaged DNA
HKKKDAFM_02397 1.7e-78 argR K Regulates arginine biosynthesis genes
HKKKDAFM_02398 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HKKKDAFM_02399 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HKKKDAFM_02400 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HKKKDAFM_02401 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKKKDAFM_02402 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HKKKDAFM_02403 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HKKKDAFM_02404 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HKKKDAFM_02405 2.1e-67 yqhY S protein conserved in bacteria
HKKKDAFM_02406 3.4e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HKKKDAFM_02407 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HKKKDAFM_02408 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HKKKDAFM_02409 2.2e-109 spoIIIAG S stage III sporulation protein AG
HKKKDAFM_02410 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HKKKDAFM_02411 1.3e-197 spoIIIAE S stage III sporulation protein AE
HKKKDAFM_02412 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HKKKDAFM_02413 7.6e-29 spoIIIAC S stage III sporulation protein AC
HKKKDAFM_02414 1.1e-84 spoIIIAB S Stage III sporulation protein
HKKKDAFM_02415 3e-170 spoIIIAA S stage III sporulation protein AA
HKKKDAFM_02416 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HKKKDAFM_02417 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HKKKDAFM_02418 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HKKKDAFM_02419 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HKKKDAFM_02420 2.3e-93 yqhR S Conserved membrane protein YqhR
HKKKDAFM_02421 4.7e-174 yqhQ S Protein of unknown function (DUF1385)
HKKKDAFM_02422 2.2e-61 yqhP
HKKKDAFM_02423 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HKKKDAFM_02424 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HKKKDAFM_02425 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HKKKDAFM_02426 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HKKKDAFM_02427 2.4e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKKKDAFM_02428 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HKKKDAFM_02429 1.8e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HKKKDAFM_02430 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKKKDAFM_02431 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HKKKDAFM_02432 1.2e-24 sinI S Anti-repressor SinI
HKKKDAFM_02433 1e-54 sinR K transcriptional
HKKKDAFM_02434 2.5e-141 tasA S Cell division protein FtsN
HKKKDAFM_02435 2.5e-58 sipW 3.4.21.89 U Signal peptidase
HKKKDAFM_02436 2.8e-113 yqxM
HKKKDAFM_02437 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HKKKDAFM_02438 4.4e-25 yqzE S YqzE-like protein
HKKKDAFM_02439 8.8e-44 S ComG operon protein 7
HKKKDAFM_02440 1.7e-34 comGF U Putative Competence protein ComGF
HKKKDAFM_02441 2e-58 comGE
HKKKDAFM_02442 6.3e-70 gspH NU protein transport across the cell outer membrane
HKKKDAFM_02443 6.8e-47 comGC U Required for transformation and DNA binding
HKKKDAFM_02444 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
HKKKDAFM_02445 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HKKKDAFM_02447 7.2e-175 corA P Mg2 transporter protein
HKKKDAFM_02448 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_02449 7e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HKKKDAFM_02451 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HKKKDAFM_02452 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HKKKDAFM_02453 9.5e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKKDAFM_02454 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HKKKDAFM_02455 6.9e-50 yqgV S Thiamine-binding protein
HKKKDAFM_02456 2.7e-199 yqgU
HKKKDAFM_02457 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HKKKDAFM_02458 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKKDAFM_02459 5.2e-181 glcK 2.7.1.2 G Glucokinase
HKKKDAFM_02460 3.1e-33 yqgQ S Protein conserved in bacteria
HKKKDAFM_02461 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HKKKDAFM_02462 2.5e-09 yqgO
HKKKDAFM_02463 6.7e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HKKKDAFM_02464 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HKKKDAFM_02465 5.1e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HKKKDAFM_02467 3.5e-50 yqzD
HKKKDAFM_02468 7.3e-72 yqzC S YceG-like family
HKKKDAFM_02469 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKKKDAFM_02470 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HKKKDAFM_02471 4.4e-158 pstA P Phosphate transport system permease
HKKKDAFM_02472 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HKKKDAFM_02473 3.4e-150 pstS P Phosphate
HKKKDAFM_02474 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HKKKDAFM_02475 2.5e-231 yqgE EGP Major facilitator superfamily
HKKKDAFM_02476 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HKKKDAFM_02477 4e-73 yqgC S protein conserved in bacteria
HKKKDAFM_02478 3.9e-131 yqgB S Protein of unknown function (DUF1189)
HKKKDAFM_02479 5.2e-47 yqfZ M LysM domain
HKKKDAFM_02480 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HKKKDAFM_02481 4.3e-62 yqfX S membrane
HKKKDAFM_02482 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HKKKDAFM_02483 1.9e-77 zur P Belongs to the Fur family
HKKKDAFM_02484 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HKKKDAFM_02485 7.9e-36 yqfT S Protein of unknown function (DUF2624)
HKKKDAFM_02486 2.6e-166 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HKKKDAFM_02487 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HKKKDAFM_02488 3.5e-12 yqfQ S YqfQ-like protein
HKKKDAFM_02489 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HKKKDAFM_02490 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HKKKDAFM_02491 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
HKKKDAFM_02492 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HKKKDAFM_02493 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HKKKDAFM_02494 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HKKKDAFM_02495 4.5e-88 yaiI S Belongs to the UPF0178 family
HKKKDAFM_02496 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HKKKDAFM_02497 4.5e-112 ccpN K CBS domain
HKKKDAFM_02498 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HKKKDAFM_02499 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HKKKDAFM_02500 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HKKKDAFM_02501 8.4e-19 S YqzL-like protein
HKKKDAFM_02502 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HKKKDAFM_02503 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HKKKDAFM_02504 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HKKKDAFM_02505 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HKKKDAFM_02506 0.0 yqfF S membrane-associated HD superfamily hydrolase
HKKKDAFM_02508 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
HKKKDAFM_02509 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HKKKDAFM_02510 2.7e-45 yqfC S sporulation protein YqfC
HKKKDAFM_02511 2.4e-21 yqfB
HKKKDAFM_02512 4.3e-122 yqfA S UPF0365 protein
HKKKDAFM_02513 7.7e-228 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HKKKDAFM_02514 2.5e-61 yqeY S Yqey-like protein
HKKKDAFM_02515 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HKKKDAFM_02516 2.3e-157 yqeW P COG1283 Na phosphate symporter
HKKKDAFM_02517 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HKKKDAFM_02518 9.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HKKKDAFM_02519 6e-174 prmA J Methylates ribosomal protein L11
HKKKDAFM_02520 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HKKKDAFM_02521 0.0 dnaK O Heat shock 70 kDa protein
HKKKDAFM_02522 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HKKKDAFM_02523 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HKKKDAFM_02524 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
HKKKDAFM_02525 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HKKKDAFM_02526 7.2e-53 yqxA S Protein of unknown function (DUF3679)
HKKKDAFM_02527 4.5e-222 spoIIP M stage II sporulation protein P
HKKKDAFM_02528 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HKKKDAFM_02529 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HKKKDAFM_02530 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HKKKDAFM_02531 4.1e-15 S YqzM-like protein
HKKKDAFM_02532 0.0 comEC S Competence protein ComEC
HKKKDAFM_02533 4.7e-105 comEB 3.5.4.12 F ComE operon protein 2
HKKKDAFM_02534 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HKKKDAFM_02535 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HKKKDAFM_02536 2.9e-139 yqeM Q Methyltransferase
HKKKDAFM_02537 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HKKKDAFM_02538 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HKKKDAFM_02539 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HKKKDAFM_02540 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HKKKDAFM_02541 5.1e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HKKKDAFM_02542 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HKKKDAFM_02543 5.3e-95 yqeG S hydrolase of the HAD superfamily
HKKKDAFM_02545 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HKKKDAFM_02546 1.7e-131 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKKDAFM_02547 2.3e-105 yqeD S SNARE associated Golgi protein
HKKKDAFM_02548 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HKKKDAFM_02549 2e-132 yqeB
HKKKDAFM_02550 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HKKKDAFM_02551 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_02552 1.1e-278 cisA2 L Recombinase
HKKKDAFM_02553 1.7e-93 hrtA 3.6.3.25 V abc transporter atp-binding protein
HKKKDAFM_02554 8.2e-122 hrtB V ABC transporter (Permease
HKKKDAFM_02555 5.7e-189 T PhoQ Sensor
HKKKDAFM_02556 4.4e-94 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_02558 8.4e-130 S Aspartate phosphatase response regulator
HKKKDAFM_02559 1.3e-138 yvgN 1.1.1.346 S Reductase
HKKKDAFM_02560 1e-70 K MerR family transcriptional regulator
HKKKDAFM_02561 6e-228 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HKKKDAFM_02562 1.1e-26 yokK S SMI1 / KNR4 family
HKKKDAFM_02564 1.3e-14 S SMI1-KNR4 cell-wall
HKKKDAFM_02565 3.7e-47
HKKKDAFM_02566 4.6e-100 S Suppressor of fused protein (SUFU)
HKKKDAFM_02569 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HKKKDAFM_02570 2.6e-68 S Bacteriophage holin family
HKKKDAFM_02571 3e-159 xepA
HKKKDAFM_02572 3.7e-10
HKKKDAFM_02573 4.1e-56 xkdW S XkdW protein
HKKKDAFM_02574 3.4e-197
HKKKDAFM_02575 9.6e-40
HKKKDAFM_02576 4.2e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HKKKDAFM_02577 5.8e-186 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HKKKDAFM_02578 1.8e-69 xkdS S Protein of unknown function (DUF2634)
HKKKDAFM_02579 2.1e-31 xkdR S Protein of unknown function (DUF2577)
HKKKDAFM_02580 7.9e-177 yqbQ 3.2.1.96 G NLP P60 protein
HKKKDAFM_02581 2.2e-112 xkdP S Lysin motif
HKKKDAFM_02582 0.0 xkdO L Transglycosylase SLT domain
HKKKDAFM_02583 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HKKKDAFM_02585 3.6e-76 xkdM S Phage tail tube protein
HKKKDAFM_02586 1.8e-251 xkdK S Phage tail sheath C-terminal domain
HKKKDAFM_02587 6.1e-25
HKKKDAFM_02588 1.3e-73
HKKKDAFM_02589 1.9e-86 S Bacteriophage HK97-gp10, putative tail-component
HKKKDAFM_02590 6.3e-63 yqbH S Domain of unknown function (DUF3599)
HKKKDAFM_02591 5.1e-66 S Protein of unknown function (DUF3199)
HKKKDAFM_02592 4.1e-47 S YqbF, hypothetical protein domain
HKKKDAFM_02593 1.7e-165 xkdG S Phage capsid family
HKKKDAFM_02594 8.6e-115 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HKKKDAFM_02596 1.9e-156 S Phage Mu protein F like protein
HKKKDAFM_02597 2.3e-287 yqbA S portal protein
HKKKDAFM_02598 7.3e-247 S phage terminase, large subunit
HKKKDAFM_02599 1.8e-101 yqaS L DNA packaging
HKKKDAFM_02600 6.5e-12
HKKKDAFM_02602 1e-78 L Transposase
HKKKDAFM_02603 2.6e-75 S Beta protein
HKKKDAFM_02604 2.4e-54 S Psort location Cytoplasmic, score
HKKKDAFM_02605 2e-29 yqaO S Phage-like element PBSX protein XtrA
HKKKDAFM_02606 6.7e-72 rusA L Endodeoxyribonuclease RusA
HKKKDAFM_02608 1.1e-163 xkdC L IstB-like ATP binding protein
HKKKDAFM_02609 9.2e-119 3.1.3.16 L DnaD domain protein
HKKKDAFM_02610 1.8e-148 recT L RecT family
HKKKDAFM_02611 2.7e-174 yqaJ L YqaJ-like viral recombinase domain
HKKKDAFM_02615 4.4e-103
HKKKDAFM_02617 7.7e-17 K Helix-turn-helix XRE-family like proteins
HKKKDAFM_02618 9.6e-32 K sequence-specific DNA binding
HKKKDAFM_02620 1.4e-98 adk 2.7.4.3 F adenylate kinase activity
HKKKDAFM_02622 3.4e-94 yqaB E IrrE N-terminal-like domain
HKKKDAFM_02623 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HKKKDAFM_02624 3.6e-112 tetR3 K Transcriptional regulator
HKKKDAFM_02625 2e-215 mepA V Multidrug transporter MatE
HKKKDAFM_02626 7e-166 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HKKKDAFM_02627 5.4e-112 yrkJ S membrane transporter protein
