ORF_ID e_value Gene_name EC_number CAZy COGs Description
HCONIBLK_00001 1e-303 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HCONIBLK_00002 0.0 lacZ3 3.2.1.23 G Beta-galactosidase trimerisation domain
HCONIBLK_00003 3.1e-218 blt G MFS/sugar transport protein
HCONIBLK_00004 2.8e-122 K Bacterial regulatory proteins, tetR family
HCONIBLK_00005 1e-84 dps P Belongs to the Dps family
HCONIBLK_00006 9.1e-248 ytfL P Transporter associated domain
HCONIBLK_00007 2.2e-128 cah 4.2.1.1 P Reversible hydration of carbon dioxide
HCONIBLK_00008 2.4e-214 K helix_turn _helix lactose operon repressor
HCONIBLK_00009 2e-35
HCONIBLK_00010 2.4e-159 xylG 3.6.3.17 G ATPases associated with a variety of cellular activities
HCONIBLK_00011 1.5e-53
HCONIBLK_00012 1.5e-194 K helix_turn _helix lactose operon repressor
HCONIBLK_00013 8.5e-311 3.2.1.55 GH51 G arabinose metabolic process
HCONIBLK_00014 7.4e-305 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HCONIBLK_00015 5.1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
HCONIBLK_00016 1.9e-299 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HCONIBLK_00017 9.1e-169 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
HCONIBLK_00018 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HCONIBLK_00019 2.5e-298 yjjP S Threonine/Serine exporter, ThrE
HCONIBLK_00020 1.4e-270 G Psort location CytoplasmicMembrane, score 10.00
HCONIBLK_00021 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
HCONIBLK_00022 9.9e-202 K Periplasmic binding protein domain
HCONIBLK_00023 1.2e-145 cobB2 K Sir2 family
HCONIBLK_00024 2.8e-224 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
HCONIBLK_00025 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
HCONIBLK_00027 9.1e-186 K Psort location Cytoplasmic, score
HCONIBLK_00028 0.0 rafA 3.2.1.22 G Raffinose synthase or seed imbibition protein Sip1
HCONIBLK_00029 1.5e-161 G Binding-protein-dependent transport system inner membrane component
HCONIBLK_00030 6.8e-184 G Binding-protein-dependent transport system inner membrane component
HCONIBLK_00031 4.2e-231 msmE7 G Bacterial extracellular solute-binding protein
HCONIBLK_00032 3.6e-232 nagC GK ROK family
HCONIBLK_00033 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
HCONIBLK_00034 5.7e-85 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HCONIBLK_00035 0.0 yjcE P Sodium/hydrogen exchanger family
HCONIBLK_00036 3.6e-171 ypfH S Phospholipase/Carboxylesterase
HCONIBLK_00037 7.9e-163 D nuclear chromosome segregation
HCONIBLK_00038 6.9e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
HCONIBLK_00039 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
HCONIBLK_00040 2.6e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCONIBLK_00041 3.6e-279 KLT Domain of unknown function (DUF4032)
HCONIBLK_00042 1.5e-211 ugpC E Belongs to the ABC transporter superfamily
HCONIBLK_00043 5.5e-189 U Ion channel
HCONIBLK_00044 0.0 KLT Protein tyrosine kinase
HCONIBLK_00045 5.8e-85 O Thioredoxin
HCONIBLK_00047 1.2e-219 S G5
HCONIBLK_00048 7e-164 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HCONIBLK_00049 4.1e-178 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HCONIBLK_00050 1.5e-112 S LytR cell envelope-related transcriptional attenuator
HCONIBLK_00051 1.4e-308 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
HCONIBLK_00052 3.5e-172 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
HCONIBLK_00053 0.0
HCONIBLK_00054 0.0 murJ KLT MviN-like protein
HCONIBLK_00055 1.3e-179 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HCONIBLK_00056 1.9e-232 parB K Belongs to the ParB family
HCONIBLK_00057 8.7e-176 parA D CobQ CobB MinD ParA nucleotide binding domain protein
HCONIBLK_00058 8.8e-136 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HCONIBLK_00059 3.2e-95 jag S Putative single-stranded nucleic acids-binding domain
HCONIBLK_00060 5.6e-178 yidC U Membrane protein insertase, YidC Oxa1 family
HCONIBLK_00061 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HCONIBLK_00062 0.0 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HCONIBLK_00063 1.9e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HCONIBLK_00064 9.2e-267 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HCONIBLK_00065 5.8e-91 S Protein of unknown function (DUF721)
HCONIBLK_00066 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCONIBLK_00067 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HCONIBLK_00068 6.2e-75 S Transmembrane domain of unknown function (DUF3566)
HCONIBLK_00069 1.8e-217 V VanZ like family
HCONIBLK_00070 1.9e-161 yplQ S Haemolysin-III related
HCONIBLK_00071 5.8e-263 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
HCONIBLK_00072 2e-236 EGP Major facilitator Superfamily
HCONIBLK_00073 8.8e-162 3.2.1.78 GH26 G Glycosyl hydrolase family 26
HCONIBLK_00074 4e-68 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HCONIBLK_00075 3.5e-51 gcs2 S A circularly permuted ATPgrasp
HCONIBLK_00078 2.4e-144 S Protein of unknown function DUF45
HCONIBLK_00079 8.1e-78
HCONIBLK_00080 1.6e-154 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HCONIBLK_00081 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HCONIBLK_00082 1.1e-149 ybaJ Q ubiE/COQ5 methyltransferase family
HCONIBLK_00083 7.7e-166
HCONIBLK_00084 2e-106 XK27_04590 S NADPH-dependent FMN reductase
HCONIBLK_00085 8e-120
HCONIBLK_00086 2.1e-22
HCONIBLK_00089 4.7e-57 mazG S MazG-like family
HCONIBLK_00090 4.4e-26 L Uncharacterized conserved protein (DUF2075)
HCONIBLK_00092 3.1e-194 sinIM 2.1.1.37 H C-5 cytosine-specific DNA methylase
HCONIBLK_00093 2e-47 S Type II restriction endonuclease EcoO109I
HCONIBLK_00094 0.0
HCONIBLK_00095 3.4e-111
HCONIBLK_00096 0.0
HCONIBLK_00097 2.8e-287
HCONIBLK_00098 3.4e-38 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HCONIBLK_00099 2.6e-34 chpA T Toxic component of a toxin-antitoxin (TA) module
HCONIBLK_00100 4.5e-67 chpA T Toxic component of a toxin-antitoxin (TA) module
HCONIBLK_00101 3.7e-165 K Bacterial regulatory helix-turn-helix protein, lysR family
HCONIBLK_00102 1.4e-24 akr5f 1.1.1.346 S reductase
HCONIBLK_00103 1.4e-121 akr5f 1.1.1.346 S Aldo/keto reductase family
HCONIBLK_00104 0.0 bglB 3.2.1.21 GH3 G Glycosyl hydrolase family 3 N-terminal domain protein
HCONIBLK_00105 3.6e-84 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
HCONIBLK_00106 5.8e-21 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
HCONIBLK_00107 1.3e-87 S Domain of unknown function (DUF4234)
HCONIBLK_00109 2.5e-62 murJ KLT MviN-like protein
HCONIBLK_00110 1.8e-38 lhr L Helicase
HCONIBLK_00111 7.8e-29 lhr L Helicase
HCONIBLK_00112 1.9e-183 E ABC transporter, substrate-binding protein, family 5
HCONIBLK_00113 1.4e-124 amyE G Bacterial extracellular solute-binding protein
HCONIBLK_00114 4.1e-189 tnpA L Transposase
HCONIBLK_00115 1.2e-205 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCONIBLK_00116 1.2e-47 S Protein of unknown function (DUF3073)
HCONIBLK_00117 1.4e-80 I Sterol carrier protein
HCONIBLK_00118 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HCONIBLK_00119 5.4e-36
HCONIBLK_00120 5.7e-129 gluP 3.4.21.105 S Rhomboid family
HCONIBLK_00121 2.2e-284 L ribosomal rna small subunit methyltransferase
HCONIBLK_00122 7.2e-37 crgA D Involved in cell division
HCONIBLK_00123 3.3e-141 S Bacterial protein of unknown function (DUF881)
HCONIBLK_00124 9.2e-225 srtA 3.4.22.70 M Sortase family
HCONIBLK_00125 3.1e-121 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
HCONIBLK_00126 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
HCONIBLK_00127 1.3e-193 T Protein tyrosine kinase
HCONIBLK_00128 2.2e-271 pbpA M penicillin-binding protein
HCONIBLK_00129 1.1e-290 rodA D Belongs to the SEDS family
HCONIBLK_00130 7.6e-267 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
HCONIBLK_00131 8e-62 fhaB T Inner membrane component of T3SS, cytoplasmic domain
HCONIBLK_00132 2.3e-130 fhaA T Protein of unknown function (DUF2662)
HCONIBLK_00133 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
HCONIBLK_00134 4.7e-127 yicL EG EamA-like transporter family
HCONIBLK_00135 3.1e-214 pldB 3.1.1.5 I Serine aminopeptidase, S33
HCONIBLK_00136 5.7e-58
HCONIBLK_00137 2.6e-180 rrmA 2.1.1.187 Q Methyltransferase domain
HCONIBLK_00138 3.1e-32 ytgB S Transglycosylase associated protein
HCONIBLK_00139 2.4e-29 ymgJ S Transglycosylase associated protein
HCONIBLK_00141 1.6e-279 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HCONIBLK_00142 0.0 cadA P E1-E2 ATPase
HCONIBLK_00143 1.9e-285 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
HCONIBLK_00144 1.1e-115 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCONIBLK_00145 8.8e-308 S Sel1-like repeats.
