ORF_ID e_value Gene_name EC_number CAZy COGs Description
GPNPHLCG_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GPNPHLCG_00002 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
GPNPHLCG_00003 2.4e-33 yaaA S S4 domain
GPNPHLCG_00004 2.7e-205 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GPNPHLCG_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
GPNPHLCG_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPNPHLCG_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GPNPHLCG_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00011 8.7e-181 yaaC S YaaC-like Protein
GPNPHLCG_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
GPNPHLCG_00013 6.8e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
GPNPHLCG_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GPNPHLCG_00015 2.3e-107 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GPNPHLCG_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GPNPHLCG_00017 1.3e-09
GPNPHLCG_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
GPNPHLCG_00019 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
GPNPHLCG_00020 1.2e-212 yaaH M Glycoside Hydrolase Family
GPNPHLCG_00021 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
GPNPHLCG_00022 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
GPNPHLCG_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPNPHLCG_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GPNPHLCG_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GPNPHLCG_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
GPNPHLCG_00027 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA
GPNPHLCG_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00031 1.7e-30 csfB S Inhibitor of sigma-G Gin
GPNPHLCG_00032 2e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
GPNPHLCG_00033 2.2e-202 yaaN P Belongs to the TelA family
GPNPHLCG_00034 1.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
GPNPHLCG_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GPNPHLCG_00036 2.2e-54 yaaQ S protein conserved in bacteria
GPNPHLCG_00037 4.5e-71 yaaR S protein conserved in bacteria
GPNPHLCG_00038 1.1e-181 holB 2.7.7.7 L DNA polymerase III
GPNPHLCG_00039 6.1e-146 yaaT S stage 0 sporulation protein
GPNPHLCG_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
GPNPHLCG_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
GPNPHLCG_00042 1.5e-49 yazA L endonuclease containing a URI domain
GPNPHLCG_00043 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GPNPHLCG_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
GPNPHLCG_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GPNPHLCG_00046 1e-142 tatD L hydrolase, TatD
GPNPHLCG_00047 2e-167 rpfB GH23 T protein conserved in bacteria
GPNPHLCG_00048 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
GPNPHLCG_00049 1.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
GPNPHLCG_00050 1.6e-136 yabG S peptidase
GPNPHLCG_00051 7.8e-39 veg S protein conserved in bacteria
GPNPHLCG_00052 2e-26 sspF S DNA topological change
GPNPHLCG_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GPNPHLCG_00054 5.9e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
GPNPHLCG_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
GPNPHLCG_00056 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
GPNPHLCG_00057 1.2e-228 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GPNPHLCG_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GPNPHLCG_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GPNPHLCG_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
GPNPHLCG_00061 2.4e-39 yabK S Peptide ABC transporter permease
GPNPHLCG_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GPNPHLCG_00063 1.5e-92 spoVT K stage V sporulation protein
GPNPHLCG_00064 7.1e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_00065 3.3e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
GPNPHLCG_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
GPNPHLCG_00067 1.5e-49 yabP S Sporulation protein YabP
GPNPHLCG_00068 9.5e-107 yabQ S spore cortex biosynthesis protein
GPNPHLCG_00069 1.1e-44 divIC D Septum formation initiator
GPNPHLCG_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
GPNPHLCG_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
GPNPHLCG_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
GPNPHLCG_00075 1.5e-183 KLT serine threonine protein kinase
GPNPHLCG_00076 8.5e-273 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
GPNPHLCG_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
GPNPHLCG_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GPNPHLCG_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GPNPHLCG_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
GPNPHLCG_00081 6.8e-159 yacD 5.2.1.8 O peptidyl-prolyl isomerase
GPNPHLCG_00082 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPNPHLCG_00083 6.1e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPNPHLCG_00084 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
GPNPHLCG_00085 2.5e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
GPNPHLCG_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GPNPHLCG_00087 5.9e-61 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GPNPHLCG_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GPNPHLCG_00089 4.1e-30 yazB K transcriptional
GPNPHLCG_00090 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPNPHLCG_00091 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
GPNPHLCG_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00097 2e-08
GPNPHLCG_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00103 2.9e-76 ctsR K Belongs to the CtsR family
GPNPHLCG_00104 1.6e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
GPNPHLCG_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
GPNPHLCG_00106 0.0 clpC O Belongs to the ClpA ClpB family
GPNPHLCG_00107 4e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GPNPHLCG_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GPNPHLCG_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
GPNPHLCG_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
GPNPHLCG_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
GPNPHLCG_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GPNPHLCG_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
GPNPHLCG_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPNPHLCG_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
GPNPHLCG_00116 5.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPNPHLCG_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
GPNPHLCG_00118 4.4e-115 sigH K Belongs to the sigma-70 factor family
GPNPHLCG_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
GPNPHLCG_00120 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
GPNPHLCG_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GPNPHLCG_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
GPNPHLCG_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GPNPHLCG_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
GPNPHLCG_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
GPNPHLCG_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNPHLCG_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNPHLCG_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
GPNPHLCG_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GPNPHLCG_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
GPNPHLCG_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GPNPHLCG_00132 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GPNPHLCG_00133 1.6e-177 ybaC 3.4.11.5 S Alpha/beta hydrolase family
GPNPHLCG_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
GPNPHLCG_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GPNPHLCG_00136 3.9e-105 rplD J Forms part of the polypeptide exit tunnel
GPNPHLCG_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
GPNPHLCG_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GPNPHLCG_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GPNPHLCG_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GPNPHLCG_00141 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GPNPHLCG_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GPNPHLCG_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
GPNPHLCG_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GPNPHLCG_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GPNPHLCG_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GPNPHLCG_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GPNPHLCG_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPNPHLCG_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GPNPHLCG_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GPNPHLCG_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GPNPHLCG_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GPNPHLCG_00153 1.9e-23 rpmD J Ribosomal protein L30
GPNPHLCG_00154 1.8e-72 rplO J binds to the 23S rRNA
GPNPHLCG_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
GPNPHLCG_00156 4.8e-122 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
GPNPHLCG_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
GPNPHLCG_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GPNPHLCG_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
GPNPHLCG_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GPNPHLCG_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GPNPHLCG_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GPNPHLCG_00163 3.6e-58 rplQ J Ribosomal protein L17
GPNPHLCG_00164 1.5e-155 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNPHLCG_00165 2.4e-153 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNPHLCG_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GPNPHLCG_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
GPNPHLCG_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GPNPHLCG_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
GPNPHLCG_00170 1.2e-143 ybaJ Q Methyltransferase domain
GPNPHLCG_00171 3.5e-71 ybaK S Protein of unknown function (DUF2521)
GPNPHLCG_00172 2.8e-131 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNPHLCG_00173 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
GPNPHLCG_00174 1.2e-84 gerD
GPNPHLCG_00175 3.9e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
GPNPHLCG_00176 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
GPNPHLCG_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00180 2e-08
GPNPHLCG_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00185 9.9e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00187 2.5e-248 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
GPNPHLCG_00189 2.6e-148 ybaS 1.1.1.58 S Na -dependent transporter
GPNPHLCG_00190 1.1e-138 ybbA S Putative esterase
GPNPHLCG_00191 2.1e-177 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00192 2e-175 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00193 1.4e-165 feuA P Iron-uptake system-binding protein
GPNPHLCG_00194 2.8e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
GPNPHLCG_00195 3.5e-238 ybbC 3.2.1.52 S protein conserved in bacteria
GPNPHLCG_00196 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
GPNPHLCG_00197 5.9e-252 yfeW 3.4.16.4 V Belongs to the UPF0214 family
GPNPHLCG_00198 6.4e-233 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_00199 1.4e-150 ybbH K transcriptional
GPNPHLCG_00200 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GPNPHLCG_00201 2.2e-28 ybbJ J acetyltransferase
GPNPHLCG_00202 1.6e-76 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
GPNPHLCG_00208 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_00209 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
GPNPHLCG_00210 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPNPHLCG_00211 9.8e-224 ybbR S protein conserved in bacteria
GPNPHLCG_00212 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GPNPHLCG_00213 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
GPNPHLCG_00214 5.1e-124 tnsA L TnsA endonuclease N terminal
GPNPHLCG_00215 0.0 tnsB L Mu transposase, C-terminal
GPNPHLCG_00216 3.2e-258 L Bacterial TniB protein
GPNPHLCG_00217 3.5e-290 tnsD L Tn7-like transposition protein D
GPNPHLCG_00218 7.6e-243
GPNPHLCG_00219 1.7e-215 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNPHLCG_00220 4.3e-39
GPNPHLCG_00221 5.7e-175 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_00223 8.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPNPHLCG_00224 7.2e-36 adaA 3.2.2.21 K Transcriptional regulator
GPNPHLCG_00225 3e-37 adaA 3.2.2.21 K Transcriptional regulator
GPNPHLCG_00226 1.5e-100 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPNPHLCG_00227 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GPNPHLCG_00228 0.0 ybcC S Belongs to the UPF0753 family
GPNPHLCG_00229 1.5e-92 can 4.2.1.1 P carbonic anhydrase
GPNPHLCG_00231 1.9e-46
GPNPHLCG_00232 1.8e-60 ybcI S Uncharacterized conserved protein (DUF2294)
GPNPHLCG_00233 5.1e-50 ybzH K Helix-turn-helix domain
GPNPHLCG_00234 4.5e-203 ybcL EGP Major facilitator Superfamily
GPNPHLCG_00235 1.2e-55
GPNPHLCG_00236 4.5e-180 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GPNPHLCG_00237 1.3e-122 T Transcriptional regulatory protein, C terminal
GPNPHLCG_00238 2.2e-171 T His Kinase A (phospho-acceptor) domain
GPNPHLCG_00240 3.9e-139 KLT Protein tyrosine kinase
GPNPHLCG_00241 7.7e-152 ybdN
GPNPHLCG_00242 2.4e-212 ybdO S Domain of unknown function (DUF4885)
GPNPHLCG_00243 8.4e-257 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_00244 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
GPNPHLCG_00245 4.9e-30 ybxH S Family of unknown function (DUF5370)
GPNPHLCG_00246 7.5e-149 ybxI 3.5.2.6 V beta-lactamase
GPNPHLCG_00247 1.7e-245 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
GPNPHLCG_00248 4.9e-41 ybyB
GPNPHLCG_00249 3e-290 ybeC E amino acid
GPNPHLCG_00250 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00251 1.4e-45 L transposase activity
GPNPHLCG_00252 4.9e-162 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNPHLCG_00253 7.3e-258 glpT G -transporter
GPNPHLCG_00254 8.5e-35 S Protein of unknown function (DUF2651)
GPNPHLCG_00255 3.3e-153 ybfA 3.4.15.5 K FR47-like protein
GPNPHLCG_00256 1e-221 ybfB G COG0477 Permeases of the major facilitator superfamily
GPNPHLCG_00258 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
GPNPHLCG_00259 4.4e-161 ybfH EG EamA-like transporter family
GPNPHLCG_00260 8.2e-143 msmR K AraC-like ligand binding domain
GPNPHLCG_00261 9.9e-211 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
GPNPHLCG_00262 1.1e-175 mpr 3.4.21.19 M Belongs to the peptidase S1B family
GPNPHLCG_00264 7e-164 S Alpha/beta hydrolase family
GPNPHLCG_00265 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPNPHLCG_00266 2.7e-85 ybfM S SNARE associated Golgi protein
GPNPHLCG_00267 2.4e-147 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
GPNPHLCG_00268 3e-44 ybfN
GPNPHLCG_00269 1.5e-191 yceA S Belongs to the UPF0176 family
GPNPHLCG_00270 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNPHLCG_00271 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_00272 5.7e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPNPHLCG_00273 3.1e-128 K UTRA
GPNPHLCG_00275 3.6e-202 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPNPHLCG_00276 1.7e-260 mmuP E amino acid
GPNPHLCG_00277 1.1e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
GPNPHLCG_00278 6.2e-255 agcS E Sodium alanine symporter
GPNPHLCG_00279 3.8e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
GPNPHLCG_00280 3.2e-84 phoQ 2.7.13.3 T Histidine kinase
GPNPHLCG_00281 1.5e-18 phoQ 2.7.13.3 T Histidine kinase
GPNPHLCG_00282 3.9e-78 phoQ 2.7.13.3 T Histidine kinase
GPNPHLCG_00283 2.6e-169 glnL T Regulator
GPNPHLCG_00284 1e-173 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
GPNPHLCG_00285 2e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNPHLCG_00286 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
GPNPHLCG_00287 9.4e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNPHLCG_00288 2.1e-123 ycbG K FCD
GPNPHLCG_00289 5.6e-183 garD 4.2.1.42, 4.2.1.7 G Altronate
GPNPHLCG_00290 2.4e-77 garD 4.2.1.42, 4.2.1.7 G Altronate
GPNPHLCG_00291 1.3e-176 ycbJ S Macrolide 2'-phosphotransferase
GPNPHLCG_00292 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
GPNPHLCG_00293 9.9e-169 eamA1 EG spore germination
GPNPHLCG_00294 6.5e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_00295 2.2e-168 T PhoQ Sensor
GPNPHLCG_00296 3.1e-167 ycbN V ABC transporter, ATP-binding protein
GPNPHLCG_00297 5.6e-113 S ABC-2 family transporter protein
GPNPHLCG_00298 1.3e-50 ycbP S Protein of unknown function (DUF2512)
GPNPHLCG_00299 3.4e-76 sleB 3.5.1.28 M Cell wall
GPNPHLCG_00300 3.3e-135 ycbR T vWA found in TerF C terminus
GPNPHLCG_00301 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
GPNPHLCG_00302 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GPNPHLCG_00303 3.5e-118 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPNPHLCG_00304 3.2e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GPNPHLCG_00305 3.9e-204 ycbU E Selenocysteine lyase
GPNPHLCG_00306 1.8e-230 lmrB EGP the major facilitator superfamily
GPNPHLCG_00307 3.1e-101 yxaF K Transcriptional regulator
GPNPHLCG_00308 1.9e-198 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
GPNPHLCG_00309 1.6e-114 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPNPHLCG_00310 4.6e-56 S RDD family
GPNPHLCG_00311 2.3e-198 yccF K DNA-templated transcriptional preinitiation complex assembly
GPNPHLCG_00312 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00313 1.4e-45 L transposase activity
GPNPHLCG_00314 4.1e-126 2.7.13.3 T GHKL domain
GPNPHLCG_00315 2.2e-93 lytR_2 T LytTr DNA-binding domain
GPNPHLCG_00316 5.8e-178 natB CP ABC-2 family transporter protein
GPNPHLCG_00317 2.5e-172 yccK C Aldo keto reductase
GPNPHLCG_00318 2.5e-176 ycdA S Domain of unknown function (DUF5105)
GPNPHLCG_00319 2.3e-270 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_00320 1.5e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_00321 7.3e-94 cwlK M D-alanyl-D-alanine carboxypeptidase
GPNPHLCG_00322 5.7e-171 S response regulator aspartate phosphatase
GPNPHLCG_00323 2.3e-139 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_00324 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
GPNPHLCG_00325 4.3e-167 adcA P Belongs to the bacterial solute-binding protein 9 family
GPNPHLCG_00326 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPNPHLCG_00327 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPNPHLCG_00328 4.7e-185 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_00329 2.1e-108 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
GPNPHLCG_00330 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
GPNPHLCG_00331 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
GPNPHLCG_00332 6.3e-137 terC P Protein of unknown function (DUF475)
GPNPHLCG_00333 0.0 yceG S Putative component of 'biosynthetic module'
GPNPHLCG_00334 2e-192 yceH P Belongs to the TelA family
GPNPHLCG_00335 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
GPNPHLCG_00336 5.8e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
GPNPHLCG_00337 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
GPNPHLCG_00338 2.5e-228 proV 3.6.3.32 E glycine betaine
GPNPHLCG_00339 1.3e-127 opuAB P glycine betaine
GPNPHLCG_00340 4.5e-163 opuAC E glycine betaine
GPNPHLCG_00341 5.4e-217 amhX S amidohydrolase
GPNPHLCG_00342 2.5e-256 ycgA S Membrane
GPNPHLCG_00343 1.4e-78 ycgB
GPNPHLCG_00344 1.8e-270 amyE 3.2.1.1 GH13 G alpha-amylase
GPNPHLCG_00345 9.2e-98 amyE 3.2.1.1 GH13 G alpha-amylase
GPNPHLCG_00346 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
GPNPHLCG_00347 2e-289 lctP C L-lactate permease
GPNPHLCG_00348 1.2e-148 yqcI S YqcI/YcgG family
GPNPHLCG_00349 1.2e-152 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_00350 1.2e-93 ycgI S Domain of unknown function (DUF1989)
GPNPHLCG_00351 1.7e-148 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
GPNPHLCG_00352 2.6e-86 tmrB S AAA domain
GPNPHLCG_00353 6.7e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GPNPHLCG_00354 2.2e-142 yafE Q ubiE/COQ5 methyltransferase family
GPNPHLCG_00355 2.2e-179 oxyR3 K LysR substrate binding domain
GPNPHLCG_00356 1.5e-183 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
GPNPHLCG_00357 2.9e-145 ycgL S Predicted nucleotidyltransferase
GPNPHLCG_00358 5.1e-170 ycgM E Proline dehydrogenase
GPNPHLCG_00359 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GPNPHLCG_00360 8.9e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_00361 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
GPNPHLCG_00362 2.6e-147 ycgQ S membrane
GPNPHLCG_00363 1.2e-139 ycgR S permeases
GPNPHLCG_00364 8.6e-159 I alpha/beta hydrolase fold
GPNPHLCG_00365 4e-192 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
GPNPHLCG_00366 3.9e-273 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPNPHLCG_00367 1.7e-56 nirD 1.7.1.15 P Nitrite reductase
GPNPHLCG_00368 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GPNPHLCG_00369 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNPHLCG_00370 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
GPNPHLCG_00371 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
GPNPHLCG_00372 8.7e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
GPNPHLCG_00373 1e-107 yciB M ErfK YbiS YcfS YnhG
GPNPHLCG_00374 5e-226 yciC S GTPases (G3E family)
GPNPHLCG_00375 3.5e-115 yecS P COG0765 ABC-type amino acid transport system, permease component
GPNPHLCG_00376 1.5e-131 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
GPNPHLCG_00378 3.7e-42 yckC S membrane
GPNPHLCG_00379 7.8e-52 yckD S Protein of unknown function (DUF2680)
GPNPHLCG_00380 1.2e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNPHLCG_00381 8.5e-69 nin S Competence protein J (ComJ)
GPNPHLCG_00382 5.6e-69 nucA M Deoxyribonuclease NucA/NucB
GPNPHLCG_00383 1.4e-176 tlpC 2.7.13.3 NT chemotaxis protein
GPNPHLCG_00384 1.9e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
GPNPHLCG_00385 4e-105 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
GPNPHLCG_00386 1.3e-63 hxlR K transcriptional
GPNPHLCG_00387 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_00388 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_00389 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
GPNPHLCG_00390 2.2e-139 srfAD Q thioesterase
GPNPHLCG_00391 1.5e-225 EGP Major Facilitator Superfamily
GPNPHLCG_00392 4.8e-86 S YcxB-like protein
GPNPHLCG_00393 5.8e-161 ycxC EG EamA-like transporter family
GPNPHLCG_00394 6.2e-249 ycxD K GntR family transcriptional regulator
GPNPHLCG_00395 1.2e-112 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
GPNPHLCG_00396 1.7e-114 yczE S membrane
GPNPHLCG_00397 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNPHLCG_00398 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
GPNPHLCG_00399 4.4e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
GPNPHLCG_00400 4.9e-162 bsdA K LysR substrate binding domain
GPNPHLCG_00401 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
GPNPHLCG_00402 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
GPNPHLCG_00403 4e-39 bsdD 4.1.1.61 S response to toxic substance
GPNPHLCG_00404 2.7e-82 yclD
GPNPHLCG_00405 8.4e-159 yclE 3.4.11.5 S Alpha beta hydrolase
GPNPHLCG_00406 7.3e-267 dtpT E amino acid peptide transporter
GPNPHLCG_00407 5.9e-292 yclG M Pectate lyase superfamily protein
GPNPHLCG_00409 7.8e-278 gerKA EG Spore germination protein
GPNPHLCG_00410 4e-226 gerKC S spore germination
GPNPHLCG_00411 1.3e-194 gerKB F Spore germination protein
GPNPHLCG_00412 7.3e-121 yclH P ABC transporter
GPNPHLCG_00413 4e-201 yclI V ABC transporter (permease) YclI
GPNPHLCG_00414 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_00415 1.3e-260 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
GPNPHLCG_00416 3.1e-71 S aspartate phosphatase
GPNPHLCG_00420 2.8e-241 lysC 2.7.2.4 E Belongs to the aspartokinase family
GPNPHLCG_00421 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00422 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00423 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
GPNPHLCG_00424 8.5e-168 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
GPNPHLCG_00425 9.2e-251 ycnB EGP Major facilitator Superfamily
GPNPHLCG_00426 5.5e-153 ycnC K Transcriptional regulator
GPNPHLCG_00427 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
GPNPHLCG_00428 1.6e-45 ycnE S Monooxygenase
GPNPHLCG_00429 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
GPNPHLCG_00430 1.1e-272 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_00431 1.4e-245 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNPHLCG_00432 1.1e-264 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNPHLCG_00433 6.1e-149 glcU U Glucose uptake
GPNPHLCG_00434 1.4e-144 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_00435 6.6e-97 ycnI S protein conserved in bacteria
GPNPHLCG_00436 1.1e-305 ycnJ P protein, homolog of Cu resistance protein CopC
GPNPHLCG_00437 1.6e-105 ycnK K COG1349 Transcriptional regulators of sugar metabolism
GPNPHLCG_00438 7.3e-56
GPNPHLCG_00439 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
GPNPHLCG_00440 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
GPNPHLCG_00441 3.4e-208 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
GPNPHLCG_00442 1.1e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
GPNPHLCG_00443 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPNPHLCG_00444 1.2e-73 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPNPHLCG_00445 8.8e-110 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
GPNPHLCG_00446 3.5e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
GPNPHLCG_00448 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
GPNPHLCG_00449 3.6e-140 ycsF S Belongs to the UPF0271 (lamB) family
GPNPHLCG_00450 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
GPNPHLCG_00451 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
GPNPHLCG_00452 1.6e-134 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
GPNPHLCG_00453 1.4e-184 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
GPNPHLCG_00454 3.9e-131 kipR K Transcriptional regulator
GPNPHLCG_00455 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
GPNPHLCG_00457 1.4e-49 yczJ S biosynthesis
GPNPHLCG_00458 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
GPNPHLCG_00459 8.3e-173 ydhF S Oxidoreductase
GPNPHLCG_00460 0.0 mtlR K transcriptional regulator, MtlR
GPNPHLCG_00461 3.3e-291 ydaB IQ acyl-CoA ligase
GPNPHLCG_00462 2e-98 ydaC Q Methyltransferase domain
GPNPHLCG_00463 2e-160 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_00464 5.5e-89 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
GPNPHLCG_00465 1.4e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPNPHLCG_00466 6.8e-77 ydaG 1.4.3.5 S general stress protein
GPNPHLCG_00467 9.2e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
GPNPHLCG_00468 3.6e-45 ydzA EGP Major facilitator Superfamily
GPNPHLCG_00469 2.5e-74 lrpC K Transcriptional regulator
GPNPHLCG_00470 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPNPHLCG_00471 2.4e-92 L Integrase core domain
GPNPHLCG_00472 1.4e-45 L transposase activity
GPNPHLCG_00473 8.1e-207 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
GPNPHLCG_00474 1.2e-89 ydaK T Diguanylate cyclase, GGDEF domain
GPNPHLCG_00475 3.9e-30 ydaK T Diguanylate cyclase, GGDEF domain
GPNPHLCG_00476 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
GPNPHLCG_00477 2e-203 ydaM M Glycosyl transferase family group 2
GPNPHLCG_00479 4.7e-39
GPNPHLCG_00480 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
GPNPHLCG_00482 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
GPNPHLCG_00483 2.7e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
GPNPHLCG_00485 2.6e-58 ydbB G Cupin domain
GPNPHLCG_00486 4.5e-61 ydbC S Domain of unknown function (DUF4937
GPNPHLCG_00487 1.2e-138 ydbD P Catalase
GPNPHLCG_00488 3.9e-198 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
GPNPHLCG_00489 8.1e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNPHLCG_00490 6.8e-119 dctR T COG4565 Response regulator of citrate malate metabolism
GPNPHLCG_00491 3.1e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNPHLCG_00492 9.7e-181 ydbI S AI-2E family transporter
GPNPHLCG_00493 1.8e-170 ydbJ V ABC transporter, ATP-binding protein
GPNPHLCG_00494 2.1e-124 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPNPHLCG_00495 2.7e-52 ydbL
GPNPHLCG_00496 4.8e-218 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
GPNPHLCG_00497 1.1e-18 S Fur-regulated basic protein B
GPNPHLCG_00498 2.2e-07 S Fur-regulated basic protein A
GPNPHLCG_00499 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPNPHLCG_00500 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPNPHLCG_00501 5.6e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
GPNPHLCG_00502 5.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
GPNPHLCG_00503 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
GPNPHLCG_00504 2.1e-82 ydbS S Bacterial PH domain
GPNPHLCG_00505 8.6e-260 ydbT S Membrane
GPNPHLCG_00506 9e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
GPNPHLCG_00507 8e-58 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
GPNPHLCG_00508 8.5e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
GPNPHLCG_00509 4.3e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPNPHLCG_00510 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
GPNPHLCG_00511 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
GPNPHLCG_00512 1.3e-143 rsbR T Positive regulator of sigma-B
GPNPHLCG_00513 5.2e-57 rsbS T antagonist
GPNPHLCG_00514 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
GPNPHLCG_00515 7.1e-189 rsbU 3.1.3.3 KT phosphatase
GPNPHLCG_00516 3e-51 rsbV T Belongs to the anti-sigma-factor antagonist family
GPNPHLCG_00517 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
GPNPHLCG_00518 1.1e-136 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_00519 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
GPNPHLCG_00520 0.0 yhgF K COG2183 Transcriptional accessory protein
GPNPHLCG_00521 1.7e-81 ydcK S Belongs to the SprT family
GPNPHLCG_00529 1.6e-210 L Belongs to the 'phage' integrase family
GPNPHLCG_00530 1.3e-90 immA E IrrE N-terminal-like domain
GPNPHLCG_00531 4.3e-62 yvaO K Transcriptional
GPNPHLCG_00532 1.1e-16
GPNPHLCG_00533 1.1e-40
GPNPHLCG_00535 5.1e-63 S Bacterial protein of unknown function (DUF961)
GPNPHLCG_00536 5.1e-273 ydcQ D Ftsk spoiiie family protein
GPNPHLCG_00537 8.5e-201 nicK L Replication initiation factor
GPNPHLCG_00538 4e-16 S Domain of Unknown Function with PDB structure (DUF3850)
GPNPHLCG_00541 7e-47 yddA
GPNPHLCG_00542 1.4e-166 yddB S Conjugative transposon protein TcpC
GPNPHLCG_00543 5.1e-40 yddC
GPNPHLCG_00544 4.2e-92 yddD S TcpE family
GPNPHLCG_00545 0.0 yddE S AAA-like domain
GPNPHLCG_00546 2e-55 S Domain of unknown function (DUF1874)
GPNPHLCG_00547 0.0 yddG S maturation of SSU-rRNA
GPNPHLCG_00548 1.7e-187 yddH CBM50 M Lysozyme-like
GPNPHLCG_00549 1.5e-83 yddI
GPNPHLCG_00550 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
GPNPHLCG_00551 8.8e-74 S response regulator aspartate phosphatase
GPNPHLCG_00553 3.1e-55
GPNPHLCG_00554 3.2e-114 yecA E amino acid
GPNPHLCG_00555 5.3e-103 K Transcriptional regulator
GPNPHLCG_00556 2.5e-74 rimJ2 J Acetyltransferase (GNAT) domain
GPNPHLCG_00557 8.5e-45
GPNPHLCG_00558 2.3e-33 S LXG domain of WXG superfamily
GPNPHLCG_00559 2.8e-68 L HNH nucleases
GPNPHLCG_00563 8e-10
GPNPHLCG_00565 3.4e-33 K Helix-turn-helix XRE-family like proteins
GPNPHLCG_00566 4.6e-42
GPNPHLCG_00567 5.4e-192 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GPNPHLCG_00569 8.7e-30 cspL K Cold shock
GPNPHLCG_00570 4.1e-63 carD K Transcription factor
GPNPHLCG_00571 7.5e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GPNPHLCG_00572 4.4e-163 rhaS5 K AraC-like ligand binding domain
GPNPHLCG_00573 1.7e-171 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
GPNPHLCG_00574 1.8e-164 ydeE K AraC family transcriptional regulator
GPNPHLCG_00575 4.3e-261 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_00576 7.9e-217 ydeG EGP Major facilitator superfamily
GPNPHLCG_00577 1.4e-44 ydeH
GPNPHLCG_00578 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
GPNPHLCG_00579 4.3e-110
GPNPHLCG_00580 1.1e-31 S SNARE associated Golgi protein
GPNPHLCG_00581 1.8e-14 ptsH G PTS HPr component phosphorylation site
GPNPHLCG_00582 2.3e-85 K Transcriptional regulator C-terminal region
GPNPHLCG_00583 4.1e-153 ydeK EG -transporter
GPNPHLCG_00584 1.6e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_00585 4.2e-74 maoC I N-terminal half of MaoC dehydratase
