ORF_ID e_value Gene_name EC_number CAZy COGs Description
PMELJIPL_00001 0.0 3.2.1.78 GH26 G Glycosyl hydrolase family 26
PMELJIPL_00002 1.1e-62 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PMELJIPL_00003 0.0 gcs2 S A circularly permuted ATPgrasp
PMELJIPL_00004 2.8e-108 E Transglutaminase/protease-like homologues
PMELJIPL_00007 0.0 uvrA3 L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PMELJIPL_00008 3.2e-149 ybaJ Q ubiE/COQ5 methyltransferase family
PMELJIPL_00009 2.1e-163
PMELJIPL_00010 2e-106 XK27_04590 S NADPH-dependent FMN reductase
PMELJIPL_00011 1e-102
PMELJIPL_00012 3.3e-20
PMELJIPL_00015 2.2e-54 mazG S MazG-like family
PMELJIPL_00016 4.5e-281 L Uncharacterized conserved protein (DUF2075)
PMELJIPL_00019 1e-171
PMELJIPL_00020 3.4e-38 S Bacterial toxin of type II toxin-antitoxin system, YafQ
PMELJIPL_00021 4.1e-32 chpA T Toxic component of a toxin-antitoxin (TA) module
PMELJIPL_00022 1.3e-66 chpA T Toxic component of a toxin-antitoxin (TA) module
PMELJIPL_00023 8.3e-32 K Bacterial regulatory helix-turn-helix protein, lysR family
PMELJIPL_00024 4.6e-43 neo 2.7.1.87, 2.7.1.95 F Phosphotransferase enzyme family
PMELJIPL_00025 1e-84 dps P Belongs to the Dps family
PMELJIPL_00026 4.5e-247 ytfL P Transporter associated domain
PMELJIPL_00027 4.2e-127 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PMELJIPL_00028 2.3e-212 K helix_turn _helix lactose operon repressor
PMELJIPL_00029 1.7e-34
PMELJIPL_00030 1.7e-157 xylG 3.6.3.17 G ATPases associated with a variety of cellular activities
PMELJIPL_00031 4.8e-52
PMELJIPL_00032 3.7e-193 K helix_turn _helix lactose operon repressor
PMELJIPL_00033 4.4e-307 3.2.1.55 GH51 G arabinose metabolic process
PMELJIPL_00034 7.4e-305 araB 2.7.1.16, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
PMELJIPL_00035 5.1e-130 araD 4.1.2.17, 5.1.3.4 G Class II Aldolase and Adducin N-terminal domain
PMELJIPL_00036 4.3e-299 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
PMELJIPL_00037 7.7e-168 dkgA 1.1.1.346 S Oxidoreductase, aldo keto reductase family protein
PMELJIPL_00038 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PMELJIPL_00039 2.7e-297 yjjP S Threonine/Serine exporter, ThrE
PMELJIPL_00040 1.2e-205 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMELJIPL_00041 1.2e-47 S Protein of unknown function (DUF3073)
PMELJIPL_00042 1.4e-80 I Sterol carrier protein
PMELJIPL_00043 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PMELJIPL_00044 5.4e-36
PMELJIPL_00045 1.3e-128 gluP 3.4.21.105 S Rhomboid family
PMELJIPL_00046 6.2e-279 L ribosomal rna small subunit methyltransferase
PMELJIPL_00047 7.2e-37 crgA D Involved in cell division
PMELJIPL_00048 4.8e-140 S Bacterial protein of unknown function (DUF881)
PMELJIPL_00049 6e-224 srtA 3.4.22.70 M Sortase family
PMELJIPL_00050 3.1e-121 trpG 2.6.1.85 EH para-aminobenzoate synthase glutamine amidotransferase component II
PMELJIPL_00051 0.0 pknB 2.7.11.1 KLT Protein tyrosine kinase
PMELJIPL_00052 1.3e-193 T Protein tyrosine kinase
PMELJIPL_00053 2.2e-271 pbpA M penicillin-binding protein
PMELJIPL_00054 2.5e-290 rodA D Belongs to the SEDS family
PMELJIPL_00055 3.7e-269 pstP 3.1.3.16 T Sigma factor PP2C-like phosphatases
PMELJIPL_00056 8e-62 fhaB T Inner membrane component of T3SS, cytoplasmic domain
PMELJIPL_00057 2.3e-130 fhaA T Protein of unknown function (DUF2662)
PMELJIPL_00058 0.0 dpp4 3.4.14.5 E Dipeptidyl peptidase IV (DPP IV) N-terminal region
PMELJIPL_00059 2.1e-127 yicL EG EamA-like transporter family
PMELJIPL_00060 3.1e-214 pldB 3.1.1.5 I Serine aminopeptidase, S33
PMELJIPL_00061 5.7e-58
PMELJIPL_00062 7e-178 rrmA 2.1.1.187 Q Methyltransferase domain
PMELJIPL_00063 1.6e-28 ytgB S Transglycosylase associated protein
PMELJIPL_00064 2.2e-30 ymgJ S Transglycosylase associated protein
PMELJIPL_00066 6.2e-279 fprA 1.18.1.2, 1.19.1.1 C Pyridine nucleotide-disulphide oxidoreductase
PMELJIPL_00067 0.0 cadA P E1-E2 ATPase
PMELJIPL_00068 4.8e-284 degP O Domain present in PSD-95, Dlg, and ZO-1/2.
PMELJIPL_00069 1.1e-115 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMELJIPL_00070 1.5e-307 S Sel1-like repeats.
PMELJIPL_00071 4.6e-279 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PMELJIPL_00073 3.8e-179 htpX O Belongs to the peptidase M48B family
PMELJIPL_00074 4.8e-213 lppW 3.5.2.6 V Beta-lactamase
PMELJIPL_00075 2.5e-123 E SOS response associated peptidase (SRAP)
PMELJIPL_00076 1.1e-228 araJ EGP Major facilitator Superfamily
PMELJIPL_00077 1.1e-11 S NADPH-dependent FMN reductase
PMELJIPL_00078 7.7e-52 relB L RelB antitoxin
PMELJIPL_00079 4.9e-87 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
PMELJIPL_00080 6.5e-270 2.7.11.1 S cellulose binding
PMELJIPL_00081 2.5e-132 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMELJIPL_00082 1.3e-86 4.1.1.44 S Cupin domain
PMELJIPL_00083 8.2e-190 S Dienelactone hydrolase family
PMELJIPL_00084 4.1e-161 K Bacterial regulatory helix-turn-helix protein, lysR family
PMELJIPL_00085 9.7e-194 C Aldo/keto reductase family
PMELJIPL_00087 2.7e-249 P nitric oxide dioxygenase activity
PMELJIPL_00088 6.9e-72 C Flavodoxin
PMELJIPL_00089 4.5e-12 K transcriptional regulator, MerR family
PMELJIPL_00090 5.9e-85 fldA C Flavodoxin
PMELJIPL_00091 1.4e-144 GM NmrA-like family
PMELJIPL_00092 2.2e-204 adh 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PMELJIPL_00093 4.4e-166 K LysR substrate binding domain
PMELJIPL_00094 3.7e-254 3.5.1.104 G Polysaccharide deacetylase
PMELJIPL_00095 3e-195 fbaA 4.1.2.13 G Fructose-bisphosphate aldolase class-II
PMELJIPL_00097 5.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PMELJIPL_00098 1.2e-174 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMELJIPL_00099 6.5e-63 U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMELJIPL_00100 1.8e-230 U Belongs to the binding-protein-dependent transport system permease family
PMELJIPL_00101 9.7e-159 livM U Belongs to the binding-protein-dependent transport system permease family
PMELJIPL_00102 5.3e-160 natA E Branched-chain amino acid ATP-binding cassette transporter
PMELJIPL_00103 2.2e-148 livF E ATPases associated with a variety of cellular activities
PMELJIPL_00104 7.2e-215 natB E Receptor family ligand binding region
PMELJIPL_00105 2.4e-192 K helix_turn _helix lactose operon repressor
PMELJIPL_00106 7.4e-299 gtfA 2.4.1.329, 2.4.1.7 GH13 G Domain of unknown function (DUF1964)
PMELJIPL_00107 2.4e-295 G Transporter major facilitator family protein
PMELJIPL_00108 1.4e-106 natB E Receptor family ligand binding region
PMELJIPL_00109 8.5e-230 bccA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Biotin carboxylase C-terminal domain
PMELJIPL_00110 1.9e-183 4.2.1.48 S Domain of unknown function (DUF4392)
PMELJIPL_00111 6.8e-279 scrT G Transporter major facilitator family protein
PMELJIPL_00112 2.4e-92 S Acetyltransferase (GNAT) family
PMELJIPL_00113 2.7e-48 S Protein of unknown function (DUF1778)
PMELJIPL_00114 3.9e-15
PMELJIPL_00115 3.8e-257 yhjE EGP Sugar (and other) transporter
PMELJIPL_00116 1.1e-203 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PMELJIPL_00117 0.0 3.1.1.53 E Carbohydrate esterase, sialic acid-specific acetylesterase
PMELJIPL_00118 1.1e-219 E GDSL-like Lipase/Acylhydrolase family
PMELJIPL_00119 1.2e-279 bglA 3.2.1.21 G Glycosyl hydrolase family 1
PMELJIPL_00120 4e-190 G Bacterial extracellular solute-binding protein
PMELJIPL_00122 1.6e-212 G Bacterial extracellular solute-binding protein
PMELJIPL_00124 2.4e-163 U Binding-protein-dependent transport system inner membrane component
PMELJIPL_00125 6.7e-149 malG U Binding-protein-dependent transport system inner membrane component
PMELJIPL_00126 0.0 3.2.1.25 G beta-mannosidase
PMELJIPL_00127 2.5e-181 K helix_turn _helix lactose operon repressor
PMELJIPL_00128 2.9e-111 S Protein of unknown function, DUF624
PMELJIPL_00129 1.7e-128
PMELJIPL_00130 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
PMELJIPL_00131 9.6e-260 yihS 5.1.3.11 G N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)
PMELJIPL_00132 6.9e-133 ybbL V ATPases associated with a variety of cellular activities
PMELJIPL_00133 1.9e-145 ybbM V Uncharacterised protein family (UPF0014)
PMELJIPL_00134 6e-277 aroP E aromatic amino acid transport protein AroP K03293
PMELJIPL_00135 1.1e-127 V ABC transporter
PMELJIPL_00136 0.0 V FtsX-like permease family
PMELJIPL_00137 2.4e-281 cycA E Amino acid permease
PMELJIPL_00138 7.9e-33 V efflux transmembrane transporter activity
PMELJIPL_00139 2.8e-19 MV MacB-like periplasmic core domain
PMELJIPL_00140 6e-305 M MacB-like periplasmic core domain
PMELJIPL_00141 2e-84 V ABC transporter, ATP-binding protein
PMELJIPL_00142 1.2e-106 ydgJ K helix_turn_helix multiple antibiotic resistance protein
PMELJIPL_00143 0.0 lmrA1 V ABC transporter, ATP-binding protein
PMELJIPL_00144 0.0 lmrA2 V ABC transporter transmembrane region
PMELJIPL_00145 8.9e-268 xynD 3.2.1.8, 3.5.1.104, 3.5.1.41 G Polysaccharide deacetylase
PMELJIPL_00146 6e-123 3.6.1.27 I Acid phosphatase homologues
PMELJIPL_00147 1.6e-114 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
PMELJIPL_00148 2.7e-73
PMELJIPL_00149 9.2e-218 natB E Receptor family ligand binding region
PMELJIPL_00150 9.5e-102 K Psort location Cytoplasmic, score 8.87
PMELJIPL_00151 5e-288 pip S YhgE Pip domain protein
PMELJIPL_00152 0.0 pip S YhgE Pip domain protein
PMELJIPL_00153 2.5e-107 XK27_08585 S Hypothetical bacterial integral membrane protein (Trep_Strep)
PMELJIPL_00154 3.4e-132 XK26_04485 P Cobalt transport protein
PMELJIPL_00155 6.2e-282 G ATPases associated with a variety of cellular activities
PMELJIPL_00156 7.7e-182 adcA P ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
PMELJIPL_00157 4.3e-166 S esterase of the alpha-beta hydrolase superfamily
PMELJIPL_00158 5e-142 S esterase of the alpha-beta hydrolase superfamily
PMELJIPL_00159 1.8e-93
PMELJIPL_00161 9.6e-310 pepD E Peptidase family C69
PMELJIPL_00162 3.3e-121 icaR K Bacterial regulatory proteins, tetR family
PMELJIPL_00163 9.4e-224 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PMELJIPL_00164 9e-237 amt U Ammonium Transporter Family
PMELJIPL_00165 4.5e-55 glnB K Nitrogen regulatory protein P-II
PMELJIPL_00166 0.0 2.7.7.19, 2.7.7.59 O Nucleotidyltransferase domain
PMELJIPL_00167 2.4e-38 K sequence-specific DNA binding
PMELJIPL_00168 9.8e-258 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PMELJIPL_00169 1.8e-284 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Domain of unknown function (DUF1727)
PMELJIPL_00170 9.7e-143 cobQ S CobB/CobQ-like glutamine amidotransferase domain
PMELJIPL_00171 1.7e-52 S granule-associated protein
PMELJIPL_00172 0.0 ubiB S ABC1 family
PMELJIPL_00173 1.1e-200 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
PMELJIPL_00174 1e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PMELJIPL_00175 2e-129
PMELJIPL_00176 2.1e-204 mutT 3.6.1.13, 3.6.1.55 LT Phosphoglycerate mutase family
PMELJIPL_00177 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PMELJIPL_00178 1.2e-77 cpaE D bacterial-type flagellum organization
PMELJIPL_00179 1.3e-229 cpaF U Type II IV secretion system protein
PMELJIPL_00180 5e-107 U Type ii secretion system
PMELJIPL_00181 1.6e-97 U Type II secretion system (T2SS), protein F
PMELJIPL_00182 1.7e-39 S Protein of unknown function (DUF4244)
PMELJIPL_00183 6.5e-50 U TadE-like protein
PMELJIPL_00184 2.5e-75 S TIGRFAM helicase secretion neighborhood TadE-like protein
PMELJIPL_00185 0.0 dnaX 2.7.7.7 L DNA polymerase III subunit gamma tau
PMELJIPL_00186 1.9e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PMELJIPL_00187 6.9e-136 ask 1.1.1.3, 2.7.2.4 E Amino acid kinase family
PMELJIPL_00188 2.1e-97 askB 1.1.1.3, 2.7.2.4 E ACT domain
PMELJIPL_00189 1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PMELJIPL_00190 2.7e-120
PMELJIPL_00191 0.0 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PMELJIPL_00192 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
PMELJIPL_00193 5.9e-216 ino1 5.5.1.4 I Myo-inositol-1-phosphate synthase
PMELJIPL_00194 2.1e-219 3.6.1.27 I PAP2 superfamily
PMELJIPL_00195 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PMELJIPL_00196 2e-109 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PMELJIPL_00197 5e-211 holB 2.7.7.7 L DNA polymerase III
PMELJIPL_00198 4.3e-140 S Phosphatidylethanolamine-binding protein
PMELJIPL_00199 0.0 pepD E Peptidase family C69
PMELJIPL_00200 0.0 pepD E Peptidase family C69
PMELJIPL_00201 1.9e-222 S Domain of unknown function (DUF4143)
PMELJIPL_00202 4.1e-289 fhs 1.5.1.5, 3.5.4.9, 6.3.4.3 F Formate-tetrahydrofolate ligase
PMELJIPL_00203 6e-63 S Macrophage migration inhibitory factor (MIF)
PMELJIPL_00204 1.1e-197 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PMELJIPL_00205 7.6e-100 S GtrA-like protein
PMELJIPL_00206 6e-174
PMELJIPL_00207 2.6e-123 3.1.3.3, 3.1.3.73 G Phosphoglycerate mutase family
PMELJIPL_00208 6.8e-262 EGP Major facilitator Superfamily
