ORF_ID e_value Gene_name EC_number CAZy COGs Description
KOILJNNC_00001 4e-89 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00002 4.2e-294 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00003 3.4e-39 S COG NOG14552 non supervised orthologous group
KOILJNNC_00006 2e-08
KOILJNNC_00014 1.9e-17 Q PFAM Collagen triple helix
KOILJNNC_00015 1.6e-91 M Glycosyltransferase like family
KOILJNNC_00016 4.4e-121 H Methionine biosynthesis protein MetW
KOILJNNC_00017 1.6e-194 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_00018 7.1e-216 sumf2 2.1.1.295 GT2,GT4 H N-terminal domain of galactosyltransferase
KOILJNNC_00020 5.2e-188 S aspartate phosphatase
KOILJNNC_00021 1.5e-97 ynaD J Acetyltransferase (GNAT) domain
KOILJNNC_00023 4.7e-75 S CAAX protease self-immunity
KOILJNNC_00026 6.7e-254 xynT G MFS/sugar transport protein
KOILJNNC_00027 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
KOILJNNC_00028 1.2e-211 xylR GK ROK family
KOILJNNC_00029 1.4e-261 xylA 5.3.1.5 G Belongs to the xylose isomerase family
KOILJNNC_00030 5.3e-289 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
KOILJNNC_00031 3.4e-112 yokF 3.1.31.1 L RNA catabolic process
KOILJNNC_00032 6.8e-254 iolT EGP Major facilitator Superfamily
KOILJNNC_00033 1.5e-217 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOILJNNC_00035 4.5e-82 yncE S Protein of unknown function (DUF2691)
KOILJNNC_00036 1.9e-77 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
KOILJNNC_00037 1.2e-14
KOILJNNC_00040 7.3e-163 S Thymidylate synthase
KOILJNNC_00042 1.5e-121 S Domain of unknown function, YrpD
KOILJNNC_00045 7.9e-25 tatA U protein secretion
KOILJNNC_00046 1.2e-70
KOILJNNC_00047 1.7e-78 yndB S Activator of Hsp90 ATPase homolog 1-like protein
KOILJNNC_00050 2.2e-285 gerAA EG Spore germination protein
KOILJNNC_00051 1.7e-196 gerAB U Spore germination
KOILJNNC_00052 1.6e-219 gerLC S Spore germination protein
KOILJNNC_00053 1.8e-150 yndG S DoxX-like family
KOILJNNC_00054 3.2e-115 yndH S Domain of unknown function (DUF4166)
KOILJNNC_00055 3e-306 yndJ S YndJ-like protein
KOILJNNC_00057 2.1e-21 yndL S Replication protein
KOILJNNC_00058 2.3e-75 yndL S Replication protein
KOILJNNC_00059 1.7e-73 yndM S Protein of unknown function (DUF2512)
KOILJNNC_00060 5.8e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
KOILJNNC_00061 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KOILJNNC_00062 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
KOILJNNC_00063 2.1e-109 yneB L resolvase
KOILJNNC_00064 4.8e-32 ynzC S UPF0291 protein
KOILJNNC_00065 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KOILJNNC_00066 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
KOILJNNC_00067 1.8e-28 yneF S UPF0154 protein
KOILJNNC_00068 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
KOILJNNC_00069 7.8e-126 ccdA O cytochrome c biogenesis protein
KOILJNNC_00070 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
KOILJNNC_00071 8.6e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
KOILJNNC_00072 4.2e-74 yneK S Protein of unknown function (DUF2621)
KOILJNNC_00073 5.9e-64 hspX O Spore coat protein
KOILJNNC_00074 3.9e-19 sspP S Belongs to the SspP family
KOILJNNC_00075 2.5e-14 sspO S Belongs to the SspO family
KOILJNNC_00076 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KOILJNNC_00077 1.7e-90 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KOILJNNC_00079 3.1e-08 sspN S Small acid-soluble spore protein N family
KOILJNNC_00080 3.9e-35 tlp S Belongs to the Tlp family
KOILJNNC_00081 4.5e-73 yneP S Thioesterase-like superfamily
KOILJNNC_00082 2.2e-53 yneQ
KOILJNNC_00083 4.1e-49 yneR S Belongs to the HesB IscA family
KOILJNNC_00084 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
KOILJNNC_00085 6.6e-69 yccU S CoA-binding protein
KOILJNNC_00086 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOILJNNC_00087 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
KOILJNNC_00088 2.3e-12
KOILJNNC_00089 1.3e-57 ynfC
KOILJNNC_00090 1.2e-250 agcS E Sodium alanine symporter
KOILJNNC_00091 1.3e-295 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
KOILJNNC_00093 3.2e-247 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
KOILJNNC_00094 1.2e-293 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
KOILJNNC_00095 1.6e-79 yngA S membrane
KOILJNNC_00096 5.9e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KOILJNNC_00097 5.5e-104 yngC S membrane-associated protein
KOILJNNC_00098 3.6e-232 nrnB S phosphohydrolase (DHH superfamily)
KOILJNNC_00099 3.8e-287 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KOILJNNC_00100 2.7e-135 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KOILJNNC_00101 4e-167 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
KOILJNNC_00102 1.7e-31 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
KOILJNNC_00103 3.3e-250 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
KOILJNNC_00104 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KOILJNNC_00105 9.8e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
KOILJNNC_00106 2.2e-32 S Family of unknown function (DUF5367)
KOILJNNC_00107 3.7e-306 yngK T Glycosyl hydrolase-like 10
KOILJNNC_00108 2.8e-64 yngL S Protein of unknown function (DUF1360)
KOILJNNC_00109 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
KOILJNNC_00110 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00111 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00112 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00113 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_00114 4.9e-271 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
KOILJNNC_00115 8.4e-187 yoxA 5.1.3.3 G Aldose 1-epimerase
KOILJNNC_00116 1.9e-245 yoeA V MATE efflux family protein
KOILJNNC_00117 3.1e-98 yoeB S IseA DL-endopeptidase inhibitor
KOILJNNC_00119 2.2e-96 L Integrase
KOILJNNC_00120 1.1e-33 yoeD G Helix-turn-helix domain
KOILJNNC_00121 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KOILJNNC_00122 4.4e-155 gltR1 K Transcriptional regulator
KOILJNNC_00123 1.2e-183 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
KOILJNNC_00124 2.3e-292 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
KOILJNNC_00125 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
KOILJNNC_00126 7.8e-155 gltC K Transcriptional regulator
KOILJNNC_00127 9.2e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOILJNNC_00128 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOILJNNC_00129 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
KOILJNNC_00130 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_00131 7.8e-38 yoxC S Bacterial protein of unknown function (DUF948)
KOILJNNC_00132 1.7e-134 yoxB
KOILJNNC_00133 2.4e-95 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KOILJNNC_00134 3.4e-233 yoaB EGP Major facilitator Superfamily
KOILJNNC_00135 1e-276 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
KOILJNNC_00136 1.5e-183 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOILJNNC_00137 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KOILJNNC_00138 6.5e-34 yoaF
KOILJNNC_00140 7.7e-13
KOILJNNC_00141 8.2e-37 S Protein of unknown function (DUF4025)
KOILJNNC_00142 4.4e-183 mcpU NT methyl-accepting chemotaxis protein
KOILJNNC_00143 1.8e-278 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
KOILJNNC_00144 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
KOILJNNC_00145 3.4e-110 yoaK S Membrane
KOILJNNC_00146 8.1e-196 pelB 4.2.2.10, 4.2.2.2 G Amb_all
KOILJNNC_00147 1e-89 yoqW S Belongs to the SOS response-associated peptidase family
KOILJNNC_00150 3.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
KOILJNNC_00153 2.6e-83
KOILJNNC_00154 7.1e-172 yoaR V vancomycin resistance protein
KOILJNNC_00155 2.8e-74 yoaS S Protein of unknown function (DUF2975)
KOILJNNC_00156 4.4e-30 yozG K Transcriptional regulator
KOILJNNC_00157 2e-146 yoaT S Protein of unknown function (DUF817)
KOILJNNC_00158 7.3e-158 yoaU K LysR substrate binding domain
KOILJNNC_00159 1.1e-156 yijE EG EamA-like transporter family
KOILJNNC_00160 3.8e-75 yoaW
KOILJNNC_00161 1.1e-115 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
KOILJNNC_00162 1.6e-163 bla 3.5.2.6 V beta-lactamase
KOILJNNC_00165 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
KOILJNNC_00166 4e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
KOILJNNC_00167 3.1e-42
KOILJNNC_00169 2.8e-47
KOILJNNC_00170 7.7e-31 S SMI1-KNR4 cell-wall
KOILJNNC_00171 1e-42 S SMI1-KNR4 cell-wall
KOILJNNC_00172 2.1e-308 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
KOILJNNC_00174 8.8e-44 yokH G SMI1 / KNR4 family
KOILJNNC_00175 8.3e-276 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
KOILJNNC_00176 1.1e-50 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
KOILJNNC_00177 1.1e-132 yobQ K helix_turn_helix, arabinose operon control protein
KOILJNNC_00178 4.5e-140 yobR 2.3.1.1 J FR47-like protein
KOILJNNC_00179 3.6e-97 yobS K Transcriptional regulator
KOILJNNC_00180 7.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
KOILJNNC_00181 1.6e-82 yobU K Bacterial transcription activator, effector binding domain
KOILJNNC_00182 9.6e-172 yobV K WYL domain
KOILJNNC_00183 5.3e-90 yobW
KOILJNNC_00184 1e-51 czrA K transcriptional
KOILJNNC_00185 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KOILJNNC_00186 1.5e-92 yozB S membrane
KOILJNNC_00187 5.1e-142
KOILJNNC_00188 3.4e-91 yocC
KOILJNNC_00189 3.5e-185 yocD 3.4.17.13 V peptidase S66
KOILJNNC_00190 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KOILJNNC_00191 3.5e-197 desK 2.7.13.3 T Histidine kinase
KOILJNNC_00192 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_00193 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
KOILJNNC_00194 0.0 recQ 3.6.4.12 L DNA helicase
KOILJNNC_00195 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KOILJNNC_00196 3.3e-83 dksA T general stress protein
KOILJNNC_00197 1.2e-52 yocL
KOILJNNC_00198 6.2e-32
KOILJNNC_00199 3.7e-87 yocM O Belongs to the small heat shock protein (HSP20) family
KOILJNNC_00200 1.1e-40 yozN
KOILJNNC_00201 1.9e-36 yocN
KOILJNNC_00202 4.2e-56 yozO S Bacterial PH domain
KOILJNNC_00203 2.7e-31 yozC
KOILJNNC_00204 5.2e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
KOILJNNC_00205 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
KOILJNNC_00206 6.6e-164 sodA 1.15.1.1 P Superoxide dismutase
KOILJNNC_00207 4.5e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KOILJNNC_00208 5.1e-168 yocS S -transporter
KOILJNNC_00209 2.4e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
KOILJNNC_00210 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
KOILJNNC_00211 0.0 yojO P Von Willebrand factor
KOILJNNC_00212 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
KOILJNNC_00213 6.6e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KOILJNNC_00214 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KOILJNNC_00215 1.2e-230 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
KOILJNNC_00216 7.6e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOILJNNC_00218 4.2e-245 norM V Multidrug efflux pump
KOILJNNC_00219 3.2e-150 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KOILJNNC_00220 2.1e-125 yojG S deacetylase
KOILJNNC_00221 2.2e-60 yojF S Protein of unknown function (DUF1806)
KOILJNNC_00222 1.5e-43
KOILJNNC_00223 1.1e-161 rarD S -transporter
KOILJNNC_00224 5.5e-59 yozR S COG0071 Molecular chaperone (small heat shock protein)
KOILJNNC_00225 3.4e-09
KOILJNNC_00226 8.5e-206 gntP EG COG2610 H gluconate symporter and related permeases
KOILJNNC_00227 8e-64 yodA S tautomerase
KOILJNNC_00228 4.4e-55 yodB K transcriptional
KOILJNNC_00229 1.4e-107 yodC C nitroreductase
KOILJNNC_00230 2.1e-111 mhqD S Carboxylesterase
KOILJNNC_00231 1.1e-153 yodE E COG0346 Lactoylglutathione lyase and related lyases
KOILJNNC_00232 6.2e-28 S Protein of unknown function (DUF3311)
KOILJNNC_00233 1.2e-269 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOILJNNC_00234 2.8e-252 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
KOILJNNC_00235 1.8e-127 yodH Q Methyltransferase
KOILJNNC_00236 1.5e-23 yodI
KOILJNNC_00237 5.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
KOILJNNC_00238 4.1e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
KOILJNNC_00239 5.3e-09
KOILJNNC_00240 3.6e-54 yodL S YodL-like
KOILJNNC_00241 6e-106 yodM 3.6.1.27 I Acid phosphatase homologues
KOILJNNC_00242 2.8e-24 yozD S YozD-like protein
KOILJNNC_00244 6e-123 yodN
KOILJNNC_00245 1.4e-36 yozE S Belongs to the UPF0346 family
KOILJNNC_00246 6.4e-47 yokU S YokU-like protein, putative antitoxin
KOILJNNC_00247 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
KOILJNNC_00248 3.9e-153 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
KOILJNNC_00249 1.8e-256 yodQ 3.5.1.16 E Acetylornithine deacetylase
KOILJNNC_00250 1e-116 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KOILJNNC_00251 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KOILJNNC_00252 9.9e-247 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KOILJNNC_00254 1.8e-144 yiiD K acetyltransferase
KOILJNNC_00255 1.8e-253 cgeD M maturation of the outermost layer of the spore
KOILJNNC_00256 3.5e-38 cgeC
KOILJNNC_00257 1.2e-65 cgeA
KOILJNNC_00258 6.3e-187 cgeB S Spore maturation protein
KOILJNNC_00259 1.3e-210 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
KOILJNNC_00260 1.3e-124 4.2.1.115 GM Polysaccharide biosynthesis protein
KOILJNNC_00261 2.9e-78 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
KOILJNNC_00262 8.6e-101 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KOILJNNC_00263 1.6e-70 ypoP K transcriptional
KOILJNNC_00264 1.7e-222 mepA V MATE efflux family protein
KOILJNNC_00265 1.2e-28 ypmT S Uncharacterized ympT
KOILJNNC_00266 1.1e-98 ypmS S protein conserved in bacteria
KOILJNNC_00267 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
KOILJNNC_00268 4.6e-108 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
KOILJNNC_00269 8.9e-40 ypmP S Protein of unknown function (DUF2535)
KOILJNNC_00270 3.5e-241 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KOILJNNC_00271 3.7e-182 pspF K Transcriptional regulator
KOILJNNC_00272 4.2e-110 hlyIII S protein, Hemolysin III
KOILJNNC_00273 1.4e-110 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KOILJNNC_00274 1.5e-94 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KOILJNNC_00275 4.8e-156 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KOILJNNC_00276 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KOILJNNC_00277 7.8e-114 ypjP S YpjP-like protein
KOILJNNC_00278 1e-142 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
KOILJNNC_00279 1.7e-75 yphP S Belongs to the UPF0403 family
KOILJNNC_00280 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
KOILJNNC_00281 1.3e-154 ypgR C COG0694 Thioredoxin-like proteins and domains
KOILJNNC_00282 4.3e-104 ypgQ S phosphohydrolase
KOILJNNC_00283 7.1e-86 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
KOILJNNC_00284 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KOILJNNC_00286 5.9e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
KOILJNNC_00287 7.9e-31 cspD K Cold-shock protein
KOILJNNC_00288 3.8e-16 degR
KOILJNNC_00289 1.1e-30 S Protein of unknown function (DUF2564)
KOILJNNC_00290 3e-29 ypeQ S Zinc-finger
KOILJNNC_00291 4.7e-135 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
KOILJNNC_00292 4.5e-106 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
KOILJNNC_00293 2.1e-67 rnhA 3.1.26.4 L Ribonuclease
KOILJNNC_00295 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
KOILJNNC_00296 2e-07
KOILJNNC_00297 1e-38 ypbS S Protein of unknown function (DUF2533)
KOILJNNC_00298 0.0 ypbR S Dynamin family
KOILJNNC_00300 1.1e-86 ypbQ S protein conserved in bacteria
KOILJNNC_00301 5.9e-205 bcsA Q Naringenin-chalcone synthase
KOILJNNC_00302 1.9e-226 pbuX F xanthine
KOILJNNC_00303 4.8e-97 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
KOILJNNC_00304 1.1e-291 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KOILJNNC_00305 7.3e-170 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
KOILJNNC_00306 4.6e-103 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
KOILJNNC_00307 8.4e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
KOILJNNC_00308 1.5e-186 ptxS K transcriptional
KOILJNNC_00309 2.2e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
KOILJNNC_00310 9.3e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_00311 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
KOILJNNC_00313 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
KOILJNNC_00314 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
KOILJNNC_00315 9.7e-92 ypsA S Belongs to the UPF0398 family
KOILJNNC_00316 1.9e-236 yprB L RNase_H superfamily
KOILJNNC_00317 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
KOILJNNC_00318 2.3e-79 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
KOILJNNC_00319 7.3e-71 hspX O Belongs to the small heat shock protein (HSP20) family
KOILJNNC_00320 1e-47 yppG S YppG-like protein
KOILJNNC_00322 1.5e-11 yppE S Bacterial domain of unknown function (DUF1798)
KOILJNNC_00325 3.5e-185 yppC S Protein of unknown function (DUF2515)
KOILJNNC_00326 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
KOILJNNC_00327 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
KOILJNNC_00328 4.7e-93 ypoC
KOILJNNC_00329 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KOILJNNC_00330 5.7e-129 dnaD L DNA replication protein DnaD
KOILJNNC_00331 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
KOILJNNC_00332 4.4e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
KOILJNNC_00333 2.2e-79 ypmB S protein conserved in bacteria
KOILJNNC_00334 6.7e-23 ypmA S Protein of unknown function (DUF4264)
KOILJNNC_00335 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
KOILJNNC_00336 1e-63 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KOILJNNC_00337 1.2e-155 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KOILJNNC_00338 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
KOILJNNC_00339 3.3e-183 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
KOILJNNC_00340 1.3e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
KOILJNNC_00341 2.2e-207 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
KOILJNNC_00342 1.7e-128 bshB1 S proteins, LmbE homologs
KOILJNNC_00343 7.2e-71 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
