ORF_ID e_value Gene_name EC_number CAZy COGs Description
MFLELIEK_00001 1.3e-235 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MFLELIEK_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MFLELIEK_00003 2.4e-33 yaaA S S4 domain
MFLELIEK_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MFLELIEK_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
MFLELIEK_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFLELIEK_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MFLELIEK_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00011 2.6e-180 yaaC S YaaC-like Protein
MFLELIEK_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
MFLELIEK_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MFLELIEK_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
MFLELIEK_00015 6.8e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
MFLELIEK_00016 8.9e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MFLELIEK_00017 1.3e-09
MFLELIEK_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
MFLELIEK_00019 7.9e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
MFLELIEK_00020 2e-212 yaaH M Glycoside Hydrolase Family
MFLELIEK_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
MFLELIEK_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MFLELIEK_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFLELIEK_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MFLELIEK_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MFLELIEK_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
MFLELIEK_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
MFLELIEK_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
MFLELIEK_00032 1.7e-100 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MFLELIEK_00033 8.4e-202 yaaN P Belongs to the TelA family
MFLELIEK_00034 2.7e-274 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
MFLELIEK_00035 1.4e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MFLELIEK_00036 2.2e-54 yaaQ S protein conserved in bacteria
MFLELIEK_00037 1.5e-71 yaaR S protein conserved in bacteria
MFLELIEK_00038 2.4e-181 holB 2.7.7.7 L DNA polymerase III
MFLELIEK_00039 6.1e-146 yaaT S stage 0 sporulation protein
MFLELIEK_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
MFLELIEK_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
MFLELIEK_00042 3.3e-49 yazA L endonuclease containing a URI domain
MFLELIEK_00043 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MFLELIEK_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
MFLELIEK_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MFLELIEK_00046 1.2e-143 tatD L hydrolase, TatD
MFLELIEK_00047 2e-167 rpfB GH23 T protein conserved in bacteria
MFLELIEK_00048 4.6e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MFLELIEK_00049 1.2e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MFLELIEK_00050 1.6e-136 yabG S peptidase
MFLELIEK_00051 7.8e-39 veg S protein conserved in bacteria
MFLELIEK_00052 8.3e-27 sspF S DNA topological change
MFLELIEK_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MFLELIEK_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MFLELIEK_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
MFLELIEK_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
MFLELIEK_00057 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MFLELIEK_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MFLELIEK_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MFLELIEK_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MFLELIEK_00061 2.4e-39 yabK S Peptide ABC transporter permease
MFLELIEK_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MFLELIEK_00063 1.5e-92 spoVT K stage V sporulation protein
MFLELIEK_00064 2.3e-282 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_00065 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
MFLELIEK_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
MFLELIEK_00067 1.5e-49 yabP S Sporulation protein YabP
MFLELIEK_00068 9.5e-107 yabQ S spore cortex biosynthesis protein
MFLELIEK_00069 1.1e-44 divIC D Septum formation initiator
MFLELIEK_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
MFLELIEK_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
MFLELIEK_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
MFLELIEK_00075 1.8e-184 KLT serine threonine protein kinase
MFLELIEK_00076 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MFLELIEK_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MFLELIEK_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MFLELIEK_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MFLELIEK_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MFLELIEK_00081 6.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
MFLELIEK_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFLELIEK_00083 2.2e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFLELIEK_00084 7.3e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
MFLELIEK_00085 2.3e-167 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
MFLELIEK_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MFLELIEK_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MFLELIEK_00088 1.8e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MFLELIEK_00089 4.1e-30 yazB K transcriptional
MFLELIEK_00090 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFLELIEK_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MFLELIEK_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00097 2e-08
MFLELIEK_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00103 2.9e-76 ctsR K Belongs to the CtsR family
MFLELIEK_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
MFLELIEK_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
MFLELIEK_00106 0.0 clpC O Belongs to the ClpA ClpB family
MFLELIEK_00107 2.1e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MFLELIEK_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
MFLELIEK_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
MFLELIEK_00110 4.2e-124 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
MFLELIEK_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
MFLELIEK_00112 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MFLELIEK_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
MFLELIEK_00114 3.2e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFLELIEK_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MFLELIEK_00116 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFLELIEK_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
MFLELIEK_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
MFLELIEK_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MFLELIEK_00120 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
MFLELIEK_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MFLELIEK_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MFLELIEK_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MFLELIEK_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MFLELIEK_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
MFLELIEK_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLELIEK_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLELIEK_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
MFLELIEK_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MFLELIEK_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MFLELIEK_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MFLELIEK_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MFLELIEK_00133 1.7e-179 ybaC 3.4.11.5 S Alpha/beta hydrolase family
MFLELIEK_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MFLELIEK_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MFLELIEK_00136 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
MFLELIEK_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MFLELIEK_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MFLELIEK_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MFLELIEK_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MFLELIEK_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MFLELIEK_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MFLELIEK_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
MFLELIEK_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MFLELIEK_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MFLELIEK_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MFLELIEK_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MFLELIEK_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFLELIEK_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MFLELIEK_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MFLELIEK_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MFLELIEK_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MFLELIEK_00153 1.9e-23 rpmD J Ribosomal protein L30
MFLELIEK_00154 1.8e-72 rplO J binds to the 23S rRNA
MFLELIEK_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MFLELIEK_00156 4.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MFLELIEK_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
MFLELIEK_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MFLELIEK_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MFLELIEK_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MFLELIEK_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MFLELIEK_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MFLELIEK_00163 3.6e-58 rplQ J Ribosomal protein L17
MFLELIEK_00164 2.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLELIEK_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLELIEK_00166 4e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MFLELIEK_00167 6.3e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MFLELIEK_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MFLELIEK_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
MFLELIEK_00170 3.4e-143 ybaJ Q Methyltransferase domain
MFLELIEK_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
MFLELIEK_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
MFLELIEK_00174 1.2e-84 gerD
MFLELIEK_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
MFLELIEK_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
MFLELIEK_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00180 2e-08
MFLELIEK_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00186 1.3e-249 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
MFLELIEK_00188 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
MFLELIEK_00189 3.3e-138 ybbA S Putative esterase
MFLELIEK_00190 8.7e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00191 1.8e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00192 3e-165 feuA P Iron-uptake system-binding protein
MFLELIEK_00193 1.2e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
MFLELIEK_00194 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
MFLELIEK_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
MFLELIEK_00196 4.1e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
MFLELIEK_00197 2.2e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_00198 1.4e-150 ybbH K transcriptional
MFLELIEK_00199 8.8e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MFLELIEK_00200 1.9e-86 ybbJ J acetyltransferase
MFLELIEK_00201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
MFLELIEK_00207 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_00208 1.8e-102 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
MFLELIEK_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFLELIEK_00210 1.5e-224 ybbR S protein conserved in bacteria
MFLELIEK_00211 3.5e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MFLELIEK_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MFLELIEK_00213 6e-171 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFLELIEK_00214 9.9e-120 adaA 3.2.2.21 K Transcriptional regulator
MFLELIEK_00215 2e-97 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFLELIEK_00216 1.1e-270 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFLELIEK_00217 0.0 ybcC S Belongs to the UPF0753 family
MFLELIEK_00218 6.5e-93 can 4.2.1.1 P carbonic anhydrase
MFLELIEK_00219 3.9e-47
MFLELIEK_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
MFLELIEK_00221 5.1e-50 ybzH K Helix-turn-helix domain
MFLELIEK_00222 1.2e-200 ybcL EGP Major facilitator Superfamily
MFLELIEK_00223 2.5e-56
MFLELIEK_00224 1.4e-181 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFLELIEK_00225 3.8e-122 T Transcriptional regulatory protein, C terminal
MFLELIEK_00226 1.8e-168 T His Kinase A (phospho-acceptor) domain
MFLELIEK_00228 3.9e-139 KLT Protein tyrosine kinase
MFLELIEK_00229 8.5e-151 ybdN
MFLELIEK_00230 1.5e-214 ybdO S Domain of unknown function (DUF4885)
MFLELIEK_00231 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_00232 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
MFLELIEK_00233 4.9e-30 ybxH S Family of unknown function (DUF5370)
MFLELIEK_00234 1.8e-150 ybxI 3.5.2.6 V beta-lactamase
MFLELIEK_00235 7.6e-241 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
MFLELIEK_00236 4.9e-41 ybyB
MFLELIEK_00237 8.8e-290 ybeC E amino acid
MFLELIEK_00238 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFLELIEK_00239 7.3e-258 glpT G -transporter
MFLELIEK_00240 2.9e-35 S Protein of unknown function (DUF2651)
MFLELIEK_00241 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
MFLELIEK_00242 3.2e-223 ybfB G COG0477 Permeases of the major facilitator superfamily
MFLELIEK_00243 3.3e-161 ybfH EG EamA-like transporter family
MFLELIEK_00244 2.3e-145 msmR K AraC-like ligand binding domain
MFLELIEK_00245 7.4e-31 K sigma factor activity
MFLELIEK_00246 9e-21 xhlB S SPP1 phage holin
MFLELIEK_00247 2e-164 2.7.1.50, 3.5.2.6 GH19 M Lysin motif
MFLELIEK_00248 3.9e-57
MFLELIEK_00249 2.2e-210 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MFLELIEK_00250 2.9e-176 mpr 3.4.21.19 M Belongs to the peptidase S1B family
MFLELIEK_00252 1.8e-167 S Alpha/beta hydrolase family
MFLELIEK_00253 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFLELIEK_00254 2.7e-85 ybfM S SNARE associated Golgi protein
MFLELIEK_00255 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
MFLELIEK_00256 4.6e-45 ybfN
MFLELIEK_00257 3.4e-255 S Erythromycin esterase
MFLELIEK_00258 6.7e-167 ybfP K Transcriptional regulator
MFLELIEK_00259 3.9e-192 yceA S Belongs to the UPF0176 family
MFLELIEK_00260 6.4e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFLELIEK_00261 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_00262 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFLELIEK_00263 4.9e-128 K UTRA
MFLELIEK_00265 4.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MFLELIEK_00266 2e-261 mmuP E amino acid
MFLELIEK_00267 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
MFLELIEK_00268 2.3e-257 agcS E Sodium alanine symporter
MFLELIEK_00269 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
MFLELIEK_00270 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
MFLELIEK_00271 9e-170 glnL T Regulator
MFLELIEK_00272 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
MFLELIEK_00273 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFLELIEK_00274 1.6e-255 gudP G COG0477 Permeases of the major facilitator superfamily
MFLELIEK_00275 3.6e-268 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFLELIEK_00276 2.1e-123 ycbG K FCD
MFLELIEK_00277 7e-297 garD 4.2.1.42, 4.2.1.7 G Altronate
MFLELIEK_00278 4.8e-176 ycbJ S Macrolide 2'-phosphotransferase
MFLELIEK_00279 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
MFLELIEK_00280 7.3e-172 eamA1 EG spore germination
MFLELIEK_00281 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_00282 2.4e-170 T PhoQ Sensor
MFLELIEK_00283 4.8e-168 ycbN V ABC transporter, ATP-binding protein
MFLELIEK_00284 3e-114 S ABC-2 family transporter protein
MFLELIEK_00285 8.2e-53 ycbP S Protein of unknown function (DUF2512)
MFLELIEK_00286 1.3e-78 sleB 3.5.1.28 M Cell wall
MFLELIEK_00287 6.6e-136 ycbR T vWA found in TerF C terminus
MFLELIEK_00288 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
MFLELIEK_00289 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFLELIEK_00290 4.4e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFLELIEK_00291 4.5e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MFLELIEK_00292 5.2e-201 ycbU E Selenocysteine lyase
MFLELIEK_00293 5.8e-229 lmrB EGP the major facilitator superfamily
MFLELIEK_00294 1.6e-100 yxaF K Transcriptional regulator
MFLELIEK_00295 6.9e-201 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
MFLELIEK_00296 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFLELIEK_00297 2e-59 S RDD family
MFLELIEK_00298 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
MFLELIEK_00299 2e-161 2.7.13.3 T GHKL domain
MFLELIEK_00300 1.2e-126 lytR_2 T LytTr DNA-binding domain
MFLELIEK_00301 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
MFLELIEK_00302 4.5e-203 natB CP ABC-2 family transporter protein
MFLELIEK_00303 1.6e-174 yccK C Aldo keto reductase
MFLELIEK_00304 6.6e-177 ycdA S Domain of unknown function (DUF5105)
MFLELIEK_00305 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_00306 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_00307 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
MFLELIEK_00308 1.2e-70 S response regulator aspartate phosphatase
MFLELIEK_00309 3.1e-82 S response regulator aspartate phosphatase
MFLELIEK_00310 4.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_00311 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
MFLELIEK_00312 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
MFLELIEK_00313 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFLELIEK_00314 2.2e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFLELIEK_00315 5.6e-186 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_00316 2.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
MFLELIEK_00317 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
MFLELIEK_00318 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
MFLELIEK_00319 1.4e-136 terC P Protein of unknown function (DUF475)
MFLELIEK_00320 0.0 yceG S Putative component of 'biosynthetic module'
MFLELIEK_00321 2.6e-192 yceH P Belongs to the TelA family
MFLELIEK_00322 8.7e-218 naiP P Uncharacterised MFS-type transporter YbfB
MFLELIEK_00323 3.2e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
MFLELIEK_00324 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
MFLELIEK_00325 5.1e-229 proV 3.6.3.32 E glycine betaine
MFLELIEK_00326 1.3e-127 opuAB P glycine betaine
MFLELIEK_00327 1.5e-163 opuAC E glycine betaine
MFLELIEK_00328 1.4e-217 amhX S amidohydrolase
MFLELIEK_00329 8.7e-257 ycgA S Membrane
MFLELIEK_00330 4.1e-81 ycgB
MFLELIEK_00331 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
MFLELIEK_00332 7.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MFLELIEK_00333 5.2e-290 lctP C L-lactate permease
MFLELIEK_00334 3.6e-261 mdr EGP Major facilitator Superfamily
MFLELIEK_00335 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_00336 6.8e-113 ycgF E Lysine exporter protein LysE YggA
MFLELIEK_00337 2.7e-114 yqcI S YqcI/YcgG family
MFLELIEK_00338 1.6e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_00339 2.4e-112 ycgI S Domain of unknown function (DUF1989)
MFLELIEK_00340 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MFLELIEK_00341 9.5e-109 tmrB S AAA domain
MFLELIEK_00342 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MFLELIEK_00343 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
MFLELIEK_00344 2.2e-179 oxyR3 K LysR substrate binding domain
MFLELIEK_00345 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
MFLELIEK_00346 2.9e-145 ycgL S Predicted nucleotidyltransferase
MFLELIEK_00347 5.1e-170 ycgM E Proline dehydrogenase
MFLELIEK_00348 4.7e-293 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFLELIEK_00349 2.6e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLELIEK_00350 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
MFLELIEK_00351 2.6e-147 ycgQ S membrane
MFLELIEK_00352 1.2e-139 ycgR S permeases
MFLELIEK_00353 5.5e-158 I alpha/beta hydrolase fold
MFLELIEK_00354 3.2e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MFLELIEK_00355 6.4e-276 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MFLELIEK_00356 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
MFLELIEK_00357 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MFLELIEK_00358 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFLELIEK_00359 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
MFLELIEK_00360 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
MFLELIEK_00361 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
MFLELIEK_00362 5.5e-109 yciB M ErfK YbiS YcfS YnhG
MFLELIEK_00363 5.4e-228 yciC S GTPases (G3E family)
MFLELIEK_00364 1.6e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
MFLELIEK_00365 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
MFLELIEK_00367 7.8e-52 yckD S Protein of unknown function (DUF2680)
MFLELIEK_00368 1.6e-38 K MarR family
MFLELIEK_00369 9.3e-24
MFLELIEK_00370 7.8e-121 S AAA domain
MFLELIEK_00371 1.2e-295 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFLELIEK_00372 1.7e-69 nin S Competence protein J (ComJ)
MFLELIEK_00373 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
MFLELIEK_00374 1e-179 tlpC 2.7.13.3 NT chemotaxis protein
MFLELIEK_00375 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
MFLELIEK_00376 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
MFLELIEK_00377 1.3e-63 hxlR K transcriptional
MFLELIEK_00378 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_00379 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_00380 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
MFLELIEK_00381 6.4e-139 srfAD Q thioesterase
MFLELIEK_00382 6.1e-227 EGP Major Facilitator Superfamily
MFLELIEK_00383 4.9e-91 S YcxB-like protein
MFLELIEK_00384 4.5e-161 ycxC EG EamA-like transporter family
MFLELIEK_00385 5.6e-250 ycxD K GntR family transcriptional regulator
MFLELIEK_00386 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MFLELIEK_00387 1.7e-114 yczE S membrane
MFLELIEK_00388 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFLELIEK_00389 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
MFLELIEK_00390 1.3e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MFLELIEK_00391 4.9e-162 bsdA K LysR substrate binding domain
MFLELIEK_00392 3.7e-108 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MFLELIEK_00393 1.2e-282 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
MFLELIEK_00394 4e-39 bsdD 4.1.1.61 S response to toxic substance
MFLELIEK_00395 2.3e-81 yclD
MFLELIEK_00396 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
MFLELIEK_00397 7.3e-267 dtpT E amino acid peptide transporter
MFLELIEK_00398 4.6e-292 yclG M Pectate lyase superfamily protein
MFLELIEK_00400 7.8e-278 gerKA EG Spore germination protein
MFLELIEK_00401 2.7e-227 gerKC S spore germination
MFLELIEK_00402 5.6e-195 gerKB F Spore germination protein
MFLELIEK_00403 5.6e-121 yclH P ABC transporter
MFLELIEK_00404 1.1e-195 yclI V ABC transporter (permease) YclI
MFLELIEK_00405 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_00406 5.2e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MFLELIEK_00407 2e-70 S aspartate phosphatase
MFLELIEK_00410 1.2e-231 lysC 2.7.2.4 E Belongs to the aspartokinase family
MFLELIEK_00411 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00412 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00413 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
MFLELIEK_00414 7.2e-167 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
MFLELIEK_00415 4.9e-75 V Restriction endonuclease
MFLELIEK_00416 3.2e-251 ycnB EGP Major facilitator Superfamily
MFLELIEK_00417 6.5e-154 ycnC K Transcriptional regulator
MFLELIEK_00418 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
MFLELIEK_00419 4.7e-45 ycnE S Monooxygenase
MFLELIEK_00420 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
MFLELIEK_00421 3.9e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_00422 6.3e-246 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFLELIEK_00423 8.4e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFLELIEK_00424 6.1e-149 glcU U Glucose uptake
MFLELIEK_00425 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_00426 2.9e-100 ycnI S protein conserved in bacteria
MFLELIEK_00427 4.2e-308 ycnJ P protein, homolog of Cu resistance protein CopC
MFLELIEK_00428 4.3e-106 ycnK K COG1349 Transcriptional regulators of sugar metabolism
MFLELIEK_00429 7.3e-56
MFLELIEK_00430 1.6e-239 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
MFLELIEK_00431 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
MFLELIEK_00432 4.8e-210 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
MFLELIEK_00433 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
MFLELIEK_00434 5.5e-98 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFLELIEK_00435 1.5e-18 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
MFLELIEK_00436 4.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MFLELIEK_00438 1.2e-135 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
MFLELIEK_00439 5.7e-138 ycsF S Belongs to the UPF0271 (lamB) family
MFLELIEK_00440 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
MFLELIEK_00441 1.1e-147 ycsI S Belongs to the D-glutamate cyclase family
MFLELIEK_00442 2.1e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
MFLELIEK_00443 6.2e-185 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
MFLELIEK_00444 2.7e-132 kipR K Transcriptional regulator
MFLELIEK_00445 2.9e-119 ycsK E anatomical structure formation involved in morphogenesis
MFLELIEK_00447 1.4e-49 yczJ S biosynthesis
MFLELIEK_00448 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
MFLELIEK_00449 2.4e-172 ydhF S Oxidoreductase
MFLELIEK_00450 0.0 mtlR K transcriptional regulator, MtlR
MFLELIEK_00451 2.1e-293 ydaB IQ acyl-CoA ligase
MFLELIEK_00452 9e-99 ydaC Q Methyltransferase domain
MFLELIEK_00453 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_00454 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
MFLELIEK_00455 6.4e-99 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFLELIEK_00456 4.4e-76 ydaG 1.4.3.5 S general stress protein
MFLELIEK_00457 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
MFLELIEK_00458 3.1e-44 ydzA EGP Major facilitator Superfamily
MFLELIEK_00459 2.5e-74 lrpC K Transcriptional regulator
MFLELIEK_00460 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFLELIEK_00461 5.8e-205 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
MFLELIEK_00462 6.5e-151 ydaK T Diguanylate cyclase, GGDEF domain
MFLELIEK_00463 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
MFLELIEK_00464 1.7e-232 ydaM M Glycosyl transferase family group 2
MFLELIEK_00465 0.0 ydaN S Bacterial cellulose synthase subunit
MFLELIEK_00466 0.0 ydaO E amino acid
MFLELIEK_00467 4.7e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
MFLELIEK_00468 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MFLELIEK_00470 1.8e-27
MFLELIEK_00471 1.8e-72 sdpB S Protein conserved in bacteria
MFLELIEK_00473 9.4e-40
MFLELIEK_00474 1.7e-224 mntH P H( )-stimulated, divalent metal cation uptake system
MFLELIEK_00476 4.8e-76 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
MFLELIEK_00477 8.4e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
MFLELIEK_00479 1.2e-55 ydbB G Cupin domain
MFLELIEK_00480 2e-61 ydbC S Domain of unknown function (DUF4937
MFLELIEK_00481 7.9e-154 ydbD P Catalase
MFLELIEK_00482 2.3e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
MFLELIEK_00483 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFLELIEK_00484 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
MFLELIEK_00485 5.3e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFLELIEK_00486 9.7e-181 ydbI S AI-2E family transporter
MFLELIEK_00487 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
MFLELIEK_00488 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFLELIEK_00489 2.7e-52 ydbL
MFLELIEK_00490 1.4e-217 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
MFLELIEK_00491 1.1e-18 S Fur-regulated basic protein B
MFLELIEK_00492 2.2e-07 S Fur-regulated basic protein A
MFLELIEK_00493 9.6e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFLELIEK_00494 4.3e-55 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MFLELIEK_00495 3.9e-201 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MFLELIEK_00496 6.9e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MFLELIEK_00497 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MFLELIEK_00498 2.1e-82 ydbS S Bacterial PH domain
MFLELIEK_00499 3.7e-263 ydbT S Membrane
MFLELIEK_00500 2.2e-105 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
MFLELIEK_00501 2.1e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MFLELIEK_00502 5.5e-182 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
MFLELIEK_00503 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFLELIEK_00504 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
MFLELIEK_00505 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
MFLELIEK_00506 3.7e-143 rsbR T Positive regulator of sigma-B
MFLELIEK_00507 5.2e-57 rsbS T antagonist
MFLELIEK_00508 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
MFLELIEK_00509 9.3e-189 rsbU 3.1.3.3 KT phosphatase
MFLELIEK_00510 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
MFLELIEK_00511 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
MFLELIEK_00512 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_00513 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
MFLELIEK_00514 0.0 yhgF K COG2183 Transcriptional accessory protein
MFLELIEK_00515 8.9e-83 ydcK S Belongs to the SprT family
MFLELIEK_00523 3.2e-114 yecA E amino acid
MFLELIEK_00524 4.6e-107 K Transcriptional regulator
MFLELIEK_00525 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
MFLELIEK_00526 1.6e-43
MFLELIEK_00527 3.3e-138 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFLELIEK_00528 2.7e-13
MFLELIEK_00529 5.6e-34 K Helix-turn-helix XRE-family like proteins
MFLELIEK_00530 1.2e-39
MFLELIEK_00534 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MFLELIEK_00535 8.7e-30 cspL K Cold shock
MFLELIEK_00536 2.3e-78 carD K Transcription factor
MFLELIEK_00537 2.6e-142 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFLELIEK_00538 6.9e-164 rhaS5 K AraC-like ligand binding domain
MFLELIEK_00539 2e-172 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MFLELIEK_00540 6.9e-164 ydeE K AraC family transcriptional regulator
MFLELIEK_00541 2e-258 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_00542 2.1e-217 ydeG EGP Major facilitator superfamily
MFLELIEK_00543 2.7e-45 ydeH
MFLELIEK_00544 2.4e-104 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
MFLELIEK_00545 1.3e-109
MFLELIEK_00546 1.1e-31 S SNARE associated Golgi protein
MFLELIEK_00547 1.8e-14 ptsH G PTS HPr component phosphorylation site
MFLELIEK_00548 3.4e-84 K Transcriptional regulator C-terminal region
