ORF_ID e_value Gene_name EC_number CAZy COGs Description
PPHEPGDA_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PPHEPGDA_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PPHEPGDA_00003 2.4e-33 yaaA S S4 domain
PPHEPGDA_00004 5.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PPHEPGDA_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
PPHEPGDA_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPHEPGDA_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PPHEPGDA_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00011 1.8e-181 yaaC S YaaC-like Protein
PPHEPGDA_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PPHEPGDA_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PPHEPGDA_00014 2.8e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PPHEPGDA_00015 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PPHEPGDA_00016 8.1e-206 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PPHEPGDA_00017 1.3e-09
PPHEPGDA_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
PPHEPGDA_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
PPHEPGDA_00020 1.2e-209 yaaH M Glycoside Hydrolase Family
PPHEPGDA_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
PPHEPGDA_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PPHEPGDA_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPHEPGDA_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PPHEPGDA_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PPHEPGDA_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
PPHEPGDA_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
PPHEPGDA_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
PPHEPGDA_00032 1.7e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PPHEPGDA_00033 6.4e-202 yaaN P Belongs to the TelA family
PPHEPGDA_00034 2.4e-270 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
PPHEPGDA_00035 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PPHEPGDA_00036 8.3e-54 yaaQ S protein conserved in bacteria
PPHEPGDA_00037 1.5e-71 yaaR S protein conserved in bacteria
PPHEPGDA_00038 3.5e-180 holB 2.7.7.7 L DNA polymerase III
PPHEPGDA_00039 2.3e-145 yaaT S stage 0 sporulation protein
PPHEPGDA_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
PPHEPGDA_00041 2.7e-137 yabB 2.1.1.223 S Conserved hypothetical protein 95
PPHEPGDA_00042 1.5e-49 yazA L endonuclease containing a URI domain
PPHEPGDA_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PPHEPGDA_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
PPHEPGDA_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PPHEPGDA_00046 2e-143 tatD L hydrolase, TatD
PPHEPGDA_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
PPHEPGDA_00048 9.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PPHEPGDA_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PPHEPGDA_00050 1.6e-136 yabG S peptidase
PPHEPGDA_00051 7.8e-39 veg S protein conserved in bacteria
PPHEPGDA_00052 8.3e-27 sspF S DNA topological change
PPHEPGDA_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PPHEPGDA_00054 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PPHEPGDA_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
PPHEPGDA_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
PPHEPGDA_00057 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PPHEPGDA_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PPHEPGDA_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PPHEPGDA_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PPHEPGDA_00061 2.4e-39 yabK S Peptide ABC transporter permease
PPHEPGDA_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PPHEPGDA_00063 1.5e-92 spoVT K stage V sporulation protein
PPHEPGDA_00064 3.2e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_00065 5.6e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
PPHEPGDA_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PPHEPGDA_00067 1.5e-49 yabP S Sporulation protein YabP
PPHEPGDA_00068 9.5e-107 yabQ S spore cortex biosynthesis protein
PPHEPGDA_00069 1.1e-44 divIC D Septum formation initiator
PPHEPGDA_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
PPHEPGDA_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
PPHEPGDA_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
PPHEPGDA_00075 1.3e-185 KLT serine threonine protein kinase
PPHEPGDA_00076 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PPHEPGDA_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PPHEPGDA_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PPHEPGDA_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PPHEPGDA_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PPHEPGDA_00081 8.9e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
PPHEPGDA_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPHEPGDA_00083 3.1e-267 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PPHEPGDA_00084 4.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
PPHEPGDA_00085 1.8e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
PPHEPGDA_00086 2.2e-159 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PPHEPGDA_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PPHEPGDA_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PPHEPGDA_00089 4.1e-30 yazB K transcriptional
PPHEPGDA_00090 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PPHEPGDA_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PPHEPGDA_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00097 2e-08
PPHEPGDA_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00103 2.9e-76 ctsR K Belongs to the CtsR family
PPHEPGDA_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
PPHEPGDA_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
PPHEPGDA_00106 0.0 clpC O Belongs to the ClpA ClpB family
PPHEPGDA_00107 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PPHEPGDA_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
PPHEPGDA_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
PPHEPGDA_00110 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PPHEPGDA_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PPHEPGDA_00112 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PPHEPGDA_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
PPHEPGDA_00114 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPHEPGDA_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PPHEPGDA_00116 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPHEPGDA_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
PPHEPGDA_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
PPHEPGDA_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PPHEPGDA_00120 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
PPHEPGDA_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PPHEPGDA_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PPHEPGDA_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PPHEPGDA_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PPHEPGDA_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
PPHEPGDA_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPHEPGDA_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPHEPGDA_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
PPHEPGDA_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PPHEPGDA_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PPHEPGDA_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PPHEPGDA_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PPHEPGDA_00133 3.1e-178 ybaC 3.4.11.5 S Alpha/beta hydrolase family
PPHEPGDA_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PPHEPGDA_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PPHEPGDA_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
PPHEPGDA_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PPHEPGDA_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PPHEPGDA_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PPHEPGDA_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PPHEPGDA_00141 6.8e-116 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PPHEPGDA_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PPHEPGDA_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
PPHEPGDA_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PPHEPGDA_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PPHEPGDA_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PPHEPGDA_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PPHEPGDA_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPHEPGDA_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PPHEPGDA_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PPHEPGDA_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PPHEPGDA_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PPHEPGDA_00153 1.9e-23 rpmD J Ribosomal protein L30
PPHEPGDA_00154 1.8e-72 rplO J binds to the 23S rRNA
PPHEPGDA_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PPHEPGDA_00156 1.3e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PPHEPGDA_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
PPHEPGDA_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PPHEPGDA_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PPHEPGDA_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PPHEPGDA_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PPHEPGDA_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PPHEPGDA_00163 3.6e-58 rplQ J Ribosomal protein L17
PPHEPGDA_00164 5.6e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPHEPGDA_00165 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPHEPGDA_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PPHEPGDA_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PPHEPGDA_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PPHEPGDA_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PPHEPGDA_00170 1.5e-143 ybaJ Q Methyltransferase domain
PPHEPGDA_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
PPHEPGDA_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PPHEPGDA_00174 1.2e-84 gerD
PPHEPGDA_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
PPHEPGDA_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
PPHEPGDA_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00180 2e-08
PPHEPGDA_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00186 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
PPHEPGDA_00187 6e-44 tnpIS3 L Transposase
PPHEPGDA_00188 1.5e-134 L Integrase core domain
PPHEPGDA_00189 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
PPHEPGDA_00190 7e-141 ybbA S Putative esterase
PPHEPGDA_00191 1.5e-178 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00192 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00193 4e-165 feuA P Iron-uptake system-binding protein
PPHEPGDA_00194 2.3e-303 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
PPHEPGDA_00195 7.8e-238 ybbC 3.2.1.52 S protein conserved in bacteria
PPHEPGDA_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
PPHEPGDA_00197 1.8e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
PPHEPGDA_00198 1.3e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_00199 7.4e-147 ybbH K transcriptional
PPHEPGDA_00200 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PPHEPGDA_00201 7.1e-86 ybbJ J acetyltransferase
PPHEPGDA_00202 4.3e-77 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
PPHEPGDA_00208 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_00209 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
PPHEPGDA_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PPHEPGDA_00211 1.5e-224 ybbR S protein conserved in bacteria
PPHEPGDA_00212 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PPHEPGDA_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PPHEPGDA_00216 0.0 papA4 Q amino acid activation for nonribosomal peptide biosynthetic process
PPHEPGDA_00217 0.0 1.3.3.6, 1.8.1.9, 1.8.7.3, 1.8.98.4, 1.8.98.5, 1.8.98.6 IQ PKS_KR
PPHEPGDA_00218 1.9e-44 mepB S MepB protein
PPHEPGDA_00219 8.9e-47 pksB 3.1.2.6 S Metallo-beta-lactamase superfamily
PPHEPGDA_00220 5.9e-272 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PPHEPGDA_00221 0.0 ybcC S Belongs to the UPF0753 family
PPHEPGDA_00222 6.5e-93 can 4.2.1.1 P carbonic anhydrase
PPHEPGDA_00223 3.9e-47
PPHEPGDA_00224 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
PPHEPGDA_00225 1.5e-50 T Transcriptional regulatory protein, C terminal
PPHEPGDA_00226 1.1e-55 T His Kinase A (phospho-acceptor) domain
PPHEPGDA_00227 3.3e-103 T His Kinase A (phospho-acceptor) domain
PPHEPGDA_00229 5.7e-138 KLT Protein tyrosine kinase
PPHEPGDA_00230 2.9e-151 ybdN
PPHEPGDA_00231 1.8e-212 ybdO S Domain of unknown function (DUF4885)
PPHEPGDA_00232 1.3e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_00233 3.8e-27 csgA S Sigma-G-dependent sporulation-specific SASP protein
PPHEPGDA_00234 4.9e-30 ybxH S Family of unknown function (DUF5370)
PPHEPGDA_00235 3.4e-149 ybxI 3.5.2.6 V beta-lactamase
PPHEPGDA_00236 3.6e-243 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
PPHEPGDA_00237 4.9e-41 ybyB
PPHEPGDA_00238 1.8e-290 ybeC E amino acid
PPHEPGDA_00239 1.3e-165 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PPHEPGDA_00240 7.3e-258 glpT G -transporter
PPHEPGDA_00241 8.5e-35 S Protein of unknown function (DUF2651)
PPHEPGDA_00242 3.3e-153 ybfA 3.4.15.5 K FR47-like protein
PPHEPGDA_00243 1.7e-143 ybfB G COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_00244 2.7e-46 ybfB G COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_00247 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
PPHEPGDA_00248 2.4e-159 ybfH EG EamA-like transporter family
PPHEPGDA_00249 6.7e-145 msmR K AraC-like ligand binding domain
PPHEPGDA_00250 2.8e-33 K sigma factor activity
PPHEPGDA_00251 9e-21 xhlB S SPP1 phage holin
PPHEPGDA_00252 2e-164 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
PPHEPGDA_00253 3.9e-57
PPHEPGDA_00255 2.6e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PPHEPGDA_00256 5.8e-177 mpr 3.4.21.19 M Belongs to the peptidase S1B family
PPHEPGDA_00258 4.7e-168 S Alpha/beta hydrolase family
PPHEPGDA_00259 9.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPHEPGDA_00260 2.7e-85 ybfM S SNARE associated Golgi protein
PPHEPGDA_00261 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
PPHEPGDA_00262 4.6e-45 ybfN
PPHEPGDA_00263 3.4e-255 S Erythromycin esterase
PPHEPGDA_00264 6.7e-167 ybfP K Transcriptional regulator
PPHEPGDA_00265 3.9e-192 yceA S Belongs to the UPF0176 family
PPHEPGDA_00266 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PPHEPGDA_00267 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_00268 1.1e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PPHEPGDA_00269 4.9e-128 K UTRA
PPHEPGDA_00271 1.3e-201 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PPHEPGDA_00272 3.7e-260 mmuP E amino acid
PPHEPGDA_00273 4.6e-182 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
PPHEPGDA_00274 9.6e-256 agcS E Sodium alanine symporter
PPHEPGDA_00275 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
PPHEPGDA_00276 9.4e-229 phoQ 2.7.13.3 T Histidine kinase
PPHEPGDA_00277 2.2e-168 glnL T Regulator
PPHEPGDA_00278 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
PPHEPGDA_00279 1.9e-270 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_00280 5.9e-255 gudP G COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_00281 7.2e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PPHEPGDA_00282 5.6e-124 ycbG K FCD
PPHEPGDA_00283 2.3e-182 garD 4.2.1.42, 4.2.1.7 G Altronate
PPHEPGDA_00284 1.1e-95 ycbJ S Macrolide 2'-phosphotransferase
PPHEPGDA_00285 1.7e-51 ycbJ S Macrolide 2'-phosphotransferase
PPHEPGDA_00286 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
PPHEPGDA_00287 6.4e-168 eamA1 EG spore germination
PPHEPGDA_00288 3.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_00289 5.4e-167 T PhoQ Sensor
PPHEPGDA_00290 1.8e-167 ycbN V ABC transporter, ATP-binding protein
PPHEPGDA_00291 1.8e-114 S ABC-2 family transporter protein
PPHEPGDA_00292 8.2e-53 ycbP S Protein of unknown function (DUF2512)
PPHEPGDA_00293 2.8e-78 sleB 3.5.1.28 M Cell wall
PPHEPGDA_00294 4e-133 ycbR T vWA found in TerF C terminus
PPHEPGDA_00295 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
PPHEPGDA_00296 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PPHEPGDA_00297 1.7e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PPHEPGDA_00298 7.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PPHEPGDA_00299 2.8e-202 ycbU E Selenocysteine lyase
PPHEPGDA_00300 5.8e-229 lmrB EGP the major facilitator superfamily
PPHEPGDA_00301 1.6e-100 yxaF K Transcriptional regulator
PPHEPGDA_00302 1.5e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PPHEPGDA_00303 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
PPHEPGDA_00304 2e-59 S RDD family
PPHEPGDA_00305 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
PPHEPGDA_00306 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00307 1.4e-45 L transposase activity
PPHEPGDA_00308 5.3e-126 2.7.13.3 T GHKL domain
PPHEPGDA_00309 2.3e-125 lytR_2 T LytTr DNA-binding domain
PPHEPGDA_00310 1.2e-132 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
PPHEPGDA_00311 4.2e-201 natB CP ABC-2 family transporter protein
PPHEPGDA_00312 4.6e-174 yccK C Aldo keto reductase
PPHEPGDA_00313 2.2e-180 ycdA S Domain of unknown function (DUF5105)
PPHEPGDA_00314 9.4e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_00315 2.2e-258 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_00316 2.1e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
PPHEPGDA_00317 7.9e-173 S response regulator aspartate phosphatase
PPHEPGDA_00318 5.7e-138 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_00319 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
PPHEPGDA_00320 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
PPHEPGDA_00321 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PPHEPGDA_00322 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PPHEPGDA_00323 1.2e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPHEPGDA_00324 1.3e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
PPHEPGDA_00325 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
PPHEPGDA_00326 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
PPHEPGDA_00327 1.4e-136 terC P Protein of unknown function (DUF475)
PPHEPGDA_00328 0.0 yceG S Putative component of 'biosynthetic module'
PPHEPGDA_00329 2e-192 yceH P Belongs to the TelA family
PPHEPGDA_00330 9.6e-217 naiP P Uncharacterised MFS-type transporter YbfB
PPHEPGDA_00331 2.6e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
PPHEPGDA_00332 3.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
PPHEPGDA_00333 2.5e-228 proV 3.6.3.32 E glycine betaine
PPHEPGDA_00334 1.3e-127 opuAB P glycine betaine
PPHEPGDA_00335 1.3e-162 opuAC E glycine betaine
PPHEPGDA_00336 7e-217 amhX S amidohydrolase
PPHEPGDA_00337 8.7e-257 ycgA S Membrane
PPHEPGDA_00338 2.3e-44 ycgB
PPHEPGDA_00339 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
PPHEPGDA_00340 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PPHEPGDA_00341 1.5e-66 lctP C L-lactate permease
PPHEPGDA_00342 1e-210 lctP C L-lactate permease
PPHEPGDA_00343 1.4e-149 yqcI S YqcI/YcgG family
PPHEPGDA_00344 2.4e-76 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_00345 2.4e-112 ycgI S Domain of unknown function (DUF1989)
PPHEPGDA_00346 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PPHEPGDA_00347 9.5e-109 tmrB S AAA domain
PPHEPGDA_00348 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PPHEPGDA_00349 6.4e-142 yafE Q ubiE/COQ5 methyltransferase family
PPHEPGDA_00350 3.2e-178 oxyR3 K LysR substrate binding domain
PPHEPGDA_00351 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
PPHEPGDA_00352 2.9e-145 ycgL S Predicted nucleotidyltransferase
PPHEPGDA_00353 5.1e-170 ycgM E Proline dehydrogenase
PPHEPGDA_00354 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PPHEPGDA_00355 2e-247 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PPHEPGDA_00356 4.7e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
PPHEPGDA_00357 5.7e-147 ycgQ S membrane
PPHEPGDA_00358 7.7e-139 ycgR S permeases
PPHEPGDA_00359 4.3e-155 I alpha/beta hydrolase fold
PPHEPGDA_00360 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PPHEPGDA_00361 9.9e-277 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PPHEPGDA_00362 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
PPHEPGDA_00363 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PPHEPGDA_00364 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PPHEPGDA_00365 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
PPHEPGDA_00366 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
PPHEPGDA_00367 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
PPHEPGDA_00368 5.5e-109 yciB M ErfK YbiS YcfS YnhG
PPHEPGDA_00369 1.6e-227 yciC S GTPases (G3E family)
PPHEPGDA_00370 1.6e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
PPHEPGDA_00371 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
PPHEPGDA_00373 7.8e-52 yckD S Protein of unknown function (DUF2680)
PPHEPGDA_00374 1.6e-38 K MarR family
PPHEPGDA_00375 9.3e-24
PPHEPGDA_00376 7.8e-121 S AAA domain
PPHEPGDA_00377 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPHEPGDA_00378 1.7e-69 nin S Competence protein J (ComJ)
PPHEPGDA_00379 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
PPHEPGDA_00380 9.3e-57 tlpC 2.7.13.3 NT chemotaxis protein
PPHEPGDA_00381 7.8e-115 tlpC 2.7.13.3 NT chemotaxis protein
PPHEPGDA_00382 3e-96 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
PPHEPGDA_00383 8e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
PPHEPGDA_00384 1.3e-63 hxlR K transcriptional
PPHEPGDA_00385 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_00386 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_00387 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
PPHEPGDA_00388 2.2e-139 srfAD Q thioesterase
PPHEPGDA_00389 8.8e-226 EGP Major Facilitator Superfamily
PPHEPGDA_00390 3.5e-89 S YcxB-like protein
PPHEPGDA_00391 1.1e-156 ycxC EG EamA-like transporter family
PPHEPGDA_00392 2.1e-29 ycxD K GntR family transcriptional regulator
PPHEPGDA_00393 2.5e-116 ycxD K GntR family transcriptional regulator
PPHEPGDA_00394 5.5e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
PPHEPGDA_00395 9.7e-115 yczE S membrane
PPHEPGDA_00396 8.2e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PPHEPGDA_00397 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
PPHEPGDA_00398 4.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PPHEPGDA_00399 1.9e-161 bsdA K LysR substrate binding domain
PPHEPGDA_00400 3.4e-08 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PPHEPGDA_00401 6e-157 yclE 3.4.11.5 S Alpha beta hydrolase
PPHEPGDA_00402 7.8e-261 dtpT E amino acid peptide transporter
PPHEPGDA_00403 5.9e-292 yclG M Pectate lyase superfamily protein
PPHEPGDA_00405 9.5e-276 gerKA EG Spore germination protein
PPHEPGDA_00406 8e-227 gerKC S spore germination
PPHEPGDA_00407 7.6e-192 gerKB F Spore germination protein
PPHEPGDA_00408 3.6e-120 yclH P ABC transporter
PPHEPGDA_00409 4e-201 yclI V ABC transporter (permease) YclI
PPHEPGDA_00410 2.1e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_00411 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PPHEPGDA_00412 1.2e-70 S aspartate phosphatase
PPHEPGDA_00415 1.7e-238 lysC 2.7.2.4 E Belongs to the aspartokinase family
PPHEPGDA_00417 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00418 6.3e-163 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00419 1.1e-136 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
PPHEPGDA_00420 1.6e-169 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
PPHEPGDA_00421 4.9e-75 V Restriction endonuclease
PPHEPGDA_00422 3.2e-251 ycnB EGP Major facilitator Superfamily
PPHEPGDA_00423 6.5e-154 ycnC K Transcriptional regulator
PPHEPGDA_00424 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
PPHEPGDA_00425 4.7e-45 ycnE S Monooxygenase
PPHEPGDA_00426 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
PPHEPGDA_00427 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_00428 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PPHEPGDA_00429 5.4e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_00430 6.1e-149 glcU U Glucose uptake
PPHEPGDA_00431 9.2e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_00432 6.6e-97 ycnI S protein conserved in bacteria
PPHEPGDA_00433 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
PPHEPGDA_00434 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
PPHEPGDA_00435 7.3e-56
PPHEPGDA_00436 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
PPHEPGDA_00437 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
PPHEPGDA_00438 5.8e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
PPHEPGDA_00439 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
PPHEPGDA_00440 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PPHEPGDA_00441 3.2e-74 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PPHEPGDA_00442 1.5e-18 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
PPHEPGDA_00443 4.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PPHEPGDA_00445 6.8e-136 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PPHEPGDA_00446 1.8e-139 ycsF S Belongs to the UPF0271 (lamB) family
PPHEPGDA_00447 1.6e-211 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
PPHEPGDA_00448 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
PPHEPGDA_00449 1.8e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
PPHEPGDA_00450 5.6e-186 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
PPHEPGDA_00451 2.7e-132 kipR K Transcriptional regulator
PPHEPGDA_00452 2.9e-119 ycsK E anatomical structure formation involved in morphogenesis
PPHEPGDA_00454 5.4e-49 yczJ S biosynthesis
PPHEPGDA_00455 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
PPHEPGDA_00456 2.4e-172 ydhF S Oxidoreductase
PPHEPGDA_00457 0.0 mtlR K transcriptional regulator, MtlR
PPHEPGDA_00458 2.1e-293 ydaB IQ acyl-CoA ligase
PPHEPGDA_00459 9e-99 ydaC Q Methyltransferase domain
PPHEPGDA_00460 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_00461 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
PPHEPGDA_00462 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PPHEPGDA_00463 6.8e-77 ydaG 1.4.3.5 S general stress protein
PPHEPGDA_00464 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
PPHEPGDA_00465 3.6e-45 ydzA EGP Major facilitator Superfamily
PPHEPGDA_00466 2.5e-74 lrpC K Transcriptional regulator
PPHEPGDA_00467 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PPHEPGDA_00468 5.2e-75 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PPHEPGDA_00469 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PPHEPGDA_00471 1.8e-27
PPHEPGDA_00472 1.8e-72 sdpB S Protein conserved in bacteria
PPHEPGDA_00474 9.4e-40
PPHEPGDA_00475 3e-224 mntH P H( )-stimulated, divalent metal cation uptake system
PPHEPGDA_00477 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
PPHEPGDA_00478 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
PPHEPGDA_00480 8.9e-59 ydbB G Cupin domain
PPHEPGDA_00481 2.6e-61 ydbC S Domain of unknown function (DUF4937
PPHEPGDA_00482 1.3e-57 ydbD P Catalase
PPHEPGDA_00483 2.8e-82 ydbD P Catalase
PPHEPGDA_00484 6e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
PPHEPGDA_00485 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PPHEPGDA_00486 6.8e-119 dctR T COG4565 Response regulator of citrate malate metabolism
PPHEPGDA_00487 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PPHEPGDA_00488 8.2e-180 ydbI S AI-2E family transporter
PPHEPGDA_00490 1.4e-170 ydbJ V ABC transporter, ATP-binding protein
PPHEPGDA_00491 2.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PPHEPGDA_00492 2.7e-52 ydbL
PPHEPGDA_00493 1.5e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
PPHEPGDA_00494 1.1e-18 S Fur-regulated basic protein B
PPHEPGDA_00495 2.2e-07 S Fur-regulated basic protein A
PPHEPGDA_00496 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPHEPGDA_00497 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PPHEPGDA_00498 1.8e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PPHEPGDA_00499 6.7e-257 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PPHEPGDA_00500 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PPHEPGDA_00501 2.1e-82 ydbS S Bacterial PH domain
PPHEPGDA_00502 8.4e-263 ydbT S Membrane
PPHEPGDA_00503 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
PPHEPGDA_00504 1.4e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PPHEPGDA_00505 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
PPHEPGDA_00506 2.5e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PPHEPGDA_00507 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
PPHEPGDA_00508 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
PPHEPGDA_00509 3.7e-143 rsbR T Positive regulator of sigma-B
PPHEPGDA_00510 5.2e-57 rsbS T antagonist
PPHEPGDA_00511 3.8e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
PPHEPGDA_00512 3.5e-188 rsbU 3.1.3.3 KT phosphatase
PPHEPGDA_00513 1.6e-52 rsbV T Belongs to the anti-sigma-factor antagonist family
PPHEPGDA_00514 6e-85 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
PPHEPGDA_00515 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_00516 1.4e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
PPHEPGDA_00517 0.0 yhgF K COG2183 Transcriptional accessory protein
PPHEPGDA_00518 8.9e-83 ydcK S Belongs to the SprT family
PPHEPGDA_00526 7.7e-116 yecA E amino acid
PPHEPGDA_00527 4.6e-107 K Transcriptional regulator
PPHEPGDA_00528 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
PPHEPGDA_00529 8.5e-45
PPHEPGDA_00530 3e-139 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PPHEPGDA_00531 5.6e-34 K Helix-turn-helix XRE-family like proteins
PPHEPGDA_00532 1.9e-40
PPHEPGDA_00536 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
PPHEPGDA_00537 8.7e-30 cspL K Cold shock
PPHEPGDA_00538 2.3e-78 carD K Transcription factor
PPHEPGDA_00539 1.6e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PPHEPGDA_00540 5.8e-163 rhaS5 K AraC-like ligand binding domain
PPHEPGDA_00541 2.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PPHEPGDA_00542 6.9e-164 ydeE K AraC family transcriptional regulator
PPHEPGDA_00543 2.8e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_00544 3.3e-215 ydeG EGP Major facilitator superfamily
PPHEPGDA_00545 2.7e-45 ydeH
PPHEPGDA_00546 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
PPHEPGDA_00547 1.3e-109
PPHEPGDA_00548 1.4e-27 S SNARE associated Golgi protein
PPHEPGDA_00549 1.8e-14 ptsH G PTS HPr component phosphorylation site
PPHEPGDA_00550 3.4e-84 K Transcriptional regulator C-terminal region
PPHEPGDA_00551 2e-152 ydeK EG -transporter
PPHEPGDA_00552 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_00553 1.3e-72 maoC I N-terminal half of MaoC dehydratase
PPHEPGDA_00554 1.8e-104 ydeN S Serine hydrolase
PPHEPGDA_00555 5.7e-55 K HxlR-like helix-turn-helix
PPHEPGDA_00556 6e-152 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PPHEPGDA_00557 8.2e-57 arsR K transcriptional
PPHEPGDA_00558 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PPHEPGDA_00559 3.7e-145 ydfB J GNAT acetyltransferase
PPHEPGDA_00560 5.2e-154 ydfC EG EamA-like transporter family
PPHEPGDA_00561 3.9e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_00562 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
PPHEPGDA_00563 1.4e-115 ydfE S Flavin reductase like domain
PPHEPGDA_00564 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
PPHEPGDA_00565 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PPHEPGDA_00567 1.7e-178 ydfH 2.7.13.3 T Histidine kinase
PPHEPGDA_00568 4.2e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_00569 0.0 ydfJ S drug exporters of the RND superfamily
PPHEPGDA_00571 1.3e-173 S Alpha/beta hydrolase family
PPHEPGDA_00572 7.2e-116 S Protein of unknown function (DUF554)
PPHEPGDA_00573 9.2e-147 K Bacterial transcription activator, effector binding domain
PPHEPGDA_00574 1.7e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPHEPGDA_00575 2.6e-109 ydfN C nitroreductase
PPHEPGDA_00576 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
PPHEPGDA_00577 8.8e-63 mhqP S DoxX
PPHEPGDA_00578 4.2e-53 traF CO Thioredoxin
PPHEPGDA_00579 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
PPHEPGDA_00580 4.8e-29
PPHEPGDA_00582 4.4e-118 ydfR S Protein of unknown function (DUF421)
PPHEPGDA_00583 1.5e-121 ydfS S Protein of unknown function (DUF421)
PPHEPGDA_00584 1.9e-74 cotP O Belongs to the small heat shock protein (HSP20) family
PPHEPGDA_00585 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
PPHEPGDA_00586 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
PPHEPGDA_00587 1e-97 K Bacterial regulatory proteins, tetR family
PPHEPGDA_00588 1.6e-52 S DoxX-like family
PPHEPGDA_00589 8.5e-84 yycN 2.3.1.128 K Acetyltransferase
PPHEPGDA_00590 3.2e-303 expZ S ABC transporter
PPHEPGDA_00591 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_00592 4.7e-88 dinB S DinB family
PPHEPGDA_00593 2e-78 K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_00594 0.0 ydgH S drug exporters of the RND superfamily
PPHEPGDA_00595 1e-113 drgA C nitroreductase
PPHEPGDA_00596 2.4e-69 ydgJ K Winged helix DNA-binding domain
PPHEPGDA_00597 6.3e-208 tcaB EGP Major facilitator Superfamily
PPHEPGDA_00598 4.6e-121 ydhB S membrane transporter protein
PPHEPGDA_00599 6.5e-122 ydhC K FCD
PPHEPGDA_00600 1.6e-243 ydhD M Glycosyl hydrolase
PPHEPGDA_00601 1.7e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PPHEPGDA_00602 1.3e-125