HCONIBLK_00146 4.6e-279 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HCONIBLK_00148 3.8e-179 htpX O Belongs to the peptidase M48B family
HCONIBLK_00149 4.8e-213 lppW 3.5.2.6 V Beta-lactamase
HCONIBLK_00150 2.5e-123 E SOS response associated peptidase (SRAP)
HCONIBLK_00151 1.1e-228 araJ EGP Major facilitator Superfamily
HCONIBLK_00152 1.1e-11 S NADPH-dependent FMN reductase
HCONIBLK_00153 7.7e-52 relB L RelB antitoxin
HCONIBLK_00154 4.9e-87 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HCONIBLK_00155 1.7e-270 2.7.11.1 S cellulose binding
HCONIBLK_00156 1.1e-141 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCONIBLK_00157 1.3e-86 4.1.1.44 S Cupin domain
HCONIBLK_00158 8.2e-190 S Dienelactone hydrolase family
HCONIBLK_00159 8.3e-162 K Bacterial regulatory helix-turn-helix protein, lysR family
HCONIBLK_00160 8.8e-195 C Aldo/keto reductase family
HCONIBLK_00162 3.8e-251 P nitric oxide dioxygenase activity
HCONIBLK_00163 9.3e-89 C Flavodoxin
HCONIBLK_00164 6.3e-40 K helix_turn_helix, mercury resistance
HCONIBLK_00165 5.9e-85 fldA C Flavodoxin
HCONIBLK_00166 6.9e-147 GM NmrA-like family
HCONIBLK_00167 7.4e-205 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
HCONIBLK_00168 2e-166 K LysR substrate binding domain
HCONIBLK_00169 3.7e-254 3.5.1.104 G Polysaccharide deacetylase
HCONIBLK_00170 3e-195 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
HCONIBLK_00171 2.2e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HCONIBLK_00172 1.2e-174 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCONIBLK_00173 6.5e-63 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCONIBLK_00174 3e-233 U Belongs to the binding-protein-dependent transport system permease family
HCONIBLK_00175 9.7e-159 livM U Belongs to the binding-protein-dependent transport system permease family
HCONIBLK_00176 5.3e-160 natA E Branched-chain amino acid ATP-binding cassette transporter
HCONIBLK_00177 1.6e-151 livF E ATPases associated with a variety of cellular activities
HCONIBLK_00178 1.1e-215 natB E Receptor family ligand binding region
HCONIBLK_00179 4.8e-193 K helix_turn _helix lactose operon repressor
HCONIBLK_00180 7.4e-299 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
HCONIBLK_00181 2.4e-295 G Transporter major facilitator family protein
HCONIBLK_00182 6.3e-107 natB E Receptor family ligand binding region
HCONIBLK_00183 8.4e-243 bccA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Biotin carboxylase C-terminal domain
HCONIBLK_00184 1.9e-183 4.2.1.48 S Domain of unknown function (DUF4392)
HCONIBLK_00185 2.3e-279 scrT G Transporter major facilitator family protein
HCONIBLK_00186 4.8e-93 S Acetyltransferase (GNAT) family
HCONIBLK_00187 2.7e-48 S Protein of unknown function (DUF1778)
HCONIBLK_00188 3.9e-15
HCONIBLK_00189 3.8e-257 yhjE EGP Sugar (and other) transporter
HCONIBLK_00190 1.1e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HCONIBLK_00191 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
HCONIBLK_00192 6.5e-220 E GDSL-like Lipase/Acylhydrolase family
HCONIBLK_00193 8e-284 bglA 3.2.1.21 G Glycosyl hydrolase family 1
HCONIBLK_00194 1e-136 G beta-mannosidase
HCONIBLK_00195 5.2e-187 K helix_turn _helix lactose operon repressor
HCONIBLK_00196 3.4e-112 S Protein of unknown function, DUF624
HCONIBLK_00197 8.9e-133
HCONIBLK_00198 3e-25
HCONIBLK_00199 3.3e-260 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
HCONIBLK_00200 3.1e-133 ybbL V ATPases associated with a variety of cellular activities
HCONIBLK_00201 1.9e-145 ybbM V Uncharacterised protein family (UPF0014)
HCONIBLK_00202 6e-277 aroP E aromatic amino acid transport protein AroP K03293
HCONIBLK_00203 1.1e-127 V ABC transporter
HCONIBLK_00204 0.0 V FtsX-like permease family
HCONIBLK_00205 6.4e-282 cycA E Amino acid permease
HCONIBLK_00206 4.6e-33 V efflux transmembrane transporter activity
HCONIBLK_00207 2.8e-19 MV MacB-like periplasmic core domain
HCONIBLK_00208 4.6e-305 M MacB-like periplasmic core domain
HCONIBLK_00209 9.3e-74 V ABC transporter, ATP-binding protein
HCONIBLK_00210 1.2e-106 ydgJ K helix_turn_helix multiple antibiotic resistance protein
HCONIBLK_00211 0.0 lmrA1 V ABC transporter, ATP-binding protein
HCONIBLK_00212 0.0 lmrA2 V ABC transporter transmembrane region
HCONIBLK_00213 4e-268 xynD 3.2.1.8, 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
HCONIBLK_00214 6e-123 3.6.1.27 I Acid phosphatase homologues
HCONIBLK_00215 1.6e-114 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HCONIBLK_00216 2.7e-73
HCONIBLK_00217 3.7e-219 natB E Receptor family ligand binding region
HCONIBLK_00218 9.5e-102 K Psort location Cytoplasmic, score 8.87
HCONIBLK_00219 0.0 pip S YhgE Pip domain protein
HCONIBLK_00220 0.0 pip S YhgE Pip domain protein
HCONIBLK_00221 2.5e-107 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
HCONIBLK_00222 3.4e-132 XK26_04485 P Cobalt transport protein
HCONIBLK_00223 6.2e-282 G ATPases associated with a variety of cellular activities
HCONIBLK_00224 7.7e-182 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HCONIBLK_00225 3.9e-167 S esterase of the alpha-beta hydrolase superfamily
HCONIBLK_00226 5e-142 S esterase of the alpha-beta hydrolase superfamily
HCONIBLK_00227 1.2e-94
HCONIBLK_00229 2e-310 pepD E Peptidase family C69
HCONIBLK_00230 3.3e-121 icaR K Bacterial regulatory proteins, tetR family
HCONIBLK_00231 1.5e-224 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HCONIBLK_00232 9e-237 amt U Ammonium Transporter Family
HCONIBLK_00233 4.5e-55 glnB K Nitrogen regulatory protein P-II
HCONIBLK_00234 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
HCONIBLK_00235 2.4e-38 K sequence-specific DNA binding
HCONIBLK_00236 9.8e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HCONIBLK_00237 1.8e-284 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
HCONIBLK_00238 9.7e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
HCONIBLK_00239 1.7e-52 S granule-associated protein
HCONIBLK_00240 0.0 ubiB S ABC1 family
HCONIBLK_00241 1.1e-200 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HCONIBLK_00242 1e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HCONIBLK_00243 2e-129
HCONIBLK_00244 7.3e-205 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
HCONIBLK_00245 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HCONIBLK_00246 9.6e-78 cpaE D bacterial-type flagellum organization
HCONIBLK_00247 1.3e-229 cpaF U Type II IV secretion system protein
HCONIBLK_00248 2.9e-107 U Type ii secretion system
HCONIBLK_00249 3.7e-111 U Type II secretion system (T2SS), protein F
HCONIBLK_00250 1.7e-39 S Protein of unknown function (DUF4244)
HCONIBLK_00251 6.5e-50 U TadE-like protein
HCONIBLK_00252 2.5e-75 S TIGRFAM helicase secretion neighborhood TadE-like protein
HCONIBLK_00253 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
HCONIBLK_00254 6.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HCONIBLK_00255 6.9e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
HCONIBLK_00256 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
HCONIBLK_00257 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HCONIBLK_00258 5.4e-121
HCONIBLK_00259 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HCONIBLK_00260 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HCONIBLK_00261 5.9e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HCONIBLK_00262 4.1e-10 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
HCONIBLK_00263 3.2e-220 3.6.1.27 I PAP2 superfamily
HCONIBLK_00264 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HCONIBLK_00265 2e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HCONIBLK_00266 5e-211 holB 2.7.7.7 L DNA polymerase III
HCONIBLK_00267 8.6e-141 S Phosphatidylethanolamine-binding protein
HCONIBLK_00268 0.0 pepD E Peptidase family C69
HCONIBLK_00269 0.0 pepD E Peptidase family C69
HCONIBLK_00270 1.9e-222 S Domain of unknown function (DUF4143)
HCONIBLK_00271 4.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
HCONIBLK_00272 6e-63 S Macrophage migration inhibitory factor (MIF)
HCONIBLK_00273 2.2e-198 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HCONIBLK_00274 7.6e-100 S GtrA-like protein
HCONIBLK_00275 7.1e-175
HCONIBLK_00276 2.6e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
HCONIBLK_00277 6.8e-262 EGP Major facilitator Superfamily
HCONIBLK_00278 1.4e-294 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HCONIBLK_00281 3.7e-251 S Calcineurin-like phosphoesterase
HCONIBLK_00282 5.6e-144 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
HCONIBLK_00283 4.5e-266
HCONIBLK_00284 2.3e-127 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HCONIBLK_00285 1.4e-41 QU41_18010 2.4.2.18 K Lrp/AsnC ligand binding domain
HCONIBLK_00286 1.6e-257 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
HCONIBLK_00287 1.1e-250 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HCONIBLK_00288 1.2e-159 plsC2 2.3.1.51 I Phosphate acyltransferases
HCONIBLK_00289 1.4e-160 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
HCONIBLK_00290 2.8e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HCONIBLK_00292 5.5e-113 S Domain of unknown function (DUF4854)
HCONIBLK_00293 7.4e-179 S CAAX protease self-immunity
HCONIBLK_00294 4.4e-144 M Mechanosensitive ion channel
HCONIBLK_00295 1.9e-115 K Bacterial regulatory proteins, tetR family
HCONIBLK_00296 3.9e-234 MA20_36090 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00297 3.4e-163 S Putative ABC-transporter type IV
HCONIBLK_00298 2.9e-229 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
HCONIBLK_00299 0.0 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00300 5.6e-308 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00301 1.8e-198 yegV G pfkB family carbohydrate kinase
HCONIBLK_00302 2.9e-30 rpmB J Ribosomal L28 family
HCONIBLK_00303 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
HCONIBLK_00304 0.0 M Spy0128-like isopeptide containing domain
HCONIBLK_00305 8.4e-102 rsmD 2.1.1.171 L Conserved hypothetical protein 95
HCONIBLK_00306 4.8e-159 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HCONIBLK_00307 2.7e-120 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HCONIBLK_00308 1.5e-46 CP_0960 S Belongs to the UPF0109 family
HCONIBLK_00309 7.9e-66 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HCONIBLK_00310 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HCONIBLK_00311 9.6e-222 S Endonuclease/Exonuclease/phosphatase family
HCONIBLK_00312 1.5e-161 P Cation efflux family
HCONIBLK_00313 1.5e-265 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HCONIBLK_00314 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCONIBLK_00315 0.0 yjjK S ABC transporter
HCONIBLK_00316 3e-136 guaA1 6.3.5.2 F Peptidase C26
HCONIBLK_00317 3.4e-92 ilvN 2.2.1.6 E ACT domain
HCONIBLK_00318 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
HCONIBLK_00319 9.5e-141 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HCONIBLK_00320 1.4e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HCONIBLK_00321 1.9e-112 yceD S Uncharacterized ACR, COG1399
HCONIBLK_00322 5.8e-121
HCONIBLK_00323 1.3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HCONIBLK_00324 1.4e-49 S Protein of unknown function (DUF3039)
HCONIBLK_00325 6e-196 yghZ C Aldo/keto reductase family
HCONIBLK_00326 8.5e-251 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HCONIBLK_00327 2.4e-46
HCONIBLK_00328 1.5e-135 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HCONIBLK_00329 8.2e-131 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HCONIBLK_00330 1e-245 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
HCONIBLK_00331 4e-184 S Auxin Efflux Carrier
HCONIBLK_00334 1.8e-218 manC 2.7.7.13, 5.3.1.8 M Mannose-6-phosphate isomerase
HCONIBLK_00335 0.0 pgi 5.3.1.9 G Belongs to the GPI family
HCONIBLK_00336 1e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HCONIBLK_00337 2.7e-137 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HCONIBLK_00338 2.4e-144 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCONIBLK_00339 9.7e-159 V ATPases associated with a variety of cellular activities
HCONIBLK_00340 2.8e-255 V Efflux ABC transporter, permease protein
HCONIBLK_00341 1.9e-172 dapE 3.5.1.18 E Peptidase dimerisation domain
HCONIBLK_00342 1.1e-236 dapE 3.5.1.18 E Peptidase dimerisation domain
HCONIBLK_00343 0.0 rne 3.1.26.12 J Ribonuclease E/G family
HCONIBLK_00344 5.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
HCONIBLK_00345 1.5e-39 rpmA J Ribosomal L27 protein
HCONIBLK_00346 4.3e-303
HCONIBLK_00347 7.9e-205 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HCONIBLK_00348 3.7e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
HCONIBLK_00350 8.7e-34 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HCONIBLK_00351 8.4e-134 nusG K Participates in transcription elongation, termination and antitermination