MFLELIEK_00549 2e-152 ydeK EG -transporter
MFLELIEK_00550 8.7e-270 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_00551 1.3e-72 maoC I N-terminal half of MaoC dehydratase
MFLELIEK_00552 1.8e-104 ydeN S Serine hydrolase
MFLELIEK_00553 5.7e-55 K HxlR-like helix-turn-helix
MFLELIEK_00554 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MFLELIEK_00555 8.2e-57 arsR K transcriptional
MFLELIEK_00556 1.7e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFLELIEK_00557 9.8e-146 ydfB J GNAT acetyltransferase
MFLELIEK_00558 2.3e-149 ydfC EG EamA-like transporter family
MFLELIEK_00559 7.4e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_00560 8.9e-185 gadB 4.1.1.105, 4.1.1.28, 4.1.1.29 E Pyridoxal-dependent decarboxylase conserved domain
MFLELIEK_00561 1.4e-115 ydfE S Flavin reductase like domain
MFLELIEK_00562 3.9e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
MFLELIEK_00563 1e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFLELIEK_00565 2.7e-176 ydfH 2.7.13.3 T Histidine kinase
MFLELIEK_00566 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_00567 0.0 ydfJ S drug exporters of the RND superfamily
MFLELIEK_00568 2.9e-173 S Alpha/beta hydrolase family
MFLELIEK_00569 7.2e-116 S Protein of unknown function (DUF554)
MFLELIEK_00570 9.2e-147 K Bacterial transcription activator, effector binding domain
MFLELIEK_00571 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFLELIEK_00572 2.1e-111 ydfN C nitroreductase
MFLELIEK_00573 4e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
MFLELIEK_00574 1.2e-62 mhqP S DoxX
MFLELIEK_00575 6.5e-54 traF CO Thioredoxin
MFLELIEK_00576 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
MFLELIEK_00577 6.3e-29
MFLELIEK_00579 2.4e-54 ydfR S Protein of unknown function (DUF421)
MFLELIEK_00580 1.4e-30 ydfR S Protein of unknown function (DUF421)
MFLELIEK_00581 5.8e-121 ydfS S Protein of unknown function (DUF421)
MFLELIEK_00582 1.1e-66 cotP O Belongs to the small heat shock protein (HSP20) family
MFLELIEK_00583 9.8e-36 ydgA S Spore germination protein gerPA/gerPF
MFLELIEK_00584 2.7e-34 ydgB S Spore germination protein gerPA/gerPF
MFLELIEK_00585 4.5e-98 K Bacterial regulatory proteins, tetR family
MFLELIEK_00586 1.6e-52 S DoxX-like family
MFLELIEK_00587 4.6e-82 yycN 2.3.1.128 K Acetyltransferase
MFLELIEK_00588 3.2e-303 expZ S ABC transporter
MFLELIEK_00589 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_00590 4.3e-89 dinB S DinB family
MFLELIEK_00591 2.7e-79 K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_00592 0.0 ydgH S drug exporters of the RND superfamily
MFLELIEK_00593 1e-113 drgA C nitroreductase
MFLELIEK_00594 2.4e-69 ydgJ K Winged helix DNA-binding domain
MFLELIEK_00595 2.2e-208 tcaB EGP Major facilitator Superfamily
MFLELIEK_00596 4.6e-121 ydhB S membrane transporter protein
MFLELIEK_00597 6.5e-122 ydhC K FCD
MFLELIEK_00598 4.8e-243 ydhD M Glycosyl hydrolase
MFLELIEK_00599 1.3e-226 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFLELIEK_00600 5.1e-125
MFLELIEK_00601 2.6e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MFLELIEK_00602 1.1e-65 frataxin S Domain of unknown function (DU1801)
MFLELIEK_00604 1.5e-80 K Acetyltransferase (GNAT) domain
MFLELIEK_00605 1e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MFLELIEK_00606 2.5e-98 ydhK M Protein of unknown function (DUF1541)
MFLELIEK_00607 4.6e-200 pbuE EGP Major facilitator Superfamily
MFLELIEK_00608 4.2e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFLELIEK_00609 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFLELIEK_00610 9.8e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLELIEK_00611 7.3e-285 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFLELIEK_00612 7.4e-132 ydhQ K UTRA
MFLELIEK_00613 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
MFLELIEK_00614 2.5e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
MFLELIEK_00615 9e-214 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
MFLELIEK_00616 6.1e-157 ydhU P Catalase
MFLELIEK_00619 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00620 7.8e-08
MFLELIEK_00622 6.3e-174 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MFLELIEK_00623 5.9e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
MFLELIEK_00624 7.1e-124 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
MFLELIEK_00625 1.1e-83 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MFLELIEK_00626 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MFLELIEK_00627 0.0 ydiF S ABC transporter
MFLELIEK_00628 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
MFLELIEK_00629 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MFLELIEK_00630 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
MFLELIEK_00631 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MFLELIEK_00632 2.9e-27 ydiK S Domain of unknown function (DUF4305)
MFLELIEK_00633 7.9e-129 ydiL S CAAX protease self-immunity
MFLELIEK_00634 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MFLELIEK_00635 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MFLELIEK_00636 2.8e-153 ydjC S Abhydrolase domain containing 18
MFLELIEK_00637 0.0 K NB-ARC domain
MFLELIEK_00638 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
MFLELIEK_00639 7.1e-256 gutA G MFS/sugar transport protein
MFLELIEK_00640 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
MFLELIEK_00641 8.7e-114 pspA KT Phage shock protein A
MFLELIEK_00642 2.8e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFLELIEK_00643 4.5e-135 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
MFLELIEK_00644 5.9e-148 ydjI S virion core protein (lumpy skin disease virus)
MFLELIEK_00645 3.2e-157 S Ion transport 2 domain protein
MFLELIEK_00646 2.9e-257 iolT EGP Major facilitator Superfamily
MFLELIEK_00647 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
MFLELIEK_00648 4.5e-64 ydjM M Lytic transglycolase
MFLELIEK_00649 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
MFLELIEK_00651 1.4e-34 ydjO S Cold-inducible protein YdjO
MFLELIEK_00652 8.4e-156 ydjP I Alpha/beta hydrolase family
MFLELIEK_00653 7.5e-175 yeaA S Protein of unknown function (DUF4003)
MFLELIEK_00654 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
MFLELIEK_00655 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_00656 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MFLELIEK_00657 1.5e-175 yeaC S COG0714 MoxR-like ATPases
MFLELIEK_00658 8.9e-223 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
MFLELIEK_00659 0.0 yebA E COG1305 Transglutaminase-like enzymes
MFLELIEK_00660 8.3e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MFLELIEK_00661 2e-89 K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_00662 9.8e-256 S Domain of unknown function (DUF4179)
MFLELIEK_00663 7.8e-212 pbuG S permease
MFLELIEK_00664 8.3e-116 yebC M Membrane
MFLELIEK_00666 8.9e-93 yebE S UPF0316 protein
MFLELIEK_00667 8e-28 yebG S NETI protein
MFLELIEK_00668 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MFLELIEK_00669 1.3e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MFLELIEK_00670 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MFLELIEK_00671 8.3e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MFLELIEK_00672 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLELIEK_00673 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLELIEK_00674 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MFLELIEK_00675 4.7e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MFLELIEK_00676 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MFLELIEK_00677 3.7e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MFLELIEK_00678 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MFLELIEK_00679 1.1e-234 purD 6.3.4.13 F Belongs to the GARS family
MFLELIEK_00680 1.1e-71 K helix_turn_helix ASNC type
MFLELIEK_00681 1.4e-229 yjeH E Amino acid permease
MFLELIEK_00682 2.7e-27 S Protein of unknown function (DUF2892)
MFLELIEK_00683 0.0 yerA 3.5.4.2 F adenine deaminase
MFLELIEK_00684 6.3e-190 yerB S Protein of unknown function (DUF3048) C-terminal domain
MFLELIEK_00685 4.8e-51 yerC S protein conserved in bacteria
MFLELIEK_00686 2.2e-301 yerD 1.4.7.1 E Belongs to the glutamate synthase family
MFLELIEK_00687 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
MFLELIEK_00688 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MFLELIEK_00689 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MFLELIEK_00690 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
MFLELIEK_00691 2.7e-196 yerI S homoserine kinase type II (protein kinase fold)
MFLELIEK_00692 6.1e-123 sapB S MgtC SapB transporter
MFLELIEK_00693 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLELIEK_00694 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFLELIEK_00695 3.6e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MFLELIEK_00696 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MFLELIEK_00697 1.3e-148 yerO K Transcriptional regulator
MFLELIEK_00698 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MFLELIEK_00699 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFLELIEK_00700 1.9e-256 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFLELIEK_00701 1.1e-18 L DNA binding domain protein, excisionase family
MFLELIEK_00702 9e-101 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MFLELIEK_00703 7.1e-126 dcm 2.1.1.37, 2.1.1.72 L C-5 cytosine-specific DNA methylase
MFLELIEK_00704 7.2e-218 V AAA domain (dynein-related subfamily)
MFLELIEK_00705 6.7e-257 L LlaJI restriction endonuclease
MFLELIEK_00706 2.2e-185 E Zn peptidase
MFLELIEK_00707 6.1e-154 E Zn peptidase
MFLELIEK_00708 2.1e-109
MFLELIEK_00709 1.1e-270
MFLELIEK_00710 8.7e-148
MFLELIEK_00712 8.8e-50 S response regulator aspartate phosphatase
MFLELIEK_00713 3e-18 S Aspartate phosphatase response regulator
MFLELIEK_00715 8.9e-30 S Colicin immunity protein / pyocin immunity protein
MFLELIEK_00717 1.1e-77 S Protein of unknown function, DUF600
MFLELIEK_00718 1.6e-55 S Protein of unknown function, DUF600
MFLELIEK_00719 5.5e-51 S Protein of unknown function, DUF600
MFLELIEK_00720 0.0 L nucleic acid phosphodiester bond hydrolysis
MFLELIEK_00721 5e-171 3.4.24.40 CO amine dehydrogenase activity
MFLELIEK_00722 8.2e-210 S Tetratricopeptide repeat
MFLELIEK_00724 2.7e-126 yeeN K transcriptional regulatory protein
MFLELIEK_00726 2e-98 dhaR3 K Transcriptional regulator
MFLELIEK_00727 9.7e-82 yesE S SnoaL-like domain
MFLELIEK_00728 1.1e-145 yesF GM NAD(P)H-binding
MFLELIEK_00729 1.5e-44 cotJA S Spore coat associated protein JA (CotJA)
MFLELIEK_00730 5.6e-45 cotJB S CotJB protein
MFLELIEK_00731 5.2e-104 cotJC P Spore Coat
MFLELIEK_00732 6e-102 yesJ K Acetyltransferase (GNAT) family
MFLELIEK_00734 1.2e-101 yesL S Protein of unknown function, DUF624
MFLELIEK_00735 0.0 yesM 2.7.13.3 T Histidine kinase
MFLELIEK_00736 1.8e-201 yesN K helix_turn_helix, arabinose operon control protein
MFLELIEK_00737 6.2e-246 yesO G Bacterial extracellular solute-binding protein
MFLELIEK_00738 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
MFLELIEK_00739 2.4e-164 yesQ P Binding-protein-dependent transport system inner membrane component
MFLELIEK_00740 1e-198 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
MFLELIEK_00741 0.0 yesS K Transcriptional regulator
MFLELIEK_00742 1e-130 E GDSL-like Lipase/Acylhydrolase
MFLELIEK_00743 6e-128 yesU S Domain of unknown function (DUF1961)
MFLELIEK_00744 2.4e-110 yesV S Protein of unknown function, DUF624
MFLELIEK_00745 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MFLELIEK_00746 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
MFLELIEK_00747 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
MFLELIEK_00748 4e-64 yesZ 3.2.1.23 G beta-galactosidase activity
MFLELIEK_00749 1.6e-123 yesZ 3.2.1.23 G beta-galactosidase activity
MFLELIEK_00750 8.7e-153 yesZ 3.2.1.23 G beta-galactosidase activity
MFLELIEK_00751 0.0 yetA
MFLELIEK_00752 2.8e-290 lplA G Bacterial extracellular solute-binding protein
MFLELIEK_00753 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MFLELIEK_00754 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
MFLELIEK_00755 6e-252 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MFLELIEK_00756 5.2e-122 yetF S membrane
MFLELIEK_00757 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
MFLELIEK_00758 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_00759 2.2e-34
MFLELIEK_00760 2.7e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFLELIEK_00761 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
MFLELIEK_00762 3.4e-104 yetJ S Belongs to the BI1 family
MFLELIEK_00763 8.3e-31 yetM CH FAD binding domain
MFLELIEK_00764 6.2e-133 M Membrane
MFLELIEK_00765 6e-238 L COG3328 Transposase and inactivated derivatives
MFLELIEK_00766 3.7e-196 yetN S Protein of unknown function (DUF3900)
MFLELIEK_00767 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MFLELIEK_00768 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFLELIEK_00769 2.3e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
MFLELIEK_00770 2.1e-171 yfnG 4.2.1.45 M dehydratase
MFLELIEK_00771 1e-178 yfnF M Nucleotide-diphospho-sugar transferase
MFLELIEK_00772 1.4e-223 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
MFLELIEK_00773 5e-189 yfnD M Nucleotide-diphospho-sugar transferase
MFLELIEK_00774 3.9e-205 fsr P COG0477 Permeases of the major facilitator superfamily
MFLELIEK_00775 3.4e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MFLELIEK_00776 6.4e-241 yfnA E amino acid
MFLELIEK_00777 6.3e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFLELIEK_00778 1.1e-113 yfmS NT chemotaxis protein
MFLELIEK_00779 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFLELIEK_00780 7.5e-74 yfmQ S Uncharacterised protein from bacillus cereus group
MFLELIEK_00781 1.4e-69 yfmP K transcriptional
MFLELIEK_00782 1.5e-209 yfmO EGP Major facilitator Superfamily
MFLELIEK_00783 1.4e-34
MFLELIEK_00784 1.6e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFLELIEK_00785 2.5e-198 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
MFLELIEK_00786 5.2e-75 yfmK 2.3.1.128 K acetyltransferase
MFLELIEK_00787 2.1e-188 yfmJ S N-terminal domain of oxidoreductase
MFLELIEK_00788 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
MFLELIEK_00789 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00790 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00791 8.5e-168 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
MFLELIEK_00792 2.9e-24 S Protein of unknown function (DUF3212)
MFLELIEK_00793 2.2e-57 yflT S Heat induced stress protein YflT
MFLELIEK_00794 9.4e-239 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
MFLELIEK_00795 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
MFLELIEK_00796 1.8e-287 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFLELIEK_00797 2.2e-117 citT T response regulator
MFLELIEK_00798 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
MFLELIEK_00799 8.5e-227 citM C Citrate transporter
MFLELIEK_00800 6e-151 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
MFLELIEK_00801 5.6e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
MFLELIEK_00802 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MFLELIEK_00803 2.9e-122 yflK S protein conserved in bacteria
MFLELIEK_00804 8.9e-18 yflJ S Protein of unknown function (DUF2639)
MFLELIEK_00805 4.1e-19 yflI
MFLELIEK_00806 1.5e-49 yflH S Protein of unknown function (DUF3243)
MFLELIEK_00807 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
MFLELIEK_00808 5.7e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
MFLELIEK_00809 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFLELIEK_00810 6e-67 yhdN S Domain of unknown function (DUF1992)
MFLELIEK_00811 3.1e-251 agcS_1 E Sodium alanine symporter
MFLELIEK_00812 8.4e-25 yfkQ EG Spore germination protein
MFLELIEK_00813 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_00814 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
MFLELIEK_00815 5.1e-133 treR K transcriptional
MFLELIEK_00816 1.8e-124 yfkO C nitroreductase
MFLELIEK_00817 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MFLELIEK_00818 9.6e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
MFLELIEK_00819 6.8e-207 ydiM EGP Major facilitator Superfamily
MFLELIEK_00820 1.3e-28 yfkK S Belongs to the UPF0435 family
MFLELIEK_00821 1.2e-82 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFLELIEK_00822 2.4e-50 yfkI S gas vesicle protein
MFLELIEK_00823 9.7e-144 yihY S Belongs to the UPF0761 family
MFLELIEK_00824 5e-08
MFLELIEK_00825 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
MFLELIEK_00826 6.1e-183 cax P COG0387 Ca2 H antiporter
MFLELIEK_00827 4.5e-146 yfkD S YfkD-like protein
MFLELIEK_00828 1.2e-146 yfkC M Mechanosensitive ion channel
MFLELIEK_00829 5.4e-222 yfkA S YfkB-like domain
MFLELIEK_00830 1.1e-26 yfjT
MFLELIEK_00831 1.7e-153 pdaA G deacetylase
MFLELIEK_00832 1.7e-146 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
MFLELIEK_00833 1.7e-184 corA P Mediates influx of magnesium ions
MFLELIEK_00834 1.3e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
MFLELIEK_00835 2.6e-266 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MFLELIEK_00836 5.1e-44 S YfzA-like protein
MFLELIEK_00837 1.1e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MFLELIEK_00838 9.6e-85 yfjM S Psort location Cytoplasmic, score
MFLELIEK_00839 9.6e-28 yfjL
MFLELIEK_00840 4.4e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFLELIEK_00841 7.2e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFLELIEK_00842 6.7e-194 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFLELIEK_00843 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFLELIEK_00844 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
MFLELIEK_00845 8.3e-24 sspH S Belongs to the SspH family
MFLELIEK_00846 4e-56 yfjF S UPF0060 membrane protein
MFLELIEK_00847 1.4e-79 S Family of unknown function (DUF5381)
MFLELIEK_00848 1.8e-101 yfjD S Family of unknown function (DUF5381)
MFLELIEK_00849 4.5e-143 yfjC
MFLELIEK_00850 9.2e-191 yfjB
MFLELIEK_00851 7.4e-44 yfjA S Belongs to the WXG100 family
MFLELIEK_00852 1.9e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFLELIEK_00853 1.6e-140 glvR K Helix-turn-helix domain, rpiR family
MFLELIEK_00854 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_00855 8.4e-307 yfiB3 V ABC transporter
MFLELIEK_00856 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFLELIEK_00857 6.4e-64 mhqP S DoxX
MFLELIEK_00858 5.7e-163 yfiE 1.13.11.2 S glyoxalase
MFLELIEK_00859 1.5e-177 K AraC-like ligand binding domain
MFLELIEK_00860 1.8e-262 iolT EGP Major facilitator Superfamily
MFLELIEK_00861 8.4e-184 G Xylose isomerase
MFLELIEK_00862 1.1e-233 S Oxidoreductase
MFLELIEK_00864 1.1e-214 yxjM T Histidine kinase
MFLELIEK_00865 3.2e-113 KT LuxR family transcriptional regulator
MFLELIEK_00866 1.4e-170 V ABC transporter, ATP-binding protein
MFLELIEK_00867 2e-206 V ABC-2 family transporter protein
MFLELIEK_00868 2.6e-203 V COG0842 ABC-type multidrug transport system, permease component
MFLELIEK_00869 8.3e-99 padR K transcriptional
MFLELIEK_00870 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
MFLELIEK_00871 4.5e-197 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
MFLELIEK_00872 7.1e-107 yfiR K Transcriptional regulator
MFLELIEK_00873 1.5e-209 yfiS EGP Major facilitator Superfamily
MFLELIEK_00874 3.1e-98 yfiT S Belongs to the metal hydrolase YfiT family
MFLELIEK_00875 3.4e-283 yfiU EGP Major facilitator Superfamily
MFLELIEK_00876 5.8e-80 yfiV K transcriptional
MFLELIEK_00877 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MFLELIEK_00878 1e-176 yfiY P ABC transporter substrate-binding protein
MFLELIEK_00879 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00880 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_00881 1.8e-167 yfhB 5.3.3.17 S PhzF family
MFLELIEK_00882 1.5e-106 yfhC C nitroreductase
MFLELIEK_00883 2.1e-25 yfhD S YfhD-like protein
MFLELIEK_00885 1.6e-171 yfhF S nucleoside-diphosphate sugar epimerase
MFLELIEK_00886 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
MFLELIEK_00887 9.7e-52 yfhH S Protein of unknown function (DUF1811)
MFLELIEK_00889 1.1e-209 yfhI EGP Major facilitator Superfamily
MFLELIEK_00890 6.2e-20 sspK S reproduction
MFLELIEK_00891 2.9e-44 yfhJ S WVELL protein
MFLELIEK_00892 2.4e-87 batE T Bacterial SH3 domain homologues
MFLELIEK_00893 3.5e-51 yfhL S SdpI/YhfL protein family
MFLELIEK_00894 1.3e-170 yfhM S Alpha beta hydrolase
MFLELIEK_00895 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFLELIEK_00896 0.0 yfhO S Bacterial membrane protein YfhO
MFLELIEK_00897 1.2e-185 yfhP S membrane-bound metal-dependent
MFLELIEK_00898 1.1e-210 mutY L A G-specific
MFLELIEK_00899 6.9e-36 yfhS
MFLELIEK_00900 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_00901 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
MFLELIEK_00902 1.5e-37 ygaB S YgaB-like protein
MFLELIEK_00903 1.3e-104 ygaC J Belongs to the UPF0374 family
MFLELIEK_00904 1.8e-301 ygaD V ABC transporter
MFLELIEK_00905 8.7e-180 ygaE S Membrane
MFLELIEK_00906 2.1e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MFLELIEK_00907 4.8e-87 bcp 1.11.1.15 O Peroxiredoxin
MFLELIEK_00908 4e-80 perR P Belongs to the Fur family
MFLELIEK_00909 9.5e-56 ygzB S UPF0295 protein
MFLELIEK_00910 6.7e-167 ygxA S Nucleotidyltransferase-like
MFLELIEK_00911 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_00916 7.8e-08
MFLELIEK_00924 2e-08
MFLELIEK_00928 1e-142 spo0M S COG4326 Sporulation control protein
MFLELIEK_00929 3e-27
MFLELIEK_00930 1.3e-133 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
MFLELIEK_00932 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MFLELIEK_00934 3.5e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MFLELIEK_00935 8.7e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
MFLELIEK_00936 6.2e-169 ssuA M Sulfonate ABC transporter
MFLELIEK_00937 2.7e-146 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFLELIEK_00938 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
MFLELIEK_00940 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MFLELIEK_00941 4.1e-78 ygaO
MFLELIEK_00942 4.8e-29 K Transcriptional regulator
MFLELIEK_00944 7.9e-114 yhzB S B3/4 domain
MFLELIEK_00945 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MFLELIEK_00946 4.4e-177 yhbB S Putative amidase domain
MFLELIEK_00947 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MFLELIEK_00948 1.2e-109 yhbD K Protein of unknown function (DUF4004)
MFLELIEK_00949 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
MFLELIEK_00950 8.5e-72 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
MFLELIEK_00951 0.0 prkA T Ser protein kinase
MFLELIEK_00952 2.5e-225 yhbH S Belongs to the UPF0229 family
MFLELIEK_00953 2.2e-76 yhbI K DNA-binding transcription factor activity
MFLELIEK_00954 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
MFLELIEK_00955 3.1e-271 yhcA EGP Major facilitator Superfamily
MFLELIEK_00956 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
MFLELIEK_00957 2.8e-37 yhcC
MFLELIEK_00958 7.8e-55
MFLELIEK_00959 6.6e-60 yhcF K Transcriptional regulator
MFLELIEK_00960 1.7e-120 yhcG V ABC transporter, ATP-binding protein
MFLELIEK_00961 8.5e-165 yhcH V ABC transporter, ATP-binding protein
MFLELIEK_00962 1.5e-164 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFLELIEK_00963 1e-30 cspB K Cold-shock protein
MFLELIEK_00964 9.1e-150 metQ M Belongs to the nlpA lipoprotein family
MFLELIEK_00965 1.5e-150 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
MFLELIEK_00966 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFLELIEK_00967 7.7e-177 A Pre-toxin TG
MFLELIEK_00968 2.5e-63 S Immunity protein 70
MFLELIEK_00970 1.6e-16 S Domain of unknown function (DUF4935)
MFLELIEK_00972 2e-49 L Belongs to the 'phage' integrase family
MFLELIEK_00973 4.9e-08
MFLELIEK_00974 2.5e-27 yddA
MFLELIEK_00978 9.5e-168 yddB S Conjugative transposon protein TcpC
MFLELIEK_00979 2e-39 yddC
MFLELIEK_00980 6.1e-91 yddD S TcpE family
MFLELIEK_00981 0.0 yddE S AAA-like domain
MFLELIEK_00982 1.4e-53 S Domain of unknown function (DUF1874)
MFLELIEK_00983 0.0 yddG S maturation of SSU-rRNA
MFLELIEK_00984 1.2e-185 yddH CBM50 M Lysozyme-like
MFLELIEK_00985 8.5e-82 yddI
MFLELIEK_00986 1.8e-39 S Domain of unknown function with cystatin-like fold (DUF4467)
MFLELIEK_00987 2e-58
MFLELIEK_00988 5.7e-36
MFLELIEK_00989 1.2e-39 S Domain of unknown function (DUF4145)
MFLELIEK_00990 1.7e-69 S response regulator aspartate phosphatase
MFLELIEK_00992 2.9e-41 yhcM
MFLELIEK_00993 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFLELIEK_00994 1.2e-139 yhcP
MFLELIEK_00995 5.2e-100 yhcQ M Spore coat protein
MFLELIEK_00996 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
MFLELIEK_00997 4.2e-104 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
MFLELIEK_00998 1.5e-169 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFLELIEK_00999 2.1e-67 yhcU S Family of unknown function (DUF5365)
MFLELIEK_01000 9.9e-68 yhcV S COG0517 FOG CBS domain
MFLELIEK_01001 1e-119 yhcW 5.4.2.6 S hydrolase
MFLELIEK_01002 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFLELIEK_01003 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFLELIEK_01004 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
MFLELIEK_01005 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
MFLELIEK_01006 3e-292 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MFLELIEK_01007 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MFLELIEK_01008 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
MFLELIEK_01009 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
MFLELIEK_01010 2.2e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_01011 2.5e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
MFLELIEK_01012 1.2e-38 yhdB S YhdB-like protein
MFLELIEK_01013 4.8e-54 yhdC S Protein of unknown function (DUF3889)
MFLELIEK_01014 1.5e-187 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFLELIEK_01015 1e-75 nsrR K Transcriptional regulator
MFLELIEK_01016 3.3e-238 ygxB M Conserved TM helix
MFLELIEK_01017 6.3e-276 ycgB S Stage V sporulation protein R
MFLELIEK_01018 1.1e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
MFLELIEK_01019 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFLELIEK_01020 3.8e-162 citR K Transcriptional regulator
MFLELIEK_01021 2.9e-204 citA 2.3.3.1 C Belongs to the citrate synthase family
MFLELIEK_01022 3.9e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_01023 1e-249 yhdG E amino acid
MFLELIEK_01024 1.3e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFLELIEK_01025 7.2e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_01026 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_01027 8.1e-45 yhdK S Sigma-M inhibitor protein
MFLELIEK_01028 6.6e-201 yhdL S Sigma factor regulator N-terminal
MFLELIEK_01029 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_01030 2.4e-189 yhdN C Aldo keto reductase
MFLELIEK_01031 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFLELIEK_01032 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFLELIEK_01033 4.1e-74 cueR K transcriptional
MFLELIEK_01034 2.2e-221 yhdR 2.6.1.1 E Aminotransferase
MFLELIEK_01035 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
MFLELIEK_01036 1.7e-44 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFLELIEK_01037 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MFLELIEK_01038 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFLELIEK_01040 1.5e-203 yhdY M Mechanosensitive ion channel
MFLELIEK_01041 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
MFLELIEK_01042 1.7e-151 yheN G deacetylase
MFLELIEK_01043 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
MFLELIEK_01044 1.5e-229 nhaC C Na H antiporter
MFLELIEK_01045 2.9e-83 nhaX T Belongs to the universal stress protein A family
MFLELIEK_01046 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFLELIEK_01047 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFLELIEK_01048 4.5e-109 yheG GM NAD(P)H-binding
MFLELIEK_01049 6.3e-28 sspB S spore protein
MFLELIEK_01050 1.3e-36 yheE S Family of unknown function (DUF5342)
MFLELIEK_01051 6.3e-265 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
MFLELIEK_01052 1.6e-215 yheC HJ YheC/D like ATP-grasp
MFLELIEK_01053 6.3e-202 yheB S Belongs to the UPF0754 family
MFLELIEK_01054 9.5e-48 yheA S Belongs to the UPF0342 family
MFLELIEK_01055 7.5e-205 yhaZ L DNA alkylation repair enzyme
MFLELIEK_01056 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
MFLELIEK_01057 3.9e-292 hemZ H coproporphyrinogen III oxidase
MFLELIEK_01058 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
MFLELIEK_01059 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
MFLELIEK_01061 2.3e-131 yhaR 5.3.3.18 I enoyl-CoA hydratase
MFLELIEK_01062 1.1e-26 S YhzD-like protein
MFLELIEK_01063 4e-167 yhaQ S ABC transporter, ATP-binding protein
MFLELIEK_01064 1.2e-214 yhaP CP COG1668 ABC-type Na efflux pump, permease component
MFLELIEK_01065 3.3e-225 yhaO L DNA repair exonuclease
MFLELIEK_01066 0.0 yhaN L AAA domain
MFLELIEK_01067 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
MFLELIEK_01068 1.6e-21 yhaL S Sporulation protein YhaL
MFLELIEK_01069 1.1e-116 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MFLELIEK_01070 1.5e-89 yhaK S Putative zincin peptidase
MFLELIEK_01071 2.2e-54 yhaI S Protein of unknown function (DUF1878)
MFLELIEK_01072 1e-113 hpr K Negative regulator of protease production and sporulation
MFLELIEK_01073 7e-39 yhaH S YtxH-like protein
MFLELIEK_01074 5.4e-21
MFLELIEK_01075 3.6e-80 trpP S Tryptophan transporter TrpP
MFLELIEK_01076 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MFLELIEK_01077 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
MFLELIEK_01078 4.6e-137 ecsA V transporter (ATP-binding protein)
MFLELIEK_01079 9.2e-215 ecsB U ABC transporter
MFLELIEK_01080 1.4e-114 ecsC S EcsC protein family
MFLELIEK_01081 5.7e-230 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
MFLELIEK_01082 2.7e-231 yhfA C membrane
MFLELIEK_01083 7.9e-27 1.15.1.2 C Rubrerythrin
MFLELIEK_01084 2.9e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MFLELIEK_01085 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MFLELIEK_01086 1.6e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MFLELIEK_01087 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MFLELIEK_01088 2.2e-265 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MFLELIEK_01089 5.4e-101 yhgD K Transcriptional regulator
MFLELIEK_01090 7.8e-215 yhgE S YhgE Pip N-terminal domain protein
MFLELIEK_01091 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFLELIEK_01092 1.4e-136 yhfC S Putative membrane peptidase family (DUF2324)
MFLELIEK_01093 1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
MFLELIEK_01094 4.1e-71 3.4.13.21 S ASCH
MFLELIEK_01095 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MFLELIEK_01096 1.3e-139 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