PMELJIPL_00209 1.4e-294 gltX 6.1.1.17 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PMELJIPL_00212 1.8e-250 S Calcineurin-like phosphoesterase
PMELJIPL_00213 5.6e-144 ltbR K Transcriptional regulator, IclR family, C-terminal domain protein
PMELJIPL_00214 6.5e-265
PMELJIPL_00215 2.3e-127 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PMELJIPL_00216 1.4e-41 QU41_18010 2.4.2.18 K Lrp/AsnC ligand binding domain
PMELJIPL_00217 3.4e-255 nox 1.6.3.4 C Pyridine nucleotide-disulphide oxidoreductase
PMELJIPL_00218 1.1e-250 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PMELJIPL_00219 1.2e-159 plsC2 2.3.1.51 I Phosphate acyltransferases
PMELJIPL_00220 3.6e-161 gpsA 1.1.1.94 I NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus
PMELJIPL_00221 3.7e-218 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PMELJIPL_00222 4.9e-95 S Domain of unknown function (DUF4854)
PMELJIPL_00223 1.8e-177 S CAAX protease self-immunity
PMELJIPL_00224 4.4e-144 M Mechanosensitive ion channel
PMELJIPL_00225 1.9e-115 K Bacterial regulatory proteins, tetR family
PMELJIPL_00226 9.5e-233 MA20_36090 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00227 7.5e-163 S Putative ABC-transporter type IV
PMELJIPL_00228 2.9e-229 yhdR 2.6.1.1 E Psort location Cytoplasmic, score 8.87
PMELJIPL_00229 0.0 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00230 2.3e-306 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00231 1.8e-198 yegV G pfkB family carbohydrate kinase
PMELJIPL_00232 2.9e-30 rpmB J Ribosomal L28 family
PMELJIPL_00233 0.0 recG 3.6.4.12 L helicase superfamily c-terminal domain
PMELJIPL_00234 8.4e-102 rsmD 2.1.1.171 L Conserved hypothetical protein 95
PMELJIPL_00235 4.1e-158 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PMELJIPL_00236 2.7e-120 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PMELJIPL_00237 1.5e-46 CP_0960 S Belongs to the UPF0109 family
PMELJIPL_00238 7.9e-66 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PMELJIPL_00239 0.0 lacZ 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PMELJIPL_00240 8.2e-221 S Endonuclease/Exonuclease/phosphatase family
PMELJIPL_00241 1.9e-161 P Cation efflux family
PMELJIPL_00242 1.3e-264 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PMELJIPL_00243 0.0 cysS 6.1.1.16 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMELJIPL_00244 0.0 yjjK S ABC transporter
PMELJIPL_00245 3e-136 guaA1 6.3.5.2 F Peptidase C26
PMELJIPL_00246 3.4e-92 ilvN 2.2.1.6 E ACT domain
PMELJIPL_00247 0.0 ilvB 2.2.1.6 H Thiamine pyrophosphate enzyme, central domain
PMELJIPL_00248 9.5e-141 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PMELJIPL_00249 1.4e-24 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PMELJIPL_00250 9.3e-112 yceD S Uncharacterized ACR, COG1399
PMELJIPL_00251 5.8e-121
PMELJIPL_00252 1.3e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PMELJIPL_00253 1.4e-49 S Protein of unknown function (DUF3039)
PMELJIPL_00254 6e-196 yghZ C Aldo/keto reductase family
PMELJIPL_00255 1e-248 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PMELJIPL_00256 2.4e-46
PMELJIPL_00257 3.1e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
PMELJIPL_00258 8.2e-131 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PMELJIPL_00259 5.2e-245 murN 2.3.2.16 V Psort location Cytoplasmic, score 8.87
PMELJIPL_00260 4.5e-183 S Auxin Efflux Carrier
PMELJIPL_00263 6.7e-218 manC 2.7.7.13, 5.3.1.8 M Mannose-6-phosphate isomerase
PMELJIPL_00264 0.0 pgi 5.3.1.9 G Belongs to the GPI family
PMELJIPL_00265 1e-60 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PMELJIPL_00266 7.7e-137 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PMELJIPL_00267 2.4e-144 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMELJIPL_00268 1.8e-157 V ATPases associated with a variety of cellular activities
PMELJIPL_00269 8e-255 V Efflux ABC transporter, permease protein
PMELJIPL_00270 1.6e-171 dapE 3.5.1.18 E Peptidase dimerisation domain
PMELJIPL_00271 1.1e-236 dapE 3.5.1.18 E Peptidase dimerisation domain
PMELJIPL_00272 0.0 rne 3.1.26.12 J Ribonuclease E/G family
PMELJIPL_00273 5.4e-47 rplU J This protein binds to 23S rRNA in the presence of protein L20
PMELJIPL_00274 1.5e-39 rpmA J Ribosomal L27 protein
PMELJIPL_00275 2.6e-300
PMELJIPL_00276 6.7e-204 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PMELJIPL_00277 8.2e-232 aspC E DegT/DnrJ/EryC1/StrS aminotransferase family
PMELJIPL_00279 8.7e-34 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
PMELJIPL_00280 2.7e-132 nusG K Participates in transcription elongation, termination and antitermination
PMELJIPL_00281 2e-71 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PMELJIPL_00282 6e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PMELJIPL_00283 8.4e-145 QT PucR C-terminal helix-turn-helix domain
PMELJIPL_00284 4e-167 birA 2.7.1.33, 6.3.4.15 H Biotin/lipoate A/B protein ligase family
PMELJIPL_00285 1.3e-103 bioY S BioY family
PMELJIPL_00286 0.0 accA 6.3.4.14, 6.4.1.2, 6.4.1.3 I Carbamoyl-phosphate synthase L chain, ATP binding domain protein
PMELJIPL_00287 3.1e-303 pccB I Carboxyl transferase domain
PMELJIPL_00288 0.0 fas 2.3.1.179 I Beta-ketoacyl synthase, C-terminal domain
PMELJIPL_00289 5.9e-79 acpS 2.7.8.7, 3.2.1.52 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PMELJIPL_00291 6.1e-08 M O-Antigen ligase
PMELJIPL_00292 5.4e-220 3.2.1.8 G Glycosyl hydrolase family 10
PMELJIPL_00293 4e-253 tnpA L Transposase
PMELJIPL_00294 5.8e-169 tnp7109-21 L Integrase core domain
PMELJIPL_00295 1.4e-26 L Transposase
PMELJIPL_00296 2.6e-121
PMELJIPL_00297 8.4e-187 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PMELJIPL_00298 2e-49 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PMELJIPL_00299 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PMELJIPL_00301 5.6e-98 lemA S LemA family
PMELJIPL_00302 0.0 S Predicted membrane protein (DUF2207)
PMELJIPL_00303 4.1e-186 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMELJIPL_00304 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PMELJIPL_00305 9.6e-79 nrdI F Probably involved in ribonucleotide reductase function
PMELJIPL_00306 9.9e-42 nrdI F Probably involved in ribonucleotide reductase function
PMELJIPL_00307 5.9e-168 1.1.1.65 C Oxidoreductase, aldo keto reductase family protein
PMELJIPL_00308 3.7e-298 yegQ O Peptidase family U32 C-terminal domain
PMELJIPL_00309 1e-226 yfiH Q Multi-copper polyphenol oxidoreductase laccase
PMELJIPL_00310 2.9e-148 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
PMELJIPL_00311 5.1e-133 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
PMELJIPL_00312 3.1e-83 D nuclear chromosome segregation
PMELJIPL_00313 2.4e-269 pepC 3.4.22.40 E Peptidase C1-like family
PMELJIPL_00314 2.1e-218 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMELJIPL_00315 0.0 I Psort location CytoplasmicMembrane, score 9.99
PMELJIPL_00316 2.2e-240 aroG 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PMELJIPL_00317 7.4e-121 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PMELJIPL_00318 5.1e-218 senX3 2.7.13.3 T His Kinase A (phosphoacceptor) domain
PMELJIPL_00319 3.6e-131 KT Transcriptional regulatory protein, C terminal
PMELJIPL_00320 1.6e-205 pstS P Part of the ABC transporter complex PstSACB involved in phosphate import
PMELJIPL_00321 8.5e-171 pstC P probably responsible for the translocation of the substrate across the membrane
PMELJIPL_00322 8.3e-174 pstA P Phosphate transport system permease
PMELJIPL_00323 8.9e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PMELJIPL_00324 4.9e-249 pbuO S Permease family
PMELJIPL_00325 1.8e-101 ftsK D FtsK SpoIIIE family protein
PMELJIPL_00326 3.5e-32
PMELJIPL_00327 1.2e-17 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
PMELJIPL_00330 1.5e-08 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
PMELJIPL_00331 2e-120 V AAA domain (dynein-related subfamily)
PMELJIPL_00332 1.2e-121 V McrBC 5-methylcytosine restriction system component
PMELJIPL_00333 1.2e-161 P Zinc-uptake complex component A periplasmic
PMELJIPL_00334 2.1e-88 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PMELJIPL_00335 2.4e-44 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PMELJIPL_00336 9.2e-263 T Forkhead associated domain
PMELJIPL_00337 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
PMELJIPL_00338 5.6e-39
PMELJIPL_00339 7.9e-103 flgA NO SAF
PMELJIPL_00340 6.8e-32 fmdB S Putative regulatory protein
PMELJIPL_00341 2.6e-140 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
PMELJIPL_00342 2.8e-137 fthC 6.3.3.2 H 5-formyltetrahydrofolate cyclo-ligase family
PMELJIPL_00343 2.8e-195
PMELJIPL_00344 6.8e-47 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PMELJIPL_00348 1.9e-25 rpmG J Ribosomal protein L33
PMELJIPL_00349 1.7e-232 murB 1.3.1.98 M Cell wall formation
PMELJIPL_00350 1.9e-284 E aromatic amino acid transport protein AroP K03293
PMELJIPL_00351 7.6e-60 fdxA C 4Fe-4S binding domain
PMELJIPL_00352 6.8e-220 dapC E Aminotransferase class I and II
PMELJIPL_00353 2e-252 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PMELJIPL_00355 1.3e-190 MA20_16500 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PMELJIPL_00356 2.8e-114 yigZ 2.1.1.45, 3.4.13.9 S Uncharacterized protein family UPF0029
PMELJIPL_00357 2.5e-121
PMELJIPL_00358 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
PMELJIPL_00359 1.2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PMELJIPL_00360 8.5e-63 rpsI J Belongs to the universal ribosomal protein uS9 family
PMELJIPL_00361 0.0 glgX 3.2.1.196, 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PMELJIPL_00362 4.3e-208 2.7.1.2 GK transcriptional repressor of nag (N-acetylglucosamine) operon K02565
PMELJIPL_00363 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PMELJIPL_00364 1.5e-174 K Psort location Cytoplasmic, score
PMELJIPL_00365 5.6e-152 ywiC S YwiC-like protein
PMELJIPL_00366 8e-51 rpsJ J Involved in the binding of tRNA to the ribosomes
PMELJIPL_00367 3.2e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PMELJIPL_00368 6.8e-116 rplD J Forms part of the polypeptide exit tunnel
PMELJIPL_00369 2.6e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PMELJIPL_00370 1.2e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PMELJIPL_00371 1.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PMELJIPL_00372 6.7e-57 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PMELJIPL_00373 3.9e-124 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PMELJIPL_00374 2e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PMELJIPL_00375 7e-37 rpmC J Belongs to the universal ribosomal protein uL29 family
PMELJIPL_00376 8.3e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PMELJIPL_00377 8.7e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PMELJIPL_00378 3e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PMELJIPL_00379 1.7e-105 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PMELJIPL_00380 3.1e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PMELJIPL_00381 1.9e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PMELJIPL_00382 2.4e-95 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PMELJIPL_00383 1.3e-58 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PMELJIPL_00384 8.2e-94 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PMELJIPL_00385 2.5e-23 rpmD J Ribosomal protein L30p/L7e
PMELJIPL_00386 2.2e-76 rplO J binds to the 23S rRNA
PMELJIPL_00387 1.5e-250 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PMELJIPL_00388 1.6e-100 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PMELJIPL_00389 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PMELJIPL_00390 6.5e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PMELJIPL_00391 2.1e-61 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PMELJIPL_00392 5.7e-65 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PMELJIPL_00393 5.2e-184 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMELJIPL_00394 2.3e-70 rplQ J Ribosomal protein L17
PMELJIPL_00395 1.8e-147 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PMELJIPL_00397 1.9e-161
PMELJIPL_00398 9.2e-195 nusA K Participates in both transcription termination and antitermination
PMELJIPL_00399 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PMELJIPL_00400 1.1e-73 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PMELJIPL_00401 5.9e-194 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PMELJIPL_00402 7.8e-233 ribF 2.7.1.26, 2.7.7.2 H riboflavin kinase
PMELJIPL_00403 4.3e-275 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PMELJIPL_00404 5.4e-92
PMELJIPL_00406 1.8e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PMELJIPL_00407 1.6e-177 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PMELJIPL_00409 1.9e-242 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PMELJIPL_00410 6.4e-218 I Diacylglycerol kinase catalytic domain
PMELJIPL_00411 0.0 pgm 5.4.2.2 G Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II