PPHEPGDA_00603 9.9e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
PPHEPGDA_00604 4.3e-67 frataxin S Domain of unknown function (DU1801)
PPHEPGDA_00606 2.9e-84 K Acetyltransferase (GNAT) domain
PPHEPGDA_00607 8.4e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PPHEPGDA_00608 1.7e-99 ydhK M Protein of unknown function (DUF1541)
PPHEPGDA_00609 4.6e-200 pbuE EGP Major facilitator Superfamily
PPHEPGDA_00610 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
PPHEPGDA_00611 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
PPHEPGDA_00612 6.4e-137 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPHEPGDA_00613 2.2e-91 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPHEPGDA_00614 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPHEPGDA_00615 3.3e-132 ydhQ K UTRA
PPHEPGDA_00616 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
PPHEPGDA_00617 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
PPHEPGDA_00618 1.2e-213 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
PPHEPGDA_00619 1.8e-133 ydhU P Catalase
PPHEPGDA_00622 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00623 7.8e-08
PPHEPGDA_00625 7.1e-178 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PPHEPGDA_00626 3.5e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
PPHEPGDA_00627 3.8e-125 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
PPHEPGDA_00628 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PPHEPGDA_00629 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PPHEPGDA_00630 0.0 ydiF S ABC transporter
PPHEPGDA_00631 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
PPHEPGDA_00632 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PPHEPGDA_00633 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
PPHEPGDA_00634 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PPHEPGDA_00635 2.9e-27 ydiK S Domain of unknown function (DUF4305)
PPHEPGDA_00636 7.9e-129 ydiL S CAAX protease self-immunity
PPHEPGDA_00637 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PPHEPGDA_00638 1.1e-279 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PPHEPGDA_00640 6e-114 cll
PPHEPGDA_00641 5e-136
PPHEPGDA_00642 0.0 K NB-ARC domain
PPHEPGDA_00643 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
PPHEPGDA_00644 3.1e-251 gutA G MFS/sugar transport protein
PPHEPGDA_00645 1.2e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
PPHEPGDA_00646 9.6e-113 pspA KT Phage shock protein A
PPHEPGDA_00647 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PPHEPGDA_00648 1.8e-131 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
PPHEPGDA_00649 2.6e-148 ydjI S virion core protein (lumpy skin disease virus)
PPHEPGDA_00650 2.8e-193 S Ion transport 2 domain protein
PPHEPGDA_00651 7.8e-258 iolT EGP Major facilitator Superfamily
PPHEPGDA_00652 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PPHEPGDA_00653 4.5e-64 ydjM M Lytic transglycolase
PPHEPGDA_00654 6.1e-151 ydjN U Involved in the tonB-independent uptake of proteins
PPHEPGDA_00655 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00656 1.4e-45 L transposase activity
PPHEPGDA_00658 1.2e-34 ydjO S Cold-inducible protein YdjO
PPHEPGDA_00659 2e-157 ydjP I Alpha/beta hydrolase family
PPHEPGDA_00660 5.5e-178 yeaA S Protein of unknown function (DUF4003)
PPHEPGDA_00661 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
PPHEPGDA_00662 3.3e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_00663 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PPHEPGDA_00664 5e-176 yeaC S COG0714 MoxR-like ATPases
PPHEPGDA_00665 7.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
PPHEPGDA_00666 0.0 yebA E COG1305 Transglutaminase-like enzymes
PPHEPGDA_00667 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PPHEPGDA_00668 8.6e-85 K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_00669 1.2e-248 S Domain of unknown function (DUF4179)
PPHEPGDA_00670 1.5e-210 pbuG S permease
PPHEPGDA_00671 2.4e-115 yebC M Membrane
PPHEPGDA_00673 4e-93 yebE S UPF0316 protein
PPHEPGDA_00674 8e-28 yebG S NETI protein
PPHEPGDA_00675 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PPHEPGDA_00676 4.5e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PPHEPGDA_00677 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PPHEPGDA_00678 4.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PPHEPGDA_00679 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PPHEPGDA_00680 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PPHEPGDA_00681 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PPHEPGDA_00682 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PPHEPGDA_00683 1.1e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PPHEPGDA_00684 8.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PPHEPGDA_00685 4.3e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PPHEPGDA_00686 5.9e-233 purD 6.3.4.13 F Belongs to the GARS family
PPHEPGDA_00687 2.8e-70 K helix_turn_helix ASNC type
PPHEPGDA_00688 6.8e-229 yjeH E Amino acid permease
PPHEPGDA_00689 2.7e-27 S Protein of unknown function (DUF2892)
PPHEPGDA_00690 0.0 yerA 3.5.4.2 F adenine deaminase
PPHEPGDA_00691 4.9e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
PPHEPGDA_00692 2.4e-50 yerC S protein conserved in bacteria
PPHEPGDA_00693 5.2e-303 yerD 1.4.7.1 E Belongs to the glutamate synthase family
PPHEPGDA_00695 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PPHEPGDA_00696 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PPHEPGDA_00697 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PPHEPGDA_00698 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
PPHEPGDA_00699 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00700 1.4e-45 L transposase activity
PPHEPGDA_00701 7.8e-196 yerI S homoserine kinase type II (protein kinase fold)
PPHEPGDA_00702 1.6e-123 sapB S MgtC SapB transporter
PPHEPGDA_00703 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PPHEPGDA_00704 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPHEPGDA_00705 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PPHEPGDA_00706 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PPHEPGDA_00707 2.8e-146 yerO K Transcriptional regulator
PPHEPGDA_00708 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PPHEPGDA_00709 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PPHEPGDA_00710 7.1e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPHEPGDA_00711 8.4e-240 2.1.1.37 H PFAM C-5 cytosine-specific DNA methylase
PPHEPGDA_00712 7.6e-222 L Restriction endonuclease MspI
PPHEPGDA_00713 8.2e-28 K Psort location Cytoplasmic, score
PPHEPGDA_00714 0.0 E Zn peptidase
PPHEPGDA_00715 1.9e-71
PPHEPGDA_00716 5.2e-270
PPHEPGDA_00717 5.4e-150
PPHEPGDA_00719 1.1e-07 S Tetratricopeptide repeat
PPHEPGDA_00720 5.5e-69 S response regulator aspartate phosphatase
PPHEPGDA_00723 2.7e-82 S Protein of unknown function, DUF600
PPHEPGDA_00724 0.0 L nucleic acid phosphodiester bond hydrolysis
PPHEPGDA_00726 1.3e-99 L endonuclease activity
PPHEPGDA_00727 5.7e-49
PPHEPGDA_00728 3.1e-209 S Tetratricopeptide repeat
PPHEPGDA_00730 2.7e-126 yeeN K transcriptional regulatory protein
PPHEPGDA_00732 6.7e-99 dhaR3 K Transcriptional regulator
PPHEPGDA_00733 6.9e-80 yesE S SnoaL-like domain
PPHEPGDA_00734 1.3e-151 yesF GM NAD(P)H-binding
PPHEPGDA_00735 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
PPHEPGDA_00736 1.5e-45 cotJB S CotJB protein
PPHEPGDA_00737 2e-103 cotJC P Spore Coat
PPHEPGDA_00738 6e-102 yesJ K Acetyltransferase (GNAT) family
PPHEPGDA_00740 5e-100 yesL S Protein of unknown function, DUF624
PPHEPGDA_00741 0.0 yesM 2.7.13.3 T Histidine kinase
PPHEPGDA_00742 1.6e-158 yesN K helix_turn_helix, arabinose operon control protein
PPHEPGDA_00743 5.2e-245 yesO G Bacterial extracellular solute-binding protein
PPHEPGDA_00744 1e-170 yesP G Binding-protein-dependent transport system inner membrane component
PPHEPGDA_00745 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
PPHEPGDA_00746 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
PPHEPGDA_00747 0.0 yesS K Transcriptional regulator
PPHEPGDA_00748 2.7e-131 E GDSL-like Lipase/Acylhydrolase
PPHEPGDA_00749 6e-128 yesU S Domain of unknown function (DUF1961)
PPHEPGDA_00750 5.3e-110 yesV S Protein of unknown function, DUF624
PPHEPGDA_00751 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
PPHEPGDA_00752 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
PPHEPGDA_00753 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
PPHEPGDA_00754 4e-64 yesZ 3.2.1.23 G beta-galactosidase activity
PPHEPGDA_00755 1.6e-123 yesZ 3.2.1.23 G beta-galactosidase activity
PPHEPGDA_00756 7.1e-155 yesZ 3.2.1.23 G beta-galactosidase activity
PPHEPGDA_00757 0.0 yetA
PPHEPGDA_00758 6.2e-290 lplA G Bacterial extracellular solute-binding protein
PPHEPGDA_00759 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
PPHEPGDA_00760 1.4e-161 lplC G Binding-protein-dependent transport system inner membrane component
PPHEPGDA_00761 1.7e-254 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
PPHEPGDA_00762 4e-122 yetF S membrane
PPHEPGDA_00763 3.7e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
PPHEPGDA_00764 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_00765 2.5e-34
PPHEPGDA_00766 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PPHEPGDA_00767 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
PPHEPGDA_00768 2.6e-104 yetJ S Belongs to the BI1 family
PPHEPGDA_00769 1.2e-158 yetK EG EamA-like transporter family
PPHEPGDA_00770 5.9e-22 yetL K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_00771 1.6e-17 yetL K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_00772 3.9e-43 tnpIS3 L Transposase
PPHEPGDA_00773 1.5e-134 L Integrase core domain
PPHEPGDA_00774 3.6e-199 yetN S Protein of unknown function (DUF3900)
PPHEPGDA_00775 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PPHEPGDA_00776 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPHEPGDA_00777 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
PPHEPGDA_00778 1.9e-186 yfnG 4.2.1.45 M dehydratase
PPHEPGDA_00779 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
PPHEPGDA_00780 5.1e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
PPHEPGDA_00781 2.5e-188 yfnD M Nucleotide-diphospho-sugar transferase
PPHEPGDA_00782 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_00783 2.4e-130 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PPHEPGDA_00784 1.2e-189 yfnA E amino acid
PPHEPGDA_00785 2.2e-34 yfnA E amino acid
PPHEPGDA_00786 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_00787 1.1e-113 yfmS NT chemotaxis protein
PPHEPGDA_00788 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PPHEPGDA_00789 2.6e-74 yfmQ S Uncharacterised protein from bacillus cereus group
PPHEPGDA_00790 1.4e-69 yfmP K transcriptional
PPHEPGDA_00791 4.3e-209 yfmO EGP Major facilitator Superfamily
PPHEPGDA_00792 4.7e-35
PPHEPGDA_00793 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PPHEPGDA_00794 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
PPHEPGDA_00795 5.2e-75 yfmK 2.3.1.128 K acetyltransferase
PPHEPGDA_00796 2.1e-188 yfmJ S N-terminal domain of oxidoreductase
PPHEPGDA_00797 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
PPHEPGDA_00798 4e-168 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00799 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00800 3.6e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
PPHEPGDA_00801 2.9e-24 S Protein of unknown function (DUF3212)
PPHEPGDA_00802 7.6e-58 yflT S Heat induced stress protein YflT
PPHEPGDA_00803 1.9e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
PPHEPGDA_00804 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
PPHEPGDA_00805 1.8e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PPHEPGDA_00806 2.2e-117 citT T response regulator
PPHEPGDA_00807 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
PPHEPGDA_00808 8.5e-227 citM C Citrate transporter
PPHEPGDA_00809 6.7e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
PPHEPGDA_00810 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
PPHEPGDA_00811 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PPHEPGDA_00812 6.4e-122 yflK S protein conserved in bacteria
PPHEPGDA_00813 8.9e-18 yflJ S Protein of unknown function (DUF2639)
PPHEPGDA_00814 4.1e-19 yflI
PPHEPGDA_00815 5.9e-49 yflH S Protein of unknown function (DUF3243)
PPHEPGDA_00816 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
PPHEPGDA_00817 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
PPHEPGDA_00818 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPHEPGDA_00819 6e-67 yhdN S Domain of unknown function (DUF1992)
PPHEPGDA_00820 4.1e-251 agcS_1 E Sodium alanine symporter
PPHEPGDA_00821 9e-27 yfkQ EG Spore germination protein
PPHEPGDA_00822 1.2e-51 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_00823 1.3e-185 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_00824 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PPHEPGDA_00825 1.8e-133 treR K transcriptional
PPHEPGDA_00826 1.1e-124 yfkO C nitroreductase
PPHEPGDA_00827 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PPHEPGDA_00828 1.2e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
PPHEPGDA_00829 5.8e-206 ydiM EGP Major facilitator Superfamily
PPHEPGDA_00830 1.3e-28 yfkK S Belongs to the UPF0435 family
PPHEPGDA_00831 1.9e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PPHEPGDA_00832 2.4e-50 yfkI S gas vesicle protein
PPHEPGDA_00833 1.3e-143 yihY S Belongs to the UPF0761 family
PPHEPGDA_00834 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_00835 1.8e-182 cax P COG0387 Ca2 H antiporter
PPHEPGDA_00836 1.2e-146 yfkD S YfkD-like protein
PPHEPGDA_00837 3.9e-148 yfkC M Mechanosensitive ion channel
PPHEPGDA_00838 5.4e-222 yfkA S YfkB-like domain
PPHEPGDA_00839 1.1e-26 yfjT
PPHEPGDA_00840 1.7e-153 pdaA G deacetylase
PPHEPGDA_00841 3.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
PPHEPGDA_00842 1e-181 corA P Mediates influx of magnesium ions
PPHEPGDA_00843 1.7e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
PPHEPGDA_00844 2.4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PPHEPGDA_00845 3.9e-44 S YfzA-like protein
PPHEPGDA_00846 2.4e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PPHEPGDA_00847 1.9e-85 yfjM S Psort location Cytoplasmic, score
PPHEPGDA_00848 2.3e-29 yfjL
PPHEPGDA_00849 4.9e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PPHEPGDA_00850 3.8e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PPHEPGDA_00851 9.3e-196 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PPHEPGDA_00852 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PPHEPGDA_00853 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
PPHEPGDA_00854 1.7e-24 sspH S Belongs to the SspH family
PPHEPGDA_00855 1.1e-55 yfjF S UPF0060 membrane protein
PPHEPGDA_00856 4.1e-82 S Family of unknown function (DUF5381)
PPHEPGDA_00857 6.9e-101 yfjD S Family of unknown function (DUF5381)
PPHEPGDA_00858 9e-144 yfjC
PPHEPGDA_00859 2.7e-190 yfjB
PPHEPGDA_00860 1.1e-44 yfjA S Belongs to the WXG100 family
PPHEPGDA_00861 2.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PPHEPGDA_00862 8.1e-137 glvR K Helix-turn-helix domain, rpiR family
PPHEPGDA_00863 8.8e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_00864 0.0 yobO M COG5434 Endopolygalacturonase
PPHEPGDA_00865 2.4e-306 yfiB3 V ABC transporter
PPHEPGDA_00866 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
PPHEPGDA_00867 9.8e-65 mhqP S DoxX
PPHEPGDA_00868 5.7e-163 yfiE 1.13.11.2 S glyoxalase
PPHEPGDA_00869 1.5e-177 K AraC-like ligand binding domain
PPHEPGDA_00870 1.8e-262 iolT EGP Major facilitator Superfamily
PPHEPGDA_00871 8.4e-184 G Xylose isomerase
PPHEPGDA_00872 5.1e-26 S Oxidoreductase
PPHEPGDA_00873 2.2e-198 S Oxidoreductase
PPHEPGDA_00875 3.6e-213 yxjM T Histidine kinase
PPHEPGDA_00876 5.4e-113 KT LuxR family transcriptional regulator
PPHEPGDA_00877 1.9e-167 V ABC transporter, ATP-binding protein
PPHEPGDA_00878 2.9e-205 V ABC-2 family transporter protein
PPHEPGDA_00879 4e-204 V COG0842 ABC-type multidrug transport system, permease component
PPHEPGDA_00880 8.3e-99 padR K transcriptional
PPHEPGDA_00881 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
PPHEPGDA_00882 7.6e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
PPHEPGDA_00883 1.4e-107 yfiR K Transcriptional regulator
PPHEPGDA_00884 1e-200 yfiS EGP Major facilitator Superfamily
PPHEPGDA_00885 1.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
PPHEPGDA_00886 1.8e-226 yfiU EGP Major facilitator Superfamily
PPHEPGDA_00887 6.6e-18 yfiU EGP Major facilitator Superfamily
PPHEPGDA_00888 4.9e-79 yfiV K transcriptional
PPHEPGDA_00889 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PPHEPGDA_00890 6.7e-176 yfiY P ABC transporter substrate-binding protein
PPHEPGDA_00891 4.3e-56 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00892 7.5e-89 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00893 3.4e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_00894 6.9e-164 yfhB 5.3.3.17 S PhzF family
PPHEPGDA_00895 2.8e-105 yfhC C nitroreductase
PPHEPGDA_00896 2.1e-25 yfhD S YfhD-like protein
PPHEPGDA_00898 5.6e-169 yfhF S nucleoside-diphosphate sugar epimerase
PPHEPGDA_00899 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
PPHEPGDA_00900 9.7e-52 yfhH S Protein of unknown function (DUF1811)
PPHEPGDA_00902 1.6e-208 yfhI EGP Major facilitator Superfamily
PPHEPGDA_00903 6.2e-20 sspK S reproduction
PPHEPGDA_00904 1.3e-44 yfhJ S WVELL protein
PPHEPGDA_00905 1.4e-45 L transposase activity
PPHEPGDA_00906 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00907 9.2e-92 batE T Bacterial SH3 domain homologues
PPHEPGDA_00908 1.7e-50 yfhL S SdpI/YhfL protein family
PPHEPGDA_00909 1.3e-170 yfhM S Alpha beta hydrolase
PPHEPGDA_00910 3.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PPHEPGDA_00911 0.0 yfhO S Bacterial membrane protein YfhO
PPHEPGDA_00912 1.2e-185 yfhP S membrane-bound metal-dependent
PPHEPGDA_00913 2.5e-210 mutY L A G-specific
PPHEPGDA_00914 6.9e-36 yfhS
PPHEPGDA_00915 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_00916 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
PPHEPGDA_00917 4.9e-48 ygaB S YgaB-like protein
PPHEPGDA_00918 1.3e-104 ygaC J Belongs to the UPF0374 family
PPHEPGDA_00919 1.8e-301 ygaD V ABC transporter
PPHEPGDA_00920 3.3e-179 ygaE S Membrane
PPHEPGDA_00921 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PPHEPGDA_00922 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
PPHEPGDA_00923 4e-80 perR P Belongs to the Fur family
PPHEPGDA_00924 9.5e-56 ygzB S UPF0295 protein
PPHEPGDA_00925 6.7e-167 ygxA S Nucleotidyltransferase-like
PPHEPGDA_00926 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_00931 7.8e-08
PPHEPGDA_00939 2e-08
PPHEPGDA_00943 1.4e-45 L transposase activity
PPHEPGDA_00944 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00945 5e-142 spo0M S COG4326 Sporulation control protein
PPHEPGDA_00946 1.2e-26
PPHEPGDA_00947 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
PPHEPGDA_00948 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PPHEPGDA_00950 3.5e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PPHEPGDA_00951 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
PPHEPGDA_00952 6.2e-169 ssuA M Sulfonate ABC transporter
PPHEPGDA_00953 8e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PPHEPGDA_00954 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
PPHEPGDA_00956 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PPHEPGDA_00957 1.6e-74 ygaO
PPHEPGDA_00958 4.4e-29 K Transcriptional regulator
PPHEPGDA_00960 9.7e-112 yhzB S B3/4 domain
PPHEPGDA_00961 2.3e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PPHEPGDA_00962 2.4e-175 yhbB S Putative amidase domain
PPHEPGDA_00963 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PPHEPGDA_00964 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_00965 1.4e-45 L transposase activity
PPHEPGDA_00966 6e-109 yhbD K Protein of unknown function (DUF4004)
PPHEPGDA_00967 6.6e-64 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
PPHEPGDA_00968 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
PPHEPGDA_00969 0.0 prkA T Ser protein kinase
PPHEPGDA_00970 2.5e-225 yhbH S Belongs to the UPF0229 family
PPHEPGDA_00971 2.2e-76 yhbI K DNA-binding transcription factor activity
PPHEPGDA_00972 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
PPHEPGDA_00973 2.9e-269 yhcA EGP Major facilitator Superfamily
PPHEPGDA_00974 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
PPHEPGDA_00975 2.8e-37 yhcC
PPHEPGDA_00976 1.5e-53
PPHEPGDA_00977 6.6e-60 yhcF K Transcriptional regulator
PPHEPGDA_00978 8.8e-122 yhcG V ABC transporter, ATP-binding protein
PPHEPGDA_00979 5.5e-164 yhcH V ABC transporter, ATP-binding protein
PPHEPGDA_00980 2.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PPHEPGDA_00981 1e-30 cspB K Cold-shock protein
PPHEPGDA_00982 3.1e-150 metQ M Belongs to the nlpA lipoprotein family
PPHEPGDA_00983 8.4e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
PPHEPGDA_00984 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PPHEPGDA_00985 7.7e-177 A Pre-toxin TG
PPHEPGDA_00986 2.5e-63 S Immunity protein 70
PPHEPGDA_00988 1.6e-16 S Domain of unknown function (DUF4935)
PPHEPGDA_00990 2e-49 L Belongs to the 'phage' integrase family
PPHEPGDA_00993 1.9e-44 yddA
PPHEPGDA_00997 9.5e-168 yddB S Conjugative transposon protein TcpC
PPHEPGDA_00998 2e-39 yddC
PPHEPGDA_00999 6.1e-91 yddD S TcpE family
PPHEPGDA_01000 8.5e-218 yddE S AAA-like domain
PPHEPGDA_01001 1.4e-195 yddE S AAA-like domain
PPHEPGDA_01002 1.4e-53 S Domain of unknown function (DUF1874)
PPHEPGDA_01003 0.0 yddG S maturation of SSU-rRNA
PPHEPGDA_01004 1.2e-185 yddH CBM50 M Lysozyme-like
PPHEPGDA_01005 2.9e-82 yddI
PPHEPGDA_01006 1.8e-39 S Domain of unknown function with cystatin-like fold (DUF4467)
PPHEPGDA_01007 2e-58
PPHEPGDA_01008 5.7e-36
PPHEPGDA_01009 1.2e-39 S Domain of unknown function (DUF4145)
PPHEPGDA_01010 5e-69 S response regulator aspartate phosphatase
PPHEPGDA_01012 1.2e-39 yhcM
PPHEPGDA_01013 2.2e-65 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PPHEPGDA_01014 1.4e-165 yhcP
PPHEPGDA_01015 5.2e-100 yhcQ M Spore coat protein
PPHEPGDA_01016 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
PPHEPGDA_01017 2.3e-102 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
PPHEPGDA_01018 1.3e-170 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPHEPGDA_01019 2.1e-67 yhcU S Family of unknown function (DUF5365)
PPHEPGDA_01020 1.3e-67 yhcV S COG0517 FOG CBS domain
PPHEPGDA_01021 1e-119 yhcW 5.4.2.6 S hydrolase
PPHEPGDA_01022 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PPHEPGDA_01023 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PPHEPGDA_01024 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
PPHEPGDA_01025 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
PPHEPGDA_01026 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PPHEPGDA_01027 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PPHEPGDA_01028 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PPHEPGDA_01029 8.8e-212 yhcY 2.7.13.3 T Histidine kinase
PPHEPGDA_01030 1.9e-110 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_01031 3.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
PPHEPGDA_01032 1.2e-38 yhdB S YhdB-like protein
PPHEPGDA_01033 1.8e-53 yhdC S Protein of unknown function (DUF3889)
PPHEPGDA_01034 4.3e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PPHEPGDA_01035 1e-75 nsrR K Transcriptional regulator
PPHEPGDA_01036 1.5e-238 ygxB M Conserved TM helix
PPHEPGDA_01037 6.3e-276 ycgB S Stage V sporulation protein R
PPHEPGDA_01038 1.4e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
PPHEPGDA_01039 5.3e-128 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PPHEPGDA_01040 3.8e-162 citR K Transcriptional regulator
PPHEPGDA_01041 2.9e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
PPHEPGDA_01042 8.6e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_01043 8.5e-249 yhdG E amino acid
PPHEPGDA_01044 2.8e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PPHEPGDA_01045 1.2e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_01046 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_01047 8.1e-45 yhdK S Sigma-M inhibitor protein
PPHEPGDA_01048 6.6e-201 yhdL S Sigma factor regulator N-terminal
PPHEPGDA_01049 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_01050 5.7e-191 yhdN C Aldo keto reductase
PPHEPGDA_01051 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PPHEPGDA_01052 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PPHEPGDA_01053 4.1e-74 cueR K transcriptional
PPHEPGDA_01054 6.4e-73 yhdR 2.6.1.1 E Aminotransferase
PPHEPGDA_01055 1.9e-135 yhdR 2.6.1.1 E Aminotransferase
PPHEPGDA_01056 6.6e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
PPHEPGDA_01057 4.9e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PPHEPGDA_01058 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PPHEPGDA_01059 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PPHEPGDA_01061 5.6e-203 yhdY M Mechanosensitive ion channel
PPHEPGDA_01062 7.2e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
PPHEPGDA_01063 2.4e-145 yheN G deacetylase
PPHEPGDA_01064 1.2e-152 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
PPHEPGDA_01065 5.7e-226 nhaC C Na H antiporter
PPHEPGDA_01066 1.5e-83 nhaX T Belongs to the universal stress protein A family
PPHEPGDA_01067 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
PPHEPGDA_01068 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
PPHEPGDA_01069 4.5e-109 yheG GM NAD(P)H-binding
PPHEPGDA_01070 6.3e-28 sspB S spore protein
PPHEPGDA_01071 1.3e-36 yheE S Family of unknown function (DUF5342)
PPHEPGDA_01072 6.3e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
PPHEPGDA_01073 1.6e-215 yheC HJ YheC/D like ATP-grasp
PPHEPGDA_01074 6.3e-202 yheB S Belongs to the UPF0754 family
PPHEPGDA_01075 9.5e-48 yheA S Belongs to the UPF0342 family
PPHEPGDA_01076 7.5e-205 yhaZ L DNA alkylation repair enzyme
PPHEPGDA_01077 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
PPHEPGDA_01078 1.9e-291 hemZ H coproporphyrinogen III oxidase
PPHEPGDA_01079 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
PPHEPGDA_01080 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
PPHEPGDA_01082 6.7e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
PPHEPGDA_01083 7e-26 S YhzD-like protein
PPHEPGDA_01084 5.2e-167 yhaQ S ABC transporter, ATP-binding protein
PPHEPGDA_01085 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
PPHEPGDA_01086 2.6e-225 yhaO L DNA repair exonuclease
PPHEPGDA_01087 0.0 yhaN L AAA domain
PPHEPGDA_01088 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
PPHEPGDA_01089 1.6e-21 yhaL S Sporulation protein YhaL
PPHEPGDA_01090 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PPHEPGDA_01091 1.5e-89 yhaK S Putative zincin peptidase
PPHEPGDA_01092 2.2e-54 yhaI S Protein of unknown function (DUF1878)
PPHEPGDA_01093 1e-113 hpr K Negative regulator of protease production and sporulation
PPHEPGDA_01094 7e-39 yhaH S YtxH-like protein
PPHEPGDA_01095 3.6e-80 trpP S Tryptophan transporter TrpP
PPHEPGDA_01096 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PPHEPGDA_01097 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PPHEPGDA_01098 4.6e-137 ecsA V transporter (ATP-binding protein)
PPHEPGDA_01099 9.2e-215 ecsB U ABC transporter
PPHEPGDA_01100 6.9e-114 ecsC S EcsC protein family
PPHEPGDA_01101 2.4e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PPHEPGDA_01102 1.4e-243 yhfA C membrane
PPHEPGDA_01103 1.6e-33 1.15.1.2 C Rubrerythrin
PPHEPGDA_01104 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
PPHEPGDA_01105 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPHEPGDA_01106 2.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PPHEPGDA_01107 1.8e-178 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PPHEPGDA_01108 3.8e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
PPHEPGDA_01109 5.4e-101 yhgD K Transcriptional regulator
PPHEPGDA_01110 7.8e-215 yhgE S YhgE Pip N-terminal domain protein
PPHEPGDA_01111 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PPHEPGDA_01112 3.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
PPHEPGDA_01114 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
PPHEPGDA_01115 4.1e-71 3.4.13.21 S ASCH
PPHEPGDA_01116 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
PPHEPGDA_01117 6.4e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
PPHEPGDA_01118 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
PPHEPGDA_01119 1.9e-110 yhfK GM NmrA-like family
PPHEPGDA_01120 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PPHEPGDA_01121 1.9e-65 yhfM
PPHEPGDA_01122 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
PPHEPGDA_01123 8e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
PPHEPGDA_01124 4.3e-77 VY92_01935 K acetyltransferase
PPHEPGDA_01125 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
PPHEPGDA_01126 9.3e-154 yfmC M Periplasmic binding protein
PPHEPGDA_01127 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
PPHEPGDA_01128 2.2e-196 vraB 2.3.1.9 I Belongs to the thiolase family
PPHEPGDA_01129 7.6e-277 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
PPHEPGDA_01130 5e-91 bioY S BioY family
PPHEPGDA_01131 2.4e-181 hemAT NT chemotaxis protein
PPHEPGDA_01132 7.4e-97 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PPHEPGDA_01133 6e-120 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PPHEPGDA_01134 8.3e-30 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
PPHEPGDA_01135 2.3e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_01136 1.3e-32 yhzC S IDEAL
PPHEPGDA_01137 4.2e-109 comK K Competence transcription factor
PPHEPGDA_01138 3.5e-163 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_01139 2.8e-39 yhjA S Excalibur calcium-binding domain
PPHEPGDA_01140 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PPHEPGDA_01141 6.9e-27 yhjC S Protein of unknown function (DUF3311)
PPHEPGDA_01142 6.7e-60 yhjD
PPHEPGDA_01143 5.9e-109 yhjE S SNARE associated Golgi protein
PPHEPGDA_01144 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
PPHEPGDA_01145 1.3e-282 yhjG CH FAD binding domain
PPHEPGDA_01146 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_01149 4.2e-212 glcP G Major Facilitator Superfamily
PPHEPGDA_01150 1.2e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
PPHEPGDA_01151 2e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
PPHEPGDA_01152 1e-251 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
PPHEPGDA_01153 3.8e-187 yhjM 5.1.1.1 K Transcriptional regulator
PPHEPGDA_01154 4.2e-201 abrB S membrane
PPHEPGDA_01155 9.6e-209 EGP Transmembrane secretion effector
PPHEPGDA_01156 0.0 S Sugar transport-related sRNA regulator N-term
PPHEPGDA_01157 2.2e-78 yhjR S Rubrerythrin
PPHEPGDA_01158 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
PPHEPGDA_01159 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PPHEPGDA_01160 1e-218 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PPHEPGDA_01161 0.0 sbcC L COG0419 ATPase involved in DNA repair
PPHEPGDA_01162 1.1e-49 yisB V COG1403 Restriction endonuclease
PPHEPGDA_01163 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
PPHEPGDA_01164 7.5e-65 gerPE S Spore germination protein GerPE
PPHEPGDA_01165 3.1e-23 gerPD S Spore germination protein
PPHEPGDA_01166 1.8e-54 gerPC S Spore germination protein
PPHEPGDA_01167 4e-34 gerPB S cell differentiation
PPHEPGDA_01168 1.9e-33 gerPA S Spore germination protein
PPHEPGDA_01169 5.7e-22 yisI S Spo0E like sporulation regulatory protein
PPHEPGDA_01170 9.1e-175 cotH M Spore Coat
PPHEPGDA_01171 1.6e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
PPHEPGDA_01172 3e-57 yisL S UPF0344 protein
PPHEPGDA_01173 0.0 wprA O Belongs to the peptidase S8 family
PPHEPGDA_01174 1.5e-100 yisN S Protein of unknown function (DUF2777)
PPHEPGDA_01175 0.0 asnO 6.3.5.4 E Asparagine synthase
PPHEPGDA_01176 1.6e-111 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
PPHEPGDA_01177 4e-243 yisQ V Mate efflux family protein
PPHEPGDA_01178 1.2e-160 yisR K Transcriptional regulator
PPHEPGDA_01179 5.8e-183 purR K helix_turn _helix lactose operon repressor
PPHEPGDA_01180 1.9e-189 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
PPHEPGDA_01181 7e-92 yisT S DinB family
PPHEPGDA_01182 2.7e-106 argO S Lysine exporter protein LysE YggA
PPHEPGDA_01183 2.4e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PPHEPGDA_01184 2e-35 mcbG S Pentapeptide repeats (9 copies)
PPHEPGDA_01185 2.7e-154 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PPHEPGDA_01186 1.1e-72 yitH K Acetyltransferase (GNAT) domain
PPHEPGDA_01187 1e-70 yjcF S Acetyltransferase (GNAT) domain
PPHEPGDA_01188 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
PPHEPGDA_01189 5.6e-54 yajQ S Belongs to the UPF0234 family
PPHEPGDA_01190 6.9e-161 cvfB S protein conserved in bacteria
PPHEPGDA_01192 9e-36 yitR S Domain of unknown function (DUF3784)
PPHEPGDA_01193 8.7e-156 yitS S protein conserved in bacteria
PPHEPGDA_01194 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
PPHEPGDA_01195 5e-73 ipi S Intracellular proteinase inhibitor
PPHEPGDA_01196 1.5e-26 S Protein of unknown function (DUF3813)
PPHEPGDA_01198 3.5e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PPHEPGDA_01199 2.1e-140 yjfP S COG1073 Hydrolases of the alpha beta superfamily
PPHEPGDA_01200 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
PPHEPGDA_01201 1.5e-22 pilT S Proteolipid membrane potential modulator