HKKKDAFM_02628 3.5e-35 yrkI O Belongs to the sulfur carrier protein TusA family
HKKKDAFM_02629 9.3e-206 yrkH P Rhodanese Homology Domain
HKKKDAFM_02630 2.3e-96 yrkF OP Belongs to the sulfur carrier protein TusA family
HKKKDAFM_02631 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
HKKKDAFM_02632 7.8e-39 yrkD S protein conserved in bacteria
HKKKDAFM_02633 5.5e-106 yrkC G Cupin domain
HKKKDAFM_02634 4.2e-147 bltR K helix_turn_helix, mercury resistance
HKKKDAFM_02635 3.9e-210 blt EGP Major facilitator Superfamily
HKKKDAFM_02636 5.9e-82 bltD 2.3.1.57 K FR47-like protein
HKKKDAFM_02637 8.6e-125 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_02638 3.2e-88 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_02639 3.9e-16 S YrzO-like protein
HKKKDAFM_02640 1.6e-169 yrdR EG EamA-like transporter family
HKKKDAFM_02641 3e-159 yrdQ K Transcriptional regulator
HKKKDAFM_02642 2.3e-198 trkA P Oxidoreductase
HKKKDAFM_02643 4e-149 czcD P COG1230 Co Zn Cd efflux system component
HKKKDAFM_02644 1.3e-66 yodA S tautomerase
HKKKDAFM_02645 5e-162 gltR K LysR substrate binding domain
HKKKDAFM_02646 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
HKKKDAFM_02647 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HKKKDAFM_02648 9.6e-138 azlC E AzlC protein
HKKKDAFM_02649 5.3e-78 bkdR K helix_turn_helix ASNC type
HKKKDAFM_02650 1.1e-40 yrdF K ribonuclease inhibitor
HKKKDAFM_02651 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
HKKKDAFM_02652 3.3e-57 S Protein of unknown function (DUF2568)
HKKKDAFM_02653 2.4e-89 yrdA S DinB family
HKKKDAFM_02654 4.2e-166 aadK G Streptomycin adenylyltransferase
HKKKDAFM_02655 3.2e-192 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HKKKDAFM_02656 4.8e-148 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKKKDAFM_02657 1.6e-123 yrpD S Domain of unknown function, YrpD
HKKKDAFM_02659 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HKKKDAFM_02660 2.4e-95 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_02661 1.3e-187 yrpG C Aldo/keto reductase family
HKKKDAFM_02662 3.4e-223 yraO C Citrate transporter
HKKKDAFM_02663 3.4e-163 yraN K Transcriptional regulator
HKKKDAFM_02664 1.6e-205 yraM S PrpF protein
HKKKDAFM_02666 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HKKKDAFM_02667 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_02668 3.2e-155 S Alpha beta hydrolase
HKKKDAFM_02669 1.7e-60 T sh3 domain protein
HKKKDAFM_02670 2.4e-61 T sh3 domain protein
HKKKDAFM_02671 1.3e-66 E Glyoxalase-like domain
HKKKDAFM_02672 5.3e-37 yraG
HKKKDAFM_02673 6.4e-63 yraF M Spore coat protein
HKKKDAFM_02674 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKKKDAFM_02675 2.6e-26 yraE
HKKKDAFM_02676 1.1e-49 yraD M Spore coat protein
HKKKDAFM_02677 4.3e-47 yraB K helix_turn_helix, mercury resistance
HKKKDAFM_02678 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HKKKDAFM_02679 3.2e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HKKKDAFM_02680 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HKKKDAFM_02681 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HKKKDAFM_02682 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HKKKDAFM_02683 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HKKKDAFM_02684 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HKKKDAFM_02685 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HKKKDAFM_02686 0.0 levR K PTS system fructose IIA component
HKKKDAFM_02687 1e-254 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_02688 3.6e-106 yrhP E LysE type translocator
HKKKDAFM_02689 1.6e-149 yrhO K Archaeal transcriptional regulator TrmB
HKKKDAFM_02690 1.6e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_02691 3.8e-151 rsiV S Protein of unknown function (DUF3298)
HKKKDAFM_02692 0.0 yrhL I Acyltransferase family
HKKKDAFM_02693 1e-18 yrhK S YrhK-like protein
HKKKDAFM_02694 7.3e-29 S Butirosin biosynthesis protein H, N-terminal
HKKKDAFM_02695 3.9e-11 O Butirosin biosynthesis protein H, N-terminal
HKKKDAFM_02696 1.5e-52 S dehydrogenases and related proteins
HKKKDAFM_02697 6.6e-88 yodQ 3.5.1.16 E Acetylornithine deacetylase
HKKKDAFM_02698 1.2e-100 EF ATP-grasp domain
HKKKDAFM_02699 1.5e-180 hutH 4.3.1.23, 4.3.1.24, 4.3.1.3, 5.4.3.6 E Aromatic amino acid lyase
HKKKDAFM_02700 2e-46 hopR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HKKKDAFM_02701 7.2e-104 Q TIGRFAM amino acid adenylation domain
HKKKDAFM_02702 8.3e-63 S ABC-2 family transporter protein
HKKKDAFM_02703 5.7e-64 S ABC-2 family transporter protein
HKKKDAFM_02704 9.4e-117 S ATPases associated with a variety of cellular activities
HKKKDAFM_02705 2.6e-119 wbpP 5.1.3.2, 5.1.3.7 GM NmrA-like family
HKKKDAFM_02706 4.3e-168 capL C PFAM UDP-glucose GDP-mannose dehydrogenase
HKKKDAFM_02707 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HKKKDAFM_02708 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HKKKDAFM_02709 7.2e-95 yrhH Q methyltransferase
HKKKDAFM_02712 1.8e-142 focA P Formate nitrite
HKKKDAFM_02713 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
HKKKDAFM_02714 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HKKKDAFM_02715 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HKKKDAFM_02716 4.6e-35 yrhC S YrhC-like protein
HKKKDAFM_02717 1.1e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HKKKDAFM_02718 2.7e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HKKKDAFM_02719 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HKKKDAFM_02720 7.6e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HKKKDAFM_02721 1e-25 yrzA S Protein of unknown function (DUF2536)
HKKKDAFM_02722 1.6e-62 yrrS S Protein of unknown function (DUF1510)
HKKKDAFM_02723 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HKKKDAFM_02724 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HKKKDAFM_02725 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HKKKDAFM_02726 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HKKKDAFM_02727 3.9e-173 yegQ O Peptidase U32
HKKKDAFM_02728 2.9e-119 yrrM 2.1.1.104 S O-methyltransferase
HKKKDAFM_02729 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HKKKDAFM_02730 1.2e-45 yrzB S Belongs to the UPF0473 family
HKKKDAFM_02731 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HKKKDAFM_02732 6.5e-41 yrzL S Belongs to the UPF0297 family
HKKKDAFM_02733 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HKKKDAFM_02734 2.7e-170 yrrI S AI-2E family transporter
HKKKDAFM_02735 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKKDAFM_02736 1.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
HKKKDAFM_02737 8e-109 gluC P ABC transporter
HKKKDAFM_02738 7.6e-107 glnP P ABC transporter
HKKKDAFM_02739 8e-08 S Protein of unknown function (DUF3918)
HKKKDAFM_02740 9.8e-31 yrzR
HKKKDAFM_02741 2.5e-80 yrrD S protein conserved in bacteria
HKKKDAFM_02742 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HKKKDAFM_02743 1.4e-15 S COG0457 FOG TPR repeat
HKKKDAFM_02744 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HKKKDAFM_02745 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
HKKKDAFM_02746 1.2e-70 cymR K Transcriptional regulator
HKKKDAFM_02747 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HKKKDAFM_02748 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HKKKDAFM_02749 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HKKKDAFM_02750 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HKKKDAFM_02752 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
HKKKDAFM_02753 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HKKKDAFM_02754 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HKKKDAFM_02755 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HKKKDAFM_02756 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HKKKDAFM_02757 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HKKKDAFM_02758 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HKKKDAFM_02759 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HKKKDAFM_02760 9.4e-49 yrzD S Post-transcriptional regulator
HKKKDAFM_02761 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_02762 3e-111 yrbG S membrane
HKKKDAFM_02763 2.2e-73 yrzE S Protein of unknown function (DUF3792)
HKKKDAFM_02764 8e-39 yajC U Preprotein translocase subunit YajC
HKKKDAFM_02765 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HKKKDAFM_02766 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HKKKDAFM_02767 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HKKKDAFM_02768 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HKKKDAFM_02769 3.8e-105 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HKKKDAFM_02770 4.8e-93 bofC S BofC C-terminal domain
HKKKDAFM_02771 4.5e-252 csbX EGP Major facilitator Superfamily
HKKKDAFM_02772 4.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HKKKDAFM_02773 6.5e-119 yrzF T serine threonine protein kinase
HKKKDAFM_02775 1.3e-50 S Family of unknown function (DUF5412)
HKKKDAFM_02776 4.5e-261 alsT E Sodium alanine symporter
HKKKDAFM_02777 1e-125 yebC K transcriptional regulatory protein
HKKKDAFM_02778 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKKDAFM_02779 8.3e-157 safA M spore coat assembly protein SafA
HKKKDAFM_02780 1.1e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HKKKDAFM_02781 1.9e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HKKKDAFM_02782 2.3e-303 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HKKKDAFM_02783 4.5e-227 nifS 2.8.1.7 E Cysteine desulfurase
HKKKDAFM_02784 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HKKKDAFM_02785 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
HKKKDAFM_02786 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HKKKDAFM_02787 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HKKKDAFM_02788 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HKKKDAFM_02789 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HKKKDAFM_02790 4.1e-56 ysxB J ribosomal protein
HKKKDAFM_02791 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HKKKDAFM_02792 9.2e-161 spoIVFB S Stage IV sporulation protein
HKKKDAFM_02793 9.3e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HKKKDAFM_02794 4.7e-143 minD D Belongs to the ParA family
HKKKDAFM_02795 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HKKKDAFM_02796 1.4e-84 mreD M shape-determining protein
HKKKDAFM_02797 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HKKKDAFM_02798 1.8e-184 mreB D Rod shape-determining protein MreB
HKKKDAFM_02799 1.3e-125 radC E Belongs to the UPF0758 family
HKKKDAFM_02800 8.3e-102 maf D septum formation protein Maf
HKKKDAFM_02801 8.4e-166 spoIIB S Sporulation related domain
HKKKDAFM_02802 8.3e-126 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HKKKDAFM_02803 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HKKKDAFM_02804 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HKKKDAFM_02805 1.6e-25
HKKKDAFM_02806 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HKKKDAFM_02807 2.2e-222 spoVID M stage VI sporulation protein D
HKKKDAFM_02808 2.3e-248 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HKKKDAFM_02809 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HKKKDAFM_02810 7.1e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HKKKDAFM_02811 9.6e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HKKKDAFM_02812 3.6e-146 hemX O cytochrome C
HKKKDAFM_02813 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HKKKDAFM_02814 1.4e-89 ysxD
HKKKDAFM_02815 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HKKKDAFM_02816 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HKKKDAFM_02817 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HKKKDAFM_02818 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HKKKDAFM_02819 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HKKKDAFM_02820 2.3e-187 ysoA H Tetratricopeptide repeat
HKKKDAFM_02821 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKKKDAFM_02822 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HKKKDAFM_02823 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HKKKDAFM_02824 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HKKKDAFM_02825 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HKKKDAFM_02826 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HKKKDAFM_02827 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HKKKDAFM_02829 7.6e-82 ysnE K acetyltransferase
HKKKDAFM_02830 9.1e-134 ysnF S protein conserved in bacteria
HKKKDAFM_02832 7e-92 ysnB S Phosphoesterase
HKKKDAFM_02833 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HKKKDAFM_02834 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HKKKDAFM_02835 2.9e-196 gerM S COG5401 Spore germination protein
HKKKDAFM_02836 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HKKKDAFM_02837 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_02838 3.3e-30 gerE K Transcriptional regulator