MFLELIEK_01097 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
MFLELIEK_01098 1.9e-110 yhfK GM NmrA-like family
MFLELIEK_01099 7e-300 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MFLELIEK_01100 1.9e-65 yhfM
MFLELIEK_01101 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
MFLELIEK_01102 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
MFLELIEK_01103 7.3e-77 VY92_01935 K acetyltransferase
MFLELIEK_01104 7e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
MFLELIEK_01105 4.8e-158 yfmC M Periplasmic binding protein
MFLELIEK_01106 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MFLELIEK_01107 6.5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
MFLELIEK_01108 3.3e-272 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
MFLELIEK_01109 1.1e-90 bioY S BioY family
MFLELIEK_01110 1.7e-182 hemAT NT chemotaxis protein
MFLELIEK_01111 1e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
MFLELIEK_01112 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_01113 1.3e-32 yhzC S IDEAL
MFLELIEK_01114 9.3e-109 comK K Competence transcription factor
MFLELIEK_01115 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_01116 2.8e-39 yhjA S Excalibur calcium-binding domain
MFLELIEK_01117 2.3e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLELIEK_01118 6.9e-27 yhjC S Protein of unknown function (DUF3311)
MFLELIEK_01119 5e-60 yhjD
MFLELIEK_01120 9.1e-110 yhjE S SNARE associated Golgi protein
MFLELIEK_01121 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
MFLELIEK_01122 1.2e-280 yhjG CH FAD binding domain
MFLELIEK_01123 4.5e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_01124 3.8e-213 glcP G Major Facilitator Superfamily
MFLELIEK_01125 6e-199 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
MFLELIEK_01126 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
MFLELIEK_01127 1.8e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
MFLELIEK_01128 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
MFLELIEK_01129 1.9e-201 abrB S membrane
MFLELIEK_01130 2.1e-211 EGP Transmembrane secretion effector
MFLELIEK_01131 0.0 S Sugar transport-related sRNA regulator N-term
MFLELIEK_01132 2e-36 yhjQ C COG1145 Ferredoxin
MFLELIEK_01133 2.2e-78 yhjR S Rubrerythrin
MFLELIEK_01134 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
MFLELIEK_01135 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MFLELIEK_01136 4.5e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MFLELIEK_01137 0.0 sbcC L COG0419 ATPase involved in DNA repair
MFLELIEK_01138 1.1e-49 yisB V COG1403 Restriction endonuclease
MFLELIEK_01139 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
MFLELIEK_01140 2e-65 gerPE S Spore germination protein GerPE
MFLELIEK_01141 3.1e-23 gerPD S Spore germination protein
MFLELIEK_01142 7e-54 gerPC S Spore germination protein
MFLELIEK_01143 4e-34 gerPB S cell differentiation
MFLELIEK_01144 1.9e-33 gerPA S Spore germination protein
MFLELIEK_01145 1.5e-22 yisI S Spo0E like sporulation regulatory protein
MFLELIEK_01146 9.1e-175 cotH M Spore Coat
MFLELIEK_01147 7.1e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
MFLELIEK_01148 3.9e-57 yisL S UPF0344 protein
MFLELIEK_01149 0.0 wprA O Belongs to the peptidase S8 family
MFLELIEK_01150 1.5e-100 yisN S Protein of unknown function (DUF2777)
MFLELIEK_01151 0.0 asnO 6.3.5.4 E Asparagine synthase
MFLELIEK_01152 3.6e-111 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
MFLELIEK_01153 1.5e-242 yisQ V Mate efflux family protein
MFLELIEK_01154 1.2e-160 yisR K Transcriptional regulator
MFLELIEK_01155 1.5e-183 purR K helix_turn _helix lactose operon repressor
MFLELIEK_01156 1.5e-194 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
MFLELIEK_01157 7e-92 yisT S DinB family
MFLELIEK_01158 1.9e-107 argO S Lysine exporter protein LysE YggA
MFLELIEK_01159 1.8e-278 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
MFLELIEK_01160 4e-36 mcbG S Pentapeptide repeats (9 copies)
MFLELIEK_01161 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFLELIEK_01162 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
MFLELIEK_01163 2.5e-230 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MFLELIEK_01164 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MFLELIEK_01165 5.3e-119 comB 3.1.3.71 H Belongs to the ComB family
MFLELIEK_01166 5.4e-141 yitD 4.4.1.19 S synthase
MFLELIEK_01167 2.1e-112 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFLELIEK_01168 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFLELIEK_01169 1.5e-228 yitG EGP Major facilitator Superfamily
MFLELIEK_01170 2e-160 yitH K Acetyltransferase (GNAT) domain
MFLELIEK_01171 7.8e-79 yjcF S Acetyltransferase (GNAT) domain
MFLELIEK_01172 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MFLELIEK_01173 5.6e-54 yajQ S Belongs to the UPF0234 family
MFLELIEK_01174 6.9e-161 cvfB S protein conserved in bacteria
MFLELIEK_01175 8.5e-94
MFLELIEK_01176 1.4e-170
MFLELIEK_01177 1.5e-97 S Sporulation delaying protein SdpA
MFLELIEK_01178 1.5e-58 K Transcriptional regulator PadR-like family
MFLELIEK_01179 2e-95
MFLELIEK_01180 1.4e-44 yitR S Domain of unknown function (DUF3784)
MFLELIEK_01181 1.6e-307 nprB 3.4.24.28 E Peptidase M4
MFLELIEK_01182 8.4e-159 yitS S protein conserved in bacteria
MFLELIEK_01183 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
MFLELIEK_01184 5e-73 ipi S Intracellular proteinase inhibitor
MFLELIEK_01185 1.2e-17 S Protein of unknown function (DUF3813)
MFLELIEK_01186 2.1e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
MFLELIEK_01187 1.7e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MFLELIEK_01188 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
MFLELIEK_01189 1.5e-22 pilT S Proteolipid membrane potential modulator
MFLELIEK_01190 7.5e-269 yitY C D-arabinono-1,4-lactone oxidase
MFLELIEK_01191 5.8e-53 norB G Major Facilitator Superfamily
MFLELIEK_01192 1e-28 norB G Major Facilitator Superfamily
MFLELIEK_01193 1.1e-197 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MFLELIEK_01194 3.2e-228 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MFLELIEK_01195 1.6e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
MFLELIEK_01196 1.4e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
MFLELIEK_01197 4.4e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MFLELIEK_01198 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
MFLELIEK_01199 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MFLELIEK_01200 9.5e-28 yjzC S YjzC-like protein
MFLELIEK_01201 2.3e-16 yjzD S Protein of unknown function (DUF2929)
MFLELIEK_01202 6.8e-141 yjaU I carboxylic ester hydrolase activity
MFLELIEK_01203 1.8e-101 yjaV
MFLELIEK_01204 3.2e-183 med S Transcriptional activator protein med
MFLELIEK_01205 4.7e-25 comZ S ComZ
MFLELIEK_01206 2.7e-22 yjzB
MFLELIEK_01207 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MFLELIEK_01208 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MFLELIEK_01209 7.8e-151 yjaZ O Zn-dependent protease
MFLELIEK_01210 1.8e-184 appD P Belongs to the ABC transporter superfamily
MFLELIEK_01211 6.5e-187 appF E Belongs to the ABC transporter superfamily
MFLELIEK_01212 1.6e-251 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
MFLELIEK_01213 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01214 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01215 6.5e-147 yjbA S Belongs to the UPF0736 family
MFLELIEK_01216 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
MFLELIEK_01217 0.0 oppA E ABC transporter substrate-binding protein
MFLELIEK_01218 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01219 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01220 1.5e-197 oppD P Belongs to the ABC transporter superfamily
MFLELIEK_01221 5.5e-172 oppF E Belongs to the ABC transporter superfamily
MFLELIEK_01222 1.8e-210 yjbB EGP Major Facilitator Superfamily
MFLELIEK_01223 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_01224 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MFLELIEK_01225 6e-112 yjbE P Integral membrane protein TerC family
MFLELIEK_01226 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFLELIEK_01227 2.1e-221 yjbF S Competence protein
MFLELIEK_01228 0.0 pepF E oligoendopeptidase F
MFLELIEK_01229 1.8e-20
MFLELIEK_01230 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MFLELIEK_01231 3.7e-72 yjbI S Bacterial-like globin
MFLELIEK_01232 1e-67 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFLELIEK_01233 4.1e-101 yjbK S protein conserved in bacteria
MFLELIEK_01234 1.2e-61 yjbL S Belongs to the UPF0738 family
MFLELIEK_01235 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
MFLELIEK_01236 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFLELIEK_01237 3.4e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFLELIEK_01238 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
MFLELIEK_01239 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MFLELIEK_01240 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MFLELIEK_01241 9.3e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
MFLELIEK_01242 1.2e-213 thiO 1.4.3.19 E Glycine oxidase
MFLELIEK_01243 2.6e-29 thiS H thiamine diphosphate biosynthetic process
MFLELIEK_01244 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
MFLELIEK_01245 1.5e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFLELIEK_01246 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFLELIEK_01247 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MFLELIEK_01248 5.9e-54 yjbX S Spore coat protein
MFLELIEK_01249 5.2e-83 cotZ S Spore coat protein
MFLELIEK_01250 3.4e-96 cotY S Spore coat protein Z
MFLELIEK_01251 1.4e-38 cotX S Spore Coat Protein X and V domain
MFLELIEK_01252 1.4e-10 cotW
MFLELIEK_01253 1.4e-23 cotV S Spore Coat Protein X and V domain
MFLELIEK_01254 1.9e-56 yjcA S Protein of unknown function (DUF1360)
MFLELIEK_01257 4.9e-38 spoVIF S Stage VI sporulation protein F
MFLELIEK_01258 0.0 yjcD 3.6.4.12 L DNA helicase
MFLELIEK_01259 1.7e-38
MFLELIEK_01260 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_01261 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
MFLELIEK_01262 2.6e-137 yjcH P COG2382 Enterochelin esterase and related enzymes
MFLELIEK_01263 3.2e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFLELIEK_01264 4.2e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFLELIEK_01265 5e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
MFLELIEK_01266 5.4e-212 yjcL S Protein of unknown function (DUF819)
MFLELIEK_01269 2.1e-190 S Putative amidase domain
MFLELIEK_01270 2.6e-44 yjcN
MFLELIEK_01273 8.5e-81 L Transposase
MFLELIEK_01274 1.6e-72 yjcP
MFLELIEK_01275 4.1e-49 S YjcQ protein
MFLELIEK_01276 1.1e-92 yqaS L DNA packaging
MFLELIEK_01277 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
MFLELIEK_01278 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_01280 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
MFLELIEK_01281 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
MFLELIEK_01282 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
MFLELIEK_01283 1.6e-49 yjdF S Protein of unknown function (DUF2992)
MFLELIEK_01284 7.2e-89 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
MFLELIEK_01286 3.4e-80 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MFLELIEK_01287 4.2e-29 S Domain of unknown function (DUF4177)
MFLELIEK_01288 1e-51 yjdJ S Domain of unknown function (DUF4306)
MFLELIEK_01289 7.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFLELIEK_01291 4.6e-263 xynD 3.5.1.104 G Polysaccharide deacetylase
MFLELIEK_01292 1.8e-81 S Protein of unknown function (DUF2690)
MFLELIEK_01293 2.3e-20 yjfB S Putative motility protein
MFLELIEK_01294 9.8e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
MFLELIEK_01295 1.2e-45 T PhoQ Sensor
MFLELIEK_01296 9.9e-103 yjgB S Domain of unknown function (DUF4309)
MFLELIEK_01297 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MFLELIEK_01298 4.3e-95 yjgD S Protein of unknown function (DUF1641)
MFLELIEK_01299 8.7e-07 S Domain of unknown function (DUF4352)
MFLELIEK_01300 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
MFLELIEK_01302 1.9e-225 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
MFLELIEK_01303 7.7e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
MFLELIEK_01304 1.4e-29
MFLELIEK_01305 6.6e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MFLELIEK_01306 1.9e-122 ybbM S transport system, permease component
MFLELIEK_01307 3.7e-134 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
MFLELIEK_01308 1.1e-175 yjlA EG Putative multidrug resistance efflux transporter
MFLELIEK_01309 1.1e-89 yjlB S Cupin domain
MFLELIEK_01310 7.1e-66 yjlC S Protein of unknown function (DUF1641)
MFLELIEK_01311 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
MFLELIEK_01312 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
MFLELIEK_01313 2.7e-247 yjmB G symporter YjmB
MFLELIEK_01314 1.4e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MFLELIEK_01315 9.1e-192 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
MFLELIEK_01316 1.7e-212 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
MFLELIEK_01317 7.5e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_01318 2.4e-226 exuT G Sugar (and other) transporter
MFLELIEK_01319 1.5e-183 exuR K transcriptional
MFLELIEK_01320 1.1e-278 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
MFLELIEK_01321 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
MFLELIEK_01322 7.4e-130 MA20_18170 S membrane transporter protein
MFLELIEK_01323 2.3e-78 yjoA S DinB family
MFLELIEK_01324 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
MFLELIEK_01325 1e-212 S response regulator aspartate phosphatase
MFLELIEK_01327 4e-25 S YCII-related domain
MFLELIEK_01328 1.6e-166 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
MFLELIEK_01329 6.1e-61 yjqA S Bacterial PH domain
MFLELIEK_01330 1.3e-108 yjqB S Pfam:DUF867
MFLELIEK_01331 4.4e-160 ydbD P Catalase
MFLELIEK_01332 1.6e-111 xkdA E IrrE N-terminal-like domain
MFLELIEK_01333 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
MFLELIEK_01335 1.9e-155 xkdB K sequence-specific DNA binding
MFLELIEK_01336 2.4e-118 xkdC L Bacterial dnaA protein
MFLELIEK_01340 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
MFLELIEK_01341 6.3e-85 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
MFLELIEK_01342 4.8e-140 xtmA L phage terminase small subunit
MFLELIEK_01343 1.2e-252 xtmB S phage terminase, large subunit
MFLELIEK_01344 1.6e-285 yqbA S portal protein
MFLELIEK_01345 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MFLELIEK_01346 5.8e-169 xkdG S Phage capsid family
MFLELIEK_01347 5.6e-62 yqbG S Protein of unknown function (DUF3199)
MFLELIEK_01348 8.7e-65 yqbH S Domain of unknown function (DUF3599)
MFLELIEK_01349 1.1e-86 xkdI S Bacteriophage HK97-gp10, putative tail-component
MFLELIEK_01350 1.9e-77 xkdJ
MFLELIEK_01351 4.2e-256 xkdK S Phage tail sheath C-terminal domain
MFLELIEK_01352 6.1e-76 xkdM S Phage tail tube protein
MFLELIEK_01353 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
MFLELIEK_01354 9.3e-274 xkdO L Transglycosylase SLT domain
MFLELIEK_01355 4.1e-121 xkdP S Lysin motif
MFLELIEK_01356 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
MFLELIEK_01357 2.1e-39 xkdR S Protein of unknown function (DUF2577)
MFLELIEK_01358 3.1e-69 xkdS S Protein of unknown function (DUF2634)
MFLELIEK_01359 6.7e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MFLELIEK_01360 1.2e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MFLELIEK_01361 1.5e-40
MFLELIEK_01362 1e-261
MFLELIEK_01363 5.4e-53 xkdW S XkdW protein
MFLELIEK_01364 5.5e-22 xkdX
MFLELIEK_01365 1.7e-151 xepA
MFLELIEK_01366 6.2e-39 xhlA S Haemolysin XhlA
MFLELIEK_01367 9.3e-40 xhlB S SPP1 phage holin
MFLELIEK_01368 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_01369 6.7e-23 spoIISB S Stage II sporulation protein SB
MFLELIEK_01370 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
MFLELIEK_01371 5.8e-175 pit P phosphate transporter
MFLELIEK_01372 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
MFLELIEK_01373 4e-240 steT E amino acid
MFLELIEK_01374 1e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
MFLELIEK_01375 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFLELIEK_01376 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFLELIEK_01378 9.8e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFLELIEK_01379 6.9e-134 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
MFLELIEK_01380 2.5e-152 dppA E D-aminopeptidase
MFLELIEK_01381 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01382 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MFLELIEK_01383 1.3e-187 dppD P Belongs to the ABC transporter superfamily
MFLELIEK_01384 0.0 dppE E ABC transporter substrate-binding protein
MFLELIEK_01386 4.5e-177 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
MFLELIEK_01387 4.4e-200 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MFLELIEK_01388 3.1e-164 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFLELIEK_01389 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
MFLELIEK_01390 3.1e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
MFLELIEK_01391 1.2e-160 ykgA E Amidinotransferase
MFLELIEK_01392 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
MFLELIEK_01393 1.7e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MFLELIEK_01394 5.5e-09
MFLELIEK_01395 2.3e-128 ykjA S Protein of unknown function (DUF421)
MFLELIEK_01396 4.8e-96 ykkA S Protein of unknown function (DUF664)
MFLELIEK_01397 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFLELIEK_01398 3.5e-55 ykkC P Multidrug resistance protein
MFLELIEK_01399 7e-50 ykkD P Multidrug resistance protein
MFLELIEK_01400 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
MFLELIEK_01401 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFLELIEK_01402 8.1e-227 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MFLELIEK_01403 1.3e-70 ohrA O Organic hydroperoxide resistance protein
MFLELIEK_01404 4.8e-73 ohrR K COG1846 Transcriptional regulators
MFLELIEK_01405 2.4e-71 ohrB O Organic hydroperoxide resistance protein
MFLELIEK_01406 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
MFLELIEK_01407 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MFLELIEK_01408 1.5e-175 isp O Belongs to the peptidase S8 family
MFLELIEK_01409 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFLELIEK_01410 5.3e-136 ykoC P Cobalt transport protein
MFLELIEK_01411 1.6e-302 P ABC transporter, ATP-binding protein
MFLELIEK_01412 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
MFLELIEK_01413 5.1e-110 ykoF S YKOF-related Family
MFLELIEK_01414 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_01415 2e-242 ykoH 2.7.13.3 T Histidine kinase
MFLELIEK_01416 1.2e-112 ykoI S Peptidase propeptide and YPEB domain
MFLELIEK_01417 2.2e-85 ykoJ S Peptidase propeptide and YPEB domain
MFLELIEK_01420 2.2e-222 mgtE P Acts as a magnesium transporter
MFLELIEK_01421 1.4e-53 tnrA K transcriptional
MFLELIEK_01422 5.9e-18
MFLELIEK_01423 6.9e-26 ykoL
MFLELIEK_01424 1.3e-81 mhqR K transcriptional
MFLELIEK_01425 8.9e-217 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
MFLELIEK_01426 2.7e-97 ykoP G polysaccharide deacetylase
MFLELIEK_01427 2.3e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
MFLELIEK_01428 0.0 ykoS
MFLELIEK_01429 2.1e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFLELIEK_01430 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
MFLELIEK_01431 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
MFLELIEK_01432 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
MFLELIEK_01433 5.4e-110 ykoX S membrane-associated protein
MFLELIEK_01434 8.7e-176 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
MFLELIEK_01435 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_01436 1.7e-106 rsgI S Anti-sigma factor N-terminus
MFLELIEK_01437 1.9e-26 sspD S small acid-soluble spore protein
MFLELIEK_01438 2.5e-124 ykrK S Domain of unknown function (DUF1836)
MFLELIEK_01439 3.5e-155 htpX O Belongs to the peptidase M48B family
MFLELIEK_01440 4.8e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
MFLELIEK_01441 1.2e-10 ydfR S Protein of unknown function (DUF421)
MFLELIEK_01442 4.1e-18 ykzE
MFLELIEK_01443 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
MFLELIEK_01444 0.0 kinE 2.7.13.3 T Histidine kinase
MFLELIEK_01445 7.8e-88 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MFLELIEK_01447 1.4e-195 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
MFLELIEK_01448 2.4e-228 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
MFLELIEK_01449 1e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
MFLELIEK_01450 1.5e-230 mtnE 2.6.1.83 E Aminotransferase
MFLELIEK_01451 1.4e-228 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
MFLELIEK_01452 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
MFLELIEK_01453 1.6e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
MFLELIEK_01454 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
MFLELIEK_01455 4.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
MFLELIEK_01456 6.4e-09 S Spo0E like sporulation regulatory protein
MFLELIEK_01457 1.8e-64 eag
MFLELIEK_01458 1.6e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
MFLELIEK_01459 1.3e-75 ykvE K transcriptional
MFLELIEK_01460 2.5e-125 motB N Flagellar motor protein
MFLELIEK_01461 1e-137 motA N flagellar motor
MFLELIEK_01462 0.0 clpE O Belongs to the ClpA ClpB family
MFLELIEK_01463 2.6e-178 ykvI S membrane
MFLELIEK_01464 9.5e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MFLELIEK_01465 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
MFLELIEK_01466 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
MFLELIEK_01467 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MFLELIEK_01468 2e-61 ykvN K Transcriptional regulator
MFLELIEK_01469 2.4e-133 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_01470 9.9e-216 ykvP 3.5.1.28 M Glycosyl transferases group 1
MFLELIEK_01471 3.5e-35 3.5.1.104 M LysM domain
MFLELIEK_01472 1.4e-162 G Glycosyl hydrolases family 18
MFLELIEK_01473 5.6e-46 ykvR S Protein of unknown function (DUF3219)
MFLELIEK_01474 6e-25 ykvS S protein conserved in bacteria
MFLELIEK_01475 2.8e-28
MFLELIEK_01476 3.1e-102 ykvT 3.5.1.28 M Cell Wall Hydrolase
MFLELIEK_01477 3.8e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_01478 1.6e-88 stoA CO thiol-disulfide
MFLELIEK_01479 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MFLELIEK_01480 2.3e-09
MFLELIEK_01481 1.3e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MFLELIEK_01482 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
MFLELIEK_01484 2.2e-127 glcT K antiterminator
MFLELIEK_01485 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_01486 2.1e-39 ptsH G phosphocarrier protein HPr
MFLELIEK_01487 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MFLELIEK_01488 7.2e-39 splA S Transcriptional regulator
MFLELIEK_01489 1.3e-201 splB 4.1.99.14 L Spore photoproduct lyase
MFLELIEK_01490 6.6e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_01491 4.1e-257 mcpC NT chemotaxis protein
MFLELIEK_01492 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
MFLELIEK_01493 3e-123 ykwD J protein with SCP PR1 domains
MFLELIEK_01494 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
MFLELIEK_01495 0.0 pilS 2.7.13.3 T Histidine kinase
MFLELIEK_01496 2e-222 patA 2.6.1.1 E Aminotransferase
MFLELIEK_01497 2.2e-15
MFLELIEK_01498 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
MFLELIEK_01499 1.7e-84 ykyB S YkyB-like protein
MFLELIEK_01500 1.7e-235 ykuC EGP Major facilitator Superfamily
MFLELIEK_01501 1.8e-87 ykuD S protein conserved in bacteria
MFLELIEK_01502 9.4e-166 ykuE S Metallophosphoesterase
MFLELIEK_01503 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_01504 5.2e-234 ykuI T Diguanylate phosphodiesterase
MFLELIEK_01505 3.9e-37 ykuJ S protein conserved in bacteria
MFLELIEK_01506 4.4e-94 ykuK S Ribonuclease H-like
MFLELIEK_01507 3.9e-27 ykzF S Antirepressor AbbA
MFLELIEK_01508 1.6e-76 ykuL S CBS domain
MFLELIEK_01509 3.5e-168 ccpC K Transcriptional regulator
MFLELIEK_01510 1.6e-85 fld C Flavodoxin domain
MFLELIEK_01511 5.2e-175 ykuO
MFLELIEK_01512 8.7e-78 fld C Flavodoxin
MFLELIEK_01513 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MFLELIEK_01514 2.7e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MFLELIEK_01515 9e-37 ykuS S Belongs to the UPF0180 family
MFLELIEK_01516 8.8e-142 ykuT M Mechanosensitive ion channel
MFLELIEK_01517 3.9e-101 ykuU O Alkyl hydroperoxide reductase
MFLELIEK_01518 1.4e-80 ykuV CO thiol-disulfide
MFLELIEK_01519 5.8e-95 rok K Repressor of ComK
MFLELIEK_01520 1.6e-145 yknT
MFLELIEK_01521 2.4e-107 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MFLELIEK_01522 4.5e-191 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
MFLELIEK_01523 3.4e-244 moeA 2.10.1.1 H molybdopterin
MFLELIEK_01524 9.3e-92 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MFLELIEK_01525 7.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
MFLELIEK_01526 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
MFLELIEK_01527 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFLELIEK_01528 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
MFLELIEK_01529 2.9e-117 yknW S Yip1 domain
MFLELIEK_01530 7.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MFLELIEK_01531 2.5e-124 macB V ABC transporter, ATP-binding protein
MFLELIEK_01532 1.1e-207 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFLELIEK_01533 3.1e-136 fruR K Transcriptional regulator
MFLELIEK_01534 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
MFLELIEK_01535 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MFLELIEK_01536 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFLELIEK_01537 8.1e-39 ykoA
MFLELIEK_01538 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
MFLELIEK_01539 1.3e-165 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFLELIEK_01540 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
MFLELIEK_01541 1.1e-12 S Uncharacterized protein YkpC
MFLELIEK_01542 7.7e-183 mreB D Rod-share determining protein MreBH
MFLELIEK_01543 1.5e-43 abrB K of stationary sporulation gene expression
MFLELIEK_01544 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
MFLELIEK_01545 6.8e-161 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
MFLELIEK_01546 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
MFLELIEK_01547 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MFLELIEK_01548 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFLELIEK_01549 8.2e-31 ykzG S Belongs to the UPF0356 family
MFLELIEK_01550 1.4e-147 ykrA S hydrolases of the HAD superfamily
MFLELIEK_01551 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFLELIEK_01553 2e-115 recN L Putative cell-wall binding lipoprotein
MFLELIEK_01554 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFLELIEK_01555 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFLELIEK_01556 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFLELIEK_01557 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFLELIEK_01558 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
MFLELIEK_01559 3.5e-277 speA 4.1.1.19 E Arginine
MFLELIEK_01560 1.6e-42 yktA S Belongs to the UPF0223 family
MFLELIEK_01561 2.1e-117 yktB S Belongs to the UPF0637 family
MFLELIEK_01562 7.1e-26 ykzI
MFLELIEK_01563 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
MFLELIEK_01564 2.2e-76 ykzC S Acetyltransferase (GNAT) family
MFLELIEK_01565 8.7e-170 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
MFLELIEK_01566 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
MFLELIEK_01567 0.0 ylaA
MFLELIEK_01568 2.7e-42 ylaB
MFLELIEK_01569 2.5e-89 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_01570 7.1e-12 sigC S Putative zinc-finger
MFLELIEK_01571 4.1e-38 ylaE
MFLELIEK_01572 8.2e-22 S Family of unknown function (DUF5325)
MFLELIEK_01573 0.0 typA T GTP-binding protein TypA
MFLELIEK_01574 5.6e-47 ylaH S YlaH-like protein
MFLELIEK_01575 2.5e-32 ylaI S protein conserved in bacteria
MFLELIEK_01576 4.4e-88 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFLELIEK_01577 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
MFLELIEK_01578 1e-84 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MFLELIEK_01579 4.7e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
MFLELIEK_01580 8.7e-44 ylaN S Belongs to the UPF0358 family
MFLELIEK_01581 2.5e-212 ftsW D Belongs to the SEDS family
MFLELIEK_01582 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MFLELIEK_01583 6.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
MFLELIEK_01584 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
MFLELIEK_01585 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
MFLELIEK_01586 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFLELIEK_01587 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
MFLELIEK_01588 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
MFLELIEK_01589 1.5e-166 ctaG S cytochrome c oxidase
MFLELIEK_01590 7e-62 ylbA S YugN-like family
MFLELIEK_01591 4.4e-74 ylbB T COG0517 FOG CBS domain
MFLELIEK_01592 4.3e-200 ylbC S protein with SCP PR1 domains
MFLELIEK_01593 2e-62 ylbD S Putative coat protein
MFLELIEK_01594 6.7e-37 ylbE S YlbE-like protein
MFLELIEK_01595 1.8e-75 ylbF S Belongs to the UPF0342 family
MFLELIEK_01596 7.5e-39 ylbG S UPF0298 protein
MFLELIEK_01597 2.7e-97 rsmD 2.1.1.171 L Methyltransferase
MFLELIEK_01598 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MFLELIEK_01599 9.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
MFLELIEK_01600 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
MFLELIEK_01601 6.8e-187 ylbL T Belongs to the peptidase S16 family
MFLELIEK_01602 4.3e-228 ylbM S Belongs to the UPF0348 family
MFLELIEK_01604 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
MFLELIEK_01605 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MFLELIEK_01606 7.5e-74 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
MFLELIEK_01607 1.5e-88 ylbP K n-acetyltransferase
MFLELIEK_01608 1.8e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MFLELIEK_01609 5.1e-306 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
MFLELIEK_01610 2.9e-78 mraZ K Belongs to the MraZ family
MFLELIEK_01611 7.3e-172 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MFLELIEK_01612 3.7e-44 ftsL D Essential cell division protein
MFLELIEK_01613 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MFLELIEK_01614 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
MFLELIEK_01615 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MFLELIEK_01616 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MFLELIEK_01617 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MFLELIEK_01618 5.7e-186 spoVE D Belongs to the SEDS family
