ORF_ID e_value Gene_name EC_number CAZy COGs Description
PMNHDPHM_00001 1.9e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
PMNHDPHM_00002 5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMNHDPHM_00003 1.8e-201 yacL S domain protein
PMNHDPHM_00004 1e-116 K sequence-specific DNA binding
PMNHDPHM_00005 2.2e-230 inlJ M MucBP domain
PMNHDPHM_00006 7.2e-300 V ABC transporter transmembrane region
PMNHDPHM_00007 2.6e-62 K helix_turn_helix gluconate operon transcriptional repressor
PMNHDPHM_00008 5.3e-160 S Membrane
PMNHDPHM_00009 1.1e-147 yhfC S Putative membrane peptidase family (DUF2324)
PMNHDPHM_00010 3.3e-259 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMNHDPHM_00012 2.8e-105
PMNHDPHM_00013 3.4e-149 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
PMNHDPHM_00014 1e-105 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
PMNHDPHM_00015 4.9e-162 K sequence-specific DNA binding
PMNHDPHM_00016 1.2e-274 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMNHDPHM_00017 5.5e-74 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PMNHDPHM_00018 3.2e-144 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMNHDPHM_00019 1.2e-97 yacP S YacP-like NYN domain
PMNHDPHM_00020 6.5e-193 XK27_00915 C Luciferase-like monooxygenase
PMNHDPHM_00021 9.2e-124 1.5.1.40 S Rossmann-like domain
PMNHDPHM_00022 1.4e-198
PMNHDPHM_00023 4.9e-224
PMNHDPHM_00024 2.5e-158 V ATPases associated with a variety of cellular activities
PMNHDPHM_00025 1.3e-165
PMNHDPHM_00026 3.5e-97
PMNHDPHM_00027 2.6e-154 T Calcineurin-like phosphoesterase superfamily domain
PMNHDPHM_00028 2.3e-84
PMNHDPHM_00029 4.5e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMNHDPHM_00030 5.2e-99 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
PMNHDPHM_00031 1.7e-81 ynhH S NusG domain II
PMNHDPHM_00032 0.0 ndh 1.6.99.3 C NADH dehydrogenase
PMNHDPHM_00033 4.6e-139 cad S FMN_bind
PMNHDPHM_00034 3.3e-230 tnpB L Putative transposase DNA-binding domain
PMNHDPHM_00035 8.8e-198 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMNHDPHM_00036 3.2e-167 menA 2.5.1.74 M UbiA prenyltransferase family
PMNHDPHM_00037 2.3e-173 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PMNHDPHM_00038 8.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PMNHDPHM_00039 1.5e-22 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PMNHDPHM_00040 1.5e-100 nusG K Participates in transcription elongation, termination and antitermination
PMNHDPHM_00041 1.3e-159 S Alpha/beta hydrolase of unknown function (DUF915)
PMNHDPHM_00042 5.9e-79 F nucleoside 2-deoxyribosyltransferase
PMNHDPHM_00043 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
PMNHDPHM_00044 3.1e-63 S Domain of unknown function (DUF4430)
PMNHDPHM_00045 1.3e-88 S ECF transporter, substrate-specific component
PMNHDPHM_00046 9.2e-95 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
PMNHDPHM_00047 1.1e-272 nylA 3.5.1.4 J Belongs to the amidase family
PMNHDPHM_00048 1.1e-49 HA62_12640 S GCN5-related N-acetyl-transferase
PMNHDPHM_00049 4.2e-258 pepC 3.4.22.40 E aminopeptidase
PMNHDPHM_00050 3.8e-262 pepC 3.4.22.40 E Peptidase C1-like family
PMNHDPHM_00051 1.1e-198
PMNHDPHM_00052 9.2e-212 S ABC-2 family transporter protein
PMNHDPHM_00053 1.9e-166 V ATPases associated with a variety of cellular activities
PMNHDPHM_00054 0.0 kup P Transport of potassium into the cell
PMNHDPHM_00055 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
PMNHDPHM_00056 1.8e-93 ccpN K Domain in cystathionine beta-synthase and other proteins.
PMNHDPHM_00057 2.9e-122 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMNHDPHM_00058 5.6e-203 ltrA S Bacterial low temperature requirement A protein (LtrA)
PMNHDPHM_00059 7.2e-46
PMNHDPHM_00060 1.1e-195 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
PMNHDPHM_00061 8.8e-09 yhjA S CsbD-like
PMNHDPHM_00064 5.4e-08
PMNHDPHM_00065 2.5e-32
PMNHDPHM_00066 3.7e-34
PMNHDPHM_00067 4.9e-224 pimH EGP Major facilitator Superfamily
PMNHDPHM_00068 1.3e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PMNHDPHM_00069 5.4e-150 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PMNHDPHM_00071 3.8e-96
PMNHDPHM_00072 2.8e-135 3.4.22.70 M Sortase family
PMNHDPHM_00073 5.4e-297 M Cna protein B-type domain
PMNHDPHM_00074 1.3e-265 M domain protein
PMNHDPHM_00075 0.0 M domain protein
PMNHDPHM_00076 3.3e-103
PMNHDPHM_00077 1.3e-232 N Uncharacterized conserved protein (DUF2075)
PMNHDPHM_00078 5.5e-208 MA20_36090 S Protein of unknown function (DUF2974)
PMNHDPHM_00079 9.1e-113 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_00080 1.4e-56 K Transcriptional regulator PadR-like family
PMNHDPHM_00081 2.6e-138
PMNHDPHM_00082 7.5e-138
PMNHDPHM_00083 3.3e-46 S Enterocin A Immunity
PMNHDPHM_00084 8.4e-188 tas C Aldo/keto reductase family
PMNHDPHM_00085 1.1e-253 yjjP S Putative threonine/serine exporter
PMNHDPHM_00086 7e-59
PMNHDPHM_00087 9.9e-234 mesE M Transport protein ComB
PMNHDPHM_00088 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PMNHDPHM_00090 2.3e-219 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PMNHDPHM_00091 2.8e-140 plnD K LytTr DNA-binding domain
PMNHDPHM_00094 1.5e-46 spiA S Enterocin A Immunity
PMNHDPHM_00095 9e-22
PMNHDPHM_00099 1.6e-138 S CAAX protease self-immunity
PMNHDPHM_00100 1e-70 K Transcriptional regulator
PMNHDPHM_00101 2e-253 EGP Major Facilitator Superfamily
PMNHDPHM_00102 2.2e-54
PMNHDPHM_00103 1e-54 S Enterocin A Immunity
PMNHDPHM_00104 3e-181 S Aldo keto reductase
PMNHDPHM_00105 3.2e-130 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMNHDPHM_00106 1.8e-217 yqiG C Oxidoreductase
PMNHDPHM_00107 6e-17 S Short C-terminal domain
PMNHDPHM_00108 2.1e-255 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
PMNHDPHM_00109 4.4e-136
PMNHDPHM_00110 2.3e-18
PMNHDPHM_00111 5.3e-279 mntH P H( )-stimulated, divalent metal cation uptake system
PMNHDPHM_00112 0.0 pacL P P-type ATPase
PMNHDPHM_00113 9.8e-64
PMNHDPHM_00114 4.1e-240 EGP Major Facilitator Superfamily
PMNHDPHM_00115 0.0 mco Q Multicopper oxidase
PMNHDPHM_00116 1e-24
PMNHDPHM_00117 9e-113 2.5.1.105 P Cation efflux family
PMNHDPHM_00118 8.7e-51 czrA K Transcriptional regulator, ArsR family
PMNHDPHM_00119 1.1e-175 sitA P Belongs to the bacterial solute-binding protein 9 family
PMNHDPHM_00120 9.5e-145 mtsB U ABC 3 transport family
PMNHDPHM_00121 1.3e-131 mntB 3.6.3.35 P ABC transporter
PMNHDPHM_00122 2.7e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMNHDPHM_00123 2e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
PMNHDPHM_00124 1.4e-118 GM NmrA-like family
PMNHDPHM_00125 1.7e-85
PMNHDPHM_00126 1.4e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
PMNHDPHM_00127 4.7e-20
PMNHDPHM_00129 2.3e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMNHDPHM_00130 1.1e-68 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMNHDPHM_00131 1.4e-286 G MFS/sugar transport protein
PMNHDPHM_00132 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase concanavalin-like domain
PMNHDPHM_00133 2.5e-170 ssuA P NMT1-like family
PMNHDPHM_00134 2.9e-295 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
PMNHDPHM_00135 5.6e-236 yfiQ I Acyltransferase family
PMNHDPHM_00136 4e-122 ssuB P ATPases associated with a variety of cellular activities
PMNHDPHM_00137 7.1e-147 ssuC U Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00138 5.3e-124 S B3/4 domain
PMNHDPHM_00139 0.0 V ABC transporter
PMNHDPHM_00140 0.0 V ATPases associated with a variety of cellular activities
PMNHDPHM_00141 1e-210 EGP Transmembrane secretion effector
PMNHDPHM_00142 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMNHDPHM_00143 6.1e-210
PMNHDPHM_00144 4e-43 yrzL S Belongs to the UPF0297 family
PMNHDPHM_00145 9.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PMNHDPHM_00146 2.3e-53 yrzB S Belongs to the UPF0473 family
PMNHDPHM_00147 2e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PMNHDPHM_00148 8.6e-93 cvpA S Colicin V production protein
PMNHDPHM_00149 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PMNHDPHM_00150 6.6e-53 trxA O Belongs to the thioredoxin family
PMNHDPHM_00151 8.5e-295 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMNHDPHM_00152 1.8e-239 dltB M MBOAT, membrane-bound O-acyltransferase family
PMNHDPHM_00153 4e-37 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PMNHDPHM_00154 5.5e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PMNHDPHM_00155 1.1e-83 yslB S Protein of unknown function (DUF2507)
PMNHDPHM_00156 5.3e-278 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PMNHDPHM_00157 2.2e-96 S Phosphoesterase
PMNHDPHM_00158 5.2e-133 gla U Major intrinsic protein
PMNHDPHM_00159 3.5e-85 ykuL S CBS domain
PMNHDPHM_00160 2e-158 XK27_00890 S Domain of unknown function (DUF368)
PMNHDPHM_00161 6.3e-157 ykuT M mechanosensitive ion channel
PMNHDPHM_00162 6e-115 S Protein of unknown function (DUF969)
PMNHDPHM_00163 3.7e-130 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMNHDPHM_00164 7.9e-65 asp2 S Asp23 family, cell envelope-related function
PMNHDPHM_00165 5.1e-61 asp23 S Asp23 family, cell envelope-related function
PMNHDPHM_00166 1.9e-29
PMNHDPHM_00167 1.5e-89 S Protein conserved in bacteria
PMNHDPHM_00168 6.4e-38 S Transglycosylase associated protein
PMNHDPHM_00169 9.1e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
PMNHDPHM_00170 4e-173 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMNHDPHM_00171 6.7e-27
PMNHDPHM_00172 3.4e-36
PMNHDPHM_00173 6.4e-84 fld C Flavodoxin
PMNHDPHM_00174 5.5e-52
PMNHDPHM_00175 2.2e-65
PMNHDPHM_00177 2.7e-56 ywjH S Protein of unknown function (DUF1634)
PMNHDPHM_00178 1.1e-129 yxaA S Sulfite exporter TauE/SafE
PMNHDPHM_00179 1.8e-237 S TPM domain
PMNHDPHM_00180 1.7e-116
PMNHDPHM_00181 3.2e-261 nox 1.6.3.4 C NADH oxidase
PMNHDPHM_00182 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
PMNHDPHM_00183 9.3e-164 gadR K Transcriptional activator, Rgg GadR MutR family
PMNHDPHM_00184 4.9e-285 V ABC transporter transmembrane region
PMNHDPHM_00185 2.1e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
PMNHDPHM_00186 7.8e-82 S NUDIX domain
PMNHDPHM_00187 4.8e-79
PMNHDPHM_00188 1.1e-118 V ATPases associated with a variety of cellular activities
PMNHDPHM_00189 2.2e-123
PMNHDPHM_00190 4.6e-118
PMNHDPHM_00191 6.1e-77
PMNHDPHM_00192 1.8e-303 oppA E ABC transporter, substratebinding protein
PMNHDPHM_00193 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
PMNHDPHM_00195 3.6e-18
PMNHDPHM_00196 1.9e-256 bmr3 EGP Major facilitator Superfamily
PMNHDPHM_00197 1.4e-138 magIII L Base excision DNA repair protein, HhH-GPD family
PMNHDPHM_00198 6.7e-161 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
PMNHDPHM_00199 2.5e-242 sgaT 2.7.1.194 S PTS system sugar-specific permease component
PMNHDPHM_00200 6.4e-162 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PMNHDPHM_00201 4.2e-286 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
PMNHDPHM_00202 1.1e-133 K DeoR C terminal sensor domain
PMNHDPHM_00203 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMNHDPHM_00204 1.4e-253 rarA L recombination factor protein RarA
PMNHDPHM_00205 9.4e-58
PMNHDPHM_00206 6.7e-176 yhaI S Protein of unknown function (DUF805)
PMNHDPHM_00207 2.6e-272 L Mga helix-turn-helix domain
PMNHDPHM_00209 1.1e-184 ynjC S Cell surface protein
PMNHDPHM_00210 2.2e-124 yqcC S WxL domain surface cell wall-binding
PMNHDPHM_00212 0.0
PMNHDPHM_00213 5.6e-106 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PMNHDPHM_00214 2.7e-43
PMNHDPHM_00215 1.7e-192 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PMNHDPHM_00216 3.4e-163 K LysR substrate binding domain
PMNHDPHM_00217 3.6e-257 S Sulphur transport
PMNHDPHM_00218 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
PMNHDPHM_00219 2.9e-142 tauC P Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00220 2.6e-183 tauA P NMT1-like family
PMNHDPHM_00221 5.4e-138 tauB 3.6.3.36 P ATPases associated with a variety of cellular activities
PMNHDPHM_00224 3.3e-55 S DsrE/DsrF-like family
PMNHDPHM_00225 1.4e-254 pbuO S permease
PMNHDPHM_00226 3e-54 S Protein of unknown function (DUF1516)
PMNHDPHM_00227 8.1e-58 ypaA S Protein of unknown function (DUF1304)
PMNHDPHM_00228 5.9e-43
PMNHDPHM_00229 1.5e-132 K UTRA
PMNHDPHM_00230 3.2e-291 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_00231 7.2e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_00232 6.1e-85
PMNHDPHM_00233 2.6e-52 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_00234 4.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_00235 1.1e-192 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMNHDPHM_00236 2e-91 ogt 2.1.1.63 L Methyltransferase
PMNHDPHM_00237 1.6e-120 K Transcriptional regulatory protein, C terminal
PMNHDPHM_00238 3.5e-202 T PhoQ Sensor
PMNHDPHM_00239 2.5e-86
PMNHDPHM_00240 2.5e-49 tnp2PF3 L Transposase DDE domain
PMNHDPHM_00241 9.2e-220 yttB EGP Major facilitator Superfamily
PMNHDPHM_00242 8.4e-148 cof S Sucrose-6F-phosphate phosphohydrolase
PMNHDPHM_00243 1.7e-167 S Polyphosphate nucleotide phosphotransferase, PPK2 family
PMNHDPHM_00244 0.0 pepO 3.4.24.71 O Peptidase family M13
PMNHDPHM_00245 2.9e-81 K Acetyltransferase (GNAT) domain
PMNHDPHM_00246 1.2e-165 degV S Uncharacterised protein, DegV family COG1307
PMNHDPHM_00247 1.3e-120 qmcA O prohibitin homologues
PMNHDPHM_00248 8.4e-30
PMNHDPHM_00249 2e-120 lys M Glycosyl hydrolases family 25
PMNHDPHM_00250 1.1e-59 S Protein of unknown function (DUF1093)
PMNHDPHM_00251 2e-61 S Domain of unknown function (DUF4828)
PMNHDPHM_00252 7e-178 mocA S Oxidoreductase
PMNHDPHM_00253 3.9e-240 yfmL 3.6.4.13 L DEAD DEAH box helicase
PMNHDPHM_00254 6.8e-48 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_00256 1.9e-71 S Domain of unknown function (DUF3284)
PMNHDPHM_00258 2e-07
PMNHDPHM_00259 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMNHDPHM_00260 2.8e-240 pepS E Thermophilic metalloprotease (M29)
PMNHDPHM_00261 2.7e-111 K Bacterial regulatory proteins, tetR family
PMNHDPHM_00262 5.6e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
PMNHDPHM_00263 4.6e-180 yihY S Belongs to the UPF0761 family
PMNHDPHM_00264 1.9e-80 fld C Flavodoxin
PMNHDPHM_00265 2.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
PMNHDPHM_00266 1.1e-197 M Glycosyltransferase like family 2
PMNHDPHM_00268 4.5e-29
PMNHDPHM_00269 6.2e-199 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PMNHDPHM_00270 4.7e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PMNHDPHM_00271 1.4e-97 N domain, Protein
PMNHDPHM_00272 1.5e-296 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_00273 0.0 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMNHDPHM_00274 0.0 S Bacterial membrane protein YfhO
PMNHDPHM_00275 0.0 S Psort location CytoplasmicMembrane, score
PMNHDPHM_00276 5e-173 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
PMNHDPHM_00277 2.1e-109
PMNHDPHM_00278 3e-168 yqjA S Putative aromatic acid exporter C-terminal domain
PMNHDPHM_00279 2.1e-31 cspC K Cold shock protein
PMNHDPHM_00280 6.5e-20 chpR T PFAM SpoVT AbrB
PMNHDPHM_00281 9.9e-83 yvbK 3.1.3.25 K GNAT family
PMNHDPHM_00282 1.6e-109 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
PMNHDPHM_00283 1.2e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PMNHDPHM_00284 7.3e-242 pbuX F xanthine permease
PMNHDPHM_00285 7.8e-205 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMNHDPHM_00286 1.6e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PMNHDPHM_00288 1.2e-103
PMNHDPHM_00289 4.2e-130
PMNHDPHM_00290 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMNHDPHM_00291 3.9e-110 vanZ V VanZ like family
PMNHDPHM_00292 4.5e-152 glcU U sugar transport
PMNHDPHM_00293 4.3e-258 pgi 5.3.1.9 G Belongs to the GPI family
PMNHDPHM_00294 1.7e-226 L Pfam:Integrase_AP2
PMNHDPHM_00296 4.6e-180
PMNHDPHM_00297 4.7e-31
PMNHDPHM_00298 2e-60 S Pyridoxamine 5'-phosphate oxidase
PMNHDPHM_00301 4.4e-10
PMNHDPHM_00302 6.8e-98 S Domain of Unknown Function with PDB structure (DUF3862)
PMNHDPHM_00303 1.8e-77 E Zn peptidase
PMNHDPHM_00304 3.4e-55 3.4.21.88 K Helix-turn-helix domain
PMNHDPHM_00305 2e-36 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_00309 4.8e-99
PMNHDPHM_00311 1.7e-15
PMNHDPHM_00314 9.6e-158 recT L RecT family
PMNHDPHM_00315 5.9e-134 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
PMNHDPHM_00316 1.6e-145 L Replication initiation and membrane attachment
PMNHDPHM_00317 1.9e-70 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PMNHDPHM_00320 1.3e-73
PMNHDPHM_00321 3.4e-39
PMNHDPHM_00322 4.4e-58 rusA L Endodeoxyribonuclease RusA
PMNHDPHM_00323 1.1e-49 tnp2PF3 L Transposase DDE domain
PMNHDPHM_00324 1.4e-281 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PMNHDPHM_00325 1.1e-300 2.4.1.52 GT4 M Glycosyl transferases group 1
PMNHDPHM_00327 0.0 2.4.1.9, 3.4.24.40 GH68 S peptidase inhibitor activity
PMNHDPHM_00329 1.6e-293
PMNHDPHM_00330 1.2e-131
PMNHDPHM_00331 6.9e-192
PMNHDPHM_00332 1.4e-152 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
PMNHDPHM_00333 1.2e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
PMNHDPHM_00334 3.7e-90 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMNHDPHM_00335 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PMNHDPHM_00336 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
PMNHDPHM_00337 7.1e-62
PMNHDPHM_00338 1.9e-83 6.3.3.2 S ASCH
PMNHDPHM_00339 1.6e-32
PMNHDPHM_00340 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PMNHDPHM_00341 4.1e-188 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PMNHDPHM_00342 1e-286 dnaK O Heat shock 70 kDa protein
PMNHDPHM_00343 1.4e-99 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PMNHDPHM_00344 8.4e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PMNHDPHM_00346 1.1e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
PMNHDPHM_00347 1.3e-176 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PMNHDPHM_00348 5.8e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PMNHDPHM_00349 6.7e-119 terC P membrane
PMNHDPHM_00350 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PMNHDPHM_00351 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PMNHDPHM_00352 5.4e-44 ylxQ J ribosomal protein
PMNHDPHM_00353 1.5e-46 ylxR K Protein of unknown function (DUF448)
PMNHDPHM_00354 7.9e-211 nusA K Participates in both transcription termination and antitermination
PMNHDPHM_00355 1e-84 rimP J Required for maturation of 30S ribosomal subunits
PMNHDPHM_00356 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMNHDPHM_00357 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PMNHDPHM_00358 1.1e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PMNHDPHM_00359 4.3e-141 cdsA 2.7.7.41 S Belongs to the CDS family
PMNHDPHM_00360 1.7e-139 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMNHDPHM_00361 0.0 yvcC M Cna protein B-type domain
PMNHDPHM_00362 2.9e-128 M domain protein
PMNHDPHM_00363 3.3e-186 M LPXTG cell wall anchor motif
PMNHDPHM_00364 9.2e-203 3.4.22.70 M Sortase family
PMNHDPHM_00365 6.1e-67 pdxH S Pyridoxamine 5'-phosphate oxidase
PMNHDPHM_00366 1.8e-88
PMNHDPHM_00367 3.2e-46 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
PMNHDPHM_00368 2.6e-115 L Resolvase, N terminal domain
PMNHDPHM_00370 1.5e-177 L Transposase and inactivated derivatives, IS30 family
PMNHDPHM_00371 8.8e-305 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
PMNHDPHM_00372 9.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
PMNHDPHM_00374 8.5e-148 cbiQ P cobalt transport
PMNHDPHM_00375 0.0 3.6.3.24 P ATP-binding cassette cobalt transporter
PMNHDPHM_00376 2.7e-97 S UPF0397 protein
PMNHDPHM_00377 2.8e-159 salL 2.5.1.63, 2.5.1.94 K S-adenosyl-l-methionine hydroxide adenosyltransferase
PMNHDPHM_00378 8.2e-240 yhfW G Metalloenzyme superfamily