KOILJNNC_00344 2e-146 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
KOILJNNC_00345 6.9e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
KOILJNNC_00346 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
KOILJNNC_00347 1.3e-142 ypjB S sporulation protein
KOILJNNC_00348 2.2e-97 ypjA S membrane
KOILJNNC_00349 4.3e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
KOILJNNC_00350 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
KOILJNNC_00351 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
KOILJNNC_00352 4.2e-77 ypiF S Protein of unknown function (DUF2487)
KOILJNNC_00353 1.1e-98 ypiB S Belongs to the UPF0302 family
KOILJNNC_00354 5.9e-233 S COG0457 FOG TPR repeat
KOILJNNC_00355 2.2e-235 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
KOILJNNC_00356 2.6e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
KOILJNNC_00357 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KOILJNNC_00358 1.2e-143 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
KOILJNNC_00359 2.6e-230 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KOILJNNC_00360 3e-116 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
KOILJNNC_00361 4.7e-113 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
KOILJNNC_00362 6.1e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KOILJNNC_00363 2.8e-293 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOILJNNC_00364 3.9e-63 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
KOILJNNC_00365 3.4e-205 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KOILJNNC_00366 1.2e-216 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KOILJNNC_00367 4.2e-141 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
KOILJNNC_00368 4.5e-79 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
KOILJNNC_00369 4.5e-194 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOILJNNC_00370 7.2e-132 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
KOILJNNC_00371 1.3e-137 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
KOILJNNC_00372 2.3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
KOILJNNC_00373 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
KOILJNNC_00374 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
KOILJNNC_00375 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
KOILJNNC_00376 5.1e-136 yphF
KOILJNNC_00377 1.2e-18 yphE S Protein of unknown function (DUF2768)
KOILJNNC_00378 5.6e-181 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
KOILJNNC_00379 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
KOILJNNC_00380 1.6e-28 ypzH
KOILJNNC_00381 2.5e-161 seaA S YIEGIA protein
KOILJNNC_00382 6.7e-102 yphA
KOILJNNC_00383 1e-07 S YpzI-like protein
KOILJNNC_00384 3.2e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
KOILJNNC_00385 1.6e-205 rpsA 1.17.7.4 J Ribosomal protein S1
KOILJNNC_00386 6.1e-112 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
KOILJNNC_00387 1.8e-23 S Family of unknown function (DUF5359)
KOILJNNC_00388 1e-111 ypfA M Flagellar protein YcgR
KOILJNNC_00389 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
KOILJNNC_00390 3.3e-153 sleB 3.5.1.28 M Spore cortex-lytic enzyme
KOILJNNC_00391 2.3e-119 prsW S Involved in the degradation of specific anti-sigma factors
KOILJNNC_00392 4.8e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
KOILJNNC_00393 2.6e-244 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOILJNNC_00394 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KOILJNNC_00395 1.7e-145 ypbG S Calcineurin-like phosphoesterase superfamily domain
KOILJNNC_00396 8.2e-81 ypbF S Protein of unknown function (DUF2663)
KOILJNNC_00397 1.9e-74 ypbE M Lysin motif
KOILJNNC_00398 1.1e-99 ypbD S metal-dependent membrane protease
KOILJNNC_00399 9.2e-286 recQ 3.6.4.12 L DNA helicase
KOILJNNC_00400 1e-198 ypbB 5.1.3.1 S protein conserved in bacteria
KOILJNNC_00401 4.7e-41 fer C Ferredoxin
KOILJNNC_00402 4.6e-84 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
KOILJNNC_00403 7.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOILJNNC_00404 7.2e-133 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
KOILJNNC_00405 4.1e-198 rsiX
KOILJNNC_00406 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_00407 0.0 resE 2.7.13.3 T Histidine kinase
KOILJNNC_00408 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_00409 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
KOILJNNC_00410 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
KOILJNNC_00411 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
KOILJNNC_00412 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOILJNNC_00413 1.9e-87 spmB S Spore maturation protein
KOILJNNC_00414 3.5e-103 spmA S Spore maturation protein
KOILJNNC_00415 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
KOILJNNC_00416 7.6e-97 ypuI S Protein of unknown function (DUF3907)
KOILJNNC_00417 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KOILJNNC_00418 1.3e-129 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KOILJNNC_00419 2.7e-91 ypuF S Domain of unknown function (DUF309)
KOILJNNC_00420 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_00421 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
KOILJNNC_00422 2.9e-229 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KOILJNNC_00423 3.3e-115 ribE 2.5.1.9 H Riboflavin synthase
KOILJNNC_00424 2.9e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KOILJNNC_00425 7.8e-55 ypuD
KOILJNNC_00426 3.4e-100 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KOILJNNC_00427 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
KOILJNNC_00430 2.6e-07 eaeH M Domain of Unknown Function (DUF1259)
KOILJNNC_00432 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KOILJNNC_00433 3.6e-149 ypuA S Secreted protein
KOILJNNC_00434 3.4e-255 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
KOILJNNC_00435 1.4e-273 spoVAF EG Stage V sporulation protein AF
KOILJNNC_00436 1.4e-110 spoVAEA S stage V sporulation protein
KOILJNNC_00437 2.2e-57 spoVAEB S stage V sporulation protein
KOILJNNC_00438 9e-192 spoVAD I Stage V sporulation protein AD
KOILJNNC_00439 2.3e-78 spoVAC S stage V sporulation protein AC
KOILJNNC_00440 1e-67 spoVAB S Stage V sporulation protein AB
KOILJNNC_00441 9.6e-112 spoVAA S Stage V sporulation protein AA
KOILJNNC_00442 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_00443 2.3e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
KOILJNNC_00444 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
KOILJNNC_00445 5.3e-212 dacF 3.4.16.4 M Belongs to the peptidase S11 family
KOILJNNC_00446 2.9e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KOILJNNC_00447 3e-231 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
KOILJNNC_00448 5.7e-166 xerD L recombinase XerD
KOILJNNC_00449 3.7e-37 S Protein of unknown function (DUF4227)
KOILJNNC_00450 2.4e-80 fur P Belongs to the Fur family
KOILJNNC_00451 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
KOILJNNC_00452 3.2e-30 yqkK
KOILJNNC_00453 5.5e-242 mleA 1.1.1.38 C malic enzyme
KOILJNNC_00454 1.2e-234 mleN C Na H antiporter
KOILJNNC_00455 4.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
KOILJNNC_00456 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
KOILJNNC_00457 4.5e-58 ansR K Transcriptional regulator
KOILJNNC_00458 9e-220 yqxK 3.6.4.12 L DNA helicase
KOILJNNC_00459 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
KOILJNNC_00461 3.1e-167 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
KOILJNNC_00462 3.1e-12 yqkE S Protein of unknown function (DUF3886)
KOILJNNC_00463 5.5e-172 yqkD S COG1073 Hydrolases of the alpha beta superfamily
KOILJNNC_00464 9.4e-39 yqkC S Protein of unknown function (DUF2552)
KOILJNNC_00465 2.8e-54 yqkB S Belongs to the HesB IscA family
KOILJNNC_00466 1e-190 yqkA K GrpB protein
KOILJNNC_00467 2e-58 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
KOILJNNC_00468 1.1e-86 yqjY K acetyltransferase
KOILJNNC_00469 2.2e-49 S YolD-like protein
KOILJNNC_00470 3.5e-238 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOILJNNC_00472 1.3e-224 yqjV G Major Facilitator Superfamily
KOILJNNC_00474 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_00475 1.2e-177 coaA 2.7.1.33 F Pantothenic acid kinase
KOILJNNC_00476 3.2e-261 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
KOILJNNC_00477 5e-142 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_00478 4.8e-179 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
KOILJNNC_00479 7.3e-147 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOILJNNC_00480 0.0 rocB E arginine degradation protein
KOILJNNC_00481 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
KOILJNNC_00482 2.9e-142 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOILJNNC_00483 3e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOILJNNC_00484 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
KOILJNNC_00485 5.2e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KOILJNNC_00486 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOILJNNC_00487 5.2e-234 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KOILJNNC_00488 2.6e-24 yqzJ
KOILJNNC_00489 5.5e-139 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOILJNNC_00490 1e-136 yqjF S Uncharacterized conserved protein (COG2071)
KOILJNNC_00491 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
KOILJNNC_00492 2.3e-287 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
KOILJNNC_00493 3e-72 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
KOILJNNC_00495 3.4e-97 yqjB S protein conserved in bacteria
KOILJNNC_00496 5.8e-172 yqjA S Putative aromatic acid exporter C-terminal domain
KOILJNNC_00497 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KOILJNNC_00498 9e-108 artQ E COG0765 ABC-type amino acid transport system, permease component
KOILJNNC_00499 2.6e-135 artP ET Belongs to the bacterial solute-binding protein 3 family
KOILJNNC_00500 9.3e-77 yqiW S Belongs to the UPF0403 family
KOILJNNC_00501 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KOILJNNC_00502 5.1e-207 norA EGP Major facilitator Superfamily
KOILJNNC_00503 5.8e-152 bmrR K helix_turn_helix, mercury resistance
KOILJNNC_00504 4.1e-218 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOILJNNC_00505 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KOILJNNC_00506 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KOILJNNC_00507 3.7e-268 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KOILJNNC_00508 2.7e-202 buk 2.7.2.7 C Belongs to the acetokinase family
KOILJNNC_00509 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOILJNNC_00510 2.5e-153 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
KOILJNNC_00511 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
KOILJNNC_00512 4e-34 yqzF S Protein of unknown function (DUF2627)
KOILJNNC_00513 1.6e-163 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
KOILJNNC_00514 9.1e-275 prpD 4.2.1.79 S 2-methylcitrate dehydratase
KOILJNNC_00515 3.2e-206 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
KOILJNNC_00516 8.2e-210 mmgC I acyl-CoA dehydrogenase
KOILJNNC_00517 1.5e-155 hbdA 1.1.1.157 I Dehydrogenase
KOILJNNC_00518 1e-218 mmgA 2.3.1.9 I Belongs to the thiolase family
KOILJNNC_00519 3.2e-130 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KOILJNNC_00520 2.1e-106 amiC 3.5.1.28 M Cell wall hydrolase autolysin
KOILJNNC_00521 6e-27
KOILJNNC_00522 1.2e-213 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
KOILJNNC_00524 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
KOILJNNC_00525 3.6e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
KOILJNNC_00526 9.3e-306 recN L May be involved in recombinational repair of damaged DNA
KOILJNNC_00527 1.7e-78 argR K Regulates arginine biosynthesis genes
KOILJNNC_00528 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
KOILJNNC_00529 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KOILJNNC_00530 2.5e-161 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
KOILJNNC_00531 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOILJNNC_00532 2.9e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
KOILJNNC_00533 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KOILJNNC_00534 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KOILJNNC_00535 2.1e-67 yqhY S protein conserved in bacteria
KOILJNNC_00536 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
KOILJNNC_00537 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
KOILJNNC_00538 1.6e-85 spoIIIAH S SpoIIIAH-like protein
KOILJNNC_00539 6.9e-103 spoIIIAG S stage III sporulation protein AG
KOILJNNC_00540 9e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
KOILJNNC_00541 2.9e-197 spoIIIAE S stage III sporulation protein AE
KOILJNNC_00542 2.3e-58 spoIIIAD S Stage III sporulation protein AD
KOILJNNC_00543 7.6e-29 spoIIIAC S stage III sporulation protein AC
KOILJNNC_00544 1.1e-84 spoIIIAB S Stage III sporulation protein
KOILJNNC_00545 1e-170 spoIIIAA S stage III sporulation protein AA
KOILJNNC_00546 7.9e-37 yqhV S Protein of unknown function (DUF2619)
KOILJNNC_00547 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KOILJNNC_00548 2.9e-172 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KOILJNNC_00549 4.2e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
KOILJNNC_00550 6.6e-93 yqhR S Conserved membrane protein YqhR
KOILJNNC_00551 8.8e-173 yqhQ S Protein of unknown function (DUF1385)
KOILJNNC_00552 2.2e-61 yqhP
KOILJNNC_00553 1.5e-163 yqhO S esterase of the alpha-beta hydrolase superfamily
KOILJNNC_00554 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
KOILJNNC_00555 2.6e-160 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
KOILJNNC_00556 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
KOILJNNC_00557 1.5e-285 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KOILJNNC_00558 4.9e-254 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KOILJNNC_00559 1.1e-206 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
KOILJNNC_00560 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KOILJNNC_00561 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
KOILJNNC_00562 1.2e-24 sinI S Anti-repressor SinI
KOILJNNC_00563 1e-54 sinR K transcriptional
KOILJNNC_00564 1.9e-141 tasA S Cell division protein FtsN
KOILJNNC_00565 6.7e-59 sipW 3.4.21.89 U Signal peptidase
KOILJNNC_00566 5.1e-115 yqxM
KOILJNNC_00567 7.3e-54 yqzG S Protein of unknown function (DUF3889)
KOILJNNC_00568 1.4e-26 yqzE S YqzE-like protein
KOILJNNC_00569 2e-43 S ComG operon protein 7
KOILJNNC_00570 1.7e-34 comGF U Putative Competence protein ComGF
KOILJNNC_00571 9e-59 comGE
KOILJNNC_00572 4.9e-70 gspH NU protein transport across the cell outer membrane
KOILJNNC_00573 3e-47 comGC U Required for transformation and DNA binding
KOILJNNC_00574 7.6e-170 comGB NU COG1459 Type II secretory pathway, component PulF
KOILJNNC_00575 5.6e-200 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KOILJNNC_00578 1.4e-173 corA P Mg2 transporter protein
KOILJNNC_00579 3.7e-238 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KOILJNNC_00580 5.6e-147 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KOILJNNC_00582 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
KOILJNNC_00583 1.8e-37 yqgY S Protein of unknown function (DUF2626)
KOILJNNC_00584 2.1e-122 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
KOILJNNC_00585 8.9e-23 yqgW S Protein of unknown function (DUF2759)
KOILJNNC_00586 6.9e-50 yqgV S Thiamine-binding protein
KOILJNNC_00587 1.5e-197 yqgU
KOILJNNC_00588 1.3e-220 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
KOILJNNC_00589 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOILJNNC_00590 2e-180 glcK 2.7.1.2 G Glucokinase
KOILJNNC_00591 3.1e-33 yqgQ S Protein conserved in bacteria
KOILJNNC_00592 6.6e-263 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
KOILJNNC_00593 2.5e-09 yqgO
KOILJNNC_00594 7.4e-103 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KOILJNNC_00595 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
KOILJNNC_00596 3e-196 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
KOILJNNC_00598 9.2e-51 yqzD
KOILJNNC_00599 1.9e-75 yqzC S YceG-like family
KOILJNNC_00600 3.7e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOILJNNC_00601 1.4e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
KOILJNNC_00602 1.3e-157 pstA P Phosphate transport system permease
KOILJNNC_00603 7.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
KOILJNNC_00604 1.5e-150 pstS P Phosphate
KOILJNNC_00605 0.0 pbpA 3.4.16.4 M penicillin-binding protein
KOILJNNC_00606 2.5e-231 yqgE EGP Major facilitator superfamily
KOILJNNC_00607 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
KOILJNNC_00608 4e-73 yqgC S protein conserved in bacteria
KOILJNNC_00609 3.9e-131 yqgB S Protein of unknown function (DUF1189)
KOILJNNC_00610 5.2e-47 yqfZ M LysM domain
KOILJNNC_00611 6.3e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KOILJNNC_00612 4.3e-62 yqfX S membrane
KOILJNNC_00613 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
KOILJNNC_00614 1.9e-77 zur P Belongs to the Fur family
KOILJNNC_00615 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KOILJNNC_00616 2.1e-36 yqfT S Protein of unknown function (DUF2624)
KOILJNNC_00617 1.3e-165 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KOILJNNC_00618 1.2e-241 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
KOILJNNC_00619 7e-08 yqfQ S YqfQ-like protein
KOILJNNC_00620 1.3e-176 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KOILJNNC_00621 3.3e-211 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KOILJNNC_00622 6.8e-116 trmK 2.1.1.217 S SAM-dependent methyltransferase
KOILJNNC_00623 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
KOILJNNC_00624 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
KOILJNNC_00625 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
KOILJNNC_00626 4.5e-88 yaiI S Belongs to the UPF0178 family
KOILJNNC_00627 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
KOILJNNC_00628 4.5e-112 ccpN K CBS domain
KOILJNNC_00629 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
KOILJNNC_00630 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
KOILJNNC_00631 3.4e-143 recO L Involved in DNA repair and RecF pathway recombination
KOILJNNC_00632 8.4e-19 S YqzL-like protein
KOILJNNC_00633 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KOILJNNC_00634 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