PMELJIPL_00412 2.2e-290 S alpha beta
PMELJIPL_00413 4.8e-111 S Protein of unknown function (DUF4125)
PMELJIPL_00414 0.0 S Domain of unknown function (DUF4037)
PMELJIPL_00415 6e-126 degU K helix_turn_helix, Lux Regulon
PMELJIPL_00416 1.9e-267 tcsS3 KT PspC domain
PMELJIPL_00417 0.0 pspC KT PspC domain
PMELJIPL_00418 2.1e-93
PMELJIPL_00419 4.7e-224 metC 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PMELJIPL_00420 4.3e-127 2.5.1.49 E Cys/Met metabolism PLP-dependent enzyme
PMELJIPL_00422 0.0 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PMELJIPL_00423 2.9e-100
PMELJIPL_00424 2.6e-290 E Phospholipase B
PMELJIPL_00425 1.9e-266 pepC 3.4.22.40 E Peptidase C1-like family
PMELJIPL_00426 0.0 gadC E Amino acid permease
PMELJIPL_00427 3.5e-301 E Serine carboxypeptidase
PMELJIPL_00428 1.7e-274 puuP_1 E Amino acid permease
PMELJIPL_00429 1.3e-76 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
PMELJIPL_00430 3.4e-140 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PMELJIPL_00431 0.0 4.2.1.53 S MCRA family
PMELJIPL_00432 2.3e-62 3.5.1.10 C Zinc-binding dehydrogenase
PMELJIPL_00433 1e-122 1.6.5.5 C Zinc-binding dehydrogenase
PMELJIPL_00434 6e-282 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G Phosphomannose isomerase type I
PMELJIPL_00435 6.7e-22
PMELJIPL_00436 2.1e-223 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PMELJIPL_00437 3.3e-121 phoU P Plays a role in the regulation of phosphate uptake
PMELJIPL_00438 1.6e-210 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PMELJIPL_00439 5.6e-173 usp 3.5.1.28 CBM50 S CHAP domain
PMELJIPL_00440 6.1e-98 M NlpC/P60 family
PMELJIPL_00441 2.4e-195 T Universal stress protein family
PMELJIPL_00442 5.9e-73 attW O OsmC-like protein
PMELJIPL_00443 1.1e-174 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PMELJIPL_00444 4.1e-132 folA 1.5.1.3 H dihydrofolate reductase
PMELJIPL_00445 1.6e-99 ptpA 3.1.3.48 T low molecular weight
PMELJIPL_00446 3.6e-201 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PMELJIPL_00447 2.4e-161 trmB 2.1.1.297, 2.1.1.33, 2.4.99.12, 2.4.99.13, 2.4.99.14, 2.4.99.15 GT30 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PMELJIPL_00449 2.8e-183 XK27_05540 S DUF218 domain
PMELJIPL_00450 1.7e-187 3.1.3.5 S 5'-nucleotidase
PMELJIPL_00451 2.8e-105
PMELJIPL_00452 2.8e-293 L AAA ATPase domain
PMELJIPL_00454 2.7e-50 S Cutinase
PMELJIPL_00455 1.4e-228 S Uncharacterized protein conserved in bacteria (DUF2130)
PMELJIPL_00456 2.2e-293 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00457 1.1e-144 S Domain of unknown function (DUF4194)
PMELJIPL_00458 0.0 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00459 2.1e-235 S Psort location Cytoplasmic, score 8.87
PMELJIPL_00461 2.6e-64 yeaO K Protein of unknown function, DUF488
PMELJIPL_00462 8.2e-274 lacS G Psort location CytoplasmicMembrane, score 10.00
PMELJIPL_00463 0.0 lacL 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PMELJIPL_00464 1e-184 lacR K Transcriptional regulator, LacI family
PMELJIPL_00465 1.1e-115 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMELJIPL_00466 4.9e-61
PMELJIPL_00467 1.4e-91 S Domain of unknown function (DUF4190)
PMELJIPL_00468 6.2e-77 S Domain of unknown function (DUF4190)
PMELJIPL_00469 9.4e-205 G Bacterial extracellular solute-binding protein
PMELJIPL_00470 0.0 lacZ5 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PMELJIPL_00471 6.3e-174 G ABC transporter permease
PMELJIPL_00472 3.1e-173 G Binding-protein-dependent transport system inner membrane component
PMELJIPL_00473 1.7e-187 K Periplasmic binding protein domain
PMELJIPL_00477 1.3e-182 3.4.14.13 M Glycosyltransferase like family 2
PMELJIPL_00478 1.3e-293 S AI-2E family transporter
PMELJIPL_00479 2.9e-243 epsG M Glycosyl transferase family 21
PMELJIPL_00480 1.3e-162 natA V ATPases associated with a variety of cellular activities
PMELJIPL_00481 0.0
PMELJIPL_00482 1.1e-227 dacB 3.4.16.4 M D-Ala-D-Ala carboxypeptidase 3 (S13) family
PMELJIPL_00483 2.3e-215 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PMELJIPL_00484 2.5e-98 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PMELJIPL_00485 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PMELJIPL_00486 3.3e-142 folK 2.5.1.15, 2.6.1.85, 2.7.6.3, 3.5.4.16, 4.1.2.25 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PMELJIPL_00487 3e-113 S Protein of unknown function (DUF3180)
PMELJIPL_00488 5.8e-174 tesB I Thioesterase-like superfamily
PMELJIPL_00489 7.3e-300 yjjK S ATP-binding cassette protein, ChvD family
PMELJIPL_00490 2.7e-65 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PMELJIPL_00491 1.6e-222 metY 2.5.1.49 H Psort location Cytoplasmic, score 9.98
PMELJIPL_00492 1.3e-111 ykoE S ABC-type cobalt transport system, permease component
PMELJIPL_00493 2.2e-133
PMELJIPL_00495 1.3e-173
PMELJIPL_00496 3.2e-35 rpmE J Binds the 23S rRNA
PMELJIPL_00497 4e-272 xylA 5.3.1.5 G Belongs to the xylose isomerase family
PMELJIPL_00498 0.0 G Belongs to the glycosyl hydrolase 43 family
PMELJIPL_00499 3.2e-189 K Bacterial regulatory proteins, lacI family
PMELJIPL_00500 2e-244 msmE G ABC transporter periplasmic binding protein YcjN precursor K02027
PMELJIPL_00501 1.1e-192 MA20_14025 U Binding-protein-dependent transport system inner membrane component
PMELJIPL_00502 9.5e-158 MA20_14020 P Binding-protein-dependent transport system inner membrane component
PMELJIPL_00503 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
PMELJIPL_00504 0.0 3.1.1.53 G Glycosyl hydrolase family 2, sugar binding domain protein
PMELJIPL_00505 2e-235 CE10 I Belongs to the type-B carboxylesterase lipase family
PMELJIPL_00506 0.0 G candidate polyfunctional acetylxylan esterase b-xylosidase A-L-arabinofuranosidase, CBM9 module, glycoside hydrolase family 43 protein and carbohydrate esterase family 6 protein K01238
PMELJIPL_00507 1.7e-290 xylB 1.1.1.57, 2.7.1.17 G FGGY family of carbohydrate kinases, C-terminal domain
PMELJIPL_00508 3.6e-219 xylR GK ROK family
PMELJIPL_00509 8.6e-36 rpmE J Binds the 23S rRNA
PMELJIPL_00510 9.8e-168 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PMELJIPL_00511 3.7e-176 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PMELJIPL_00512 1e-114 ywlC 2.7.7.87 J Belongs to the SUA5 family
PMELJIPL_00513 1.3e-197 tagO 2.7.8.33, 2.7.8.35 M Glycosyl transferase family 4
PMELJIPL_00514 2.2e-290 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PMELJIPL_00515 5.7e-123 orn L 3'-to-5' exoribonuclease specific for small oligoribonucleotides
PMELJIPL_00516 2.7e-157 supH S Sucrose-6F-phosphate phosphohydrolase
PMELJIPL_00517 1.3e-276 recD2 3.6.4.12 L PIF1-like helicase
PMELJIPL_00518 2.5e-74
PMELJIPL_00519 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PMELJIPL_00520 3.2e-111 L Single-strand binding protein family
PMELJIPL_00521 0.0 pepO 3.4.24.71 O Peptidase family M13
PMELJIPL_00522 5.7e-104 S Short repeat of unknown function (DUF308)
PMELJIPL_00523 2e-130 map 3.4.11.18 E Methionine aminopeptidase
PMELJIPL_00524 3.8e-251 gltA 2.3.3.1 C Citrate synthase, C-terminal domain
PMELJIPL_00525 8.6e-84 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PMELJIPL_00526 2.1e-169 dapD 2.3.1.117 E Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA
PMELJIPL_00527 8.8e-204 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PMELJIPL_00528 3.9e-227 ftsE D Cell division ATP-binding protein FtsE
PMELJIPL_00529 9.4e-164 ftsX D Part of the ABC transporter FtsEX involved in cellular division
PMELJIPL_00530 3.3e-184 usp 3.5.1.28 CBM50 D CHAP domain protein
PMELJIPL_00531 4.2e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PMELJIPL_00532 2.3e-154 pknD ET ABC transporter, substrate-binding protein, family 3
PMELJIPL_00533 7.1e-167 pknD ET ABC transporter, substrate-binding protein, family 3
PMELJIPL_00534 4.4e-151 yecS E Binding-protein-dependent transport system inner membrane component
PMELJIPL_00535 1.1e-153 tcyC 3.6.3.21 E ATPases associated with a variety of cellular activities
PMELJIPL_00536 5.1e-181 K Psort location Cytoplasmic, score
PMELJIPL_00537 1.4e-127 K helix_turn_helix, Lux Regulon
PMELJIPL_00538 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PMELJIPL_00539 5.2e-144 rluA 5.4.99.28, 5.4.99.29 J RNA pseudouridylate synthase
PMELJIPL_00540 3.2e-68
PMELJIPL_00541 1.1e-136 coaX 2.7.1.33 H Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PMELJIPL_00542 0.0 E ABC transporter, substrate-binding protein, family 5
PMELJIPL_00543 7.8e-169 P Binding-protein-dependent transport system inner membrane component
PMELJIPL_00544 7.2e-153 EP Binding-protein-dependent transport system inner membrane component
PMELJIPL_00545 1.4e-139 P ATPases associated with a variety of cellular activities
PMELJIPL_00546 8.1e-140 sapF E ATPases associated with a variety of cellular activities
PMELJIPL_00547 2e-219 metB 2.5.1.48, 4.4.1.1, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
PMELJIPL_00548 1e-190 cbs 2.5.1.47, 4.2.1.22 E Pyridoxal-phosphate dependent enzyme
PMELJIPL_00549 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
PMELJIPL_00550 2.2e-173 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PMELJIPL_00551 6.4e-107 J Acetyltransferase (GNAT) domain
PMELJIPL_00554 1.2e-38 M1-431 S Protein of unknown function (DUF1706)
PMELJIPL_00555 5.3e-07 M1-431 S Protein of unknown function (DUF1706)
PMELJIPL_00556 1.9e-53
PMELJIPL_00557 3.1e-66 S MvaI/BcnI restriction endonuclease family
PMELJIPL_00558 2.1e-123 dcm 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
PMELJIPL_00559 4e-59 S Bacteriophage abortive infection AbiH
PMELJIPL_00560 1.4e-147 KL Domain of unknown function (DUF3427)
PMELJIPL_00561 3.8e-30 mloA S Fic/DOC family
PMELJIPL_00562 0.0 S Protein of unknown function (DUF1524)
PMELJIPL_00563 1.6e-91 gepA S Protein of unknown function (DUF4065)
PMELJIPL_00564 1.3e-90 doc S Fic/DOC family
PMELJIPL_00565 3.4e-88 XK27_03610 K Acetyltransferase (GNAT) domain
PMELJIPL_00566 3.9e-142 S 3-oxo-5-alpha-steroid 4-dehydrogenase
PMELJIPL_00567 2.7e-227 gldA 1.1.1.1, 1.1.1.6 C Iron-containing alcohol dehydrogenase
PMELJIPL_00568 6.6e-95 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PMELJIPL_00569 5.8e-102 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PMELJIPL_00570 1.1e-261 alr 5.1.1.1 M Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PMELJIPL_00571 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PMELJIPL_00572 3.7e-221 ybiR P Citrate transporter
PMELJIPL_00574 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PMELJIPL_00575 2.8e-85 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PMELJIPL_00576 1.7e-223 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PMELJIPL_00577 3.8e-69 zur P Belongs to the Fur family
PMELJIPL_00578 0.0 lysX S Uncharacterised conserved protein (DUF2156)
PMELJIPL_00579 1.2e-260 S Putative esterase
PMELJIPL_00580 3.6e-238 purD 6.3.4.13 F Belongs to the GARS family
PMELJIPL_00581 3.3e-197 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PMELJIPL_00582 9.6e-302 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PMELJIPL_00583 7e-278 umuC 2.7.7.7 L DNA-damage repair protein (DNA polymerase IV) K00961
PMELJIPL_00584 1.6e-70
PMELJIPL_00585 5.3e-197 S 50S ribosome-binding GTPase
PMELJIPL_00586 2.9e-71
PMELJIPL_00587 1e-88 S Pyridoxamine 5'-phosphate oxidase
PMELJIPL_00588 6e-103 2.7.1.196, 2.7.1.205 K sequence-specific DNA binding
PMELJIPL_00589 2.9e-27
PMELJIPL_00590 5.5e-31
PMELJIPL_00591 2.4e-45
PMELJIPL_00592 2.1e-203 S Short C-terminal domain
PMELJIPL_00593 0.0 purL 6.3.5.3 F CobB/CobQ-like glutamine amidotransferase domain
PMELJIPL_00594 8.6e-139 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PMELJIPL_00595 1.2e-233 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
PMELJIPL_00596 3.9e-234 M Glycosyl transferase 4-like domain
PMELJIPL_00597 2.7e-196 ltaE 4.1.2.48 E Beta-eliminating lyase
PMELJIPL_00599 2.7e-61 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PMELJIPL_00600 2.5e-80 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PMELJIPL_00601 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PMELJIPL_00602 1.2e-232 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PMELJIPL_00603 7.7e-123 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PMELJIPL_00604 2.6e-95
PMELJIPL_00605 5.1e-104 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PMELJIPL_00606 9.5e-80 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PMELJIPL_00607 2.8e-240 carA 6.3.5.5 F Belongs to the CarA family
PMELJIPL_00608 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase large chain, oligomerisation domain
PMELJIPL_00609 7.6e-180 pyrF 2.4.2.10, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
PMELJIPL_00610 1.2e-114 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
PMELJIPL_00611 0.0 ilvD 4.2.1.9 H Belongs to the IlvD Edd family
PMELJIPL_00612 4.2e-46 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