PMNHDPHM_00379 1.6e-221 yhfX E Alanine racemase, N-terminal domain
PMNHDPHM_00380 2.2e-207 bioF 2.3.1.47, 2.8.1.6 E Cys/Met metabolism PLP-dependent enzyme
PMNHDPHM_00381 5.7e-166 php S Phosphotriesterase family
PMNHDPHM_00382 1e-192 yhfT S Protein of unknown function
PMNHDPHM_00383 3e-57 yhfU S Protein of unknown function DUF2620
PMNHDPHM_00384 7.3e-08
PMNHDPHM_00385 8.7e-170 P YhfZ C-terminal domain
PMNHDPHM_00386 5.8e-170 K helix_turn _helix lactose operon repressor
PMNHDPHM_00387 7.9e-126 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
PMNHDPHM_00388 1.6e-310 G PTS system sorbose-specific iic component
PMNHDPHM_00389 3.9e-72 2.7.1.191 G PTS system fructose IIA component
PMNHDPHM_00390 1.6e-82 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_00391 1.5e-169 fba 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PMNHDPHM_00392 1.2e-146 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PMNHDPHM_00393 6.6e-128 WQ51_05710 S Mitochondrial biogenesis AIM24
PMNHDPHM_00394 2.3e-150 S Alpha/beta hydrolase family
PMNHDPHM_00395 3.2e-104 K Bacterial regulatory proteins, tetR family
PMNHDPHM_00396 1.6e-176 XK27_06930 V domain protein
PMNHDPHM_00397 4.4e-28
PMNHDPHM_00398 1.5e-94 S Protein of unknown function (DUF1642)
PMNHDPHM_00402 2.8e-63
PMNHDPHM_00405 9.1e-77
PMNHDPHM_00406 4.5e-224 S GcrA cell cycle regulator
PMNHDPHM_00407 4.8e-107 L NUMOD4 motif
PMNHDPHM_00408 2.7e-57
PMNHDPHM_00409 6.6e-77 ps333 L Terminase small subunit
PMNHDPHM_00410 6.7e-267 S Terminase RNAseH like domain
PMNHDPHM_00411 1.2e-261 S Phage portal protein
PMNHDPHM_00412 6.1e-185 S head morphogenesis protein, SPP1 gp7 family
PMNHDPHM_00413 3.8e-98 S Domain of unknown function (DUF4355)
PMNHDPHM_00414 4.3e-186 gpG
PMNHDPHM_00415 1.5e-62 S Phage gp6-like head-tail connector protein
PMNHDPHM_00416 1.2e-51
PMNHDPHM_00417 2.9e-51 S Bacteriophage HK97-gp10, putative tail-component
PMNHDPHM_00418 7.8e-70 S Protein of unknown function (DUF3168)
PMNHDPHM_00419 3.7e-108 S Phage tail tube protein
PMNHDPHM_00420 3e-51 S Phage tail assembly chaperone protein, TAC
PMNHDPHM_00421 6.6e-57
PMNHDPHM_00422 0.0 S phage tail tape measure protein
PMNHDPHM_00423 0.0 S Phage tail protein
PMNHDPHM_00424 0.0 S cellulase activity
PMNHDPHM_00425 7.6e-52
PMNHDPHM_00427 6.1e-48
PMNHDPHM_00428 2e-44 hol S Bacteriophage holin
PMNHDPHM_00429 1.6e-233 M Glycosyl hydrolases family 25
PMNHDPHM_00430 2.9e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
PMNHDPHM_00431 2.3e-116 F DNA/RNA non-specific endonuclease
PMNHDPHM_00432 1.7e-78 yttA 2.7.13.3 S Pfam Transposase IS66
PMNHDPHM_00433 3e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
PMNHDPHM_00434 1.7e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
PMNHDPHM_00435 5.8e-85 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
PMNHDPHM_00439 1e-213 L PFAM transposase, IS4 family protein
PMNHDPHM_00441 1.2e-17
PMNHDPHM_00442 4.7e-97 yttB EGP Major facilitator Superfamily
PMNHDPHM_00443 2.2e-108 lmrP E Major Facilitator Superfamily
PMNHDPHM_00444 7.5e-285 pipD E Dipeptidase
PMNHDPHM_00446 8.7e-09
PMNHDPHM_00447 1.1e-133 G Phosphoglycerate mutase family
PMNHDPHM_00448 1.1e-121 K Bacterial regulatory proteins, tetR family
PMNHDPHM_00449 0.0 ycfI V ABC transporter, ATP-binding protein
PMNHDPHM_00450 0.0 yfiC V ABC transporter
PMNHDPHM_00451 1.9e-141 S NADPH-dependent FMN reductase
PMNHDPHM_00452 7.3e-166 1.13.11.2 S glyoxalase
PMNHDPHM_00453 9.2e-197 ampC V Beta-lactamase
PMNHDPHM_00454 4.5e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
PMNHDPHM_00455 2.7e-111 tdk 2.7.1.21 F thymidine kinase
PMNHDPHM_00456 4.8e-191 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMNHDPHM_00457 1.7e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PMNHDPHM_00458 3.1e-192 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PMNHDPHM_00459 2e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PMNHDPHM_00460 4.4e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMNHDPHM_00461 1e-125 atpB C it plays a direct role in the translocation of protons across the membrane
PMNHDPHM_00462 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMNHDPHM_00463 1.5e-54 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMNHDPHM_00464 7e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMNHDPHM_00465 7.2e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PMNHDPHM_00466 1.2e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PMNHDPHM_00467 3.3e-10
PMNHDPHM_00468 2.3e-249 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PMNHDPHM_00469 1.6e-52 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PMNHDPHM_00470 0.0 S PglZ domain
PMNHDPHM_00471 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
PMNHDPHM_00472 0.0 S Protein of unknown function (DUF1524)
PMNHDPHM_00473 1.9e-123
PMNHDPHM_00474 3.8e-224 F Permease for cytosine/purines, uracil, thiamine, allantoin
PMNHDPHM_00475 3.1e-206 S Protein of unknown function (DUF917)
PMNHDPHM_00476 2.9e-290 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
PMNHDPHM_00478 0.0 G Phosphodiester glycosidase
PMNHDPHM_00479 2.4e-147 frlD 2.7.1.218 G pfkB family carbohydrate kinase
PMNHDPHM_00480 3.1e-102 S WxL domain surface cell wall-binding
PMNHDPHM_00481 3.2e-112
PMNHDPHM_00482 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
PMNHDPHM_00483 1.4e-136 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
PMNHDPHM_00484 1.9e-138 S Belongs to the UPF0246 family
PMNHDPHM_00485 0.0 rafA 3.2.1.22 G alpha-galactosidase
PMNHDPHM_00486 1.4e-270 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_00487 9.3e-71 S Domain of unknown function (DUF3284)
PMNHDPHM_00488 7.7e-213 S Bacterial protein of unknown function (DUF871)
PMNHDPHM_00489 9.5e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_00490 2.2e-102
PMNHDPHM_00491 1.5e-149 lutA C Cysteine-rich domain
PMNHDPHM_00492 1.6e-290 lutB C 4Fe-4S dicluster domain
PMNHDPHM_00493 4.3e-132 yrjD S LUD domain
PMNHDPHM_00494 4.5e-100 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMNHDPHM_00495 1.1e-256 EGP Major facilitator Superfamily
PMNHDPHM_00496 2.5e-305 oppA E ABC transporter, substratebinding protein
PMNHDPHM_00497 6.1e-163 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMNHDPHM_00498 1.4e-176 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
PMNHDPHM_00499 1.9e-197 oppD P Belongs to the ABC transporter superfamily
PMNHDPHM_00500 6.9e-181 oppF P Belongs to the ABC transporter superfamily
PMNHDPHM_00501 2.1e-117 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
PMNHDPHM_00502 5e-48 K Cro/C1-type HTH DNA-binding domain
PMNHDPHM_00503 4.8e-37 XK27_01315 S Protein of unknown function (DUF2829)
PMNHDPHM_00504 4.9e-128 IQ Enoyl-(Acyl carrier protein) reductase
PMNHDPHM_00505 4.9e-82 ccl S QueT transporter
PMNHDPHM_00506 1.4e-50 S Motility quorum-sensing regulator, toxin of MqsA
PMNHDPHM_00507 2.6e-177 ps301 K Protein of unknown function (DUF4065)
PMNHDPHM_00508 2e-132 E lipolytic protein G-D-S-L family
PMNHDPHM_00509 9.7e-161 epsB M biosynthesis protein
PMNHDPHM_00510 1e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
PMNHDPHM_00511 4.2e-220
PMNHDPHM_00512 6.6e-220 glf 5.4.99.9 M UDP-galactopyranose mutase
PMNHDPHM_00513 1.8e-254 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
PMNHDPHM_00514 5.3e-155 cps1D M Domain of unknown function (DUF4422)
PMNHDPHM_00515 6.1e-213 M Glycosyl transferases group 1
PMNHDPHM_00516 1.8e-170 rgpB GT2 M Glycosyl transferase family 2
PMNHDPHM_00517 2.4e-187 wbbI M transferase activity, transferring glycosyl groups
PMNHDPHM_00518 5.5e-214 M PFAM Glycosyl transferases group 1
PMNHDPHM_00519 7.5e-126 rfbP 2.7.8.6 M Bacterial sugar transferase
PMNHDPHM_00520 2.7e-35 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PMNHDPHM_00521 6.2e-214 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMNHDPHM_00522 3e-303 frvR K Mga helix-turn-helix domain
PMNHDPHM_00523 6.3e-298 frvR K Mga helix-turn-helix domain
PMNHDPHM_00524 5e-268 lysP E amino acid
PMNHDPHM_00526 3.6e-131 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
PMNHDPHM_00527 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PMNHDPHM_00528 1.6e-97
PMNHDPHM_00529 3.3e-100 2.3.1.128 J Acetyltransferase (GNAT) domain
PMNHDPHM_00530 2.7e-191 S Bacterial protein of unknown function (DUF916)
PMNHDPHM_00531 9.9e-103
PMNHDPHM_00532 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PMNHDPHM_00533 4.1e-245 Z012_01130 S Fic/DOC family
PMNHDPHM_00534 1.1e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PMNHDPHM_00535 1.5e-157 I alpha/beta hydrolase fold
PMNHDPHM_00536 3.9e-49
PMNHDPHM_00537 5.9e-70
PMNHDPHM_00538 1.7e-159 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
PMNHDPHM_00539 7.2e-124 citR K FCD
PMNHDPHM_00540 6.9e-267 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
PMNHDPHM_00541 5.2e-101 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
PMNHDPHM_00542 1.3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
PMNHDPHM_00543 6.9e-156 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
PMNHDPHM_00544 2.2e-48 citD C Covalent carrier of the coenzyme of citrate lyase
PMNHDPHM_00545 2.6e-183 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
PMNHDPHM_00547 1e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
PMNHDPHM_00548 1.8e-37 gcdC 2.3.1.12 I Biotin-requiring enzyme
PMNHDPHM_00549 5.8e-52
PMNHDPHM_00550 2.2e-241 citM C Citrate transporter
PMNHDPHM_00551 1.3e-41
PMNHDPHM_00552 1.8e-101 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
PMNHDPHM_00553 9.3e-89 K Acetyltransferase (GNAT) domain
PMNHDPHM_00554 2.4e-110 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PMNHDPHM_00555 9.9e-58 K Transcriptional regulator PadR-like family
PMNHDPHM_00556 4.6e-103 ORF00048
PMNHDPHM_00557 3.3e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PMNHDPHM_00558 4.4e-169 yjjC V ABC transporter
PMNHDPHM_00559 3.1e-287 M Exporter of polyketide antibiotics
PMNHDPHM_00560 7.3e-115 K Transcriptional regulator
PMNHDPHM_00561 2.4e-259 ypiB EGP Major facilitator Superfamily
PMNHDPHM_00562 6.7e-128 S membrane transporter protein
PMNHDPHM_00563 5.2e-187 K Helix-turn-helix domain
PMNHDPHM_00564 1.8e-164 S Alpha beta hydrolase
PMNHDPHM_00565 3.6e-61 yvoA_1 K Transcriptional regulator, GntR family
PMNHDPHM_00566 8.5e-128 skfE V ATPases associated with a variety of cellular activities
PMNHDPHM_00567 6.9e-21
PMNHDPHM_00568 3.1e-164 oppF P Oligopeptide/dipeptide transporter, C-terminal region
PMNHDPHM_00569 1.7e-201 oppD P Oligopeptide/dipeptide transporter, C-terminal region
PMNHDPHM_00570 4.4e-49
PMNHDPHM_00571 3e-173 amiD P N-terminal TM domain of oligopeptide transport permease C
PMNHDPHM_00572 1e-168 oppB P Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00573 0.0 E Bacterial extracellular solute-binding proteins, family 5 Middle
PMNHDPHM_00574 1.3e-38
PMNHDPHM_00575 1.1e-298 V ABC transporter transmembrane region
PMNHDPHM_00576 7e-292 V ABC transporter transmembrane region
PMNHDPHM_00577 6.5e-69 S Iron-sulphur cluster biosynthesis
PMNHDPHM_00578 0.0 XK27_08510 L Type III restriction protein res subunit
PMNHDPHM_00579 2.2e-162 2.7.1.39 S Phosphotransferase enzyme family
PMNHDPHM_00580 2.7e-116 zmp3 O Zinc-dependent metalloprotease
PMNHDPHM_00581 0.0 lytN 3.5.1.104 M LysM domain
PMNHDPHM_00583 3.2e-50 lciIC K Helix-turn-helix XRE-family like proteins
PMNHDPHM_00585 8e-304 L Reverse transcriptase (RNA-dependent DNA polymerase)
PMNHDPHM_00586 4.9e-168 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PMNHDPHM_00587 7.8e-180 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PMNHDPHM_00588 9.5e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PMNHDPHM_00589 4e-264 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PMNHDPHM_00590 3.2e-175
PMNHDPHM_00591 5.3e-141
PMNHDPHM_00592 9.7e-61 yitW S Iron-sulfur cluster assembly protein
PMNHDPHM_00593 1.9e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PMNHDPHM_00594 6.7e-276 V (ABC) transporter
PMNHDPHM_00595 0.0 V ABC transporter transmembrane region
PMNHDPHM_00596 1.1e-149 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PMNHDPHM_00597 4.5e-129 trmK 2.1.1.217 S SAM-dependent methyltransferase
PMNHDPHM_00598 4.4e-196 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PMNHDPHM_00599 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PMNHDPHM_00600 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PMNHDPHM_00601 1.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PMNHDPHM_00602 3.8e-226 sip L Phage integrase family
PMNHDPHM_00604 2.5e-70
PMNHDPHM_00605 1e-215 M Glycosyl hydrolases family 25
PMNHDPHM_00606 3.4e-47 S Bacteriophage holin of superfamily 6 (Holin_LLH)
PMNHDPHM_00607 4.9e-31
PMNHDPHM_00609 1e-51
PMNHDPHM_00610 0.0 S cellulase activity
PMNHDPHM_00611 0.0
PMNHDPHM_00612 0.0 xkdO M Phage tail tape measure protein TP901
PMNHDPHM_00613 1.9e-36
PMNHDPHM_00614 2.1e-55 S Phage tail assembly chaperone proteins, TAC
PMNHDPHM_00615 2.1e-114 S Phage tail tube protein
PMNHDPHM_00616 3.2e-65 S Protein of unknown function (DUF806)
PMNHDPHM_00617 5.6e-71 S Bacteriophage HK97-gp10, putative tail-component
PMNHDPHM_00618 1.6e-55 S Phage head-tail joining protein
PMNHDPHM_00619 2.7e-32
PMNHDPHM_00620 2.5e-251 S Phage capsid family
PMNHDPHM_00621 3.6e-202 S Phage portal protein
PMNHDPHM_00623 0.0 S Phage Terminase
PMNHDPHM_00624 2.1e-79 L Phage terminase, small subunit
PMNHDPHM_00625 2.5e-98 L Resolvase, N terminal domain
PMNHDPHM_00627 2.6e-135 M Glycosyltransferases, probably involved in cell wall biogenesis
PMNHDPHM_00628 4.4e-108 speG J Acetyltransferase (GNAT) domain
PMNHDPHM_00629 4.9e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
PMNHDPHM_00630 1.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_00631 6.9e-130 K UbiC transcription regulator-associated domain protein
PMNHDPHM_00632 2e-239 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_00633 1.2e-73 S Domain of unknown function (DUF3284)
PMNHDPHM_00634 2.2e-215 S Bacterial protein of unknown function (DUF871)
PMNHDPHM_00635 4.8e-268 argH 4.3.2.1 E argininosuccinate lyase
PMNHDPHM_00636 1e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PMNHDPHM_00637 9.3e-259 arpJ P ABC transporter permease
PMNHDPHM_00638 1.8e-124 S Alpha/beta hydrolase family
PMNHDPHM_00639 8.1e-131 K response regulator
PMNHDPHM_00640 0.0 vicK 2.7.13.3 T Histidine kinase
PMNHDPHM_00641 1.3e-260 yycH S YycH protein
PMNHDPHM_00642 1.1e-141 yycI S YycH protein
PMNHDPHM_00643 2.7e-154 vicX 3.1.26.11 S domain protein
PMNHDPHM_00644 2e-10
PMNHDPHM_00645 2.9e-206 htrA 3.4.21.107 O serine protease
PMNHDPHM_00646 1.2e-70 S Iron-sulphur cluster biosynthesis
PMNHDPHM_00647 3.2e-77 hsp3 O Hsp20/alpha crystallin family
PMNHDPHM_00648 0.0 cadA P P-type ATPase
PMNHDPHM_00649 5.7e-145
PMNHDPHM_00651 3.4e-302 E ABC transporter, substratebinding protein
PMNHDPHM_00652 8e-257 E Peptidase dimerisation domain
PMNHDPHM_00653 2.3e-103
PMNHDPHM_00654 4.8e-199 ybiR P Citrate transporter
PMNHDPHM_00655 1.6e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PMNHDPHM_00656 5e-70 6.3.3.2 S ASCH
PMNHDPHM_00657 3.1e-124
PMNHDPHM_00658 1.1e-86 K Acetyltransferase (GNAT) domain
PMNHDPHM_00659 6.8e-136 wzb 3.1.3.48 T Tyrosine phosphatase family
PMNHDPHM_00660 2.8e-90 MA20_25245 K FR47-like protein
PMNHDPHM_00661 2.4e-110 S alpha beta
PMNHDPHM_00662 1.2e-36
PMNHDPHM_00663 3.1e-61
PMNHDPHM_00666 1.7e-51 sugE U Multidrug resistance protein
PMNHDPHM_00667 1e-173 draG 3.2.2.24 O ADP-ribosylglycohydrolase
PMNHDPHM_00668 6.1e-145 Q Methyltransferase
PMNHDPHM_00669 1.3e-75 adhR K helix_turn_helix, mercury resistance
PMNHDPHM_00670 4.5e-160 1.1.1.346 S reductase
PMNHDPHM_00671 2e-174 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PMNHDPHM_00672 2.4e-203 S endonuclease exonuclease phosphatase family protein
PMNHDPHM_00674 3.3e-131 G PTS system sorbose-specific iic component
PMNHDPHM_00675 4.9e-151 G PTS system mannose/fructose/sorbose family IID component
PMNHDPHM_00676 1.5e-80 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_00677 6.7e-165 ybbH_2 K Helix-turn-helix domain, rpiR family
PMNHDPHM_00678 3.3e-150 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PMNHDPHM_00679 1.7e-198 blaA6 V Beta-lactamase
PMNHDPHM_00680 8.6e-150 3.5.2.6 V Beta-lactamase enzyme family
PMNHDPHM_00681 3.2e-226 EGP Major facilitator Superfamily
PMNHDPHM_00682 2.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
PMNHDPHM_00683 6.6e-165 ugpA P ABC-type sugar transport systems, permease components
PMNHDPHM_00684 2.2e-148 ugpE G ABC transporter permease
PMNHDPHM_00685 2.9e-241 ugpB G Bacterial extracellular solute-binding protein
PMNHDPHM_00686 9.3e-71 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PMNHDPHM_00687 3.2e-132 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
PMNHDPHM_00688 1.1e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMNHDPHM_00689 4.5e-108 pncA Q Isochorismatase family
PMNHDPHM_00690 1.5e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
PMNHDPHM_00691 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
PMNHDPHM_00692 8.6e-99 K Helix-turn-helix domain
PMNHDPHM_00694 1.4e-113 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
PMNHDPHM_00695 3.1e-92 yjgM K Acetyltransferase (GNAT) domain
PMNHDPHM_00696 2.4e-133 farR K Helix-turn-helix domain
PMNHDPHM_00697 6.9e-161 gatY G Fructose-bisphosphate aldolase class-II
PMNHDPHM_00698 9.9e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_00699 1.6e-48 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_00700 4.7e-252 gatC G PTS system sugar-specific permease component
PMNHDPHM_00701 5.7e-280 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
PMNHDPHM_00702 3.7e-162 G Fructose-bisphosphate aldolase class-II
PMNHDPHM_00703 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
PMNHDPHM_00704 8.7e-122 gluP 3.4.21.105 S Peptidase, S54 family
PMNHDPHM_00705 1.1e-40 yqgQ S Bacterial protein of unknown function (DUF910)
PMNHDPHM_00706 2.4e-178 glk 2.7.1.2 G Glucokinase
PMNHDPHM_00707 3.7e-72 yqhL P Rhodanese-like protein
PMNHDPHM_00708 4.4e-25 WQ51_02665 S Protein of unknown function (DUF3042)
PMNHDPHM_00709 4.7e-182 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PMNHDPHM_00710 5.3e-242 ynbB 4.4.1.1 P aluminum resistance
PMNHDPHM_00711 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
PMNHDPHM_00712 1e-60 glnR K Transcriptional regulator
PMNHDPHM_00713 5.8e-263 glnA 6.3.1.2 E glutamine synthetase
PMNHDPHM_00714 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PMNHDPHM_00715 1.5e-300 V ABC transporter transmembrane region
PMNHDPHM_00717 3.9e-234 ywhK S Membrane
PMNHDPHM_00718 4.1e-14
PMNHDPHM_00719 1.3e-32
PMNHDPHM_00720 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PMNHDPHM_00721 3.2e-56 ysxB J Cysteine protease Prp
PMNHDPHM_00722 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PMNHDPHM_00723 8.3e-204 ypdF 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMNHDPHM_00724 6.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMNHDPHM_00725 2e-77 yqhY S Asp23 family, cell envelope-related function
PMNHDPHM_00726 2e-66 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMNHDPHM_00727 5e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMNHDPHM_00728 1e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMNHDPHM_00729 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMNHDPHM_00730 9.4e-150 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMNHDPHM_00731 3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PMNHDPHM_00732 2e-74 argR K Regulates arginine biosynthesis genes
PMNHDPHM_00733 6.1e-310 recN L May be involved in recombinational repair of damaged DNA
PMNHDPHM_00734 6e-51