HCONIBLK_00352 1.5e-71 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HCONIBLK_00353 6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HCONIBLK_00354 8.4e-145 QT PucR C-terminal helix-turn-helix domain
HCONIBLK_00355 5.6e-169 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
HCONIBLK_00356 2.6e-104 bioY S BioY family
HCONIBLK_00357 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
HCONIBLK_00358 3.1e-303 pccB I Carboxyl transferase domain
HCONIBLK_00359 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
HCONIBLK_00360 5.9e-79 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HCONIBLK_00362 2.6e-121
HCONIBLK_00363 3.8e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
HCONIBLK_00364 2e-49 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HCONIBLK_00365 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HCONIBLK_00366 2.3e-99 lemA S LemA family
HCONIBLK_00367 0.0 S Predicted membrane protein (DUF2207)
HCONIBLK_00368 4.1e-186 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCONIBLK_00369 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HCONIBLK_00370 9.6e-79 nrdI F Probably involved in ribonucleotide reductase function
HCONIBLK_00371 2e-42 nrdI F Probably involved in ribonucleotide reductase function
HCONIBLK_00372 1.6e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
HCONIBLK_00373 1.8e-300 yegQ O Peptidase family U32 C-terminal domain
HCONIBLK_00374 1e-226 yfiH Q Multi-copper polyphenol oxidoreductase laccase
HCONIBLK_00375 2.6e-149 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HCONIBLK_00376 1e-133 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HCONIBLK_00377 8.1e-84 D nuclear chromosome segregation
HCONIBLK_00378 2.4e-269 pepC 3.4.22.40 E Peptidase C1-like family
HCONIBLK_00379 2.1e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HCONIBLK_00380 0.0 I Psort location CytoplasmicMembrane, score 9.99
HCONIBLK_00381 2.2e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HCONIBLK_00382 7.4e-121 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HCONIBLK_00383 1.6e-219 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HCONIBLK_00384 3.3e-132 KT Transcriptional regulatory protein, C terminal
HCONIBLK_00385 3.2e-206 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
HCONIBLK_00386 8.5e-171 pstC P probably responsible for the translocation of the substrate across the membrane
HCONIBLK_00387 8.3e-174 pstA P Phosphate transport system permease
HCONIBLK_00388 8.9e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HCONIBLK_00389 1.3e-249 pbuO S Permease family
HCONIBLK_00390 9.3e-164 P Zinc-uptake complex component A periplasmic
HCONIBLK_00391 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HCONIBLK_00392 2.4e-44 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HCONIBLK_00393 9.2e-263 T Forkhead associated domain
HCONIBLK_00394 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
HCONIBLK_00395 5.6e-39
HCONIBLK_00396 7.9e-103 flgA NO SAF
HCONIBLK_00397 6.8e-32 fmdB S Putative regulatory protein
HCONIBLK_00398 4e-141 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HCONIBLK_00399 3.3e-121 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
HCONIBLK_00400 2.5e-196
HCONIBLK_00401 2.3e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HCONIBLK_00405 1.9e-25 rpmG J Ribosomal protein L33
HCONIBLK_00406 1.4e-226 murB 1.3.1.98 M Cell wall formation
HCONIBLK_00407 6.6e-290 E aromatic amino acid transport protein AroP K03293
HCONIBLK_00408 7.6e-60 fdxA C 4Fe-4S binding domain
HCONIBLK_00409 6.8e-220 dapC E Aminotransferase class I and II
HCONIBLK_00410 2e-252 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HCONIBLK_00412 1.3e-190 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HCONIBLK_00413 2.8e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
HCONIBLK_00414 3.9e-122
HCONIBLK_00415 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HCONIBLK_00416 1.2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HCONIBLK_00417 8.5e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
HCONIBLK_00418 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCONIBLK_00419 6.7e-209 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
HCONIBLK_00420 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HCONIBLK_00421 1.6e-190 K Psort location Cytoplasmic, score
HCONIBLK_00422 1.1e-152 ywiC S YwiC-like protein
HCONIBLK_00423 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
HCONIBLK_00424 3.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HCONIBLK_00425 6.8e-116 rplD J Forms part of the polypeptide exit tunnel
HCONIBLK_00426 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HCONIBLK_00427 1.2e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HCONIBLK_00428 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HCONIBLK_00429 6.7e-57 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HCONIBLK_00430 3.9e-124 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HCONIBLK_00431 2e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HCONIBLK_00432 7e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
HCONIBLK_00433 8.3e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HCONIBLK_00434 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HCONIBLK_00435 3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HCONIBLK_00436 1.7e-105 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HCONIBLK_00437 3.1e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HCONIBLK_00438 1.9e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HCONIBLK_00439 2.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HCONIBLK_00440 1.3e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HCONIBLK_00441 8.2e-94 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HCONIBLK_00442 2.5e-23 rpmD J Ribosomal protein L30p/L7e
HCONIBLK_00443 7.4e-77 rplO J binds to the 23S rRNA
HCONIBLK_00444 1.5e-250 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HCONIBLK_00445 3.2e-101 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HCONIBLK_00446 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HCONIBLK_00447 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HCONIBLK_00448 2.1e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HCONIBLK_00449 5.7e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HCONIBLK_00450 5.2e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCONIBLK_00451 1e-70 rplQ J Ribosomal protein L17
HCONIBLK_00452 2.1e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HCONIBLK_00454 5.1e-162
HCONIBLK_00455 3.2e-195 nusA K Participates in both transcription termination and antitermination
HCONIBLK_00456 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HCONIBLK_00457 6.4e-74 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HCONIBLK_00458 5.9e-194 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HCONIBLK_00459 7.8e-233 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
HCONIBLK_00460 1.5e-275 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HCONIBLK_00461 1.9e-92
HCONIBLK_00463 1.8e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HCONIBLK_00464 3.5e-180 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HCONIBLK_00466 1.9e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HCONIBLK_00467 4.4e-219 I Diacylglycerol kinase catalytic domain
HCONIBLK_00468 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
HCONIBLK_00469 2.2e-290 S alpha beta
HCONIBLK_00470 9.6e-112 S Protein of unknown function (DUF4125)
HCONIBLK_00471 0.0 S Domain of unknown function (DUF4037)
HCONIBLK_00472 6e-126 degU K helix_turn_helix, Lux Regulon
HCONIBLK_00473 2e-269 tcsS3 KT PspC domain
HCONIBLK_00474 0.0 pspC KT PspC domain
HCONIBLK_00475 7.2e-102
HCONIBLK_00476 9.5e-225 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HCONIBLK_00477 2.4e-130 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HCONIBLK_00478 1.6e-28 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
HCONIBLK_00480 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HCONIBLK_00481 2.2e-103
HCONIBLK_00482 1.4e-291 E Phospholipase B
HCONIBLK_00483 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
HCONIBLK_00484 0.0 gadC E Amino acid permease
HCONIBLK_00485 9.2e-302 E Serine carboxypeptidase
HCONIBLK_00486 1.7e-274 puuP_1 E Amino acid permease
HCONIBLK_00487 9.9e-77 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HCONIBLK_00488 3.4e-140 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HCONIBLK_00489 0.0 4.2.1.53 S MCRA family
HCONIBLK_00490 5.6e-64 3.5.1.10 C Zinc-binding dehydrogenase
HCONIBLK_00491 1.2e-123 1.6.5.5 C Zinc-binding dehydrogenase
HCONIBLK_00492 6e-282 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G Phosphomannose isomerase type I
HCONIBLK_00493 6.7e-22
HCONIBLK_00494 5.5e-224 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCONIBLK_00495 3.3e-121 phoU P Plays a role in the regulation of phosphate uptake
HCONIBLK_00496 1.6e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HCONIBLK_00497 5.6e-173 usp 3.5.1.28 CBM50 S CHAP domain
HCONIBLK_00498 2.1e-98 M NlpC/P60 family
HCONIBLK_00499 2.4e-195 T Universal stress protein family
HCONIBLK_00500 5.9e-73 attW O OsmC-like protein
HCONIBLK_00501 1.1e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HCONIBLK_00502 4.1e-132 folA 1.5.1.3 H dihydrofolate reductase
HCONIBLK_00503 5.6e-100 ptpA 3.1.3.48 T low molecular weight
HCONIBLK_00504 3.6e-201 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HCONIBLK_00505 1.1e-161 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HCONIBLK_00507 2.8e-183 XK27_05540 S DUF218 domain
HCONIBLK_00508 7.7e-188 3.1.3.5 S 5'-nucleotidase
HCONIBLK_00509 4.6e-108
HCONIBLK_00510 2.8e-293 L AAA ATPase domain
HCONIBLK_00511 1.1e-54 S Cutinase
HCONIBLK_00512 1.4e-228 S Uncharacterized protein conserved in bacteria (DUF2130)
HCONIBLK_00513 3.3e-294 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00514 3e-145 S Domain of unknown function (DUF4194)
HCONIBLK_00515 0.0 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00516 1.4e-236 S Psort location Cytoplasmic, score 8.87
HCONIBLK_00518 2.6e-64 yeaO K Protein of unknown function, DUF488
HCONIBLK_00519 2.8e-274 lacS G Psort location CytoplasmicMembrane, score 10.00
HCONIBLK_00520 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HCONIBLK_00521 2.8e-185 lacR K Transcriptional regulator, LacI family
HCONIBLK_00522 5.7e-117 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCONIBLK_00523 5.8e-62
HCONIBLK_00524 7e-96 S Domain of unknown function (DUF4190)
HCONIBLK_00525 1.3e-77 S Domain of unknown function (DUF4190)
HCONIBLK_00526 9.4e-205 G Bacterial extracellular solute-binding protein
HCONIBLK_00527 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
HCONIBLK_00528 6.3e-174 G ABC transporter permease
HCONIBLK_00529 1.8e-173 G Binding-protein-dependent transport system inner membrane component
HCONIBLK_00530 1.7e-187 K Periplasmic binding protein domain
HCONIBLK_00534 1.3e-182 3.4.14.13 M Glycosyltransferase like family 2
HCONIBLK_00535 1.2e-294 S AI-2E family transporter
HCONIBLK_00536 2.9e-243 epsG M Glycosyl transferase family 21
HCONIBLK_00537 1.3e-162 natA V ATPases associated with a variety of cellular activities
HCONIBLK_00538 0.0
HCONIBLK_00539 5.3e-237 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
HCONIBLK_00540 5.9e-216 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HCONIBLK_00541 2.5e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HCONIBLK_00542 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HCONIBLK_00543 3e-143 folK 2.5.1.15, 2.6.1.85, 2.7.6.3, 3.5.4.16, 4.1.2.25 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HCONIBLK_00544 2.3e-113 S Protein of unknown function (DUF3180)
HCONIBLK_00545 2.6e-174 tesB I Thioesterase-like superfamily
HCONIBLK_00546 7.3e-300 yjjK S ATP-binding cassette protein, ChvD family
HCONIBLK_00547 3.2e-66 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HCONIBLK_00548 1e-256 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
HCONIBLK_00549 1.3e-111 ykoE S ABC-type cobalt transport system, permease component
HCONIBLK_00550 2.2e-133
HCONIBLK_00552 1.3e-173
HCONIBLK_00553 1.4e-35 rpmE J Binds the 23S rRNA
HCONIBLK_00554 4e-272 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HCONIBLK_00555 0.0 G Belongs to the glycosyl hydrolase 43 family
HCONIBLK_00556 4.9e-190 K Bacterial regulatory proteins, lacI family
HCONIBLK_00557 8.8e-245 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
HCONIBLK_00558 2.9e-193 MA20_14025 U Binding-protein-dependent transport system inner membrane component
HCONIBLK_00559 3.3e-158 MA20_14020 P Binding-protein-dependent transport system inner membrane component
HCONIBLK_00560 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HCONIBLK_00561 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