GPNPHLCG_00586 2.5e-106 ydeN S Serine hydrolase
GPNPHLCG_00587 6.8e-56 K HxlR-like helix-turn-helix
GPNPHLCG_00588 5.4e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPNPHLCG_00589 7.7e-68 ydeP K Transcriptional regulator
GPNPHLCG_00590 3.7e-32 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
GPNPHLCG_00591 1.6e-48 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
GPNPHLCG_00592 8.1e-192 ydeR EGP Major facilitator Superfamily
GPNPHLCG_00593 2.1e-103 ydeS K Transcriptional regulator
GPNPHLCG_00594 2.8e-57 arsR K transcriptional
GPNPHLCG_00595 2.8e-230 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPNPHLCG_00596 1.1e-71 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
GPNPHLCG_00597 2.1e-148 ydfB J GNAT acetyltransferase
GPNPHLCG_00598 2.1e-155 ydfC EG EamA-like transporter family
GPNPHLCG_00599 2.3e-273 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_00600 1.3e-113 ydfE S Flavin reductase like domain
GPNPHLCG_00601 1e-122 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
GPNPHLCG_00602 3.4e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPNPHLCG_00604 2.7e-176 ydfH 2.7.13.3 T Histidine kinase
GPNPHLCG_00605 3.5e-109 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_00606 0.0 ydfJ S drug exporters of the RND superfamily
GPNPHLCG_00607 1.4e-175 S Alpha/beta hydrolase family
GPNPHLCG_00608 8.5e-117 S Protein of unknown function (DUF554)
GPNPHLCG_00609 1.9e-144 K Bacterial transcription activator, effector binding domain
GPNPHLCG_00611 5.6e-11 S response regulator aspartate phosphatase
GPNPHLCG_00612 5.4e-13
GPNPHLCG_00615 5.1e-58 L COG3666 Transposase and inactivated derivatives
GPNPHLCG_00616 2.9e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPNPHLCG_00617 9.6e-112 ydfN C nitroreductase
GPNPHLCG_00618 6.8e-186 ydfO E COG0346 Lactoylglutathione lyase and related lyases
GPNPHLCG_00619 8.8e-63 mhqP S DoxX
GPNPHLCG_00620 1.7e-54 traF CO Thioredoxin
GPNPHLCG_00621 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
GPNPHLCG_00622 6.3e-29
GPNPHLCG_00624 1.9e-99 ydfR S Protein of unknown function (DUF421)
GPNPHLCG_00625 7.6e-121 ydfS S Protein of unknown function (DUF421)
GPNPHLCG_00626 7.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
GPNPHLCG_00627 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
GPNPHLCG_00628 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
GPNPHLCG_00629 1.7e-98 K Bacterial regulatory proteins, tetR family
GPNPHLCG_00630 2.8e-52 S DoxX-like family
GPNPHLCG_00631 5e-84 yycN 2.3.1.128 K Acetyltransferase
GPNPHLCG_00632 5.1e-134 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
GPNPHLCG_00633 2e-119 purR K helix_turn _helix lactose operon repressor
GPNPHLCG_00634 4.5e-191 csbC EGP Major facilitator Superfamily
GPNPHLCG_00635 2.6e-104 G Xylose isomerase-like TIM barrel
GPNPHLCG_00636 2.7e-299 expZ S ABC transporter
GPNPHLCG_00637 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_00638 8.7e-90 dinB S DinB family
GPNPHLCG_00639 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_00640 0.0 ydgH S drug exporters of the RND superfamily
GPNPHLCG_00641 1e-113 drgA C nitroreductase
GPNPHLCG_00642 7.1e-69 ydgJ K Winged helix DNA-binding domain
GPNPHLCG_00643 2.2e-208 tcaB EGP Major facilitator Superfamily
GPNPHLCG_00644 1.2e-121 ydhB S membrane transporter protein
GPNPHLCG_00645 6.5e-122 ydhC K FCD
GPNPHLCG_00646 2.2e-243 ydhD M Glycosyl hydrolase
GPNPHLCG_00647 3.2e-225 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GPNPHLCG_00648 7.4e-124
GPNPHLCG_00649 1.5e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
GPNPHLCG_00650 1.3e-66 frataxin S Domain of unknown function (DU1801)
GPNPHLCG_00652 3.3e-83 K Acetyltransferase (GNAT) domain
GPNPHLCG_00653 1.7e-179 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
GPNPHLCG_00654 2.5e-98 ydhK M Protein of unknown function (DUF1541)
GPNPHLCG_00655 3e-199 pbuE EGP Major facilitator Superfamily
GPNPHLCG_00656 1.9e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNPHLCG_00657 3e-51 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNPHLCG_00658 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNPHLCG_00659 3.2e-280 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNPHLCG_00660 1.1e-132 ydhQ K UTRA
GPNPHLCG_00661 2e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
GPNPHLCG_00662 2.1e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPNPHLCG_00663 6.4e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
GPNPHLCG_00664 1.8e-78 ydhU P Catalase
GPNPHLCG_00665 1.1e-16 ydhU P Manganese containing catalase
GPNPHLCG_00668 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00669 7.8e-08
GPNPHLCG_00671 1.2e-180 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GPNPHLCG_00672 2.6e-85 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
GPNPHLCG_00673 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
GPNPHLCG_00674 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
GPNPHLCG_00675 3e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GPNPHLCG_00676 0.0 ydiF S ABC transporter
GPNPHLCG_00677 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
GPNPHLCG_00678 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GPNPHLCG_00679 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
GPNPHLCG_00680 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GPNPHLCG_00681 2.9e-27 ydiK S Domain of unknown function (DUF4305)
GPNPHLCG_00682 7.9e-129 ydiL S CAAX protease self-immunity
GPNPHLCG_00683 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GPNPHLCG_00684 2.2e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
GPNPHLCG_00686 2.3e-62
GPNPHLCG_00688 9.3e-59
GPNPHLCG_00689 3.8e-51
GPNPHLCG_00690 0.0 K NB-ARC domain
GPNPHLCG_00691 7.2e-200 gutB 1.1.1.14 E Dehydrogenase
GPNPHLCG_00692 5.5e-248 gutA G MFS/sugar transport protein
GPNPHLCG_00693 2e-172 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
GPNPHLCG_00694 3.3e-113 pspA KT Phage shock protein A
GPNPHLCG_00695 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPNPHLCG_00696 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
GPNPHLCG_00697 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
GPNPHLCG_00698 4.7e-196 S Ion transport 2 domain protein
GPNPHLCG_00699 2.7e-258 iolT EGP Major facilitator Superfamily
GPNPHLCG_00700 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
GPNPHLCG_00701 4.5e-64 ydjM M Lytic transglycolase
GPNPHLCG_00702 2.3e-150 ydjN U Involved in the tonB-independent uptake of proteins
GPNPHLCG_00703 1.4e-45 L transposase activity
GPNPHLCG_00704 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00706 1.4e-34 ydjO S Cold-inducible protein YdjO
GPNPHLCG_00707 8.4e-156 ydjP I Alpha/beta hydrolase family
GPNPHLCG_00708 8.8e-176 yeaA S Protein of unknown function (DUF4003)
GPNPHLCG_00709 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
GPNPHLCG_00710 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_00711 3.5e-152 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GPNPHLCG_00712 3e-176 yeaC S COG0714 MoxR-like ATPases
GPNPHLCG_00713 1.5e-222 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
GPNPHLCG_00714 0.0 yebA E COG1305 Transglutaminase-like enzymes
GPNPHLCG_00715 1.9e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
GPNPHLCG_00717 2.5e-210 pbuG S permease
GPNPHLCG_00718 2.3e-118 yebC M Membrane
GPNPHLCG_00720 4e-93 yebE S UPF0316 protein
GPNPHLCG_00721 8e-28 yebG S NETI protein
GPNPHLCG_00722 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GPNPHLCG_00723 8.5e-215 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GPNPHLCG_00724 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GPNPHLCG_00725 1.4e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
GPNPHLCG_00726 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNPHLCG_00727 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNPHLCG_00728 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GPNPHLCG_00729 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
GPNPHLCG_00730 3.8e-177 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
GPNPHLCG_00731 4.8e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GPNPHLCG_00732 2.7e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
GPNPHLCG_00733 1.1e-234 purD 6.3.4.13 F Belongs to the GARS family
GPNPHLCG_00734 3e-72 K helix_turn_helix ASNC type
GPNPHLCG_00735 4.3e-231 yjeH E Amino acid permease
GPNPHLCG_00736 2.7e-27 S Protein of unknown function (DUF2892)
GPNPHLCG_00737 0.0 yerA 3.5.4.2 F adenine deaminase
GPNPHLCG_00738 7e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
GPNPHLCG_00739 4.8e-51 yerC S protein conserved in bacteria
GPNPHLCG_00740 4.4e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
GPNPHLCG_00741 4.9e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GPNPHLCG_00742 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
GPNPHLCG_00743 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GPNPHLCG_00744 5.4e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
GPNPHLCG_00745 1.4e-45 L transposase activity
GPNPHLCG_00746 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00748 1.9e-194 yerI S homoserine kinase type II (protein kinase fold)
GPNPHLCG_00749 1.6e-123 sapB S MgtC SapB transporter
GPNPHLCG_00750 7.1e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_00751 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPNPHLCG_00752 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
GPNPHLCG_00753 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GPNPHLCG_00754 1.3e-148 yerO K Transcriptional regulator
GPNPHLCG_00755 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GPNPHLCG_00756 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPNPHLCG_00757 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPNPHLCG_00759 3.7e-101 S response regulator aspartate phosphatase
GPNPHLCG_00762 2.7e-82 S Protein of unknown function, DUF600
GPNPHLCG_00763 0.0 L nucleic acid phosphodiester bond hydrolysis
GPNPHLCG_00765 7.3e-100 L endonuclease activity
GPNPHLCG_00766 5.7e-49
GPNPHLCG_00767 1.6e-210 S Tetratricopeptide repeat
GPNPHLCG_00769 2.7e-126 yeeN K transcriptional regulatory protein
GPNPHLCG_00771 6.7e-99 dhaR3 K Transcriptional regulator
GPNPHLCG_00772 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
GPNPHLCG_00773 1.5e-45 cotJB S CotJB protein
GPNPHLCG_00774 2e-103 cotJC P Spore Coat
GPNPHLCG_00775 6e-102 yesJ K Acetyltransferase (GNAT) family
GPNPHLCG_00777 5e-100 yesL S Protein of unknown function, DUF624
GPNPHLCG_00778 0.0 yesM 2.7.13.3 T Histidine kinase
GPNPHLCG_00779 6.3e-199 yesN K helix_turn_helix, arabinose operon control protein
GPNPHLCG_00780 6.2e-246 yesO G Bacterial extracellular solute-binding protein
GPNPHLCG_00781 8.9e-170 yesP G Binding-protein-dependent transport system inner membrane component
GPNPHLCG_00782 5.7e-37 yesQ P Binding-protein-dependent transport system inner membrane component
GPNPHLCG_00783 1.2e-83 yesQ P Binding-protein-dependent transport system inner membrane component
GPNPHLCG_00784 1.1e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
GPNPHLCG_00785 3.5e-247 yesS K Transcriptional regulator
GPNPHLCG_00786 9.8e-158 yesS K Transcriptional regulator
GPNPHLCG_00787 2.7e-131 E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_00788 1.2e-128 yesU S Domain of unknown function (DUF1961)
GPNPHLCG_00789 5.7e-112 yesV S Protein of unknown function, DUF624
GPNPHLCG_00790 1.5e-55 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
GPNPHLCG_00791 1.3e-45 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
GPNPHLCG_00792 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
GPNPHLCG_00793 2e-123 yesY E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_00794 7.1e-225 yesZ 3.2.1.23 G beta-galactosidase activity
GPNPHLCG_00795 6.5e-156 yesZ 3.2.1.23 G beta-galactosidase activity
GPNPHLCG_00796 0.0 yetA
GPNPHLCG_00797 2.4e-289 lplA G Bacterial extracellular solute-binding protein
GPNPHLCG_00798 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
GPNPHLCG_00799 3.2e-161 lplC G Binding-protein-dependent transport system inner membrane component
GPNPHLCG_00800 1.3e-251 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GPNPHLCG_00801 6.7e-122 yetF S membrane
GPNPHLCG_00802 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
GPNPHLCG_00803 2.6e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNPHLCG_00804 2.2e-34
GPNPHLCG_00805 1.2e-144 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPNPHLCG_00806 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
GPNPHLCG_00807 1.2e-104 yetJ S Belongs to the BI1 family
GPNPHLCG_00808 1.2e-41 yetL K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_00809 3.3e-28 yetM CH FAD binding domain
GPNPHLCG_00810 2.3e-198 yetN S Protein of unknown function (DUF3900)
GPNPHLCG_00811 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GPNPHLCG_00812 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNPHLCG_00813 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
GPNPHLCG_00814 1.9e-186 yfnG 4.2.1.45 M dehydratase
GPNPHLCG_00815 7.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
GPNPHLCG_00816 1.1e-222 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
GPNPHLCG_00817 2.8e-187 yfnD M Nucleotide-diphospho-sugar transferase
GPNPHLCG_00818 4.6e-206 fsr P COG0477 Permeases of the major facilitator superfamily
GPNPHLCG_00819 7.6e-82 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
GPNPHLCG_00820 2.4e-240 yfnA E amino acid
GPNPHLCG_00821 1.1e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNPHLCG_00822 1.1e-113 yfmS NT chemotaxis protein
GPNPHLCG_00823 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPNPHLCG_00824 5.7e-74 yfmQ S Uncharacterised protein from bacillus cereus group
GPNPHLCG_00825 1.4e-69 yfmP K transcriptional
GPNPHLCG_00826 1.9e-209 yfmO EGP Major facilitator Superfamily
GPNPHLCG_00827 2.7e-296 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPNPHLCG_00828 5e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
GPNPHLCG_00829 1.8e-75 yfmK 2.3.1.128 K acetyltransferase
GPNPHLCG_00830 7.2e-189 yfmJ S N-terminal domain of oxidoreductase
GPNPHLCG_00831 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
GPNPHLCG_00832 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00833 1.2e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00834 2.3e-165 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
GPNPHLCG_00835 5e-24 S Protein of unknown function (DUF3212)
GPNPHLCG_00836 7.6e-58 yflT S Heat induced stress protein YflT
GPNPHLCG_00837 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
GPNPHLCG_00838 5.5e-235 yflS P Sodium:sulfate symporter transmembrane region
GPNPHLCG_00839 3.7e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNPHLCG_00840 1.3e-117 citT T response regulator
GPNPHLCG_00841 1.4e-178 yflP S Tripartite tricarboxylate transporter family receptor
GPNPHLCG_00842 3.2e-226 citM C Citrate transporter
GPNPHLCG_00843 1e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNPHLCG_00844 1.3e-215 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
GPNPHLCG_00845 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
GPNPHLCG_00846 5.1e-19 yflK S protein conserved in bacteria
GPNPHLCG_00847 7.1e-46 yflK S protein conserved in bacteria
GPNPHLCG_00848 8.9e-18 yflJ S Protein of unknown function (DUF2639)
GPNPHLCG_00849 4.1e-19 yflI
GPNPHLCG_00850 4.5e-49 yflH S Protein of unknown function (DUF3243)
GPNPHLCG_00851 2.1e-137 map 3.4.11.18 E Methionine aminopeptidase
GPNPHLCG_00852 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
GPNPHLCG_00853 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNPHLCG_00854 3.9e-66 yhdN S Domain of unknown function (DUF1992)
GPNPHLCG_00855 2.3e-126 yfkQ EG Spore germination protein
GPNPHLCG_00856 5.5e-256 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_00857 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
GPNPHLCG_00858 1.8e-133 treR K transcriptional
GPNPHLCG_00859 1.5e-123 yfkO C nitroreductase
GPNPHLCG_00860 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
GPNPHLCG_00861 4.3e-89 yfkM 1.11.1.6, 3.5.1.124 S protease
GPNPHLCG_00862 1.5e-206 ydiM EGP Major facilitator Superfamily
GPNPHLCG_00863 1.3e-28 yfkK S Belongs to the UPF0435 family
GPNPHLCG_00864 1.9e-83 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPNPHLCG_00865 2.4e-50 yfkI S gas vesicle protein
GPNPHLCG_00866 1.3e-143 yihY S Belongs to the UPF0761 family
GPNPHLCG_00867 5e-08
GPNPHLCG_00868 1.5e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
GPNPHLCG_00869 6.1e-183 cax P COG0387 Ca2 H antiporter
GPNPHLCG_00870 1.2e-146 yfkD S YfkD-like protein
GPNPHLCG_00871 6e-149 yfkC M Mechanosensitive ion channel
GPNPHLCG_00872 2.1e-221 yfkA S YfkB-like domain
GPNPHLCG_00873 1.1e-26 yfjT
GPNPHLCG_00874 7.6e-154 pdaA G deacetylase
GPNPHLCG_00875 1.5e-147 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
GPNPHLCG_00876 5e-184 corA P Mediates influx of magnesium ions
GPNPHLCG_00877 5.2e-164 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
GPNPHLCG_00878 5.3e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GPNPHLCG_00879 2e-43 S YfzA-like protein
GPNPHLCG_00880 7.1e-186 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GPNPHLCG_00881 1.9e-85 yfjM S Psort location Cytoplasmic, score
GPNPHLCG_00882 2.3e-29 yfjL
GPNPHLCG_00883 2.2e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNPHLCG_00884 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNPHLCG_00885 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNPHLCG_00886 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPNPHLCG_00887 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
GPNPHLCG_00888 1.2e-25 sspH S Belongs to the SspH family
GPNPHLCG_00889 4e-56 yfjF S UPF0060 membrane protein
GPNPHLCG_00890 2.4e-98 yfjD S Family of unknown function (DUF5381)
GPNPHLCG_00891 9e-144 yfjC
GPNPHLCG_00892 2.7e-190 yfjB
GPNPHLCG_00893 1.1e-44 yfjA S Belongs to the WXG100 family
GPNPHLCG_00894 2.4e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNPHLCG_00895 4.6e-140 glvR K Helix-turn-helix domain, rpiR family
GPNPHLCG_00896 1e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_00897 2.9e-307 yfiB3 V ABC transporter
GPNPHLCG_00898 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNPHLCG_00899 6.4e-64 mhqP S DoxX
GPNPHLCG_00900 5.7e-163 yfiE 1.13.11.2 S glyoxalase
GPNPHLCG_00901 3e-173 K AraC-like ligand binding domain
GPNPHLCG_00902 3.2e-259 iolT EGP Major facilitator Superfamily
GPNPHLCG_00903 3.2e-183 G Xylose isomerase
GPNPHLCG_00904 1.1e-230 S Oxidoreductase
GPNPHLCG_00906 1.8e-212 yxjM T Histidine kinase
GPNPHLCG_00907 5.4e-113 KT LuxR family transcriptional regulator
GPNPHLCG_00908 1.5e-169 V ABC transporter, ATP-binding protein
GPNPHLCG_00909 5e-210 V ABC-2 family transporter protein
GPNPHLCG_00910 1.3e-207 V COG0842 ABC-type multidrug transport system, permease component
GPNPHLCG_00911 8.3e-99 padR K transcriptional
GPNPHLCG_00912 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
GPNPHLCG_00913 2.2e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
GPNPHLCG_00914 5.4e-107 yfiR K Transcriptional regulator
GPNPHLCG_00915 6.3e-195 yfiS EGP Major facilitator Superfamily
GPNPHLCG_00916 4.7e-99 yfiT S Belongs to the metal hydrolase YfiT family
GPNPHLCG_00917 1.4e-281 yfiU EGP Major facilitator Superfamily
GPNPHLCG_00918 4.9e-79 yfiV K transcriptional
GPNPHLCG_00919 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GPNPHLCG_00920 5.7e-175 yfiY P ABC transporter substrate-binding protein
GPNPHLCG_00921 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00922 6.8e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_00923 2.8e-94 yfhB 5.3.3.17 S PhzF family
GPNPHLCG_00924 2.2e-60 yfhB 5.3.3.17 S PhzF family
GPNPHLCG_00925 3.9e-107 yfhC C nitroreductase
GPNPHLCG_00926 2.1e-25 yfhD S YfhD-like protein
GPNPHLCG_00928 1.2e-171 yfhF S nucleoside-diphosphate sugar epimerase
GPNPHLCG_00929 4.3e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
GPNPHLCG_00930 9.7e-52 yfhH S Protein of unknown function (DUF1811)
GPNPHLCG_00932 1.6e-208 yfhI EGP Major facilitator Superfamily
GPNPHLCG_00933 6.2e-20 sspK S reproduction
GPNPHLCG_00934 1.3e-44 yfhJ S WVELL protein
GPNPHLCG_00935 1.4e-45 L transposase activity
GPNPHLCG_00936 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00937 9.2e-92 batE T Bacterial SH3 domain homologues
GPNPHLCG_00938 6.6e-50 yfhL S SdpI/YhfL protein family
GPNPHLCG_00939 1.3e-170 yfhM S Alpha beta hydrolase
GPNPHLCG_00940 3.6e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNPHLCG_00941 0.0 yfhO S Bacterial membrane protein YfhO
GPNPHLCG_00942 2.1e-185 yfhP S membrane-bound metal-dependent
GPNPHLCG_00943 2.5e-210 mutY L A G-specific
GPNPHLCG_00944 6.9e-36 yfhS
GPNPHLCG_00945 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_00946 5.3e-08 sspE S Small, acid-soluble spore protein, gamma-type
GPNPHLCG_00947 1.5e-37 ygaB S YgaB-like protein
GPNPHLCG_00948 1.3e-104 ygaC J Belongs to the UPF0374 family
GPNPHLCG_00949 1.8e-301 ygaD V ABC transporter
GPNPHLCG_00950 3.6e-178 ygaE S Membrane
GPNPHLCG_00951 4e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPNPHLCG_00952 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
GPNPHLCG_00953 4e-80 perR P Belongs to the Fur family
GPNPHLCG_00954 9.5e-56 ygzB S UPF0295 protein
GPNPHLCG_00955 6.7e-167 ygxA S Nucleotidyltransferase-like
GPNPHLCG_00956 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_00961 7.8e-08
GPNPHLCG_00969 2e-08
GPNPHLCG_00973 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_00974 1.4e-45 L transposase activity
GPNPHLCG_00975 2.5e-141 spo0M S COG4326 Sporulation control protein
GPNPHLCG_00976 1.2e-26
GPNPHLCG_00977 2.3e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
GPNPHLCG_00978 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
GPNPHLCG_00979 7.6e-263 ygaK C Berberine and berberine like
GPNPHLCG_00981 8.7e-289 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPNPHLCG_00982 5.4e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
GPNPHLCG_00983 1.5e-170 ssuA M Sulfonate ABC transporter
GPNPHLCG_00984 4.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNPHLCG_00985 2.6e-216 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
GPNPHLCG_00987 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GPNPHLCG_00988 1.3e-76 ygaO
GPNPHLCG_00989 4.4e-29 K Transcriptional regulator
GPNPHLCG_00991 8.7e-113 yhzB S B3/4 domain
GPNPHLCG_00992 6.6e-223 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GPNPHLCG_00993 2.8e-176 yhbB S Putative amidase domain
GPNPHLCG_00994 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
GPNPHLCG_00995 1.4e-102 yhbD K Protein of unknown function (DUF4004)
GPNPHLCG_00996 2.7e-57 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
GPNPHLCG_00997 0.0 prkA T Ser protein kinase
GPNPHLCG_00998 2.5e-225 yhbH S Belongs to the UPF0229 family
GPNPHLCG_00999 2.2e-76 yhbI K DNA-binding transcription factor activity
GPNPHLCG_01000 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
GPNPHLCG_01001 3.1e-271 yhcA EGP Major facilitator Superfamily
GPNPHLCG_01002 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
GPNPHLCG_01003 2.8e-37 yhcC
GPNPHLCG_01004 2.7e-55
GPNPHLCG_01005 1.9e-59 yhcF K Transcriptional regulator
GPNPHLCG_01006 5.7e-121 yhcG V ABC transporter, ATP-binding protein
GPNPHLCG_01007 5.5e-164 yhcH V ABC transporter, ATP-binding protein
GPNPHLCG_01008 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPNPHLCG_01009 1e-30 cspB K Cold-shock protein
GPNPHLCG_01010 4.4e-152 metQ M Belongs to the nlpA lipoprotein family
GPNPHLCG_01011 2.2e-194 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
GPNPHLCG_01012 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNPHLCG_01013 1.7e-74 L Belongs to the 'phage' integrase family
GPNPHLCG_01014 3.1e-39 immA E Pfam:DUF955
GPNPHLCG_01015 3.6e-29 yvaO K Transcriptional
GPNPHLCG_01016 6.8e-08
GPNPHLCG_01017 6.8e-35
GPNPHLCG_01019 8.6e-63 S Bacterial protein of unknown function (DUF961)
GPNPHLCG_01021 9.5e-253 ydcQ D Ftsk spoiiie family protein
GPNPHLCG_01022 2.7e-199 nicK L Replication initiation factor
GPNPHLCG_01025 1.2e-32 yddA
GPNPHLCG_01026 3.9e-161 yddB S Conjugative transposon protein TcpC
GPNPHLCG_01027 5.7e-39 yddC
GPNPHLCG_01028 1.1e-89 yddD S TcpE family
GPNPHLCG_01029 0.0 yddE S AAA-like domain
GPNPHLCG_01030 7.5e-47 S Domain of unknown function (DUF1874)
GPNPHLCG_01031 0.0 yddG S maturation of SSU-rRNA
GPNPHLCG_01032 2.2e-187 yddH CBM50 M Lysozyme-like
GPNPHLCG_01033 5.3e-84 yddI
GPNPHLCG_01034 2.4e-65 S Domain of unknown function with cystatin-like fold (DUF4467)
GPNPHLCG_01035 1.3e-57 S Domain of unknown function (DUF4145)
GPNPHLCG_01036 2.9e-69 S response regulator aspartate phosphatase
GPNPHLCG_01038 4.9e-41 yhcM
GPNPHLCG_01039 2.1e-61 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNPHLCG_01040 7e-160 yhcP
GPNPHLCG_01041 1.6e-96 yhcQ M Spore coat protein
GPNPHLCG_01042 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
GPNPHLCG_01043 2.1e-103 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
GPNPHLCG_01044 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPNPHLCG_01045 9.3e-68 yhcU S Family of unknown function (DUF5365)
GPNPHLCG_01046 3.8e-67 yhcV S COG0517 FOG CBS domain
GPNPHLCG_01047 1e-119 yhcW 5.4.2.6 S hydrolase
GPNPHLCG_01048 5e-303 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPNPHLCG_01049 5.4e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNPHLCG_01050 3.4e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
GPNPHLCG_01051 1.4e-150 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
GPNPHLCG_01052 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GPNPHLCG_01053 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GPNPHLCG_01054 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
GPNPHLCG_01055 1.4e-212 yhcY 2.7.13.3 T Histidine kinase
GPNPHLCG_01056 6.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_01057 4.2e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
GPNPHLCG_01058 3.6e-38 yhdB S YhdB-like protein
GPNPHLCG_01059 4.8e-54 yhdC S Protein of unknown function (DUF3889)
GPNPHLCG_01060 1e-183 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPNPHLCG_01061 1e-75 nsrR K Transcriptional regulator
GPNPHLCG_01062 2e-88 ygxB M Conserved TM helix
GPNPHLCG_01063 1.4e-143 ygxB M Conserved TM helix
GPNPHLCG_01064 6.8e-262 ycgB S Stage V sporulation protein R
GPNPHLCG_01065 3.5e-255 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
GPNPHLCG_01066 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPNPHLCG_01067 7.1e-161 citR K Transcriptional regulator
GPNPHLCG_01068 5.9e-205 citA 2.3.3.1 C Belongs to the citrate synthase family
GPNPHLCG_01069 5.1e-159 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_01070 7.6e-250 yhdG E amino acid
GPNPHLCG_01071 2.2e-241 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPNPHLCG_01072 2.1e-271 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_01073 5.9e-76 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_01074 8.1e-45 yhdK S Sigma-M inhibitor protein
GPNPHLCG_01075 6.6e-201 yhdL S Sigma factor regulator N-terminal
GPNPHLCG_01076 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_01077 4.4e-191 yhdN C Aldo keto reductase
GPNPHLCG_01078 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GPNPHLCG_01079 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GPNPHLCG_01080 4.1e-74 cueR K transcriptional
GPNPHLCG_01081 3.3e-222 yhdR 2.6.1.1 E Aminotransferase
GPNPHLCG_01082 4.2e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
GPNPHLCG_01083 7.1e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPNPHLCG_01084 1.5e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GPNPHLCG_01085 6.2e-134 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNPHLCG_01087 9.6e-203 yhdY M Mechanosensitive ion channel
GPNPHLCG_01088 8.5e-139 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
GPNPHLCG_01089 6.3e-146 yheN G deacetylase
GPNPHLCG_01090 6.9e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
GPNPHLCG_01091 2.9e-230 nhaC C Na H antiporter
GPNPHLCG_01092 1.7e-83 nhaX T Belongs to the universal stress protein A family
GPNPHLCG_01093 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNPHLCG_01094 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNPHLCG_01095 7.6e-109 yheG GM NAD(P)H-binding
GPNPHLCG_01096 6.3e-28 sspB S spore protein
GPNPHLCG_01097 1.3e-36 yheE S Family of unknown function (DUF5342)
GPNPHLCG_01098 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
GPNPHLCG_01099 4.3e-216 yheC HJ YheC/D like ATP-grasp
GPNPHLCG_01100 6.3e-202 yheB S Belongs to the UPF0754 family
GPNPHLCG_01101 9.5e-48 yheA S Belongs to the UPF0342 family
GPNPHLCG_01102 5.3e-104 yhaZ L DNA alkylation repair enzyme
GPNPHLCG_01103 4.4e-74 yhaZ L DNA alkylation repair enzyme
GPNPHLCG_01104 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
GPNPHLCG_01105 1.8e-292 hemZ H coproporphyrinogen III oxidase
GPNPHLCG_01106 8.2e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
GPNPHLCG_01107 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
GPNPHLCG_01109 6.4e-132 yhaR 5.3.3.18 I enoyl-CoA hydratase
GPNPHLCG_01110 1.1e-26 S YhzD-like protein
GPNPHLCG_01111 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
GPNPHLCG_01112 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
GPNPHLCG_01113 2.6e-225 yhaO L DNA repair exonuclease
GPNPHLCG_01114 0.0 yhaN L AAA domain
GPNPHLCG_01115 5.8e-177 yhaM L Shows a 3'-5' exoribonuclease activity
GPNPHLCG_01116 1.6e-21 yhaL S Sporulation protein YhaL
GPNPHLCG_01117 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
GPNPHLCG_01118 1.1e-89 yhaK S Putative zincin peptidase
GPNPHLCG_01119 1.3e-54 yhaI S Protein of unknown function (DUF1878)
GPNPHLCG_01120 1e-113 hpr K Negative regulator of protease production and sporulation
GPNPHLCG_01121 7e-39 yhaH S YtxH-like protein
GPNPHLCG_01122 3.6e-80 trpP S Tryptophan transporter TrpP
GPNPHLCG_01123 2.9e-204 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GPNPHLCG_01124 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
GPNPHLCG_01125 1.8e-136 ecsA V transporter (ATP-binding protein)
GPNPHLCG_01126 5.4e-215 ecsB U ABC transporter
GPNPHLCG_01127 9e-114 ecsC S EcsC protein family
GPNPHLCG_01128 4.1e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
GPNPHLCG_01129 1.1e-245 yhfA C membrane
GPNPHLCG_01130 1.9e-34 1.15.1.2 C Rubrerythrin
GPNPHLCG_01131 8.4e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
GPNPHLCG_01132 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPNPHLCG_01133 6.3e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GPNPHLCG_01134 3.6e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
GPNPHLCG_01135 4.1e-267 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
GPNPHLCG_01136 4.6e-100 yhgD K Transcriptional regulator
GPNPHLCG_01137 2e-223 yhgE S YhgE Pip N-terminal domain protein
GPNPHLCG_01138 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPNPHLCG_01139 4.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
GPNPHLCG_01140 5.1e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
GPNPHLCG_01141 1.4e-71 3.4.13.21 S ASCH
GPNPHLCG_01142 1.5e-134 L Integrase core domain
GPNPHLCG_01143 6e-44 tnpIS3 L Transposase
GPNPHLCG_01144 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
GPNPHLCG_01145 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
GPNPHLCG_01146 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
GPNPHLCG_01147 1.9e-110 yhfK GM NmrA-like family
GPNPHLCG_01148 7.8e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPNPHLCG_01149 1.9e-65 yhfM
GPNPHLCG_01150 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
GPNPHLCG_01151 4.7e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
GPNPHLCG_01152 4.3e-77 VY92_01935 K acetyltransferase
GPNPHLCG_01153 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
GPNPHLCG_01154 9.3e-154 yfmC M Periplasmic binding protein
GPNPHLCG_01155 1.5e-134 L Integrase core domain
GPNPHLCG_01156 6e-44 tnpIS3 L Transposase
GPNPHLCG_01157 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
GPNPHLCG_01158 3.7e-183 vraB 2.3.1.9 I Belongs to the thiolase family
GPNPHLCG_01159 8.4e-276 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
GPNPHLCG_01160 5e-91 bioY S BioY family
GPNPHLCG_01161 2.8e-182 hemAT NT chemotaxis protein
GPNPHLCG_01162 5.2e-300 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
GPNPHLCG_01163 2.3e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_01164 1.3e-32 yhzC S IDEAL
GPNPHLCG_01165 4.2e-109 comK K Competence transcription factor