PMNHDPHM_00735 2.1e-123 rssA S Patatin-like phospholipase
PMNHDPHM_00736 3.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PMNHDPHM_00737 2.9e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PMNHDPHM_00738 7.3e-217 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PMNHDPHM_00739 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMNHDPHM_00740 6.5e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMNHDPHM_00741 5.4e-253 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PMNHDPHM_00742 1.5e-135 stp 3.1.3.16 T phosphatase
PMNHDPHM_00743 0.0 KLT serine threonine protein kinase
PMNHDPHM_00744 6e-171 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PMNHDPHM_00745 1.5e-115 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PMNHDPHM_00746 6.7e-127 thiN 2.7.6.2 H thiamine pyrophosphokinase
PMNHDPHM_00747 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PMNHDPHM_00748 2.3e-57 asp S Asp23 family, cell envelope-related function
PMNHDPHM_00749 1.3e-309 yloV S DAK2 domain fusion protein YloV
PMNHDPHM_00750 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PMNHDPHM_00751 1e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PMNHDPHM_00752 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMNHDPHM_00753 4.4e-194 oppD P Belongs to the ABC transporter superfamily
PMNHDPHM_00754 1.4e-178 oppF P Belongs to the ABC transporter superfamily
PMNHDPHM_00755 2.8e-174 oppB P ABC transporter permease
PMNHDPHM_00756 8.2e-136 oppC EP Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00757 0.0 oppA1 E ABC transporter substrate-binding protein
PMNHDPHM_00758 7.7e-126 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PMNHDPHM_00759 0.0 smc D Required for chromosome condensation and partitioning
PMNHDPHM_00760 5.7e-183 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PMNHDPHM_00761 8.8e-53
PMNHDPHM_00762 5.6e-26
PMNHDPHM_00763 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PMNHDPHM_00764 3.1e-230 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMNHDPHM_00765 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PMNHDPHM_00766 8.4e-38 ylqC S Belongs to the UPF0109 family
PMNHDPHM_00767 7.6e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PMNHDPHM_00768 1.6e-148 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PMNHDPHM_00769 6.5e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PMNHDPHM_00770 1.1e-25
PMNHDPHM_00771 1.1e-37 ynzC S UPF0291 protein
PMNHDPHM_00772 4.8e-29 yneF S UPF0154 protein
PMNHDPHM_00773 0.0 mdlA V ABC transporter
PMNHDPHM_00774 0.0 mdlB V ABC transporter
PMNHDPHM_00775 2.6e-138 yejC S Protein of unknown function (DUF1003)
PMNHDPHM_00776 9.1e-203 bcaP E Amino Acid
PMNHDPHM_00777 1.5e-123 plsC 2.3.1.51 I Acyltransferase
PMNHDPHM_00778 4.8e-134 yabB 2.1.1.223 L Methyltransferase small domain
PMNHDPHM_00779 1.3e-47 yazA L GIY-YIG catalytic domain protein
PMNHDPHM_00780 1.8e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
PMNHDPHM_00781 2e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PMNHDPHM_00782 1e-257 wcaJ M Bacterial sugar transferase
PMNHDPHM_00783 5.4e-175 cps2D 5.1.3.2 M RmlD substrate binding domain
PMNHDPHM_00784 1.1e-110 glnP P ABC transporter permease
PMNHDPHM_00785 7.9e-109 gluC P ABC transporter permease
PMNHDPHM_00786 3.4e-149 glnH ET ABC transporter substrate-binding protein
PMNHDPHM_00787 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMNHDPHM_00788 3.4e-172
PMNHDPHM_00790 5.6e-85 zur P Belongs to the Fur family
PMNHDPHM_00791 8.2e-09
PMNHDPHM_00792 9.3e-112 gmk2 2.7.4.8 F Guanylate kinase
PMNHDPHM_00793 6e-70 K Acetyltransferase (GNAT) domain
PMNHDPHM_00794 1e-125 spl M NlpC/P60 family
PMNHDPHM_00795 7.5e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PMNHDPHM_00796 3.1e-15 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMNHDPHM_00797 3e-139 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMNHDPHM_00798 5e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
PMNHDPHM_00799 5.9e-174 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMNHDPHM_00800 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
PMNHDPHM_00801 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PMNHDPHM_00802 3.1e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
PMNHDPHM_00803 3.6e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
PMNHDPHM_00804 1.7e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PMNHDPHM_00805 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PMNHDPHM_00806 7.2e-205 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
PMNHDPHM_00807 2.5e-116 ylcC 3.4.22.70 M Sortase family
PMNHDPHM_00808 3e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMNHDPHM_00809 0.0 fbp 3.1.3.11 G phosphatase activity
PMNHDPHM_00813 1.3e-07
PMNHDPHM_00815 2.8e-09
PMNHDPHM_00817 6.4e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
PMNHDPHM_00818 7.6e-45 S Bacterial toxin of type II toxin-antitoxin system, YafQ
PMNHDPHM_00819 5.1e-153 S hydrolase
PMNHDPHM_00820 1.3e-262 npr 1.11.1.1 C NADH oxidase
PMNHDPHM_00821 4.3e-121 devA 3.6.3.25 V ABC transporter, ATP-binding protein
PMNHDPHM_00822 1e-185 hrtB V ABC transporter permease
PMNHDPHM_00823 1e-87 ygfC K Bacterial regulatory proteins, tetR family
PMNHDPHM_00824 2.4e-30 S response to antibiotic
PMNHDPHM_00825 8.7e-147 yqfZ 3.2.1.17 M hydrolase, family 25
PMNHDPHM_00826 1.3e-17 S YvrJ protein family
PMNHDPHM_00827 2.3e-08 K DNA-templated transcription, initiation
PMNHDPHM_00828 9.8e-07
PMNHDPHM_00829 6.7e-128
PMNHDPHM_00830 1.6e-120 P Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00831 3.4e-115 P Binding-protein-dependent transport system inner membrane component
PMNHDPHM_00832 3.4e-163 ET Bacterial periplasmic substrate-binding proteins
PMNHDPHM_00833 5.4e-133 E ABC transporter
PMNHDPHM_00834 2.5e-200 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
PMNHDPHM_00835 3.2e-275 abgB 3.5.1.47 S Peptidase dimerisation domain
PMNHDPHM_00836 2.1e-211 G Major Facilitator Superfamily
PMNHDPHM_00837 0.0 GK helix_turn_helix, arabinose operon control protein
PMNHDPHM_00838 2.5e-163 K helix_turn_helix, arabinose operon control protein
PMNHDPHM_00839 2.8e-263 lysP E amino acid
PMNHDPHM_00840 2e-277 ygjI E Amino Acid
PMNHDPHM_00841 0.0 ebgA 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
PMNHDPHM_00842 1.3e-42 K Transcriptional regulator, LysR family
PMNHDPHM_00843 1e-75 K DNA-binding transcription factor activity
PMNHDPHM_00844 1.1e-242 E Peptidase family M20/M25/M40
PMNHDPHM_00845 6.8e-28
PMNHDPHM_00846 8.6e-292 2.4.1.52 GT4 M Glycosyl transferases group 1
PMNHDPHM_00847 2.1e-304 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PMNHDPHM_00848 7.7e-263 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
PMNHDPHM_00849 9.7e-100 yqaB S Acetyltransferase (GNAT) domain
PMNHDPHM_00850 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PMNHDPHM_00851 4.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMNHDPHM_00852 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PMNHDPHM_00853 7.4e-172 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMNHDPHM_00854 0.0 asnB 6.3.5.4 E Asparagine synthase
PMNHDPHM_00855 7e-138 3.5.1.124 S DJ-1/PfpI family
PMNHDPHM_00856 3.1e-80 yosT L Bacterial transcription activator, effector binding domain
PMNHDPHM_00857 7.2e-208 S Calcineurin-like phosphoesterase
PMNHDPHM_00858 5.1e-162 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
PMNHDPHM_00859 1.3e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PMNHDPHM_00860 1.2e-222 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMNHDPHM_00861 8.8e-167 natA S ABC transporter
PMNHDPHM_00862 2.9e-211 ysdA CP ABC-2 family transporter protein
PMNHDPHM_00863 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
PMNHDPHM_00864 8.9e-164 CcmA V ABC transporter
PMNHDPHM_00865 1.5e-115 VPA0052 I ABC-2 family transporter protein
PMNHDPHM_00866 3.1e-147 IQ reductase
PMNHDPHM_00867 1.3e-187 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_00868 1e-92 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_00869 0.0 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMNHDPHM_00870 1.7e-159 licT K CAT RNA binding domain
PMNHDPHM_00871 1e-298 cydC V ABC transporter transmembrane region
PMNHDPHM_00872 0.0 cydD CO ABC transporter transmembrane region
PMNHDPHM_00873 7.6e-76 ynhH S NusG domain II
PMNHDPHM_00874 8.3e-175 M Peptidoglycan-binding domain 1 protein
PMNHDPHM_00875 4e-25 XK27_02675 K Acetyltransferase (GNAT) domain
PMNHDPHM_00877 5.8e-118 S CRISPR-associated protein (Cas_Csn2)
PMNHDPHM_00878 7.5e-49 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PMNHDPHM_00879 1.1e-170 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PMNHDPHM_00880 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PMNHDPHM_00881 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
PMNHDPHM_00882 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
PMNHDPHM_00883 1.5e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
PMNHDPHM_00884 1.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
PMNHDPHM_00885 3e-240 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
PMNHDPHM_00886 2e-175 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PMNHDPHM_00887 4.6e-38
PMNHDPHM_00888 4.9e-87
PMNHDPHM_00889 2.7e-24
PMNHDPHM_00890 3.6e-163 yicL EG EamA-like transporter family
PMNHDPHM_00891 1.5e-112 tag 3.2.2.20 L glycosylase
PMNHDPHM_00892 1.1e-77 usp5 T universal stress protein
PMNHDPHM_00893 4.7e-64 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_00894 6.1e-244 gatC G PTS system sugar-specific permease component
PMNHDPHM_00895 1.1e-147 IQ KR domain
PMNHDPHM_00896 5.8e-177 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 F pfkB family carbohydrate kinase
PMNHDPHM_00897 7.1e-65 XK27_08465 2.7.1.191 G PTS system fructose IIA component
PMNHDPHM_00898 2.1e-146 manZ_1 G PTS system mannose/fructose/sorbose family IID component
PMNHDPHM_00899 1.6e-129 XK27_08455 G PTS system sorbose-specific iic component
PMNHDPHM_00900 8.1e-82 manX_1 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_00901 0.0 bgaC 3.2.1.23 G Glycosyl hydrolases family 35
PMNHDPHM_00902 2.9e-226 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMNHDPHM_00903 2e-219 agaS G SIS domain
PMNHDPHM_00904 9e-130 XK27_08435 K UTRA
PMNHDPHM_00905 3.7e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
PMNHDPHM_00906 2.6e-83
PMNHDPHM_00907 2.5e-239 malE G Bacterial extracellular solute-binding protein
PMNHDPHM_00908 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
PMNHDPHM_00909 4.7e-120
PMNHDPHM_00910 6.2e-162 sepS16B
PMNHDPHM_00911 1e-262 nox 1.6.3.4 C NADH oxidase
PMNHDPHM_00912 2e-70 p75 M NlpC P60 family protein
PMNHDPHM_00913 3.8e-145 ptp3 3.1.3.48 T Tyrosine phosphatase family
PMNHDPHM_00914 1.3e-223 queG 1.17.99.6 C Domain of unknown function (DUF1730)
PMNHDPHM_00915 8.3e-63
PMNHDPHM_00916 2.2e-88 bioY S BioY family
PMNHDPHM_00918 4.8e-102 Q methyltransferase
PMNHDPHM_00919 1.9e-101 T Sh3 type 3 domain protein
PMNHDPHM_00920 3.2e-115 yfeJ 6.3.5.2 F glutamine amidotransferase
PMNHDPHM_00921 1.6e-140 S Uncharacterized protein conserved in bacteria (DUF2263)
PMNHDPHM_00922 7.6e-258 yhdP S Transporter associated domain
PMNHDPHM_00923 1.9e-144 S Alpha beta hydrolase
PMNHDPHM_00924 7.8e-196 I Acyltransferase
PMNHDPHM_00925 2.4e-262 lmrB EGP Major facilitator Superfamily
PMNHDPHM_00926 5.2e-84 S Domain of unknown function (DUF4811)
PMNHDPHM_00927 1e-96 maf D nucleoside-triphosphate diphosphatase activity
PMNHDPHM_00928 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PMNHDPHM_00929 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PMNHDPHM_00930 0.0 ydaO E amino acid
PMNHDPHM_00931 1.1e-56 S Domain of unknown function (DUF1827)
PMNHDPHM_00932 4.5e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PMNHDPHM_00933 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMNHDPHM_00934 4.2e-110 ydiL S CAAX protease self-immunity
PMNHDPHM_00935 1.3e-196 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMNHDPHM_00936 3.7e-196
PMNHDPHM_00937 1.6e-160 ytrB V ABC transporter
PMNHDPHM_00938 1e-60 ytrA K helix_turn_helix gluconate operon transcriptional repressor
PMNHDPHM_00939 4.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PMNHDPHM_00940 0.0 uup S ABC transporter, ATP-binding protein
PMNHDPHM_00941 1.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_00942 1.8e-187 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PMNHDPHM_00943 6.2e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
PMNHDPHM_00944 3.1e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
PMNHDPHM_00945 1.9e-124
PMNHDPHM_00946 7.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
PMNHDPHM_00947 5.3e-181 ansA 3.5.1.1 EJ Asparaginase
PMNHDPHM_00948 1.1e-143 fat 3.1.2.21 I Acyl-ACP thioesterase
PMNHDPHM_00949 2.4e-153 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PMNHDPHM_00950 1.7e-57 yabA L Involved in initiation control of chromosome replication
PMNHDPHM_00951 4.3e-175 holB 2.7.7.7 L DNA polymerase III
PMNHDPHM_00952 7.8e-52 yaaQ S Cyclic-di-AMP receptor
PMNHDPHM_00953 7.4e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMNHDPHM_00954 8.7e-38 S Protein of unknown function (DUF2508)
PMNHDPHM_00955 5.6e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PMNHDPHM_00956 1.5e-33 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PMNHDPHM_00957 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PMNHDPHM_00958 7.2e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PMNHDPHM_00959 1.2e-49
PMNHDPHM_00960 9e-107 rsmC 2.1.1.172 J Methyltransferase
PMNHDPHM_00961 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PMNHDPHM_00962 2.3e-69
PMNHDPHM_00963 3.5e-174 ccpB 5.1.1.1 K lacI family
PMNHDPHM_00964 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
PMNHDPHM_00965 3.2e-156 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PMNHDPHM_00966 2.5e-51 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PMNHDPHM_00967 7.7e-83 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PMNHDPHM_00968 9.8e-225 mdtG EGP Major facilitator Superfamily
PMNHDPHM_00969 1.7e-156 K acetyltransferase
PMNHDPHM_00970 3.1e-90
PMNHDPHM_00971 1.6e-222 yceI G Sugar (and other) transporter
PMNHDPHM_00972 7e-30
PMNHDPHM_00973 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PMNHDPHM_00974 1.5e-124
PMNHDPHM_00975 5.8e-67 S Protein of unknown function (DUF1093)
PMNHDPHM_00976 6.4e-215 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
PMNHDPHM_00977 1.3e-193 rhaR K helix_turn_helix, arabinose operon control protein
PMNHDPHM_00978 1.8e-227 iolF EGP Major facilitator Superfamily
PMNHDPHM_00979 2e-285 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 F Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
PMNHDPHM_00980 1.3e-56 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
PMNHDPHM_00981 1.4e-258 rhaA 2.7.1.5, 5.3.1.14 G L-rhamnose isomerase (RhaA)
PMNHDPHM_00982 8e-168 rhaD 4.1.2.17, 4.1.2.19 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PMNHDPHM_00983 0.0 fucI 5.3.1.25, 5.3.1.3 G Converts the aldose L-fucose into the corresponding ketose L-fuculose
PMNHDPHM_00984 8.5e-295 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 2.7.1.51 G FGGY family of carbohydrate kinases, N-terminal domain
PMNHDPHM_00985 1.8e-232 ywtG EGP Major facilitator Superfamily
PMNHDPHM_00986 6.4e-78 fucU 5.1.3.29 G RbsD / FucU transport protein family
PMNHDPHM_00987 3.4e-146 4.1.2.17, 4.1.2.19, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
PMNHDPHM_00988 1.1e-133 fcsR K DeoR C terminal sensor domain
PMNHDPHM_00989 5e-136 K UbiC transcription regulator-associated domain protein
PMNHDPHM_00990 2.8e-233 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_00991 3e-87 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_00992 1.5e-46 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_00993 5.7e-163
PMNHDPHM_00994 1.4e-297 2.4.1.52 GT4 M Glycosyl transferases group 1
PMNHDPHM_00995 0.0 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PMNHDPHM_00996 2.2e-219 S Uncharacterized protein conserved in bacteria (DUF2325)
PMNHDPHM_00997 6.6e-234 4.4.1.8 E Aminotransferase, class I
PMNHDPHM_00998 4.1e-203 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMNHDPHM_00999 3.1e-253 2.7.1.207 U The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_01000 1.8e-59 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_01001 3.8e-48 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_01002 2.5e-197 ypdE E M42 glutamyl aminopeptidase
PMNHDPHM_01003 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01004 1.6e-238 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PMNHDPHM_01005 3.4e-297 E ABC transporter, substratebinding protein
PMNHDPHM_01006 1.1e-121 S Acetyltransferase (GNAT) family
PMNHDPHM_01008 0.0 nisT V ABC transporter
PMNHDPHM_01009 2.6e-95 S ABC-type cobalt transport system, permease component
PMNHDPHM_01010 2.2e-246 P ABC transporter
PMNHDPHM_01011 5.3e-113 P cobalt transport
PMNHDPHM_01012 2.4e-127 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PMNHDPHM_01013 1.1e-81 thiW S Thiamine-precursor transporter protein (ThiW)
PMNHDPHM_01014 1.9e-150 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PMNHDPHM_01015 7.5e-104 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PMNHDPHM_01016 2.8e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PMNHDPHM_01017 1.1e-272 E Amino acid permease
PMNHDPHM_01018 1e-187 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
PMNHDPHM_01020 1.6e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMNHDPHM_01021 9.3e-44 K DNA-binding helix-turn-helix protein
PMNHDPHM_01022 1.7e-36
PMNHDPHM_01023 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
PMNHDPHM_01024 3.6e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PMNHDPHM_01025 6e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PMNHDPHM_01026 1.2e-233 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_01027 1.4e-167 S Alpha/beta hydrolase of unknown function (DUF915)
PMNHDPHM_01028 3.7e-54 yvdC S MazG nucleotide pyrophosphohydrolase domain
PMNHDPHM_01029 1.1e-124 livF E ABC transporter
PMNHDPHM_01030 2.1e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
PMNHDPHM_01031 1.7e-120 livM E Branched-chain amino acid transport system / permease component
PMNHDPHM_01032 6.7e-151 livH U Branched-chain amino acid transport system / permease component
PMNHDPHM_01033 4.4e-214 livJ E Receptor family ligand binding region
PMNHDPHM_01034 3.5e-74 S Threonine/Serine exporter, ThrE
PMNHDPHM_01035 6.6e-134 thrE S Putative threonine/serine exporter
PMNHDPHM_01036 1.7e-43 trxC O Belongs to the thioredoxin family
PMNHDPHM_01037 9.4e-71 ahaA 2.7.1.191 G PTS system fructose IIA component
PMNHDPHM_01038 8.5e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_01039 3.7e-137 G PTS system sorbose-specific iic component
PMNHDPHM_01040 1.3e-151 manZ G PTS system mannose/fructose/sorbose family IID component
PMNHDPHM_01041 1.2e-204 C Zinc-binding dehydrogenase
PMNHDPHM_01042 1.5e-288 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PMNHDPHM_01043 2.7e-97 S Domain of unknown function (DUF4428)
PMNHDPHM_01044 1.4e-208 3.2.1.51 GH29 G Alpha-L-fucosidase
PMNHDPHM_01045 5.3e-215 uhpT EGP Major facilitator Superfamily
PMNHDPHM_01046 2.2e-131 ymfC K UTRA
PMNHDPHM_01047 5.2e-256 3.5.1.18 E Peptidase family M20/M25/M40
PMNHDPHM_01048 1.4e-181 aspG 3.4.19.5, 3.5.1.1, 3.5.1.26 E Asparaginase
PMNHDPHM_01049 1e-159 bglK_1 GK ROK family
PMNHDPHM_01050 1.7e-44
PMNHDPHM_01051 0.0 O Belongs to the peptidase S8 family
PMNHDPHM_01052 4.7e-215 ulaG S Beta-lactamase superfamily domain
PMNHDPHM_01053 3.8e-81 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01054 5.3e-281 ulaA S PTS system sugar-specific permease component