PMELJIPL_00613 3.1e-215 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PMELJIPL_00614 2.5e-255 cma 2.1.1.79 M Mycolic acid cyclopropane synthetase
PMELJIPL_00615 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PMELJIPL_00616 1.1e-183 fmt 2.1.1.176, 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PMELJIPL_00617 3.5e-86 serB 3.1.3.3 E haloacid dehalogenase-like hydrolase
PMELJIPL_00618 2.4e-127 apl 3.1.3.1 S SNARE associated Golgi protein
PMELJIPL_00619 1.2e-291 arc O AAA ATPase forming ring-shaped complexes
PMELJIPL_00620 3.3e-310 dop 3.5.1.119, 6.3.1.19 S Pup-ligase protein
PMELJIPL_00621 2.4e-172 hisN 3.1.3.25 G Inositol monophosphatase family
PMELJIPL_00622 2.5e-30 pup S Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation
PMELJIPL_00623 2.5e-291 pafA 6.3.1.19 O Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
PMELJIPL_00624 6.2e-42 hup L Belongs to the bacterial histone-like protein family
PMELJIPL_00626 0.0 S Lysylphosphatidylglycerol synthase TM region
PMELJIPL_00627 3e-281 purB 4.3.2.2 F Adenylosuccinate lyase C-terminal
PMELJIPL_00628 8.1e-293 S PGAP1-like protein
PMELJIPL_00630 3.6e-87
PMELJIPL_00631 7.8e-180 S von Willebrand factor (vWF) type A domain
PMELJIPL_00632 6.3e-196 S von Willebrand factor (vWF) type A domain
PMELJIPL_00633 4.5e-83
PMELJIPL_00634 9.8e-180 S Protein of unknown function DUF58
PMELJIPL_00635 4.2e-192 moxR S ATPase family associated with various cellular activities (AAA)
PMELJIPL_00636 1.5e-140 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PMELJIPL_00637 6.8e-79 S LytR cell envelope-related transcriptional attenuator
PMELJIPL_00638 1.8e-33 cspA K 'Cold-shock' DNA-binding domain
PMELJIPL_00639 3.5e-291 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PMELJIPL_00640 6.5e-42 S Proteins of 100 residues with WXG
PMELJIPL_00641 8.5e-134
PMELJIPL_00642 2.4e-133 KT Response regulator receiver domain protein
PMELJIPL_00643 0.0 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PMELJIPL_00644 4.5e-79 cspB K 'Cold-shock' DNA-binding domain
PMELJIPL_00645 2.6e-208 S Protein of unknown function (DUF3027)
PMELJIPL_00646 3.6e-116
PMELJIPL_00647 2.8e-182 uspA T Belongs to the universal stress protein A family
PMELJIPL_00648 0.0 clpC O ATPase family associated with various cellular activities (AAA)
PMELJIPL_00649 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PMELJIPL_00650 6.2e-257 hisS 6.1.1.21 J Histidyl-tRNA synthetase
PMELJIPL_00651 3e-225 3.1.26.12, 3.2.1.8 S Domain of Unknown Function (DUF349)
PMELJIPL_00652 2.1e-148 aroD S Serine aminopeptidase, S33
PMELJIPL_00653 3e-142 gluA 3.6.3.21 E ATP-binding protein of ABC transporter for glutamate K02028
PMELJIPL_00654 4.3e-155 gluB ET Belongs to the bacterial solute-binding protein 3 family
PMELJIPL_00655 5.2e-111 gluC E Binding-protein-dependent transport system inner membrane component
PMELJIPL_00656 2.1e-202 gluD E Binding-protein-dependent transport system inner membrane component
PMELJIPL_00657 9.8e-188 2.7.4.1 S Polyphosphate kinase 2 (PPK2)
PMELJIPL_00658 0.0 L DEAD DEAH box helicase
PMELJIPL_00659 1.8e-260 rarA L Recombination factor protein RarA
PMELJIPL_00660 8.2e-266 EGP Major facilitator Superfamily
PMELJIPL_00661 0.0 fadD 6.2.1.3 I AMP-binding enzyme
PMELJIPL_00662 1.4e-142 L Transposase, Mutator family
PMELJIPL_00664 1.4e-308
PMELJIPL_00665 8.2e-142 E Psort location Cytoplasmic, score 8.87
PMELJIPL_00666 2.4e-65 S Zincin-like metallopeptidase
PMELJIPL_00667 3.2e-71 yccF S Inner membrane component domain
PMELJIPL_00668 3.4e-140 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PMELJIPL_00669 2.7e-46 yhbY J CRS1_YhbY
PMELJIPL_00670 8.6e-164 yvgN 1.1.1.346 S Aldo/keto reductase family
PMELJIPL_00671 0.0 ecfA GP ABC transporter, ATP-binding protein
PMELJIPL_00672 9.9e-98 ecfA GP ABC transporter, ATP-binding protein
PMELJIPL_00673 7.7e-135 ppgK 2.7.1.2, 2.7.1.63 GK ROK family
PMELJIPL_00674 1.7e-223 E Aminotransferase class I and II
PMELJIPL_00675 4e-150 bioM P ATPases associated with a variety of cellular activities
PMELJIPL_00676 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMELJIPL_00677 0.0 S Tetratricopeptide repeat
PMELJIPL_00678 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PMELJIPL_00679 3.2e-206 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
PMELJIPL_00680 5.7e-109 ykoE S ABC-type cobalt transport system, permease component
PMELJIPL_00681 9.2e-283 glnA 6.3.1.2 E glutamine synthetase
PMELJIPL_00682 1.4e-147 S Domain of unknown function (DUF4191)
PMELJIPL_00683 3.4e-280 lpdA 1.16.1.1, 1.8.1.4 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMELJIPL_00684 9.5e-104 S Protein of unknown function (DUF3043)
PMELJIPL_00685 1.8e-264 argE E Peptidase dimerisation domain
PMELJIPL_00686 1.9e-211 2.7.13.3 T Histidine kinase
PMELJIPL_00687 7.2e-45
PMELJIPL_00688 2.2e-159 V N-Acetylmuramoyl-L-alanine amidase
PMELJIPL_00689 7.3e-225 ytrE V lipoprotein transporter activity
PMELJIPL_00690 9.3e-107 ykoE S ABC-type cobalt transport system, permease component
PMELJIPL_00691 0.0 cbiQ P ATPases associated with a variety of cellular activities
PMELJIPL_00692 1.4e-130 V ABC transporter, ATP-binding protein
PMELJIPL_00693 3.3e-164 V FtsX-like permease family
PMELJIPL_00694 1.6e-15 V FtsX-like permease family
PMELJIPL_00695 4.3e-169 IV02_28330 2.1.1.185, 2.1.1.34 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMELJIPL_00696 2.3e-177 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PMELJIPL_00697 0.0 pheT 6.1.1.20 J Phenylalanyl-tRNA synthetase beta
PMELJIPL_00698 6.9e-147
PMELJIPL_00699 3.2e-203 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PMELJIPL_00700 5.1e-207 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PMELJIPL_00701 3.3e-180 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PMELJIPL_00702 1.3e-240 argD 2.6.1.11, 2.6.1.17 E Aminotransferase class-III
PMELJIPL_00703 1.5e-183 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PMELJIPL_00704 3.1e-90 argR K Regulates arginine biosynthesis genes
PMELJIPL_00705 3.2e-239 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PMELJIPL_00706 1.1e-283 argH 4.3.2.1 E argininosuccinate lyase
PMELJIPL_00707 9.5e-155 IQ Enoyl-(Acyl carrier protein) reductase
PMELJIPL_00708 6.2e-90 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
PMELJIPL_00709 1.2e-255 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PMELJIPL_00710 4.8e-158 L Tetratricopeptide repeat
PMELJIPL_00711 1.5e-194 yutF 3.1.3.41 G Haloacid dehalogenase-like hydrolase
PMELJIPL_00712 5.4e-144 tlyA 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PMELJIPL_00713 3.9e-273 trkB P Cation transport protein
PMELJIPL_00714 2.7e-117 trkA P TrkA-N domain
PMELJIPL_00715 6.2e-182 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PMELJIPL_00716 0.0 recN L May be involved in recombinational repair of damaged DNA
PMELJIPL_00717 3.3e-129 S Haloacid dehalogenase-like hydrolase
PMELJIPL_00718 3.4e-288 thrC 4.2.3.1 E Threonine synthase N terminus
PMELJIPL_00719 3.5e-236 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PMELJIPL_00720 2.1e-114
PMELJIPL_00721 1e-127 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PMELJIPL_00722 8.2e-193 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMELJIPL_00724 5.1e-262 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PMELJIPL_00725 4.2e-71 rsfS 2.7.7.18 J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PMELJIPL_00726 1.2e-120 gpmB 3.1.3.73, 3.1.3.85 G Phosphoglycerate mutase family
PMELJIPL_00727 4.7e-78
PMELJIPL_00730 8.3e-72 pdxH S Pfam:Pyridox_oxidase
PMELJIPL_00731 3e-161 3.1.3.85, 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
PMELJIPL_00732 1.2e-169 corA P CorA-like Mg2+ transporter protein
PMELJIPL_00733 6.1e-168 ET Bacterial periplasmic substrate-binding proteins
PMELJIPL_00734 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMELJIPL_00735 8.6e-118 comEA 2.4.1.21 GT5 L Helix-hairpin-helix motif
PMELJIPL_00736 0.0 comE S Competence protein
PMELJIPL_00737 5.1e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
PMELJIPL_00738 2e-112 ydiB 2.7.1.221, 5.1.1.1 S Threonylcarbamoyl adenosine biosynthesis protein TsaE
PMELJIPL_00739 9.2e-158 yeaZ 2.3.1.234 O Glycoprotease family
PMELJIPL_00740 7.5e-91 rimI 2.3.1.128, 2.3.1.234 K FR47-like protein
PMELJIPL_00741 3.6e-196 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PMELJIPL_00743 1.9e-89
PMELJIPL_00745 3.6e-61
PMELJIPL_00746 2.4e-102 M Peptidase family M23
PMELJIPL_00747 1.6e-277 G ABC transporter substrate-binding protein
PMELJIPL_00748 9.7e-241 icd 1.1.1.42 C Belongs to the isocitrate and isopropylmalate dehydrogenases family
PMELJIPL_00749 6.2e-210 guaB 1.1.1.205 F IMP dehydrogenase family protein
PMELJIPL_00750 1.4e-19
PMELJIPL_00751 1.5e-297 fadD3 6.2.1.3 I long-chain-fatty acid CoA ligase
PMELJIPL_00752 8.3e-87 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PMELJIPL_00753 1.9e-161 rpsB J Belongs to the universal ribosomal protein uS2 family
PMELJIPL_00754 7.5e-139 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PMELJIPL_00755 1.3e-134 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PMELJIPL_00756 2.6e-92 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PMELJIPL_00757 4.6e-177 cdsA 2.7.7.41, 2.7.7.67 I Cytidylyltransferase family
PMELJIPL_00758 1.2e-230 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PMELJIPL_00759 2.9e-104 K WHG domain
PMELJIPL_00760 1e-57 nodI V ATPases associated with a variety of cellular activities
PMELJIPL_00761 2.6e-53 S ABC-2 type transporter
PMELJIPL_00762 6e-58 S ABC-2 type transporter
PMELJIPL_00763 3.9e-139 hisF 4.1.3.27 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PMELJIPL_00764 1.1e-74 hisI 3.5.4.19, 3.6.1.31 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PMELJIPL_00765 1.5e-299 trpE 4.1.3.27 E Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PMELJIPL_00766 4.9e-113 ung2 3.2.2.27 L Uracil DNA glycosylase superfamily
PMELJIPL_00768 1.3e-93 thuA G Trehalose utilisation
PMELJIPL_00769 7.9e-53 5.1.3.22 G Xylose isomerase-like TIM barrel
PMELJIPL_00771 0.0 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PMELJIPL_00772 6.4e-162 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PMELJIPL_00773 2.5e-180 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PMELJIPL_00774 2.2e-122 rpe 5.1.3.1 G Ribulose-phosphate 3-epimerase
PMELJIPL_00775 2.2e-41 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E Phosphoribosyl-ATP pyrophosphohydrolase
PMELJIPL_00776 1.2e-157 hisG 2.4.2.17 F ATP phosphoribosyltransferase
PMELJIPL_00777 1.2e-109 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMELJIPL_00778 8.7e-176 S Bacterial protein of unknown function (DUF881)
PMELJIPL_00779 4.8e-33 sbp S Protein of unknown function (DUF1290)
PMELJIPL_00780 3.5e-152 S Bacterial protein of unknown function (DUF881)
PMELJIPL_00781 1.1e-74 garA T Inner membrane component of T3SS, cytoplasmic domain
PMELJIPL_00782 3.1e-133 K helix_turn_helix, mercury resistance
PMELJIPL_00783 9.5e-68
PMELJIPL_00784 1.2e-64 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMELJIPL_00785 8.3e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PMELJIPL_00786 2.8e-139 pgp 3.1.3.18 S HAD-hyrolase-like
PMELJIPL_00787 5.1e-62 rbpA K Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters
PMELJIPL_00788 0.0 helY L DEAD DEAH box helicase
PMELJIPL_00789 5.8e-36
PMELJIPL_00790 0.0 pafB K WYL domain
PMELJIPL_00791 2.7e-282 ugpA 2.7.7.9 G UTP-glucose-1-phosphate uridylyltransferase
PMELJIPL_00792 9.9e-28 L Transposase
PMELJIPL_00793 2.4e-109 tnp7109-21 L Integrase core domain
PMELJIPL_00794 7.5e-97 L Excalibur calcium-binding domain
PMELJIPL_00795 6e-73 S EcsC protein family
PMELJIPL_00796 6.4e-19
PMELJIPL_00797 7.3e-64
PMELJIPL_00798 7.4e-137 S MvaI/BcnI restriction endonuclease family
PMELJIPL_00799 2.5e-43 L Phage integrase family
PMELJIPL_00801 0.0 der 1.1.1.399, 1.1.1.95, 2.7.4.25 F GTPase that plays an essential role in the late steps of ribosome biogenesis
PMELJIPL_00802 4.8e-145 rluB 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PMELJIPL_00803 5e-166 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
PMELJIPL_00804 5.7e-22
PMELJIPL_00805 0.0 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PMELJIPL_00806 6.8e-243
PMELJIPL_00807 3.4e-166 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
PMELJIPL_00808 3.4e-222 sucC 6.2.1.5 F Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
PMELJIPL_00809 8.5e-102 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PMELJIPL_00810 1.4e-53 yajC U Preprotein translocase subunit
PMELJIPL_00811 5e-204 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PMELJIPL_00812 1.7e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PMELJIPL_00813 2.5e-101 ruvC 3.1.22.4 L Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PMELJIPL_00814 3.6e-129 yebC K transcriptional regulatory protein
PMELJIPL_00815 5.3e-189 pimA 2.4.1.345 GT4 M Glycosyl transferases group 1