PPHEPGDA_01202 2.7e-266 yitY C D-arabinono-1,4-lactone oxidase
PPHEPGDA_01203 1.7e-88 norB G Major Facilitator Superfamily
PPHEPGDA_01204 1.5e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PPHEPGDA_01205 9.4e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PPHEPGDA_01206 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PPHEPGDA_01207 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PPHEPGDA_01208 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PPHEPGDA_01209 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
PPHEPGDA_01210 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PPHEPGDA_01211 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_01212 1.4e-45 L transposase activity
PPHEPGDA_01213 9.5e-28 yjzC S YjzC-like protein
PPHEPGDA_01214 2.3e-16 yjzD S Protein of unknown function (DUF2929)
PPHEPGDA_01215 6.8e-141 yjaU I carboxylic ester hydrolase activity
PPHEPGDA_01216 1.8e-101 yjaV
PPHEPGDA_01217 3.2e-183 med S Transcriptional activator protein med
PPHEPGDA_01218 4.7e-25 comZ S ComZ
PPHEPGDA_01219 2.7e-22 yjzB
PPHEPGDA_01220 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PPHEPGDA_01221 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PPHEPGDA_01222 7.8e-151 yjaZ O Zn-dependent protease
PPHEPGDA_01223 1.8e-184 appD P Belongs to the ABC transporter superfamily
PPHEPGDA_01224 6.5e-187 appF E Belongs to the ABC transporter superfamily
PPHEPGDA_01225 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
PPHEPGDA_01226 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01227 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01228 8.6e-147 yjbA S Belongs to the UPF0736 family
PPHEPGDA_01229 2.3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PPHEPGDA_01230 0.0 oppA E ABC transporter substrate-binding protein
PPHEPGDA_01231 8.7e-165 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01232 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01233 6.8e-198 oppD P Belongs to the ABC transporter superfamily
PPHEPGDA_01234 5.5e-172 oppF E Belongs to the ABC transporter superfamily
PPHEPGDA_01235 2.8e-211 yjbB EGP Major Facilitator Superfamily
PPHEPGDA_01236 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_01237 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PPHEPGDA_01238 1.7e-111 yjbE P Integral membrane protein TerC family
PPHEPGDA_01239 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PPHEPGDA_01240 2.1e-221 yjbF S Competence protein
PPHEPGDA_01241 0.0 pepF E oligoendopeptidase F
PPHEPGDA_01242 1.8e-20
PPHEPGDA_01243 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PPHEPGDA_01244 3.7e-72 yjbI S Bacterial-like globin
PPHEPGDA_01245 3.5e-68 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PPHEPGDA_01246 1e-99 yjbK S protein conserved in bacteria
PPHEPGDA_01247 7.8e-61 yjbL S Belongs to the UPF0738 family
PPHEPGDA_01248 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
PPHEPGDA_01249 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PPHEPGDA_01250 9.9e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPHEPGDA_01251 5.1e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
PPHEPGDA_01252 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PPHEPGDA_01253 6.4e-136 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PPHEPGDA_01254 1.3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
PPHEPGDA_01255 3.7e-215 thiO 1.4.3.19 E Glycine oxidase
PPHEPGDA_01256 4.4e-29 thiS H thiamine diphosphate biosynthetic process
PPHEPGDA_01257 6.5e-134 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
PPHEPGDA_01258 3.7e-185 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PPHEPGDA_01259 2e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PPHEPGDA_01260 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
PPHEPGDA_01261 5.9e-54 yjbX S Spore coat protein
PPHEPGDA_01262 5.2e-83 cotZ S Spore coat protein
PPHEPGDA_01263 3.4e-96 cotY S Spore coat protein Z
PPHEPGDA_01264 1.4e-38 cotX S Spore Coat Protein X and V domain
PPHEPGDA_01265 1.4e-10 cotW
PPHEPGDA_01266 1.4e-23 cotV S Spore Coat Protein X and V domain
PPHEPGDA_01267 1.9e-56 yjcA S Protein of unknown function (DUF1360)
PPHEPGDA_01270 4.9e-38 spoVIF S Stage VI sporulation protein F
PPHEPGDA_01271 0.0 yjcD 3.6.4.12 L DNA helicase
PPHEPGDA_01272 1.7e-38
PPHEPGDA_01273 8.7e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_01274 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
PPHEPGDA_01275 3.8e-136 yjcH P COG2382 Enterochelin esterase and related enzymes
PPHEPGDA_01276 5.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PPHEPGDA_01277 9.4e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PPHEPGDA_01278 1e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
PPHEPGDA_01279 1.7e-210 yjcL S Protein of unknown function (DUF819)
PPHEPGDA_01281 1.3e-39 L Belongs to the 'phage' integrase family
PPHEPGDA_01282 1e-18 L Belongs to the 'phage' integrase family
PPHEPGDA_01283 1.1e-220 L Transposase
PPHEPGDA_01284 9.9e-119 L PhoH-like protein
PPHEPGDA_01285 1e-33 xkdA E IrrE N-terminal-like domain
PPHEPGDA_01287 2.6e-29 S Protein of unknown function (DUF4064)
PPHEPGDA_01288 2e-49
PPHEPGDA_01289 3.6e-45 xre K Helix-turn-helix XRE-family like proteins
PPHEPGDA_01290 3.7e-15 K Helix-turn-helix XRE-family like proteins
PPHEPGDA_01291 1.4e-07 S Helix-turn-helix domain
PPHEPGDA_01292 9.1e-87
PPHEPGDA_01293 9.6e-50 L COG2963 Transposase and inactivated derivatives
PPHEPGDA_01294 2.5e-61 L Integrase core domain
PPHEPGDA_01295 4.2e-76 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
PPHEPGDA_01296 1.7e-07 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_01297 1.5e-26 K Helix-turn-helix domain
PPHEPGDA_01298 2.7e-09 XK26_06135 M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PPHEPGDA_01301 4.6e-44 G Toxic component of a toxin-antitoxin (TA) module. An RNase
PPHEPGDA_01305 1.2e-107 S aspartate phosphatase
PPHEPGDA_01306 3.8e-270 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PPHEPGDA_01307 2.4e-83 S SMI1-KNR4 cell-wall
PPHEPGDA_01308 1.7e-213 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_01309 6.9e-92 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
PPHEPGDA_01311 4.4e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PPHEPGDA_01312 3.4e-21 S Domain of unknown function (DUF4177)
PPHEPGDA_01313 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
PPHEPGDA_01314 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PPHEPGDA_01316 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
PPHEPGDA_01317 2.1e-82 S Protein of unknown function (DUF2690)
PPHEPGDA_01318 2.3e-20 yjfB S Putative motility protein
PPHEPGDA_01319 1.4e-167 yjfC O Predicted Zn-dependent protease (DUF2268)
PPHEPGDA_01320 1.2e-45 T PhoQ Sensor
PPHEPGDA_01321 9.9e-103 yjgB S Domain of unknown function (DUF4309)
PPHEPGDA_01322 1.6e-293 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
PPHEPGDA_01323 4e-153 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
PPHEPGDA_01324 2.8e-72 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
PPHEPGDA_01325 3.8e-88 yjgD S Protein of unknown function (DUF1641)
PPHEPGDA_01327 1.3e-113 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
PPHEPGDA_01329 7.3e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
PPHEPGDA_01330 8.5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
PPHEPGDA_01331 8.2e-30
PPHEPGDA_01332 4.6e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PPHEPGDA_01333 1.9e-122 ybbM S transport system, permease component
PPHEPGDA_01334 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
PPHEPGDA_01335 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
PPHEPGDA_01336 1.1e-89 yjlB S Cupin domain
PPHEPGDA_01337 7.1e-66 yjlC S Protein of unknown function (DUF1641)
PPHEPGDA_01338 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
PPHEPGDA_01339 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
PPHEPGDA_01340 2.7e-247 yjmB G symporter YjmB
PPHEPGDA_01341 1.4e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
PPHEPGDA_01342 9.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
PPHEPGDA_01343 1.7e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PPHEPGDA_01344 1.1e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_01345 2.4e-226 exuT G Sugar (and other) transporter
PPHEPGDA_01346 1.5e-183 exuR K transcriptional
PPHEPGDA_01347 1.1e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
PPHEPGDA_01348 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
PPHEPGDA_01349 7.4e-130 MA20_18170 S membrane transporter protein
PPHEPGDA_01350 2.3e-78 yjoA S DinB family
PPHEPGDA_01351 3e-212 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
PPHEPGDA_01352 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_01353 1.4e-45 L transposase activity
PPHEPGDA_01354 1e-212 S response regulator aspartate phosphatase
PPHEPGDA_01356 4e-25 S YCII-related domain
PPHEPGDA_01357 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
PPHEPGDA_01358 6.1e-61 yjqA S Bacterial PH domain
PPHEPGDA_01359 1.3e-108 yjqB S Pfam:DUF867
PPHEPGDA_01360 4.4e-160 ydbD P Catalase
PPHEPGDA_01361 1.6e-111 xkdA E IrrE N-terminal-like domain
PPHEPGDA_01362 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
PPHEPGDA_01364 1.9e-155 xkdB K sequence-specific DNA binding
PPHEPGDA_01365 2.4e-118 xkdC L Bacterial dnaA protein
PPHEPGDA_01368 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
PPHEPGDA_01369 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
PPHEPGDA_01370 4.8e-140 xtmA L phage terminase small subunit
PPHEPGDA_01371 1.2e-252 xtmB S phage terminase, large subunit
PPHEPGDA_01372 1.6e-285 yqbA S portal protein
PPHEPGDA_01373 1.7e-132 yqbD 2.1.1.72 L Putative phage serine protease XkdF
PPHEPGDA_01374 5.8e-169 xkdG S Phage capsid family
PPHEPGDA_01375 5.6e-62 yqbG S Protein of unknown function (DUF3199)
PPHEPGDA_01376 8.7e-65 yqbH S Domain of unknown function (DUF3599)
PPHEPGDA_01377 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
PPHEPGDA_01378 1.9e-77 xkdJ
PPHEPGDA_01379 1.6e-255 xkdK S Phage tail sheath C-terminal domain
PPHEPGDA_01380 1.4e-75 xkdM S Phage tail tube protein
PPHEPGDA_01381 2.3e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
PPHEPGDA_01382 1.1e-263 xkdO L Transglycosylase SLT domain
PPHEPGDA_01383 2.3e-117 xkdP S Lysin motif
PPHEPGDA_01384 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
PPHEPGDA_01385 2.1e-39 xkdR S Protein of unknown function (DUF2577)
PPHEPGDA_01386 3.1e-69 xkdS S Protein of unknown function (DUF2634)
PPHEPGDA_01387 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
PPHEPGDA_01388 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
PPHEPGDA_01389 6.7e-41
PPHEPGDA_01390 0.0
PPHEPGDA_01391 2.3e-51 xkdW S XkdW protein
PPHEPGDA_01392 4.2e-22 xkdX
PPHEPGDA_01393 7.5e-152 xepA
PPHEPGDA_01394 2.8e-39 xhlA S Haemolysin XhlA
PPHEPGDA_01395 1.8e-38 xhlB S SPP1 phage holin
PPHEPGDA_01396 1.3e-162 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_01397 6.7e-23 spoIISB S Stage II sporulation protein SB
PPHEPGDA_01398 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
PPHEPGDA_01399 1.9e-173 pit P phosphate transporter
PPHEPGDA_01400 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
PPHEPGDA_01401 6.8e-240 steT E amino acid
PPHEPGDA_01402 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
PPHEPGDA_01403 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PPHEPGDA_01404 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PPHEPGDA_01406 7.5e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PPHEPGDA_01407 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
PPHEPGDA_01408 2.5e-152 dppA E D-aminopeptidase
PPHEPGDA_01409 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01410 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
PPHEPGDA_01411 2.7e-188 dppD P Belongs to the ABC transporter superfamily
PPHEPGDA_01412 0.0 dppE E ABC transporter substrate-binding protein
PPHEPGDA_01414 1.3e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
PPHEPGDA_01415 6.8e-201 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PPHEPGDA_01416 1.8e-167 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PPHEPGDA_01417 1.5e-186 ykfD E Belongs to the ABC transporter superfamily
PPHEPGDA_01418 6.4e-201 pgl 3.1.1.31 G 6-phosphogluconolactonase
PPHEPGDA_01419 2e-160 ykgA E Amidinotransferase
PPHEPGDA_01420 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
PPHEPGDA_01421 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PPHEPGDA_01422 1.5e-09
PPHEPGDA_01423 8.6e-128 ykjA S Protein of unknown function (DUF421)
PPHEPGDA_01424 2.2e-96 ykkA S Protein of unknown function (DUF664)
PPHEPGDA_01425 9.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PPHEPGDA_01426 2.9e-54 ykkC P Multidrug resistance protein
PPHEPGDA_01427 9.1e-50 ykkD P Multidrug resistance protein
PPHEPGDA_01428 1.5e-169 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
PPHEPGDA_01429 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PPHEPGDA_01430 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PPHEPGDA_01431 1.3e-70 ohrA O Organic hydroperoxide resistance protein
PPHEPGDA_01432 4.8e-73 ohrR K COG1846 Transcriptional regulators
PPHEPGDA_01433 2.4e-71 ohrB O Organic hydroperoxide resistance protein
PPHEPGDA_01434 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
PPHEPGDA_01435 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PPHEPGDA_01436 5e-176 isp O Belongs to the peptidase S8 family
PPHEPGDA_01437 3.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PPHEPGDA_01438 5.3e-136 ykoC P Cobalt transport protein
PPHEPGDA_01439 1.6e-302 P ABC transporter, ATP-binding protein
PPHEPGDA_01440 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
PPHEPGDA_01441 5.1e-110 ykoF S YKOF-related Family
PPHEPGDA_01442 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_01443 1.1e-240 ykoH 2.7.13.3 T Histidine kinase
PPHEPGDA_01444 3.1e-69 ykoI S Peptidase propeptide and YPEB domain
PPHEPGDA_01445 4.9e-85 ykoJ S Peptidase propeptide and YPEB domain
PPHEPGDA_01448 3.8e-222 mgtE P Acts as a magnesium transporter
PPHEPGDA_01449 1.4e-53 tnrA K transcriptional
PPHEPGDA_01450 5.9e-18
PPHEPGDA_01451 6.9e-26 ykoL
PPHEPGDA_01452 1.3e-81 mhqR K transcriptional
PPHEPGDA_01453 4.4e-216 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
PPHEPGDA_01454 1.1e-93 ykoP G polysaccharide deacetylase
PPHEPGDA_01455 6.6e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
PPHEPGDA_01456 0.0 ykoS
PPHEPGDA_01457 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PPHEPGDA_01458 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
PPHEPGDA_01459 1.4e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PPHEPGDA_01460 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
PPHEPGDA_01461 2.7e-109 ykoX S membrane-associated protein
PPHEPGDA_01462 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
PPHEPGDA_01463 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_01464 1.7e-109 rsgI S Anti-sigma factor N-terminus
PPHEPGDA_01465 1.9e-26 sspD S small acid-soluble spore protein
PPHEPGDA_01466 1.5e-124 ykrK S Domain of unknown function (DUF1836)
PPHEPGDA_01467 3.5e-155 htpX O Belongs to the peptidase M48B family
PPHEPGDA_01468 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
PPHEPGDA_01469 1.2e-10 ydfR S Protein of unknown function (DUF421)
PPHEPGDA_01470 4.1e-18 ykzE
PPHEPGDA_01471 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
PPHEPGDA_01472 0.0 kinE 2.7.13.3 T Histidine kinase
PPHEPGDA_01473 5e-87 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PPHEPGDA_01475 1.3e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
PPHEPGDA_01476 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
PPHEPGDA_01477 4.2e-149 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PPHEPGDA_01478 1.1e-231 mtnE 2.6.1.83 E Aminotransferase
PPHEPGDA_01479 3.4e-230 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
PPHEPGDA_01480 1.9e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
PPHEPGDA_01481 5.2e-113 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
PPHEPGDA_01482 4.1e-95 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
PPHEPGDA_01483 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
PPHEPGDA_01484 6.4e-09 S Spo0E like sporulation regulatory protein
PPHEPGDA_01485 3.7e-52 eag
PPHEPGDA_01486 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
PPHEPGDA_01487 1.3e-75 ykvE K transcriptional
PPHEPGDA_01488 6.9e-123 motB N Flagellar motor protein
PPHEPGDA_01489 5.1e-137 motA N flagellar motor
PPHEPGDA_01490 0.0 clpE O Belongs to the ClpA ClpB family
PPHEPGDA_01491 1.8e-179 ykvI S membrane
PPHEPGDA_01492 2.3e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PPHEPGDA_01493 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PPHEPGDA_01494 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PPHEPGDA_01495 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PPHEPGDA_01496 7.6e-61 ykvN K HxlR-like helix-turn-helix
PPHEPGDA_01497 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_01498 7.7e-27 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_01499 1.3e-45
PPHEPGDA_01500 9e-254 I Pfam Lipase (class 3)
PPHEPGDA_01501 2.7e-41 S Protein of unknown function (DUF1433)
PPHEPGDA_01502 3.9e-27 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
PPHEPGDA_01503 2.2e-11
PPHEPGDA_01505 1.8e-83 2.7.7.49 L reverse transcriptase
PPHEPGDA_01506 3.7e-76 G Glycosyl hydrolases family 18
PPHEPGDA_01507 1.1e-44 ykvR S Protein of unknown function (DUF3219)
PPHEPGDA_01508 6e-25 ykvS S protein conserved in bacteria
PPHEPGDA_01509 2.8e-28
PPHEPGDA_01510 3.5e-101 ykvT 3.5.1.28 M Cell Wall Hydrolase
PPHEPGDA_01511 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_01512 9.2e-89 stoA CO thiol-disulfide
PPHEPGDA_01513 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PPHEPGDA_01514 2.3e-09
PPHEPGDA_01515 7.4e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PPHEPGDA_01516 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
PPHEPGDA_01518 7.6e-128 glcT K antiterminator
PPHEPGDA_01519 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_01520 2.1e-39 ptsH G phosphocarrier protein HPr
PPHEPGDA_01521 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PPHEPGDA_01522 7.2e-39 splA S Transcriptional regulator
PPHEPGDA_01523 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
PPHEPGDA_01524 7e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_01525 8.2e-258 mcpC NT chemotaxis protein
PPHEPGDA_01526 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
PPHEPGDA_01527 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_01528 3e-123 ykwD J protein with SCP PR1 domains
PPHEPGDA_01529 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
PPHEPGDA_01530 0.0 pilS 2.7.13.3 T Histidine kinase
PPHEPGDA_01531 2e-222 patA 2.6.1.1 E Aminotransferase
PPHEPGDA_01532 2.2e-15
PPHEPGDA_01533 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
PPHEPGDA_01534 1.7e-84 ykyB S YkyB-like protein
PPHEPGDA_01535 9.9e-236 ykuC EGP Major facilitator Superfamily
PPHEPGDA_01536 1.8e-87 ykuD S protein conserved in bacteria
PPHEPGDA_01537 9.4e-166 ykuE S Metallophosphoesterase
PPHEPGDA_01538 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_01539 5.2e-234 ykuI T Diguanylate phosphodiesterase
PPHEPGDA_01540 3.9e-37 ykuJ S protein conserved in bacteria
PPHEPGDA_01541 4.4e-94 ykuK S Ribonuclease H-like
PPHEPGDA_01542 3.9e-27 ykzF S Antirepressor AbbA
PPHEPGDA_01543 1.8e-75 ykuL S CBS domain
PPHEPGDA_01544 1.8e-167 ccpC K Transcriptional regulator
PPHEPGDA_01545 3.7e-87 fld C Flavodoxin domain
PPHEPGDA_01546 1.5e-174 ykuO
PPHEPGDA_01547 8.7e-78 fld C Flavodoxin
PPHEPGDA_01548 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PPHEPGDA_01549 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PPHEPGDA_01550 9e-37 ykuS S Belongs to the UPF0180 family
PPHEPGDA_01551 8.8e-142 ykuT M Mechanosensitive ion channel
PPHEPGDA_01552 3.9e-101 ykuU O Alkyl hydroperoxide reductase
PPHEPGDA_01553 1.4e-80 ykuV CO thiol-disulfide
PPHEPGDA_01554 5.8e-95 rok K Repressor of ComK
PPHEPGDA_01555 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_01556 1.4e-45 L transposase activity
PPHEPGDA_01557 1e-144 yknT
PPHEPGDA_01558 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
PPHEPGDA_01559 2e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
PPHEPGDA_01560 1.2e-244 moeA 2.10.1.1 H molybdopterin
PPHEPGDA_01561 1.1e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
PPHEPGDA_01562 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
PPHEPGDA_01563 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
PPHEPGDA_01564 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
PPHEPGDA_01565 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
PPHEPGDA_01566 1e-117 yknW S Yip1 domain
PPHEPGDA_01567 3.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PPHEPGDA_01568 9.4e-124 macB V ABC transporter, ATP-binding protein
PPHEPGDA_01569 2.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
PPHEPGDA_01570 3.1e-136 fruR K Transcriptional regulator
PPHEPGDA_01571 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
PPHEPGDA_01572 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
PPHEPGDA_01573 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PPHEPGDA_01574 8.1e-39 ykoA
PPHEPGDA_01575 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
PPHEPGDA_01576 1.3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PPHEPGDA_01577 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PPHEPGDA_01578 1.1e-12 S Uncharacterized protein YkpC
PPHEPGDA_01579 7.7e-183 mreB D Rod-share determining protein MreBH
PPHEPGDA_01580 1.5e-43 abrB K of stationary sporulation gene expression
PPHEPGDA_01581 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
PPHEPGDA_01582 1.4e-147 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
PPHEPGDA_01583 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
PPHEPGDA_01584 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PPHEPGDA_01585 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPHEPGDA_01586 8.2e-31 ykzG S Belongs to the UPF0356 family
PPHEPGDA_01587 4.2e-147 ykrA S hydrolases of the HAD superfamily
PPHEPGDA_01588 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPHEPGDA_01590 2e-115 recN L Putative cell-wall binding lipoprotein
PPHEPGDA_01591 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PPHEPGDA_01592 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PPHEPGDA_01593 2.2e-230 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PPHEPGDA_01594 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PPHEPGDA_01595 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
PPHEPGDA_01596 1e-276 speA 4.1.1.19 E Arginine
PPHEPGDA_01597 1.7e-41 yktA S Belongs to the UPF0223 family
PPHEPGDA_01598 4.6e-117 yktB S Belongs to the UPF0637 family
PPHEPGDA_01599 7.1e-26 ykzI
PPHEPGDA_01600 4.3e-149 suhB 3.1.3.25 G Inositol monophosphatase
PPHEPGDA_01601 3.8e-76 ykzC S Acetyltransferase (GNAT) family
PPHEPGDA_01602 3.5e-171 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
PPHEPGDA_01603 3.7e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
PPHEPGDA_01604 0.0 ylaA
PPHEPGDA_01605 2.7e-42 ylaB
PPHEPGDA_01606 8e-39 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_01607 1.6e-11 sigC S Putative zinc-finger
PPHEPGDA_01608 1.8e-38 ylaE
PPHEPGDA_01609 8.2e-22 S Family of unknown function (DUF5325)
PPHEPGDA_01610 0.0 typA T GTP-binding protein TypA
PPHEPGDA_01611 4.2e-47 ylaH S YlaH-like protein
PPHEPGDA_01612 2.5e-32 ylaI S protein conserved in bacteria
PPHEPGDA_01613 3.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PPHEPGDA_01614 1.2e-247 phoH T ATPase related to phosphate starvation-inducible protein PhoH
PPHEPGDA_01615 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
PPHEPGDA_01616 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
PPHEPGDA_01617 8.7e-44 ylaN S Belongs to the UPF0358 family
PPHEPGDA_01618 3.6e-211 ftsW D Belongs to the SEDS family
PPHEPGDA_01619 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PPHEPGDA_01620 4.2e-164 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
PPHEPGDA_01621 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
PPHEPGDA_01622 1.5e-189 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
PPHEPGDA_01623 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PPHEPGDA_01624 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
PPHEPGDA_01625 1.2e-52 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
PPHEPGDA_01626 7e-164 ctaG S cytochrome c oxidase
PPHEPGDA_01627 7e-62 ylbA S YugN-like family
PPHEPGDA_01628 4.4e-74 ylbB T COG0517 FOG CBS domain
PPHEPGDA_01629 4.3e-200 ylbC S protein with SCP PR1 domains
PPHEPGDA_01630 4.1e-63 ylbD S Putative coat protein
PPHEPGDA_01631 6.7e-37 ylbE S YlbE-like protein
PPHEPGDA_01632 1.8e-75 ylbF S Belongs to the UPF0342 family
PPHEPGDA_01633 2.9e-38 ylbG S UPF0298 protein
PPHEPGDA_01634 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
PPHEPGDA_01635 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PPHEPGDA_01636 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
PPHEPGDA_01637 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
PPHEPGDA_01638 6.8e-187 ylbL T Belongs to the peptidase S16 family
PPHEPGDA_01639 4.3e-228 ylbM S Belongs to the UPF0348 family
PPHEPGDA_01641 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
PPHEPGDA_01642 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PPHEPGDA_01643 7.5e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
PPHEPGDA_01644 1.5e-88 ylbP K n-acetyltransferase
PPHEPGDA_01645 1.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PPHEPGDA_01646 3e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PPHEPGDA_01647 2.9e-78 mraZ K Belongs to the MraZ family
PPHEPGDA_01648 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PPHEPGDA_01649 3.7e-44 ftsL D Essential cell division protein
PPHEPGDA_01650 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PPHEPGDA_01651 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
PPHEPGDA_01652 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PPHEPGDA_01653 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PPHEPGDA_01654 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PPHEPGDA_01655 5.7e-186 spoVE D Belongs to the SEDS family
PPHEPGDA_01656 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PPHEPGDA_01657 5.3e-167 murB 1.3.1.98 M cell wall formation
PPHEPGDA_01658 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PPHEPGDA_01659 2.4e-103 ylxW S protein conserved in bacteria
PPHEPGDA_01660 5.1e-102 ylxX S protein conserved in bacteria
PPHEPGDA_01661 6.2e-58 sbp S small basic protein
PPHEPGDA_01662 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PPHEPGDA_01663 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PPHEPGDA_01664 0.0 bpr O COG1404 Subtilisin-like serine proteases
PPHEPGDA_01666 6.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
PPHEPGDA_01667 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_01668 1.4e-139 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_01669 9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
PPHEPGDA_01670 2.6e-252 argE 3.5.1.16 E Acetylornithine deacetylase
PPHEPGDA_01671 2.4e-37 ylmC S sporulation protein
PPHEPGDA_01672 2e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
PPHEPGDA_01673 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PPHEPGDA_01674 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PPHEPGDA_01675 1.6e-39 yggT S membrane
PPHEPGDA_01676 8.2e-137 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
PPHEPGDA_01677 2.6e-67 divIVA D Cell division initiation protein
PPHEPGDA_01678 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PPHEPGDA_01679 1.5e-134 L Integrase core domain
PPHEPGDA_01680 6e-44 tnpIS3 L Transposase
PPHEPGDA_01681 3.8e-63 dksA T COG1734 DnaK suppressor protein
PPHEPGDA_01682 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PPHEPGDA_01683 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PPHEPGDA_01684 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PPHEPGDA_01685 7.9e-228 pyrP F Xanthine uracil
PPHEPGDA_01686 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PPHEPGDA_01687 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PPHEPGDA_01688 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PPHEPGDA_01689 0.0 carB 6.3.5.5 F Belongs to the CarB family
PPHEPGDA_01690 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PPHEPGDA_01691 6.6e-173 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PPHEPGDA_01692 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PPHEPGDA_01693 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PPHEPGDA_01694 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
PPHEPGDA_01695 4.1e-179 cysP P phosphate transporter
PPHEPGDA_01696 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
PPHEPGDA_01697 2.1e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
PPHEPGDA_01698 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
PPHEPGDA_01699 3.8e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
PPHEPGDA_01700 1.6e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
PPHEPGDA_01701 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PPHEPGDA_01702 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
PPHEPGDA_01703 2.4e-156 yloC S stress-induced protein
PPHEPGDA_01704 1.5e-40 ylzA S Belongs to the UPF0296 family
PPHEPGDA_01705 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PPHEPGDA_01706 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PPHEPGDA_01707 8.2e-224 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PPHEPGDA_01708 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PPHEPGDA_01709 7.3e-83 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PPHEPGDA_01710 2.6e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PPHEPGDA_01711 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PPHEPGDA_01712 2.6e-205 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PPHEPGDA_01713 2.3e-139 stp 3.1.3.16 T phosphatase
PPHEPGDA_01714 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
PPHEPGDA_01715 7.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PPHEPGDA_01716 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PPHEPGDA_01717 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
PPHEPGDA_01718 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PPHEPGDA_01719 5.5e-59 asp S protein conserved in bacteria
PPHEPGDA_01720 2.1e-299 yloV S kinase related to dihydroxyacetone kinase
PPHEPGDA_01721 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
PPHEPGDA_01722 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
PPHEPGDA_01723 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PPHEPGDA_01724 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
PPHEPGDA_01725 9.5e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PPHEPGDA_01726 1e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
PPHEPGDA_01727 2.3e-128 IQ reductase
PPHEPGDA_01728 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PPHEPGDA_01729 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PPHEPGDA_01730 0.0 smc D Required for chromosome condensation and partitioning
PPHEPGDA_01731 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PPHEPGDA_01732 2.9e-87
PPHEPGDA_01733 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PPHEPGDA_01734 2.3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PPHEPGDA_01735 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PPHEPGDA_01736 4.5e-36 ylqC S Belongs to the UPF0109 family
PPHEPGDA_01737 6.3e-61 ylqD S YlqD protein
PPHEPGDA_01738 1.5e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PPHEPGDA_01739 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PPHEPGDA_01740 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PPHEPGDA_01741 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PPHEPGDA_01742 6.9e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPHEPGDA_01743 9.2e-282 ylqG
PPHEPGDA_01744 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
PPHEPGDA_01745 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PPHEPGDA_01746 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PPHEPGDA_01747 6.8e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
PPHEPGDA_01748 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PPHEPGDA_01749 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PPHEPGDA_01750 2.2e-168 xerC L tyrosine recombinase XerC
PPHEPGDA_01751 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PPHEPGDA_01752 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PPHEPGDA_01753 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PPHEPGDA_01754 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
PPHEPGDA_01755 2e-74 flgC N Belongs to the flagella basal body rod proteins family
PPHEPGDA_01756 1.9e-31 fliE N Flagellar hook-basal body
PPHEPGDA_01757 7.7e-254 fliF N The M ring may be actively involved in energy transduction
PPHEPGDA_01758 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PPHEPGDA_01759 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
PPHEPGDA_01760 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
PPHEPGDA_01761 1.5e-69 fliJ N Flagellar biosynthesis chaperone
PPHEPGDA_01762 1.3e-36 ylxF S MgtE intracellular N domain
PPHEPGDA_01763 1.7e-215 fliK N Flagellar hook-length control protein
PPHEPGDA_01764 2.3e-72 flgD N Flagellar basal body rod modification protein
PPHEPGDA_01765 1.8e-139 flgG N Flagellar basal body rod