PMNHDPHM_01055 3.7e-45 sgaB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_01056 7.4e-115 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
PMNHDPHM_01057 1.3e-137 repA K DeoR C terminal sensor domain
PMNHDPHM_01058 1.2e-168 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
PMNHDPHM_01059 4.1e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
PMNHDPHM_01060 1.6e-137 araD 4.1.2.17, 4.1.2.19, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
PMNHDPHM_01061 2.2e-145 IQ NAD dependent epimerase/dehydratase family
PMNHDPHM_01062 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
PMNHDPHM_01063 1.2e-88 gutM K Glucitol operon activator protein (GutM)
PMNHDPHM_01064 2.2e-102 srlA G PTS system enzyme II sorbitol-specific factor
PMNHDPHM_01065 1.1e-195 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
PMNHDPHM_01066 4.1e-65 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PMNHDPHM_01067 4.5e-123 tal 2.2.1.2 H Pfam:Transaldolase
PMNHDPHM_01068 0.0 K Mga helix-turn-helix domain
PMNHDPHM_01069 3.6e-55 S PRD domain
PMNHDPHM_01070 1.2e-61 S Glycine-rich SFCGS
PMNHDPHM_01071 6e-53 S Domain of unknown function (DUF4312)
PMNHDPHM_01072 1.7e-137 S Domain of unknown function (DUF4311)
PMNHDPHM_01073 3.6e-107 S Domain of unknown function (DUF4310)
PMNHDPHM_01074 2e-216 dho 3.5.2.3 S Amidohydrolase family
PMNHDPHM_01075 9.1e-206 selA 2.9.1.1 H L-seryl-tRNA selenium transferase
PMNHDPHM_01076 9.6e-138 4.1.2.14 S KDGP aldolase
PMNHDPHM_01078 1.9e-83 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
PMNHDPHM_01079 2.3e-131 K Helix-turn-helix domain, rpiR family
PMNHDPHM_01081 1.3e-298 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
PMNHDPHM_01082 2.9e-273 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
PMNHDPHM_01083 9.5e-49
PMNHDPHM_01084 7.6e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PMNHDPHM_01085 7e-153 metQ_4 P Belongs to the nlpA lipoprotein family
PMNHDPHM_01086 1.1e-197 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
PMNHDPHM_01087 2.5e-175
PMNHDPHM_01088 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
PMNHDPHM_01089 9.4e-17
PMNHDPHM_01090 4e-104 K Bacterial regulatory proteins, tetR family
PMNHDPHM_01091 9.6e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
PMNHDPHM_01092 3.4e-103 dhaL 2.7.1.121 S Dak2
PMNHDPHM_01093 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
PMNHDPHM_01094 2.4e-77 ohr O OsmC-like protein
PMNHDPHM_01095 1.9e-121 V ATPases associated with a variety of cellular activities
PMNHDPHM_01096 2e-206
PMNHDPHM_01097 1.6e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
PMNHDPHM_01098 3.4e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PMNHDPHM_01099 9.2e-214 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMNHDPHM_01100 8e-134 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PMNHDPHM_01101 7.5e-42 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMNHDPHM_01102 3e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMNHDPHM_01103 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PMNHDPHM_01104 8.2e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PMNHDPHM_01105 1.3e-187 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PMNHDPHM_01106 2e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PMNHDPHM_01107 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PMNHDPHM_01108 1.3e-221 purD 6.3.4.13 F Belongs to the GARS family
PMNHDPHM_01109 2.5e-77 copR K Copper transport repressor CopY TcrY
PMNHDPHM_01110 0.0 copB 3.6.3.4 P P-type ATPase
PMNHDPHM_01111 1.1e-109 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMNHDPHM_01112 4e-209 T PhoQ Sensor
PMNHDPHM_01113 1e-122 K response regulator
PMNHDPHM_01114 2.6e-138 bceA V ABC transporter
PMNHDPHM_01115 0.0 V ABC transporter (permease)
PMNHDPHM_01116 3.4e-91 traP 1.14.99.57, 6.2.1.3 S Antibiotic biosynthesis monooxygenase
PMNHDPHM_01117 9.9e-140 yhfI S Metallo-beta-lactamase superfamily
PMNHDPHM_01118 1.9e-80 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PMNHDPHM_01119 5.1e-122 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PMNHDPHM_01120 6.1e-308 glpQ 3.1.4.46 C phosphodiesterase
PMNHDPHM_01121 1.2e-177 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PMNHDPHM_01122 2.7e-22
PMNHDPHM_01123 1.2e-67
PMNHDPHM_01125 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PMNHDPHM_01126 5.3e-75 argR K Regulates arginine biosynthesis genes
PMNHDPHM_01127 4.5e-157 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMNHDPHM_01128 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PMNHDPHM_01129 4.6e-55 yheA S Control of competence regulator ComK, YlbF/YmcA
PMNHDPHM_01130 9.6e-183 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMNHDPHM_01131 2.6e-158 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
PMNHDPHM_01132 7.4e-48 yhaH S YtxH-like protein
PMNHDPHM_01133 1.3e-75 hit FG histidine triad
PMNHDPHM_01134 3.4e-132 ecsA V ABC transporter, ATP-binding protein
PMNHDPHM_01135 7.4e-225 ecsB U ABC transporter
PMNHDPHM_01136 1.2e-148 ytmP 2.7.1.89 M Choline/ethanolamine kinase
PMNHDPHM_01137 4.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PMNHDPHM_01139 7.2e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PMNHDPHM_01140 3.6e-114 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMNHDPHM_01142 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
PMNHDPHM_01143 4.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PMNHDPHM_01144 2.7e-269 K Mga helix-turn-helix domain
PMNHDPHM_01145 0.0 N domain, Protein
PMNHDPHM_01146 4.3e-141 S WxL domain surface cell wall-binding
PMNHDPHM_01148 4.8e-196 S Cell surface protein
PMNHDPHM_01150 3.2e-119 ybhL S Inhibitor of apoptosis-promoting Bax1
PMNHDPHM_01151 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMNHDPHM_01152 9e-161 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PMNHDPHM_01153 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PMNHDPHM_01154 3.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMNHDPHM_01155 9.3e-253 dnaB L replication initiation and membrane attachment
PMNHDPHM_01156 1.2e-169 dnaI L Primosomal protein DnaI
PMNHDPHM_01157 5.3e-228 V regulation of methylation-dependent chromatin silencing
PMNHDPHM_01158 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMNHDPHM_01159 1.9e-65
PMNHDPHM_01160 1.3e-128 S SseB protein N-terminal domain
PMNHDPHM_01161 3.4e-137 cobB K Sir2 family
PMNHDPHM_01162 1.8e-235 EGP Major Facilitator Superfamily
PMNHDPHM_01163 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PMNHDPHM_01164 3.3e-56
PMNHDPHM_01165 1.3e-177 S Cell surface protein
PMNHDPHM_01166 1.3e-114 S WxL domain surface cell wall-binding
PMNHDPHM_01167 5.1e-254 brnQ U Component of the transport system for branched-chain amino acids
PMNHDPHM_01168 7.2e-124
PMNHDPHM_01169 5.9e-121 tcyB E ABC transporter
PMNHDPHM_01170 8.6e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
PMNHDPHM_01171 2.5e-214 metC 4.4.1.8 E cystathionine
PMNHDPHM_01173 2.4e-144
PMNHDPHM_01175 2.7e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PMNHDPHM_01176 6.1e-162 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
PMNHDPHM_01177 8.2e-168 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMNHDPHM_01178 1.1e-217 ydiN EGP Major Facilitator Superfamily
PMNHDPHM_01180 1.3e-159 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PMNHDPHM_01181 7.2e-155 IQ Enoyl-(Acyl carrier protein) reductase
PMNHDPHM_01182 2.3e-167 G Xylose isomerase-like TIM barrel
PMNHDPHM_01183 4e-167 K Transcriptional regulator, LysR family
PMNHDPHM_01184 2.8e-93 S Protein of unknown function (DUF1440)
PMNHDPHM_01185 2.9e-246 G MFS/sugar transport protein
PMNHDPHM_01186 3.4e-277 ycaM E amino acid
PMNHDPHM_01187 0.0 pepN 3.4.11.2 E aminopeptidase
PMNHDPHM_01188 1.2e-08
PMNHDPHM_01189 8.6e-108
PMNHDPHM_01190 4.3e-203
PMNHDPHM_01191 4.6e-163 V ATPases associated with a variety of cellular activities
PMNHDPHM_01192 1.2e-197 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
PMNHDPHM_01193 6.8e-127 K Transcriptional regulatory protein, C terminal
PMNHDPHM_01194 2.9e-301 S Psort location CytoplasmicMembrane, score
PMNHDPHM_01195 3.2e-130 XK27_12140 V ATPases associated with a variety of cellular activities
PMNHDPHM_01196 6.8e-204
PMNHDPHM_01197 8e-129 S membrane transporter protein
PMNHDPHM_01198 4e-59 hxlR K Transcriptional regulator, HxlR family
PMNHDPHM_01199 1.9e-197 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PMNHDPHM_01200 2.6e-163 morA2 S reductase
PMNHDPHM_01201 1e-75 K helix_turn_helix, mercury resistance
PMNHDPHM_01203 2.4e-248 E Amino acid permease
PMNHDPHM_01204 3.7e-226 S Amidohydrolase
PMNHDPHM_01205 5.1e-259 6.3.1.2 E Glutamine synthetase N-terminal domain
PMNHDPHM_01207 5.7e-143 puuD S peptidase C26
PMNHDPHM_01209 2.4e-141 H Protein of unknown function (DUF1698)
PMNHDPHM_01210 1.6e-194 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
PMNHDPHM_01211 4e-104 V Beta-lactamase
PMNHDPHM_01212 1.1e-70 ampH V Beta-lactamase
PMNHDPHM_01213 1.2e-45
PMNHDPHM_01214 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMNHDPHM_01215 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
PMNHDPHM_01216 1.1e-33
PMNHDPHM_01217 3e-107 tag 3.2.2.20 L glycosylase
PMNHDPHM_01218 9.6e-206 yceJ EGP Major facilitator Superfamily
PMNHDPHM_01219 1.2e-48 K Helix-turn-helix domain
PMNHDPHM_01220 2.9e-44 relB L RelB antitoxin
PMNHDPHM_01221 3e-262 L Exonuclease
PMNHDPHM_01228 3.6e-79 ctsR K Belongs to the CtsR family
PMNHDPHM_01229 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMNHDPHM_01230 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMNHDPHM_01231 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMNHDPHM_01232 4e-84 3.4.23.43
PMNHDPHM_01233 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PMNHDPHM_01234 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PMNHDPHM_01235 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PMNHDPHM_01236 5.9e-199 yfjR K WYL domain
PMNHDPHM_01237 1.7e-107 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
PMNHDPHM_01238 1.2e-68 psiE S Phosphate-starvation-inducible E
PMNHDPHM_01239 1.2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
PMNHDPHM_01240 3e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PMNHDPHM_01241 3.4e-109 rplD J Forms part of the polypeptide exit tunnel
PMNHDPHM_01242 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PMNHDPHM_01243 3.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMNHDPHM_01244 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMNHDPHM_01245 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMNHDPHM_01246 3.7e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PMNHDPHM_01247 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PMNHDPHM_01248 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
PMNHDPHM_01249 1.4e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMNHDPHM_01250 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMNHDPHM_01251 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PMNHDPHM_01252 1.1e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PMNHDPHM_01253 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PMNHDPHM_01254 2.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PMNHDPHM_01255 4.6e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMNHDPHM_01256 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PMNHDPHM_01257 1.7e-24 rpmD J Ribosomal protein L30
PMNHDPHM_01258 2.2e-62 rplO J Binds to the 23S rRNA
PMNHDPHM_01259 7.5e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PMNHDPHM_01260 1.4e-121 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PMNHDPHM_01261 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMNHDPHM_01262 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PMNHDPHM_01263 2.1e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PMNHDPHM_01264 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PMNHDPHM_01265 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMNHDPHM_01266 3.1e-60 rplQ J Ribosomal protein L17
PMNHDPHM_01267 2.5e-121
PMNHDPHM_01268 4.3e-155 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMNHDPHM_01269 3.2e-158 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMNHDPHM_01270 1.6e-143 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PMNHDPHM_01271 1.1e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PMNHDPHM_01272 9.6e-138 tipA K TipAS antibiotic-recognition domain
PMNHDPHM_01273 6.4e-34
PMNHDPHM_01274 1.7e-128 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
PMNHDPHM_01275 2.9e-185 yxeA V FtsX-like permease family
PMNHDPHM_01276 1.9e-104 K Bacterial regulatory proteins, tetR family
PMNHDPHM_01277 7e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMNHDPHM_01278 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
PMNHDPHM_01279 4.5e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PMNHDPHM_01280 4.7e-165 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
PMNHDPHM_01281 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PMNHDPHM_01283 0.0 XK27_09600 V ABC transporter, ATP-binding protein
PMNHDPHM_01284 0.0 V ABC transporter
PMNHDPHM_01285 3.2e-220 oxlT P Major Facilitator Superfamily
PMNHDPHM_01286 2.2e-128 treR K UTRA
PMNHDPHM_01287 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
PMNHDPHM_01288 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMNHDPHM_01289 2.8e-214 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PMNHDPHM_01290 1.2e-269 yfnA E Amino Acid
PMNHDPHM_01291 5.1e-173 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
PMNHDPHM_01292 1.3e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PMNHDPHM_01293 4.6e-31 K 'Cold-shock' DNA-binding domain
PMNHDPHM_01294 2.3e-72
PMNHDPHM_01295 3.5e-76 O OsmC-like protein
PMNHDPHM_01296 1.2e-285 lsa S ABC transporter
PMNHDPHM_01297 1.7e-39
PMNHDPHM_01298 1.5e-83 usp6 T universal stress protein
PMNHDPHM_01299 4.4e-158 2.3.1.19 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_01300 4e-181 S Protein of unknown function (DUF2785)
PMNHDPHM_01301 4.9e-66 yueI S Protein of unknown function (DUF1694)
PMNHDPHM_01302 1.8e-26
PMNHDPHM_01303 5.6e-280 sufB O assembly protein SufB
PMNHDPHM_01304 2.9e-78 nifU C SUF system FeS assembly protein, NifU family
PMNHDPHM_01305 1.2e-227 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PMNHDPHM_01306 4.1e-192 sufD O FeS assembly protein SufD
PMNHDPHM_01307 5e-142 sufC O FeS assembly ATPase SufC
PMNHDPHM_01308 8.8e-106 metI P ABC transporter permease
PMNHDPHM_01309 2.4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMNHDPHM_01310 7.7e-149 P Belongs to the nlpA lipoprotein family
PMNHDPHM_01311 8.5e-148 P Belongs to the nlpA lipoprotein family
PMNHDPHM_01312 1.4e-214 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMNHDPHM_01313 1.6e-48 gcvH E glycine cleavage
PMNHDPHM_01314 5.8e-222 rodA D Belongs to the SEDS family
PMNHDPHM_01315 1.3e-31 S Protein of unknown function (DUF2969)
PMNHDPHM_01316 2.4e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
PMNHDPHM_01317 1.4e-25 epuA S DNA-directed RNA polymerase subunit beta
PMNHDPHM_01318 4.5e-180 mbl D Cell shape determining protein MreB Mrl
PMNHDPHM_01319 6.4e-32 ywzB S Protein of unknown function (DUF1146)
PMNHDPHM_01320 6.3e-215 lsgC M Glycosyl transferases group 1
PMNHDPHM_01321 0.0 yebA E Transglutaminase/protease-like homologues
PMNHDPHM_01322 1.2e-158 yeaD S Protein of unknown function DUF58
PMNHDPHM_01323 1.5e-169 yeaC S ATPase family associated with various cellular activities (AAA)
PMNHDPHM_01324 6.7e-105 S Stage II sporulation protein M
PMNHDPHM_01325 4e-101 ydaF J Acetyltransferase (GNAT) domain
PMNHDPHM_01326 4.7e-266 glnP P ABC transporter
PMNHDPHM_01327 6.5e-257 glnP P ABC transporter
PMNHDPHM_01328 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMNHDPHM_01329 2.4e-169 yniA G Phosphotransferase enzyme family
PMNHDPHM_01330 3.7e-145 S AAA ATPase domain
PMNHDPHM_01331 1.3e-287 ydbT S Bacterial PH domain
PMNHDPHM_01332 8.7e-81 S Bacterial PH domain
PMNHDPHM_01333 1.2e-52
PMNHDPHM_01334 1.5e-58 yqkB S Iron-sulphur cluster biosynthesis
PMNHDPHM_01335 5.1e-133 S Protein of unknown function (DUF975)
PMNHDPHM_01336 5.6e-239 malE G Bacterial extracellular solute-binding protein
PMNHDPHM_01337 2e-40
PMNHDPHM_01338 2.4e-133 glnQ E ABC transporter, ATP-binding protein
PMNHDPHM_01339 4e-287 glnP P ABC transporter permease
PMNHDPHM_01341 1e-68 ybfG M peptidoglycan-binding domain-containing protein
PMNHDPHM_01342 0.0 ybfG M peptidoglycan-binding domain-containing protein
PMNHDPHM_01347 7.8e-160 K sequence-specific DNA binding
PMNHDPHM_01348 1.4e-150 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_01349 1e-190 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_01350 1.6e-222 EGP Major facilitator Superfamily
PMNHDPHM_01351 1.3e-182 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_01352 1.6e-122 manY G PTS system
PMNHDPHM_01353 8.7e-170 manN G system, mannose fructose sorbose family IID component
PMNHDPHM_01354 4.4e-64 manO S Domain of unknown function (DUF956)
PMNHDPHM_01355 2.9e-173 iolS C Aldo keto reductase
PMNHDPHM_01356 2.2e-213 yeaN P Transporter, major facilitator family protein
PMNHDPHM_01357 4.1e-259 ydiC1 EGP Major Facilitator Superfamily
PMNHDPHM_01358 2.3e-113 ycaC Q Isochorismatase family
PMNHDPHM_01359 1e-90 S AAA domain
PMNHDPHM_01360 1.1e-83 F NUDIX domain
PMNHDPHM_01361 5.7e-183
PMNHDPHM_01362 4.7e-09
PMNHDPHM_01363 2.5e-152 S Protein of unknown function C-terminus (DUF2399)
PMNHDPHM_01364 1.1e-112 D Putative exonuclease SbcCD, C subunit
PMNHDPHM_01365 0.0 D Putative exonuclease SbcCD, C subunit
PMNHDPHM_01366 6.1e-188
PMNHDPHM_01367 9.9e-280
PMNHDPHM_01368 4.6e-160 yvfR V ABC transporter
PMNHDPHM_01369 3.5e-132 yvfS V ABC-2 type transporter
PMNHDPHM_01370 6.6e-204 desK 2.7.13.3 T Histidine kinase
PMNHDPHM_01371 1.6e-103 desR K helix_turn_helix, Lux Regulon
PMNHDPHM_01372 6.7e-117
PMNHDPHM_01373 8.8e-156 S Uncharacterised protein, DegV family COG1307
PMNHDPHM_01374 4.1e-86 K Acetyltransferase (GNAT) domain
PMNHDPHM_01375 1.1e-166 2.3.1.128 K Acetyltransferase (GNAT) domain
PMNHDPHM_01376 2.4e-110 K Psort location Cytoplasmic, score
PMNHDPHM_01377 4.2e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMNHDPHM_01378 1.9e-79 yphH S Cupin domain
PMNHDPHM_01379 3.8e-162 K Transcriptional regulator
PMNHDPHM_01380 3.9e-131 S ABC-2 family transporter protein
PMNHDPHM_01381 3.7e-168 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
PMNHDPHM_01382 3.2e-121 T Transcriptional regulatory protein, C terminal
PMNHDPHM_01383 1.6e-155 T GHKL domain
PMNHDPHM_01384 0.0 oppA E ABC transporter, substratebinding protein
PMNHDPHM_01385 2.3e-158 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PMNHDPHM_01386 8.9e-133 dck 2.7.1.74 F deoxynucleoside kinase
PMNHDPHM_01387 2.7e-137 pnuC H nicotinamide mononucleotide transporter
PMNHDPHM_01388 6.8e-170 IQ NAD dependent epimerase/dehydratase family
PMNHDPHM_01389 2.3e-156 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMNHDPHM_01390 2.5e-124 G Phosphoglycerate mutase family
PMNHDPHM_01391 6.6e-151 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
PMNHDPHM_01392 2e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
PMNHDPHM_01393 2.3e-110 yktB S Belongs to the UPF0637 family
PMNHDPHM_01394 3.2e-74 yueI S Protein of unknown function (DUF1694)
PMNHDPHM_01395 0.0 6.3.2.2, 6.3.2.4 M Mur ligase middle domain protein
PMNHDPHM_01396 4.3e-64 yugI 5.3.1.9 J general stress protein
PMNHDPHM_01397 2.6e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMNHDPHM_01398 4.7e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PMNHDPHM_01399 1.5e-86 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