PMELJIPL_00816 1.9e-194 htrB 2.3.1.241, 2.3.1.265 M Bacterial lipid A biosynthesis acyltransferase
PMELJIPL_00817 1.1e-116 pgsA1 2.7.8.11, 2.7.8.5 I CDP-alcohol phosphatidyltransferase
PMELJIPL_00818 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PMELJIPL_00819 5e-184 S Protein of unknown function (DUF2971)
PMELJIPL_00820 2e-53 S ATPases associated with a variety of cellular activities
PMELJIPL_00822 2.9e-93 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
PMELJIPL_00823 1.1e-230
PMELJIPL_00824 0.0 3.1.26.3 S Protein of unknown function (DUF499)
PMELJIPL_00825 0.0 L DNA methylAse
PMELJIPL_00826 0.0 L SNF2 family N-terminal domain
PMELJIPL_00827 3.4e-123
PMELJIPL_00828 1.5e-61 S ABC-2 family transporter protein
PMELJIPL_00829 1.3e-103 V ATPases associated with a variety of cellular activities
PMELJIPL_00830 1.6e-68 K helix_turn_helix gluconate operon transcriptional repressor
PMELJIPL_00831 2.4e-23
PMELJIPL_00836 1.1e-157 S PAC2 family
PMELJIPL_00837 2.6e-150 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PMELJIPL_00838 4.2e-160 G Fructosamine kinase
PMELJIPL_00839 2.8e-218 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PMELJIPL_00840 6.8e-201 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PMELJIPL_00841 0.0 tkt 2.2.1.1 H Belongs to the transketolase family
PMELJIPL_00842 1.4e-201 tal 2.2.1.2 H Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PMELJIPL_00843 3e-46 S PFAM Pentapeptide repeats (8 copies)
PMELJIPL_00844 4e-231 yugH 2.6.1.1 E Aminotransferase class I and II
PMELJIPL_00845 4.6e-91 alaR K helix_turn_helix ASNC type
PMELJIPL_00846 3.3e-308 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase, class I II
PMELJIPL_00847 5.7e-160 S Sucrose-6F-phosphate phosphohydrolase
PMELJIPL_00848 4.7e-25 secG U Preprotein translocase SecG subunit
PMELJIPL_00849 2.8e-151 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PMELJIPL_00850 3.1e-223 pgk 2.7.2.3, 5.3.1.1 F Phosphoglycerate kinase
PMELJIPL_00851 4.3e-175 whiA K May be required for sporulation
PMELJIPL_00852 6e-174 rapZ S Displays ATPase and GTPase activities
PMELJIPL_00853 9.8e-177 aroE 1.1.1.25 E Shikimate dehydrogenase substrate binding domain
PMELJIPL_00854 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PMELJIPL_00855 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PMELJIPL_00856 4.5e-31 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
PMELJIPL_00857 9.8e-180 wcoO
PMELJIPL_00858 1.8e-98 mug 3.2.2.28 L Uracil DNA glycosylase superfamily
PMELJIPL_00859 2.7e-122 S Phospholipase/Carboxylesterase
PMELJIPL_00860 4.1e-300 ybiT S ABC transporter
PMELJIPL_00861 5.4e-195 cat P Cation efflux family
PMELJIPL_00862 1.4e-144 4.1.1.44 S Carboxymuconolactone decarboxylase family
PMELJIPL_00863 1.4e-183 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
PMELJIPL_00864 0.0 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PMELJIPL_00865 2e-108 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
PMELJIPL_00866 0.0 trxB1 1.8.1.9 C Thioredoxin domain
PMELJIPL_00867 1.1e-172 cpsY K Bacterial regulatory helix-turn-helix protein, lysR family
PMELJIPL_00868 1.1e-123 3.8.1.2 S Haloacid dehalogenase-like hydrolase
PMELJIPL_00869 7.7e-188 gmk 1.1.1.23, 2.7.4.8 S Protein conserved in bacteria
PMELJIPL_00870 2e-182 draG O ADP-ribosylglycohydrolase
PMELJIPL_00871 2.6e-58 ytfH K HxlR-like helix-turn-helix
PMELJIPL_00872 2.8e-51 3.6.1.55 L NUDIX domain
PMELJIPL_00873 8.9e-80 2.3.1.1 K Psort location Cytoplasmic, score 8.87
PMELJIPL_00874 1.9e-124 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMELJIPL_00875 5e-187 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PMELJIPL_00876 3.5e-157 pyrK 1.18.1.2, 1.19.1.1, 1.4.1.13, 1.4.1.14 C Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B
PMELJIPL_00877 5e-176 pyrF 2.4.2.10, 4.1.1.23 F Belongs to the OMP decarboxylase family. Type 2 subfamily
PMELJIPL_00878 3.8e-281 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PMELJIPL_00879 2e-73 pyrI 2.1.3.2 F Aspartate carbamoyltransferase regulatory chain, allosteric domain protein
PMELJIPL_00880 1.6e-177 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PMELJIPL_00881 9.8e-88 yneG S Domain of unknown function (DUF4186)
PMELJIPL_00882 0.0 glnE 2.7.7.42, 2.7.7.89 H Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
PMELJIPL_00883 1.5e-160 metF 1.5.1.20 E Methylenetetrahydrofolate reductase
PMELJIPL_00884 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PMELJIPL_00885 7.6e-100 sixA 3.6.1.55 T Phosphoglycerate mutase family
PMELJIPL_00886 1.4e-198 trmI 2.1.1.219, 2.1.1.220 J Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
PMELJIPL_00887 3.4e-160 modF 3.6.3.21, 3.6.3.34 P ATPases associated with a variety of cellular activities
PMELJIPL_00888 7.8e-246 glgA 2.4.1.342 GT4 G Starch synthase catalytic domain
PMELJIPL_00889 2.6e-88 bcp 1.11.1.15 O Redoxin
PMELJIPL_00890 4.2e-80
PMELJIPL_00891 1.7e-306 gltD 1.4.1.13, 1.4.1.14 C Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
PMELJIPL_00892 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase NADPH large subunit
PMELJIPL_00893 6.9e-261 hemN H Involved in the biosynthesis of porphyrin-containing compound
PMELJIPL_00894 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PMELJIPL_00895 3.4e-34 rpsT J Binds directly to 16S ribosomal RNA
PMELJIPL_00896 5.2e-139 S UPF0126 domain
PMELJIPL_00897 5.1e-228 ilvE 2.6.1.42 E Amino-transferase class IV
PMELJIPL_00898 1.5e-107 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PMELJIPL_00899 5e-195 S alpha beta
PMELJIPL_00900 8.8e-254 pntB 1.6.1.2 C The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
PMELJIPL_00901 1.2e-46 pntA 1.6.1.2 C 4TM region of pyridine nucleotide transhydrogenase, mitoch
PMELJIPL_00902 9.7e-203 pntAA 1.6.1.2 C NAD(P) transhydrogenase subunit alpha part 1 K00324
PMELJIPL_00903 0.0 fadD 6.2.1.3 I AMP-binding enzyme
PMELJIPL_00904 4.9e-182 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PMELJIPL_00905 7.9e-247 corC S CBS domain
PMELJIPL_00906 2.5e-103 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PMELJIPL_00907 2.4e-212 phoH T PhoH-like protein
PMELJIPL_00908 2.5e-58 hinT 2.1.1.226, 2.1.1.227 FG Scavenger mRNA decapping enzyme C-term binding
PMELJIPL_00909 3.2e-144 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PMELJIPL_00911 1.4e-164 spoU 2.1.1.185 J SpoU rRNA Methylase family
PMELJIPL_00912 2.2e-130 tnp3503b 2.7.7.7 L Transposase and inactivated derivatives
PMELJIPL_00913 3.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PMELJIPL_00914 1.7e-91 yitW S Iron-sulfur cluster assembly protein
PMELJIPL_00915 3.4e-103 iscU C SUF system FeS assembly protein, NifU family
PMELJIPL_00916 3.5e-241 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PMELJIPL_00917 2.3e-142 sufC O FeS assembly ATPase SufC
PMELJIPL_00918 5.5e-228 sufD O FeS assembly protein SufD
PMELJIPL_00919 1.4e-289 sufB O FeS assembly protein SufB
PMELJIPL_00920 0.0 S L,D-transpeptidase catalytic domain
PMELJIPL_00921 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PMELJIPL_00922 4.7e-43 M Aamy_C
PMELJIPL_00923 2e-142 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PMELJIPL_00924 2.8e-84 dexB 2.4.1.7, 3.2.1.20, 3.2.1.51, 3.2.1.70, 3.2.1.93, 3.2.1.97 GH101,GH13,GH29,GH31 M Aamy_C
PMELJIPL_00925 7e-95 amy 3.2.1.1, 3.2.1.41 CBM48,GH13 G Alpha amylase, catalytic domain
PMELJIPL_00927 2e-69 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
PMELJIPL_00928 0.0 aroK 2.7.1.71, 4.2.3.4 H Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PMELJIPL_00929 3.5e-219 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PMELJIPL_00930 8.5e-37 3.4.23.43 S Type IV leader peptidase family
PMELJIPL_00931 1.8e-199 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PMELJIPL_00932 2.7e-85 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PMELJIPL_00933 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PMELJIPL_00934 1.4e-34
PMELJIPL_00935 3.1e-63 WQ51_05790 S Bacterial protein of unknown function (DUF948)
PMELJIPL_00936 1.6e-128 pgm3 3.1.3.85 G Phosphoglycerate mutase family
PMELJIPL_00937 8.9e-63 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
PMELJIPL_00938 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PMELJIPL_00939 0.0 pcrA 3.6.4.12 L DNA helicase
PMELJIPL_00940 3e-91 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PMELJIPL_00941 6.3e-263 pbuX F Permease family
PMELJIPL_00942 1.5e-112 M Protein of unknown function (DUF3737)
PMELJIPL_00943 5.1e-27 patB 4.4.1.8 E Aminotransferase, class I II
PMELJIPL_00944 2.2e-176 patB 4.4.1.8 E Aminotransferase, class I II
PMELJIPL_00945 4.2e-186 K TRANSCRIPTIONal
PMELJIPL_00946 0.0 amyA 3.2.1.1 GH13 G Glycosyl hydrolase family 70
PMELJIPL_00947 1.3e-136 S Peptidase C26
PMELJIPL_00948 2.3e-84 proX S Aminoacyl-tRNA editing domain
PMELJIPL_00949 1.3e-95 S ABC-2 family transporter protein
PMELJIPL_00950 6.2e-165 V ATPases associated with a variety of cellular activities
PMELJIPL_00951 2.4e-66 K helix_turn_helix gluconate operon transcriptional repressor
PMELJIPL_00952 2.4e-189 K Helix-turn-helix XRE-family like proteins
PMELJIPL_00953 1e-182
PMELJIPL_00954 3.3e-140
PMELJIPL_00955 1.7e-48 4.2.99.21 E Chorismate mutase type II
PMELJIPL_00956 3.4e-160 E -acetyltransferase
PMELJIPL_00957 3.9e-71 K Acetyltransferase (GNAT) family
PMELJIPL_00958 1e-107 adk 2.7.4.3 F adenylate kinase activity
PMELJIPL_00959 2e-64 S AAA domain
PMELJIPL_00960 0.0 tetP J elongation factor G
PMELJIPL_00961 8.4e-47 insH6 L Transposase domain (DUF772)
PMELJIPL_00962 1.3e-69 K sequence-specific DNA binding
PMELJIPL_00963 3.3e-302 guaA 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PMELJIPL_00964 0.0 xfp 4.1.2.22, 4.1.2.9 G D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase
PMELJIPL_00965 0.0 pta 1.1.1.40, 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PMELJIPL_00966 5.7e-233 ackA 2.7.2.1, 2.7.2.15 H Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PMELJIPL_00967 4e-267 aroA 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PMELJIPL_00969 4.1e-231 ykiI
PMELJIPL_00970 0.0 glgX 3.2.1.68 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PMELJIPL_00971 5.7e-123 3.6.1.13 L NUDIX domain
PMELJIPL_00972 8.3e-184 yqfO 3.5.4.16 L NIF3 (NGG1p interacting factor 3)
PMELJIPL_00973 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PMELJIPL_00975 7.1e-117 pdtaR T Response regulator receiver domain protein
PMELJIPL_00976 2.6e-120 aspA 3.6.1.13 L NUDIX domain
PMELJIPL_00978 1.5e-269 pyk 2.7.1.40 G Pyruvate kinase
PMELJIPL_00979 2.5e-178 terC P Integral membrane protein, TerC family
PMELJIPL_00980 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PMELJIPL_00981 3.8e-119 coaE 2.7.1.24 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PMELJIPL_00982 3.6e-266
PMELJIPL_00983 3.1e-164 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PMELJIPL_00984 7.3e-186 P Zinc-uptake complex component A periplasmic
PMELJIPL_00985 5.1e-170 znuC P ATPases associated with a variety of cellular activities
PMELJIPL_00986 1.7e-143 znuB U ABC 3 transport family
PMELJIPL_00987 1.9e-89 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 H Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
PMELJIPL_00988 6.6e-102 carD K CarD-like/TRCF domain
PMELJIPL_00989 0.0 glgB 2.4.1.18 CBM48,GH13 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PMELJIPL_00990 8.2e-131 T Response regulator receiver domain protein
PMELJIPL_00991 1.2e-202 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PMELJIPL_00992 1.3e-145 ctsW S Phosphoribosyl transferase domain
PMELJIPL_00993 7.9e-154 cof 5.2.1.8 T Eukaryotic phosphomannomutase
PMELJIPL_00994 5.6e-55 MA20_43655 2.7.2.8 S Zincin-like metallopeptidase
PMELJIPL_00995 2.6e-275
PMELJIPL_00996 0.0 S Glycosyl transferase, family 2
PMELJIPL_00997 5.4e-238 K Cell envelope-related transcriptional attenuator domain
PMELJIPL_00998 3.5e-185 K Cell envelope-related transcriptional attenuator domain
PMELJIPL_00999 2.1e-246 D FtsK/SpoIIIE family
PMELJIPL_01000 1.9e-46 whiB K Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA
PMELJIPL_01001 1.7e-284 pdtaS 2.7.13.3 T ATPase histidine kinase DNA gyrase B HSP90 domain protein
PMELJIPL_01002 5.7e-134 yplQ S Haemolysin-III related
PMELJIPL_01003 2.6e-80 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PMELJIPL_01004 1.1e-74 fkbP 5.2.1.8 G Peptidyl-prolyl cis-trans
PMELJIPL_01005 8.3e-287 sdaA 4.3.1.17 E Serine dehydratase alpha chain
PMELJIPL_01006 1.1e-104
PMELJIPL_01008 2.6e-170 ppx 3.6.1.11, 3.6.1.40 FP Ppx/GppA phosphatase family
PMELJIPL_01009 1.4e-110 ppx2 3.6.1.11, 3.6.1.40 S Protein of unknown function (DUF501)
PMELJIPL_01010 5.6e-98 divIC D Septum formation initiator
PMELJIPL_01011 2e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PMELJIPL_01012 1.1e-164 ssuC U Binding-protein-dependent transport system inner membrane component
PMELJIPL_01013 4.6e-177 P NMT1-like family
PMELJIPL_01014 9.8e-129 ssuB P ATPases associated with a variety of cellular activities