PPHEPGDA_01766 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
PPHEPGDA_01767 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
PPHEPGDA_01768 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
PPHEPGDA_01769 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
PPHEPGDA_01770 2.1e-96 fliZ N Flagellar biosynthesis protein, FliO
PPHEPGDA_01771 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
PPHEPGDA_01772 2.2e-36 fliQ N Role in flagellar biosynthesis
PPHEPGDA_01773 3.6e-132 fliR N Flagellar biosynthetic protein FliR
PPHEPGDA_01774 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PPHEPGDA_01775 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
PPHEPGDA_01776 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
PPHEPGDA_01777 2.8e-157 flhG D Belongs to the ParA family
PPHEPGDA_01778 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
PPHEPGDA_01779 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
PPHEPGDA_01780 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
PPHEPGDA_01781 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
PPHEPGDA_01782 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
PPHEPGDA_01783 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_01784 1.3e-77 ylxL
PPHEPGDA_01785 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
PPHEPGDA_01786 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PPHEPGDA_01787 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PPHEPGDA_01788 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PPHEPGDA_01789 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PPHEPGDA_01790 5.9e-138 cdsA 2.7.7.41 S Belongs to the CDS family
PPHEPGDA_01791 1.3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PPHEPGDA_01792 7.7e-233 rasP M zinc metalloprotease
PPHEPGDA_01793 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PPHEPGDA_01794 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PPHEPGDA_01795 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
PPHEPGDA_01796 1.1e-203 nusA K Participates in both transcription termination and antitermination
PPHEPGDA_01797 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
PPHEPGDA_01798 3.1e-47 ylxQ J ribosomal protein
PPHEPGDA_01799 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PPHEPGDA_01800 3.9e-44 ylxP S protein conserved in bacteria
PPHEPGDA_01801 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PPHEPGDA_01802 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PPHEPGDA_01803 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PPHEPGDA_01804 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PPHEPGDA_01805 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PPHEPGDA_01806 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
PPHEPGDA_01807 4.4e-233 pepR S Belongs to the peptidase M16 family
PPHEPGDA_01808 2.6e-42 ymxH S YlmC YmxH family
PPHEPGDA_01809 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
PPHEPGDA_01810 8.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
PPHEPGDA_01811 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PPHEPGDA_01812 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PPHEPGDA_01813 4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PPHEPGDA_01814 1.6e-307 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PPHEPGDA_01815 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
PPHEPGDA_01816 4.4e-32 S YlzJ-like protein
PPHEPGDA_01817 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PPHEPGDA_01818 1.4e-133 ymfC K Transcriptional regulator
PPHEPGDA_01819 3.8e-205 ymfD EGP Major facilitator Superfamily
PPHEPGDA_01820 3.5e-233 ymfF S Peptidase M16
PPHEPGDA_01821 1.4e-242 ymfH S zinc protease
PPHEPGDA_01822 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
PPHEPGDA_01823 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
PPHEPGDA_01824 2.7e-143 ymfK S Protein of unknown function (DUF3388)
PPHEPGDA_01825 5.5e-124 ymfM S protein conserved in bacteria
PPHEPGDA_01826 5.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PPHEPGDA_01827 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
PPHEPGDA_01828 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PPHEPGDA_01829 2e-211 pbpX V Beta-lactamase
PPHEPGDA_01830 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
PPHEPGDA_01831 5.5e-152 ymdB S protein conserved in bacteria
PPHEPGDA_01832 1.2e-36 spoVS S Stage V sporulation protein S
PPHEPGDA_01833 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
PPHEPGDA_01834 1.4e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PPHEPGDA_01835 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PPHEPGDA_01836 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PPHEPGDA_01837 2.2e-88 cotE S Spore coat protein
PPHEPGDA_01838 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PPHEPGDA_01839 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PPHEPGDA_01844 9.4e-23 wecC 1.1.1.336 M ArpU family transcriptional regulator
PPHEPGDA_01845 8.9e-45 L Phage integrase family
PPHEPGDA_01852 5.9e-64 S HNH endonuclease
PPHEPGDA_01853 3.8e-08
PPHEPGDA_01854 4.6e-70 S Phage terminase, small subunit
PPHEPGDA_01855 4.6e-08 S Terminase
PPHEPGDA_01856 1.7e-213 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_01857 9.9e-69 S Regulatory protein YrvL
PPHEPGDA_01858 3e-96 ymcC S Membrane
PPHEPGDA_01859 3.3e-104 pksA K Transcriptional regulator
PPHEPGDA_01860 4.4e-61 ymzB
PPHEPGDA_01861 1.9e-163 ymaE S Metallo-beta-lactamase superfamily
PPHEPGDA_01862 4.3e-250 aprX O Belongs to the peptidase S8 family
PPHEPGDA_01863 1.9e-07 K Transcriptional regulator
PPHEPGDA_01864 2.1e-126 ymaC S Replication protein
PPHEPGDA_01865 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
PPHEPGDA_01866 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
PPHEPGDA_01867 1.4e-50 ebrA P Small Multidrug Resistance protein
PPHEPGDA_01869 2.1e-46 ymaF S YmaF family
PPHEPGDA_01870 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PPHEPGDA_01871 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
PPHEPGDA_01872 8.2e-23
PPHEPGDA_01873 4.5e-22 ymzA
PPHEPGDA_01874 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
PPHEPGDA_01875 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPHEPGDA_01876 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PPHEPGDA_01877 2e-109 ymaB
PPHEPGDA_01878 1.5e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_01879 1.7e-176 spoVK O stage V sporulation protein K
PPHEPGDA_01880 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PPHEPGDA_01881 3.7e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
PPHEPGDA_01882 1.1e-68 glnR K transcriptional
PPHEPGDA_01883 1e-259 glnA 6.3.1.2 E glutamine synthetase
PPHEPGDA_01884 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_01885 2.8e-24
PPHEPGDA_01886 2.2e-40
PPHEPGDA_01887 1.6e-247 M nucleic acid phosphodiester bond hydrolysis
PPHEPGDA_01889 9.1e-09
PPHEPGDA_01890 2.7e-32
PPHEPGDA_01891 6.2e-85
PPHEPGDA_01892 8.4e-25
PPHEPGDA_01893 9.9e-119 L PhoH-like protein
PPHEPGDA_01894 1.1e-220 L Transposase
PPHEPGDA_01895 1.5e-89 G SMI1-KNR4 cell-wall
PPHEPGDA_01896 2.5e-40 ynaC
PPHEPGDA_01897 7.6e-63 ynaC
PPHEPGDA_01898 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_01899 4.1e-11 S Protein of unknown function (DUF1433)
PPHEPGDA_01900 2e-97 ynaD J Acetyltransferase (GNAT) domain
PPHEPGDA_01902 4.7e-75 S CAAX protease self-immunity
PPHEPGDA_01903 4.7e-08 S Uncharacterised protein family (UPF0715)
PPHEPGDA_01904 5.5e-20 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_01906 3e-79 ynaE S Domain of unknown function (DUF3885)
PPHEPGDA_01907 1.5e-14 ynaF
PPHEPGDA_01909 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
PPHEPGDA_01910 7.9e-255 xynT G MFS/sugar transport protein
PPHEPGDA_01911 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_01912 6.8e-212 xylR GK ROK family
PPHEPGDA_01913 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PPHEPGDA_01914 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
PPHEPGDA_01915 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
PPHEPGDA_01916 1.6e-255 iolT EGP Major facilitator Superfamily
PPHEPGDA_01917 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PPHEPGDA_01919 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
PPHEPGDA_01920 5.2e-15
PPHEPGDA_01923 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PPHEPGDA_01925 8.9e-128 S Domain of unknown function, YrpD
PPHEPGDA_01928 7.9e-25 tatA U protein secretion
PPHEPGDA_01929 1.8e-71
PPHEPGDA_01930 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
PPHEPGDA_01933 2.8e-52 gerAA EG Spore germination protein
PPHEPGDA_01934 1.8e-146 gerAA EG Spore germination protein
PPHEPGDA_01935 3.4e-88 gerLC S Spore germination protein
PPHEPGDA_01936 2.1e-151 yndG S DoxX-like family
PPHEPGDA_01937 8e-114 yndH S Domain of unknown function (DUF4166)
PPHEPGDA_01938 1.6e-307 yndJ S YndJ-like protein
PPHEPGDA_01941 1.5e-135 yndL S Replication protein
PPHEPGDA_01942 6.4e-73 yndM S Protein of unknown function (DUF2512)
PPHEPGDA_01943 2.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
PPHEPGDA_01944 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PPHEPGDA_01945 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
PPHEPGDA_01946 5e-111 yneB L resolvase
PPHEPGDA_01947 1.3e-32 ynzC S UPF0291 protein
PPHEPGDA_01948 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PPHEPGDA_01949 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
PPHEPGDA_01950 1.8e-28 yneF S UPF0154 protein
PPHEPGDA_01951 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
PPHEPGDA_01952 7.1e-127 ccdA O cytochrome c biogenesis protein
PPHEPGDA_01953 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
PPHEPGDA_01954 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
PPHEPGDA_01955 4.2e-74 yneK S Protein of unknown function (DUF2621)
PPHEPGDA_01956 1.2e-64 hspX O Spore coat protein
PPHEPGDA_01957 3.9e-19 sspP S Belongs to the SspP family
PPHEPGDA_01958 2.2e-14 sspO S Belongs to the SspO family
PPHEPGDA_01959 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PPHEPGDA_01960 2.7e-91 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PPHEPGDA_01962 3.1e-08 sspN S Small acid-soluble spore protein N family
PPHEPGDA_01963 3.9e-35 tlp S Belongs to the Tlp family
PPHEPGDA_01964 2e-73 yneP S Thioesterase-like superfamily
PPHEPGDA_01965 1.7e-53 yneQ
PPHEPGDA_01966 4.1e-49 yneR S Belongs to the HesB IscA family
PPHEPGDA_01967 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PPHEPGDA_01968 8.6e-69 yccU S CoA-binding protein
PPHEPGDA_01969 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPHEPGDA_01970 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PPHEPGDA_01971 2.3e-12
PPHEPGDA_01972 8.6e-57 ynfC
PPHEPGDA_01973 5.3e-251 agcS E Sodium alanine symporter
PPHEPGDA_01974 3.3e-291 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
PPHEPGDA_01976 4.5e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
PPHEPGDA_01977 8.4e-243 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_01978 6.5e-25 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_01979 2e-79 yngA S membrane
PPHEPGDA_01980 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PPHEPGDA_01981 5.5e-104 yngC S membrane-associated protein
PPHEPGDA_01982 1.1e-231 nrnB S phosphohydrolase (DHH superfamily)
PPHEPGDA_01983 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PPHEPGDA_01984 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PPHEPGDA_01985 2.2e-165 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
PPHEPGDA_01986 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
PPHEPGDA_01987 8.1e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
PPHEPGDA_01988 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PPHEPGDA_01989 1.1e-209 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
PPHEPGDA_01990 5.5e-302 yngK T Glycosyl hydrolase-like 10
PPHEPGDA_01991 3.1e-63 yngL S Protein of unknown function (DUF1360)
PPHEPGDA_01992 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
PPHEPGDA_01993 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_01994 4.4e-272 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
PPHEPGDA_01995 4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
PPHEPGDA_01996 8.7e-246 yoeA V MATE efflux family protein
PPHEPGDA_01997 9.1e-98 yoeB S IseA DL-endopeptidase inhibitor
PPHEPGDA_01999 2.2e-96 L Integrase
PPHEPGDA_02000 3e-34 yoeD G Helix-turn-helix domain
PPHEPGDA_02001 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PPHEPGDA_02002 4.7e-157 gltR1 K Transcriptional regulator
PPHEPGDA_02003 1.9e-186 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
PPHEPGDA_02004 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
PPHEPGDA_02005 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
PPHEPGDA_02006 7.8e-155 gltC K Transcriptional regulator
PPHEPGDA_02007 2.3e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PPHEPGDA_02008 1.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPHEPGDA_02009 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
PPHEPGDA_02010 2.4e-122 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_02011 7.1e-39 yoxC S Bacterial protein of unknown function (DUF948)
PPHEPGDA_02012 3.2e-133 yoxB
PPHEPGDA_02013 2e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PPHEPGDA_02014 1.5e-127 V ABC-2 family transporter protein
PPHEPGDA_02015 4.9e-94 V ABC-2 family transporter protein
PPHEPGDA_02016 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
PPHEPGDA_02017 3e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_02018 5.7e-222 yoaB EGP Major facilitator Superfamily
PPHEPGDA_02019 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_02022 1.4e-45 L transposase activity
PPHEPGDA_02023 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_02024 1.3e-19
PPHEPGDA_02028 1.5e-240 flp V Beta-lactamase
PPHEPGDA_02030 3.9e-10 ywlA S Uncharacterised protein family (UPF0715)
PPHEPGDA_02032 2.6e-52 ynaF
PPHEPGDA_02033 2.7e-101 ynaE S Domain of unknown function (DUF3885)
PPHEPGDA_02034 1.2e-25 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_02035 6.2e-81 yoaW
PPHEPGDA_02036 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
PPHEPGDA_02037 1.5e-76
PPHEPGDA_02038 4.3e-45 yoaQ S Evidence 4 Homologs of previously reported genes of
PPHEPGDA_02039 1.4e-24 yoqW S Belongs to the SOS response-associated peptidase family
PPHEPGDA_02041 3.1e-87 S response regulator aspartate phosphatase
PPHEPGDA_02043 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PPHEPGDA_02044 5.7e-22 Q Methyltransferase
PPHEPGDA_02045 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
PPHEPGDA_02046 6.7e-08 Q Methyltransferase type 11
PPHEPGDA_02047 1.1e-220 L Transposase
PPHEPGDA_02048 9.9e-119 L PhoH-like protein
PPHEPGDA_02049 2.4e-14 Q Methyltransferase domain
PPHEPGDA_02050 3.7e-23 G Major Facilitator Superfamily
PPHEPGDA_02051 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_02052 2.8e-29 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPHEPGDA_02053 1.1e-30 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPHEPGDA_02054 3.8e-39 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPHEPGDA_02055 6.6e-67 S impB/mucB/samB family C-terminal domain
PPHEPGDA_02056 1.9e-09 S YolD-like protein
PPHEPGDA_02057 6.3e-10
PPHEPGDA_02059 1.8e-98 J Acetyltransferase (GNAT) domain
PPHEPGDA_02060 2.7e-100 yokK S SMI1 / KNR4 family
PPHEPGDA_02061 2.3e-78 S SMI1-KNR4 cell-wall
PPHEPGDA_02062 3e-86 S SMI1-KNR4 cell-wall
PPHEPGDA_02063 2.5e-311 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PPHEPGDA_02064 3.7e-102 yokH G SMI1 / KNR4 family
PPHEPGDA_02065 7.8e-274 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
PPHEPGDA_02066 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
PPHEPGDA_02067 7.9e-134 yobQ K helix_turn_helix, arabinose operon control protein
PPHEPGDA_02068 1e-139 yobR 2.3.1.1 J FR47-like protein
PPHEPGDA_02069 2.1e-97 yobS K Transcriptional regulator
PPHEPGDA_02070 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
PPHEPGDA_02071 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
PPHEPGDA_02072 4.8e-171 yobV K WYL domain
PPHEPGDA_02073 6.1e-94 yobW
PPHEPGDA_02074 1e-51 czrA K transcriptional
PPHEPGDA_02075 5.8e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
PPHEPGDA_02076 1.5e-92 yozB S membrane
PPHEPGDA_02077 5.1e-142
PPHEPGDA_02078 1.5e-91 yocC
PPHEPGDA_02079 1.2e-185 yocD 3.4.17.13 V peptidase S66
PPHEPGDA_02080 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
PPHEPGDA_02081 4.6e-197 desK 2.7.13.3 T Histidine kinase
PPHEPGDA_02082 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_02084 6e-112 yocH CBM50 M COG1388 FOG LysM repeat
PPHEPGDA_02085 0.0 recQ 3.6.4.12 L DNA helicase
PPHEPGDA_02086 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PPHEPGDA_02087 7.4e-83 dksA T general stress protein
PPHEPGDA_02088 8.4e-54 yocL
PPHEPGDA_02089 2e-30
PPHEPGDA_02090 7e-86 yocM O Belongs to the small heat shock protein (HSP20) family
PPHEPGDA_02091 1.1e-40 yozN
PPHEPGDA_02092 1.9e-36 yocN
PPHEPGDA_02093 4.2e-56 yozO S Bacterial PH domain
PPHEPGDA_02094 2.7e-31 yozC
PPHEPGDA_02095 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
PPHEPGDA_02096 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
PPHEPGDA_02097 9.6e-129 sodA 1.15.1.1 P Superoxide dismutase
PPHEPGDA_02098 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
PPHEPGDA_02099 5.6e-167 yocS S -transporter
PPHEPGDA_02100 9.4e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
PPHEPGDA_02101 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
PPHEPGDA_02102 0.0 yojO P Von Willebrand factor
PPHEPGDA_02103 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
PPHEPGDA_02104 5e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
PPHEPGDA_02105 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
PPHEPGDA_02106 5e-229 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
PPHEPGDA_02107 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PPHEPGDA_02109 4.2e-245 norM V Multidrug efflux pump
PPHEPGDA_02110 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PPHEPGDA_02111 2.1e-125 yojG S deacetylase
PPHEPGDA_02112 2.2e-60 yojF S Protein of unknown function (DUF1806)
PPHEPGDA_02113 1.5e-43
PPHEPGDA_02114 5.6e-101 rarD S -transporter
PPHEPGDA_02115 1.1e-23 rarD S -transporter
PPHEPGDA_02116 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
PPHEPGDA_02117 2.6e-09
PPHEPGDA_02118 3.5e-127 gntP EG COG2610 H gluconate symporter and related permeases
PPHEPGDA_02119 7e-61 gntP EG COG2610 H gluconate symporter and related permeases
PPHEPGDA_02120 4.7e-64 yodA S tautomerase
PPHEPGDA_02121 4.4e-55 yodB K transcriptional
PPHEPGDA_02122 4.1e-107 yodC C nitroreductase
PPHEPGDA_02123 1.4e-45 L transposase activity
PPHEPGDA_02124 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_02125 2.1e-111 mhqD S Carboxylesterase
PPHEPGDA_02126 3.5e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
PPHEPGDA_02127 6.2e-28 S Protein of unknown function (DUF3311)
PPHEPGDA_02128 1.9e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PPHEPGDA_02129 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PPHEPGDA_02130 2.4e-127 yodH Q Methyltransferase
PPHEPGDA_02131 1.5e-23 yodI
PPHEPGDA_02132 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PPHEPGDA_02133 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PPHEPGDA_02134 5.3e-09
PPHEPGDA_02135 3.6e-54 yodL S YodL-like
PPHEPGDA_02136 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
PPHEPGDA_02137 2.8e-24 yozD S YozD-like protein
PPHEPGDA_02139 6e-123 yodN
PPHEPGDA_02140 1.4e-36 yozE S Belongs to the UPF0346 family
PPHEPGDA_02141 2.9e-47 yokU S YokU-like protein, putative antitoxin
PPHEPGDA_02142 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
PPHEPGDA_02143 3.3e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
PPHEPGDA_02144 1.3e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
PPHEPGDA_02145 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PPHEPGDA_02146 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PPHEPGDA_02147 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
PPHEPGDA_02149 4.1e-144 yiiD K acetyltransferase
PPHEPGDA_02150 2.2e-256 cgeD M maturation of the outermost layer of the spore
PPHEPGDA_02151 5.9e-38 cgeC
PPHEPGDA_02152 5.3e-63 cgeA
PPHEPGDA_02153 7.7e-177 cgeB S Spore maturation protein
PPHEPGDA_02154 1.9e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
PPHEPGDA_02155 8.1e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
PPHEPGDA_02156 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PPHEPGDA_02157 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PPHEPGDA_02158 1.6e-70 ypoP K transcriptional
PPHEPGDA_02159 4.9e-222 mepA V MATE efflux family protein
PPHEPGDA_02160 1.2e-28 ypmT S Uncharacterized ympT
PPHEPGDA_02161 9.4e-98 ypmS S protein conserved in bacteria
PPHEPGDA_02162 1.6e-137 ypmR E GDSL-like Lipase/Acylhydrolase
PPHEPGDA_02163 2.3e-105 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
PPHEPGDA_02164 3.1e-40 ypmP S Protein of unknown function (DUF2535)
PPHEPGDA_02165 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PPHEPGDA_02166 1.5e-183 pspF K Transcriptional regulator
PPHEPGDA_02167 2.7e-109 hlyIII S protein, Hemolysin III
PPHEPGDA_02168 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
PPHEPGDA_02169 8.2e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PPHEPGDA_02170 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PPHEPGDA_02171 5e-113 ypjP S YpjP-like protein
PPHEPGDA_02172 6.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
PPHEPGDA_02173 1.7e-75 yphP S Belongs to the UPF0403 family
PPHEPGDA_02174 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PPHEPGDA_02175 1.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
PPHEPGDA_02176 9e-110 ypgQ S phosphohydrolase
PPHEPGDA_02177 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PPHEPGDA_02178 8.9e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PPHEPGDA_02179 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
PPHEPGDA_02180 7.9e-31 cspD K Cold-shock protein
PPHEPGDA_02181 3.8e-16 degR
PPHEPGDA_02182 8.1e-31 S Protein of unknown function (DUF2564)
PPHEPGDA_02183 2.6e-27 ypeQ S Zinc-finger
PPHEPGDA_02184 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
PPHEPGDA_02185 6.6e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
PPHEPGDA_02186 1.8e-66 rnhA 3.1.26.4 L Ribonuclease
PPHEPGDA_02188 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
PPHEPGDA_02189 2e-07
PPHEPGDA_02190 2.9e-38 ypbS S Protein of unknown function (DUF2533)
PPHEPGDA_02191 0.0 ypbR S Dynamin family
PPHEPGDA_02192 1.1e-86 ypbQ S protein conserved in bacteria
PPHEPGDA_02193 6e-33 bcsA Q Naringenin-chalcone synthase
PPHEPGDA_02194 9.6e-158 bcsA Q Naringenin-chalcone synthase
PPHEPGDA_02195 1.5e-226 pbuX F xanthine
PPHEPGDA_02196 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PPHEPGDA_02197 2.3e-292 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
PPHEPGDA_02198 5.6e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
PPHEPGDA_02199 1.3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
PPHEPGDA_02200 1.1e-186 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
PPHEPGDA_02201 1.5e-186 ptxS K transcriptional
PPHEPGDA_02202 6.3e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PPHEPGDA_02203 4.8e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_02204 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
PPHEPGDA_02206 2.7e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PPHEPGDA_02207 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PPHEPGDA_02208 1.6e-89 ypsA S Belongs to the UPF0398 family
PPHEPGDA_02209 2.5e-236 yprB L RNase_H superfamily
PPHEPGDA_02210 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
PPHEPGDA_02211 1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
PPHEPGDA_02212 8e-70 hspX O Belongs to the small heat shock protein (HSP20) family
PPHEPGDA_02213 1.2e-48 yppG S YppG-like protein
PPHEPGDA_02215 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
PPHEPGDA_02218 5.4e-186 yppC S Protein of unknown function (DUF2515)
PPHEPGDA_02219 4.6e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PPHEPGDA_02220 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
PPHEPGDA_02221 4.7e-93 ypoC
PPHEPGDA_02222 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PPHEPGDA_02223 5.7e-129 dnaD L DNA replication protein DnaD
PPHEPGDA_02224 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
PPHEPGDA_02225 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PPHEPGDA_02226 2.2e-79 ypmB S protein conserved in bacteria
PPHEPGDA_02227 6.7e-23 ypmA S Protein of unknown function (DUF4264)
PPHEPGDA_02228 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PPHEPGDA_02229 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PPHEPGDA_02230 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PPHEPGDA_02231 2.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
PPHEPGDA_02232 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PPHEPGDA_02233 3.5e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PPHEPGDA_02234 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
PPHEPGDA_02235 1.7e-128 bshB1 S proteins, LmbE homologs
PPHEPGDA_02236 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
PPHEPGDA_02237 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PPHEPGDA_02238 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
PPHEPGDA_02239 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
PPHEPGDA_02240 1.1e-141 ypjB S sporulation protein
PPHEPGDA_02241 1.5e-98 ypjA S membrane
PPHEPGDA_02242 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
PPHEPGDA_02243 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
PPHEPGDA_02244 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
PPHEPGDA_02245 4.2e-77 ypiF S Protein of unknown function (DUF2487)
PPHEPGDA_02246 2.8e-99 ypiB S Belongs to the UPF0302 family
PPHEPGDA_02247 5.9e-233 S COG0457 FOG TPR repeat
PPHEPGDA_02248 7.6e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PPHEPGDA_02249 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PPHEPGDA_02250 3.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PPHEPGDA_02251 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PPHEPGDA_02252 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PPHEPGDA_02253 2e-115 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PPHEPGDA_02254 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PPHEPGDA_02255 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PPHEPGDA_02256 1.5e-294 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PPHEPGDA_02257 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
PPHEPGDA_02258 2.9e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PPHEPGDA_02259 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PPHEPGDA_02260 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
PPHEPGDA_02261 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PPHEPGDA_02262 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PPHEPGDA_02263 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
PPHEPGDA_02264 2.8e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
PPHEPGDA_02265 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
PPHEPGDA_02266 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
PPHEPGDA_02267 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PPHEPGDA_02268 6.4e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
PPHEPGDA_02269 2.3e-136 yphF
PPHEPGDA_02270 2e-18 yphE S Protein of unknown function (DUF2768)
PPHEPGDA_02271 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PPHEPGDA_02272 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PPHEPGDA_02273 7.9e-28 ypzH
PPHEPGDA_02274 2.5e-161 seaA S YIEGIA protein
PPHEPGDA_02275 6.7e-102 yphA
PPHEPGDA_02276 1e-07 S YpzI-like protein
PPHEPGDA_02277 2.7e-183 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PPHEPGDA_02278 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
PPHEPGDA_02279 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PPHEPGDA_02280 6.9e-23 S Family of unknown function (DUF5359)
PPHEPGDA_02281 2.3e-108 ypfA M Flagellar protein YcgR
PPHEPGDA_02282 1.4e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
PPHEPGDA_02283 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
PPHEPGDA_02284 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
PPHEPGDA_02285 3.1e-173 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
PPHEPGDA_02286 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPHEPGDA_02287 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
PPHEPGDA_02288 2.3e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
PPHEPGDA_02289 2.8e-81 ypbF S Protein of unknown function (DUF2663)
PPHEPGDA_02290 1.7e-78 ypbE M Lysin motif
PPHEPGDA_02291 1.1e-99 ypbD S metal-dependent membrane protease
PPHEPGDA_02292 8.6e-284 recQ 3.6.4.12 L DNA helicase
PPHEPGDA_02293 2.7e-199 ypbB 5.1.3.1 S protein conserved in bacteria
PPHEPGDA_02294 4.7e-41 fer C Ferredoxin
PPHEPGDA_02295 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PPHEPGDA_02296 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PPHEPGDA_02297 4.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PPHEPGDA_02298 3.1e-198 rsiX
PPHEPGDA_02299 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_02300 0.0 resE 2.7.13.3 T Histidine kinase
PPHEPGDA_02301 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_02302 1.7e-213 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
PPHEPGDA_02303 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
PPHEPGDA_02304 4.8e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
PPHEPGDA_02305 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPHEPGDA_02306 1.9e-87 spmB S Spore maturation protein
PPHEPGDA_02307 3.5e-103 spmA S Spore maturation protein
PPHEPGDA_02308 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
PPHEPGDA_02309 7.6e-97 ypuI S Protein of unknown function (DUF3907)
PPHEPGDA_02310 3.5e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PPHEPGDA_02311 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PPHEPGDA_02312 3e-90 ypuF S Domain of unknown function (DUF309)
PPHEPGDA_02313 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_02314 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
PPHEPGDA_02315 1.1e-228 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PPHEPGDA_02316 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
PPHEPGDA_02317 1.9e-203 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PPHEPGDA_02318 7.8e-55 ypuD
PPHEPGDA_02319 1.1e-93 sipT 3.4.21.89 U Belongs to the peptidase S26 family
PPHEPGDA_02320 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
PPHEPGDA_02322 3.6e-49 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPHEPGDA_02323 3.6e-31 S Pfam Transposase IS66
PPHEPGDA_02324 2.5e-26
PPHEPGDA_02325 6.8e-53 3.4.24.28 F DNA/RNA non-specific endonuclease
PPHEPGDA_02327 1.5e-70 O Papain family cysteine protease
PPHEPGDA_02328 5.5e-08
PPHEPGDA_02329 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_02330 1.8e-87 S Protein of unknown function (DUF3800)
PPHEPGDA_02334 4e-108 S aspartate phosphatase
PPHEPGDA_02335 9.5e-80 S SMI1-KNR4 cell-wall
PPHEPGDA_02337 1.1e-35 S Protein of unknown function (DUF1433)
PPHEPGDA_02338 1.2e-237 I Pfam Lipase (class 3)
PPHEPGDA_02339 6.7e-16
PPHEPGDA_02341 1.3e-18 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_02346 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PPHEPGDA_02347 3.6e-149 ypuA S Secreted protein
PPHEPGDA_02348 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PPHEPGDA_02349 1.7e-271 spoVAF EG Stage V sporulation protein AF
PPHEPGDA_02350 1.4e-110 spoVAEA S stage V sporulation protein
PPHEPGDA_02351 2.2e-57 spoVAEB S stage V sporulation protein
PPHEPGDA_02352 3.4e-191 spoVAD I Stage V sporulation protein AD
PPHEPGDA_02353 2.3e-78 spoVAC S stage V sporulation protein AC
PPHEPGDA_02354 1e-67 spoVAB S Stage V sporulation protein AB
PPHEPGDA_02355 9.6e-112 spoVAA S Stage V sporulation protein AA
PPHEPGDA_02356 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_02357 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
PPHEPGDA_02358 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
PPHEPGDA_02359 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
PPHEPGDA_02360 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PPHEPGDA_02361 2.6e-230 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PPHEPGDA_02362 2.4e-164 xerD L recombinase XerD
PPHEPGDA_02363 1.4e-36 S Protein of unknown function (DUF4227)
PPHEPGDA_02364 2.4e-80 fur P Belongs to the Fur family
PPHEPGDA_02365 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
PPHEPGDA_02366 3.2e-30 yqkK
PPHEPGDA_02367 5.5e-242 mleA 1.1.1.38 C malic enzyme
PPHEPGDA_02368 9.1e-235 mleN C Na H antiporter
PPHEPGDA_02369 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
PPHEPGDA_02370 1.8e-184 ansA 3.5.1.1 EJ L-asparaginase
PPHEPGDA_02371 1.3e-57 ansR K Transcriptional regulator
PPHEPGDA_02372 4.3e-222 yqxK 3.6.4.12 L DNA helicase
PPHEPGDA_02373 2.6e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
PPHEPGDA_02375 5.3e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
PPHEPGDA_02376 7e-12 yqkE S Protein of unknown function (DUF3886)
PPHEPGDA_02377 1.6e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
PPHEPGDA_02378 9.4e-39 yqkC S Protein of unknown function (DUF2552)
PPHEPGDA_02379 2.8e-54 yqkB S Belongs to the HesB IscA family
PPHEPGDA_02380 8.9e-195 yqkA K GrpB protein