PMNHDPHM_01400 2.3e-116 dedA S SNARE-like domain protein
PMNHDPHM_01401 1.9e-115 S Protein of unknown function (DUF1461)
PMNHDPHM_01402 1.7e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PMNHDPHM_01403 3.8e-113 yutD S Protein of unknown function (DUF1027)
PMNHDPHM_01404 1e-267 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PMNHDPHM_01405 1.8e-115 S Calcineurin-like phosphoesterase
PMNHDPHM_01406 5.9e-116 yibF S overlaps another CDS with the same product name
PMNHDPHM_01407 5.8e-189 yibE S overlaps another CDS with the same product name
PMNHDPHM_01408 2.1e-54
PMNHDPHM_01409 4.3e-258 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PMNHDPHM_01410 1.8e-275 pepV 3.5.1.18 E dipeptidase PepV
PMNHDPHM_01411 6.8e-136 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PMNHDPHM_01412 8.1e-128 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
PMNHDPHM_01413 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
PMNHDPHM_01414 2.3e-179 ccpA K catabolite control protein A
PMNHDPHM_01415 2.6e-216 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
PMNHDPHM_01416 5e-93 niaR S 3H domain
PMNHDPHM_01417 1.9e-78 ytxH S YtxH-like protein
PMNHDPHM_01419 9.3e-272 L Uncharacterised protein family (UPF0236)
PMNHDPHM_01420 2.4e-71 S COG NOG38524 non supervised orthologous group
PMNHDPHM_01421 6.1e-35
PMNHDPHM_01422 5.7e-65 nrp 1.20.4.1 P ArsC family
PMNHDPHM_01423 0.0 clpL O associated with various cellular activities
PMNHDPHM_01424 2e-143 ywqE 3.1.3.48 GM PHP domain protein
PMNHDPHM_01425 3.6e-160 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMNHDPHM_01426 6.7e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PMNHDPHM_01427 1.7e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PMNHDPHM_01428 1.4e-104 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PMNHDPHM_01429 0.0 res 2.1.1.72, 3.1.21.5 L Type III restriction enzyme, res subunit
PMNHDPHM_01430 4.2e-222 mod 2.1.1.72, 3.1.21.5 L DNA methylase
PMNHDPHM_01431 1.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMNHDPHM_01432 7.5e-194 yegS 2.7.1.107 G Lipid kinase
PMNHDPHM_01433 4.3e-280 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMNHDPHM_01434 2.3e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PMNHDPHM_01435 4.9e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMNHDPHM_01436 7.5e-203 camS S sex pheromone
PMNHDPHM_01437 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMNHDPHM_01438 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PMNHDPHM_01439 2e-28 yjgN S Bacterial protein of unknown function (DUF898)
PMNHDPHM_01440 1.8e-110 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
PMNHDPHM_01441 9.8e-190 S response to antibiotic
PMNHDPHM_01443 1.3e-251 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
PMNHDPHM_01444 5.3e-59
PMNHDPHM_01445 3.8e-82
PMNHDPHM_01446 5.2e-72 pheB 5.4.99.5 S Belongs to the UPF0735 family
PMNHDPHM_01447 7.6e-31
PMNHDPHM_01448 2.7e-94 yhbS S acetyltransferase
PMNHDPHM_01449 1.5e-275 yclK 2.7.13.3 T Histidine kinase
PMNHDPHM_01450 1.4e-133 K response regulator
PMNHDPHM_01451 5.8e-70 S SdpI/YhfL protein family
PMNHDPHM_01453 0.0 rafA 3.2.1.22 G alpha-galactosidase
PMNHDPHM_01454 2.5e-169 arbZ I Phosphate acyltransferases
PMNHDPHM_01455 4.2e-183 arbY M family 8
PMNHDPHM_01456 1.1e-163 arbx M Glycosyl transferase family 8
PMNHDPHM_01457 1.3e-147 arbV 2.3.1.51 I Phosphate acyltransferases
PMNHDPHM_01458 1.1e-248 cycA E Amino acid permease
PMNHDPHM_01459 2e-74
PMNHDPHM_01460 2.1e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
PMNHDPHM_01461 4.6e-49
PMNHDPHM_01462 1.1e-80
PMNHDPHM_01463 3.2e-53
PMNHDPHM_01465 1.3e-48
PMNHDPHM_01466 8.5e-168 comGB NU type II secretion system
PMNHDPHM_01467 1.1e-134 comGA NU Type II IV secretion system protein
PMNHDPHM_01468 3.4e-132 yebC K Transcriptional regulatory protein
PMNHDPHM_01469 3.3e-91 S VanZ like family
PMNHDPHM_01470 0.0 pepF2 E Oligopeptidase F
PMNHDPHM_01471 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PMNHDPHM_01472 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMNHDPHM_01473 1.2e-179 ybbR S YbbR-like protein
PMNHDPHM_01474 1e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PMNHDPHM_01475 7.1e-130 V AAA domain, putative AbiEii toxin, Type IV TA system
PMNHDPHM_01476 2.5e-190 V ABC transporter
PMNHDPHM_01477 4e-119 K Transcriptional regulator
PMNHDPHM_01478 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
PMNHDPHM_01480 1.1e-59
PMNHDPHM_01481 6.2e-81 S Domain of unknown function (DUF5067)
PMNHDPHM_01482 1.6e-207 potD P ABC transporter
PMNHDPHM_01483 8.9e-145 potC P ABC transporter permease
PMNHDPHM_01484 1.7e-148 potB P ABC transporter permease
PMNHDPHM_01485 4.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PMNHDPHM_01486 2.9e-96 puuR K Cupin domain
PMNHDPHM_01487 0.0 yjcE P Sodium proton antiporter
PMNHDPHM_01488 6.8e-167 murB 1.3.1.98 M Cell wall formation
PMNHDPHM_01489 8.8e-240 malE G Bacterial extracellular solute-binding protein
PMNHDPHM_01490 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
PMNHDPHM_01491 2.6e-166 malG P ABC-type sugar transport systems, permease components
PMNHDPHM_01492 1.6e-194 malK P ATPases associated with a variety of cellular activities
PMNHDPHM_01493 4.4e-103 3.2.2.20 K Acetyltransferase (GNAT) domain
PMNHDPHM_01494 9e-92 yxjI
PMNHDPHM_01495 3e-159 ycsE S Sucrose-6F-phosphate phosphohydrolase
PMNHDPHM_01496 4.6e-131 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PMNHDPHM_01497 6.5e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PMNHDPHM_01498 3.2e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
PMNHDPHM_01499 1.5e-166 natA S ABC transporter, ATP-binding protein
PMNHDPHM_01500 1.7e-219 ysdA CP ABC-2 family transporter protein
PMNHDPHM_01501 1.1e-98 dnaQ 2.7.7.7 L DNA polymerase III
PMNHDPHM_01502 4.9e-150 xth 3.1.11.2 L exodeoxyribonuclease III
PMNHDPHM_01504 2e-222 M Glycosyl hydrolases family 25
PMNHDPHM_01505 5e-78 M Glycosyl hydrolases family 25
PMNHDPHM_01506 1.4e-164 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PMNHDPHM_01507 1.7e-107 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PMNHDPHM_01508 3.9e-203 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PMNHDPHM_01509 5.2e-161 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PMNHDPHM_01510 1.9e-92
PMNHDPHM_01511 1.4e-240
PMNHDPHM_01512 6.4e-249
PMNHDPHM_01513 2.1e-111 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PMNHDPHM_01514 1.2e-97 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PMNHDPHM_01515 3.2e-154 nodB3 G Polysaccharide deacetylase
PMNHDPHM_01516 1.6e-238 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PMNHDPHM_01517 3.7e-165 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
PMNHDPHM_01518 0.0 E amino acid
PMNHDPHM_01519 1.4e-136 cysA V ABC transporter, ATP-binding protein
PMNHDPHM_01520 0.0 V FtsX-like permease family
PMNHDPHM_01521 1.2e-171 rhaD 4.1.2.17, 4.1.2.19, 5.1.3.4 H Catalyzes the reversible cleavage of L-rhamnulose-1- phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde
PMNHDPHM_01522 1.2e-128 pgm3 G Phosphoglycerate mutase family
PMNHDPHM_01523 9.2e-186 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PMNHDPHM_01524 3.7e-217 mntH P H( )-stimulated, divalent metal cation uptake system
PMNHDPHM_01525 3.1e-83 yjhE S Phage tail protein
PMNHDPHM_01526 3.2e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
PMNHDPHM_01527 0.0 yjbQ P TrkA C-terminal domain protein
PMNHDPHM_01528 1e-27
PMNHDPHM_01529 0.0 helD 3.6.4.12 L DNA helicase
PMNHDPHM_01530 8.5e-84 ykhA 3.1.2.20 I Thioesterase superfamily
PMNHDPHM_01531 5.7e-277 pipD E Dipeptidase
PMNHDPHM_01532 1.3e-42
PMNHDPHM_01533 4e-54
PMNHDPHM_01534 2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
PMNHDPHM_01535 3e-303 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PMNHDPHM_01538 2.2e-120 S WxL domain surface cell wall-binding
PMNHDPHM_01539 5.9e-64
PMNHDPHM_01540 1.6e-115 N WxL domain surface cell wall-binding
PMNHDPHM_01541 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
PMNHDPHM_01542 2.7e-169 yicL EG EamA-like transporter family
PMNHDPHM_01543 2.2e-114 L PFAM transposase, IS4 family protein
PMNHDPHM_01545 2.8e-44 L PFAM IS66 Orf2 family protein
PMNHDPHM_01546 5.4e-261 L Transposase IS66 family
PMNHDPHM_01547 6e-17
PMNHDPHM_01548 1e-187
PMNHDPHM_01550 1.1e-10 K Helix-turn-helix domain
PMNHDPHM_01551 7.6e-242 ydiC1 EGP Major facilitator Superfamily
PMNHDPHM_01552 5.8e-71 K helix_turn_helix multiple antibiotic resistance protein
PMNHDPHM_01553 7.9e-105
PMNHDPHM_01554 3.5e-29
PMNHDPHM_01555 5.4e-40 K Helix-turn-helix XRE-family like proteins
PMNHDPHM_01556 4e-56
PMNHDPHM_01557 1.6e-82
PMNHDPHM_01558 6.8e-273 manR K PRD domain
PMNHDPHM_01559 1.4e-69 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01560 1.6e-76 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01561 8.6e-48 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_01562 9e-145 G Phosphotransferase System
PMNHDPHM_01563 6.1e-120 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PMNHDPHM_01564 2.5e-129 alsE 5.1.3.1 G Ribulose-phosphate 3 epimerase family
PMNHDPHM_01565 5e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01566 1.9e-43 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
PMNHDPHM_01567 1.9e-103
PMNHDPHM_01568 2.7e-108 N Uncharacterized conserved protein (DUF2075)
PMNHDPHM_01569 2.4e-46 holB 2.7.7.7 L replication factor c
PMNHDPHM_01570 7.7e-120 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PMNHDPHM_01571 5.5e-107 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
PMNHDPHM_01573 1e-127 cobQ S glutamine amidotransferase
PMNHDPHM_01574 1.3e-66
PMNHDPHM_01575 2.8e-134 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PMNHDPHM_01576 2.4e-142 noc K Belongs to the ParB family
PMNHDPHM_01577 2.5e-138 soj D Sporulation initiation inhibitor
PMNHDPHM_01578 5.2e-156 spo0J K Belongs to the ParB family
PMNHDPHM_01579 1.3e-30 yyzM S Bacterial protein of unknown function (DUF951)
PMNHDPHM_01580 3e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PMNHDPHM_01581 7.3e-141 XK27_01040 S Protein of unknown function (DUF1129)
PMNHDPHM_01582 5.1e-268 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMNHDPHM_01583 1.3e-188 2.1.1.72 V Eco57I restriction-modification methylase
PMNHDPHM_01584 3.3e-200 L Belongs to the 'phage' integrase family
PMNHDPHM_01585 4.9e-51 2.1.1.72 V Eco57I restriction-modification methylase
PMNHDPHM_01586 1e-153 L PFAM Integrase catalytic region
PMNHDPHM_01587 9.1e-23 L Helix-turn-helix domain
PMNHDPHM_01589 1.9e-164 V ABC transporter
PMNHDPHM_01590 2.2e-196 amtB P Ammonium Transporter Family
PMNHDPHM_01591 2.8e-215 P Pyridine nucleotide-disulphide oxidoreductase
PMNHDPHM_01592 1.4e-125 usp 3.5.1.28 CBM50 D CHAP domain
PMNHDPHM_01593 0.0 ylbB V ABC transporter permease
PMNHDPHM_01594 6.3e-128 macB V ABC transporter, ATP-binding protein
PMNHDPHM_01595 1e-96 K transcriptional regulator
PMNHDPHM_01596 1e-153 supH G Sucrose-6F-phosphate phosphohydrolase
PMNHDPHM_01597 4.3e-47
PMNHDPHM_01598 4.1e-128 S membrane transporter protein
PMNHDPHM_01599 2.1e-103 S Protein of unknown function (DUF1211)
PMNHDPHM_01600 1.7e-113 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PMNHDPHM_01601 4.5e-55
PMNHDPHM_01602 7.3e-288 pipD E Dipeptidase
PMNHDPHM_01603 1.6e-106 S Membrane
PMNHDPHM_01604 2.2e-88
PMNHDPHM_01605 2.9e-52
PMNHDPHM_01607 1.2e-180 M Peptidoglycan-binding domain 1 protein
PMNHDPHM_01608 6.6e-49
PMNHDPHM_01609 0.0 ybfG M peptidoglycan-binding domain-containing protein
PMNHDPHM_01610 1.4e-122 azlC E branched-chain amino acid
PMNHDPHM_01611 1.5e-50 azlD S Branched-chain amino acid transport protein (AzlD)
PMNHDPHM_01612 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
PMNHDPHM_01613 0.0 M Glycosyl hydrolase family 59
PMNHDPHM_01615 1.4e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
PMNHDPHM_01616 1.3e-179 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
PMNHDPHM_01617 1.6e-168 uxaC 5.3.1.12 G glucuronate isomerase
PMNHDPHM_01618 2.6e-105 uxaC 5.3.1.12 G glucuronate isomerase
PMNHDPHM_01619 1.7e-217 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
PMNHDPHM_01620 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
PMNHDPHM_01621 6.2e-230 G Major Facilitator
PMNHDPHM_01622 9.2e-127 kdgR K FCD domain
PMNHDPHM_01623 2.7e-192 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
PMNHDPHM_01624 0.0 M Glycosyl hydrolase family 59
PMNHDPHM_01625 2.3e-59
PMNHDPHM_01626 2.7e-65 S pyridoxamine 5-phosphate
PMNHDPHM_01627 3.5e-247 EGP Major facilitator Superfamily
PMNHDPHM_01628 9e-220 3.1.1.83 I Alpha beta hydrolase
PMNHDPHM_01629 1.1e-119 K Bacterial regulatory proteins, tetR family
PMNHDPHM_01631 0.0 ydgH S MMPL family
PMNHDPHM_01632 2e-106 K Tetracycline repressor, C-terminal all-alpha domain
PMNHDPHM_01633 9.7e-122 S Sulfite exporter TauE/SafE
PMNHDPHM_01634 1.2e-249 3.5.4.28, 3.5.4.31 F Amidohydrolase family
PMNHDPHM_01635 1.9e-69 S An automated process has identified a potential problem with this gene model
PMNHDPHM_01636 2.1e-149 S Protein of unknown function (DUF3100)
PMNHDPHM_01638 1.9e-110 opuCD P Binding-protein-dependent transport system inner membrane component
PMNHDPHM_01639 5.4e-175 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PMNHDPHM_01640 4.7e-106 opuCB E ABC transporter permease
PMNHDPHM_01641 1.2e-214 opuCA E ABC transporter, ATP-binding protein
PMNHDPHM_01642 4.5e-52 S Protein of unknown function (DUF2568)
PMNHDPHM_01643 1e-69 K helix_turn_helix, mercury resistance
PMNHDPHM_01645 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
PMNHDPHM_01646 5.6e-33 copZ P Heavy-metal-associated domain
PMNHDPHM_01647 4.9e-102 dps P Belongs to the Dps family
PMNHDPHM_01648 1.6e-117 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
PMNHDPHM_01649 4.1e-98 K Bacterial regulatory proteins, tetR family
PMNHDPHM_01650 1.5e-89 S Protein of unknown function with HXXEE motif
PMNHDPHM_01652 9.3e-161 S CAAX protease self-immunity
PMNHDPHM_01653 4.3e-203 manY 2.7.1.191, 2.7.1.202 G phosphotransferase system
PMNHDPHM_01654 3.6e-48 manY 2.7.1.191, 2.7.1.202 G phosphotransferase system
PMNHDPHM_01655 8.5e-81 frvA 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01656 0.0 mngB 3.2.1.170 GH38 G Glycosyl hydrolases family 38 N-terminal domain
PMNHDPHM_01657 7.4e-141 K SIS domain
PMNHDPHM_01658 1.5e-279 bgl 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_01659 5.8e-163 bglK_1 2.7.1.2 GK ROK family
PMNHDPHM_01661 5.6e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PMNHDPHM_01662 1.7e-229 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PMNHDPHM_01663 9e-107 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
PMNHDPHM_01664 2.2e-137 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PMNHDPHM_01665 4.1e-184 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMNHDPHM_01666 0.0 norB EGP Major Facilitator
PMNHDPHM_01667 5.5e-112 K Bacterial regulatory proteins, tetR family
PMNHDPHM_01668 6.2e-123
PMNHDPHM_01670 6.8e-107 1.1.1.133, 5.1.3.13 M dTDP-4-dehydrorhamnose 3,5-epimerase
PMNHDPHM_01671 1e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PMNHDPHM_01672 1.8e-167 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMNHDPHM_01673 4.6e-224 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PMNHDPHM_01674 2e-73 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PMNHDPHM_01675 1.7e-259 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PMNHDPHM_01676 6.2e-260 lysC 2.7.2.4 E Belongs to the aspartokinase family
PMNHDPHM_01677 1.2e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PMNHDPHM_01678 6.7e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMNHDPHM_01679 6.6e-63
PMNHDPHM_01680 1.2e-49 K sequence-specific DNA binding
PMNHDPHM_01681 1.4e-74 3.6.1.55 L NUDIX domain
PMNHDPHM_01682 1.1e-153 EG EamA-like transporter family
PMNHDPHM_01684 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PMNHDPHM_01685 5.1e-70 rplI J Binds to the 23S rRNA
PMNHDPHM_01686 3.2e-248 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PMNHDPHM_01687 2.1e-221
PMNHDPHM_01688 0.0 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMNHDPHM_01689 1.1e-162 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PMNHDPHM_01690 3.5e-199 4.2.1.126 S Bacterial protein of unknown function (DUF871)
PMNHDPHM_01691 1.6e-157 K Helix-turn-helix domain, rpiR family
PMNHDPHM_01692 1.8e-107 K Transcriptional regulator C-terminal region
PMNHDPHM_01693 4.9e-128 V ABC transporter, ATP-binding protein
PMNHDPHM_01694 0.0 ylbB V ABC transporter permease
PMNHDPHM_01695 1.2e-207 4.1.1.52 S Amidohydrolase
PMNHDPHM_01696 4.9e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMNHDPHM_01697 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
PMNHDPHM_01698 1.2e-55 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
PMNHDPHM_01699 2.4e-207 yxaM EGP Major facilitator Superfamily
PMNHDPHM_01700 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PMNHDPHM_01701 5.5e-132
PMNHDPHM_01702 9.4e-27
PMNHDPHM_01705 2.1e-152 K Bacteriophage CI repressor helix-turn-helix domain
PMNHDPHM_01706 4e-162 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PMNHDPHM_01707 2.6e-160 tktN 2.2.1.1 G Transketolase, thiamine diphosphate binding domain
PMNHDPHM_01708 1.3e-190 tktC 2.2.1.1 G Transketolase
PMNHDPHM_01709 1.4e-166 gmuE 2.7.1.2, 2.7.1.4 GK ROK family
PMNHDPHM_01710 1.2e-132 K DeoR C terminal sensor domain
PMNHDPHM_01711 3.1e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_01712 4.1e-53 fruA 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_01713 1.1e-163 G Phosphotransferase System
PMNHDPHM_01714 5.8e-39 L Transposase and inactivated derivatives
PMNHDPHM_01715 2.1e-148 L Integrase core domain
PMNHDPHM_01716 3.6e-162 L PFAM Integrase catalytic region
PMNHDPHM_01717 1.3e-41
PMNHDPHM_01718 0.0 pacL 3.6.3.8 P P-type ATPase
PMNHDPHM_01720 2.8e-171 L Transposase
PMNHDPHM_01721 2.1e-182 yveB 2.7.4.29 I PAP2 superfamily
PMNHDPHM_01722 5.8e-213 mccF V LD-carboxypeptidase
PMNHDPHM_01723 2.5e-42
PMNHDPHM_01724 2.1e-207 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PMNHDPHM_01725 1.1e-40
PMNHDPHM_01726 1e-111
PMNHDPHM_01727 9.1e-227 EGP Major facilitator Superfamily
PMNHDPHM_01728 9.6e-239 rarA L recombination factor protein RarA
PMNHDPHM_01729 1.3e-85
PMNHDPHM_01730 8.7e-92 S MucBP domain
PMNHDPHM_01731 2.9e-119 ywnB S NAD(P)H-binding
PMNHDPHM_01734 3.5e-88 E AAA domain
PMNHDPHM_01735 1.9e-122 E lipolytic protein G-D-S-L family
PMNHDPHM_01736 8.5e-102 feoA P FeoA
PMNHDPHM_01737 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PMNHDPHM_01738 1.6e-24 S Virus attachment protein p12 family
PMNHDPHM_01739 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
PMNHDPHM_01740 1e-56
PMNHDPHM_01741 3.7e-234 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
PMNHDPHM_01742 1.6e-263 G MFS/sugar transport protein
PMNHDPHM_01743 5.4e-74 S function, without similarity to other proteins
PMNHDPHM_01744 1.4e-65
PMNHDPHM_01745 0.0 macB_3 V ABC transporter, ATP-binding protein
PMNHDPHM_01746 3e-257 dtpT U amino acid peptide transporter
PMNHDPHM_01747 7.5e-160 yjjH S Calcineurin-like phosphoesterase
PMNHDPHM_01749 8.6e-284 mga K Mga helix-turn-helix domain
PMNHDPHM_01750 0.0 sprD D Domain of Unknown Function (DUF1542)
PMNHDPHM_01751 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
PMNHDPHM_01752 1.2e-138 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PMNHDPHM_01753 1.7e-218 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PMNHDPHM_01754 6.6e-125 gntR1 K UbiC transcription regulator-associated domain protein
PMNHDPHM_01755 1e-281 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMNHDPHM_01756 6.8e-223 V Beta-lactamase