GPNPHLCG_01166 3.9e-119 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_01167 3.1e-25 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_01168 2e-26 yhjA S Excalibur calcium-binding domain
GPNPHLCG_01169 6.8e-265 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_01170 6.9e-27 yhjC S Protein of unknown function (DUF3311)
GPNPHLCG_01171 3.3e-59 yhjD
GPNPHLCG_01172 9.1e-110 yhjE S SNARE associated Golgi protein
GPNPHLCG_01173 4.5e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
GPNPHLCG_01174 1.1e-23 yhjG CH FAD binding domain
GPNPHLCG_01175 3.7e-235 yhjG CH FAD binding domain
GPNPHLCG_01176 1.7e-93 yhjH K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_01177 9.9e-214 glcP G Major Facilitator Superfamily
GPNPHLCG_01178 9.3e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
GPNPHLCG_01179 2.6e-160 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
GPNPHLCG_01180 1e-251 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
GPNPHLCG_01181 1.7e-187 yhjM 5.1.1.1 K Transcriptional regulator
GPNPHLCG_01182 1.9e-201 abrB S membrane
GPNPHLCG_01183 3.3e-209 EGP Transmembrane secretion effector
GPNPHLCG_01184 0.0 S Sugar transport-related sRNA regulator N-term
GPNPHLCG_01185 2.2e-78 yhjR S Rubrerythrin
GPNPHLCG_01186 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
GPNPHLCG_01187 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
GPNPHLCG_01188 2.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
GPNPHLCG_01189 0.0 sbcC L COG0419 ATPase involved in DNA repair
GPNPHLCG_01190 7.4e-49 yisB V COG1403 Restriction endonuclease
GPNPHLCG_01191 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
GPNPHLCG_01192 1.2e-62 gerPE S Spore germination protein GerPE
GPNPHLCG_01193 6.3e-24 gerPD S Spore germination protein
GPNPHLCG_01194 5.9e-53 gerPC S Spore germination protein
GPNPHLCG_01195 4e-34 gerPB S cell differentiation
GPNPHLCG_01196 5.4e-33 gerPA S Spore germination protein
GPNPHLCG_01197 1.5e-22 yisI S Spo0E like sporulation regulatory protein
GPNPHLCG_01198 8.5e-173 cotH M Spore Coat
GPNPHLCG_01199 2.1e-171 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
GPNPHLCG_01200 3e-57 yisL S UPF0344 protein
GPNPHLCG_01201 0.0 wprA O Belongs to the peptidase S8 family
GPNPHLCG_01202 1.3e-102 yisN S Protein of unknown function (DUF2777)
GPNPHLCG_01203 0.0 asnO 6.3.5.4 E Asparagine synthase
GPNPHLCG_01204 1.5e-117 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
GPNPHLCG_01205 2e-242 yisQ V Mate efflux family protein
GPNPHLCG_01206 3.5e-160 yisR K Transcriptional regulator
GPNPHLCG_01207 7.1e-181 purR K helix_turn _helix lactose operon repressor
GPNPHLCG_01208 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
GPNPHLCG_01209 7.8e-91 yisT S DinB family
GPNPHLCG_01210 1.2e-106 argO S Lysine exporter protein LysE YggA
GPNPHLCG_01211 7.6e-277 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_01212 2e-35 mcbG S Pentapeptide repeats (9 copies)
GPNPHLCG_01213 4.2e-152 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GPNPHLCG_01214 6e-111 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
GPNPHLCG_01215 5.1e-164 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GPNPHLCG_01216 5.4e-52 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GPNPHLCG_01217 1.5e-57 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GPNPHLCG_01218 5e-64 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GPNPHLCG_01219 1.6e-123 comB 3.1.3.71 H Belongs to the ComB family
GPNPHLCG_01220 1.9e-141 yitD 4.4.1.19 S synthase
GPNPHLCG_01221 4.2e-107 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPNPHLCG_01222 4.7e-87 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNPHLCG_01223 5.6e-46 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNPHLCG_01224 1.8e-50 L Transposase and inactivated derivatives, TnpA family
GPNPHLCG_01225 1.8e-20 L Transposase and inactivated derivatives, TnpA family
GPNPHLCG_01226 1.7e-76
GPNPHLCG_01227 1.1e-98 EG Spore germination protein
GPNPHLCG_01228 5.3e-67 S TIGRFAM germination protein, Ger(x)C family
GPNPHLCG_01229 1.5e-24 S Protein of unknown function (DUF2642)
GPNPHLCG_01230 9.4e-161 cat P Catalase
GPNPHLCG_01231 6e-26 S Protein of unknown function (DUF1657)
GPNPHLCG_01232 4.1e-78 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNPHLCG_01233 2.6e-80 spoVAC S stage V sporulation protein AC
GPNPHLCG_01234 1e-195 spoVAD I Stage V sporulation protein AD
GPNPHLCG_01235 2.5e-56 spoVAE S stage V sporulation protein
GPNPHLCG_01236 5.8e-29 S Protein of unknown function (DUF1657)
GPNPHLCG_01237 2.5e-150 yetF1 S membrane
GPNPHLCG_01238 2.8e-07 S Protein of unknown function (DUF421)
GPNPHLCG_01239 1.2e-70 S Protein of unknown function (DUF421)
GPNPHLCG_01240 5.4e-286 clsA_1 I PLD-like domain
GPNPHLCG_01241 2.5e-74 S Protein of unknown function (DUF421)
GPNPHLCG_01242 1.5e-228 yitG EGP Major facilitator Superfamily
GPNPHLCG_01243 1.5e-155 yitH K Acetyltransferase (GNAT) domain
GPNPHLCG_01244 3e-70 yjcF S Acetyltransferase (GNAT) domain
GPNPHLCG_01245 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
GPNPHLCG_01246 3.3e-54 yajQ S Belongs to the UPF0234 family
GPNPHLCG_01247 4.5e-160 cvfB S protein conserved in bacteria
GPNPHLCG_01249 9e-36 yitR S Domain of unknown function (DUF3784)
GPNPHLCG_01250 1.4e-45 L transposase activity
GPNPHLCG_01251 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_01252 3.5e-157 yitS S protein conserved in bacteria
GPNPHLCG_01253 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
GPNPHLCG_01254 5e-73 ipi S Intracellular proteinase inhibitor
GPNPHLCG_01255 1.2e-17 S Protein of unknown function (DUF3813)
GPNPHLCG_01257 6e-154 yitU 3.1.3.104 S hydrolases of the HAD superfamily
GPNPHLCG_01258 2.9e-142 yjfP S COG1073 Hydrolases of the alpha beta superfamily
GPNPHLCG_01259 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
GPNPHLCG_01260 1.5e-22 pilT S Proteolipid membrane potential modulator
GPNPHLCG_01261 2.9e-268 yitY C D-arabinono-1,4-lactone oxidase
GPNPHLCG_01262 1.7e-88 norB G Major Facilitator Superfamily
GPNPHLCG_01263 3.6e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GPNPHLCG_01264 2.9e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GPNPHLCG_01265 4.1e-136 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
GPNPHLCG_01266 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
GPNPHLCG_01267 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPNPHLCG_01268 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
GPNPHLCG_01269 1.5e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GPNPHLCG_01270 9.5e-28 yjzC S YjzC-like protein
GPNPHLCG_01271 2.3e-16 yjzD S Protein of unknown function (DUF2929)
GPNPHLCG_01272 6.8e-141 yjaU I carboxylic ester hydrolase activity
GPNPHLCG_01273 6.4e-99 yjaV
GPNPHLCG_01274 2.5e-183 med S Transcriptional activator protein med
GPNPHLCG_01275 7.3e-26 comZ S ComZ
GPNPHLCG_01276 2.7e-22 yjzB
GPNPHLCG_01277 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GPNPHLCG_01278 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
GPNPHLCG_01279 1.4e-147 yjaZ O Zn-dependent protease
GPNPHLCG_01280 1.8e-184 appD P Belongs to the ABC transporter superfamily
GPNPHLCG_01281 3.6e-185 appF E Belongs to the ABC transporter superfamily
GPNPHLCG_01282 3.1e-250 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
GPNPHLCG_01283 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01284 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01285 5e-147 yjbA S Belongs to the UPF0736 family
GPNPHLCG_01286 3e-184 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
GPNPHLCG_01287 0.0 oppA E ABC transporter substrate-binding protein
GPNPHLCG_01288 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01289 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01290 3.4e-197 oppD P Belongs to the ABC transporter superfamily
GPNPHLCG_01291 5.5e-172 oppF E Belongs to the ABC transporter superfamily
GPNPHLCG_01292 7.7e-203 yjbB EGP Major Facilitator Superfamily
GPNPHLCG_01293 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_01294 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
GPNPHLCG_01295 6e-112 yjbE P Integral membrane protein TerC family
GPNPHLCG_01296 4.4e-115 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPNPHLCG_01297 4e-220 yjbF S Competence protein
GPNPHLCG_01298 0.0 pepF E oligoendopeptidase F
GPNPHLCG_01299 1.8e-20
GPNPHLCG_01301 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GPNPHLCG_01302 3.7e-72 yjbI S Bacterial-like globin
GPNPHLCG_01303 6e-97 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPNPHLCG_01304 4.1e-101 yjbK S protein conserved in bacteria
GPNPHLCG_01305 7.1e-62 yjbL S Belongs to the UPF0738 family
GPNPHLCG_01306 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
GPNPHLCG_01307 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPNPHLCG_01308 5.2e-159 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPNPHLCG_01309 1.5e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
GPNPHLCG_01310 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
GPNPHLCG_01311 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GPNPHLCG_01312 3e-105 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
GPNPHLCG_01313 2.6e-216 thiO 1.4.3.19 E Glycine oxidase
GPNPHLCG_01314 6.7e-30 thiS H thiamine diphosphate biosynthetic process
GPNPHLCG_01315 2.6e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
GPNPHLCG_01316 6.7e-187 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GPNPHLCG_01317 1.3e-148 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPNPHLCG_01318 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
GPNPHLCG_01319 1.4e-52 yjbX S Spore coat protein
GPNPHLCG_01320 5.2e-83 cotZ S Spore coat protein
GPNPHLCG_01321 3.4e-96 cotY S Spore coat protein Z
GPNPHLCG_01322 6.4e-77 cotX S Spore Coat Protein X and V domain
GPNPHLCG_01323 5.5e-31 cotW
GPNPHLCG_01324 2.3e-55 cotV S Spore Coat Protein X and V domain
GPNPHLCG_01325 4.3e-56 yjcA S Protein of unknown function (DUF1360)
GPNPHLCG_01328 2.9e-38 spoVIF S Stage VI sporulation protein F
GPNPHLCG_01329 0.0 yjcD 3.6.4.12 L DNA helicase
GPNPHLCG_01330 1.7e-38
GPNPHLCG_01331 6.6e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_01332 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
GPNPHLCG_01333 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
GPNPHLCG_01334 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPNPHLCG_01335 2.5e-217 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPNPHLCG_01336 5.3e-98 rimJ 2.3.1.128 J Alanine acetyltransferase
GPNPHLCG_01337 1.3e-210 yjcL S Protein of unknown function (DUF819)
GPNPHLCG_01340 1.3e-37
GPNPHLCG_01341 1e-29
GPNPHLCG_01342 5e-238 M nucleic acid phosphodiester bond hydrolysis
GPNPHLCG_01344 1.4e-45 L transposase activity
GPNPHLCG_01345 2.1e-143 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_01346 2.4e-29 KLT Protein tyrosine kinase
GPNPHLCG_01347 4.3e-11 S YolD-like protein
GPNPHLCG_01348 1.9e-36
GPNPHLCG_01349 9e-19
GPNPHLCG_01350 5.1e-18
GPNPHLCG_01351 1.1e-46 yjcS S Antibiotic biosynthesis monooxygenase
GPNPHLCG_01352 2.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_01354 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
GPNPHLCG_01355 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
GPNPHLCG_01356 5.5e-183 manA 5.3.1.8 G mannose-6-phosphate isomerase
GPNPHLCG_01357 2.4e-50 yjdF S Protein of unknown function (DUF2992)
GPNPHLCG_01358 1.3e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
GPNPHLCG_01360 5.2e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GPNPHLCG_01361 4.2e-29 S Domain of unknown function (DUF4177)
GPNPHLCG_01362 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
GPNPHLCG_01363 5.6e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GPNPHLCG_01365 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
GPNPHLCG_01366 4.9e-201 L COG3666 Transposase and inactivated derivatives
GPNPHLCG_01367 1.8e-81 S Protein of unknown function (DUF2690)
GPNPHLCG_01368 2.3e-20 yjfB S Putative motility protein
GPNPHLCG_01369 3.3e-169 yjfC O Predicted Zn-dependent protease (DUF2268)
GPNPHLCG_01370 3.9e-44 T PhoQ Sensor
GPNPHLCG_01371 2.9e-102 yjgB S Domain of unknown function (DUF4309)
GPNPHLCG_01372 1.7e-262 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
GPNPHLCG_01373 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
GPNPHLCG_01374 4.3e-95 yjgD S Protein of unknown function (DUF1641)
GPNPHLCG_01375 8.7e-07 S Domain of unknown function (DUF4352)
GPNPHLCG_01376 3.9e-68 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
GPNPHLCG_01378 6.4e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
GPNPHLCG_01379 4.2e-217 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
GPNPHLCG_01380 8.2e-30
GPNPHLCG_01381 1.9e-144 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPNPHLCG_01382 2.8e-121 ybbM S transport system, permease component
GPNPHLCG_01383 2e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
GPNPHLCG_01384 6.7e-176 yjlA EG Putative multidrug resistance efflux transporter
GPNPHLCG_01385 1.1e-89 yjlB S Cupin domain
GPNPHLCG_01386 7.1e-66 yjlC S Protein of unknown function (DUF1641)
GPNPHLCG_01387 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
GPNPHLCG_01388 1e-278 uxaC 5.3.1.12 G glucuronate isomerase
GPNPHLCG_01389 3.5e-247 yjmB G symporter YjmB
GPNPHLCG_01390 1.4e-189 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
GPNPHLCG_01391 2.8e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
GPNPHLCG_01392 6e-210 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
GPNPHLCG_01393 3.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_01394 1.1e-226 exuT G Sugar (and other) transporter
GPNPHLCG_01395 2e-183 exuR K transcriptional
GPNPHLCG_01396 7.1e-283 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
GPNPHLCG_01397 3.2e-286 uxaA 4.2.1.7, 4.4.1.24 G Altronate
GPNPHLCG_01398 1.3e-129 MA20_18170 S membrane transporter protein
GPNPHLCG_01399 2.3e-78 yjoA S DinB family
GPNPHLCG_01400 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
GPNPHLCG_01401 2.1e-213 S response regulator aspartate phosphatase
GPNPHLCG_01403 1.2e-39 S YCII-related domain
GPNPHLCG_01404 1.6e-158 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
GPNPHLCG_01405 1.8e-60 yjqA S Bacterial PH domain
GPNPHLCG_01406 4.2e-112 yjqB S Pfam:DUF867
GPNPHLCG_01407 4.4e-160 ydbD P Catalase
GPNPHLCG_01408 1.6e-111 xkdA E IrrE N-terminal-like domain
GPNPHLCG_01409 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
GPNPHLCG_01411 5.9e-157 xkdB K sequence-specific DNA binding
GPNPHLCG_01412 6.4e-119 xkdC L Bacterial dnaA protein
GPNPHLCG_01415 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
GPNPHLCG_01416 7.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GPNPHLCG_01417 1.4e-139 xtmA L phage terminase small subunit
GPNPHLCG_01418 6.9e-253 xtmB S phage terminase, large subunit
GPNPHLCG_01419 1.6e-285 yqbA S portal protein
GPNPHLCG_01420 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
GPNPHLCG_01421 5.8e-169 xkdG S Phage capsid family
GPNPHLCG_01422 5.6e-62 yqbG S Protein of unknown function (DUF3199)
GPNPHLCG_01423 8.7e-65 yqbH S Domain of unknown function (DUF3599)
GPNPHLCG_01424 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
GPNPHLCG_01425 9.3e-77 xkdJ
GPNPHLCG_01426 2.5e-256 xkdK S Phage tail sheath C-terminal domain
GPNPHLCG_01427 6.1e-76 xkdM S Phage tail tube protein
GPNPHLCG_01428 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
GPNPHLCG_01429 2.1e-265 xkdO L Transglycosylase SLT domain
GPNPHLCG_01430 3.7e-122 xkdP S Lysin motif
GPNPHLCG_01431 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
GPNPHLCG_01432 2.1e-39 xkdR S Protein of unknown function (DUF2577)
GPNPHLCG_01433 6.3e-70 xkdS S Protein of unknown function (DUF2634)
GPNPHLCG_01434 5.6e-189 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
GPNPHLCG_01435 9e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
GPNPHLCG_01436 6.7e-41
GPNPHLCG_01437 5.5e-179
GPNPHLCG_01438 3.1e-45 xkdW S XkdW protein
GPNPHLCG_01439 5.5e-22 xkdX
GPNPHLCG_01440 2e-152 xepA
GPNPHLCG_01441 6.2e-39 xhlA S Haemolysin XhlA
GPNPHLCG_01442 2.7e-39 xhlB S SPP1 phage holin
GPNPHLCG_01443 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNPHLCG_01444 6.7e-23 spoIISB S Stage II sporulation protein SB
GPNPHLCG_01445 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
GPNPHLCG_01446 5.8e-175 pit P phosphate transporter
GPNPHLCG_01447 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
GPNPHLCG_01448 6.1e-241 steT E amino acid
GPNPHLCG_01449 1.8e-181 mhqA E COG0346 Lactoylglutathione lyase and related lyases
GPNPHLCG_01450 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPNPHLCG_01451 8.4e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNPHLCG_01453 3.2e-213 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNPHLCG_01454 2.6e-133 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
GPNPHLCG_01455 5.1e-153 dppA E D-aminopeptidase
GPNPHLCG_01456 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01457 4.8e-174 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
GPNPHLCG_01458 2.6e-183 dppD P Belongs to the ABC transporter superfamily
GPNPHLCG_01459 0.0 dppE E ABC transporter substrate-binding protein
GPNPHLCG_01461 1.6e-174 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
GPNPHLCG_01462 8.3e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
GPNPHLCG_01463 4.4e-166 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GPNPHLCG_01464 7.2e-186 ykfD E Belongs to the ABC transporter superfamily
GPNPHLCG_01465 1.4e-203 pgl 3.1.1.31 G 6-phosphogluconolactonase
GPNPHLCG_01466 6.1e-157 ykgA E Amidinotransferase
GPNPHLCG_01467 3.4e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
GPNPHLCG_01468 1.2e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GPNPHLCG_01469 1.5e-09
GPNPHLCG_01470 8.6e-128 ykjA S Protein of unknown function (DUF421)
GPNPHLCG_01471 2.2e-96 ykkA S Protein of unknown function (DUF664)
GPNPHLCG_01472 9.5e-97 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPNPHLCG_01473 2.9e-54 ykkC P Multidrug resistance protein
GPNPHLCG_01474 9.1e-50 ykkD P Multidrug resistance protein
GPNPHLCG_01475 6.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
GPNPHLCG_01476 5.2e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPNPHLCG_01477 2.4e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GPNPHLCG_01478 1.3e-70 ohrA O Organic hydroperoxide resistance protein
GPNPHLCG_01479 4.8e-73 ohrR K COG1846 Transcriptional regulators
GPNPHLCG_01480 2.4e-71 ohrB O Organic hydroperoxide resistance protein
GPNPHLCG_01481 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
GPNPHLCG_01482 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GPNPHLCG_01483 5e-176 isp O Belongs to the peptidase S8 family
GPNPHLCG_01484 3.1e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPNPHLCG_01485 5.3e-136 ykoC P Cobalt transport protein
GPNPHLCG_01486 6.3e-304 P ABC transporter, ATP-binding protein
GPNPHLCG_01487 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
GPNPHLCG_01488 5.1e-110 ykoF S YKOF-related Family
GPNPHLCG_01489 1.8e-122 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_01490 5.7e-159 ykoH 2.7.13.3 T Histidine kinase
GPNPHLCG_01491 3e-67 ykoH 2.7.13.3 T Histidine kinase
GPNPHLCG_01492 3.1e-69 ykoI S Peptidase propeptide and YPEB domain
GPNPHLCG_01493 9.2e-84 ykoJ S Peptidase propeptide and YPEB domain
GPNPHLCG_01496 2.2e-222 mgtE P Acts as a magnesium transporter
GPNPHLCG_01497 1.4e-53 tnrA K transcriptional
GPNPHLCG_01498 5.9e-18
GPNPHLCG_01499 3.4e-25 ykoL
GPNPHLCG_01500 1.3e-81 mhqR K transcriptional
GPNPHLCG_01501 1.6e-218 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
GPNPHLCG_01502 1.1e-98 ykoP G polysaccharide deacetylase
GPNPHLCG_01503 1e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
GPNPHLCG_01504 0.0 ykoS
GPNPHLCG_01505 3.1e-184 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNPHLCG_01506 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
GPNPHLCG_01507 1.5e-158 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GPNPHLCG_01508 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
GPNPHLCG_01509 3.5e-109 ykoX S membrane-associated protein
GPNPHLCG_01510 4.6e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
GPNPHLCG_01511 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_01512 5e-114 rsgI S Anti-sigma factor N-terminus
GPNPHLCG_01513 1.9e-26 sspD S small acid-soluble spore protein
GPNPHLCG_01514 1.9e-124 ykrK S Domain of unknown function (DUF1836)
GPNPHLCG_01515 3.9e-154 htpX O Belongs to the peptidase M48B family
GPNPHLCG_01516 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
GPNPHLCG_01517 1.2e-10 ydfR S Protein of unknown function (DUF421)
GPNPHLCG_01518 2.2e-21 ykzE
GPNPHLCG_01519 1.1e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
GPNPHLCG_01520 0.0 kinE 2.7.13.3 T Histidine kinase
GPNPHLCG_01521 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GPNPHLCG_01523 8.2e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
GPNPHLCG_01524 8.3e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
GPNPHLCG_01525 5e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
GPNPHLCG_01526 3.4e-230 mtnE 2.6.1.83 E Aminotransferase
GPNPHLCG_01527 2.2e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
GPNPHLCG_01528 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
GPNPHLCG_01529 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
GPNPHLCG_01530 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
GPNPHLCG_01531 5.4e-50 XK27_09985 S Protein of unknown function (DUF1232)
GPNPHLCG_01532 6.4e-09 S Spo0E like sporulation regulatory protein
GPNPHLCG_01533 3.1e-51 eag
GPNPHLCG_01534 2.4e-273 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPNPHLCG_01535 1.3e-75 ykvE K transcriptional
GPNPHLCG_01536 2e-122 motB N Flagellar motor protein
GPNPHLCG_01537 5.1e-137 motA N flagellar motor
GPNPHLCG_01538 0.0 clpE O Belongs to the ClpA ClpB family
GPNPHLCG_01539 4e-179 ykvI S membrane
GPNPHLCG_01540 2.3e-124 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GPNPHLCG_01541 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
GPNPHLCG_01542 6.4e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
GPNPHLCG_01543 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPNPHLCG_01544 7.6e-61 ykvN K HxlR-like helix-turn-helix
GPNPHLCG_01545 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_01546 7.7e-27 K Cro/C1-type HTH DNA-binding domain
GPNPHLCG_01547 1.3e-45
GPNPHLCG_01548 9e-254 I Pfam Lipase (class 3)
GPNPHLCG_01549 2.7e-41 S Protein of unknown function (DUF1433)
GPNPHLCG_01550 3.9e-27 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
GPNPHLCG_01551 2.2e-11
GPNPHLCG_01553 1.8e-83 2.7.7.49 L reverse transcriptase
GPNPHLCG_01554 3.7e-76 G Glycosyl hydrolases family 18
GPNPHLCG_01555 1.1e-44 ykvR S Protein of unknown function (DUF3219)
GPNPHLCG_01556 6e-25 ykvS S protein conserved in bacteria
GPNPHLCG_01557 2.8e-28
GPNPHLCG_01558 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
GPNPHLCG_01559 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_01560 9.2e-89 stoA CO thiol-disulfide
GPNPHLCG_01561 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPNPHLCG_01562 8.2e-207 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPNPHLCG_01563 5.4e-178 ykvZ 5.1.1.1 K Transcriptional regulator
GPNPHLCG_01564 2.2e-127 glcT K antiterminator
GPNPHLCG_01565 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_01566 2.1e-39 ptsH G phosphocarrier protein HPr
GPNPHLCG_01567 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GPNPHLCG_01568 7.2e-39 splA S Transcriptional regulator
GPNPHLCG_01569 7.5e-202 splB 4.1.99.14 L Spore photoproduct lyase
GPNPHLCG_01570 3.9e-125 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_01571 3.3e-259 mcpC NT chemotaxis protein
GPNPHLCG_01572 1.5e-158 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
GPNPHLCG_01573 8e-124 ykwD J protein with SCP PR1 domains
GPNPHLCG_01574 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
GPNPHLCG_01575 0.0 pilS 2.7.13.3 T Histidine kinase
GPNPHLCG_01576 4.4e-222 patA 2.6.1.1 E Aminotransferase
GPNPHLCG_01577 2.2e-15
GPNPHLCG_01578 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
GPNPHLCG_01579 1.7e-84 ykyB S YkyB-like protein
GPNPHLCG_01580 4.8e-238 ykuC EGP Major facilitator Superfamily
GPNPHLCG_01581 1.5e-86 ykuD S protein conserved in bacteria
GPNPHLCG_01582 1.6e-165 ykuE S Metallophosphoesterase
GPNPHLCG_01583 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_01584 3.3e-233 ykuI T Diguanylate phosphodiesterase
GPNPHLCG_01586 3.9e-37 ykuJ S protein conserved in bacteria
GPNPHLCG_01587 4.4e-94 ykuK S Ribonuclease H-like
GPNPHLCG_01588 3.9e-27 ykzF S Antirepressor AbbA
GPNPHLCG_01589 7.9e-76 ykuL S CBS domain
GPNPHLCG_01590 3.5e-168 ccpC K Transcriptional regulator
GPNPHLCG_01591 1.7e-84 fld C Flavodoxin domain
GPNPHLCG_01592 2.6e-174 ykuO
GPNPHLCG_01593 1.6e-76 fld C Flavodoxin
GPNPHLCG_01594 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
GPNPHLCG_01595 1.6e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
GPNPHLCG_01596 9e-37 ykuS S Belongs to the UPF0180 family
GPNPHLCG_01597 2.6e-141 ykuT M Mechanosensitive ion channel
GPNPHLCG_01598 3.9e-101 ykuU O Alkyl hydroperoxide reductase
GPNPHLCG_01599 5.4e-80 ykuV CO thiol-disulfide
GPNPHLCG_01600 5.8e-95 rok K Repressor of ComK
GPNPHLCG_01601 1.2e-145 yknT
GPNPHLCG_01602 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
GPNPHLCG_01603 1.3e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
GPNPHLCG_01604 9.3e-242 moeA 2.10.1.1 H molybdopterin
GPNPHLCG_01605 3.8e-93 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
GPNPHLCG_01606 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
GPNPHLCG_01607 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GPNPHLCG_01608 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNPHLCG_01609 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
GPNPHLCG_01610 1e-117 yknW S Yip1 domain
GPNPHLCG_01611 4.3e-158 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GPNPHLCG_01612 7.2e-124 macB V ABC transporter, ATP-binding protein
GPNPHLCG_01613 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
GPNPHLCG_01614 3.1e-136 fruR K Transcriptional regulator
GPNPHLCG_01615 1.5e-166 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
GPNPHLCG_01616 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
GPNPHLCG_01617 2.4e-104 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPNPHLCG_01618 1.1e-38 ykoA
GPNPHLCG_01619 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
GPNPHLCG_01620 2e-166 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPNPHLCG_01621 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
GPNPHLCG_01622 1.1e-12 S Uncharacterized protein YkpC
GPNPHLCG_01623 7.7e-183 mreB D Rod-share determining protein MreBH
GPNPHLCG_01624 1.5e-43 abrB K of stationary sporulation gene expression
GPNPHLCG_01625 3.3e-239 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPNPHLCG_01626 2.5e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
GPNPHLCG_01627 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
GPNPHLCG_01628 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GPNPHLCG_01629 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPNPHLCG_01630 8.2e-31 ykzG S Belongs to the UPF0356 family
GPNPHLCG_01631 5.5e-147 ykrA S hydrolases of the HAD superfamily
GPNPHLCG_01632 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPNPHLCG_01634 1.7e-114 recN L Putative cell-wall binding lipoprotein
GPNPHLCG_01635 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNPHLCG_01636 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNPHLCG_01637 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNPHLCG_01638 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPNPHLCG_01639 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
GPNPHLCG_01640 1e-276 speA 4.1.1.19 E Arginine
GPNPHLCG_01641 5.9e-42 yktA S Belongs to the UPF0223 family
GPNPHLCG_01642 2.1e-117 yktB S Belongs to the UPF0637 family
GPNPHLCG_01643 7.1e-26 ykzI
GPNPHLCG_01644 9.7e-149 suhB 3.1.3.25 G Inositol monophosphatase
GPNPHLCG_01645 6.9e-78 ykzC S Acetyltransferase (GNAT) family
GPNPHLCG_01646 1.9e-169 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GPNPHLCG_01647 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
GPNPHLCG_01648 0.0 ylaA
GPNPHLCG_01649 6.6e-41 ylaB
GPNPHLCG_01650 1.1e-87 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_01651 2e-11 sigC S Putative zinc-finger
GPNPHLCG_01652 2.6e-37 ylaE
GPNPHLCG_01653 8.2e-22 S Family of unknown function (DUF5325)
GPNPHLCG_01654 0.0 typA T GTP-binding protein TypA
GPNPHLCG_01655 4.2e-47 ylaH S YlaH-like protein
GPNPHLCG_01656 2.5e-32 ylaI S protein conserved in bacteria
GPNPHLCG_01657 3.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNPHLCG_01658 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
GPNPHLCG_01659 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GPNPHLCG_01660 6.2e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
GPNPHLCG_01661 8.7e-44 ylaN S Belongs to the UPF0358 family
GPNPHLCG_01662 1.2e-211 ftsW D Belongs to the SEDS family
GPNPHLCG_01663 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GPNPHLCG_01664 8.5e-165 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
GPNPHLCG_01665 7.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
GPNPHLCG_01666 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
GPNPHLCG_01667 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPNPHLCG_01668 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
GPNPHLCG_01669 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
GPNPHLCG_01670 3e-167 ctaG S cytochrome c oxidase
GPNPHLCG_01671 7e-62 ylbA S YugN-like family
GPNPHLCG_01672 4.4e-74 ylbB T COG0517 FOG CBS domain
GPNPHLCG_01673 4.3e-200 ylbC S protein with SCP PR1 domains
GPNPHLCG_01674 4.1e-63 ylbD S Putative coat protein
GPNPHLCG_01675 6.7e-37 ylbE S YlbE-like protein
GPNPHLCG_01676 1.8e-75 ylbF S Belongs to the UPF0342 family
GPNPHLCG_01677 3.7e-38 ylbG S UPF0298 protein
GPNPHLCG_01678 7.3e-95 rsmD 2.1.1.171 L Methyltransferase
GPNPHLCG_01679 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GPNPHLCG_01680 2.5e-220 ylbJ S Sporulation integral membrane protein YlbJ
GPNPHLCG_01681 6.4e-137 ylbK S esterase of the alpha-beta hydrolase superfamily
GPNPHLCG_01682 2.6e-186 ylbL T Belongs to the peptidase S16 family
GPNPHLCG_01683 2.8e-235 ylbM S Belongs to the UPF0348 family
GPNPHLCG_01685 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
GPNPHLCG_01686 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
GPNPHLCG_01687 8.3e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
GPNPHLCG_01688 1.5e-88 ylbP K n-acetyltransferase
GPNPHLCG_01689 1.6e-168 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GPNPHLCG_01690 1.2e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GPNPHLCG_01691 2.9e-78 mraZ K Belongs to the MraZ family
GPNPHLCG_01692 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
GPNPHLCG_01693 3.7e-44 ftsL D Essential cell division protein
GPNPHLCG_01694 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
GPNPHLCG_01695 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
GPNPHLCG_01696 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GPNPHLCG_01697 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GPNPHLCG_01698 7.7e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GPNPHLCG_01699 5.7e-186 spoVE D Belongs to the SEDS family
GPNPHLCG_01700 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GPNPHLCG_01701 5.3e-167 murB 1.3.1.98 M cell wall formation
GPNPHLCG_01702 2.2e-137 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
GPNPHLCG_01703 2.4e-103 ylxW S protein conserved in bacteria
GPNPHLCG_01704 1e-102 ylxX S protein conserved in bacteria
GPNPHLCG_01705 6.2e-58 sbp S small basic protein
GPNPHLCG_01706 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
GPNPHLCG_01707 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GPNPHLCG_01708 0.0 bpr O COG1404 Subtilisin-like serine proteases
GPNPHLCG_01709 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
GPNPHLCG_01710 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_01711 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_01712 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
GPNPHLCG_01713 2.6e-252 argE 3.5.1.16 E Acetylornithine deacetylase
GPNPHLCG_01714 2.4e-37 ylmC S sporulation protein
GPNPHLCG_01715 7.8e-157 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