PMELJIPL_01016 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PMELJIPL_01017 4.6e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PMELJIPL_01018 7.1e-110 2.3.1.183 M Acetyltransferase (GNAT) domain
PMELJIPL_01019 0.0 S Uncharacterised protein family (UPF0182)
PMELJIPL_01020 9.1e-221 ybbD 3.2.1.52 G Glycosyl hydrolase family 3 N-terminal domain protein
PMELJIPL_01021 1.5e-15 ybdD S Selenoprotein, putative
PMELJIPL_01022 0.0 cstA T 5TM C-terminal transporter carbon starvation CstA
PMELJIPL_01023 1.1e-30 V ABC transporter transmembrane region
PMELJIPL_01024 3.3e-73 V (ABC) transporter
PMELJIPL_01025 6.3e-99 S AAA domain, putative AbiEii toxin, Type IV TA system
PMELJIPL_01027 5.2e-87 K Winged helix DNA-binding domain
PMELJIPL_01028 3.3e-80 F Nucleoside 2-deoxyribosyltransferase
PMELJIPL_01029 2.6e-280 aspA 4.3.1.1 E Fumarase C C-terminus
PMELJIPL_01030 7.2e-40 feoA P FeoA
PMELJIPL_01031 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PMELJIPL_01032 0.0 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PMELJIPL_01033 4.3e-180 opcA G Glucose-6-phosphate dehydrogenase subunit
PMELJIPL_01034 4.8e-148 pgl 3.1.1.31 G Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase
PMELJIPL_01035 1.3e-281 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PMELJIPL_01036 1.1e-39 pepE 3.4.13.21 E Peptidase family S51
PMELJIPL_01037 1.4e-251 brnQ U Component of the transport system for branched-chain amino acids
PMELJIPL_01038 9.4e-194 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PMELJIPL_01039 0.0 pacS 3.6.3.54 P E1-E2 ATPase
PMELJIPL_01040 2.2e-148 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PMELJIPL_01041 5e-284 deaD 3.6.4.13 JKL helicase superfamily c-terminal domain
PMELJIPL_01042 2.7e-197 MA20_14895 S Conserved hypothetical protein 698
PMELJIPL_01043 4.3e-250 rutG F Permease family
PMELJIPL_01044 2.1e-215 lipA I Hydrolase, alpha beta domain protein
PMELJIPL_01045 1.3e-29
PMELJIPL_01046 2.1e-58 S Cupin 2, conserved barrel domain protein
PMELJIPL_01047 1e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PMELJIPL_01048 6.5e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PMELJIPL_01049 1.4e-269 pip 3.4.11.5 S alpha/beta hydrolase fold
PMELJIPL_01050 0.0 tcsS2 T Histidine kinase
PMELJIPL_01051 1.4e-119 K helix_turn_helix, Lux Regulon
PMELJIPL_01052 0.0 MV MacB-like periplasmic core domain
PMELJIPL_01053 8.1e-171 V ABC transporter, ATP-binding protein
PMELJIPL_01054 5.6e-96 ecfT P transmembrane transporter activity
PMELJIPL_01055 1.8e-292 3.6.3.24 P AAA domain, putative AbiEii toxin, Type IV TA system
PMELJIPL_01056 1.3e-10 metY 2.5.1.49 E Aminotransferase class-V
PMELJIPL_01057 3.4e-255 metY 2.5.1.49 E Aminotransferase class-V
PMELJIPL_01058 8.6e-167 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
PMELJIPL_01059 2.2e-87 yraN L Belongs to the UPF0102 family
PMELJIPL_01060 1.1e-276 comM O Magnesium chelatase, subunit ChlI C-terminal
PMELJIPL_01061 1.3e-218 dprA 5.99.1.2 LU DNA recombination-mediator protein A
PMELJIPL_01062 0.0 sdhA 1.3.5.1, 1.3.5.4 C Succinate dehydrogenase flavoprotein subunit
PMELJIPL_01063 8.8e-173 sdhB 1.3.5.1, 1.3.5.4 C 4Fe-4S dicluster domain
PMELJIPL_01064 1.3e-122 safC S O-methyltransferase
PMELJIPL_01065 4.7e-151 fmt2 3.2.2.10 S Belongs to the LOG family
PMELJIPL_01066 3.7e-252 nhaA P Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
PMELJIPL_01067 1.2e-243 patB 4.4.1.8 E Aminotransferase, class I II
PMELJIPL_01070 2.5e-250 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PMELJIPL_01071 4.3e-124 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PMELJIPL_01072 1.3e-113 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PMELJIPL_01073 1.4e-251 clcA_2 P Voltage gated chloride channel
PMELJIPL_01074 1.5e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PMELJIPL_01075 9.3e-258 rnd 3.1.13.5 J 3'-5' exonuclease
PMELJIPL_01076 9.5e-177 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMELJIPL_01077 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
PMELJIPL_01078 5.4e-32
PMELJIPL_01079 0.0 nadE 6.3.1.5, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMELJIPL_01080 2e-227 S Peptidase dimerisation domain
PMELJIPL_01081 1.3e-120 metI P Binding-protein-dependent transport system inner membrane component
PMELJIPL_01082 6.2e-238 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMELJIPL_01083 8.6e-179 metQ P NLPA lipoprotein
PMELJIPL_01084 4.6e-102 ppiA 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PMELJIPL_01085 0.0 relA 2.7.6.5, 3.1.7.2 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PMELJIPL_01086 1.2e-82 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PMELJIPL_01087 1.8e-47 S Domain of unknown function (DUF4193)
PMELJIPL_01088 3.1e-232 S Protein of unknown function (DUF3071)
PMELJIPL_01089 5.6e-215 S Type I phosphodiesterase / nucleotide pyrophosphatase
PMELJIPL_01090 0.0 gyrA 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
PMELJIPL_01091 4.9e-171 glcU G Sugar transport protein
PMELJIPL_01092 0.0 lhr L DEAD DEAH box helicase
PMELJIPL_01093 8.4e-68 G Major facilitator superfamily
PMELJIPL_01094 4.7e-69 G Major facilitator superfamily
PMELJIPL_01095 1.2e-219 G Major Facilitator Superfamily
PMELJIPL_01096 8.6e-226 2.4.1.345 GT4 M Glycosyl transferase 4-like domain
PMELJIPL_01097 0.0 gyrB2 5.99.1.3 L DNA topoisomerase (ATP-hydrolyzing)
PMELJIPL_01098 1.6e-186 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PMELJIPL_01099 4e-130
PMELJIPL_01100 1.4e-201 crtE 2.5.1.1, 2.5.1.10, 2.5.1.29 H Belongs to the FPP GGPP synthase family
PMELJIPL_01101 0.0 pknL 2.7.11.1 KLT PASTA
PMELJIPL_01102 2.5e-138 plsC2 2.3.1.51 I Phosphate acyltransferases
PMELJIPL_01103 2.2e-99
PMELJIPL_01104 1.2e-194 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PMELJIPL_01105 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PMELJIPL_01106 7.1e-124 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PMELJIPL_01108 2.8e-111 recX S Modulates RecA activity
PMELJIPL_01109 1.7e-207 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PMELJIPL_01110 1e-43 S Protein of unknown function (DUF3046)
PMELJIPL_01111 8.6e-88 K Helix-turn-helix XRE-family like proteins
PMELJIPL_01112 4.2e-107 cinA 3.5.1.42 S Belongs to the CinA family
PMELJIPL_01113 5e-119 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PMELJIPL_01114 0.0 ftsK D FtsK SpoIIIE family protein
PMELJIPL_01115 1.5e-194 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PMELJIPL_01116 1.1e-291 miaB 2.8.4.3 H Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PMELJIPL_01117 1.3e-142 relA2 2.7.6.5 S Region found in RelA / SpoT proteins
PMELJIPL_01119 8.5e-198 dapB 1.4.1.12, 1.4.1.16, 1.4.1.26 S Dihydrodipicolinate reductase, N-terminus
PMELJIPL_01120 1.4e-232 V ABC-2 family transporter protein
PMELJIPL_01121 7.5e-236 V ABC-2 family transporter protein
PMELJIPL_01122 1.2e-183 V ATPases associated with a variety of cellular activities
PMELJIPL_01123 6.3e-205 T Histidine kinase
PMELJIPL_01124 3.4e-115 K helix_turn_helix, Lux Regulon
PMELJIPL_01125 2.3e-306 S Protein of unknown function DUF262
PMELJIPL_01126 9.1e-138 maa 2.3.1.18, 2.3.1.79 S Bacterial transferase hexapeptide repeat protein
PMELJIPL_01127 1.7e-35
PMELJIPL_01128 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PMELJIPL_01129 0.0 ctpE P E1-E2 ATPase
PMELJIPL_01130 2.3e-117
PMELJIPL_01131 0.0 S Protein of unknown function (DUF1524)
PMELJIPL_01132 2.5e-97 L response to ionizing radiation
PMELJIPL_01133 3.9e-99 3.5.1.28 M lysozyme activity
PMELJIPL_01134 7.8e-13
PMELJIPL_01135 1.1e-121 L Resolvase, N terminal domain
PMELJIPL_01136 4.3e-46 L Resolvase, N terminal domain
PMELJIPL_01137 2e-44 S Recombinase
PMELJIPL_01138 1.6e-243 L Resolvase, N terminal domain
PMELJIPL_01140 8.2e-18
PMELJIPL_01141 4.2e-19 S Helix-turn-helix
PMELJIPL_01142 8.8e-256 trmA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PMELJIPL_01143 6.3e-137 S Protein of unknown function (DUF3159)
PMELJIPL_01144 6.3e-154 S Protein of unknown function (DUF3710)
PMELJIPL_01145 4.8e-170 exoA 3.1.11.2 L Endonuclease/Exonuclease/phosphatase family
PMELJIPL_01146 2.2e-117
PMELJIPL_01147 0.0 dppD P Belongs to the ABC transporter superfamily
PMELJIPL_01148 4.4e-172 dppC EP N-terminal TM domain of oligopeptide transport permease C
PMELJIPL_01149 4.7e-155 dppB EP Binding-protein-dependent transport system inner membrane component
PMELJIPL_01150 0.0 E ABC transporter, substrate-binding protein, family 5
PMELJIPL_01151 3.1e-178 xerC D Belongs to the 'phage' integrase family. XerC subfamily
PMELJIPL_01152 3.4e-149 V ABC transporter, ATP-binding protein
PMELJIPL_01153 0.0 MV MacB-like periplasmic core domain
PMELJIPL_01154 3.4e-39
PMELJIPL_01155 5.5e-211 tyrA 1.3.1.12, 1.3.1.43 E Prephenate dehydrogenase
PMELJIPL_01156 1.1e-217 pheA 1.3.1.12, 4.2.1.51, 5.4.99.5 E Prephenate dehydratase
PMELJIPL_01157 6.5e-90
PMELJIPL_01158 0.0 typA T Elongation factor G C-terminus
PMELJIPL_01159 1.4e-259 naiP U Sugar (and other) transporter
PMELJIPL_01160 2.6e-157 nrtR 3.6.1.55 F NUDIX hydrolase
PMELJIPL_01161 1.2e-152 soj D CobQ CobB MinD ParA nucleotide binding domain protein
PMELJIPL_01162 4.8e-168 xerD D recombinase XerD
PMELJIPL_01163 1.5e-62 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PMELJIPL_01164 6.1e-25 rpmI J Ribosomal protein L35
PMELJIPL_01165 4.9e-101 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PMELJIPL_01166 5.7e-149 2.7.6.2 H Thiamin pyrophosphokinase, vitamin B1 binding domain
PMELJIPL_01167 7.4e-208 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
PMELJIPL_01168 3.6e-88 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PMELJIPL_01169 6.5e-179 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
PMELJIPL_01170 1.1e-197 galM 5.1.3.3 G Aldose 1-epimerase
PMELJIPL_01171 6e-54
PMELJIPL_01172 1.5e-127 sigH K Belongs to the sigma-70 factor family. ECF subfamily
PMELJIPL_01173 4.6e-296 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMELJIPL_01174 1.1e-200 V Acetyltransferase (GNAT) domain
PMELJIPL_01175 5.5e-297 folC 6.3.2.12, 6.3.2.17 H Mur ligase middle domain
PMELJIPL_01176 5e-116 gerE KT cheY-homologous receiver domain
PMELJIPL_01177 2.9e-186 2.7.13.3 T Histidine kinase
PMELJIPL_01178 9e-147
PMELJIPL_01179 0.0 pepP 3.4.11.9 E Aminopeptidase P, N-terminal domain
PMELJIPL_01180 1.5e-97 3.6.1.55 F NUDIX domain
PMELJIPL_01181 4.8e-224 GK ROK family
PMELJIPL_01182 4.7e-168 2.7.1.4 G pfkB family carbohydrate kinase
PMELJIPL_01183 1.3e-84 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PMELJIPL_01185 0.0 P Belongs to the ABC transporter superfamily
PMELJIPL_01186 9.8e-201 dppC EP Binding-protein-dependent transport system inner membrane component
PMELJIPL_01187 2.6e-189 dppB EP Binding-protein-dependent transport system inner membrane component
PMELJIPL_01188 1.7e-256 ddpA E Bacterial extracellular solute-binding proteins, family 5 Middle
PMELJIPL_01189 3.8e-217 ftsQ 6.3.2.4 D Cell division protein FtsQ
PMELJIPL_01190 2.5e-286 murC 6.3.2.8 M Belongs to the MurCDEF family
PMELJIPL_01191 2.1e-163 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PMELJIPL_01192 1.4e-256 ftsW 2.4.1.227 GT28 D Belongs to the SEDS family
PMELJIPL_01193 3.9e-273 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PMELJIPL_01194 6.3e-207 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PMELJIPL_01195 2.5e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PMELJIPL_01196 8.7e-159 yqeC 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PMELJIPL_01197 0.0 ftsI 3.4.16.4 M Penicillin-binding protein, transpeptidase domain protein
PMELJIPL_01198 2.8e-91 ftsL D Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
PMELJIPL_01199 1.6e-194 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PMELJIPL_01200 9.3e-86 mraZ K Belongs to the MraZ family
PMELJIPL_01201 0.0 L DNA helicase
PMELJIPL_01202 2.7e-227 serA 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
PMELJIPL_01203 9.5e-97 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PMELJIPL_01204 2.1e-10 M LysM domain
PMELJIPL_01205 3.7e-128 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
PMELJIPL_01206 2.1e-166 czcD P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PMELJIPL_01207 1.2e-174 ldh 1.1.1.27, 1.1.1.37 C Belongs to the LDH MDH superfamily. LDH family
PMELJIPL_01208 1e-279 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PMELJIPL_01209 7.7e-117 rsmC 2.1.1.172 J Ribosomal protein L11 methyltransferase (PrmA)
PMELJIPL_01210 0.0 hrpA 3.6.4.13 L Helicase associated domain (HA2) Add an annotation
PMELJIPL_01211 2.6e-263 glnA2 6.3.1.2 E glutamine synthetase
PMELJIPL_01212 1.2e-186 S Uncharacterized protein conserved in bacteria (DUF2252)
PMELJIPL_01213 4.4e-132 hisA 5.3.1.16, 5.3.1.24 E Histidine biosynthesis protein
PMELJIPL_01214 2e-120 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PMELJIPL_01215 1.6e-124