PMNHDPHM_01757 1.3e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PMNHDPHM_01758 2.4e-217 V Beta-lactamase
PMNHDPHM_01759 0.0 pacL 3.6.3.8 P P-type ATPase
PMNHDPHM_01760 1.3e-73
PMNHDPHM_01761 8e-177 XK27_08835 S ABC transporter
PMNHDPHM_01762 1.1e-129 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
PMNHDPHM_01763 5e-131 XK27_08845 S ABC transporter, ATP-binding protein
PMNHDPHM_01764 6.2e-84 ydcK S Belongs to the SprT family
PMNHDPHM_01765 6.6e-81 yodP 2.3.1.264 K FR47-like protein
PMNHDPHM_01767 1.5e-101 S ECF transporter, substrate-specific component
PMNHDPHM_01768 8e-213 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
PMNHDPHM_01769 1.2e-160 5.1.3.3 G Aldose 1-epimerase
PMNHDPHM_01770 2.2e-102 V Restriction endonuclease
PMNHDPHM_01771 3e-161 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
PMNHDPHM_01772 3.3e-49
PMNHDPHM_01773 2e-211 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
PMNHDPHM_01774 2.3e-221 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
PMNHDPHM_01775 1.6e-221 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
PMNHDPHM_01776 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMNHDPHM_01777 1.2e-80 F Nucleoside 2-deoxyribosyltransferase
PMNHDPHM_01778 3.7e-257 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMNHDPHM_01779 6e-64
PMNHDPHM_01780 2.3e-292 frvR K Mga helix-turn-helix domain
PMNHDPHM_01781 1.8e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
PMNHDPHM_01782 1.4e-104 ygaC J Belongs to the UPF0374 family
PMNHDPHM_01783 4.3e-97
PMNHDPHM_01784 8.6e-75 S Acetyltransferase (GNAT) domain
PMNHDPHM_01785 5.2e-207 yueF S AI-2E family transporter
PMNHDPHM_01786 4.6e-244 hlyX S Transporter associated domain
PMNHDPHM_01787 1.9e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PMNHDPHM_01788 4.3e-46 XK27_09445 S Domain of unknown function (DUF1827)
PMNHDPHM_01789 0.0 clpE O Belongs to the ClpA ClpB family
PMNHDPHM_01790 2e-28
PMNHDPHM_01791 2.7e-39 ptsH G phosphocarrier protein HPR
PMNHDPHM_01792 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PMNHDPHM_01793 2.8e-255 iolT EGP Major facilitator Superfamily
PMNHDPHM_01794 7e-267 L Transposase DDE domain
PMNHDPHM_01795 0.0 L AAA ATPase domain
PMNHDPHM_01796 0.0 3.6.4.12 L UvrD/REP helicase N-terminal domain
PMNHDPHM_01797 1.7e-240 YSH1 S Metallo-beta-lactamase superfamily
PMNHDPHM_01798 8.7e-50
PMNHDPHM_01799 4.4e-118 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
PMNHDPHM_01800 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
PMNHDPHM_01801 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
PMNHDPHM_01802 4.2e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PMNHDPHM_01803 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PMNHDPHM_01804 6.4e-139 est 3.1.1.1 S Serine aminopeptidase, S33
PMNHDPHM_01805 9.3e-31 secG U Preprotein translocase
PMNHDPHM_01806 1.7e-60
PMNHDPHM_01807 5.7e-294 clcA P chloride
PMNHDPHM_01808 1.2e-64
PMNHDPHM_01809 3.7e-246 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PMNHDPHM_01810 1.7e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PMNHDPHM_01811 1.5e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PMNHDPHM_01812 2.2e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PMNHDPHM_01813 3.6e-188 cggR K Putative sugar-binding domain
PMNHDPHM_01815 2.5e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PMNHDPHM_01816 5.5e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
PMNHDPHM_01817 5.7e-172 whiA K May be required for sporulation
PMNHDPHM_01818 9.1e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PMNHDPHM_01819 1.3e-165 rapZ S Displays ATPase and GTPase activities
PMNHDPHM_01820 3.9e-85 S Short repeat of unknown function (DUF308)
PMNHDPHM_01821 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PMNHDPHM_01822 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PMNHDPHM_01823 1.9e-118 yfbR S HD containing hydrolase-like enzyme
PMNHDPHM_01824 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
PMNHDPHM_01825 1.5e-180 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PMNHDPHM_01826 1.8e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PMNHDPHM_01827 7.7e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PMNHDPHM_01828 2.8e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PMNHDPHM_01829 1.3e-46 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PMNHDPHM_01830 7.1e-32
PMNHDPHM_01831 3.7e-218 yvlB S Putative adhesin
PMNHDPHM_01832 8e-134 L Helix-turn-helix domain
PMNHDPHM_01833 1.3e-138 L hmm pf00665
PMNHDPHM_01834 1e-119 phoU P Plays a role in the regulation of phosphate uptake
PMNHDPHM_01835 7.1e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMNHDPHM_01836 6.9e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMNHDPHM_01837 1.1e-156 pstA P Phosphate transport system permease protein PstA
PMNHDPHM_01838 3.4e-161 pstC P probably responsible for the translocation of the substrate across the membrane
PMNHDPHM_01839 5.2e-156 pstS P Phosphate
PMNHDPHM_01840 1.1e-306 phoR 2.7.13.3 T Histidine kinase
PMNHDPHM_01841 5.2e-130 K response regulator
PMNHDPHM_01842 2.8e-199 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
PMNHDPHM_01843 1.8e-159 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PMNHDPHM_01844 1.9e-124 ftsE D ABC transporter
PMNHDPHM_01845 3.1e-176 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMNHDPHM_01846 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PMNHDPHM_01847 4.7e-10
PMNHDPHM_01848 5.4e-98 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMNHDPHM_01849 1.3e-90 comFC S Competence protein
PMNHDPHM_01850 1.5e-236 comFA L Helicase C-terminal domain protein
PMNHDPHM_01851 1.7e-119 yvyE 3.4.13.9 S YigZ family
PMNHDPHM_01852 1.7e-242 rny S Endoribonuclease that initiates mRNA decay
PMNHDPHM_01853 1.9e-23
PMNHDPHM_01854 1.9e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMNHDPHM_01855 3.3e-228 cinA 3.5.1.42 S Belongs to the CinA family
PMNHDPHM_01856 1.2e-103 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMNHDPHM_01857 2e-116 ymfM S Helix-turn-helix domain
PMNHDPHM_01858 6e-129 IQ Enoyl-(Acyl carrier protein) reductase
PMNHDPHM_01859 8.1e-246 ymfH S Peptidase M16
PMNHDPHM_01860 1.2e-230 ymfF S Peptidase M16 inactive domain protein
PMNHDPHM_01861 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PMNHDPHM_01862 5.4e-71 WQ51_03320 S Protein of unknown function (DUF1149)
PMNHDPHM_01863 1.6e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PMNHDPHM_01864 7.3e-155 rrmA 2.1.1.187 H Methyltransferase
PMNHDPHM_01865 5.7e-172 corA P CorA-like Mg2+ transporter protein
PMNHDPHM_01866 2e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
PMNHDPHM_01867 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMNHDPHM_01868 4.2e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
PMNHDPHM_01869 7.1e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
PMNHDPHM_01870 3.5e-146 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PMNHDPHM_01871 1.8e-113 cutC P Participates in the control of copper homeostasis
PMNHDPHM_01872 3.1e-203 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PMNHDPHM_01873 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
PMNHDPHM_01874 2.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PMNHDPHM_01875 2e-123 yjbM 2.7.6.5 S RelA SpoT domain protein
PMNHDPHM_01876 2.4e-104 yjbK S CYTH
PMNHDPHM_01877 1.5e-115 yjbH Q Thioredoxin
PMNHDPHM_01878 7.2e-216 coiA 3.6.4.12 S Competence protein
PMNHDPHM_01879 1.7e-246 XK27_08635 S UPF0210 protein
PMNHDPHM_01880 6.7e-38 gcvR T Belongs to the UPF0237 family
PMNHDPHM_01881 5.8e-64 S acid phosphatase activity
PMNHDPHM_01882 7e-186 cpdA S Calcineurin-like phosphoesterase
PMNHDPHM_01883 1.6e-227 malY 4.4.1.8 E Aminotransferase, class I
PMNHDPHM_01884 4.8e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PMNHDPHM_01886 2.7e-95 FNV0100 F NUDIX domain
PMNHDPHM_01887 4.1e-142 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMNHDPHM_01888 3.3e-35 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
PMNHDPHM_01889 2.4e-130 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMNHDPHM_01890 2.2e-280 ytgP S Polysaccharide biosynthesis protein
PMNHDPHM_01891 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMNHDPHM_01892 1e-122 3.6.1.27 I Acid phosphatase homologues
PMNHDPHM_01893 1.1e-114 S Domain of unknown function (DUF4811)
PMNHDPHM_01894 8.1e-266 lmrB EGP Major facilitator Superfamily
PMNHDPHM_01895 1e-81 merR K MerR HTH family regulatory protein
PMNHDPHM_01896 2.5e-275 emrY EGP Major facilitator Superfamily
PMNHDPHM_01897 1.7e-210 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PMNHDPHM_01898 3.6e-101
PMNHDPHM_01903 1e-80 V HNH nucleases
PMNHDPHM_01904 4.7e-67 L Single-strand binding protein family
PMNHDPHM_01905 6.5e-134
PMNHDPHM_01906 3.1e-111 S CAAX protease self-immunity
PMNHDPHM_01908 6.3e-100 pfoS S Phosphotransferase system, EIIC
PMNHDPHM_01909 1.5e-68
PMNHDPHM_01910 4.7e-168 yqiK S SPFH domain / Band 7 family
PMNHDPHM_01911 1.9e-253 yclM 2.7.2.4 E Belongs to the aspartokinase family
PMNHDPHM_01912 8.1e-232 hom 1.1.1.3 E homoserine dehydrogenase
PMNHDPHM_01913 2.5e-286 thrC 4.2.3.1 E Threonine synthase
PMNHDPHM_01914 1.3e-159 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PMNHDPHM_01915 1.6e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
PMNHDPHM_01916 1.1e-67 usp1 T Universal stress protein family
PMNHDPHM_01917 4e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PMNHDPHM_01918 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PMNHDPHM_01919 3.8e-224 G Major Facilitator Superfamily
PMNHDPHM_01920 1e-178 L Transposase and inactivated derivatives, IS30 family
PMNHDPHM_01921 2.8e-293 clcA P chloride
PMNHDPHM_01922 5.7e-126 tnp L DDE domain
PMNHDPHM_01923 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
PMNHDPHM_01924 2.6e-49
PMNHDPHM_01925 8.4e-156 S Protein of unknown function (DUF2785)
PMNHDPHM_01930 1.4e-77 S ECF-type riboflavin transporter, S component
PMNHDPHM_01931 7.7e-146 CcmA5 V ABC transporter
PMNHDPHM_01932 0.0
PMNHDPHM_01933 2.2e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
PMNHDPHM_01934 1.4e-181 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMNHDPHM_01935 1.6e-62 pfoS S Phosphotransferase system, EIIC
PMNHDPHM_01936 9.3e-115 ylbE GM NAD(P)H-binding
PMNHDPHM_01937 3.4e-160 yeaE S Aldo/keto reductase family
PMNHDPHM_01938 1.7e-257 yifK E Amino acid permease
PMNHDPHM_01939 1.7e-296 S Protein of unknown function (DUF3800)
PMNHDPHM_01940 0.0 yjcE P Sodium proton antiporter
PMNHDPHM_01941 2.2e-56 S Protein of unknown function (DUF3021)
PMNHDPHM_01942 4.9e-73 K LytTr DNA-binding domain
PMNHDPHM_01943 1.4e-148 cylB V ABC-2 type transporter
PMNHDPHM_01944 6.6e-162 cylA V ABC transporter
PMNHDPHM_01945 1.4e-147 S Alpha/beta hydrolase of unknown function (DUF915)
PMNHDPHM_01946 3.8e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
PMNHDPHM_01947 1.2e-52 ybjQ S Belongs to the UPF0145 family
PMNHDPHM_01948 1.4e-95 nudC 1.3.7.1, 3.6.1.22 L NUDIX domain
PMNHDPHM_01949 2.8e-119 K response regulator
PMNHDPHM_01950 6.5e-165 T PhoQ Sensor
PMNHDPHM_01951 8.2e-168 ycbN V ABC transporter, ATP-binding protein
PMNHDPHM_01952 1.3e-114 S ABC-2 family transporter protein
PMNHDPHM_01953 2.9e-165 3.5.1.10 C nadph quinone reductase
PMNHDPHM_01954 1.6e-244 amt P ammonium transporter
PMNHDPHM_01955 1.1e-178 yfeX P Peroxidase
PMNHDPHM_01956 3e-119 yhiD S MgtC family
PMNHDPHM_01957 9.3e-147 F DNA RNA non-specific endonuclease
PMNHDPHM_01959 0.0 ybiT S ABC transporter, ATP-binding protein
PMNHDPHM_01960 8.6e-145 mutS L ATPase domain of DNA mismatch repair MUTS family
PMNHDPHM_01961 2.1e-157 mutS L ATPase domain of DNA mismatch repair MUTS family
PMNHDPHM_01962 1.8e-112 ung2 3.2.2.27 L Uracil-DNA glycosylase
PMNHDPHM_01963 1.9e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMNHDPHM_01964 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
PMNHDPHM_01965 5.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMNHDPHM_01966 1.8e-138 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
PMNHDPHM_01969 1.1e-138 lacT K PRD domain
PMNHDPHM_01970 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
PMNHDPHM_01971 3.1e-135 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_01972 3.2e-135 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_01973 1.9e-50 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_01974 7.4e-222 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PMNHDPHM_01975 5.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PMNHDPHM_01976 5.8e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
PMNHDPHM_01977 1.5e-162 K Transcriptional regulator
PMNHDPHM_01978 1.3e-193 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PMNHDPHM_01979 5.5e-221 gatC G PTS system sugar-specific permease component
PMNHDPHM_01981 1.5e-29
PMNHDPHM_01982 1.9e-189 V Beta-lactamase
PMNHDPHM_01983 8e-128 S Domain of unknown function (DUF4867)
PMNHDPHM_01984 9.9e-177 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
PMNHDPHM_01985 1.3e-187 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
PMNHDPHM_01986 9.9e-94 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
PMNHDPHM_01987 6.1e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
PMNHDPHM_01988 1.9e-141 lacR K DeoR C terminal sensor domain
PMNHDPHM_01989 9.1e-118 gph 3.1.3.18 S HAD hydrolase, family IA, variant
PMNHDPHM_01990 1.1e-211 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PMNHDPHM_01991 0.0 sbcC L Putative exonuclease SbcCD, C subunit
PMNHDPHM_01992 3.7e-14
PMNHDPHM_01993 3.1e-86 hsp1 O Belongs to the small heat shock protein (HSP20) family
PMNHDPHM_01994 1.1e-212 mutY L A G-specific adenine glycosylase
PMNHDPHM_01995 2.7e-151 cytC6 I alpha/beta hydrolase fold
PMNHDPHM_01996 3.1e-122 yrkL S Flavodoxin-like fold
PMNHDPHM_01998 1.7e-88 S Short repeat of unknown function (DUF308)
PMNHDPHM_01999 7.9e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
PMNHDPHM_02000 1.2e-199
PMNHDPHM_02001 6.6e-07
PMNHDPHM_02002 1.2e-117 ywnB S NmrA-like family
PMNHDPHM_02003 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
PMNHDPHM_02005 1.5e-167 XK27_00670 S ABC transporter substrate binding protein
PMNHDPHM_02007 2e-167 XK27_00670 S ABC transporter
PMNHDPHM_02008 7.6e-156 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
PMNHDPHM_02009 6.1e-143 cmpC S ABC transporter, ATP-binding protein
PMNHDPHM_02010 1.2e-174 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
PMNHDPHM_02011 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
PMNHDPHM_02012 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
PMNHDPHM_02013 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PMNHDPHM_02014 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PMNHDPHM_02015 1.1e-86 ypmB S Protein conserved in bacteria
PMNHDPHM_02016 2.4e-220 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PMNHDPHM_02017 4.2e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
PMNHDPHM_02018 1.1e-112 dnaD L DnaD domain protein
PMNHDPHM_02019 9.7e-115 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMNHDPHM_02020 2.3e-86 comEB 3.5.4.12 F ComE operon protein 2
PMNHDPHM_02021 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
PMNHDPHM_02022 6.7e-121 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PMNHDPHM_02023 1.7e-107 ypsA S Belongs to the UPF0398 family
PMNHDPHM_02024 1.8e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
PMNHDPHM_02026 9.7e-219 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PMNHDPHM_02027 7.1e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
PMNHDPHM_02028 1.5e-33
PMNHDPHM_02029 3.3e-194 lplA 6.3.1.20 H Lipoate-protein ligase
PMNHDPHM_02030 0.0 pepO 3.4.24.71 O Peptidase family M13
PMNHDPHM_02031 7.5e-166 K Transcriptional regulator
PMNHDPHM_02032 4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMNHDPHM_02033 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMNHDPHM_02034 4.5e-38 nrdH O Glutaredoxin
PMNHDPHM_02035 5.1e-273 K Mga helix-turn-helix domain
PMNHDPHM_02036 2e-55
PMNHDPHM_02037 4.7e-282 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMNHDPHM_02038 1.5e-109 XK27_02070 S Nitroreductase family
PMNHDPHM_02039 1.1e-68 rnhA 3.1.26.4 L Ribonuclease HI
PMNHDPHM_02040 3.7e-64 S Family of unknown function (DUF5322)
PMNHDPHM_02041 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PMNHDPHM_02042 9.2e-82 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMNHDPHM_02043 1.3e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PMNHDPHM_02045 1.3e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PMNHDPHM_02046 1.5e-236 pyrP F Permease
PMNHDPHM_02047 3.3e-180 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PMNHDPHM_02048 6.5e-240 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PMNHDPHM_02049 1e-209 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
PMNHDPHM_02050 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
PMNHDPHM_02051 1.2e-155 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PMNHDPHM_02052 7.2e-127 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PMNHDPHM_02053 5.3e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMNHDPHM_02054 3.2e-193 pfoS S Phosphotransferase system, EIIC
PMNHDPHM_02055 6.2e-51 S MazG-like family
PMNHDPHM_02056 0.0 FbpA K Fibronectin-binding protein
PMNHDPHM_02058 3.2e-161 degV S EDD domain protein, DegV family
PMNHDPHM_02059 1.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
PMNHDPHM_02060 3.9e-209 hisC 2.6.1.9 E Cys/Met metabolism PLP-dependent enzyme
PMNHDPHM_02061 3.1e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PMNHDPHM_02062 2.4e-110 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PMNHDPHM_02063 8.1e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PMNHDPHM_02064 1.7e-105 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PMNHDPHM_02065 1e-113 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PMNHDPHM_02066 4e-136 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PMNHDPHM_02067 1.3e-134 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PMNHDPHM_02068 1.6e-57 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PMNHDPHM_02069 6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PMNHDPHM_02070 5.2e-209 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMNHDPHM_02071 1.2e-149 Q Fumarylacetoacetate (FAA) hydrolase family
PMNHDPHM_02072 8.9e-113 nfnB 1.5.1.34 C Nitroreductase family
PMNHDPHM_02073 6.9e-71 K Acetyltransferase (GNAT) domain
PMNHDPHM_02074 5.4e-68 msi198 K Acetyltransferase (GNAT) domain
PMNHDPHM_02075 1.5e-222 EGP Transmembrane secretion effector
PMNHDPHM_02076 1.7e-128 T Transcriptional regulatory protein, C terminal
PMNHDPHM_02077 2.5e-175 T Histidine kinase-like ATPases
PMNHDPHM_02078 2.6e-135 XK27_05695 V ABC transporter, ATP-binding protein
PMNHDPHM_02079 0.0 ysaB V FtsX-like permease family
PMNHDPHM_02080 9.5e-211 xerS L Belongs to the 'phage' integrase family
PMNHDPHM_02081 9.5e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
PMNHDPHM_02082 1.8e-181 K LysR substrate binding domain
PMNHDPHM_02083 4.3e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMNHDPHM_02084 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PMNHDPHM_02085 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMNHDPHM_02086 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PMNHDPHM_02087 3.1e-110 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PMNHDPHM_02088 9.6e-174 lacX 5.1.3.3 G Aldose 1-epimerase
PMNHDPHM_02089 5e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
PMNHDPHM_02090 5.5e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