HKKKDAFM_02839 6.5e-78 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HKKKDAFM_02840 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKKKDAFM_02841 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HKKKDAFM_02842 2.4e-107 sdhC C succinate dehydrogenase
HKKKDAFM_02843 1.2e-79 yslB S Protein of unknown function (DUF2507)
HKKKDAFM_02844 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HKKKDAFM_02845 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HKKKDAFM_02846 2e-52 trxA O Belongs to the thioredoxin family
HKKKDAFM_02847 5.7e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HKKKDAFM_02849 2.1e-177 etfA C Electron transfer flavoprotein
HKKKDAFM_02850 4.5e-135 etfB C Electron transfer flavoprotein
HKKKDAFM_02851 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HKKKDAFM_02852 2.7e-100 fadR K Transcriptional regulator
HKKKDAFM_02853 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HKKKDAFM_02854 7.3e-68 yshE S membrane
HKKKDAFM_02855 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HKKKDAFM_02856 0.0 polX L COG1796 DNA polymerase IV (family X)
HKKKDAFM_02857 1.3e-85 cvpA S membrane protein, required for colicin V production
HKKKDAFM_02858 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HKKKDAFM_02859 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HKKKDAFM_02860 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKKKDAFM_02861 2.3e-195 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HKKKDAFM_02862 9.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HKKKDAFM_02863 5.8e-32 sspI S Belongs to the SspI family
HKKKDAFM_02864 9.2e-206 ysfB KT regulator
HKKKDAFM_02865 8.2e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
HKKKDAFM_02866 5.8e-255 glcF C Glycolate oxidase
HKKKDAFM_02867 6.2e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
HKKKDAFM_02868 0.0 cstA T Carbon starvation protein
HKKKDAFM_02869 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HKKKDAFM_02870 2.2e-143 araQ G transport system permease
HKKKDAFM_02871 1.4e-167 araP G carbohydrate transport
HKKKDAFM_02872 8.1e-254 araN G carbohydrate transport
HKKKDAFM_02873 1.2e-219 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HKKKDAFM_02874 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HKKKDAFM_02875 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HKKKDAFM_02876 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HKKKDAFM_02877 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HKKKDAFM_02878 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKKDAFM_02879 2.2e-204 ysdC G COG1363 Cellulase M and related proteins
HKKKDAFM_02880 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HKKKDAFM_02881 7.5e-45 ysdA S Membrane
HKKKDAFM_02882 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HKKKDAFM_02883 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HKKKDAFM_02884 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HKKKDAFM_02886 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKKKDAFM_02887 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HKKKDAFM_02888 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HKKKDAFM_02889 0.0 lytS 2.7.13.3 T Histidine kinase
HKKKDAFM_02890 1.5e-149 ysaA S HAD-hyrolase-like
HKKKDAFM_02891 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKKKDAFM_02892 3.8e-159 ytxC S YtxC-like family
HKKKDAFM_02893 4.9e-111 ytxB S SNARE associated Golgi protein
HKKKDAFM_02894 3e-173 dnaI L Primosomal protein DnaI
HKKKDAFM_02895 3.5e-266 dnaB L Membrane attachment protein
HKKKDAFM_02896 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HKKKDAFM_02897 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HKKKDAFM_02898 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKKKDAFM_02899 9.9e-67 ytcD K Transcriptional regulator
HKKKDAFM_02900 4.9e-205 ytbD EGP Major facilitator Superfamily
HKKKDAFM_02901 8.9e-161 ytbE S reductase
HKKKDAFM_02902 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HKKKDAFM_02903 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HKKKDAFM_02904 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HKKKDAFM_02905 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HKKKDAFM_02906 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HKKKDAFM_02907 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_02908 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HKKKDAFM_02909 1.8e-242 icd 1.1.1.42 C isocitrate
HKKKDAFM_02910 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HKKKDAFM_02911 4.7e-71 yeaL S membrane
HKKKDAFM_02912 9.9e-192 ytvI S sporulation integral membrane protein YtvI
HKKKDAFM_02913 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HKKKDAFM_02914 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HKKKDAFM_02915 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HKKKDAFM_02916 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HKKKDAFM_02917 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HKKKDAFM_02918 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HKKKDAFM_02919 0.0 dnaE 2.7.7.7 L DNA polymerase
HKKKDAFM_02920 3.2e-56 ytrH S Sporulation protein YtrH
HKKKDAFM_02921 8.2e-69 ytrI
HKKKDAFM_02922 9.2e-29
HKKKDAFM_02923 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HKKKDAFM_02924 2.4e-47 ytpI S YtpI-like protein
HKKKDAFM_02925 8e-241 ytoI K transcriptional regulator containing CBS domains
HKKKDAFM_02926 1.2e-158 ytnM S membrane transporter protein
HKKKDAFM_02927 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HKKKDAFM_02928 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HKKKDAFM_02929 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_02930 4.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HKKKDAFM_02931 4.7e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_02932 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HKKKDAFM_02933 1.9e-119 tcyM U Binding-protein-dependent transport system inner membrane component
HKKKDAFM_02934 2e-121 tcyL P Binding-protein-dependent transport system inner membrane component
HKKKDAFM_02935 3.8e-145 tcyK M Bacterial periplasmic substrate-binding proteins
HKKKDAFM_02936 1.1e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
HKKKDAFM_02937 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HKKKDAFM_02938 3.6e-171 ytlI K LysR substrate binding domain
HKKKDAFM_02939 1.7e-130 ytkL S Belongs to the UPF0173 family
HKKKDAFM_02940 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_02942 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HKKKDAFM_02943 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HKKKDAFM_02944 3e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HKKKDAFM_02945 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HKKKDAFM_02946 7e-165 ytxK 2.1.1.72 L DNA methylase
HKKKDAFM_02947 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HKKKDAFM_02948 8.7e-70 ytfJ S Sporulation protein YtfJ
HKKKDAFM_02949 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HKKKDAFM_02950 1.3e-87 yteJ S RDD family
HKKKDAFM_02951 7.1e-181 sppA OU signal peptide peptidase SppA
HKKKDAFM_02952 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HKKKDAFM_02953 0.0 ytcJ S amidohydrolase
HKKKDAFM_02954 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKKKDAFM_02955 2e-29 sspB S spore protein
HKKKDAFM_02956 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HKKKDAFM_02957 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HKKKDAFM_02958 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HKKKDAFM_02959 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HKKKDAFM_02960 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HKKKDAFM_02961 1e-108 yttP K Transcriptional regulator
HKKKDAFM_02962 7.7e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HKKKDAFM_02963 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HKKKDAFM_02964 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HKKKDAFM_02966 8.8e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKKKDAFM_02967 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HKKKDAFM_02968 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HKKKDAFM_02969 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HKKKDAFM_02970 1.9e-225 acuC BQ histone deacetylase
HKKKDAFM_02971 1.4e-125 motS N Flagellar motor protein
HKKKDAFM_02972 7.1e-147 motA N flagellar motor
HKKKDAFM_02973 1.7e-182 ccpA K catabolite control protein A
HKKKDAFM_02974 1.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HKKKDAFM_02975 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
HKKKDAFM_02976 1.9e-16 ytxH S COG4980 Gas vesicle protein
HKKKDAFM_02977 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HKKKDAFM_02978 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HKKKDAFM_02979 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HKKKDAFM_02980 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HKKKDAFM_02981 9.8e-149 ytpQ S Belongs to the UPF0354 family
HKKKDAFM_02982 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HKKKDAFM_02983 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HKKKDAFM_02984 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HKKKDAFM_02985 1.1e-50 ytzB S small secreted protein
HKKKDAFM_02986 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HKKKDAFM_02987 4.2e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HKKKDAFM_02988 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HKKKDAFM_02989 2e-45 ytzH S YtzH-like protein
HKKKDAFM_02990 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HKKKDAFM_02991 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HKKKDAFM_02992 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HKKKDAFM_02993 1.3e-165 ytlQ
HKKKDAFM_02994 8.9e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HKKKDAFM_02995 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HKKKDAFM_02996 3.9e-270 pepV 3.5.1.18 E Dipeptidase
HKKKDAFM_02997 2.1e-225 pbuO S permease
HKKKDAFM_02998 9.3e-201 ythQ U Bacterial ABC transporter protein EcsB
HKKKDAFM_02999 1.4e-130 ythP V ABC transporter
HKKKDAFM_03000 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HKKKDAFM_03001 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HKKKDAFM_03002 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_03003 8.2e-232 ytfP S HI0933-like protein
HKKKDAFM_03004 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HKKKDAFM_03005 3.1e-26 yteV S Sporulation protein Cse60
HKKKDAFM_03006 1.3e-114 yteU S Integral membrane protein
HKKKDAFM_03007 3.5e-246 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HKKKDAFM_03008 5.6e-71 yteS G transport
HKKKDAFM_03009 9.5e-219 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HKKKDAFM_03010 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HKKKDAFM_03011 0.0 ytdP K Transcriptional regulator
HKKKDAFM_03012 5.2e-289 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HKKKDAFM_03013 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
HKKKDAFM_03014 1.2e-135 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HKKKDAFM_03015 1.7e-221 bioI 1.14.14.46 C Cytochrome P450
HKKKDAFM_03016 5.4e-189 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HKKKDAFM_03017 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HKKKDAFM_03018 1.8e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HKKKDAFM_03019 3.9e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HKKKDAFM_03020 5.8e-140 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HKKKDAFM_03021 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
HKKKDAFM_03022 4.3e-189 msmR K Transcriptional regulator
HKKKDAFM_03023 1.8e-245 msmE G Bacterial extracellular solute-binding protein
HKKKDAFM_03024 1.4e-167 amyD P ABC transporter
HKKKDAFM_03025 1.1e-142 amyC P ABC transporter (permease)
HKKKDAFM_03026 5.8e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HKKKDAFM_03027 2.1e-51 ytwF P Sulfurtransferase
HKKKDAFM_03028 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HKKKDAFM_03029 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HKKKDAFM_03030 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HKKKDAFM_03031 7.3e-209 yttB EGP Major facilitator Superfamily
HKKKDAFM_03032 1.3e-41 yttA 2.7.13.3 S Pfam Transposase IS66
HKKKDAFM_03033 0.0 bceB V ABC transporter (permease)
HKKKDAFM_03034 1.1e-138 bceA V ABC transporter, ATP-binding protein
HKKKDAFM_03035 1.8e-184 T PhoQ Sensor
HKKKDAFM_03036 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_03037 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKKKDAFM_03038 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HKKKDAFM_03039 5.9e-148
HKKKDAFM_03040 8.3e-166 P ABC-2 family transporter protein
HKKKDAFM_03041 4.2e-161 ytrB P abc transporter atp-binding protein
HKKKDAFM_03042 5.1e-66 ytrA K GntR family transcriptional regulator
