ORF_ID e_value Gene_name EC_number CAZy COGs Description
MKNIKAKF_00001 9.4e-12 XK27_02675 K Acetyltransferase (GNAT) domain
MKNIKAKF_00003 1.5e-109 1.6.5.2 S Flavodoxin-like fold
MKNIKAKF_00004 1e-97 K Bacterial regulatory proteins, tetR family
MKNIKAKF_00005 3.2e-144 hutG 3.5.3.8 E N-formylglutamate amidohydrolase
MKNIKAKF_00006 3.6e-54 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
MKNIKAKF_00007 5.8e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKNIKAKF_00008 5.3e-95 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKNIKAKF_00009 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MKNIKAKF_00010 1.8e-57
MKNIKAKF_00011 1.4e-81 6.3.3.2 S ASCH
MKNIKAKF_00012 1.8e-23
MKNIKAKF_00013 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKNIKAKF_00014 1.9e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKNIKAKF_00015 4.4e-309 dnaK O Heat shock 70 kDa protein
MKNIKAKF_00016 3.4e-98 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKNIKAKF_00017 4.2e-192 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKNIKAKF_00018 5.3e-225 hemN H Involved in the biosynthesis of porphyrin-containing compound
MKNIKAKF_00019 3.1e-178 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MKNIKAKF_00020 4.4e-166 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKNIKAKF_00021 1e-142 terC P Integral membrane protein TerC family
MKNIKAKF_00022 4.6e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKNIKAKF_00023 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKNIKAKF_00024 6.5e-45 ylxQ J ribosomal protein
MKNIKAKF_00025 1.7e-45 ylxR K Protein of unknown function (DUF448)
MKNIKAKF_00026 1.7e-195 nusA K Participates in both transcription termination and antitermination
MKNIKAKF_00027 1.7e-84 rimP J Required for maturation of 30S ribosomal subunits
MKNIKAKF_00028 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNIKAKF_00029 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKNIKAKF_00030 1.4e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MKNIKAKF_00031 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
MKNIKAKF_00032 2.7e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKNIKAKF_00033 1.1e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKNIKAKF_00034 5.9e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MKNIKAKF_00035 1.5e-155 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKNIKAKF_00036 1e-142 rpsB J Belongs to the universal ribosomal protein uS2 family
MKNIKAKF_00037 5.2e-46 yazA L GIY-YIG catalytic domain protein
MKNIKAKF_00038 4.2e-130 yabB 2.1.1.223 L Methyltransferase small domain
MKNIKAKF_00039 2.6e-123 plsC 2.3.1.51 I Acyltransferase
MKNIKAKF_00040 4e-214 yfnA E Amino Acid
MKNIKAKF_00041 6.7e-142 yejC S Protein of unknown function (DUF1003)
MKNIKAKF_00042 0.0 mdlB V ABC transporter
MKNIKAKF_00043 0.0 mdlA V ABC transporter
MKNIKAKF_00044 4.8e-29 yneF S UPF0154 protein
MKNIKAKF_00045 4e-37 ynzC S UPF0291 protein
MKNIKAKF_00046 2.1e-19
MKNIKAKF_00047 2.9e-57 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKNIKAKF_00048 1.1e-144 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MKNIKAKF_00049 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKNIKAKF_00050 2.2e-38 ylqC S Belongs to the UPF0109 family
MKNIKAKF_00051 1e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MKNIKAKF_00052 6.3e-231 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKNIKAKF_00053 3.8e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKNIKAKF_00055 8.8e-53
MKNIKAKF_00056 1.4e-181 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKNIKAKF_00057 0.0 smc D Required for chromosome condensation and partitioning
MKNIKAKF_00058 1.7e-125 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKNIKAKF_00059 0.0 oppA1 E ABC transporter substrate-binding protein
MKNIKAKF_00060 1.5e-137 oppC EP Binding-protein-dependent transport system inner membrane component
MKNIKAKF_00061 9.2e-170 oppB P ABC transporter permease
MKNIKAKF_00062 1.4e-178 oppF P Belongs to the ABC transporter superfamily
MKNIKAKF_00063 5.7e-194 oppD P Belongs to the ABC transporter superfamily
MKNIKAKF_00064 8.9e-37 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNIKAKF_00065 2.3e-187 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKNIKAKF_00066 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKNIKAKF_00067 9.3e-311 yloV S DAK2 domain fusion protein YloV
MKNIKAKF_00068 2.3e-57 asp S Asp23 family, cell envelope-related function
MKNIKAKF_00069 2.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MKNIKAKF_00070 2.1e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
MKNIKAKF_00071 3e-116 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MKNIKAKF_00072 7.6e-174 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKNIKAKF_00073 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MKNIKAKF_00074 9.7e-135 stp 3.1.3.16 T phosphatase
MKNIKAKF_00075 8.9e-256 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKNIKAKF_00076 2.2e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKNIKAKF_00077 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKNIKAKF_00078 2.1e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKNIKAKF_00079 1.3e-35 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKNIKAKF_00080 1.9e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MKNIKAKF_00081 1.6e-91 rssA S Patatin-like phospholipase
MKNIKAKF_00082 1.9e-49
MKNIKAKF_00084 0.0 recN L May be involved in recombinational repair of damaged DNA
MKNIKAKF_00085 2e-74 argR K Regulates arginine biosynthesis genes
MKNIKAKF_00086 1e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MKNIKAKF_00087 4.6e-149 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKNIKAKF_00088 1.6e-32 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNIKAKF_00089 7.7e-199 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKNIKAKF_00090 4.6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKNIKAKF_00091 4.7e-67 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKNIKAKF_00092 2.2e-76 yqhY S Asp23 family, cell envelope-related function
MKNIKAKF_00093 1.1e-101 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKNIKAKF_00095 2.7e-202 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKNIKAKF_00096 1.7e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MKNIKAKF_00097 5.5e-56 ysxB J Cysteine protease Prp
MKNIKAKF_00098 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MKNIKAKF_00099 3.2e-11
MKNIKAKF_00100 1e-16
MKNIKAKF_00102 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MKNIKAKF_00103 5.4e-261 glnA 6.3.1.2 E glutamine synthetase
MKNIKAKF_00104 1e-60 glnR K Transcriptional regulator
MKNIKAKF_00105 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
MKNIKAKF_00106 1.4e-239 ynbB 4.4.1.1 P aluminum resistance
MKNIKAKF_00107 2.9e-173 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKNIKAKF_00108 1.5e-25 WQ51_02665 S Protein of unknown function (DUF3042)
MKNIKAKF_00109 2.6e-73 yqhL P Rhodanese-like protein
MKNIKAKF_00110 5.4e-178 glk 2.7.1.2 G Glucokinase
MKNIKAKF_00111 2.4e-40 yqgQ S Bacterial protein of unknown function (DUF910)
MKNIKAKF_00112 7.3e-121 gluP 3.4.21.105 S Peptidase, S54 family
MKNIKAKF_00113 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MKNIKAKF_00114 0.0 S Bacterial membrane protein YfhO
MKNIKAKF_00115 2.1e-54 yneR S Belongs to the HesB IscA family
MKNIKAKF_00116 6.9e-116 vraR K helix_turn_helix, Lux Regulon
MKNIKAKF_00117 1.4e-179 vraS 2.7.13.3 T Histidine kinase
MKNIKAKF_00118 3.2e-119 yvqF S Cell wall-active antibiotics response 4TMS YvqF
MKNIKAKF_00119 6.9e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKNIKAKF_00120 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
MKNIKAKF_00121 5.2e-204 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKNIKAKF_00122 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNIKAKF_00123 1.3e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKNIKAKF_00124 6.3e-66 yodB K Transcriptional regulator, HxlR family
MKNIKAKF_00125 7.3e-94 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNIKAKF_00126 5.1e-139 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNIKAKF_00127 1.9e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MKNIKAKF_00128 1.9e-173 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNIKAKF_00129 1.5e-289 arlS 2.7.13.3 T Histidine kinase
MKNIKAKF_00130 7.9e-123 K response regulator
MKNIKAKF_00131 3.7e-268 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKNIKAKF_00132 8e-38 yhcX S Psort location Cytoplasmic, score
MKNIKAKF_00133 4.5e-97 yceD S Uncharacterized ACR, COG1399
MKNIKAKF_00134 1.2e-208 ylbM S Belongs to the UPF0348 family
MKNIKAKF_00135 3.2e-138 yccK Q ubiE/COQ5 methyltransferase family
MKNIKAKF_00136 1.9e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKNIKAKF_00137 5.6e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MKNIKAKF_00138 5.7e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKNIKAKF_00139 3.8e-48 yhbY J RNA-binding protein
MKNIKAKF_00140 2.1e-205 yqeH S Ribosome biogenesis GTPase YqeH
MKNIKAKF_00141 2.9e-96 yqeG S HAD phosphatase, family IIIA
MKNIKAKF_00142 1.6e-171 ykcA E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNIKAKF_00143 1.2e-190 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNIKAKF_00144 3.6e-122 mhqD S Dienelactone hydrolase family
MKNIKAKF_00145 1.3e-179 3.5.1.10 C Alcohol dehydrogenase GroES-like domain
MKNIKAKF_00146 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
MKNIKAKF_00147 8.7e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKNIKAKF_00148 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MKNIKAKF_00149 1.5e-77 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKNIKAKF_00150 8.2e-128 S SseB protein N-terminal domain
MKNIKAKF_00151 1.6e-53
MKNIKAKF_00152 2e-103 yrgI 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
MKNIKAKF_00153 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKNIKAKF_00154 1.2e-171 dnaI L Primosomal protein DnaI
MKNIKAKF_00155 1.5e-250 dnaB L replication initiation and membrane attachment
MKNIKAKF_00156 7.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKNIKAKF_00157 2e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKNIKAKF_00158 7.9e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKNIKAKF_00159 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKNIKAKF_00160 4.2e-119 ybhL S Inhibitor of apoptosis-promoting Bax1
MKNIKAKF_00161 2e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MKNIKAKF_00162 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MKNIKAKF_00163 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKNIKAKF_00164 1.5e-55 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MKNIKAKF_00166 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKNIKAKF_00167 1e-147 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MKNIKAKF_00169 1.7e-213 ecsB U ABC transporter
MKNIKAKF_00170 3.1e-133 ecsA V ABC transporter, ATP-binding protein
MKNIKAKF_00171 1e-75 hit FG histidine triad
MKNIKAKF_00172 2.7e-61 yhaH S YtxH-like protein
MKNIKAKF_00173 8.1e-160 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKNIKAKF_00174 4e-181 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNIKAKF_00175 3.9e-54 yheA S Control of competence regulator ComK, YlbF/YmcA
MKNIKAKF_00176 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MKNIKAKF_00177 1.8e-153 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKNIKAKF_00178 5.3e-75 argR K Regulates arginine biosynthesis genes
MKNIKAKF_00179 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MKNIKAKF_00181 1.2e-67
MKNIKAKF_00182 2.1e-22
MKNIKAKF_00183 1.3e-176 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
MKNIKAKF_00184 0.0 glpQ 3.1.4.46 C phosphodiesterase
MKNIKAKF_00185 1.1e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MKNIKAKF_00186 3.2e-68 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKNIKAKF_00187 3.3e-135 yhfI S Metallo-beta-lactamase superfamily
MKNIKAKF_00188 1.1e-92 traP 1.14.99.57, 6.2.1.3 S heme oxygenase (decyclizing) activity
MKNIKAKF_00189 0.0 V ABC transporter (permease)
MKNIKAKF_00190 9.7e-138 bceA V ABC transporter
MKNIKAKF_00191 5.9e-123 K response regulator
MKNIKAKF_00192 5.9e-205 T PhoQ Sensor
MKNIKAKF_00193 1.6e-108 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKNIKAKF_00194 0.0 copB 3.6.3.4 P P-type ATPase
MKNIKAKF_00195 5.1e-75 copR K Copper transport repressor CopY TcrY
MKNIKAKF_00196 3.4e-233 purD 6.3.4.13 F Belongs to the GARS family
MKNIKAKF_00197 1.1e-286 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MKNIKAKF_00198 7.8e-100 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKNIKAKF_00199 1.3e-182 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MKNIKAKF_00200 2.9e-276 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKNIKAKF_00201 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNIKAKF_00202 1.1e-127 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNIKAKF_00203 1.9e-40 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKNIKAKF_00204 5.8e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MKNIKAKF_00205 2.5e-211 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKNIKAKF_00206 3.2e-78 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKNIKAKF_00207 4.7e-103 thiT S Thiamine transporter protein (Thia_YuaJ)
MKNIKAKF_00208 1.1e-256 iolT EGP Major facilitator Superfamily
MKNIKAKF_00209 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKNIKAKF_00210 2.7e-39 ptsH G phosphocarrier protein HPR
MKNIKAKF_00211 2e-28
MKNIKAKF_00212 0.0 clpE O Belongs to the ClpA ClpB family
MKNIKAKF_00213 1.4e-44 XK27_09445 S Domain of unknown function (DUF1827)
MKNIKAKF_00215 6.5e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MKNIKAKF_00216 6.7e-243 hlyX S Transporter associated domain
MKNIKAKF_00217 2.7e-195 yueF S AI-2E family transporter
MKNIKAKF_00218 4e-72 S Acetyltransferase (GNAT) domain
MKNIKAKF_00219 1.2e-94
MKNIKAKF_00220 6.4e-104 ygaC J Belongs to the UPF0374 family
MKNIKAKF_00221 8.7e-142 recX 2.4.1.337 GT4 S Regulatory protein RecX
MKNIKAKF_00222 2.3e-292 frvR K transcriptional antiterminator
MKNIKAKF_00223 2.9e-63
MKNIKAKF_00224 9.8e-250 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNIKAKF_00225 8.2e-79 F Nucleoside 2-deoxyribosyltransferase
MKNIKAKF_00226 1.8e-133 K UTRA
MKNIKAKF_00227 3.5e-290 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKNIKAKF_00228 9.4e-253 celD 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_00229 3e-84
MKNIKAKF_00230 2e-49 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MKNIKAKF_00231 6.9e-50 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_00232 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKNIKAKF_00233 9.9e-219 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MKNIKAKF_00234 1.6e-201 mvaA 1.1.1.34, 1.1.1.88 C Belongs to the HMG-CoA reductase family
MKNIKAKF_00235 4.2e-209 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
MKNIKAKF_00236 1.6e-48
MKNIKAKF_00237 2.6e-160 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MKNIKAKF_00238 5.7e-103 V Restriction endonuclease
MKNIKAKF_00239 5.8e-157 5.1.3.3 G converts alpha-aldose to the beta-anomer
MKNIKAKF_00240 5.2e-212 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKNIKAKF_00241 1e-102 S ECF transporter, substrate-specific component
MKNIKAKF_00243 2.1e-79 yodP 2.3.1.264 K Acetyltransferase GNAT Family
MKNIKAKF_00244 8.1e-84 ydcK S Belongs to the SprT family
MKNIKAKF_00245 1.9e-130 XK27_08845 S ABC transporter, ATP-binding protein
MKNIKAKF_00246 4.2e-140 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MKNIKAKF_00247 3.3e-154 XK27_08835 S ABC transporter
MKNIKAKF_00249 2.6e-71
MKNIKAKF_00250 0.0 pacL 3.6.3.8 P P-type ATPase
MKNIKAKF_00251 9.2e-217 V Beta-lactamase
MKNIKAKF_00252 1.3e-151 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKNIKAKF_00253 1e-196 V Beta-lactamase
MKNIKAKF_00254 7.2e-275 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKNIKAKF_00255 5e-125 gntR1 K UbiC transcription regulator-associated domain protein
MKNIKAKF_00256 2.6e-219 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKNIKAKF_00257 1.1e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKNIKAKF_00258 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
MKNIKAKF_00261 2.4e-158 yjjH S Calcineurin-like phosphoesterase
MKNIKAKF_00262 4.6e-266 dtpT U amino acid peptide transporter
MKNIKAKF_00263 0.0 macB_3 V ABC transporter, ATP-binding protein
MKNIKAKF_00264 3.1e-65
MKNIKAKF_00265 3.4e-76 S function, without similarity to other proteins
MKNIKAKF_00266 1.2e-263 G MFS/sugar transport protein
MKNIKAKF_00267 3.2e-230 alfA 3.2.1.51 GH29 G Alpha-L-fucosidase
MKNIKAKF_00268 1.6e-57
MKNIKAKF_00269 0.0 pckG 4.1.1.32, 4.1.1.49 C Phosphoenolpyruvate carboxykinase
MKNIKAKF_00270 1.4e-17 S Virus attachment protein p12 family
MKNIKAKF_00271 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MKNIKAKF_00272 9.3e-261 pepC 3.4.22.40 E Peptidase C1-like family
MKNIKAKF_00273 3.6e-257 pepC 3.4.22.40 E aminopeptidase
MKNIKAKF_00274 9.5e-70 S Protein of unknown function (DUF805)
MKNIKAKF_00275 2.9e-50 HA62_12640 S GCN5-related N-acetyl-transferase
MKNIKAKF_00276 9.6e-100 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTPase
MKNIKAKF_00277 6.5e-254 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKNIKAKF_00278 1.2e-202 yacL S domain protein
MKNIKAKF_00279 1.7e-216 inlJ M MucBP domain
MKNIKAKF_00280 8e-61 K helix_turn_helix gluconate operon transcriptional repressor
MKNIKAKF_00281 6.9e-176 S Membrane
MKNIKAKF_00282 6.9e-113 yhfC S Putative membrane peptidase family (DUF2324)
MKNIKAKF_00283 9.1e-142 K SIS domain
MKNIKAKF_00284 2.3e-76 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MKNIKAKF_00285 4.3e-183 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
MKNIKAKF_00286 6.2e-274 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKNIKAKF_00288 2.3e-107
MKNIKAKF_00289 1.6e-260 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
MKNIKAKF_00290 1.4e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKNIKAKF_00291 8.5e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKNIKAKF_00292 1.4e-139 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKNIKAKF_00293 2.4e-98 yacP S YacP-like NYN domain