MFLELIEK_01619 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MFLELIEK_01620 5.3e-167 murB 1.3.1.98 M cell wall formation
MFLELIEK_01621 1.7e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MFLELIEK_01622 4.1e-103 ylxW S protein conserved in bacteria
MFLELIEK_01623 1.8e-91 ylxX S protein conserved in bacteria
MFLELIEK_01624 6.2e-58 sbp S small basic protein
MFLELIEK_01625 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MFLELIEK_01626 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MFLELIEK_01627 0.0 bpr O COG1404 Subtilisin-like serine proteases
MFLELIEK_01629 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
MFLELIEK_01630 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_01631 6.2e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_01632 3.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
MFLELIEK_01633 6.8e-253 argE 3.5.1.16 E Acetylornithine deacetylase
MFLELIEK_01634 2.4e-37 ylmC S sporulation protein
MFLELIEK_01635 5.9e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
MFLELIEK_01636 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MFLELIEK_01637 1.4e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MFLELIEK_01638 1.6e-39 yggT S membrane
MFLELIEK_01639 7.5e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
MFLELIEK_01640 2.6e-67 divIVA D Cell division initiation protein
MFLELIEK_01641 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MFLELIEK_01642 3.8e-63 dksA T COG1734 DnaK suppressor protein
MFLELIEK_01643 4e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MFLELIEK_01644 3.5e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MFLELIEK_01645 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MFLELIEK_01646 5.4e-229 pyrP F Xanthine uracil
MFLELIEK_01647 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MFLELIEK_01648 4.1e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MFLELIEK_01649 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MFLELIEK_01650 0.0 carB 6.3.5.5 F Belongs to the CarB family
MFLELIEK_01651 1.4e-144 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
MFLELIEK_01652 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MFLELIEK_01653 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MFLELIEK_01654 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MFLELIEK_01656 1.7e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
MFLELIEK_01657 1.2e-178 cysP P phosphate transporter
MFLELIEK_01658 1.5e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
MFLELIEK_01659 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
MFLELIEK_01660 1.1e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
MFLELIEK_01661 2.2e-145 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
MFLELIEK_01662 6.3e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
MFLELIEK_01663 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
MFLELIEK_01664 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
MFLELIEK_01665 3.1e-156 yloC S stress-induced protein
MFLELIEK_01666 1.5e-40 ylzA S Belongs to the UPF0296 family
MFLELIEK_01667 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MFLELIEK_01668 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MFLELIEK_01669 1.4e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MFLELIEK_01670 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MFLELIEK_01671 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MFLELIEK_01672 5.2e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MFLELIEK_01673 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MFLELIEK_01674 1.4e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MFLELIEK_01675 1.6e-140 stp 3.1.3.16 T phosphatase
MFLELIEK_01676 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MFLELIEK_01677 2.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MFLELIEK_01678 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MFLELIEK_01679 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
MFLELIEK_01680 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MFLELIEK_01681 5.5e-59 asp S protein conserved in bacteria
MFLELIEK_01682 1.3e-299 yloV S kinase related to dihydroxyacetone kinase
MFLELIEK_01683 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
MFLELIEK_01684 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
MFLELIEK_01685 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MFLELIEK_01686 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
MFLELIEK_01687 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MFLELIEK_01688 2.7e-169 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
MFLELIEK_01689 6.7e-128 IQ reductase
MFLELIEK_01690 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MFLELIEK_01691 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MFLELIEK_01692 0.0 smc D Required for chromosome condensation and partitioning
MFLELIEK_01693 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MFLELIEK_01694 2.9e-87
MFLELIEK_01695 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MFLELIEK_01696 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MFLELIEK_01697 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MFLELIEK_01698 4.5e-36 ylqC S Belongs to the UPF0109 family
MFLELIEK_01699 6.3e-61 ylqD S YlqD protein
MFLELIEK_01700 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MFLELIEK_01701 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MFLELIEK_01702 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MFLELIEK_01703 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MFLELIEK_01704 1.5e-135 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFLELIEK_01705 1.4e-288 ylqG
MFLELIEK_01706 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
MFLELIEK_01707 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
MFLELIEK_01708 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MFLELIEK_01709 5e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
MFLELIEK_01710 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MFLELIEK_01711 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MFLELIEK_01712 2.5e-169 xerC L tyrosine recombinase XerC
MFLELIEK_01713 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MFLELIEK_01714 2.2e-241 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MFLELIEK_01715 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MFLELIEK_01716 8.8e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
MFLELIEK_01717 2e-74 flgC N Belongs to the flagella basal body rod proteins family
MFLELIEK_01718 1.9e-31 fliE N Flagellar hook-basal body
MFLELIEK_01719 7.7e-254 fliF N The M ring may be actively involved in energy transduction
MFLELIEK_01720 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFLELIEK_01721 3.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
MFLELIEK_01722 2.1e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
MFLELIEK_01723 1.5e-69 fliJ N Flagellar biosynthesis chaperone
MFLELIEK_01724 1.3e-36 ylxF S MgtE intracellular N domain
MFLELIEK_01725 1.7e-215 fliK N Flagellar hook-length control protein
MFLELIEK_01726 2.3e-72 flgD N Flagellar basal body rod modification protein
MFLELIEK_01727 1.9e-136 flgG N Flagellar basal body rod
MFLELIEK_01728 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
MFLELIEK_01729 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
MFLELIEK_01730 1.1e-174 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
MFLELIEK_01731 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
MFLELIEK_01732 6e-96 fliZ N Flagellar biosynthesis protein, FliO
MFLELIEK_01733 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
MFLELIEK_01734 2.2e-36 fliQ N Role in flagellar biosynthesis
MFLELIEK_01735 3.6e-132 fliR N Flagellar biosynthetic protein FliR
MFLELIEK_01736 4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFLELIEK_01737 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
MFLELIEK_01738 6.8e-201 flhF N Flagellar biosynthesis regulator FlhF
MFLELIEK_01739 2.8e-157 flhG D Belongs to the ParA family
MFLELIEK_01740 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
MFLELIEK_01741 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
MFLELIEK_01742 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
MFLELIEK_01743 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
MFLELIEK_01744 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
MFLELIEK_01745 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_01746 1.3e-77 ylxL
MFLELIEK_01747 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
MFLELIEK_01748 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MFLELIEK_01749 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MFLELIEK_01750 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MFLELIEK_01751 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MFLELIEK_01752 2.7e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MFLELIEK_01753 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
MFLELIEK_01754 7.7e-233 rasP M zinc metalloprotease
MFLELIEK_01755 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MFLELIEK_01756 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MFLELIEK_01757 1.6e-79 rimP S Required for maturation of 30S ribosomal subunits
MFLELIEK_01758 1.1e-203 nusA K Participates in both transcription termination and antitermination
MFLELIEK_01759 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
MFLELIEK_01760 3.1e-47 ylxQ J ribosomal protein
MFLELIEK_01761 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MFLELIEK_01762 3.9e-44 ylxP S protein conserved in bacteria
MFLELIEK_01763 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MFLELIEK_01764 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MFLELIEK_01765 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MFLELIEK_01766 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MFLELIEK_01767 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
MFLELIEK_01768 9.8e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
MFLELIEK_01769 4.4e-233 pepR S Belongs to the peptidase M16 family
MFLELIEK_01770 2.6e-42 ymxH S YlmC YmxH family
MFLELIEK_01771 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
MFLELIEK_01772 2.2e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
MFLELIEK_01773 1.2e-191 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MFLELIEK_01774 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MFLELIEK_01775 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MFLELIEK_01776 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MFLELIEK_01777 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
MFLELIEK_01778 4.4e-32 S YlzJ-like protein
MFLELIEK_01779 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MFLELIEK_01780 1.4e-133 ymfC K Transcriptional regulator
MFLELIEK_01781 3.8e-205 ymfD EGP Major facilitator Superfamily
MFLELIEK_01782 2.5e-231 ymfF S Peptidase M16
MFLELIEK_01783 1.9e-242 ymfH S zinc protease
MFLELIEK_01784 1.7e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
MFLELIEK_01785 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
MFLELIEK_01786 2.7e-143 ymfK S Protein of unknown function (DUF3388)
MFLELIEK_01787 1.9e-124 ymfM S protein conserved in bacteria
MFLELIEK_01788 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MFLELIEK_01789 2.1e-235 cinA 3.5.1.42 S Belongs to the CinA family
MFLELIEK_01790 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MFLELIEK_01791 2e-211 pbpX V Beta-lactamase
MFLELIEK_01792 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
MFLELIEK_01793 5.5e-152 ymdB S protein conserved in bacteria
MFLELIEK_01794 1.2e-36 spoVS S Stage V sporulation protein S
MFLELIEK_01795 1.9e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
MFLELIEK_01796 3e-215 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFLELIEK_01797 8.5e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MFLELIEK_01798 3.5e-68 ymcA 3.6.3.21 S Belongs to the UPF0342 family
MFLELIEK_01799 2.2e-88 cotE S Spore coat protein
MFLELIEK_01800 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MFLELIEK_01801 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MFLELIEK_01806 9.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
MFLELIEK_01807 2.6e-73 L Phage integrase family
MFLELIEK_01808 2.3e-15 S PIN domain
MFLELIEK_01809 9.7e-21
MFLELIEK_01811 2.2e-59 S HNH endonuclease
MFLELIEK_01812 3.8e-08
MFLELIEK_01813 1.1e-68 S Phage terminase, small subunit
MFLELIEK_01814 4.6e-08 S Terminase
MFLELIEK_01815 5.1e-70 S Regulatory protein YrvL
MFLELIEK_01817 7.9e-97 ymcC S Membrane
MFLELIEK_01818 3.3e-104 pksA K Transcriptional regulator
MFLELIEK_01819 4.4e-61 ymzB
MFLELIEK_01820 2.8e-162 ymaE S Metallo-beta-lactamase superfamily
MFLELIEK_01821 8.6e-251 aprX O Belongs to the peptidase S8 family
MFLELIEK_01822 1.9e-07 K Transcriptional regulator
MFLELIEK_01823 2.1e-126 ymaC S Replication protein
MFLELIEK_01824 1e-78 ymaD O redox protein, regulator of disulfide bond formation
MFLELIEK_01825 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
MFLELIEK_01826 4.9e-51 ebrA P Small Multidrug Resistance protein
MFLELIEK_01828 2.1e-46 ymaF S YmaF family
MFLELIEK_01829 7.9e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MFLELIEK_01830 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
MFLELIEK_01831 8.2e-23
MFLELIEK_01832 4.5e-22 ymzA
MFLELIEK_01833 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
MFLELIEK_01834 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFLELIEK_01835 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MFLELIEK_01836 2e-109 ymaB
MFLELIEK_01837 1.5e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_01838 1.7e-176 spoVK O stage V sporulation protein K
MFLELIEK_01839 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MFLELIEK_01840 4.8e-243 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
MFLELIEK_01841 1.1e-68 glnR K transcriptional
MFLELIEK_01842 7e-261 glnA 6.3.1.2 E glutamine synthetase
MFLELIEK_01843 1.1e-09
MFLELIEK_01844 1.6e-31
MFLELIEK_01845 2.1e-16
MFLELIEK_01846 8.9e-90 G SMI1-KNR4 cell-wall
MFLELIEK_01847 3.1e-113 ynaC
MFLELIEK_01848 4.1e-11 S Protein of unknown function (DUF1433)
MFLELIEK_01849 2e-97 ynaD J Acetyltransferase (GNAT) domain
MFLELIEK_01851 4.7e-75 S CAAX protease self-immunity
MFLELIEK_01852 4.7e-08 S Uncharacterised protein family (UPF0715)
MFLELIEK_01853 5.5e-20 K Cro/C1-type HTH DNA-binding domain
MFLELIEK_01854 6.4e-111 ynaE S Domain of unknown function (DUF3885)
MFLELIEK_01855 8.6e-15 ynaF
MFLELIEK_01857 8.7e-81 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
MFLELIEK_01858 7.9e-255 xynT G MFS/sugar transport protein
MFLELIEK_01859 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
MFLELIEK_01860 6.8e-212 xylR GK ROK family
MFLELIEK_01861 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
MFLELIEK_01862 1.3e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
MFLELIEK_01863 3.7e-111 yokF 3.1.31.1 L RNA catabolic process
MFLELIEK_01864 1.4e-254 iolT EGP Major facilitator Superfamily
MFLELIEK_01865 4.5e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MFLELIEK_01867 1.4e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
MFLELIEK_01868 5.2e-15
MFLELIEK_01871 2.5e-163 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MFLELIEK_01873 8.9e-128 S Domain of unknown function, YrpD
MFLELIEK_01876 7.9e-25 tatA U protein secretion
MFLELIEK_01877 1.8e-71
MFLELIEK_01878 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
MFLELIEK_01881 2.8e-52 gerAA EG Spore germination protein
MFLELIEK_01882 4.8e-144 gerAA EG Spore germination protein
MFLELIEK_01883 3.4e-88 gerLC S Spore germination protein
MFLELIEK_01884 7.2e-152 yndG S DoxX-like family
MFLELIEK_01885 8e-114 yndH S Domain of unknown function (DUF4166)
MFLELIEK_01886 1.6e-307 yndJ S YndJ-like protein
MFLELIEK_01889 1.5e-135 yndL S Replication protein
MFLELIEK_01890 6.4e-73 yndM S Protein of unknown function (DUF2512)
MFLELIEK_01891 2.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
MFLELIEK_01892 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MFLELIEK_01893 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
MFLELIEK_01894 2.5e-110 yneB L resolvase
MFLELIEK_01895 4.8e-32 ynzC S UPF0291 protein
MFLELIEK_01896 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MFLELIEK_01897 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
MFLELIEK_01898 1.8e-28 yneF S UPF0154 protein
MFLELIEK_01899 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
MFLELIEK_01900 7.1e-127 ccdA O cytochrome c biogenesis protein
MFLELIEK_01901 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
MFLELIEK_01902 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
MFLELIEK_01903 4.2e-74 yneK S Protein of unknown function (DUF2621)
MFLELIEK_01904 1.2e-64 hspX O Spore coat protein
MFLELIEK_01905 3.9e-19 sspP S Belongs to the SspP family
MFLELIEK_01906 2.2e-14 sspO S Belongs to the SspO family
MFLELIEK_01907 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MFLELIEK_01908 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MFLELIEK_01910 3.1e-08 sspN S Small acid-soluble spore protein N family
MFLELIEK_01911 3.9e-35 tlp S Belongs to the Tlp family
MFLELIEK_01912 2e-73 yneP S Thioesterase-like superfamily
MFLELIEK_01913 1.7e-53 yneQ
MFLELIEK_01914 4.1e-49 yneR S Belongs to the HesB IscA family
MFLELIEK_01915 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MFLELIEK_01916 8.6e-69 yccU S CoA-binding protein
MFLELIEK_01917 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFLELIEK_01918 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MFLELIEK_01919 2.3e-12
MFLELIEK_01920 1.3e-57 ynfC
MFLELIEK_01921 5.3e-251 agcS E Sodium alanine symporter
MFLELIEK_01922 1.7e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
MFLELIEK_01924 1.2e-249 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
MFLELIEK_01925 5e-295 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
MFLELIEK_01926 2e-79 yngA S membrane
MFLELIEK_01927 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFLELIEK_01928 5.5e-104 yngC S membrane-associated protein
MFLELIEK_01929 2.5e-233 nrnB S phosphohydrolase (DHH superfamily)
MFLELIEK_01930 1.3e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFLELIEK_01931 7.1e-136 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MFLELIEK_01932 3.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
MFLELIEK_01933 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
MFLELIEK_01934 8.1e-249 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
MFLELIEK_01935 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFLELIEK_01936 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
MFLELIEK_01937 1.7e-303 yngK T Glycosyl hydrolase-like 10
MFLELIEK_01938 1.1e-63 yngL S Protein of unknown function (DUF1360)
MFLELIEK_01939 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MFLELIEK_01940 3.3e-31 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
MFLELIEK_01941 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_01942 2.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
MFLELIEK_01943 4e-189 yoxA 5.1.3.3 G Aldose 1-epimerase
MFLELIEK_01944 8.7e-246 yoeA V MATE efflux family protein
MFLELIEK_01945 9.1e-98 yoeB S IseA DL-endopeptidase inhibitor
MFLELIEK_01947 2.2e-96 L Integrase
MFLELIEK_01948 3e-34 yoeD G Helix-turn-helix domain
MFLELIEK_01949 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MFLELIEK_01950 4.4e-155 gltR1 K Transcriptional regulator
MFLELIEK_01951 4e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
MFLELIEK_01952 1e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
MFLELIEK_01953 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
MFLELIEK_01954 7.8e-155 gltC K Transcriptional regulator
MFLELIEK_01955 8.6e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MFLELIEK_01956 3.6e-143 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFLELIEK_01957 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
MFLELIEK_01958 3.7e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_01959 1.3e-37 yoxC S Bacterial protein of unknown function (DUF948)
MFLELIEK_01960 8.5e-134 yoxB
MFLELIEK_01961 1.9e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFLELIEK_01962 1.2e-124 V ABC-2 family transporter protein
MFLELIEK_01963 1.3e-94 V ABC-2 family transporter protein
MFLELIEK_01964 3.3e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
MFLELIEK_01965 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_01966 7.6e-233 yoaB EGP Major facilitator Superfamily
MFLELIEK_01967 3.3e-280 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
MFLELIEK_01968 4.4e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLELIEK_01969 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFLELIEK_01970 1.1e-33 yoaF
MFLELIEK_01971 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
MFLELIEK_01972 7e-14
MFLELIEK_01973 1.5e-38 S Protein of unknown function (DUF4025)
MFLELIEK_01974 1.7e-187 mcpU NT methyl-accepting chemotaxis protein
MFLELIEK_01975 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
MFLELIEK_01976 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
MFLELIEK_01977 2.3e-111 yoaK S Membrane
MFLELIEK_01978 2.8e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
MFLELIEK_01979 4.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
MFLELIEK_01981 7.9e-232 oxdC 4.1.1.2 G Oxalate decarboxylase
MFLELIEK_01984 7.3e-86
MFLELIEK_01985 9.3e-172 yoaR V vancomycin resistance protein
MFLELIEK_01986 2.8e-74 yoaS S Protein of unknown function (DUF2975)
MFLELIEK_01987 4.4e-30 yozG K Transcriptional regulator
MFLELIEK_01988 1.5e-146 yoaT S Protein of unknown function (DUF817)
MFLELIEK_01989 8.6e-159 yoaU K LysR substrate binding domain
MFLELIEK_01990 1.5e-158 yijE EG EamA-like transporter family
MFLELIEK_01991 1.8e-77 yoaW
MFLELIEK_01992 4.3e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
MFLELIEK_01993 1.2e-166 bla 3.5.2.6 V beta-lactamase
MFLELIEK_01996 1.1e-237 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MFLELIEK_01997 5.3e-139 pps 2.7.9.2 GT phosphoenolpyruvate synthase
MFLELIEK_01998 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
MFLELIEK_02000 1.4e-37 S TM2 domain
MFLELIEK_02002 1.3e-31 yoaF
MFLELIEK_02003 2.6e-136
MFLELIEK_02004 1.7e-16 FG Scavenger mRNA decapping enzyme C-term binding
MFLELIEK_02011 3.7e-51 ynaF
MFLELIEK_02012 4.6e-101 ynaE S Domain of unknown function (DUF3885)
MFLELIEK_02013 9.4e-26 K Cro/C1-type HTH DNA-binding domain
MFLELIEK_02014 6.2e-81 yoaW
MFLELIEK_02015 2.9e-09 ywlA S Uncharacterised protein family (UPF0715)
MFLELIEK_02017 5.8e-76
MFLELIEK_02018 2.1e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
MFLELIEK_02019 5e-17
MFLELIEK_02021 4e-87 S response regulator aspartate phosphatase
MFLELIEK_02023 3.7e-43 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
MFLELIEK_02024 5.7e-22 Q Methyltransferase
MFLELIEK_02025 3.5e-35 2.7.7.73, 2.7.7.80 H ThiF family
MFLELIEK_02026 2e-32 Q Methyltransferase domain
MFLELIEK_02027 5.5e-26 G Major Facilitator Superfamily
MFLELIEK_02028 3.4e-166 S impB/mucB/samB family C-terminal domain
MFLELIEK_02029 1.5e-46 S YolD-like protein
MFLELIEK_02030 6.3e-10
MFLELIEK_02032 1.4e-33 J Acetyltransferase (GNAT) domain
MFLELIEK_02033 4.1e-30 J Acetyltransferase (GNAT) domain
MFLELIEK_02034 5.1e-99 yokK S SMI1 / KNR4 family
MFLELIEK_02035 1.7e-73 S SMI1-KNR4 cell-wall
MFLELIEK_02036 2.8e-84 S SMI1-KNR4 cell-wall
MFLELIEK_02037 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFLELIEK_02038 9.1e-101 yokH G SMI1 / KNR4 family
MFLELIEK_02039 4.4e-277 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
MFLELIEK_02040 3.8e-54 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
MFLELIEK_02041 1e-120 yobQ K helix_turn_helix, arabinose operon control protein
MFLELIEK_02042 1e-139 yobR 2.3.1.1 J FR47-like protein
MFLELIEK_02043 2.1e-97 yobS K Transcriptional regulator
MFLELIEK_02044 4.7e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
MFLELIEK_02045 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
MFLELIEK_02046 2.5e-171 yobV K WYL domain
MFLELIEK_02047 4.1e-90 yobW
MFLELIEK_02048 1e-51 czrA K transcriptional
MFLELIEK_02049 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
MFLELIEK_02050 1.5e-92 yozB S membrane
MFLELIEK_02051 7e-144
MFLELIEK_02052 1.2e-93 yocC
MFLELIEK_02053 3.2e-186 yocD 3.4.17.13 V peptidase S66
MFLELIEK_02054 6.9e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
MFLELIEK_02055 4.6e-197 desK 2.7.13.3 T Histidine kinase
MFLELIEK_02056 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_02057 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
MFLELIEK_02058 0.0 recQ 3.6.4.12 L DNA helicase
MFLELIEK_02059 3.9e-113 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFLELIEK_02060 7.4e-83 dksA T general stress protein
MFLELIEK_02061 8.4e-54 yocL
MFLELIEK_02062 2e-30
MFLELIEK_02063 6.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
MFLELIEK_02064 1.1e-40 yozN
MFLELIEK_02065 1.9e-36 yocN
MFLELIEK_02066 4.2e-56 yozO S Bacterial PH domain
MFLELIEK_02067 2.7e-31 yozC
MFLELIEK_02068 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
MFLELIEK_02069 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
MFLELIEK_02070 8e-162 sodA 1.15.1.1 P Superoxide dismutase
MFLELIEK_02071 1.3e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
MFLELIEK_02072 5.6e-167 yocS S -transporter
MFLELIEK_02073 9.4e-191 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
MFLELIEK_02074 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
MFLELIEK_02075 0.0 yojO P Von Willebrand factor
MFLELIEK_02076 2.1e-160 yojN S ATPase family associated with various cellular activities (AAA)
MFLELIEK_02077 5e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MFLELIEK_02078 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
MFLELIEK_02079 3.1e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
MFLELIEK_02080 2.2e-108 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MFLELIEK_02082 1.6e-244 norM V Multidrug efflux pump
MFLELIEK_02083 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFLELIEK_02084 2.1e-125 yojG S deacetylase
MFLELIEK_02085 2.2e-60 yojF S Protein of unknown function (DUF1806)
MFLELIEK_02086 1.5e-43
MFLELIEK_02087 8.6e-162 rarD S -transporter
MFLELIEK_02088 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
MFLELIEK_02089 2.6e-09
MFLELIEK_02090 3.5e-127 gntP EG COG2610 H gluconate symporter and related permeases
MFLELIEK_02091 7e-61 gntP EG COG2610 H gluconate symporter and related permeases
MFLELIEK_02092 4.7e-64 yodA S tautomerase
MFLELIEK_02093 4.4e-55 yodB K transcriptional
MFLELIEK_02094 4.1e-107 yodC C nitroreductase
MFLELIEK_02095 2.1e-111 mhqD S Carboxylesterase
MFLELIEK_02096 1.2e-171 yodE E COG0346 Lactoylglutathione lyase and related lyases
MFLELIEK_02097 6.2e-28 S Protein of unknown function (DUF3311)
MFLELIEK_02098 7.3e-267 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLELIEK_02099 1.2e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MFLELIEK_02100 9.2e-127 yodH Q Methyltransferase
MFLELIEK_02101 5.2e-24 yodI
MFLELIEK_02102 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MFLELIEK_02103 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MFLELIEK_02104 5.3e-09
MFLELIEK_02105 3.6e-54 yodL S YodL-like
MFLELIEK_02106 7.8e-106 yodM 3.6.1.27 I Acid phosphatase homologues
MFLELIEK_02107 2.8e-24 yozD S YozD-like protein
MFLELIEK_02109 6e-123 yodN
MFLELIEK_02110 1.4e-36 yozE S Belongs to the UPF0346 family
MFLELIEK_02111 2.9e-47 yokU S YokU-like protein, putative antitoxin
MFLELIEK_02112 1.1e-277 kamA 5.4.3.2 E lysine 2,3-aminomutase
MFLELIEK_02113 3.3e-152 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
MFLELIEK_02114 1.3e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
MFLELIEK_02115 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFLELIEK_02116 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFLELIEK_02117 3.4e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MFLELIEK_02119 4.1e-144 yiiD K acetyltransferase
MFLELIEK_02120 2.2e-256 cgeD M maturation of the outermost layer of the spore
MFLELIEK_02121 4.5e-38 cgeC
MFLELIEK_02122 3.1e-63 cgeA
MFLELIEK_02123 2.2e-176 cgeB S Spore maturation protein
MFLELIEK_02124 4.1e-209 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
MFLELIEK_02125 8.1e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
MFLELIEK_02126 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MFLELIEK_02127 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MFLELIEK_02128 1.6e-70 ypoP K transcriptional
MFLELIEK_02129 5.8e-223 mepA V MATE efflux family protein
MFLELIEK_02130 1.6e-28 ypmT S Uncharacterized ympT
MFLELIEK_02131 4.2e-98 ypmS S protein conserved in bacteria
MFLELIEK_02132 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
MFLELIEK_02133 6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
MFLELIEK_02134 3.4e-39 ypmP S Protein of unknown function (DUF2535)
MFLELIEK_02135 9.7e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MFLELIEK_02136 1.5e-183 pspF K Transcriptional regulator
MFLELIEK_02137 2.7e-109 hlyIII S protein, Hemolysin III
MFLELIEK_02138 5.3e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
MFLELIEK_02139 8.2e-93 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MFLELIEK_02140 7.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MFLELIEK_02141 5e-113 ypjP S YpjP-like protein
MFLELIEK_02142 2.2e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
MFLELIEK_02143 3.9e-75 yphP S Belongs to the UPF0403 family
MFLELIEK_02144 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
MFLELIEK_02145 3.7e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
MFLELIEK_02146 2e-109 ypgQ S phosphohydrolase
MFLELIEK_02147 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MFLELIEK_02148 8.9e-175 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MFLELIEK_02149 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
MFLELIEK_02150 7.9e-31 cspD K Cold-shock protein
MFLELIEK_02151 3.8e-16 degR
MFLELIEK_02152 8.1e-31 S Protein of unknown function (DUF2564)
MFLELIEK_02153 3e-29 ypeQ S Zinc-finger
MFLELIEK_02154 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
MFLELIEK_02155 2.9e-105 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MFLELIEK_02156 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
MFLELIEK_02158 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
MFLELIEK_02159 2e-07
MFLELIEK_02160 8.5e-38 ypbS S Protein of unknown function (DUF2533)
MFLELIEK_02161 0.0 ypbR S Dynamin family
MFLELIEK_02162 5.1e-87 ypbQ S protein conserved in bacteria
MFLELIEK_02163 4.4e-208 bcsA Q Naringenin-chalcone synthase
MFLELIEK_02164 1.6e-228 pbuX F xanthine
MFLELIEK_02165 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MFLELIEK_02166 9.3e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
MFLELIEK_02167 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
MFLELIEK_02168 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