HKKKDAFM_03044 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HKKKDAFM_03045 2.1e-190 yhcC S Fe-S oxidoreductase
HKKKDAFM_03046 3.3e-106 ytqB J Putative rRNA methylase
HKKKDAFM_03047 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HKKKDAFM_03048 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HKKKDAFM_03049 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HKKKDAFM_03050 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_03051 0.0 asnB 6.3.5.4 E Asparagine synthase
HKKKDAFM_03052 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HKKKDAFM_03053 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HKKKDAFM_03054 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HKKKDAFM_03055 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HKKKDAFM_03056 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HKKKDAFM_03057 1.4e-144 ytlC P ABC transporter
HKKKDAFM_03058 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HKKKDAFM_03059 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HKKKDAFM_03060 5.4e-63 ytkC S Bacteriophage holin family
HKKKDAFM_03061 2.1e-76 dps P Belongs to the Dps family
HKKKDAFM_03063 2.4e-72 ytkA S YtkA-like
HKKKDAFM_03064 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HKKKDAFM_03065 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKKKDAFM_03066 3.6e-41 rpmE2 J Ribosomal protein L31
HKKKDAFM_03067 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
HKKKDAFM_03068 1.2e-188 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HKKKDAFM_03069 1.1e-24 S Domain of Unknown Function (DUF1540)
HKKKDAFM_03070 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HKKKDAFM_03071 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HKKKDAFM_03072 2.1e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HKKKDAFM_03073 5.3e-167 troA P Belongs to the bacterial solute-binding protein 9 family
HKKKDAFM_03074 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HKKKDAFM_03075 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HKKKDAFM_03076 1.6e-154 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HKKKDAFM_03077 6.7e-153 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HKKKDAFM_03078 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HKKKDAFM_03079 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HKKKDAFM_03080 2.6e-132 dksA T COG1734 DnaK suppressor protein
HKKKDAFM_03081 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HKKKDAFM_03082 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKKDAFM_03083 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HKKKDAFM_03084 3.6e-235 ytcC M Glycosyltransferase Family 4
HKKKDAFM_03086 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HKKKDAFM_03087 1.8e-217 cotSA M Glycosyl transferases group 1
HKKKDAFM_03088 1.8e-206 cotI S Spore coat protein
HKKKDAFM_03089 9.9e-77 tspO T membrane
HKKKDAFM_03090 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HKKKDAFM_03091 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HKKKDAFM_03092 6.4e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HKKKDAFM_03093 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HKKKDAFM_03094 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HKKKDAFM_03103 7.8e-08
HKKKDAFM_03104 1.3e-09
HKKKDAFM_03111 2e-08
HKKKDAFM_03116 3.4e-39 S COG NOG14552 non supervised orthologous group
HKKKDAFM_03117 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HKKKDAFM_03118 1.4e-92 M1-753 M FR47-like protein
HKKKDAFM_03119 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HKKKDAFM_03120 4.2e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HKKKDAFM_03121 3.9e-84 yuaE S DinB superfamily
HKKKDAFM_03122 7.4e-106 yuaD
HKKKDAFM_03123 1.1e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
HKKKDAFM_03124 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HKKKDAFM_03125 2.7e-94 yuaC K Belongs to the GbsR family
HKKKDAFM_03126 2.2e-91 yuaB
HKKKDAFM_03127 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
HKKKDAFM_03128 1.6e-236 ktrB P Potassium
HKKKDAFM_03129 1e-38 yiaA S yiaA/B two helix domain
HKKKDAFM_03130 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKKKDAFM_03131 4.9e-274 yubD P Major Facilitator Superfamily
HKKKDAFM_03132 6.4e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HKKKDAFM_03134 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HKKKDAFM_03135 3.7e-189 yubA S transporter activity
HKKKDAFM_03136 9.7e-183 ygjR S Oxidoreductase
HKKKDAFM_03137 9.1e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HKKKDAFM_03138 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HKKKDAFM_03139 3.6e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HKKKDAFM_03140 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HKKKDAFM_03141 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HKKKDAFM_03143 2.1e-237 mcpA NT chemotaxis protein
HKKKDAFM_03144 8.5e-295 mcpA NT chemotaxis protein
HKKKDAFM_03145 6.9e-220 mcpA NT chemotaxis protein
HKKKDAFM_03146 9.3e-225 mcpA NT chemotaxis protein
HKKKDAFM_03147 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HKKKDAFM_03148 2.3e-35
HKKKDAFM_03149 2.1e-72 yugU S Uncharacterised protein family UPF0047
HKKKDAFM_03150 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HKKKDAFM_03151 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HKKKDAFM_03152 1.4e-116 yugP S Zn-dependent protease
HKKKDAFM_03153 2.3e-38
HKKKDAFM_03154 1.1e-53 mstX S Membrane-integrating protein Mistic
HKKKDAFM_03155 2.2e-182 yugO P COG1226 Kef-type K transport systems
HKKKDAFM_03156 1.3e-72 yugN S YugN-like family
HKKKDAFM_03158 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HKKKDAFM_03159 2.8e-229 yugK C Dehydrogenase
HKKKDAFM_03160 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HKKKDAFM_03161 1.1e-34 yuzA S Domain of unknown function (DUF378)
HKKKDAFM_03162 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HKKKDAFM_03163 2.1e-199 yugH 2.6.1.1 E Aminotransferase
HKKKDAFM_03164 1.6e-85 alaR K Transcriptional regulator
HKKKDAFM_03165 4.9e-156 yugF I Hydrolase
HKKKDAFM_03166 4.6e-39 yugE S Domain of unknown function (DUF1871)
HKKKDAFM_03167 6.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HKKKDAFM_03168 4.6e-233 T PhoQ Sensor
HKKKDAFM_03169 2.2e-69 kapB G Kinase associated protein B
HKKKDAFM_03170 4.2e-115 kapD L the KinA pathway to sporulation
HKKKDAFM_03172 3.8e-185 yuxJ EGP Major facilitator Superfamily
HKKKDAFM_03173 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HKKKDAFM_03174 1.8e-74 yuxK S protein conserved in bacteria
HKKKDAFM_03175 1.8e-77 yufK S Family of unknown function (DUF5366)
HKKKDAFM_03176 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HKKKDAFM_03177 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HKKKDAFM_03178 5.8e-197 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HKKKDAFM_03179 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HKKKDAFM_03180 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
HKKKDAFM_03181 1.9e-167 yufQ S Belongs to the binding-protein-dependent transport system permease family
HKKKDAFM_03182 1.3e-233 maeN C COG3493 Na citrate symporter
HKKKDAFM_03183 3.2e-14
HKKKDAFM_03184 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HKKKDAFM_03185 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKKDAFM_03186 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKKDAFM_03187 1.9e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKKDAFM_03188 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKKDAFM_03189 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HKKKDAFM_03190 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HKKKDAFM_03191 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
HKKKDAFM_03192 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_03193 0.0 comP 2.7.13.3 T Histidine kinase
HKKKDAFM_03195 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
HKKKDAFM_03198 3.2e-22 yuzC
HKKKDAFM_03199 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HKKKDAFM_03200 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HKKKDAFM_03201 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
HKKKDAFM_03202 7.9e-67 yueI S Protein of unknown function (DUF1694)
HKKKDAFM_03203 2.8e-38 yueH S YueH-like protein
HKKKDAFM_03204 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HKKKDAFM_03205 1.9e-190 yueF S transporter activity
HKKKDAFM_03206 3.7e-69 S Protein of unknown function (DUF2283)
HKKKDAFM_03207 2.9e-24 S Protein of unknown function (DUF2642)
HKKKDAFM_03208 4.8e-96 yueE S phosphohydrolase
HKKKDAFM_03209 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_03210 6.6e-65 yueC S Family of unknown function (DUF5383)
HKKKDAFM_03211 0.0 esaA S type VII secretion protein EsaA
HKKKDAFM_03212 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HKKKDAFM_03213 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HKKKDAFM_03214 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HKKKDAFM_03215 2.8e-45 esxA S Belongs to the WXG100 family
HKKKDAFM_03216 6.5e-229 yukF QT Transcriptional regulator
HKKKDAFM_03217 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HKKKDAFM_03218 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HKKKDAFM_03219 3.8e-36 mbtH S MbtH-like protein
HKKKDAFM_03220 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_03221 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HKKKDAFM_03222 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HKKKDAFM_03223 6.6e-226 entC 5.4.4.2 HQ Isochorismate synthase
HKKKDAFM_03224 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03225 1.3e-167 besA S Putative esterase
HKKKDAFM_03226 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HKKKDAFM_03227 1.3e-92 bioY S Biotin biosynthesis protein
HKKKDAFM_03228 3.9e-211 yuiF S antiporter
HKKKDAFM_03229 3.4e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HKKKDAFM_03230 1.2e-77 yuiD S protein conserved in bacteria
HKKKDAFM_03231 9.5e-118 yuiC S protein conserved in bacteria
HKKKDAFM_03232 8.4e-27 yuiB S Putative membrane protein
HKKKDAFM_03233 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HKKKDAFM_03234 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HKKKDAFM_03236 6e-185 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HKKKDAFM_03237 1e-116 paiB K Putative FMN-binding domain
HKKKDAFM_03238 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_03239 3.7e-63 erpA S Belongs to the HesB IscA family
HKKKDAFM_03240 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HKKKDAFM_03241 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKKDAFM_03242 3.2e-39 yuzB S Belongs to the UPF0349 family
HKKKDAFM_03243 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HKKKDAFM_03244 3.5e-57 yuzD S protein conserved in bacteria
HKKKDAFM_03245 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HKKKDAFM_03246 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HKKKDAFM_03247 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HKKKDAFM_03248 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HKKKDAFM_03249 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HKKKDAFM_03250 2e-199 yutH S Spore coat protein
HKKKDAFM_03251 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HKKKDAFM_03252 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HKKKDAFM_03253 1e-75 yutE S Protein of unknown function DUF86
HKKKDAFM_03254 9.7e-48 yutD S protein conserved in bacteria
HKKKDAFM_03255 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HKKKDAFM_03256 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HKKKDAFM_03257 4.5e-196 lytH M Peptidase, M23
HKKKDAFM_03258 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HKKKDAFM_03259 4.8e-48 yunC S Domain of unknown function (DUF1805)
HKKKDAFM_03260 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HKKKDAFM_03261 2e-141 yunE S membrane transporter protein
HKKKDAFM_03262 4.3e-171 yunF S Protein of unknown function DUF72
HKKKDAFM_03263 3e-62 yunG
HKKKDAFM_03264 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HKKKDAFM_03265 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HKKKDAFM_03266 2.1e-236 pbuX F Permease family
HKKKDAFM_03267 1.3e-222 pbuX F xanthine
HKKKDAFM_03268 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HKKKDAFM_03269 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HKKKDAFM_03270 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HKKKDAFM_03271 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HKKKDAFM_03272 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HKKKDAFM_03273 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HKKKDAFM_03274 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HKKKDAFM_03276 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HKKKDAFM_03277 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HKKKDAFM_03278 2.4e-169 bsn L Ribonuclease