PMNHDPHM_02091 1.2e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PMNHDPHM_02092 7.7e-252 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PMNHDPHM_02093 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMNHDPHM_02094 1.7e-148 dprA LU DNA protecting protein DprA
PMNHDPHM_02095 9.2e-141 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMNHDPHM_02096 1.4e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PMNHDPHM_02097 1e-133 S Domain of unknown function (DUF4918)
PMNHDPHM_02099 2.9e-59
PMNHDPHM_02100 1.5e-259 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
PMNHDPHM_02101 2.3e-40 yozE S Belongs to the UPF0346 family
PMNHDPHM_02102 9.5e-97 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMNHDPHM_02103 8.1e-114 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
PMNHDPHM_02104 7.8e-157 ypmR E GDSL-like Lipase/Acylhydrolase
PMNHDPHM_02105 2.3e-148 DegV S EDD domain protein, DegV family
PMNHDPHM_02106 9.6e-115 hly S protein, hemolysin III
PMNHDPHM_02107 3e-92 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PMNHDPHM_02108 3.8e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PMNHDPHM_02109 0.0 yfmR S ABC transporter, ATP-binding protein
PMNHDPHM_02110 9.6e-85
PMNHDPHM_02111 9.5e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PMNHDPHM_02112 4.8e-149 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMNHDPHM_02113 1.8e-237 S Tetratricopeptide repeat protein
PMNHDPHM_02114 2e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PMNHDPHM_02115 5.3e-245 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PMNHDPHM_02116 1.1e-218 rpsA 1.17.7.4 J Ribosomal protein S1
PMNHDPHM_02117 5.3e-116 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PMNHDPHM_02118 1.1e-57 M Lysin motif
PMNHDPHM_02119 1.7e-268 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMNHDPHM_02120 8e-185 ypbB 5.1.3.1 S Helix-turn-helix domain
PMNHDPHM_02121 1.4e-45 fer C 4Fe-4S single cluster domain of Ferredoxin I
PMNHDPHM_02122 2.4e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PMNHDPHM_02123 9.4e-138 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMNHDPHM_02124 5.1e-105 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PMNHDPHM_02125 7.3e-127 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PMNHDPHM_02126 3.4e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PMNHDPHM_02127 3.3e-166 xerD D recombinase XerD
PMNHDPHM_02128 4.8e-165 cvfB S S1 domain
PMNHDPHM_02129 1.9e-72 yeaL S Protein of unknown function (DUF441)
PMNHDPHM_02130 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PMNHDPHM_02131 3.5e-177 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PMNHDPHM_02132 0.0 dnaE 2.7.7.7 L DNA polymerase
PMNHDPHM_02133 1.3e-19 S Protein of unknown function (DUF2929)
PMNHDPHM_02134 3.7e-146
PMNHDPHM_02135 7.3e-302 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
PMNHDPHM_02136 9.6e-95 M1-874 K Domain of unknown function (DUF1836)
PMNHDPHM_02137 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PMNHDPHM_02138 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMNHDPHM_02139 1.3e-46 yrvD S Lipopolysaccharide assembly protein A domain
PMNHDPHM_02140 1e-142 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
PMNHDPHM_02141 1.5e-183 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PMNHDPHM_02142 0.0 oatA I Acyltransferase
PMNHDPHM_02143 2.1e-233 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PMNHDPHM_02144 7.7e-132 fruR K DeoR C terminal sensor domain
PMNHDPHM_02145 6.9e-159 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PMNHDPHM_02146 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
PMNHDPHM_02147 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PMNHDPHM_02148 2.4e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
PMNHDPHM_02149 6.5e-260 glnPH2 P ABC transporter permease
PMNHDPHM_02150 2.3e-20
PMNHDPHM_02151 1e-47 MA20_27270 S mazG nucleotide pyrophosphohydrolase
PMNHDPHM_02152 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
PMNHDPHM_02153 2.9e-232 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMNHDPHM_02154 3.2e-197 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PMNHDPHM_02155 0.0 yknV V ABC transporter
PMNHDPHM_02156 5.5e-65 rmeD K helix_turn_helix, mercury resistance
PMNHDPHM_02157 1.7e-63 pcaC 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMNHDPHM_02158 2.7e-137 cobB K Sir2 family
PMNHDPHM_02159 1.6e-49 M Protein of unknown function (DUF3737)
PMNHDPHM_02160 6.7e-33 M Protein of unknown function (DUF3737)
PMNHDPHM_02161 4.6e-163 S Tetratricopeptide repeat
PMNHDPHM_02162 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMNHDPHM_02163 5.3e-127
PMNHDPHM_02164 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PMNHDPHM_02165 2.3e-35 rpsT J Binds directly to 16S ribosomal RNA
PMNHDPHM_02166 2e-194 holA 2.7.7.7 L DNA polymerase III delta subunit
PMNHDPHM_02167 0.0 comEC S Competence protein ComEC
PMNHDPHM_02168 7.4e-118 comEA L Competence protein ComEA
PMNHDPHM_02169 5.5e-195 ylbL T Belongs to the peptidase S16 family
PMNHDPHM_02170 2.8e-85 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PMNHDPHM_02171 1.6e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
PMNHDPHM_02172 3.8e-57 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
PMNHDPHM_02173 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
PMNHDPHM_02174 3.8e-210 ftsW D Belongs to the SEDS family
PMNHDPHM_02175 0.0 typA T GTP-binding protein TypA
PMNHDPHM_02176 5.9e-146 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PMNHDPHM_02177 1.4e-46 yktA S Belongs to the UPF0223 family
PMNHDPHM_02178 8.3e-157 1.1.1.27 C L-malate dehydrogenase activity
PMNHDPHM_02179 3.7e-260 lpdA 1.8.1.4 C Dehydrogenase
PMNHDPHM_02180 2.1e-212 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PMNHDPHM_02181 4.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
PMNHDPHM_02182 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PMNHDPHM_02183 8.7e-137 S E1-E2 ATPase
PMNHDPHM_02184 1.2e-100 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PMNHDPHM_02185 2e-74
PMNHDPHM_02187 4.9e-31 ykzG S Belongs to the UPF0356 family
PMNHDPHM_02188 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMNHDPHM_02189 2.2e-184 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
PMNHDPHM_02190 2.1e-243 els S Sterol carrier protein domain
PMNHDPHM_02191 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PMNHDPHM_02192 1.1e-118 S Repeat protein
PMNHDPHM_02193 1.3e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
PMNHDPHM_02194 6.7e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PMNHDPHM_02195 0.0 uvrA2 L ABC transporter
PMNHDPHM_02196 2.6e-58 XK27_04120 S Putative amino acid metabolism
PMNHDPHM_02197 1.4e-220 iscS 2.8.1.7 E Aminotransferase class V
PMNHDPHM_02198 2.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PMNHDPHM_02199 2.6e-34
PMNHDPHM_02200 3.1e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
PMNHDPHM_02201 6.9e-116 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
PMNHDPHM_02202 6.2e-208 yaaN P Toxic anion resistance protein (TelA)
PMNHDPHM_02203 3.6e-263 ydiC1 EGP Major facilitator Superfamily
PMNHDPHM_02204 1.5e-145 pstS P Phosphate
PMNHDPHM_02205 8.2e-37 cspA K Cold shock protein
PMNHDPHM_02206 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PMNHDPHM_02207 2.2e-81 divIVA D DivIVA protein
PMNHDPHM_02208 5.8e-146 ylmH S S4 domain protein
PMNHDPHM_02209 1.8e-44 yggT D integral membrane protein
PMNHDPHM_02210 6.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PMNHDPHM_02211 3.1e-218 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMNHDPHM_02212 3.6e-233 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PMNHDPHM_02213 1.3e-151 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PMNHDPHM_02214 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMNHDPHM_02215 4.1e-264 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PMNHDPHM_02216 1.9e-178 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMNHDPHM_02217 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
PMNHDPHM_02218 6.2e-58 ftsL D cell division protein FtsL
PMNHDPHM_02219 1.1e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PMNHDPHM_02220 4.8e-78 mraZ K Belongs to the MraZ family
PMNHDPHM_02221 4.2e-53
PMNHDPHM_02222 8.6e-09 S Protein of unknown function (DUF4044)
PMNHDPHM_02223 1.4e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PMNHDPHM_02224 8.6e-153 aatB ET ABC transporter substrate-binding protein
PMNHDPHM_02225 6.9e-113 glnQ 3.6.3.21 E ABC transporter
PMNHDPHM_02226 4.7e-109 artQ P ABC transporter permease
PMNHDPHM_02227 1.1e-141 minD D Belongs to the ParA family
PMNHDPHM_02228 3.7e-114 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
PMNHDPHM_02229 4.7e-83 mreD M rod shape-determining protein MreD
PMNHDPHM_02230 8.5e-151 mreC M Involved in formation and maintenance of cell shape
PMNHDPHM_02231 7.8e-180 mreB D cell shape determining protein MreB
PMNHDPHM_02232 2e-118 radC L DNA repair protein
PMNHDPHM_02233 4.6e-117 S Haloacid dehalogenase-like hydrolase
PMNHDPHM_02234 4.4e-244 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PMNHDPHM_02235 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PMNHDPHM_02237 2.8e-117 rex K CoA binding domain
PMNHDPHM_02238 1.2e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PMNHDPHM_02239 1.4e-217 iscS2 2.8.1.7 E Aminotransferase class V
PMNHDPHM_02240 3.2e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PMNHDPHM_02241 4.1e-86 ytsP 1.8.4.14 T GAF domain-containing protein
PMNHDPHM_02242 2.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PMNHDPHM_02243 0.0 3.6.4.12 L AAA domain
PMNHDPHM_02244 6.5e-93 K Cro/C1-type HTH DNA-binding domain
PMNHDPHM_02245 2e-228 steT E Amino acid permease
PMNHDPHM_02246 1.3e-139 puuD S peptidase C26
PMNHDPHM_02247 7.4e-82
PMNHDPHM_02248 0.0 yhgF K Tex-like protein N-terminal domain protein
PMNHDPHM_02249 3.4e-195 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PMNHDPHM_02252 1.2e-146 ropB K Helix-turn-helix domain
PMNHDPHM_02253 4.2e-77 S CAAX protease self-immunity
PMNHDPHM_02254 0.0 S Bacterial membrane protein YfhO
PMNHDPHM_02255 2.9e-53 yneR S Belongs to the HesB IscA family
PMNHDPHM_02256 2e-115 vraR K helix_turn_helix, Lux Regulon
PMNHDPHM_02257 6.1e-183 vraS 2.7.13.3 T Histidine kinase
PMNHDPHM_02258 2.3e-122 yvqF S Cell wall-active antibiotics response 4TMS YvqF
PMNHDPHM_02259 9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMNHDPHM_02260 1.2e-114 udk 2.7.1.48 F Cytidine monophosphokinase
PMNHDPHM_02261 1e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PMNHDPHM_02262 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PMNHDPHM_02263 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMNHDPHM_02264 6.9e-68 yodB K Transcriptional regulator, HxlR family
PMNHDPHM_02265 5.6e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMNHDPHM_02266 3.3e-138 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMNHDPHM_02267 2.4e-46 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PMNHDPHM_02268 4.5e-180 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMNHDPHM_02269 1.1e-289 arlS 2.7.13.3 T Histidine kinase
PMNHDPHM_02270 7.9e-123 K response regulator
PMNHDPHM_02271 7.2e-272 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PMNHDPHM_02272 1.5e-140 M Peptidase family M23
PMNHDPHM_02273 2.2e-237 L Probable transposase
PMNHDPHM_02274 4.6e-17 yhcX S Psort location Cytoplasmic, score
PMNHDPHM_02276 1.6e-97 yceD S Uncharacterized ACR, COG1399
PMNHDPHM_02277 1.5e-211 ylbM S Belongs to the UPF0348 family
PMNHDPHM_02278 3.1e-141 yqeM Q Methyltransferase
PMNHDPHM_02279 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PMNHDPHM_02280 2.5e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
PMNHDPHM_02281 9.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMNHDPHM_02282 6.4e-48 yhbY J RNA-binding protein
PMNHDPHM_02283 1.8e-217 yqeH S Ribosome biogenesis GTPase YqeH
PMNHDPHM_02284 2.4e-95 yqeG S HAD phosphatase, family IIIA
PMNHDPHM_02285 8e-176 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PMNHDPHM_02286 1.9e-191 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
PMNHDPHM_02287 6.2e-122 mhqD S Dienelactone hydrolase family
PMNHDPHM_02288 2.3e-181 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
PMNHDPHM_02289 1.5e-100 yvdD 3.2.2.10 S Belongs to the LOG family
PMNHDPHM_02290 1.1e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMNHDPHM_02291 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PMNHDPHM_02292 8.9e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PMNHDPHM_02293 6.9e-72 K Transcriptional regulator
PMNHDPHM_02294 3.6e-12 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PMNHDPHM_02295 1.2e-191 mocA S Oxidoreductase
PMNHDPHM_02296 8.4e-51 yiaC K Acetyltransferase (GNAT) domain
PMNHDPHM_02297 9.6e-194 L Transposase and inactivated derivatives, IS30 family
PMNHDPHM_02298 5.3e-80 perR P Belongs to the Fur family
PMNHDPHM_02299 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
PMNHDPHM_02300 5.1e-44 ykuJ S Protein of unknown function (DUF1797)
PMNHDPHM_02301 1.8e-220 patA 2.6.1.1 E Aminotransferase
PMNHDPHM_02302 6.9e-168 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PMNHDPHM_02303 2.7e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
PMNHDPHM_02304 1.5e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PMNHDPHM_02305 2.9e-298 ybeC E amino acid
PMNHDPHM_02306 1.3e-93 sigH K Sigma-70 region 2
PMNHDPHM_02330 4.8e-276 mngB 3.2.1.170 GH38 G hydrolase, family 38
PMNHDPHM_02331 1.5e-255 S Metal-independent alpha-mannosidase (GH125)
PMNHDPHM_02332 2.5e-161 ypbG 2.7.1.2 GK ROK family
PMNHDPHM_02333 2.3e-297 bgl 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PMNHDPHM_02334 3.5e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_02335 6e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
PMNHDPHM_02337 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_02338 2.6e-112 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
PMNHDPHM_02339 1.1e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_02340 1.2e-45 sgcB 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_02341 5.1e-246 G PTS system sugar-specific permease component
PMNHDPHM_02342 7e-225 dgoD 4.2.1.6 M Mandelate racemase muconate lactonizing enzyme
PMNHDPHM_02343 7.7e-90
PMNHDPHM_02344 2.4e-248 ypiB EGP Major facilitator Superfamily
PMNHDPHM_02345 1.8e-72 K Transcriptional regulator
PMNHDPHM_02346 1.2e-76
PMNHDPHM_02347 4.7e-160 K LysR substrate binding domain
PMNHDPHM_02348 7.1e-248 P Sodium:sulfate symporter transmembrane region
PMNHDPHM_02349 3.2e-101 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
PMNHDPHM_02350 4e-289 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
PMNHDPHM_02351 4.5e-149 G PTS system mannose/fructose/sorbose family IID component
PMNHDPHM_02352 1e-129 G PTS system sorbose-specific iic component
PMNHDPHM_02353 3e-162 2.7.1.191 G PTS system sorbose subfamily IIB component
PMNHDPHM_02354 2.9e-256 fucA 3.2.1.51 GH29 G Alpha-L-fucosidase
PMNHDPHM_02355 1.2e-137 K UTRA domain
PMNHDPHM_02356 9.8e-299 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PMNHDPHM_02357 1.1e-130 rpl K Helix-turn-helix domain, rpiR family
PMNHDPHM_02358 2.8e-171 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
PMNHDPHM_02359 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PMNHDPHM_02363 5.1e-89
PMNHDPHM_02364 1.5e-116 ydfK S Protein of unknown function (DUF554)
PMNHDPHM_02365 5.6e-193 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMNHDPHM_02366 9.4e-58
PMNHDPHM_02367 2.4e-47
PMNHDPHM_02369 5.2e-231 EK Aminotransferase, class I
PMNHDPHM_02370 5.8e-166 K LysR substrate binding domain
PMNHDPHM_02371 3.6e-90 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMNHDPHM_02372 9.5e-152 yitU 3.1.3.104 S hydrolase
PMNHDPHM_02373 2.4e-127 yjhF G Phosphoglycerate mutase family
PMNHDPHM_02374 5.7e-121 yoaK S Protein of unknown function (DUF1275)
PMNHDPHM_02375 4.8e-12
PMNHDPHM_02376 1.2e-58
PMNHDPHM_02377 8.1e-143 S hydrolase
PMNHDPHM_02378 4.7e-193 yghZ C Aldo keto reductase family protein
PMNHDPHM_02379 0.0 uvrA3 L excinuclease ABC
PMNHDPHM_02380 7.2e-71 K MarR family
PMNHDPHM_02381 2e-112 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMNHDPHM_02382 2.1e-283 V ABC transporter transmembrane region
PMNHDPHM_02384 1.4e-110 S CAAX protease self-immunity
PMNHDPHM_02385 1.4e-130 ydfF K Transcriptional
PMNHDPHM_02386 4.4e-135 nodI V ABC transporter
PMNHDPHM_02387 8.2e-137 nodJ V ABC-2 type transporter
PMNHDPHM_02388 8.4e-179 shetA P Voltage-dependent anion channel
PMNHDPHM_02389 5.7e-152 rlrG K Transcriptional regulator
PMNHDPHM_02390 0.0 helD 3.6.4.12 L DNA helicase
PMNHDPHM_02391 2.3e-276 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
PMNHDPHM_02392 2e-177 proV E ABC transporter, ATP-binding protein
PMNHDPHM_02393 3.4e-255 gshR 1.8.1.7 C Glutathione reductase
PMNHDPHM_02394 7e-19
PMNHDPHM_02395 3.9e-119 V ATPases associated with a variety of cellular activities
PMNHDPHM_02396 2.6e-39
PMNHDPHM_02397 2.2e-24
PMNHDPHM_02398 4.9e-68
PMNHDPHM_02399 6.3e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMNHDPHM_02400 3.1e-102 lemA S LemA family
PMNHDPHM_02401 6.6e-111 S TPM domain
PMNHDPHM_02402 1.2e-239 dinF V MatE
PMNHDPHM_02403 2.3e-92 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
PMNHDPHM_02404 5.9e-157 bioC 2.1.1.187, 2.1.1.197 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
PMNHDPHM_02405 2e-174 S Aldo keto reductase
PMNHDPHM_02406 4.2e-286 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PMNHDPHM_02407 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PMNHDPHM_02408 2.5e-172 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
PMNHDPHM_02409 3.2e-162 ypuA S Protein of unknown function (DUF1002)
PMNHDPHM_02411 3.8e-98 yxkA S Phosphatidylethanolamine-binding protein
PMNHDPHM_02412 3.3e-172
PMNHDPHM_02413 2.8e-17
PMNHDPHM_02414 5.7e-129 cobB K Sir2 family
PMNHDPHM_02415 1.4e-107 yiiE S Protein of unknown function (DUF1211)
PMNHDPHM_02416 1.5e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PMNHDPHM_02417 3.8e-92 3.6.1.55 F NUDIX domain
PMNHDPHM_02418 1.3e-153 yunF F Protein of unknown function DUF72
PMNHDPHM_02419 1.7e-170 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
PMNHDPHM_02420 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMNHDPHM_02421 1.2e-68
PMNHDPHM_02422 1.1e-30 K Transcriptional
PMNHDPHM_02423 0.0 V ABC transporter
PMNHDPHM_02424 0.0 V ABC transporter
PMNHDPHM_02425 5.6e-169 2.7.13.3 T GHKL domain
PMNHDPHM_02426 7.8e-126 T LytTr DNA-binding domain
PMNHDPHM_02427 1.1e-172 yqhA G Aldose 1-epimerase
PMNHDPHM_02428 3.3e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
PMNHDPHM_02429 5.7e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system
PMNHDPHM_02430 4.7e-148 tatD L hydrolase, TatD family
PMNHDPHM_02431 2.9e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PMNHDPHM_02432 1.3e-157 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PMNHDPHM_02433 1.1e-37 veg S Biofilm formation stimulator VEG
PMNHDPHM_02434 1.4e-164 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PMNHDPHM_02435 6.7e-159 czcD P cation diffusion facilitator family transporter
PMNHDPHM_02436 1.8e-123 ybbM S Uncharacterised protein family (UPF0014)
PMNHDPHM_02437 6.5e-119 ybbL S ABC transporter, ATP-binding protein
PMNHDPHM_02438 1.3e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
PMNHDPHM_02439 7.6e-222 ysaA V RDD family
PMNHDPHM_02440 5.1e-214 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMNHDPHM_02441 1e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMNHDPHM_02442 3.2e-53 nudA S ASCH
PMNHDPHM_02443 2.5e-77
PMNHDPHM_02444 1.4e-60 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PMNHDPHM_02445 2e-178 S DUF218 domain