GPNPHLCG_01716 2.1e-123 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GPNPHLCG_01717 5.1e-62 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
GPNPHLCG_01718 1.3e-39 yggT S membrane
GPNPHLCG_01719 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
GPNPHLCG_01720 2.6e-67 divIVA D Cell division initiation protein
GPNPHLCG_01721 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GPNPHLCG_01722 2.5e-62 dksA T COG1734 DnaK suppressor protein
GPNPHLCG_01723 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GPNPHLCG_01724 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
GPNPHLCG_01725 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GPNPHLCG_01726 1.5e-231 pyrP F Xanthine uracil
GPNPHLCG_01727 2.6e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
GPNPHLCG_01728 3.5e-249 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
GPNPHLCG_01729 1.4e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
GPNPHLCG_01730 0.0 carB 6.3.5.5 F Belongs to the CarB family
GPNPHLCG_01731 3.4e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
GPNPHLCG_01732 2.7e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
GPNPHLCG_01733 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
GPNPHLCG_01734 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GPNPHLCG_01736 2.2e-141 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
GPNPHLCG_01737 4.1e-179 cysP P phosphate transporter
GPNPHLCG_01738 3.3e-222 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
GPNPHLCG_01739 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
GPNPHLCG_01740 2.4e-144 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
GPNPHLCG_01741 4.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
GPNPHLCG_01742 4.8e-82 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
GPNPHLCG_01743 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
GPNPHLCG_01744 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
GPNPHLCG_01745 2.4e-156 yloC S stress-induced protein
GPNPHLCG_01746 1.5e-40 ylzA S Belongs to the UPF0296 family
GPNPHLCG_01747 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
GPNPHLCG_01748 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
GPNPHLCG_01749 7e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GPNPHLCG_01750 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GPNPHLCG_01751 1.3e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
GPNPHLCG_01752 8.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GPNPHLCG_01753 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GPNPHLCG_01754 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
GPNPHLCG_01755 2.3e-139 stp 3.1.3.16 T phosphatase
GPNPHLCG_01756 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
GPNPHLCG_01757 4.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
GPNPHLCG_01758 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
GPNPHLCG_01759 6.9e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
GPNPHLCG_01760 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
GPNPHLCG_01761 5.5e-59 asp S protein conserved in bacteria
GPNPHLCG_01762 1.8e-298 yloV S kinase related to dihydroxyacetone kinase
GPNPHLCG_01763 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
GPNPHLCG_01764 4.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
GPNPHLCG_01765 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GPNPHLCG_01766 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
GPNPHLCG_01767 8.1e-177 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
GPNPHLCG_01768 2.9e-168 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
GPNPHLCG_01769 6.1e-129 IQ reductase
GPNPHLCG_01770 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
GPNPHLCG_01771 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
GPNPHLCG_01772 0.0 smc D Required for chromosome condensation and partitioning
GPNPHLCG_01773 1.3e-174 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
GPNPHLCG_01774 6.1e-124 S Phosphotransferase enzyme family
GPNPHLCG_01775 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
GPNPHLCG_01776 3e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GPNPHLCG_01777 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
GPNPHLCG_01778 4.5e-36 ylqC S Belongs to the UPF0109 family
GPNPHLCG_01779 1.4e-60 ylqD S YlqD protein
GPNPHLCG_01780 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GPNPHLCG_01781 3.5e-137 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
GPNPHLCG_01782 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
GPNPHLCG_01783 2.1e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
GPNPHLCG_01784 1e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPNPHLCG_01785 2.7e-289 ylqG
GPNPHLCG_01786 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
GPNPHLCG_01787 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
GPNPHLCG_01788 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GPNPHLCG_01789 8e-168 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
GPNPHLCG_01790 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GPNPHLCG_01791 1.4e-245 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
GPNPHLCG_01792 2.5e-169 xerC L tyrosine recombinase XerC
GPNPHLCG_01793 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
GPNPHLCG_01794 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
GPNPHLCG_01795 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
GPNPHLCG_01796 3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
GPNPHLCG_01797 7.6e-74 flgC N Belongs to the flagella basal body rod proteins family
GPNPHLCG_01798 1.9e-31 fliE N Flagellar hook-basal body
GPNPHLCG_01799 9.1e-255 fliF N The M ring may be actively involved in energy transduction
GPNPHLCG_01800 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNPHLCG_01801 1.7e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
GPNPHLCG_01802 3.6e-241 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
GPNPHLCG_01803 1.5e-69 fliJ N Flagellar biosynthesis chaperone
GPNPHLCG_01804 1.1e-35 ylxF S MgtE intracellular N domain
GPNPHLCG_01805 1.4e-214 fliK N Flagellar hook-length control protein
GPNPHLCG_01806 2.3e-72 flgD N Flagellar basal body rod modification protein
GPNPHLCG_01807 1.9e-136 flgG N Flagellar basal body rod
GPNPHLCG_01808 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
GPNPHLCG_01809 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNPHLCG_01810 1.7e-183 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
GPNPHLCG_01811 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
GPNPHLCG_01812 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
GPNPHLCG_01813 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
GPNPHLCG_01814 2.2e-36 fliQ N Role in flagellar biosynthesis
GPNPHLCG_01815 1.1e-131 fliR N Flagellar biosynthetic protein FliR
GPNPHLCG_01816 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPNPHLCG_01817 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
GPNPHLCG_01818 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
GPNPHLCG_01819 4.1e-156 flhG D Belongs to the ParA family
GPNPHLCG_01820 7.5e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
GPNPHLCG_01821 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
GPNPHLCG_01822 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
GPNPHLCG_01823 7e-110 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
GPNPHLCG_01824 4.3e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
GPNPHLCG_01825 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_01826 3.1e-76 ylxL
GPNPHLCG_01827 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
GPNPHLCG_01828 8.2e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GPNPHLCG_01829 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
GPNPHLCG_01830 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
GPNPHLCG_01831 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GPNPHLCG_01832 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
GPNPHLCG_01833 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
GPNPHLCG_01834 7.7e-233 rasP M zinc metalloprotease
GPNPHLCG_01835 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
GPNPHLCG_01836 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GPNPHLCG_01837 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
GPNPHLCG_01838 1.1e-203 nusA K Participates in both transcription termination and antitermination
GPNPHLCG_01839 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
GPNPHLCG_01840 3.1e-47 ylxQ J ribosomal protein
GPNPHLCG_01841 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GPNPHLCG_01842 3.9e-44 ylxP S protein conserved in bacteria
GPNPHLCG_01843 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GPNPHLCG_01844 4.3e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GPNPHLCG_01845 2e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
GPNPHLCG_01846 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GPNPHLCG_01847 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
GPNPHLCG_01848 1.5e-180 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
GPNPHLCG_01849 4.4e-233 pepR S Belongs to the peptidase M16 family
GPNPHLCG_01850 2.6e-42 ymxH S YlmC YmxH family
GPNPHLCG_01851 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
GPNPHLCG_01852 1.4e-107 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
GPNPHLCG_01853 3.2e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GPNPHLCG_01854 1.1e-220 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPNPHLCG_01855 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GPNPHLCG_01856 5.6e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GPNPHLCG_01857 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
GPNPHLCG_01858 4.4e-32 S YlzJ-like protein
GPNPHLCG_01859 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
GPNPHLCG_01860 1.4e-133 ymfC K Transcriptional regulator
GPNPHLCG_01861 3.8e-205 ymfD EGP Major facilitator Superfamily
GPNPHLCG_01862 2.3e-232 ymfF S Peptidase M16
GPNPHLCG_01863 4.1e-242 ymfH S zinc protease
GPNPHLCG_01864 5e-128 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
GPNPHLCG_01865 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
GPNPHLCG_01866 2.7e-143 ymfK S Protein of unknown function (DUF3388)
GPNPHLCG_01867 1.9e-124 ymfM S protein conserved in bacteria
GPNPHLCG_01868 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GPNPHLCG_01869 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
GPNPHLCG_01870 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GPNPHLCG_01871 4.4e-214 pbpX V Beta-lactamase
GPNPHLCG_01872 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
GPNPHLCG_01873 1.9e-152 ymdB S protein conserved in bacteria
GPNPHLCG_01874 1.2e-36 spoVS S Stage V sporulation protein S
GPNPHLCG_01875 7.3e-197 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
GPNPHLCG_01876 2.5e-217 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GPNPHLCG_01877 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GPNPHLCG_01878 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
GPNPHLCG_01879 2.2e-88 cotE S Spore coat protein
GPNPHLCG_01880 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GPNPHLCG_01881 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GPNPHLCG_01882 4.9e-68 S Regulatory protein YrvL
GPNPHLCG_01883 1.1e-95 ymcC S Membrane
GPNPHLCG_01884 8.1e-103 pksA K Transcriptional regulator
GPNPHLCG_01885 4.4e-61 ymzB
GPNPHLCG_01886 6.2e-162 ymaE S Metallo-beta-lactamase superfamily
GPNPHLCG_01887 1.2e-249 aprX O Belongs to the peptidase S8 family
GPNPHLCG_01888 1.9e-07 K Transcriptional regulator
GPNPHLCG_01889 1e-125 ymaC S Replication protein
GPNPHLCG_01890 4.6e-79 ymaD O redox protein, regulator of disulfide bond formation
GPNPHLCG_01891 3.1e-54 ebrB P COG2076 Membrane transporters of cations and cationic drugs
GPNPHLCG_01892 5.4e-50 ebrA P Small Multidrug Resistance protein
GPNPHLCG_01894 1e-45 ymaF S YmaF family
GPNPHLCG_01895 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GPNPHLCG_01896 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
GPNPHLCG_01897 8.2e-23
GPNPHLCG_01898 4.5e-22 ymzA
GPNPHLCG_01899 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
GPNPHLCG_01900 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_01901 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_01902 1.7e-108 ymaB
GPNPHLCG_01903 2.8e-113 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNPHLCG_01904 1.7e-176 spoVK O stage V sporulation protein K
GPNPHLCG_01905 2.1e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GPNPHLCG_01906 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
GPNPHLCG_01907 4.3e-68 glnR K transcriptional
GPNPHLCG_01908 3.5e-260 glnA 6.3.1.2 E glutamine synthetase
GPNPHLCG_01909 1.1e-09
GPNPHLCG_01910 4.6e-31
GPNPHLCG_01911 3.7e-38
GPNPHLCG_01912 2.2e-85 G SMI1-KNR4 cell-wall
GPNPHLCG_01913 7.7e-141 ynaC
GPNPHLCG_01914 4.4e-97 ynaD J Acetyltransferase (GNAT) domain
GPNPHLCG_01915 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_01916 3.3e-75 S CAAX protease self-immunity
GPNPHLCG_01918 4.2e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
GPNPHLCG_01919 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_01920 1.8e-254 xynT G MFS/sugar transport protein
GPNPHLCG_01921 1.1e-57 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNPHLCG_01922 7.4e-238 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNPHLCG_01923 1.5e-214 xylR GK ROK family
GPNPHLCG_01924 6.4e-262 xylA 5.3.1.5 G Belongs to the xylose isomerase family
GPNPHLCG_01925 3.6e-290 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
GPNPHLCG_01926 4.9e-111 yokF 3.1.31.1 L RNA catabolic process
GPNPHLCG_01927 2.3e-254 iolT EGP Major facilitator Superfamily
GPNPHLCG_01928 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GPNPHLCG_01929 5.3e-83 yncE S Protein of unknown function (DUF2691)
GPNPHLCG_01930 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GPNPHLCG_01931 5.2e-15
GPNPHLCG_01932 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_01935 1.9e-163 S Thymidylate synthase
GPNPHLCG_01936 5.4e-32
GPNPHLCG_01938 1.5e-127 S Domain of unknown function, YrpD
GPNPHLCG_01941 7.9e-25 tatA U protein secretion
GPNPHLCG_01942 1.3e-51
GPNPHLCG_01943 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
GPNPHLCG_01946 2.8e-52 gerAA EG Spore germination protein
GPNPHLCG_01947 1.5e-145 gerAA EG Spore germination protein
GPNPHLCG_01948 1e-193 gerAB U Spore germination
GPNPHLCG_01949 1.2e-219 gerLC S Spore germination protein
GPNPHLCG_01950 7.2e-152 yndG S DoxX-like family
GPNPHLCG_01951 8e-114 yndH S Domain of unknown function (DUF4166)
GPNPHLCG_01952 1.6e-307 yndJ S YndJ-like protein
GPNPHLCG_01955 1.5e-135 yndL S Replication protein
GPNPHLCG_01956 6.4e-73 yndM S Protein of unknown function (DUF2512)
GPNPHLCG_01957 2.4e-74 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
GPNPHLCG_01958 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GPNPHLCG_01959 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
GPNPHLCG_01960 5e-111 yneB L resolvase
GPNPHLCG_01961 1.3e-32 ynzC S UPF0291 protein
GPNPHLCG_01962 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GPNPHLCG_01963 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
GPNPHLCG_01964 1.8e-28 yneF S UPF0154 protein
GPNPHLCG_01965 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
GPNPHLCG_01966 7.1e-127 ccdA O cytochrome c biogenesis protein
GPNPHLCG_01967 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
GPNPHLCG_01968 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
GPNPHLCG_01969 4.2e-74 yneK S Protein of unknown function (DUF2621)
GPNPHLCG_01970 1.2e-64 hspX O Spore coat protein
GPNPHLCG_01971 3.9e-19 sspP S Belongs to the SspP family
GPNPHLCG_01972 2.2e-14 sspO S Belongs to the SspO family
GPNPHLCG_01973 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GPNPHLCG_01974 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GPNPHLCG_01976 3.1e-08 sspN S Small acid-soluble spore protein N family
GPNPHLCG_01977 1.1e-34 tlp S Belongs to the Tlp family
GPNPHLCG_01978 1.2e-73 yneP S Thioesterase-like superfamily
GPNPHLCG_01979 1.9e-52 yneQ
GPNPHLCG_01980 4.1e-49 yneR S Belongs to the HesB IscA family
GPNPHLCG_01981 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
GPNPHLCG_01982 1.3e-12 yccU S CoA-binding protein
GPNPHLCG_01983 1.3e-41 yccU S CoA-binding protein
GPNPHLCG_01984 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPNPHLCG_01985 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
GPNPHLCG_01986 2.3e-12
GPNPHLCG_01987 8.6e-57 ynfC
GPNPHLCG_01988 9e-251 agcS E Sodium alanine symporter
GPNPHLCG_01989 1.2e-296 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
GPNPHLCG_01991 2.4e-155 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
GPNPHLCG_01992 3.5e-76 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
GPNPHLCG_01993 6.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
GPNPHLCG_01994 3.8e-78 yngA S membrane
GPNPHLCG_01995 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPNPHLCG_01996 5.5e-104 yngC S membrane-associated protein
GPNPHLCG_01997 1.2e-232 nrnB S phosphohydrolase (DHH superfamily)
GPNPHLCG_01998 2e-288 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPNPHLCG_01999 1.7e-134 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPNPHLCG_02000 4.4e-166 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
GPNPHLCG_02001 6.6e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
GPNPHLCG_02002 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
GPNPHLCG_02003 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNPHLCG_02004 3.7e-210 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
GPNPHLCG_02005 8.5e-303 yngK T Glycosyl hydrolase-like 10
GPNPHLCG_02006 2.8e-64 yngL S Protein of unknown function (DUF1360)
GPNPHLCG_02007 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
GPNPHLCG_02008 7.1e-262 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
GPNPHLCG_02009 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_02010 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_02011 6.8e-273 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
GPNPHLCG_02012 1.4e-186 yoxA 5.1.3.3 G Aldose 1-epimerase
GPNPHLCG_02013 2.3e-246 yoeA V MATE efflux family protein
GPNPHLCG_02014 1.8e-98 yoeB S IseA DL-endopeptidase inhibitor
GPNPHLCG_02016 2.2e-96 L Integrase
GPNPHLCG_02017 8.7e-34 yoeD G Helix-turn-helix domain
GPNPHLCG_02018 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GPNPHLCG_02019 2.6e-155 gltR1 K Transcriptional regulator
GPNPHLCG_02020 1.8e-184 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
GPNPHLCG_02021 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
GPNPHLCG_02022 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
GPNPHLCG_02023 7.8e-155 gltC K Transcriptional regulator
GPNPHLCG_02024 6e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GPNPHLCG_02025 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNPHLCG_02026 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
GPNPHLCG_02027 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_02028 6e-38 yoxC S Bacterial protein of unknown function (DUF948)
GPNPHLCG_02029 2.9e-134 yoxB
GPNPHLCG_02030 1.6e-94 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
GPNPHLCG_02031 1.6e-66 V ABC-2 family transporter protein
GPNPHLCG_02032 3.7e-94 V ABC-2 family transporter protein
GPNPHLCG_02033 9.7e-140 V AAA domain, putative AbiEii toxin, Type IV TA system
GPNPHLCG_02034 8.6e-80 hpr K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_02035 1.2e-233 yoaB EGP Major facilitator Superfamily
GPNPHLCG_02036 2.2e-279 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
GPNPHLCG_02037 5.8e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNPHLCG_02038 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNPHLCG_02039 1.1e-33 yoaF
GPNPHLCG_02040 5e-08 ywlA S Uncharacterised protein family (UPF0715)
GPNPHLCG_02041 1e-12
GPNPHLCG_02042 4.1e-36 S Protein of unknown function (DUF4025)
GPNPHLCG_02043 7.7e-133 mcpU NT methyl-accepting chemotaxis protein
GPNPHLCG_02044 6.2e-279 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
GPNPHLCG_02045 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
GPNPHLCG_02046 5.2e-111 yoaK S Membrane
GPNPHLCG_02047 4.3e-197 pelB 4.2.2.10, 4.2.2.2 G Amb_all
GPNPHLCG_02048 1.7e-130 yoqW S Belongs to the SOS response-associated peptidase family
GPNPHLCG_02050 8e-162 oxdC 4.1.1.2 G Oxalate decarboxylase
GPNPHLCG_02051 1.2e-52 oxdC 4.1.1.2 G Oxalate decarboxylase
GPNPHLCG_02054 4.4e-83
GPNPHLCG_02055 4.3e-169 yoaR V vancomycin resistance protein
GPNPHLCG_02056 7.3e-75 yoaS S Protein of unknown function (DUF2975)
GPNPHLCG_02057 4.4e-30 yozG K Transcriptional regulator
GPNPHLCG_02058 2.4e-147 yoaT S Protein of unknown function (DUF817)
GPNPHLCG_02059 2.1e-158 yoaU K LysR substrate binding domain
GPNPHLCG_02060 5.3e-156 yijE EG EamA-like transporter family
GPNPHLCG_02061 1.6e-76 yoaW
GPNPHLCG_02062 1.4e-113 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
GPNPHLCG_02063 1.2e-163 bla 3.5.2.6 V beta-lactamase
GPNPHLCG_02066 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
GPNPHLCG_02067 6.9e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
GPNPHLCG_02068 1.3e-35 S TM2 domain
GPNPHLCG_02069 4.1e-56 K Helix-turn-helix
GPNPHLCG_02072 9.5e-50 FG Scavenger mRNA decapping enzyme C-term binding
GPNPHLCG_02078 4.6e-11 ywlA S Uncharacterised protein family (UPF0715)
GPNPHLCG_02082 4.1e-54 S Tetratricopeptide repeat
GPNPHLCG_02083 5.2e-61 J tRNA cytidylyltransferase activity
GPNPHLCG_02091 1.3e-204 S aspartate phosphatase
GPNPHLCG_02093 1.9e-51 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNPHLCG_02094 5.8e-22 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNPHLCG_02095 4.1e-98 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNPHLCG_02096 8.5e-42 S YolD-like protein
GPNPHLCG_02098 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_02099 2.4e-68
GPNPHLCG_02100 3.5e-90 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPNPHLCG_02102 4.7e-101 S aspartate phosphatase
GPNPHLCG_02104 2.3e-92 yokJ S SMI1 / KNR4 family (SUKH-1)
GPNPHLCG_02105 8.7e-288 UW nuclease activity
GPNPHLCG_02106 8.1e-102 yokH G SMI1 / KNR4 family
GPNPHLCG_02107 2.1e-274 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
GPNPHLCG_02108 1e-198 yobO M Pectate lyase superfamily protein
GPNPHLCG_02109 2.4e-221 yobO M Pectate lyase superfamily protein
GPNPHLCG_02110 9.3e-53 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
GPNPHLCG_02111 3.8e-136 yobQ K helix_turn_helix, arabinose operon control protein
GPNPHLCG_02112 1.2e-140 yobR 2.3.1.1 J FR47-like protein
GPNPHLCG_02113 1.3e-97 yobS K Transcriptional regulator
GPNPHLCG_02114 2.1e-131 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNPHLCG_02115 8.3e-87 yobU K Bacterial transcription activator, effector binding domain
GPNPHLCG_02116 2.7e-174 yobV K WYL domain
GPNPHLCG_02117 2.6e-92 yobW
GPNPHLCG_02118 1e-51 czrA K transcriptional
GPNPHLCG_02119 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
GPNPHLCG_02120 1.5e-92 yozB S membrane
GPNPHLCG_02121 1.1e-141
GPNPHLCG_02122 1.5e-91 yocC
GPNPHLCG_02123 1.8e-184 yocD 3.4.17.13 V peptidase S66
GPNPHLCG_02124 5.3e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
GPNPHLCG_02125 1.7e-196 desK 2.7.13.3 T Histidine kinase
GPNPHLCG_02126 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_02128 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
GPNPHLCG_02129 0.0 recQ 3.6.4.12 L DNA helicase
GPNPHLCG_02131 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPNPHLCG_02132 3.3e-83 dksA T general stress protein
GPNPHLCG_02133 5.4e-53 yocL
GPNPHLCG_02134 6.2e-32
GPNPHLCG_02135 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
GPNPHLCG_02136 1.1e-40 yozN
GPNPHLCG_02137 1.9e-36 yocN
GPNPHLCG_02138 4.2e-56 yozO S Bacterial PH domain
GPNPHLCG_02139 2.7e-31 yozC
GPNPHLCG_02140 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
GPNPHLCG_02141 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
GPNPHLCG_02142 6.6e-164 sodA 1.15.1.1 P Superoxide dismutase
GPNPHLCG_02143 2.2e-230 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
GPNPHLCG_02144 1.1e-167 yocS S -transporter
GPNPHLCG_02145 9.1e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
GPNPHLCG_02146 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
GPNPHLCG_02147 0.0 yojO P Von Willebrand factor
GPNPHLCG_02148 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
GPNPHLCG_02149 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GPNPHLCG_02150 7.9e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
GPNPHLCG_02151 5.9e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
GPNPHLCG_02152 4.1e-107 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
GPNPHLCG_02154 1.1e-242 norM V Multidrug efflux pump
GPNPHLCG_02155 1.6e-149 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPNPHLCG_02156 2.1e-125 yojG S deacetylase
GPNPHLCG_02157 2.2e-60 yojF S Protein of unknown function (DUF1806)
GPNPHLCG_02158 1.5e-43
GPNPHLCG_02159 6.6e-162 rarD S -transporter
GPNPHLCG_02160 2.8e-63 yozR S COG0071 Molecular chaperone (small heat shock protein)
GPNPHLCG_02161 2.6e-09
GPNPHLCG_02162 1.2e-207 gntP EG COG2610 H gluconate symporter and related permeases
GPNPHLCG_02163 4.7e-64 yodA S tautomerase
GPNPHLCG_02164 4.4e-55 yodB K transcriptional
GPNPHLCG_02165 1.4e-107 yodC C nitroreductase
GPNPHLCG_02166 4.2e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_02167 3.2e-45 L transposase activity
GPNPHLCG_02168 2.7e-111 mhqD S Carboxylesterase
GPNPHLCG_02169 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
GPNPHLCG_02170 6.2e-28 S Protein of unknown function (DUF3311)
GPNPHLCG_02171 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_02172 3.2e-45 L transposase activity
GPNPHLCG_02173 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_02174 3.4e-250 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
GPNPHLCG_02175 2.4e-127 yodH Q Methyltransferase
GPNPHLCG_02176 1.5e-23 yodI
GPNPHLCG_02177 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
GPNPHLCG_02178 1.2e-126 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
GPNPHLCG_02179 5.3e-09
GPNPHLCG_02180 3.6e-54 yodL S YodL-like
GPNPHLCG_02181 1e-105 yodM 3.6.1.27 I Acid phosphatase homologues
GPNPHLCG_02182 2.8e-24 yozD S YozD-like protein
GPNPHLCG_02184 1.3e-122 yodN
GPNPHLCG_02185 3.1e-36 yozE S Belongs to the UPF0346 family
GPNPHLCG_02186 8.3e-47 yokU S YokU-like protein, putative antitoxin
GPNPHLCG_02187 1.2e-274 kamA 5.4.3.2 E lysine 2,3-aminomutase
GPNPHLCG_02188 3.9e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
GPNPHLCG_02189 2.1e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
GPNPHLCG_02190 6.8e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPNPHLCG_02191 4.9e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPNPHLCG_02192 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNPHLCG_02194 1.8e-144 yiiD K acetyltransferase
GPNPHLCG_02195 1.9e-255 cgeD M maturation of the outermost layer of the spore
GPNPHLCG_02196 5.9e-38 cgeC
GPNPHLCG_02197 4.8e-64 cgeA
GPNPHLCG_02198 1.4e-186 cgeB S Spore maturation protein
GPNPHLCG_02199 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
GPNPHLCG_02200 2.5e-63 4.2.1.115 GM Polysaccharide biosynthesis protein
GPNPHLCG_02202 2.7e-100 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPNPHLCG_02203 1.3e-10 K Cro/C1-type HTH DNA-binding domain
GPNPHLCG_02216 6.5e-164 S Calcineurin-like phosphoesterase
GPNPHLCG_02217 2.5e-30 sspB S spore protein
GPNPHLCG_02220 7e-36
GPNPHLCG_02223 4.4e-160 S Thymidylate synthase
GPNPHLCG_02227 3e-42 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
GPNPHLCG_02229 3.6e-73 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GPNPHLCG_02230 8.1e-10
GPNPHLCG_02231 1.5e-36 O Glutaredoxin
GPNPHLCG_02232 1.1e-65 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_02233 2.6e-86 L HNH endonuclease
GPNPHLCG_02234 6.3e-105 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_02236 8.8e-214 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_02237 3.4e-116 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_02238 7.9e-67 S NrdI Flavodoxin like
GPNPHLCG_02242 1.3e-12 larC 4.99.1.12 FJ Protein conserved in bacteria
GPNPHLCG_02255 2.4e-67 S N-methyltransferase activity
GPNPHLCG_02256 6e-68 2.1.1.113, 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
GPNPHLCG_02257 3.5e-91 yorS 3.1.3.5 S 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
GPNPHLCG_02258 1.4e-81 tmk 2.1.1.45, 2.7.4.9 F dTDP biosynthetic process
GPNPHLCG_02261 3.9e-23 S protein conserved in bacteria
GPNPHLCG_02262 0.0 2.7.7.7 L DNA polymerase
GPNPHLCG_02263 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPNPHLCG_02264 3.6e-213 L DNA primase activity
GPNPHLCG_02265 9.7e-283 3.6.4.12 J DnaB-like helicase C terminal domain
GPNPHLCG_02266 5.3e-86
GPNPHLCG_02267 7.6e-180 L AAA domain
GPNPHLCG_02268 2.5e-156
GPNPHLCG_02270 1.5e-08
GPNPHLCG_02275 2.2e-154
GPNPHLCG_02277 4.6e-138 ligB 6.5.1.1, 6.5.1.6, 6.5.1.7 L ATP-dependent DNA ligase
GPNPHLCG_02278 7.6e-65
GPNPHLCG_02279 1.7e-08 xtmA L phage terminase small subunit
GPNPHLCG_02280 5.4e-62
GPNPHLCG_02281 1.1e-53 O peptidyl-tyrosine sulfation
GPNPHLCG_02288 1.8e-92 S Protein of unknown function (DUF1273)
GPNPHLCG_02292 8.8e-12 S Protein of unknown function (DUF2815)
GPNPHLCG_02293 3.1e-274 3.1.3.16, 3.1.4.37 T phosphatase
GPNPHLCG_02295 6.8e-64
GPNPHLCG_02297 7.2e-10 S YopX protein
GPNPHLCG_02302 3.9e-15 K Transcriptional regulator
GPNPHLCG_02303 1.4e-32
GPNPHLCG_02304 3.3e-250
GPNPHLCG_02305 2.9e-39 L Belongs to the 'phage' integrase family
GPNPHLCG_02311 4.3e-81
GPNPHLCG_02313 8.5e-16
GPNPHLCG_02314 1.2e-20
GPNPHLCG_02318 1.2e-18
GPNPHLCG_02324 8.9e-202 3.1.21.3 L Domain of unknown function (DUF4942)
GPNPHLCG_02326 1.3e-232 S DNA replication origin binding
GPNPHLCG_02328 3.1e-36
GPNPHLCG_02332 0.0 S RNA-directed RNA polymerase activity
GPNPHLCG_02333 5.8e-94
GPNPHLCG_02334 1.4e-30 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPNPHLCG_02336 2.5e-228 S hydrolase activity
GPNPHLCG_02339 1.8e-175
GPNPHLCG_02340 0.0 gp17a S Terminase-like family
GPNPHLCG_02341 1.3e-279
GPNPHLCG_02342 8.7e-265
GPNPHLCG_02343 1.7e-93
GPNPHLCG_02344 1.3e-185
GPNPHLCG_02345 1.1e-80
GPNPHLCG_02346 3.2e-68
GPNPHLCG_02348 1.4e-121
GPNPHLCG_02349 1.7e-77
GPNPHLCG_02350 1.8e-72
GPNPHLCG_02351 1.9e-59
GPNPHLCG_02354 8.4e-52
GPNPHLCG_02355 6.3e-30
GPNPHLCG_02358 4.1e-57
GPNPHLCG_02359 8.9e-61
GPNPHLCG_02360 1.2e-191 xerH A Belongs to the 'phage' integrase family
GPNPHLCG_02362 1e-18
GPNPHLCG_02363 1e-20
GPNPHLCG_02364 0.0 S peptidoglycan catabolic process
GPNPHLCG_02365 6.2e-145 S Phage tail protein
GPNPHLCG_02366 0.0 S Pfam Transposase IS66
GPNPHLCG_02367 1.6e-98
GPNPHLCG_02368 5.4e-56 S outer membrane
GPNPHLCG_02369 2.9e-161
GPNPHLCG_02370 1.9e-182 S N-acetylmuramoyl-L-alanine amidase activity
GPNPHLCG_02372 2.4e-37 S Bacteriophage holin
GPNPHLCG_02373 1.6e-189 S aspartate phosphatase
GPNPHLCG_02375 2.5e-184 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_02376 5.3e-234 S impB/mucB/samB family C-terminal domain
GPNPHLCG_02377 4.6e-52 S YolD-like protein
GPNPHLCG_02378 4e-59 L nuclease activity
GPNPHLCG_02380 1.6e-63 S SMI1-KNR4 cell-wall
GPNPHLCG_02381 1.8e-275 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GPNPHLCG_02382 1.4e-71 yokH G SMI1 / KNR4 family
GPNPHLCG_02383 4e-306 yokA L Recombinase
GPNPHLCG_02384 1.4e-96 4.2.1.115 GM Polysaccharide biosynthesis protein
GPNPHLCG_02385 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPNPHLCG_02386 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPNPHLCG_02387 1.6e-70 ypoP K transcriptional
GPNPHLCG_02388 1.9e-221 mepA V MATE efflux family protein
GPNPHLCG_02389 1.2e-28 ypmT S Uncharacterized ympT
GPNPHLCG_02390 1.1e-98 ypmS S protein conserved in bacteria
GPNPHLCG_02391 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_02392 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GPNPHLCG_02393 3.1e-40 ypmP S Protein of unknown function (DUF2535)
GPNPHLCG_02394 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPNPHLCG_02395 3.4e-183 pspF K Transcriptional regulator
GPNPHLCG_02396 4.2e-110 hlyIII S protein, Hemolysin III
GPNPHLCG_02397 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GPNPHLCG_02398 1.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPNPHLCG_02399 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPNPHLCG_02400 4.3e-112 ypjP S YpjP-like protein
GPNPHLCG_02401 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
GPNPHLCG_02402 1.7e-75 yphP S Belongs to the UPF0403 family