MKNIKAKF_00295 5.7e-189 XK27_00915 C Luciferase-like monooxygenase
MKNIKAKF_00296 7e-93 1.5.1.40 S Rossmann-like domain
MKNIKAKF_00299 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKNIKAKF_00300 1.2e-98 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
MKNIKAKF_00301 1.2e-79 ynhH S NusG domain II
MKNIKAKF_00302 0.0 ndh 1.6.99.3 C NADH dehydrogenase
MKNIKAKF_00303 1.2e-137 cad S FMN_bind
MKNIKAKF_00304 4.4e-197 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKNIKAKF_00305 1.1e-167 menA 2.5.1.74 M UbiA prenyltransferase family
MKNIKAKF_00306 2e-155 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MKNIKAKF_00307 1.6e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKNIKAKF_00308 3.4e-100 nusG K Participates in transcription elongation, termination and antitermination
MKNIKAKF_00309 3.8e-159 S Alpha/beta hydrolase of unknown function (DUF915)
MKNIKAKF_00310 1.4e-77 F Nucleoside 2-deoxyribosyltransferase
MKNIKAKF_00311 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
MKNIKAKF_00312 2e-62 S Domain of unknown function (DUF4430)
MKNIKAKF_00313 3.2e-93 S ECF transporter, substrate-specific component
MKNIKAKF_00314 1.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S Cobalamin adenosyltransferase
MKNIKAKF_00315 1.1e-65 frataxin S Domain of unknown function (DU1801)
MKNIKAKF_00316 7.7e-269 nylA 3.5.1.4 J Belongs to the amidase family
MKNIKAKF_00317 0.0 mgtA 3.6.3.2, 3.6.3.6 P COG0474 Cation transport ATPase
MKNIKAKF_00318 8.2e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKNIKAKF_00319 1.3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKNIKAKF_00320 2.5e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MKNIKAKF_00321 1.9e-217 yceI G Sugar (and other) transporter
MKNIKAKF_00322 3.1e-66
MKNIKAKF_00323 1.6e-154 K acetyltransferase
MKNIKAKF_00324 5e-221 mdtG EGP Major facilitator Superfamily
MKNIKAKF_00325 6.5e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKNIKAKF_00326 1.1e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKNIKAKF_00327 1.3e-104 L Belongs to the 'phage' integrase family
MKNIKAKF_00328 7.8e-50 S Domain of unknown function (DUF4352)
MKNIKAKF_00329 4.8e-73
MKNIKAKF_00330 1.1e-74 E Zn peptidase
MKNIKAKF_00331 4.2e-53 3.4.21.88 K Helix-turn-helix domain
MKNIKAKF_00332 1.6e-07 K Helix-turn-helix
MKNIKAKF_00336 1.3e-15
MKNIKAKF_00339 7.5e-155 recT L RecT family
MKNIKAKF_00340 8.5e-148 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
MKNIKAKF_00341 3.1e-52 L Domain of unknown function (DUF4373)
MKNIKAKF_00342 3.5e-127 dnaC 3.4.21.53 L IstB-like ATP binding protein
MKNIKAKF_00344 1.6e-36
MKNIKAKF_00345 3e-65 S magnesium ion binding
MKNIKAKF_00346 9.8e-37 S DNA N-6-adenine-methyltransferase (Dam)
MKNIKAKF_00347 6.9e-14
MKNIKAKF_00352 5.4e-22
MKNIKAKF_00356 2.9e-78
MKNIKAKF_00357 7.9e-09 S Super-infection exclusion protein B
MKNIKAKF_00359 2.2e-218 S GcrA cell cycle regulator
MKNIKAKF_00362 5.1e-64 ps333 L Terminase small subunit
MKNIKAKF_00363 6.5e-179 S Phage terminase large subunit
MKNIKAKF_00364 4.2e-177 S Phage portal protein, SPP1 Gp6-like
MKNIKAKF_00365 2.6e-60 S Phage Mu protein F like protein
MKNIKAKF_00367 1.9e-18 S Domain of unknown function (DUF4355)
MKNIKAKF_00368 3.3e-108
MKNIKAKF_00369 7.9e-144
MKNIKAKF_00370 1.7e-55 S Phage gp6-like head-tail connector protein
MKNIKAKF_00371 3.8e-49
MKNIKAKF_00372 3.7e-55 S Bacteriophage HK97-gp10, putative tail-component
MKNIKAKF_00373 7.8e-70 S Protein of unknown function (DUF3168)
MKNIKAKF_00374 1.6e-95 S Phage tail tube protein
MKNIKAKF_00375 8.1e-49 S Phage tail assembly chaperone protein, TAC
MKNIKAKF_00376 3.1e-54
MKNIKAKF_00377 2e-279 S phage tail tape measure protein
MKNIKAKF_00378 2.4e-286 S Phage tail protein
MKNIKAKF_00379 0.0 S cellulase activity
MKNIKAKF_00380 1.2e-26
MKNIKAKF_00382 1.1e-46
MKNIKAKF_00383 1.9e-42 hol S Bacteriophage holin
MKNIKAKF_00384 6.9e-85 M Bacteriophage peptidoglycan hydrolase
MKNIKAKF_00385 1.6e-155 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKNIKAKF_00386 0.0 prtS 3.4.21.110, 3.4.21.96 O Belongs to the peptidase S8 family
MKNIKAKF_00387 2.2e-176 ccpB 5.1.1.1 K lacI family
MKNIKAKF_00388 1.8e-45
MKNIKAKF_00389 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKNIKAKF_00390 5.3e-107 rsmC 2.1.1.172 J Methyltransferase
MKNIKAKF_00391 5.6e-50
MKNIKAKF_00392 2.5e-89 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKNIKAKF_00393 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKNIKAKF_00394 8.4e-32 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKNIKAKF_00395 4.8e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKNIKAKF_00396 5.8e-34 S Protein of unknown function (DUF2508)
MKNIKAKF_00397 5.1e-116 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKNIKAKF_00398 4.6e-52 yaaQ S Cyclic-di-AMP receptor
MKNIKAKF_00399 5.8e-172 holB 2.7.7.7 L DNA polymerase III
MKNIKAKF_00400 2.2e-57 yabA L Involved in initiation control of chromosome replication
MKNIKAKF_00401 2.2e-143 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKNIKAKF_00402 8.7e-144 fat 3.1.2.21 I Acyl-ACP thioesterase
MKNIKAKF_00403 2e-180 ansA 3.5.1.1 EJ Asparaginase
MKNIKAKF_00404 3.3e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
MKNIKAKF_00405 4.6e-74
MKNIKAKF_00406 5.3e-130 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MKNIKAKF_00407 3.6e-99 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MKNIKAKF_00408 4.2e-189 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKNIKAKF_00409 3.9e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_00410 0.0 uup S ABC transporter, ATP-binding protein
MKNIKAKF_00411 7.2e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKNIKAKF_00412 2.7e-61 ytrA K helix_turn_helix gluconate operon transcriptional repressor
MKNIKAKF_00413 2.6e-158 ytrB V ABC transporter
MKNIKAKF_00414 1.8e-184
MKNIKAKF_00415 2.4e-195 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKNIKAKF_00416 1.9e-110 S CAAX protease self-immunity
MKNIKAKF_00417 6.7e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKNIKAKF_00418 1e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKNIKAKF_00419 2.4e-56 S Domain of unknown function (DUF1827)
MKNIKAKF_00420 0.0 ydaO E amino acid
MKNIKAKF_00421 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKNIKAKF_00422 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKNIKAKF_00423 1.1e-98 maf D nucleoside-triphosphate diphosphatase activity
MKNIKAKF_00424 2.8e-61 S Domain of unknown function (DUF4811)
MKNIKAKF_00425 1e-257 lmrB EGP Major facilitator Superfamily
MKNIKAKF_00426 5.3e-259 yhdP S Transporter associated domain
MKNIKAKF_00427 1.2e-132 S Uncharacterized protein conserved in bacteria (DUF2263)
MKNIKAKF_00428 6.2e-119 yfeJ 6.3.5.2 F glutamine amidotransferase
MKNIKAKF_00429 3.4e-90 T Sh3 type 3 domain protein
MKNIKAKF_00430 5.8e-100 Q methyltransferase
MKNIKAKF_00432 4.9e-114 GM NmrA-like family
MKNIKAKF_00433 8.1e-196 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MKNIKAKF_00434 3.6e-82 C Flavodoxin
MKNIKAKF_00435 2.7e-44 fer C 4Fe-4S single cluster domain of Ferredoxin I
MKNIKAKF_00436 5.3e-181 ypbB 5.1.3.1 S Helix-turn-helix domain
MKNIKAKF_00437 3.2e-264 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MKNIKAKF_00438 6.1e-66 M Lysin motif
MKNIKAKF_00439 2e-115 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MKNIKAKF_00440 2.1e-225 rpsA 1.17.7.4 J Ribosomal protein S1
MKNIKAKF_00441 1e-243 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MKNIKAKF_00442 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKNIKAKF_00443 2.3e-237 S Tetratricopeptide repeat protein
MKNIKAKF_00444 2.6e-147 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNIKAKF_00445 3.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKNIKAKF_00446 1.3e-84
MKNIKAKF_00447 0.0 yfmR S ABC transporter, ATP-binding protein
MKNIKAKF_00448 2.1e-190 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKNIKAKF_00449 2.2e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKNIKAKF_00450 2.1e-114 hly S protein, hemolysin III
MKNIKAKF_00451 1.5e-145 DegV S EDD domain protein, DegV family
MKNIKAKF_00452 4.5e-152 ypmR E GDSL-like Lipase/Acylhydrolase
MKNIKAKF_00453 1.2e-112 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MKNIKAKF_00454 3.5e-91 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKNIKAKF_00455 1.1e-39 yozE S Belongs to the UPF0346 family
MKNIKAKF_00456 9.3e-240 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MKNIKAKF_00457 4.5e-49 K Helix-turn-helix domain
MKNIKAKF_00458 1.9e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKNIKAKF_00459 1.1e-138 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKNIKAKF_00460 1.9e-144 dprA LU DNA protecting protein DprA
MKNIKAKF_00461 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKNIKAKF_00462 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKNIKAKF_00463 2.1e-168 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MKNIKAKF_00464 7.2e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKNIKAKF_00465 1.2e-258 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKNIKAKF_00466 1.8e-172 lacX 5.1.3.3 G Aldose 1-epimerase
MKNIKAKF_00467 1.7e-108 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKNIKAKF_00468 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNIKAKF_00469 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKNIKAKF_00470 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MKNIKAKF_00471 5.6e-171 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKNIKAKF_00472 3.4e-180 K LysR substrate binding domain
MKNIKAKF_00473 1.8e-170 ppaC 3.6.1.1 C inorganic pyrophosphatase
MKNIKAKF_00474 1.1e-209 xerS L Belongs to the 'phage' integrase family
MKNIKAKF_00475 8.1e-39
MKNIKAKF_00476 0.0 ysaB V FtsX-like permease family
MKNIKAKF_00477 6.3e-137 XK27_05695 V ABC transporter, ATP-binding protein
MKNIKAKF_00478 2.3e-173 T PhoQ Sensor
MKNIKAKF_00479 1.4e-122 T Transcriptional regulatory protein, C terminal
MKNIKAKF_00480 6.8e-190 EGP Transmembrane secretion effector
MKNIKAKF_00481 5.3e-47 msi198 K Acetyltransferase (GNAT) domain
MKNIKAKF_00482 2.4e-62 K Acetyltransferase (GNAT) domain
MKNIKAKF_00483 3.7e-111 nfnB 1.5.1.34 C Nitroreductase family
MKNIKAKF_00484 1e-201 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKNIKAKF_00485 1.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MKNIKAKF_00486 5.6e-58 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MKNIKAKF_00487 2.3e-131 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKNIKAKF_00488 2.8e-123 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKNIKAKF_00489 2e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKNIKAKF_00490 7e-104 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MKNIKAKF_00491 2.8e-230 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKNIKAKF_00492 1.9e-110 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKNIKAKF_00493 1.4e-217 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKNIKAKF_00494 2e-205 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKNIKAKF_00495 4.5e-100 3.6.1.13 L Belongs to the Nudix hydrolase family
MKNIKAKF_00496 5.9e-160 degV S EDD domain protein, DegV family
MKNIKAKF_00497 0.0 FbpA K Fibronectin-binding protein
MKNIKAKF_00498 1.5e-49 S MazG-like family
MKNIKAKF_00499 3.4e-195 pfoS S Phosphotransferase system, EIIC
MKNIKAKF_00500 2.4e-178 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKNIKAKF_00501 1.9e-205 bfmBB 2.3.1.168, 2.3.1.61 C 2-oxoacid dehydrogenases acyltransferase (catalytic domain)
MKNIKAKF_00502 3.7e-182 bfmBAB 1.2.4.1, 1.2.4.4 C Transketolase, pyrimidine binding domain
MKNIKAKF_00503 6.6e-187 bfmBAA 1.2.4.4 C Dehydrogenase E1 component
MKNIKAKF_00504 1.4e-259 lpdA 1.8.1.4 C 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain
MKNIKAKF_00505 2.4e-201 buk 2.7.2.7 C Acetokinase family
MKNIKAKF_00506 5.1e-148 pta 2.3.1.19, 2.3.1.8 C Phosphate acetyl/butaryl transferase
MKNIKAKF_00507 8.1e-114 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKNIKAKF_00508 1.4e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKNIKAKF_00509 6.9e-156 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKNIKAKF_00510 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MKNIKAKF_00511 1.5e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKNIKAKF_00512 2.8e-235 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKNIKAKF_00513 1.6e-179 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MKNIKAKF_00514 5.9e-236 pyrP F Permease
MKNIKAKF_00515 1.7e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKNIKAKF_00516 5e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKNIKAKF_00517 2.1e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKNIKAKF_00518 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MKNIKAKF_00519 1.3e-45 S Family of unknown function (DUF5322)
MKNIKAKF_00520 6.5e-69 rnhA 3.1.26.4 L Ribonuclease HI
MKNIKAKF_00521 1.9e-109 XK27_02070 S Nitroreductase family
MKNIKAKF_00522 2.6e-280 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKNIKAKF_00523 1.4e-48
MKNIKAKF_00524 9.3e-275 S Mga helix-turn-helix domain
MKNIKAKF_00525 2e-38 nrdH O Glutaredoxin
MKNIKAKF_00526 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNIKAKF_00527 2.4e-189 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKNIKAKF_00528 7.1e-161 K Transcriptional regulator
MKNIKAKF_00529 0.0 pepO 3.4.24.71 O Peptidase family M13
MKNIKAKF_00530 9.6e-194 lplA 6.3.1.20 H Lipoate-protein ligase
MKNIKAKF_00531 1.9e-33
MKNIKAKF_00532 1e-173 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MKNIKAKF_00533 8.2e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MKNIKAKF_00534 2.3e-66 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKNIKAKF_00535 1.3e-107 ypsA S Belongs to the UPF0398 family
MKNIKAKF_00536 5.1e-121 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKNIKAKF_00537 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MKNIKAKF_00538 4.4e-85 comEB 3.5.4.12 F ComE operon protein 2
MKNIKAKF_00539 3e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKNIKAKF_00540 6.7e-113 dnaD L DnaD domain protein
MKNIKAKF_00541 3.2e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MKNIKAKF_00542 2.2e-218 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MKNIKAKF_00543 7.1e-86 ypmB S Protein conserved in bacteria
MKNIKAKF_00544 1.4e-11 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MKNIKAKF_00545 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MKNIKAKF_00546 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MKNIKAKF_00547 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MKNIKAKF_00548 1.4e-167 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MKNIKAKF_00549 1.3e-179 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MKNIKAKF_00550 1.1e-192 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKNIKAKF_00551 2.6e-263 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
MKNIKAKF_00552 9.4e-175
MKNIKAKF_00553 1.1e-141
MKNIKAKF_00554 8.2e-60 yitW S Iron-sulfur cluster assembly protein
MKNIKAKF_00555 3.5e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MKNIKAKF_00556 6e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKNIKAKF_00557 3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
MKNIKAKF_00558 3.4e-188 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKNIKAKF_00559 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKNIKAKF_00560 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MKNIKAKF_00561 2e-171 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MKNIKAKF_00562 4.2e-89 sip L Phage integrase family
MKNIKAKF_00563 1e-90 sip L Phage integrase family
MKNIKAKF_00565 2.5e-47
MKNIKAKF_00566 7.1e-217 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MKNIKAKF_00567 8e-177 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNIKAKF_00568 2.5e-173 pfoS S Phosphotransferase system, EIIC
MKNIKAKF_00569 2.3e-39
MKNIKAKF_00570 1.1e-166 yqiK S SPFH domain / Band 7 family
MKNIKAKF_00571 1.1e-250 yclM 2.7.2.4 E Belongs to the aspartokinase family
MKNIKAKF_00572 6.4e-229 hom 1.1.1.3 E homoserine dehydrogenase
MKNIKAKF_00573 3.2e-286 thrC 4.2.3.1 E Threonine synthase
MKNIKAKF_00574 2.4e-130 thrB 2.7.1.39, 4.2.3.1 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKNIKAKF_00576 1e-251 yxbA 6.3.1.12 S ATP-grasp enzyme
MKNIKAKF_00577 1.8e-67 usp1 T Universal stress protein family
MKNIKAKF_00578 9.2e-138 sfsA S Belongs to the SfsA family
MKNIKAKF_00579 4.5e-222 gbuA 3.6.3.32 E glycine betaine
MKNIKAKF_00580 2e-131 proW E glycine betaine
MKNIKAKF_00581 4e-167 gbuC E glycine betaine
MKNIKAKF_00582 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKNIKAKF_00583 6e-174 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MKNIKAKF_00584 7.6e-65 gtcA S Teichoic acid glycosylation protein
MKNIKAKF_00586 1.3e-128 srtA 3.4.22.70 M Sortase family
MKNIKAKF_00587 1.2e-186 K AI-2E family transporter
MKNIKAKF_00588 4.4e-200 pbpX1 V Beta-lactamase
MKNIKAKF_00589 1.8e-118 S zinc-ribbon domain
MKNIKAKF_00590 3.8e-20
MKNIKAKF_00591 3.9e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKNIKAKF_00592 3.8e-84 F NUDIX domain
MKNIKAKF_00593 0.0 lmrA 3.6.3.44 V ABC transporter
MKNIKAKF_00594 2.4e-104 rmaB K Transcriptional regulator, MarR family
MKNIKAKF_00595 5.3e-198
MKNIKAKF_00596 1.3e-110 S Putative esterase
MKNIKAKF_00597 1.3e-12 S response to antibiotic
MKNIKAKF_00598 9.1e-66 K MarR family
MKNIKAKF_00599 1.4e-47 S Uncharacterized protein conserved in bacteria (DUF2316)
MKNIKAKF_00600 2.3e-226 bdhA C Iron-containing alcohol dehydrogenase
MKNIKAKF_00601 1e-192 bioH 2.1.1.197, 3.1.1.85, 3.7.1.13, 3.7.1.9, 4.2.99.20 E Alpha/beta hydrolase family
MKNIKAKF_00602 3.1e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MKNIKAKF_00603 6.2e-76 marR K Winged helix DNA-binding domain
MKNIKAKF_00604 5.9e-177 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKNIKAKF_00605 1.2e-33 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKNIKAKF_00606 8.2e-174 fabK 1.3.1.9 S Nitronate monooxygenase
MKNIKAKF_00607 4.7e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MKNIKAKF_00608 4.7e-126 IQ reductase