PPHEPGDA_02381 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
PPHEPGDA_02382 8.1e-87 yqjY K acetyltransferase
PPHEPGDA_02383 1.7e-49 S YolD-like protein
PPHEPGDA_02384 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPHEPGDA_02386 1.3e-224 yqjV G Major Facilitator Superfamily
PPHEPGDA_02388 3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_02389 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PPHEPGDA_02390 7.1e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
PPHEPGDA_02391 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_02392 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
PPHEPGDA_02393 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPHEPGDA_02394 0.0 rocB E arginine degradation protein
PPHEPGDA_02395 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
PPHEPGDA_02396 1.4e-144 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PPHEPGDA_02397 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PPHEPGDA_02398 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PPHEPGDA_02399 2.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PPHEPGDA_02400 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PPHEPGDA_02401 8.4e-232 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PPHEPGDA_02402 6.2e-24 yqzJ
PPHEPGDA_02403 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPHEPGDA_02404 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
PPHEPGDA_02405 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
PPHEPGDA_02406 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
PPHEPGDA_02407 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
PPHEPGDA_02409 2.3e-98 yqjB S protein conserved in bacteria
PPHEPGDA_02410 3.3e-175 yqjA S Putative aromatic acid exporter C-terminal domain
PPHEPGDA_02411 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PPHEPGDA_02412 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
PPHEPGDA_02413 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
PPHEPGDA_02414 9.3e-77 yqiW S Belongs to the UPF0403 family
PPHEPGDA_02415 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PPHEPGDA_02416 7.5e-173 norA EGP Major facilitator Superfamily
PPHEPGDA_02417 2.6e-152 bmrR K helix_turn_helix, mercury resistance
PPHEPGDA_02418 2.6e-220 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PPHEPGDA_02419 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PPHEPGDA_02420 8e-185 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
PPHEPGDA_02421 1.3e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
PPHEPGDA_02422 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
PPHEPGDA_02423 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPHEPGDA_02424 3.9e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
PPHEPGDA_02425 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
PPHEPGDA_02426 4e-34 yqzF S Protein of unknown function (DUF2627)
PPHEPGDA_02427 3e-162 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
PPHEPGDA_02428 4.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
PPHEPGDA_02429 1.7e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
PPHEPGDA_02430 8.8e-212 mmgC I acyl-CoA dehydrogenase
PPHEPGDA_02431 2.3e-156 hbdA 1.1.1.157 I Dehydrogenase
PPHEPGDA_02432 5.9e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
PPHEPGDA_02433 8.9e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PPHEPGDA_02434 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
PPHEPGDA_02435 6e-27
PPHEPGDA_02436 4.7e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
PPHEPGDA_02438 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
PPHEPGDA_02439 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
PPHEPGDA_02440 5.5e-306 recN L May be involved in recombinational repair of damaged DNA
PPHEPGDA_02441 1.7e-78 argR K Regulates arginine biosynthesis genes
PPHEPGDA_02442 8.7e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
PPHEPGDA_02443 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PPHEPGDA_02444 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PPHEPGDA_02445 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPHEPGDA_02446 1.1e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PPHEPGDA_02447 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PPHEPGDA_02448 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PPHEPGDA_02449 6.2e-67 yqhY S protein conserved in bacteria
PPHEPGDA_02450 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PPHEPGDA_02451 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PPHEPGDA_02452 9.9e-91 spoIIIAH S SpoIIIAH-like protein
PPHEPGDA_02453 3.4e-102 spoIIIAG S stage III sporulation protein AG
PPHEPGDA_02454 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
PPHEPGDA_02455 4.9e-197 spoIIIAE S stage III sporulation protein AE
PPHEPGDA_02456 2.3e-58 spoIIIAD S Stage III sporulation protein AD
PPHEPGDA_02457 7.6e-29 spoIIIAC S stage III sporulation protein AC
PPHEPGDA_02458 4.1e-84 spoIIIAB S Stage III sporulation protein
PPHEPGDA_02459 1.2e-171 spoIIIAA S stage III sporulation protein AA
PPHEPGDA_02460 7.9e-37 yqhV S Protein of unknown function (DUF2619)
PPHEPGDA_02461 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PPHEPGDA_02462 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
PPHEPGDA_02463 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
PPHEPGDA_02464 2.3e-93 yqhR S Conserved membrane protein YqhR
PPHEPGDA_02465 2.3e-173 yqhQ S Protein of unknown function (DUF1385)
PPHEPGDA_02466 2.2e-61 yqhP
PPHEPGDA_02467 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
PPHEPGDA_02468 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
PPHEPGDA_02469 6.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
PPHEPGDA_02470 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
PPHEPGDA_02471 2e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PPHEPGDA_02472 3.2e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PPHEPGDA_02473 4e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
PPHEPGDA_02474 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PPHEPGDA_02475 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
PPHEPGDA_02476 1.2e-24 sinI S Anti-repressor SinI
PPHEPGDA_02477 1e-54 sinR K transcriptional
PPHEPGDA_02478 5.6e-141 tasA S Cell division protein FtsN
PPHEPGDA_02479 6.9e-64 sipW 3.4.21.89 U Signal peptidase
PPHEPGDA_02480 1.1e-112 yqxM
PPHEPGDA_02481 7.3e-54 yqzG S Protein of unknown function (DUF3889)
PPHEPGDA_02482 4.4e-25 yqzE S YqzE-like protein
PPHEPGDA_02483 8.8e-44 S ComG operon protein 7
PPHEPGDA_02484 2.2e-34 comGF U Putative Competence protein ComGF
PPHEPGDA_02485 1.5e-58 comGE
PPHEPGDA_02486 3.5e-68 gspH NU protein transport across the cell outer membrane
PPHEPGDA_02487 1.4e-47 comGC U Required for transformation and DNA binding
PPHEPGDA_02488 7.8e-175 comGB NU COG1459 Type II secretory pathway, component PulF
PPHEPGDA_02489 7.3e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PPHEPGDA_02491 4.7e-174 corA P Mg2 transporter protein
PPHEPGDA_02492 4.9e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PPHEPGDA_02493 6e-149 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
PPHEPGDA_02495 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
PPHEPGDA_02496 1.8e-37 yqgY S Protein of unknown function (DUF2626)
PPHEPGDA_02497 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PPHEPGDA_02498 8.9e-23 yqgW S Protein of unknown function (DUF2759)
PPHEPGDA_02499 6.9e-50 yqgV S Thiamine-binding protein
PPHEPGDA_02500 5.1e-198 yqgU
PPHEPGDA_02501 2.1e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
PPHEPGDA_02502 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPHEPGDA_02503 1.5e-180 glcK 2.7.1.2 G Glucokinase
PPHEPGDA_02504 4.3e-33 yqgQ S Protein conserved in bacteria
PPHEPGDA_02505 3.4e-259 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PPHEPGDA_02506 2.5e-09 yqgO
PPHEPGDA_02507 5.1e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PPHEPGDA_02508 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PPHEPGDA_02509 1.2e-194 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
PPHEPGDA_02511 3.5e-50 yqzD
PPHEPGDA_02512 7.3e-72 yqzC S YceG-like family
PPHEPGDA_02513 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPHEPGDA_02514 5.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PPHEPGDA_02515 4.4e-158 pstA P Phosphate transport system permease
PPHEPGDA_02516 3.2e-159 pstC P probably responsible for the translocation of the substrate across the membrane
PPHEPGDA_02517 2.6e-150 pstS P Phosphate
PPHEPGDA_02518 0.0 pbpA 3.4.16.4 M penicillin-binding protein
PPHEPGDA_02519 2.5e-231 yqgE EGP Major facilitator superfamily
PPHEPGDA_02520 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
PPHEPGDA_02521 2.6e-72 yqgC S protein conserved in bacteria
PPHEPGDA_02522 8.7e-131 yqgB S Protein of unknown function (DUF1189)
PPHEPGDA_02523 5.8e-46 yqfZ M LysM domain
PPHEPGDA_02524 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PPHEPGDA_02525 4.3e-62 yqfX S membrane
PPHEPGDA_02526 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
PPHEPGDA_02527 1.9e-77 zur P Belongs to the Fur family
PPHEPGDA_02528 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
PPHEPGDA_02529 2.1e-36 yqfT S Protein of unknown function (DUF2624)
PPHEPGDA_02530 2.2e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PPHEPGDA_02531 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PPHEPGDA_02532 2.9e-14 yqfQ S YqfQ-like protein
PPHEPGDA_02533 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PPHEPGDA_02534 1.9e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PPHEPGDA_02535 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
PPHEPGDA_02536 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
PPHEPGDA_02537 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PPHEPGDA_02538 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PPHEPGDA_02539 1.3e-87 yaiI S Belongs to the UPF0178 family
PPHEPGDA_02540 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PPHEPGDA_02541 4.5e-112 ccpN K CBS domain
PPHEPGDA_02542 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PPHEPGDA_02543 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PPHEPGDA_02544 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
PPHEPGDA_02545 8.4e-19 S YqzL-like protein
PPHEPGDA_02546 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PPHEPGDA_02547 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PPHEPGDA_02548 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PPHEPGDA_02549 2e-80 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PPHEPGDA_02550 0.0 yqfF S membrane-associated HD superfamily hydrolase
PPHEPGDA_02552 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
PPHEPGDA_02553 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
PPHEPGDA_02554 2.7e-45 yqfC S sporulation protein YqfC
PPHEPGDA_02555 1.3e-19 yqfB
PPHEPGDA_02556 4.3e-122 yqfA S UPF0365 protein
PPHEPGDA_02557 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
PPHEPGDA_02558 7e-64 yqeY S Yqey-like protein
PPHEPGDA_02559 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PPHEPGDA_02560 4.1e-157 yqeW P COG1283 Na phosphate symporter
PPHEPGDA_02561 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
PPHEPGDA_02562 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PPHEPGDA_02563 9.2e-175 prmA J Methylates ribosomal protein L11
PPHEPGDA_02564 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PPHEPGDA_02565 0.0 dnaK O Heat shock 70 kDa protein
PPHEPGDA_02566 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PPHEPGDA_02567 6.8e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PPHEPGDA_02568 4.5e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
PPHEPGDA_02569 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PPHEPGDA_02570 7.2e-53 yqxA S Protein of unknown function (DUF3679)
PPHEPGDA_02571 1.5e-222 spoIIP M stage II sporulation protein P
PPHEPGDA_02572 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
PPHEPGDA_02573 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
PPHEPGDA_02574 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
PPHEPGDA_02575 4.1e-15 S YqzM-like protein
PPHEPGDA_02576 0.0 comEC S Competence protein ComEC
PPHEPGDA_02577 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
PPHEPGDA_02578 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
PPHEPGDA_02579 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PPHEPGDA_02580 1.8e-136 yqeM Q Methyltransferase
PPHEPGDA_02581 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PPHEPGDA_02582 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PPHEPGDA_02583 3.8e-107 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PPHEPGDA_02584 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
PPHEPGDA_02585 3.9e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PPHEPGDA_02586 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PPHEPGDA_02587 5.3e-95 yqeG S hydrolase of the HAD superfamily
PPHEPGDA_02589 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
PPHEPGDA_02590 1.5e-135 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_02591 8.8e-105 yqeD S SNARE associated Golgi protein
PPHEPGDA_02592 1.5e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
PPHEPGDA_02593 2.8e-131 yqeB
PPHEPGDA_02594 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
PPHEPGDA_02595 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PPHEPGDA_02596 1.1e-256 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PPHEPGDA_02597 5e-154 K Transcriptional regulator
PPHEPGDA_02598 1e-66 K Glyoxalase bleomycin resistance protein dioxygenase
PPHEPGDA_02600 2.6e-208 S Aspartate phosphatase response regulator
PPHEPGDA_02601 3e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PPHEPGDA_02602 1.5e-178 L nucleic acid phosphodiester bond hydrolysis
PPHEPGDA_02603 4.8e-32 L nucleic acid phosphodiester bond hydrolysis
PPHEPGDA_02605 1.9e-29 S SMI1 / KNR4 family
PPHEPGDA_02606 4e-22 S SMI1-KNR4 cell-wall
PPHEPGDA_02607 5.3e-46
PPHEPGDA_02612 6.6e-28 S Suppressor of fused protein (SUFU)
PPHEPGDA_02613 3.3e-30
PPHEPGDA_02615 1.5e-21 xkdM S Phage tail tube protein
PPHEPGDA_02616 2.1e-10
PPHEPGDA_02617 9.9e-119 L PhoH-like protein
PPHEPGDA_02618 1.1e-220 L Transposase
PPHEPGDA_02624 3.1e-150 bltR K helix_turn_helix, mercury resistance
PPHEPGDA_02625 3.9e-210 blt EGP Major facilitator Superfamily
PPHEPGDA_02626 5.9e-82 bltD 2.3.1.57 K FR47-like protein
PPHEPGDA_02627 1.2e-238 L COG3328 Transposase and inactivated derivatives
PPHEPGDA_02628 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
PPHEPGDA_02629 3.9e-16 S YrzO-like protein
PPHEPGDA_02630 7.3e-167 yrdR EG EamA-like transporter family
PPHEPGDA_02631 3.9e-159 yrdQ K Transcriptional regulator
PPHEPGDA_02632 8.6e-198 trkA P Oxidoreductase
PPHEPGDA_02633 1.5e-153 czcD P COG1230 Co Zn Cd efflux system component
PPHEPGDA_02634 3e-17 yodA S tautomerase
PPHEPGDA_02635 2.3e-224 brnQ E Component of the transport system for branched-chain amino acids
PPHEPGDA_02636 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
PPHEPGDA_02637 6.2e-137 azlC E AzlC protein
PPHEPGDA_02638 5.3e-78 bkdR K helix_turn_helix ASNC type
PPHEPGDA_02639 1.1e-40 yrdF K ribonuclease inhibitor
PPHEPGDA_02640 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
PPHEPGDA_02641 3.3e-57 S Protein of unknown function (DUF2568)
PPHEPGDA_02642 1.4e-89 yrdA S DinB family
PPHEPGDA_02643 1.2e-165 aadK G Streptomycin adenylyltransferase
PPHEPGDA_02644 1.2e-191 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
PPHEPGDA_02645 9.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PPHEPGDA_02646 8.7e-125 yrpD S Domain of unknown function, YrpD
PPHEPGDA_02648 2.9e-110 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
PPHEPGDA_02649 1e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_02650 3.6e-134 yrpG C Aldo/keto reductase family
PPHEPGDA_02651 3.6e-44 yrpG C Aldo/keto reductase family
PPHEPGDA_02652 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
PPHEPGDA_02653 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_02654 1.3e-148 S Alpha beta hydrolase
PPHEPGDA_02655 1.7e-60 T sh3 domain protein
PPHEPGDA_02656 2.4e-61 T sh3 domain protein
PPHEPGDA_02657 1.3e-66 E Glyoxalase-like domain
PPHEPGDA_02658 5.3e-37 yraG
PPHEPGDA_02659 6.4e-63 yraF M Spore coat protein
PPHEPGDA_02660 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PPHEPGDA_02661 1.8e-24 yraE
PPHEPGDA_02662 1.1e-49 yraD M Spore coat protein
PPHEPGDA_02663 1.3e-46 yraB K helix_turn_helix, mercury resistance
PPHEPGDA_02664 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
PPHEPGDA_02665 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
PPHEPGDA_02666 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
PPHEPGDA_02667 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
PPHEPGDA_02668 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
PPHEPGDA_02669 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
PPHEPGDA_02670 6.9e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
PPHEPGDA_02671 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
PPHEPGDA_02672 0.0 levR K PTS system fructose IIA component
PPHEPGDA_02673 3.7e-249 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_02674 1.1e-105 yrhP E LysE type translocator
PPHEPGDA_02675 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
PPHEPGDA_02676 3.1e-37 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_02677 3.1e-37 sigV K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_02678 6.1e-149 rsiV S Protein of unknown function (DUF3298)
PPHEPGDA_02679 0.0 yrhL I Acyltransferase family
PPHEPGDA_02680 1.2e-43 yrhK S YrhK-like protein
PPHEPGDA_02681 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
PPHEPGDA_02682 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
PPHEPGDA_02683 2.8e-91 yrhH Q methyltransferase
PPHEPGDA_02686 1.2e-141 focA P Formate nitrite
PPHEPGDA_02687 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
PPHEPGDA_02688 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
PPHEPGDA_02689 2.4e-78 yrhD S Protein of unknown function (DUF1641)
PPHEPGDA_02690 1.8e-34 yrhC S YrhC-like protein
PPHEPGDA_02691 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
PPHEPGDA_02692 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
PPHEPGDA_02693 3.6e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PPHEPGDA_02694 8.4e-119 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
PPHEPGDA_02695 1e-25 yrzA S Protein of unknown function (DUF2536)
PPHEPGDA_02696 5.5e-63 yrrS S Protein of unknown function (DUF1510)
PPHEPGDA_02697 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
PPHEPGDA_02698 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PPHEPGDA_02699 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
PPHEPGDA_02700 2.7e-246 yegQ O COG0826 Collagenase and related proteases
PPHEPGDA_02701 4.3e-172 yegQ O Peptidase U32
PPHEPGDA_02702 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
PPHEPGDA_02703 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PPHEPGDA_02704 1.2e-45 yrzB S Belongs to the UPF0473 family
PPHEPGDA_02705 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PPHEPGDA_02706 1.7e-41 yrzL S Belongs to the UPF0297 family
PPHEPGDA_02707 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PPHEPGDA_02708 7.8e-170 yrrI S AI-2E family transporter
PPHEPGDA_02709 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
PPHEPGDA_02710 4.8e-143 glnH ET Belongs to the bacterial solute-binding protein 3 family
PPHEPGDA_02711 8.8e-108 gluC P ABC transporter
PPHEPGDA_02712 7.6e-107 glnP P ABC transporter
PPHEPGDA_02714 3.7e-30 yrzR
PPHEPGDA_02715 3.9e-81 yrrD S protein conserved in bacteria
PPHEPGDA_02716 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PPHEPGDA_02717 1.4e-15 S COG0457 FOG TPR repeat
PPHEPGDA_02718 2.5e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PPHEPGDA_02719 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
PPHEPGDA_02720 1.2e-70 cymR K Transcriptional regulator
PPHEPGDA_02721 1.1e-234 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
PPHEPGDA_02722 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
PPHEPGDA_02723 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PPHEPGDA_02724 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
PPHEPGDA_02726 7.4e-262 lytH 3.5.1.28 M COG3103 SH3 domain protein
PPHEPGDA_02727 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PPHEPGDA_02728 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PPHEPGDA_02729 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PPHEPGDA_02730 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PPHEPGDA_02731 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
PPHEPGDA_02732 4.3e-86 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
PPHEPGDA_02733 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PPHEPGDA_02734 9.4e-49 yrzD S Post-transcriptional regulator
PPHEPGDA_02735 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_02736 1.6e-112 yrbG S membrane
PPHEPGDA_02737 4.4e-74 yrzE S Protein of unknown function (DUF3792)
PPHEPGDA_02738 1.1e-38 yajC U Preprotein translocase subunit YajC
PPHEPGDA_02739 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PPHEPGDA_02740 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PPHEPGDA_02741 2.6e-18 yrzS S Protein of unknown function (DUF2905)
PPHEPGDA_02742 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PPHEPGDA_02743 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PPHEPGDA_02744 1.1e-92 bofC S BofC C-terminal domain
PPHEPGDA_02745 7.6e-252 csbX EGP Major facilitator Superfamily
PPHEPGDA_02746 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
PPHEPGDA_02747 5.5e-118 yrzF T serine threonine protein kinase
PPHEPGDA_02749 5.2e-51 S Family of unknown function (DUF5412)
PPHEPGDA_02750 1.2e-261 alsT E Sodium alanine symporter
PPHEPGDA_02751 5.5e-127 yebC K transcriptional regulatory protein
PPHEPGDA_02752 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PPHEPGDA_02753 3.1e-156 safA M spore coat assembly protein SafA
PPHEPGDA_02754 1.6e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
PPHEPGDA_02755 3.4e-155 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
PPHEPGDA_02756 3.7e-301 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
PPHEPGDA_02757 1.3e-226 nifS 2.8.1.7 E Cysteine desulfurase
PPHEPGDA_02758 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
PPHEPGDA_02759 6.3e-162 pheA 4.2.1.51 E Prephenate dehydratase
PPHEPGDA_02760 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
PPHEPGDA_02761 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PPHEPGDA_02762 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
PPHEPGDA_02763 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PPHEPGDA_02764 4.1e-56 ysxB J ribosomal protein
PPHEPGDA_02765 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PPHEPGDA_02766 2e-160 spoIVFB S Stage IV sporulation protein
PPHEPGDA_02767 1.4e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
PPHEPGDA_02768 3.3e-144 minD D Belongs to the ParA family
PPHEPGDA_02769 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PPHEPGDA_02770 1.4e-84 mreD M shape-determining protein
PPHEPGDA_02771 1.1e-156 mreC M Involved in formation and maintenance of cell shape
PPHEPGDA_02772 1.8e-184 mreB D Rod shape-determining protein MreB
PPHEPGDA_02773 1.3e-125 radC E Belongs to the UPF0758 family
PPHEPGDA_02774 2.4e-101 maf D septum formation protein Maf
PPHEPGDA_02775 6e-164 spoIIB S Sporulation related domain
PPHEPGDA_02776 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
PPHEPGDA_02777 2.8e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PPHEPGDA_02778 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PPHEPGDA_02779 1.6e-25
PPHEPGDA_02780 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
PPHEPGDA_02781 3.1e-192 spoVID M stage VI sporulation protein D
PPHEPGDA_02782 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
PPHEPGDA_02783 8.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
PPHEPGDA_02784 7.9e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
PPHEPGDA_02785 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
PPHEPGDA_02786 3.6e-146 hemX O cytochrome C
PPHEPGDA_02787 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PPHEPGDA_02788 5.4e-89 ysxD
PPHEPGDA_02789 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
PPHEPGDA_02790 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PPHEPGDA_02791 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
PPHEPGDA_02792 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PPHEPGDA_02793 1.8e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PPHEPGDA_02794 1.9e-186 ysoA H Tetratricopeptide repeat
PPHEPGDA_02795 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPHEPGDA_02796 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PPHEPGDA_02797 5.3e-198 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PPHEPGDA_02798 3.3e-286 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PPHEPGDA_02799 4.5e-191 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PPHEPGDA_02800 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
PPHEPGDA_02801 0.0 ilvB 2.2.1.6 E Acetolactate synthase
PPHEPGDA_02803 3.6e-64 ysnE K acetyltransferase
PPHEPGDA_02804 5.5e-131 ysnF S protein conserved in bacteria
PPHEPGDA_02805 1.9e-66 pinR3 L Resolvase, N terminal domain
PPHEPGDA_02806 2.3e-78 hsdS 3.1.21.3 L Type I restriction modification DNA specificity domain
PPHEPGDA_02807 1e-249 hsdM 2.1.1.72 L type I restriction-modification system
PPHEPGDA_02808 0.0 hsdR 3.1.21.3 L COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases
PPHEPGDA_02809 1.4e-41
PPHEPGDA_02811 1.6e-132 L Phage integrase family
PPHEPGDA_02813 1.4e-92 ysnB S Phosphoesterase
PPHEPGDA_02814 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PPHEPGDA_02815 1.2e-132 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PPHEPGDA_02816 2.9e-196 gerM S COG5401 Spore germination protein
PPHEPGDA_02817 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PPHEPGDA_02818 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_02819 3.3e-30 gerE K Transcriptional regulator
PPHEPGDA_02820 5.5e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
PPHEPGDA_02821 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PPHEPGDA_02822 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
PPHEPGDA_02823 2.4e-107 sdhC C succinate dehydrogenase
PPHEPGDA_02824 1.2e-79 yslB S Protein of unknown function (DUF2507)
PPHEPGDA_02825 1.8e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
PPHEPGDA_02826 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PPHEPGDA_02827 2e-52 trxA O Belongs to the thioredoxin family
PPHEPGDA_02828 1.7e-303 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
PPHEPGDA_02830 2.1e-177 etfA C Electron transfer flavoprotein
PPHEPGDA_02831 4.5e-135 etfB C Electron transfer flavoprotein
PPHEPGDA_02832 4.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
PPHEPGDA_02833 4e-99 fadR K Transcriptional regulator
PPHEPGDA_02834 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
PPHEPGDA_02835 7.3e-68 yshE S membrane
PPHEPGDA_02836 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PPHEPGDA_02837 0.0 polX L COG1796 DNA polymerase IV (family X)
PPHEPGDA_02838 1.3e-85 cvpA S membrane protein, required for colicin V production
PPHEPGDA_02839 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PPHEPGDA_02840 7.1e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PPHEPGDA_02841 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPHEPGDA_02842 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PPHEPGDA_02843 1.7e-131 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PPHEPGDA_02844 2.6e-32 sspI S Belongs to the SspI family
PPHEPGDA_02845 5.9e-205 ysfB KT regulator
PPHEPGDA_02846 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
PPHEPGDA_02847 2.6e-255 glcF C Glycolate oxidase
PPHEPGDA_02848 1e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
PPHEPGDA_02849 0.0 cstA T Carbon starvation protein
PPHEPGDA_02850 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
PPHEPGDA_02851 1.7e-143 araQ G transport system permease
PPHEPGDA_02852 4.2e-167 araP G carbohydrate transport
PPHEPGDA_02853 1.7e-251 araN G carbohydrate transport
PPHEPGDA_02854 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
PPHEPGDA_02855 6.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PPHEPGDA_02856 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
PPHEPGDA_02857 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
PPHEPGDA_02858 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PPHEPGDA_02859 1.2e-99 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_02860 7.9e-57 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_02861 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
PPHEPGDA_02862 9.2e-68 ysdB S Sigma-w pathway protein YsdB
PPHEPGDA_02863 1.7e-44 ysdA S Membrane
PPHEPGDA_02864 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PPHEPGDA_02865 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PPHEPGDA_02866 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PPHEPGDA_02868 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PPHEPGDA_02869 1.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PPHEPGDA_02870 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
PPHEPGDA_02871 0.0 lytS 2.7.13.3 T Histidine kinase
PPHEPGDA_02872 7.3e-149 ysaA S HAD-hyrolase-like
PPHEPGDA_02873 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PPHEPGDA_02875 9.3e-158 ytxC S YtxC-like family
PPHEPGDA_02876 4.9e-111 ytxB S SNARE associated Golgi protein
PPHEPGDA_02877 3e-173 dnaI L Primosomal protein DnaI
PPHEPGDA_02878 3.5e-266 dnaB L Membrane attachment protein
PPHEPGDA_02879 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PPHEPGDA_02880 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
PPHEPGDA_02881 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PPHEPGDA_02882 9.9e-67 ytcD K Transcriptional regulator
PPHEPGDA_02883 4.9e-205 ytbD EGP Major facilitator Superfamily
PPHEPGDA_02884 8.9e-161 ytbE S reductase
PPHEPGDA_02885 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PPHEPGDA_02886 1.1e-107 ytaF P Probably functions as a manganese efflux pump
PPHEPGDA_02887 3.8e-156 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PPHEPGDA_02888 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PPHEPGDA_02889 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
PPHEPGDA_02890 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_02891 1.2e-169 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
PPHEPGDA_02892 4.1e-242 icd 1.1.1.42 C isocitrate
PPHEPGDA_02893 1.1e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
PPHEPGDA_02894 4.7e-71 yeaL S membrane
PPHEPGDA_02895 9.9e-192 ytvI S sporulation integral membrane protein YtvI
PPHEPGDA_02896 2.3e-62 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
PPHEPGDA_02897 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PPHEPGDA_02898 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PPHEPGDA_02899 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PPHEPGDA_02900 9.2e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PPHEPGDA_02901 2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
PPHEPGDA_02902 0.0 dnaE 2.7.7.7 L DNA polymerase
PPHEPGDA_02903 3.2e-56 ytrH S Sporulation protein YtrH
PPHEPGDA_02904 8.2e-69 ytrI
PPHEPGDA_02905 9.2e-29
PPHEPGDA_02906 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
PPHEPGDA_02907 2.4e-47 ytpI S YtpI-like protein
PPHEPGDA_02908 8e-241 ytoI K transcriptional regulator containing CBS domains
PPHEPGDA_02909 1.7e-130 ytkL S Belongs to the UPF0173 family
PPHEPGDA_02910 3.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_02912 6.4e-265 argH 4.3.2.1 E argininosuccinate lyase
PPHEPGDA_02913 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PPHEPGDA_02914 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
PPHEPGDA_02915 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PPHEPGDA_02916 7.3e-162 ytxK 2.1.1.72 L DNA methylase
PPHEPGDA_02917 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PPHEPGDA_02918 8.7e-70 ytfJ S Sporulation protein YtfJ
PPHEPGDA_02919 5.6e-116 ytfI S Protein of unknown function (DUF2953)
PPHEPGDA_02920 2.5e-86 yteJ S RDD family
PPHEPGDA_02921 1.3e-177 sppA OU signal peptide peptidase SppA
PPHEPGDA_02922 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PPHEPGDA_02923 0.0 ytcJ S amidohydrolase
PPHEPGDA_02924 5.5e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PPHEPGDA_02925 1e-28 sspB S spore protein
PPHEPGDA_02926 1e-226 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PPHEPGDA_02927 2.7e-208 iscS2 2.8.1.7 E Cysteine desulfurase
PPHEPGDA_02928 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
PPHEPGDA_02929 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PPHEPGDA_02930 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
PPHEPGDA_02931 1e-108 yttP K Transcriptional regulator
PPHEPGDA_02932 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
PPHEPGDA_02933 2.4e-309 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
PPHEPGDA_02934 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PPHEPGDA_02936 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPHEPGDA_02937 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
PPHEPGDA_02938 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
PPHEPGDA_02939 1.3e-116 acuB S Domain in cystathionine beta-synthase and other proteins.