HKKKDAFM_03279 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HKKKDAFM_03280 1.1e-135 yurK K UTRA
HKKKDAFM_03281 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HKKKDAFM_03282 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HKKKDAFM_03283 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
HKKKDAFM_03284 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HKKKDAFM_03285 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HKKKDAFM_03286 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HKKKDAFM_03287 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HKKKDAFM_03289 1e-41
HKKKDAFM_03290 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_03291 3.5e-271 sufB O FeS cluster assembly
HKKKDAFM_03292 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HKKKDAFM_03293 1.2e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HKKKDAFM_03294 1.4e-245 sufD O assembly protein SufD
HKKKDAFM_03295 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HKKKDAFM_03296 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HKKKDAFM_03297 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HKKKDAFM_03298 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HKKKDAFM_03299 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HKKKDAFM_03300 2.4e-56 yusD S SCP-2 sterol transfer family
HKKKDAFM_03301 5.6e-55 traF CO Thioredoxin
HKKKDAFM_03302 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HKKKDAFM_03303 1.1e-39 yusG S Protein of unknown function (DUF2553)
HKKKDAFM_03304 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HKKKDAFM_03305 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HKKKDAFM_03306 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HKKKDAFM_03307 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HKKKDAFM_03308 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HKKKDAFM_03309 4e-08 S YuzL-like protein
HKKKDAFM_03310 2.4e-164 fadM E Proline dehydrogenase
HKKKDAFM_03311 5.1e-40
HKKKDAFM_03312 5.4e-53 yusN M Coat F domain
HKKKDAFM_03313 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
HKKKDAFM_03314 8.5e-293 yusP P Major facilitator superfamily
HKKKDAFM_03315 2.7e-64 yusQ S Tautomerase enzyme
HKKKDAFM_03316 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03317 5.7e-158 yusT K LysR substrate binding domain
HKKKDAFM_03318 3.8e-47 yusU S Protein of unknown function (DUF2573)
HKKKDAFM_03319 1e-153 yusV 3.6.3.34 HP ABC transporter
HKKKDAFM_03320 2.5e-66 S YusW-like protein
HKKKDAFM_03321 7.9e-300 pepF2 E COG1164 Oligoendopeptidase F
HKKKDAFM_03322 2.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03323 1.2e-79 dps P Ferritin-like domain
HKKKDAFM_03324 1.2e-231 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKKDAFM_03325 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_03326 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HKKKDAFM_03327 1.3e-157 yuxN K Transcriptional regulator
HKKKDAFM_03328 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HKKKDAFM_03329 2.3e-24 S Protein of unknown function (DUF3970)
HKKKDAFM_03330 1.4e-246 gerAA EG Spore germination protein
HKKKDAFM_03331 9.1e-198 gerAB E Spore germination protein
HKKKDAFM_03332 3.3e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
HKKKDAFM_03333 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_03334 3.5e-186 vraS 2.7.13.3 T Histidine kinase
HKKKDAFM_03335 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HKKKDAFM_03336 2.3e-127 liaG S Putative adhesin
HKKKDAFM_03337 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HKKKDAFM_03338 5.6e-62 liaI S membrane
HKKKDAFM_03339 1.4e-226 yvqJ EGP Major facilitator Superfamily
HKKKDAFM_03340 1.4e-101 yvqK 2.5.1.17 S Adenosyltransferase
HKKKDAFM_03341 1.1e-242 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HKKKDAFM_03342 1.6e-183 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_03343 1.9e-167 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HKKKDAFM_03344 2.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03345 2.9e-170 yvrE G SMP-30/Gluconolaconase/LRE-like region
HKKKDAFM_03346 0.0 T PhoQ Sensor
HKKKDAFM_03347 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_03348 3.6e-22
HKKKDAFM_03349 9.5e-98 yvrI K RNA polymerase
HKKKDAFM_03350 2.4e-19 S YvrJ protein family
HKKKDAFM_03351 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
HKKKDAFM_03352 3.8e-64 yvrL S Regulatory protein YrvL
HKKKDAFM_03353 7.5e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HKKKDAFM_03354 2.1e-123 macB V ABC transporter, ATP-binding protein
HKKKDAFM_03355 2.6e-174 M Efflux transporter rnd family, mfp subunit
HKKKDAFM_03356 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HKKKDAFM_03357 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_03358 4.6e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HKKKDAFM_03359 7.6e-177 fhuD P ABC transporter
HKKKDAFM_03361 4.9e-236 yvsH E Arginine ornithine antiporter
HKKKDAFM_03362 6.5e-16 S Small spore protein J (Spore_SspJ)
HKKKDAFM_03363 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HKKKDAFM_03364 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HKKKDAFM_03365 1.3e-168 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HKKKDAFM_03366 3e-134 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HKKKDAFM_03367 4e-119 modB P COG4149 ABC-type molybdate transport system, permease component
HKKKDAFM_03368 4.2e-155 yvgN S reductase
HKKKDAFM_03369 2.1e-85 yvgO
HKKKDAFM_03370 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HKKKDAFM_03371 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HKKKDAFM_03372 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HKKKDAFM_03373 0.0 helD 3.6.4.12 L DNA helicase
HKKKDAFM_03374 4.1e-107 yvgT S membrane
HKKKDAFM_03375 7.2e-71 bdbC O Required for disulfide bond formation in some proteins
HKKKDAFM_03376 2.7e-104 bdbD O Thioredoxin
HKKKDAFM_03377 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HKKKDAFM_03378 0.0 copA 3.6.3.54 P P-type ATPase
HKKKDAFM_03379 1.5e-29 copZ P Copper resistance protein CopZ
HKKKDAFM_03380 2.2e-48 csoR S transcriptional
HKKKDAFM_03381 3.1e-195 yvaA 1.1.1.371 S Oxidoreductase
HKKKDAFM_03382 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HKKKDAFM_03383 0.0 yvaC S Fusaric acid resistance protein-like
HKKKDAFM_03384 1.3e-72 yvaD S Family of unknown function (DUF5360)
HKKKDAFM_03385 6.9e-54 yvaE P Small Multidrug Resistance protein
HKKKDAFM_03386 4.1e-101 K Bacterial regulatory proteins, tetR family
HKKKDAFM_03387 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03389 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HKKKDAFM_03390 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HKKKDAFM_03391 5.6e-143 est 3.1.1.1 S Carboxylesterase
HKKKDAFM_03392 2.4e-23 secG U Preprotein translocase subunit SecG
HKKKDAFM_03393 3.7e-153 yvaM S Serine aminopeptidase, S33
HKKKDAFM_03394 7.5e-36 yvzC K Transcriptional
HKKKDAFM_03395 4e-69 K transcriptional
HKKKDAFM_03396 9.8e-68 yvaO K Cro/C1-type HTH DNA-binding domain
HKKKDAFM_03397 2.2e-54 yodB K transcriptional
HKKKDAFM_03398 1.1e-213 NT chemotaxis protein
HKKKDAFM_03399 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKKDAFM_03400 8e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKKKDAFM_03401 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKKDAFM_03402 2.8e-210 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKKKDAFM_03403 3.3e-60 yvbF K Belongs to the GbsR family
HKKKDAFM_03404 1.9e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKKDAFM_03405 9.4e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HKKKDAFM_03406 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HKKKDAFM_03407 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HKKKDAFM_03408 3.5e-97 yvbF K Belongs to the GbsR family
HKKKDAFM_03409 2.7e-101 yvbG U UPF0056 membrane protein
HKKKDAFM_03410 8.6e-113 yvbH S YvbH-like oligomerisation region
HKKKDAFM_03411 1.3e-120 exoY M Membrane
HKKKDAFM_03412 0.0 tcaA S response to antibiotic
HKKKDAFM_03413 3.1e-75 yvbK 3.1.3.25 K acetyltransferase
HKKKDAFM_03414 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HKKKDAFM_03415 3.7e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HKKKDAFM_03416 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HKKKDAFM_03417 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HKKKDAFM_03418 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HKKKDAFM_03419 2.6e-183 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKKKDAFM_03420 1.6e-252 araE EGP Major facilitator Superfamily
HKKKDAFM_03421 2.1e-202 araR K transcriptional
HKKKDAFM_03422 1.7e-190 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_03423 5.1e-159 yvbU K Transcriptional regulator
HKKKDAFM_03424 7.2e-156 yvbV EG EamA-like transporter family
HKKKDAFM_03425 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HKKKDAFM_03426 6.8e-195 yvbX S Glycosyl hydrolase
HKKKDAFM_03427 1.2e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKKKDAFM_03428 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HKKKDAFM_03429 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HKKKDAFM_03430 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_03431 1.6e-194 desK 2.7.13.3 T Histidine kinase
HKKKDAFM_03432 6.9e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
HKKKDAFM_03433 1.7e-157 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HKKKDAFM_03434 6.4e-156 rsbQ S Alpha/beta hydrolase family
HKKKDAFM_03435 3.2e-196 rsbU 3.1.3.3 T response regulator
HKKKDAFM_03436 2.3e-248 galA 3.2.1.89 G arabinogalactan
HKKKDAFM_03437 0.0 lacA 3.2.1.23 G beta-galactosidase
HKKKDAFM_03438 7.2e-150 ganQ P transport
HKKKDAFM_03439 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HKKKDAFM_03440 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
HKKKDAFM_03441 2e-183 lacR K Transcriptional regulator
HKKKDAFM_03442 2.3e-112 yvfI K COG2186 Transcriptional regulators
HKKKDAFM_03443 3.3e-308 yvfH C L-lactate permease
HKKKDAFM_03444 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HKKKDAFM_03445 1e-31 yvfG S YvfG protein
HKKKDAFM_03446 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
HKKKDAFM_03447 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HKKKDAFM_03448 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HKKKDAFM_03449 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKKKDAFM_03450 1.4e-257 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_03451 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKKDAFM_03452 1.2e-202 epsI GM pyruvyl transferase
HKKKDAFM_03453 2e-194 epsH GT2 S Glycosyltransferase like family 2
HKKKDAFM_03454 7e-206 epsG S EpsG family
HKKKDAFM_03455 6.4e-218 epsF GT4 M Glycosyl transferases group 1
HKKKDAFM_03456 1.2e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HKKKDAFM_03457 1.2e-221 epsD GT4 M Glycosyl transferase 4-like
HKKKDAFM_03458 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HKKKDAFM_03459 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HKKKDAFM_03460 4e-122 ywqC M biosynthesis protein
HKKKDAFM_03461 1.4e-75 slr K transcriptional
HKKKDAFM_03462 1.6e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HKKKDAFM_03464 5.1e-92 padC Q Phenolic acid decarboxylase
HKKKDAFM_03465 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
HKKKDAFM_03466 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HKKKDAFM_03467 3.2e-261 pbpE V Beta-lactamase
HKKKDAFM_03468 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HKKKDAFM_03469 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HKKKDAFM_03470 3.9e-295 yveA E amino acid
HKKKDAFM_03471 2.6e-106 yvdT K Transcriptional regulator
HKKKDAFM_03472 1.9e-50 ykkC P Small Multidrug Resistance protein
HKKKDAFM_03473 4.1e-50 sugE P Small Multidrug Resistance protein
HKKKDAFM_03474 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HKKKDAFM_03475 1.1e-269 ygaK C COG0277 FAD FMN-containing dehydrogenases
HKKKDAFM_03476 2.8e-182 S Patatin-like phospholipase
HKKKDAFM_03478 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HKKKDAFM_03479 2.8e-117 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HKKKDAFM_03480 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HKKKDAFM_03481 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HKKKDAFM_03482 1.1e-156 malA S Protein of unknown function (DUF1189)
HKKKDAFM_03483 3.9e-148 malD P transport
HKKKDAFM_03484 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
HKKKDAFM_03485 2e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HKKKDAFM_03486 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HKKKDAFM_03487 1.5e-172 yvdE K Transcriptional regulator
HKKKDAFM_03488 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HKKKDAFM_03489 1.5e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HKKKDAFM_03490 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HKKKDAFM_03491 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HKKKDAFM_03492 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HKKKDAFM_03493 0.0 yxdM V ABC transporter (permease)