MKNIKAKF_00609 1.2e-222 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKNIKAKF_00610 5.1e-62 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKNIKAKF_00611 8.7e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKNIKAKF_00612 9.1e-256 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MKNIKAKF_00613 2e-149 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKNIKAKF_00614 2.2e-142 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MKNIKAKF_00615 8.5e-234 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MKNIKAKF_00616 7.1e-164 azoB GM NmrA-like family
MKNIKAKF_00617 6.3e-303 scrB 3.2.1.26 GH32 G invertase
MKNIKAKF_00618 3.2e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MKNIKAKF_00619 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MKNIKAKF_00620 0.0 scrA 2.7.1.211 G phosphotransferase system
MKNIKAKF_00621 2.4e-212 ykiI
MKNIKAKF_00622 7.2e-72 S Putative inner membrane protein (DUF1819)
MKNIKAKF_00623 5.9e-95 S Domain of unknown function (DUF1788)
MKNIKAKF_00624 0.0 FbpA 3.1.21.3, 3.2.1.170 GH38 K RNA-binding protein homologous to eukaryotic snRNP
MKNIKAKF_00625 0.0 2.1.1.72 V Eco57I restriction-modification methylase
MKNIKAKF_00626 2.2e-175 L Belongs to the 'phage' integrase family
MKNIKAKF_00627 4.5e-281 2.1.1.72 V Eco57I restriction-modification methylase
MKNIKAKF_00628 0.0 S PglZ domain
MKNIKAKF_00629 0.0 3.4.21.53 O Putative ATP-dependent Lon protease
MKNIKAKF_00630 3.2e-139
MKNIKAKF_00631 4.3e-104 apc3 3.5.2.9 EQ Hydantoinase/oxoprolinase N-terminal region
MKNIKAKF_00632 3e-145 frlD 2.7.1.218 G pfkB family carbohydrate kinase
MKNIKAKF_00633 2.4e-59 S WxL domain surface cell wall-binding
MKNIKAKF_00634 1.4e-80
MKNIKAKF_00635 0.0 VPA1266 3.1.11.5 L Helix-hairpin-helix containing domain
MKNIKAKF_00636 3.2e-130 XK27_05520 S Uncharacterized protein conserved in bacteria (DUF2087)
MKNIKAKF_00637 7.7e-132 S Belongs to the UPF0246 family
MKNIKAKF_00638 0.0 rafA 3.2.1.22 G alpha-galactosidase
MKNIKAKF_00640 6.6e-265 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_00641 4.8e-07
MKNIKAKF_00642 4.3e-68 S Domain of unknown function (DUF3284)
MKNIKAKF_00643 7.2e-211 S Bacterial protein of unknown function (DUF871)
MKNIKAKF_00644 5.1e-51 chbA 2.7.1.196, 2.7.1.205 G Phosphotransferase system cellobiose-specific component IIA
MKNIKAKF_00645 4.5e-84
MKNIKAKF_00646 1.2e-148 lutA C Cysteine-rich domain
MKNIKAKF_00647 1.7e-287 lutB C 4Fe-4S dicluster domain
MKNIKAKF_00648 7.3e-132 yrjD S LUD domain
MKNIKAKF_00649 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKNIKAKF_00650 9.9e-253 EGP Major facilitator Superfamily
MKNIKAKF_00651 5.9e-302 oppA E ABC transporter, substratebinding protein
MKNIKAKF_00652 8e-163 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNIKAKF_00653 2.5e-178 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNIKAKF_00654 1.1e-197 oppD P Belongs to the ABC transporter superfamily
MKNIKAKF_00655 1.3e-179 oppF P Belongs to the ABC transporter superfamily
MKNIKAKF_00656 1.7e-116 gpm5 3.1.3.3, 5.4.2.11 G Phosphoglycerate mutase family
MKNIKAKF_00657 7.5e-47 K sequence-specific DNA binding
MKNIKAKF_00658 3.7e-37 XK27_01315 S Protein of unknown function (DUF2829)
MKNIKAKF_00659 1.3e-125 IQ Enoyl-(Acyl carrier protein) reductase
MKNIKAKF_00660 1.4e-81 ccl S QueT transporter
MKNIKAKF_00662 2.8e-131 E lipolytic protein G-D-S-L family
MKNIKAKF_00663 4.6e-134 epsB M biosynthesis protein
MKNIKAKF_00664 1e-115 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MKNIKAKF_00665 2.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKNIKAKF_00666 1.4e-164 S Tetratricopeptide repeat
MKNIKAKF_00667 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNIKAKF_00668 1.8e-50
MKNIKAKF_00669 5.4e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKNIKAKF_00671 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MKNIKAKF_00672 1e-169 holA 2.7.7.7 L DNA polymerase III delta subunit
MKNIKAKF_00673 0.0 comEC S Competence protein ComEC
MKNIKAKF_00674 1.1e-111 comEA L Competence protein ComEA
MKNIKAKF_00675 1.4e-181 ylbL T Belongs to the peptidase S16 family
MKNIKAKF_00676 1.5e-86 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKNIKAKF_00677 5.9e-100 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MKNIKAKF_00678 2.5e-62 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MKNIKAKF_00679 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKNIKAKF_00680 2.2e-210 ftsW D Belongs to the SEDS family
MKNIKAKF_00681 0.0 typA T GTP-binding protein TypA
MKNIKAKF_00682 1.3e-145 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MKNIKAKF_00683 2.4e-46 yktA S Belongs to the UPF0223 family
MKNIKAKF_00684 1.1e-156 1.1.1.27 C L-malate dehydrogenase activity
MKNIKAKF_00685 2.4e-259 lpdA 1.8.1.4 C Dehydrogenase
MKNIKAKF_00686 1.2e-265 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKNIKAKF_00687 1.4e-181 pdhB 1.2.4.1, 1.2.4.4 C Transketolase, C-terminal domain protein
MKNIKAKF_00688 2.5e-211 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MKNIKAKF_00689 5.2e-89 S E1-E2 ATPase
MKNIKAKF_00690 2.9e-99 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKNIKAKF_00691 1.3e-45
MKNIKAKF_00692 9.5e-69
MKNIKAKF_00693 2.9e-31 ykzG S Belongs to the UPF0356 family
MKNIKAKF_00694 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKNIKAKF_00695 6.1e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MKNIKAKF_00696 1.4e-244 els S Sterol carrier protein domain
MKNIKAKF_00697 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKNIKAKF_00698 5.3e-116 S Repeat protein
MKNIKAKF_00699 9.9e-123 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MKNIKAKF_00700 1.5e-245 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKNIKAKF_00701 0.0 uvrA2 L ABC transporter
MKNIKAKF_00702 8.3e-57 XK27_04120 S Putative amino acid metabolism
MKNIKAKF_00703 1.3e-218 iscS 2.8.1.7 E Aminotransferase class V
MKNIKAKF_00704 4.8e-123 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKNIKAKF_00705 4.3e-29
MKNIKAKF_00706 1.4e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MKNIKAKF_00707 2e-115 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
MKNIKAKF_00708 6.7e-210 yaaN P Toxic anion resistance protein (TelA)
MKNIKAKF_00709 2.4e-262 ydiC1 EGP Major facilitator Superfamily
MKNIKAKF_00710 6.7e-154 pstS P Phosphate
MKNIKAKF_00711 6.9e-36 cspA K Cold shock protein
MKNIKAKF_00712 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKNIKAKF_00713 5.7e-85 divIVA D DivIVA protein
MKNIKAKF_00714 5.7e-146 ylmH S S4 domain protein
MKNIKAKF_00715 2.4e-44 yggT S integral membrane protein
MKNIKAKF_00716 8.7e-78 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKNIKAKF_00717 3.1e-226 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKNIKAKF_00718 2.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKNIKAKF_00719 5.7e-155 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKNIKAKF_00720 2.5e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKNIKAKF_00721 6e-263 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKNIKAKF_00722 7.5e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKNIKAKF_00723 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MKNIKAKF_00724 3.1e-49 ftsL D cell division protein FtsL
MKNIKAKF_00725 2.4e-170 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKNIKAKF_00726 9.8e-79 mraZ K Belongs to the MraZ family
MKNIKAKF_00727 4.2e-45
MKNIKAKF_00728 3.1e-270 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKNIKAKF_00729 1.2e-151 aatB ET ABC transporter substrate-binding protein
MKNIKAKF_00730 1.5e-112 glnQ 3.6.3.21 E ABC transporter
MKNIKAKF_00731 1.2e-109 artQ P ABC transporter permease
MKNIKAKF_00732 2.6e-141 minD D Belongs to the ParA family
MKNIKAKF_00733 2.2e-114 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKNIKAKF_00734 2.3e-85 mreD M rod shape-determining protein MreD
MKNIKAKF_00735 2.1e-149 mreC M Involved in formation and maintenance of cell shape
MKNIKAKF_00736 1e-179 mreB D cell shape determining protein MreB
MKNIKAKF_00737 2e-118 radC L DNA repair protein
MKNIKAKF_00738 1.1e-113 S Haloacid dehalogenase-like hydrolase
MKNIKAKF_00739 2.3e-240 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MKNIKAKF_00740 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKNIKAKF_00741 6.3e-114 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKNIKAKF_00742 1.1e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKNIKAKF_00743 8.1e-214 iscS2 2.8.1.7 E Aminotransferase class V
MKNIKAKF_00744 2.5e-271 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKNIKAKF_00745 5.1e-84 ytsP 1.8.4.14 T GAF domain-containing protein
MKNIKAKF_00746 6.1e-111 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKNIKAKF_00747 2.4e-69 K Cro/C1-type HTH DNA-binding domain
MKNIKAKF_00748 0.0 yhgF K Tex-like protein N-terminal domain protein
MKNIKAKF_00749 4.9e-11
MKNIKAKF_00750 3e-129 S Protein of unknown function C-terminus (DUF2399)
MKNIKAKF_00751 0.0 D Putative exonuclease SbcCD, C subunit
MKNIKAKF_00752 2.3e-139
MKNIKAKF_00753 8.5e-231
MKNIKAKF_00754 4.8e-46 S Protein of unknown function (DUF2568)
MKNIKAKF_00755 1e-66 K helix_turn_helix, mercury resistance
MKNIKAKF_00756 1.4e-208
MKNIKAKF_00757 4.4e-158 yvfR V ABC transporter
MKNIKAKF_00758 6.5e-134 yvfS V ABC-2 type transporter
MKNIKAKF_00759 9.6e-203 desK 2.7.13.3 T Histidine kinase
MKNIKAKF_00760 1.2e-103 desR K helix_turn_helix, Lux Regulon
MKNIKAKF_00761 6.3e-154 S Uncharacterised protein, DegV family COG1307
MKNIKAKF_00762 7.3e-291 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MKNIKAKF_00763 3.5e-188 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKNIKAKF_00764 5e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKNIKAKF_00765 3e-162 S WxL domain surface cell wall-binding
MKNIKAKF_00766 5e-185 S Bacterial protein of unknown function (DUF916)
MKNIKAKF_00767 1e-156 S Protein of unknown function C-terminal (DUF3324)
MKNIKAKF_00768 0.0 S Leucine-rich repeat (LRR) protein
MKNIKAKF_00769 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKNIKAKF_00770 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MKNIKAKF_00771 3e-240 tilS 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKNIKAKF_00772 9.3e-70 yabR J RNA binding
MKNIKAKF_00773 1.1e-66 divIC D cell cycle
MKNIKAKF_00774 2.7e-39 yabO J S4 domain protein
MKNIKAKF_00775 9.5e-281 yabM S Polysaccharide biosynthesis protein
MKNIKAKF_00776 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKNIKAKF_00777 1.1e-101 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKNIKAKF_00778 4.1e-181 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKNIKAKF_00779 1.5e-261 S Putative peptidoglycan binding domain
MKNIKAKF_00780 2.3e-119 S (CBS) domain
MKNIKAKF_00781 1.8e-99 yciB M ErfK YbiS YcfS YnhG
MKNIKAKF_00783 3e-119 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MKNIKAKF_00784 9.5e-132 gltD 1.4.1.13, 1.4.1.14 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MKNIKAKF_00785 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
MKNIKAKF_00786 3.3e-68 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1, 2.1.1.21 E GXGXG motif
MKNIKAKF_00787 1.1e-84 S QueT transporter
MKNIKAKF_00788 5.6e-62 ndoA L Toxic component of a toxin-antitoxin (TA) module
MKNIKAKF_00789 5.2e-32
MKNIKAKF_00790 9.1e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKNIKAKF_00791 8.5e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKNIKAKF_00792 7e-265 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKNIKAKF_00794 8.7e-262 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKNIKAKF_00795 1.1e-144
MKNIKAKF_00796 9.6e-123 S Tetratricopeptide repeat
MKNIKAKF_00797 4.1e-124
MKNIKAKF_00798 1.2e-65
MKNIKAKF_00799 2.5e-42 rpmE2 J Ribosomal protein L31
MKNIKAKF_00800 1.6e-235 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKNIKAKF_00801 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKNIKAKF_00802 1.3e-157 S Protein of unknown function (DUF1211)
MKNIKAKF_00803 1.7e-53 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKNIKAKF_00804 1e-78 ywiB S Domain of unknown function (DUF1934)
MKNIKAKF_00805 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MKNIKAKF_00806 7.9e-268 ywfO S HD domain protein
MKNIKAKF_00807 2.4e-80 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L NUDIX domain
MKNIKAKF_00808 1.8e-179 S DUF218 domain
MKNIKAKF_00809 2.1e-53 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKNIKAKF_00810 7.2e-209 Q Imidazolonepropionase and related amidohydrolases
MKNIKAKF_00811 1.7e-233 dapE 3.5.1.18 E Peptidase dimerisation domain
MKNIKAKF_00812 9.6e-193 E glutamate:sodium symporter activity
MKNIKAKF_00813 2.6e-55 nudA S ASCH
MKNIKAKF_00814 1.3e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNIKAKF_00815 6.5e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKNIKAKF_00816 5.4e-220 ysaA V RDD family
MKNIKAKF_00817 1e-151 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MKNIKAKF_00818 7.7e-120 ybbL S ABC transporter, ATP-binding protein
MKNIKAKF_00819 9e-120 ybbM S Uncharacterised protein family (UPF0014)
MKNIKAKF_00820 1.3e-159 czcD P cation diffusion facilitator family transporter
MKNIKAKF_00821 6.7e-181 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKNIKAKF_00822 1.1e-37 veg S Biofilm formation stimulator VEG
MKNIKAKF_00823 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKNIKAKF_00824 7.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKNIKAKF_00825 1.8e-147 tatD L hydrolase, TatD family
MKNIKAKF_00826 5.8e-80 manR 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MKNIKAKF_00827 5.6e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MKNIKAKF_00828 2.4e-172 yqhA G Aldose 1-epimerase
MKNIKAKF_00829 4.7e-123 T LytTr DNA-binding domain
MKNIKAKF_00830 3.6e-139 2.7.13.3 T GHKL domain
MKNIKAKF_00831 0.0 V ABC transporter
MKNIKAKF_00832 0.0 V ABC transporter
MKNIKAKF_00833 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKNIKAKF_00834 4.3e-174 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MKNIKAKF_00835 7.3e-152 yunF F Protein of unknown function DUF72
MKNIKAKF_00836 1.2e-90 3.6.1.55 F NUDIX domain
MKNIKAKF_00837 6e-171 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MKNIKAKF_00838 1.6e-106 yiiE S Protein of unknown function (DUF1211)
MKNIKAKF_00839 2.4e-127 cobB K Sir2 family
MKNIKAKF_00840 1.4e-16
MKNIKAKF_00841 6.1e-171
MKNIKAKF_00842 9.4e-97 yxkA S Phosphatidylethanolamine-binding protein
MKNIKAKF_00843 1.6e-18
MKNIKAKF_00844 1.1e-149 ypuA S Protein of unknown function (DUF1002)
MKNIKAKF_00845 2.7e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MKNIKAKF_00846 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MKNIKAKF_00847 2.1e-285 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MKNIKAKF_00848 2.9e-176 S Aldo keto reductase
MKNIKAKF_00849 1.4e-153 Q Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)
MKNIKAKF_00850 8.1e-93 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MKNIKAKF_00851 6.3e-241 dinF V MatE
MKNIKAKF_00852 7.3e-110 S TPM domain
MKNIKAKF_00853 1e-102 lemA S LemA family
MKNIKAKF_00854 1.6e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKNIKAKF_00855 1.5e-50 V efflux transmembrane transporter activity
MKNIKAKF_00856 1.6e-142 V efflux transmembrane transporter activity
MKNIKAKF_00857 1.4e-27 V ATPases associated with a variety of cellular activities
MKNIKAKF_00858 3.2e-55 yphJ 4.1.1.44 S decarboxylase
MKNIKAKF_00859 1.8e-77 yphH S Cupin domain
MKNIKAKF_00860 4.8e-157 K Transcriptional regulator
MKNIKAKF_00861 1.5e-98 S ABC-2 family transporter protein
MKNIKAKF_00862 7.5e-169 bcrA V AAA domain, putative AbiEii toxin, Type IV TA system
MKNIKAKF_00863 4.9e-117 T Transcriptional regulatory protein, C terminal
MKNIKAKF_00864 1.9e-156 T GHKL domain
MKNIKAKF_00865 0.0 oppA E ABC transporter, substratebinding protein
MKNIKAKF_00866 1.2e-157 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MKNIKAKF_00867 5.2e-133 dck 2.7.1.74 F deoxynucleoside kinase
MKNIKAKF_00868 1.6e-137 pnuC H nicotinamide mononucleotide transporter
MKNIKAKF_00869 2.1e-171 IQ NAD dependent epimerase/dehydratase family
MKNIKAKF_00870 5.2e-153 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKNIKAKF_00871 4.3e-121 G alpha-ribazole phosphatase activity
MKNIKAKF_00872 2.8e-149 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MKNIKAKF_00873 7.6e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MKNIKAKF_00874 2.2e-108 yktB S Belongs to the UPF0637 family
MKNIKAKF_00875 6e-76 yueI S Protein of unknown function (DUF1694)
MKNIKAKF_00876 0.0 gshF 6.3.2.2, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
MKNIKAKF_00877 3e-240 rarA L recombination factor protein RarA
MKNIKAKF_00879 1.1e-38
MKNIKAKF_00880 2.9e-82 usp6 T universal stress protein
MKNIKAKF_00881 6.1e-152 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_00882 3.4e-115 yhfA S HAD hydrolase, family IA, variant 3
MKNIKAKF_00883 5.8e-180 S Protein of unknown function (DUF2785)
MKNIKAKF_00884 2.9e-66 yueI S Protein of unknown function (DUF1694)
MKNIKAKF_00885 2.7e-22
MKNIKAKF_00886 1.1e-280 sufB O assembly protein SufB
MKNIKAKF_00887 1e-78 nifU C SUF system FeS assembly protein, NifU family
MKNIKAKF_00888 1e-218 csdA 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKNIKAKF_00889 1.1e-189 sufD O FeS assembly protein SufD
MKNIKAKF_00890 2.9e-142 sufC O FeS assembly ATPase SufC
MKNIKAKF_00891 3.7e-104 metI P ABC transporter permease
MKNIKAKF_00892 2.3e-190 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKNIKAKF_00893 2e-149 P Belongs to the nlpA lipoprotein family
MKNIKAKF_00894 4e-137 P Belongs to the nlpA lipoprotein family
MKNIKAKF_00895 7.5e-222 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKNIKAKF_00896 9.5e-49 gcvH E glycine cleavage
MKNIKAKF_00897 5.3e-223 rodA D Belongs to the SEDS family
MKNIKAKF_00898 1.1e-30 S Protein of unknown function (DUF2969)
MKNIKAKF_00899 9.1e-55 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MKNIKAKF_00900 2.2e-18 epuA S DNA-directed RNA polymerase subunit beta
MKNIKAKF_00901 9.4e-178 mbl D Cell shape determining protein MreB Mrl
MKNIKAKF_00902 4.2e-31 ywzB S Protein of unknown function (DUF1146)