KOILJNNC_00635 1.8e-60 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
KOILJNNC_00636 6.7e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KOILJNNC_00637 0.0 yqfF S membrane-associated HD superfamily hydrolase
KOILJNNC_00639 6.1e-174 phoH T Phosphate starvation-inducible protein PhoH
KOILJNNC_00640 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
KOILJNNC_00641 2.7e-45 yqfC S sporulation protein YqfC
KOILJNNC_00642 7.6e-28 yqfB
KOILJNNC_00643 3.7e-121 yqfA S UPF0365 protein
KOILJNNC_00644 1.3e-227 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
KOILJNNC_00645 2.5e-61 yqeY S Yqey-like protein
KOILJNNC_00646 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
KOILJNNC_00647 2.3e-157 yqeW P COG1283 Na phosphate symporter
KOILJNNC_00648 1.3e-259 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
KOILJNNC_00649 3.6e-140 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
KOILJNNC_00650 5.4e-175 prmA J Methylates ribosomal protein L11
KOILJNNC_00651 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
KOILJNNC_00652 0.0 dnaK O Heat shock 70 kDa protein
KOILJNNC_00653 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KOILJNNC_00654 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
KOILJNNC_00655 1.6e-216 hemN H Involved in the biosynthesis of porphyrin-containing compound
KOILJNNC_00656 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
KOILJNNC_00657 3.6e-52 yqxA S Protein of unknown function (DUF3679)
KOILJNNC_00658 4.5e-222 spoIIP M stage II sporulation protein P
KOILJNNC_00659 5e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KOILJNNC_00660 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
KOILJNNC_00661 1.6e-188 holA 2.7.7.7 L DNA polymerase III delta subunit
KOILJNNC_00662 4.1e-15 S YqzM-like protein
KOILJNNC_00663 0.0 comEC S Competence protein ComEC
KOILJNNC_00664 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
KOILJNNC_00665 3.3e-104 wza L COG1555 DNA uptake protein and related DNA-binding proteins
KOILJNNC_00666 2.5e-147 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KOILJNNC_00667 1.4e-138 yqeM Q Methyltransferase
KOILJNNC_00668 9.9e-61 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
KOILJNNC_00669 3.7e-102 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
KOILJNNC_00670 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KOILJNNC_00671 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
KOILJNNC_00672 2.3e-156 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KOILJNNC_00673 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
KOILJNNC_00674 5.3e-95 yqeG S hydrolase of the HAD superfamily
KOILJNNC_00676 1.8e-141 yqeF E GDSL-like Lipase/Acylhydrolase
KOILJNNC_00677 7.8e-132 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KOILJNNC_00678 1.8e-105 yqeD S SNARE associated Golgi protein
KOILJNNC_00679 9.4e-169 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
KOILJNNC_00680 4.1e-130 yqeB
KOILJNNC_00681 7.6e-73 nucB M Deoxyribonuclease NucA/NucB
KOILJNNC_00682 3.1e-125 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_00683 1.5e-97 ywrO S Flavodoxin-like fold
KOILJNNC_00684 2.8e-79 S Protein of unknown function with HXXEE motif
KOILJNNC_00685 1.2e-60 hosA K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_00686 1.6e-59 2.8.1.7, 4.4.1.16 P Rhodanese Homology Domain
KOILJNNC_00687 1.6e-53 ydcG S EVE domain
KOILJNNC_00689 3.2e-206 S Aspartate phosphatase response regulator
KOILJNNC_00690 3.4e-168 yobL S Bacterial EndoU nuclease
KOILJNNC_00691 2.6e-48
KOILJNNC_00692 5e-38
KOILJNNC_00694 2.6e-116 EGP Necrosis inducing protein (NPP1)
KOILJNNC_00696 6.6e-156 axeA S Carbohydrate esterase, sialic acid-specific acetylesterase
KOILJNNC_00697 3e-90 K Transcriptional regulator PadR-like family
KOILJNNC_00698 2.7e-180 yjlA EG Putative multidrug resistance efflux transporter
KOILJNNC_00699 1.9e-111 K COG1802 Transcriptional regulators
KOILJNNC_00700 3.5e-111 yrkJ S membrane transporter protein
KOILJNNC_00701 5.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
KOILJNNC_00702 8.4e-207 yrkH P Rhodanese Homology Domain
KOILJNNC_00703 2.4e-98 yrkF OP Belongs to the sulfur carrier protein TusA family
KOILJNNC_00705 1.4e-46 P Rhodanese Homology Domain
KOILJNNC_00706 5.6e-83 yrkE O DsrE/DsrF/DrsH-like family
KOILJNNC_00707 7.8e-39 yrkD S protein conserved in bacteria
KOILJNNC_00708 7.6e-23
KOILJNNC_00709 3.8e-107 yrkC G Cupin domain
KOILJNNC_00710 2.2e-148 bltR K helix_turn_helix, mercury resistance
KOILJNNC_00711 3e-210 blt EGP Major facilitator Superfamily
KOILJNNC_00712 2.2e-81 bltD 2.3.1.57 K FR47-like protein
KOILJNNC_00713 2.3e-232 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KOILJNNC_00714 3.9e-16 S YrzO-like protein
KOILJNNC_00715 1e-168 yrdR EG EamA-like transporter family
KOILJNNC_00716 3e-159 yrdQ K Transcriptional regulator
KOILJNNC_00717 5.1e-153 leuB1 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOILJNNC_00718 3.1e-78 pucE 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KOILJNNC_00719 1.3e-151 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KOILJNNC_00720 0.0 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KOILJNNC_00721 1.2e-82 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KOILJNNC_00722 3.4e-162 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KOILJNNC_00723 1.6e-145 S Fusaric acid resistance protein-like
KOILJNNC_00724 1.7e-151 eaeH M Domain of Unknown Function (DUF1259)
KOILJNNC_00726 4.3e-197 trkA P Oxidoreductase
KOILJNNC_00727 2.3e-149 czcD P COG1230 Co Zn Cd efflux system component
KOILJNNC_00728 6.5e-66 yodA S tautomerase
KOILJNNC_00729 1.5e-161 gltR K LysR substrate binding domain
KOILJNNC_00730 6.6e-51 C COG2041 Sulfite oxidase and related enzymes
KOILJNNC_00731 3.5e-228 brnQ E Component of the transport system for branched-chain amino acids
KOILJNNC_00732 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
KOILJNNC_00733 3.3e-138 azlC E AzlC protein
KOILJNNC_00734 6.3e-79 bkdR K helix_turn_helix ASNC type
KOILJNNC_00735 6.5e-44 yrdF K ribonuclease inhibitor
KOILJNNC_00736 3e-221 cypA C Cytochrome P450
KOILJNNC_00737 1.2e-17 K Acetyltransferase (GNAT) family
KOILJNNC_00738 6.7e-64 K Transcriptional regulator
KOILJNNC_00739 1.2e-164 scrR K transcriptional
KOILJNNC_00740 2.9e-227 msmE G Bacterial extracellular solute-binding protein
KOILJNNC_00741 3.9e-149 msmF P Binding-protein-dependent transport system inner membrane component
KOILJNNC_00742 1.1e-139 msmG P PFAM binding-protein-dependent transport systems inner membrane component
KOILJNNC_00743 2.7e-198 rafB P LacY proton/sugar symporter
KOILJNNC_00744 5.7e-251 cscA 3.2.1.26 GH32 G invertase
KOILJNNC_00745 1e-147 2.7.1.4 G Belongs to the carbohydrate kinase PfkB family
KOILJNNC_00746 5.5e-74 maa 2.3.1.79 S COG0110 Acetyltransferase (isoleucine patch superfamily)
KOILJNNC_00747 1.2e-100 yrdC 3.5.1.19 Q Isochorismatase family
KOILJNNC_00748 1.5e-54 S Protein of unknown function (DUF2568)
KOILJNNC_00750 6.4e-90 yrdA S DinB family
KOILJNNC_00751 4.2e-166 aadK G Streptomycin adenylyltransferase
KOILJNNC_00752 8.4e-193 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
KOILJNNC_00753 8.5e-145 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOILJNNC_00754 1.6e-123 yrpD S Domain of unknown function, YrpD
KOILJNNC_00755 1.6e-97 flr S Flavin reductase like domain
KOILJNNC_00756 9.4e-118 bmrR K helix_turn_helix, mercury resistance
KOILJNNC_00757 5.6e-50 yjbR S YjbR
KOILJNNC_00758 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
KOILJNNC_00759 2.3e-93 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_00760 1.9e-186 yrpG C Aldo/keto reductase family
KOILJNNC_00761 7.2e-155 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
KOILJNNC_00762 1.9e-40 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_00763 2.4e-150 S Alpha beta hydrolase
KOILJNNC_00764 2.2e-60 T sh3 domain protein
KOILJNNC_00765 5.4e-61 T sh3 domain protein
KOILJNNC_00767 3e-63 E Glyoxalase-like domain
KOILJNNC_00768 3.4e-36 yraG
KOILJNNC_00769 6.4e-63 yraF M Spore coat protein
KOILJNNC_00770 5.7e-219 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KOILJNNC_00771 2.8e-25 yraE
KOILJNNC_00772 2.8e-48 yraD M Spore coat protein
KOILJNNC_00773 1.7e-46 yraB K helix_turn_helix, mercury resistance
KOILJNNC_00774 1.3e-198 adhA 1.1.1.1 C alcohol dehydrogenase
KOILJNNC_00775 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
KOILJNNC_00776 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KOILJNNC_00777 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
KOILJNNC_00778 9.9e-117 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
KOILJNNC_00779 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
KOILJNNC_00780 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
KOILJNNC_00781 0.0 levR K PTS system fructose IIA component
KOILJNNC_00782 1.5e-253 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_00783 1.1e-105 yrhP E LysE type translocator
KOILJNNC_00784 1.7e-148 yrhO K Archaeal transcriptional regulator TrmB
KOILJNNC_00785 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_00786 1.2e-149 rsiV S Protein of unknown function (DUF3298)
KOILJNNC_00787 0.0 yrhL I Acyltransferase family
KOILJNNC_00788 9.1e-44 yrhK S YrhK-like protein
KOILJNNC_00789 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KOILJNNC_00790 8.2e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
KOILJNNC_00791 7.9e-94 yrhH Q methyltransferase
KOILJNNC_00794 6.7e-142 focA P Formate nitrite
KOILJNNC_00795 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
KOILJNNC_00796 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KOILJNNC_00797 7.1e-78 yrhD S Protein of unknown function (DUF1641)
KOILJNNC_00798 4.6e-35 yrhC S YrhC-like protein
KOILJNNC_00799 7e-209 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KOILJNNC_00800 2.3e-170 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
KOILJNNC_00801 9.4e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KOILJNNC_00802 1.9e-118 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
KOILJNNC_00803 1e-25 yrzA S Protein of unknown function (DUF2536)
KOILJNNC_00804 4.2e-63 yrrS S Protein of unknown function (DUF1510)
KOILJNNC_00805 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
KOILJNNC_00806 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
KOILJNNC_00807 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
KOILJNNC_00808 2.7e-246 yegQ O COG0826 Collagenase and related proteases
KOILJNNC_00809 2.9e-173 yegQ O Peptidase U32
KOILJNNC_00810 1.1e-118 yrrM 2.1.1.104 S O-methyltransferase
KOILJNNC_00811 3.7e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KOILJNNC_00812 1.2e-45 yrzB S Belongs to the UPF0473 family
KOILJNNC_00813 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KOILJNNC_00814 1.7e-41 yrzL S Belongs to the UPF0297 family
KOILJNNC_00815 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KOILJNNC_00816 2.7e-170 yrrI S AI-2E family transporter
KOILJNNC_00817 1.2e-129 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KOILJNNC_00818 4.3e-144 glnH ET Belongs to the bacterial solute-binding protein 3 family
KOILJNNC_00819 1.8e-108 gluC P ABC transporter
KOILJNNC_00820 7.6e-107 glnP P ABC transporter
KOILJNNC_00821 8e-08 S Protein of unknown function (DUF3918)
KOILJNNC_00822 9.8e-31 yrzR
KOILJNNC_00823 1.7e-81 yrrD S protein conserved in bacteria
KOILJNNC_00824 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
KOILJNNC_00825 1.4e-15 S COG0457 FOG TPR repeat
KOILJNNC_00826 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
KOILJNNC_00827 4.4e-211 iscS 2.8.1.7 E Cysteine desulfurase
KOILJNNC_00828 1.2e-70 cymR K Transcriptional regulator
KOILJNNC_00829 9.7e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
KOILJNNC_00830 4e-136 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
KOILJNNC_00831 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KOILJNNC_00832 9.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
KOILJNNC_00834 2.9e-258 lytH 3.5.1.28 M COG3103 SH3 domain protein
KOILJNNC_00835 2.9e-70 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
KOILJNNC_00836 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KOILJNNC_00837 8.6e-90 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
KOILJNNC_00838 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
KOILJNNC_00839 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
KOILJNNC_00840 2.8e-85 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
KOILJNNC_00841 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KOILJNNC_00842 1.6e-48 yrzD S Post-transcriptional regulator
KOILJNNC_00843 8.2e-269 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_00844 5.4e-113 yrbG S membrane
KOILJNNC_00845 1.2e-74 yrzE S Protein of unknown function (DUF3792)
KOILJNNC_00846 8e-39 yajC U Preprotein translocase subunit YajC
KOILJNNC_00847 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
KOILJNNC_00848 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KOILJNNC_00849 6.9e-19 yrzS S Protein of unknown function (DUF2905)
KOILJNNC_00850 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
KOILJNNC_00851 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
KOILJNNC_00852 4.8e-93 bofC S BofC C-terminal domain
KOILJNNC_00853 5.3e-253 csbX EGP Major facilitator Superfamily
KOILJNNC_00854 2.8e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
KOILJNNC_00855 7.2e-118 yrzF T serine threonine protein kinase
KOILJNNC_00857 8.1e-52 S Family of unknown function (DUF5412)
KOILJNNC_00859 4.5e-261 alsT E Sodium alanine symporter
KOILJNNC_00860 3.6e-126 yebC K transcriptional regulatory protein
KOILJNNC_00861 2.2e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KOILJNNC_00862 3.7e-149 safA M spore coat assembly protein SafA
KOILJNNC_00863 6.3e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KOILJNNC_00864 2.3e-156 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
KOILJNNC_00865 1.5e-297 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
KOILJNNC_00866 2e-227 nifS 2.8.1.7 E Cysteine desulfurase
KOILJNNC_00867 7.9e-94 niaR S small molecule binding protein (contains 3H domain)
KOILJNNC_00868 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
KOILJNNC_00869 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
KOILJNNC_00870 5.6e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KOILJNNC_00871 2.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
KOILJNNC_00872 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
KOILJNNC_00873 3.5e-55 ysxB J ribosomal protein
KOILJNNC_00874 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
KOILJNNC_00875 2.7e-160 spoIVFB S Stage IV sporulation protein
KOILJNNC_00876 4.2e-144 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
KOILJNNC_00877 2.5e-144 minD D Belongs to the ParA family
KOILJNNC_00878 3.5e-107 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
KOILJNNC_00879 1.4e-84 mreD M shape-determining protein
KOILJNNC_00880 1.1e-156 mreC M Involved in formation and maintenance of cell shape
KOILJNNC_00881 1.8e-184 mreB D Rod shape-determining protein MreB
KOILJNNC_00882 5.9e-126 radC E Belongs to the UPF0758 family
KOILJNNC_00883 8.3e-102 maf D septum formation protein Maf
KOILJNNC_00884 5.2e-160 spoIIB S Sporulation related domain
KOILJNNC_00885 1.5e-84 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
KOILJNNC_00886 4.7e-246 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
KOILJNNC_00887 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
KOILJNNC_00888 1.6e-25
KOILJNNC_00889 1.3e-198 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KOILJNNC_00890 4.4e-223 spoVID M stage VI sporulation protein D
KOILJNNC_00891 2.5e-247 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KOILJNNC_00892 8.1e-182 hemB 4.2.1.24 H Belongs to the ALAD family
KOILJNNC_00893 8.4e-145 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KOILJNNC_00894 1.1e-172 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
KOILJNNC_00895 3.6e-146 hemX O cytochrome C
KOILJNNC_00896 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KOILJNNC_00897 1.4e-89 ysxD
KOILJNNC_00898 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
KOILJNNC_00899 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KOILJNNC_00900 9.2e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
KOILJNNC_00901 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KOILJNNC_00902 4.1e-226 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
KOILJNNC_00903 8.6e-187 ysoA H Tetratricopeptide repeat
KOILJNNC_00904 4e-115 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOILJNNC_00905 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KOILJNNC_00906 5.7e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
KOILJNNC_00907 9.3e-289 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KOILJNNC_00908 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KOILJNNC_00909 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
KOILJNNC_00910 0.0 ilvB 2.2.1.6 E Acetolactate synthase
KOILJNNC_00912 8.2e-76 ysnE K acetyltransferase
KOILJNNC_00913 5.5e-131 ysnF S protein conserved in bacteria
KOILJNNC_00915 1.5e-91 ysnB S Phosphoesterase
KOILJNNC_00916 7.7e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KOILJNNC_00917 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KOILJNNC_00918 5e-196 gerM S COG5401 Spore germination protein
KOILJNNC_00919 4.3e-152 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
KOILJNNC_00920 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_00921 3.3e-30 gerE K Transcriptional regulator
KOILJNNC_00922 1.1e-77 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
KOILJNNC_00923 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KOILJNNC_00924 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
KOILJNNC_00925 2.4e-107 sdhC C succinate dehydrogenase
KOILJNNC_00926 1.2e-79 yslB S Protein of unknown function (DUF2507)
KOILJNNC_00927 3.1e-215 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KOILJNNC_00928 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
KOILJNNC_00929 2e-52 trxA O Belongs to the thioredoxin family
KOILJNNC_00930 1.4e-302 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
KOILJNNC_00931 1.1e-175 etfA C Electron transfer flavoprotein
KOILJNNC_00932 6.5e-134 etfB C Electron transfer flavoprotein