HKKKDAFM_03494 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HKKKDAFM_03495 1.2e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HKKKDAFM_03496 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_03497 1.8e-33
HKKKDAFM_03498 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HKKKDAFM_03499 1.6e-36 crh G Phosphocarrier protein Chr
HKKKDAFM_03500 1.4e-170 whiA K May be required for sporulation
HKKKDAFM_03501 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HKKKDAFM_03502 5.7e-166 rapZ S Displays ATPase and GTPase activities
HKKKDAFM_03503 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HKKKDAFM_03504 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HKKKDAFM_03505 1.4e-102 usp CBM50 M protein conserved in bacteria
HKKKDAFM_03506 2.4e-278 S COG0457 FOG TPR repeat
HKKKDAFM_03507 0.0 msbA2 3.6.3.44 V ABC transporter
HKKKDAFM_03509 1e-252
HKKKDAFM_03510 2.1e-70
HKKKDAFM_03511 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HKKKDAFM_03512 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HKKKDAFM_03513 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HKKKDAFM_03514 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HKKKDAFM_03515 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HKKKDAFM_03516 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HKKKDAFM_03517 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HKKKDAFM_03518 1.5e-219 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HKKKDAFM_03519 3.8e-139 yvpB NU protein conserved in bacteria
HKKKDAFM_03520 5.1e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HKKKDAFM_03521 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HKKKDAFM_03522 1.1e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HKKKDAFM_03523 1.1e-162 yvoD P COG0370 Fe2 transport system protein B
HKKKDAFM_03524 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HKKKDAFM_03525 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HKKKDAFM_03526 2.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HKKKDAFM_03527 4.3e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HKKKDAFM_03528 1.8e-133 yvoA K transcriptional
HKKKDAFM_03529 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HKKKDAFM_03530 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_03531 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HKKKDAFM_03532 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HKKKDAFM_03533 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_03534 6.1e-203 yvmA EGP Major facilitator Superfamily
HKKKDAFM_03535 1.2e-50 yvlD S Membrane
HKKKDAFM_03536 2.6e-26 pspB KT PspC domain
HKKKDAFM_03537 7.5e-168 yvlB S Putative adhesin
HKKKDAFM_03538 8e-49 yvlA
HKKKDAFM_03539 6.7e-34 yvkN
HKKKDAFM_03540 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKKKDAFM_03541 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HKKKDAFM_03542 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HKKKDAFM_03543 1.2e-30 csbA S protein conserved in bacteria
HKKKDAFM_03544 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HKKKDAFM_03545 7e-101 yvkB K Transcriptional regulator
HKKKDAFM_03546 7.9e-228 yvkA EGP Major facilitator Superfamily
HKKKDAFM_03547 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKKDAFM_03548 5.3e-56 swrA S Swarming motility protein
HKKKDAFM_03549 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HKKKDAFM_03550 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HKKKDAFM_03551 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HKKKDAFM_03552 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HKKKDAFM_03553 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HKKKDAFM_03554 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HKKKDAFM_03555 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HKKKDAFM_03556 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HKKKDAFM_03557 2.8e-66
HKKKDAFM_03558 1.9e-08 fliT S bacterial-type flagellum organization
HKKKDAFM_03559 2.9e-69 fliS N flagellar protein FliS
HKKKDAFM_03560 1.1e-265 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HKKKDAFM_03561 6.1e-57 flaG N flagellar protein FlaG
HKKKDAFM_03562 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HKKKDAFM_03563 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HKKKDAFM_03564 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HKKKDAFM_03565 2.6e-50 yviE
HKKKDAFM_03566 1.1e-156 flgL N Belongs to the bacterial flagellin family
HKKKDAFM_03567 1.2e-264 flgK N flagellar hook-associated protein
HKKKDAFM_03568 2.4e-78 flgN NOU FlgN protein
HKKKDAFM_03569 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HKKKDAFM_03570 7e-74 yvyF S flagellar protein
HKKKDAFM_03571 2.7e-129 comFC S Phosphoribosyl transferase domain
HKKKDAFM_03572 5.7e-46 comFB S Late competence development protein ComFB
HKKKDAFM_03573 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HKKKDAFM_03574 7.3e-155 degV S protein conserved in bacteria
HKKKDAFM_03575 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HKKKDAFM_03576 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HKKKDAFM_03577 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HKKKDAFM_03578 6e-163 yvhJ K Transcriptional regulator
HKKKDAFM_03579 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HKKKDAFM_03580 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HKKKDAFM_03581 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HKKKDAFM_03582 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HKKKDAFM_03583 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HKKKDAFM_03584 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKKDAFM_03585 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HKKKDAFM_03586 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HKKKDAFM_03587 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HKKKDAFM_03588 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HKKKDAFM_03589 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HKKKDAFM_03590 6e-38
HKKKDAFM_03591 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HKKKDAFM_03592 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HKKKDAFM_03593 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKKDAFM_03594 6.5e-57
HKKKDAFM_03595 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HKKKDAFM_03596 7.5e-93 ggaA M Glycosyltransferase like family 2
HKKKDAFM_03597 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKKKDAFM_03598 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKKDAFM_03599 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HKKKDAFM_03600 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HKKKDAFM_03601 4.1e-150 tagG GM Transport permease protein
HKKKDAFM_03602 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKKKDAFM_03603 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HKKKDAFM_03604 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HKKKDAFM_03605 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HKKKDAFM_03606 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HKKKDAFM_03607 3.5e-260
HKKKDAFM_03608 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HKKKDAFM_03609 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HKKKDAFM_03610 1.2e-261 gerBA EG Spore germination protein
HKKKDAFM_03611 1.5e-192 gerBB E Spore germination protein
HKKKDAFM_03612 3.2e-206 gerAC S Spore germination protein
HKKKDAFM_03613 1.9e-248 ywtG EGP Major facilitator Superfamily
HKKKDAFM_03614 8.4e-171 ywtF K Transcriptional regulator
HKKKDAFM_03615 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HKKKDAFM_03616 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HKKKDAFM_03617 3.6e-21 ywtC
HKKKDAFM_03618 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HKKKDAFM_03619 8.6e-70 pgsC S biosynthesis protein
HKKKDAFM_03620 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HKKKDAFM_03621 9.3e-178 rbsR K transcriptional
HKKKDAFM_03622 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HKKKDAFM_03623 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HKKKDAFM_03624 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HKKKDAFM_03625 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
HKKKDAFM_03626 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HKKKDAFM_03627 8.7e-93 batE T Sh3 type 3 domain protein
HKKKDAFM_03628 8e-48 ywsA S Protein of unknown function (DUF3892)
HKKKDAFM_03629 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HKKKDAFM_03630 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HKKKDAFM_03631 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HKKKDAFM_03632 1.1e-169 alsR K LysR substrate binding domain
HKKKDAFM_03633 5.5e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HKKKDAFM_03634 3.1e-124 ywrJ
HKKKDAFM_03635 8.2e-131 cotB
HKKKDAFM_03636 3.5e-210 cotH M Spore Coat
HKKKDAFM_03637 3.7e-12
HKKKDAFM_03638 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HKKKDAFM_03639 1.4e-53 S Domain of unknown function (DUF4181)
HKKKDAFM_03640 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HKKKDAFM_03641 8e-82 ywrC K Transcriptional regulator
HKKKDAFM_03642 1.2e-103 ywrB P Chromate transporter
HKKKDAFM_03643 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
HKKKDAFM_03645 1.1e-100 ywqN S NAD(P)H-dependent
HKKKDAFM_03646 1.4e-161 K Transcriptional regulator
HKKKDAFM_03647 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HKKKDAFM_03648 3.9e-25
HKKKDAFM_03649 1.9e-82 ywqJ S Pre-toxin TG
HKKKDAFM_03650 5.2e-17
HKKKDAFM_03651 7.9e-43
HKKKDAFM_03652 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
HKKKDAFM_03653 8.6e-38 ywqI S Family of unknown function (DUF5344)
HKKKDAFM_03654 9.7e-23 S Domain of unknown function (DUF5082)
HKKKDAFM_03655 1.4e-152 ywqG S Domain of unknown function (DUF1963)
HKKKDAFM_03656 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HKKKDAFM_03657 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HKKKDAFM_03658 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HKKKDAFM_03659 2e-116 ywqC M biosynthesis protein
HKKKDAFM_03660 1.2e-17
HKKKDAFM_03661 1.4e-308 ywqB S SWIM zinc finger
HKKKDAFM_03662 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HKKKDAFM_03663 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HKKKDAFM_03664 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HKKKDAFM_03665 3.7e-57 ssbB L Single-stranded DNA-binding protein
HKKKDAFM_03666 3.8e-66 ywpG
HKKKDAFM_03667 1.1e-66 ywpF S YwpF-like protein
HKKKDAFM_03668 1.2e-49 srtA 3.4.22.70 M Sortase family
HKKKDAFM_03669 7e-153 ywpD T Histidine kinase
HKKKDAFM_03670 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HKKKDAFM_03671 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HKKKDAFM_03672 8.8e-198 S aspartate phosphatase
HKKKDAFM_03673 3.7e-140 flhP N flagellar basal body
HKKKDAFM_03674 9.9e-125 flhO N flagellar basal body
HKKKDAFM_03675 3.5e-180 mbl D Rod shape-determining protein
HKKKDAFM_03676 3e-44 spoIIID K Stage III sporulation protein D
HKKKDAFM_03677 2.1e-70 ywoH K COG1846 Transcriptional regulators
HKKKDAFM_03678 3.9e-210 ywoG EGP Major facilitator Superfamily
HKKKDAFM_03679 2.8e-231 ywoF P Right handed beta helix region
HKKKDAFM_03680 6.8e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HKKKDAFM_03681 9.8e-242 ywoD EGP Major facilitator superfamily
HKKKDAFM_03682 4e-104 phzA Q Isochorismatase family
HKKKDAFM_03683 4.1e-75
HKKKDAFM_03684 2.5e-225 amt P Ammonium transporter
HKKKDAFM_03685 1.6e-58 nrgB K Belongs to the P(II) protein family
HKKKDAFM_03686 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HKKKDAFM_03687 3e-72 ywnJ S VanZ like family
HKKKDAFM_03688 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HKKKDAFM_03689 4.1e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HKKKDAFM_03690 8.9e-10 ywnC S Family of unknown function (DUF5362)
HKKKDAFM_03691 2.2e-70 ywnF S Family of unknown function (DUF5392)
HKKKDAFM_03692 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKKKDAFM_03693 5e-142 mta K transcriptional
HKKKDAFM_03694 2.6e-59 ywnC S Family of unknown function (DUF5362)
HKKKDAFM_03695 1.6e-114 ywnB S NAD(P)H-binding
HKKKDAFM_03696 1.7e-64 ywnA K Transcriptional regulator
HKKKDAFM_03697 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HKKKDAFM_03698 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HKKKDAFM_03699 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HKKKDAFM_03701 3.8e-11 csbD K CsbD-like
HKKKDAFM_03702 3e-84 ywmF S Peptidase M50
HKKKDAFM_03703 1.3e-103 S response regulator aspartate phosphatase
HKKKDAFM_03704 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HKKKDAFM_03705 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HKKKDAFM_03707 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HKKKDAFM_03708 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HKKKDAFM_03709 1e-174 spoIID D Stage II sporulation protein D