MKNIKAKF_00903 8.3e-70 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MKNIKAKF_00904 1.3e-244 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKNIKAKF_00905 1.6e-163 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKNIKAKF_00906 9.5e-286 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKNIKAKF_00907 5.9e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNIKAKF_00908 8.6e-39 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKNIKAKF_00909 3.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKNIKAKF_00910 7.9e-126 atpB C it plays a direct role in the translocation of protons across the membrane
MKNIKAKF_00911 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKNIKAKF_00912 4.4e-233 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKNIKAKF_00913 3.1e-184 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKNIKAKF_00914 5.7e-152 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKNIKAKF_00915 5.6e-176 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKNIKAKF_00916 1.3e-110 tdk 2.7.1.21 F thymidine kinase
MKNIKAKF_00917 2.5e-261 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MKNIKAKF_00918 3.5e-196 ampC V Beta-lactamase
MKNIKAKF_00919 2e-163 1.13.11.2 S glyoxalase
MKNIKAKF_00920 3.9e-139 S NADPH-dependent FMN reductase
MKNIKAKF_00921 0.0 yfiC V ABC transporter
MKNIKAKF_00922 0.0 ycfI V ABC transporter, ATP-binding protein
MKNIKAKF_00923 2.2e-119 K Bacterial regulatory proteins, tetR family
MKNIKAKF_00924 7.2e-127 G Phosphoglycerate mutase family
MKNIKAKF_00925 1.6e-07
MKNIKAKF_00927 1.2e-285 pipD E Dipeptidase
MKNIKAKF_00928 1.4e-104 S Protein of unknown function (DUF1211)
MKNIKAKF_00929 3.9e-210 yttB EGP Major facilitator Superfamily
MKNIKAKF_00930 3.2e-13
MKNIKAKF_00931 1.1e-78 tspO T TspO/MBR family
MKNIKAKF_00934 2.9e-78 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ MafB19-like deaminase
MKNIKAKF_00935 1e-173 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MKNIKAKF_00936 6.6e-231 wbbX GT2,GT4 M Glycosyl transferases group 1
MKNIKAKF_00937 3e-43 yttA 2.7.13.3 S Pfam Transposase IS66
MKNIKAKF_00938 1.6e-149 F DNA/RNA non-specific endonuclease
MKNIKAKF_00940 8.6e-47 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
MKNIKAKF_00941 1.3e-134 S Domain of unknown function DUF1829
MKNIKAKF_00942 5.6e-258 pgi 5.3.1.9 G Belongs to the GPI family
MKNIKAKF_00943 5.9e-152 glcU U sugar transport
MKNIKAKF_00944 1.4e-110 vanZ V VanZ like family
MKNIKAKF_00945 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKNIKAKF_00946 5.2e-104
MKNIKAKF_00947 8e-105
MKNIKAKF_00948 1.8e-245 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKNIKAKF_00949 1.9e-203 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKNIKAKF_00950 8.9e-240 pbuX F xanthine permease
MKNIKAKF_00951 1.4e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKNIKAKF_00952 1.9e-115 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
MKNIKAKF_00953 1.2e-82 yvbK 3.1.3.25 K GNAT family
MKNIKAKF_00954 7.9e-31 cspC K Cold shock protein
MKNIKAKF_00955 6.6e-168 yqjA S Putative aromatic acid exporter C-terminal domain
MKNIKAKF_00956 2.7e-77
MKNIKAKF_00957 6.2e-171 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MKNIKAKF_00958 0.0 S Psort location CytoplasmicMembrane, score
MKNIKAKF_00959 2e-88 Q Methyltransferase
MKNIKAKF_00960 4.4e-52 sugE U Multidrug resistance protein
MKNIKAKF_00961 9.5e-135 S -acetyltransferase
MKNIKAKF_00962 4.7e-93 MA20_25245 K FR47-like protein
MKNIKAKF_00963 6.4e-93 hisB 2.7.7.71, 3.1.3.15, 3.1.3.82, 3.1.3.83, 4.2.1.19, 5.3.1.28, 6.3.2.10 GT9 E HAD-hyrolase-like
MKNIKAKF_00964 2.3e-125 1.1.1.1 C nadph quinone reductase
MKNIKAKF_00965 1.7e-54 1.1.1.1 C nadph quinone reductase
MKNIKAKF_00966 8.6e-139 wzb 3.1.3.48 T Tyrosine phosphatase family
MKNIKAKF_00967 4.5e-86 K Acetyltransferase (GNAT) domain
MKNIKAKF_00968 9e-83 yiaC K Acetyltransferase (GNAT) domain
MKNIKAKF_00969 1.2e-74 2.3.1.82 K Acetyltransferase (GNAT) domain
MKNIKAKF_00970 1.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKNIKAKF_00971 4.1e-198 ybiR P Citrate transporter
MKNIKAKF_00972 2.1e-69
MKNIKAKF_00973 7.6e-255 E Peptidase dimerisation domain
MKNIKAKF_00974 1.3e-298 E ABC transporter, substratebinding protein
MKNIKAKF_00975 1e-101
MKNIKAKF_00976 0.0 cadA P P-type ATPase
MKNIKAKF_00977 2.3e-75 hsp3 O Belongs to the small heat shock protein (HSP20) family
MKNIKAKF_00978 4.1e-71 S Iron-sulphur cluster biosynthesis
MKNIKAKF_00979 4.3e-210 htrA 3.4.21.107 O serine protease
MKNIKAKF_00980 1.2e-154 vicX 3.1.26.11 S domain protein
MKNIKAKF_00981 3.1e-139 yycI S YycH protein
MKNIKAKF_00982 1.1e-254 yycH S YycH protein
MKNIKAKF_00983 0.0 vicK 2.7.13.3 T Histidine kinase
MKNIKAKF_00984 8.1e-131 K response regulator
MKNIKAKF_00985 1.5e-121 3.1.1.24 S Alpha/beta hydrolase family
MKNIKAKF_00986 3.5e-258 arpJ P ABC transporter permease
MKNIKAKF_00987 3.7e-232 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKNIKAKF_00988 2.4e-264 argH 4.3.2.1 E argininosuccinate lyase
MKNIKAKF_00989 3.1e-214 S Bacterial protein of unknown function (DUF871)
MKNIKAKF_00990 4.6e-73 S Domain of unknown function (DUF3284)
MKNIKAKF_00991 3.6e-228 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_00992 1.5e-129 K UTRA
MKNIKAKF_00993 2.3e-51 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_00994 2.4e-53 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MKNIKAKF_00995 1.2e-105 speG J Acetyltransferase (GNAT) domain
MKNIKAKF_00996 1.7e-84 F NUDIX domain
MKNIKAKF_00997 1.9e-89 S AAA domain
MKNIKAKF_00998 2.3e-113 ycaC Q Isochorismatase family
MKNIKAKF_00999 7.8e-242 ydiC1 EGP Major Facilitator Superfamily
MKNIKAKF_01000 2.2e-213 yeaN P Transporter, major facilitator family protein
MKNIKAKF_01001 1.6e-171 iolS C Aldo keto reductase
MKNIKAKF_01002 3.4e-64 manO S Domain of unknown function (DUF956)
MKNIKAKF_01003 9.6e-169 manN G system, mannose fructose sorbose family IID component
MKNIKAKF_01004 1.9e-120 manY G PTS system
MKNIKAKF_01005 1.4e-181 manL 2.7.1.191, 2.7.1.206 G PTS system sorbose subfamily IIB component
MKNIKAKF_01006 4.5e-217 EGP Major facilitator Superfamily
MKNIKAKF_01007 6.7e-187 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01008 2.5e-150 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01009 9.6e-158 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01011 9e-287 glnP P ABC transporter permease
MKNIKAKF_01012 3.1e-133 glnQ E ABC transporter, ATP-binding protein
MKNIKAKF_01013 3.4e-31
MKNIKAKF_01014 1.7e-218 G Bacterial extracellular solute-binding protein
MKNIKAKF_01015 3.5e-09 G Bacterial extracellular solute-binding protein
MKNIKAKF_01016 2.2e-128 S Protein of unknown function (DUF975)
MKNIKAKF_01017 4.9e-41 yqkB S Iron-sulphur cluster biosynthesis
MKNIKAKF_01018 1e-51
MKNIKAKF_01019 1e-68 S Bacterial PH domain
MKNIKAKF_01020 3.7e-269 ydbT S Bacterial PH domain
MKNIKAKF_01021 9.1e-144 S AAA ATPase domain
MKNIKAKF_01022 4.3e-166 yniA G Phosphotransferase enzyme family
MKNIKAKF_01023 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKNIKAKF_01024 1.5e-264 glnP P ABC transporter
MKNIKAKF_01025 2.1e-266 glnP P ABC transporter
MKNIKAKF_01026 3.7e-99 ydaF J Acetyltransferase (GNAT) domain
MKNIKAKF_01027 6.7e-105 S Stage II sporulation protein M
MKNIKAKF_01029 1.5e-80 S Uncharacterised protein family (UPF0236)
MKNIKAKF_01030 6e-142 yeaC S ATPase family associated with various cellular activities (AAA)
MKNIKAKF_01031 3e-184 yeaD S Protein of unknown function DUF58
MKNIKAKF_01032 2.3e-306 yebA E Transglutaminase/protease-like homologues
MKNIKAKF_01033 1.1e-214 lsgC M Glycosyl transferases group 1
MKNIKAKF_01034 4.8e-90 maa 2.3.1.79 S Maltose acetyltransferase
MKNIKAKF_01035 2.2e-145 3.1.3.102, 3.1.3.104 G Sucrose-6F-phosphate phosphohydrolase
MKNIKAKF_01036 2.7e-255 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
MKNIKAKF_01037 4.3e-114 S Bacteriocin-protection, YdeI or OmpD-Associated
MKNIKAKF_01038 2.2e-35 yjdF S Protein of unknown function (DUF2992)
MKNIKAKF_01039 1.4e-212 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MKNIKAKF_01040 4e-224 maeN C 2-hydroxycarboxylate transporter family
MKNIKAKF_01041 1.1e-286 dpiB 2.7.13.3 T Single cache domain 3
MKNIKAKF_01042 1.9e-121 dpiA KT cheY-homologous receiver domain
MKNIKAKF_01043 4.8e-35 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
MKNIKAKF_01044 3e-96 1.1.1.31 I NAD binding domain of 6-phosphogluconate dehydrogenase
MKNIKAKF_01045 4.4e-94 M1-431 S Protein of unknown function (DUF1706)
MKNIKAKF_01046 7.7e-25
MKNIKAKF_01047 6.9e-221 yagE E Amino acid permease
MKNIKAKF_01048 8e-171 O protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
MKNIKAKF_01049 8.7e-225 ptsG G phosphotransferase system
MKNIKAKF_01050 4.5e-40 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKNIKAKF_01052 5.5e-63 ligA 2.7.7.7, 6.5.1.2 L EXOIII
MKNIKAKF_01053 1.2e-186 cggR K Putative sugar-binding domain
MKNIKAKF_01054 2.8e-193 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKNIKAKF_01055 4.4e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MKNIKAKF_01056 7.8e-140 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKNIKAKF_01057 9e-245 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKNIKAKF_01058 6.7e-229 mdt(A) EGP Major facilitator Superfamily
MKNIKAKF_01059 1.1e-47
MKNIKAKF_01060 1.4e-292 clcA P chloride
MKNIKAKF_01061 2.4e-31 secG U Preprotein translocase
MKNIKAKF_01062 3.8e-139 est 3.1.1.1 S Serine aminopeptidase, S33
MKNIKAKF_01063 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKNIKAKF_01064 9.4e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MKNIKAKF_01065 1.3e-176 yvdE K helix_turn _helix lactose operon repressor
MKNIKAKF_01066 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MKNIKAKF_01067 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MKNIKAKF_01068 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MKNIKAKF_01069 3.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
MKNIKAKF_01070 4.3e-211 msmX P Belongs to the ABC transporter superfamily
MKNIKAKF_01071 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
MKNIKAKF_01072 3.2e-223 malE G Bacterial extracellular solute-binding protein
MKNIKAKF_01073 1.5e-242 malF P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01074 5.5e-150 malG P ABC transporter permease
MKNIKAKF_01075 1.7e-21
MKNIKAKF_01076 1.6e-22 ydcG K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01077 7.8e-238 YSH1 S Metallo-beta-lactamase superfamily
MKNIKAKF_01078 9.8e-231 malE G Bacterial extracellular solute-binding protein
MKNIKAKF_01079 1.9e-147 malF G Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01080 1.7e-165 malG P ABC-type sugar transport systems, permease components
MKNIKAKF_01081 3.5e-194 malK P ATPases associated with a variety of cellular activities
MKNIKAKF_01082 3.1e-104 3.2.2.20 K Acetyltransferase (GNAT) domain
MKNIKAKF_01083 9e-92 yxjI
MKNIKAKF_01084 3.1e-156 ycsE S Sucrose-6F-phosphate phosphohydrolase
MKNIKAKF_01085 7.3e-129 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKNIKAKF_01086 6.7e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MKNIKAKF_01087 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MKNIKAKF_01089 1.8e-167 natA S ABC transporter, ATP-binding protein
MKNIKAKF_01090 3.6e-214 ysdA CP ABC-2 family transporter protein
MKNIKAKF_01091 2.4e-98 dnaQ 2.7.7.7 L DNA polymerase III
MKNIKAKF_01092 7.5e-151 xth 3.1.11.2 L exodeoxyribonuclease III
MKNIKAKF_01093 2.4e-167 murB 1.3.1.98 M Cell wall formation
MKNIKAKF_01094 0.0 yjcE P Sodium proton antiporter
MKNIKAKF_01095 2.9e-96 puuR K Cupin domain
MKNIKAKF_01096 1e-204 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKNIKAKF_01097 5.5e-147 potB P ABC transporter permease
MKNIKAKF_01098 1.2e-141 potC P ABC transporter permease
MKNIKAKF_01099 2.3e-206 potD P ABC transporter
MKNIKAKF_01101 0.0 pacL 3.6.3.8, 3.6.3.9 P Cation transporter/ATPase, N-terminus
MKNIKAKF_01102 7.2e-110 K Transcriptional regulator
MKNIKAKF_01103 2.5e-182 V ABC transporter
MKNIKAKF_01104 2.3e-128 V AAA domain, putative AbiEii toxin, Type IV TA system
MKNIKAKF_01105 2.2e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKNIKAKF_01106 2.2e-164 ybbR S YbbR-like protein
MKNIKAKF_01107 2.6e-255 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKNIKAKF_01108 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKNIKAKF_01110 0.0 pepF2 E Oligopeptidase F
MKNIKAKF_01111 1.5e-78 S VanZ like family
MKNIKAKF_01112 7.6e-132 yebC K Transcriptional regulatory protein
MKNIKAKF_01113 2.7e-152 comGA NU Type II IV secretion system protein
MKNIKAKF_01114 6.9e-170 comGB NU type II secretion system
MKNIKAKF_01115 2.5e-26
MKNIKAKF_01117 2.5e-23
MKNIKAKF_01118 1.9e-19
MKNIKAKF_01119 9.7e-10
MKNIKAKF_01120 8.1e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
MKNIKAKF_01121 5.4e-51
MKNIKAKF_01122 2.4e-256 cycA E Amino acid permease
MKNIKAKF_01123 6.7e-147 arbV 2.3.1.51 I Phosphate acyltransferases
MKNIKAKF_01124 2.5e-163 arbx M Glycosyl transferase family 8
MKNIKAKF_01125 3.6e-182 arbY M family 8
MKNIKAKF_01126 2.8e-165 arbZ I Phosphate acyltransferases
MKNIKAKF_01127 0.0 rafA 3.2.1.22 G alpha-galactosidase
MKNIKAKF_01130 5.8e-70 S SdpI/YhfL protein family
MKNIKAKF_01131 2.1e-134 K response regulator
MKNIKAKF_01132 2.9e-271 T PhoQ Sensor
MKNIKAKF_01133 3.6e-75 yhbS S acetyltransferase
MKNIKAKF_01134 5.3e-14
MKNIKAKF_01135 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MKNIKAKF_01137 1.1e-254 bmr3 EGP Major facilitator Superfamily
MKNIKAKF_01138 1e-99 yobS K Bacterial regulatory proteins, tetR family
MKNIKAKF_01139 1.3e-245 yhgE V domain protein
MKNIKAKF_01140 4e-47 S Thiamine-binding protein
MKNIKAKF_01141 3.2e-138 magIII L Base excision DNA repair protein, HhH-GPD family
MKNIKAKF_01142 1.1e-158 pphA 3.1.3.16 T Calcineurin-like phosphoesterase superfamily domain
MKNIKAKF_01143 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKNIKAKF_01144 1.1e-253 rarA L recombination factor protein RarA
MKNIKAKF_01145 1.2e-57
MKNIKAKF_01146 7.7e-172 yhaI S Protein of unknown function (DUF805)
MKNIKAKF_01147 1.7e-268 L Mga helix-turn-helix domain
MKNIKAKF_01149 1.1e-182 ynjC S Cell surface protein
MKNIKAKF_01150 3.8e-123 S WxL domain surface cell wall-binding
MKNIKAKF_01151 1.3e-121 S WxL domain surface cell wall-binding
MKNIKAKF_01153 0.0
MKNIKAKF_01154 5.8e-103 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKNIKAKF_01155 4.9e-29
MKNIKAKF_01156 1.7e-179 mhqA 3.4.21.26 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKNIKAKF_01157 6.3e-46 S DsrE/DsrF-like family
MKNIKAKF_01158 9.1e-254 pbuO S permease
MKNIKAKF_01159 1.4e-41 S Protein of unknown function (DUF1516)
MKNIKAKF_01160 2e-53 ypaA S Protein of unknown function (DUF1304)
MKNIKAKF_01161 2e-161 1.6.5.5 C alcohol dehydrogenase
MKNIKAKF_01162 3.2e-81 slyA K Transcriptional regulator
MKNIKAKF_01163 2.3e-42
MKNIKAKF_01164 1.1e-192 ldhD3 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNIKAKF_01165 2.6e-88 ogt 2.1.1.63 L Methyltransferase
MKNIKAKF_01166 4e-206 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MKNIKAKF_01167 1.5e-42
MKNIKAKF_01168 7.3e-208 mccF V LD-carboxypeptidase
MKNIKAKF_01169 1.8e-181 I PAP2 superfamily
MKNIKAKF_01170 4.8e-42 S Protein of unknown function (DUF2089)
MKNIKAKF_01171 1e-36
MKNIKAKF_01172 2.4e-256 C COG0277 FAD FMN-containing dehydrogenases
MKNIKAKF_01173 5.5e-141 T Calcineurin-like phosphoesterase superfamily domain
MKNIKAKF_01174 3.3e-258
MKNIKAKF_01175 2.4e-99 K Bacteriophage CI repressor helix-turn-helix domain
MKNIKAKF_01177 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MKNIKAKF_01178 2.7e-132 S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
MKNIKAKF_01179 1e-165 yxlF V ABC transporter
MKNIKAKF_01180 4.8e-34 S Phospholipase_D-nuclease N-terminal
MKNIKAKF_01181 4.3e-203 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01182 2.3e-159 lysR5 K LysR substrate binding domain
MKNIKAKF_01183 0.0 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
MKNIKAKF_01184 1.1e-56 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MKNIKAKF_01185 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MKNIKAKF_01186 2.4e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKNIKAKF_01187 1.8e-119 K Helix-turn-helix domain, rpiR family
MKNIKAKF_01188 7.6e-129 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKNIKAKF_01189 1.1e-273 sacX 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKNIKAKF_01190 5.4e-217
MKNIKAKF_01191 4.6e-247 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MKNIKAKF_01192 9e-75 rplI J Binds to the 23S rRNA
MKNIKAKF_01193 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MKNIKAKF_01194 3.7e-94 V ABC transporter, ATP-binding protein
MKNIKAKF_01196 0.0 helD 3.6.4.12 L DNA helicase
MKNIKAKF_01197 8.6e-148 rlrG K Transcriptional regulator
MKNIKAKF_01198 4.5e-172 shetA P Voltage-dependent anion channel
MKNIKAKF_01199 2.8e-114 S CAAX protease self-immunity
MKNIKAKF_01201 1.6e-115 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKNIKAKF_01202 4e-69 K MarR family
MKNIKAKF_01203 0.0 uvrA3 L excinuclease ABC
MKNIKAKF_01204 8.1e-193 yghZ C Aldo keto reductase family protein
MKNIKAKF_01205 7.3e-144 S hydrolase
MKNIKAKF_01206 8.1e-60
MKNIKAKF_01207 4.1e-11
MKNIKAKF_01208 6.2e-104 yoaK S Protein of unknown function (DUF1275)
MKNIKAKF_01209 6.4e-125 yjhF G Phosphoglycerate mutase family
MKNIKAKF_01210 4.3e-152 yitU 3.1.3.104 S hydrolase
MKNIKAKF_01211 9.8e-88 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKNIKAKF_01212 1.7e-165 K LysR substrate binding domain
MKNIKAKF_01213 1.3e-226 EK Aminotransferase, class I
MKNIKAKF_01214 4.9e-181 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKNIKAKF_01215 2e-118 ydfK S Protein of unknown function (DUF554)
MKNIKAKF_01216 2.5e-88
MKNIKAKF_01217 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNIKAKF_01218 3.3e-172 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
MKNIKAKF_01219 2.8e-129 rpl K Helix-turn-helix domain, rpiR family
MKNIKAKF_01220 1.2e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKNIKAKF_01221 1.9e-132 L Transposase, IS116 IS110 IS902 family
MKNIKAKF_01223 1.1e-293 plyA3 M Right handed beta helix region
MKNIKAKF_01224 8.5e-62
MKNIKAKF_01225 0.0 M Heparinase II/III N-terminus