HCONIBLK_00562 2.3e-236 CE10 I Belongs to the type-B carboxylesterase lipase family
HCONIBLK_00563 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
HCONIBLK_00564 1.7e-290 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
HCONIBLK_00565 3.6e-219 xylR GK ROK family
HCONIBLK_00566 8.6e-36 rpmE J Binds the 23S rRNA
HCONIBLK_00567 4.9e-167 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HCONIBLK_00568 3.7e-176 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HCONIBLK_00569 2.6e-115 ywlC 2.7.7.87 J Belongs to the SUA5 family
HCONIBLK_00570 1.3e-197 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
HCONIBLK_00571 2.2e-290 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HCONIBLK_00572 5.7e-123 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
HCONIBLK_00573 2.7e-157 supH S Sucrose-6F-phosphate phosphohydrolase
HCONIBLK_00574 1.6e-277 recD2 3.6.4.12 L PIF1-like helicase
HCONIBLK_00575 2.5e-74
HCONIBLK_00576 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HCONIBLK_00577 1.2e-134 L Single-strand binding protein family
HCONIBLK_00578 0.0 pepO 3.4.24.71 O Peptidase family M13
HCONIBLK_00579 5.7e-104 S Short repeat of unknown function (DUF308)
HCONIBLK_00580 2e-130 map 3.4.11.18 E Methionine aminopeptidase
HCONIBLK_00581 2.2e-251 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
HCONIBLK_00582 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HCONIBLK_00583 2.1e-169 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
HCONIBLK_00584 5.1e-204 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HCONIBLK_00585 3.9e-227 ftsE D Cell division ATP-binding protein FtsE
HCONIBLK_00586 9.4e-164 ftsX D Part of the ABC transporter FtsEX involved in cellular division
HCONIBLK_00587 3.3e-184 usp 3.5.1.28 CBM50 D CHAP domain protein
HCONIBLK_00588 4.2e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HCONIBLK_00589 2.3e-154 pknD ET ABC transporter, substrate-binding protein, family 3
HCONIBLK_00590 1.9e-167 pknD ET ABC transporter, substrate-binding protein, family 3
HCONIBLK_00591 4.4e-151 yecS E Binding-protein-dependent transport system inner membrane component
HCONIBLK_00592 1.1e-153 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
HCONIBLK_00593 1e-181 K Psort location Cytoplasmic, score
HCONIBLK_00594 1.4e-127 K helix_turn_helix, Lux Regulon
HCONIBLK_00595 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HCONIBLK_00596 5.2e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
HCONIBLK_00597 3.2e-68
HCONIBLK_00598 1.1e-136 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HCONIBLK_00599 0.0 E ABC transporter, substrate-binding protein, family 5
HCONIBLK_00600 7.8e-169 P Binding-protein-dependent transport system inner membrane component
HCONIBLK_00601 1.5e-155 EP Binding-protein-dependent transport system inner membrane component
HCONIBLK_00602 1.7e-140 P ATPases associated with a variety of cellular activities
HCONIBLK_00603 3.6e-140 sapF E ATPases associated with a variety of cellular activities
HCONIBLK_00604 1.4e-220 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
HCONIBLK_00605 1e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
HCONIBLK_00606 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HCONIBLK_00607 2.2e-173 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HCONIBLK_00608 6.4e-107 J Acetyltransferase (GNAT) domain
HCONIBLK_00611 1.2e-38 M1-431 S Protein of unknown function (DUF1706)
HCONIBLK_00612 8.1e-22 M1-431 S Protein of unknown function (DUF1706)
HCONIBLK_00614 1.2e-58
HCONIBLK_00615 2.1e-64
HCONIBLK_00616 2.6e-73 nudG 3.6.1.55, 3.6.1.65 L NUDIX domain
HCONIBLK_00617 0.0 KL Domain of unknown function (DUF3427)
HCONIBLK_00618 3.6e-63 mloA S Fic/DOC family
HCONIBLK_00619 0.0 S Protein of unknown function (DUF1524)
HCONIBLK_00620 4.4e-94 gepA S Protein of unknown function (DUF4065)
HCONIBLK_00621 3.1e-92 doc S Fic/DOC family
HCONIBLK_00622 1.2e-88 XK27_03610 K Acetyltransferase (GNAT) domain
HCONIBLK_00623 3e-142 S 3-oxo-5-alpha-steroid 4-dehydrogenase
HCONIBLK_00624 7e-228 gldA 1.1.1.1, 1.1.1.6 C Iron-containing alcohol dehydrogenase
HCONIBLK_00625 6.6e-95 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HCONIBLK_00626 5.8e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HCONIBLK_00627 1.1e-261 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HCONIBLK_00628 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HCONIBLK_00629 3.7e-221 ybiR P Citrate transporter
HCONIBLK_00631 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HCONIBLK_00632 2.8e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HCONIBLK_00633 6.3e-226 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HCONIBLK_00634 4.8e-72 zur P Belongs to the Fur family
HCONIBLK_00635 0.0 lysX S Uncharacterised conserved protein (DUF2156)
HCONIBLK_00636 1.7e-265 S Putative esterase
HCONIBLK_00637 2.2e-240 purD 6.3.4.13 F Belongs to the GARS family
HCONIBLK_00638 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HCONIBLK_00639 3e-303 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HCONIBLK_00640 5.7e-280 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
HCONIBLK_00641 1.7e-72
HCONIBLK_00642 7.3e-215 S 50S ribosome-binding GTPase
HCONIBLK_00643 6.9e-101
HCONIBLK_00644 2.7e-89 S Pyridoxamine 5'-phosphate oxidase
HCONIBLK_00645 1.4e-107 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
HCONIBLK_00647 1e-226
HCONIBLK_00648 2.8e-126
HCONIBLK_00649 2.1e-68
HCONIBLK_00650 1.8e-107
HCONIBLK_00651 9.9e-209 S Short C-terminal domain
HCONIBLK_00652 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
HCONIBLK_00653 8.6e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HCONIBLK_00654 8.9e-234 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HCONIBLK_00655 1.7e-234 M Glycosyl transferase 4-like domain
HCONIBLK_00656 9.4e-197 ltaE 4.1.2.48 E Beta-eliminating lyase
HCONIBLK_00658 2.7e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HCONIBLK_00659 2.5e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HCONIBLK_00660 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HCONIBLK_00661 1.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HCONIBLK_00662 7.7e-123 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HCONIBLK_00663 2.6e-95
HCONIBLK_00664 5.1e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HCONIBLK_00665 9.5e-80 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HCONIBLK_00666 2.8e-240 carA 6.3.5.5 F Belongs to the CarA family
HCONIBLK_00667 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
HCONIBLK_00668 8.9e-181 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HCONIBLK_00669 1.2e-114 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HCONIBLK_00670 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
HCONIBLK_00671 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HCONIBLK_00672 3.1e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HCONIBLK_00673 2.5e-255 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
HCONIBLK_00674 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HCONIBLK_00675 1.7e-184 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HCONIBLK_00676 3.5e-86 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
HCONIBLK_00677 6.3e-128 apl 3.1.3.1 S SNARE associated Golgi protein
HCONIBLK_00678 1.2e-291 arc O AAA ATPase forming ring-shaped complexes
HCONIBLK_00679 3.3e-310 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
HCONIBLK_00680 2.4e-172 hisN 3.1.3.25 G Inositol monophosphatase family
HCONIBLK_00681 2.5e-30 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
HCONIBLK_00682 5e-292 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
HCONIBLK_00683 6.2e-42 hup L Belongs to the bacterial histone-like protein family
HCONIBLK_00684 0.0 S Lysylphosphatidylglycerol synthase TM region
HCONIBLK_00685 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
HCONIBLK_00686 2.1e-293 S PGAP1-like protein
HCONIBLK_00688 3.6e-87
HCONIBLK_00689 9.3e-181 S von Willebrand factor (vWF) type A domain
HCONIBLK_00690 6.3e-196 S von Willebrand factor (vWF) type A domain
HCONIBLK_00691 4.5e-83
HCONIBLK_00692 9.8e-180 S Protein of unknown function DUF58
HCONIBLK_00693 4.2e-192 moxR S ATPase family associated with various cellular activities (AAA)
HCONIBLK_00694 1.5e-140 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HCONIBLK_00695 3.7e-80 S LytR cell envelope-related transcriptional attenuator
HCONIBLK_00696 1.8e-33 cspA K 'Cold-shock' DNA-binding domain
HCONIBLK_00697 3.5e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HCONIBLK_00698 6.5e-42 S Proteins of 100 residues with WXG
HCONIBLK_00699 5e-134
HCONIBLK_00700 1.3e-134 KT Response regulator receiver domain protein
HCONIBLK_00701 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCONIBLK_00702 1.2e-79 cspB K 'Cold-shock' DNA-binding domain
HCONIBLK_00703 8.2e-210 S Protein of unknown function (DUF3027)
HCONIBLK_00704 7.3e-117
HCONIBLK_00705 5.6e-183 uspA T Belongs to the universal stress protein A family
HCONIBLK_00706 0.0 clpC O ATPase family associated with various cellular activities (AAA)
HCONIBLK_00707 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HCONIBLK_00708 8.7e-259 hisS 6.1.1.21 J Histidyl-tRNA synthetase
HCONIBLK_00709 3.7e-228 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
HCONIBLK_00710 9.6e-149 aroD S Serine aminopeptidase, S33
HCONIBLK_00711 3e-142 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
HCONIBLK_00712 4.3e-155 gluB ET Belongs to the bacterial solute-binding protein 3 family
HCONIBLK_00713 5.2e-111 gluC E Binding-protein-dependent transport system inner membrane component
HCONIBLK_00714 2.1e-202 gluD E Binding-protein-dependent transport system inner membrane component
HCONIBLK_00715 9.8e-188 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
HCONIBLK_00716 0.0 L DEAD DEAH box helicase
HCONIBLK_00717 7.2e-262 rarA L Recombination factor protein RarA
HCONIBLK_00718 5.7e-267 EGP Major facilitator Superfamily
HCONIBLK_00719 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HCONIBLK_00720 2.5e-200 L Transposase, Mutator family
HCONIBLK_00722 1.4e-308
HCONIBLK_00723 1.3e-142 E Psort location Cytoplasmic, score 8.87
HCONIBLK_00724 2.4e-65 S Zincin-like metallopeptidase
HCONIBLK_00725 4.9e-72 yccF S Inner membrane component domain
HCONIBLK_00726 1.1e-141 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HCONIBLK_00727 2.7e-46 yhbY J CRS1_YhbY
HCONIBLK_00728 8.6e-164 yvgN 1.1.1.346 S Aldo/keto reductase family
HCONIBLK_00729 0.0 ecfA GP ABC transporter, ATP-binding protein
HCONIBLK_00730 9.9e-98 ecfA GP ABC transporter, ATP-binding protein
HCONIBLK_00731 1.3e-134 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
HCONIBLK_00732 1.7e-223 E Aminotransferase class I and II
HCONIBLK_00733 4e-150 bioM P ATPases associated with a variety of cellular activities
HCONIBLK_00734 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCONIBLK_00735 0.0 S Tetratricopeptide repeat
HCONIBLK_00736 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HCONIBLK_00737 3.2e-206 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HCONIBLK_00738 2.6e-109 ykoE S ABC-type cobalt transport system, permease component
HCONIBLK_00739 7e-283 glnA 6.3.1.2 E glutamine synthetase
HCONIBLK_00740 1.6e-148 S Domain of unknown function (DUF4191)
HCONIBLK_00741 3.4e-280 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HCONIBLK_00742 9.5e-104 S Protein of unknown function (DUF3043)
HCONIBLK_00743 9.7e-266 argE E Peptidase dimerisation domain
HCONIBLK_00744 1.3e-212 2.7.13.3 T Histidine kinase
HCONIBLK_00745 2.1e-44
HCONIBLK_00746 8.2e-162 V N-Acetylmuramoyl-L-alanine amidase
HCONIBLK_00747 1.3e-226 ytrE V lipoprotein transporter activity
HCONIBLK_00748 3.2e-107 ykoE S ABC-type cobalt transport system, permease component
HCONIBLK_00749 0.0 cbiQ P ATPases associated with a variety of cellular activities
HCONIBLK_00750 4.8e-131 V ABC transporter, ATP-binding protein
HCONIBLK_00751 3.4e-218 V FtsX-like permease family
HCONIBLK_00752 7.1e-16 V FtsX-like permease family
HCONIBLK_00753 8.7e-170 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HCONIBLK_00754 2.3e-177 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HCONIBLK_00755 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
HCONIBLK_00756 1.8e-147
HCONIBLK_00757 6.5e-204 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HCONIBLK_00758 5.1e-207 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HCONIBLK_00759 3.3e-180 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HCONIBLK_00760 3.4e-241 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
HCONIBLK_00761 2.9e-184 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HCONIBLK_00762 1.4e-90 argR K Regulates arginine biosynthesis genes