HKKKDAFM_03710 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKKKDAFM_03711 1.6e-134 ywmB S TATA-box binding
HKKKDAFM_03712 1.3e-32 ywzB S membrane
HKKKDAFM_03713 1.3e-60 ywmA
HKKKDAFM_03714 1.4e-13 ywmA
HKKKDAFM_03715 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HKKKDAFM_03716 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HKKKDAFM_03717 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HKKKDAFM_03718 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HKKKDAFM_03719 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKKKDAFM_03720 6.4e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HKKKDAFM_03721 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HKKKDAFM_03722 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HKKKDAFM_03723 2.5e-62 atpI S ATP synthase
HKKKDAFM_03724 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HKKKDAFM_03725 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HKKKDAFM_03726 7.2e-95 ywlG S Belongs to the UPF0340 family
HKKKDAFM_03727 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HKKKDAFM_03728 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HKKKDAFM_03729 1.7e-91 mntP P Probably functions as a manganese efflux pump
HKKKDAFM_03730 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HKKKDAFM_03731 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HKKKDAFM_03732 3e-111 spoIIR S stage II sporulation protein R
HKKKDAFM_03733 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
HKKKDAFM_03735 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HKKKDAFM_03736 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HKKKDAFM_03737 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_03738 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HKKKDAFM_03739 8.6e-160 ywkB S Membrane transport protein
HKKKDAFM_03740 0.0 sfcA 1.1.1.38 C malic enzyme
HKKKDAFM_03741 1.6e-103 tdk 2.7.1.21 F thymidine kinase
HKKKDAFM_03742 1.1e-32 rpmE J Binds the 23S rRNA
HKKKDAFM_03743 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HKKKDAFM_03744 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HKKKDAFM_03745 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HKKKDAFM_03746 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HKKKDAFM_03747 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HKKKDAFM_03748 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HKKKDAFM_03749 5.1e-90 ywjG S Domain of unknown function (DUF2529)
HKKKDAFM_03750 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HKKKDAFM_03751 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HKKKDAFM_03752 1.3e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HKKKDAFM_03753 0.0 fadF C COG0247 Fe-S oxidoreductase
HKKKDAFM_03754 1.5e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HKKKDAFM_03755 3.3e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HKKKDAFM_03756 2.7e-42 ywjC
HKKKDAFM_03757 4.8e-96 ywjB H RibD C-terminal domain
HKKKDAFM_03758 0.0 ywjA V ABC transporter
HKKKDAFM_03759 2.4e-286 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HKKKDAFM_03760 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
HKKKDAFM_03761 1.1e-93 narJ 1.7.5.1 C nitrate reductase
HKKKDAFM_03762 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
HKKKDAFM_03763 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKKDAFM_03764 7e-86 arfM T cyclic nucleotide binding
HKKKDAFM_03765 1.7e-139 ywiC S YwiC-like protein
HKKKDAFM_03766 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
HKKKDAFM_03767 2.3e-213 narK P COG2223 Nitrate nitrite transporter
HKKKDAFM_03768 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HKKKDAFM_03769 4.7e-73 ywiB S protein conserved in bacteria
HKKKDAFM_03770 1e-07 S Bacteriocin subtilosin A
HKKKDAFM_03771 5.4e-269 C Fe-S oxidoreductases
HKKKDAFM_03773 3.3e-132 cbiO V ABC transporter
HKKKDAFM_03774 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HKKKDAFM_03775 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
HKKKDAFM_03776 1.6e-249 L Peptidase, M16
HKKKDAFM_03778 4.7e-244 ywhL CO amine dehydrogenase activity
HKKKDAFM_03779 2.3e-198 ywhK CO amine dehydrogenase activity
HKKKDAFM_03780 3.1e-79 S aspartate phosphatase
HKKKDAFM_03782 1.6e-26 ywhH S Aminoacyl-tRNA editing domain
HKKKDAFM_03783 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HKKKDAFM_03784 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HKKKDAFM_03785 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HKKKDAFM_03786 3.6e-49
HKKKDAFM_03787 5.2e-95 ywhD S YwhD family
HKKKDAFM_03788 5.1e-119 ywhC S Peptidase family M50
HKKKDAFM_03789 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HKKKDAFM_03790 9.5e-71 ywhA K Transcriptional regulator
HKKKDAFM_03791 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HKKKDAFM_03793 1.3e-236 mmr U Major Facilitator Superfamily
HKKKDAFM_03794 6.2e-79 yffB K Transcriptional regulator
HKKKDAFM_03795 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HKKKDAFM_03796 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
HKKKDAFM_03797 3.1e-36 ywzC S Belongs to the UPF0741 family
HKKKDAFM_03798 1.6e-111 rsfA_1
HKKKDAFM_03799 2.2e-157 ywfM EG EamA-like transporter family
HKKKDAFM_03800 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HKKKDAFM_03801 1.1e-156 cysL K Transcriptional regulator
HKKKDAFM_03802 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HKKKDAFM_03803 1.1e-146 ywfI C May function as heme-dependent peroxidase
HKKKDAFM_03804 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_03805 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
HKKKDAFM_03806 1.9e-209 bacE EGP Major facilitator Superfamily
HKKKDAFM_03807 6.8e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HKKKDAFM_03808 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HKKKDAFM_03809 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HKKKDAFM_03810 9.5e-112 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HKKKDAFM_03811 6e-206 ywfA EGP Major facilitator Superfamily
HKKKDAFM_03812 4.8e-249 lysP E amino acid
HKKKDAFM_03813 0.0 rocB E arginine degradation protein
HKKKDAFM_03814 1.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HKKKDAFM_03815 2.8e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HKKKDAFM_03816 4.4e-77
HKKKDAFM_03817 3.5e-87 spsL 5.1.3.13 M Spore Coat
HKKKDAFM_03818 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HKKKDAFM_03819 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HKKKDAFM_03820 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HKKKDAFM_03821 1.5e-183 spsG M Spore Coat
HKKKDAFM_03822 1e-128 spsF M Spore Coat
HKKKDAFM_03823 7.1e-214 spsE 2.5.1.56 M acid synthase
HKKKDAFM_03824 1.7e-162 spsD 2.3.1.210 K Spore Coat
HKKKDAFM_03825 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HKKKDAFM_03826 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
HKKKDAFM_03827 2.8e-145 spsA M Spore Coat
HKKKDAFM_03828 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HKKKDAFM_03829 4.3e-59 ywdK S small membrane protein
HKKKDAFM_03830 3.7e-238 ywdJ F Xanthine uracil
HKKKDAFM_03831 6.6e-48 ywdI S Family of unknown function (DUF5327)
HKKKDAFM_03832 1e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKKKDAFM_03833 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HKKKDAFM_03834 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HKKKDAFM_03835 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HKKKDAFM_03836 2e-28 ywdA
HKKKDAFM_03837 7.5e-293 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HKKKDAFM_03838 7.3e-253 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_03839 5.7e-138 focA P Formate/nitrite transporter
HKKKDAFM_03840 7e-150 sacT K transcriptional antiterminator
HKKKDAFM_03842 0.0 vpr O Belongs to the peptidase S8 family
HKKKDAFM_03843 3.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_03844 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HKKKDAFM_03845 8.6e-202 rodA D Belongs to the SEDS family
HKKKDAFM_03846 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HKKKDAFM_03847 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKKKDAFM_03848 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HKKKDAFM_03849 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HKKKDAFM_03850 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HKKKDAFM_03851 1e-35 ywzA S membrane
HKKKDAFM_03852 2.6e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HKKKDAFM_03853 1.9e-225 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HKKKDAFM_03854 9.5e-60 gtcA S GtrA-like protein
HKKKDAFM_03855 1.1e-121 ywcC K transcriptional regulator
HKKKDAFM_03857 9.8e-49 ywcB S Protein of unknown function, DUF485
HKKKDAFM_03858 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HKKKDAFM_03859 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HKKKDAFM_03860 3.2e-223 ywbN P Dyp-type peroxidase family protein
HKKKDAFM_03861 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
HKKKDAFM_03862 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
HKKKDAFM_03863 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HKKKDAFM_03864 1.4e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HKKKDAFM_03865 4.3e-153 ywbI K Transcriptional regulator
HKKKDAFM_03866 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HKKKDAFM_03867 2.3e-111 ywbG M effector of murein hydrolase
HKKKDAFM_03868 8.1e-208 ywbF EGP Major facilitator Superfamily
HKKKDAFM_03869 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
HKKKDAFM_03870 3.5e-219 ywbD 2.1.1.191 J Methyltransferase
HKKKDAFM_03871 9.9e-67 ywbC 4.4.1.5 E glyoxalase
HKKKDAFM_03872 6.9e-96 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
HKKKDAFM_03873 8.3e-125 ywbB S Protein of unknown function (DUF2711)
HKKKDAFM_03874 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKKDAFM_03875 2.9e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
HKKKDAFM_03876 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_03877 7.6e-152 sacY K transcriptional antiterminator
HKKKDAFM_03878 4.5e-168 gspA M General stress
HKKKDAFM_03879 1.5e-124 ywaF S Integral membrane protein
HKKKDAFM_03880 1.2e-86 ywaE K Transcriptional regulator
HKKKDAFM_03881 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HKKKDAFM_03882 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HKKKDAFM_03883 4e-92 K Helix-turn-helix XRE-family like proteins
HKKKDAFM_03884 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
HKKKDAFM_03885 8.8e-130 ynfM EGP Major facilitator Superfamily
HKKKDAFM_03886 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HKKKDAFM_03887 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HKKKDAFM_03888 5e-14 S D-Ala-teichoic acid biosynthesis protein
HKKKDAFM_03889 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_03890 3.6e-232 dltB M membrane protein involved in D-alanine export
HKKKDAFM_03891 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HKKKDAFM_03892 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HKKKDAFM_03893 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_03894 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HKKKDAFM_03895 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HKKKDAFM_03896 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HKKKDAFM_03897 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HKKKDAFM_03898 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HKKKDAFM_03899 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HKKKDAFM_03900 1.1e-19 yxzF
HKKKDAFM_03901 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HKKKDAFM_03902 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKKDAFM_03903 1.6e-211 yxlH EGP Major facilitator Superfamily
HKKKDAFM_03904 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HKKKDAFM_03905 8.2e-165 yxlF V ABC transporter, ATP-binding protein
HKKKDAFM_03906 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HKKKDAFM_03907 1.4e-30
HKKKDAFM_03908 1.6e-46 yxlC S Family of unknown function (DUF5345)
HKKKDAFM_03909 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HKKKDAFM_03910 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HKKKDAFM_03911 3.5e-157 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HKKKDAFM_03912 0.0 cydD V ATP-binding protein
HKKKDAFM_03913 4e-309 cydD V ATP-binding
HKKKDAFM_03914 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HKKKDAFM_03915 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
HKKKDAFM_03916 1.5e-229 cimH C COG3493 Na citrate symporter
HKKKDAFM_03917 9.4e-311 3.4.24.84 O Peptidase family M48
HKKKDAFM_03919 9.9e-152 yxkH G Polysaccharide deacetylase
HKKKDAFM_03920 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HKKKDAFM_03921 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