MFLELIEK_02169 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
MFLELIEK_02170 3.9e-187 ptxS K transcriptional
MFLELIEK_02171 1.1e-158 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MFLELIEK_02172 5.7e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_02173 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
MFLELIEK_02175 1.6e-224 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MFLELIEK_02176 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MFLELIEK_02177 3.2e-95 ypsA S Belongs to the UPF0398 family
MFLELIEK_02178 1.3e-237 yprB L RNase_H superfamily
MFLELIEK_02179 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
MFLELIEK_02180 1.1e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
MFLELIEK_02181 3.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
MFLELIEK_02182 1.2e-48 yppG S YppG-like protein
MFLELIEK_02184 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
MFLELIEK_02187 2.6e-188 yppC S Protein of unknown function (DUF2515)
MFLELIEK_02188 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MFLELIEK_02189 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
MFLELIEK_02190 4.7e-93 ypoC
MFLELIEK_02191 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MFLELIEK_02192 5.7e-129 dnaD L DNA replication protein DnaD
MFLELIEK_02193 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
MFLELIEK_02194 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MFLELIEK_02195 2.2e-79 ypmB S protein conserved in bacteria
MFLELIEK_02196 6.7e-23 ypmA S Protein of unknown function (DUF4264)
MFLELIEK_02197 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MFLELIEK_02198 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
MFLELIEK_02199 1e-156 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MFLELIEK_02200 2.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
MFLELIEK_02201 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MFLELIEK_02202 5e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MFLELIEK_02203 6.9e-209 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
MFLELIEK_02204 1.7e-128 bshB1 S proteins, LmbE homologs
MFLELIEK_02205 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
MFLELIEK_02206 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MFLELIEK_02207 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
MFLELIEK_02208 5.2e-156 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
MFLELIEK_02209 1e-142 ypjB S sporulation protein
MFLELIEK_02210 7.6e-98 ypjA S membrane
MFLELIEK_02211 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
MFLELIEK_02212 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
MFLELIEK_02213 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
MFLELIEK_02214 4.2e-77 ypiF S Protein of unknown function (DUF2487)
MFLELIEK_02215 1.1e-98 ypiB S Belongs to the UPF0302 family
MFLELIEK_02216 4.1e-234 S COG0457 FOG TPR repeat
MFLELIEK_02217 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MFLELIEK_02218 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MFLELIEK_02219 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MFLELIEK_02220 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MFLELIEK_02221 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MFLELIEK_02222 6.7e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MFLELIEK_02223 8.1e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MFLELIEK_02224 3.9e-179 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MFLELIEK_02225 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MFLELIEK_02226 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
MFLELIEK_02227 4.9e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MFLELIEK_02228 5.5e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MFLELIEK_02229 2.9e-142 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
MFLELIEK_02230 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
MFLELIEK_02231 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFLELIEK_02232 3.3e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MFLELIEK_02233 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
MFLELIEK_02234 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
MFLELIEK_02235 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
MFLELIEK_02236 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MFLELIEK_02237 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
MFLELIEK_02238 2.3e-136 yphF
MFLELIEK_02239 2e-18 yphE S Protein of unknown function (DUF2768)
MFLELIEK_02240 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MFLELIEK_02241 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MFLELIEK_02242 7.9e-28 ypzH
MFLELIEK_02243 2.5e-161 seaA S YIEGIA protein
MFLELIEK_02244 6.7e-102 yphA
MFLELIEK_02245 1e-07 S YpzI-like protein
MFLELIEK_02246 9.3e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MFLELIEK_02247 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MFLELIEK_02248 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MFLELIEK_02249 1.8e-23 S Family of unknown function (DUF5359)
MFLELIEK_02250 1.9e-110 ypfA M Flagellar protein YcgR
MFLELIEK_02251 1.4e-253 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
MFLELIEK_02252 7.5e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
MFLELIEK_02253 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
MFLELIEK_02254 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
MFLELIEK_02255 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFLELIEK_02256 2e-103 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
MFLELIEK_02257 3.4e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
MFLELIEK_02258 1.4e-80 ypbF S Protein of unknown function (DUF2663)
MFLELIEK_02259 8.2e-78 ypbE M Lysin motif
MFLELIEK_02260 1.1e-99 ypbD S metal-dependent membrane protease
MFLELIEK_02261 2.3e-284 recQ 3.6.4.12 L DNA helicase
MFLELIEK_02262 7.9e-199 ypbB 5.1.3.1 S protein conserved in bacteria
MFLELIEK_02263 4.7e-41 fer C Ferredoxin
MFLELIEK_02264 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MFLELIEK_02265 3.3e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLELIEK_02266 4.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MFLELIEK_02267 3.1e-198 rsiX
MFLELIEK_02268 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_02269 0.0 resE 2.7.13.3 T Histidine kinase
MFLELIEK_02270 6.7e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_02271 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
MFLELIEK_02272 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
MFLELIEK_02273 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
MFLELIEK_02274 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MFLELIEK_02275 1.9e-87 spmB S Spore maturation protein
MFLELIEK_02276 3.5e-103 spmA S Spore maturation protein
MFLELIEK_02277 4.7e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
MFLELIEK_02278 4e-98 ypuI S Protein of unknown function (DUF3907)
MFLELIEK_02279 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MFLELIEK_02280 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MFLELIEK_02281 1.7e-93 ypuF S Domain of unknown function (DUF309)
MFLELIEK_02282 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_02283 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MFLELIEK_02284 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MFLELIEK_02285 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
MFLELIEK_02286 4.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MFLELIEK_02287 7.8e-55 ypuD
MFLELIEK_02288 6.2e-94 sipT 3.4.21.89 U Belongs to the peptidase S26 family
MFLELIEK_02289 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
MFLELIEK_02290 7.3e-17 S SNARE associated Golgi protein
MFLELIEK_02294 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MFLELIEK_02295 8.1e-149 ypuA S Secreted protein
MFLELIEK_02296 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MFLELIEK_02297 1.4e-273 spoVAF EG Stage V sporulation protein AF
MFLELIEK_02298 1.4e-110 spoVAEA S stage V sporulation protein
MFLELIEK_02299 2.2e-57 spoVAEB S stage V sporulation protein
MFLELIEK_02300 9e-192 spoVAD I Stage V sporulation protein AD
MFLELIEK_02301 2.3e-78 spoVAC S stage V sporulation protein AC
MFLELIEK_02302 1e-67 spoVAB S Stage V sporulation protein AB
MFLELIEK_02303 9.6e-112 spoVAA S Stage V sporulation protein AA
MFLELIEK_02304 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_02305 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
MFLELIEK_02306 5e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
MFLELIEK_02307 2.4e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
MFLELIEK_02308 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
MFLELIEK_02309 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MFLELIEK_02310 2.6e-166 xerD L recombinase XerD
MFLELIEK_02311 3.7e-37 S Protein of unknown function (DUF4227)
MFLELIEK_02312 2.4e-80 fur P Belongs to the Fur family
MFLELIEK_02313 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
MFLELIEK_02314 2.1e-29 yqkK
MFLELIEK_02315 5.5e-242 mleA 1.1.1.38 C malic enzyme
MFLELIEK_02316 1.1e-227 mleN C Na H antiporter
MFLELIEK_02317 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
MFLELIEK_02318 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
MFLELIEK_02319 4.5e-58 ansR K Transcriptional regulator
MFLELIEK_02320 1.8e-220 yqxK 3.6.4.12 L DNA helicase
MFLELIEK_02321 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
MFLELIEK_02323 1.2e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
MFLELIEK_02324 3.1e-12 yqkE S Protein of unknown function (DUF3886)
MFLELIEK_02325 2.1e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
MFLELIEK_02326 9.4e-39 yqkC S Protein of unknown function (DUF2552)
MFLELIEK_02327 2.8e-54 yqkB S Belongs to the HesB IscA family
MFLELIEK_02328 9.8e-194 yqkA K GrpB protein
MFLELIEK_02329 2.6e-55 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
MFLELIEK_02330 3.6e-87 yqjY K acetyltransferase
MFLELIEK_02331 5.7e-50 S YolD-like protein
MFLELIEK_02332 1.4e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFLELIEK_02334 1.3e-224 yqjV G Major Facilitator Superfamily
MFLELIEK_02336 7.9e-72 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_02337 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MFLELIEK_02338 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MFLELIEK_02339 7.8e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_02340 3.1e-178 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
MFLELIEK_02341 1.5e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFLELIEK_02342 0.0 rocB E arginine degradation protein
MFLELIEK_02343 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
MFLELIEK_02344 6.2e-145 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
MFLELIEK_02345 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFLELIEK_02346 3.8e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MFLELIEK_02347 2e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MFLELIEK_02348 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFLELIEK_02349 5.2e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MFLELIEK_02350 6.2e-24 yqzJ
MFLELIEK_02351 1.9e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFLELIEK_02352 1.2e-137 yqjF S Uncharacterized conserved protein (COG2071)
MFLELIEK_02353 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
MFLELIEK_02354 4.5e-288 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
MFLELIEK_02355 6.6e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
MFLELIEK_02357 3e-98 yqjB S protein conserved in bacteria
MFLELIEK_02358 1.2e-172 yqjA S Putative aromatic acid exporter C-terminal domain
MFLELIEK_02359 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFLELIEK_02360 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
MFLELIEK_02361 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
MFLELIEK_02362 9.3e-77 yqiW S Belongs to the UPF0403 family
MFLELIEK_02363 3.7e-165 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
MFLELIEK_02364 3.9e-207 norA EGP Major facilitator Superfamily
MFLELIEK_02365 2.6e-152 bmrR K helix_turn_helix, mercury resistance
MFLELIEK_02366 7.2e-62 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFLELIEK_02367 5.6e-137 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MFLELIEK_02368 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
MFLELIEK_02369 7.2e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
MFLELIEK_02370 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
MFLELIEK_02371 1e-119 buk 2.7.2.7 C Belongs to the acetokinase family
MFLELIEK_02372 3.3e-59 buk 2.7.2.7 C Belongs to the acetokinase family
MFLELIEK_02373 1.1e-206 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFLELIEK_02374 2.3e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
MFLELIEK_02375 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
MFLELIEK_02376 4e-34 yqzF S Protein of unknown function (DUF2627)
MFLELIEK_02377 1.8e-09 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MFLELIEK_02378 6.3e-95 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MFLELIEK_02379 4.4e-26 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
MFLELIEK_02380 4.5e-274 prpD 4.2.1.79 S 2-methylcitrate dehydratase
MFLELIEK_02381 4.9e-207 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
MFLELIEK_02382 8.7e-75 mmgC I acyl-CoA dehydrogenase
MFLELIEK_02383 2.8e-123 mmgC I acyl-CoA dehydrogenase
MFLELIEK_02384 1.3e-154 hbdA 1.1.1.157 I Dehydrogenase
MFLELIEK_02385 1.1e-217 mmgA 2.3.1.9 I Belongs to the thiolase family
MFLELIEK_02386 7.1e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
MFLELIEK_02387 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
MFLELIEK_02388 6e-27
MFLELIEK_02389 1.8e-212 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
MFLELIEK_02391 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
MFLELIEK_02392 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
MFLELIEK_02393 1.1e-306 recN L May be involved in recombinational repair of damaged DNA
MFLELIEK_02394 1.7e-78 argR K Regulates arginine biosynthesis genes
MFLELIEK_02395 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
MFLELIEK_02396 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MFLELIEK_02397 1e-162 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MFLELIEK_02398 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFLELIEK_02399 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MFLELIEK_02400 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MFLELIEK_02401 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MFLELIEK_02402 2.1e-67 yqhY S protein conserved in bacteria
MFLELIEK_02403 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
MFLELIEK_02404 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MFLELIEK_02405 9.9e-91 spoIIIAH S SpoIIIAH-like protein
MFLELIEK_02406 2.2e-109 spoIIIAG S stage III sporulation protein AG
MFLELIEK_02407 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
MFLELIEK_02408 1.3e-197 spoIIIAE S stage III sporulation protein AE
MFLELIEK_02409 2.3e-58 spoIIIAD S Stage III sporulation protein AD
MFLELIEK_02410 7.6e-29 spoIIIAC S stage III sporulation protein AC
MFLELIEK_02411 4.1e-84 spoIIIAB S Stage III sporulation protein
MFLELIEK_02412 4e-170 spoIIIAA S stage III sporulation protein AA
MFLELIEK_02413 7.9e-37 yqhV S Protein of unknown function (DUF2619)
MFLELIEK_02414 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MFLELIEK_02415 3.4e-173 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
MFLELIEK_02416 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
MFLELIEK_02417 2.3e-93 yqhR S Conserved membrane protein YqhR
MFLELIEK_02418 8e-174 yqhQ S Protein of unknown function (DUF1385)
MFLELIEK_02419 2.2e-61 yqhP
MFLELIEK_02420 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
MFLELIEK_02421 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
MFLELIEK_02422 4.3e-138 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
MFLELIEK_02423 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
MFLELIEK_02424 1.1e-129 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFLELIEK_02425 8.3e-134 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFLELIEK_02426 1.9e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MFLELIEK_02427 3.7e-207 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
MFLELIEK_02428 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFLELIEK_02429 1.6e-151 yqhG S Bacterial protein YqhG of unknown function
MFLELIEK_02430 1.2e-24 sinI S Anti-repressor SinI
MFLELIEK_02431 1e-54 sinR K transcriptional
MFLELIEK_02432 5.6e-141 tasA S Cell division protein FtsN
MFLELIEK_02433 2.5e-58 sipW 3.4.21.89 U Signal peptidase
MFLELIEK_02434 1.1e-112 yqxM
MFLELIEK_02435 7.3e-54 yqzG S Protein of unknown function (DUF3889)
MFLELIEK_02436 4.4e-25 yqzE S YqzE-like protein
MFLELIEK_02437 8.8e-44 S ComG operon protein 7
MFLELIEK_02438 3.5e-45 comGF U Putative Competence protein ComGF
MFLELIEK_02439 9e-59 comGE
MFLELIEK_02440 2.2e-70 gspH NU protein transport across the cell outer membrane
MFLELIEK_02441 1.4e-47 comGC U Required for transformation and DNA binding
MFLELIEK_02442 5.1e-174 comGB NU COG1459 Type II secretory pathway, component PulF
MFLELIEK_02443 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MFLELIEK_02445 1.4e-173 corA P Mg2 transporter protein
MFLELIEK_02446 3.7e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFLELIEK_02447 3.2e-150 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
MFLELIEK_02449 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
MFLELIEK_02450 1.8e-37 yqgY S Protein of unknown function (DUF2626)
MFLELIEK_02451 1.8e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
MFLELIEK_02452 8.9e-23 yqgW S Protein of unknown function (DUF2759)
MFLELIEK_02453 4.5e-49 yqgV S Thiamine-binding protein
MFLELIEK_02454 7.9e-199 yqgU
MFLELIEK_02455 5.1e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
MFLELIEK_02456 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFLELIEK_02457 5.2e-181 glcK 2.7.1.2 G Glucokinase
MFLELIEK_02458 3.1e-33 yqgQ S Protein conserved in bacteria
MFLELIEK_02459 4e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
MFLELIEK_02460 2.5e-09 yqgO
MFLELIEK_02461 2.2e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MFLELIEK_02462 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MFLELIEK_02463 8.5e-199 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
MFLELIEK_02465 3.5e-50 yqzD
MFLELIEK_02466 7.3e-72 yqzC S YceG-like family
MFLELIEK_02467 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFLELIEK_02468 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MFLELIEK_02469 4.4e-158 pstA P Phosphate transport system permease
MFLELIEK_02470 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
MFLELIEK_02471 8.4e-149 pstS P Phosphate
MFLELIEK_02472 0.0 pbpA 3.4.16.4 M penicillin-binding protein
MFLELIEK_02473 9.6e-231 yqgE EGP Major facilitator superfamily
MFLELIEK_02474 8.2e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
MFLELIEK_02475 4e-73 yqgC S protein conserved in bacteria
MFLELIEK_02476 3.9e-131 yqgB S Protein of unknown function (DUF1189)
MFLELIEK_02477 5.2e-47 yqfZ M LysM domain
MFLELIEK_02478 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
MFLELIEK_02479 4.3e-62 yqfX S membrane
MFLELIEK_02480 4.6e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
MFLELIEK_02481 1.9e-77 zur P Belongs to the Fur family
MFLELIEK_02482 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
MFLELIEK_02483 2.1e-36 yqfT S Protein of unknown function (DUF2624)
MFLELIEK_02484 2.2e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MFLELIEK_02485 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MFLELIEK_02486 3.5e-12 yqfQ S YqfQ-like protein
MFLELIEK_02487 4.5e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MFLELIEK_02488 1.1e-209 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MFLELIEK_02489 1.4e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
MFLELIEK_02490 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
MFLELIEK_02491 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MFLELIEK_02492 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MFLELIEK_02493 4.5e-88 yaiI S Belongs to the UPF0178 family
MFLELIEK_02494 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MFLELIEK_02495 4.5e-112 ccpN K CBS domain
MFLELIEK_02496 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MFLELIEK_02497 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MFLELIEK_02498 6.3e-145 recO L Involved in DNA repair and RecF pathway recombination
MFLELIEK_02499 8.4e-19 S YqzL-like protein
MFLELIEK_02500 6.4e-165 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MFLELIEK_02501 2.1e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MFLELIEK_02502 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MFLELIEK_02503 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MFLELIEK_02504 0.0 yqfF S membrane-associated HD superfamily hydrolase
MFLELIEK_02506 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
MFLELIEK_02507 5.6e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
MFLELIEK_02508 2.7e-45 yqfC S sporulation protein YqfC
MFLELIEK_02509 1.3e-19 yqfB
MFLELIEK_02510 4.3e-122 yqfA S UPF0365 protein
MFLELIEK_02511 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
MFLELIEK_02512 8.3e-65 yqeY S Yqey-like protein
MFLELIEK_02513 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MFLELIEK_02514 4.1e-157 yqeW P COG1283 Na phosphate symporter
MFLELIEK_02515 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
MFLELIEK_02516 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MFLELIEK_02517 1.6e-174 prmA J Methylates ribosomal protein L11
MFLELIEK_02518 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MFLELIEK_02519 0.0 dnaK O Heat shock 70 kDa protein
MFLELIEK_02520 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MFLELIEK_02521 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MFLELIEK_02522 1.8e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
MFLELIEK_02523 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MFLELIEK_02524 1.8e-51 yqxA S Protein of unknown function (DUF3679)
MFLELIEK_02525 1.5e-222 spoIIP M stage II sporulation protein P
MFLELIEK_02526 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
MFLELIEK_02527 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
MFLELIEK_02528 9.6e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
MFLELIEK_02529 4.1e-15 S YqzM-like protein
MFLELIEK_02530 0.0 comEC S Competence protein ComEC
MFLELIEK_02531 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
MFLELIEK_02532 6.2e-103 wza L COG1555 DNA uptake protein and related DNA-binding proteins
MFLELIEK_02533 5.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MFLELIEK_02534 1.8e-136 yqeM Q Methyltransferase
MFLELIEK_02535 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MFLELIEK_02536 1.6e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
MFLELIEK_02537 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MFLELIEK_02538 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
MFLELIEK_02539 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MFLELIEK_02540 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
MFLELIEK_02541 5.3e-95 yqeG S hydrolase of the HAD superfamily
MFLELIEK_02543 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
MFLELIEK_02544 1.6e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_02545 4e-105 yqeD S SNARE associated Golgi protein
MFLELIEK_02546 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
MFLELIEK_02547 2.3e-133 yqeB
MFLELIEK_02548 2.4e-74 nucB M Deoxyribonuclease NucA/NucB
MFLELIEK_02549 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_02550 1.4e-281 cisA2 L Recombinase
MFLELIEK_02551 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MFLELIEK_02552 8.7e-182 arsB 1.20.4.1 P Arsenic resistance protein
MFLELIEK_02553 3.7e-65 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_02554 2.1e-54 arsR K ArsR family transcriptional regulator
MFLELIEK_02555 2.4e-144 yqcI S YqcI/YcgG family
MFLELIEK_02556 1.6e-96 S Tetratricopeptide repeat
MFLELIEK_02559 3.8e-277 A Pre-toxin TG
MFLELIEK_02560 2.4e-101 S Suppressor of fused protein (SUFU)
MFLELIEK_02563 5.9e-133 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MFLELIEK_02564 2.6e-68 S Bacteriophage holin family
MFLELIEK_02565 3e-159 xepA
MFLELIEK_02566 3.7e-10
MFLELIEK_02567 4.1e-56 xkdW S XkdW protein
MFLELIEK_02568 3.4e-197
MFLELIEK_02569 9e-38
MFLELIEK_02570 8.2e-97 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
MFLELIEK_02571 2.2e-185 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
MFLELIEK_02572 5e-67 xkdS S Protein of unknown function (DUF2634)
MFLELIEK_02573 1.1e-35 xkdR S Protein of unknown function (DUF2577)
MFLELIEK_02574 5.1e-176 yqbQ 3.2.1.96 G NLP P60 protein
MFLELIEK_02575 1.7e-112 xkdP S Lysin motif
MFLELIEK_02576 0.0 xkdO L Transglycosylase SLT domain
MFLELIEK_02577 6.2e-68 S Phage XkdN-like tail assembly chaperone protein, TAC
MFLELIEK_02579 3.6e-76 xkdM S Phage tail tube protein
MFLELIEK_02580 5.5e-256 xkdK S Phage tail sheath C-terminal domain
MFLELIEK_02581 3.2e-26
MFLELIEK_02582 1.4e-77
MFLELIEK_02583 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
MFLELIEK_02584 6.7e-65 yqbH S Domain of unknown function (DUF3599)
MFLELIEK_02585 2.1e-67 S Protein of unknown function (DUF3199)
MFLELIEK_02586 3.6e-51 S YqbF, hypothetical protein domain
MFLELIEK_02587 1.9e-167 xkdG S Phage capsid family
MFLELIEK_02588 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
MFLELIEK_02589 2e-115
MFLELIEK_02590 5.7e-169 S Phage Mu protein F like protein
MFLELIEK_02591 5.9e-296 yqbA S portal protein
MFLELIEK_02592 2.4e-253 S phage terminase, large subunit
MFLELIEK_02593 6.3e-107 yqaS L DNA packaging
MFLELIEK_02595 6.5e-81 L Transposase
MFLELIEK_02596 1.6e-166
MFLELIEK_02597 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
MFLELIEK_02598 7.2e-74 rusA L Endodeoxyribonuclease RusA
MFLELIEK_02600 5.9e-168 xkdC L IstB-like ATP binding protein
MFLELIEK_02601 1e-122 3.1.3.16 L DnaD domain protein
MFLELIEK_02602 2.5e-155 recT L RecT family
MFLELIEK_02603 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
MFLELIEK_02607 1.2e-103
MFLELIEK_02609 6.5e-37 K Helix-turn-helix XRE-family like proteins
MFLELIEK_02610 1.1e-56 K sequence-specific DNA binding
MFLELIEK_02612 1e-101 adk 2.7.4.3 F adenylate kinase activity
MFLELIEK_02613 4.4e-94 yqaB E IrrE N-terminal-like domain
MFLELIEK_02614 6.1e-62 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MFLELIEK_02615 1.1e-256 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFLELIEK_02616 5e-154 K Transcriptional regulator
MFLELIEK_02617 1e-66 K Glyoxalase bleomycin resistance protein dioxygenase
MFLELIEK_02619 2.6e-208 S Aspartate phosphatase response regulator
MFLELIEK_02620 3e-10 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
MFLELIEK_02621 1.5e-178 L nucleic acid phosphodiester bond hydrolysis
MFLELIEK_02622 4.8e-32 L nucleic acid phosphodiester bond hydrolysis
MFLELIEK_02624 1.9e-29 S SMI1 / KNR4 family
MFLELIEK_02625 4e-22 S SMI1-KNR4 cell-wall
MFLELIEK_02626 5.3e-46
MFLELIEK_02631 6.6e-28 S Suppressor of fused protein (SUFU)
MFLELIEK_02632 2.5e-30
MFLELIEK_02634 1.5e-21 xkdM S Phage tail tube protein
MFLELIEK_02635 2.1e-10
MFLELIEK_02642 3.1e-150 bltR K helix_turn_helix, mercury resistance
MFLELIEK_02643 3.9e-210 blt EGP Major facilitator Superfamily
MFLELIEK_02644 5.9e-82 bltD 2.3.1.57 K FR47-like protein
MFLELIEK_02645 7.9e-233 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
MFLELIEK_02646 3.9e-16 S YrzO-like protein
MFLELIEK_02647 7.3e-167 yrdR EG EamA-like transporter family
MFLELIEK_02648 3.9e-159 yrdQ K Transcriptional regulator
MFLELIEK_02649 2.5e-197 trkA P Oxidoreductase
MFLELIEK_02650 1.5e-153 czcD P COG1230 Co Zn Cd efflux system component
MFLELIEK_02651 3e-17 yodA S tautomerase
MFLELIEK_02652 2.3e-224 brnQ E Component of the transport system for branched-chain amino acids
MFLELIEK_02653 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
MFLELIEK_02654 6.2e-137 azlC E AzlC protein
MFLELIEK_02655 5.3e-78 bkdR K helix_turn_helix ASNC type
MFLELIEK_02656 2.6e-40 yrdF K ribonuclease inhibitor
MFLELIEK_02657 6.1e-227 cypA C Cytochrome P450
MFLELIEK_02658 9.1e-10 K Acetyltransferase (GNAT) family
MFLELIEK_02659 4.5e-100 yrdC 3.5.1.19 Q Isochorismatase family
MFLELIEK_02660 6.1e-56 S Protein of unknown function (DUF2568)
MFLELIEK_02662 1.4e-89 yrdA S DinB family
MFLELIEK_02663 1.2e-165 aadK G Streptomycin adenylyltransferase
MFLELIEK_02664 1.2e-191 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
MFLELIEK_02665 9.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MFLELIEK_02666 4.8e-123 yrpD S Domain of unknown function, YrpD
MFLELIEK_02668 7.6e-111 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
MFLELIEK_02669 1e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_02670 6.5e-187 yrpG C Aldo/keto reductase family
MFLELIEK_02671 7.5e-223 yraO C Citrate transporter
MFLELIEK_02672 3.7e-162 yraN K Transcriptional regulator
MFLELIEK_02673 6.5e-204 yraM S PrpF protein
MFLELIEK_02674 1.4e-150 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
MFLELIEK_02675 3.8e-41 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_02676 7.6e-149 S Alpha beta hydrolase
MFLELIEK_02677 1.7e-60 T sh3 domain protein
MFLELIEK_02678 2.4e-61 T sh3 domain protein
MFLELIEK_02679 1.3e-66 E Glyoxalase-like domain
MFLELIEK_02680 5.3e-37 yraG
MFLELIEK_02681 6.4e-63 yraF M Spore coat protein
MFLELIEK_02682 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFLELIEK_02683 7.5e-26 yraE
MFLELIEK_02684 1.1e-49 yraD M Spore coat protein
MFLELIEK_02685 1.3e-46 yraB K helix_turn_helix, mercury resistance
MFLELIEK_02686 1.6e-28 yphJ 4.1.1.44 S peroxiredoxin activity
MFLELIEK_02687 3.9e-198 adhA 1.1.1.1 C alcohol dehydrogenase
MFLELIEK_02688 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
MFLELIEK_02689 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MFLELIEK_02690 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
MFLELIEK_02691 9.9e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
MFLELIEK_02692 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
MFLELIEK_02693 1.9e-74 levD 2.7.1.202 G PTS system fructose IIA component
MFLELIEK_02694 0.0 levR K PTS system fructose IIA component
MFLELIEK_02695 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_02696 3.6e-106 yrhP E LysE type translocator
MFLELIEK_02697 5.3e-150 yrhO K Archaeal transcriptional regulator TrmB
MFLELIEK_02698 2.1e-85 sigV K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_02699 2.7e-149 rsiV S Protein of unknown function (DUF3298)
MFLELIEK_02700 0.0 yrhL I Acyltransferase family
MFLELIEK_02701 1.2e-43 yrhK S YrhK-like protein
MFLELIEK_02702 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
MFLELIEK_02703 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