HCONIBLK_00763 3.2e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HCONIBLK_00764 3e-284 argH 4.3.2.1 E argininosuccinate lyase
HCONIBLK_00765 9.5e-155 IQ Enoyl-(Acyl carrier protein) reductase
HCONIBLK_00766 6.2e-90 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HCONIBLK_00767 1.4e-256 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HCONIBLK_00768 2.2e-158 L Tetratricopeptide repeat
HCONIBLK_00769 1.5e-194 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HCONIBLK_00770 5.4e-144 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HCONIBLK_00771 3.9e-273 trkB P Cation transport protein
HCONIBLK_00772 2.7e-117 trkA P TrkA-N domain
HCONIBLK_00773 5.6e-183 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HCONIBLK_00774 0.0 recN L May be involved in recombinational repair of damaged DNA
HCONIBLK_00775 3.3e-129 S Haloacid dehalogenase-like hydrolase
HCONIBLK_00776 1.5e-288 thrC 4.2.3.1 E Threonine synthase N terminus
HCONIBLK_00777 3.5e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HCONIBLK_00778 1.9e-115
HCONIBLK_00779 7.8e-134 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HCONIBLK_00780 8.2e-193 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCONIBLK_00782 1e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HCONIBLK_00783 4.2e-71 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HCONIBLK_00784 8e-122 gpmB 3.1.3.73, 3.1.3.85 G Phosphoglycerate mutase family
HCONIBLK_00785 1.8e-82
HCONIBLK_00788 8.3e-72 pdxH S Pfam:Pyridox_oxidase
HCONIBLK_00789 3e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HCONIBLK_00790 1.2e-169 corA P CorA-like Mg2+ transporter protein
HCONIBLK_00791 6.1e-168 ET Bacterial periplasmic substrate-binding proteins
HCONIBLK_00792 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCONIBLK_00793 8.6e-118 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
HCONIBLK_00794 0.0 comE S Competence protein
HCONIBLK_00795 1.8e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
HCONIBLK_00796 8e-114 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
HCONIBLK_00797 9.2e-158 yeaZ 2.3.1.234 O Glycoprotease family
HCONIBLK_00798 7.5e-91 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
HCONIBLK_00799 3.6e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HCONIBLK_00801 1.9e-89
HCONIBLK_00803 3.6e-61
HCONIBLK_00804 4.9e-103 M Peptidase family M23
HCONIBLK_00805 2.5e-278 G ABC transporter substrate-binding protein
HCONIBLK_00806 9.7e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
HCONIBLK_00807 6.2e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
HCONIBLK_00808 1.4e-19
HCONIBLK_00809 1.5e-297 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
HCONIBLK_00810 8.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCONIBLK_00811 1.9e-161 rpsB J Belongs to the universal ribosomal protein uS2 family
HCONIBLK_00812 7.5e-139 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HCONIBLK_00813 1.3e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HCONIBLK_00814 1.2e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HCONIBLK_00815 5.5e-175 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
HCONIBLK_00816 1.2e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HCONIBLK_00817 1.4e-104 K WHG domain
HCONIBLK_00818 8.4e-114 nodI V ATPases associated with a variety of cellular activities
HCONIBLK_00819 2.2e-134 S ABC-2 type transporter
HCONIBLK_00820 3.9e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HCONIBLK_00821 3.3e-76 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HCONIBLK_00822 1.5e-299 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HCONIBLK_00823 8.8e-115 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
HCONIBLK_00826 0.0 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HCONIBLK_00827 6.4e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HCONIBLK_00828 7.1e-183 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HCONIBLK_00829 4.5e-123 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
HCONIBLK_00830 2.2e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
HCONIBLK_00831 1.2e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
HCONIBLK_00832 1.2e-109 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCONIBLK_00833 8.7e-176 S Bacterial protein of unknown function (DUF881)
HCONIBLK_00834 4.8e-33 sbp S Protein of unknown function (DUF1290)
HCONIBLK_00835 3.2e-153 S Bacterial protein of unknown function (DUF881)
HCONIBLK_00836 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
HCONIBLK_00837 3.1e-133 K helix_turn_helix, mercury resistance
HCONIBLK_00838 5e-69
HCONIBLK_00839 1.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCONIBLK_00840 8.3e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HCONIBLK_00841 7.4e-140 pgp 3.1.3.18 S HAD-hyrolase-like
HCONIBLK_00842 3.9e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
HCONIBLK_00843 0.0 helY L DEAD DEAH box helicase
HCONIBLK_00844 5.8e-36
HCONIBLK_00845 0.0 pafB K WYL domain
HCONIBLK_00846 9.1e-283 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
HCONIBLK_00848 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
HCONIBLK_00849 1.7e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HCONIBLK_00850 2e-167 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HCONIBLK_00851 5.7e-22
HCONIBLK_00852 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HCONIBLK_00853 2.1e-244
HCONIBLK_00854 3.4e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HCONIBLK_00855 1.5e-222 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HCONIBLK_00856 1.7e-102 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HCONIBLK_00857 1.4e-53 yajC U Preprotein translocase subunit
HCONIBLK_00858 5e-204 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HCONIBLK_00859 1.7e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HCONIBLK_00860 2.5e-101 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HCONIBLK_00861 3.6e-129 yebC K transcriptional regulatory protein
HCONIBLK_00862 8.2e-190 pimA 2.4.1.345 GT4 M Glycosyl transferases group 1
HCONIBLK_00863 1.9e-194 htrB 2.3.1.241, 2.3.1.265 M Bacterial lipid A biosynthesis acyltransferase
HCONIBLK_00864 1.1e-116 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
HCONIBLK_00865 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HCONIBLK_00866 1.7e-98 S ATPases associated with a variety of cellular activities
HCONIBLK_00868 1.4e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HCONIBLK_00869 1.4e-23
HCONIBLK_00875 2.3e-158 S PAC2 family
HCONIBLK_00876 2.6e-150 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HCONIBLK_00877 4.2e-160 G Fructosamine kinase
HCONIBLK_00878 2.8e-218 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HCONIBLK_00879 3e-201 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HCONIBLK_00880 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
HCONIBLK_00881 1.4e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HCONIBLK_00882 1.3e-66 S PFAM Pentapeptide repeats (8 copies)
HCONIBLK_00883 4e-231 yugH 2.6.1.1 E Aminotransferase class I and II
HCONIBLK_00884 4.6e-91 alaR K helix_turn_helix ASNC type
HCONIBLK_00885 8.7e-309 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
HCONIBLK_00886 1.1e-160 S Sucrose-6F-phosphate phosphohydrolase
HCONIBLK_00887 4.7e-25 secG U Preprotein translocase SecG subunit
HCONIBLK_00888 9.5e-152 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HCONIBLK_00889 3.1e-223 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
HCONIBLK_00890 4.3e-175 whiA K May be required for sporulation
HCONIBLK_00891 6e-174 rapZ S Displays ATPase and GTPase activities
HCONIBLK_00892 9.8e-177 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
HCONIBLK_00893 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HCONIBLK_00894 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCONIBLK_00895 7e-32 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HCONIBLK_00896 9.8e-180 wcoO
HCONIBLK_00897 2.1e-99 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
HCONIBLK_00898 2.7e-122 S Phospholipase/Carboxylesterase
HCONIBLK_00899 4.1e-300 ybiT S ABC transporter
HCONIBLK_00900 1.9e-195 cat P Cation efflux family
HCONIBLK_00901 2.2e-145 4.1.1.44 S Carboxymuconolactone decarboxylase family
HCONIBLK_00902 6.4e-184 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HCONIBLK_00903 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HCONIBLK_00904 2e-108 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
HCONIBLK_00905 0.0 trxB1 1.8.1.9 C Thioredoxin domain
HCONIBLK_00906 5e-173 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
HCONIBLK_00907 1.1e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HCONIBLK_00908 1.8e-189 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
HCONIBLK_00909 1.2e-182 draG O ADP-ribosylglycohydrolase
HCONIBLK_00910 2.6e-58 ytfH K HxlR-like helix-turn-helix
HCONIBLK_00911 2.8e-51 3.6.1.55 L NUDIX domain
HCONIBLK_00912 8.9e-80 2.3.1.1 K Psort location Cytoplasmic, score 8.87
HCONIBLK_00913 1.9e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCONIBLK_00914 7.7e-188 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HCONIBLK_00915 3.5e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
HCONIBLK_00916 4.5e-177 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
HCONIBLK_00917 9.1e-283 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HCONIBLK_00918 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
HCONIBLK_00919 4.6e-188 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HCONIBLK_00920 3.1e-89 yneG S Domain of unknown function (DUF4186)
HCONIBLK_00921 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
HCONIBLK_00922 1.5e-160 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
HCONIBLK_00923 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HCONIBLK_00924 1.5e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
HCONIBLK_00925 2.7e-199 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
HCONIBLK_00926 3.4e-160 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
HCONIBLK_00927 7.8e-246 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
HCONIBLK_00928 2.6e-88 bcp 1.11.1.15 O Redoxin
HCONIBLK_00929 4.2e-80
HCONIBLK_00930 1.7e-306 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
HCONIBLK_00931 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
HCONIBLK_00932 2.8e-262 hemN H Involved in the biosynthesis of porphyrin-containing compound
HCONIBLK_00933 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HCONIBLK_00934 3.4e-34 rpsT J Binds directly to 16S ribosomal RNA
HCONIBLK_00935 5.2e-139 S UPF0126 domain
HCONIBLK_00936 5.1e-228 ilvE 2.6.1.42 E Amino-transferase class IV
HCONIBLK_00937 5e-108 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HCONIBLK_00938 1.3e-195 S alpha beta
HCONIBLK_00939 1.8e-254 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HCONIBLK_00940 1.2e-46 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
HCONIBLK_00941 9.7e-203 pntAA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
HCONIBLK_00942 0.0 fadD 6.2.1.3 I AMP-binding enzyme
HCONIBLK_00943 3.4e-183 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HCONIBLK_00944 8.4e-249 corC S CBS domain
HCONIBLK_00945 2.5e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HCONIBLK_00946 1.6e-213 phoH T PhoH-like protein
HCONIBLK_00947 2.5e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
HCONIBLK_00948 3.2e-144 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HCONIBLK_00950 2.8e-165 spoU 2.1.1.185 J SpoU rRNA Methylase family
HCONIBLK_00951 3.1e-132 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HCONIBLK_00952 1.6e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HCONIBLK_00953 3.5e-92 yitW S Iron-sulfur cluster assembly protein
HCONIBLK_00954 8.9e-104 iscU C SUF system FeS assembly protein, NifU family
HCONIBLK_00955 3.5e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HCONIBLK_00956 2.3e-142 sufC O FeS assembly ATPase SufC
HCONIBLK_00957 5.5e-228 sufD O FeS assembly protein SufD
HCONIBLK_00958 1.4e-289 sufB O FeS assembly protein SufB
HCONIBLK_00959 0.0 S L,D-transpeptidase catalytic domain
HCONIBLK_00960 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HCONIBLK_00961 1.7e-48 M Aamy_C
HCONIBLK_00962 1e-184 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCONIBLK_00963 2.8e-84 dexB 2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97 GH101,GH13,GH29,GH31 M Aamy_C
HCONIBLK_00964 7e-95 amy 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
HCONIBLK_00967 2e-222
HCONIBLK_00968 8.7e-215
HCONIBLK_00969 1.3e-80
HCONIBLK_00970 9.9e-82
HCONIBLK_00971 7.3e-191
HCONIBLK_00972 1.8e-70 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HCONIBLK_00973 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HCONIBLK_00974 5.4e-220 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HCONIBLK_00975 1.3e-37 3.4.23.43 S Type IV leader peptidase family