KOILJNNC_00933 3.5e-135 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
KOILJNNC_00934 1.1e-98 fadR K Transcriptional regulator
KOILJNNC_00935 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
KOILJNNC_00936 7.3e-68 yshE S membrane
KOILJNNC_00937 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
KOILJNNC_00938 0.0 polX L COG1796 DNA polymerase IV (family X)
KOILJNNC_00939 1.7e-85 cvpA S membrane protein, required for colicin V production
KOILJNNC_00940 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
KOILJNNC_00941 9e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOILJNNC_00942 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOILJNNC_00943 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KOILJNNC_00944 3.5e-132 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOILJNNC_00945 5.8e-32 sspI S Belongs to the SspI family
KOILJNNC_00946 4.9e-207 ysfB KT regulator
KOILJNNC_00947 3.7e-260 glcD 1.1.3.15 C Glycolate oxidase subunit
KOILJNNC_00948 4.7e-257 glcF C Glycolate oxidase
KOILJNNC_00949 2.8e-53 ysfE 4.4.1.5 E Glyoxalase-like domain
KOILJNNC_00950 0.0 cstA T Carbon starvation protein
KOILJNNC_00951 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
KOILJNNC_00952 3.8e-143 araQ G transport system permease
KOILJNNC_00953 1.4e-167 araP G carbohydrate transport
KOILJNNC_00954 1.7e-251 araN G carbohydrate transport
KOILJNNC_00955 3.1e-220 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
KOILJNNC_00956 6.6e-145 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
KOILJNNC_00957 1.9e-132 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
KOILJNNC_00958 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
KOILJNNC_00959 2.7e-293 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
KOILJNNC_00960 3.1e-189 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KOILJNNC_00961 5.8e-205 ysdC G COG1363 Cellulase M and related proteins
KOILJNNC_00962 9.2e-68 ysdB S Sigma-w pathway protein YsdB
KOILJNNC_00963 7.5e-45 ysdA S Membrane
KOILJNNC_00964 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KOILJNNC_00965 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
KOILJNNC_00966 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KOILJNNC_00968 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KOILJNNC_00969 3.1e-48 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
KOILJNNC_00970 3.1e-130 lytT T COG3279 Response regulator of the LytR AlgR family
KOILJNNC_00971 0.0 lytS 2.7.13.3 T Histidine kinase
KOILJNNC_00972 7.3e-149 ysaA S HAD-hyrolase-like
KOILJNNC_00973 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOILJNNC_00975 5.4e-158 ytxC S YtxC-like family
KOILJNNC_00976 2.7e-109 ytxB S SNARE associated Golgi protein
KOILJNNC_00977 9.5e-172 dnaI L Primosomal protein DnaI
KOILJNNC_00978 1.9e-264 dnaB L Membrane attachment protein
KOILJNNC_00979 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KOILJNNC_00980 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KOILJNNC_00981 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOILJNNC_00982 9.9e-67 ytcD K Transcriptional regulator
KOILJNNC_00983 1.6e-203 ytbD EGP Major facilitator Superfamily
KOILJNNC_00984 8.9e-161 ytbE S reductase
KOILJNNC_00985 4.9e-97 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KOILJNNC_00986 1.1e-107 ytaF P Probably functions as a manganese efflux pump
KOILJNNC_00987 1.1e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
KOILJNNC_00988 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KOILJNNC_00989 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
KOILJNNC_00990 4.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_00991 3.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
KOILJNNC_00992 4.1e-242 icd 1.1.1.42 C isocitrate
KOILJNNC_00993 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
KOILJNNC_00994 4.7e-71 yeaL S membrane
KOILJNNC_00995 2.6e-192 ytvI S sporulation integral membrane protein YtvI
KOILJNNC_00996 8.7e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
KOILJNNC_00997 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
KOILJNNC_00998 1.3e-179 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
KOILJNNC_00999 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
KOILJNNC_01000 2.4e-161 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KOILJNNC_01001 2e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
KOILJNNC_01002 0.0 dnaE 2.7.7.7 L DNA polymerase
KOILJNNC_01003 3.2e-56 ytrH S Sporulation protein YtrH
KOILJNNC_01004 8.2e-69 ytrI
KOILJNNC_01005 9.2e-29
KOILJNNC_01006 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
KOILJNNC_01007 2.4e-47 ytpI S YtpI-like protein
KOILJNNC_01008 8e-241 ytoI K transcriptional regulator containing CBS domains
KOILJNNC_01009 4.2e-156 ytnM S membrane transporter protein
KOILJNNC_01010 2.3e-237 ytnL 3.5.1.47 E hydrolase activity
KOILJNNC_01011 3.8e-125 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
KOILJNNC_01012 7.5e-255 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_01013 7.1e-46 ytnI O COG0695 Glutaredoxin and related proteins
KOILJNNC_01014 4.4e-183 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_01015 3.9e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KOILJNNC_01016 5.4e-119 tcyM U Binding-protein-dependent transport system inner membrane component
KOILJNNC_01017 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
KOILJNNC_01018 6.4e-148 tcyK M Bacterial periplasmic substrate-binding proteins
KOILJNNC_01019 1.8e-150 tcyK ET Bacterial periplasmic substrate-binding proteins
KOILJNNC_01020 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
KOILJNNC_01021 7.2e-172 ytlI K LysR substrate binding domain
KOILJNNC_01022 1.7e-130 ytkL S Belongs to the UPF0173 family
KOILJNNC_01023 1.6e-140 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_01025 2.2e-265 argH 4.3.2.1 E argininosuccinate lyase
KOILJNNC_01026 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
KOILJNNC_01027 1.4e-87 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
KOILJNNC_01028 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KOILJNNC_01029 3.5e-164 ytxK 2.1.1.72 L DNA methylase
KOILJNNC_01030 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KOILJNNC_01031 8.7e-70 ytfJ S Sporulation protein YtfJ
KOILJNNC_01032 5.6e-116 ytfI S Protein of unknown function (DUF2953)
KOILJNNC_01033 2.1e-85 yteJ S RDD family
KOILJNNC_01034 5.1e-179 sppA OU signal peptide peptidase SppA
KOILJNNC_01035 1.1e-147 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOILJNNC_01036 2.2e-311 ytcJ S amidohydrolase
KOILJNNC_01037 1.9e-305 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KOILJNNC_01038 2e-29 sspB S spore protein
KOILJNNC_01039 7.8e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KOILJNNC_01040 3.5e-208 iscS2 2.8.1.7 E Cysteine desulfurase
KOILJNNC_01041 9.3e-237 brnQ E Component of the transport system for branched-chain amino acids
KOILJNNC_01042 2e-273 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
KOILJNNC_01043 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
KOILJNNC_01044 1e-108 yttP K Transcriptional regulator
KOILJNNC_01045 4.5e-88 ytsP 1.8.4.14 T GAF domain-containing protein
KOILJNNC_01046 6.3e-310 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
KOILJNNC_01047 1.3e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KOILJNNC_01049 6.7e-237 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOILJNNC_01050 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
KOILJNNC_01051 8.9e-121 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
KOILJNNC_01052 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
KOILJNNC_01053 3.5e-224 acuC BQ histone deacetylase
KOILJNNC_01054 6.8e-125 motS N Flagellar motor protein
KOILJNNC_01055 6e-146 motA N flagellar motor
KOILJNNC_01056 1.7e-182 ccpA K catabolite control protein A
KOILJNNC_01057 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
KOILJNNC_01058 6.3e-54 ytxJ O Protein of unknown function (DUF2847)
KOILJNNC_01059 6.6e-17 ytxH S COG4980 Gas vesicle protein
KOILJNNC_01060 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
KOILJNNC_01061 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
KOILJNNC_01062 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
KOILJNNC_01063 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
KOILJNNC_01064 9.8e-149 ytpQ S Belongs to the UPF0354 family
KOILJNNC_01065 1.3e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KOILJNNC_01066 1.7e-78 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
KOILJNNC_01067 4e-206 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
KOILJNNC_01068 2.2e-51 ytzB S small secreted protein
KOILJNNC_01069 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
KOILJNNC_01070 7.1e-150 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
KOILJNNC_01071 2.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
KOILJNNC_01072 2e-45 ytzH S YtzH-like protein
KOILJNNC_01073 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
KOILJNNC_01074 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
KOILJNNC_01075 3.3e-180 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
KOILJNNC_01076 1.3e-165 ytlQ
KOILJNNC_01077 4.4e-100 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KOILJNNC_01078 3.3e-172 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOILJNNC_01079 3e-270 pepV 3.5.1.18 E Dipeptidase
KOILJNNC_01080 7.2e-226 pbuO S permease
KOILJNNC_01081 7.6e-203 ythQ U Bacterial ABC transporter protein EcsB
KOILJNNC_01082 1.8e-130 ythP V ABC transporter
KOILJNNC_01083 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
KOILJNNC_01084 1.3e-131 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
KOILJNNC_01085 2.1e-280 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_01086 1.8e-231 ytfP S HI0933-like protein
KOILJNNC_01087 1.3e-282 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
KOILJNNC_01088 3.1e-26 yteV S Sporulation protein Cse60
KOILJNNC_01089 5.3e-116 yteU S Integral membrane protein
KOILJNNC_01090 3.9e-256 yteT S Oxidoreductase family, C-terminal alpha/beta domain
KOILJNNC_01091 4.6e-73 yteS G transport
KOILJNNC_01092 2.3e-217 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
KOILJNNC_01093 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KOILJNNC_01094 0.0 ytdP K Transcriptional regulator
KOILJNNC_01095 1.2e-288 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
KOILJNNC_01096 2e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
KOILJNNC_01097 2.8e-137 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
KOILJNNC_01098 9.8e-222 bioI 1.14.14.46 C Cytochrome P450
KOILJNNC_01099 1.2e-188 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KOILJNNC_01100 1.9e-124 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KOILJNNC_01101 3e-215 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KOILJNNC_01102 1e-259 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
KOILJNNC_01103 8.1e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
KOILJNNC_01104 7.8e-171 ytaP S Acetyl xylan esterase (AXE1)
KOILJNNC_01105 1.5e-189 msmR K Transcriptional regulator
KOILJNNC_01106 3.4e-244 msmE G Bacterial extracellular solute-binding protein
KOILJNNC_01107 2.4e-167 amyD P ABC transporter
KOILJNNC_01108 1.7e-143 amyC P ABC transporter (permease)
KOILJNNC_01109 3.4e-252 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KOILJNNC_01110 2.1e-51 ytwF P Sulfurtransferase
KOILJNNC_01111 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOILJNNC_01112 7.7e-55 ytvB S Protein of unknown function (DUF4257)
KOILJNNC_01113 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
KOILJNNC_01114 1.7e-210 yttB EGP Major facilitator Superfamily
KOILJNNC_01115 9.7e-42 yttA 2.7.13.3 S Pfam Transposase IS66
KOILJNNC_01116 0.0 bceB V ABC transporter (permease)
KOILJNNC_01117 7.3e-138 bceA V ABC transporter, ATP-binding protein
KOILJNNC_01118 8.9e-184 T PhoQ Sensor
KOILJNNC_01119 5.1e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_01120 2.3e-232 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
KOILJNNC_01121 9.1e-127 ytrE V ABC transporter, ATP-binding protein
KOILJNNC_01122 2.6e-148
KOILJNNC_01123 1e-152 P ABC-2 family transporter protein
KOILJNNC_01124 7.1e-161 ytrB P abc transporter atp-binding protein
KOILJNNC_01125 5.1e-66 ytrA K GntR family transcriptional regulator
KOILJNNC_01127 6.7e-41 ytzC S Protein of unknown function (DUF2524)
KOILJNNC_01128 8.1e-190 yhcC S Fe-S oxidoreductase
KOILJNNC_01129 9.7e-106 ytqB J Putative rRNA methylase
KOILJNNC_01130 2.8e-215 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
KOILJNNC_01131 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
KOILJNNC_01132 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KOILJNNC_01133 2.4e-256 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_01134 0.0 asnB 6.3.5.4 E Asparagine synthase
KOILJNNC_01135 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KOILJNNC_01136 8.8e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KOILJNNC_01137 1.2e-38 ytmB S Protein of unknown function (DUF2584)
KOILJNNC_01138 2e-146 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
KOILJNNC_01139 9.5e-189 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
KOILJNNC_01140 1.4e-144 ytlC P ABC transporter
KOILJNNC_01141 6.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KOILJNNC_01142 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
KOILJNNC_01143 7.8e-62 ytkC S Bacteriophage holin family
KOILJNNC_01144 2.1e-76 dps P Belongs to the Dps family
KOILJNNC_01146 2.2e-70 ytkA S YtkA-like
KOILJNNC_01147 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
KOILJNNC_01148 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KOILJNNC_01149 6.1e-41 rpmE2 J Ribosomal protein L31
KOILJNNC_01150 1.1e-248 cydA 1.10.3.14 C oxidase, subunit
KOILJNNC_01151 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
KOILJNNC_01152 1.1e-24 S Domain of Unknown Function (DUF1540)
KOILJNNC_01153 1.5e-150 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
KOILJNNC_01154 1.5e-231 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KOILJNNC_01155 1.2e-137 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KOILJNNC_01156 1.1e-169 troA P Belongs to the bacterial solute-binding protein 9 family
KOILJNNC_01157 5.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
KOILJNNC_01158 3.7e-271 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
KOILJNNC_01159 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
KOILJNNC_01160 4.3e-152 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
KOILJNNC_01161 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KOILJNNC_01162 1.9e-272 menF 5.4.4.2 HQ Isochorismate synthase
KOILJNNC_01163 2.6e-132 dksA T COG1734 DnaK suppressor protein
KOILJNNC_01164 2.3e-153 galU 2.7.7.9 M Nucleotidyl transferase
KOILJNNC_01165 4.4e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KOILJNNC_01166 1.1e-178 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
KOILJNNC_01167 3.3e-233 ytcC M Glycosyltransferase Family 4
KOILJNNC_01169 2.5e-205 cotS S Seems to be required for the assembly of the CotSA protein in spores
KOILJNNC_01170 3.1e-217 cotSA M Glycosyl transferases group 1
KOILJNNC_01171 1.8e-203 cotI S Spore coat protein
KOILJNNC_01172 2.9e-76 tspO T membrane
KOILJNNC_01173 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
KOILJNNC_01174 1.1e-286 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
KOILJNNC_01175 2.9e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
KOILJNNC_01176 6.1e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KOILJNNC_01177 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
KOILJNNC_01186 7.8e-08
KOILJNNC_01187 1.3e-09
KOILJNNC_01194 2e-08
KOILJNNC_01199 2e-08
KOILJNNC_01204 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOILJNNC_01205 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KOILJNNC_01206 1.8e-37 yaaB S Domain of unknown function (DUF370)
KOILJNNC_01207 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KOILJNNC_01208 2.4e-33 yaaA S S4 domain
KOILJNNC_01209 1.8e-204 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
KOILJNNC_01210 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KOILJNNC_01211 6.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
KOILJNNC_01212 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
KOILJNNC_01213 3.2e-107 jag S single-stranded nucleic acid binding R3H
KOILJNNC_01214 1.3e-249 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KOILJNNC_01215 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
KOILJNNC_01216 1.4e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
KOILJNNC_01217 2.7e-149 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
KOILJNNC_01218 9.6e-74 S Bacterial PH domain
KOILJNNC_01219 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
KOILJNNC_01220 2.1e-149 spo0J K Belongs to the ParB family
KOILJNNC_01221 1.6e-111 yyaC S Sporulation protein YyaC
KOILJNNC_01222 8.1e-177 yyaD S Membrane
KOILJNNC_01223 2.3e-33 yyzM S protein conserved in bacteria
KOILJNNC_01224 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KOILJNNC_01225 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
KOILJNNC_01226 2.1e-45 rpsF J Binds together with S18 to 16S ribosomal RNA
KOILJNNC_01227 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
KOILJNNC_01228 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KOILJNNC_01229 5.8e-143 xth 3.1.11.2 L exodeoxyribonuclease III
KOILJNNC_01230 2.9e-176 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
KOILJNNC_01231 8.4e-66 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_01232 2.8e-94 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
KOILJNNC_01233 5.7e-242 EGP Major facilitator superfamily
KOILJNNC_01234 3.4e-166 yyaK S CAAX protease self-immunity
KOILJNNC_01235 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
KOILJNNC_01237 2.1e-92 yyaS S Membrane
KOILJNNC_01238 5e-70 yjcF S Acetyltransferase (GNAT) domain
KOILJNNC_01239 5.6e-77 yybA 2.3.1.57 K transcriptional
KOILJNNC_01240 1.4e-124 S Metallo-beta-lactamase superfamily
KOILJNNC_01241 2.8e-74 yybC
KOILJNNC_01242 2e-79 yjcF S Acetyltransferase (GNAT) domain
KOILJNNC_01243 4.5e-163 yybE K Transcriptional regulator
KOILJNNC_01244 1e-188 ynfM EGP Major facilitator Superfamily