PPHEPGDA_02940 8e-224 acuC BQ histone deacetylase
PPHEPGDA_02941 5.2e-125 motS N Flagellar motor protein
PPHEPGDA_02942 2.1e-146 motA N flagellar motor
PPHEPGDA_02943 1.7e-182 ccpA K catabolite control protein A
PPHEPGDA_02944 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
PPHEPGDA_02945 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
PPHEPGDA_02946 6.6e-17 ytxH S COG4980 Gas vesicle protein
PPHEPGDA_02947 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PPHEPGDA_02948 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PPHEPGDA_02949 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PPHEPGDA_02950 2.8e-108 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PPHEPGDA_02951 4.8e-148 ytpQ S Belongs to the UPF0354 family
PPHEPGDA_02952 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PPHEPGDA_02953 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
PPHEPGDA_02954 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PPHEPGDA_02955 1.1e-50 ytzB S small secreted protein
PPHEPGDA_02956 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
PPHEPGDA_02957 4.2e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
PPHEPGDA_02958 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PPHEPGDA_02959 2e-45 ytzH S YtzH-like protein
PPHEPGDA_02960 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
PPHEPGDA_02961 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PPHEPGDA_02962 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PPHEPGDA_02963 2.2e-165 ytlQ
PPHEPGDA_02964 3e-101 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
PPHEPGDA_02965 1.5e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PPHEPGDA_02966 3.9e-270 pepV 3.5.1.18 E Dipeptidase
PPHEPGDA_02967 2.1e-225 pbuO S permease
PPHEPGDA_02968 1.1e-201 ythQ U Bacterial ABC transporter protein EcsB
PPHEPGDA_02969 1.4e-130 ythP V ABC transporter
PPHEPGDA_02970 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
PPHEPGDA_02971 2.2e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PPHEPGDA_02972 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_02973 1.4e-231 ytfP S HI0933-like protein
PPHEPGDA_02974 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PPHEPGDA_02975 3.1e-26 yteV S Sporulation protein Cse60
PPHEPGDA_02976 4.5e-75 yteU S Integral membrane protein
PPHEPGDA_02977 8.5e-198 yteT S Oxidoreductase family, C-terminal alpha/beta domain
PPHEPGDA_02978 5.6e-71 yteS G transport
PPHEPGDA_02979 6.6e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
PPHEPGDA_02980 1.7e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
PPHEPGDA_02981 9.5e-278 ytdP K Transcriptional regulator
PPHEPGDA_02982 9.6e-118 ytdP K Transcriptional regulator
PPHEPGDA_02983 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
PPHEPGDA_02984 8.2e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
PPHEPGDA_02985 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
PPHEPGDA_02986 1e-218 bioI 1.14.14.46 C Cytochrome P450
PPHEPGDA_02987 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PPHEPGDA_02988 1.3e-54 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PPHEPGDA_02989 5.3e-45 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PPHEPGDA_02990 6.4e-199 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PPHEPGDA_02991 2.5e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
PPHEPGDA_02992 1.8e-118 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
PPHEPGDA_02993 1.9e-172 ytaP S Acetyl xylan esterase (AXE1)
PPHEPGDA_02994 1.8e-187 msmR K Transcriptional regulator
PPHEPGDA_02995 4e-245 msmE G Bacterial extracellular solute-binding protein
PPHEPGDA_02996 6.2e-168 amyD P ABC transporter
PPHEPGDA_02997 2.8e-143 amyC P ABC transporter (permease)
PPHEPGDA_02998 1.2e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
PPHEPGDA_02999 2.1e-51 ytwF P Sulfurtransferase
PPHEPGDA_03000 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PPHEPGDA_03001 7.7e-55 ytvB S Protein of unknown function (DUF4257)
PPHEPGDA_03002 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
PPHEPGDA_03003 3.3e-209 yttB EGP Major facilitator Superfamily
PPHEPGDA_03004 3.9e-43 yttA 2.7.13.3 S Pfam Transposase IS66
PPHEPGDA_03005 0.0 bceB V ABC transporter (permease)
PPHEPGDA_03006 1.1e-138 bceA V ABC transporter, ATP-binding protein
PPHEPGDA_03007 1.6e-185 T PhoQ Sensor
PPHEPGDA_03008 2.6e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_03009 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
PPHEPGDA_03010 9.1e-127 ytrE V ABC transporter, ATP-binding protein
PPHEPGDA_03011 1.3e-147
PPHEPGDA_03012 4.7e-161 P ABC-2 family transporter protein
PPHEPGDA_03013 4.2e-161 ytrB P abc transporter atp-binding protein
PPHEPGDA_03014 5.1e-66 ytrA K GntR family transcriptional regulator
PPHEPGDA_03016 6.7e-41 ytzC S Protein of unknown function (DUF2524)
PPHEPGDA_03017 4e-189 yhcC S Fe-S oxidoreductase
PPHEPGDA_03018 3.3e-106 ytqB J Putative rRNA methylase
PPHEPGDA_03019 1.1e-214 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
PPHEPGDA_03020 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
PPHEPGDA_03021 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
PPHEPGDA_03022 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_03023 0.0 asnB 6.3.5.4 E Asparagine synthase
PPHEPGDA_03024 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PPHEPGDA_03025 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PPHEPGDA_03026 1.6e-38 ytmB S Protein of unknown function (DUF2584)
PPHEPGDA_03027 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
PPHEPGDA_03028 1.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
PPHEPGDA_03029 1.4e-144 ytlC P ABC transporter
PPHEPGDA_03030 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
PPHEPGDA_03031 6.3e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
PPHEPGDA_03032 5.4e-63 ytkC S Bacteriophage holin family
PPHEPGDA_03033 2.1e-76 dps P Belongs to the Dps family
PPHEPGDA_03035 1.1e-72 ytkA S YtkA-like
PPHEPGDA_03036 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PPHEPGDA_03037 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PPHEPGDA_03038 6.1e-41 rpmE2 J Ribosomal protein L31
PPHEPGDA_03039 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
PPHEPGDA_03040 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
PPHEPGDA_03041 4.3e-24 S Domain of Unknown Function (DUF1540)
PPHEPGDA_03042 6.8e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
PPHEPGDA_03043 5.7e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
PPHEPGDA_03044 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
PPHEPGDA_03045 6.7e-170 troA P Belongs to the bacterial solute-binding protein 9 family
PPHEPGDA_03046 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PPHEPGDA_03047 2.2e-276 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
PPHEPGDA_03048 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
PPHEPGDA_03049 1.6e-154 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
PPHEPGDA_03050 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PPHEPGDA_03051 2.5e-272 menF 5.4.4.2 HQ Isochorismate synthase
PPHEPGDA_03052 7.4e-132 dksA T COG1734 DnaK suppressor protein
PPHEPGDA_03053 5.6e-152 galU 2.7.7.9 M Nucleotidyl transferase
PPHEPGDA_03054 1.3e-243 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PPHEPGDA_03055 2.2e-176 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
PPHEPGDA_03056 8.4e-229 ytcC M Glycosyltransferase Family 4
PPHEPGDA_03058 3.7e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
PPHEPGDA_03059 1.1e-214 cotSA M Glycosyl transferases group 1
PPHEPGDA_03060 2.2e-204 cotI S Spore coat protein
PPHEPGDA_03061 6.6e-73 tspO T membrane
PPHEPGDA_03062 2.7e-182 L COG3666 Transposase and inactivated derivatives
PPHEPGDA_03063 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PPHEPGDA_03064 2.5e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PPHEPGDA_03065 3.7e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
PPHEPGDA_03066 5.2e-196 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PPHEPGDA_03067 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PPHEPGDA_03076 7.8e-08
PPHEPGDA_03077 1.3e-09
PPHEPGDA_03084 2e-08
PPHEPGDA_03089 3.4e-39 S COG NOG14552 non supervised orthologous group
PPHEPGDA_03090 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
PPHEPGDA_03091 2.9e-93 M1-753 M FR47-like protein
PPHEPGDA_03092 3.5e-187 yuaG 3.4.21.72 S protein conserved in bacteria
PPHEPGDA_03093 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
PPHEPGDA_03094 5.3e-09 yuaE S DinB superfamily
PPHEPGDA_03095 8e-23 yuaE S DinB superfamily
PPHEPGDA_03096 8.1e-105 yuaD
PPHEPGDA_03097 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
PPHEPGDA_03098 4e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
PPHEPGDA_03099 5.5e-95 yuaC K Belongs to the GbsR family
PPHEPGDA_03100 2.2e-91 yuaB
PPHEPGDA_03101 1.2e-120 ktrA P COG0569 K transport systems, NAD-binding component
PPHEPGDA_03102 1.6e-236 ktrB P Potassium
PPHEPGDA_03103 1e-38 yiaA S yiaA/B two helix domain
PPHEPGDA_03104 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PPHEPGDA_03105 1.7e-274 yubD P Major Facilitator Superfamily
PPHEPGDA_03106 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
PPHEPGDA_03108 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PPHEPGDA_03109 1.3e-194 yubA S transporter activity
PPHEPGDA_03110 3.3e-183 ygjR S Oxidoreductase
PPHEPGDA_03111 7.8e-202 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
PPHEPGDA_03112 1.4e-22 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
PPHEPGDA_03113 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
PPHEPGDA_03114 4.3e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PPHEPGDA_03115 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
PPHEPGDA_03116 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
PPHEPGDA_03117 7.3e-238 mcpA NT chemotaxis protein
PPHEPGDA_03118 9.4e-278 mcpA NT chemotaxis protein
PPHEPGDA_03119 2.4e-135 mcpA NT chemotaxis protein
PPHEPGDA_03120 2.2e-52 mcpA NT chemotaxis protein
PPHEPGDA_03121 7.1e-225 mcpA NT chemotaxis protein
PPHEPGDA_03122 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
PPHEPGDA_03123 1.8e-35
PPHEPGDA_03124 2.1e-72 yugU S Uncharacterised protein family UPF0047
PPHEPGDA_03125 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
PPHEPGDA_03126 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
PPHEPGDA_03127 1.4e-116 yugP S Zn-dependent protease
PPHEPGDA_03128 3.7e-36
PPHEPGDA_03129 1.1e-53 mstX S Membrane-integrating protein Mistic
PPHEPGDA_03130 3.1e-181 yugO P COG1226 Kef-type K transport systems
PPHEPGDA_03131 1.3e-72 yugN S YugN-like family
PPHEPGDA_03133 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
PPHEPGDA_03134 1.9e-225 yugK C Dehydrogenase
PPHEPGDA_03135 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
PPHEPGDA_03136 1.1e-34 yuzA S Domain of unknown function (DUF378)
PPHEPGDA_03137 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
PPHEPGDA_03138 2.1e-199 yugH 2.6.1.1 E Aminotransferase
PPHEPGDA_03139 1.6e-85 alaR K Transcriptional regulator
PPHEPGDA_03140 4.9e-156 yugF I Hydrolase
PPHEPGDA_03141 4.6e-39 yugE S Domain of unknown function (DUF1871)
PPHEPGDA_03142 2.9e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PPHEPGDA_03143 2.3e-232 T PhoQ Sensor
PPHEPGDA_03144 1.8e-68 kapB G Kinase associated protein B
PPHEPGDA_03145 4.2e-115 kapD L the KinA pathway to sporulation
PPHEPGDA_03147 3.8e-185 yuxJ EGP Major facilitator Superfamily
PPHEPGDA_03148 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
PPHEPGDA_03149 3.1e-74 yuxK S protein conserved in bacteria
PPHEPGDA_03150 6.3e-78 yufK S Family of unknown function (DUF5366)
PPHEPGDA_03151 3.8e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
PPHEPGDA_03152 1.5e-124 dcuR T COG4565 Response regulator of citrate malate metabolism
PPHEPGDA_03153 4.9e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
PPHEPGDA_03154 5.4e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PPHEPGDA_03155 1.3e-182 yufP S Belongs to the binding-protein-dependent transport system permease family
PPHEPGDA_03156 5e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
PPHEPGDA_03157 8.2e-233 maeN C COG3493 Na citrate symporter
PPHEPGDA_03158 5e-15
PPHEPGDA_03159 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
PPHEPGDA_03160 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PPHEPGDA_03161 3.4e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PPHEPGDA_03162 3.9e-260 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PPHEPGDA_03163 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PPHEPGDA_03164 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
PPHEPGDA_03165 6.7e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
PPHEPGDA_03166 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
PPHEPGDA_03167 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_03168 0.0 comP 2.7.13.3 T Histidine kinase
PPHEPGDA_03170 1.5e-127 comQ H Belongs to the FPP GGPP synthase family
PPHEPGDA_03173 3.8e-23 yuzC
PPHEPGDA_03174 1.8e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
PPHEPGDA_03175 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PPHEPGDA_03176 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
PPHEPGDA_03177 1.8e-66 yueI S Protein of unknown function (DUF1694)
PPHEPGDA_03178 7.4e-39 yueH S YueH-like protein
PPHEPGDA_03179 2.5e-30 yueG S Spore germination protein gerPA/gerPF
PPHEPGDA_03180 3.2e-190 yueF S transporter activity
PPHEPGDA_03181 5.2e-71 S Protein of unknown function (DUF2283)
PPHEPGDA_03182 2.2e-24 S Protein of unknown function (DUF2642)
PPHEPGDA_03183 1.1e-95 yueE S phosphohydrolase
PPHEPGDA_03184 5.4e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_03185 3.3e-64 yueC S Family of unknown function (DUF5383)
PPHEPGDA_03186 0.0 esaA S type VII secretion protein EsaA
PPHEPGDA_03187 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
PPHEPGDA_03188 2.4e-208 essB S WXG100 protein secretion system (Wss), protein YukC
PPHEPGDA_03189 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
PPHEPGDA_03190 2.8e-45 esxA S Belongs to the WXG100 family
PPHEPGDA_03191 4.2e-228 yukF QT Transcriptional regulator
PPHEPGDA_03192 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
PPHEPGDA_03193 4.5e-131 yukJ S Uncharacterized conserved protein (DUF2278)
PPHEPGDA_03194 1.4e-35 mbtH S MbtH-like protein
PPHEPGDA_03195 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_03196 9.9e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
PPHEPGDA_03197 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
PPHEPGDA_03198 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
PPHEPGDA_03199 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03200 1.1e-166 besA S Putative esterase
PPHEPGDA_03201 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
PPHEPGDA_03202 1.1e-93 bioY S Biotin biosynthesis protein
PPHEPGDA_03203 3.9e-211 yuiF S antiporter
PPHEPGDA_03204 1e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
PPHEPGDA_03205 1.2e-77 yuiD S protein conserved in bacteria
PPHEPGDA_03206 4.7e-117 yuiC S protein conserved in bacteria
PPHEPGDA_03207 1.1e-26 yuiB S Putative membrane protein
PPHEPGDA_03208 3.6e-235 yumB 1.6.99.3 C NADH dehydrogenase
PPHEPGDA_03209 1e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
PPHEPGDA_03211 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PPHEPGDA_03212 3.8e-116 paiB K Putative FMN-binding domain
PPHEPGDA_03213 6.7e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_03214 3e-22 S Short C-terminal domain
PPHEPGDA_03215 2.9e-305 D Phage tail tape measure protein
PPHEPGDA_03222 2.2e-18
PPHEPGDA_03223 3.8e-88
PPHEPGDA_03229 4.9e-56
PPHEPGDA_03230 5.7e-11 K sequence-specific DNA binding
PPHEPGDA_03232 6.7e-13 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_03233 4.4e-68 L Integrase
PPHEPGDA_03234 4.3e-103 S Helix-turn-helix domain
PPHEPGDA_03235 3.1e-102 L Belongs to the 'phage' integrase family
PPHEPGDA_03236 3.7e-63 erpA S Belongs to the HesB IscA family
PPHEPGDA_03237 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PPHEPGDA_03238 1.3e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PPHEPGDA_03239 3.2e-39 yuzB S Belongs to the UPF0349 family
PPHEPGDA_03240 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
PPHEPGDA_03241 3.3e-55 yuzD S protein conserved in bacteria
PPHEPGDA_03242 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
PPHEPGDA_03243 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
PPHEPGDA_03244 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PPHEPGDA_03245 2.6e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PPHEPGDA_03246 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
PPHEPGDA_03247 2.9e-198 yutH S Spore coat protein
PPHEPGDA_03248 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
PPHEPGDA_03249 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PPHEPGDA_03250 1e-75 yutE S Protein of unknown function DUF86
PPHEPGDA_03251 9.7e-48 yutD S protein conserved in bacteria
PPHEPGDA_03252 1.8e-110 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
PPHEPGDA_03253 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PPHEPGDA_03254 1.3e-195 lytH M Peptidase, M23
PPHEPGDA_03255 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
PPHEPGDA_03256 1.1e-47 yunC S Domain of unknown function (DUF1805)
PPHEPGDA_03257 3.2e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PPHEPGDA_03258 1.3e-140 yunE S membrane transporter protein
PPHEPGDA_03259 4.3e-171 yunF S Protein of unknown function DUF72
PPHEPGDA_03260 2.8e-60 yunG
PPHEPGDA_03261 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
PPHEPGDA_03262 3.5e-299 pucR QT COG2508 Regulator of polyketide synthase expression
PPHEPGDA_03263 2.8e-233 pbuX F Permease family
PPHEPGDA_03264 4.3e-215 pbuX F xanthine
PPHEPGDA_03265 3.7e-279 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
PPHEPGDA_03266 3.5e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
PPHEPGDA_03268 9e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
PPHEPGDA_03269 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
PPHEPGDA_03270 6.6e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
PPHEPGDA_03271 2.2e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
PPHEPGDA_03272 6.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
PPHEPGDA_03273 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
PPHEPGDA_03274 6.4e-232 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
PPHEPGDA_03275 2.7e-168 bsn L Ribonuclease
PPHEPGDA_03276 2.9e-204 msmX P Belongs to the ABC transporter superfamily
PPHEPGDA_03277 3.3e-135 yurK K UTRA
PPHEPGDA_03278 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
PPHEPGDA_03279 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
PPHEPGDA_03280 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
PPHEPGDA_03281 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
PPHEPGDA_03282 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
PPHEPGDA_03283 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
PPHEPGDA_03284 9.6e-203 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
PPHEPGDA_03286 1e-41
PPHEPGDA_03287 1.4e-45 L transposase activity
PPHEPGDA_03288 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
PPHEPGDA_03289 2.4e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_03290 4.2e-08
PPHEPGDA_03291 2.1e-12
PPHEPGDA_03292 1.2e-297 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
PPHEPGDA_03293 1.4e-83 S SMI1-KNR4 cell-wall
PPHEPGDA_03294 1.9e-111 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_03295 4.6e-57 S Bacteriophage holin family
PPHEPGDA_03297 1.1e-15
PPHEPGDA_03298 8.9e-178 S Domain of unknown function (DUF2479)
PPHEPGDA_03299 1.9e-260
PPHEPGDA_03300 3.4e-112 mur1 NU Prophage endopeptidase tail
PPHEPGDA_03301 2.7e-45 S Phage tail protein
PPHEPGDA_03302 2.7e-294 D Phage tail tape measure protein
PPHEPGDA_03305 3.1e-27 S Pfam:Phage_TTP_1
PPHEPGDA_03306 1.2e-09
PPHEPGDA_03307 4.9e-29 S Bacteriophage HK97-gp10, putative tail-component
PPHEPGDA_03308 1e-27 S Phage head-tail joining protein
PPHEPGDA_03309 2.6e-22 S Phage gp6-like head-tail connector protein
PPHEPGDA_03310 3e-07
PPHEPGDA_03311 1.5e-129 S capsid protein
PPHEPGDA_03312 4.2e-72 pi136 S Caudovirus prohead serine protease
PPHEPGDA_03313 1.3e-171 S portal protein
PPHEPGDA_03315 1.6e-148 terL S Terminase
PPHEPGDA_03316 6e-56 terS L Terminase, small subunit
PPHEPGDA_03318 5e-18 S HNH endonuclease
PPHEPGDA_03322 2.6e-73 L Phage integrase family
PPHEPGDA_03323 7.4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
PPHEPGDA_03327 5e-07
PPHEPGDA_03328 2.6e-49 S dUTPase
PPHEPGDA_03331 6.9e-26
PPHEPGDA_03337 1.1e-31
PPHEPGDA_03339 2.4e-52 dnaC L DNA replication protein
PPHEPGDA_03340 3.6e-69 L dnaD_dom DnaD domain protein
PPHEPGDA_03342 9.9e-16
PPHEPGDA_03344 5e-45 K Helix-turn-helix XRE-family like proteins
PPHEPGDA_03347 9.5e-44
PPHEPGDA_03348 1e-118 int L Belongs to the 'phage' integrase family
PPHEPGDA_03349 3.5e-271 sufB O FeS cluster assembly
PPHEPGDA_03350 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
PPHEPGDA_03351 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PPHEPGDA_03352 1.7e-243 sufD O assembly protein SufD
PPHEPGDA_03353 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PPHEPGDA_03354 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
PPHEPGDA_03355 5.5e-147 metQ P Belongs to the NlpA lipoprotein family
PPHEPGDA_03356 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
PPHEPGDA_03357 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PPHEPGDA_03358 3.2e-56 yusD S SCP-2 sterol transfer family
PPHEPGDA_03359 1.2e-54 traF CO Thioredoxin
PPHEPGDA_03360 1.4e-72 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
PPHEPGDA_03361 2.4e-39 yusG S Protein of unknown function (DUF2553)
PPHEPGDA_03362 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
PPHEPGDA_03363 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
PPHEPGDA_03364 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
PPHEPGDA_03365 1.1e-214 fadA 2.3.1.16 I Belongs to the thiolase family
PPHEPGDA_03366 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
PPHEPGDA_03367 8.1e-09 S YuzL-like protein
PPHEPGDA_03368 1.2e-163 fadM E Proline dehydrogenase
PPHEPGDA_03369 5.1e-40
PPHEPGDA_03370 5.4e-53 yusN M Coat F domain
PPHEPGDA_03371 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
PPHEPGDA_03372 4.2e-292 yusP P Major facilitator superfamily
PPHEPGDA_03373 3.3e-62 yusQ S Tautomerase enzyme
PPHEPGDA_03374 8.5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03375 8.2e-157 yusT K LysR substrate binding domain
PPHEPGDA_03376 6.6e-47 yusU S Protein of unknown function (DUF2573)
PPHEPGDA_03377 2.3e-153 yusV 3.6.3.34 HP ABC transporter
PPHEPGDA_03378 2.5e-66 S YusW-like protein
PPHEPGDA_03379 6e-115 pepF2 E COG1164 Oligoendopeptidase F
PPHEPGDA_03380 1.1e-220 L Transposase
PPHEPGDA_03381 9.9e-119 L PhoH-like protein
PPHEPGDA_03382 9.5e-140 pepF2 E COG1164 Oligoendopeptidase F
PPHEPGDA_03384 1.3e-23 ecsB U ABC transporter
PPHEPGDA_03385 2.2e-75 ecsA V ABC superfamily ATP binding cassette transporter ABC protein
PPHEPGDA_03386 1.1e-25 Q methyltransferase
PPHEPGDA_03387 8.6e-27 EGP Major facilitator Superfamily
PPHEPGDA_03388 7.1e-07 K PFAM Acetyltransferase (GNAT) family
PPHEPGDA_03389 6.4e-36 2.6.1.76 E Psort location Cytoplasmic, score
PPHEPGDA_03390 6.8e-19 S Evidence 4 Homologs of previously reported genes of
PPHEPGDA_03391 1.1e-24
PPHEPGDA_03392 1.2e-129 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
PPHEPGDA_03393 3.6e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03394 1.2e-79 dps P Ferritin-like domain
PPHEPGDA_03395 8.9e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PPHEPGDA_03396 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_03397 1.7e-249 cssS 2.7.13.3 T PhoQ Sensor
PPHEPGDA_03398 4.3e-158 yuxN K Transcriptional regulator
PPHEPGDA_03399 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PPHEPGDA_03400 3.9e-24 S Protein of unknown function (DUF3970)
PPHEPGDA_03401 2.6e-245 gerAA EG Spore germination protein
PPHEPGDA_03402 3.8e-196 gerAB E Spore germination protein
PPHEPGDA_03403 5.3e-177 gerAC S Spore germination B3/ GerAC like, C-terminal
PPHEPGDA_03404 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_03405 1.6e-186 vraS 2.7.13.3 T Histidine kinase
PPHEPGDA_03406 2.8e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
PPHEPGDA_03407 9.6e-126 liaG S Putative adhesin
PPHEPGDA_03408 2.3e-103 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
PPHEPGDA_03409 2.8e-61 liaI S membrane
PPHEPGDA_03410 4.8e-227 yvqJ EGP Major facilitator Superfamily
PPHEPGDA_03411 5.1e-99 yvqK 2.5.1.17 S Adenosyltransferase
PPHEPGDA_03412 7.1e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
PPHEPGDA_03413 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_03414 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PPHEPGDA_03415 1.7e-42 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03416 5.7e-83 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03417 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
PPHEPGDA_03418 0.0 T PhoQ Sensor
PPHEPGDA_03419 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_03420 3.6e-22
PPHEPGDA_03421 2.3e-96 yvrI K RNA polymerase
PPHEPGDA_03422 2.4e-19 S YvrJ protein family
PPHEPGDA_03423 3.1e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
PPHEPGDA_03424 1.3e-64 yvrL S Regulatory protein YrvL
PPHEPGDA_03425 5.3e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
PPHEPGDA_03426 6e-123 macB V ABC transporter, ATP-binding protein
PPHEPGDA_03427 2e-174 M Efflux transporter rnd family, mfp subunit
PPHEPGDA_03428 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
PPHEPGDA_03429 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_03430 1.1e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PPHEPGDA_03431 7.6e-177 fhuD P ABC transporter
PPHEPGDA_03433 1.8e-235 yvsH E Arginine ornithine antiporter
PPHEPGDA_03434 6.5e-16 S Small spore protein J (Spore_SspJ)
PPHEPGDA_03435 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