MKNIKAKF_01227 5.1e-81 G PTS system fructose IIA component
MKNIKAKF_01228 5.6e-144 agaD G PTS system mannose/fructose/sorbose family IID component
MKNIKAKF_01229 4.3e-144 G PTS system sorbose-specific iic component
MKNIKAKF_01230 1.2e-88 agaV 2.7.1.191 G PTS system sorbose subfamily IIB component
MKNIKAKF_01231 2e-235 ugl 3.2.1.180 GH88 S Glycosyl Hydrolase Family 88
MKNIKAKF_01232 4.5e-157 Z012_03480 S Psort location Cytoplasmic, score
MKNIKAKF_01233 5.1e-139 K Bacterial transcriptional regulator
MKNIKAKF_01234 7.3e-163 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
MKNIKAKF_01235 4.8e-151 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
MKNIKAKF_01236 1.8e-116 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
MKNIKAKF_01237 1.5e-194 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
MKNIKAKF_01238 3.5e-117 alkD L DNA alkylation repair enzyme
MKNIKAKF_01239 3.4e-126 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKNIKAKF_01240 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKNIKAKF_01241 1.2e-169 ykoT GT2 M Glycosyl transferase family 2
MKNIKAKF_01242 1.4e-119 lssY 3.6.1.27 I phosphatase
MKNIKAKF_01243 8e-117 dedA S SNARE-like domain protein
MKNIKAKF_01244 1e-238 T PhoQ Sensor
MKNIKAKF_01245 1.6e-126 K Transcriptional regulatory protein, C terminal
MKNIKAKF_01247 1.5e-17
MKNIKAKF_01248 2e-238 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
MKNIKAKF_01249 1e-182 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MKNIKAKF_01250 4.4e-104 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
MKNIKAKF_01251 0.0 4.2.2.1 PL8 N Polysaccharide lyase family 8, N terminal alpha-helical domain
MKNIKAKF_01252 5.4e-192 S Protein of unknown function C-terminal (DUF3324)
MKNIKAKF_01253 1.2e-87
MKNIKAKF_01254 2e-18 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MKNIKAKF_01255 1.3e-116 sodA 1.15.1.1 C Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MKNIKAKF_01256 1.3e-157 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MKNIKAKF_01257 8.9e-158 I alpha/beta hydrolase fold
MKNIKAKF_01258 1.6e-28
MKNIKAKF_01259 9.3e-74
MKNIKAKF_01260 6.8e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MKNIKAKF_01261 1.1e-124 citR K FCD
MKNIKAKF_01262 3.4e-266 oadA 2.1.3.1, 4.1.1.3, 6.4.1.1, 6.4.1.7 C Conserved carboxylase domain
MKNIKAKF_01263 6.9e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MKNIKAKF_01264 5.9e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MKNIKAKF_01265 9e-156 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MKNIKAKF_01266 1.3e-48 citD C Covalent carrier of the coenzyme of citrate lyase
MKNIKAKF_01267 1e-179 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MKNIKAKF_01269 1.8e-196 oadB 4.1.1.3 C Na+-transporting oxaloacetate decarboxylase beta subunit
MKNIKAKF_01270 6.2e-40 gcdC 2.3.1.12 I Biotin-requiring enzyme
MKNIKAKF_01271 1.2e-52
MKNIKAKF_01272 4.8e-241 citM C Citrate transporter
MKNIKAKF_01273 2.8e-41
MKNIKAKF_01274 5.1e-104 kptA J Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
MKNIKAKF_01275 1.6e-88 K GNAT family
MKNIKAKF_01276 1.2e-106 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MKNIKAKF_01277 9.7e-58 K Transcriptional regulator PadR-like family
MKNIKAKF_01278 1.2e-88 ORF00048
MKNIKAKF_01279 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MKNIKAKF_01280 2.6e-169 yjjC V ABC transporter
MKNIKAKF_01281 2.9e-293 M Exporter of polyketide antibiotics
MKNIKAKF_01282 9.6e-115 K Transcriptional regulator
MKNIKAKF_01283 4.1e-259 EGP Major facilitator Superfamily
MKNIKAKF_01284 6.2e-126 S membrane transporter protein
MKNIKAKF_01285 9.5e-181 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01286 1.3e-159 S Alpha beta hydrolase
MKNIKAKF_01287 1.2e-59 yvoA_1 K Transcriptional regulator, GntR family
MKNIKAKF_01288 1.1e-124 skfE V ATPases associated with a variety of cellular activities
MKNIKAKF_01289 6.7e-19
MKNIKAKF_01290 2.6e-141
MKNIKAKF_01291 1.1e-87 V ATPases associated with a variety of cellular activities
MKNIKAKF_01292 6.7e-96 ydaF J Acetyltransferase (GNAT) domain
MKNIKAKF_01293 7.4e-158 oppF P Oligopeptide/dipeptide transporter, C-terminal region
MKNIKAKF_01294 9.6e-200 oppD P Oligopeptide/dipeptide transporter, C-terminal region
MKNIKAKF_01295 8.5e-24
MKNIKAKF_01296 7.4e-175 amiD EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKNIKAKF_01297 4.2e-167 oppB P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01298 6.9e-290 E Bacterial extracellular solute-binding proteins, family 5 Middle
MKNIKAKF_01299 1.6e-128 hchA S DJ-1/PfpI family
MKNIKAKF_01300 4.6e-52 K Transcriptional
MKNIKAKF_01301 2.1e-36
MKNIKAKF_01302 2.4e-131 V ABC transporter transmembrane region
MKNIKAKF_01303 2.9e-88 V ABC transporter transmembrane region
MKNIKAKF_01304 3.1e-215 V ABC transporter transmembrane region
MKNIKAKF_01306 4.6e-67 S Iron-sulphur cluster biosynthesis
MKNIKAKF_01307 1.4e-15 2.7.1.39 S Phosphotransferase enzyme family
MKNIKAKF_01308 2.2e-253 lytN 3.5.1.104 M LysM domain
MKNIKAKF_01309 3.4e-135 zmp3 O Zinc-dependent metalloprotease
MKNIKAKF_01311 2.8e-129 repA K DeoR C terminal sensor domain
MKNIKAKF_01314 1e-48 lciIC K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01315 1.5e-86 yjdB S Domain of unknown function (DUF4767)
MKNIKAKF_01316 2.8e-221 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKNIKAKF_01317 3.6e-193 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MKNIKAKF_01318 2.5e-280 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MKNIKAKF_01319 8.6e-163 K Transcriptional regulator
MKNIKAKF_01320 7.6e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MKNIKAKF_01323 2.1e-85 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNIKAKF_01324 1.4e-50 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_01325 1.6e-266 gatC G PTS system sugar-specific permease component
MKNIKAKF_01326 5.6e-26
MKNIKAKF_01327 4.6e-123 S Domain of unknown function (DUF4867)
MKNIKAKF_01328 4.9e-176 lacC 2.7.1.11, 2.7.1.144, 2.7.1.56 H pfkB family carbohydrate kinase
MKNIKAKF_01329 2.5e-186 yihT 4.1.2.40, 4.1.2.57 G Belongs to the aldolase LacD family
MKNIKAKF_01330 2.9e-93 rpiB 2.1.1.222, 2.1.1.64, 5.3.1.26, 5.3.1.6 G Ribose/Galactose Isomerase
MKNIKAKF_01331 2.7e-73 lacA 5.3.1.26 G Ribose/Galactose Isomerase
MKNIKAKF_01332 4.2e-141 lacR K DeoR C terminal sensor domain
MKNIKAKF_01333 3.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MKNIKAKF_01334 6.2e-210 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKNIKAKF_01335 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MKNIKAKF_01336 2.1e-14
MKNIKAKF_01337 2.2e-76 hsp1 O Belongs to the small heat shock protein (HSP20) family
MKNIKAKF_01339 4.2e-211 mutY L A G-specific adenine glycosylase
MKNIKAKF_01340 2.5e-149 cytC6 I alpha/beta hydrolase fold
MKNIKAKF_01341 2.1e-120 yrkL S Flavodoxin-like fold
MKNIKAKF_01343 1.5e-86 S Short repeat of unknown function (DUF308)
MKNIKAKF_01344 4.1e-118 S Psort location Cytoplasmic, score
MKNIKAKF_01345 1.6e-154 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MKNIKAKF_01346 1.4e-195
MKNIKAKF_01347 3.9e-07
MKNIKAKF_01348 1.5e-115 ywnB S NAD(P)H-binding
MKNIKAKF_01349 0.0 bglB 3.2.1.21 GH3 G hydrolase, family 3
MKNIKAKF_01350 6.1e-166 XK27_00670 S ABC transporter substrate binding protein
MKNIKAKF_01351 3.1e-165 XK27_00670 S ABC transporter
MKNIKAKF_01352 1.9e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
MKNIKAKF_01353 8.8e-142 cmpC S ABC transporter, ATP-binding protein
MKNIKAKF_01354 8e-174 yhfP 1.1.1.1 C Zinc-binding dehydrogenase
MKNIKAKF_01355 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
MKNIKAKF_01356 6.2e-182 ykcC GT2 M Glycosyl transferase family 2
MKNIKAKF_01357 0.0 ykcB M Dolichyl-phosphate-mannose-protein mannosyltransferase
MKNIKAKF_01358 4.1e-71 S GtrA-like protein
MKNIKAKF_01359 5.3e-124 K cheY-homologous receiver domain
MKNIKAKF_01360 2.7e-241 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
MKNIKAKF_01361 3.1e-68 yqkB S Belongs to the HesB IscA family
MKNIKAKF_01362 1.4e-92 QT PucR C-terminal helix-turn-helix domain
MKNIKAKF_01363 1.4e-165 QT PucR C-terminal helix-turn-helix domain
MKNIKAKF_01364 1.4e-161 ptlF S KR domain
MKNIKAKF_01365 1.4e-158 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MKNIKAKF_01366 1.1e-121 drgA C Nitroreductase family
MKNIKAKF_01367 1.2e-68 lctO C IMP dehydrogenase / GMP reductase domain
MKNIKAKF_01368 1.1e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MKNIKAKF_01369 2.4e-80 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKNIKAKF_01370 1.9e-107 K Bacterial regulatory proteins, tetR family
MKNIKAKF_01371 2.1e-183 yxeA V FtsX-like permease family
MKNIKAKF_01372 4.6e-126 devA 3.6.3.25 V ATPases associated with a variety of cellular activities
MKNIKAKF_01373 1.1e-33
MKNIKAKF_01374 1.3e-110 tipA K TipAS antibiotic-recognition domain
MKNIKAKF_01375 1.1e-20 M1-1017
MKNIKAKF_01376 8.2e-33 K Transcriptional regulator PadR-like family
MKNIKAKF_01377 3.2e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKNIKAKF_01378 8.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNIKAKF_01379 6e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNIKAKF_01380 1.6e-154 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKNIKAKF_01381 4.5e-115
MKNIKAKF_01382 4.8e-61 rplQ J Ribosomal protein L17
MKNIKAKF_01383 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNIKAKF_01384 4e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKNIKAKF_01385 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKNIKAKF_01386 6.6e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MKNIKAKF_01387 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKNIKAKF_01388 4.6e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKNIKAKF_01389 2e-231 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKNIKAKF_01390 6.5e-62 rplO J Binds to the 23S rRNA
MKNIKAKF_01391 3.9e-24 rpmD J Ribosomal protein L30
MKNIKAKF_01392 1.2e-83 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKNIKAKF_01393 1.8e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKNIKAKF_01394 1.7e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKNIKAKF_01395 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKNIKAKF_01396 8.5e-96 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKNIKAKF_01397 6.9e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKNIKAKF_01398 2.1e-58 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKNIKAKF_01399 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKNIKAKF_01400 1.1e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MKNIKAKF_01401 2.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKNIKAKF_01402 6.2e-109 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKNIKAKF_01403 1.1e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKNIKAKF_01404 2.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKNIKAKF_01405 2.9e-156 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKNIKAKF_01406 2e-46 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKNIKAKF_01407 1.7e-108 rplD J Forms part of the polypeptide exit tunnel
MKNIKAKF_01408 4e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKNIKAKF_01409 2e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MKNIKAKF_01410 3.5e-68 psiE S Phosphate-starvation-inducible E
MKNIKAKF_01411 1.9e-106 ahpC 1.11.1.15 O C-terminal domain of 1-Cys peroxiredoxin
MKNIKAKF_01412 1e-198 yfjR K WYL domain
MKNIKAKF_01413 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKNIKAKF_01414 8.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKNIKAKF_01415 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKNIKAKF_01416 0.0 M domain protein
MKNIKAKF_01417 0.0 M domain protein
MKNIKAKF_01418 3.1e-36 3.4.23.43
MKNIKAKF_01419 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNIKAKF_01420 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKNIKAKF_01421 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKNIKAKF_01422 4.3e-80 ctsR K Belongs to the CtsR family
MKNIKAKF_01431 2.1e-85 ykuL S CBS domain
MKNIKAKF_01432 2.5e-135 gla U Major intrinsic protein
MKNIKAKF_01433 2.5e-97 S Phosphoesterase
MKNIKAKF_01434 3.8e-276 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MKNIKAKF_01435 8.8e-84 yslB S Protein of unknown function (DUF2507)
MKNIKAKF_01436 1.5e-244 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKNIKAKF_01437 1.2e-36 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKNIKAKF_01438 2.6e-238 dltB M MBOAT, membrane-bound O-acyltransferase family
MKNIKAKF_01439 1.1e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKNIKAKF_01440 6.1e-20 dltX S D-Ala-teichoic acid biosynthesis protein
MKNIKAKF_01441 6.6e-53 trxA O Belongs to the thioredoxin family
MKNIKAKF_01442 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKNIKAKF_01443 9.6e-92 cvpA S Colicin V production protein
MKNIKAKF_01444 5.8e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKNIKAKF_01445 6.8e-53 yrzB S Belongs to the UPF0473 family
MKNIKAKF_01446 1.6e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKNIKAKF_01447 4e-43 yrzL S Belongs to the UPF0297 family
MKNIKAKF_01449 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKNIKAKF_01450 7.8e-174
MKNIKAKF_01451 4.3e-250 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKNIKAKF_01452 3.7e-179 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MKNIKAKF_01453 2.3e-240 ytoI K DRTGG domain
MKNIKAKF_01454 1.2e-205 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKNIKAKF_01455 3.3e-291 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKNIKAKF_01456 2.3e-116 sirR K Helix-turn-helix diphteria tox regulatory element
MKNIKAKF_01457 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MKNIKAKF_01458 1.2e-65 yajC U Preprotein translocase
MKNIKAKF_01459 2.3e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKNIKAKF_01460 2.1e-207 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKNIKAKF_01461 3.2e-189 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKNIKAKF_01462 6e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKNIKAKF_01463 1.4e-104 yjbF S SNARE associated Golgi protein
MKNIKAKF_01464 2.2e-87 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKNIKAKF_01465 1.6e-221 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MKNIKAKF_01467 3.5e-74 S Protein of unknown function (DUF3290)
MKNIKAKF_01468 6.6e-119 yviA S Protein of unknown function (DUF421)
MKNIKAKF_01469 2e-144 S Alpha beta hydrolase
MKNIKAKF_01470 1.7e-155
MKNIKAKF_01471 1.3e-156 dkgB S reductase
MKNIKAKF_01472 2.5e-83 nrdI F Belongs to the NrdI family
MKNIKAKF_01473 5.2e-178 D Alpha beta
MKNIKAKF_01474 3.3e-77 K Transcriptional regulator
MKNIKAKF_01475 8.5e-122 gph 3.1.3.18 S haloacid dehalogenase-like hydrolase
MKNIKAKF_01476 8.7e-199 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKNIKAKF_01477 2.6e-94 cysE 2.3.1.178 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKNIKAKF_01478 2.6e-45
MKNIKAKF_01479 1.9e-180 3.4.11.5 I carboxylic ester hydrolase activity
MKNIKAKF_01480 0.0 yfgQ P E1-E2 ATPase
MKNIKAKF_01481 1.9e-80 ndk 2.7.4.6 F Belongs to the NDK family
MKNIKAKF_01482 4.4e-132 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNIKAKF_01485 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKNIKAKF_01486 5.2e-198 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MKNIKAKF_01487 3.1e-14
MKNIKAKF_01489 3.8e-201 M Glycosyltransferase like family 2
MKNIKAKF_01490 8.2e-159 map 3.4.11.18 E Methionine Aminopeptidase
MKNIKAKF_01491 7.2e-80 fld C Flavodoxin
MKNIKAKF_01492 6e-180 yihY S Belongs to the UPF0761 family
MKNIKAKF_01493 2.6e-258 S Uncharacterized protein conserved in bacteria (DUF2252)
MKNIKAKF_01494 2.1e-111 K Bacterial regulatory proteins, tetR family
MKNIKAKF_01495 2.7e-238 pepS E Thermophilic metalloprotease (M29)
MKNIKAKF_01496 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MKNIKAKF_01497 7.5e-07
MKNIKAKF_01499 7.3e-71 S Domain of unknown function (DUF3284)
MKNIKAKF_01500 7.6e-56 chbA 2.7.1.196, 2.7.1.205 G phosphoenolpyruvate-dependent sugar phosphotransferase system
MKNIKAKF_01501 1.1e-223 yfmL 3.6.4.13 L DEAD DEAH box helicase
MKNIKAKF_01502 2.5e-175 mocA S Oxidoreductase
MKNIKAKF_01503 1.7e-60 S Domain of unknown function (DUF4828)
MKNIKAKF_01504 2.2e-60 S Protein of unknown function (DUF1093)
MKNIKAKF_01505 9.3e-138 lys M Glycosyl hydrolases family 25
MKNIKAKF_01506 1.2e-28
MKNIKAKF_01507 1.9e-119 qmcA O prohibitin homologues
MKNIKAKF_01508 1.2e-165 degV S Uncharacterised protein, DegV family COG1307
MKNIKAKF_01509 1.1e-78 K Acetyltransferase (GNAT) family
MKNIKAKF_01510 5e-265 ydiC1 EGP Major facilitator Superfamily
MKNIKAKF_01511 0.0 pepO 3.4.24.71 O Peptidase family M13
MKNIKAKF_01512 1.5e-163 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MKNIKAKF_01513 2e-144 cof S Sucrose-6F-phosphate phosphohydrolase
MKNIKAKF_01514 3.6e-219 yttB EGP Major facilitator Superfamily
MKNIKAKF_01515 1.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKNIKAKF_01516 4.4e-194 yegS 2.7.1.107 G Lipid kinase
MKNIKAKF_01517 8e-279 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNIKAKF_01518 5.1e-265 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKNIKAKF_01519 3.7e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKNIKAKF_01520 3.4e-211 camS S sex pheromone
MKNIKAKF_01521 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKNIKAKF_01522 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MKNIKAKF_01524 8.4e-27 yjgN S Bacterial protein of unknown function (DUF898)
MKNIKAKF_01525 1.3e-129 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
MKNIKAKF_01526 2e-190 S response to antibiotic
MKNIKAKF_01528 1.2e-252 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
MKNIKAKF_01529 1.3e-54
MKNIKAKF_01530 1e-63
MKNIKAKF_01531 1.5e-71 pheB 5.4.99.5 S Belongs to the UPF0735 family
MKNIKAKF_01532 1.4e-298 oppA E ABC transporter, substratebinding protein
MKNIKAKF_01533 4.1e-83
MKNIKAKF_01534 3e-53
MKNIKAKF_01535 1.3e-67
MKNIKAKF_01536 1.5e-89 V ATPases associated with a variety of cellular activities
MKNIKAKF_01537 1.1e-43
MKNIKAKF_01538 6.4e-76 S NUDIX domain
MKNIKAKF_01539 1.2e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