GPNPHLCG_02403 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GPNPHLCG_02404 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
GPNPHLCG_02405 3.5e-106 ypgQ S phosphohydrolase
GPNPHLCG_02406 9.2e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
GPNPHLCG_02407 4.7e-176 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPNPHLCG_02408 2.3e-215 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GPNPHLCG_02409 1e-30 cspD K Cold-shock protein
GPNPHLCG_02410 3.8e-16 degR
GPNPHLCG_02411 8.1e-31 S Protein of unknown function (DUF2564)
GPNPHLCG_02412 3e-29 ypeQ S Zinc-finger
GPNPHLCG_02413 6.4e-125 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
GPNPHLCG_02414 6.3e-120 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
GPNPHLCG_02415 2.7e-67 rnhA 3.1.26.4 L Ribonuclease
GPNPHLCG_02417 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
GPNPHLCG_02418 2e-07
GPNPHLCG_02419 1e-38 ypbS S Protein of unknown function (DUF2533)
GPNPHLCG_02420 0.0 ypbR S Dynamin family
GPNPHLCG_02421 5.1e-87 ypbQ S protein conserved in bacteria
GPNPHLCG_02422 7.7e-205 bcsA Q Naringenin-chalcone synthase
GPNPHLCG_02423 1.5e-226 pbuX F xanthine
GPNPHLCG_02424 1.1e-98 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
GPNPHLCG_02425 4.6e-293 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
GPNPHLCG_02426 1.2e-169 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
GPNPHLCG_02427 3e-102 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
GPNPHLCG_02428 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
GPNPHLCG_02429 3.9e-187 ptxS K transcriptional
GPNPHLCG_02430 4.8e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
GPNPHLCG_02431 3.7e-129 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_02432 3.6e-293 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
GPNPHLCG_02433 1.5e-60 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
GPNPHLCG_02435 9.2e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
GPNPHLCG_02436 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
GPNPHLCG_02437 5.3e-90 ypsA S Belongs to the UPF0398 family
GPNPHLCG_02438 1e-215 yprB L RNase_H superfamily
GPNPHLCG_02439 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
GPNPHLCG_02440 1.6e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
GPNPHLCG_02441 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
GPNPHLCG_02442 1.2e-48 yppG S YppG-like protein
GPNPHLCG_02444 5.7e-11 yppE S Bacterial domain of unknown function (DUF1798)
GPNPHLCG_02447 3.5e-185 yppC S Protein of unknown function (DUF2515)
GPNPHLCG_02448 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPNPHLCG_02449 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
GPNPHLCG_02450 4.7e-93 ypoC
GPNPHLCG_02451 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GPNPHLCG_02452 5.7e-129 dnaD L DNA replication protein DnaD
GPNPHLCG_02453 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
GPNPHLCG_02454 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
GPNPHLCG_02455 4.9e-79 ypmB S protein conserved in bacteria
GPNPHLCG_02456 1.9e-22 ypmA S Protein of unknown function (DUF4264)
GPNPHLCG_02457 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
GPNPHLCG_02458 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GPNPHLCG_02459 6.1e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GPNPHLCG_02460 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
GPNPHLCG_02461 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
GPNPHLCG_02462 2.7e-219 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
GPNPHLCG_02463 3.8e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
GPNPHLCG_02464 1.7e-128 bshB1 S proteins, LmbE homologs
GPNPHLCG_02465 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
GPNPHLCG_02466 1.8e-147 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
GPNPHLCG_02467 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
GPNPHLCG_02468 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
GPNPHLCG_02469 1.5e-141 ypjB S sporulation protein
GPNPHLCG_02470 2.4e-99 ypjA S membrane
GPNPHLCG_02471 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
GPNPHLCG_02472 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
GPNPHLCG_02473 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
GPNPHLCG_02474 1e-75 ypiF S Protein of unknown function (DUF2487)
GPNPHLCG_02475 2.8e-99 ypiB S Belongs to the UPF0302 family
GPNPHLCG_02476 4.1e-234 S COG0457 FOG TPR repeat
GPNPHLCG_02477 3.4e-236 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
GPNPHLCG_02478 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
GPNPHLCG_02479 4.2e-203 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GPNPHLCG_02480 9.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
GPNPHLCG_02481 1.5e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
GPNPHLCG_02482 1e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
GPNPHLCG_02483 1.4e-112 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
GPNPHLCG_02484 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GPNPHLCG_02485 6.6e-295 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GPNPHLCG_02486 1e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
GPNPHLCG_02487 6.5e-204 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GPNPHLCG_02488 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GPNPHLCG_02489 1.1e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
GPNPHLCG_02490 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
GPNPHLCG_02491 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPNPHLCG_02492 8.6e-133 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
GPNPHLCG_02493 5.6e-138 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
GPNPHLCG_02494 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
GPNPHLCG_02495 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
GPNPHLCG_02496 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
GPNPHLCG_02497 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
GPNPHLCG_02498 2.3e-136 yphF
GPNPHLCG_02499 1.6e-18 yphE S Protein of unknown function (DUF2768)
GPNPHLCG_02500 9.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
GPNPHLCG_02501 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
GPNPHLCG_02502 2.1e-28 ypzH
GPNPHLCG_02503 3.3e-161 seaA S YIEGIA protein
GPNPHLCG_02504 4.8e-100 yphA
GPNPHLCG_02505 1e-07 S YpzI-like protein
GPNPHLCG_02506 1.3e-182 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
GPNPHLCG_02507 1.4e-204 rpsA 1.17.7.4 J Ribosomal protein S1
GPNPHLCG_02508 2.8e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
GPNPHLCG_02509 1.8e-23 S Family of unknown function (DUF5359)
GPNPHLCG_02510 3.1e-108 ypfA M Flagellar protein YcgR
GPNPHLCG_02511 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
GPNPHLCG_02512 5.7e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
GPNPHLCG_02513 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
GPNPHLCG_02514 2.1e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
GPNPHLCG_02515 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNPHLCG_02516 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
GPNPHLCG_02517 5.7e-146 ypbG S Calcineurin-like phosphoesterase superfamily domain
GPNPHLCG_02518 2.8e-81 ypbF S Protein of unknown function (DUF2663)
GPNPHLCG_02519 3.8e-75 ypbE M Lysin motif
GPNPHLCG_02520 1.1e-99 ypbD S metal-dependent membrane protease
GPNPHLCG_02521 2.3e-284 recQ 3.6.4.12 L DNA helicase
GPNPHLCG_02522 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
GPNPHLCG_02523 4.7e-41 fer C Ferredoxin
GPNPHLCG_02524 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GPNPHLCG_02525 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNPHLCG_02526 5e-134 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
GPNPHLCG_02527 3.8e-188 rsiX
GPNPHLCG_02528 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_02529 0.0 resE 2.7.13.3 T Histidine kinase
GPNPHLCG_02530 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_02531 5.3e-212 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
GPNPHLCG_02532 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
GPNPHLCG_02533 3.6e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
GPNPHLCG_02534 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPNPHLCG_02535 1.9e-87 spmB S Spore maturation protein
GPNPHLCG_02536 3.5e-103 spmA S Spore maturation protein
GPNPHLCG_02537 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
GPNPHLCG_02538 4e-98 ypuI S Protein of unknown function (DUF3907)
GPNPHLCG_02539 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GPNPHLCG_02540 6.4e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GPNPHLCG_02541 1e-90 ypuF S Domain of unknown function (DUF309)
GPNPHLCG_02542 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_02543 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
GPNPHLCG_02544 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GPNPHLCG_02545 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
GPNPHLCG_02546 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GPNPHLCG_02547 7.8e-55 ypuD
GPNPHLCG_02548 1.1e-95 sipT 3.4.21.89 U Belongs to the peptidase S26 family
GPNPHLCG_02549 6.6e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
GPNPHLCG_02551 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GPNPHLCG_02552 3.6e-149 ypuA S Secreted protein
GPNPHLCG_02553 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
GPNPHLCG_02554 1.7e-271 spoVAF EG Stage V sporulation protein AF
GPNPHLCG_02555 1.4e-110 spoVAEA S stage V sporulation protein
GPNPHLCG_02556 2.2e-57 spoVAEB S stage V sporulation protein
GPNPHLCG_02557 9e-192 spoVAD I Stage V sporulation protein AD
GPNPHLCG_02558 2.3e-78 spoVAC S stage V sporulation protein AC
GPNPHLCG_02559 1e-67 spoVAB S Stage V sporulation protein AB
GPNPHLCG_02560 9.6e-112 spoVAA S Stage V sporulation protein AA
GPNPHLCG_02561 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_02562 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
GPNPHLCG_02563 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
GPNPHLCG_02564 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
GPNPHLCG_02565 1.4e-147 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GPNPHLCG_02566 6.7e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
GPNPHLCG_02567 2.6e-166 xerD L recombinase XerD
GPNPHLCG_02568 1.4e-36 S Protein of unknown function (DUF4227)
GPNPHLCG_02569 2.4e-80 fur P Belongs to the Fur family
GPNPHLCG_02570 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
GPNPHLCG_02571 2.2e-31 yqkK
GPNPHLCG_02572 5.5e-242 mleA 1.1.1.38 C malic enzyme
GPNPHLCG_02573 3.1e-235 mleN C Na H antiporter
GPNPHLCG_02574 1.9e-267 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
GPNPHLCG_02575 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
GPNPHLCG_02576 1.3e-57 ansR K Transcriptional regulator
GPNPHLCG_02577 3.4e-219 yqxK 3.6.4.12 L DNA helicase
GPNPHLCG_02578 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
GPNPHLCG_02580 1.6e-166 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
GPNPHLCG_02581 1.4e-45 L transposase activity
GPNPHLCG_02582 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_02583 9.1e-12 yqkE S Protein of unknown function (DUF3886)
GPNPHLCG_02584 1.2e-171 yqkD S COG1073 Hydrolases of the alpha beta superfamily
GPNPHLCG_02585 9.4e-39 yqkC S Protein of unknown function (DUF2552)
GPNPHLCG_02586 2.8e-54 yqkB S Belongs to the HesB IscA family
GPNPHLCG_02587 2.2e-193 yqkA K GrpB protein
GPNPHLCG_02588 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
GPNPHLCG_02589 8.1e-87 yqjY K acetyltransferase
GPNPHLCG_02590 1.7e-49 S YolD-like protein
GPNPHLCG_02591 2e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNPHLCG_02593 2.6e-225 yqjV G Major Facilitator Superfamily
GPNPHLCG_02595 2.3e-71 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNPHLCG_02596 3.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
GPNPHLCG_02597 6e-260 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
GPNPHLCG_02598 6.6e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_02599 8.3e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNPHLCG_02600 1.1e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNPHLCG_02601 0.0 rocB E arginine degradation protein
GPNPHLCG_02602 5.3e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
GPNPHLCG_02603 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
GPNPHLCG_02604 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPNPHLCG_02605 8.5e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
GPNPHLCG_02606 1.4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GPNPHLCG_02607 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPNPHLCG_02608 1.6e-235 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GPNPHLCG_02609 4.5e-24 yqzJ
GPNPHLCG_02610 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPNPHLCG_02611 9.8e-140 yqjF S Uncharacterized conserved protein (COG2071)
GPNPHLCG_02612 1.4e-201 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
GPNPHLCG_02613 2.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
GPNPHLCG_02614 8.7e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
GPNPHLCG_02616 1.4e-98 yqjB S protein conserved in bacteria
GPNPHLCG_02617 1.1e-173 yqjA S Putative aromatic acid exporter C-terminal domain
GPNPHLCG_02618 7.7e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNPHLCG_02619 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
GPNPHLCG_02620 1.8e-136 artP ET Belongs to the bacterial solute-binding protein 3 family
GPNPHLCG_02621 9.3e-77 yqiW S Belongs to the UPF0403 family
GPNPHLCG_02622 3.4e-166 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
GPNPHLCG_02623 7.9e-208 norA EGP Major facilitator Superfamily
GPNPHLCG_02624 1.4e-150 bmrR K helix_turn_helix, mercury resistance
GPNPHLCG_02625 5.4e-226 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
GPNPHLCG_02626 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
GPNPHLCG_02627 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
GPNPHLCG_02628 2.2e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
GPNPHLCG_02629 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
GPNPHLCG_02630 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNPHLCG_02631 1.7e-154 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
GPNPHLCG_02632 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
GPNPHLCG_02633 4e-34 yqzF S Protein of unknown function (DUF2627)
GPNPHLCG_02634 4.8e-160 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
GPNPHLCG_02635 1.8e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
GPNPHLCG_02636 2.1e-205 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
GPNPHLCG_02637 1.8e-209 mmgC I acyl-CoA dehydrogenase
GPNPHLCG_02638 1.8e-153 hbdA 1.1.1.157 I Dehydrogenase
GPNPHLCG_02639 5.9e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
GPNPHLCG_02640 3.1e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
GPNPHLCG_02641 1.2e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
GPNPHLCG_02642 6e-27
GPNPHLCG_02644 1.2e-211 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
GPNPHLCG_02646 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
GPNPHLCG_02647 2.3e-237 rseP 3.4.21.116 M Stage IV sporulation protein B
GPNPHLCG_02648 3.2e-306 recN L May be involved in recombinational repair of damaged DNA
GPNPHLCG_02649 6.6e-78 argR K Regulates arginine biosynthesis genes
GPNPHLCG_02650 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
GPNPHLCG_02651 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GPNPHLCG_02652 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
GPNPHLCG_02653 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPNPHLCG_02654 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
GPNPHLCG_02655 1.1e-155 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GPNPHLCG_02656 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GPNPHLCG_02657 2.1e-67 yqhY S protein conserved in bacteria
GPNPHLCG_02658 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
GPNPHLCG_02659 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
GPNPHLCG_02660 2.9e-90 spoIIIAH S SpoIIIAH-like protein
GPNPHLCG_02661 2.2e-109 spoIIIAG S stage III sporulation protein AG
GPNPHLCG_02662 1.2e-101 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
GPNPHLCG_02663 1.3e-197 spoIIIAE S stage III sporulation protein AE
GPNPHLCG_02664 2.3e-58 spoIIIAD S Stage III sporulation protein AD
GPNPHLCG_02665 7.6e-29 spoIIIAC S stage III sporulation protein AC
GPNPHLCG_02666 1.1e-84 spoIIIAB S Stage III sporulation protein
GPNPHLCG_02667 4e-170 spoIIIAA S stage III sporulation protein AA
GPNPHLCG_02668 1.8e-36 yqhV S Protein of unknown function (DUF2619)
GPNPHLCG_02669 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GPNPHLCG_02670 1.7e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
GPNPHLCG_02671 3.6e-76 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
GPNPHLCG_02672 6.6e-93 yqhR S Conserved membrane protein YqhR
GPNPHLCG_02673 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
GPNPHLCG_02674 2.2e-61 yqhP
GPNPHLCG_02675 4e-164 yqhO S esterase of the alpha-beta hydrolase superfamily
GPNPHLCG_02676 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
GPNPHLCG_02677 1.3e-159 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
GPNPHLCG_02678 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
GPNPHLCG_02679 5.3e-286 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPNPHLCG_02680 2.4e-253 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GPNPHLCG_02681 9e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
GPNPHLCG_02682 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPNPHLCG_02683 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
GPNPHLCG_02684 1.2e-24 sinI S Anti-repressor SinI
GPNPHLCG_02685 1e-54 sinR K transcriptional
GPNPHLCG_02686 2.3e-142 tasA S Cell division protein FtsN
GPNPHLCG_02687 2.5e-58 sipW 3.4.21.89 U Signal peptidase
GPNPHLCG_02688 2.4e-109 yqxM
GPNPHLCG_02689 7.3e-54 yqzG S Protein of unknown function (DUF3889)
GPNPHLCG_02690 1.4e-26 yqzE S YqzE-like protein
GPNPHLCG_02691 1.8e-44 S ComG operon protein 7
GPNPHLCG_02692 2.7e-45 comGF U Putative Competence protein ComGF
GPNPHLCG_02693 1.3e-57 comGE
GPNPHLCG_02694 2.2e-70 gspH NU protein transport across the cell outer membrane
GPNPHLCG_02695 1.4e-47 comGC U Required for transformation and DNA binding
GPNPHLCG_02696 4.3e-173 comGB NU COG1459 Type II secretory pathway, component PulF
GPNPHLCG_02697 8.6e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GPNPHLCG_02698 6.7e-173 corA P Mg2 transporter protein
GPNPHLCG_02699 1.3e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GPNPHLCG_02700 1.5e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
GPNPHLCG_02702 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
GPNPHLCG_02703 1.8e-37 yqgY S Protein of unknown function (DUF2626)
GPNPHLCG_02704 2.3e-121 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNPHLCG_02705 8.9e-23 yqgW S Protein of unknown function (DUF2759)
GPNPHLCG_02706 6.9e-50 yqgV S Thiamine-binding protein
GPNPHLCG_02707 8.8e-198 yqgU
GPNPHLCG_02708 1.6e-221 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
GPNPHLCG_02709 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNPHLCG_02710 3.4e-180 glcK 2.7.1.2 G Glucokinase
GPNPHLCG_02711 4.5e-32 yqgQ S Protein conserved in bacteria
GPNPHLCG_02712 3.1e-260 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
GPNPHLCG_02713 2.5e-09 yqgO
GPNPHLCG_02714 2.3e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GPNPHLCG_02715 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
GPNPHLCG_02716 8.7e-201 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
GPNPHLCG_02718 3.5e-50 yqzD
GPNPHLCG_02719 7.3e-72 yqzC S YceG-like family
GPNPHLCG_02720 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPNPHLCG_02721 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
GPNPHLCG_02722 4.4e-158 pstA P Phosphate transport system permease
GPNPHLCG_02723 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
GPNPHLCG_02724 8.3e-143 pstS P Phosphate
GPNPHLCG_02725 0.0 pbpA 3.4.16.4 M penicillin-binding protein
GPNPHLCG_02726 2.5e-231 yqgE EGP Major facilitator superfamily
GPNPHLCG_02727 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
GPNPHLCG_02728 2e-72 yqgC S protein conserved in bacteria
GPNPHLCG_02729 3.9e-131 yqgB S Protein of unknown function (DUF1189)
GPNPHLCG_02730 5.2e-47 yqfZ M LysM domain
GPNPHLCG_02731 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GPNPHLCG_02732 2.8e-61 yqfX S membrane
GPNPHLCG_02733 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
GPNPHLCG_02734 1.9e-77 zur P Belongs to the Fur family
GPNPHLCG_02735 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
GPNPHLCG_02736 2.1e-36 yqfT S Protein of unknown function (DUF2624)
GPNPHLCG_02737 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
GPNPHLCG_02738 6.5e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
GPNPHLCG_02739 1.9e-13 yqfQ S YqfQ-like protein
GPNPHLCG_02740 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GPNPHLCG_02741 1.4e-45 L transposase activity
GPNPHLCG_02742 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_02743 2.6e-208 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GPNPHLCG_02744 5.7e-115 trmK 2.1.1.217 S SAM-dependent methyltransferase
GPNPHLCG_02745 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
GPNPHLCG_02746 4.4e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
GPNPHLCG_02747 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
GPNPHLCG_02748 4.5e-88 yaiI S Belongs to the UPF0178 family
GPNPHLCG_02749 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
GPNPHLCG_02750 4.5e-112 ccpN K CBS domain
GPNPHLCG_02751 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
GPNPHLCG_02752 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
GPNPHLCG_02753 9e-144 recO L Involved in DNA repair and RecF pathway recombination
GPNPHLCG_02754 8.4e-19 S YqzL-like protein
GPNPHLCG_02755 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GPNPHLCG_02756 3.5e-70 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
GPNPHLCG_02757 4.3e-59 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
GPNPHLCG_02758 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GPNPHLCG_02759 0.0 yqfF S membrane-associated HD superfamily hydrolase
GPNPHLCG_02761 2.5e-175 phoH T Phosphate starvation-inducible protein PhoH
GPNPHLCG_02762 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
GPNPHLCG_02763 2.7e-45 yqfC S sporulation protein YqfC
GPNPHLCG_02764 1.1e-21 yqfB
GPNPHLCG_02765 3.7e-121 yqfA S UPF0365 protein
GPNPHLCG_02766 2.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
GPNPHLCG_02767 8.3e-65 yqeY S Yqey-like protein
GPNPHLCG_02768 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
GPNPHLCG_02769 4.1e-157 yqeW P COG1283 Na phosphate symporter
GPNPHLCG_02770 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
GPNPHLCG_02771 2.7e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
GPNPHLCG_02772 1.6e-174 prmA J Methylates ribosomal protein L11
GPNPHLCG_02773 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
GPNPHLCG_02774 0.0 dnaK O Heat shock 70 kDa protein
GPNPHLCG_02775 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GPNPHLCG_02776 8.9e-187 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
GPNPHLCG_02777 7e-217 hemN H Involved in the biosynthesis of porphyrin-containing compound
GPNPHLCG_02778 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
GPNPHLCG_02779 7.2e-53 yqxA S Protein of unknown function (DUF3679)
GPNPHLCG_02780 1.5e-222 spoIIP M stage II sporulation protein P
GPNPHLCG_02781 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
GPNPHLCG_02782 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
GPNPHLCG_02783 1.9e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
GPNPHLCG_02784 4.1e-15 S YqzM-like protein
GPNPHLCG_02785 3e-122 comEC S Competence protein ComEC
GPNPHLCG_02786 3.4e-259 comEC S Competence protein ComEC
GPNPHLCG_02787 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
GPNPHLCG_02788 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
GPNPHLCG_02789 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GPNPHLCG_02790 3.2e-138 yqeM Q Methyltransferase
GPNPHLCG_02791 3.4e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
GPNPHLCG_02792 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
GPNPHLCG_02793 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GPNPHLCG_02794 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
GPNPHLCG_02795 1.7e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GPNPHLCG_02796 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
GPNPHLCG_02797 5.3e-95 yqeG S hydrolase of the HAD superfamily
GPNPHLCG_02799 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_02800 1.8e-133 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNPHLCG_02801 8.8e-105 yqeD S SNARE associated Golgi protein
GPNPHLCG_02802 5e-170 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
GPNPHLCG_02803 5.7e-132 yqeB
GPNPHLCG_02804 2.4e-74 nucB M Deoxyribonuclease NucA/NucB
GPNPHLCG_02805 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GPNPHLCG_02806 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_02807 3.3e-113 tetR3 K Transcriptional regulator
GPNPHLCG_02808 1.9e-118 mepA V Multidrug transporter MatE
GPNPHLCG_02809 5.3e-70 mepA V Multidrug transporter MatE
GPNPHLCG_02810 6e-165 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
GPNPHLCG_02811 2.1e-111 yrkJ S membrane transporter protein
GPNPHLCG_02812 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
GPNPHLCG_02813 9.3e-206 yrkH P Rhodanese Homology Domain
GPNPHLCG_02814 4.7e-16 perX S Sulfur reduction protein DsrE
GPNPHLCG_02815 4.2e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
GPNPHLCG_02816 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
GPNPHLCG_02817 7.8e-39 yrkD S protein conserved in bacteria
GPNPHLCG_02818 6.6e-21
GPNPHLCG_02819 1.8e-104 yrkC G Cupin domain
GPNPHLCG_02820 3.1e-150 bltR K helix_turn_helix, mercury resistance
GPNPHLCG_02821 1e-210 blt EGP Major facilitator Superfamily
GPNPHLCG_02822 1.5e-82 bltD 2.3.1.57 K FR47-like protein
GPNPHLCG_02823 1.1e-234 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
GPNPHLCG_02824 3.9e-16 S YrzO-like protein
GPNPHLCG_02825 1.9e-170 yrdR EG EamA-like transporter family
GPNPHLCG_02826 6.6e-159 yrdQ K Transcriptional regulator
GPNPHLCG_02827 3.6e-196 trkA P Oxidoreductase
GPNPHLCG_02828 2.6e-153 czcD P COG1230 Co Zn Cd efflux system component
GPNPHLCG_02829 4.2e-65 yodA S tautomerase
GPNPHLCG_02830 5e-162 gltR K LysR substrate binding domain
GPNPHLCG_02831 1.1e-226 brnQ E Component of the transport system for branched-chain amino acids
GPNPHLCG_02832 5.6e-50 azlD E Branched-chain amino acid transport protein (AzlD)
GPNPHLCG_02833 2.2e-91 azlC E AzlC protein
GPNPHLCG_02834 6.3e-79 bkdR K helix_turn_helix ASNC type
GPNPHLCG_02835 1.2e-15 yrdF K ribonuclease inhibitor
GPNPHLCG_02836 2e-225 cypA C Cytochrome P450
GPNPHLCG_02837 6.5e-22 K Acetyltransferase (GNAT) family
GPNPHLCG_02838 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
GPNPHLCG_02839 1.9e-57 S Protein of unknown function (DUF2568)
GPNPHLCG_02841 6.4e-90 yrdA S DinB family
GPNPHLCG_02842 1e-164 aadK G Streptomycin adenylyltransferase
GPNPHLCG_02843 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
GPNPHLCG_02844 3.1e-147 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPNPHLCG_02845 4.8e-123 yrpD S Domain of unknown function, YrpD
GPNPHLCG_02847 1.3e-113 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
GPNPHLCG_02848 1.2e-91 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_02849 1.7e-187 yrpG C Aldo/keto reductase family
GPNPHLCG_02850 5.9e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
GPNPHLCG_02851 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_02852 1.7e-148 S Alpha beta hydrolase
GPNPHLCG_02853 4.9e-60 T sh3 domain protein
GPNPHLCG_02854 2.4e-61 T sh3 domain protein
GPNPHLCG_02856 3.8e-66 E Glyoxalase-like domain
GPNPHLCG_02857 1.5e-36 yraG
GPNPHLCG_02858 4.2e-62 yraF M Spore coat protein
GPNPHLCG_02859 1.4e-222 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNPHLCG_02860 7.5e-26 yraE
GPNPHLCG_02861 1.1e-47 yraD M Spore coat protein
GPNPHLCG_02862 4.4e-47 yraB K helix_turn_helix, mercury resistance
GPNPHLCG_02863 1.8e-195 adhA 1.1.1.1 C alcohol dehydrogenase
GPNPHLCG_02864 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
GPNPHLCG_02865 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
GPNPHLCG_02866 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
GPNPHLCG_02867 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
GPNPHLCG_02868 2.4e-81 levE 2.7.1.202 G PTS system mannose fructose sorbose family
GPNPHLCG_02869 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
GPNPHLCG_02870 0.0 levR K PTS system fructose IIA component
GPNPHLCG_02871 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_02872 1.1e-105 yrhP E LysE type translocator
GPNPHLCG_02873 3.5e-149 yrhO K Archaeal transcriptional regulator TrmB
GPNPHLCG_02874 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_02875 3.2e-150 rsiV S Protein of unknown function (DUF3298)
GPNPHLCG_02876 0.0 yrhL I Acyltransferase family
GPNPHLCG_02877 9e-44 yrhK S YrhK-like protein
GPNPHLCG_02878 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
GPNPHLCG_02879 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
GPNPHLCG_02880 7.2e-95 yrhH Q methyltransferase
GPNPHLCG_02883 1.8e-142 focA P Formate nitrite
GPNPHLCG_02885 2.3e-60 yrhF S Uncharacterized conserved protein (DUF2294)
GPNPHLCG_02886 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
GPNPHLCG_02887 7.1e-78 yrhD S Protein of unknown function (DUF1641)
GPNPHLCG_02888 4.6e-35 yrhC S YrhC-like protein
GPNPHLCG_02889 4.8e-210 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
GPNPHLCG_02890 2e-169 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
GPNPHLCG_02891 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GPNPHLCG_02892 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
GPNPHLCG_02893 1e-25 yrzA S Protein of unknown function (DUF2536)
GPNPHLCG_02894 4.2e-63 yrrS S Protein of unknown function (DUF1510)
GPNPHLCG_02895 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
GPNPHLCG_02896 1.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
GPNPHLCG_02897 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
GPNPHLCG_02898 1.4e-245 yegQ O COG0826 Collagenase and related proteases
GPNPHLCG_02899 7.8e-174 yegQ O Peptidase U32
GPNPHLCG_02900 2.3e-119 yrrM 2.1.1.104 S O-methyltransferase
GPNPHLCG_02901 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GPNPHLCG_02902 1.2e-45 yrzB S Belongs to the UPF0473 family
GPNPHLCG_02903 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GPNPHLCG_02904 1.7e-41 yrzL S Belongs to the UPF0297 family
GPNPHLCG_02905 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GPNPHLCG_02906 2.5e-168 yrrI S AI-2E family transporter
GPNPHLCG_02907 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNPHLCG_02908 2.5e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
GPNPHLCG_02909 2.3e-108 gluC P ABC transporter
GPNPHLCG_02910 7.6e-107 glnP P ABC transporter
GPNPHLCG_02911 8e-08 S Protein of unknown function (DUF3918)
GPNPHLCG_02912 9.8e-31 yrzR
GPNPHLCG_02913 6.6e-81 yrrD S protein conserved in bacteria
GPNPHLCG_02914 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
GPNPHLCG_02915 1.4e-15 S COG0457 FOG TPR repeat
GPNPHLCG_02916 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
GPNPHLCG_02917 2e-211 iscS 2.8.1.7 E Cysteine desulfurase
GPNPHLCG_02918 1.2e-70 cymR K Transcriptional regulator
GPNPHLCG_02919 3.3e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
GPNPHLCG_02920 9e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
GPNPHLCG_02921 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GPNPHLCG_02922 4.8e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
GPNPHLCG_02924 1.1e-260 lytH 3.5.1.28 M COG3103 SH3 domain protein
GPNPHLCG_02925 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
GPNPHLCG_02926 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GPNPHLCG_02927 2.3e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GPNPHLCG_02928 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
GPNPHLCG_02929 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
GPNPHLCG_02930 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
GPNPHLCG_02931 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GPNPHLCG_02932 1.6e-48 yrzD S Post-transcriptional regulator