PPHEPGDA_03436 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PPHEPGDA_03437 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
PPHEPGDA_03438 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
PPHEPGDA_03439 3.1e-119 modB P COG4149 ABC-type molybdate transport system, permease component
PPHEPGDA_03440 1.1e-155 yvgN S reductase
PPHEPGDA_03441 2.1e-85 yvgO
PPHEPGDA_03442 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
PPHEPGDA_03443 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
PPHEPGDA_03444 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PPHEPGDA_03445 0.0 helD 3.6.4.12 L DNA helicase
PPHEPGDA_03447 1.6e-106 yvgT S membrane
PPHEPGDA_03448 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
PPHEPGDA_03449 1.6e-104 bdbD O Thioredoxin
PPHEPGDA_03450 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
PPHEPGDA_03451 0.0 copA 3.6.3.54 P P-type ATPase
PPHEPGDA_03452 3.8e-28 copZ P Copper resistance protein CopZ
PPHEPGDA_03453 2.2e-48 csoR S transcriptional
PPHEPGDA_03454 6.9e-195 yvaA 1.1.1.371 S Oxidoreductase
PPHEPGDA_03455 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PPHEPGDA_03456 0.0 yvaC S Fusaric acid resistance protein-like
PPHEPGDA_03457 4.5e-48 yvaD S Family of unknown function (DUF5360)
PPHEPGDA_03458 3.4e-53 yvaE P Small Multidrug Resistance protein
PPHEPGDA_03459 1.1e-98 K Bacterial regulatory proteins, tetR family
PPHEPGDA_03460 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_03462 3.6e-12
PPHEPGDA_03463 2.8e-179 A Pre-toxin TG
PPHEPGDA_03464 2.4e-07 S Immunity protein 50
PPHEPGDA_03466 1.2e-110 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_03467 2.7e-57 S Bacteriophage holin family
PPHEPGDA_03469 3.7e-16
PPHEPGDA_03470 1.5e-192 S Domain of unknown function (DUF2479)
PPHEPGDA_03471 7.2e-257
PPHEPGDA_03472 4.2e-242 NU Prophage endopeptidase tail
PPHEPGDA_03473 2.2e-111 S Phage tail protein
PPHEPGDA_03474 0.0 S peptidoglycan catabolic process
PPHEPGDA_03475 4.8e-10
PPHEPGDA_03476 2e-26
PPHEPGDA_03477 1.5e-61
PPHEPGDA_03478 1.9e-30
PPHEPGDA_03479 2.3e-47 S Bacteriophage HK97-gp10, putative tail-component
PPHEPGDA_03480 1.1e-24 S Phage gp6-like head-tail connector protein
PPHEPGDA_03481 1.3e-26 S peptidoglycan catabolic process
PPHEPGDA_03483 2.9e-181 S capsid protein
PPHEPGDA_03484 1e-105 S peptidase activity
PPHEPGDA_03485 2.3e-213 S Phage portal protein
PPHEPGDA_03486 2.2e-10
PPHEPGDA_03487 3.5e-220 S Phage Terminase
PPHEPGDA_03488 5.1e-69 S Phage terminase, small subunit
PPHEPGDA_03489 1.2e-09
PPHEPGDA_03490 2.2e-59 S HNH endonuclease
PPHEPGDA_03492 9.7e-21
PPHEPGDA_03493 2.3e-15 S PIN domain
PPHEPGDA_03494 6.4e-61 L Phage integrase family
PPHEPGDA_03495 1.4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
PPHEPGDA_03497 3.8e-11 S YopX protein
PPHEPGDA_03499 1.1e-46 S dUTPase
PPHEPGDA_03501 7.7e-25
PPHEPGDA_03504 2e-07 yqaO S Phage-like element PBSX protein XtrA
PPHEPGDA_03508 1.9e-31
PPHEPGDA_03509 2e-43 dnaC L IstB-like ATP binding protein
PPHEPGDA_03510 9e-71 ybl78 L Conserved phage C-terminus (Phg_2220_C)
PPHEPGDA_03512 8.6e-11 S sequence-specific DNA binding
PPHEPGDA_03513 3.6e-07 acoR T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
PPHEPGDA_03514 2.5e-44 K Helix-turn-helix XRE-family like proteins
PPHEPGDA_03517 5.2e-60
PPHEPGDA_03518 3.1e-34 S Phage integrase family
PPHEPGDA_03519 4.5e-66 S Phage integrase family
PPHEPGDA_03521 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PPHEPGDA_03522 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PPHEPGDA_03523 5.6e-143 est 3.1.1.1 S Carboxylesterase
PPHEPGDA_03524 2.4e-23 secG U Preprotein translocase subunit SecG
PPHEPGDA_03525 1.5e-151 yvaM S Serine aminopeptidase, S33
PPHEPGDA_03526 9.8e-36 yvzC K Transcriptional
PPHEPGDA_03527 3.1e-69 K transcriptional
PPHEPGDA_03528 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_03529 2.2e-54 yodB K transcriptional
PPHEPGDA_03530 3e-216 NT chemotaxis protein
PPHEPGDA_03531 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PPHEPGDA_03532 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PPHEPGDA_03533 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PPHEPGDA_03534 9.8e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PPHEPGDA_03535 1.9e-60 yvbF K Belongs to the GbsR family
PPHEPGDA_03536 4.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
PPHEPGDA_03537 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PPHEPGDA_03538 1.3e-111 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
PPHEPGDA_03539 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
PPHEPGDA_03540 3.5e-97 yvbF K Belongs to the GbsR family
PPHEPGDA_03541 6e-101 yvbG U UPF0056 membrane protein
PPHEPGDA_03542 8.6e-113 yvbH S YvbH-like oligomerisation region
PPHEPGDA_03543 3.6e-123 exoY M Membrane
PPHEPGDA_03544 0.0 tcaA S response to antibiotic
PPHEPGDA_03545 3.8e-81 yvbK 3.1.3.25 K acetyltransferase
PPHEPGDA_03546 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PPHEPGDA_03547 3.1e-297 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
PPHEPGDA_03548 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PPHEPGDA_03549 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PPHEPGDA_03550 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PPHEPGDA_03551 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PPHEPGDA_03552 1.6e-252 araE EGP Major facilitator Superfamily
PPHEPGDA_03553 5.5e-203 araR K transcriptional
PPHEPGDA_03554 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPHEPGDA_03555 5.1e-159 yvbU K Transcriptional regulator
PPHEPGDA_03556 7.2e-156 yvbV EG EamA-like transporter family
PPHEPGDA_03557 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
PPHEPGDA_03558 1.7e-84 yvbX S Glycosyl hydrolase
PPHEPGDA_03559 3.3e-36 yvbX S Glycosyl hydrolase
PPHEPGDA_03560 1.2e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PPHEPGDA_03561 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
PPHEPGDA_03562 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
PPHEPGDA_03563 1.3e-44 S Protein of unknown function (DUF2812)
PPHEPGDA_03564 2.6e-31 K Transcriptional regulator PadR-like family
PPHEPGDA_03565 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_03566 2.1e-197 desK 2.7.13.3 T Histidine kinase
PPHEPGDA_03567 2e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
PPHEPGDA_03568 8.9e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
PPHEPGDA_03569 2.6e-157 rsbQ S Alpha/beta hydrolase family
PPHEPGDA_03570 7.2e-196 rsbU 3.1.3.3 T response regulator
PPHEPGDA_03571 1.9e-250 galA 3.2.1.89 G arabinogalactan
PPHEPGDA_03572 0.0 lacA 3.2.1.23 G beta-galactosidase
PPHEPGDA_03573 7.2e-150 ganQ P transport
PPHEPGDA_03574 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
PPHEPGDA_03575 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
PPHEPGDA_03576 1.4e-184 lacR K Transcriptional regulator
PPHEPGDA_03577 2.7e-113 yvfI K COG2186 Transcriptional regulators
PPHEPGDA_03578 5.3e-306 yvfH C L-lactate permease
PPHEPGDA_03579 1.6e-241 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
PPHEPGDA_03580 1e-31 yvfG S YvfG protein
PPHEPGDA_03581 2.2e-187 yvfF GM Exopolysaccharide biosynthesis protein
PPHEPGDA_03582 6.9e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
PPHEPGDA_03583 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
PPHEPGDA_03584 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PPHEPGDA_03585 4.3e-254 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_03586 3.6e-188 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
PPHEPGDA_03587 3.5e-202 epsI GM pyruvyl transferase
PPHEPGDA_03588 2.4e-192 epsH GT2 S Glycosyltransferase like family 2
PPHEPGDA_03589 1.8e-206 epsG S EpsG family
PPHEPGDA_03590 6.4e-218 epsF GT4 M Glycosyl transferases group 1
PPHEPGDA_03591 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
PPHEPGDA_03592 5.2e-220 epsD GT4 M Glycosyl transferase 4-like
PPHEPGDA_03593 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
PPHEPGDA_03594 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
PPHEPGDA_03595 4e-122 ywqC M biosynthesis protein
PPHEPGDA_03596 6.3e-76 slr K transcriptional
PPHEPGDA_03597 4.8e-279 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
PPHEPGDA_03599 4.6e-93 padC Q Phenolic acid decarboxylase
PPHEPGDA_03600 1.9e-46 MA20_18690 S Protein of unknown function (DUF3237)
PPHEPGDA_03601 6.1e-16 MA20_18690 S Protein of unknown function (DUF3237)
PPHEPGDA_03602 3e-122 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
PPHEPGDA_03603 1.2e-177 pbpE V Beta-lactamase
PPHEPGDA_03604 1.5e-63 pbpE V Beta-lactamase
PPHEPGDA_03605 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
PPHEPGDA_03606 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
PPHEPGDA_03607 1.8e-295 yveA E amino acid
PPHEPGDA_03608 7.4e-106 yvdT K Transcriptional regulator
PPHEPGDA_03609 1.5e-50 ykkC P Small Multidrug Resistance protein
PPHEPGDA_03610 7.1e-50 sugE P Small Multidrug Resistance protein
PPHEPGDA_03611 3.9e-72 yvdQ S Protein of unknown function (DUF3231)
PPHEPGDA_03613 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PPHEPGDA_03614 5e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
PPHEPGDA_03615 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
PPHEPGDA_03616 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
PPHEPGDA_03617 2.6e-113 malA S Protein of unknown function (DUF1189)
PPHEPGDA_03618 3.9e-148 malD P transport
PPHEPGDA_03619 8.5e-243 malC P COG1175 ABC-type sugar transport systems, permease components
PPHEPGDA_03620 1.3e-125 mdxE G COG2182 Maltose-binding periplasmic proteins domains
PPHEPGDA_03621 7.5e-84 mdxE G COG2182 Maltose-binding periplasmic proteins domains
PPHEPGDA_03622 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
PPHEPGDA_03623 7.9e-174 yvdE K Transcriptional regulator
PPHEPGDA_03624 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
PPHEPGDA_03625 5.9e-29 yvdC S MazG nucleotide pyrophosphohydrolase domain
PPHEPGDA_03626 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
PPHEPGDA_03627 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
PPHEPGDA_03628 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PPHEPGDA_03629 0.0 yxdM V ABC transporter (permease)
PPHEPGDA_03630 5.6e-141 yvcR V ABC transporter, ATP-binding protein
PPHEPGDA_03631 3.2e-195 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PPHEPGDA_03632 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_03633 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
PPHEPGDA_03634 1.6e-36 crh G Phosphocarrier protein Chr
PPHEPGDA_03635 4.1e-170 whiA K May be required for sporulation
PPHEPGDA_03636 3.6e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PPHEPGDA_03637 5.7e-166 rapZ S Displays ATPase and GTPase activities
PPHEPGDA_03638 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
PPHEPGDA_03639 2.8e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PPHEPGDA_03640 1.1e-97 usp CBM50 M protein conserved in bacteria
PPHEPGDA_03641 8.4e-276 S COG0457 FOG TPR repeat
PPHEPGDA_03642 0.0 msbA2 3.6.3.44 V ABC transporter
PPHEPGDA_03644 4.5e-253
PPHEPGDA_03645 2.3e-69
PPHEPGDA_03646 2.8e-111 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
PPHEPGDA_03647 8.1e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PPHEPGDA_03648 2.9e-131 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PPHEPGDA_03649 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PPHEPGDA_03650 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PPHEPGDA_03651 3.2e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PPHEPGDA_03652 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PPHEPGDA_03653 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PPHEPGDA_03654 1.1e-138 yvpB NU protein conserved in bacteria
PPHEPGDA_03655 1.3e-119 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
PPHEPGDA_03656 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
PPHEPGDA_03657 2e-115 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
PPHEPGDA_03658 8.1e-163 yvoD P COG0370 Fe2 transport system protein B
PPHEPGDA_03659 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PPHEPGDA_03660 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PPHEPGDA_03661 2e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PPHEPGDA_03662 1.5e-127 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PPHEPGDA_03663 3.6e-134 yvoA K transcriptional
PPHEPGDA_03664 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
PPHEPGDA_03665 1.2e-50 yvlD S Membrane
PPHEPGDA_03666 2.6e-26 pspB KT PspC domain
PPHEPGDA_03667 3.4e-168 yvlB S Putative adhesin
PPHEPGDA_03668 8e-49 yvlA
PPHEPGDA_03669 5.7e-33 yvkN
PPHEPGDA_03670 4.7e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PPHEPGDA_03671 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PPHEPGDA_03672 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PPHEPGDA_03673 1.2e-30 csbA S protein conserved in bacteria
PPHEPGDA_03674 0.0 yvkC 2.7.9.2 GT Phosphotransferase
PPHEPGDA_03675 7e-101 yvkB K Transcriptional regulator
PPHEPGDA_03676 9.6e-226 yvkA EGP Major facilitator Superfamily
PPHEPGDA_03677 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PPHEPGDA_03678 1.8e-72 swrA S Swarming motility protein
PPHEPGDA_03679 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
PPHEPGDA_03680 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PPHEPGDA_03681 2.7e-123 ftsE D cell division ATP-binding protein FtsE
PPHEPGDA_03682 2e-55 cccB C COG2010 Cytochrome c, mono- and diheme variants
PPHEPGDA_03683 7.1e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
PPHEPGDA_03684 3.9e-184 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PPHEPGDA_03685 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PPHEPGDA_03686 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PPHEPGDA_03687 4.6e-51
PPHEPGDA_03688 1.9e-08 fliT S bacterial-type flagellum organization
PPHEPGDA_03689 6.5e-69 fliS N flagellar protein FliS
PPHEPGDA_03690 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
PPHEPGDA_03691 1.2e-55 flaG N flagellar protein FlaG
PPHEPGDA_03692 1.4e-122 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
PPHEPGDA_03693 5.7e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
PPHEPGDA_03694 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
PPHEPGDA_03695 1.3e-49 yviE
PPHEPGDA_03696 1.3e-154 flgL N Belongs to the bacterial flagellin family
PPHEPGDA_03697 1.6e-264 flgK N flagellar hook-associated protein
PPHEPGDA_03698 4.1e-78 flgN NOU FlgN protein
PPHEPGDA_03699 4.7e-39 flgM KNU Negative regulator of flagellin synthesis
PPHEPGDA_03700 4.6e-73 yvyF S flagellar protein
PPHEPGDA_03701 1.2e-126 comFC S Phosphoribosyl transferase domain
PPHEPGDA_03702 5.7e-46 comFB S Late competence development protein ComFB
PPHEPGDA_03703 6.4e-265 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PPHEPGDA_03704 2.1e-154 degV S protein conserved in bacteria
PPHEPGDA_03705 5.8e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PPHEPGDA_03706 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
PPHEPGDA_03707 4.9e-106 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
PPHEPGDA_03708 1.3e-113 yvhJ K Transcriptional regulator
PPHEPGDA_03712 4.5e-42 S Psort location CytoplasmicMembrane, score
PPHEPGDA_03714 1e-28 S CytoplasmicMembrane, score 9.99
PPHEPGDA_03715 6.7e-79 V ABC transporter, ATP-binding protein
PPHEPGDA_03716 1e-13
PPHEPGDA_03717 3.4e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
PPHEPGDA_03718 3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
PPHEPGDA_03719 4.4e-135 tuaG GT2 M Glycosyltransferase like family 2
PPHEPGDA_03720 2.7e-107 tuaF M protein involved in exopolysaccharide biosynthesis
PPHEPGDA_03721 3.2e-243 tuaE M Teichuronic acid biosynthesis protein
PPHEPGDA_03723 3.2e-237 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PPHEPGDA_03724 4.2e-201 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
PPHEPGDA_03725 1.3e-231 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
PPHEPGDA_03726 4.7e-117 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
PPHEPGDA_03727 2.3e-260 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
PPHEPGDA_03728 0.0 lytB 3.5.1.28 D Stage II sporulation protein
PPHEPGDA_03729 2.9e-11
PPHEPGDA_03730 5e-17 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
PPHEPGDA_03731 8.5e-207 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PPHEPGDA_03732 2.1e-160 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PPHEPGDA_03733 6.1e-10 L COG2963 Transposase and inactivated derivatives
PPHEPGDA_03734 6.3e-160 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PPHEPGDA_03735 4.1e-134 tagG GM Transport permease protein
PPHEPGDA_03737 4.1e-281 tagF2 2.7.8.12 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
PPHEPGDA_03738 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PPHEPGDA_03739 4.9e-69 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
PPHEPGDA_03740 6.6e-142 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
PPHEPGDA_03741 4.6e-192 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
PPHEPGDA_03742 2.8e-213 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
PPHEPGDA_03743 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
PPHEPGDA_03744 1e-244 gerBA EG Spore germination protein
PPHEPGDA_03745 7.3e-187 gerBB E Spore germination protein
PPHEPGDA_03746 1.2e-200 gerAC S Spore germination protein
PPHEPGDA_03747 7.2e-204 ywtG EGP Major facilitator Superfamily
PPHEPGDA_03748 3.5e-140 ywtF K Transcriptional regulator
PPHEPGDA_03749 5e-159 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
PPHEPGDA_03750 2.9e-238 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
PPHEPGDA_03751 3.6e-21 ywtC
PPHEPGDA_03752 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
PPHEPGDA_03753 8.6e-70 pgsC S biosynthesis protein
PPHEPGDA_03754 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
PPHEPGDA_03755 3e-176 rbsR K transcriptional
PPHEPGDA_03756 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PPHEPGDA_03757 1.5e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
PPHEPGDA_03758 5.2e-273 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
PPHEPGDA_03759 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
PPHEPGDA_03760 1.2e-158 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
PPHEPGDA_03761 7.3e-92 batE T Sh3 type 3 domain protein
PPHEPGDA_03762 8e-48 ywsA S Protein of unknown function (DUF3892)
PPHEPGDA_03763 9.7e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
PPHEPGDA_03764 4.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
PPHEPGDA_03765 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PPHEPGDA_03766 2.5e-169 alsR K LysR substrate binding domain
PPHEPGDA_03767 1.8e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
PPHEPGDA_03768 2.2e-125 ywrJ
PPHEPGDA_03769 2.6e-123 cotB
PPHEPGDA_03770 6.2e-207 cotH M Spore Coat
PPHEPGDA_03771 1.3e-12
PPHEPGDA_03772 6.9e-110 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PPHEPGDA_03773 5e-54 S Domain of unknown function (DUF4181)
PPHEPGDA_03774 9.4e-305 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
PPHEPGDA_03775 8e-82 ywrC K Transcriptional regulator
PPHEPGDA_03776 1.6e-103 ywrB P Chromate transporter
PPHEPGDA_03777 1.4e-87 ywrA P COG2059 Chromate transport protein ChrA
PPHEPGDA_03779 4.8e-99 ywqN S NAD(P)H-dependent
PPHEPGDA_03780 1.4e-161 K Transcriptional regulator
PPHEPGDA_03781 4.9e-116 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
PPHEPGDA_03782 3.9e-25
PPHEPGDA_03783 3.3e-29 S protein secretion by the type VII secretion system
PPHEPGDA_03784 1.7e-78 ywqJ S Pre-toxin TG
PPHEPGDA_03785 5.2e-17
PPHEPGDA_03786 6.1e-43
PPHEPGDA_03787 2e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
PPHEPGDA_03788 3.9e-38 ywqI S Family of unknown function (DUF5344)
PPHEPGDA_03789 9.7e-23 S Domain of unknown function (DUF5082)
PPHEPGDA_03790 5.1e-150 ywqG S Domain of unknown function (DUF1963)
PPHEPGDA_03791 1.1e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PPHEPGDA_03792 6.7e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
PPHEPGDA_03793 2.2e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
PPHEPGDA_03794 2e-116 ywqC M biosynthesis protein
PPHEPGDA_03795 1.2e-17
PPHEPGDA_03796 1e-306 ywqB S SWIM zinc finger
PPHEPGDA_03797 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
PPHEPGDA_03798 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
PPHEPGDA_03799 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
PPHEPGDA_03800 9.8e-58 ssbB L Single-stranded DNA-binding protein
PPHEPGDA_03801 1.9e-65 ywpG
PPHEPGDA_03802 6.9e-66 ywpF S YwpF-like protein
PPHEPGDA_03803 5.2e-50 srtA 3.4.22.70 M Sortase family
PPHEPGDA_03804 2.1e-144 ywpD T Histidine kinase
PPHEPGDA_03805 1.1e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PPHEPGDA_03806 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PPHEPGDA_03807 7.5e-197 S aspartate phosphatase
PPHEPGDA_03808 2.6e-141 flhP N flagellar basal body
PPHEPGDA_03809 3.2e-123 flhO N flagellar basal body
PPHEPGDA_03810 3.5e-180 mbl D Rod shape-determining protein
PPHEPGDA_03811 3e-44 spoIIID K Stage III sporulation protein D
PPHEPGDA_03812 2.1e-70 ywoH K COG1846 Transcriptional regulators
PPHEPGDA_03813 1.1e-209 ywoG EGP Major facilitator Superfamily
PPHEPGDA_03814 3.3e-131 ywoF P Right handed beta helix region
PPHEPGDA_03815 2e-57 ywoF P Right handed beta helix region
PPHEPGDA_03816 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
PPHEPGDA_03817 2.7e-239 ywoD EGP Major facilitator superfamily
PPHEPGDA_03818 6.8e-104 phzA Q Isochorismatase family
PPHEPGDA_03819 4.1e-75
PPHEPGDA_03821 2.8e-224 amt P Ammonium transporter
PPHEPGDA_03822 1.6e-58 nrgB K Belongs to the P(II) protein family
PPHEPGDA_03823 7.7e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
PPHEPGDA_03824 5.6e-71 ywnJ S VanZ like family
PPHEPGDA_03825 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
PPHEPGDA_03826 1e-87 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
PPHEPGDA_03827 3.7e-08 ywnC S Family of unknown function (DUF5362)
PPHEPGDA_03828 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
PPHEPGDA_03829 2.2e-70 ywnF S Family of unknown function (DUF5392)
PPHEPGDA_03830 7.8e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PPHEPGDA_03831 2.1e-140 mta K transcriptional
PPHEPGDA_03832 2.6e-59 ywnC S Family of unknown function (DUF5362)
PPHEPGDA_03833 1.5e-86 ywnB S NAD(P)H-binding
PPHEPGDA_03834 5.9e-14 ywnB S NAD(P)H-binding
PPHEPGDA_03835 1.7e-64 ywnA K Transcriptional regulator
PPHEPGDA_03836 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PPHEPGDA_03837 2.2e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PPHEPGDA_03838 1.4e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PPHEPGDA_03839 3.8e-11 csbD K CsbD-like
PPHEPGDA_03840 3e-84 ywmF S Peptidase M50
PPHEPGDA_03841 7.9e-104 S response regulator aspartate phosphatase
PPHEPGDA_03842 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
PPHEPGDA_03843 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
PPHEPGDA_03845 2.7e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
PPHEPGDA_03846 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
PPHEPGDA_03847 7.5e-178 spoIID D Stage II sporulation protein D
PPHEPGDA_03848 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPHEPGDA_03849 9e-133 ywmB S TATA-box binding
PPHEPGDA_03850 1.3e-32 ywzB S membrane
PPHEPGDA_03851 2.8e-87 ywmA
PPHEPGDA_03852 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PPHEPGDA_03853 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PPHEPGDA_03854 1.9e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PPHEPGDA_03855 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PPHEPGDA_03856 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPHEPGDA_03857 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PPHEPGDA_03858 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PPHEPGDA_03859 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
PPHEPGDA_03860 2.5e-62 atpI S ATP synthase
PPHEPGDA_03861 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PPHEPGDA_03862 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PPHEPGDA_03863 1.6e-94 ywlG S Belongs to the UPF0340 family
PPHEPGDA_03864 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
PPHEPGDA_03865 4e-75 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PPHEPGDA_03866 4.9e-91 mntP P Probably functions as a manganese efflux pump
PPHEPGDA_03867 2e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PPHEPGDA_03868 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
PPHEPGDA_03869 6.1e-112 spoIIR S stage II sporulation protein R
PPHEPGDA_03870 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
PPHEPGDA_03872 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PPHEPGDA_03873 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PPHEPGDA_03874 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_03875 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
PPHEPGDA_03876 8.6e-160 ywkB S Membrane transport protein
PPHEPGDA_03877 0.0 sfcA 1.1.1.38 C malic enzyme
PPHEPGDA_03878 7e-104 tdk 2.7.1.21 F thymidine kinase
PPHEPGDA_03879 1.1e-32 rpmE J Binds the 23S rRNA
PPHEPGDA_03880 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PPHEPGDA_03881 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
PPHEPGDA_03882 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PPHEPGDA_03883 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PPHEPGDA_03884 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
PPHEPGDA_03885 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
PPHEPGDA_03886 1.8e-90 ywjG S Domain of unknown function (DUF2529)
PPHEPGDA_03887 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PPHEPGDA_03888 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PPHEPGDA_03889 2.8e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
PPHEPGDA_03890 0.0 fadF C COG0247 Fe-S oxidoreductase
PPHEPGDA_03891 1.9e-212 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
PPHEPGDA_03892 8e-182 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
PPHEPGDA_03893 3.5e-42 ywjC