MKNIKAKF_01540 1.9e-225 V ABC transporter transmembrane region
MKNIKAKF_01541 1.4e-111 gadR K Helix-turn-helix XRE-family like proteins
MKNIKAKF_01542 0.0 fnq20 1.13.12.16 S FAD-NAD(P)-binding
MKNIKAKF_01543 7.2e-261 nox 1.6.3.4 C NADH oxidase
MKNIKAKF_01544 1.7e-116
MKNIKAKF_01545 5.6e-218 S TPM domain
MKNIKAKF_01546 4.6e-125 yxaA S Sulfite exporter TauE/SafE
MKNIKAKF_01547 1e-55 ywjH S Protein of unknown function (DUF1634)
MKNIKAKF_01549 6.5e-90
MKNIKAKF_01550 2.8e-48
MKNIKAKF_01551 2.4e-83 fld C Flavodoxin
MKNIKAKF_01552 1.2e-36
MKNIKAKF_01553 1.1e-26
MKNIKAKF_01554 1.9e-170 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNIKAKF_01555 1.4e-71 pdxH S Pyridoxamine 5'-phosphate oxidase
MKNIKAKF_01556 3.5e-39 S Transglycosylase associated protein
MKNIKAKF_01557 5.3e-82 S Protein conserved in bacteria
MKNIKAKF_01558 2.8e-25
MKNIKAKF_01559 7.4e-68 asp23 S Asp23 family, cell envelope-related function
MKNIKAKF_01560 1.6e-62 asp2 S Asp23 family, cell envelope-related function
MKNIKAKF_01562 3.3e-113 S Protein of unknown function (DUF969)
MKNIKAKF_01563 3.7e-152 S Protein of unknown function (DUF979)
MKNIKAKF_01564 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
MKNIKAKF_01565 6.5e-108 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MKNIKAKF_01566 3e-127 cobQ S glutamine amidotransferase
MKNIKAKF_01567 1.3e-66
MKNIKAKF_01568 4.1e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MKNIKAKF_01569 4e-137 noc K Belongs to the ParB family
MKNIKAKF_01570 9.7e-138 soj D Sporulation initiation inhibitor
MKNIKAKF_01571 5.2e-156 spo0J K Belongs to the ParB family
MKNIKAKF_01572 1.8e-29 yyzM S Bacterial protein of unknown function (DUF951)
MKNIKAKF_01573 1.3e-185 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKNIKAKF_01574 3e-105 XK27_01040 S Protein of unknown function (DUF1129)
MKNIKAKF_01575 2.5e-275 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKNIKAKF_01576 4.7e-120
MKNIKAKF_01577 1.9e-121 K response regulator
MKNIKAKF_01578 3.9e-218 hpk31 2.7.13.3 T Histidine kinase
MKNIKAKF_01579 1.8e-237 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MKNIKAKF_01580 8.6e-68 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKNIKAKF_01581 3.6e-293 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKNIKAKF_01582 1.8e-141 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MKNIKAKF_01583 1e-164 yvgN C Aldo keto reductase
MKNIKAKF_01584 2.5e-123 gntR K rpiR family
MKNIKAKF_01585 1.2e-168 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
MKNIKAKF_01586 1.9e-305 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MKNIKAKF_01587 6.7e-64 gntP EG Gluconate
MKNIKAKF_01588 9.2e-231 cinA 3.5.1.42 S Belongs to the CinA family
MKNIKAKF_01589 4.7e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKNIKAKF_01590 3.1e-231 rny S Endoribonuclease that initiates mRNA decay
MKNIKAKF_01591 2.6e-115 yvyE 3.4.13.9 S YigZ family
MKNIKAKF_01592 1.7e-235 comFA L Helicase C-terminal domain protein
MKNIKAKF_01593 6.6e-82 comFC S Competence protein
MKNIKAKF_01594 2.1e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKNIKAKF_01595 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKNIKAKF_01596 3.9e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKNIKAKF_01597 5.4e-124 ftsE D ABC transporter
MKNIKAKF_01599 3.6e-202 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MKNIKAKF_01600 2.4e-130 K response regulator
MKNIKAKF_01601 1.1e-308 phoR 2.7.13.3 T Histidine kinase
MKNIKAKF_01602 1.2e-152 pstS P Phosphate
MKNIKAKF_01603 3.6e-155 pstC P probably responsible for the translocation of the substrate across the membrane
MKNIKAKF_01604 4.8e-157 pstA P Phosphate transport system permease protein PstA
MKNIKAKF_01605 4.5e-149 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNIKAKF_01606 9.3e-141 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKNIKAKF_01607 1e-119 phoU P Plays a role in the regulation of phosphate uptake
MKNIKAKF_01608 2.4e-262 yvlB S Putative adhesin
MKNIKAKF_01609 1.4e-30
MKNIKAKF_01610 7.4e-34 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MKNIKAKF_01611 2.1e-174 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKNIKAKF_01612 9.5e-166 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKNIKAKF_01613 6.9e-195 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MKNIKAKF_01614 2.4e-178 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKNIKAKF_01615 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MKNIKAKF_01616 2.2e-114 T Transcriptional regulatory protein, C terminal
MKNIKAKF_01617 1.7e-174 T His Kinase A (phosphoacceptor) domain
MKNIKAKF_01618 4.5e-91 V ABC transporter
MKNIKAKF_01619 0.0 V FtsX-like permease family
MKNIKAKF_01620 6.5e-119 yfbR S HD containing hydrolase-like enzyme
MKNIKAKF_01621 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKNIKAKF_01622 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKNIKAKF_01623 8.7e-85 S Short repeat of unknown function (DUF308)
MKNIKAKF_01624 9.7e-166 rapZ S Displays ATPase and GTPase activities
MKNIKAKF_01625 2.4e-192 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MKNIKAKF_01626 8.2e-171 whiA K May be required for sporulation
MKNIKAKF_01627 3.2e-80 ohrR K helix_turn_helix multiple antibiotic resistance protein
MKNIKAKF_01628 1.9e-101 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKNIKAKF_01634 3.9e-71
MKNIKAKF_01635 1.1e-209 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKNIKAKF_01636 3.8e-263 emrY EGP Major facilitator Superfamily
MKNIKAKF_01637 4.3e-80 merR K MerR HTH family regulatory protein
MKNIKAKF_01638 6.2e-266 lmrB EGP Major facilitator Superfamily
MKNIKAKF_01639 5.2e-109 S Domain of unknown function (DUF4811)
MKNIKAKF_01640 2.4e-119 3.6.1.27 I Acid phosphatase homologues
MKNIKAKF_01641 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKNIKAKF_01642 2.2e-280 ytgP S Polysaccharide biosynthesis protein
MKNIKAKF_01643 2.2e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKNIKAKF_01644 4e-33 yhcC S Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082)
MKNIKAKF_01645 4.8e-143 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKNIKAKF_01646 2.8e-93 FNV0100 F NUDIX domain
MKNIKAKF_01648 1.5e-288 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
MKNIKAKF_01649 9.3e-305 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MKNIKAKF_01650 3.7e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MKNIKAKF_01653 3.9e-234 malY 4.4.1.8 E Aminotransferase, class I
MKNIKAKF_01654 2.5e-258 cpdA S Calcineurin-like phosphoesterase
MKNIKAKF_01655 1e-38 gcvR T Belongs to the UPF0237 family
MKNIKAKF_01656 2.1e-244 XK27_08635 S UPF0210 protein
MKNIKAKF_01657 4.3e-213 coiA 3.6.4.12 S Competence protein
MKNIKAKF_01658 2.3e-113 yjbH Q Thioredoxin
MKNIKAKF_01659 7.5e-106 yjbK S CYTH
MKNIKAKF_01660 1.3e-122 yjbM 2.7.6.5 S RelA SpoT domain protein
MKNIKAKF_01661 4.6e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKNIKAKF_01662 1.1e-169 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MKNIKAKF_01663 4.1e-203 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKNIKAKF_01664 1.5e-112 cutC P Participates in the control of copper homeostasis
MKNIKAKF_01665 2.1e-143 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKNIKAKF_01666 4.6e-199 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MKNIKAKF_01667 2.5e-62 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MKNIKAKF_01668 3.5e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKNIKAKF_01669 5.7e-191 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKNIKAKF_01670 5.7e-172 corA P CorA-like Mg2+ transporter protein
MKNIKAKF_01671 9.6e-155 rrmA 2.1.1.187 H Methyltransferase
MKNIKAKF_01672 9.4e-97 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKNIKAKF_01673 8.4e-72 WQ51_03320 S Protein of unknown function (DUF1149)
MKNIKAKF_01674 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MKNIKAKF_01675 9.4e-231 ymfF S Peptidase M16 inactive domain protein
MKNIKAKF_01676 3.4e-244 ymfH S Peptidase M16
MKNIKAKF_01677 2e-129 IQ Enoyl-(Acyl carrier protein) reductase
MKNIKAKF_01678 1.3e-109 ymfM S Helix-turn-helix domain
MKNIKAKF_01679 1.4e-104 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKNIKAKF_01680 4.2e-141 L Transposase
MKNIKAKF_01681 0.0 yknV V ABC transporter
MKNIKAKF_01682 1.3e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKNIKAKF_01683 1.9e-231 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKNIKAKF_01684 3.1e-107 engB D Necessary for normal cell division and for the maintenance of normal septation
MKNIKAKF_01685 7.8e-48 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MKNIKAKF_01686 1.3e-20
MKNIKAKF_01687 1.5e-259 arpJ P ABC transporter permease
MKNIKAKF_01688 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKNIKAKF_01689 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKNIKAKF_01690 0.0 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
MKNIKAKF_01691 6.7e-170 pfkB 2.7.1.11, 2.7.1.144, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MKNIKAKF_01692 6.6e-131 fruR K DeoR C terminal sensor domain
MKNIKAKF_01693 3.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKNIKAKF_01694 0.0 oatA I Acyltransferase
MKNIKAKF_01695 8.6e-184 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKNIKAKF_01696 1e-142 XK27_05435 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MKNIKAKF_01697 4.1e-48 yrvD S Lipopolysaccharide assembly protein A domain
MKNIKAKF_01698 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKNIKAKF_01699 3.5e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MKNIKAKF_01700 2.8e-94 M1-874 K Domain of unknown function (DUF1836)
MKNIKAKF_01701 4.7e-301 cpdB 3.1.3.6, 3.1.4.16 F 5'-nucleotidase, C-terminal domain
MKNIKAKF_01702 2.4e-135
MKNIKAKF_01703 2.5e-18 S Protein of unknown function (DUF2929)
MKNIKAKF_01704 0.0 dnaE 2.7.7.7 L DNA polymerase
MKNIKAKF_01705 7e-178 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKNIKAKF_01706 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MKNIKAKF_01707 1.5e-72 yeaL S Protein of unknown function (DUF441)
MKNIKAKF_01708 4.9e-162 cvfB S S1 domain
MKNIKAKF_01709 4.8e-165 xerD D recombinase XerD
MKNIKAKF_01710 2e-67 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKNIKAKF_01711 1.2e-124 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKNIKAKF_01712 5.5e-107 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKNIKAKF_01713 6.7e-136 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKNIKAKF_01714 2.6e-95 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKNIKAKF_01715 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MKNIKAKF_01716 6.8e-69 2.7.1.191 G PTS system fructose IIA component
MKNIKAKF_01717 0.0 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MKNIKAKF_01718 2.4e-153 G PTS system mannose/fructose/sorbose family IID component
MKNIKAKF_01719 2.8e-127 G PTS system sorbose-specific iic component
MKNIKAKF_01720 3e-84 2.7.1.191 G PTS system sorbose subfamily IIB component
MKNIKAKF_01721 3.1e-184 cytR 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MKNIKAKF_01722 1.9e-43 S Bacterial toxin of type II toxin-antitoxin system, YafQ
MKNIKAKF_01723 1.7e-151 S hydrolase
MKNIKAKF_01724 1e-262 npr 1.11.1.1 C NADH oxidase
MKNIKAKF_01725 5.3e-119 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MKNIKAKF_01726 1.5e-184 hrtB V ABC transporter permease
MKNIKAKF_01727 1.6e-85 ygfC K Bacterial regulatory proteins, tetR family
MKNIKAKF_01728 3.8e-113 3.2.1.17 M hydrolase, family 25
MKNIKAKF_01729 8.1e-12 S YvrJ protein family
MKNIKAKF_01731 1.4e-237 kgtP EGP Sugar (and other) transporter
MKNIKAKF_01732 1.6e-115 P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01733 2.9e-114 P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01734 5.1e-159 ET Bacterial periplasmic substrate-binding proteins
MKNIKAKF_01735 1.4e-128 E ABC transporter
MKNIKAKF_01736 4.6e-191 odh 1.5.1.28 C NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain
MKNIKAKF_01737 2.9e-218 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MKNIKAKF_01738 0.0 mtlF 2.7.1.197 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKNIKAKF_01739 6.7e-96 hxlB 4.1.2.43, 5.3.1.27 M SIS domain
MKNIKAKF_01740 7.7e-112 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
MKNIKAKF_01741 1.3e-134 fruR K DeoR C terminal sensor domain
MKNIKAKF_01742 1.4e-121 S Haloacid dehalogenase-like hydrolase
MKNIKAKF_01744 1e-271 G Glycosyl hydrolases family 32
MKNIKAKF_01745 1.2e-55
MKNIKAKF_01746 1.9e-147 levD G PTS system mannose/fructose/sorbose family IID component
MKNIKAKF_01747 1.6e-152 M PTS system sorbose-specific iic component
MKNIKAKF_01748 4.8e-90 2.7.1.191 G PTS system sorbose subfamily IIB component
MKNIKAKF_01749 5.3e-72 levA G PTS system fructose IIA component
MKNIKAKF_01750 0.0 K Sigma-54 interaction domain
MKNIKAKF_01752 8.8e-27
MKNIKAKF_01753 8.4e-57 hxlR K HxlR-like helix-turn-helix
MKNIKAKF_01754 4.5e-199 qor 1.1.1.1, 1.6.5.5 C Zinc-binding dehydrogenase
MKNIKAKF_01755 1.5e-163 morA2 S reductase
MKNIKAKF_01756 6.5e-75 K helix_turn_helix, mercury resistance
MKNIKAKF_01757 5.3e-248 E Amino acid permease
MKNIKAKF_01758 2.1e-221 S Amidohydrolase
MKNIKAKF_01759 1.2e-255 6.3.1.2 E Glutamine synthetase, catalytic domain
MKNIKAKF_01760 5.7e-143 puuD S peptidase C26
MKNIKAKF_01761 1.2e-94 H Protein of unknown function (DUF1698)
MKNIKAKF_01762 1.3e-19 H Protein of unknown function (DUF1698)
MKNIKAKF_01763 1.9e-144 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MKNIKAKF_01764 1.3e-195 V Beta-lactamase
MKNIKAKF_01765 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKNIKAKF_01766 1e-167 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MKNIKAKF_01767 9.6e-106 tag 3.2.2.20 L glycosylase
MKNIKAKF_01768 2.4e-107 K Transcriptional
MKNIKAKF_01769 4.5e-203 yceJ EGP Major facilitator Superfamily
MKNIKAKF_01770 3.6e-48 K Helix-turn-helix domain
MKNIKAKF_01771 8.5e-265 L Exonuclease
MKNIKAKF_01772 7.1e-53
MKNIKAKF_01774 1.1e-74 ohr O OsmC-like protein
MKNIKAKF_01775 1.4e-189 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MKNIKAKF_01776 5e-102 dhaL 2.7.1.121 S Dak2
MKNIKAKF_01777 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
MKNIKAKF_01778 1.5e-100 K Bacterial regulatory proteins, tetR family
MKNIKAKF_01779 1.7e-15
MKNIKAKF_01780 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MKNIKAKF_01781 7.9e-84
MKNIKAKF_01782 1.3e-198 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MKNIKAKF_01783 2.6e-155 metQ_4 P Belongs to the nlpA lipoprotein family
MKNIKAKF_01784 0.0 pip V domain protein
MKNIKAKF_01786 1.6e-302 yfiB V ABC transporter transmembrane region
MKNIKAKF_01787 7.5e-311 md2 V ABC transporter
MKNIKAKF_01788 7.2e-49 tnp2PF3 L Transposase DDE domain
MKNIKAKF_01789 1.2e-120 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MKNIKAKF_01790 1.7e-145 S Alpha/beta hydrolase of unknown function (DUF915)
MKNIKAKF_01791 7e-164 cylA V ABC transporter
MKNIKAKF_01792 1.2e-147 cylB V ABC-2 type transporter
MKNIKAKF_01793 1.7e-73 K LytTr DNA-binding domain
MKNIKAKF_01794 9.6e-44 S Protein of unknown function (DUF3021)
MKNIKAKF_01795 0.0 yjcE P Sodium proton antiporter
MKNIKAKF_01796 2.1e-241 S Protein of unknown function (DUF3800)
MKNIKAKF_01797 4.8e-249 yifK E Amino acid permease
MKNIKAKF_01798 1.7e-156 yeaE S Aldo/keto reductase family
MKNIKAKF_01799 5.1e-113 ylbE GM NAD(P)H-binding
MKNIKAKF_01800 1.9e-278 lsa S ABC transporter
MKNIKAKF_01801 1.6e-76 O OsmC-like protein
MKNIKAKF_01802 3e-67
MKNIKAKF_01803 4.6e-31 K 'Cold-shock' DNA-binding domain
MKNIKAKF_01804 4.6e-252 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MKNIKAKF_01805 3e-173 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
MKNIKAKF_01806 5.6e-267 yfnA E Amino Acid
MKNIKAKF_01807 3.6e-217 sstT U Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MKNIKAKF_01808 0.0 treB 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKNIKAKF_01809 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MKNIKAKF_01810 7.7e-129 treR K UTRA
MKNIKAKF_01811 6e-222 oxlT P Major Facilitator Superfamily
MKNIKAKF_01812 0.0 V ABC transporter
MKNIKAKF_01813 0.0 XK27_09600 V ABC transporter, ATP-binding protein
MKNIKAKF_01814 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKNIKAKF_01815 1.6e-165 metF 1.5.1.20 C Methylenetetrahydrofolate reductase
MKNIKAKF_01817 1.4e-121
MKNIKAKF_01818 4.1e-259 wcaJ M Bacterial sugar transferase
MKNIKAKF_01819 4.6e-174 cps2D 5.1.3.2 M RmlD substrate binding domain
MKNIKAKF_01820 7.4e-110 glnP P ABC transporter permease
MKNIKAKF_01821 4.6e-109 gluC P ABC transporter permease
MKNIKAKF_01822 3.8e-148 glnH ET ABC transporter substrate-binding protein
MKNIKAKF_01823 7.4e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKNIKAKF_01824 1.1e-173
MKNIKAKF_01826 6.1e-84 zur P Belongs to the Fur family
MKNIKAKF_01827 6.3e-09
MKNIKAKF_01828 1e-110 gmk2 2.7.4.8 F Guanylate kinase
MKNIKAKF_01829 1.9e-68 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
MKNIKAKF_01830 1.6e-126 spl M NlpC/P60 family
MKNIKAKF_01831 2.6e-244 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKNIKAKF_01832 3.3e-172 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKNIKAKF_01833 1e-54 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MKNIKAKF_01834 1.3e-173 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKNIKAKF_01835 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MKNIKAKF_01836 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKNIKAKF_01837 8.9e-286 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MKNIKAKF_01838 3.6e-200 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MKNIKAKF_01839 3.6e-197 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKNIKAKF_01840 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKNIKAKF_01841 1.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MKNIKAKF_01842 1.6e-99 ylcC 3.4.22.70 M Sortase family
MKNIKAKF_01843 1.8e-145 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNIKAKF_01844 0.0 fbp 3.1.3.11 G phosphatase activity
MKNIKAKF_01845 1.6e-151 S AAA-like domain
MKNIKAKF_01846 9.8e-49 S SIR2-like domain
MKNIKAKF_01847 6e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MKNIKAKF_01848 3e-178 coaA 2.7.1.33 F Pantothenic acid kinase