PMELJIPL_01216 2.3e-110 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E Imidazoleglycerol-phosphate dehydratase
PMELJIPL_01217 3.2e-225 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PMELJIPL_01218 7.6e-258 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PMELJIPL_01219 0.0 dnaE 2.7.7.7 L DNA polymerase III alpha subunit
PMELJIPL_01221 1.5e-175 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PMELJIPL_01222 1.7e-96 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PMELJIPL_01223 4.4e-33 tccB2 V DivIVA protein
PMELJIPL_01224 9.9e-43 yggT S YGGT family
PMELJIPL_01225 1.3e-79 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
PMELJIPL_01226 2.3e-221 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PMELJIPL_01227 2.6e-249 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PMELJIPL_01228 2.6e-296 glyQS 6.1.1.14 J Catalyzes the attachment of glycine to tRNA(Gly)
PMELJIPL_01229 1.1e-98 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PMELJIPL_01230 2.4e-292 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
PMELJIPL_01231 5.1e-60 S Thiamine-binding protein
PMELJIPL_01232 1.1e-200 K helix_turn _helix lactose operon repressor
PMELJIPL_01233 3.6e-249 lacY P LacY proton/sugar symporter
PMELJIPL_01234 0.0 cscA 3.2.1.26 GH32 G Belongs to the glycosyl hydrolase 32 family
PMELJIPL_01235 5e-145 ytlD1 2.7.1.50 P Binding-protein-dependent transport system inner membrane component
PMELJIPL_01236 1.8e-193 P NMT1/THI5 like
PMELJIPL_01237 2e-233 iunH1 3.2.2.1 F nucleoside hydrolase
PMELJIPL_01238 2.8e-07 K Psort location Cytoplasmic, score
PMELJIPL_01239 1.1e-152 uppS 2.5.1.31, 2.5.1.86, 2.5.1.88 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PMELJIPL_01240 8.2e-131 recO L Involved in DNA repair and RecF pathway recombination
PMELJIPL_01241 0.0 I acetylesterase activity
PMELJIPL_01242 2.4e-228 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
PMELJIPL_01243 2.7e-219 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
PMELJIPL_01244 1.1e-279 2.7.11.1 NU Tfp pilus assembly protein FimV
PMELJIPL_01246 4.1e-81
PMELJIPL_01247 9.1e-74 S Protein of unknown function (DUF3052)
PMELJIPL_01248 6.7e-181 lon T Belongs to the peptidase S16 family
PMELJIPL_01249 3.1e-258 S Zincin-like metallopeptidase
PMELJIPL_01250 3.4e-302 uvrD2 3.6.4.12 L DNA helicase
PMELJIPL_01251 2.7e-266 mphA S Aminoglycoside phosphotransferase
PMELJIPL_01252 2.5e-17 S Protein of unknown function (DUF3107)
PMELJIPL_01253 1.7e-167 PPA1328 3.1.3.97 S DNA polymerase alpha chain like domain
PMELJIPL_01254 3.9e-119 S Vitamin K epoxide reductase
PMELJIPL_01255 1.2e-174 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine
PMELJIPL_01256 1.5e-146 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PMELJIPL_01257 3.1e-161 S Patatin-like phospholipase
PMELJIPL_01258 4.8e-136 XK27_08050 O prohibitin homologues
PMELJIPL_01259 1.6e-163 cjaA ET Bacterial periplasmic substrate-binding proteins
PMELJIPL_01260 1.8e-159 glnQ 3.6.3.21 E ATP binding protein of ABC transporter for glutamate aspartate K02028
PMELJIPL_01261 2.7e-123 glnP E Binding-protein-dependent transport system inner membrane component
PMELJIPL_01262 4.1e-113 papP E Binding-protein-dependent transport system inner membrane component
PMELJIPL_01263 1.8e-231 mtnE 2.6.1.83 E Aminotransferase class I and II
PMELJIPL_01264 1.1e-110 metI P Psort location CytoplasmicMembrane, score 9.99
PMELJIPL_01265 8.3e-221 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PMELJIPL_01266 6.6e-162 metQ M NLPA lipoprotein
PMELJIPL_01267 3.9e-192 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
PMELJIPL_01268 6e-128 K acetyltransferase
PMELJIPL_01269 4.4e-103 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
PMELJIPL_01272 0.0 tetP J Elongation factor G, domain IV
PMELJIPL_01273 6.8e-284 aaxC E Amino acid permease
PMELJIPL_01274 8.8e-113
PMELJIPL_01275 1.2e-27
PMELJIPL_01276 0.0 E ABC transporter, substrate-binding protein, family 5
PMELJIPL_01277 2.5e-259 EGP Major Facilitator Superfamily
PMELJIPL_01278 9.5e-108 pspA KT PspA/IM30 family
PMELJIPL_01279 7.5e-207 S COG1512 Beta-propeller domains of methanol dehydrogenase type
PMELJIPL_01280 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PMELJIPL_01281 1e-23
PMELJIPL_01282 9e-11
PMELJIPL_01283 3.8e-103 ptp3 3.1.3.48 T Tyrosine phosphatase family
PMELJIPL_01284 4.4e-115 3.2.1.4 GH5,GH9 G Cellulase (glycosyl hydrolase family 5)
PMELJIPL_01285 1.5e-11
PMELJIPL_01286 0.0 V ABC transporter transmembrane region
PMELJIPL_01287 1.2e-282 V ABC transporter, ATP-binding protein
PMELJIPL_01288 7.3e-32 K MarR family
PMELJIPL_01289 4.2e-61 S NADPH-dependent FMN reductase
PMELJIPL_01290 7.9e-50 adhB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
PMELJIPL_01292 2.9e-176 gshA 6.3.2.2 H Glutamate-cysteine ligase family 2(GCS2)
PMELJIPL_01293 0.0 hgdC I CoA enzyme activase uncharacterised domain (DUF2229)
PMELJIPL_01294 8e-100 yiiE S Protein of unknown function (DUF1211)
PMELJIPL_01295 3.5e-62 yiiE S Protein of unknown function (DUF1304)
PMELJIPL_01296 2.1e-120
PMELJIPL_01297 2e-148 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PMELJIPL_01298 0.0 nrdD 1.1.98.6 F Anaerobic ribonucleoside-triphosphate reductase
PMELJIPL_01299 8.7e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMELJIPL_01300 2e-44 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PMELJIPL_01301 1.3e-190 S Endonuclease/Exonuclease/phosphatase family
PMELJIPL_01303 1.9e-127 tmp1 S Domain of unknown function (DUF4391)
PMELJIPL_01304 9.6e-172 aspB E Aminotransferase class-V
PMELJIPL_01305 2.1e-99 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
PMELJIPL_01306 2.6e-299 S zinc finger
PMELJIPL_01307 2.1e-268 recE 2.7.7.7, 3.6.4.12 L Psort location Cytoplasmic, score
PMELJIPL_01308 4.7e-125 def 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PMELJIPL_01309 7.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PMELJIPL_01310 0.0 pepN 3.4.11.2 E Peptidase family M1 domain
PMELJIPL_01311 0.0 rnj J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PMELJIPL_01312 5.7e-166 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PMELJIPL_01313 4.9e-134 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PMELJIPL_01314 1.7e-249 G Major Facilitator Superfamily
PMELJIPL_01315 3e-133 K -acetyltransferase
PMELJIPL_01316 0.0 uvrD2 3.6.4.12 L Belongs to the helicase family. UvrD subfamily
PMELJIPL_01317 0.0 uvrD 3.6.4.12 L PD-(D/E)XK nuclease superfamily
PMELJIPL_01318 1.6e-268 KLT Protein tyrosine kinase
PMELJIPL_01319 0.0 S Fibronectin type 3 domain
PMELJIPL_01320 3.5e-129 S ATPase family associated with various cellular activities (AAA)
PMELJIPL_01321 5.4e-188 S Protein of unknown function DUF58
PMELJIPL_01322 0.0 E Transglutaminase-like superfamily
PMELJIPL_01323 1.3e-90 B Belongs to the OprB family
PMELJIPL_01324 9.6e-104 T Forkhead associated domain
PMELJIPL_01325 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMELJIPL_01326 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PMELJIPL_01327 3.5e-50
PMELJIPL_01328 9.4e-186 mutY 2.1.1.37, 2.1.3.15, 6.4.1.2 L FES
PMELJIPL_01329 1.2e-128 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PMELJIPL_01330 1.4e-251 S UPF0210 protein
PMELJIPL_01331 5.5e-43 gcvR T Belongs to the UPF0237 family
PMELJIPL_01332 8e-121 srtC 3.4.22.70 M Sortase family
PMELJIPL_01334 1.5e-233 galK 2.7.1.6, 2.7.7.12 G Belongs to the GHMP kinase family. GalK subfamily
PMELJIPL_01335 3.5e-257 galT 2.7.7.12 C Galactose-1-phosphate uridyl transferase, N-terminal domain
PMELJIPL_01336 6.3e-143 glpR K DeoR C terminal sensor domain
PMELJIPL_01337 4.9e-193 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
PMELJIPL_01338 7.5e-227 pyrD 1.3.1.14, 1.3.5.2, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor
PMELJIPL_01339 3.2e-222 namA 1.6.99.1 C NADH:flavin oxidoreductase / NADH oxidase family
PMELJIPL_01340 0.0 pon1 2.4.1.129, 3.4.16.4 GT51 M Transglycosylase
PMELJIPL_01341 1e-139 glxR K helix_turn_helix, cAMP Regulatory protein
PMELJIPL_01342 3.3e-222 lplA 6.3.1.20 H Biotin/lipoate A/B protein ligase family
PMELJIPL_01343 1.1e-75 J TM2 domain
PMELJIPL_01344 4.2e-20
PMELJIPL_01345 1.2e-175
PMELJIPL_01346 0.0 ptrB 3.4.21.83 E Peptidase, S9A B C family, catalytic domain protein
PMELJIPL_01347 3.4e-288 S Uncharacterized conserved protein (DUF2183)
PMELJIPL_01348 8.4e-72 gcvH E The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
PMELJIPL_01349 2.5e-211 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
PMELJIPL_01350 1.6e-171 mhpC I Alpha/beta hydrolase family
PMELJIPL_01351 4e-86 F Domain of unknown function (DUF4916)
PMELJIPL_01352 4.6e-67 trxA 1.8.1.8, 1.8.1.9 O Belongs to the thioredoxin family
PMELJIPL_01353 2e-178 S G5
PMELJIPL_01354 8.9e-75
PMELJIPL_01355 6e-266 S Predicted membrane protein (DUF2142)
PMELJIPL_01356 3.9e-187 rfbJ M Glycosyl transferase family 2
PMELJIPL_01357 0.0 pflA S Protein of unknown function (DUF4012)
PMELJIPL_01358 2.2e-170 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PMELJIPL_01359 3e-289 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PMELJIPL_01360 4.9e-206 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PMELJIPL_01361 2.5e-183 GT2 M Glycosyl transferase family 2
PMELJIPL_01362 9.3e-267 S Psort location CytoplasmicMembrane, score 9.99
PMELJIPL_01363 5e-170 S Glycosyl transferase family 2
PMELJIPL_01364 1.3e-190 S Glycosyltransferase like family 2
PMELJIPL_01365 2.1e-252
PMELJIPL_01366 7.7e-171 GT2 S Glycosyl transferase family 2
PMELJIPL_01367 2.8e-145 M Domain of unknown function (DUF4422)
PMELJIPL_01368 1.1e-164 rfbN GT2 S Glycosyltransferase like family 2
PMELJIPL_01369 1.1e-95 MA20_43635 M Capsular polysaccharide synthesis protein
PMELJIPL_01370 6.6e-237 1.1.1.22 M UDP binding domain
PMELJIPL_01371 4.6e-288 rfbP M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PMELJIPL_01372 1.5e-45
PMELJIPL_01373 0.0 EGP Major facilitator Superfamily
PMELJIPL_01374 8.2e-241 mntH P H( )-stimulated, divalent metal cation uptake system
PMELJIPL_01375 2e-129 L Protein of unknown function (DUF1524)
PMELJIPL_01376 2.7e-130 K helix_turn _helix lactose operon repressor
PMELJIPL_01377 1.1e-265 bga1 3.2.1.23 G Psort location Cytoplasmic, score 8.87
PMELJIPL_01378 3.3e-138 G ABC transporter permease
PMELJIPL_01379 3.4e-128 G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01380 3.4e-202 G Bacterial extracellular solute-binding protein
PMELJIPL_01381 1.2e-155 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PMELJIPL_01382 4.8e-114 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PMELJIPL_01383 0.0 cydD V ABC transporter transmembrane region
PMELJIPL_01384 0.0 fadD 6.2.1.3 I long-chain-fatty acid CoA ligase
PMELJIPL_01385 7.6e-266 maf 1.1.1.25, 2.1.1.190, 3.6.1.55, 3.6.1.67 DF Maf-like protein
PMELJIPL_01386 4.2e-43 cas2 2.7.7.7 L CRISPR-associated protein (Cas_Cas2CT1978)
PMELJIPL_01387 1.1e-131 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PMELJIPL_01388 1.9e-76 casE S CRISPR_assoc
PMELJIPL_01389 1.4e-80 casD S CRISPR-associated protein (Cas_Cas5)
PMELJIPL_01390 9.5e-113 casC L CT1975-like protein
PMELJIPL_01391 8.1e-42 casB S CRISPR-associated protein Cse2 (CRISPR_cse2)
PMELJIPL_01392 3.5e-143 casA L CRISPR system CASCADE complex protein CasA
PMELJIPL_01394 2.8e-284 cas3 L DEAD-like helicases superfamily
PMELJIPL_01395 7.4e-183 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PMELJIPL_01396 6.9e-245 hom 1.1.1.3 E Homoserine dehydrogenase
PMELJIPL_01397 5.4e-300 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PMELJIPL_01398 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
PMELJIPL_01399 2.3e-289 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
PMELJIPL_01400 2.1e-67 psp1 3.5.99.10 J Endoribonuclease L-PSP
PMELJIPL_01401 1e-108 P Binding-protein-dependent transport system inner membrane component
PMELJIPL_01402 9.9e-185 cbpA 2.4.1.20 GT36 G Glycosyl hydrolase 36 superfamily, catalytic domain
PMELJIPL_01404 1.6e-169 trxA2 O Tetratricopeptide repeat
PMELJIPL_01405 9.9e-183
PMELJIPL_01406 2.5e-181
PMELJIPL_01407 1.9e-148 fkbB 5.2.1.8 M FKBP-type peptidyl-prolyl cis-trans isomerase
PMELJIPL_01408 3.8e-139 nucS L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
PMELJIPL_01409 2e-49 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PMELJIPL_01410 3.5e-285 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PMELJIPL_01411 7.7e-166 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PMELJIPL_01412 2.7e-310 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PMELJIPL_01413 8.8e-153 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMELJIPL_01414 1e-61 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PMELJIPL_01415 1.4e-31 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PMELJIPL_01416 1e-145 atpB C it plays a direct role in the translocation of protons across the membrane
PMELJIPL_01417 1.6e-204 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PMELJIPL_01418 9.2e-259 EGP Major facilitator Superfamily