HKKKDAFM_03922 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKKDAFM_03923 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HKKKDAFM_03924 1.4e-73 yxkC S Domain of unknown function (DUF4352)
HKKKDAFM_03925 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HKKKDAFM_03926 7.7e-77 S Protein of unknown function (DUF1453)
HKKKDAFM_03927 1.6e-190 yxjM T Signal transduction histidine kinase
HKKKDAFM_03928 9.8e-115 K helix_turn_helix, Lux Regulon
HKKKDAFM_03929 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HKKKDAFM_03931 1.4e-86 yxjI S LURP-one-related
HKKKDAFM_03932 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HKKKDAFM_03933 1e-220 yxjG 2.1.1.14 E Methionine synthase
HKKKDAFM_03934 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HKKKDAFM_03935 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HKKKDAFM_03936 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HKKKDAFM_03937 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HKKKDAFM_03938 5.5e-158 rlmA 2.1.1.187 Q Methyltransferase domain
HKKKDAFM_03939 5.4e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKKDAFM_03940 1.5e-102 T Domain of unknown function (DUF4163)
HKKKDAFM_03941 3e-47 yxiS
HKKKDAFM_03942 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HKKKDAFM_03943 6.6e-224 citH C Citrate transporter
HKKKDAFM_03944 3.6e-142 exoK GH16 M licheninase activity
HKKKDAFM_03945 8.3e-151 licT K transcriptional antiterminator
HKKKDAFM_03946 2e-110
HKKKDAFM_03947 5.6e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
HKKKDAFM_03948 5.6e-264 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HKKKDAFM_03949 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HKKKDAFM_03952 1.6e-48 yxiJ S YxiJ-like protein
HKKKDAFM_03953 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HKKKDAFM_03954 3.8e-81
HKKKDAFM_03955 4.9e-46
HKKKDAFM_03956 3.7e-75 yxiG
HKKKDAFM_03957 6.4e-63
HKKKDAFM_03958 1.7e-84
HKKKDAFM_03959 1.5e-71 yxxG
HKKKDAFM_03960 0.0 wapA M COG3209 Rhs family protein
HKKKDAFM_03961 2.9e-168 yxxF EG EamA-like transporter family
HKKKDAFM_03962 1.1e-72 yxiE T Belongs to the universal stress protein A family
HKKKDAFM_03963 6.2e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKKDAFM_03964 4.3e-309 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HKKKDAFM_03965 3.6e-51
HKKKDAFM_03966 2.2e-78 S SMI1 / KNR4 family
HKKKDAFM_03967 0.0 S nuclease activity
HKKKDAFM_03968 3.6e-39 yxiC S Family of unknown function (DUF5344)
HKKKDAFM_03969 2.1e-21 S Domain of unknown function (DUF5082)
HKKKDAFM_03970 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HKKKDAFM_03971 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HKKKDAFM_03972 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HKKKDAFM_03973 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HKKKDAFM_03974 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HKKKDAFM_03975 6.8e-181 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HKKKDAFM_03976 1.3e-249 lysP E amino acid
HKKKDAFM_03977 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HKKKDAFM_03978 8.3e-205 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HKKKDAFM_03979 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HKKKDAFM_03980 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HKKKDAFM_03981 1.3e-151 yxxB S Domain of Unknown Function (DUF1206)
HKKKDAFM_03982 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HKKKDAFM_03983 2e-255 yxeQ S MmgE/PrpD family
HKKKDAFM_03984 1.4e-212 yxeP 3.5.1.47 E hydrolase activity
HKKKDAFM_03985 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HKKKDAFM_03986 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
HKKKDAFM_03987 3.6e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
HKKKDAFM_03988 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HKKKDAFM_03989 3.1e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HKKKDAFM_03991 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HKKKDAFM_03992 6.2e-151 yidA S hydrolases of the HAD superfamily
HKKKDAFM_03995 1.3e-20 yxeE
HKKKDAFM_03996 1.9e-16 yxeD
HKKKDAFM_03997 8.5e-69
HKKKDAFM_03998 5.1e-176 fhuD P ABC transporter
HKKKDAFM_03999 3.4e-58 yxeA S Protein of unknown function (DUF1093)
HKKKDAFM_04000 0.0 yxdM V ABC transporter (permease)
HKKKDAFM_04001 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HKKKDAFM_04002 6.9e-181 T PhoQ Sensor
HKKKDAFM_04003 2.1e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_04004 1.2e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HKKKDAFM_04005 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HKKKDAFM_04006 8.6e-167 iolH G Xylose isomerase-like TIM barrel
HKKKDAFM_04007 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HKKKDAFM_04008 5.1e-235 iolF EGP Major facilitator Superfamily
HKKKDAFM_04009 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HKKKDAFM_04010 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HKKKDAFM_04011 1.4e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HKKKDAFM_04012 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HKKKDAFM_04013 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HKKKDAFM_04014 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HKKKDAFM_04015 8.3e-176 iolS C Aldo keto reductase
HKKKDAFM_04017 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HKKKDAFM_04018 2.3e-246 csbC EGP Major facilitator Superfamily
HKKKDAFM_04019 0.0 htpG O Molecular chaperone. Has ATPase activity
HKKKDAFM_04021 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HKKKDAFM_04022 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HKKKDAFM_04023 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HKKKDAFM_04024 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HKKKDAFM_04025 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HKKKDAFM_04026 3.3e-127 yxbB Q Met-10+ like-protein
HKKKDAFM_04027 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HKKKDAFM_04028 1.1e-86 yxnB
HKKKDAFM_04029 0.0 asnB 6.3.5.4 E Asparagine synthase
HKKKDAFM_04030 7.6e-214 yxaM U MFS_1 like family
HKKKDAFM_04031 6.8e-93 S PQQ-like domain
HKKKDAFM_04032 3.5e-65 S Family of unknown function (DUF5391)
HKKKDAFM_04033 1.1e-75 yxaI S membrane protein domain
HKKKDAFM_04034 1.4e-228 P Protein of unknown function (DUF418)
HKKKDAFM_04035 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
HKKKDAFM_04036 1.2e-100 yxaF K Transcriptional regulator
HKKKDAFM_04037 1.9e-200 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HKKKDAFM_04038 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HKKKDAFM_04039 5.2e-50 S LrgA family
HKKKDAFM_04040 1.3e-117 yxaC M effector of murein hydrolase
HKKKDAFM_04041 1.7e-193 yxaB GM Polysaccharide pyruvyl transferase
HKKKDAFM_04042 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HKKKDAFM_04043 2.8e-126 gntR K transcriptional
HKKKDAFM_04044 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HKKKDAFM_04045 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
HKKKDAFM_04046 1.8e-270 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HKKKDAFM_04047 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HKKKDAFM_04048 1.9e-286 ahpF O Alkyl hydroperoxide reductase
HKKKDAFM_04049 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HKKKDAFM_04050 3.4e-27 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
HKKKDAFM_04051 1.9e-124 yydK K Transcriptional regulator
HKKKDAFM_04052 6.9e-114 S ABC-2 family transporter protein
HKKKDAFM_04053 1.6e-109 prrC P ABC transporter
HKKKDAFM_04054 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HKKKDAFM_04055 1.3e-202 S SIR2-like domain
HKKKDAFM_04056 1.1e-180 L DNA synthesis involved in DNA repair
HKKKDAFM_04057 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HKKKDAFM_04058 1.1e-09 S YyzF-like protein
HKKKDAFM_04059 1.3e-67
HKKKDAFM_04060 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HKKKDAFM_04062 1.7e-30 yycQ S Protein of unknown function (DUF2651)
HKKKDAFM_04063 5.4e-201 yycP
HKKKDAFM_04064 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HKKKDAFM_04065 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
HKKKDAFM_04066 1.1e-187 S aspartate phosphatase
HKKKDAFM_04068 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HKKKDAFM_04069 1.3e-260 rocE E amino acid
HKKKDAFM_04070 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HKKKDAFM_04071 7.4e-16
HKKKDAFM_04072 2.8e-94
HKKKDAFM_04073 2.3e-24 S Sporulation delaying protein SdpA
HKKKDAFM_04074 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HKKKDAFM_04075 1.5e-40 sdpR K transcriptional
HKKKDAFM_04076 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HKKKDAFM_04077 2.3e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
HKKKDAFM_04078 3.4e-94 K PFAM response regulator receiver
HKKKDAFM_04079 1.2e-73 S Peptidase propeptide and YPEB domain
HKKKDAFM_04080 3.8e-34 S Peptidase propeptide and YPEB domain
HKKKDAFM_04081 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HKKKDAFM_04082 4.3e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HKKKDAFM_04083 7.3e-155 yycI S protein conserved in bacteria
HKKKDAFM_04084 4.9e-257 yycH S protein conserved in bacteria
HKKKDAFM_04085 0.0 vicK 2.7.13.3 T Histidine kinase
HKKKDAFM_04086 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HKKKDAFM_04091 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HKKKDAFM_04092 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_04093 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HKKKDAFM_04094 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HKKKDAFM_04096 1.9e-15 yycC K YycC-like protein
HKKKDAFM_04097 8.4e-221 yeaN P COG2807 Cyanate permease
HKKKDAFM_04098 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HKKKDAFM_04099 2.2e-73 rplI J binds to the 23S rRNA
HKKKDAFM_04100 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HKKKDAFM_04101 8.3e-160 yybS S membrane
HKKKDAFM_04103 3.9e-84 cotF M Spore coat protein
HKKKDAFM_04104 1.7e-66 ydeP3 K Transcriptional regulator
HKKKDAFM_04105 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HKKKDAFM_04106 5.6e-61
HKKKDAFM_04108 3.9e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HKKKDAFM_04109 4.3e-111 K TipAS antibiotic-recognition domain
HKKKDAFM_04110 4.8e-124
HKKKDAFM_04111 2.9e-66 yybH S SnoaL-like domain
HKKKDAFM_04112 3.5e-54 yybG S Pentapeptide repeat-containing protein
HKKKDAFM_04113 4.3e-217 ynfM EGP Major facilitator Superfamily
HKKKDAFM_04114 4e-164 yybE K Transcriptional regulator
HKKKDAFM_04115 1.1e-77 yjcF S Acetyltransferase (GNAT) domain
HKKKDAFM_04116 2.3e-73 yybC
HKKKDAFM_04117 1.4e-124 S Metallo-beta-lactamase superfamily
HKKKDAFM_04118 5.6e-77 yybA 2.3.1.57 K transcriptional
HKKKDAFM_04119 2.4e-72 yjcF S Acetyltransferase (GNAT) domain
HKKKDAFM_04120 5.5e-96 yyaS S Membrane
HKKKDAFM_04121 3e-90 yyaR K Acetyltransferase (GNAT) domain
HKKKDAFM_04122 1.3e-65 yyaQ S YjbR
HKKKDAFM_04123 2.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
HKKKDAFM_04124 1.2e-244 tetL EGP Major facilitator Superfamily
HKKKDAFM_04125 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HKKKDAFM_04126 1.5e-60 yyaN K MerR HTH family regulatory protein
HKKKDAFM_04127 4.4e-161 yyaM EG EamA-like transporter family
HKKKDAFM_04128 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HKKKDAFM_04129 3.6e-168 yyaK S CAAX protease self-immunity
HKKKDAFM_04130 2.3e-243 EGP Major facilitator superfamily
HKKKDAFM_04131 1.1e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HKKKDAFM_04132 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HKKKDAFM_04133 8.9e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HKKKDAFM_04134 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
HKKKDAFM_04135 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HKKKDAFM_04136 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HKKKDAFM_04137 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HKKKDAFM_04138 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HKKKDAFM_04139 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HKKKDAFM_04140 2.3e-33 yyzM S protein conserved in bacteria
HKKKDAFM_04141 8.1e-177 yyaD S Membrane
HKKKDAFM_04142 1.6e-111 yyaC S Sporulation protein YyaC
HKKKDAFM_04143 2.1e-149 spo0J K Belongs to the ParB family
HKKKDAFM_04144 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HKKKDAFM_04145 9.6e-74 S Bacterial PH domain
HKKKDAFM_04146 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HKKKDAFM_04147 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HKKKDAFM_04148 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HKKKDAFM_04149 8.9e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HKKKDAFM_04150 6.5e-108 jag S single-stranded nucleic acid binding R3H
HKKKDAFM_04151 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HKKKDAFM_04152 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)