KOILJNNC_01245 1.6e-122 yybG S Pentapeptide repeat-containing protein
KOILJNNC_01246 2.9e-66 yybH S SnoaL-like domain
KOILJNNC_01247 1.8e-123
KOILJNNC_01248 3.1e-109 K TipAS antibiotic-recognition domain
KOILJNNC_01249 1.8e-240 yybO G COG0477 Permeases of the major facilitator superfamily
KOILJNNC_01251 1.2e-58
KOILJNNC_01252 5.6e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
KOILJNNC_01253 1.7e-66 ydeP3 K Transcriptional regulator
KOILJNNC_01254 3.9e-84 cotF M Spore coat protein
KOILJNNC_01256 1.4e-159 yybS S membrane
KOILJNNC_01257 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
KOILJNNC_01258 2.2e-73 rplI J binds to the 23S rRNA
KOILJNNC_01259 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOILJNNC_01260 2.1e-219 yeaN P COG2807 Cyanate permease
KOILJNNC_01261 1.9e-15 yycC K YycC-like protein
KOILJNNC_01263 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
KOILJNNC_01264 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
KOILJNNC_01265 8.9e-77 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_01266 3e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KOILJNNC_01271 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_01272 0.0 vicK 2.7.13.3 T Histidine kinase
KOILJNNC_01273 1.9e-256 yycH S protein conserved in bacteria
KOILJNNC_01274 7.3e-155 yycI S protein conserved in bacteria
KOILJNNC_01275 1.9e-149 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
KOILJNNC_01276 1.9e-217 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KOILJNNC_01277 1.6e-32 S Peptidase propeptide and YPEB domain
KOILJNNC_01278 4e-74 S Peptidase propeptide and YPEB domain
KOILJNNC_01279 1.5e-94 K PFAM response regulator receiver
KOILJNNC_01280 5.1e-172 phoR3 2.7.13.3 T COG0642 Signal transduction histidine kinase
KOILJNNC_01281 9.9e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
KOILJNNC_01282 2.1e-232 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
KOILJNNC_01283 7.8e-261 rocE E amino acid
KOILJNNC_01284 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
KOILJNNC_01286 8.5e-188 S aspartate phosphatase
KOILJNNC_01287 5.8e-85 yycN 2.3.1.128 K Acetyltransferase
KOILJNNC_01288 3.8e-131 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KOILJNNC_01289 5.1e-207 yycP
KOILJNNC_01290 1.7e-30 yycQ S Protein of unknown function (DUF2651)
KOILJNNC_01292 4.3e-233 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
KOILJNNC_01293 4.4e-68
KOILJNNC_01294 1.1e-09 S YyzF-like protein
KOILJNNC_01295 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KOILJNNC_01296 2.1e-81 uxuA 4.2.1.8 S AIPR protein
KOILJNNC_01297 2.8e-104 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
KOILJNNC_01298 1e-13 2.7.7.9 K Helix-turn-helix XRE-family like proteins
KOILJNNC_01299 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
KOILJNNC_01300 1.6e-109 prrC P ABC transporter
KOILJNNC_01301 3.6e-118 S ABC-2 family transporter protein
KOILJNNC_01302 2.2e-12
KOILJNNC_01303 5.6e-124 yydK K Transcriptional regulator
KOILJNNC_01304 2.4e-19 bglF G phosphotransferase system
KOILJNNC_01305 5.4e-291 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOILJNNC_01306 8.1e-188 wgaE S Polysaccharide pyruvyl transferase
KOILJNNC_01307 1.2e-285 ahpF O Alkyl hydroperoxide reductase
KOILJNNC_01308 3.6e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
KOILJNNC_01309 4.2e-272 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KOILJNNC_01310 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
KOILJNNC_01311 1.5e-302 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
KOILJNNC_01312 2.1e-126 gntR K transcriptional
KOILJNNC_01313 2.3e-204 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
KOILJNNC_01314 6.3e-193 yxaB GM Polysaccharide pyruvyl transferase
KOILJNNC_01315 2.6e-118 yxaC M effector of murein hydrolase
KOILJNNC_01316 5.2e-50 S LrgA family
KOILJNNC_01317 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_01318 4.4e-197 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_01319 2.7e-100 yxaF K Transcriptional regulator
KOILJNNC_01320 3.5e-196 yxaG 1.13.11.24 S AraC-like ligand binding domain
KOILJNNC_01321 7.9e-227 P Protein of unknown function (DUF418)
KOILJNNC_01322 1.4e-75 yxaI S membrane protein domain
KOILJNNC_01323 1.1e-63 S Family of unknown function (DUF5391)
KOILJNNC_01324 2.2e-91 S PQQ-like domain
KOILJNNC_01325 4.8e-31 yxaI S membrane protein domain
KOILJNNC_01326 2.7e-244 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KOILJNNC_01327 6.2e-197 yxbF K Bacterial regulatory proteins, tetR family
KOILJNNC_01328 1.1e-150 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_01330 0.0 htpG O Molecular chaperone. Has ATPase activity
KOILJNNC_01331 1.1e-245 csbC EGP Major facilitator Superfamily
KOILJNNC_01332 8.9e-79 T HPP family
KOILJNNC_01333 1.9e-90 S CGNR zinc finger
KOILJNNC_01334 8.3e-48 yxcD S Protein of unknown function (DUF2653)
KOILJNNC_01336 3.2e-175 iolS C Aldo keto reductase
KOILJNNC_01337 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
KOILJNNC_01338 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KOILJNNC_01339 7.8e-154 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
KOILJNNC_01340 3.9e-176 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
KOILJNNC_01341 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
KOILJNNC_01342 1e-175 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
KOILJNNC_01343 1.6e-233 iolF EGP Major facilitator Superfamily
KOILJNNC_01344 1e-195 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
KOILJNNC_01345 3e-167 iolH G Xylose isomerase-like TIM barrel
KOILJNNC_01346 3.3e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
KOILJNNC_01347 7.8e-160 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
KOILJNNC_01348 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_01349 1.3e-179 T PhoQ Sensor
KOILJNNC_01350 2.6e-138 yxdL V ABC transporter, ATP-binding protein
KOILJNNC_01351 0.0 yxdM V ABC transporter (permease)
KOILJNNC_01352 1.3e-57 yxeA S Protein of unknown function (DUF1093)
KOILJNNC_01353 1.9e-175 fhuD P ABC transporter
KOILJNNC_01354 8.5e-69
KOILJNNC_01355 5.6e-16 yxeD
KOILJNNC_01356 2.5e-14 yxeE
KOILJNNC_01359 4.9e-148 yidA S hydrolases of the HAD superfamily
KOILJNNC_01360 2.4e-189 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
KOILJNNC_01361 7e-253 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_01362 8.9e-92 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_01363 2.1e-143 yxeM M Belongs to the bacterial solute-binding protein 3 family
KOILJNNC_01364 1.6e-107 yxeN P COG0765 ABC-type amino acid transport system, permease component
KOILJNNC_01365 1.7e-131 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
KOILJNNC_01366 4.7e-213 yxeP 3.5.1.47 E hydrolase activity
KOILJNNC_01367 2.8e-249 yxeQ S MmgE/PrpD family
KOILJNNC_01368 1e-196 eutH E Ethanolamine utilisation protein, EutH
KOILJNNC_01369 2e-152 yxxB S Domain of Unknown Function (DUF1206)
KOILJNNC_01372 1.2e-72 V ATPases associated with a variety of cellular activities
KOILJNNC_01374 9.7e-72
KOILJNNC_01375 1.6e-28
KOILJNNC_01376 2.4e-27 KT COG4219 Antirepressor regulating drug resistance
KOILJNNC_01377 7.9e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KOILJNNC_01378 7.7e-115 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KOILJNNC_01379 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KOILJNNC_01380 3e-232 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
KOILJNNC_01381 4.8e-249 lysP E amino acid
KOILJNNC_01382 1.5e-180 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
KOILJNNC_01383 7e-234 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
KOILJNNC_01384 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KOILJNNC_01385 3.4e-283 hutH 4.3.1.3 E Histidine ammonia-lyase
KOILJNNC_01386 1.1e-77 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
KOILJNNC_01387 2.4e-275 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
KOILJNNC_01389 2.2e-179 L AlwI restriction endonuclease
KOILJNNC_01390 3.7e-183 2.1.1.37 H C-5 cytosine-specific DNA methylase
KOILJNNC_01391 6.1e-49 vsr L May nick specific sequences that contain T G mispairs resulting from m5C-deamination
KOILJNNC_01392 2.3e-20 S Domain of unknown function (DUF5082)
KOILJNNC_01393 1.4e-38 yxiC S Family of unknown function (DUF5344)
KOILJNNC_01394 1.4e-215 S nuclease activity
KOILJNNC_01395 2e-55
KOILJNNC_01396 1.7e-30
KOILJNNC_01397 1.3e-24
KOILJNNC_01398 4.3e-54
KOILJNNC_01399 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_01400 4e-278 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOILJNNC_01401 5.4e-72 yxiE T Belongs to the universal stress protein A family
KOILJNNC_01402 3.9e-165 yxxF EG EamA-like transporter family
KOILJNNC_01403 3.3e-83 yxiI S Protein of unknown function (DUF2716)
KOILJNNC_01404 3.5e-43 yxiJ S YxiJ-like protein
KOILJNNC_01407 1.3e-61 S Protein of unknown function (DUF2812)
KOILJNNC_01408 6.1e-52 padR K Transcriptional regulator PadR-like family
KOILJNNC_01409 8e-213 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
KOILJNNC_01410 1.6e-263 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
KOILJNNC_01411 9.5e-231 yxiO S COG2270 Permeases of the major facilitator superfamily
KOILJNNC_01412 2e-110
KOILJNNC_01413 8.3e-151 licT K transcriptional antiterminator
KOILJNNC_01414 3.3e-143 exoK GH16 M licheninase activity
KOILJNNC_01415 3.3e-223 citH C Citrate transporter
KOILJNNC_01416 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
KOILJNNC_01417 5.6e-46 yxiS
KOILJNNC_01418 5.2e-103 T Domain of unknown function (DUF4163)
KOILJNNC_01419 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KOILJNNC_01420 7.9e-157 rlmA 2.1.1.187 Q Methyltransferase domain
KOILJNNC_01421 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
KOILJNNC_01422 1.8e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KOILJNNC_01423 2e-115 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
KOILJNNC_01424 4.8e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
KOILJNNC_01425 2.2e-218 yxjG 2.1.1.14 E Methionine synthase
KOILJNNC_01426 5.7e-219 yxjG 2.1.1.14 E Methionine synthase
KOILJNNC_01427 6.7e-84 yxjI S LURP-one-related
KOILJNNC_01430 1e-234 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
KOILJNNC_01431 3.7e-114 K helix_turn_helix, Lux Regulon
KOILJNNC_01432 5.6e-188 yxjM T Signal transduction histidine kinase
KOILJNNC_01433 5.5e-75 S Protein of unknown function (DUF1453)
KOILJNNC_01434 6.7e-195 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
KOILJNNC_01435 2.8e-74 yxkC S Domain of unknown function (DUF4352)
KOILJNNC_01436 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOILJNNC_01437 1.6e-274 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KOILJNNC_01438 1.7e-162 lrp QT PucR C-terminal helix-turn-helix domain
KOILJNNC_01439 5.9e-205 msmK P Belongs to the ABC transporter superfamily
KOILJNNC_01440 6.8e-153 yxkH G Polysaccharide deacetylase
KOILJNNC_01442 1e-309 3.4.24.84 O Peptidase family M48
KOILJNNC_01443 1.5e-229 cimH C COG3493 Na citrate symporter
KOILJNNC_01444 3.1e-267 cydA 1.10.3.14 C oxidase, subunit
KOILJNNC_01445 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
KOILJNNC_01446 0.0 cydD V ATP-binding
KOILJNNC_01447 0.0 cydD V ATP-binding protein
KOILJNNC_01448 4.8e-159 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KOILJNNC_01449 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
KOILJNNC_01450 1.1e-90 sigY K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_01451 3.9e-48 yxlC S Family of unknown function (DUF5345)
KOILJNNC_01452 1.4e-30
KOILJNNC_01453 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
KOILJNNC_01454 9.7e-166 yxlF V ABC transporter, ATP-binding protein
KOILJNNC_01455 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KOILJNNC_01456 4.6e-211 yxlH EGP Major facilitator Superfamily
KOILJNNC_01457 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KOILJNNC_01458 5e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
KOILJNNC_01459 1.1e-19 yxzF
KOILJNNC_01460 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
KOILJNNC_01461 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
KOILJNNC_01462 2e-247 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOILJNNC_01463 8.7e-51 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
KOILJNNC_01464 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KOILJNNC_01465 6.9e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KOILJNNC_01466 4.7e-137 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_01467 6.7e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
KOILJNNC_01468 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_01469 1.2e-232 dltB M membrane protein involved in D-alanine export
KOILJNNC_01470 3.3e-291 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_01471 5.1e-15 S D-Ala-teichoic acid biosynthesis protein
KOILJNNC_01472 2.3e-165 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
KOILJNNC_01473 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
KOILJNNC_01474 3e-130 ynfM EGP Major facilitator Superfamily
KOILJNNC_01475 5.5e-49 4.1.1.44 S Carboxymuconolactone decarboxylase family
KOILJNNC_01476 1.4e-92 K Helix-turn-helix XRE-family like proteins
KOILJNNC_01477 2.6e-250 ywaD 3.4.11.10, 3.4.11.6 S PA domain
KOILJNNC_01478 3.9e-229 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KOILJNNC_01479 4e-87 ywaE K Transcriptional regulator
KOILJNNC_01480 6.7e-125 ywaF S Integral membrane protein
KOILJNNC_01481 4.5e-168 gspA M General stress
KOILJNNC_01482 1.5e-152 sacY K transcriptional antiterminator
KOILJNNC_01483 2e-242 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_01484 3.7e-271 epr 3.4.21.62 O Belongs to the peptidase S8 family
KOILJNNC_01485 3.5e-244 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOILJNNC_01486 9.5e-121 ywbB S Protein of unknown function (DUF2711)
KOILJNNC_01487 9.9e-67 ywbC 4.4.1.5 E glyoxalase
KOILJNNC_01488 2e-219 ywbD 2.1.1.191 J Methyltransferase
KOILJNNC_01489 2.3e-27 ywbE S Uncharacterized conserved protein (DUF2196)
KOILJNNC_01490 1.3e-208 ywbF EGP Major facilitator Superfamily
KOILJNNC_01491 2.3e-111 ywbG M effector of murein hydrolase
KOILJNNC_01492 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
KOILJNNC_01493 1.6e-152 ywbI K Transcriptional regulator
KOILJNNC_01494 1.1e-142 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
KOILJNNC_01495 6.5e-114 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
KOILJNNC_01496 6.1e-250 P COG0672 High-affinity Fe2 Pb2 permease
KOILJNNC_01497 4.2e-185 ycdO P periplasmic lipoprotein involved in iron transport
KOILJNNC_01498 4.2e-223 ywbN P Dyp-type peroxidase family protein
KOILJNNC_01499 3.6e-111 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KOILJNNC_01500 9e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOILJNNC_01501 9.8e-49 ywcB S Protein of unknown function, DUF485
KOILJNNC_01503 1.1e-121 ywcC K transcriptional regulator
KOILJNNC_01504 9.5e-60 gtcA S GtrA-like protein
KOILJNNC_01505 3.8e-226 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KOILJNNC_01506 7.5e-299 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
KOILJNNC_01507 1e-35 ywzA S membrane
KOILJNNC_01508 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
KOILJNNC_01509 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KOILJNNC_01510 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KOILJNNC_01511 5.9e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
KOILJNNC_01512 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
KOILJNNC_01513 8.6e-202 rodA D Belongs to the SEDS family
KOILJNNC_01514 2.1e-137 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
KOILJNNC_01515 7.3e-186 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_01516 0.0 vpr O Belongs to the peptidase S8 family
KOILJNNC_01518 7e-150 sacT K transcriptional antiterminator
KOILJNNC_01519 2.6e-138 focA P Formate/nitrite transporter
KOILJNNC_01520 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_01521 4.6e-290 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
KOILJNNC_01522 2e-28 ywdA
KOILJNNC_01523 3.5e-146 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KOILJNNC_01524 1.3e-57 pex K Transcriptional regulator PadR-like family
KOILJNNC_01525 4.9e-111 ywdD
KOILJNNC_01527 5.5e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
KOILJNNC_01528 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KOILJNNC_01529 4e-259 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
KOILJNNC_01530 1.3e-48 ywdI S Family of unknown function (DUF5327)
KOILJNNC_01531 1.1e-237 ywdJ F Xanthine uracil
KOILJNNC_01532 4.3e-59 ywdK S small membrane protein
KOILJNNC_01533 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
KOILJNNC_01534 2.4e-144 spsA M Spore Coat
KOILJNNC_01535 4.3e-269 spsB M Capsule polysaccharide biosynthesis protein
KOILJNNC_01536 1.3e-223 spsC E Belongs to the DegT DnrJ EryC1 family
KOILJNNC_01537 1.7e-162 spsD 2.3.1.210 K Spore Coat
KOILJNNC_01538 3.5e-213 spsE 2.5.1.56 M acid synthase
KOILJNNC_01539 9.7e-132 spsF M Spore Coat
KOILJNNC_01540 2.3e-187 spsG M Spore Coat
KOILJNNC_01541 3.2e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KOILJNNC_01542 2.5e-180 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
KOILJNNC_01543 1.1e-158 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
KOILJNNC_01544 1.3e-86 spsL 5.1.3.13 M Spore Coat
KOILJNNC_01545 1.2e-77
KOILJNNC_01546 1.3e-243 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
KOILJNNC_01547 4.1e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KOILJNNC_01548 0.0 rocB E arginine degradation protein
KOILJNNC_01549 2.8e-249 lysP E amino acid
KOILJNNC_01550 6e-206 ywfA EGP Major facilitator Superfamily
KOILJNNC_01551 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
KOILJNNC_01552 2.9e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
KOILJNNC_01553 1.3e-137 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_01554 8e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
KOILJNNC_01555 1.9e-209 bacE EGP Major facilitator Superfamily
KOILJNNC_01556 2.1e-232 ywfG 2.6.1.83 E Aminotransferase class I and II
KOILJNNC_01557 3.4e-138 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_01558 2.1e-145 ywfI C May function as heme-dependent peroxidase
KOILJNNC_01559 5.6e-175 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
KOILJNNC_01560 7.1e-156 cysL K Transcriptional regulator