MKNIKAKF_01849 3.9e-12
MKNIKAKF_01850 8.7e-23
MKNIKAKF_01851 1.4e-275 pipD E Dipeptidase
MKNIKAKF_01852 8.5e-84 ykhA 3.1.2.20 I Thioesterase superfamily
MKNIKAKF_01853 0.0 helD 3.6.4.12 L DNA helicase
MKNIKAKF_01854 7.1e-21
MKNIKAKF_01855 0.0 yjbQ P TrkA C-terminal domain protein
MKNIKAKF_01856 1.1e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MKNIKAKF_01857 8e-79 yjhE S Phage tail protein
MKNIKAKF_01858 4.1e-240 mntH P H( )-stimulated, divalent metal cation uptake system
MKNIKAKF_01859 4.4e-188 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MKNIKAKF_01860 2.3e-127 pgm3 G Phosphoglycerate mutase family
MKNIKAKF_01861 0.0 V FtsX-like permease family
MKNIKAKF_01862 2.6e-135 cysA V ABC transporter, ATP-binding protein
MKNIKAKF_01863 0.0 E amino acid
MKNIKAKF_01864 3.4e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
MKNIKAKF_01865 2.4e-237 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKNIKAKF_01866 9e-152 nodB3 G Polysaccharide deacetylase
MKNIKAKF_01867 2.9e-274 S Glucosyl transferase GtrII
MKNIKAKF_01868 8e-223
MKNIKAKF_01869 1.3e-93
MKNIKAKF_01870 3.4e-173 3.1.4.46 M Peptidase_C39 like family
MKNIKAKF_01871 4.5e-117 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKNIKAKF_01872 1.3e-44 XK27_02675 K Acetyltransferase (GNAT) domain
MKNIKAKF_01873 1.2e-48
MKNIKAKF_01874 8.2e-19
MKNIKAKF_01875 3.8e-66 S Protein of unknown function (DUF1093)
MKNIKAKF_01876 5.3e-37
MKNIKAKF_01877 6.2e-111 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MKNIKAKF_01878 2.9e-87 XK27_03960 S Protein of unknown function (DUF3013)
MKNIKAKF_01879 1.1e-172 prmA J Ribosomal protein L11 methyltransferase
MKNIKAKF_01880 5.9e-132 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKNIKAKF_01881 1.3e-43
MKNIKAKF_01882 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKNIKAKF_01883 1.2e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKNIKAKF_01884 2.6e-117 3.1.3.18 J HAD-hyrolase-like
MKNIKAKF_01885 5.9e-244 lytH 3.5.1.28, 6.1.1.12 M N-acetylmuramoyl-L-alanine amidase
MKNIKAKF_01886 2.5e-73 FG adenosine 5'-monophosphoramidase activity
MKNIKAKF_01887 6.9e-156 V ABC transporter
MKNIKAKF_01888 5.8e-280
MKNIKAKF_01889 8.4e-131 K Helix-turn-helix
MKNIKAKF_01890 2.1e-76
MKNIKAKF_01891 4.1e-167 1.6.5.5 C nadph quinone reductase
MKNIKAKF_01892 1.7e-35 XK27_04345 3.6.1.1 C Inorganic pyrophosphatase
MKNIKAKF_01893 2.6e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MKNIKAKF_01894 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MKNIKAKF_01895 2.6e-82 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MKNIKAKF_01896 7.4e-169 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKNIKAKF_01897 1.3e-162 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKNIKAKF_01898 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKNIKAKF_01899 2.9e-21 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MKNIKAKF_01900 6.1e-68 yqeY S YqeY-like protein
MKNIKAKF_01902 2.9e-179 phoH T phosphate starvation-inducible protein PhoH
MKNIKAKF_01903 2e-82 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKNIKAKF_01904 3.1e-63 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MKNIKAKF_01905 8e-64 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
MKNIKAKF_01906 9.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKNIKAKF_01907 3.3e-141 recO L Involved in DNA repair and RecF pathway recombination
MKNIKAKF_01908 2.3e-53
MKNIKAKF_01909 3.2e-55
MKNIKAKF_01910 2.4e-12
MKNIKAKF_01912 9.3e-139 gntP EG Gluconate
MKNIKAKF_01913 2.4e-248 S O-antigen ligase like membrane protein
MKNIKAKF_01914 1.2e-151 S Glycosyl transferase family 2
MKNIKAKF_01915 8e-115 welB S Glycosyltransferase like family 2
MKNIKAKF_01916 8.8e-159 S Glycosyltransferase like family 2
MKNIKAKF_01917 3.9e-147 M Glycosyltransferase sugar-binding region containing DXD motif
MKNIKAKF_01918 0.0 M Glycosyl hydrolases family 25
MKNIKAKF_01919 5.4e-259 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
MKNIKAKF_01920 1.4e-161 S Glycosyltransferase like family 2
MKNIKAKF_01921 1.1e-197 S Protein conserved in bacteria
MKNIKAKF_01922 7.6e-58
MKNIKAKF_01923 2.2e-128 fhuC 3.6.3.35 P ABC transporter
MKNIKAKF_01924 3.3e-133 znuB U ABC 3 transport family
MKNIKAKF_01925 4.2e-166 T Calcineurin-like phosphoesterase superfamily domain
MKNIKAKF_01926 7.1e-161 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MKNIKAKF_01927 0.0 pepF E oligoendopeptidase F
MKNIKAKF_01928 7.4e-200 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKNIKAKF_01929 2.9e-249 brnQ U Component of the transport system for branched-chain amino acids
MKNIKAKF_01930 7e-71 T Sh3 type 3 domain protein
MKNIKAKF_01931 2.4e-133 glcR K DeoR C terminal sensor domain
MKNIKAKF_01932 2e-146 M Glycosyltransferase like family 2
MKNIKAKF_01933 3.3e-135 XK27_06755 S Protein of unknown function (DUF975)
MKNIKAKF_01934 1.4e-40
MKNIKAKF_01935 2.4e-107 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MKNIKAKF_01936 6e-174 draG O ADP-ribosylglycohydrolase
MKNIKAKF_01937 1.6e-293 S ABC transporter
MKNIKAKF_01938 1.6e-134 Q Methyltransferase domain
MKNIKAKF_01939 7.6e-177 sitA P Belongs to the bacterial solute-binding protein 9 family
MKNIKAKF_01940 3.6e-144 mtsB U ABC 3 transport family
MKNIKAKF_01941 2.2e-131 mntB 3.6.3.35 P AAA domain, putative AbiEii toxin, Type IV TA system
MKNIKAKF_01942 1.1e-275 aldA 1.2.1.21, 1.2.1.22 C Belongs to the aldehyde dehydrogenase family
MKNIKAKF_01943 3e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKNIKAKF_01944 5.9e-166 znuA P Belongs to the bacterial solute-binding protein 9 family
MKNIKAKF_01945 1.6e-117 GM NmrA-like family
MKNIKAKF_01946 8.3e-111 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
MKNIKAKF_01947 2.6e-70
MKNIKAKF_01948 2.4e-253 M domain protein
MKNIKAKF_01949 5.4e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
MKNIKAKF_01950 6.1e-20
MKNIKAKF_01951 3e-60
MKNIKAKF_01954 1.9e-51 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNIKAKF_01955 8.7e-69 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKNIKAKF_01957 2.3e-157 phnD P Phosphonate ABC transporter
MKNIKAKF_01958 7.5e-138 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MKNIKAKF_01959 1.7e-134 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01960 1.3e-145 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01961 1.8e-173 ssuA P NMT1-like family
MKNIKAKF_01962 6.8e-292 6.2.1.3, 6.2.1.8 IQ AMP-binding enzyme C-terminal domain
MKNIKAKF_01963 1.1e-167 yfiQ I Acyltransferase family
MKNIKAKF_01964 1.2e-115 ssuB P ATPases associated with a variety of cellular activities
MKNIKAKF_01965 1.2e-61 ssuC U Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01966 4.9e-66 ssuC U Binding-protein-dependent transport system inner membrane component
MKNIKAKF_01967 1.2e-121 S ABC-2 family transporter protein
MKNIKAKF_01968 5.4e-53 trxC O Belongs to the thioredoxin family
MKNIKAKF_01969 6.3e-137 thrE S Putative threonine/serine exporter
MKNIKAKF_01970 1.4e-75 S Threonine/Serine exporter, ThrE
MKNIKAKF_01971 1.4e-35 livJ E Receptor family ligand binding region
MKNIKAKF_01972 7.3e-141 livJ E Receptor family ligand binding region
MKNIKAKF_01973 6.9e-148 livH U Branched-chain amino acid transport system / permease component
MKNIKAKF_01974 4.6e-121 livM E Branched-chain amino acid transport system / permease component
MKNIKAKF_01975 8.1e-140 livG E Branched-chain amino acid ATP-binding cassette transporter
MKNIKAKF_01976 1.2e-11 livF E ABC transporter
MKNIKAKF_01977 2.3e-69 livF E ABC transporter
MKNIKAKF_01978 3.9e-67 ydeA S DJ-1/PfpI family
MKNIKAKF_01979 1.1e-22 mutT 3.6.1.55 F GDP-mannose mannosyl hydrolase activity
MKNIKAKF_01980 1.2e-39 yvdC S MazG nucleotide pyrophosphohydrolase domain
MKNIKAKF_01981 3.1e-167 S Alpha/beta hydrolase of unknown function (DUF915)
MKNIKAKF_01982 4.2e-234 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_01983 7.6e-118 XK27_12570 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKNIKAKF_01984 8.2e-117 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKNIKAKF_01985 6.8e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MKNIKAKF_01986 3.4e-129 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MKNIKAKF_01987 3.6e-152 M NlpC P60 family protein
MKNIKAKF_01990 1.4e-259 nox 1.6.3.4 C NADH oxidase
MKNIKAKF_01991 2.9e-89 sepS16B
MKNIKAKF_01992 8.1e-120
MKNIKAKF_01993 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MKNIKAKF_01994 6e-241 G Bacterial extracellular solute-binding protein
MKNIKAKF_01995 6e-86
MKNIKAKF_01996 0.0 strH 3.2.1.52 GH20 G Gram-positive signal peptide protein, YSIRK family
MKNIKAKF_01997 4.3e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
MKNIKAKF_01998 2.5e-200 gldA 1.1.1.1, 1.1.1.6 C dehydrogenase
MKNIKAKF_01999 1.1e-225 amd 3.5.1.47 E Peptidase family M20/M25/M40
MKNIKAKF_02000 3.8e-79 S Threonine/Serine exporter, ThrE
MKNIKAKF_02001 2.2e-134 thrE S Putative threonine/serine exporter
MKNIKAKF_02003 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKNIKAKF_02004 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKNIKAKF_02006 8.2e-129 jag S R3H domain protein
MKNIKAKF_02007 2.6e-136 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKNIKAKF_02008 6.1e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKNIKAKF_02009 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MKNIKAKF_02010 1.2e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKNIKAKF_02011 5.2e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKNIKAKF_02012 1.7e-31 yaaA S S4 domain protein YaaA
MKNIKAKF_02013 1.2e-202 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKNIKAKF_02014 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNIKAKF_02015 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKNIKAKF_02016 1.5e-124 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MKNIKAKF_02017 8.5e-75 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKNIKAKF_02018 5.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MKNIKAKF_02019 3.9e-62 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKNIKAKF_02020 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKNIKAKF_02021 4.7e-282 cydA 1.10.3.14 C Cytochrome bd terminal oxidase subunit I
MKNIKAKF_02022 3.9e-179 cydB 1.10.3.14 C Cytochrome bd terminal oxidase subunit II
MKNIKAKF_02023 2.4e-13
MKNIKAKF_02024 1.1e-62 yugI 5.3.1.9 J general stress protein
MKNIKAKF_02025 2.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKNIKAKF_02026 7.9e-185 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MKNIKAKF_02027 6.7e-87 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MKNIKAKF_02028 5.2e-116 dedA S SNARE-like domain protein
MKNIKAKF_02029 1.1e-112 S Protein of unknown function (DUF1461)
MKNIKAKF_02030 2.8e-145 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKNIKAKF_02031 6e-117 yutD S Protein of unknown function (DUF1027)
MKNIKAKF_02032 2.8e-265 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MKNIKAKF_02033 1.8e-115 S Calcineurin-like phosphoesterase
MKNIKAKF_02034 1.4e-114 yibF S overlaps another CDS with the same product name
MKNIKAKF_02035 9.8e-189 yibE S overlaps another CDS with the same product name
MKNIKAKF_02036 6.1e-54
MKNIKAKF_02037 1.1e-258 ugpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MKNIKAKF_02038 3.8e-273 pepV 3.5.1.18 E dipeptidase PepV
MKNIKAKF_02039 9.5e-138 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKNIKAKF_02040 1.1e-127 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
MKNIKAKF_02041 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M Penicillin binding protein transpeptidase domain
MKNIKAKF_02042 5.1e-179 ccpA K catabolite control protein A
MKNIKAKF_02043 6.3e-215 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKNIKAKF_02044 3e-90 niaR S 3H domain
MKNIKAKF_02045 2.7e-86 ytxH S YtxH-like protein
MKNIKAKF_02046 6e-12 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKNIKAKF_02047 2.1e-152 ykuT M mechanosensitive ion channel
MKNIKAKF_02048 3.5e-155 XK27_00890 S Domain of unknown function (DUF368)
MKNIKAKF_02050 2.2e-09
MKNIKAKF_02051 6.7e-223 L Belongs to the 'phage' integrase family
MKNIKAKF_02053 5.8e-28
MKNIKAKF_02054 4.6e-174 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MKNIKAKF_02055 4.4e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MKNIKAKF_02056 2.1e-168 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKNIKAKF_02057 2.9e-213 ydiN EGP Major Facilitator Superfamily
MKNIKAKF_02058 1.7e-162 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKNIKAKF_02059 1.7e-140 IQ Enoyl-(Acyl carrier protein) reductase
MKNIKAKF_02060 3e-159 G Xylose isomerase-like TIM barrel
MKNIKAKF_02061 4.8e-165 K Transcriptional regulator, LysR family
MKNIKAKF_02062 5.3e-76 S Protein of unknown function (DUF1440)
MKNIKAKF_02063 7.1e-275 ycaM E amino acid
MKNIKAKF_02064 0.0 pepN 3.4.11.2 E aminopeptidase
MKNIKAKF_02065 0.0 O Belongs to the peptidase S8 family
MKNIKAKF_02066 1.5e-143 O Belongs to the peptidase S8 family
MKNIKAKF_02067 4.9e-43 O Belongs to the peptidase S8 family
MKNIKAKF_02068 5.9e-149 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MKNIKAKF_02069 1.3e-88 S ECF-type riboflavin transporter, S component
MKNIKAKF_02070 2.9e-145 CcmA5 V ABC transporter
MKNIKAKF_02071 0.0
MKNIKAKF_02072 4.6e-177 yicL EG EamA-like transporter family
MKNIKAKF_02073 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MKNIKAKF_02074 5.1e-101 N WxL domain surface cell wall-binding
MKNIKAKF_02075 1.8e-57
MKNIKAKF_02076 1.1e-111 S WxL domain surface cell wall-binding
MKNIKAKF_02077 4.4e-198 XK27_00720 S Leucine-rich repeat (LRR) protein
MKNIKAKF_02078 1.5e-38
MKNIKAKF_02079 4e-171 S Cell surface protein
MKNIKAKF_02080 2.2e-117 S WxL domain surface cell wall-binding
MKNIKAKF_02081 4.8e-252 brnQ U Component of the transport system for branched-chain amino acids
MKNIKAKF_02082 7.2e-31
MKNIKAKF_02083 5.3e-122 tcyB E ABC transporter
MKNIKAKF_02084 3.9e-145 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MKNIKAKF_02085 5.1e-212 metC 4.4.1.8 E cystathionine
MKNIKAKF_02086 7.3e-183 CP_0155 3.5.1.28 M Glycosyl hydrolases family 25
MKNIKAKF_02087 1.2e-152 licT K CAT RNA binding domain
MKNIKAKF_02088 2e-289 cydC V ABC transporter transmembrane region
MKNIKAKF_02089 6.5e-87 cydD CO ABC transporter transmembrane region
MKNIKAKF_02090 1.5e-217 cydD CO ABC transporter transmembrane region
MKNIKAKF_02091 1.2e-73 S NusG domain II
MKNIKAKF_02092 1e-156 M Peptidoglycan-binding domain 1 protein
MKNIKAKF_02093 4.3e-141
MKNIKAKF_02094 1.5e-214 ywhK S Membrane
MKNIKAKF_02095 7.1e-62 S Protein of unknown function (DUF1093)
MKNIKAKF_02096 7.1e-50 yvlA
MKNIKAKF_02097 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKNIKAKF_02098 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MKNIKAKF_02099 1.3e-182 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MKNIKAKF_02100 6.8e-278 cydA 1.10.3.14 C ubiquinol oxidase
MKNIKAKF_02102 3.1e-237 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MKNIKAKF_02103 1.4e-189 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MKNIKAKF_02104 8.6e-40
MKNIKAKF_02105 1.4e-86
MKNIKAKF_02106 8e-24
MKNIKAKF_02107 5e-165 yicL EG EamA-like transporter family
MKNIKAKF_02108 3.3e-112 tag 3.2.2.20 L glycosylase
MKNIKAKF_02109 5e-78 usp5 T universal stress protein
MKNIKAKF_02110 3.2e-96
MKNIKAKF_02111 5.5e-288 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKNIKAKF_02112 4e-57 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MKNIKAKF_02113 4.5e-208 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_02114 2.6e-49 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_02115 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GKT Mga helix-turn-helix domain
MKNIKAKF_02116 7e-104 L Resolvase, N terminal domain
MKNIKAKF_02117 0.0 yvcC M Cna protein B-type domain
MKNIKAKF_02118 8.8e-125 M domain protein
MKNIKAKF_02119 2.8e-185 M LPXTG cell wall anchor motif
MKNIKAKF_02120 9.5e-200 3.4.22.70 M Sortase family
MKNIKAKF_02121 1.6e-115 XK27_12140 V ATPases associated with a variety of cellular activities
MKNIKAKF_02122 8.2e-296 S Psort location CytoplasmicMembrane, score
MKNIKAKF_02123 2.7e-126 K Transcriptional regulatory protein, C terminal
MKNIKAKF_02124 1.3e-194 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
MKNIKAKF_02125 7.7e-139 V ATPases associated with a variety of cellular activities
MKNIKAKF_02126 2.4e-209
MKNIKAKF_02127 1.5e-91
MKNIKAKF_02128 2.4e-164 O Belongs to the peptidase S8 family
MKNIKAKF_02129 3e-170 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKNIKAKF_02130 6.6e-181 D Alpha beta
MKNIKAKF_02131 2.4e-186 lipA I Carboxylesterase family
MKNIKAKF_02132 5.6e-206 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MKNIKAKF_02133 1.1e-77 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKNIKAKF_02134 0.0 mtlR K Mga helix-turn-helix domain
MKNIKAKF_02135 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_02136 7.2e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKNIKAKF_02137 3.3e-149 S haloacid dehalogenase-like hydrolase
MKNIKAKF_02138 3.1e-43
MKNIKAKF_02139 5.2e-10
MKNIKAKF_02140 1.8e-151 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MKNIKAKF_02141 7.1e-124 V ABC transporter
MKNIKAKF_02142 7.5e-206 bacI V MacB-like periplasmic core domain
MKNIKAKF_02143 0.0 M Leucine rich repeats (6 copies)
MKNIKAKF_02144 8.6e-28 M Leucine rich repeats (6 copies)
MKNIKAKF_02145 1.5e-69 3.4.22.70 M Sortase family
MKNIKAKF_02146 2.9e-229 ywhK S Membrane
MKNIKAKF_02147 3.1e-42
MKNIKAKF_02149 1.1e-147 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKNIKAKF_02150 1.2e-201 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKNIKAKF_02151 1.7e-224 pimH EGP Major facilitator Superfamily
MKNIKAKF_02152 1.3e-38
MKNIKAKF_02153 9.6e-32
MKNIKAKF_02154 7e-08
MKNIKAKF_02155 1e-09 yhjA K CsbD-like
MKNIKAKF_02156 4.6e-205 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MKNIKAKF_02157 7.2e-46
MKNIKAKF_02158 6e-205 ltrA S Bacterial low temperature requirement A protein (LtrA)
MKNIKAKF_02159 7.7e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKNIKAKF_02160 2.6e-92 ccpN K Domain in cystathionine beta-synthase and other proteins.