GPNPHLCG_02933 2.4e-268 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_02934 6.6e-111 yrbG S membrane
GPNPHLCG_02935 3.8e-73 yrzE S Protein of unknown function (DUF3792)
GPNPHLCG_02936 8e-39 yajC U Preprotein translocase subunit YajC
GPNPHLCG_02937 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
GPNPHLCG_02938 5.7e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GPNPHLCG_02939 2.6e-18 yrzS S Protein of unknown function (DUF2905)
GPNPHLCG_02940 1.9e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
GPNPHLCG_02941 4.5e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
GPNPHLCG_02942 1.1e-92 bofC S BofC C-terminal domain
GPNPHLCG_02943 1.5e-252 csbX EGP Major facilitator Superfamily
GPNPHLCG_02944 1.7e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
GPNPHLCG_02945 6.5e-119 yrzF T serine threonine protein kinase
GPNPHLCG_02947 1.3e-50 S Family of unknown function (DUF5412)
GPNPHLCG_02948 4.5e-261 alsT E Sodium alanine symporter
GPNPHLCG_02949 1e-125 yebC K transcriptional regulatory protein
GPNPHLCG_02950 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNPHLCG_02951 8.3e-157 safA M spore coat assembly protein SafA
GPNPHLCG_02952 1.4e-214 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GPNPHLCG_02953 7.3e-158 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
GPNPHLCG_02954 2e-302 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
GPNPHLCG_02955 4.1e-228 nifS 2.8.1.7 E Cysteine desulfurase
GPNPHLCG_02956 7.9e-94 niaR S small molecule binding protein (contains 3H domain)
GPNPHLCG_02957 7.6e-163 pheA 4.2.1.51 E Prephenate dehydratase
GPNPHLCG_02958 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
GPNPHLCG_02959 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GPNPHLCG_02960 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
GPNPHLCG_02961 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
GPNPHLCG_02962 4.1e-56 ysxB J ribosomal protein
GPNPHLCG_02963 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
GPNPHLCG_02964 9.2e-161 spoIVFB S Stage IV sporulation protein
GPNPHLCG_02965 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
GPNPHLCG_02966 4.7e-143 minD D Belongs to the ParA family
GPNPHLCG_02967 7.1e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
GPNPHLCG_02968 1.4e-84 mreD M shape-determining protein
GPNPHLCG_02969 1.1e-156 mreC M Involved in formation and maintenance of cell shape
GPNPHLCG_02970 1.8e-184 mreB D Rod shape-determining protein MreB
GPNPHLCG_02971 5.9e-126 radC E Belongs to the UPF0758 family
GPNPHLCG_02972 2.8e-102 maf D septum formation protein Maf
GPNPHLCG_02973 7.6e-167 spoIIB S Sporulation related domain
GPNPHLCG_02974 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
GPNPHLCG_02975 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
GPNPHLCG_02976 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
GPNPHLCG_02977 1.6e-25
GPNPHLCG_02978 1.7e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GPNPHLCG_02979 9.9e-199 spoVID M stage VI sporulation protein D
GPNPHLCG_02980 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
GPNPHLCG_02981 2.8e-182 hemB 4.2.1.24 H Belongs to the ALAD family
GPNPHLCG_02982 2.3e-142 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
GPNPHLCG_02983 4.3e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
GPNPHLCG_02984 3.6e-146 hemX O cytochrome C
GPNPHLCG_02985 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GPNPHLCG_02986 1.4e-89 ysxD
GPNPHLCG_02987 5.7e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
GPNPHLCG_02988 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GPNPHLCG_02989 2.8e-310 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
GPNPHLCG_02990 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GPNPHLCG_02991 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
GPNPHLCG_02992 1.9e-186 ysoA H Tetratricopeptide repeat
GPNPHLCG_02993 5.3e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNPHLCG_02994 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNPHLCG_02995 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GPNPHLCG_02996 4.2e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPNPHLCG_02997 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPNPHLCG_02998 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
GPNPHLCG_02999 0.0 ilvB 2.2.1.6 E Acetolactate synthase
GPNPHLCG_03001 9.2e-15 ysnE K acetyltransferase
GPNPHLCG_03002 3.7e-32 ysnE K acetyltransferase
GPNPHLCG_03003 4.9e-158 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GPNPHLCG_03004 1.2e-130 ysnF S protein conserved in bacteria
GPNPHLCG_03005 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_03006 1.4e-45 L transposase activity
GPNPHLCG_03008 5.3e-92 ysnB S Phosphoesterase
GPNPHLCG_03009 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPNPHLCG_03010 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPNPHLCG_03011 4.2e-195 gerM S COG5401 Spore germination protein
GPNPHLCG_03012 9.6e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPNPHLCG_03013 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_03014 1.8e-167 L Recombinase
GPNPHLCG_03015 7.7e-47 S YolD-like protein
GPNPHLCG_03018 2e-104 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
GPNPHLCG_03019 2.7e-31 xhlB S SPP1 phage holin
GPNPHLCG_03020 1.5e-27 xhlA S Haemolysin XhlA
GPNPHLCG_03021 1e-14 xkdX
GPNPHLCG_03023 6.9e-45 S Domain of unknown function (DUF2479)
GPNPHLCG_03024 1.3e-60
GPNPHLCG_03025 3e-106 Z012_12235 S homolog of phage Mu protein gp47
GPNPHLCG_03026 4.8e-23 S Protein of unknown function (DUF2634)
GPNPHLCG_03027 4.7e-23
GPNPHLCG_03028 3.6e-89
GPNPHLCG_03029 2.4e-30
GPNPHLCG_03030 3e-40 3.5.1.28 M LysM domain
GPNPHLCG_03031 5.7e-124 N phage tail tape measure protein
GPNPHLCG_03032 1.4e-15
GPNPHLCG_03033 3e-34
GPNPHLCG_03034 6.1e-103 Z012_02110 S Protein of unknown function (DUF3383)
GPNPHLCG_03035 7e-30
GPNPHLCG_03036 4e-23
GPNPHLCG_03037 3.6e-48
GPNPHLCG_03038 8.3e-17 S Phage gp6-like head-tail connector protein
GPNPHLCG_03039 5.9e-30 S Phage Mu protein F like protein
GPNPHLCG_03041 4.2e-111 S Phage capsid family
GPNPHLCG_03042 9.1e-64 S Domain of unknown function (DUF4355)
GPNPHLCG_03043 1.4e-158 S Phage portal protein, SPP1 Gp6-like
GPNPHLCG_03044 1.5e-185 ps334 S Terminase-like family
GPNPHLCG_03045 6.7e-75 yqaS L DNA packaging
GPNPHLCG_03048 6e-13 K Transcriptional regulator
GPNPHLCG_03050 5.2e-71 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
GPNPHLCG_03054 4.3e-76
GPNPHLCG_03056 2.3e-25 yqaO S Phage-like element PBSX protein XtrA
GPNPHLCG_03058 4e-54 S Protein of unknown function (DUF1064)
GPNPHLCG_03061 1.5e-120 xkdC L IstB-like ATP binding protein
GPNPHLCG_03062 2.3e-37 3.1.3.16 L DnaD domain protein
GPNPHLCG_03063 7.9e-117 recT L RecT family
GPNPHLCG_03064 2.9e-152 yqaJ L YqaJ-like viral recombinase domain
GPNPHLCG_03069 5.4e-69
GPNPHLCG_03070 5.3e-45 S DNA binding
GPNPHLCG_03072 1.2e-14 K Helix-turn-helix XRE-family like proteins
GPNPHLCG_03073 3.1e-23 K sequence-specific DNA binding
GPNPHLCG_03075 2.9e-20
GPNPHLCG_03076 1.2e-48 yqaB E IrrE N-terminal-like domain
GPNPHLCG_03077 1.2e-17 gerE K Transcriptional regulator
GPNPHLCG_03078 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
GPNPHLCG_03079 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNPHLCG_03080 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNPHLCG_03081 2.4e-107 sdhC C succinate dehydrogenase
GPNPHLCG_03082 1.2e-79 yslB S Protein of unknown function (DUF2507)
GPNPHLCG_03083 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPNPHLCG_03084 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPNPHLCG_03085 2e-52 trxA O Belongs to the thioredoxin family
GPNPHLCG_03086 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
GPNPHLCG_03088 1.8e-176 etfA C Electron transfer flavoprotein
GPNPHLCG_03089 4.5e-135 etfB C Electron transfer flavoprotein
GPNPHLCG_03090 1e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPNPHLCG_03091 2.3e-99 fadR K Transcriptional regulator
GPNPHLCG_03092 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNPHLCG_03093 7.3e-68 yshE S membrane
GPNPHLCG_03094 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNPHLCG_03095 0.0 polX L COG1796 DNA polymerase IV (family X)
GPNPHLCG_03096 1.7e-85 cvpA S membrane protein, required for colicin V production
GPNPHLCG_03097 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPNPHLCG_03098 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPNPHLCG_03099 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPNPHLCG_03100 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GPNPHLCG_03101 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GPNPHLCG_03102 2.6e-32 sspI S Belongs to the SspI family
GPNPHLCG_03103 3.5e-205 ysfB KT regulator
GPNPHLCG_03104 8e-263 glcD 1.1.3.15 C Glycolate oxidase subunit
GPNPHLCG_03105 2.1e-257 glcF C Glycolate oxidase
GPNPHLCG_03106 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
GPNPHLCG_03107 0.0 cstA T Carbon starvation protein
GPNPHLCG_03108 2.3e-300 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
GPNPHLCG_03109 2.9e-143 araQ G transport system permease
GPNPHLCG_03110 1.4e-167 araP G carbohydrate transport
GPNPHLCG_03111 1.7e-251 araN G carbohydrate transport
GPNPHLCG_03112 9.8e-222 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
GPNPHLCG_03113 2.3e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
GPNPHLCG_03114 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
GPNPHLCG_03115 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
GPNPHLCG_03116 1e-292 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
GPNPHLCG_03117 4e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNPHLCG_03118 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
GPNPHLCG_03119 9.2e-68 ysdB S Sigma-w pathway protein YsdB
GPNPHLCG_03120 7.5e-45 ysdA S Membrane
GPNPHLCG_03121 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GPNPHLCG_03122 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
GPNPHLCG_03123 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GPNPHLCG_03125 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GPNPHLCG_03126 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
GPNPHLCG_03127 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
GPNPHLCG_03128 0.0 lytS 2.7.13.3 T Histidine kinase
GPNPHLCG_03129 7.3e-149 ysaA S HAD-hyrolase-like
GPNPHLCG_03130 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPNPHLCG_03132 3e-156 ytxC S YtxC-like family
GPNPHLCG_03133 4.9e-111 ytxB S SNARE associated Golgi protein
GPNPHLCG_03134 3e-173 dnaI L Primosomal protein DnaI
GPNPHLCG_03135 8.5e-265 dnaB L Membrane attachment protein
GPNPHLCG_03136 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GPNPHLCG_03137 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
GPNPHLCG_03138 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPNPHLCG_03139 9.9e-67 ytcD K Transcriptional regulator
GPNPHLCG_03140 4.6e-203 ytbD EGP Major facilitator Superfamily
GPNPHLCG_03141 9.2e-158 ytbE S reductase
GPNPHLCG_03142 2.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GPNPHLCG_03143 2.5e-107 ytaF P Probably functions as a manganese efflux pump
GPNPHLCG_03144 2.1e-154 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
GPNPHLCG_03145 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GPNPHLCG_03146 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
GPNPHLCG_03147 1.8e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_03148 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
GPNPHLCG_03149 4.1e-242 icd 1.1.1.42 C isocitrate
GPNPHLCG_03150 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
GPNPHLCG_03151 4.7e-71 yeaL S membrane
GPNPHLCG_03152 3.4e-192 ytvI S sporulation integral membrane protein YtvI
GPNPHLCG_03153 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
GPNPHLCG_03154 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
GPNPHLCG_03155 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
GPNPHLCG_03156 5.6e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
GPNPHLCG_03157 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GPNPHLCG_03158 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
GPNPHLCG_03159 0.0 dnaE 2.7.7.7 L DNA polymerase
GPNPHLCG_03160 3.2e-56 ytrH S Sporulation protein YtrH
GPNPHLCG_03161 8.2e-69 ytrI
GPNPHLCG_03162 9.2e-29
GPNPHLCG_03163 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
GPNPHLCG_03164 2.4e-47 ytpI S YtpI-like protein
GPNPHLCG_03165 8e-241 ytoI K transcriptional regulator containing CBS domains
GPNPHLCG_03166 3.4e-158 ytnM S membrane transporter protein
GPNPHLCG_03167 6.6e-237 ytnL 3.5.1.47 E hydrolase activity
GPNPHLCG_03168 1.5e-126 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
GPNPHLCG_03169 7.5e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_03170 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
GPNPHLCG_03171 1.2e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_03172 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
GPNPHLCG_03173 6.4e-120 tcyM U Binding-protein-dependent transport system inner membrane component
GPNPHLCG_03174 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
GPNPHLCG_03175 1.3e-145 tcyK M Bacterial periplasmic substrate-binding proteins
GPNPHLCG_03176 2.1e-151 tcyK ET Bacterial periplasmic substrate-binding proteins
GPNPHLCG_03177 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
GPNPHLCG_03178 2.9e-173 ytlI K LysR substrate binding domain
GPNPHLCG_03179 1.7e-130 ytkL S Belongs to the UPF0173 family
GPNPHLCG_03180 4.2e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_03182 2.2e-265 argH 4.3.2.1 E argininosuccinate lyase
GPNPHLCG_03183 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
GPNPHLCG_03184 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
GPNPHLCG_03185 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GPNPHLCG_03186 7e-165 ytxK 2.1.1.72 L DNA methylase
GPNPHLCG_03187 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GPNPHLCG_03188 8.7e-70 ytfJ S Sporulation protein YtfJ
GPNPHLCG_03189 4.9e-112 ytfI S Protein of unknown function (DUF2953)
GPNPHLCG_03190 1.5e-86 yteJ S RDD family
GPNPHLCG_03191 1.1e-178 sppA OU signal peptide peptidase SppA
GPNPHLCG_03192 6.3e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GPNPHLCG_03193 0.0 ytcJ S amidohydrolase
GPNPHLCG_03194 2.9e-306 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPNPHLCG_03195 2e-29 sspB S spore protein
GPNPHLCG_03196 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GPNPHLCG_03197 1e-207 iscS2 2.8.1.7 E Cysteine desulfurase
GPNPHLCG_03198 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
GPNPHLCG_03199 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
GPNPHLCG_03200 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
GPNPHLCG_03201 1e-108 yttP K Transcriptional regulator
GPNPHLCG_03202 2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
GPNPHLCG_03203 2.2e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
GPNPHLCG_03204 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GPNPHLCG_03206 2e-236 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPNPHLCG_03207 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
GPNPHLCG_03208 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
GPNPHLCG_03209 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
GPNPHLCG_03210 1e-223 acuC BQ histone deacetylase
GPNPHLCG_03211 1.4e-125 motS N Flagellar motor protein
GPNPHLCG_03212 2.1e-146 motA N flagellar motor
GPNPHLCG_03213 3.8e-182 ccpA K catabolite control protein A
GPNPHLCG_03214 1.4e-195 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
GPNPHLCG_03215 1.7e-54 ytxJ O Protein of unknown function (DUF2847)
GPNPHLCG_03216 1.9e-16 ytxH S COG4980 Gas vesicle protein
GPNPHLCG_03217 2.8e-14 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
GPNPHLCG_03218 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
GPNPHLCG_03219 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
GPNPHLCG_03220 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPNPHLCG_03221 9.8e-149 ytpQ S Belongs to the UPF0354 family
GPNPHLCG_03222 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
GPNPHLCG_03223 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
GPNPHLCG_03224 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
GPNPHLCG_03225 1.1e-50 ytzB S small secreted protein
GPNPHLCG_03226 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
GPNPHLCG_03227 4.2e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
GPNPHLCG_03228 4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
GPNPHLCG_03229 2e-45 ytzH S YtzH-like protein
GPNPHLCG_03230 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
GPNPHLCG_03231 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
GPNPHLCG_03232 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
GPNPHLCG_03233 3.8e-165 ytlQ
GPNPHLCG_03234 1.2e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
GPNPHLCG_03235 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
GPNPHLCG_03236 3.9e-270 pepV 3.5.1.18 E Dipeptidase
GPNPHLCG_03237 2.1e-225 pbuO S permease
GPNPHLCG_03238 5.4e-201 ythQ U Bacterial ABC transporter protein EcsB
GPNPHLCG_03239 2.4e-130 ythP V ABC transporter
GPNPHLCG_03240 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
GPNPHLCG_03241 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_03242 1.4e-45 L transposase activity
GPNPHLCG_03243 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
GPNPHLCG_03244 1.5e-292 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_03245 8.2e-232 ytfP S HI0933-like protein
GPNPHLCG_03246 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
GPNPHLCG_03247 3.1e-26 yteV S Sporulation protein Cse60
GPNPHLCG_03248 3.4e-115 yteU S Integral membrane protein
GPNPHLCG_03249 2.5e-255 yteT S Oxidoreductase family, C-terminal alpha/beta domain
GPNPHLCG_03250 5.1e-72 yteS G transport
GPNPHLCG_03251 1.7e-220 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
GPNPHLCG_03252 2.2e-171 lplB G COG4209 ABC-type polysaccharide transport system, permease component
GPNPHLCG_03253 1.4e-163 ytdP K Transcriptional regulator
GPNPHLCG_03254 1.3e-221 ytdP K Transcriptional regulator
GPNPHLCG_03255 1.9e-286 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
GPNPHLCG_03256 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
GPNPHLCG_03257 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
GPNPHLCG_03258 2e-219 bioI 1.14.14.46 C Cytochrome P450
GPNPHLCG_03259 2.1e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
GPNPHLCG_03260 1.7e-125 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
GPNPHLCG_03261 9.7e-214 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
GPNPHLCG_03262 3.3e-258 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
GPNPHLCG_03263 5.5e-149 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
GPNPHLCG_03264 2.7e-171 ytaP S Acetyl xylan esterase (AXE1)
GPNPHLCG_03265 1.5e-189 msmR K Transcriptional regulator
GPNPHLCG_03266 4.4e-244 msmE G Bacterial extracellular solute-binding protein
GPNPHLCG_03267 6.2e-168 amyD P ABC transporter
GPNPHLCG_03268 2.8e-143 amyC P ABC transporter (permease)
GPNPHLCG_03269 1.2e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
GPNPHLCG_03270 2.1e-51 ytwF P Sulfurtransferase
GPNPHLCG_03271 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
GPNPHLCG_03272 7.7e-55 ytvB S Protein of unknown function (DUF4257)
GPNPHLCG_03273 3.9e-142 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
GPNPHLCG_03274 1.3e-210 yttB EGP Major facilitator Superfamily
GPNPHLCG_03275 3.5e-33 yttA 2.7.13.3 S Pfam Transposase IS66
GPNPHLCG_03276 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_03277 3.6e-308 bceB V ABC transporter (permease)
GPNPHLCG_03278 3.3e-138 bceA V ABC transporter, ATP-binding protein
GPNPHLCG_03279 6e-177 T PhoQ Sensor
GPNPHLCG_03280 2.9e-128 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_03281 1.6e-233 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
GPNPHLCG_03282 9.1e-127 ytrE V ABC transporter, ATP-binding protein
GPNPHLCG_03283 2.5e-146
GPNPHLCG_03284 3e-152 P ABC-2 family transporter protein
GPNPHLCG_03285 4.2e-161 ytrB P abc transporter atp-binding protein
GPNPHLCG_03286 5.1e-66 ytrA K GntR family transcriptional regulator
GPNPHLCG_03288 1.5e-40 ytzC S Protein of unknown function (DUF2524)
GPNPHLCG_03289 8.1e-190 yhcC S Fe-S oxidoreductase
GPNPHLCG_03290 7.4e-106 ytqB J Putative rRNA methylase
GPNPHLCG_03291 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
GPNPHLCG_03292 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
GPNPHLCG_03293 2.7e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GPNPHLCG_03294 1.7e-254 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_03295 0.0 asnB 6.3.5.4 E Asparagine synthase
GPNPHLCG_03296 1.4e-223 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GPNPHLCG_03297 6.3e-309 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GPNPHLCG_03298 6.6e-37 ytmB S Protein of unknown function (DUF2584)
GPNPHLCG_03299 8.8e-147 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
GPNPHLCG_03300 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
GPNPHLCG_03301 1.4e-144 ytlC P ABC transporter
GPNPHLCG_03302 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
GPNPHLCG_03303 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
GPNPHLCG_03304 5.4e-63 ytkC S Bacteriophage holin family
GPNPHLCG_03305 2.1e-76 dps P Belongs to the Dps family
GPNPHLCG_03307 3.1e-72 ytkA S YtkA-like
GPNPHLCG_03308 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
GPNPHLCG_03309 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GPNPHLCG_03310 3.6e-41 rpmE2 J Ribosomal protein L31
GPNPHLCG_03311 2.3e-248 cydA 1.10.3.14 C oxidase, subunit
GPNPHLCG_03312 1.1e-187 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
GPNPHLCG_03313 4.3e-24 S Domain of Unknown Function (DUF1540)
GPNPHLCG_03314 2.6e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
GPNPHLCG_03315 1.8e-229 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
GPNPHLCG_03316 4.5e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
GPNPHLCG_03317 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
GPNPHLCG_03318 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
GPNPHLCG_03319 2.8e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
GPNPHLCG_03320 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GPNPHLCG_03321 2.8e-151 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
GPNPHLCG_03322 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GPNPHLCG_03323 2.7e-271 menF 5.4.4.2 HQ Isochorismate synthase
GPNPHLCG_03324 7.4e-132 dksA T COG1734 DnaK suppressor protein
GPNPHLCG_03325 3.3e-152 galU 2.7.7.9 M Nucleotidyl transferase
GPNPHLCG_03326 5.8e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNPHLCG_03327 3.4e-177 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
GPNPHLCG_03328 1.8e-226 ytcC M Glycosyltransferase Family 4
GPNPHLCG_03330 2.8e-204 cotS S Seems to be required for the assembly of the CotSA protein in spores
GPNPHLCG_03331 7.2e-214 cotSA M Glycosyl transferases group 1
GPNPHLCG_03332 1.1e-203 cotI S Spore coat protein
GPNPHLCG_03333 9.9e-77 tspO T membrane
GPNPHLCG_03334 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
GPNPHLCG_03335 1.7e-284 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
GPNPHLCG_03336 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
GPNPHLCG_03337 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
GPNPHLCG_03338 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GPNPHLCG_03347 7.8e-08
GPNPHLCG_03348 1.3e-09
GPNPHLCG_03355 2e-08
GPNPHLCG_03360 3.4e-39 S COG NOG14552 non supervised orthologous group
GPNPHLCG_03361 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
GPNPHLCG_03362 2.1e-91 M1-753 M FR47-like protein
GPNPHLCG_03363 1.2e-187 yuaG 3.4.21.72 S protein conserved in bacteria
GPNPHLCG_03364 1.9e-76 yuaF OU Membrane protein implicated in regulation of membrane protease activity
GPNPHLCG_03365 3.3e-83 yuaE S DinB superfamily
GPNPHLCG_03366 9.6e-106 yuaD
GPNPHLCG_03367 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
GPNPHLCG_03368 2.3e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
GPNPHLCG_03369 5.5e-95 yuaC K Belongs to the GbsR family
GPNPHLCG_03370 2.2e-91 yuaB
GPNPHLCG_03371 1.5e-134 L Integrase core domain
GPNPHLCG_03372 6e-44 tnpIS3 L Transposase
GPNPHLCG_03373 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
GPNPHLCG_03374 1.6e-236 ktrB P Potassium
GPNPHLCG_03375 1e-38 yiaA S yiaA/B two helix domain
GPNPHLCG_03376 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPNPHLCG_03377 2.2e-274 yubD P Major Facilitator Superfamily
GPNPHLCG_03378 2.2e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
GPNPHLCG_03380 7.8e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
GPNPHLCG_03381 1.3e-194 yubA S transporter activity
GPNPHLCG_03382 9.7e-183 ygjR S Oxidoreductase
GPNPHLCG_03383 1.1e-252 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
GPNPHLCG_03384 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
GPNPHLCG_03385 1.8e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
GPNPHLCG_03386 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
GPNPHLCG_03387 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
GPNPHLCG_03388 7.3e-238 mcpA NT chemotaxis protein
GPNPHLCG_03389 8.5e-295 mcpA NT chemotaxis protein
GPNPHLCG_03390 7.9e-42 mcpA NT chemotaxis protein
GPNPHLCG_03391 2e-164 mcpA NT chemotaxis protein
GPNPHLCG_03392 1.9e-222 mcpA NT chemotaxis protein
GPNPHLCG_03393 9.3e-138 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
GPNPHLCG_03394 1e-35
GPNPHLCG_03395 2.1e-72 yugU S Uncharacterised protein family UPF0047
GPNPHLCG_03396 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
GPNPHLCG_03397 4.6e-233 yugS S COG1253 Hemolysins and related proteins containing CBS domains
GPNPHLCG_03398 1.4e-116 yugP S Zn-dependent protease
GPNPHLCG_03399 2.3e-38
GPNPHLCG_03400 1.1e-53 mstX S Membrane-integrating protein Mistic
GPNPHLCG_03401 8.2e-182 yugO P COG1226 Kef-type K transport systems
GPNPHLCG_03402 1.4e-71 yugN S YugN-like family
GPNPHLCG_03404 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
GPNPHLCG_03405 2.8e-229 yugK C Dehydrogenase
GPNPHLCG_03406 2e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
GPNPHLCG_03407 1.1e-34 yuzA S Domain of unknown function (DUF378)
GPNPHLCG_03408 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
GPNPHLCG_03409 2.1e-199 yugH 2.6.1.1 E Aminotransferase
GPNPHLCG_03410 1.6e-85 alaR K Transcriptional regulator
GPNPHLCG_03411 1.4e-155 yugF I Hydrolase
GPNPHLCG_03412 1.3e-38 yugE S Domain of unknown function (DUF1871)
GPNPHLCG_03413 5.4e-225 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
GPNPHLCG_03414 4.6e-233 T PhoQ Sensor
GPNPHLCG_03415 2.2e-69 kapB G Kinase associated protein B
GPNPHLCG_03416 4.2e-115 kapD L the KinA pathway to sporulation
GPNPHLCG_03418 4.2e-184 yuxJ EGP Major facilitator Superfamily
GPNPHLCG_03419 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
GPNPHLCG_03420 1.8e-74 yuxK S protein conserved in bacteria
GPNPHLCG_03421 1.8e-77 yufK S Family of unknown function (DUF5366)
GPNPHLCG_03422 1.3e-293 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
GPNPHLCG_03423 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
GPNPHLCG_03424 1.7e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
GPNPHLCG_03425 9.2e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
GPNPHLCG_03426 1.2e-183 yufP S Belongs to the binding-protein-dependent transport system permease family
GPNPHLCG_03427 6.6e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
GPNPHLCG_03428 3.7e-233 maeN C COG3493 Na citrate symporter
GPNPHLCG_03429 3.2e-14
GPNPHLCG_03430 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
GPNPHLCG_03431 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNPHLCG_03432 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNPHLCG_03433 9.3e-262 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNPHLCG_03434 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNPHLCG_03435 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
GPNPHLCG_03436 3.3e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
GPNPHLCG_03437 1.8e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
GPNPHLCG_03438 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_03439 0.0 comP 2.7.13.3 T Histidine kinase
GPNPHLCG_03441 1.3e-147 comQ H Polyprenyl synthetase
GPNPHLCG_03443 1.1e-22 yuzC
GPNPHLCG_03444 4.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
GPNPHLCG_03445 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GPNPHLCG_03446 1.5e-103 pncA Q COG1335 Amidases related to nicotinamidase
GPNPHLCG_03447 1e-66 yueI S Protein of unknown function (DUF1694)
GPNPHLCG_03448 7.4e-39 yueH S YueH-like protein
GPNPHLCG_03449 2.5e-30 yueG S Spore germination protein gerPA/gerPF
GPNPHLCG_03450 1.9e-184 yueF S transporter activity
GPNPHLCG_03451 5.2e-71 S Protein of unknown function (DUF2283)
GPNPHLCG_03452 1.1e-95 yueE S phosphohydrolase
GPNPHLCG_03453 9.2e-130 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_03454 6.6e-65 yueC S Family of unknown function (DUF5383)
GPNPHLCG_03455 0.0 esaA S type VII secretion protein EsaA
GPNPHLCG_03456 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
GPNPHLCG_03457 6.4e-209 essB S WXG100 protein secretion system (Wss), protein YukC
GPNPHLCG_03458 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
GPNPHLCG_03459 2.8e-45 esxA S Belongs to the WXG100 family
GPNPHLCG_03460 2.8e-227 yukF QT Transcriptional regulator
GPNPHLCG_03461 2.6e-203 ald 1.4.1.1 E Belongs to the AlaDH PNT family
GPNPHLCG_03462 4.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
GPNPHLCG_03463 4.2e-35 mbtH S MbtH-like protein
GPNPHLCG_03464 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_03465 1e-173 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
GPNPHLCG_03466 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
GPNPHLCG_03467 1.5e-222 entC 5.4.4.2 HQ Isochorismate synthase
GPNPHLCG_03468 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03469 2.5e-166 besA S Putative esterase
GPNPHLCG_03470 8.3e-121 yuiH S Oxidoreductase molybdopterin binding domain
GPNPHLCG_03471 4.4e-93 bioY S Biotin biosynthesis protein
GPNPHLCG_03472 3.9e-211 yuiF S antiporter
GPNPHLCG_03473 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GPNPHLCG_03474 2e-77 yuiD S protein conserved in bacteria
GPNPHLCG_03475 4e-116 yuiC S protein conserved in bacteria
GPNPHLCG_03476 8.4e-27 yuiB S Putative membrane protein
GPNPHLCG_03477 5.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
GPNPHLCG_03478 1.7e-187 yumC 1.18.1.2, 1.19.1.1 C reductase
GPNPHLCG_03480 1.6e-157 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
GPNPHLCG_03481 6.1e-114 paiB K Putative FMN-binding domain
GPNPHLCG_03482 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_03483 3.7e-63 erpA S Belongs to the HesB IscA family
GPNPHLCG_03484 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GPNPHLCG_03485 1.7e-197 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPNPHLCG_03486 3.2e-39 yuzB S Belongs to the UPF0349 family
GPNPHLCG_03487 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
GPNPHLCG_03488 1.1e-55 yuzD S protein conserved in bacteria
GPNPHLCG_03489 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
GPNPHLCG_03490 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
GPNPHLCG_03491 2.8e-171 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
GPNPHLCG_03492 5.2e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GPNPHLCG_03493 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
GPNPHLCG_03494 8.5e-198 yutH S Spore coat protein
GPNPHLCG_03495 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPNPHLCG_03496 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
GPNPHLCG_03497 1e-75 yutE S Protein of unknown function DUF86
GPNPHLCG_03498 9.7e-48 yutD S protein conserved in bacteria
GPNPHLCG_03499 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
GPNPHLCG_03500 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GPNPHLCG_03501 1.3e-195 lytH M Peptidase, M23
GPNPHLCG_03502 9.3e-133 yunB S Sporulation protein YunB (Spo_YunB)
GPNPHLCG_03503 1.1e-47 yunC S Domain of unknown function (DUF1805)
GPNPHLCG_03504 5.1e-262 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
GPNPHLCG_03505 1.3e-140 yunE S membrane transporter protein
GPNPHLCG_03506 1.1e-169 yunF S Protein of unknown function DUF72
GPNPHLCG_03507 6.7e-62 yunG
GPNPHLCG_03508 2.5e-258 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