KOILJNNC_01561 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
KOILJNNC_01562 2.2e-157 ywfM EG EamA-like transporter family
KOILJNNC_01563 1e-110 rsfA_1
KOILJNNC_01564 3.1e-36 ywzC S Belongs to the UPF0741 family
KOILJNNC_01565 1.1e-255 ywfO S COG1078 HD superfamily phosphohydrolases
KOILJNNC_01566 2.7e-88 ywgA 2.1.1.72, 3.1.21.3
KOILJNNC_01567 6.2e-79 yffB K Transcriptional regulator
KOILJNNC_01568 6.8e-238 mmr U Major Facilitator Superfamily
KOILJNNC_01570 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KOILJNNC_01571 3.3e-71 ywhA K Transcriptional regulator
KOILJNNC_01572 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
KOILJNNC_01573 5.1e-119 ywhC S Peptidase family M50
KOILJNNC_01574 2e-94 ywhD S YwhD family
KOILJNNC_01575 1e-10
KOILJNNC_01576 4.7e-15 3.4.16.4 V Beta-lactamase class C and other penicillin binding proteins
KOILJNNC_01577 2.6e-143 bla 3.5.2.6 V beta-lactamase
KOILJNNC_01578 3.8e-81 S Putative sensor
KOILJNNC_01579 0.0 yvfT T helix_turn_helix, Lux Regulon
KOILJNNC_01580 9.6e-24 V Beta-lactamase
KOILJNNC_01581 0.0 V Beta-lactamase
KOILJNNC_01582 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOILJNNC_01583 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KOILJNNC_01584 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
KOILJNNC_01585 9.5e-28 ywhH S Aminoacyl-tRNA editing domain
KOILJNNC_01587 3.1e-79 S aspartate phosphatase
KOILJNNC_01588 5.2e-195 ywhK CO amine dehydrogenase activity
KOILJNNC_01589 9.9e-242 ywhL CO amine dehydrogenase activity
KOILJNNC_01591 1e-245 L Peptidase, M16
KOILJNNC_01592 3.2e-217 2.7.1.26, 2.7.7.2 L Peptidase, M16
KOILJNNC_01593 8e-233 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
KOILJNNC_01594 2.8e-131 cbiO V ABC transporter
KOILJNNC_01596 1.3e-270 C Fe-S oxidoreductases
KOILJNNC_01597 1e-07 S Bacteriocin subtilosin A
KOILJNNC_01598 4.7e-73 ywiB S protein conserved in bacteria
KOILJNNC_01599 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
KOILJNNC_01600 1.3e-213 narK P COG2223 Nitrate nitrite transporter
KOILJNNC_01601 2e-129 fnr K helix_turn_helix, cAMP Regulatory protein
KOILJNNC_01602 1.7e-139 ywiC S YwiC-like protein
KOILJNNC_01603 7e-86 arfM T cyclic nucleotide binding
KOILJNNC_01604 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KOILJNNC_01605 1.5e-296 narH 1.7.5.1 C Nitrate reductase, beta
KOILJNNC_01606 1.1e-93 narJ 1.7.5.1 C nitrate reductase
KOILJNNC_01607 2.6e-123 narI 1.7.5.1 C nitrate reductase, gamma
KOILJNNC_01608 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOILJNNC_01609 0.0 ywjA V ABC transporter
KOILJNNC_01610 2.5e-92 ywjB H RibD C-terminal domain
KOILJNNC_01611 2.7e-42 ywjC
KOILJNNC_01612 2.5e-183 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
KOILJNNC_01613 9.9e-222 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
KOILJNNC_01614 0.0 fadF C COG0247 Fe-S oxidoreductase
KOILJNNC_01615 8.2e-210 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
KOILJNNC_01616 4.8e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
KOILJNNC_01617 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
KOILJNNC_01618 5.1e-90 ywjG S Domain of unknown function (DUF2529)
KOILJNNC_01619 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
KOILJNNC_01620 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
KOILJNNC_01621 1.3e-111 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KOILJNNC_01622 1.9e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOILJNNC_01623 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
KOILJNNC_01624 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KOILJNNC_01625 1.1e-32 rpmE J Binds the 23S rRNA
KOILJNNC_01626 7e-104 tdk 2.7.1.21 F thymidine kinase
KOILJNNC_01627 0.0 sfcA 1.1.1.38 C malic enzyme
KOILJNNC_01628 8.6e-160 ywkB S Membrane transport protein
KOILJNNC_01629 7.1e-90 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
KOILJNNC_01630 1.2e-67 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_01631 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KOILJNNC_01632 6.6e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
KOILJNNC_01634 9.8e-56 ywlA S Uncharacterised protein family (UPF0715)
KOILJNNC_01635 6.1e-112 spoIIR S stage II sporulation protein R
KOILJNNC_01636 2.1e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
KOILJNNC_01637 7.6e-194 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
KOILJNNC_01638 1.7e-91 mntP P Probably functions as a manganese efflux pump
KOILJNNC_01639 1.3e-76 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOILJNNC_01640 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
KOILJNNC_01641 7.2e-95 ywlG S Belongs to the UPF0340 family
KOILJNNC_01642 4.6e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KOILJNNC_01643 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KOILJNNC_01644 2.5e-62 atpI S ATP synthase
KOILJNNC_01645 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
KOILJNNC_01646 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOILJNNC_01647 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KOILJNNC_01648 1.7e-88 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KOILJNNC_01649 1e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KOILJNNC_01650 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KOILJNNC_01651 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KOILJNNC_01652 8.5e-53 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
KOILJNNC_01653 4.8e-87 ywmA
KOILJNNC_01654 1.3e-32 ywzB S membrane
KOILJNNC_01655 5e-131 ywmB S TATA-box binding
KOILJNNC_01656 4.7e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KOILJNNC_01657 2.9e-177 spoIID D Stage II sporulation protein D
KOILJNNC_01658 5.1e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
KOILJNNC_01659 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
KOILJNNC_01661 9.9e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KOILJNNC_01662 3.5e-191 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KOILJNNC_01663 7.9e-104 S response regulator aspartate phosphatase
KOILJNNC_01664 3e-84 ywmF S Peptidase M50
KOILJNNC_01665 3.2e-10 csbD K CsbD-like
KOILJNNC_01666 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
KOILJNNC_01667 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
KOILJNNC_01668 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
KOILJNNC_01669 1.7e-64 ywnA K Transcriptional regulator
KOILJNNC_01670 1.1e-113 ywnB S NAD(P)H-binding
KOILJNNC_01671 1.7e-58 ywnC S Family of unknown function (DUF5362)
KOILJNNC_01672 5.3e-144 mta K transcriptional
KOILJNNC_01673 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KOILJNNC_01674 2.9e-70 ywnF S Family of unknown function (DUF5392)
KOILJNNC_01675 8.6e-13 ywnC S Family of unknown function (DUF5362)
KOILJNNC_01676 2.7e-88 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
KOILJNNC_01677 2.6e-115 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
KOILJNNC_01678 3.9e-72 ywnJ S VanZ like family
KOILJNNC_01679 1.3e-102 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
KOILJNNC_01680 1.6e-58 nrgB K Belongs to the P(II) protein family
KOILJNNC_01681 3.3e-225 amt P Ammonium transporter
KOILJNNC_01682 1.4e-75
KOILJNNC_01683 7.5e-103 phzA Q Isochorismatase family
KOILJNNC_01684 1.8e-240 ywoD EGP Major facilitator superfamily
KOILJNNC_01685 1.1e-278 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
KOILJNNC_01686 3e-230 ywoF P Right handed beta helix region
KOILJNNC_01688 2.7e-211 ywoG EGP Major facilitator Superfamily
KOILJNNC_01689 2.1e-70 ywoH K COG1846 Transcriptional regulators
KOILJNNC_01690 3e-44 spoIIID K Stage III sporulation protein D
KOILJNNC_01691 3.5e-180 mbl D Rod shape-determining protein
KOILJNNC_01692 6.4e-124 flhO N flagellar basal body
KOILJNNC_01693 8.3e-140 flhP N flagellar basal body
KOILJNNC_01694 2.8e-196 S aspartate phosphatase
KOILJNNC_01695 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
KOILJNNC_01696 3.9e-50 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
KOILJNNC_01697 0.0 ywpD T PhoQ Sensor
KOILJNNC_01698 9e-174 M1-574 T Transcriptional regulatory protein, C terminal
KOILJNNC_01699 0.0 M1-568 M cell wall anchor domain
KOILJNNC_01700 3e-84 srtA 3.4.22.70 M Sortase family
KOILJNNC_01701 1.1e-66 ywpF S YwpF-like protein
KOILJNNC_01702 3.8e-66 ywpG
KOILJNNC_01703 1.4e-56 ssbB L Single-stranded DNA-binding protein
KOILJNNC_01704 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
KOILJNNC_01705 3.9e-156 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
KOILJNNC_01706 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
KOILJNNC_01707 4.2e-308 ywqB S SWIM zinc finger
KOILJNNC_01708 1.2e-17
KOILJNNC_01709 2e-116 ywqC M biosynthesis protein
KOILJNNC_01710 8.4e-117 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
KOILJNNC_01711 3e-139 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
KOILJNNC_01712 1.8e-245 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KOILJNNC_01713 4.9e-153 ywqG S Domain of unknown function (DUF1963)
KOILJNNC_01714 3.1e-21 S Domain of unknown function (DUF5082)
KOILJNNC_01715 3.9e-38 ywqI S Family of unknown function (DUF5344)
KOILJNNC_01716 3.9e-214 ywqJ S Pre-toxin TG
KOILJNNC_01717 4.7e-43
KOILJNNC_01718 5.2e-17
KOILJNNC_01719 1.4e-80 ywqJ S Pre-toxin TG
KOILJNNC_01720 3.9e-25
KOILJNNC_01721 1.3e-117 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
KOILJNNC_01722 1.6e-160 K Transcriptional regulator
KOILJNNC_01723 1.4e-98 ywqN S NAD(P)H-dependent
KOILJNNC_01725 7.6e-89 ywrA P COG2059 Chromate transport protein ChrA
KOILJNNC_01726 9.2e-104 ywrB P Chromate transporter
KOILJNNC_01727 8e-82 ywrC K Transcriptional regulator
KOILJNNC_01728 2.8e-309 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
KOILJNNC_01729 5e-54 S Domain of unknown function (DUF4181)
KOILJNNC_01730 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KOILJNNC_01732 6.2e-207 cotH M Spore Coat
KOILJNNC_01733 3.9e-125 cotB
KOILJNNC_01734 4.1e-124 ywrJ
KOILJNNC_01735 3e-218 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KOILJNNC_01736 1.1e-169 alsR K LysR substrate binding domain
KOILJNNC_01737 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
KOILJNNC_01738 6.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
KOILJNNC_01739 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
KOILJNNC_01740 8e-48 ywsA S Protein of unknown function (DUF3892)
KOILJNNC_01741 7.3e-92 batE T Sh3 type 3 domain protein
KOILJNNC_01742 2.8e-160 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
KOILJNNC_01743 5.5e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
KOILJNNC_01744 3.3e-275 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
KOILJNNC_01745 4e-63 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
KOILJNNC_01746 8.4e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KOILJNNC_01747 2.1e-177 rbsR K transcriptional
KOILJNNC_01748 1e-223 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
KOILJNNC_01749 8.6e-70 pgsC S biosynthesis protein
KOILJNNC_01750 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
KOILJNNC_01751 3.6e-21 ywtC
KOILJNNC_01752 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KOILJNNC_01753 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
KOILJNNC_01754 2.4e-170 ywtF K Transcriptional regulator
KOILJNNC_01755 7.8e-247 ywtG EGP Major facilitator Superfamily
KOILJNNC_01756 2.2e-207 gerAC S Spore germination protein
KOILJNNC_01757 9.5e-195 gerBB E Spore germination protein
KOILJNNC_01758 5.7e-264 gerBA EG Spore germination protein
KOILJNNC_01759 4.6e-190 pmi 5.3.1.8 G mannose-6-phosphate isomerase
KOILJNNC_01760 6.8e-215 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KOILJNNC_01761 2.5e-192 tarL 2.7.8.14, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOILJNNC_01762 2.5e-89 2.7.8.46 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOILJNNC_01763 6.2e-148 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
KOILJNNC_01764 2.6e-105 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
KOILJNNC_01765 6e-95 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KOILJNNC_01766 7.1e-88 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
KOILJNNC_01767 9.5e-57 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
KOILJNNC_01768 5.3e-135 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KOILJNNC_01769 1.3e-111 ggaA M Glycosyltransferase like family 2
KOILJNNC_01770 1.7e-88
KOILJNNC_01771 2e-131 M Glycosyltransferase like family 2
KOILJNNC_01772 2.5e-148 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
KOILJNNC_01773 5e-132 tagG GM Transport permease protein
KOILJNNC_01774 1.1e-268 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
KOILJNNC_01775 2e-163 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
KOILJNNC_01776 2.4e-22 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KOILJNNC_01777 5.4e-100 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
KOILJNNC_01778 2.1e-88 M Glycosyltransferase like family 2
KOILJNNC_01779 2.1e-213 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
KOILJNNC_01780 2.7e-158 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
KOILJNNC_01781 1e-11
KOILJNNC_01782 0.0 lytB 3.5.1.28 D Stage II sporulation protein
KOILJNNC_01783 1e-207 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KOILJNNC_01784 1.5e-94 M Glycosyltransferase like family 2
KOILJNNC_01785 4.6e-112 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KOILJNNC_01786 4.8e-247 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_01787 2.5e-217 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
KOILJNNC_01788 5.5e-256 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KOILJNNC_01789 6.3e-263 tuaE M Teichuronic acid biosynthesis protein
KOILJNNC_01790 1.5e-113 tuaF M protein involved in exopolysaccharide biosynthesis
KOILJNNC_01791 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
KOILJNNC_01792 8.6e-234 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
KOILJNNC_01793 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
KOILJNNC_01794 6e-163 yvhJ K Transcriptional regulator
KOILJNNC_01795 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
KOILJNNC_01796 1.5e-182 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
KOILJNNC_01797 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_01798 2.1e-154 degV S protein conserved in bacteria
KOILJNNC_01799 7.6e-266 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
KOILJNNC_01800 3.7e-45 comFB S Late competence development protein ComFB
KOILJNNC_01801 2.6e-80 comFC S Phosphoribosyl transferase domain
KOILJNNC_01802 7e-74 yvyF S flagellar protein
KOILJNNC_01803 8e-39 flgM KNU Negative regulator of flagellin synthesis
KOILJNNC_01804 4.1e-78 flgN NOU FlgN protein
KOILJNNC_01805 1.2e-264 flgK N flagellar hook-associated protein
KOILJNNC_01806 7.8e-155 flgL N Belongs to the bacterial flagellin family
KOILJNNC_01807 1.3e-49 yviE
KOILJNNC_01808 1.2e-71 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
KOILJNNC_01809 3.7e-29 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KOILJNNC_01810 4.4e-96 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KOILJNNC_01811 1.2e-55 flaG N flagellar protein FlaG
KOILJNNC_01812 2e-256 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
KOILJNNC_01813 6.5e-69 fliS N flagellar protein FliS
KOILJNNC_01814 1.9e-08 fliT S bacterial-type flagellum organization
KOILJNNC_01815 3e-50
KOILJNNC_01816 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KOILJNNC_01817 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
KOILJNNC_01818 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KOILJNNC_01819 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
KOILJNNC_01820 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
KOILJNNC_01821 1.6e-123 ftsE D cell division ATP-binding protein FtsE
KOILJNNC_01822 2.1e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
KOILJNNC_01823 2.6e-269 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
KOILJNNC_01824 5.3e-56 swrA S Swarming motility protein
KOILJNNC_01825 3.2e-220 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KOILJNNC_01826 3.3e-226 yvkA EGP Major facilitator Superfamily
KOILJNNC_01827 1e-99 yvkB K Transcriptional regulator
KOILJNNC_01828 0.0 yvkC 2.7.9.2 GT Phosphotransferase
KOILJNNC_01829 1.2e-30 csbA S protein conserved in bacteria
KOILJNNC_01830 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
KOILJNNC_01831 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
KOILJNNC_01832 1.2e-114 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
KOILJNNC_01833 5.7e-33 yvkN
KOILJNNC_01834 8e-49 yvlA
KOILJNNC_01835 9.2e-166 yvlB S Putative adhesin
KOILJNNC_01836 2.6e-26 pspB KT PspC domain
KOILJNNC_01837 1.2e-50 yvlD S Membrane
KOILJNNC_01838 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
KOILJNNC_01839 1.2e-132 yvoA K transcriptional
KOILJNNC_01840 8.3e-131 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOILJNNC_01841 1.1e-220 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
KOILJNNC_01842 4.9e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KOILJNNC_01843 1.4e-147 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KOILJNNC_01844 5.8e-161 yvoD P COG0370 Fe2 transport system protein B
KOILJNNC_01845 9.4e-118 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
KOILJNNC_01846 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
KOILJNNC_01847 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
KOILJNNC_01848 4.5e-140 yvpB NU protein conserved in bacteria
KOILJNNC_01849 2.4e-220 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KOILJNNC_01850 7.4e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
KOILJNNC_01851 8.4e-227 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KOILJNNC_01852 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
KOILJNNC_01853 7.6e-112 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KOILJNNC_01854 5.5e-130 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KOILJNNC_01855 1.4e-136 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
KOILJNNC_01856 4.1e-110 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
KOILJNNC_01857 1.3e-64
KOILJNNC_01858 0.0
KOILJNNC_01860 0.0 msbA2 3.6.3.44 V ABC transporter
KOILJNNC_01861 2.1e-274 S COG0457 FOG TPR repeat
KOILJNNC_01862 5.6e-99 usp CBM50 M protein conserved in bacteria
KOILJNNC_01863 2.5e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