MKNIKAKF_02161 0.0 ppdK 2.7.9.1 G Belongs to the PEP-utilizing enzyme family
MKNIKAKF_02162 6.8e-116 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MKNIKAKF_02163 1.5e-98 dps P Belongs to the Dps family
MKNIKAKF_02164 5.6e-33 copZ P Heavy-metal-associated domain
MKNIKAKF_02165 0.0 3.6.3.3, 3.6.3.5 P P-type ATPase
MKNIKAKF_02166 6.7e-23 ypbD S CAAX protease self-immunity
MKNIKAKF_02167 7.2e-215 opuCA 2.7.7.7 E ABC transporter, ATP-binding protein
MKNIKAKF_02168 1e-105 opuCB E ABC transporter permease
MKNIKAKF_02169 3.3e-172 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKNIKAKF_02170 3.3e-110 opuCD P Binding-protein-dependent transport system inner membrane component
MKNIKAKF_02172 7.4e-109 K Tetracycline repressor, C-terminal all-alpha domain
MKNIKAKF_02173 0.0 ydgH S MMPL family
MKNIKAKF_02174 1.6e-49 K TRANSCRIPTIONal
MKNIKAKF_02175 3.1e-179 EGP Major facilitator Superfamily
MKNIKAKF_02176 7.7e-46 EGP Major facilitator Superfamily
MKNIKAKF_02177 1.6e-152 V ABC-type multidrug transport system, ATPase and permease components
MKNIKAKF_02181 1.5e-180 S Aldo keto reductase
MKNIKAKF_02182 2.2e-118 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKNIKAKF_02183 1.9e-217 yqiG C Oxidoreductase
MKNIKAKF_02184 1.1e-253 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKNIKAKF_02185 1.5e-135
MKNIKAKF_02186 4.5e-20
MKNIKAKF_02187 6.5e-261 mntH P H( )-stimulated, divalent metal cation uptake system
MKNIKAKF_02188 0.0 pacL P P-type ATPase
MKNIKAKF_02189 7.5e-56
MKNIKAKF_02190 1.7e-238 EGP Major Facilitator Superfamily
MKNIKAKF_02191 0.0 mco Q Multicopper oxidase
MKNIKAKF_02192 3.6e-25
MKNIKAKF_02193 6.4e-111 2.5.1.105 P Cation efflux family
MKNIKAKF_02194 2.1e-52 czrA K Transcriptional regulator, ArsR family
MKNIKAKF_02195 1.3e-48
MKNIKAKF_02196 7.4e-57 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKNIKAKF_02197 1.5e-16
MKNIKAKF_02198 6.7e-139 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKNIKAKF_02199 2e-166 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKNIKAKF_02200 2.8e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKNIKAKF_02201 2.1e-70 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKNIKAKF_02202 1.2e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKNIKAKF_02203 1.5e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
MKNIKAKF_02204 7.8e-188 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKNIKAKF_02205 3.7e-196 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKNIKAKF_02206 2.5e-62
MKNIKAKF_02207 4.5e-73 3.6.1.55 L NUDIX domain
MKNIKAKF_02208 3.4e-147 EG EamA-like transporter family
MKNIKAKF_02209 7e-178 V ABC transporter transmembrane region
MKNIKAKF_02210 1.7e-32 S Phospholipase A2
MKNIKAKF_02211 2.6e-52 ybjQ S Belongs to the UPF0145 family
MKNIKAKF_02212 4.8e-160 3.5.1.10 C nadph quinone reductase
MKNIKAKF_02213 2.8e-246 amt P ammonium transporter
MKNIKAKF_02214 2.4e-178 yfeX P Peroxidase
MKNIKAKF_02215 2e-118 yhiD S MgtC family
MKNIKAKF_02216 2.1e-114 F DNA RNA non-specific endonuclease
MKNIKAKF_02217 0.0 ybiT S ABC transporter, ATP-binding protein
MKNIKAKF_02218 0.0 mutS L ATPase domain of DNA mismatch repair MUTS family
MKNIKAKF_02219 1e-110 ung2 3.2.2.27 L Uracil-DNA glycosylase
MKNIKAKF_02220 2.6e-129 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKNIKAKF_02221 6.7e-302 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MKNIKAKF_02222 2.1e-293 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKNIKAKF_02223 2.3e-86 epsG 2.4.1.293 GT2 M Glycosyltransferase like family 2
MKNIKAKF_02225 0.0 sca1 G Belongs to the glycosyl hydrolase 31 family
MKNIKAKF_02226 9.9e-146 3.5.2.6 V Beta-lactamase enzyme family
MKNIKAKF_02227 8e-191 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
MKNIKAKF_02228 7.4e-194 blaA6 V Beta-lactamase
MKNIKAKF_02229 1.6e-155 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKNIKAKF_02230 8.9e-162 ybbH_2 K Helix-turn-helix domain, rpiR family
MKNIKAKF_02231 3.1e-81 2.7.1.191 G PTS system sorbose subfamily IIB component
MKNIKAKF_02232 8.3e-151 G PTS system mannose/fructose/sorbose family IID component
MKNIKAKF_02233 2e-128 G PTS system sorbose-specific iic component
MKNIKAKF_02234 1.5e-200 S endonuclease exonuclease phosphatase family protein
MKNIKAKF_02235 1.7e-173 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MKNIKAKF_02236 3.1e-54
MKNIKAKF_02237 3.4e-242 mntH P H( )-stimulated, divalent metal cation uptake system
MKNIKAKF_02238 1.2e-112 K Bacterial regulatory proteins, tetR family
MKNIKAKF_02239 9.1e-164 corA P CorA-like Mg2+ transporter protein
MKNIKAKF_02240 2.6e-101 S Protein of unknown function (DUF1211)
MKNIKAKF_02241 6.1e-124 S membrane transporter protein
MKNIKAKF_02242 3e-48
MKNIKAKF_02243 5.9e-154 supH G Sucrose-6F-phosphate phosphohydrolase
MKNIKAKF_02244 5.4e-98 K transcriptional regulator
MKNIKAKF_02245 2.8e-128 macB V ABC transporter, ATP-binding protein
MKNIKAKF_02246 0.0 ylbB V ABC transporter permease
MKNIKAKF_02247 4.7e-110 usp 3.5.1.28 CBM50 D CHAP domain
MKNIKAKF_02250 1.1e-104 S Protein of unknown function (DUF1211)
MKNIKAKF_02253 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MKNIKAKF_02254 7.9e-223 mesE M Transport protein ComB
MKNIKAKF_02255 1.4e-59
MKNIKAKF_02257 1.5e-250 yjjP S Putative threonine/serine exporter
MKNIKAKF_02258 2.8e-45 spiA K TRANSCRIPTIONal
MKNIKAKF_02259 3.6e-45 S Enterocin A Immunity
MKNIKAKF_02260 5.4e-46 S Enterocin A Immunity
MKNIKAKF_02261 3.8e-137
MKNIKAKF_02262 6.6e-65
MKNIKAKF_02263 2.2e-54 K Transcriptional regulator PadR-like family
MKNIKAKF_02264 8.8e-113 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_02265 1e-206 MA20_36090 S Protein of unknown function (DUF2974)
MKNIKAKF_02266 4e-231 N Uncharacterized conserved protein (DUF2075)
MKNIKAKF_02267 4.3e-103
MKNIKAKF_02268 2e-34
MKNIKAKF_02269 4e-80 perR P Belongs to the Fur family
MKNIKAKF_02270 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKNIKAKF_02271 1.9e-43 ykuJ S Protein of unknown function (DUF1797)
MKNIKAKF_02272 7.7e-219 patA 2.6.1.1 E Aminotransferase
MKNIKAKF_02274 1.9e-165 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKNIKAKF_02275 1.2e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
MKNIKAKF_02276 1.2e-230 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MKNIKAKF_02278 3.8e-283 ybeC E amino acid
MKNIKAKF_02279 2.1e-94 sigH K DNA-templated transcription, initiation
MKNIKAKF_02304 1.1e-178 rapL 4.3.1.12 E Ornithine cyclodeaminase/mu-crystallin family
MKNIKAKF_02305 5.8e-147 S Sulfite exporter TauE/SafE
MKNIKAKF_02306 2.9e-156 K Sugar-specific transcriptional regulator TrmB
MKNIKAKF_02307 1.3e-114 6.3.4.4 S Zeta toxin
MKNIKAKF_02308 7.5e-163 4.1.2.13 G Fructose-bisphosphate aldolase class-II
MKNIKAKF_02309 3.6e-70
MKNIKAKF_02310 9.3e-210 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MKNIKAKF_02311 5.8e-49 ptxB 2.7.1.194, 2.7.1.200, 2.7.1.204 G PTS system, Lactose/Cellobiose specific IIB subunit
MKNIKAKF_02312 1.2e-198 GKT transcriptional antiterminator
MKNIKAKF_02314 5.8e-267 frdC 1.3.5.4 C HI0933-like protein
MKNIKAKF_02315 4.4e-52
MKNIKAKF_02316 1.3e-61
MKNIKAKF_02317 1.2e-272 bglP 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKNIKAKF_02318 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKNIKAKF_02319 1.5e-95 yxaF K Bacterial regulatory proteins, tetR family
MKNIKAKF_02320 4.7e-247 lmrB EGP Major facilitator Superfamily
MKNIKAKF_02321 1.1e-258 gor 1.8.1.7 C Glutathione reductase
MKNIKAKF_02322 1.5e-280 pipD E Dipeptidase
MKNIKAKF_02323 4e-62 S Coenzyme PQQ synthesis protein D (PqqD)
MKNIKAKF_02324 1.4e-294 S OPT oligopeptide transporter protein
MKNIKAKF_02325 2e-186 tdcB 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MKNIKAKF_02326 5.8e-200 ald 1.4.1.1 C Belongs to the AlaDH PNT family
MKNIKAKF_02327 5.5e-49 tnp2PF3 L Transposase DDE domain
MKNIKAKF_02329 2.2e-194 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKNIKAKF_02330 1.1e-292 clcA P chloride
MKNIKAKF_02331 2.7e-27
MKNIKAKF_02332 5.3e-111 S Putative esterase
MKNIKAKF_02333 7.3e-219 2.7.1.211 G phosphotransferase system
MKNIKAKF_02334 1.7e-79 4.2.1.126 S Bacterial protein of unknown function (DUF871)
MKNIKAKF_02335 1.3e-93 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKNIKAKF_02336 3.6e-48 yleF K Helix-turn-helix domain, rpiR family
MKNIKAKF_02337 5.1e-31 treB G phosphotransferase system
MKNIKAKF_02338 1.4e-49 S Protein of unknown function (DUF1093)
MKNIKAKF_02340 7.3e-72 ybfG M peptidoglycan-binding domain-containing protein
MKNIKAKF_02342 7.7e-79
MKNIKAKF_02345 1.5e-132
MKNIKAKF_02346 2.1e-70
MKNIKAKF_02348 9.3e-155 dnaC L IstB-like ATP binding protein
MKNIKAKF_02349 2.5e-74 L Helix-turn-helix domain
MKNIKAKF_02350 6e-51 L Helix-turn-helix domain
MKNIKAKF_02356 7.8e-44 S Domain of unknown function (DUF1883)
MKNIKAKF_02358 1.1e-138 S ORF6N domain
MKNIKAKF_02359 7.2e-155 ps305 S Protein of unknown function (Hypoth_ymh)
MKNIKAKF_02362 7.5e-61 ps115 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_02363 6e-20 E Zn peptidase
MKNIKAKF_02364 7.8e-134
MKNIKAKF_02367 8.9e-147 IQ reductase
MKNIKAKF_02368 1e-111 I ABC-2 family transporter protein
MKNIKAKF_02369 1.1e-161 CcmA V ABC transporter
MKNIKAKF_02370 3.6e-64 K helix_turn_helix gluconate operon transcriptional repressor
MKNIKAKF_02371 8.9e-221 ysdA CP ABC-2 family transporter protein
MKNIKAKF_02372 3.7e-165 natA S abc transporter atp-binding protein
MKNIKAKF_02373 2.9e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKNIKAKF_02374 5.1e-176 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKNIKAKF_02375 2.8e-160 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MKNIKAKF_02376 1.3e-204 S Calcineurin-like phosphoesterase
MKNIKAKF_02378 1.3e-117 mprF 2.3.2.3 M lysyltransferase activity
MKNIKAKF_02379 1.5e-223 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKNIKAKF_02380 4.7e-304 frvR K Mga helix-turn-helix domain
MKNIKAKF_02381 5.9e-296 frvR K Mga helix-turn-helix domain
MKNIKAKF_02382 1.3e-263 lysP E amino acid
MKNIKAKF_02384 9e-130 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MKNIKAKF_02385 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MKNIKAKF_02386 2e-97
MKNIKAKF_02387 2.3e-98 2.3.1.128 J Acetyltransferase (GNAT) domain
MKNIKAKF_02388 3.3e-88 ywrF S Flavin reductase like domain
MKNIKAKF_02389 2.1e-166 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MKNIKAKF_02390 2.7e-45
MKNIKAKF_02391 5.7e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKNIKAKF_02392 3.1e-24
MKNIKAKF_02393 3.2e-209 yubA S AI-2E family transporter
MKNIKAKF_02394 7.5e-80
MKNIKAKF_02395 3.5e-53
MKNIKAKF_02397 3.1e-192 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MKNIKAKF_02398 8.7e-42
MKNIKAKF_02399 1.2e-41 ygbF S Sugar efflux transporter for intercellular exchange
MKNIKAKF_02400 1.5e-58 K Transcriptional regulator PadR-like family
MKNIKAKF_02401 2.8e-188 K DNA-binding helix-turn-helix protein
MKNIKAKF_02404 1.3e-22 S Bacteriophage abortive infection AbiH
MKNIKAKF_02405 4.1e-59
MKNIKAKF_02406 0.0 pepF E Oligopeptidase F
MKNIKAKF_02407 3.2e-49 V ABC transporter transmembrane region
MKNIKAKF_02408 9.3e-226 V ABC transporter transmembrane region
MKNIKAKF_02409 1.7e-171 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_02410 5.5e-86 C FMN binding
MKNIKAKF_02411 1.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKNIKAKF_02412 3.2e-170 mleP S Sodium Bile acid symporter family
MKNIKAKF_02413 0.0 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MKNIKAKF_02414 1.5e-155 mleR K LysR family
MKNIKAKF_02415 9.5e-135 3.6.1.13, 3.6.1.55 F NUDIX domain
MKNIKAKF_02416 9.9e-108 pncA Q Isochorismatase family
MKNIKAKF_02417 2.4e-267 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKNIKAKF_02418 1.5e-211 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
MKNIKAKF_02419 1.9e-64 ugpA P ABC-type sugar transport systems, permease components
MKNIKAKF_02420 3.3e-80 ugpA P ABC-type sugar transport systems, permease components
MKNIKAKF_02421 3.4e-149 ugpE G ABC transporter permease
MKNIKAKF_02422 1.7e-149 ugpB G Bacterial extracellular solute-binding protein
MKNIKAKF_02423 1.8e-135 mga K M protein trans-acting positive regulator
MKNIKAKF_02424 1.2e-86
MKNIKAKF_02425 0.0 S Bacterial membrane protein YfhO
MKNIKAKF_02426 4.1e-150 licT2 K CAT RNA binding domain
MKNIKAKF_02427 0.0 bglH 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system
MKNIKAKF_02428 2.2e-284 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKNIKAKF_02429 1.1e-256 ykgC 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MKNIKAKF_02430 1.9e-247 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
MKNIKAKF_02431 1.5e-52
MKNIKAKF_02432 2.5e-65
MKNIKAKF_02433 5.7e-172 hprA 1.1.1.29 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKNIKAKF_02434 2.5e-190 L Psort location Cytoplasmic, score
MKNIKAKF_02435 6.2e-34
MKNIKAKF_02436 4.2e-49 tnp2PF3 L Transposase DDE domain
MKNIKAKF_02437 2.6e-24
MKNIKAKF_02438 2.8e-102
MKNIKAKF_02439 4.7e-73 K helix_turn_helix multiple antibiotic resistance protein
MKNIKAKF_02440 6e-239 ydiC1 EGP Major facilitator Superfamily
MKNIKAKF_02441 0.0 pbpC M NTF2-like N-terminal transpeptidase domain
MKNIKAKF_02442 6.9e-35 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MKNIKAKF_02443 3.1e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKNIKAKF_02444 1.8e-44 S Phage gp6-like head-tail connector protein
MKNIKAKF_02445 5.7e-43 S Phage capsid family
MKNIKAKF_02446 3.8e-177 S Phage capsid family
MKNIKAKF_02447 2.4e-44 S Phage portal protein
MKNIKAKF_02448 4.4e-141 S Phage portal protein
MKNIKAKF_02450 1e-103 sip L Belongs to the 'phage' integrase family
MKNIKAKF_02451 3.8e-125 lctO C IMP dehydrogenase / GMP reductase domain
MKNIKAKF_02452 2.6e-65 nrp 1.20.4.1 P ArsC family
MKNIKAKF_02453 0.0 clpL O associated with various cellular activities
MKNIKAKF_02454 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
MKNIKAKF_02455 5.4e-156 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKNIKAKF_02456 3.2e-115 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MKNIKAKF_02457 4.2e-49 tnp2PF3 L Transposase DDE domain
MKNIKAKF_02458 1.6e-155 glcU U sugar transport
MKNIKAKF_02459 2.4e-22 J Putative rRNA methylase
MKNIKAKF_02460 1.9e-35 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
MKNIKAKF_02461 7.3e-49 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKNIKAKF_02462 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MKNIKAKF_02463 3.5e-185 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MKNIKAKF_02464 2.7e-38 rafA 3.2.1.22 G alpha-galactosidase
MKNIKAKF_02465 3.4e-162 repA S Replication initiator protein A
MKNIKAKF_02466 9.6e-43 relB L Addiction module antitoxin, RelB DinJ family
MKNIKAKF_02467 5.9e-28
MKNIKAKF_02468 4.1e-116 S protein conserved in bacteria
MKNIKAKF_02469 1.7e-39
MKNIKAKF_02470 5.3e-22
MKNIKAKF_02471 0.0 L MobA MobL family protein
MKNIKAKF_02472 2.4e-90 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MKNIKAKF_02473 0.0 kup P Transport of potassium into the cell
MKNIKAKF_02474 8.7e-167 V ATPases associated with a variety of cellular activities
MKNIKAKF_02475 1.9e-217 S ABC-2 family transporter protein
MKNIKAKF_02476 1.7e-196
MKNIKAKF_02477 2.3e-51 lacF 2.7.1.196, 2.7.1.205, 2.7.1.207 G PTS system, Lactose/Cellobiose specific IIA subunit
MKNIKAKF_02478 8e-287 lacG 3.2.1.85 G Belongs to the glycosyl hydrolase 1 family
MKNIKAKF_02479 0.0 celB 2.7.1.196, 2.7.1.205, 2.7.1.207 G Phosphotransferase system, EIIC
MKNIKAKF_02480 1.4e-156 lacT K PRD domain
MKNIKAKF_02481 1.3e-108
MKNIKAKF_02484 0.0
MKNIKAKF_02485 3.5e-70 adhR K helix_turn_helix, mercury resistance
MKNIKAKF_02486 7.1e-87 bioY S BioY family
MKNIKAKF_02487 1.4e-62
MKNIKAKF_02488 3.1e-225 queG 1.17.99.6 C Domain of unknown function (DUF1730)
MKNIKAKF_02489 4.3e-144 ptp3 3.1.3.48 T Tyrosine phosphatase family
MKNIKAKF_02490 1.8e-55 K Helix-turn-helix XRE-family like proteins
MKNIKAKF_02492 0.0 asnB 6.3.5.4 E Asparagine synthase
MKNIKAKF_02493 3e-71 FG Scavenger mRNA decapping enzyme C-term binding
MKNIKAKF_02494 2.3e-125 WQ51_05710 S Mitochondrial biogenesis AIM24
MKNIKAKF_02496 1.2e-62
MKNIKAKF_02497 9.9e-62 S MucBP domain
MKNIKAKF_02498 2.1e-102 ywnB S NAD(P)H-binding
MKNIKAKF_02501 1.1e-122 E lipolytic protein G-D-S-L family
MKNIKAKF_02502 9.4e-70 feoA P FeoA
MKNIKAKF_02503 9.5e-22 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MKNIKAKF_02504 2.1e-48 tnp2PF3 L Transposase DDE domain
MKNIKAKF_02505 5e-134 S ABC-2 family transporter protein
MKNIKAKF_02506 1.4e-133 S ABC transporter
MKNIKAKF_02507 3.9e-26 S Protein of unknown function (DUF2785)
MKNIKAKF_02508 7.7e-100
MKNIKAKF_02509 1.6e-52
MKNIKAKF_02510 2.3e-102 yncA 2.3.1.79 S Maltose acetyltransferase
MKNIKAKF_02511 3.8e-54 S Enterocin A Immunity
MKNIKAKF_02513 2.9e-54
MKNIKAKF_02515 1e-142 S CAAX protease self-immunity
MKNIKAKF_02517 1.3e-284 pipD E Dipeptidase
MKNIKAKF_02518 3.1e-105 S Membrane
MKNIKAKF_02519 6.2e-103
MKNIKAKF_02520 9.8e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKNIKAKF_02521 1.7e-176 proV E ABC transporter, ATP-binding protein
MKNIKAKF_02522 9.2e-253 gshR 1.8.1.7 C Glutathione reductase
MKNIKAKF_02523 4.8e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MKNIKAKF_02524 3.5e-219 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MKNIKAKF_02525 1.1e-169 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MKNIKAKF_02526 1.1e-23 L 4.5 Transposon and IS
MKNIKAKF_02529 5.6e-128 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MKNIKAKF_02530 1.2e-256 repE K Primase C terminal 1 (PriCT-1)
MKNIKAKF_02531 2.6e-81
MKNIKAKF_02532 5.4e-31
MKNIKAKF_02533 5.6e-104
MKNIKAKF_02534 1e-42 ydzE EG EamA-like transporter family
MKNIKAKF_02535 2e-41 S Phospholipase A2
MKNIKAKF_02537 4e-68 K Tetracyclin repressor, C-terminal all-alpha domain
MKNIKAKF_02538 7.7e-60 V ABC-2 type transporter
MKNIKAKF_02539 1.5e-10 V ABC-2 type transporter
MKNIKAKF_02540 1.4e-58 P ABC-2 family transporter protein
MKNIKAKF_02541 2.2e-75 K Copper transport repressor CopY TcrY
MKNIKAKF_02542 0.0 copB 3.6.3.4 P E1-E2 ATPase
MKNIKAKF_02543 3e-38 mdt(A) EGP Major facilitator Superfamily
MKNIKAKF_02544 0.0 O Belongs to the peptidase S8 family
MKNIKAKF_02545 3.4e-95 O Belongs to the peptidase S8 family
MKNIKAKF_02546 9.2e-270 nagZ 3.2.1.52 G Glycosyl hydrolase family 3 N terminal domain
MKNIKAKF_02548 2.3e-74 repA L Initiator Replication protein
MKNIKAKF_02549 4e-20 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
MKNIKAKF_02550 6.4e-69 S COG NOG38524 non supervised orthologous group
MKNIKAKF_02551 7.9e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKNIKAKF_02552 5.7e-61 yeaO S Protein of unknown function, DUF488
MKNIKAKF_02553 1.3e-173 corA P CorA-like Mg2+ transporter protein
MKNIKAKF_02554 1.7e-17 pspF K Bacterial regulatory protein, Fis family
MKNIKAKF_02555 3.4e-62 qnr S Pentapeptide repeats (9 copies)
MKNIKAKF_02556 1e-29
MKNIKAKF_02557 1.6e-189 ybiR P Citrate transporter
MKNIKAKF_02558 1.3e-35 S Protein of unknown function (DUF1722)
MKNIKAKF_02559 1.2e-30 L Uncharacterised protein family (UPF0236)
MKNIKAKF_02560 2.7e-40 L Psort location Cytoplasmic, score 8.96
MKNIKAKF_02563 6.3e-159
MKNIKAKF_02564 1.4e-49
MKNIKAKF_02565 3.1e-56
MKNIKAKF_02566 1e-12 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
MKNIKAKF_02567 0.0 dld 1.1.5.12 C D-lactate dehydrogenase, membrane binding
MKNIKAKF_02568 1.4e-48 M COG0463 Glycosyltransferases involved in cell wall biogenesis
MKNIKAKF_02569 1.8e-66 M Glycosyl transferases group 1
MKNIKAKF_02570 1.4e-98 GM NAD(P)H-binding
MKNIKAKF_02571 1.8e-151 2.3.1.128 K Acetyltransferase (GNAT) domain
MKNIKAKF_02572 7.4e-88 K Acetyltransferase (GNAT) domain
MKNIKAKF_02573 3e-116 K CAT RNA binding domain
MKNIKAKF_02574 1.3e-75 S Metallo-beta-lactamase superfamily
MKNIKAKF_02575 4e-27
MKNIKAKF_02576 1.8e-62 L IS66 Orf2 like protein
MKNIKAKF_02577 2.7e-293 L Transposase IS66 family
MKNIKAKF_02579 2.2e-14 ytgB S Transglycosylase associated protein
MKNIKAKF_02580 2.9e-16
MKNIKAKF_02582 1.4e-27 L Transposase DDE domain
MKNIKAKF_02584 3e-44 L Initiator Replication protein
MKNIKAKF_02585 4.9e-38 L Transposase and inactivated derivatives
MKNIKAKF_02586 3.1e-248 G MFS/sugar transport protein
MKNIKAKF_02589 6.1e-35
MKNIKAKF_02591 1.1e-26 rom S Rop protein
MKNIKAKF_02592 9.3e-35 S Bacterial mobilisation protein (MobC)
MKNIKAKF_02593 1.7e-215 L Transposase DDE domain group 1
MKNIKAKF_02595 2.8e-72 cpsE M Bacterial sugar transferase
MKNIKAKF_02596 4.5e-65 L Transposase IS200 like
MKNIKAKF_02597 2.6e-115 L Resolvase, N terminal domain
MKNIKAKF_02598 3.2e-46 ligA 6.5.1.2 L BRCA1 C Terminus (BRCT) domain
MKNIKAKF_02599 6.7e-20 S Bacteriophage abortive infection AbiH
MKNIKAKF_02600 9.3e-70 yqeB S Pyrimidine dimer DNA glycosylase
MKNIKAKF_02601 1.7e-69 pdxH S Pyridoxamine 5'-phosphate oxidase
MKNIKAKF_02602 3.2e-71 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKNIKAKF_02603 6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MKNIKAKF_02604 7.1e-59 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MKNIKAKF_02605 6e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MKNIKAKF_02606 6.4e-122 S MobA/MobL family
MKNIKAKF_02607 5.9e-87 L Transposase and inactivated derivatives IS30 family
MKNIKAKF_02608 1.1e-18 S Bacteriophage abortive infection AbiH

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)