GPNPHLCG_03509 2.7e-299 pucR QT COG2508 Regulator of polyketide synthase expression
GPNPHLCG_03510 3.9e-235 pbuX F Permease family
GPNPHLCG_03511 4.3e-223 pbuX F xanthine
GPNPHLCG_03512 2.4e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
GPNPHLCG_03513 2.7e-55 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
GPNPHLCG_03514 4e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
GPNPHLCG_03515 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
GPNPHLCG_03516 1.4e-150 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
GPNPHLCG_03517 9e-110 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
GPNPHLCG_03518 3.2e-186 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GPNPHLCG_03519 1.7e-237 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
GPNPHLCG_03520 3.4e-233 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
GPNPHLCG_03521 3.8e-167 bsn L Ribonuclease
GPNPHLCG_03522 1e-24 S branched-chain amino acid
GPNPHLCG_03523 9.3e-74 azlC E AzlC protein
GPNPHLCG_03524 1.2e-157 gntR9 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
GPNPHLCG_03525 8.8e-36 L COG3666 Transposase and inactivated derivatives
GPNPHLCG_03526 9.5e-67 L COG3666 Transposase and inactivated derivatives
GPNPHLCG_03527 4.1e-42 S B3/4 domain
GPNPHLCG_03528 1.8e-170 2.5.1.48, 4.4.1.1, 4.4.1.11, 4.4.1.2, 4.4.1.8 E methionine gamma-lyase
GPNPHLCG_03529 1.3e-22 I Fatty acid desaturase
GPNPHLCG_03530 9e-80 I Fatty acid desaturase
GPNPHLCG_03532 1.5e-195 msmX P Belongs to the ABC transporter superfamily
GPNPHLCG_03533 2.1e-134 yurK K UTRA
GPNPHLCG_03534 1.1e-148 yurL 2.7.1.218 G pfkB family carbohydrate kinase
GPNPHLCG_03535 1.2e-238 yurO G COG1653 ABC-type sugar transport system, periplasmic component
GPNPHLCG_03536 3.7e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
GPNPHLCG_03537 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
GPNPHLCG_03538 2.2e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
GPNPHLCG_03540 1e-41
GPNPHLCG_03541 1.4e-45 L transposase activity
GPNPHLCG_03542 2.3e-108 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_03543 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_03544 1e-270 sufB O FeS cluster assembly
GPNPHLCG_03545 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
GPNPHLCG_03546 7.9e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GPNPHLCG_03547 9.1e-245 sufD O assembly protein SufD
GPNPHLCG_03548 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
GPNPHLCG_03549 5.6e-46 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GPNPHLCG_03550 6.1e-146 metQ P Belongs to the NlpA lipoprotein family
GPNPHLCG_03551 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
GPNPHLCG_03552 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GPNPHLCG_03553 3.2e-56 yusD S SCP-2 sterol transfer family
GPNPHLCG_03554 5.6e-55 traF CO Thioredoxin
GPNPHLCG_03555 2.1e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
GPNPHLCG_03556 1.1e-39 yusG S Protein of unknown function (DUF2553)
GPNPHLCG_03557 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
GPNPHLCG_03558 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
GPNPHLCG_03559 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
GPNPHLCG_03560 1.4e-215 fadA 2.3.1.16 I Belongs to the thiolase family
GPNPHLCG_03561 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
GPNPHLCG_03562 8.1e-09 S YuzL-like protein
GPNPHLCG_03563 3.9e-162 fadM E Proline dehydrogenase
GPNPHLCG_03564 5.1e-40
GPNPHLCG_03565 5.4e-53 yusN M Coat F domain
GPNPHLCG_03566 4.6e-74 yusO K Iron dependent repressor, N-terminal DNA binding domain
GPNPHLCG_03567 8.5e-293 yusP P Major facilitator superfamily
GPNPHLCG_03568 7.1e-65 yusQ S Tautomerase enzyme
GPNPHLCG_03569 2.2e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03570 5.7e-158 yusT K LysR substrate binding domain
GPNPHLCG_03571 5.6e-39 yusU S Protein of unknown function (DUF2573)
GPNPHLCG_03572 1e-153 yusV 3.6.3.34 HP ABC transporter
GPNPHLCG_03573 3.3e-66 S YusW-like protein
GPNPHLCG_03574 1.2e-300 pepF2 E COG1164 Oligoendopeptidase F
GPNPHLCG_03575 3.2e-150 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03576 1.2e-79 dps P Ferritin-like domain
GPNPHLCG_03577 4.4e-234 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNPHLCG_03578 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_03579 9.7e-250 cssS 2.7.13.3 T PhoQ Sensor
GPNPHLCG_03580 4.8e-157 yuxN K Transcriptional regulator
GPNPHLCG_03581 2.8e-260 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
GPNPHLCG_03582 8.6e-24 S Protein of unknown function (DUF3970)
GPNPHLCG_03583 5.9e-245 gerAA EG Spore germination protein
GPNPHLCG_03584 3.8e-196 gerAB E Spore germination protein
GPNPHLCG_03585 1.4e-177 gerAC S Spore germination B3/ GerAC like, C-terminal
GPNPHLCG_03586 8.1e-106 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_03587 1.6e-186 vraS 2.7.13.3 T Histidine kinase
GPNPHLCG_03588 9.5e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
GPNPHLCG_03589 3.1e-116 liaG S Putative adhesin
GPNPHLCG_03590 3.6e-104 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
GPNPHLCG_03591 7.3e-62 liaI S membrane
GPNPHLCG_03592 5.9e-225 yvqJ EGP Major facilitator Superfamily
GPNPHLCG_03593 1.6e-100 yvqK 2.5.1.17 S Adenosyltransferase
GPNPHLCG_03594 5.4e-245 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
GPNPHLCG_03595 8.5e-185 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_03596 2.6e-169 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
GPNPHLCG_03597 1.3e-137 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03598 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
GPNPHLCG_03599 0.0 T PhoQ Sensor
GPNPHLCG_03600 8.1e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_03601 3.6e-22
GPNPHLCG_03602 4e-96 yvrI K RNA polymerase
GPNPHLCG_03603 6.9e-19 S YvrJ protein family
GPNPHLCG_03604 6.8e-228 oxdC 4.1.1.2 G Oxalate decarboxylase
GPNPHLCG_03605 2.5e-63 yvrL S Regulatory protein YrvL
GPNPHLCG_03606 2.6e-209 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
GPNPHLCG_03607 1.6e-123 macB V ABC transporter, ATP-binding protein
GPNPHLCG_03608 1.3e-173 M Efflux transporter rnd family, mfp subunit
GPNPHLCG_03609 1.3e-148 fhuC 3.6.3.34 HP ABC transporter
GPNPHLCG_03610 4.9e-174 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_03611 1.8e-179 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GPNPHLCG_03612 4.5e-177 fhuD P ABC transporter
GPNPHLCG_03613 4.9e-236 yvsH E Arginine ornithine antiporter
GPNPHLCG_03614 6.5e-16 S Small spore protein J (Spore_SspJ)
GPNPHLCG_03615 1.7e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
GPNPHLCG_03616 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
GPNPHLCG_03617 1.1e-167 yvgK P COG1910 Periplasmic molybdate-binding protein domain
GPNPHLCG_03618 1.2e-135 modA P COG0725 ABC-type molybdate transport system, periplasmic component
GPNPHLCG_03619 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
GPNPHLCG_03620 1.1e-155 yvgN S reductase
GPNPHLCG_03621 5.4e-86 yvgO
GPNPHLCG_03622 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
GPNPHLCG_03623 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
GPNPHLCG_03624 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GPNPHLCG_03625 0.0 helD 3.6.4.12 L DNA helicase
GPNPHLCG_03626 4.1e-107 yvgT S membrane
GPNPHLCG_03627 8.5e-72 bdbC O Required for disulfide bond formation in some proteins
GPNPHLCG_03628 2.7e-104 bdbD O Thioredoxin
GPNPHLCG_03629 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
GPNPHLCG_03630 0.0 copA 3.6.3.54 P P-type ATPase
GPNPHLCG_03631 5.9e-29 copZ P Copper resistance protein CopZ
GPNPHLCG_03632 2.2e-48 csoR S transcriptional
GPNPHLCG_03633 6.4e-193 yvaA 1.1.1.371 S Oxidoreductase
GPNPHLCG_03634 1.6e-117 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GPNPHLCG_03635 1e-105 yvaC S Fusaric acid resistance protein-like
GPNPHLCG_03636 7.9e-217 yvaC S Fusaric acid resistance protein-like
GPNPHLCG_03637 5.7e-73 yvaD S Family of unknown function (DUF5360)
GPNPHLCG_03638 6.9e-54 yvaE P Small Multidrug Resistance protein
GPNPHLCG_03639 3.1e-96 K Bacterial regulatory proteins, tetR family
GPNPHLCG_03640 4.2e-87 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03641 2.2e-14 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_03642 8.2e-12
GPNPHLCG_03643 1.2e-183 A Pre-toxin TG
GPNPHLCG_03644 3.5e-32
GPNPHLCG_03646 3.3e-119 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
GPNPHLCG_03647 3.2e-58 S Bacteriophage holin family
GPNPHLCG_03649 3.5e-08
GPNPHLCG_03650 8.6e-64
GPNPHLCG_03653 2.2e-58
GPNPHLCG_03654 1.6e-246 NU Prophage endopeptidase tail
GPNPHLCG_03655 9.6e-115 S Phage tail protein
GPNPHLCG_03656 0.0 S peptidoglycan catabolic process
GPNPHLCG_03657 4.8e-10
GPNPHLCG_03658 1.2e-26
GPNPHLCG_03659 2e-61
GPNPHLCG_03660 3.3e-30
GPNPHLCG_03661 9.4e-49 S Bacteriophage HK97-gp10, putative tail-component
GPNPHLCG_03662 8e-37 S Phage head-tail joining protein
GPNPHLCG_03663 1e-26 S peptidoglycan catabolic process
GPNPHLCG_03665 6.5e-181 S capsid protein
GPNPHLCG_03666 1.8e-105 S peptidase activity
GPNPHLCG_03667 2.1e-214 S Phage portal protein
GPNPHLCG_03668 6.4e-10
GPNPHLCG_03669 1.2e-220 S Phage Terminase
GPNPHLCG_03670 4.6e-70 S Phage terminase, small subunit
GPNPHLCG_03671 2.1e-20
GPNPHLCG_03672 3.8e-63 S HNH endonuclease
GPNPHLCG_03675 8.3e-60 L Phage integrase family
GPNPHLCG_03676 4e-51 wecC 1.1.1.336 M ArpU family transcriptional regulator
GPNPHLCG_03679 5.2e-88
GPNPHLCG_03682 1.6e-07 yqaO S Phage-like element PBSX protein XtrA
GPNPHLCG_03686 2.1e-30
GPNPHLCG_03687 7e-41 dnaC L IstB-like ATP binding protein
GPNPHLCG_03688 1.9e-89 ybl78 L Conserved phage C-terminus (Phg_2220_C)
GPNPHLCG_03690 5.6e-10 S sequence-specific DNA binding
GPNPHLCG_03692 2.1e-43 K Helix-turn-helix XRE-family like proteins
GPNPHLCG_03695 1.2e-59
GPNPHLCG_03696 2.4e-123 S Phage integrase family
GPNPHLCG_03698 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GPNPHLCG_03699 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
GPNPHLCG_03700 4.8e-142 est 3.1.1.1 S Carboxylesterase
GPNPHLCG_03701 2.4e-23 secG U Preprotein translocase subunit SecG
GPNPHLCG_03702 1.5e-151 yvaM S Serine aminopeptidase, S33
GPNPHLCG_03703 9.8e-36 yvzC K Transcriptional
GPNPHLCG_03704 2.6e-68 K transcriptional
GPNPHLCG_03705 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
GPNPHLCG_03706 2.2e-54 yodB K transcriptional
GPNPHLCG_03707 1.2e-19 NT chemotaxis protein
GPNPHLCG_03708 2.2e-170 NT chemotaxis protein
GPNPHLCG_03709 1.5e-110 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNPHLCG_03710 4.2e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPNPHLCG_03711 1.6e-109 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNPHLCG_03712 9.2e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPNPHLCG_03713 7.4e-60 yvbF K Belongs to the GbsR family
GPNPHLCG_03714 7.9e-13 S Sporulation delaying protein SdpA
GPNPHLCG_03715 4.9e-171
GPNPHLCG_03716 4.4e-08
GPNPHLCG_03717 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
GPNPHLCG_03718 4.5e-45 sdpR K transcriptional
GPNPHLCG_03719 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNPHLCG_03720 3.6e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
GPNPHLCG_03721 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
GPNPHLCG_03722 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
GPNPHLCG_03723 3.5e-97 yvbF K Belongs to the GbsR family
GPNPHLCG_03724 6e-101 yvbG U UPF0056 membrane protein
GPNPHLCG_03725 1.9e-112 yvbH S YvbH-like oligomerisation region
GPNPHLCG_03726 2.2e-120 exoY M Membrane
GPNPHLCG_03727 8.1e-252 tcaA S response to antibiotic
GPNPHLCG_03728 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
GPNPHLCG_03729 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
GPNPHLCG_03730 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
GPNPHLCG_03731 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
GPNPHLCG_03732 8.5e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
GPNPHLCG_03733 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
GPNPHLCG_03734 9.1e-184 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPNPHLCG_03735 1.6e-252 araE EGP Major facilitator Superfamily
GPNPHLCG_03736 5.5e-203 araR K transcriptional
GPNPHLCG_03737 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_03738 3.3e-158 yvbU K Transcriptional regulator
GPNPHLCG_03739 1.2e-155 yvbV EG EamA-like transporter family
GPNPHLCG_03740 6.2e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
GPNPHLCG_03741 8.9e-195 yvbX S Glycosyl hydrolase
GPNPHLCG_03742 1.2e-132 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPNPHLCG_03743 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
GPNPHLCG_03744 4.2e-135 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
GPNPHLCG_03745 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_03746 2.1e-197 desK 2.7.13.3 T Histidine kinase
GPNPHLCG_03747 7.6e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
GPNPHLCG_03748 8.9e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
GPNPHLCG_03749 3.7e-156 rsbQ S Alpha/beta hydrolase family
GPNPHLCG_03750 7.2e-196 rsbU 3.1.3.3 T response regulator
GPNPHLCG_03751 1.9e-250 galA 3.2.1.89 G arabinogalactan
GPNPHLCG_03752 0.0 lacA 3.2.1.23 G beta-galactosidase
GPNPHLCG_03753 7.2e-150 ganQ P transport
GPNPHLCG_03754 6.5e-232 malC P COG1175 ABC-type sugar transport systems, permease components
GPNPHLCG_03755 3e-229 cycB G COG2182 Maltose-binding periplasmic proteins domains
GPNPHLCG_03756 2e-183 lacR K Transcriptional regulator
GPNPHLCG_03757 2.3e-112 yvfI K COG2186 Transcriptional regulators
GPNPHLCG_03758 3.7e-307 yvfH C L-lactate permease
GPNPHLCG_03759 7.2e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
GPNPHLCG_03760 1e-31 yvfG S YvfG protein
GPNPHLCG_03761 2.4e-186 yvfF GM Exopolysaccharide biosynthesis protein
GPNPHLCG_03762 4e-220 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
GPNPHLCG_03763 1e-55 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
GPNPHLCG_03764 1.1e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GPNPHLCG_03765 7.5e-259 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_03766 3.6e-196 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNPHLCG_03767 3.1e-206 epsI GM pyruvyl transferase
GPNPHLCG_03768 4.1e-192 epsH GT2 S Glycosyltransferase like family 2
GPNPHLCG_03769 1.8e-206 epsG S EpsG family
GPNPHLCG_03770 1.9e-217 epsF GT4 M Glycosyl transferases group 1
GPNPHLCG_03771 1.2e-154 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
GPNPHLCG_03772 1.3e-218 epsD GT4 M Glycosyl transferase 4-like
GPNPHLCG_03773 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
GPNPHLCG_03774 2.3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
GPNPHLCG_03775 4e-122 ywqC M biosynthesis protein
GPNPHLCG_03776 6.3e-76 slr K transcriptional
GPNPHLCG_03777 2.5e-283 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
GPNPHLCG_03779 5.1e-92 padC Q Phenolic acid decarboxylase
GPNPHLCG_03780 7.6e-74 MA20_18690 S Protein of unknown function (DUF3237)
GPNPHLCG_03781 1.1e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
GPNPHLCG_03782 5e-262 pbpE V Beta-lactamase
GPNPHLCG_03783 3.5e-274 sacB 2.4.1.10 GH68 M levansucrase activity
GPNPHLCG_03784 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
GPNPHLCG_03785 1.8e-295 yveA E amino acid
GPNPHLCG_03786 7.4e-106 yvdT K Transcriptional regulator
GPNPHLCG_03787 1.5e-50 ykkC P Small Multidrug Resistance protein
GPNPHLCG_03788 7.1e-50 sugE P Small Multidrug Resistance protein
GPNPHLCG_03789 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
GPNPHLCG_03791 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
GPNPHLCG_03792 5e-114 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
GPNPHLCG_03793 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
GPNPHLCG_03794 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
GPNPHLCG_03795 5e-154 malA S Protein of unknown function (DUF1189)
GPNPHLCG_03796 9.5e-147 malD P transport
GPNPHLCG_03797 4.5e-244 malC P COG1175 ABC-type sugar transport systems, permease components
GPNPHLCG_03798 2.4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
GPNPHLCG_03799 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
GPNPHLCG_03800 3.3e-172 yvdE K Transcriptional regulator
GPNPHLCG_03801 5.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
GPNPHLCG_03802 5.9e-29 yvdC S MazG nucleotide pyrophosphohydrolase domain
GPNPHLCG_03803 2.8e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
GPNPHLCG_03804 4.8e-105 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
GPNPHLCG_03805 7.3e-183 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GPNPHLCG_03806 0.0 yxdM V ABC transporter (permease)
GPNPHLCG_03807 5.6e-141 yvcR V ABC transporter, ATP-binding protein
GPNPHLCG_03808 1.3e-196 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
GPNPHLCG_03809 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_03810 1.9e-141 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
GPNPHLCG_03811 1.6e-36 crh G Phosphocarrier protein Chr
GPNPHLCG_03812 4.1e-170 whiA K May be required for sporulation
GPNPHLCG_03813 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
GPNPHLCG_03814 5.7e-166 rapZ S Displays ATPase and GTPase activities
GPNPHLCG_03815 3.9e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPNPHLCG_03816 5.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
GPNPHLCG_03817 1.1e-97 usp CBM50 M protein conserved in bacteria
GPNPHLCG_03818 4.5e-277 S COG0457 FOG TPR repeat
GPNPHLCG_03819 0.0 msbA2 3.6.3.44 V ABC transporter
GPNPHLCG_03821 0.0
GPNPHLCG_03822 1.6e-118
GPNPHLCG_03823 8.8e-113 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
GPNPHLCG_03824 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
GPNPHLCG_03825 1.1e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GPNPHLCG_03826 1.1e-115 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GPNPHLCG_03827 1.8e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
GPNPHLCG_03828 3.2e-226 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GPNPHLCG_03829 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
GPNPHLCG_03830 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
GPNPHLCG_03831 2.3e-139 yvpB NU protein conserved in bacteria
GPNPHLCG_03832 9.3e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
GPNPHLCG_03833 1.6e-80 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
GPNPHLCG_03834 3.2e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
GPNPHLCG_03835 3.4e-161 yvoD P COG0370 Fe2 transport system protein B
GPNPHLCG_03836 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GPNPHLCG_03837 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
GPNPHLCG_03838 5.4e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
GPNPHLCG_03839 2.3e-128 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
GPNPHLCG_03840 2.1e-123 yvoA K transcriptional
GPNPHLCG_03841 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
GPNPHLCG_03842 1.2e-50 yvlD S Membrane
GPNPHLCG_03843 2.6e-26 pspB KT PspC domain
GPNPHLCG_03844 9.2e-166 yvlB S Putative adhesin
GPNPHLCG_03845 8e-49 yvlA
GPNPHLCG_03846 5.7e-33 yvkN
GPNPHLCG_03847 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPNPHLCG_03848 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
GPNPHLCG_03849 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
GPNPHLCG_03850 1.2e-30 csbA S protein conserved in bacteria
GPNPHLCG_03851 0.0 yvkC 2.7.9.2 GT Phosphotransferase
GPNPHLCG_03852 7e-101 yvkB K Transcriptional regulator
GPNPHLCG_03853 7.9e-228 yvkA EGP Major facilitator Superfamily
GPNPHLCG_03854 1.9e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNPHLCG_03855 1.8e-72 swrA S Swarming motility protein
GPNPHLCG_03856 2e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
GPNPHLCG_03857 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
GPNPHLCG_03858 1.6e-123 ftsE D cell division ATP-binding protein FtsE
GPNPHLCG_03859 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
GPNPHLCG_03860 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
GPNPHLCG_03861 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GPNPHLCG_03862 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
GPNPHLCG_03863 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GPNPHLCG_03864 4.6e-51
GPNPHLCG_03865 1.9e-08 fliT S bacterial-type flagellum organization
GPNPHLCG_03866 1.9e-68 fliS N flagellar protein FliS
GPNPHLCG_03867 7.7e-248 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
GPNPHLCG_03868 1.2e-52 flaG N flagellar protein FlaG
GPNPHLCG_03869 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
GPNPHLCG_03870 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
GPNPHLCG_03871 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
GPNPHLCG_03872 2.6e-50 yviE
GPNPHLCG_03873 1.4e-156 flgL N Belongs to the bacterial flagellin family
GPNPHLCG_03874 5.9e-264 flgK N flagellar hook-associated protein
GPNPHLCG_03875 9.2e-78 flgN NOU FlgN protein
GPNPHLCG_03876 1.6e-39 flgM KNU Negative regulator of flagellin synthesis
GPNPHLCG_03877 4.6e-73 yvyF S flagellar protein
GPNPHLCG_03878 1.3e-128 comFC S Phosphoribosyl transferase domain
GPNPHLCG_03879 5.7e-46 comFB S Late competence development protein ComFB
GPNPHLCG_03880 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
GPNPHLCG_03881 7.3e-155 degV S protein conserved in bacteria
GPNPHLCG_03882 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
GPNPHLCG_03883 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
GPNPHLCG_03884 5.9e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
GPNPHLCG_03885 6e-163 yvhJ K Transcriptional regulator
GPNPHLCG_03886 5.8e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
GPNPHLCG_03887 1.3e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
GPNPHLCG_03888 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
GPNPHLCG_03889 3.9e-114 tuaF M protein involved in exopolysaccharide biosynthesis
GPNPHLCG_03890 4.8e-252 tuaE M Teichuronic acid biosynthesis protein
GPNPHLCG_03891 2e-258 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNPHLCG_03892 3.2e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
GPNPHLCG_03893 4.4e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
GPNPHLCG_03894 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
GPNPHLCG_03895 3.3e-94 M Glycosyltransferase like family 2
GPNPHLCG_03896 2e-208 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
GPNPHLCG_03897 0.0 lytB 3.5.1.28 D Stage II sporulation protein
GPNPHLCG_03898 1e-11
GPNPHLCG_03899 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
GPNPHLCG_03900 6.5e-215 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
GPNPHLCG_03901 2.7e-88 M Glycosyltransferase like family 2
GPNPHLCG_03902 1.6e-99 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPNPHLCG_03903 9.1e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
GPNPHLCG_03904 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
GPNPHLCG_03905 3.9e-266 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
GPNPHLCG_03906 1e-132 tagG GM Transport permease protein
GPNPHLCG_03907 2.6e-89
GPNPHLCG_03908 2.7e-55
GPNPHLCG_03909 4.8e-208 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GPNPHLCG_03910 1.1e-88 ggaA M Glycosyltransferase like family 2
GPNPHLCG_03911 3.3e-145 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPNPHLCG_03912 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
GPNPHLCG_03913 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
GPNPHLCG_03914 1.5e-105 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GPNPHLCG_03915 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
GPNPHLCG_03916 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
GPNPHLCG_03917 5.7e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GPNPHLCG_03918 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
GPNPHLCG_03919 2.6e-214 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
GPNPHLCG_03920 4.3e-188 pmi 5.3.1.8 G mannose-6-phosphate isomerase
GPNPHLCG_03921 5.3e-262 gerBA EG Spore germination protein
GPNPHLCG_03922 1.3e-191 gerBB E Spore germination protein
GPNPHLCG_03923 1.4e-206 gerAC S Spore germination protein
GPNPHLCG_03924 3.9e-246 ywtG EGP Major facilitator Superfamily
GPNPHLCG_03925 1.4e-170 ywtF K Transcriptional regulator
GPNPHLCG_03926 1.6e-160 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
GPNPHLCG_03927 1.5e-134 L Integrase core domain
GPNPHLCG_03928 6e-44 tnpIS3 L Transposase
GPNPHLCG_03929 4.9e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
GPNPHLCG_03930 3.6e-21 ywtC
GPNPHLCG_03931 1.8e-217 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
GPNPHLCG_03932 8.6e-70 pgsC S biosynthesis protein
GPNPHLCG_03933 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
GPNPHLCG_03934 3e-176 rbsR K transcriptional
GPNPHLCG_03935 1.3e-157 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GPNPHLCG_03936 2.6e-62 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
GPNPHLCG_03937 2.8e-274 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
GPNPHLCG_03938 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
GPNPHLCG_03939 3.1e-159 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
GPNPHLCG_03940 1.2e-91 batE T Sh3 type 3 domain protein
GPNPHLCG_03941 8e-48 ywsA S Protein of unknown function (DUF3892)
GPNPHLCG_03942 6.3e-96 ywrO S NADPH-quinone reductase (modulator of drug activity B)
GPNPHLCG_03943 4.9e-201 L COG3666 Transposase and inactivated derivatives
GPNPHLCG_03944 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
GPNPHLCG_03945 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
GPNPHLCG_03946 1.1e-169 alsR K LysR substrate binding domain
GPNPHLCG_03947 2.3e-139 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GPNPHLCG_03948 4.7e-52 ywrJ
GPNPHLCG_03949 1.1e-22 cotB
GPNPHLCG_03950 1.1e-206 cotH M Spore Coat
GPNPHLCG_03951 1.1e-12
GPNPHLCG_03952 4.4e-109 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GPNPHLCG_03953 2.7e-52 S Domain of unknown function (DUF4181)
GPNPHLCG_03954 9.7e-302 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
GPNPHLCG_03955 8e-82 ywrC K Transcriptional regulator
GPNPHLCG_03956 3.5e-103 ywrB P Chromate transporter
GPNPHLCG_03957 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
GPNPHLCG_03959 3.3e-100 ywqN S NAD(P)H-dependent
GPNPHLCG_03960 4.2e-161 K Transcriptional regulator
GPNPHLCG_03961 8.2e-123 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
GPNPHLCG_03962 1.9e-52
GPNPHLCG_03964 4.3e-51
GPNPHLCG_03965 6.4e-76
GPNPHLCG_03966 1.7e-239 ywqJ S Pre-toxin TG
GPNPHLCG_03967 6.9e-38 ywqI S Family of unknown function (DUF5344)
GPNPHLCG_03968 1e-19 S Domain of unknown function (DUF5082)
GPNPHLCG_03969 7.8e-151 ywqG S Domain of unknown function (DUF1963)
GPNPHLCG_03970 6e-44 tnpIS3 L Transposase
GPNPHLCG_03971 1.5e-134 L Integrase core domain
GPNPHLCG_03972 7e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GPNPHLCG_03973 1.9e-138 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
GPNPHLCG_03974 5.8e-118 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
GPNPHLCG_03975 2e-116 ywqC M biosynthesis protein
GPNPHLCG_03976 1.2e-17
GPNPHLCG_03977 7.8e-307 ywqB S SWIM zinc finger
GPNPHLCG_03978 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
GPNPHLCG_03979 2.6e-155 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
GPNPHLCG_03980 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
GPNPHLCG_03981 2.2e-57 ssbB L Single-stranded DNA-binding protein
GPNPHLCG_03982 1.2e-29 ywpG
GPNPHLCG_03983 1.1e-66 ywpF S YwpF-like protein
GPNPHLCG_03984 1.2e-238 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_03985 5.4e-49 srtA 3.4.22.70 M Sortase family
GPNPHLCG_03986 3.2e-153 ywpD T Histidine kinase
GPNPHLCG_03987 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
GPNPHLCG_03988 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
GPNPHLCG_03989 4.8e-196 S aspartate phosphatase
GPNPHLCG_03990 2.6e-141 flhP N flagellar basal body
GPNPHLCG_03991 6.9e-126 flhO N flagellar basal body
GPNPHLCG_03992 3.5e-180 mbl D Rod shape-determining protein
GPNPHLCG_03993 3e-44 spoIIID K Stage III sporulation protein D
GPNPHLCG_03994 2.1e-70 ywoH K COG1846 Transcriptional regulators
GPNPHLCG_03995 2.7e-211 ywoG EGP Major facilitator Superfamily
GPNPHLCG_03996 8.8e-230 ywoF P Right handed beta helix region
GPNPHLCG_03997 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
GPNPHLCG_03998 9.8e-242 ywoD EGP Major facilitator superfamily
GPNPHLCG_03999 6.8e-104 phzA Q Isochorismatase family
GPNPHLCG_04000 1.7e-76
GPNPHLCG_04001 1.3e-224 amt P Ammonium transporter
GPNPHLCG_04002 1.6e-58 nrgB K Belongs to the P(II) protein family
GPNPHLCG_04003 6.5e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
GPNPHLCG_04004 6.7e-123 2.1.1.72 L DNA methylase
GPNPHLCG_04005 1.4e-18 K Helix-turn-helix XRE-family like proteins
GPNPHLCG_04006 3.6e-32 L Restriction endonuclease BamHI
GPNPHLCG_04007 5.3e-116 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
GPNPHLCG_04008 3.2e-89 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
GPNPHLCG_04009 1.1e-07 ywnC S Family of unknown function (DUF5362)
GPNPHLCG_04010 2.9e-70 ywnF S Family of unknown function (DUF5392)
GPNPHLCG_04011 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPNPHLCG_04012 4.5e-143 mta K transcriptional
GPNPHLCG_04013 1.7e-58 ywnC S Family of unknown function (DUF5362)
GPNPHLCG_04014 6.7e-108 ywnB S NAD(P)H-binding
GPNPHLCG_04015 1.7e-64 ywnA K Transcriptional regulator
GPNPHLCG_04016 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
GPNPHLCG_04017 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
GPNPHLCG_04018 1.8e-50 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
GPNPHLCG_04020 1.4e-10 csbD K CsbD-like
GPNPHLCG_04021 1.1e-83 ywmF S Peptidase M50
GPNPHLCG_04022 2.7e-104 S response regulator aspartate phosphatase
GPNPHLCG_04023 2e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GPNPHLCG_04024 1.3e-145 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GPNPHLCG_04026 6.1e-120 ywmD S protein containing a von Willebrand factor type A (vWA) domain
GPNPHLCG_04027 3.3e-121 ywmC S protein containing a von Willebrand factor type A (vWA) domain
GPNPHLCG_04028 7.5e-178 spoIID D Stage II sporulation protein D
GPNPHLCG_04029 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPNPHLCG_04030 9e-133 ywmB S TATA-box binding
GPNPHLCG_04031 1.3e-32 ywzB S membrane
GPNPHLCG_04032 1.4e-86 ywmA
GPNPHLCG_04033 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
GPNPHLCG_04034 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GPNPHLCG_04035 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GPNPHLCG_04036 4.5e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GPNPHLCG_04037 1.5e-87 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPNPHLCG_04038 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GPNPHLCG_04039 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GPNPHLCG_04040 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
GPNPHLCG_04041 2.5e-62 atpI S ATP synthase
GPNPHLCG_04042 1e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GPNPHLCG_04043 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GPNPHLCG_04044 1.6e-94 ywlG S Belongs to the UPF0340 family
GPNPHLCG_04045 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
GPNPHLCG_04046 1.9e-77 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GPNPHLCG_04047 4.9e-91 mntP P Probably functions as a manganese efflux pump
GPNPHLCG_04048 2e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
GPNPHLCG_04049 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
GPNPHLCG_04050 6.1e-112 spoIIR S stage II sporulation protein R
GPNPHLCG_04051 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
GPNPHLCG_04053 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
GPNPHLCG_04054 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GPNPHLCG_04055 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNPHLCG_04056 1.2e-89 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
GPNPHLCG_04057 8.6e-160 ywkB S Membrane transport protein
GPNPHLCG_04058 0.0 sfcA 1.1.1.38 C malic enzyme
GPNPHLCG_04059 1.6e-103 tdk 2.7.1.21 F thymidine kinase
GPNPHLCG_04060 1.1e-32 rpmE J Binds the 23S rRNA
GPNPHLCG_04061 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
GPNPHLCG_04062 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
GPNPHLCG_04063 3.3e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GPNPHLCG_04064 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GPNPHLCG_04065 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
GPNPHLCG_04066 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