HCONIBLK_00976 1.8e-199 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HCONIBLK_00977 1.2e-85 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HCONIBLK_00978 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HCONIBLK_00979 1.4e-34
HCONIBLK_00980 6.3e-64 WQ51_05790 S Bacterial protein of unknown function (DUF948)
HCONIBLK_00981 1.6e-128 pgm3 3.1.3.85 G Phosphoglycerate mutase family
HCONIBLK_00982 8.9e-63 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HCONIBLK_00983 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HCONIBLK_00984 0.0 pcrA 3.6.4.12 L DNA helicase
HCONIBLK_00985 3e-91 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HCONIBLK_00986 4e-265 pbuX F Permease family
HCONIBLK_00987 1.5e-112 M Protein of unknown function (DUF3737)
HCONIBLK_00988 1.8e-27 patB 4.4.1.8 E Aminotransferase, class I II
HCONIBLK_00989 4.7e-179 patB 4.4.1.8 E Aminotransferase, class I II
HCONIBLK_00990 4.2e-186 K TRANSCRIPTIONal
HCONIBLK_00991 0.0 amyA 3.2.1.1 GH13 G Glycosyl hydrolase family 70
HCONIBLK_00992 1e-141 S Peptidase C26
HCONIBLK_00993 2.3e-84 proX S Aminoacyl-tRNA editing domain
HCONIBLK_00994 3.9e-97 S ABC-2 family transporter protein
HCONIBLK_00995 8.7e-167 V ATPases associated with a variety of cellular activities
HCONIBLK_00996 2.4e-66 K helix_turn_helix gluconate operon transcriptional repressor
HCONIBLK_00997 2.2e-190 K Helix-turn-helix XRE-family like proteins
HCONIBLK_00998 7.7e-183
HCONIBLK_00999 2.3e-141
HCONIBLK_01000 1.4e-50 4.2.99.21 E Chorismate mutase type II
HCONIBLK_01001 3.4e-160 E -acetyltransferase
HCONIBLK_01002 3.9e-71 K Acetyltransferase (GNAT) family
HCONIBLK_01003 1e-107 adk 2.7.4.3 F adenylate kinase activity
HCONIBLK_01004 2e-64 S AAA domain
HCONIBLK_01005 0.0 tetP J elongation factor G
HCONIBLK_01006 4.6e-177 insH6 L Transposase domain (DUF772)
HCONIBLK_01007 1.3e-69 K sequence-specific DNA binding
HCONIBLK_01008 3.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HCONIBLK_01009 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
HCONIBLK_01010 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HCONIBLK_01011 5.7e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HCONIBLK_01012 4e-267 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HCONIBLK_01014 2.4e-231 ykiI
HCONIBLK_01015 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCONIBLK_01016 5.7e-123 3.6.1.13 L NUDIX domain
HCONIBLK_01017 8.3e-184 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
HCONIBLK_01018 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HCONIBLK_01020 7.1e-117 pdtaR T Response regulator receiver domain protein
HCONIBLK_01021 2.6e-120 aspA 3.6.1.13 L NUDIX domain
HCONIBLK_01023 1.4e-275 pyk 2.7.1.40 G Pyruvate kinase
HCONIBLK_01024 2.5e-178 terC P Integral membrane protein, TerC family
HCONIBLK_01025 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HCONIBLK_01026 3.8e-119 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HCONIBLK_01027 1.1e-267
HCONIBLK_01028 3.1e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HCONIBLK_01029 7.3e-186 P Zinc-uptake complex component A periplasmic
HCONIBLK_01030 5.1e-170 znuC P ATPases associated with a variety of cellular activities
HCONIBLK_01031 1.7e-143 znuB U ABC 3 transport family
HCONIBLK_01032 1.9e-89 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HCONIBLK_01033 6.6e-102 carD K CarD-like/TRCF domain
HCONIBLK_01034 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HCONIBLK_01035 8.2e-131 T Response regulator receiver domain protein
HCONIBLK_01036 1.2e-202 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCONIBLK_01037 1.3e-145 ctsW S Phosphoribosyl transferase domain
HCONIBLK_01038 7.9e-154 cof 5.2.1.8 T Eukaryotic phosphomannomutase
HCONIBLK_01039 5.6e-55 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
HCONIBLK_01040 3.1e-276
HCONIBLK_01041 0.0 S Glycosyl transferase, family 2
HCONIBLK_01042 5.4e-238 K Cell envelope-related transcriptional attenuator domain
HCONIBLK_01043 3.5e-185 K Cell envelope-related transcriptional attenuator domain
HCONIBLK_01044 1.5e-247 D FtsK/SpoIIIE family
HCONIBLK_01045 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
HCONIBLK_01046 1.7e-284 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
HCONIBLK_01047 8.8e-135 yplQ S Haemolysin-III related
HCONIBLK_01048 1.2e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HCONIBLK_01049 1.1e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
HCONIBLK_01050 2.2e-287 sdaA 4.3.1.17 E Serine dehydratase alpha chain
HCONIBLK_01051 1e-105
HCONIBLK_01053 2.6e-170 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
HCONIBLK_01054 1.4e-110 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
HCONIBLK_01055 5.6e-98 divIC D Septum formation initiator
HCONIBLK_01056 2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HCONIBLK_01057 1.1e-164 ssuC U Binding-protein-dependent transport system inner membrane component
HCONIBLK_01058 4.6e-177 P NMT1-like family
HCONIBLK_01059 9.8e-129 ssuB P ATPases associated with a variety of cellular activities
HCONIBLK_01060 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HCONIBLK_01061 4.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HCONIBLK_01062 7.1e-110 2.3.1.183 M Acetyltransferase (GNAT) domain
HCONIBLK_01063 0.0 S Uncharacterised protein family (UPF0182)
HCONIBLK_01064 6.1e-225 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
HCONIBLK_01065 4.5e-15 ybdD S Selenoprotein, putative
HCONIBLK_01066 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
HCONIBLK_01067 5.8e-32 V ABC transporter transmembrane region
HCONIBLK_01068 9.4e-72 V (ABC) transporter
HCONIBLK_01069 6.3e-99 S AAA domain, putative AbiEii toxin, Type IV TA system
HCONIBLK_01071 3.9e-81 K Winged helix DNA-binding domain
HCONIBLK_01072 1.1e-80 F Nucleoside 2-deoxyribosyltransferase
HCONIBLK_01073 1.2e-280 aspA 4.3.1.1 E Fumarase C C-terminus
HCONIBLK_01074 7.2e-40 feoA P FeoA
HCONIBLK_01075 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
HCONIBLK_01076 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HCONIBLK_01077 8.8e-181 opcA G Glucose-6-phosphate dehydrogenase subunit
HCONIBLK_01078 4.8e-148 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
HCONIBLK_01079 6.1e-282 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HCONIBLK_01080 1.5e-39 pepE 3.4.13.21 E Peptidase family S51
HCONIBLK_01081 1.4e-251 brnQ U Component of the transport system for branched-chain amino acids
HCONIBLK_01082 7.2e-194 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HCONIBLK_01083 0.0 pacS 3.6.3.54 P E1-E2 ATPase
HCONIBLK_01084 2.2e-148 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HCONIBLK_01085 1.7e-308 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
HCONIBLK_01086 4.9e-199 MA20_14895 S Conserved hypothetical protein 698
HCONIBLK_01087 8.2e-260 rutG F Permease family
HCONIBLK_01088 2.1e-215 lipA I Hydrolase, alpha beta domain protein
HCONIBLK_01089 2.8e-42
HCONIBLK_01090 2.1e-58 S Cupin 2, conserved barrel domain protein
HCONIBLK_01091 1e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HCONIBLK_01092 6.5e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HCONIBLK_01093 1.3e-270 pip 3.4.11.5 S alpha/beta hydrolase fold
HCONIBLK_01094 0.0 tcsS2 T Histidine kinase
HCONIBLK_01095 1.4e-119 K helix_turn_helix, Lux Regulon
HCONIBLK_01096 0.0 MV MacB-like periplasmic core domain
HCONIBLK_01097 8.1e-171 V ABC transporter, ATP-binding protein
HCONIBLK_01098 1.9e-96 ecfT P transmembrane transporter activity
HCONIBLK_01099 1.8e-292 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
HCONIBLK_01100 1.3e-10 metY 2.5.1.49 E Aminotransferase class-V
HCONIBLK_01101 8.8e-256 metY 2.5.1.49 E Aminotransferase class-V
HCONIBLK_01102 8.6e-167 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HCONIBLK_01103 2.2e-87 yraN L Belongs to the UPF0102 family
HCONIBLK_01104 1.1e-276 comM O Magnesium chelatase, subunit ChlI C-terminal
HCONIBLK_01105 1.3e-218 dprA 5.99.1.2 LU DNA recombination-mediator protein A
HCONIBLK_01106 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
HCONIBLK_01107 8.8e-173 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
HCONIBLK_01108 1.3e-122 safC S O-methyltransferase
HCONIBLK_01109 4.7e-151 fmt2 3.2.2.10 S Belongs to the LOG family
HCONIBLK_01110 3.7e-252 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HCONIBLK_01111 4.2e-244 patB 4.4.1.8 E Aminotransferase, class I II
HCONIBLK_01114 1.1e-250 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HCONIBLK_01115 4.3e-124 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCONIBLK_01116 1.3e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HCONIBLK_01117 1.3e-252 clcA_2 P Voltage gated chloride channel
HCONIBLK_01118 1.5e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HCONIBLK_01119 9.3e-258 rnd 3.1.13.5 J 3'-5' exonuclease
HCONIBLK_01120 9.5e-177 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCONIBLK_01121 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
HCONIBLK_01122 5.4e-32
HCONIBLK_01123 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HCONIBLK_01124 2e-227 S Peptidase dimerisation domain
HCONIBLK_01125 1.3e-120 metI P Binding-protein-dependent transport system inner membrane component
HCONIBLK_01126 6.2e-238 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCONIBLK_01127 8.6e-179 metQ P NLPA lipoprotein
HCONIBLK_01128 1.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HCONIBLK_01129 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HCONIBLK_01130 1.2e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
HCONIBLK_01131 1.8e-47 S Domain of unknown function (DUF4193)
HCONIBLK_01132 1.6e-244 S Protein of unknown function (DUF3071)
HCONIBLK_01133 2.5e-215 S Type I phosphodiesterase / nucleotide pyrophosphatase
HCONIBLK_01134 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HCONIBLK_01135 6.3e-185 glcU G Sugar transport protein
HCONIBLK_01136 0.0 lhr L DEAD DEAH box helicase
HCONIBLK_01137 2.2e-68 G Major facilitator superfamily
HCONIBLK_01138 4.7e-69 G Major facilitator superfamily
HCONIBLK_01139 1.2e-219 G Major Facilitator Superfamily
HCONIBLK_01140 2.3e-226 2.4.1.345 GT4 M Glycosyl transferase 4-like domain
HCONIBLK_01141 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
HCONIBLK_01142 1.6e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HCONIBLK_01143 4e-130
HCONIBLK_01144 2.7e-202 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
HCONIBLK_01145 0.0 pknL 2.7.11.1 KLT PASTA
HCONIBLK_01146 4.9e-139 plsC2 2.3.1.51 I Phosphate acyltransferases
HCONIBLK_01147 2.2e-99
HCONIBLK_01148 6.9e-195 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HCONIBLK_01149 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HCONIBLK_01150 7.1e-124 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HCONIBLK_01152 2.6e-112 recX S Modulates RecA activity
HCONIBLK_01153 1e-207 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HCONIBLK_01154 1e-43 S Protein of unknown function (DUF3046)
HCONIBLK_01155 8.6e-88 K Helix-turn-helix XRE-family like proteins
HCONIBLK_01156 4.2e-107 cinA 3.5.1.42 S Belongs to the CinA family
HCONIBLK_01157 7.7e-120 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HCONIBLK_01158 0.0 ftsK D FtsK SpoIIIE family protein
HCONIBLK_01159 6.8e-195 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HCONIBLK_01160 1.1e-291 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HCONIBLK_01161 1.3e-142 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
HCONIBLK_01163 8.5e-198 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
HCONIBLK_01164 6.1e-233 V ABC-2 family transporter protein
HCONIBLK_01165 7.5e-236 V ABC-2 family transporter protein
HCONIBLK_01166 4.2e-186 V ATPases associated with a variety of cellular activities
HCONIBLK_01167 1.1e-212 T Histidine kinase
HCONIBLK_01168 3.1e-116 K helix_turn_helix, Lux Regulon
HCONIBLK_01169 1.6e-151 S Protein of unknown function DUF262
HCONIBLK_01170 1.3e-251 S Protein of unknown function DUF262
HCONIBLK_01171 8.7e-124 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
HCONIBLK_01172 1.7e-35
HCONIBLK_01173 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HCONIBLK_01174 0.0 ctpE P E1-E2 ATPase
HCONIBLK_01175 7e-104
HCONIBLK_01176 7.2e-258 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HCONIBLK_01177 1.7e-137 S Protein of unknown function (DUF3159)
HCONIBLK_01178 3.3e-155 S Protein of unknown function (DUF3710)
HCONIBLK_01179 4.8e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
HCONIBLK_01180 9.8e-118
HCONIBLK_01181 0.0 dppD P Belongs to the ABC transporter superfamily
HCONIBLK_01182 4.4e-172 dppC EP N-terminal TM domain of oligopeptide transport permease C