PMELJIPL_01419 2.4e-183 rihB 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PMELJIPL_01421 3.6e-265 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
PMELJIPL_01422 5.5e-206 3.2.1.4, 3.2.1.78 GH26,GH5,GH9 G hydrolase family 5
PMELJIPL_01423 5.8e-176 yfdV S Membrane transport protein
PMELJIPL_01424 0.0 oxc 4.1.1.8 EH Thiamine pyrophosphate enzyme, central domain
PMELJIPL_01425 1.2e-286 eriC P Voltage gated chloride channel
PMELJIPL_01426 0.0 M domain protein
PMELJIPL_01427 0.0 K RNA polymerase II activating transcription factor binding
PMELJIPL_01428 0.0 glgE 2.4.99.16 GH13 G Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB
PMELJIPL_01429 2.2e-93 ppa 3.6.1.1 C Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PMELJIPL_01430 1e-151
PMELJIPL_01431 5.1e-139 KT Transcriptional regulatory protein, C terminal
PMELJIPL_01432 7.7e-140 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PMELJIPL_01434 4.9e-301 E Bacterial extracellular solute-binding proteins, family 5 Middle
PMELJIPL_01435 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PMELJIPL_01436 5.4e-104 K helix_turn_helix ASNC type
PMELJIPL_01437 1e-63 tyrA 5.4.99.5 E Chorismate mutase type II
PMELJIPL_01438 0.0 S domain protein
PMELJIPL_01439 2.8e-311 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
PMELJIPL_01440 0.0 5.4.99.9 H Flavin containing amine oxidoreductase
PMELJIPL_01441 7.4e-52 S Protein of unknown function (DUF2469)
PMELJIPL_01442 1.1e-203 2.3.1.57 J Acetyltransferase (GNAT) domain
PMELJIPL_01443 3.9e-284 gatB 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMELJIPL_01444 1.6e-288 gatA 6.3.5.6, 6.3.5.7 F Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PMELJIPL_01445 4.5e-24 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PMELJIPL_01446 4.7e-150 S ABC-type transport system involved in multi-copper enzyme maturation permease component
PMELJIPL_01447 8.4e-113 V ABC transporter
PMELJIPL_01448 5.6e-152 spoU 2.1.1.185 J RNA methyltransferase TrmH family
PMELJIPL_01449 3.4e-115 pyrE 2.4.2.10 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PMELJIPL_01450 2.6e-258 ydbA 3.6.3.4, 3.6.3.54 P E1-E2 ATPase
PMELJIPL_01451 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
PMELJIPL_01452 6.5e-156 fahA Q Fumarylacetoacetate (FAA) hydrolase family
PMELJIPL_01453 5.3e-79
PMELJIPL_01454 2.5e-84 M domain protein
PMELJIPL_01455 0.0 Q von Willebrand factor (vWF) type A domain
PMELJIPL_01456 1.5e-186 3.4.22.70 M Sortase family
PMELJIPL_01457 1.6e-149 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PMELJIPL_01458 1.1e-200 gluQ 6.1.1.17 J Belongs to the class-I aminoacyl-tRNA synthetase family
PMELJIPL_01459 2.7e-34 M Protein of unknown function (DUF3152)
PMELJIPL_01460 1.3e-131 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PMELJIPL_01464 1.1e-143 T Pfam Adenylate and Guanylate cyclase catalytic domain
PMELJIPL_01465 2.2e-73 rplI J Binds to the 23S rRNA
PMELJIPL_01466 1.2e-36 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PMELJIPL_01467 2.2e-87 ssb1 L Single-stranded DNA-binding protein
PMELJIPL_01468 5.9e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
PMELJIPL_01469 5.3e-192 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PMELJIPL_01470 1.4e-173 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PMELJIPL_01471 4.6e-269 EGP Major Facilitator Superfamily
PMELJIPL_01472 5e-168 iunH2 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
PMELJIPL_01473 1.9e-197 K helix_turn _helix lactose operon repressor
PMELJIPL_01474 2.4e-236 glf 5.4.99.9 M UDP-galactopyranose mutase
PMELJIPL_01475 8.1e-207 2.4.1.303 GT2 M Glycosyl transferase family 2
PMELJIPL_01477 2.5e-197 TTHA0885 S Glycosyltransferase, group 2 family protein
PMELJIPL_01478 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
PMELJIPL_01479 0.0 XK27_08315 M Psort location CytoplasmicMembrane, score 9.26
PMELJIPL_01480 0.0 glfT 2.4.1.288 GT2 S Glycosyltransferase like family 2
PMELJIPL_01481 3.1e-164 lytC 3.2.1.17, 3.2.1.96 M Glycosyl hydrolases family 25
PMELJIPL_01482 1.4e-11 S Tetratricopeptide repeat
PMELJIPL_01483 3.2e-26 S Tetratricopeptide repeat
PMELJIPL_01484 2.5e-226 rgpD 3.6.3.38 GM ABC transporter, ATP-binding protein
PMELJIPL_01485 7e-150 rgpC U Transport permease protein
PMELJIPL_01486 0.0 2.4.1.288 GT2 S Glycosyltransferase like family 2
PMELJIPL_01488 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMELJIPL_01489 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
PMELJIPL_01490 2.7e-19 M Excalibur calcium-binding domain
PMELJIPL_01491 0.0 S Psort location Cytoplasmic, score 8.87
PMELJIPL_01492 3.6e-249 V ABC transporter permease
PMELJIPL_01493 1.2e-186 V ABC transporter
PMELJIPL_01494 3.2e-152 3.6.1.11, 3.6.1.40 T HD domain
PMELJIPL_01495 3.3e-169 S Glutamine amidotransferase domain
PMELJIPL_01496 0.0 kup P Transport of potassium into the cell
PMELJIPL_01497 1.5e-183 tatD L TatD related DNase
PMELJIPL_01498 0.0 rafA 3.2.1.22 G Psort location Cytoplasmic, score 8.87
PMELJIPL_01499 3.6e-118
PMELJIPL_01500 0.0 yknV V ABC transporter
PMELJIPL_01501 0.0 mdlA2 V ABC transporter
PMELJIPL_01503 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PMELJIPL_01504 1.7e-130
PMELJIPL_01505 8.9e-51
PMELJIPL_01506 1.1e-172 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PMELJIPL_01507 0.0 pmt 2.4.1.109 GT39 O C-terminal four TMM region of protein-O-mannosyltransferase
PMELJIPL_01508 2.6e-157 I alpha/beta hydrolase fold
PMELJIPL_01509 5.2e-136 dedA S SNARE associated Golgi protein
PMELJIPL_01511 4.8e-136 S GyrI-like small molecule binding domain
PMELJIPL_01512 0.0 bgl2 3.2.1.21 GH3 G Fibronectin type III-like domain
PMELJIPL_01513 6.2e-114 K Bacterial regulatory proteins, tetR family
PMELJIPL_01514 9.6e-129 S HAD hydrolase, family IA, variant 3
PMELJIPL_01515 5.4e-92 hspR K transcriptional regulator, MerR family
PMELJIPL_01516 3.6e-167 dnaJ1 O DnaJ molecular chaperone homology domain
PMELJIPL_01517 1.2e-94 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PMELJIPL_01518 0.0 dnaK O Heat shock 70 kDa protein
PMELJIPL_01520 1.1e-192 K Psort location Cytoplasmic, score
PMELJIPL_01521 1.8e-144 traX S TraX protein
PMELJIPL_01522 3.1e-147 S HAD-hyrolase-like
PMELJIPL_01523 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
PMELJIPL_01524 7.3e-175 malG G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01525 1.3e-268 malF G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01526 8.7e-237 malE G Bacterial extracellular solute-binding protein
PMELJIPL_01527 0.0 malL 3.2.1.1, 5.4.99.16 GH13 G Alpha-amylase domain
PMELJIPL_01528 0.0 malQ 2.4.1.18, 2.4.1.25, 3.2.1.196, 5.4.99.15 CBM48,GH13,GH77 G 4-alpha-glucanotransferase
PMELJIPL_01529 1.1e-107 S Protein of unknown function, DUF624
PMELJIPL_01530 2.3e-153 rafG G ABC transporter permease
PMELJIPL_01531 8.8e-156 msmF G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01532 1.1e-181 K Psort location Cytoplasmic, score
PMELJIPL_01533 1e-256 amyE G Bacterial extracellular solute-binding protein
PMELJIPL_01534 0.0 3.2.1.10, 3.2.1.20, 3.2.1.93 GH13,GH31 G Alpha-amylase domain
PMELJIPL_01535 1.9e-115 G Phosphoglycerate mutase family
PMELJIPL_01536 4e-69 S Protein of unknown function (DUF4235)
PMELJIPL_01537 8e-140 nfrA 1.5.1.38, 1.5.1.39 C Nitroreductase family
PMELJIPL_01538 7.8e-44
PMELJIPL_01539 7.5e-46 iolT EGP Major facilitator Superfamily
PMELJIPL_01540 6e-33 iolT EGP Major facilitator Superfamily
PMELJIPL_01541 5.8e-97 nadE 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMELJIPL_01542 2.4e-231 nadE 3.5.1.53, 6.3.5.1 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PMELJIPL_01543 3e-41 relB L RelB antitoxin
PMELJIPL_01544 9.9e-269 G Psort location CytoplasmicMembrane, score 10.00
PMELJIPL_01545 0.0 3.2.1.185 GH127 S Beta-L-arabinofuranosidase, GH127
PMELJIPL_01546 9.9e-202 K Periplasmic binding protein domain
PMELJIPL_01547 8e-145 cobB2 K Sir2 family
PMELJIPL_01548 2.8e-224 tdcB 4.3.1.19 E Pyridoxal-phosphate dependent enzyme
PMELJIPL_01549 0.0 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
PMELJIPL_01552 2.6e-185 K Psort location Cytoplasmic, score
PMELJIPL_01553 0.0 rafA 3.2.1.22 G Raffinose synthase or seed imbibition protein Sip1
PMELJIPL_01554 1.5e-161 G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01555 6.8e-184 G Binding-protein-dependent transport system inner membrane component
PMELJIPL_01556 1.2e-236 msmE7 G Bacterial extracellular solute-binding protein
PMELJIPL_01557 3.6e-232 nagC GK ROK family
PMELJIPL_01558 0.0 3.2.1.22 G Glycosyl hydrolase family 36 N-terminal domain
PMELJIPL_01559 5.7e-85 tadA 3.5.4.1, 3.5.4.33, 3.8.1.5, 6.3.4.19 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PMELJIPL_01560 0.0 yjcE P Sodium/hydrogen exchanger family
PMELJIPL_01561 3.6e-171 ypfH S Phospholipase/Carboxylesterase
PMELJIPL_01562 7.8e-122 D nuclear chromosome segregation
PMELJIPL_01563 1.2e-21 D nuclear chromosome segregation
PMELJIPL_01564 6.9e-112 dcd 3.5.4.13 F Belongs to the dCTP deaminase family
PMELJIPL_01565 0.0 pacL2 3.6.3.8 P Cation transporter/ATPase, N-terminus
PMELJIPL_01566 2.6e-175 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PMELJIPL_01567 3.6e-127 merA 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PMELJIPL_01568 2e-277 KLT Domain of unknown function (DUF4032)
PMELJIPL_01569 4.3e-211 ugpC E Belongs to the ABC transporter superfamily
PMELJIPL_01570 5.5e-189 U Ion channel
PMELJIPL_01571 0.0 KLT Protein tyrosine kinase
PMELJIPL_01572 2.6e-85 O Thioredoxin
PMELJIPL_01574 1.2e-219 S G5
PMELJIPL_01575 7e-164 ksgA 2.1.1.182, 2.1.1.184 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PMELJIPL_01576 4.1e-178 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
PMELJIPL_01577 1.5e-112 S LytR cell envelope-related transcriptional attenuator
PMELJIPL_01578 1.4e-308 cca 2.7.7.19, 2.7.7.72 J Probable RNA and SrmB- binding site of polymerase A
PMELJIPL_01579 1.7e-171 deoC 3.6.1.13, 3.6.1.17, 3.6.1.55, 3.6.1.61 L Belongs to the Nudix hydrolase family
PMELJIPL_01580 0.0
PMELJIPL_01581 0.0 murJ KLT MviN-like protein
PMELJIPL_01582 1.3e-179 trxB 1.8.1.9, 4.3.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PMELJIPL_01583 6e-231 parB K Belongs to the ParB family
PMELJIPL_01584 8.7e-176 parA D CobQ CobB MinD ParA nucleotide binding domain protein
PMELJIPL_01586 8.8e-136 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
PMELJIPL_01587 3.2e-95 jag S Putative single-stranded nucleic acids-binding domain
PMELJIPL_01588 5.6e-178 yidC U Membrane protein insertase, YidC Oxa1 family
PMELJIPL_01589 5.9e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
PMELJIPL_01590 0.0 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PMELJIPL_01591 2.4e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PMELJIPL_01592 2e-266 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PMELJIPL_01593 5.8e-91 S Protein of unknown function (DUF721)
PMELJIPL_01594 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMELJIPL_01595 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PMELJIPL_01596 6.2e-75 S Transmembrane domain of unknown function (DUF3566)
PMELJIPL_01597 5.2e-217 V VanZ like family
PMELJIPL_01598 4.2e-161 yplQ S Haemolysin-III related
PMELJIPL_01599 5.8e-263 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PMELJIPL_01600 8.7e-227 EGP Major facilitator Superfamily
PMELJIPL_01601 1.1e-119 int L Phage integrase, N-terminal SAM-like domain
PMELJIPL_01602 1e-165 S Protein of unknown function DUF262
PMELJIPL_01603 1.1e-92 dinD S SOS response
PMELJIPL_01604 1.1e-22 K Transcriptional regulator
PMELJIPL_01607 1.5e-52 dnaQ 2.7.7.7 L Exonuclease, DNA polymerase III, epsilon subunit family
PMELJIPL_01608 1.1e-25 S IrrE N-terminal-like domain
PMELJIPL_01609 2.5e-30
PMELJIPL_01610 1.2e-28 K Helix-turn-helix XRE-family like proteins
PMELJIPL_01612 2.5e-11
PMELJIPL_01615 1.5e-42 ssb1 L Single-stranded DNA-binding protein
PMELJIPL_01616 3.7e-23
PMELJIPL_01617 4.1e-26 K Transcriptional regulator
PMELJIPL_01621 9.8e-58 K BRO family, N-terminal domain
PMELJIPL_01622 1.8e-17
PMELJIPL_01624 3.1e-38 A 3'-to-5' exoribonuclease specific for small oligoribonucleotides
PMELJIPL_01626 2.9e-32 J tRNA 5'-leader removal
PMELJIPL_01627 3e-17
PMELJIPL_01629 9.1e-45 V HNH nucleases
PMELJIPL_01630 1.5e-13
PMELJIPL_01631 1.5e-160 S Terminase
PMELJIPL_01632 1.9e-171 S Phage portal protein, SPP1 Gp6-like
PMELJIPL_01633 3.1e-99
PMELJIPL_01635 9.2e-11
PMELJIPL_01636 4.3e-135
PMELJIPL_01638 1.2e-22 S Phage protein Gp19/Gp15/Gp42
PMELJIPL_01639 2e-26
PMELJIPL_01640 1.3e-27
PMELJIPL_01642 1.3e-60
PMELJIPL_01644 1e-23
PMELJIPL_01645 5.7e-104 S phage tail tape measure protein
PMELJIPL_01646 2.1e-109 amyB3 S Fibronectin type 3 domain
PMELJIPL_01647 1.6e-106
PMELJIPL_01650 2.6e-45
PMELJIPL_01651 4.4e-90 ps461 3.5.1.104 M Glycosyl hydrolases family 25
PMELJIPL_01652 5.6e-15

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)