GPNPHLCG_04067 1.3e-90 ywjG S Domain of unknown function (DUF2529)
GPNPHLCG_04068 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
GPNPHLCG_04069 1.4e-47 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
GPNPHLCG_04070 3.1e-209 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
GPNPHLCG_04071 0.0 fadF C COG0247 Fe-S oxidoreductase
GPNPHLCG_04072 3.2e-220 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
GPNPHLCG_04073 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
GPNPHLCG_04074 2.7e-42 ywjC
GPNPHLCG_04075 5.9e-94 ywjB H RibD C-terminal domain
GPNPHLCG_04076 0.0 ywjA V ABC transporter
GPNPHLCG_04077 2.1e-285 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GPNPHLCG_04078 3.1e-124 narI 1.7.5.1 C nitrate reductase, gamma
GPNPHLCG_04079 1.1e-93 narJ 1.7.5.1 C nitrate reductase
GPNPHLCG_04080 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
GPNPHLCG_04081 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNPHLCG_04082 7e-86 arfM T cyclic nucleotide binding
GPNPHLCG_04083 1.7e-139 ywiC S YwiC-like protein
GPNPHLCG_04084 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
GPNPHLCG_04085 1e-213 narK P COG2223 Nitrate nitrite transporter
GPNPHLCG_04086 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
GPNPHLCG_04087 4.7e-73 ywiB S protein conserved in bacteria
GPNPHLCG_04088 1e-07 S Bacteriocin subtilosin A
GPNPHLCG_04089 1.4e-269 C Fe-S oxidoreductases
GPNPHLCG_04091 3.3e-132 cbiO V ABC transporter
GPNPHLCG_04092 4.2e-234 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
GPNPHLCG_04093 7.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
GPNPHLCG_04094 3.3e-247 L Peptidase, M16
GPNPHLCG_04096 2.5e-245 ywhL CO amine dehydrogenase activity
GPNPHLCG_04097 8e-204 ywhK CO amine dehydrogenase activity
GPNPHLCG_04098 7.5e-86 S aspartate phosphatase
GPNPHLCG_04100 1.2e-49 ywhH S Aminoacyl-tRNA editing domain
GPNPHLCG_04101 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
GPNPHLCG_04102 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
GPNPHLCG_04103 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
GPNPHLCG_04104 3.6e-49
GPNPHLCG_04105 5.2e-95 ywhD S YwhD family
GPNPHLCG_04106 3.3e-118 ywhC S Peptidase family M50
GPNPHLCG_04107 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
GPNPHLCG_04108 3.3e-71 ywhA K Transcriptional regulator
GPNPHLCG_04109 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GPNPHLCG_04111 1e-233 mmr U Major Facilitator Superfamily
GPNPHLCG_04112 6.2e-79 yffB K Transcriptional regulator
GPNPHLCG_04113 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
GPNPHLCG_04114 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
GPNPHLCG_04115 3.1e-36 ywzC S Belongs to the UPF0741 family
GPNPHLCG_04116 5.1e-110 rsfA_1
GPNPHLCG_04117 9.1e-156 ywfM EG EamA-like transporter family
GPNPHLCG_04118 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
GPNPHLCG_04119 1.1e-156 cysL K Transcriptional regulator
GPNPHLCG_04120 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
GPNPHLCG_04121 3.3e-146 ywfI C May function as heme-dependent peroxidase
GPNPHLCG_04122 2.2e-137 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_04123 1.5e-233 ywfG 2.6.1.83 E Aminotransferase class I and II
GPNPHLCG_04124 7.3e-209 bacE EGP Major facilitator Superfamily
GPNPHLCG_04125 5.2e-270 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
GPNPHLCG_04126 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
GPNPHLCG_04127 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
GPNPHLCG_04128 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
GPNPHLCG_04129 6e-206 ywfA EGP Major facilitator Superfamily
GPNPHLCG_04130 5.7e-261 lysP E amino acid
GPNPHLCG_04131 5.2e-118 rocB E arginine degradation protein
GPNPHLCG_04132 9.8e-158 rocB E arginine degradation protein
GPNPHLCG_04133 3.5e-296 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
GPNPHLCG_04134 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
GPNPHLCG_04135 1.2e-77
GPNPHLCG_04136 1.3e-86 spsL 5.1.3.13 M Spore Coat
GPNPHLCG_04137 1e-159 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
GPNPHLCG_04138 3e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
GPNPHLCG_04139 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GPNPHLCG_04140 3.7e-185 spsG M Spore Coat
GPNPHLCG_04141 5.3e-130 spsF M Spore Coat
GPNPHLCG_04142 3.5e-213 spsE 2.5.1.56 M acid synthase
GPNPHLCG_04143 1.7e-162 spsD 2.3.1.210 K Spore Coat
GPNPHLCG_04144 1e-223 spsC E Belongs to the DegT DnrJ EryC1 family
GPNPHLCG_04145 2.7e-274 spsB M Capsule polysaccharide biosynthesis protein
GPNPHLCG_04146 1.8e-144 spsA M Spore Coat
GPNPHLCG_04147 9e-74 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
GPNPHLCG_04148 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_04149 1.4e-45 L transposase activity
GPNPHLCG_04150 4.3e-59 ywdK S small membrane protein
GPNPHLCG_04151 2.4e-237 ywdJ F Xanthine uracil
GPNPHLCG_04152 5e-48 ywdI S Family of unknown function (DUF5327)
GPNPHLCG_04153 2.1e-260 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPNPHLCG_04154 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GPNPHLCG_04155 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
GPNPHLCG_04157 4e-113 ywdD
GPNPHLCG_04158 1.3e-57 pex K Transcriptional regulator PadR-like family
GPNPHLCG_04159 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
GPNPHLCG_04160 2e-28 ywdA
GPNPHLCG_04161 8.1e-287 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
GPNPHLCG_04162 1.5e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_04163 5.7e-138 focA P Formate/nitrite transporter
GPNPHLCG_04164 1.2e-149 sacT K transcriptional antiterminator
GPNPHLCG_04166 0.0 vpr O Belongs to the peptidase S8 family
GPNPHLCG_04167 9.5e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_04168 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
GPNPHLCG_04169 8.6e-202 rodA D Belongs to the SEDS family
GPNPHLCG_04170 5e-38 ywcE S Required for proper spore morphogenesis. Important for spore germination
GPNPHLCG_04171 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPNPHLCG_04172 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
GPNPHLCG_04173 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GPNPHLCG_04174 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
GPNPHLCG_04175 1e-35 ywzA S membrane
GPNPHLCG_04176 3.3e-302 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
GPNPHLCG_04177 4e-228 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GPNPHLCG_04178 9.5e-60 gtcA S GtrA-like protein
GPNPHLCG_04179 4.7e-120 ywcC K transcriptional regulator
GPNPHLCG_04181 6.4e-48 ywcB S Protein of unknown function, DUF485
GPNPHLCG_04182 6.9e-49 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_04183 2.8e-197 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GPNPHLCG_04184 4e-110 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
GPNPHLCG_04185 3.2e-223 ywbN P Dyp-type peroxidase family protein
GPNPHLCG_04186 2e-163 ycdO P periplasmic lipoprotein involved in iron transport
GPNPHLCG_04187 3.8e-252 P COG0672 High-affinity Fe2 Pb2 permease
GPNPHLCG_04188 9.4e-113 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
GPNPHLCG_04189 3.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
GPNPHLCG_04190 4.3e-153 ywbI K Transcriptional regulator
GPNPHLCG_04191 1.9e-57 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
GPNPHLCG_04192 2.6e-110 ywbG M effector of murein hydrolase
GPNPHLCG_04193 9e-207 ywbF EGP Major facilitator Superfamily
GPNPHLCG_04194 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
GPNPHLCG_04195 2.3e-218 ywbD 2.1.1.191 J Methyltransferase
GPNPHLCG_04196 4.4e-67 ywbC 4.4.1.5 E glyoxalase
GPNPHLCG_04197 2.3e-122 ywbB S Protein of unknown function (DUF2711)
GPNPHLCG_04198 1.4e-240 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNPHLCG_04199 3.5e-269 epr 3.4.21.62 O Belongs to the peptidase S8 family
GPNPHLCG_04200 2.9e-241 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_04201 4e-153 sacY K transcriptional antiterminator
GPNPHLCG_04202 1.3e-167 gspA M General stress
GPNPHLCG_04203 4.6e-126 ywaF S Integral membrane protein
GPNPHLCG_04204 8.1e-88 ywaE K Transcriptional regulator
GPNPHLCG_04205 1.3e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GPNPHLCG_04206 6.8e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
GPNPHLCG_04207 5.3e-92 K Helix-turn-helix XRE-family like proteins
GPNPHLCG_04208 4.2e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
GPNPHLCG_04209 1e-130 ynfM EGP Major facilitator Superfamily
GPNPHLCG_04210 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
GPNPHLCG_04211 6e-44 tnpIS3 L Transposase
GPNPHLCG_04212 1.5e-134 L Integrase core domain
GPNPHLCG_04213 1.5e-164 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
GPNPHLCG_04214 5.7e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_04215 2.7e-232 dltB M membrane protein involved in D-alanine export
GPNPHLCG_04216 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
GPNPHLCG_04217 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
GPNPHLCG_04218 6.2e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_04219 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
GPNPHLCG_04220 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
GPNPHLCG_04221 5.6e-37 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
GPNPHLCG_04222 7e-248 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
GPNPHLCG_04223 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
GPNPHLCG_04224 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
GPNPHLCG_04225 1.1e-19 yxzF
GPNPHLCG_04226 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
GPNPHLCG_04227 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
GPNPHLCG_04228 2.6e-44 yxlH EGP Major facilitator Superfamily
GPNPHLCG_04229 2.9e-157 yxlH EGP Major facilitator Superfamily
GPNPHLCG_04230 4e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
GPNPHLCG_04231 7e-164 yxlF V ABC transporter, ATP-binding protein
GPNPHLCG_04232 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
GPNPHLCG_04233 1.4e-30
GPNPHLCG_04234 3.9e-48 yxlC S Family of unknown function (DUF5345)
GPNPHLCG_04235 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
GPNPHLCG_04236 1.9e-253 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
GPNPHLCG_04237 4.8e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GPNPHLCG_04238 0.0 cydD V ATP-binding protein
GPNPHLCG_04239 1.2e-310 cydD V ATP-binding
GPNPHLCG_04240 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
GPNPHLCG_04241 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
GPNPHLCG_04242 2.1e-228 cimH C COG3493 Na citrate symporter
GPNPHLCG_04243 1.4e-309 3.4.24.84 O Peptidase family M48
GPNPHLCG_04245 1.6e-154 yxkH G Polysaccharide deacetylase
GPNPHLCG_04246 5.9e-205 msmK P Belongs to the ABC transporter superfamily
GPNPHLCG_04247 1.2e-163 lrp QT PucR C-terminal helix-turn-helix domain
GPNPHLCG_04248 7.4e-272 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNPHLCG_04249 7.3e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
GPNPHLCG_04250 1.4e-73 yxkC S Domain of unknown function (DUF4352)
GPNPHLCG_04251 5.7e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
GPNPHLCG_04252 3.4e-77 S Protein of unknown function (DUF1453)
GPNPHLCG_04253 2.1e-174 yxjM T Signal transduction histidine kinase
GPNPHLCG_04254 9.8e-115 K helix_turn_helix, Lux Regulon
GPNPHLCG_04255 3e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
GPNPHLCG_04257 1.4e-86 yxjI S LURP-one-related
GPNPHLCG_04258 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
GPNPHLCG_04259 1e-220 yxjG 2.1.1.14 E Methionine synthase
GPNPHLCG_04260 2.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
GPNPHLCG_04261 3.4e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPNPHLCG_04262 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPNPHLCG_04263 5.9e-250 yxjC EG COG2610 H gluconate symporter and related permeases
GPNPHLCG_04264 2.1e-157 rlmA 2.1.1.187 Q Methyltransferase domain
GPNPHLCG_04265 1.2e-211 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPNPHLCG_04266 4.4e-102 T Domain of unknown function (DUF4163)
GPNPHLCG_04267 3e-47 yxiS
GPNPHLCG_04268 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
GPNPHLCG_04269 6.6e-224 citH C Citrate transporter
GPNPHLCG_04270 3.3e-143 exoK GH16 M licheninase activity
GPNPHLCG_04271 8.8e-139 licT K transcriptional antiterminator
GPNPHLCG_04272 4e-111
GPNPHLCG_04273 6.8e-229 yxiO S COG2270 Permeases of the major facilitator superfamily
GPNPHLCG_04274 2.8e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
GPNPHLCG_04275 4.7e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_04276 7.8e-55 padR K Transcriptional regulator PadR-like family
GPNPHLCG_04277 6.5e-61 S Protein of unknown function (DUF2812)
GPNPHLCG_04280 1.3e-42 yxiJ S YxiJ-like protein
GPNPHLCG_04283 1.2e-34
GPNPHLCG_04284 1.1e-83 yxiI S Protein of unknown function (DUF2716)
GPNPHLCG_04285 1.5e-136
GPNPHLCG_04286 8.3e-13 yxiG
GPNPHLCG_04287 7.6e-16 yxiG
GPNPHLCG_04288 1.9e-38 S Protein of unknown function (DUF2750)
GPNPHLCG_04289 3.4e-52 yxxG
GPNPHLCG_04290 4.3e-68 yxiG
GPNPHLCG_04291 4.1e-44
GPNPHLCG_04292 4.9e-76
GPNPHLCG_04293 4.7e-94 S Protein of unknown function (DUF4240)
GPNPHLCG_04294 4.5e-141
GPNPHLCG_04296 7e-55
GPNPHLCG_04297 6.1e-80 wapA M COG3209 Rhs family protein
GPNPHLCG_04298 4.1e-14 yxiJ S YxiJ-like protein
GPNPHLCG_04299 0.0 wapA M COG3209 Rhs family protein
GPNPHLCG_04300 2e-161 yxxF EG EamA-like transporter family
GPNPHLCG_04301 7e-72 yxiE T Belongs to the universal stress protein A family
GPNPHLCG_04302 4.8e-279 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNPHLCG_04303 1.3e-310 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
GPNPHLCG_04304 5.5e-53
GPNPHLCG_04305 1.1e-210 S nuclease activity
GPNPHLCG_04306 1.4e-38 yxiC S Family of unknown function (DUF5344)
GPNPHLCG_04307 4.6e-21 S Domain of unknown function (DUF5082)
GPNPHLCG_04308 0.0 L HKD family nuclease
GPNPHLCG_04309 3.5e-59 nudG 3.6.1.55, 3.6.1.65 L COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
GPNPHLCG_04310 3.6e-166 L Protein of unknown function (DUF2726)
GPNPHLCG_04311 8.8e-242 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
GPNPHLCG_04312 8.5e-265 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GPNPHLCG_04313 9.1e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
GPNPHLCG_04314 9e-117 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
GPNPHLCG_04315 3.6e-233 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
GPNPHLCG_04316 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GPNPHLCG_04317 2e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GPNPHLCG_04318 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
GPNPHLCG_04319 6.8e-104 yxxB S Domain of Unknown Function (DUF1206)
GPNPHLCG_04320 4.5e-32 yxxB S Domain of Unknown Function (DUF1206)
GPNPHLCG_04321 6.4e-199 eutH E Ethanolamine utilisation protein, EutH
GPNPHLCG_04322 1.9e-250 yxeQ S MmgE/PrpD family
GPNPHLCG_04323 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
GPNPHLCG_04324 1.2e-132 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
GPNPHLCG_04325 2.7e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
GPNPHLCG_04326 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
GPNPHLCG_04327 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
GPNPHLCG_04328 6.3e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GPNPHLCG_04329 5.9e-188 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
GPNPHLCG_04330 9.2e-147 yidA S hydrolases of the HAD superfamily
GPNPHLCG_04333 1.3e-20 yxeE
GPNPHLCG_04334 1.9e-16 yxeD
GPNPHLCG_04335 7.2e-68
GPNPHLCG_04336 2.3e-176 fhuD P ABC transporter
GPNPHLCG_04337 1.5e-58 yxeA S Protein of unknown function (DUF1093)
GPNPHLCG_04338 6.9e-306 yxdM V ABC transporter (permease)
GPNPHLCG_04339 3.4e-68 yxdL V ABC transporter, ATP-binding protein
GPNPHLCG_04340 1.3e-51 yxdL V ABC transporter, ATP-binding protein
GPNPHLCG_04341 7.6e-180 T PhoQ Sensor
GPNPHLCG_04342 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_04343 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
GPNPHLCG_04344 3.3e-147 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
GPNPHLCG_04345 8.6e-167 iolH G Xylose isomerase-like TIM barrel
GPNPHLCG_04346 6.8e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
GPNPHLCG_04347 2e-124 iolF EGP Major facilitator Superfamily
GPNPHLCG_04348 5.9e-81 iolF EGP Major facilitator Superfamily
GPNPHLCG_04349 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
GPNPHLCG_04350 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
GPNPHLCG_04351 2.5e-178 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
GPNPHLCG_04352 1e-153 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
GPNPHLCG_04353 2.6e-280 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
GPNPHLCG_04354 9.5e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
GPNPHLCG_04355 8.3e-176 iolS C Aldo keto reductase
GPNPHLCG_04356 1.1e-41
GPNPHLCG_04358 1.3e-12 S CGNR zinc finger
GPNPHLCG_04359 3.4e-78 T HPP family
GPNPHLCG_04360 8.3e-31 csbC EGP Major facilitator Superfamily
GPNPHLCG_04361 1.2e-183 csbC EGP Major facilitator Superfamily
GPNPHLCG_04362 0.0 htpG O Molecular chaperone. Has ATPase activity
GPNPHLCG_04364 1.7e-17 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_04365 3e-122 IQ Enoyl-(Acyl carrier protein) reductase
GPNPHLCG_04366 1.1e-206 yxbF K Bacterial regulatory proteins, tetR family
GPNPHLCG_04367 7.6e-247 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
GPNPHLCG_04368 4e-12 yxaI S membrane protein domain
GPNPHLCG_04369 1.6e-78 S PQQ-like domain
GPNPHLCG_04370 2.3e-64 S Family of unknown function (DUF5391)
GPNPHLCG_04371 8.4e-73 yxaI S membrane protein domain
GPNPHLCG_04372 1.2e-227 P Protein of unknown function (DUF418)
GPNPHLCG_04373 7.1e-197 yxaG 1.13.11.24 S AraC-like ligand binding domain
GPNPHLCG_04374 3.5e-100 yxaF K Transcriptional regulator
GPNPHLCG_04375 1.2e-199 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
GPNPHLCG_04376 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_04377 1.4e-45 L transposase activity
GPNPHLCG_04378 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_04379 5.2e-50 S LrgA family
GPNPHLCG_04380 2.6e-118 yxaC M effector of murein hydrolase
GPNPHLCG_04381 3.7e-193 yxaB GM Polysaccharide pyruvyl transferase
GPNPHLCG_04382 9.5e-206 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
GPNPHLCG_04383 7.3e-127 gntR K transcriptional
GPNPHLCG_04384 3.9e-303 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
GPNPHLCG_04385 2.9e-230 gntP EG COG2610 H gluconate symporter and related permeases
GPNPHLCG_04386 6.1e-271 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GPNPHLCG_04387 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
GPNPHLCG_04388 6.1e-285 ahpF O Alkyl hydroperoxide reductase
GPNPHLCG_04389 7e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
GPNPHLCG_04390 9.1e-20 2.7.1.199 G phosphoenolpyruvate-dependent sugar phosphotransferase system
GPNPHLCG_04391 5.1e-125 yydK K Transcriptional regulator
GPNPHLCG_04392 7.6e-13
GPNPHLCG_04393 8e-118 S ABC-2 family transporter protein
GPNPHLCG_04394 2.9e-108 prrC P ABC transporter
GPNPHLCG_04395 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
GPNPHLCG_04398 7.4e-283 L ATPase involved in DNA repair
GPNPHLCG_04399 3.6e-08
GPNPHLCG_04400 8.1e-235 T Putative serine esterase (DUF676)
GPNPHLCG_04401 8.9e-88
GPNPHLCG_04402 1.2e-64
GPNPHLCG_04403 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GPNPHLCG_04404 1.1e-09 S YyzF-like protein
GPNPHLCG_04405 8.8e-31
GPNPHLCG_04406 6.7e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
GPNPHLCG_04408 8.2e-30 yycQ S Protein of unknown function (DUF2651)
GPNPHLCG_04409 3.9e-207 yycP
GPNPHLCG_04410 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GPNPHLCG_04411 1.9e-83 yycN 2.3.1.128 K Acetyltransferase
GPNPHLCG_04412 1.5e-187 S aspartate phosphatase
GPNPHLCG_04414 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
GPNPHLCG_04415 2.8e-260 rocE E amino acid
GPNPHLCG_04416 2.6e-233 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
GPNPHLCG_04417 3.4e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
GPNPHLCG_04418 1.1e-171 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
GPNPHLCG_04419 3.4e-94 K PFAM response regulator receiver
GPNPHLCG_04420 1.8e-74 S Peptidase propeptide and YPEB domain
GPNPHLCG_04421 3.2e-33 S Peptidase propeptide and YPEB domain
GPNPHLCG_04422 3.3e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GPNPHLCG_04423 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
GPNPHLCG_04424 1.6e-154 yycI S protein conserved in bacteria
GPNPHLCG_04425 1.3e-257 yycH S protein conserved in bacteria
GPNPHLCG_04426 0.0 vicK 2.7.13.3 T Histidine kinase
GPNPHLCG_04427 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
GPNPHLCG_04432 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GPNPHLCG_04433 1.6e-54 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNPHLCG_04434 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
GPNPHLCG_04435 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
GPNPHLCG_04437 1.9e-15 yycC K YycC-like protein
GPNPHLCG_04438 2.1e-219 yeaN P COG2807 Cyanate permease
GPNPHLCG_04439 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GPNPHLCG_04440 2.2e-73 rplI J binds to the 23S rRNA
GPNPHLCG_04441 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
GPNPHLCG_04442 8.3e-160 yybS S membrane
GPNPHLCG_04444 4e-14 cotF M Spore coat protein
GPNPHLCG_04445 1.7e-51 cotF M Spore coat protein
GPNPHLCG_04446 6.8e-68 ydeP3 K Transcriptional regulator
GPNPHLCG_04447 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
GPNPHLCG_04448 1.5e-58
GPNPHLCG_04450 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
GPNPHLCG_04451 4.3e-111 K TipAS antibiotic-recognition domain
GPNPHLCG_04452 5.8e-122
GPNPHLCG_04453 8.6e-66 yybH S SnoaL-like domain
GPNPHLCG_04454 6.9e-121 yybG S Pentapeptide repeat-containing protein
GPNPHLCG_04455 2e-214 ynfM EGP Major facilitator Superfamily
GPNPHLCG_04456 2.6e-163 yybE K Transcriptional regulator
GPNPHLCG_04457 1.4e-77 yjcF S Acetyltransferase (GNAT) domain
GPNPHLCG_04458 3.6e-74 yybC
GPNPHLCG_04459 1.9e-126 S Metallo-beta-lactamase superfamily
GPNPHLCG_04460 5.6e-77 yybA 2.3.1.57 K transcriptional
GPNPHLCG_04461 1.2e-71 yjcF S Acetyltransferase (GNAT) domain
GPNPHLCG_04462 2.5e-96 yyaS S Membrane
GPNPHLCG_04463 7.9e-91 yyaR K Acetyltransferase (GNAT) domain
GPNPHLCG_04464 1e-65 yyaQ S YjbR
GPNPHLCG_04465 6.1e-105 yyaP 1.5.1.3 H RibD C-terminal domain
GPNPHLCG_04466 7.1e-248 tetL EGP Major facilitator Superfamily
GPNPHLCG_04468 7.5e-10 S Putative amidase domain
GPNPHLCG_04469 5.1e-61 yyaN K MerR HTH family regulatory protein
GPNPHLCG_04470 4.4e-161 yyaM EG EamA-like transporter family
GPNPHLCG_04471 3.4e-21 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GPNPHLCG_04472 9.7e-67 yrhP E LysE type translocator
GPNPHLCG_04473 4.4e-24 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GPNPHLCG_04474 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
GPNPHLCG_04475 8e-168 yyaK S CAAX protease self-immunity
GPNPHLCG_04476 1.1e-125 EGP Major facilitator superfamily
GPNPHLCG_04477 2.4e-101 EGP Major facilitator superfamily
GPNPHLCG_04478 1.5e-92 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
GPNPHLCG_04479 1.4e-65 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
GPNPHLCG_04480 6.2e-179 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
GPNPHLCG_04481 1.2e-143 xth 3.1.11.2 L exodeoxyribonuclease III
GPNPHLCG_04482 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GPNPHLCG_04483 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
GPNPHLCG_04484 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
GPNPHLCG_04485 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
GPNPHLCG_04486 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
GPNPHLCG_04487 2.3e-33 yyzM S protein conserved in bacteria
GPNPHLCG_04488 8.1e-177 yyaD S Membrane
GPNPHLCG_04489 3.6e-111 yyaC S Sporulation protein YyaC
GPNPHLCG_04490 2.1e-149 spo0J K Belongs to the ParB family
GPNPHLCG_04491 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
GPNPHLCG_04492 9.6e-74 S Bacterial PH domain
GPNPHLCG_04493 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
GPNPHLCG_04494 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
GPNPHLCG_04495 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
GPNPHLCG_04496 3.7e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GPNPHLCG_04497 5.5e-107 jag S single-stranded nucleic acid binding R3H
GPNPHLCG_04498 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
GPNPHLCG_04499 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
GPNPHLCG_04500 6.7e-53 S Pfam Transposase IS66
GPNPHLCG_04501 2.1e-77 S Pfam Transposase IS66
GPNPHLCG_04502 1.7e-33 S Pfam Transposase IS66
GPNPHLCG_04503 3.2e-88 S Pfam Transposase IS66
GPNPHLCG_04504 1.7e-54
GPNPHLCG_04505 1.8e-10 M Pectate lyase superfamily protein
GPNPHLCG_04506 4.9e-50 S virus tail, fiber
GPNPHLCG_04508 1.9e-182 S N-acetylmuramoyl-L-alanine amidase activity
GPNPHLCG_04509 2.4e-37 S Bacteriophage holin
GPNPHLCG_04510 1.6e-189 S aspartate phosphatase
GPNPHLCG_04512 2.5e-184 L COG3328 Transposase and inactivated derivatives
GPNPHLCG_04513 1.5e-231 S impB/mucB/samB family C-terminal domain
GPNPHLCG_04514 4.6e-52 S YolD-like protein
GPNPHLCG_04515 4e-59 L nuclease activity
GPNPHLCG_04517 1.6e-63 S SMI1-KNR4 cell-wall
GPNPHLCG_04518 1.8e-275 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
GPNPHLCG_04519 1.4e-71 yokH G SMI1 / KNR4 family
GPNPHLCG_04520 4e-306 yokA L Recombinase
GPNPHLCG_04522 2.7e-100 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
GPNPHLCG_04523 1.3e-10 K Cro/C1-type HTH DNA-binding domain
GPNPHLCG_04536 6.5e-164 S Calcineurin-like phosphoesterase
GPNPHLCG_04537 2.5e-30 sspB S spore protein
GPNPHLCG_04540 7e-36
GPNPHLCG_04543 7e-49 S Thymidylate synthase
GPNPHLCG_04544 9.8e-52 S Thymidylate synthase
GPNPHLCG_04551 3.3e-13 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
GPNPHLCG_04553 5.6e-24 L HNH endonuclease
GPNPHLCG_04554 3.6e-36 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GPNPHLCG_04555 2.8e-91 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
GPNPHLCG_04556 9.2e-107 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GPNPHLCG_04557 7.9e-11 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
GPNPHLCG_04559 2.2e-21 polX L COG1796 DNA polymerase IV (family X)
GPNPHLCG_04560 3.5e-47 polX L COG1796 DNA polymerase IV (family X)
GPNPHLCG_04561 3.3e-153 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNPHLCG_04562 5.3e-26 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNPHLCG_04563 3.5e-53 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
GPNPHLCG_04564 1.4e-60 yshE S membrane
GPNPHLCG_04565 2.5e-181 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNPHLCG_04566 8.5e-78 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
GPNPHLCG_04567 9.8e-26 fadR K Transcriptional regulator
GPNPHLCG_04568 1.1e-60 fadR K Transcriptional regulator
GPNPHLCG_04569 1e-134 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
GPNPHLCG_04570 5.8e-95 etfB C Electron transfer flavoprotein
GPNPHLCG_04571 1.8e-176 etfA C Electron transfer flavoprotein
GPNPHLCG_04573 2e-301 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
GPNPHLCG_04574 2e-52 trxA O Belongs to the thioredoxin family
GPNPHLCG_04575 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
GPNPHLCG_04576 6.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
GPNPHLCG_04577 1.2e-79 yslB S Protein of unknown function (DUF2507)
GPNPHLCG_04578 2.4e-107 sdhC C succinate dehydrogenase
GPNPHLCG_04579 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNPHLCG_04580 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
GPNPHLCG_04581 1.6e-76 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
GPNPHLCG_04582 3.3e-30 gerE K Transcriptional regulator
GPNPHLCG_04583 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
GPNPHLCG_04584 9.6e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
GPNPHLCG_04585 4.2e-195 gerM S COG5401 Spore germination protein
GPNPHLCG_04586 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GPNPHLCG_04587 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GPNPHLCG_04588 5.3e-92 ysnB S Phosphoesterase
GPNPHLCG_04590 1.4e-45 L transposase activity
GPNPHLCG_04591 2.5e-144 L Molecular Function DNA binding, Biological Process DNA recombination
GPNPHLCG_04592 1.2e-130 ysnF S protein conserved in bacteria
GPNPHLCG_04593 4.9e-158 G Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
GPNPHLCG_04594 3.7e-32 ysnE K acetyltransferase
GPNPHLCG_04595 9.2e-15 ysnE K acetyltransferase
GPNPHLCG_04597 0.0 ilvB 2.2.1.6 E Acetolactate synthase
GPNPHLCG_04598 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
GPNPHLCG_04599 2e-40 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPNPHLCG_04600 5.2e-113 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GPNPHLCG_04601 3e-60 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPNPHLCG_04602 5.1e-55 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPNPHLCG_04603 1.5e-80 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GPNPHLCG_04604 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
GPNPHLCG_04605 2.7e-148 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNPHLCG_04606 4.9e-47 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNPHLCG_04607 5.3e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GPNPHLCG_04608 2e-64 yodN
GPNPHLCG_04609 7.5e-20 yodN
GPNPHLCG_04610 7.4e-30 yozE S Belongs to the UPF0346 family
GPNPHLCG_04611 3.9e-18 yokU S YokU-like protein, putative antitoxin
GPNPHLCG_04612 2.2e-32 kamA 5.4.3.2 E lysine 2,3-aminomutase
GPNPHLCG_04613 5.8e-160 kamA 5.4.3.2 E lysine 2,3-aminomutase
GPNPHLCG_04614 3.9e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
GPNPHLCG_04615 2.1e-257 yodQ 3.5.1.16 E Acetylornithine deacetylase
GPNPHLCG_04616 6.8e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
GPNPHLCG_04617 4.9e-125 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GPNPHLCG_04618 8.1e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GPNPHLCG_04620 1.8e-144 yiiD K acetyltransferase
GPNPHLCG_04621 1.9e-255 cgeD M maturation of the outermost layer of the spore
GPNPHLCG_04622 3.3e-36 cgeC
GPNPHLCG_04623 4.8e-64 cgeA
GPNPHLCG_04624 1.4e-186 cgeB S Spore maturation protein
GPNPHLCG_04625 6.4e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
GPNPHLCG_04626 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
GPNPHLCG_04627 1.3e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
GPNPHLCG_04628 3.5e-102 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GPNPHLCG_04629 1.6e-70 ypoP K transcriptional
GPNPHLCG_04630 1.9e-221 mepA V MATE efflux family protein
GPNPHLCG_04631 1.2e-28 ypmT S Uncharacterized ympT
GPNPHLCG_04632 1.1e-98 ypmS S protein conserved in bacteria
GPNPHLCG_04633 3.7e-137 ypmR E GDSL-like Lipase/Acylhydrolase
GPNPHLCG_04634 3.5e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
GPNPHLCG_04635 3.1e-40 ypmP S Protein of unknown function (DUF2535)
GPNPHLCG_04636 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GPNPHLCG_04637 3.4e-183 pspF K Transcriptional regulator
GPNPHLCG_04638 4.2e-110 hlyIII S protein, Hemolysin III
GPNPHLCG_04639 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
GPNPHLCG_04640 1.4e-92 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GPNPHLCG_04641 3.7e-87 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
GPNPHLCG_04642 4.3e-112 ypjP S YpjP-like protein
GPNPHLCG_04643 1.6e-143 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
GPNPHLCG_04644 1.7e-75 yphP S Belongs to the UPF0403 family
GPNPHLCG_04645 7.4e-262 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
GPNPHLCG_04646 9.8e-21 ypgR C Scaffold protein Nfu/NifU N terminal
GPNPHLCG_04647 5.7e-29 ypgR C COG0694 Thioredoxin-like proteins and domains
GPNPHLCG_04648 3.5e-39 ypgR C COG0694 Thioredoxin-like proteins and domains
GPNPHLCG_04650 2.1e-36 ypgQ S phosphohydrolase
GPNPHLCG_04651 1.1e-87 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPNPHLCG_04652 1.6e-60 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GPNPHLCG_04653 1e-21 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GPNPHLCG_04654 7.2e-54 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
GPNPHLCG_04655 3e-09 cspD K Cold-shock protein
GPNPHLCG_04656 3.8e-16 degR

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)