KOILJNNC_01864 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
KOILJNNC_01865 5.7e-166 rapZ S Displays ATPase and GTPase activities
KOILJNNC_01866 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
KOILJNNC_01867 1.4e-170 whiA K May be required for sporulation
KOILJNNC_01868 1.6e-36 crh G Phosphocarrier protein Chr
KOILJNNC_01869 4.3e-146 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
KOILJNNC_01870 5.7e-32
KOILJNNC_01871 9.6e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_01872 2e-197 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
KOILJNNC_01873 5.6e-141 yvcR V ABC transporter, ATP-binding protein
KOILJNNC_01874 0.0 yxdM V ABC transporter (permease)
KOILJNNC_01875 5.1e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KOILJNNC_01876 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
KOILJNNC_01877 1.1e-287 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
KOILJNNC_01878 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
KOILJNNC_01879 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
KOILJNNC_01880 3.9e-173 yvdE K Transcriptional regulator
KOILJNNC_01881 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
KOILJNNC_01882 4e-234 mdxE G COG2182 Maltose-binding periplasmic proteins domains
KOILJNNC_01883 1e-243 malC P COG1175 ABC-type sugar transport systems, permease components
KOILJNNC_01884 3.9e-148 malD P transport
KOILJNNC_01885 3.2e-153 malA S Protein of unknown function (DUF1189)
KOILJNNC_01886 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
KOILJNNC_01887 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
KOILJNNC_01888 2e-115 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
KOILJNNC_01889 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
KOILJNNC_01891 2.3e-173 S Patatin-like phospholipase
KOILJNNC_01893 4.8e-93 yvdQ S Protein of unknown function (DUF3231)
KOILJNNC_01894 7.1e-50 sugE P Small Multidrug Resistance protein
KOILJNNC_01895 6.7e-51 ykkC P Small Multidrug Resistance protein
KOILJNNC_01896 8.2e-105 yvdT K Transcriptional regulator
KOILJNNC_01897 3.9e-295 yveA E amino acid
KOILJNNC_01898 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
KOILJNNC_01899 5e-273 sacB 2.4.1.10 GH68 M levansucrase activity
KOILJNNC_01900 6.7e-259 pbpE V Beta-lactamase
KOILJNNC_01901 1.4e-124 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
KOILJNNC_01902 8.4e-73 MA20_18690 S Protein of unknown function (DUF3237)
KOILJNNC_01903 5.1e-92 padC Q Phenolic acid decarboxylase
KOILJNNC_01904 2.7e-277 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
KOILJNNC_01905 6.3e-76 slr K transcriptional
KOILJNNC_01906 4e-122 ywqC M biosynthesis protein
KOILJNNC_01907 3e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
KOILJNNC_01908 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
KOILJNNC_01909 2.2e-218 epsD GT4 M Glycosyl transferase 4-like
KOILJNNC_01910 4.5e-157 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_01911 1.4e-217 epsF GT4 M Glycosyl transferases group 1
KOILJNNC_01912 1.1e-206 epsG S EpsG family
KOILJNNC_01913 4.4e-194 epsH GT2 S Glycosyltransferase like family 2
KOILJNNC_01914 2e-205 epsI GM pyruvyl transferase
KOILJNNC_01915 3.5e-191 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_01916 1.3e-258 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_01917 2.4e-107 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
KOILJNNC_01918 2.4e-52 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
KOILJNNC_01919 4.5e-219 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
KOILJNNC_01920 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
KOILJNNC_01921 1e-31 yvfG S YvfG protein
KOILJNNC_01922 9.4e-242 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
KOILJNNC_01923 1.4e-306 yvfH C L-lactate permease
KOILJNNC_01924 1e-112 yvfI K COG2186 Transcriptional regulators
KOILJNNC_01925 3e-184 lacR K Transcriptional regulator
KOILJNNC_01926 4.4e-228 cycB G COG2182 Maltose-binding periplasmic proteins domains
KOILJNNC_01927 2.9e-232 malC P COG1175 ABC-type sugar transport systems, permease components
KOILJNNC_01928 7.2e-150 ganQ P transport
KOILJNNC_01929 0.0 lacA 3.2.1.23 G beta-galactosidase
KOILJNNC_01930 2.2e-251 galA 3.2.1.89 G arabinogalactan
KOILJNNC_01931 2.9e-197 rsbU 3.1.3.3 T response regulator
KOILJNNC_01932 5.4e-135 rsbQ S Alpha/beta hydrolase family
KOILJNNC_01933 1.1e-10 rsbQ S Alpha/beta hydrolase family
KOILJNNC_01934 3.1e-159 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
KOILJNNC_01935 9.9e-132 yvfS V COG0842 ABC-type multidrug transport system, permease component
KOILJNNC_01936 4.6e-197 desK 2.7.13.3 T Histidine kinase
KOILJNNC_01937 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_01938 2.2e-136 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KOILJNNC_01939 2.7e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
KOILJNNC_01940 6.7e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
KOILJNNC_01941 6.8e-195 yvbX S Glycosyl hydrolase
KOILJNNC_01942 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_01943 9.4e-156 yvbV EG EamA-like transporter family
KOILJNNC_01944 3.9e-159 yvbU K Transcriptional regulator
KOILJNNC_01945 5.8e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_01946 2.1e-202 araR K transcriptional
KOILJNNC_01947 1.6e-252 araE EGP Major facilitator Superfamily
KOILJNNC_01948 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
KOILJNNC_01949 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
KOILJNNC_01950 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
KOILJNNC_01951 4.8e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
KOILJNNC_01952 2.2e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
KOILJNNC_01953 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
KOILJNNC_01954 8.3e-76 yvbK 3.1.3.25 K acetyltransferase
KOILJNNC_01955 0.0 tcaA S response to antibiotic
KOILJNNC_01956 4e-122 exoY M Membrane
KOILJNNC_01957 8.6e-113 yvbH S YvbH-like oligomerisation region
KOILJNNC_01958 2.3e-100 yvbG U UPF0056 membrane protein
KOILJNNC_01959 3.5e-97 yvbF K Belongs to the GbsR family
KOILJNNC_01960 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KOILJNNC_01961 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KOILJNNC_01962 1.8e-170 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KOILJNNC_01963 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KOILJNNC_01964 4.5e-45 sdpR K transcriptional
KOILJNNC_01965 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
KOILJNNC_01966 4.4e-08
KOILJNNC_01967 7.6e-172
KOILJNNC_01968 7.9e-13 S Sporulation delaying protein SdpA
KOILJNNC_01969 2.5e-60 yvbF K Belongs to the GbsR family
KOILJNNC_01970 2.4e-209 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
KOILJNNC_01971 5.6e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
KOILJNNC_01972 2.7e-171 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
KOILJNNC_01973 2.4e-111 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
KOILJNNC_01974 1.9e-218 NT chemotaxis protein
KOILJNNC_01975 2.2e-54 yodB K transcriptional
KOILJNNC_01976 5.2e-69 yvaO K Cro/C1-type HTH DNA-binding domain
KOILJNNC_01977 4e-69 K transcriptional
KOILJNNC_01978 7.5e-36 yvzC K Transcriptional
KOILJNNC_01979 9.1e-152 yvaM S Serine aminopeptidase, S33
KOILJNNC_01980 2.4e-23 secG U Preprotein translocase subunit SecG
KOILJNNC_01981 5.6e-143 est 3.1.1.1 S Carboxylesterase
KOILJNNC_01982 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
KOILJNNC_01983 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KOILJNNC_01985 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_01986 1.5e-98 K Bacterial regulatory proteins, tetR family
KOILJNNC_01987 5.3e-54 yvaE P Small Multidrug Resistance protein
KOILJNNC_01988 1.3e-72 yvaD S Family of unknown function (DUF5360)
KOILJNNC_01989 0.0 yvaC S Fusaric acid resistance protein-like
KOILJNNC_01990 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KOILJNNC_01991 8.4e-193 yvaA 1.1.1.371 S Oxidoreductase
KOILJNNC_01992 2.2e-48 csoR S transcriptional
KOILJNNC_01993 1.5e-29 copZ P Copper resistance protein CopZ
KOILJNNC_01994 0.0 copA 3.6.3.54 P P-type ATPase
KOILJNNC_01995 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KOILJNNC_01996 1.4e-103 bdbD O Thioredoxin
KOILJNNC_01997 1.9e-71 bdbC O Required for disulfide bond formation in some proteins
KOILJNNC_01998 1.6e-106 yvgT S membrane
KOILJNNC_02000 0.0 helD 3.6.4.12 L DNA helicase
KOILJNNC_02001 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KOILJNNC_02002 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
KOILJNNC_02003 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
KOILJNNC_02004 2.1e-85 yvgO
KOILJNNC_02005 5.9e-157 yvgN S reductase
KOILJNNC_02006 9e-119 modB P COG4149 ABC-type molybdate transport system, permease component
KOILJNNC_02007 4.1e-136 modA P COG0725 ABC-type molybdate transport system, periplasmic component
KOILJNNC_02008 7.5e-169 yvgK P COG1910 Periplasmic molybdate-binding protein domain
KOILJNNC_02009 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOILJNNC_02010 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
KOILJNNC_02011 6.5e-16 S Small spore protein J (Spore_SspJ)
KOILJNNC_02012 4.9e-236 yvsH E Arginine ornithine antiporter
KOILJNNC_02013 2.6e-177 fhuD P ABC transporter
KOILJNNC_02014 7.9e-183 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_02015 3.4e-175 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_02016 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
KOILJNNC_02017 2e-174 M Efflux transporter rnd family, mfp subunit
KOILJNNC_02018 1.6e-123 macB V ABC transporter, ATP-binding protein
KOILJNNC_02019 4e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
KOILJNNC_02020 3.8e-64 yvrL S Regulatory protein YrvL
KOILJNNC_02021 8.1e-229 oxdC 4.1.1.2 G Oxalate decarboxylase
KOILJNNC_02022 2.4e-19 S YvrJ protein family
KOILJNNC_02023 9.5e-98 yvrI K RNA polymerase
KOILJNNC_02024 3.6e-22
KOILJNNC_02025 2.8e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_02026 0.0 T PhoQ Sensor
KOILJNNC_02027 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
KOILJNNC_02028 1.4e-139 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_02029 8.4e-168 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
KOILJNNC_02030 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_02031 3e-243 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
KOILJNNC_02032 6.1e-100 yvqK 2.5.1.17 S Adenosyltransferase
KOILJNNC_02033 4.8e-227 yvqJ EGP Major facilitator Superfamily
KOILJNNC_02034 8.1e-61 liaI S membrane
KOILJNNC_02035 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
KOILJNNC_02036 1.8e-119 liaG S Putative adhesin
KOILJNNC_02037 3.6e-126 yvqF S Cell wall-active antibiotics response 4TMS YvqF
KOILJNNC_02038 7.9e-186 vraS 2.7.13.3 T Histidine kinase
KOILJNNC_02039 1.9e-107 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_02040 4.1e-185 gerAC S Spore germination B3/ GerAC like, C-terminal
KOILJNNC_02041 1.5e-195 gerAB E Spore germination protein
KOILJNNC_02042 3.1e-246 gerAA EG Spore germination protein
KOILJNNC_02043 2.3e-24 S Protein of unknown function (DUF3970)
KOILJNNC_02044 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
KOILJNNC_02045 3.6e-157 yuxN K Transcriptional regulator
KOILJNNC_02046 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
KOILJNNC_02047 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_02048 3.1e-235 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KOILJNNC_02049 1.2e-79 dps P Ferritin-like domain
KOILJNNC_02050 4.4e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_02051 1.4e-299 pepF2 E COG1164 Oligoendopeptidase F
KOILJNNC_02052 1.1e-66 S YusW-like protein
KOILJNNC_02053 1e-153 yusV 3.6.3.34 HP ABC transporter
KOILJNNC_02054 7.3e-39 yusU S Protein of unknown function (DUF2573)
KOILJNNC_02055 5.7e-158 yusT K LysR substrate binding domain
KOILJNNC_02056 5e-107 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_02057 8.4e-66 yusQ S Tautomerase enzyme
KOILJNNC_02058 8.5e-293 yusP P Major facilitator superfamily
KOILJNNC_02059 5.3e-67 yusO K Iron dependent repressor, N-terminal DNA binding domain
KOILJNNC_02060 5.4e-53 yusN M Coat F domain
KOILJNNC_02061 5.1e-40
KOILJNNC_02062 8.4e-165 fadM E Proline dehydrogenase
KOILJNNC_02063 8.1e-09 S YuzL-like protein
KOILJNNC_02064 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
KOILJNNC_02065 7.9e-216 fadA 2.3.1.16 I Belongs to the thiolase family
KOILJNNC_02066 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
KOILJNNC_02067 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
KOILJNNC_02068 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
KOILJNNC_02069 1.1e-39 yusG S Protein of unknown function (DUF2553)
KOILJNNC_02070 1.3e-73 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
KOILJNNC_02071 5.6e-55 traF CO Thioredoxin
KOILJNNC_02072 2.4e-56 yusD S SCP-2 sterol transfer family
KOILJNNC_02073 8.3e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KOILJNNC_02074 2.3e-95 metI P COG2011 ABC-type metal ion transport system, permease component
KOILJNNC_02075 7.2e-147 metQ P Belongs to the NlpA lipoprotein family
KOILJNNC_02076 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
KOILJNNC_02077 1.4e-245 sufD O assembly protein SufD
KOILJNNC_02078 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KOILJNNC_02079 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
KOILJNNC_02080 3.5e-271 sufB O FeS cluster assembly
KOILJNNC_02081 1.3e-63 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_02082 1e-41
KOILJNNC_02084 8.4e-207 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
KOILJNNC_02085 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
KOILJNNC_02086 8.2e-182 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
KOILJNNC_02087 3.2e-239 yurO G COG1653 ABC-type sugar transport system, periplasmic component
KOILJNNC_02088 1.5e-155 yurN G Binding-protein-dependent transport system inner membrane component
KOILJNNC_02089 8.1e-168 yurM P COG0395 ABC-type sugar transport system, permease component
KOILJNNC_02090 1.4e-161 yurL 2.7.1.218 G pfkB family carbohydrate kinase
KOILJNNC_02091 2.5e-135 yurK K UTRA
KOILJNNC_02092 1.2e-205 msmX P Belongs to the ABC transporter superfamily
KOILJNNC_02093 1.2e-168 bsn L Ribonuclease
KOILJNNC_02094 1.2e-230 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
KOILJNNC_02095 7.3e-236 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
KOILJNNC_02096 2.2e-182 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
KOILJNNC_02097 1.7e-108 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
KOILJNNC_02098 7.3e-147 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
KOILJNNC_02099 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
KOILJNNC_02100 1.8e-95 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
KOILJNNC_02103 1e-54 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
KOILJNNC_02104 1.9e-278 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
KOILJNNC_02105 9.6e-223 pbuX F xanthine
KOILJNNC_02106 1.7e-230 pbuX F Permease family
KOILJNNC_02107 1.6e-299 pucR QT COG2508 Regulator of polyketide synthase expression
KOILJNNC_02108 1.1e-256 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
KOILJNNC_02109 3.1e-59 yunG
KOILJNNC_02110 4.3e-171 yunF S Protein of unknown function DUF72
KOILJNNC_02111 1e-140 yunE S membrane transporter protein
KOILJNNC_02112 2.4e-264 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
KOILJNNC_02113 3.1e-47 yunC S Domain of unknown function (DUF1805)
KOILJNNC_02114 3.2e-133 yunB S Sporulation protein YunB (Spo_YunB)
KOILJNNC_02115 1.1e-194 lytH M Peptidase, M23
KOILJNNC_02116 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KOILJNNC_02117 8.3e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KOILJNNC_02118 9.7e-48 yutD S protein conserved in bacteria
KOILJNNC_02119 1.9e-74 yutE S Protein of unknown function DUF86
KOILJNNC_02120 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
KOILJNNC_02121 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
KOILJNNC_02122 5e-198 yutH S Spore coat protein
KOILJNNC_02123 4.6e-241 hom 1.1.1.3 E homoserine dehydrogenase
KOILJNNC_02124 6.8e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KOILJNNC_02125 2.5e-172 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
KOILJNNC_02126 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
KOILJNNC_02127 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
KOILJNNC_02128 9.6e-55 yuzD S protein conserved in bacteria
KOILJNNC_02129 2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
KOILJNNC_02130 3.2e-39 yuzB S Belongs to the UPF0349 family
KOILJNNC_02131 5.3e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KOILJNNC_02132 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KOILJNNC_02133 3.7e-63 erpA S Belongs to the HesB IscA family
KOILJNNC_02134 6.1e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_02135 8.5e-116 paiB K Putative FMN-binding domain
KOILJNNC_02136 2.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
KOILJNNC_02138 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
KOILJNNC_02139 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
KOILJNNC_02140 8.4e-27 yuiB S Putative membrane protein
KOILJNNC_02141 2.1e-117 yuiC S protein conserved in bacteria
KOILJNNC_02142 2e-77 yuiD S protein conserved in bacteria
KOILJNNC_02143 2.2e-279 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KOILJNNC_02144 1.1e-210 yuiF S antiporter
KOILJNNC_02145 7.4e-93 bioY S Biotin biosynthesis protein
KOILJNNC_02146 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
KOILJNNC_02147 2.5e-166 besA S Putative esterase
KOILJNNC_02148 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_02149 4.3e-225 entC 5.4.4.2 HQ Isochorismate synthase
KOILJNNC_02150 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
KOILJNNC_02151 4.9e-176 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
KOILJNNC_02152 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_02153 5.5e-35 mbtH S MbtH-like protein
KOILJNNC_02154 9.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
KOILJNNC_02155 6.1e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
KOILJNNC_02156 1.3e-224 yukF QT Transcriptional regulator
KOILJNNC_02157 2.8e-45 esxA S Belongs to the WXG100 family