MFLELIEK_02704 2.8e-91 yrhH Q methyltransferase
MFLELIEK_02707 6.7e-142 focA P Formate nitrite
MFLELIEK_02708 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
MFLELIEK_02709 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
MFLELIEK_02710 2.4e-78 yrhD S Protein of unknown function (DUF1641)
MFLELIEK_02711 4.6e-35 yrhC S YrhC-like protein
MFLELIEK_02712 7.5e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MFLELIEK_02713 8.8e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
MFLELIEK_02714 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MFLELIEK_02715 7.1e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
MFLELIEK_02716 1e-25 yrzA S Protein of unknown function (DUF2536)
MFLELIEK_02717 5.5e-63 yrrS S Protein of unknown function (DUF1510)
MFLELIEK_02718 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
MFLELIEK_02719 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MFLELIEK_02720 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MFLELIEK_02721 2.7e-246 yegQ O COG0826 Collagenase and related proteases
MFLELIEK_02722 4.3e-172 yegQ O Peptidase U32
MFLELIEK_02723 1.7e-119 yrrM 2.1.1.104 S O-methyltransferase
MFLELIEK_02724 8.2e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MFLELIEK_02725 1.2e-45 yrzB S Belongs to the UPF0473 family
MFLELIEK_02726 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MFLELIEK_02727 1.7e-41 yrzL S Belongs to the UPF0297 family
MFLELIEK_02728 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MFLELIEK_02729 7.8e-170 yrrI S AI-2E family transporter
MFLELIEK_02730 1.9e-130 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFLELIEK_02731 7.7e-141 glnH ET Belongs to the bacterial solute-binding protein 3 family
MFLELIEK_02732 2.6e-107 gluC P ABC transporter
MFLELIEK_02733 7.6e-107 glnP P ABC transporter
MFLELIEK_02735 3.7e-30 yrzR
MFLELIEK_02736 3.9e-81 yrrD S protein conserved in bacteria
MFLELIEK_02737 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MFLELIEK_02738 1.4e-15 S COG0457 FOG TPR repeat
MFLELIEK_02739 6.6e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MFLELIEK_02740 1.4e-212 iscS 2.8.1.7 E Cysteine desulfurase
MFLELIEK_02741 1.2e-70 cymR K Transcriptional regulator
MFLELIEK_02742 4.4e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
MFLELIEK_02743 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
MFLELIEK_02744 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MFLELIEK_02745 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MFLELIEK_02747 1.5e-259 lytH 3.5.1.28 M COG3103 SH3 domain protein
MFLELIEK_02748 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MFLELIEK_02749 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MFLELIEK_02750 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MFLELIEK_02751 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MFLELIEK_02752 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
MFLELIEK_02753 8.6e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
MFLELIEK_02754 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MFLELIEK_02755 9.4e-49 yrzD S Post-transcriptional regulator
MFLELIEK_02756 9.1e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_02757 1.7e-111 yrbG S membrane
MFLELIEK_02758 2.2e-73 yrzE S Protein of unknown function (DUF3792)
MFLELIEK_02759 1.1e-38 yajC U Preprotein translocase subunit YajC
MFLELIEK_02760 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MFLELIEK_02761 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MFLELIEK_02762 2.6e-18 yrzS S Protein of unknown function (DUF2905)
MFLELIEK_02763 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MFLELIEK_02764 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MFLELIEK_02765 4.8e-93 bofC S BofC C-terminal domain
MFLELIEK_02766 4.5e-252 csbX EGP Major facilitator Superfamily
MFLELIEK_02767 1.8e-192 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MFLELIEK_02768 1.2e-117 yrzF T serine threonine protein kinase
MFLELIEK_02770 2.3e-51 S Family of unknown function (DUF5412)
MFLELIEK_02771 5.3e-262 alsT E Sodium alanine symporter
MFLELIEK_02772 5.5e-127 yebC K transcriptional regulatory protein
MFLELIEK_02773 1.7e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFLELIEK_02774 3.1e-156 safA M spore coat assembly protein SafA
MFLELIEK_02775 2.7e-213 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MFLELIEK_02776 8.1e-157 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
MFLELIEK_02777 2e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
MFLELIEK_02778 9.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
MFLELIEK_02779 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
MFLELIEK_02780 8.4e-151 pheA 4.2.1.51 E Prephenate dehydratase
MFLELIEK_02781 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
MFLELIEK_02782 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MFLELIEK_02783 1.9e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
MFLELIEK_02784 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MFLELIEK_02785 4.1e-56 ysxB J ribosomal protein
MFLELIEK_02786 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MFLELIEK_02787 2e-160 spoIVFB S Stage IV sporulation protein
MFLELIEK_02788 2.5e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
MFLELIEK_02789 4.7e-143 minD D Belongs to the ParA family
MFLELIEK_02790 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MFLELIEK_02791 1.4e-84 mreD M shape-determining protein
MFLELIEK_02792 1.1e-156 mreC M Involved in formation and maintenance of cell shape
MFLELIEK_02793 1.8e-184 mreB D Rod shape-determining protein MreB
MFLELIEK_02794 5.9e-126 radC E Belongs to the UPF0758 family
MFLELIEK_02795 2.8e-102 maf D septum formation protein Maf
MFLELIEK_02796 2.7e-164 spoIIB S Sporulation related domain
MFLELIEK_02797 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
MFLELIEK_02798 9.6e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MFLELIEK_02799 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MFLELIEK_02800 1.6e-25
MFLELIEK_02801 7.8e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MFLELIEK_02802 3.3e-186 spoVID M stage VI sporulation protein D
MFLELIEK_02803 9.6e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
MFLELIEK_02804 1.1e-181 hemB 4.2.1.24 H Belongs to the ALAD family
MFLELIEK_02805 3.5e-143 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
MFLELIEK_02806 5.7e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
MFLELIEK_02807 3.6e-146 hemX O cytochrome C
MFLELIEK_02808 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
MFLELIEK_02809 5.4e-89 ysxD
MFLELIEK_02810 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
MFLELIEK_02811 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MFLELIEK_02812 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
MFLELIEK_02813 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MFLELIEK_02814 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MFLELIEK_02815 2.3e-187 ysoA H Tetratricopeptide repeat
MFLELIEK_02816 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFLELIEK_02817 2.4e-275 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MFLELIEK_02818 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
MFLELIEK_02819 1.9e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MFLELIEK_02820 9.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MFLELIEK_02821 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
MFLELIEK_02822 0.0 ilvB 2.2.1.6 E Acetolactate synthase
MFLELIEK_02824 1.5e-77 ysnE K acetyltransferase
MFLELIEK_02826 9.7e-128 ysnF S protein conserved in bacteria
MFLELIEK_02828 1.5e-91 ysnB S Phosphoesterase
MFLELIEK_02829 5e-102 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MFLELIEK_02830 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MFLELIEK_02831 3.8e-196 gerM S COG5401 Spore germination protein
MFLELIEK_02832 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MFLELIEK_02833 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_02834 3.3e-30 gerE K Transcriptional regulator
MFLELIEK_02835 1.1e-74 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
MFLELIEK_02836 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MFLELIEK_02837 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
MFLELIEK_02838 2.4e-107 sdhC C succinate dehydrogenase
MFLELIEK_02839 1.2e-79 yslB S Protein of unknown function (DUF2507)
MFLELIEK_02840 3.5e-214 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
MFLELIEK_02841 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MFLELIEK_02842 2e-52 trxA O Belongs to the thioredoxin family
MFLELIEK_02843 2.6e-304 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
MFLELIEK_02845 1.3e-176 etfA C Electron transfer flavoprotein
MFLELIEK_02846 2.2e-134 etfB C Electron transfer flavoprotein
MFLELIEK_02847 5.4e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
MFLELIEK_02848 4e-99 fadR K Transcriptional regulator
MFLELIEK_02849 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
MFLELIEK_02850 7.3e-68 yshE S membrane
MFLELIEK_02851 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MFLELIEK_02852 0.0 polX L COG1796 DNA polymerase IV (family X)
MFLELIEK_02853 3.9e-85 cvpA S membrane protein, required for colicin V production
MFLELIEK_02854 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MFLELIEK_02855 2.4e-167 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFLELIEK_02856 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFLELIEK_02857 8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MFLELIEK_02858 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MFLELIEK_02859 2.6e-32 sspI S Belongs to the SspI family
MFLELIEK_02860 6.3e-207 ysfB KT regulator
MFLELIEK_02861 6.7e-262 glcD 1.1.3.15 C Glycolate oxidase subunit
MFLELIEK_02862 2.6e-255 glcF C Glycolate oxidase
MFLELIEK_02863 1e-52 ysfE 4.4.1.5 E Glyoxalase-like domain
MFLELIEK_02864 0.0 cstA T Carbon starvation protein
MFLELIEK_02865 1e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
MFLELIEK_02866 3.4e-144 araQ G transport system permease
MFLELIEK_02867 4.2e-167 araP G carbohydrate transport
MFLELIEK_02868 2e-252 araN G carbohydrate transport
MFLELIEK_02869 1.8e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
MFLELIEK_02870 2e-146 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
MFLELIEK_02871 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
MFLELIEK_02872 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
MFLELIEK_02873 1.6e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MFLELIEK_02874 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MFLELIEK_02875 2.9e-204 ysdC G COG1363 Cellulase M and related proteins
MFLELIEK_02876 1.3e-66 ysdB S Sigma-w pathway protein YsdB
MFLELIEK_02877 7.5e-45 ysdA S Membrane
MFLELIEK_02878 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MFLELIEK_02879 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MFLELIEK_02880 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MFLELIEK_02882 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFLELIEK_02883 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
MFLELIEK_02884 5.4e-130 lytT T COG3279 Response regulator of the LytR AlgR family
MFLELIEK_02885 0.0 lytS 2.7.13.3 T Histidine kinase
MFLELIEK_02886 2.8e-148 ysaA S HAD-hyrolase-like
MFLELIEK_02887 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFLELIEK_02889 3.8e-159 ytxC S YtxC-like family
MFLELIEK_02890 4.9e-111 ytxB S SNARE associated Golgi protein
MFLELIEK_02891 3e-173 dnaI L Primosomal protein DnaI
MFLELIEK_02892 3.5e-266 dnaB L Membrane attachment protein
MFLELIEK_02893 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MFLELIEK_02894 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
MFLELIEK_02895 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFLELIEK_02896 9.9e-67 ytcD K Transcriptional regulator
MFLELIEK_02897 4.9e-205 ytbD EGP Major facilitator Superfamily
MFLELIEK_02898 8.9e-161 ytbE S reductase
MFLELIEK_02899 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MFLELIEK_02900 1.1e-107 ytaF P Probably functions as a manganese efflux pump
MFLELIEK_02901 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MFLELIEK_02902 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MFLELIEK_02903 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
MFLELIEK_02904 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_02905 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
MFLELIEK_02906 1.8e-242 icd 1.1.1.42 C isocitrate
MFLELIEK_02907 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
MFLELIEK_02908 4.7e-71 yeaL S membrane
MFLELIEK_02909 9.9e-192 ytvI S sporulation integral membrane protein YtvI
MFLELIEK_02910 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
MFLELIEK_02911 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MFLELIEK_02912 7.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MFLELIEK_02913 8.1e-182 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
MFLELIEK_02914 3.5e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MFLELIEK_02915 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
MFLELIEK_02916 0.0 dnaE 2.7.7.7 L DNA polymerase
MFLELIEK_02917 3.2e-56 ytrH S Sporulation protein YtrH
MFLELIEK_02918 2.4e-68 ytrI
MFLELIEK_02919 9.2e-29
MFLELIEK_02920 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
MFLELIEK_02921 2.4e-47 ytpI S YtpI-like protein
MFLELIEK_02922 8e-241 ytoI K transcriptional regulator containing CBS domains
MFLELIEK_02923 1.2e-158 ytnM S membrane transporter protein
MFLELIEK_02924 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
MFLELIEK_02925 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
MFLELIEK_02926 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_02927 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
MFLELIEK_02928 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_02929 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
MFLELIEK_02930 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
MFLELIEK_02931 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
MFLELIEK_02932 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
MFLELIEK_02933 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
MFLELIEK_02934 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
MFLELIEK_02935 2.9e-173 ytlI K LysR substrate binding domain
MFLELIEK_02936 1.7e-130 ytkL S Belongs to the UPF0173 family
MFLELIEK_02937 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_02939 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
MFLELIEK_02940 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MFLELIEK_02941 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MFLELIEK_02942 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MFLELIEK_02943 7e-165 ytxK 2.1.1.72 L DNA methylase
MFLELIEK_02944 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MFLELIEK_02945 8.7e-70 ytfJ S Sporulation protein YtfJ
MFLELIEK_02946 5.6e-116 ytfI S Protein of unknown function (DUF2953)
MFLELIEK_02947 1.3e-87 yteJ S RDD family
MFLELIEK_02948 7.1e-181 sppA OU signal peptide peptidase SppA
MFLELIEK_02949 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MFLELIEK_02950 0.0 ytcJ S amidohydrolase
MFLELIEK_02951 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFLELIEK_02952 2e-29 sspB S spore protein
MFLELIEK_02953 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MFLELIEK_02954 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
MFLELIEK_02955 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
MFLELIEK_02956 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MFLELIEK_02957 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
MFLELIEK_02958 3.4e-109 yttP K Transcriptional regulator
MFLELIEK_02959 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
MFLELIEK_02960 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
MFLELIEK_02961 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MFLELIEK_02963 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFLELIEK_02964 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
MFLELIEK_02965 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
MFLELIEK_02966 4.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
MFLELIEK_02967 6.1e-224 acuC BQ histone deacetylase
MFLELIEK_02968 5.2e-125 motS N Flagellar motor protein
MFLELIEK_02969 6e-146 motA N flagellar motor
MFLELIEK_02970 3.8e-182 ccpA K catabolite control protein A
MFLELIEK_02971 1.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
MFLELIEK_02972 7e-53 ytxJ O Protein of unknown function (DUF2847)
MFLELIEK_02973 6.6e-17 ytxH S COG4980 Gas vesicle protein
MFLELIEK_02974 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MFLELIEK_02975 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MFLELIEK_02976 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MFLELIEK_02977 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MFLELIEK_02978 9.8e-149 ytpQ S Belongs to the UPF0354 family
MFLELIEK_02979 4.6e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MFLELIEK_02980 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
MFLELIEK_02981 1.4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
MFLELIEK_02982 2.2e-51 ytzB S small secreted protein
MFLELIEK_02983 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
MFLELIEK_02984 1.8e-148 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
MFLELIEK_02985 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MFLELIEK_02986 2e-45 ytzH S YtzH-like protein
MFLELIEK_02987 1e-150 ytmP 2.7.1.89 M Phosphotransferase
MFLELIEK_02988 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
MFLELIEK_02989 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MFLELIEK_02990 1.3e-165 ytlQ
MFLELIEK_02991 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
MFLELIEK_02992 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MFLELIEK_02993 7.1e-272 pepV 3.5.1.18 E Dipeptidase
MFLELIEK_02994 7.2e-226 pbuO S permease
MFLELIEK_02995 1.5e-203 ythQ U Bacterial ABC transporter protein EcsB
MFLELIEK_02996 9e-130 ythP V ABC transporter
MFLELIEK_02997 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
MFLELIEK_02998 1.8e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MFLELIEK_02999 3.6e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_03000 1.4e-231 ytfP S HI0933-like protein
MFLELIEK_03001 9.9e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
MFLELIEK_03002 3.1e-26 yteV S Sporulation protein Cse60
MFLELIEK_03003 4.8e-117 yteU S Integral membrane protein
MFLELIEK_03004 9.2e-258 yteT S Oxidoreductase family, C-terminal alpha/beta domain
MFLELIEK_03005 4.6e-73 yteS G transport
MFLELIEK_03006 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
MFLELIEK_03007 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
MFLELIEK_03008 0.0 ytdP K Transcriptional regulator
MFLELIEK_03009 1.5e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
MFLELIEK_03010 1.3e-149 ytcP G COG0395 ABC-type sugar transport system, permease component
MFLELIEK_03011 9e-136 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
MFLELIEK_03012 1.8e-223 bioI 1.14.14.46 C Cytochrome P450
MFLELIEK_03013 8.4e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MFLELIEK_03014 3.8e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MFLELIEK_03015 1.1e-217 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
MFLELIEK_03016 1.1e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
MFLELIEK_03017 5.2e-141 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
MFLELIEK_03018 5.4e-172 ytaP S Acetyl xylan esterase (AXE1)
MFLELIEK_03019 4.3e-189 msmR K Transcriptional regulator
MFLELIEK_03020 1.5e-244 msmE G Bacterial extracellular solute-binding protein
MFLELIEK_03021 1.5e-166 amyD P ABC transporter
MFLELIEK_03022 4.4e-144 amyC P ABC transporter (permease)
MFLELIEK_03023 2.6e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
MFLELIEK_03024 8.1e-51 ytwF P Sulfurtransferase
MFLELIEK_03025 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MFLELIEK_03026 7.7e-55 ytvB S Protein of unknown function (DUF4257)
MFLELIEK_03027 1.5e-141 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
MFLELIEK_03028 1.5e-209 yttB EGP Major facilitator Superfamily
MFLELIEK_03029 8.7e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MFLELIEK_03030 0.0 bceB V ABC transporter (permease)
MFLELIEK_03031 1.1e-138 bceA V ABC transporter, ATP-binding protein
MFLELIEK_03032 1.8e-184 T PhoQ Sensor
MFLELIEK_03033 1.1e-129 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_03034 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFLELIEK_03035 3.1e-127 ytrE V ABC transporter, ATP-binding protein
MFLELIEK_03036 5.9e-148
MFLELIEK_03037 8.3e-166 P ABC-2 family transporter protein
MFLELIEK_03038 4.2e-161 ytrB P abc transporter atp-binding protein
MFLELIEK_03039 5.1e-66 ytrA K GntR family transcriptional regulator
MFLELIEK_03041 6.7e-41 ytzC S Protein of unknown function (DUF2524)
MFLELIEK_03042 2.1e-190 yhcC S Fe-S oxidoreductase
MFLELIEK_03043 3.3e-106 ytqB J Putative rRNA methylase
MFLELIEK_03044 7.5e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
MFLELIEK_03045 5.5e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
MFLELIEK_03046 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MFLELIEK_03047 1.1e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_03048 0.0 asnB 6.3.5.4 E Asparagine synthase
MFLELIEK_03049 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MFLELIEK_03050 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
MFLELIEK_03051 1.2e-38 ytmB S Protein of unknown function (DUF2584)
MFLELIEK_03052 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
MFLELIEK_03053 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
MFLELIEK_03054 1.4e-144 ytlC P ABC transporter
MFLELIEK_03055 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
MFLELIEK_03056 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
MFLELIEK_03057 5.4e-63 ytkC S Bacteriophage holin family
MFLELIEK_03058 2.1e-76 dps P Belongs to the Dps family
MFLELIEK_03060 2.4e-72 ytkA S YtkA-like
MFLELIEK_03061 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MFLELIEK_03062 9.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MFLELIEK_03063 3.6e-41 rpmE2 J Ribosomal protein L31
MFLELIEK_03064 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
MFLELIEK_03065 1.8e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
MFLELIEK_03066 1.1e-24 S Domain of Unknown Function (DUF1540)
MFLELIEK_03067 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
MFLELIEK_03068 8.8e-232 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
MFLELIEK_03069 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
MFLELIEK_03070 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
MFLELIEK_03071 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MFLELIEK_03072 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MFLELIEK_03073 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MFLELIEK_03074 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
MFLELIEK_03075 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
MFLELIEK_03076 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
MFLELIEK_03077 2.6e-132 dksA T COG1734 DnaK suppressor protein
MFLELIEK_03078 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
MFLELIEK_03079 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFLELIEK_03080 1.1e-180 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
MFLELIEK_03081 3.6e-235 ytcC M Glycosyltransferase Family 4
MFLELIEK_03083 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
MFLELIEK_03084 2.6e-216 cotSA M Glycosyl transferases group 1
MFLELIEK_03085 2.8e-204 cotI S Spore coat protein
MFLELIEK_03086 9.9e-77 tspO T membrane
MFLELIEK_03087 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MFLELIEK_03088 4.8e-287 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
MFLELIEK_03089 1.3e-124 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
MFLELIEK_03090 2.6e-195 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MFLELIEK_03091 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MFLELIEK_03100 7.8e-08
MFLELIEK_03101 1.3e-09
MFLELIEK_03108 2e-08
MFLELIEK_03113 3.4e-39 S COG NOG14552 non supervised orthologous group
MFLELIEK_03114 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
MFLELIEK_03115 3.4e-94 M1-753 M FR47-like protein
MFLELIEK_03116 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
MFLELIEK_03117 1.6e-75 yuaF OU Membrane protein implicated in regulation of membrane protease activity
MFLELIEK_03118 3.9e-84 yuaE S DinB superfamily
MFLELIEK_03119 1.1e-106 yuaD
MFLELIEK_03120 3.2e-228 gbsB 1.1.1.1 C alcohol dehydrogenase
MFLELIEK_03121 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
MFLELIEK_03122 2.7e-94 yuaC K Belongs to the GbsR family
MFLELIEK_03123 2.2e-91 yuaB
MFLELIEK_03124 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
MFLELIEK_03125 1.6e-236 ktrB P Potassium
MFLELIEK_03126 1e-38 yiaA S yiaA/B two helix domain
MFLELIEK_03127 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFLELIEK_03128 6.4e-274 yubD P Major Facilitator Superfamily
MFLELIEK_03129 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
MFLELIEK_03131 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MFLELIEK_03132 1.3e-194 yubA S transporter activity
MFLELIEK_03133 3.3e-183 ygjR S Oxidoreductase
MFLELIEK_03134 2.8e-251 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
MFLELIEK_03135 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
MFLELIEK_03136 3.6e-274 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
MFLELIEK_03137 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
MFLELIEK_03138 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
MFLELIEK_03140 2.1e-237 mcpA NT chemotaxis protein
MFLELIEK_03141 2.5e-294 mcpA NT chemotaxis protein
MFLELIEK_03142 6.9e-220 mcpA NT chemotaxis protein
MFLELIEK_03143 3.5e-224 mcpA NT chemotaxis protein
MFLELIEK_03144 8.4e-139 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
MFLELIEK_03145 1e-35
MFLELIEK_03146 3.1e-71 yugU S Uncharacterised protein family UPF0047
MFLELIEK_03147 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
MFLELIEK_03148 8.4e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
MFLELIEK_03149 1.4e-116 yugP S Zn-dependent protease
MFLELIEK_03150 2.3e-38
MFLELIEK_03151 1.1e-53 mstX S Membrane-integrating protein Mistic
MFLELIEK_03152 3.1e-181 yugO P COG1226 Kef-type K transport systems
MFLELIEK_03153 1.3e-72 yugN S YugN-like family
MFLELIEK_03155 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
MFLELIEK_03156 2.4e-228 yugK C Dehydrogenase
MFLELIEK_03157 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
MFLELIEK_03158 1.1e-34 yuzA S Domain of unknown function (DUF378)
MFLELIEK_03159 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
MFLELIEK_03160 2.1e-199 yugH 2.6.1.1 E Aminotransferase
MFLELIEK_03161 1.6e-85 alaR K Transcriptional regulator
MFLELIEK_03162 4.9e-156 yugF I Hydrolase
MFLELIEK_03163 4.6e-39 yugE S Domain of unknown function (DUF1871)
MFLELIEK_03164 6.4e-226 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
MFLELIEK_03165 4.6e-233 T PhoQ Sensor
MFLELIEK_03166 2.2e-69 kapB G Kinase associated protein B
MFLELIEK_03167 4.2e-115 kapD L the KinA pathway to sporulation
MFLELIEK_03169 3.8e-185 yuxJ EGP Major facilitator Superfamily
MFLELIEK_03170 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
MFLELIEK_03171 2e-73 yuxK S protein conserved in bacteria
MFLELIEK_03172 1.8e-77 yufK S Family of unknown function (DUF5366)
MFLELIEK_03173 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
MFLELIEK_03174 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
MFLELIEK_03175 4.2e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
MFLELIEK_03176 3.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
MFLELIEK_03177 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
MFLELIEK_03178 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
MFLELIEK_03179 1.3e-233 maeN C COG3493 Na citrate symporter
MFLELIEK_03180 3.2e-14
MFLELIEK_03181 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
MFLELIEK_03182 3.5e-68 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFLELIEK_03183 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFLELIEK_03184 6.4e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFLELIEK_03185 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFLELIEK_03186 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
MFLELIEK_03187 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
MFLELIEK_03188 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
MFLELIEK_03189 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_03190 7.1e-269 comP 2.7.13.3 T Histidine kinase
MFLELIEK_03192 1.4e-141 comQ H Belongs to the FPP GGPP synthase family
MFLELIEK_03194 3.8e-23 yuzC
MFLELIEK_03195 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
MFLELIEK_03196 1e-265 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MFLELIEK_03197 2.8e-102 pncA Q COG1335 Amidases related to nicotinamidase
MFLELIEK_03198 7.9e-67 yueI S Protein of unknown function (DUF1694)
MFLELIEK_03199 2.8e-38 yueH S YueH-like protein
MFLELIEK_03200 2.1e-32 yueG S Spore germination protein gerPA/gerPF
MFLELIEK_03201 1.9e-190 yueF S transporter activity
MFLELIEK_03202 6.1e-72 S Protein of unknown function (DUF2283)
MFLELIEK_03203 4.8e-96 yueE S phosphohydrolase
MFLELIEK_03204 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_03205 6.6e-65 yueC S Family of unknown function (DUF5383)
MFLELIEK_03206 0.0 esaA S type VII secretion protein EsaA
MFLELIEK_03207 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
MFLELIEK_03208 2.4e-208 essB S WXG100 protein secretion system (Wss), protein YukC
MFLELIEK_03209 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
MFLELIEK_03210 2.8e-45 esxA S Belongs to the WXG100 family
MFLELIEK_03211 4.2e-228 yukF QT Transcriptional regulator
MFLELIEK_03212 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
MFLELIEK_03213 3.5e-131 yukJ S Uncharacterized conserved protein (DUF2278)
MFLELIEK_03214 5e-36 mbtH S MbtH-like protein
MFLELIEK_03215 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_03216 2.6e-177 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
MFLELIEK_03217 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
MFLELIEK_03218 1.5e-225 entC 5.4.4.2 HQ Isochorismate synthase
MFLELIEK_03219 3.6e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03220 1.5e-166 besA S Putative esterase
MFLELIEK_03221 1.7e-121 yuiH S Oxidoreductase molybdopterin binding domain
MFLELIEK_03222 2e-93 bioY S Biotin biosynthesis protein
MFLELIEK_03223 3.9e-211 yuiF S antiporter
MFLELIEK_03224 7.1e-278 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MFLELIEK_03225 1.2e-77 yuiD S protein conserved in bacteria
MFLELIEK_03226 4.4e-115 yuiC S protein conserved in bacteria
MFLELIEK_03227 7.1e-26 yuiB S Putative membrane protein