HCONIBLK_01183 4.7e-155 dppB EP Binding-protein-dependent transport system inner membrane component
HCONIBLK_01184 0.0 E ABC transporter, substrate-binding protein, family 5
HCONIBLK_01185 6.2e-179 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HCONIBLK_01186 3.4e-149 V ABC transporter, ATP-binding protein
HCONIBLK_01187 0.0 MV MacB-like periplasmic core domain
HCONIBLK_01188 4e-40
HCONIBLK_01189 5.5e-211 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
HCONIBLK_01190 2.8e-218 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
HCONIBLK_01191 2.2e-90
HCONIBLK_01192 0.0 typA T Elongation factor G C-terminus
HCONIBLK_01193 4.8e-260 naiP U Sugar (and other) transporter
HCONIBLK_01194 2.6e-157 nrtR 3.6.1.55 F NUDIX hydrolase
HCONIBLK_01195 1.2e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HCONIBLK_01196 4.8e-168 xerD D recombinase XerD
HCONIBLK_01197 1.5e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HCONIBLK_01198 6.1e-25 rpmI J Ribosomal protein L35
HCONIBLK_01199 4.9e-101 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HCONIBLK_01200 6.8e-150 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
HCONIBLK_01201 7.4e-208 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HCONIBLK_01202 8.5e-90 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HCONIBLK_01203 6.5e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HCONIBLK_01204 1.1e-197 galM 5.1.3.3 G Aldose 1-epimerase
HCONIBLK_01205 6e-54
HCONIBLK_01206 1.5e-127 sigH K Belongs to the sigma-70 factor family. ECF subfamily
HCONIBLK_01207 4.6e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCONIBLK_01208 1.1e-200 V Acetyltransferase (GNAT) domain
HCONIBLK_01209 1.1e-297 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
HCONIBLK_01210 5e-116 gerE KT cheY-homologous receiver domain
HCONIBLK_01211 2.9e-186 2.7.13.3 T Histidine kinase
HCONIBLK_01212 1.5e-149
HCONIBLK_01213 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
HCONIBLK_01214 8.8e-98 3.6.1.55 F NUDIX domain
HCONIBLK_01215 4.8e-224 GK ROK family
HCONIBLK_01216 1.5e-169 2.7.1.4 G pfkB family carbohydrate kinase
HCONIBLK_01217 1.3e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HCONIBLK_01218 4.2e-211 int8 L Phage integrase family
HCONIBLK_01224 1.6e-28
HCONIBLK_01225 6.4e-229 T AAA domain
HCONIBLK_01230 0.0 xkdG S Caudovirus prohead serine protease
HCONIBLK_01233 0.0 P Belongs to the ABC transporter superfamily
HCONIBLK_01234 1.2e-206 dppC EP Binding-protein-dependent transport system inner membrane component
HCONIBLK_01235 8.8e-193 dppB EP Binding-protein-dependent transport system inner membrane component
HCONIBLK_01236 3.1e-59 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HCONIBLK_01237 2.9e-160 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
HCONIBLK_01238 1e-222 ftsQ 6.3.2.4 D Cell division protein FtsQ
HCONIBLK_01239 8.6e-287 murC 6.3.2.8 M Belongs to the MurCDEF family
HCONIBLK_01240 2.1e-163 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HCONIBLK_01241 1.4e-256 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
HCONIBLK_01242 3.9e-273 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HCONIBLK_01243 6.3e-207 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HCONIBLK_01244 6.7e-260 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HCONIBLK_01245 8.7e-159 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HCONIBLK_01246 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
HCONIBLK_01247 9.5e-92 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HCONIBLK_01248 3.1e-195 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HCONIBLK_01249 9.3e-86 mraZ K Belongs to the MraZ family
HCONIBLK_01250 0.0 L DNA helicase
HCONIBLK_01251 2.7e-227 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
HCONIBLK_01252 9.5e-97 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HCONIBLK_01253 2.1e-10 M LysM domain
HCONIBLK_01254 3.7e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HCONIBLK_01255 2.1e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HCONIBLK_01256 4.7e-174 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
HCONIBLK_01257 1e-279 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HCONIBLK_01258 1.2e-117 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
HCONIBLK_01259 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
HCONIBLK_01260 2.6e-263 glnA2 6.3.1.2 E glutamine synthetase
HCONIBLK_01261 1.2e-186 S Uncharacterized protein conserved in bacteria (DUF2252)
HCONIBLK_01262 4.4e-132 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
HCONIBLK_01263 2.4e-121 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HCONIBLK_01264 1.6e-124
HCONIBLK_01265 2.3e-110 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
HCONIBLK_01266 2.4e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HCONIBLK_01267 1.6e-255 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HCONIBLK_01268 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
HCONIBLK_01270 2.2e-176 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HCONIBLK_01271 1.7e-96 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HCONIBLK_01272 4.4e-33 tccB2 V DivIVA protein
HCONIBLK_01273 9.9e-43 yggT S YGGT family
HCONIBLK_01274 1.3e-79 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HCONIBLK_01275 1e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HCONIBLK_01276 2.6e-249 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HCONIBLK_01277 2.6e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
HCONIBLK_01278 1.1e-98 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HCONIBLK_01279 8.1e-293 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HCONIBLK_01280 5.1e-60 S Thiamine-binding protein
HCONIBLK_01281 1e-201 K helix_turn _helix lactose operon repressor
HCONIBLK_01282 3.6e-249 lacY P LacY proton/sugar symporter
HCONIBLK_01283 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
HCONIBLK_01284 5.4e-147 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
HCONIBLK_01285 1.2e-194 P NMT1/THI5 like
HCONIBLK_01286 4.7e-235 iunH1 3.2.2.1 F nucleoside hydrolase
HCONIBLK_01288 1.7e-153 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HCONIBLK_01289 5.7e-132 recO L Involved in DNA repair and RecF pathway recombination
HCONIBLK_01290 0.0 I acetylesterase activity
HCONIBLK_01291 2.4e-228 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HCONIBLK_01292 7e-220 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HCONIBLK_01293 1.2e-283 2.7.11.1 NU Tfp pilus assembly protein FimV
HCONIBLK_01295 4.1e-81
HCONIBLK_01296 9.1e-74 S Protein of unknown function (DUF3052)
HCONIBLK_01297 1.2e-182 lon T Belongs to the peptidase S16 family
HCONIBLK_01298 1.7e-259 S Zincin-like metallopeptidase
HCONIBLK_01299 3.4e-302 uvrD2 3.6.4.12 L DNA helicase
HCONIBLK_01300 2.7e-266 mphA S Aminoglycoside phosphotransferase
HCONIBLK_01301 2.5e-17 S Protein of unknown function (DUF3107)
HCONIBLK_01302 1.7e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
HCONIBLK_01303 2.7e-120 S Vitamin K epoxide reductase
HCONIBLK_01304 2.3e-175 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
HCONIBLK_01305 1.5e-146 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HCONIBLK_01306 3.1e-161 S Patatin-like phospholipase
HCONIBLK_01307 9.7e-137 XK27_08050 O prohibitin homologues
HCONIBLK_01308 1.6e-163 cjaA ET Bacterial periplasmic substrate-binding proteins
HCONIBLK_01309 1.8e-159 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
HCONIBLK_01310 2.7e-123 glnP E Binding-protein-dependent transport system inner membrane component
HCONIBLK_01311 4.1e-113 papP E Binding-protein-dependent transport system inner membrane component
HCONIBLK_01312 1.2e-232 mtnE 2.6.1.83 E Aminotransferase class I and II
HCONIBLK_01313 1.1e-110 metI P Psort location CytoplasmicMembrane, score 9.99
HCONIBLK_01314 8.3e-221 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HCONIBLK_01315 1e-162 metQ M NLPA lipoprotein
HCONIBLK_01316 3.9e-192 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HCONIBLK_01317 6e-128 K acetyltransferase
HCONIBLK_01318 1.5e-103 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
HCONIBLK_01321 0.0 tetP J Elongation factor G, domain IV
HCONIBLK_01322 1.9e-286 aaxC E Amino acid permease
HCONIBLK_01323 6e-117
HCONIBLK_01324 1.2e-27
HCONIBLK_01325 0.0 E ABC transporter, substrate-binding protein, family 5
HCONIBLK_01326 8.5e-260 EGP Major Facilitator Superfamily
HCONIBLK_01327 1.6e-107 pspA KT PspA/IM30 family
HCONIBLK_01328 4.4e-207 S COG1512 Beta-propeller domains of methanol dehydrogenase type
HCONIBLK_01329 8e-08 L Transposase and inactivated derivatives IS30 family
HCONIBLK_01330 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HCONIBLK_01331 2.3e-23
HCONIBLK_01332 2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
HCONIBLK_01333 4.3e-46
HCONIBLK_01334 5.6e-11
HCONIBLK_01335 0.0 V ABC transporter transmembrane region
HCONIBLK_01336 0.0 V ABC transporter, ATP-binding protein
HCONIBLK_01337 3.2e-98 K MarR family
HCONIBLK_01338 3.7e-102 S NADPH-dependent FMN reductase
HCONIBLK_01339 1.7e-98 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HCONIBLK_01342 5.8e-49
HCONIBLK_01343 2.1e-204
HCONIBLK_01344 0.0 cas3 L CRISPR-associated helicase Cas3
HCONIBLK_01345 0.0
HCONIBLK_01346 1.2e-222 S CRISPR-associated protein GSU0053 (Cas_GSU0053)
HCONIBLK_01347 9.4e-17 cas2 L CRISPR associated protein Cas2
HCONIBLK_01348 0.0 cas4 3.1.12.1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HCONIBLK_01349 6.5e-256 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
HCONIBLK_01350 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
HCONIBLK_01351 9.4e-101 yiiE S Protein of unknown function (DUF1211)
HCONIBLK_01352 3.5e-62 yiiE S Protein of unknown function (DUF1304)
HCONIBLK_01353 5.4e-121
HCONIBLK_01354 2e-148 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HCONIBLK_01355 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
HCONIBLK_01356 2.7e-233 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCONIBLK_01357 6.8e-45 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HCONIBLK_01358 5.9e-191 S Endonuclease/Exonuclease/phosphatase family
HCONIBLK_01360 1.9e-127 tmp1 S Domain of unknown function (DUF4391)
HCONIBLK_01361 1.5e-172 aspB E Aminotransferase class-V
HCONIBLK_01362 5.6e-100 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
HCONIBLK_01363 9e-300 S zinc finger
HCONIBLK_01364 1.9e-269 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
HCONIBLK_01365 2.7e-125 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HCONIBLK_01366 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HCONIBLK_01367 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
HCONIBLK_01368 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HCONIBLK_01369 5.7e-166 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HCONIBLK_01370 1.7e-134 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HCONIBLK_01371 3.5e-250 G Major Facilitator Superfamily
HCONIBLK_01372 3e-133 K -acetyltransferase
HCONIBLK_01373 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
HCONIBLK_01374 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
HCONIBLK_01375 1.9e-269 KLT Protein tyrosine kinase
HCONIBLK_01376 0.0 S Fibronectin type 3 domain
HCONIBLK_01377 7e-130 S ATPase family associated with various cellular activities (AAA)
HCONIBLK_01378 5.4e-188 S Protein of unknown function DUF58
HCONIBLK_01379 0.0 E Transglutaminase-like superfamily
HCONIBLK_01380 3.6e-93 B Belongs to the OprB family
HCONIBLK_01381 9.6e-104 T Forkhead associated domain
HCONIBLK_01382 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCONIBLK_01383 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HCONIBLK_01384 3.5e-50
HCONIBLK_01385 4.2e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
HCONIBLK_01386 1.2e-128 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HCONIBLK_01387 1.4e-251 S UPF0210 protein
HCONIBLK_01388 5.5e-43 gcvR T Belongs to the UPF0237 family
HCONIBLK_01389 7.9e-149 srtC 3.4.22.70 M Sortase family
HCONIBLK_01391 1.5e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
HCONIBLK_01392 9.1e-258 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
HCONIBLK_01393 1.3e-143 glpR K DeoR C terminal sensor domain
HCONIBLK_01394 5.7e-194 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HCONIBLK_01395 7.5e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
HCONIBLK_01396 3.2e-222 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
HCONIBLK_01397 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
HCONIBLK_01398 1e-139 glxR K helix_turn_helix, cAMP Regulatory protein
HCONIBLK_01399 3.3e-222 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
HCONIBLK_01400 1.1e-75 J TM2 domain
HCONIBLK_01401 4.2e-20
HCONIBLK_01402 4.2e-176
HCONIBLK_01403 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