PMNHDPHM_02446 2.4e-83 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
PMNHDPHM_02447 3.3e-266 ywfO S HD domain protein
PMNHDPHM_02448 4.6e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
PMNHDPHM_02449 3.5e-79 ywiB S Domain of unknown function (DUF1934)
PMNHDPHM_02450 5.9e-62 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PMNHDPHM_02451 8.4e-154 S Protein of unknown function (DUF1211)
PMNHDPHM_02454 8.3e-221 ndh 1.6.99.3 C NADH dehydrogenase
PMNHDPHM_02455 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PMNHDPHM_02456 7.4e-236 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMNHDPHM_02457 3.3e-42 rpmE2 J Ribosomal protein L31
PMNHDPHM_02458 4.7e-73
PMNHDPHM_02459 2e-123
PMNHDPHM_02460 4.6e-125 S Tetratricopeptide repeat
PMNHDPHM_02461 2.3e-147
PMNHDPHM_02462 3e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PMNHDPHM_02463 4.5e-264 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PMNHDPHM_02464 1.7e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PMNHDPHM_02465 6.3e-218 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMNHDPHM_02466 2.4e-37
PMNHDPHM_02467 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
PMNHDPHM_02468 1.9e-07
PMNHDPHM_02469 4.8e-88 S QueT transporter
PMNHDPHM_02470 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
PMNHDPHM_02471 7e-283 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PMNHDPHM_02472 2.7e-131 yciB M ErfK YbiS YcfS YnhG
PMNHDPHM_02473 5.1e-119 S (CBS) domain
PMNHDPHM_02474 6.8e-115 1.6.5.2 S Flavodoxin-like fold
PMNHDPHM_02475 6.1e-250 XK27_06930 S ABC-2 family transporter protein
PMNHDPHM_02476 1.3e-96 padR K Transcriptional regulator PadR-like family
PMNHDPHM_02477 2e-263 S Putative peptidoglycan binding domain
PMNHDPHM_02478 2e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PMNHDPHM_02479 2.1e-102 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PMNHDPHM_02480 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMNHDPHM_02481 2.9e-282 yabM S Polysaccharide biosynthesis protein
PMNHDPHM_02482 1.8e-38 yabO J S4 domain protein
PMNHDPHM_02483 4.4e-65 divIC D cell cycle
PMNHDPHM_02484 4.7e-82 yabR J RNA binding
PMNHDPHM_02485 4.8e-246 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PMNHDPHM_02486 5.9e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PMNHDPHM_02487 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMNHDPHM_02488 3.8e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PMNHDPHM_02489 2.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMNHDPHM_02490 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PMNHDPHM_02491 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
PMNHDPHM_02492 4.4e-106 S Domain of unknown function (DUF1788)
PMNHDPHM_02493 1.4e-104 S Putative inner membrane protein (DUF1819)
PMNHDPHM_02494 1.8e-212 ykiI
PMNHDPHM_02495 0.0 pip V domain protein
PMNHDPHM_02496 6.6e-246 scrA 2.7.1.211 G phosphotransferase system
PMNHDPHM_02497 6e-103 pts26BCA 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
PMNHDPHM_02498 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
PMNHDPHM_02499 1.4e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
PMNHDPHM_02500 8.2e-303 scrB 3.2.1.26 GH32 G invertase
PMNHDPHM_02502 4.9e-162 azoB GM NmrA-like family
PMNHDPHM_02503 1.3e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
PMNHDPHM_02504 9.1e-144 accA 2.1.3.15, 6.4.1.2 I alpha subunit
PMNHDPHM_02505 1e-153 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PMNHDPHM_02506 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
PMNHDPHM_02507 1.2e-76 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PMNHDPHM_02508 2.3e-51 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PMNHDPHM_02509 6.3e-224 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PMNHDPHM_02510 7.3e-127 IQ reductase
PMNHDPHM_02511 2.7e-166 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PMNHDPHM_02512 2.4e-173 fabK 1.3.1.9 S Nitronate monooxygenase
PMNHDPHM_02513 4.5e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PMNHDPHM_02514 1.5e-175 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PMNHDPHM_02515 2.1e-76 marR K Winged helix DNA-binding domain
PMNHDPHM_02516 9e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
PMNHDPHM_02517 5.1e-192 I carboxylic ester hydrolase activity
PMNHDPHM_02518 4.9e-229 bdhA C Iron-containing alcohol dehydrogenase
PMNHDPHM_02519 4.9e-63 P Rhodanese-like domain
PMNHDPHM_02520 3.1e-84 yetL K helix_turn_helix multiple antibiotic resistance protein
PMNHDPHM_02521 4.3e-26
PMNHDPHM_02522 1.3e-67 K MarR family
PMNHDPHM_02523 4.1e-11 S response to antibiotic
PMNHDPHM_02524 6.7e-171 S Putative esterase
PMNHDPHM_02525 4e-185
PMNHDPHM_02526 1.1e-104 rmaB K Transcriptional regulator, MarR family
PMNHDPHM_02527 2.8e-87 F NUDIX domain
PMNHDPHM_02528 3.5e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMNHDPHM_02529 3.4e-29
PMNHDPHM_02530 8.6e-129 S zinc-ribbon domain
PMNHDPHM_02531 9.4e-203 pbpX1 V Beta-lactamase
PMNHDPHM_02532 1.5e-181 K AI-2E family transporter
PMNHDPHM_02533 1.1e-127 srtA 3.4.22.70 M Sortase family
PMNHDPHM_02534 1.5e-65 gtcA S Teichoic acid glycosylation protein
PMNHDPHM_02535 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PMNHDPHM_02536 1.5e-169 gbuC E glycine betaine
PMNHDPHM_02537 9.4e-126 proW E glycine betaine
PMNHDPHM_02538 1e-221 gbuA 3.6.3.32 E glycine betaine
PMNHDPHM_02539 1.1e-135 sfsA S Belongs to the SfsA family
PMNHDPHM_02540 1.5e-172
PMNHDPHM_02541 1.9e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PMNHDPHM_02542 9.7e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
PMNHDPHM_02543 5.2e-240 ytoI K DRTGG domain
PMNHDPHM_02544 1.1e-206 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PMNHDPHM_02545 4.7e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMNHDPHM_02546 3.9e-116 sirR K Helix-turn-helix diphteria tox regulatory element
PMNHDPHM_02547 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PMNHDPHM_02548 2.1e-49 yajC U Preprotein translocase
PMNHDPHM_02549 1e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PMNHDPHM_02550 9.5e-208 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PMNHDPHM_02551 6.2e-196 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PMNHDPHM_02552 3.9e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PMNHDPHM_02553 3.5e-103 yjbF S SNARE associated Golgi protein
PMNHDPHM_02554 1.6e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PMNHDPHM_02555 1.4e-222 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
PMNHDPHM_02556 3.5e-74 S Protein of unknown function (DUF3290)
PMNHDPHM_02557 1.2e-117 yviA S Protein of unknown function (DUF421)
PMNHDPHM_02558 1.1e-163 S Alpha beta hydrolase
PMNHDPHM_02559 1.1e-120
PMNHDPHM_02560 4.1e-158 dkgB S reductase
PMNHDPHM_02561 1.3e-84 nrdI F Belongs to the NrdI family
PMNHDPHM_02562 1.6e-179 D Alpha beta
PMNHDPHM_02563 1.5e-77 K Transcriptional regulator
PMNHDPHM_02564 5.4e-121 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
PMNHDPHM_02565 3.6e-197 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
PMNHDPHM_02566 3.4e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PMNHDPHM_02567 1.8e-59
PMNHDPHM_02568 1.7e-181 3.4.11.5 I Releases the N-terminal proline from various substrates
PMNHDPHM_02569 0.0 yfgQ P E1-E2 ATPase
PMNHDPHM_02570 2.2e-60
PMNHDPHM_02571 5e-78 ndk 2.7.4.6 F Belongs to the NDK family
PMNHDPHM_02572 0.0 pepF E Oligopeptidase F
PMNHDPHM_02573 1.1e-289 V ABC transporter transmembrane region
PMNHDPHM_02574 2.7e-177 K sequence-specific DNA binding
PMNHDPHM_02575 8.1e-96
PMNHDPHM_02576 8.3e-90 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PMNHDPHM_02577 1.1e-170 mleP S Sodium Bile acid symporter family
PMNHDPHM_02578 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
PMNHDPHM_02579 2.2e-162 mleR K LysR family
PMNHDPHM_02580 1.7e-173 corA P CorA-like Mg2+ transporter protein
PMNHDPHM_02581 4e-62 yeaO S Protein of unknown function, DUF488
PMNHDPHM_02582 1.4e-104 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PMNHDPHM_02583 7.2e-98
PMNHDPHM_02584 1.4e-107 ywrF S Flavin reductase like domain
PMNHDPHM_02585 2.9e-168 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PMNHDPHM_02586 5.3e-78
PMNHDPHM_02587 1e-97 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMNHDPHM_02588 7.4e-26
PMNHDPHM_02589 2.3e-207 yubA S AI-2E family transporter
PMNHDPHM_02590 3.4e-80
PMNHDPHM_02591 3.4e-56
PMNHDPHM_02592 5.9e-191 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
PMNHDPHM_02593 6.6e-50
PMNHDPHM_02594 7.5e-25 ygbF S Sugar efflux transporter for intercellular exchange
PMNHDPHM_02595 6.3e-57 K Transcriptional regulator PadR-like family
PMNHDPHM_02596 2.1e-185 K sequence-specific DNA binding
PMNHDPHM_02599 5.7e-208 lctO C IMP dehydrogenase / GMP reductase domain
PMNHDPHM_02600 2.6e-123 drgA C Nitroreductase family
PMNHDPHM_02601 9.3e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
PMNHDPHM_02602 1.4e-161 ptlF S KR domain
PMNHDPHM_02603 8.9e-281 QT PucR C-terminal helix-turn-helix domain
PMNHDPHM_02604 1.7e-67 yqkB S Belongs to the HesB IscA family
PMNHDPHM_02605 1.2e-241 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PMNHDPHM_02606 1.3e-128 K cheY-homologous receiver domain
PMNHDPHM_02607 1.1e-10
PMNHDPHM_02608 6.4e-72 S GtrA-like protein
PMNHDPHM_02609 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
PMNHDPHM_02610 9.6e-183 ykcC GT2 M Glycosyl transferase family 2
PMNHDPHM_02611 9.3e-29
PMNHDPHM_02612 1.1e-186 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
PMNHDPHM_02613 2.3e-281 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
PMNHDPHM_02614 1.5e-91 yhbO 3.5.1.124 S DJ-1/PfpI family
PMNHDPHM_02615 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PMNHDPHM_02616 1.1e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PMNHDPHM_02617 2.7e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PMNHDPHM_02618 4.2e-74 ssb_2 L Single-strand binding protein family
PMNHDPHM_02620 3.1e-15
PMNHDPHM_02623 4.7e-08 ssb_2 L Single-strand binding protein family
PMNHDPHM_02624 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMNHDPHM_02625 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMNHDPHM_02626 3.3e-203 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMNHDPHM_02627 2e-32 yaaA S S4 domain protein YaaA
PMNHDPHM_02628 2.7e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PMNHDPHM_02629 3.5e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMNHDPHM_02630 5e-276 L PFAM Integrase core domain
PMNHDPHM_02631 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PMNHDPHM_02633 1.9e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PMNHDPHM_02634 6.4e-138 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PMNHDPHM_02635 1.9e-138 jag S R3H domain protein
PMNHDPHM_02636 1.3e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PMNHDPHM_02637 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PMNHDPHM_02638 3.8e-277 V ABC transporter transmembrane region
PMNHDPHM_02639 1.3e-31
PMNHDPHM_02641 1.9e-133 thrE S Putative threonine/serine exporter
PMNHDPHM_02642 2.6e-80 S Threonine/Serine exporter, ThrE
PMNHDPHM_02643 6e-227 amd 3.5.1.47 E Peptidase family M20/M25/M40
PMNHDPHM_02646 6.2e-199 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
PMNHDPHM_02649 5.4e-150 M NLPA lipoprotein
PMNHDPHM_02650 7.5e-146 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
PMNHDPHM_02651 5.5e-225 mtnE 2.6.1.83 E Aminotransferase
PMNHDPHM_02652 0.0 M Leucine rich repeats (6 copies)
PMNHDPHM_02653 3.2e-183
PMNHDPHM_02654 4.7e-208 bacI V MacB-like periplasmic core domain
PMNHDPHM_02655 2e-126 V ABC transporter
PMNHDPHM_02656 9.6e-152 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PMNHDPHM_02657 7.2e-225 spiA K IrrE N-terminal-like domain
PMNHDPHM_02658 5.2e-139
PMNHDPHM_02659 1.7e-16
PMNHDPHM_02660 2.8e-44
PMNHDPHM_02661 8.6e-150 S haloacid dehalogenase-like hydrolase
PMNHDPHM_02662 9.6e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PMNHDPHM_02663 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
PMNHDPHM_02664 0.0 mtlR K Mga helix-turn-helix domain
PMNHDPHM_02665 1e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PMNHDPHM_02666 1.2e-216 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
PMNHDPHM_02667 5.9e-185 lipA I Carboxylesterase family
PMNHDPHM_02668 1.5e-180 D Alpha beta
PMNHDPHM_02669 8.8e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMNHDPHM_02671 2.2e-14 ytgB S Transglycosylase associated protein
PMNHDPHM_02672 2.9e-16
PMNHDPHM_02673 5.6e-13 S Phage head-tail joining protein
PMNHDPHM_02674 1.7e-47 S Phage gp6-like head-tail connector protein
PMNHDPHM_02675 4.3e-294 S Phage capsid family
PMNHDPHM_02676 4.7e-224 S Phage portal protein
PMNHDPHM_02677 2.1e-22
PMNHDPHM_02678 0.0 terL S overlaps another CDS with the same product name
PMNHDPHM_02679 9.6e-80 terS L Phage terminase, small subunit
PMNHDPHM_02680 9.8e-76 L Phage-associated protein
PMNHDPHM_02681 4.7e-78
PMNHDPHM_02682 1.9e-280 S Virulence-associated protein E
PMNHDPHM_02683 3.9e-161 L Bifunctional DNA primase/polymerase, N-terminal
PMNHDPHM_02684 2.1e-25
PMNHDPHM_02685 5e-41
PMNHDPHM_02686 1.8e-29
PMNHDPHM_02687 8.7e-18
PMNHDPHM_02688 2.3e-31
PMNHDPHM_02689 3.2e-43
PMNHDPHM_02690 7.3e-11 K TRANSCRIPTIONal
PMNHDPHM_02691 8.3e-108 K sequence-specific DNA binding
PMNHDPHM_02692 9.2e-225 sip L Belongs to the 'phage' integrase family
PMNHDPHM_02693 6.8e-170 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
PMNHDPHM_02694 5.4e-132 yfeJ 6.3.5.2 F Glutamine amidotransferase class-I
PMNHDPHM_02695 1.4e-68
PMNHDPHM_02696 1e-151 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
PMNHDPHM_02698 1.7e-99
PMNHDPHM_02699 9.6e-121 dpiA KT cheY-homologous receiver domain
PMNHDPHM_02700 3.2e-273 dcuS 2.7.13.3 T Single cache domain 3
PMNHDPHM_02701 1.5e-223 maeN C 2-hydroxycarboxylate transporter family
PMNHDPHM_02702 2e-65 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PMNHDPHM_02703 1.5e-124 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
PMNHDPHM_02706 2.1e-57 yjdF S Protein of unknown function (DUF2992)
PMNHDPHM_02707 1.3e-113 S Bacteriocin-protection, YdeI or OmpD-Associated
PMNHDPHM_02708 1.2e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
PMNHDPHM_02709 7.1e-124
PMNHDPHM_02710 2.5e-121 K response regulator
PMNHDPHM_02711 1.2e-219 hpk31 2.7.13.3 T Histidine kinase
PMNHDPHM_02712 1.3e-238 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PMNHDPHM_02713 1.2e-85 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMNHDPHM_02714 2.7e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMNHDPHM_02715 5.4e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
PMNHDPHM_02716 2.1e-165 yvgN C Aldo keto reductase
PMNHDPHM_02717 8.7e-142 iolR K DeoR C terminal sensor domain
PMNHDPHM_02718 2.3e-268 iolT EGP Major facilitator Superfamily
PMNHDPHM_02719 9.5e-275 iolA 1.2.1.18, 1.2.1.27 C Belongs to the aldehyde dehydrogenase family
PMNHDPHM_02720 7.6e-157 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
PMNHDPHM_02721 3.8e-179 iolC 2.7.1.92 H Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
PMNHDPHM_02722 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
PMNHDPHM_02723 1.1e-192 iolG 1.1.1.18, 1.1.1.369 C Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
PMNHDPHM_02724 1.8e-195 iolG2 1.1.1.18, 1.1.1.369 S Oxidoreductase family, C-terminal alpha/beta domain
PMNHDPHM_02725 3.6e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
PMNHDPHM_02726 3e-159 iolJ 4.1.2.13, 4.1.2.29 G Fructose-bisphosphate aldolase class-II
PMNHDPHM_02727 1.7e-66 iolK S Tautomerase enzyme
PMNHDPHM_02728 1.4e-161 iolI 5.3.99.11 G Xylose isomerase-like TIM barrel
PMNHDPHM_02729 3.4e-171 iolH G Xylose isomerase-like TIM barrel
PMNHDPHM_02730 1.5e-147 gntR K rpiR family
PMNHDPHM_02731 1.6e-169 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
PMNHDPHM_02732 2.1e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
PMNHDPHM_02733 3.5e-207 gntP EG Gluconate
PMNHDPHM_02734 1.1e-253 S O-antigen ligase like membrane protein
PMNHDPHM_02735 2.8e-151 S Glycosyl transferase family 2
PMNHDPHM_02736 2.4e-127 welB S Glycosyltransferase like family 2
PMNHDPHM_02737 4.5e-191 rgpB GT2 M Glycosyl transferase family 2
PMNHDPHM_02738 1.8e-262 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
PMNHDPHM_02739 1.2e-196 S Protein conserved in bacteria
PMNHDPHM_02740 2e-58
PMNHDPHM_02741 4.1e-130 fhuC 3.6.3.35 P ABC transporter
PMNHDPHM_02742 3e-134 znuB U ABC 3 transport family
PMNHDPHM_02743 1.7e-167 T Calcineurin-like phosphoesterase superfamily domain
PMNHDPHM_02744 5.8e-163 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
PMNHDPHM_02745 0.0 pepF E oligoendopeptidase F
PMNHDPHM_02746 2e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
PMNHDPHM_02747 2.3e-246 brnQ U Component of the transport system for branched-chain amino acids
PMNHDPHM_02748 7.4e-73 T Sh3 type 3 domain protein
PMNHDPHM_02749 2.2e-134 glcR K DeoR C terminal sensor domain
PMNHDPHM_02750 8.9e-147 M Glycosyltransferase like family 2
PMNHDPHM_02751 4.8e-134 XK27_06755 S Protein of unknown function (DUF975)
PMNHDPHM_02752 2.6e-53
PMNHDPHM_02753 2e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMNHDPHM_02754 1.4e-175 draG O ADP-ribosylglycohydrolase
PMNHDPHM_02755 1.5e-294 S ABC transporter
PMNHDPHM_02756 2.6e-140 ksgA 2.1.1.182, 2.1.1.197, 2.5.1.134 J rRNA (adenine-N6,N6-)-dimethyltransferase activity
PMNHDPHM_02759 1.3e-96 2.3.1.128, 5.2.1.8 J Acetyltransferase (GNAT) domain
PMNHDPHM_02761 5.5e-127 V ATPases associated with a variety of cellular activities
PMNHDPHM_02762 1.9e-55
PMNHDPHM_02763 3.1e-150 recO L Involved in DNA repair and RecF pathway recombination
PMNHDPHM_02764 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMNHDPHM_02765 1.8e-63 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PMNHDPHM_02766 1.5e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PMNHDPHM_02767 8.2e-84 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PMNHDPHM_02768 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
PMNHDPHM_02769 1.6e-68 yqeY S YqeY-like protein
PMNHDPHM_02770 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PMNHDPHM_02771 7.2e-155 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
PMNHDPHM_02772 1.1e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
PMNHDPHM_02773 4.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
PMNHDPHM_02774 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
PMNHDPHM_02775 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PMNHDPHM_02776 4.9e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
PMNHDPHM_02777 3e-276
PMNHDPHM_02778 1.6e-160 V ABC transporter
PMNHDPHM_02779 1.2e-82 FG adenosine 5'-monophosphoramidase activity
PMNHDPHM_02780 2.3e-248 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
PMNHDPHM_02781 3.4e-117 3.1.3.18 J HAD-hyrolase-like
PMNHDPHM_02782 3.6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PMNHDPHM_02783 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMNHDPHM_02784 3.7e-54
PMNHDPHM_02785 7e-130 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PMNHDPHM_02786 3.5e-174 prmA J Ribosomal protein L11 methyltransferase
PMNHDPHM_02787 3.6e-85 XK27_03960 S Protein of unknown function (DUF3013)
PMNHDPHM_02788 3.2e-112 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
PMNHDPHM_02789 3.1e-37
PMNHDPHM_02790 2.7e-64 S Protein of unknown function (DUF1093)
PMNHDPHM_02791 2.3e-26
PMNHDPHM_02792 5.7e-62
PMNHDPHM_02794 9.2e-112 1.6.5.2 S Flavodoxin-like fold
PMNHDPHM_02795 2.1e-94 K Bacterial regulatory proteins, tetR family
PMNHDPHM_02796 9.1e-267 L Transposase DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)