MFLELIEK_03228 4.2e-236 yumB 1.6.99.3 C NADH dehydrogenase
MFLELIEK_03229 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
MFLELIEK_03231 1e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MFLELIEK_03232 1.9e-115 paiB K Putative FMN-binding domain
MFLELIEK_03233 1.8e-71 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_03235 3.7e-63 erpA S Belongs to the HesB IscA family
MFLELIEK_03236 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MFLELIEK_03237 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFLELIEK_03238 3.2e-39 yuzB S Belongs to the UPF0349 family
MFLELIEK_03239 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
MFLELIEK_03240 3.5e-57 yuzD S protein conserved in bacteria
MFLELIEK_03241 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
MFLELIEK_03242 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
MFLELIEK_03243 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MFLELIEK_03244 2e-197 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MFLELIEK_03245 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
MFLELIEK_03246 2.9e-198 yutH S Spore coat protein
MFLELIEK_03247 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
MFLELIEK_03248 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MFLELIEK_03249 8.6e-75 yutE S Protein of unknown function DUF86
MFLELIEK_03250 9.7e-48 yutD S protein conserved in bacteria
MFLELIEK_03251 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
MFLELIEK_03252 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MFLELIEK_03253 3.8e-195 lytH M Peptidase, M23
MFLELIEK_03254 4.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
MFLELIEK_03255 5.3e-47 yunC S Domain of unknown function (DUF1805)
MFLELIEK_03256 4.9e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MFLELIEK_03257 1e-140 yunE S membrane transporter protein
MFLELIEK_03258 7.3e-171 yunF S Protein of unknown function DUF72
MFLELIEK_03259 6.7e-62 yunG
MFLELIEK_03260 7.3e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
MFLELIEK_03261 3.4e-302 pucR QT COG2508 Regulator of polyketide synthase expression
MFLELIEK_03262 2.1e-236 pbuX F Permease family
MFLELIEK_03263 1.3e-222 pbuX F xanthine
MFLELIEK_03264 7.3e-283 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
MFLELIEK_03265 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
MFLELIEK_03266 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
MFLELIEK_03267 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
MFLELIEK_03268 6.6e-148 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
MFLELIEK_03269 2.2e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
MFLELIEK_03270 6.8e-184 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MFLELIEK_03271 2.5e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
MFLELIEK_03272 9.8e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
MFLELIEK_03273 2.7e-168 bsn L Ribonuclease
MFLELIEK_03274 2.9e-204 msmX P Belongs to the ABC transporter superfamily
MFLELIEK_03275 1.1e-135 yurK K UTRA
MFLELIEK_03276 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
MFLELIEK_03277 1.6e-168 yurM P COG0395 ABC-type sugar transport system, permease component
MFLELIEK_03278 5.3e-156 yurN G Binding-protein-dependent transport system inner membrane component
MFLELIEK_03279 5.5e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
MFLELIEK_03280 2.6e-183 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
MFLELIEK_03281 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
MFLELIEK_03282 6.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
MFLELIEK_03284 1e-41
MFLELIEK_03285 2.4e-65 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_03286 3.5e-271 sufB O FeS cluster assembly
MFLELIEK_03287 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
MFLELIEK_03288 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MFLELIEK_03289 9.1e-245 sufD O assembly protein SufD
MFLELIEK_03290 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
MFLELIEK_03291 2.4e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MFLELIEK_03292 9.4e-147 metQ P Belongs to the NlpA lipoprotein family
MFLELIEK_03293 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
MFLELIEK_03294 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MFLELIEK_03295 2.4e-56 yusD S SCP-2 sterol transfer family
MFLELIEK_03296 5.6e-55 traF CO Thioredoxin
MFLELIEK_03297 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
MFLELIEK_03298 1.1e-39 yusG S Protein of unknown function (DUF2553)
MFLELIEK_03299 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
MFLELIEK_03300 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
MFLELIEK_03301 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
MFLELIEK_03302 1.4e-217 fadA 2.3.1.16 I Belongs to the thiolase family
MFLELIEK_03303 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
MFLELIEK_03304 8.1e-09 S YuzL-like protein
MFLELIEK_03305 1.9e-164 fadM E Proline dehydrogenase
MFLELIEK_03306 5.1e-40
MFLELIEK_03307 5.4e-53 yusN M Coat F domain
MFLELIEK_03308 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
MFLELIEK_03309 9.4e-292 yusP P Major facilitator superfamily
MFLELIEK_03310 2.7e-64 yusQ S Tautomerase enzyme
MFLELIEK_03311 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03312 2.2e-157 yusT K LysR substrate binding domain
MFLELIEK_03313 3.8e-47 yusU S Protein of unknown function (DUF2573)
MFLELIEK_03314 1e-153 yusV 3.6.3.34 HP ABC transporter
MFLELIEK_03315 1.9e-66 S YusW-like protein
MFLELIEK_03316 2.1e-300 pepF2 E COG1164 Oligoendopeptidase F
MFLELIEK_03317 2.9e-151 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03318 1.2e-79 dps P Ferritin-like domain
MFLELIEK_03319 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFLELIEK_03320 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_03321 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
MFLELIEK_03322 4.3e-158 yuxN K Transcriptional regulator
MFLELIEK_03323 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MFLELIEK_03324 2.3e-24 S Protein of unknown function (DUF3970)
MFLELIEK_03325 3.7e-247 gerAA EG Spore germination protein
MFLELIEK_03326 2e-197 gerAB E Spore germination protein
MFLELIEK_03327 1.9e-187 gerAC S Spore germination B3/ GerAC like, C-terminal
MFLELIEK_03328 8.6e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_03329 1.6e-186 vraS 2.7.13.3 T Histidine kinase
MFLELIEK_03330 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MFLELIEK_03331 4.5e-123 liaG S Putative adhesin
MFLELIEK_03332 2.6e-102 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
MFLELIEK_03333 1.4e-60 liaI S membrane
MFLELIEK_03334 4.8e-227 yvqJ EGP Major facilitator Superfamily
MFLELIEK_03335 1.4e-99 yvqK 2.5.1.17 S Adenosyltransferase
MFLELIEK_03336 4.1e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
MFLELIEK_03337 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_03338 6.5e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
MFLELIEK_03339 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03340 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
MFLELIEK_03341 0.0 T PhoQ Sensor
MFLELIEK_03342 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_03343 7.2e-23
MFLELIEK_03344 9.5e-98 yvrI K RNA polymerase
MFLELIEK_03345 2.4e-19 S YvrJ protein family
MFLELIEK_03346 3.6e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
MFLELIEK_03347 1.3e-64 yvrL S Regulatory protein YrvL
MFLELIEK_03348 1e-208 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
MFLELIEK_03349 7.9e-123 macB V ABC transporter, ATP-binding protein
MFLELIEK_03350 9e-175 M Efflux transporter rnd family, mfp subunit
MFLELIEK_03351 2.9e-148 fhuC 3.6.3.34 HP ABC transporter
MFLELIEK_03352 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_03353 1.1e-181 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MFLELIEK_03354 7.6e-177 fhuD P ABC transporter
MFLELIEK_03355 1.8e-235 yvsH E Arginine ornithine antiporter
MFLELIEK_03356 6.5e-16 S Small spore protein J (Spore_SspJ)
MFLELIEK_03357 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
MFLELIEK_03358 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
MFLELIEK_03359 2.4e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
MFLELIEK_03360 1.6e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
MFLELIEK_03361 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
MFLELIEK_03362 1.1e-155 yvgN S reductase
MFLELIEK_03363 2.1e-85 yvgO
MFLELIEK_03364 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
MFLELIEK_03365 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
MFLELIEK_03366 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MFLELIEK_03367 0.0 helD 3.6.4.12 L DNA helicase
MFLELIEK_03369 1.6e-106 yvgT S membrane
MFLELIEK_03370 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
MFLELIEK_03371 2.7e-104 bdbD O Thioredoxin
MFLELIEK_03372 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
MFLELIEK_03373 0.0 copA 3.6.3.54 P P-type ATPase
MFLELIEK_03374 5.9e-29 copZ P Copper resistance protein CopZ
MFLELIEK_03375 2.2e-48 csoR S transcriptional
MFLELIEK_03376 1.2e-194 yvaA 1.1.1.371 S Oxidoreductase
MFLELIEK_03377 7e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MFLELIEK_03378 0.0 yvaC S Fusaric acid resistance protein-like
MFLELIEK_03379 9.7e-73 yvaD S Family of unknown function (DUF5360)
MFLELIEK_03380 1.8e-54 yvaE P Small Multidrug Resistance protein
MFLELIEK_03381 8.6e-99 K Bacterial regulatory proteins, tetR family
MFLELIEK_03382 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03384 3.6e-12
MFLELIEK_03385 2.1e-179 A Pre-toxin TG
MFLELIEK_03386 2.4e-07 S Immunity protein 50
MFLELIEK_03388 1.2e-110 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_03389 1.8e-56 S Bacteriophage holin family
MFLELIEK_03391 3.7e-16
MFLELIEK_03392 1.1e-193 S Domain of unknown function (DUF2479)
MFLELIEK_03393 3.2e-257
MFLELIEK_03394 4.2e-242 NU Prophage endopeptidase tail
MFLELIEK_03395 2.2e-111 S Phage tail protein
MFLELIEK_03396 0.0 S peptidoglycan catabolic process
MFLELIEK_03397 4.8e-10
MFLELIEK_03398 2e-26
MFLELIEK_03399 1.5e-61
MFLELIEK_03400 1.9e-30
MFLELIEK_03401 2.3e-47 S Bacteriophage HK97-gp10, putative tail-component
MFLELIEK_03402 1.1e-24 S Phage gp6-like head-tail connector protein
MFLELIEK_03403 1.3e-26 S peptidoglycan catabolic process
MFLELIEK_03405 2.9e-181 S capsid protein
MFLELIEK_03406 1e-105 S peptidase activity
MFLELIEK_03407 2.7e-214 S Phage portal protein
MFLELIEK_03408 2.2e-10
MFLELIEK_03409 2e-220 S Phage Terminase
MFLELIEK_03410 4.6e-70 S Phage terminase, small subunit
MFLELIEK_03411 3.8e-08
MFLELIEK_03412 2.2e-59 S HNH endonuclease
MFLELIEK_03414 9.7e-21
MFLELIEK_03415 2.3e-15 S PIN domain
MFLELIEK_03416 2.6e-73 L Phage integrase family
MFLELIEK_03417 9.6e-53 wecC 1.1.1.336 M ArpU family transcriptional regulator
MFLELIEK_03419 3.8e-11 S YopX protein
MFLELIEK_03421 1.5e-46 S dUTPase
MFLELIEK_03423 6.9e-26
MFLELIEK_03426 2e-07 yqaO S Phage-like element PBSX protein XtrA
MFLELIEK_03430 1.9e-31
MFLELIEK_03431 2e-43 dnaC L IstB-like ATP binding protein
MFLELIEK_03432 9e-71 ybl78 L Conserved phage C-terminus (Phg_2220_C)
MFLELIEK_03434 8.6e-11 S sequence-specific DNA binding
MFLELIEK_03435 3.6e-07 acoR T PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase
MFLELIEK_03436 2.5e-44 K Helix-turn-helix XRE-family like proteins
MFLELIEK_03439 4e-60
MFLELIEK_03440 7.6e-125 S Phage integrase family
MFLELIEK_03442 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MFLELIEK_03443 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MFLELIEK_03444 5.6e-143 est 3.1.1.1 S Carboxylesterase
MFLELIEK_03445 2.4e-23 secG U Preprotein translocase subunit SecG
MFLELIEK_03446 1.3e-150 yvaM S Serine aminopeptidase, S33
MFLELIEK_03447 7.5e-36 yvzC K Transcriptional
MFLELIEK_03448 4e-69 K transcriptional
MFLELIEK_03449 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
MFLELIEK_03450 2.2e-54 yodB K transcriptional
MFLELIEK_03451 3e-216 NT chemotaxis protein
MFLELIEK_03452 5.2e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFLELIEK_03453 6.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFLELIEK_03454 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFLELIEK_03455 9.8e-211 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFLELIEK_03456 2.1e-62 yvbF K Belongs to the GbsR family
MFLELIEK_03457 4.3e-105 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFLELIEK_03458 2.1e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MFLELIEK_03459 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
MFLELIEK_03460 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
MFLELIEK_03461 1.3e-96 yvbF K Belongs to the GbsR family
MFLELIEK_03462 6.4e-103 yvbG U UPF0056 membrane protein
MFLELIEK_03463 1.9e-112 yvbH S YvbH-like oligomerisation region
MFLELIEK_03464 2.3e-122 exoY M Membrane
MFLELIEK_03465 0.0 tcaA S response to antibiotic
MFLELIEK_03466 1.7e-81 yvbK 3.1.3.25 K acetyltransferase
MFLELIEK_03467 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MFLELIEK_03468 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
MFLELIEK_03469 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MFLELIEK_03470 1.1e-217 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MFLELIEK_03471 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MFLELIEK_03472 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFLELIEK_03473 2.1e-252 araE EGP Major facilitator Superfamily
MFLELIEK_03474 5.5e-203 araR K transcriptional
MFLELIEK_03475 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_03476 1.6e-157 yvbU K Transcriptional regulator
MFLELIEK_03477 7.2e-156 yvbV EG EamA-like transporter family
MFLELIEK_03478 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
MFLELIEK_03479 6.8e-195 yvbX S Glycosyl hydrolase
MFLELIEK_03480 1.2e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFLELIEK_03481 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
MFLELIEK_03482 1e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
MFLELIEK_03483 1.3e-44 S Protein of unknown function (DUF2812)
MFLELIEK_03484 2.6e-31 K Transcriptional regulator PadR-like family
MFLELIEK_03485 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_03486 3.9e-196 desK 2.7.13.3 T Histidine kinase
MFLELIEK_03487 4e-133 yvfS V COG0842 ABC-type multidrug transport system, permease component
MFLELIEK_03488 2.6e-158 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
MFLELIEK_03490 6.4e-156 rsbQ S Alpha/beta hydrolase family
MFLELIEK_03491 1.8e-199 rsbU 3.1.3.3 T response regulator
MFLELIEK_03492 2.4e-250 galA 3.2.1.89 G arabinogalactan
MFLELIEK_03493 0.0 lacA 3.2.1.23 G beta-galactosidase
MFLELIEK_03494 7.2e-150 ganQ P transport
MFLELIEK_03495 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
MFLELIEK_03496 1e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
MFLELIEK_03497 2e-183 lacR K Transcriptional regulator
MFLELIEK_03498 2.3e-112 yvfI K COG2186 Transcriptional regulators
MFLELIEK_03499 3.3e-308 yvfH C L-lactate permease
MFLELIEK_03500 6.7e-240 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
MFLELIEK_03501 1e-31 yvfG S YvfG protein
MFLELIEK_03502 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
MFLELIEK_03503 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
MFLELIEK_03504 9e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
MFLELIEK_03505 1.2e-106 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFLELIEK_03506 8.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_03507 2.7e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
MFLELIEK_03508 1.2e-202 epsI GM pyruvyl transferase
MFLELIEK_03509 2e-194 epsH GT2 S Glycosyltransferase like family 2
MFLELIEK_03510 1.8e-206 epsG S EpsG family
MFLELIEK_03511 6.4e-218 epsF GT4 M Glycosyl transferases group 1
MFLELIEK_03512 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MFLELIEK_03513 3.8e-223 epsD GT4 M Glycosyl transferase 4-like
MFLELIEK_03514 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
MFLELIEK_03515 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
MFLELIEK_03516 4e-122 ywqC M biosynthesis protein
MFLELIEK_03517 6.3e-76 slr K transcriptional
MFLELIEK_03518 2.7e-282 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
MFLELIEK_03520 5.1e-92 padC Q Phenolic acid decarboxylase
MFLELIEK_03521 3.8e-73 MA20_18690 S Protein of unknown function (DUF3237)
MFLELIEK_03522 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MFLELIEK_03523 3.2e-261 pbpE V Beta-lactamase
MFLELIEK_03524 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
MFLELIEK_03525 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
MFLELIEK_03526 1.8e-295 yveA E amino acid
MFLELIEK_03527 2.8e-105 yvdT K Transcriptional regulator
MFLELIEK_03528 1.9e-50 ykkC P Small Multidrug Resistance protein
MFLELIEK_03529 4.1e-50 sugE P Small Multidrug Resistance protein
MFLELIEK_03530 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
MFLELIEK_03532 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MFLELIEK_03533 1.3e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MFLELIEK_03534 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
MFLELIEK_03535 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
MFLELIEK_03536 3.1e-156 malA S Protein of unknown function (DUF1189)
MFLELIEK_03537 8.6e-148 malD P transport
MFLELIEK_03538 2.1e-241 malC P COG1175 ABC-type sugar transport systems, permease components
MFLELIEK_03539 3.4e-233 mdxE G COG2182 Maltose-binding periplasmic proteins domains
MFLELIEK_03540 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
MFLELIEK_03541 2.6e-172 yvdE K Transcriptional regulator
MFLELIEK_03542 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MFLELIEK_03543 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
MFLELIEK_03544 6.2e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
MFLELIEK_03545 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
MFLELIEK_03546 5.6e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MFLELIEK_03547 0.0 yxdM V ABC transporter (permease)
MFLELIEK_03548 5.6e-141 yvcR V ABC transporter, ATP-binding protein
MFLELIEK_03549 5.8e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MFLELIEK_03550 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_03551 8.8e-33
MFLELIEK_03552 4.9e-142 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
MFLELIEK_03553 1.6e-36 crh G Phosphocarrier protein Chr
MFLELIEK_03554 1.4e-170 whiA K May be required for sporulation
MFLELIEK_03555 2.1e-177 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MFLELIEK_03556 5.7e-166 rapZ S Displays ATPase and GTPase activities
MFLELIEK_03557 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
MFLELIEK_03558 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MFLELIEK_03559 2.8e-98 usp CBM50 M protein conserved in bacteria
MFLELIEK_03560 8.4e-276 S COG0457 FOG TPR repeat
MFLELIEK_03561 0.0 msbA2 3.6.3.44 V ABC transporter
MFLELIEK_03563 0.0
MFLELIEK_03564 2.2e-75
MFLELIEK_03565 2.3e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
MFLELIEK_03566 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MFLELIEK_03567 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MFLELIEK_03568 7.3e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MFLELIEK_03569 4.7e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MFLELIEK_03570 5.8e-228 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MFLELIEK_03571 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MFLELIEK_03572 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MFLELIEK_03573 4.5e-140 yvpB NU protein conserved in bacteria
MFLELIEK_03574 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
MFLELIEK_03575 9.6e-81 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
MFLELIEK_03576 1.1e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
MFLELIEK_03577 1.6e-163 yvoD P COG0370 Fe2 transport system protein B
MFLELIEK_03578 3.2e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MFLELIEK_03579 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MFLELIEK_03580 1.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MFLELIEK_03581 3.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MFLELIEK_03582 3.6e-134 yvoA K transcriptional
MFLELIEK_03583 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
MFLELIEK_03584 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_03585 5.3e-231 cypX 1.14.15.13 C Cytochrome P450
MFLELIEK_03586 3e-136 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
MFLELIEK_03587 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_03588 3.3e-201 yvmA EGP Major facilitator Superfamily
MFLELIEK_03589 1.2e-50 yvlD S Membrane
MFLELIEK_03590 2.6e-26 pspB KT PspC domain
MFLELIEK_03591 7e-166 yvlB S Putative adhesin
MFLELIEK_03592 8e-49 yvlA
MFLELIEK_03593 5.7e-33 yvkN
MFLELIEK_03594 4.7e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFLELIEK_03595 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MFLELIEK_03596 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MFLELIEK_03597 1.2e-30 csbA S protein conserved in bacteria
MFLELIEK_03598 0.0 yvkC 2.7.9.2 GT Phosphotransferase
MFLELIEK_03599 1.3e-99 yvkB K Transcriptional regulator
MFLELIEK_03600 3.6e-225 yvkA EGP Major facilitator Superfamily
MFLELIEK_03601 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFLELIEK_03602 5.3e-56 swrA S Swarming motility protein
MFLELIEK_03603 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
MFLELIEK_03604 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
MFLELIEK_03605 1.6e-123 ftsE D cell division ATP-binding protein FtsE
MFLELIEK_03606 6.5e-54 cccB C COG2010 Cytochrome c, mono- and diheme variants
MFLELIEK_03607 9.3e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
MFLELIEK_03608 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MFLELIEK_03609 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MFLELIEK_03610 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MFLELIEK_03611 4.6e-51
MFLELIEK_03612 1.9e-08 fliT S bacterial-type flagellum organization
MFLELIEK_03613 6.5e-69 fliS N flagellar protein FliS
MFLELIEK_03614 1.5e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
MFLELIEK_03615 1.2e-55 flaG N flagellar protein FlaG
MFLELIEK_03616 1.6e-123 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
MFLELIEK_03617 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
MFLELIEK_03618 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
MFLELIEK_03619 2.6e-50 yviE
MFLELIEK_03620 1.1e-156 flgL N Belongs to the bacterial flagellin family
MFLELIEK_03621 1.2e-264 flgK N flagellar hook-associated protein
MFLELIEK_03622 2.4e-78 flgN NOU FlgN protein
MFLELIEK_03623 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
MFLELIEK_03624 7e-74 yvyF S flagellar protein
MFLELIEK_03625 2.7e-129 comFC S Phosphoribosyl transferase domain
MFLELIEK_03626 5.7e-46 comFB S Late competence development protein ComFB
MFLELIEK_03627 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MFLELIEK_03628 7.3e-155 degV S protein conserved in bacteria
MFLELIEK_03629 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
MFLELIEK_03630 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
MFLELIEK_03631 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
MFLELIEK_03632 6e-163 yvhJ K Transcriptional regulator
MFLELIEK_03633 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
MFLELIEK_03634 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
MFLELIEK_03635 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
MFLELIEK_03636 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
MFLELIEK_03637 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
MFLELIEK_03638 4.5e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFLELIEK_03639 7.6e-219 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
MFLELIEK_03640 5.3e-246 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
MFLELIEK_03641 7.8e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
MFLELIEK_03642 2.5e-267 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
MFLELIEK_03643 0.0 lytB 3.5.1.28 D Stage II sporulation protein
MFLELIEK_03644 6e-38
MFLELIEK_03645 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
MFLELIEK_03646 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MFLELIEK_03647 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFLELIEK_03648 6.5e-57
MFLELIEK_03649 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MFLELIEK_03650 7.5e-93 ggaA M Glycosyltransferase like family 2
MFLELIEK_03651 3e-39 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFLELIEK_03652 1.9e-54 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFLELIEK_03653 1.9e-36 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MFLELIEK_03654 9.2e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MFLELIEK_03655 4.1e-150 tagG GM Transport permease protein
MFLELIEK_03656 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFLELIEK_03657 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
MFLELIEK_03658 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
MFLELIEK_03659 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MFLELIEK_03660 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MFLELIEK_03661 3.5e-260
MFLELIEK_03662 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MFLELIEK_03663 5.7e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
MFLELIEK_03664 1.2e-261 gerBA EG Spore germination protein
MFLELIEK_03665 1.5e-192 gerBB E Spore germination protein
MFLELIEK_03666 3.2e-206 gerAC S Spore germination protein
MFLELIEK_03667 1.9e-248 ywtG EGP Major facilitator Superfamily
MFLELIEK_03668 8.4e-171 ywtF K Transcriptional regulator
MFLELIEK_03669 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
MFLELIEK_03670 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
MFLELIEK_03671 3.6e-21 ywtC
MFLELIEK_03672 1.1e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
MFLELIEK_03673 8.6e-70 pgsC S biosynthesis protein
MFLELIEK_03674 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
MFLELIEK_03675 9.3e-178 rbsR K transcriptional
MFLELIEK_03676 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MFLELIEK_03677 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MFLELIEK_03678 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
MFLELIEK_03679 2.1e-153 rbsC G Belongs to the binding-protein-dependent transport system permease family
MFLELIEK_03680 1.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
MFLELIEK_03681 8.7e-93 batE T Sh3 type 3 domain protein
MFLELIEK_03682 8e-48 ywsA S Protein of unknown function (DUF3892)
MFLELIEK_03683 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
MFLELIEK_03684 2.8e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
MFLELIEK_03685 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MFLELIEK_03686 1.1e-169 alsR K LysR substrate binding domain
MFLELIEK_03687 4.6e-219 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MFLELIEK_03688 7.5e-126 ywrJ
MFLELIEK_03689 2.9e-130 cotB
MFLELIEK_03690 3.5e-210 cotH M Spore Coat
MFLELIEK_03691 3.7e-12
MFLELIEK_03692 2e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MFLELIEK_03693 1.4e-53 S Domain of unknown function (DUF4181)
MFLELIEK_03694 1.4e-308 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
MFLELIEK_03695 8e-82 ywrC K Transcriptional regulator
MFLELIEK_03696 1.2e-103 ywrB P Chromate transporter
MFLELIEK_03697 9.9e-89 ywrA P COG2059 Chromate transport protein ChrA
MFLELIEK_03699 1.1e-100 ywqN S NAD(P)H-dependent
MFLELIEK_03700 1.4e-161 K Transcriptional regulator
MFLELIEK_03701 3.2e-119 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
MFLELIEK_03702 3.9e-25
MFLELIEK_03703 1.9e-82 ywqJ S Pre-toxin TG
MFLELIEK_03704 5.2e-17
MFLELIEK_03705 7.9e-43
MFLELIEK_03706 9.7e-213 ywqJ L nucleic acid phosphodiester bond hydrolysis
MFLELIEK_03707 8.6e-38 ywqI S Family of unknown function (DUF5344)
MFLELIEK_03708 9.7e-23 S Domain of unknown function (DUF5082)
MFLELIEK_03709 1.4e-152 ywqG S Domain of unknown function (DUF1963)
MFLELIEK_03710 3.7e-246 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
MFLELIEK_03711 5.1e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
MFLELIEK_03712 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
MFLELIEK_03713 2e-116 ywqC M biosynthesis protein
MFLELIEK_03714 1.2e-17
MFLELIEK_03715 1.4e-308 ywqB S SWIM zinc finger
MFLELIEK_03716 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
MFLELIEK_03717 1.3e-154 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
MFLELIEK_03718 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
MFLELIEK_03719 3.7e-57 ssbB L Single-stranded DNA-binding protein
MFLELIEK_03720 3.8e-66 ywpG
MFLELIEK_03721 1.1e-66 ywpF S YwpF-like protein
MFLELIEK_03722 1.2e-49 srtA 3.4.22.70 M Sortase family
MFLELIEK_03723 7e-153 ywpD T Histidine kinase
MFLELIEK_03724 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MFLELIEK_03725 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MFLELIEK_03726 8.8e-198 S aspartate phosphatase
MFLELIEK_03727 3.7e-140 flhP N flagellar basal body
MFLELIEK_03728 9.9e-125 flhO N flagellar basal body
MFLELIEK_03729 3.5e-180 mbl D Rod shape-determining protein
MFLELIEK_03730 3e-44 spoIIID K Stage III sporulation protein D
MFLELIEK_03731 2.1e-70 ywoH K COG1846 Transcriptional regulators
MFLELIEK_03732 3.9e-210 ywoG EGP Major facilitator Superfamily
MFLELIEK_03733 9.8e-229 ywoF P Right handed beta helix region
MFLELIEK_03734 3.4e-280 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
MFLELIEK_03735 2.4e-240 ywoD EGP Major facilitator superfamily
MFLELIEK_03736 3.4e-103 phzA Q Isochorismatase family
MFLELIEK_03737 2.6e-77
MFLELIEK_03738 4.3e-225 amt P Ammonium transporter
MFLELIEK_03739 1.6e-58 nrgB K Belongs to the P(II) protein family
MFLELIEK_03740 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
MFLELIEK_03741 2.5e-71 ywnJ S VanZ like family
MFLELIEK_03742 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
MFLELIEK_03743 1.2e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
MFLELIEK_03744 1.3e-08 ywnC S Family of unknown function (DUF5362)
MFLELIEK_03745 1.5e-189 spsF 2.5.1.56, 2.7.7.92 M NeuB family
MFLELIEK_03746 2.2e-70 ywnF S Family of unknown function (DUF5392)
MFLELIEK_03747 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFLELIEK_03748 2.6e-143 mta K transcriptional
MFLELIEK_03749 2.6e-59 ywnC S Family of unknown function (DUF5362)
MFLELIEK_03750 9.9e-112 ywnB S NAD(P)H-binding
MFLELIEK_03751 1.7e-64 ywnA K Transcriptional regulator
MFLELIEK_03752 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
MFLELIEK_03753 1.7e-63 ureB 3.5.1.5 E Belongs to the urease beta subunit family
MFLELIEK_03754 1.4e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
MFLELIEK_03755 3.8e-11 csbD K CsbD-like
MFLELIEK_03756 3e-84 ywmF S Peptidase M50
MFLELIEK_03757 7.9e-104 S response regulator aspartate phosphatase