HCONIBLK_01404 4.1e-289 S Uncharacterized conserved protein (DUF2183)
HCONIBLK_01405 8.4e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
HCONIBLK_01406 1.3e-215 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
HCONIBLK_01407 5e-173 mhpC I Alpha/beta hydrolase family
HCONIBLK_01408 4e-86 F Domain of unknown function (DUF4916)
HCONIBLK_01409 4.6e-67 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
HCONIBLK_01410 2e-178 S G5
HCONIBLK_01411 1.5e-286 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HCONIBLK_01412 3.3e-77
HCONIBLK_01413 1.1e-272 S Predicted membrane protein (DUF2142)
HCONIBLK_01414 2.7e-188 rfbJ M Glycosyl transferase family 2
HCONIBLK_01415 0.0 pflA S Protein of unknown function (DUF4012)
HCONIBLK_01416 5.3e-172 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HCONIBLK_01417 3e-289 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HCONIBLK_01418 4.9e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HCONIBLK_01419 3.9e-184 GT2 M Glycosyl transferase family 2
HCONIBLK_01420 1.1e-267 S Psort location CytoplasmicMembrane, score 9.99
HCONIBLK_01421 1.3e-170 S Glycosyl transferase family 2
HCONIBLK_01422 5.3e-192 S Glycosyltransferase like family 2
HCONIBLK_01423 4.9e-254
HCONIBLK_01424 5.3e-172 GT2 S Glycosyl transferase family 2
HCONIBLK_01425 1.5e-146 M Domain of unknown function (DUF4422)
HCONIBLK_01426 3.7e-165 rfbN GT2 S Glycosyltransferase like family 2
HCONIBLK_01427 3.2e-183 MA20_43635 M Capsular polysaccharide synthesis protein
HCONIBLK_01428 4.2e-239 1.1.1.22 M UDP binding domain
HCONIBLK_01429 3.1e-254 S Psort location CytoplasmicMembrane, score 9.99
HCONIBLK_01430 4.1e-197 M transferase activity, transferring glycosyl groups
HCONIBLK_01431 9.8e-163 GT2 S Glycosyl transferase family 2
HCONIBLK_01432 1.6e-288 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
HCONIBLK_01433 1.5e-45
HCONIBLK_01434 0.0 EGP Major facilitator Superfamily
HCONIBLK_01435 1.3e-241 mntH P H( )-stimulated, divalent metal cation uptake system
HCONIBLK_01436 1.1e-135 L Protein of unknown function (DUF1524)
HCONIBLK_01437 4e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HCONIBLK_01438 1e-119 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HCONIBLK_01439 2.5e-222 lspL 5.1.3.6 M epimerase dehydratase
HCONIBLK_01440 1.3e-84 pssD M Oligosaccharide biosynthesis protein Alg14 like
HCONIBLK_01441 8.9e-92 pssE M Glycosyltransferase family 28 C-terminal domain
HCONIBLK_01442 2.6e-185 GT2 S Glycosyl transferase family 2
HCONIBLK_01443 2.6e-160 GT2 S Glycosyl transferase family 2
HCONIBLK_01444 3e-204 S EpsG family
HCONIBLK_01445 0.0 cydD V ABC transporter transmembrane region
HCONIBLK_01446 0.0 fadD 6.2.1.3 I long-chain-fatty acid CoA ligase
HCONIBLK_01447 7.1e-272 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
HCONIBLK_01448 1.3e-102 3.1.3.48 T Low molecular weight phosphatase family
HCONIBLK_01449 0.0 pflA S Protein of unknown function (DUF4012)
HCONIBLK_01450 7.2e-254 wcoI DM Psort location CytoplasmicMembrane, score
HCONIBLK_01451 3.2e-57
HCONIBLK_01452 6.1e-185 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HCONIBLK_01453 6.9e-245 hom 1.1.1.3 E Homoserine dehydrogenase
HCONIBLK_01454 3.7e-301 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HCONIBLK_01455 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HCONIBLK_01456 1.2e-290 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HCONIBLK_01457 2.1e-67 psp1 3.5.99.10 J Endoribonuclease L-PSP
HCONIBLK_01458 1e-108 P Binding-protein-dependent transport system inner membrane component
HCONIBLK_01459 9.9e-185 cbpA 2.4.1.20 GT36 G Glycosyl hydrolase 36 superfamily, catalytic domain
HCONIBLK_01461 2.6e-172 trxA2 O Tetratricopeptide repeat
HCONIBLK_01462 9.9e-183
HCONIBLK_01463 1.1e-181
HCONIBLK_01464 1.4e-154 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
HCONIBLK_01465 9.1e-141 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
HCONIBLK_01466 2e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HCONIBLK_01467 3.5e-285 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HCONIBLK_01468 7.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HCONIBLK_01469 2.7e-310 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HCONIBLK_01470 8.8e-153 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCONIBLK_01471 1e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HCONIBLK_01472 1.4e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HCONIBLK_01473 1e-145 atpB C it plays a direct role in the translocation of protons across the membrane
HCONIBLK_01474 1.1e-205 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HCONIBLK_01475 7.1e-259 EGP Major facilitator Superfamily
HCONIBLK_01476 2.4e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCONIBLK_01478 3e-212
HCONIBLK_01479 2.9e-27
HCONIBLK_01480 5.1e-66
HCONIBLK_01481 2.4e-141 D ftsk spoiiie
HCONIBLK_01482 6.5e-121 S Plasmid replication protein
HCONIBLK_01483 1.4e-36
HCONIBLK_01484 4.4e-224 L HNH endonuclease
HCONIBLK_01485 1.4e-219 2.1.1.72 H Adenine-specific methyltransferase EcoRI
HCONIBLK_01486 2.9e-229 L Phage integrase family
HCONIBLK_01487 3.6e-265 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HCONIBLK_01488 1.1e-206 3.2.1.4, 3.2.1.78 GH26,GH5,GH9 G hydrolase family 5
HCONIBLK_01489 5.8e-176 yfdV S Membrane transport protein
HCONIBLK_01490 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
HCONIBLK_01491 1.2e-286 eriC P Voltage gated chloride channel
HCONIBLK_01492 0.0 M domain protein
HCONIBLK_01493 0.0 K RNA polymerase II activating transcription factor binding
HCONIBLK_01494 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
HCONIBLK_01495 2.2e-93 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HCONIBLK_01496 9e-153
HCONIBLK_01497 5.1e-139 KT Transcriptional regulatory protein, C terminal
HCONIBLK_01498 7.7e-140 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HCONIBLK_01499 1.8e-303 E Bacterial extracellular solute-binding proteins, family 5 Middle
HCONIBLK_01500 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HCONIBLK_01501 5.4e-104 K helix_turn_helix ASNC type
HCONIBLK_01502 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
HCONIBLK_01503 2.7e-311 S domain protein
HCONIBLK_01504 2.8e-311 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HCONIBLK_01505 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
HCONIBLK_01506 7.4e-52 S Protein of unknown function (DUF2469)
HCONIBLK_01507 5.1e-198 2.3.1.57 J Acetyltransferase (GNAT) domain
HCONIBLK_01508 6e-285 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCONIBLK_01509 3.2e-289 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HCONIBLK_01510 4.5e-24 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HCONIBLK_01511 4.2e-151 S ABC-type transport system involved in multi-copper enzyme maturation permease component
HCONIBLK_01512 8.4e-113 V ABC transporter
HCONIBLK_01513 1e-153 spoU 2.1.1.185 J RNA methyltransferase TrmH family
HCONIBLK_01514 3.4e-115 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HCONIBLK_01515 2.2e-260 ydbA 3.6.3.4, 3.6.3.54 P E1-E2 ATPase
HCONIBLK_01516 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HCONIBLK_01517 4.5e-157 fahA Q Fumarylacetoacetate (FAA) hydrolase family
HCONIBLK_01518 7.3e-81
HCONIBLK_01519 3.1e-306 M domain protein
HCONIBLK_01520 0.0 Q von Willebrand factor (vWF) type A domain
HCONIBLK_01521 4.6e-191 3.4.22.70 M Sortase family
HCONIBLK_01522 1.7e-151 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HCONIBLK_01523 1.1e-197 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
HCONIBLK_01524 3.1e-167 M Protein of unknown function (DUF3152)
HCONIBLK_01525 7.6e-132 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
HCONIBLK_01529 5.8e-125 T Pfam Adenylate and Guanylate cyclase catalytic domain
HCONIBLK_01530 2.2e-73 rplI J Binds to the 23S rRNA
HCONIBLK_01531 1.2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HCONIBLK_01532 2.2e-87 ssb1 L Single-stranded DNA-binding protein
HCONIBLK_01533 5.9e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
HCONIBLK_01534 1.5e-191 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HCONIBLK_01535 1.4e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HCONIBLK_01536 4.6e-269 EGP Major Facilitator Superfamily
HCONIBLK_01537 5e-168 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
HCONIBLK_01538 1.1e-197 K helix_turn _helix lactose operon repressor
HCONIBLK_01539 6.3e-237 glf 5.4.99.9 M UDP-galactopyranose mutase
HCONIBLK_01540 1.9e-208 2.4.1.303 GT2 M Glycosyl transferase family 2
HCONIBLK_01542 2.9e-198 TTHA0885 S Glycosyltransferase, group 2 family protein
HCONIBLK_01543 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HCONIBLK_01544 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
HCONIBLK_01545 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
HCONIBLK_01546 5.4e-177 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HCONIBLK_01547 0.0 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
HCONIBLK_01548 7.9e-187 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
HCONIBLK_01549 1.4e-56 S Leucine-rich repeat (LRR) protein
HCONIBLK_01550 1.1e-100 M hydrolase, family 25
HCONIBLK_01551 5.9e-134
HCONIBLK_01552 4.7e-265 S Polysaccharide pyruvyl transferase
HCONIBLK_01553 1.6e-271 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
HCONIBLK_01554 1.1e-150 rgpC U Transport permease protein
HCONIBLK_01555 0.0 2.4.1.288 GT2 S Glycosyltransferase like family 2
HCONIBLK_01557 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCONIBLK_01558 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HCONIBLK_01559 0.0 S Psort location Cytoplasmic, score 8.87
HCONIBLK_01560 9.6e-250 V ABC transporter permease
HCONIBLK_01561 1.6e-194 V ABC transporter
HCONIBLK_01562 3.2e-152 3.6.1.11, 3.6.1.40 T HD domain
HCONIBLK_01563 3.3e-169 S Glutamine amidotransferase domain
HCONIBLK_01564 0.0 kup P Transport of potassium into the cell
HCONIBLK_01565 1.7e-184 tatD L TatD related DNase
HCONIBLK_01566 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
HCONIBLK_01567 3.6e-118
HCONIBLK_01568 0.0 yknV V ABC transporter
HCONIBLK_01569 0.0 mdlA2 V ABC transporter
HCONIBLK_01570 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HCONIBLK_01571 1.3e-130
HCONIBLK_01572 6.6e-54
HCONIBLK_01573 1.1e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HCONIBLK_01574 0.0 pmt 2.4.1.109 GT39 O C-terminal four TMM region of protein-O-mannosyltransferase
HCONIBLK_01575 6.2e-159 I alpha/beta hydrolase fold
HCONIBLK_01576 4e-136 dedA S SNARE associated Golgi protein
HCONIBLK_01578 2e-128 S GyrI-like small molecule binding domain
HCONIBLK_01579 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
HCONIBLK_01580 6.2e-114 K Bacterial regulatory proteins, tetR family
HCONIBLK_01581 5.6e-129 S HAD hydrolase, family IA, variant 3
HCONIBLK_01582 5.4e-92 hspR K transcriptional regulator, MerR family
HCONIBLK_01583 2.1e-167 dnaJ1 O DnaJ molecular chaperone homology domain
HCONIBLK_01584 1.2e-94 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HCONIBLK_01585 0.0 dnaK O Heat shock 70 kDa protein
HCONIBLK_01587 1.3e-193 K Psort location Cytoplasmic, score
HCONIBLK_01588 1.8e-144 traX S TraX protein
HCONIBLK_01589 3.1e-147 S HAD-hyrolase-like
HCONIBLK_01590 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HCONIBLK_01591 7.3e-175 malG G Binding-protein-dependent transport system inner membrane component
HCONIBLK_01592 2.5e-269 malF G Binding-protein-dependent transport system inner membrane component
HCONIBLK_01593 8.7e-237 malE G Bacterial extracellular solute-binding protein
HCONIBLK_01594 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
HCONIBLK_01595 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
HCONIBLK_01596 1.1e-107 S Protein of unknown function, DUF624
HCONIBLK_01597 6.1e-154 rafG G ABC transporter permease
HCONIBLK_01598 8.8e-156 msmF G Binding-protein-dependent transport system inner membrane component
HCONIBLK_01599 1.1e-181 K Psort location Cytoplasmic, score
HCONIBLK_01600 2.7e-09 amyE G Bacterial extracellular solute-binding protein
HCONIBLK_01601 6.2e-241 amyE G Bacterial extracellular solute-binding protein
HCONIBLK_01602 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
HCONIBLK_01603 1.9e-115 G Phosphoglycerate mutase family
HCONIBLK_01604 4e-69 S Protein of unknown function (DUF4235)
HCONIBLK_01605 9.5e-141 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
HCONIBLK_01606 7.8e-44
HCONIBLK_01607 2.6e-95 iolT EGP Major facilitator Superfamily
HCONIBLK_01608 7.3e-100 nadE 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HCONIBLK_01609 2.5e-258 nadE 3.5.1.53, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HCONIBLK_01610 3e-41 relB L RelB antitoxin

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)