PPHEPGDA_03894 2.6e-94 ywjB H RibD C-terminal domain
PPHEPGDA_03895 0.0 ywjA V ABC transporter
PPHEPGDA_03896 2.1e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PPHEPGDA_03897 9.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
PPHEPGDA_03898 3.6e-94 narJ 1.7.5.1 C nitrate reductase
PPHEPGDA_03899 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
PPHEPGDA_03900 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PPHEPGDA_03901 7e-86 arfM T cyclic nucleotide binding
PPHEPGDA_03902 1.7e-139 ywiC S YwiC-like protein
PPHEPGDA_03903 2.6e-129 fnr K helix_turn_helix, cAMP Regulatory protein
PPHEPGDA_03904 1e-213 narK P COG2223 Nitrate nitrite transporter
PPHEPGDA_03905 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PPHEPGDA_03906 4.7e-73 ywiB S protein conserved in bacteria
PPHEPGDA_03907 1e-07 S Bacteriocin subtilosin A
PPHEPGDA_03908 1.3e-270 C Fe-S oxidoreductases
PPHEPGDA_03910 3.3e-132 cbiO V ABC transporter
PPHEPGDA_03911 8e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
PPHEPGDA_03912 1.2e-214 2.7.1.26, 2.7.7.2 L Peptidase, M16
PPHEPGDA_03913 8e-246 L Peptidase, M16
PPHEPGDA_03915 6.2e-244 ywhL CO amine dehydrogenase activity
PPHEPGDA_03916 3e-190 ywhK CO amine dehydrogenase activity
PPHEPGDA_03917 4.4e-78 S aspartate phosphatase
PPHEPGDA_03919 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
PPHEPGDA_03920 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
PPHEPGDA_03921 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
PPHEPGDA_03922 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PPHEPGDA_03923 1.4e-48
PPHEPGDA_03924 5.2e-95 ywhD S YwhD family
PPHEPGDA_03925 3.3e-118 ywhC S Peptidase family M50
PPHEPGDA_03926 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
PPHEPGDA_03927 9.5e-71 ywhA K Transcriptional regulator
PPHEPGDA_03928 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PPHEPGDA_03930 2.8e-236 mmr U Major Facilitator Superfamily
PPHEPGDA_03931 6.2e-79 yffB K Transcriptional regulator
PPHEPGDA_03932 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
PPHEPGDA_03933 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
PPHEPGDA_03934 3.1e-36 ywzC S Belongs to the UPF0741 family
PPHEPGDA_03935 2.1e-108 rsfA_1
PPHEPGDA_03936 4.5e-155 ywfM EG EamA-like transporter family
PPHEPGDA_03937 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
PPHEPGDA_03938 1.1e-156 cysL K Transcriptional regulator
PPHEPGDA_03939 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
PPHEPGDA_03940 3.3e-146 ywfI C May function as heme-dependent peroxidase
PPHEPGDA_03941 1e-95 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_03942 1.1e-11 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_03943 1.9e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
PPHEPGDA_03944 1.9e-209 bacE EGP Major facilitator Superfamily
PPHEPGDA_03945 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
PPHEPGDA_03946 1.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_03947 1.2e-120 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
PPHEPGDA_03948 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
PPHEPGDA_03949 1.3e-203 ywfA EGP Major facilitator Superfamily
PPHEPGDA_03950 5.7e-261 lysP E amino acid
PPHEPGDA_03951 0.0 rocB E arginine degradation protein
PPHEPGDA_03952 4.6e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
PPHEPGDA_03953 3.1e-242 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
PPHEPGDA_03954 1.2e-77
PPHEPGDA_03955 1.3e-86 spsL 5.1.3.13 M Spore Coat
PPHEPGDA_03956 6.5e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PPHEPGDA_03957 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PPHEPGDA_03958 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PPHEPGDA_03959 1.4e-184 spsG M Spore Coat
PPHEPGDA_03960 3.8e-128 spsF M Spore Coat
PPHEPGDA_03961 2.1e-213 spsE 2.5.1.56 M acid synthase
PPHEPGDA_03962 3.7e-162 spsD 2.3.1.210 K Spore Coat
PPHEPGDA_03963 1.6e-221 spsC E Belongs to the DegT DnrJ EryC1 family
PPHEPGDA_03964 1.4e-267 spsB M Capsule polysaccharide biosynthesis protein
PPHEPGDA_03965 1.8e-144 spsA M Spore Coat
PPHEPGDA_03966 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
PPHEPGDA_03967 9.7e-59 ywdK S small membrane protein
PPHEPGDA_03968 2.4e-237 ywdJ F Xanthine uracil
PPHEPGDA_03969 5e-48 ywdI S Family of unknown function (DUF5327)
PPHEPGDA_03970 2.9e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PPHEPGDA_03971 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PPHEPGDA_03972 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
PPHEPGDA_03974 1.3e-111 ywdD
PPHEPGDA_03975 1.3e-57 pex K Transcriptional regulator PadR-like family
PPHEPGDA_03976 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PPHEPGDA_03977 2e-28 ywdA
PPHEPGDA_03978 1.1e-286 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
PPHEPGDA_03979 4.7e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_03980 2.6e-138 focA P Formate/nitrite transporter
PPHEPGDA_03981 7e-150 sacT K transcriptional antiterminator
PPHEPGDA_03983 0.0 vpr O Belongs to the peptidase S8 family
PPHEPGDA_03984 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPHEPGDA_03985 6.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
PPHEPGDA_03986 8.3e-201 L COG3666 Transposase and inactivated derivatives
PPHEPGDA_03987 1.5e-137 rodA D Belongs to the SEDS family
PPHEPGDA_03989 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
PPHEPGDA_03990 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PPHEPGDA_03991 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
PPHEPGDA_03992 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PPHEPGDA_03993 3.5e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
PPHEPGDA_03994 1e-35 ywzA S membrane
PPHEPGDA_03995 2.1e-301 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PPHEPGDA_03996 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PPHEPGDA_03997 9.5e-60 gtcA S GtrA-like protein
PPHEPGDA_03998 2.3e-119 ywcC K transcriptional regulator
PPHEPGDA_04000 6.4e-48 ywcB S Protein of unknown function, DUF485
PPHEPGDA_04001 3.1e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PPHEPGDA_04002 6.1e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
PPHEPGDA_04003 4.9e-224 ywbN P Dyp-type peroxidase family protein
PPHEPGDA_04004 1.6e-184 ycdO P periplasmic lipoprotein involved in iron transport
PPHEPGDA_04005 3.1e-246 P COG0672 High-affinity Fe2 Pb2 permease
PPHEPGDA_04006 2.9e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PPHEPGDA_04007 5.3e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PPHEPGDA_04008 8.1e-152 ywbI K Transcriptional regulator
PPHEPGDA_04009 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
PPHEPGDA_04010 2.3e-111 ywbG M effector of murein hydrolase
PPHEPGDA_04011 9e-207 ywbF EGP Major facilitator Superfamily
PPHEPGDA_04012 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
PPHEPGDA_04013 1e-218 ywbD 2.1.1.191 J Methyltransferase
PPHEPGDA_04014 9.9e-67 ywbC 4.4.1.5 E glyoxalase
PPHEPGDA_04015 2e-126 ywbB S Protein of unknown function (DUF2711)
PPHEPGDA_04016 1.7e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPHEPGDA_04017 3.7e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
PPHEPGDA_04018 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PPHEPGDA_04019 1.2e-152 sacY K transcriptional antiterminator
PPHEPGDA_04020 4.5e-168 gspA M General stress
PPHEPGDA_04021 3.7e-123 ywaF S Integral membrane protein
PPHEPGDA_04022 2.3e-87 ywaE K Transcriptional regulator
PPHEPGDA_04023 7e-231 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PPHEPGDA_04024 5.7e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
PPHEPGDA_04025 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
PPHEPGDA_04026 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PPHEPGDA_04027 5e-14 S D-Ala-teichoic acid biosynthesis protein
PPHEPGDA_04028 6.3e-290 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_04029 1.2e-232 dltB M membrane protein involved in D-alanine export
PPHEPGDA_04030 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PPHEPGDA_04031 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PPHEPGDA_04032 8.6e-47 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_04033 2.7e-64 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_04034 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PPHEPGDA_04035 2.4e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
PPHEPGDA_04036 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
PPHEPGDA_04037 8.2e-249 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PPHEPGDA_04038 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
PPHEPGDA_04039 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
PPHEPGDA_04040 9.3e-19 yxzF
PPHEPGDA_04041 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PPHEPGDA_04042 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
PPHEPGDA_04043 4.5e-214 yxlH EGP Major facilitator Superfamily
PPHEPGDA_04044 1.3e-137 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
PPHEPGDA_04045 9.7e-166 yxlF V ABC transporter, ATP-binding protein
PPHEPGDA_04046 1e-27 yxlE S Phospholipase_D-nuclease N-terminal
PPHEPGDA_04047 2.2e-28
PPHEPGDA_04048 5.6e-47 yxlC S Family of unknown function (DUF5345)
PPHEPGDA_04049 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
PPHEPGDA_04050 1.5e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
PPHEPGDA_04051 2.5e-67 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PPHEPGDA_04052 1.4e-48 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PPHEPGDA_04053 0.0 cydD V ATP-binding protein
PPHEPGDA_04054 3.5e-310 cydD V ATP-binding
PPHEPGDA_04055 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
PPHEPGDA_04056 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
PPHEPGDA_04057 2.1e-228 cimH C COG3493 Na citrate symporter
PPHEPGDA_04058 4.7e-311 3.4.24.84 O Peptidase family M48
PPHEPGDA_04060 1.6e-154 yxkH G Polysaccharide deacetylase
PPHEPGDA_04061 5.9e-205 msmK P Belongs to the ABC transporter superfamily
PPHEPGDA_04062 2e-163 lrp QT PucR C-terminal helix-turn-helix domain
PPHEPGDA_04063 5.3e-151 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_04064 9e-107 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_04065 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PPHEPGDA_04066 2.3e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PPHEPGDA_04067 5.9e-77 S Protein of unknown function (DUF1453)
PPHEPGDA_04068 1e-178 yxjM T Signal transduction histidine kinase
PPHEPGDA_04069 3.7e-114 K helix_turn_helix, Lux Regulon
PPHEPGDA_04070 3.4e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PPHEPGDA_04072 1.4e-86 yxjI S LURP-one-related
PPHEPGDA_04073 7.9e-221 yxjG 2.1.1.14 E Methionine synthase
PPHEPGDA_04074 1.1e-217 yxjG 2.1.1.14 E Methionine synthase
PPHEPGDA_04075 3.7e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
PPHEPGDA_04076 1.7e-114 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
PPHEPGDA_04077 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PPHEPGDA_04078 2.9e-252 yxjC EG COG2610 H gluconate symporter and related permeases
PPHEPGDA_04079 7.1e-158 rlmA 2.1.1.187 Q Methyltransferase domain
PPHEPGDA_04080 2.1e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PPHEPGDA_04081 8.3e-103 T Domain of unknown function (DUF4163)
PPHEPGDA_04082 3e-47 yxiS
PPHEPGDA_04083 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
PPHEPGDA_04084 6.6e-224 citH C Citrate transporter
PPHEPGDA_04085 3.3e-143 exoK GH16 M licheninase activity
PPHEPGDA_04086 3.1e-150 licT K transcriptional antiterminator
PPHEPGDA_04087 4.7e-112
PPHEPGDA_04088 5.2e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
PPHEPGDA_04089 2.8e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
PPHEPGDA_04090 2.5e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
PPHEPGDA_04093 1.3e-42 yxiJ S YxiJ-like protein
PPHEPGDA_04096 1.2e-34
PPHEPGDA_04097 1.1e-83 yxiI S Protein of unknown function (DUF2716)
PPHEPGDA_04098 1.5e-136
PPHEPGDA_04099 8.3e-13 yxiG
PPHEPGDA_04100 5.3e-16 yxiG
PPHEPGDA_04101 1.9e-38 S Protein of unknown function (DUF2750)
PPHEPGDA_04102 3.4e-52 yxxG
PPHEPGDA_04103 4.3e-68 yxiG
PPHEPGDA_04104 4.1e-44
PPHEPGDA_04105 4.9e-76
PPHEPGDA_04106 4.7e-94 S Protein of unknown function (DUF4240)
PPHEPGDA_04107 4.1e-142
PPHEPGDA_04109 7e-55
PPHEPGDA_04110 6.1e-80 wapA M COG3209 Rhs family protein
PPHEPGDA_04111 4.1e-14 yxiJ S YxiJ-like protein
PPHEPGDA_04112 0.0 wapA M COG3209 Rhs family protein
PPHEPGDA_04113 1.3e-163 yxxF EG EamA-like transporter family
PPHEPGDA_04114 2.8e-54 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_04115 4e-34 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
PPHEPGDA_04116 2.3e-120 1.14.11.45 E 2OG-Fe dioxygenase
PPHEPGDA_04117 1.1e-72 yxiE T Belongs to the universal stress protein A family
PPHEPGDA_04118 6.8e-253 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPHEPGDA_04119 2.9e-40
PPHEPGDA_04120 1.1e-77 S SMI1 / KNR4 family
PPHEPGDA_04121 3.1e-273 S nuclease activity
PPHEPGDA_04122 4.1e-21 S Immunity protein 8
PPHEPGDA_04123 1.9e-212 S nuclease activity
PPHEPGDA_04124 1.4e-38 yxiC S Family of unknown function (DUF5344)
PPHEPGDA_04125 2.3e-20 S Domain of unknown function (DUF5082)
PPHEPGDA_04126 2.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
PPHEPGDA_04127 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
PPHEPGDA_04128 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
PPHEPGDA_04129 4.3e-182 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PPHEPGDA_04130 2e-78 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
PPHEPGDA_04131 1.5e-161 lysP E amino acid
PPHEPGDA_04132 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
PPHEPGDA_04133 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PPHEPGDA_04134 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PPHEPGDA_04135 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
PPHEPGDA_04136 1.4e-150 yxxB S Domain of Unknown Function (DUF1206)
PPHEPGDA_04137 1.6e-197 eutH E Ethanolamine utilisation protein, EutH
PPHEPGDA_04138 2.8e-249 yxeQ S MmgE/PrpD family
PPHEPGDA_04139 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
PPHEPGDA_04140 2.9e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
PPHEPGDA_04141 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
PPHEPGDA_04142 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
PPHEPGDA_04143 2.6e-91 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PPHEPGDA_04144 1.6e-252 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PPHEPGDA_04145 1.2e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PPHEPGDA_04146 8.9e-150 yidA S hydrolases of the HAD superfamily
PPHEPGDA_04149 4.3e-19 yxeE
PPHEPGDA_04150 5.6e-16 yxeD
PPHEPGDA_04151 7.2e-68
PPHEPGDA_04152 2.3e-176 fhuD P ABC transporter
PPHEPGDA_04153 3.4e-58 yxeA S Protein of unknown function (DUF1093)
PPHEPGDA_04154 0.0 yxdM V ABC transporter (permease)
PPHEPGDA_04155 3.7e-137 yxdL V ABC transporter, ATP-binding protein
PPHEPGDA_04156 4.2e-178 T PhoQ Sensor
PPHEPGDA_04157 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_04158 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
PPHEPGDA_04159 2.3e-137 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
PPHEPGDA_04160 3.3e-166 iolH G Xylose isomerase-like TIM barrel
PPHEPGDA_04161 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PPHEPGDA_04162 4e-232 iolF EGP Major facilitator Superfamily
PPHEPGDA_04163 3.6e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PPHEPGDA_04164 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PPHEPGDA_04165 3.2e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PPHEPGDA_04166 9.2e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PPHEPGDA_04167 2.6e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
PPHEPGDA_04168 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
PPHEPGDA_04169 8.3e-176 iolS C Aldo keto reductase
PPHEPGDA_04171 1.9e-47 yxcD S Protein of unknown function (DUF2653)
PPHEPGDA_04172 8.3e-241 csbC EGP Major facilitator Superfamily
PPHEPGDA_04173 0.0 htpG O Molecular chaperone. Has ATPase activity
PPHEPGDA_04175 2.6e-18 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_04176 2.4e-68 IQ Enoyl-(Acyl carrier protein) reductase
PPHEPGDA_04177 3.2e-206 yxbF K Bacterial regulatory proteins, tetR family
PPHEPGDA_04178 7.6e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
PPHEPGDA_04179 8.8e-33 yxaI S membrane protein domain
PPHEPGDA_04180 5.7e-63 S Family of unknown function (DUF5391)
PPHEPGDA_04181 1.5e-74 yxaI S membrane protein domain
PPHEPGDA_04182 1.4e-223 P Protein of unknown function (DUF418)
PPHEPGDA_04183 1.4e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
PPHEPGDA_04184 4.6e-100 yxaF K Transcriptional regulator
PPHEPGDA_04185 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PPHEPGDA_04186 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
PPHEPGDA_04187 5.8e-49 S LrgA family
PPHEPGDA_04188 2.6e-118 yxaC M effector of murein hydrolase
PPHEPGDA_04189 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
PPHEPGDA_04190 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PPHEPGDA_04191 1.2e-126 gntR K transcriptional
PPHEPGDA_04192 3.3e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PPHEPGDA_04193 8.5e-230 gntP EG COG2610 H gluconate symporter and related permeases
PPHEPGDA_04194 2.5e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PPHEPGDA_04195 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
PPHEPGDA_04196 1.8e-284 ahpF O Alkyl hydroperoxide reductase
PPHEPGDA_04197 2.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PPHEPGDA_04198 4.1e-12 bglF G phosphotransferase system
PPHEPGDA_04199 1.1e-124 yydK K Transcriptional regulator
PPHEPGDA_04200 1.7e-12
PPHEPGDA_04201 1.8e-117 S ABC-2 family transporter protein
PPHEPGDA_04202 1.6e-109 prrC P ABC transporter
PPHEPGDA_04203 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
PPHEPGDA_04204 1.7e-37 L COG3385 FOG Transposase and inactivated derivatives
PPHEPGDA_04205 3.2e-77 O Hsp20/alpha crystallin family
PPHEPGDA_04206 8.9e-12 cwlJ 3.5.1.28 M Cell wall
PPHEPGDA_04207 9.9e-119 L PhoH-like protein
PPHEPGDA_04208 1.1e-220 L Transposase
PPHEPGDA_04209 3.2e-37
PPHEPGDA_04210 3.6e-274 V Abi-like protein
PPHEPGDA_04211 9.9e-293 L Superfamily I DNA and RNA helicases
PPHEPGDA_04212 0.0 L AAA ATPase domain
PPHEPGDA_04213 6.6e-116 S HTH-like domain
PPHEPGDA_04214 3.3e-43 S transposition, DNA-mediated
PPHEPGDA_04215 2.4e-11
PPHEPGDA_04216 2.5e-43
PPHEPGDA_04217 2e-137 L COG2801 Transposase and inactivated derivatives
PPHEPGDA_04218 9.1e-50 L Transposase
PPHEPGDA_04219 1.3e-119 L helicase superfamily c-terminal domain
PPHEPGDA_04221 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PPHEPGDA_04222 4.2e-09 S YyzF-like protein
PPHEPGDA_04223 2.2e-67
PPHEPGDA_04224 5.3e-220 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
PPHEPGDA_04226 1.7e-30 yycQ S Protein of unknown function (DUF2651)
PPHEPGDA_04227 1.2e-200 yycP
PPHEPGDA_04228 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
PPHEPGDA_04229 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
PPHEPGDA_04230 1.5e-187 S aspartate phosphatase
PPHEPGDA_04232 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
PPHEPGDA_04233 2.8e-260 rocE E amino acid
PPHEPGDA_04234 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
PPHEPGDA_04235 7.4e-16
PPHEPGDA_04236 2.8e-94
PPHEPGDA_04237 2.3e-24 S Sporulation delaying protein SdpA
PPHEPGDA_04238 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
PPHEPGDA_04239 1.5e-40 sdpR K transcriptional
PPHEPGDA_04240 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
PPHEPGDA_04241 2.7e-219 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PPHEPGDA_04242 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
PPHEPGDA_04243 7.3e-155 yycI S protein conserved in bacteria
PPHEPGDA_04244 4.4e-258 yycH S protein conserved in bacteria
PPHEPGDA_04245 0.0 vicK 2.7.13.3 T Histidine kinase
PPHEPGDA_04246 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PPHEPGDA_04251 3.3e-247 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PPHEPGDA_04252 3.7e-75 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_04253 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PPHEPGDA_04254 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
PPHEPGDA_04256 1.9e-15 yycC K YycC-like protein
PPHEPGDA_04257 8.4e-221 yeaN P COG2807 Cyanate permease
PPHEPGDA_04258 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PPHEPGDA_04259 2.2e-73 rplI J binds to the 23S rRNA
PPHEPGDA_04260 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PPHEPGDA_04261 2e-27 yybS S membrane
PPHEPGDA_04262 3.9e-94 yybS S membrane
PPHEPGDA_04264 4e-14 cotF M Spore coat protein
PPHEPGDA_04265 1.7e-51 cotF M Spore coat protein
PPHEPGDA_04266 1.7e-66 ydeP3 K Transcriptional regulator
PPHEPGDA_04267 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
PPHEPGDA_04268 1.1e-61
PPHEPGDA_04270 4.7e-56 yybO G COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_04271 1.6e-157 yybO G COG0477 Permeases of the major facilitator superfamily
PPHEPGDA_04272 1.8e-95 K TipAS antibiotic-recognition domain
PPHEPGDA_04273 2.4e-123
PPHEPGDA_04274 9.5e-65 yybH S SnoaL-like domain
PPHEPGDA_04275 3.3e-123 yybG S Pentapeptide repeat-containing protein
PPHEPGDA_04276 1.1e-99 ynfM EGP Major facilitator Superfamily
PPHEPGDA_04277 3.5e-67 S Metallo-beta-lactamase superfamily
PPHEPGDA_04278 5.6e-77 yybA 2.3.1.57 K transcriptional
PPHEPGDA_04279 2e-71 yjcF S Acetyltransferase (GNAT) domain
PPHEPGDA_04280 5.5e-96 yyaS S Membrane
PPHEPGDA_04281 1.2e-91 yyaR K Acetyltransferase (GNAT) domain
PPHEPGDA_04282 4.1e-36 yyaQ S YjbR
PPHEPGDA_04283 2.6e-103 yyaP 1.5.1.3 H RibD C-terminal domain
PPHEPGDA_04284 2e-82 yosT L Bacterial transcription activator, effector binding domain
PPHEPGDA_04285 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
PPHEPGDA_04286 8e-168 yyaK S CAAX protease self-immunity
PPHEPGDA_04287 1.8e-243 EGP Major facilitator superfamily
PPHEPGDA_04288 1.7e-91 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
PPHEPGDA_04289 1.9e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PPHEPGDA_04290 1.2e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
PPHEPGDA_04291 3.4e-143 xth 3.1.11.2 L exodeoxyribonuclease III
PPHEPGDA_04292 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PPHEPGDA_04293 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PPHEPGDA_04294 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
PPHEPGDA_04295 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PPHEPGDA_04296 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
PPHEPGDA_04297 2.3e-33 yyzM S protein conserved in bacteria
PPHEPGDA_04298 8.1e-177 yyaD S Membrane
PPHEPGDA_04299 1.6e-111 yyaC S Sporulation protein YyaC
PPHEPGDA_04300 6e-149 spo0J K Belongs to the ParB family
PPHEPGDA_04301 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
PPHEPGDA_04302 3.7e-73 S Bacterial PH domain
PPHEPGDA_04303 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
PPHEPGDA_04304 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
PPHEPGDA_04305 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PPHEPGDA_04306 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PPHEPGDA_04307 6.5e-108 jag S single-stranded nucleic acid binding R3H
PPHEPGDA_04308 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PPHEPGDA_04309 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PPHEPGDA_04310 6.1e-163
PPHEPGDA_04311 1e-152 ydjC S Abhydrolase domain containing 18
PPHEPGDA_04312 2.5e-72 prsK T Histidine kinase-like ATPases
PPHEPGDA_04313 9.7e-42 T cheY-homologous receiver domain
PPHEPGDA_04314 9.9e-37 K Transcriptional
PPHEPGDA_04315 5.9e-23 S Family of unknown function
PPHEPGDA_04318 1.7e-185 M domain protein
PPHEPGDA_04321 8.4e-10
PPHEPGDA_04322 5.8e-129 virB11 2.1.1.37 NU Type II/IV secretion system protein
PPHEPGDA_04323 6.1e-93
PPHEPGDA_04324 2.5e-87
PPHEPGDA_04325 1.6e-13
PPHEPGDA_04330 1.6e-20 S Cag pathogenicity island, type IV secretory system
PPHEPGDA_04331 8.5e-37
PPHEPGDA_04332 6.6e-62
PPHEPGDA_04333 7.1e-241 traE U Psort location Cytoplasmic, score
PPHEPGDA_04334 3.4e-104 polC 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 S WXG100 protein secretion system (Wss), protein YukC
PPHEPGDA_04335 2e-125 yddH CBM50 M Lysozyme-like
PPHEPGDA_04336 5.8e-34
PPHEPGDA_04337 3.5e-28
PPHEPGDA_04338 1.2e-211 traK U TraM recognition site of TraD and TraG
PPHEPGDA_04339 1.3e-101
PPHEPGDA_04340 1.2e-21
PPHEPGDA_04341 5.1e-97 L Protein of unknown function (DUF3991)
PPHEPGDA_04342 1.9e-228 topB 5.99.1.2 L DNA topoisomerase III
PPHEPGDA_04343 1.1e-37 V Restriction endonuclease
PPHEPGDA_04347 2.9e-116 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
PPHEPGDA_04349 2.4e-14
PPHEPGDA_04358 7.3e-100 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
PPHEPGDA_04369 7.3e-100 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
PPHEPGDA_04374 4.6e-08 S Protein of unknown function (DUF2786)
PPHEPGDA_04375 2.9e-08 S Protein of unknown function (DUF2786)
PPHEPGDA_04377 1.1e-26
PPHEPGDA_04378 4.3e-62 I PLD-like domain
PPHEPGDA_04379 7.4e-11
PPHEPGDA_04380 9e-14
PPHEPGDA_04381 4.9e-145 pcrA1 3.6.4.12 L UvrD-like helicase C-terminal domain
PPHEPGDA_04382 2.5e-199 L AAA ATPase domain
PPHEPGDA_04383 3.1e-08 L Belongs to the 'phage' integrase family
PPHEPGDA_04384 2.8e-12 K Cro/C1-type HTH DNA-binding domain
PPHEPGDA_04385 1.8e-24 L Protein involved in DNA binding, DNA transposition and DNA integration
PPHEPGDA_04388 6.9e-234 S impB/mucB/samB family C-terminal domain
PPHEPGDA_04389 6e-52 S YolD-like protein
PPHEPGDA_04397 2.4e-69 L integrase family
PPHEPGDA_04402 8.8e-36
PPHEPGDA_04404 7.9e-46 S Conserved Protein
PPHEPGDA_04412 1.2e-83 S Protein of unknown function DUF262
PPHEPGDA_04413 4.8e-09
PPHEPGDA_04415 5.1e-08
PPHEPGDA_04417 5.8e-131 L Psort location Cytoplasmic, score
PPHEPGDA_04418 3.4e-201 S MobA/MobL family
PPHEPGDA_04419 1.7e-08
PPHEPGDA_04420 2.5e-13
PPHEPGDA_04421 3.8e-58 fic D Fic/DOC family
PPHEPGDA_04424 3e-106

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)