MFLELIEK_03758 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MFLELIEK_03759 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MFLELIEK_03761 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
MFLELIEK_03762 3e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
MFLELIEK_03763 9.2e-176 spoIID D Stage II sporulation protein D
MFLELIEK_03764 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFLELIEK_03765 8.2e-134 ywmB S TATA-box binding
MFLELIEK_03766 1.3e-32 ywzB S membrane
MFLELIEK_03767 4.1e-86 ywmA
MFLELIEK_03768 9.4e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MFLELIEK_03769 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MFLELIEK_03770 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MFLELIEK_03771 1.7e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MFLELIEK_03772 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFLELIEK_03773 1.6e-40 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MFLELIEK_03774 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MFLELIEK_03775 1.3e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MFLELIEK_03776 2.5e-62 atpI S ATP synthase
MFLELIEK_03777 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MFLELIEK_03778 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MFLELIEK_03779 7.2e-95 ywlG S Belongs to the UPF0340 family
MFLELIEK_03780 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
MFLELIEK_03781 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MFLELIEK_03782 1.7e-91 mntP P Probably functions as a manganese efflux pump
MFLELIEK_03783 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MFLELIEK_03784 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
MFLELIEK_03785 6.1e-112 spoIIR S stage II sporulation protein R
MFLELIEK_03786 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
MFLELIEK_03788 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MFLELIEK_03789 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MFLELIEK_03790 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_03791 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
MFLELIEK_03792 8.6e-160 ywkB S Membrane transport protein
MFLELIEK_03793 0.0 sfcA 1.1.1.38 C malic enzyme
MFLELIEK_03794 1.6e-103 tdk 2.7.1.21 F thymidine kinase
MFLELIEK_03795 1.1e-32 rpmE J Binds the 23S rRNA
MFLELIEK_03796 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MFLELIEK_03797 9.5e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
MFLELIEK_03798 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MFLELIEK_03799 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MFLELIEK_03800 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
MFLELIEK_03801 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
MFLELIEK_03802 1.8e-90 ywjG S Domain of unknown function (DUF2529)
MFLELIEK_03803 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MFLELIEK_03804 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MFLELIEK_03805 2.8e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
MFLELIEK_03806 0.0 fadF C COG0247 Fe-S oxidoreductase
MFLELIEK_03807 1.7e-221 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
MFLELIEK_03808 5.6e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
MFLELIEK_03809 1.1e-95 ywjB H RibD C-terminal domain
MFLELIEK_03810 9.7e-272 ywjA V ABC transporter
MFLELIEK_03811 8.3e-30 ywjA V ABC transporter
MFLELIEK_03812 3.5e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MFLELIEK_03813 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
MFLELIEK_03814 3.6e-94 narJ 1.7.5.1 C nitrate reductase
MFLELIEK_03815 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
MFLELIEK_03816 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFLELIEK_03817 7e-86 arfM T cyclic nucleotide binding
MFLELIEK_03818 1.7e-139 ywiC S YwiC-like protein
MFLELIEK_03819 7.7e-129 fnr K helix_turn_helix, cAMP Regulatory protein
MFLELIEK_03820 2.3e-213 narK P COG2223 Nitrate nitrite transporter
MFLELIEK_03821 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MFLELIEK_03822 4.7e-73 ywiB S protein conserved in bacteria
MFLELIEK_03823 1e-07 S Bacteriocin subtilosin A
MFLELIEK_03824 4.9e-270 C Fe-S oxidoreductases
MFLELIEK_03826 3.3e-132 cbiO V ABC transporter
MFLELIEK_03827 3.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
MFLELIEK_03828 4.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
MFLELIEK_03829 1.6e-249 L Peptidase, M16
MFLELIEK_03831 4.7e-244 ywhL CO amine dehydrogenase activity
MFLELIEK_03832 1.5e-186 ywhK CO amine dehydrogenase activity
MFLELIEK_03833 4.4e-78 S aspartate phosphatase
MFLELIEK_03835 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
MFLELIEK_03836 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
MFLELIEK_03837 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
MFLELIEK_03838 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MFLELIEK_03839 3.6e-49
MFLELIEK_03840 5.2e-95 ywhD S YwhD family
MFLELIEK_03841 5.1e-119 ywhC S Peptidase family M50
MFLELIEK_03842 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
MFLELIEK_03843 9.5e-71 ywhA K Transcriptional regulator
MFLELIEK_03844 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MFLELIEK_03846 9.8e-237 mmr U Major Facilitator Superfamily
MFLELIEK_03847 6.2e-79 yffB K Transcriptional regulator
MFLELIEK_03848 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
MFLELIEK_03849 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
MFLELIEK_03850 3.1e-36 ywzC S Belongs to the UPF0741 family
MFLELIEK_03851 5.1e-110 rsfA_1
MFLELIEK_03852 1.6e-155 ywfM EG EamA-like transporter family
MFLELIEK_03853 8.7e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
MFLELIEK_03854 1.1e-156 cysL K Transcriptional regulator
MFLELIEK_03855 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
MFLELIEK_03856 1.1e-146 ywfI C May function as heme-dependent peroxidase
MFLELIEK_03857 1.1e-136 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_03858 5e-234 ywfG 2.6.1.83 E Aminotransferase class I and II
MFLELIEK_03859 1.9e-209 bacE EGP Major facilitator Superfamily
MFLELIEK_03860 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
MFLELIEK_03861 2.5e-138 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_03862 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
MFLELIEK_03863 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
MFLELIEK_03864 6e-206 ywfA EGP Major facilitator Superfamily
MFLELIEK_03865 4.8e-249 lysP E amino acid
MFLELIEK_03866 4.3e-35 rocB E arginine degradation protein
MFLELIEK_03867 1.1e-48 rocB E arginine degradation protein
MFLELIEK_03868 5.1e-220 rocB E arginine degradation protein
MFLELIEK_03869 1.7e-295 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
MFLELIEK_03870 2.8e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
MFLELIEK_03871 4.4e-77
MFLELIEK_03872 3.5e-87 spsL 5.1.3.13 M Spore Coat
MFLELIEK_03873 1.5e-160 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MFLELIEK_03874 5.7e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MFLELIEK_03875 7.1e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MFLELIEK_03876 1e-187 spsG M Spore Coat
MFLELIEK_03877 2.4e-130 spsF M Spore Coat
MFLELIEK_03878 3.5e-213 spsE 2.5.1.56 M acid synthase
MFLELIEK_03879 1.7e-162 spsD 2.3.1.210 K Spore Coat
MFLELIEK_03880 2.1e-224 spsC E Belongs to the DegT DnrJ EryC1 family
MFLELIEK_03881 9.8e-266 spsB M Capsule polysaccharide biosynthesis protein
MFLELIEK_03882 7.7e-143 spsA M Spore Coat
MFLELIEK_03883 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
MFLELIEK_03884 4.3e-59 ywdK S small membrane protein
MFLELIEK_03885 1.1e-237 ywdJ F Xanthine uracil
MFLELIEK_03886 1.7e-48 ywdI S Family of unknown function (DUF5327)
MFLELIEK_03887 2.9e-262 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MFLELIEK_03888 1.1e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MFLELIEK_03889 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
MFLELIEK_03891 1.3e-111 ywdD
MFLELIEK_03892 1.3e-57 pex K Transcriptional regulator PadR-like family
MFLELIEK_03893 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MFLELIEK_03894 2e-28 ywdA
MFLELIEK_03895 3e-289 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
MFLELIEK_03896 4.7e-252 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_03897 2.6e-138 focA P Formate/nitrite transporter
MFLELIEK_03898 7e-150 sacT K transcriptional antiterminator
MFLELIEK_03900 0.0 vpr O Belongs to the peptidase S8 family
MFLELIEK_03901 3.6e-185 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_03902 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
MFLELIEK_03903 8.6e-202 rodA D Belongs to the SEDS family
MFLELIEK_03904 5.2e-204 S Acetyltransferase
MFLELIEK_03905 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
MFLELIEK_03906 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MFLELIEK_03907 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
MFLELIEK_03908 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MFLELIEK_03909 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
MFLELIEK_03910 1e-35 ywzA S membrane
MFLELIEK_03911 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MFLELIEK_03912 2.9e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MFLELIEK_03913 8.1e-59 gtcA S GtrA-like protein
MFLELIEK_03914 3.2e-121 ywcC K transcriptional regulator
MFLELIEK_03916 9.8e-49 ywcB S Protein of unknown function, DUF485
MFLELIEK_03917 6.9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MFLELIEK_03918 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
MFLELIEK_03919 3.2e-223 ywbN P Dyp-type peroxidase family protein
MFLELIEK_03920 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
MFLELIEK_03921 9e-254 P COG0672 High-affinity Fe2 Pb2 permease
MFLELIEK_03922 4.5e-115 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MFLELIEK_03923 2e-141 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MFLELIEK_03924 2.1e-152 ywbI K Transcriptional regulator
MFLELIEK_03925 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
MFLELIEK_03926 6.8e-111 ywbG M effector of murein hydrolase
MFLELIEK_03927 1.5e-206 ywbF EGP Major facilitator Superfamily
MFLELIEK_03928 1.4e-27 ywbE S Uncharacterized conserved protein (DUF2196)
MFLELIEK_03929 1.3e-221 ywbD 2.1.1.191 J Methyltransferase
MFLELIEK_03930 4.4e-67 ywbC 4.4.1.5 E glyoxalase
MFLELIEK_03931 2e-123 ywbB S Protein of unknown function (DUF2711)
MFLELIEK_03932 1.6e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLELIEK_03933 4.3e-275 epr 3.4.21.62 O Belongs to the peptidase S8 family
MFLELIEK_03934 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_03935 3.8e-151 sacY K transcriptional antiterminator
MFLELIEK_03936 4.5e-168 gspA M General stress
MFLELIEK_03937 1.5e-124 ywaF S Integral membrane protein
MFLELIEK_03938 1.2e-86 ywaE K Transcriptional regulator
MFLELIEK_03939 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MFLELIEK_03940 3.7e-249 ywaD 3.4.11.10, 3.4.11.6 S PA domain
MFLELIEK_03941 4e-92 K Helix-turn-helix XRE-family like proteins
MFLELIEK_03942 3.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
MFLELIEK_03943 8.8e-130 ynfM EGP Major facilitator Superfamily
MFLELIEK_03944 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
MFLELIEK_03945 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
MFLELIEK_03946 5e-14 S D-Ala-teichoic acid biosynthesis protein
MFLELIEK_03947 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_03948 3.6e-232 dltB M membrane protein involved in D-alanine export
MFLELIEK_03949 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MFLELIEK_03950 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MFLELIEK_03951 8.1e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_03952 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MFLELIEK_03953 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
MFLELIEK_03954 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
MFLELIEK_03955 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MFLELIEK_03956 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
MFLELIEK_03957 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
MFLELIEK_03958 1.1e-19 yxzF
MFLELIEK_03959 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MFLELIEK_03960 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
MFLELIEK_03961 5.3e-215 yxlH EGP Major facilitator Superfamily
MFLELIEK_03962 2.6e-138 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MFLELIEK_03963 8.2e-165 yxlF V ABC transporter, ATP-binding protein
MFLELIEK_03964 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
MFLELIEK_03965 1.4e-30
MFLELIEK_03966 1.6e-46 yxlC S Family of unknown function (DUF5345)
MFLELIEK_03967 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
MFLELIEK_03968 6.6e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
MFLELIEK_03969 1.4e-158 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MFLELIEK_03970 0.0 cydD V ATP-binding protein
MFLELIEK_03971 4e-309 cydD V ATP-binding
MFLELIEK_03972 8.4e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
MFLELIEK_03973 6.9e-267 cydA 1.10.3.14 C oxidase, subunit
MFLELIEK_03974 2.1e-228 cimH C COG3493 Na citrate symporter
MFLELIEK_03975 2.3e-309 3.4.24.84 O Peptidase family M48
MFLELIEK_03977 9.9e-152 yxkH G Polysaccharide deacetylase
MFLELIEK_03978 5.9e-205 msmK P Belongs to the ABC transporter superfamily
MFLELIEK_03979 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
MFLELIEK_03980 2.5e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFLELIEK_03981 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MFLELIEK_03982 2.8e-74 yxkC S Domain of unknown function (DUF4352)
MFLELIEK_03983 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MFLELIEK_03984 7.7e-77 S Protein of unknown function (DUF1453)
MFLELIEK_03985 1.6e-190 yxjM T Signal transduction histidine kinase
MFLELIEK_03986 9.8e-115 K helix_turn_helix, Lux Regulon
MFLELIEK_03987 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MFLELIEK_03989 1.4e-86 yxjI S LURP-one-related
MFLELIEK_03990 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
MFLELIEK_03991 1e-220 yxjG 2.1.1.14 E Methionine synthase
MFLELIEK_03992 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
MFLELIEK_03993 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
MFLELIEK_03994 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MFLELIEK_03995 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
MFLELIEK_03996 2.1e-157 rlmA 2.1.1.187 Q Methyltransferase domain
MFLELIEK_03997 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFLELIEK_03998 1.5e-102 T Domain of unknown function (DUF4163)
MFLELIEK_03999 3e-47 yxiS
MFLELIEK_04000 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
MFLELIEK_04001 6.6e-224 citH C Citrate transporter
MFLELIEK_04002 3.6e-142 exoK GH16 M licheninase activity
MFLELIEK_04003 8.3e-151 licT K transcriptional antiterminator
MFLELIEK_04004 6.2e-112
MFLELIEK_04005 6.8e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
MFLELIEK_04006 7.6e-247 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
MFLELIEK_04007 4.3e-214 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
MFLELIEK_04008 7.8e-55 padR K Transcriptional regulator PadR-like family
MFLELIEK_04009 6.5e-61 S Protein of unknown function (DUF2812)
MFLELIEK_04012 4.5e-43 yxiJ S YxiJ-like protein
MFLELIEK_04015 1.2e-34
MFLELIEK_04016 1.1e-83 yxiI S Protein of unknown function (DUF2716)
MFLELIEK_04017 1.5e-136
MFLELIEK_04018 8.3e-13 yxiG
MFLELIEK_04019 5.3e-16 yxiG
MFLELIEK_04020 1.9e-38 S Protein of unknown function (DUF2750)
MFLELIEK_04021 3.4e-52 yxxG
MFLELIEK_04022 1.2e-65 yxiG
MFLELIEK_04023 7.1e-44
MFLELIEK_04024 3.8e-76
MFLELIEK_04025 4.7e-94 S Protein of unknown function (DUF4240)
MFLELIEK_04026 4.5e-141
MFLELIEK_04028 7e-55
MFLELIEK_04029 7.2e-81 wapA M COG3209 Rhs family protein
MFLELIEK_04030 3.1e-14 yxiJ S YxiJ-like protein
MFLELIEK_04031 0.0 wapA M COG3209 Rhs family protein
MFLELIEK_04032 1.3e-165 yxxF EG EamA-like transporter family
MFLELIEK_04033 9.7e-127 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MFLELIEK_04034 1.3e-120 1.14.11.45 E 2OG-Fe dioxygenase
MFLELIEK_04035 1.8e-72 yxiE T Belongs to the universal stress protein A family
MFLELIEK_04036 2.4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFLELIEK_04037 3.8e-310 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MFLELIEK_04038 3.3e-32
MFLELIEK_04039 2e-99 S nuclease activity
MFLELIEK_04040 4.1e-21 S Immunity protein 8
MFLELIEK_04041 8.4e-216 S nuclease activity
MFLELIEK_04042 4e-38 yxiC S Family of unknown function (DUF5344)
MFLELIEK_04043 2.3e-20 S Domain of unknown function (DUF5082)
MFLELIEK_04044 2.8e-276 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
MFLELIEK_04045 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
MFLELIEK_04046 4.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
MFLELIEK_04047 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MFLELIEK_04048 1.7e-235 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
MFLELIEK_04049 1.5e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
MFLELIEK_04050 3.4e-250 lysP E amino acid
MFLELIEK_04051 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
MFLELIEK_04052 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MFLELIEK_04053 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MFLELIEK_04054 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
MFLELIEK_04055 2e-152 yxxB S Domain of Unknown Function (DUF1206)
MFLELIEK_04056 1.3e-196 eutH E Ethanolamine utilisation protein, EutH
MFLELIEK_04057 4e-248 yxeQ S MmgE/PrpD family
MFLELIEK_04058 2.3e-212 yxeP 3.5.1.47 E hydrolase activity
MFLELIEK_04059 4.7e-129 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
MFLELIEK_04060 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
MFLELIEK_04061 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
MFLELIEK_04062 1.6e-93 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MFLELIEK_04063 2.8e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MFLELIEK_04064 2.2e-187 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MFLELIEK_04065 2.6e-149 yidA S hydrolases of the HAD superfamily
MFLELIEK_04068 1.3e-20 yxeE
MFLELIEK_04070 1.4e-68
MFLELIEK_04071 1.5e-175 fhuD P ABC transporter
MFLELIEK_04072 1.5e-58 yxeA S Protein of unknown function (DUF1093)
MFLELIEK_04073 0.0 yxdM V ABC transporter (permease)
MFLELIEK_04074 9.4e-141 yxdL V ABC transporter, ATP-binding protein
MFLELIEK_04075 5.8e-180 T PhoQ Sensor
MFLELIEK_04076 9.3e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_04077 3.3e-158 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
MFLELIEK_04078 1.6e-138 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
MFLELIEK_04079 2.5e-166 iolH G Xylose isomerase-like TIM barrel
MFLELIEK_04080 6.1e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
MFLELIEK_04081 2.5e-234 iolF EGP Major facilitator Superfamily
MFLELIEK_04082 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
MFLELIEK_04083 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
MFLELIEK_04084 1.6e-177 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
MFLELIEK_04085 1.7e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
MFLELIEK_04086 3e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
MFLELIEK_04087 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
MFLELIEK_04088 4.1e-175 iolS C Aldo keto reductase
MFLELIEK_04090 1.9e-47 yxcD S Protein of unknown function (DUF2653)
MFLELIEK_04091 1.1e-245 csbC EGP Major facilitator Superfamily
MFLELIEK_04092 0.0 htpG O Molecular chaperone. Has ATPase activity
MFLELIEK_04094 1.3e-148 IQ Enoyl-(Acyl carrier protein) reductase
MFLELIEK_04095 8.3e-210 yxbF K Bacterial regulatory proteins, tetR family
MFLELIEK_04096 3.2e-245 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
MFLELIEK_04097 3.7e-26 yxaI S membrane protein domain
MFLELIEK_04098 2.5e-63 S Family of unknown function (DUF5391)
MFLELIEK_04099 1.1e-75 yxaI S membrane protein domain
MFLELIEK_04100 1.4e-228 P Protein of unknown function (DUF418)
MFLELIEK_04101 1.3e-198 yxaG 1.13.11.24 S AraC-like ligand binding domain
MFLELIEK_04102 1.2e-100 yxaF K Transcriptional regulator
MFLELIEK_04103 1.7e-25 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_04104 6.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MFLELIEK_04105 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
MFLELIEK_04106 5.2e-50 S LrgA family
MFLELIEK_04107 1.3e-117 yxaC M effector of murein hydrolase
MFLELIEK_04108 3.5e-91 yxaB GM Polysaccharide pyruvyl transferase
MFLELIEK_04109 4.6e-38 yxaB GM Polysaccharide pyruvyl transferase
MFLELIEK_04110 1.9e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MFLELIEK_04111 2.8e-126 gntR K transcriptional
MFLELIEK_04112 2.8e-301 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MFLELIEK_04113 1e-230 gntP EG COG2610 H gluconate symporter and related permeases
MFLELIEK_04114 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MFLELIEK_04115 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
MFLELIEK_04116 2.5e-286 ahpF O Alkyl hydroperoxide reductase
MFLELIEK_04117 7.8e-290 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MFLELIEK_04118 6.9e-19 bglF G phosphotransferase system
MFLELIEK_04119 1.1e-124 yydK K Transcriptional regulator
MFLELIEK_04120 1.6e-118 S ABC-2 family transporter protein
MFLELIEK_04121 1.6e-109 prrC P ABC transporter
MFLELIEK_04122 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
MFLELIEK_04123 1.3e-202 S SIR2-like domain
MFLELIEK_04124 1.1e-180 L DNA synthesis involved in DNA repair
MFLELIEK_04125 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MFLELIEK_04126 1.1e-09 S YyzF-like protein
MFLELIEK_04127 1.3e-67
MFLELIEK_04128 3.9e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
MFLELIEK_04130 9.7e-31 yycQ S Protein of unknown function (DUF2651)
MFLELIEK_04131 3.5e-200 yycP
MFLELIEK_04132 8.4e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
MFLELIEK_04133 1.4e-83 yycN 2.3.1.128 K Acetyltransferase
MFLELIEK_04134 1.1e-187 S aspartate phosphatase
MFLELIEK_04136 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
MFLELIEK_04137 1.3e-260 rocE E amino acid
MFLELIEK_04138 2.5e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
MFLELIEK_04139 7.4e-16
MFLELIEK_04140 2.8e-94
MFLELIEK_04141 2.3e-24 S Sporulation delaying protein SdpA
MFLELIEK_04142 1.5e-59 S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
MFLELIEK_04143 1.5e-40 sdpR K transcriptional
MFLELIEK_04144 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
MFLELIEK_04145 8.7e-218 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MFLELIEK_04146 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
MFLELIEK_04147 7.3e-155 yycI S protein conserved in bacteria
MFLELIEK_04148 5.8e-258 yycH S protein conserved in bacteria
MFLELIEK_04149 0.0 vicK 2.7.13.3 T Histidine kinase
MFLELIEK_04150 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
MFLELIEK_04155 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MFLELIEK_04156 5.8e-76 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_04157 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MFLELIEK_04158 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
MFLELIEK_04160 1.9e-15 yycC K YycC-like protein
MFLELIEK_04161 8.4e-221 yeaN P COG2807 Cyanate permease
MFLELIEK_04162 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MFLELIEK_04163 2.2e-73 rplI J binds to the 23S rRNA
MFLELIEK_04164 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MFLELIEK_04165 8.3e-160 yybS S membrane
MFLELIEK_04167 3.9e-84 cotF M Spore coat protein
MFLELIEK_04168 1.7e-66 ydeP3 K Transcriptional regulator
MFLELIEK_04169 1.9e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
MFLELIEK_04170 1.5e-58
MFLELIEK_04172 6.7e-240 yybO G COG0477 Permeases of the major facilitator superfamily
MFLELIEK_04173 4.3e-111 K TipAS antibiotic-recognition domain
MFLELIEK_04174 4.8e-124
MFLELIEK_04175 8.6e-66 yybH S SnoaL-like domain
MFLELIEK_04176 1.4e-118 yybG S Pentapeptide repeat-containing protein
MFLELIEK_04177 2.8e-216 ynfM EGP Major facilitator Superfamily
MFLELIEK_04178 4e-164 yybE K Transcriptional regulator
MFLELIEK_04179 2e-79 yjcF S Acetyltransferase (GNAT) domain
MFLELIEK_04180 3e-76 yybC
MFLELIEK_04181 3.3e-126 S Metallo-beta-lactamase superfamily
MFLELIEK_04182 5.6e-77 yybA 2.3.1.57 K transcriptional
MFLELIEK_04183 2e-71 yjcF S Acetyltransferase (GNAT) domain
MFLELIEK_04184 5.5e-96 yyaS S Membrane
MFLELIEK_04185 1.6e-91 yyaR K Acetyltransferase (GNAT) domain
MFLELIEK_04186 4.6e-66 yyaQ S YjbR
MFLELIEK_04187 8.5e-107 yyaP 1.5.1.3 H RibD C-terminal domain
MFLELIEK_04188 2.5e-19 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFLELIEK_04189 1.6e-244 tetL EGP Major facilitator Superfamily
MFLELIEK_04190 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
MFLELIEK_04191 1.5e-181 arsB 1.20.4.1 P Arsenic resistance protein
MFLELIEK_04192 1.4e-64 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_04193 2.1e-54 arsR K ArsR family transcriptional regulator
MFLELIEK_04194 3.8e-53 L Recombinase
MFLELIEK_04195 1.1e-08
MFLELIEK_04196 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
MFLELIEK_04197 5.9e-83 yddI
MFLELIEK_04198 9.4e-186 yddH CBM50 M Lysozyme-like
MFLELIEK_04199 0.0 yddG S maturation of SSU-rRNA
MFLELIEK_04200 4.4e-55 S Domain of unknown function (DUF1874)
MFLELIEK_04201 0.0 yddE S AAA-like domain
MFLELIEK_04202 8.8e-90 yddD S TcpE family
MFLELIEK_04203 3.7e-38 yddC
MFLELIEK_04204 4.1e-163 yddB S Conjugative transposon protein TcpC
MFLELIEK_04207 1.9e-200 nicK L Replication initiation factor
MFLELIEK_04208 3.9e-206 ydcQ D Ftsk spoiiie family protein
MFLELIEK_04209 6e-64 S Bacterial protein of unknown function (DUF961)
MFLELIEK_04211 4.7e-36
MFLELIEK_04212 2.1e-14
MFLELIEK_04213 1.4e-41 yvaO K Transcriptional
MFLELIEK_04214 5.1e-45 immA E IrrE N-terminal-like domain
MFLELIEK_04215 8.2e-67 S response regulator aspartate phosphatase
MFLELIEK_04218 5.7e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFLELIEK_04219 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
MFLELIEK_04220 3.6e-168 yyaK S CAAX protease self-immunity
MFLELIEK_04221 3.2e-245 EGP Major facilitator superfamily
MFLELIEK_04222 6.8e-93 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
MFLELIEK_04223 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MFLELIEK_04224 1.8e-178 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
MFLELIEK_04225 4e-144 xth 3.1.11.2 L exodeoxyribonuclease III
MFLELIEK_04226 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MFLELIEK_04227 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MFLELIEK_04228 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
MFLELIEK_04229 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MFLELIEK_04230 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MFLELIEK_04231 2.3e-33 yyzM S protein conserved in bacteria
MFLELIEK_04232 4e-176 yyaD S Membrane
MFLELIEK_04233 2.1e-111 yyaC S Sporulation protein YyaC
MFLELIEK_04234 3.9e-148 spo0J K Belongs to the ParB family
MFLELIEK_04235 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
MFLELIEK_04236 1.1e-72 S Bacterial PH domain
MFLELIEK_04237 5.5e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
MFLELIEK_04238 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
MFLELIEK_04239 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MFLELIEK_04240 8.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MFLELIEK_04241 6.5e-108 jag S single-stranded nucleic acid binding R3H
MFLELIEK_04242 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MFLELIEK_04243 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MFLELIEK_04244 1.5e-175 S Phage tail protein
MFLELIEK_04245 2.4e-147 S Phage minor structural protein
MFLELIEK_04246 4e-23
MFLELIEK_04247 6e-76 S N-acetylmuramoyl-L-alanine amidase activity
MFLELIEK_04248 3e-12
MFLELIEK_04251 4.3e-09 S SPP1 phage holin
MFLELIEK_04252 1.4e-107 3.1.3.5, 3.1.3.6, 3.1.4.16, 3.6.1.45 CBM50 M Glycosyl hydrolases family 25
MFLELIEK_04253 1.2e-97 S Phage integrase family
MFLELIEK_04254 1.3e-171 A Pre-toxin TG
MFLELIEK_04255 3.1e-66 S Immunity protein 70
MFLELIEK_04256 2.2e-27 S Domain of unknown function (DUF4935)
MFLELIEK_04258 5.4e-13 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MFLELIEK_04264 3.4e-57 traC L Domain of unknown function (DUF1738)
MFLELIEK_04265 7e-148 S DNA gyrase/topoisomerase IV, subunit A
MFLELIEK_04266 2.6e-184 S DNA gyrase B
MFLELIEK_04267 4e-15 repA S Replication initiator protein A (RepA) N-terminus
MFLELIEK_04269 9.1e-11 tdk 2.7.1.21 F Psort location Cytoplasmic, score 8.87
MFLELIEK_04274 3.3e-18 S Endodeoxyribonuclease RusA
MFLELIEK_04275 3.7e-22 2.7.4.8 F Guanylate kinase homologues.
MFLELIEK_04279 0.0 S Bacterial DNA polymerase III alpha subunit
MFLELIEK_04281 4.4e-10 thyX 2.1.1.148 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant
MFLELIEK_04283 1.8e-46 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MFLELIEK_04286 1.3e-06 yfbR S HD containing hydrolase-like enzyme
MFLELIEK_04288 2.3e-17 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MFLELIEK_04289 2.4e-15 K Transcriptional regulator
MFLELIEK_04290 3.6e-87 S exonuclease activity
MFLELIEK_04292 8.3e-36 S DNA primase activity
MFLELIEK_04293 1.1e-39 S DNA primase activity
MFLELIEK_04294 1.6e-110 S DNA helicase activity
MFLELIEK_04295 1.3e-15
MFLELIEK_04296 1.6e-24
MFLELIEK_04299 1e-39
MFLELIEK_04301 3.4e-10 fld C flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group
MFLELIEK_04302 1.2e-103 S Ribonucleotide reductase, small chain
MFLELIEK_04303 7.3e-277 S ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
MFLELIEK_04304 1.9e-64 S AAA domain
MFLELIEK_04307 8.2e-48 F Nucleoside 2-deoxyribosyltransferase
MFLELIEK_04308 6.6e-35
MFLELIEK_04310 5.9e-07
MFLELIEK_04311 1.5e-31 yxcD S Protein of unknown function (DUF2653)
MFLELIEK_04313 8.1e-20
MFLELIEK_04314 2e-41 XK27_03185 S Phosphoribosyl-ATP pyrophosphohydrolase
MFLELIEK_04317 2.9e-52
MFLELIEK_04318 3.6e-73 L integrase family
MFLELIEK_04321 1.6e-22 yocH 3.5.1.28 M 3D domain
MFLELIEK_04322 1.2e-68 lig 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP dependent DNA ligase domain
MFLELIEK_04324 4.8e-82
MFLELIEK_04326 5e-178 S response regulator aspartate phosphatase
MFLELIEK_04329 8.1e-29 S Phage terminase, small subunit
MFLELIEK_04332 6.9e-45 S endonuclease activity
MFLELIEK_04333 4.2e-134 S Phage Terminase
MFLELIEK_04334 5.5e-107 S Phage portal protein
MFLELIEK_04335 7.6e-23 S Caudovirus prohead serine protease
MFLELIEK_04336 6.6e-20 S Caudovirus prohead serine protease
MFLELIEK_04337 3.1e-87 S Phage capsid family
MFLELIEK_04339 8.5e-22 S DNA packaging
MFLELIEK_04340 1.8e-11 S Phage head-tail joining protein
MFLELIEK_04341 7.4e-14 S Bacteriophage HK97-gp10, putative tail-component
MFLELIEK_04342 1.9e-07
MFLELIEK_04343 1.6e-40 S Phage tail tube protein
MFLELIEK_04345 3.1e-152 D Phage tail tape measure protein

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)