KOILJNNC_02158 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
KOILJNNC_02159 5.2e-211 essB S WXG100 protein secretion system (Wss), protein YukC
KOILJNNC_02160 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
KOILJNNC_02161 0.0 esaA S type VII secretion protein EsaA
KOILJNNC_02162 3.3e-64 yueC S Family of unknown function (DUF5383)
KOILJNNC_02163 6.4e-131 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_02164 4.8e-96 yueE S phosphohydrolase
KOILJNNC_02165 6.4e-24 S Protein of unknown function (DUF2642)
KOILJNNC_02166 2.2e-69 S Protein of unknown function (DUF2283)
KOILJNNC_02167 3.2e-190 yueF S transporter activity
KOILJNNC_02168 6.6e-31 yueG S Spore germination protein gerPA/gerPF
KOILJNNC_02169 2.8e-38 yueH S YueH-like protein
KOILJNNC_02170 7.9e-67 yueI S Protein of unknown function (DUF1694)
KOILJNNC_02171 7.3e-103 pncA Q COG1335 Amidases related to nicotinamidase
KOILJNNC_02172 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KOILJNNC_02173 1.1e-231 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
KOILJNNC_02174 8.5e-23 yuzC
KOILJNNC_02176 3.6e-142 comQ H Belongs to the FPP GGPP synthase family
KOILJNNC_02178 3.2e-269 comP 2.7.13.3 T Histidine kinase
KOILJNNC_02179 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_02180 2.3e-63 ydiI Q protein, possibly involved in aromatic compounds catabolism
KOILJNNC_02181 5.7e-59 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
KOILJNNC_02182 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KOILJNNC_02183 1.1e-78 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KOILJNNC_02184 3.5e-261 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KOILJNNC_02185 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KOILJNNC_02186 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
KOILJNNC_02187 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KOILJNNC_02188 5e-15
KOILJNNC_02189 8.2e-233 maeN C COG3493 Na citrate symporter
KOILJNNC_02190 2.9e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
KOILJNNC_02191 2.5e-184 yufP S Belongs to the binding-protein-dependent transport system permease family
KOILJNNC_02192 2.1e-269 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
KOILJNNC_02193 2.2e-196 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
KOILJNNC_02194 3.9e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
KOILJNNC_02195 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KOILJNNC_02196 6.3e-78 yufK S Family of unknown function (DUF5366)
KOILJNNC_02197 6.3e-75 yuxK S protein conserved in bacteria
KOILJNNC_02198 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
KOILJNNC_02199 4.7e-183 yuxJ EGP Major facilitator Superfamily
KOILJNNC_02201 1.9e-115 kapD L the KinA pathway to sporulation
KOILJNNC_02202 7.4e-70 kapB G Kinase associated protein B
KOILJNNC_02203 4.6e-233 T PhoQ Sensor
KOILJNNC_02204 5.8e-227 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
KOILJNNC_02205 4.6e-39 yugE S Domain of unknown function (DUF1871)
KOILJNNC_02206 9.3e-155 yugF I Hydrolase
KOILJNNC_02207 1.6e-85 alaR K Transcriptional regulator
KOILJNNC_02208 1.4e-198 yugH 2.6.1.1 E Aminotransferase
KOILJNNC_02209 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
KOILJNNC_02210 1.1e-34 yuzA S Domain of unknown function (DUF378)
KOILJNNC_02211 5.8e-227 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
KOILJNNC_02212 3.4e-227 yugK C Dehydrogenase
KOILJNNC_02213 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
KOILJNNC_02215 1.3e-72 yugN S YugN-like family
KOILJNNC_02216 1.1e-181 yugO P COG1226 Kef-type K transport systems
KOILJNNC_02217 1.1e-53 mstX S Membrane-integrating protein Mistic
KOILJNNC_02218 2.3e-38
KOILJNNC_02219 1.4e-116 yugP S Zn-dependent protease
KOILJNNC_02220 2.9e-235 yugS S COG1253 Hemolysins and related proteins containing CBS domains
KOILJNNC_02221 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
KOILJNNC_02222 9e-71 yugU S Uncharacterised protein family UPF0047
KOILJNNC_02223 1e-35
KOILJNNC_02224 9.9e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
KOILJNNC_02225 1.6e-224 mcpA NT chemotaxis protein
KOILJNNC_02226 6.9e-220 mcpA NT chemotaxis protein
KOILJNNC_02227 5.5e-294 mcpA NT chemotaxis protein
KOILJNNC_02228 1.6e-237 mcpA NT chemotaxis protein
KOILJNNC_02229 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
KOILJNNC_02230 3.8e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
KOILJNNC_02231 6.7e-273 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
KOILJNNC_02232 1.6e-54 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
KOILJNNC_02233 1.4e-250 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
KOILJNNC_02234 9.7e-183 ygjR S Oxidoreductase
KOILJNNC_02235 3.7e-189 yubA S transporter activity
KOILJNNC_02236 2.7e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
KOILJNNC_02238 1.3e-87 cdoA 1.13.11.20 S Cysteine dioxygenase type I
KOILJNNC_02239 4.9e-274 yubD P Major Facilitator Superfamily
KOILJNNC_02240 5.4e-152 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
KOILJNNC_02241 1e-38 yiaA S yiaA/B two helix domain
KOILJNNC_02242 1.6e-236 ktrB P Potassium
KOILJNNC_02243 1.9e-121 ktrA P COG0569 K transport systems, NAD-binding component
KOILJNNC_02244 2.2e-91 yuaB
KOILJNNC_02245 5.5e-95 yuaC K Belongs to the GbsR family
KOILJNNC_02246 8.8e-281 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
KOILJNNC_02247 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
KOILJNNC_02248 3.9e-107 yuaD
KOILJNNC_02249 3.9e-84 yuaE S DinB superfamily
KOILJNNC_02250 1e-74 yuaF OU Membrane protein implicated in regulation of membrane protease activity
KOILJNNC_02251 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
KOILJNNC_02252 9.9e-94 M1-753 M FR47-like protein
KOILJNNC_02253 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
KOILJNNC_02258 7.8e-08
KOILJNNC_02266 2e-08
KOILJNNC_02270 5.9e-143 spo0M S COG4326 Sporulation control protein
KOILJNNC_02271 4.4e-26
KOILJNNC_02272 5.1e-130 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
KOILJNNC_02273 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KOILJNNC_02274 1.2e-260 ygaK C Berberine and berberine like
KOILJNNC_02276 7.9e-290 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
KOILJNNC_02277 3e-139 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
KOILJNNC_02278 4e-168 ssuA M Sulfonate ABC transporter
KOILJNNC_02279 3.2e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
KOILJNNC_02280 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
KOILJNNC_02282 5e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOILJNNC_02283 4.2e-75 ygaO
KOILJNNC_02284 4.4e-29 K Transcriptional regulator
KOILJNNC_02286 8.7e-113 yhzB S B3/4 domain
KOILJNNC_02287 6e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KOILJNNC_02288 4.8e-176 yhbB S Putative amidase domain
KOILJNNC_02289 9e-86 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
KOILJNNC_02290 1.3e-108 yhbD K Protein of unknown function (DUF4004)
KOILJNNC_02291 1.4e-58 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
KOILJNNC_02292 2.3e-69 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
KOILJNNC_02293 0.0 prkA T Ser protein kinase
KOILJNNC_02294 2.5e-225 yhbH S Belongs to the UPF0229 family
KOILJNNC_02295 2.2e-76 yhbI K DNA-binding transcription factor activity
KOILJNNC_02296 4e-97 yhbJ V COG1566 Multidrug resistance efflux pump
KOILJNNC_02297 3.1e-271 yhcA EGP Major facilitator Superfamily
KOILJNNC_02298 1.4e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
KOILJNNC_02299 2.8e-37 yhcC
KOILJNNC_02300 5e-54
KOILJNNC_02301 1.9e-59 yhcF K Transcriptional regulator
KOILJNNC_02302 1.5e-121 yhcG V ABC transporter, ATP-binding protein
KOILJNNC_02303 7.7e-166 yhcH V ABC transporter, ATP-binding protein
KOILJNNC_02304 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KOILJNNC_02305 1e-30 cspB K Cold-shock protein
KOILJNNC_02306 8.3e-151 metQ M Belongs to the nlpA lipoprotein family
KOILJNNC_02307 2.9e-196 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
KOILJNNC_02308 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOILJNNC_02309 1.1e-40 yhcM
KOILJNNC_02310 6e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KOILJNNC_02311 4.8e-166 yhcP
KOILJNNC_02312 5.8e-99 yhcQ M Spore coat protein
KOILJNNC_02313 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
KOILJNNC_02314 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
KOILJNNC_02315 2.8e-168 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOILJNNC_02316 9.3e-68 yhcU S Family of unknown function (DUF5365)
KOILJNNC_02317 9.9e-68 yhcV S COG0517 FOG CBS domain
KOILJNNC_02318 4.6e-120 yhcW 5.4.2.6 S hydrolase
KOILJNNC_02319 7.8e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KOILJNNC_02320 6e-260 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KOILJNNC_02321 2e-103 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
KOILJNNC_02322 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
KOILJNNC_02323 6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KOILJNNC_02324 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KOILJNNC_02325 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
KOILJNNC_02326 4e-212 yhcY 2.7.13.3 T Histidine kinase
KOILJNNC_02327 8.5e-111 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_02328 6.1e-83 azr 1.7.1.6 S NADPH-dependent FMN reductase
KOILJNNC_02329 1.2e-38 yhdB S YhdB-like protein
KOILJNNC_02330 1.8e-53 yhdC S Protein of unknown function (DUF3889)
KOILJNNC_02331 9e-185 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KOILJNNC_02332 1e-75 nsrR K Transcriptional regulator
KOILJNNC_02333 7.3e-238 ygxB M Conserved TM helix
KOILJNNC_02334 2.1e-276 ycgB S Stage V sporulation protein R
KOILJNNC_02335 3.2e-256 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KOILJNNC_02336 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
KOILJNNC_02337 3.8e-162 citR K Transcriptional regulator
KOILJNNC_02338 4.1e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
KOILJNNC_02339 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_02340 3.4e-250 yhdG E amino acid
KOILJNNC_02341 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
KOILJNNC_02342 8.5e-265 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_02343 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_02344 8.1e-45 yhdK S Sigma-M inhibitor protein
KOILJNNC_02345 2.5e-200 yhdL S Sigma factor regulator N-terminal
KOILJNNC_02346 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_02347 4.4e-191 yhdN C Aldo keto reductase
KOILJNNC_02348 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
KOILJNNC_02349 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
KOILJNNC_02350 4.1e-74 cueR K transcriptional
KOILJNNC_02351 9.7e-222 yhdR 2.6.1.1 E Aminotransferase
KOILJNNC_02352 3.9e-246 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
KOILJNNC_02353 5.5e-43 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOILJNNC_02354 4.3e-65 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KOILJNNC_02355 1.8e-133 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KOILJNNC_02357 9.9e-184 yhdY M Mechanosensitive ion channel
KOILJNNC_02358 9.4e-138 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
KOILJNNC_02359 8.2e-146 yheN G deacetylase
KOILJNNC_02360 4e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
KOILJNNC_02361 1.3e-230 nhaC C Na H antiporter
KOILJNNC_02362 3.4e-84 nhaX T Belongs to the universal stress protein A family
KOILJNNC_02363 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
KOILJNNC_02364 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
KOILJNNC_02365 3.8e-108 yheG GM NAD(P)H-binding
KOILJNNC_02366 6.3e-28 sspB S spore protein
KOILJNNC_02367 3.8e-36 yheE S Family of unknown function (DUF5342)
KOILJNNC_02368 1.5e-266 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
KOILJNNC_02369 4.3e-216 yheC HJ YheC/D like ATP-grasp
KOILJNNC_02370 2.2e-202 yheB S Belongs to the UPF0754 family
KOILJNNC_02371 9.5e-48 yheA S Belongs to the UPF0342 family
KOILJNNC_02372 4.9e-204 yhaZ L DNA alkylation repair enzyme
KOILJNNC_02373 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
KOILJNNC_02374 5.1e-292 hemZ H coproporphyrinogen III oxidase
KOILJNNC_02375 4.1e-207 yhaU P COG0475 Kef-type K transport systems, membrane components
KOILJNNC_02376 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
KOILJNNC_02378 1.2e-130 yhaR 5.3.3.18 I enoyl-CoA hydratase
KOILJNNC_02379 2.4e-26 S YhzD-like protein
KOILJNNC_02380 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
KOILJNNC_02381 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
KOILJNNC_02382 6.3e-224 yhaO L DNA repair exonuclease
KOILJNNC_02383 0.0 yhaN L AAA domain
KOILJNNC_02384 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
KOILJNNC_02385 1.6e-21 yhaL S Sporulation protein YhaL
KOILJNNC_02386 1e-119 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
KOILJNNC_02387 8.7e-90 yhaK S Putative zincin peptidase
KOILJNNC_02388 1.3e-54 yhaI S Protein of unknown function (DUF1878)
KOILJNNC_02389 1e-113 hpr K Negative regulator of protease production and sporulation
KOILJNNC_02390 8.2e-39 yhaH S YtxH-like protein
KOILJNNC_02391 3.6e-80 trpP S Tryptophan transporter TrpP
KOILJNNC_02392 2.4e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KOILJNNC_02393 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
KOILJNNC_02394 4.6e-137 ecsA V transporter (ATP-binding protein)
KOILJNNC_02395 3.5e-214 ecsB U ABC transporter
KOILJNNC_02396 6.9e-114 ecsC S EcsC protein family
KOILJNNC_02397 1.8e-228 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
KOILJNNC_02398 1.8e-243 yhfA C membrane
KOILJNNC_02399 1.7e-32 1.15.1.2 C Rubrerythrin
KOILJNNC_02400 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
KOILJNNC_02401 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
KOILJNNC_02402 5.9e-202 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KOILJNNC_02403 4.4e-177 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
KOILJNNC_02404 7.7e-266 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KOILJNNC_02405 5.4e-101 yhgD K Transcriptional regulator
KOILJNNC_02406 1.3e-214 yhgE S YhgE Pip N-terminal domain protein
KOILJNNC_02407 1.1e-183 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOILJNNC_02408 1.1e-136 yhfC S Putative membrane peptidase family (DUF2324)
KOILJNNC_02409 2.3e-198 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
KOILJNNC_02410 3.7e-72 3.4.13.21 S ASCH
KOILJNNC_02411 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOILJNNC_02412 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
KOILJNNC_02413 1.7e-190 lplJ 6.3.1.20 H Lipoate-protein ligase
KOILJNNC_02414 2.2e-111 yhfK GM NmrA-like family
KOILJNNC_02415 1.6e-299 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KOILJNNC_02416 1.4e-63 yhfM
KOILJNNC_02417 1e-240 yhfN 3.4.24.84 O Peptidase M48
KOILJNNC_02418 1.2e-197 aprE 3.4.21.62 O Belongs to the peptidase S8 family
KOILJNNC_02419 1.9e-77 VY92_01935 K acetyltransferase
KOILJNNC_02420 5.4e-181 yhfP 1.1.1.1 C Quinone oxidoreductase
KOILJNNC_02421 1.6e-158 yfmC M Periplasmic binding protein
KOILJNNC_02422 2.1e-108 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
KOILJNNC_02423 5e-196 vraB 2.3.1.9 I Belongs to the thiolase family
KOILJNNC_02424 2.9e-268 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
KOILJNNC_02425 7.9e-89 bioY S BioY family
KOILJNNC_02426 7.8e-180 hemAT NT chemotaxis protein
KOILJNNC_02427 6.1e-301 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
KOILJNNC_02428 1e-156 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_02429 1.3e-32 yhzC S IDEAL
KOILJNNC_02430 1.2e-108 comK K Competence transcription factor
KOILJNNC_02431 8e-168 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_02432 8.1e-39 yhjA S Excalibur calcium-binding domain
KOILJNNC_02433 3.4e-264 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOILJNNC_02434 4.5e-26 yhjC S Protein of unknown function (DUF3311)
KOILJNNC_02435 2.5e-59 yhjD
KOILJNNC_02436 9.1e-110 yhjE S SNARE associated Golgi protein
KOILJNNC_02437 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
KOILJNNC_02438 1.1e-281 yhjG CH FAD binding domain
KOILJNNC_02439 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_02440 1.1e-212 glcP G Major Facilitator Superfamily
KOILJNNC_02441 7.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
KOILJNNC_02442 3.2e-158 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
KOILJNNC_02443 4.1e-253 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
KOILJNNC_02444 4.5e-188 yhjM 5.1.1.1 K Transcriptional regulator
KOILJNNC_02445 4.2e-201 abrB S membrane
KOILJNNC_02446 3.4e-214 EGP Transmembrane secretion effector
KOILJNNC_02447 0.0 S Sugar transport-related sRNA regulator N-term
KOILJNNC_02448 3.8e-78 yhjR S Rubrerythrin
KOILJNNC_02449 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
KOILJNNC_02450 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
KOILJNNC_02451 2e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
KOILJNNC_02452 0.0 sbcC L COG0419 ATPase involved in DNA repair
KOILJNNC_02453 3e-50 yisB V COG1403 Restriction endonuclease
KOILJNNC_02454 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
KOILJNNC_02455 5.3e-63 gerPE S Spore germination protein GerPE
KOILJNNC_02456 1.1e-23 gerPD S Spore germination protein
KOILJNNC_02457 5.3e-54 gerPC S Spore germination protein
KOILJNNC_02458 4e-34 gerPB S cell differentiation
KOILJNNC_02459 1.9e-33 gerPA S Spore germination protein
KOILJNNC_02460 1.5e-22 yisI S Spo0E like sporulation regulatory protein
KOILJNNC_02461 1.5e-172 cotH M Spore Coat
KOILJNNC_02462 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
KOILJNNC_02463 3.9e-57 yisL S UPF0344 protein
KOILJNNC_02464 0.0 wprA O Belongs to the peptidase S8 family
KOILJNNC_02465 6.2e-102 yisN S Protein of unknown function (DUF2777)
KOILJNNC_02466 0.0 asnO 6.3.5.4 E Asparagine synthase
KOILJNNC_02467 4.2e-115 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
KOILJNNC_02468 1.5e-242 yisQ V Mate efflux family protein
KOILJNNC_02469 1.2e-160 yisR K Transcriptional regulator
KOILJNNC_02470 3.8e-182 purR K helix_turn _helix lactose operon repressor
KOILJNNC_02471 2.3e-195 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
KOILJNNC_02472 4.5e-91 yisT S DinB family
KOILJNNC_02473 8e-106 argO S Lysine exporter protein LysE YggA
KOILJNNC_02474 1.1e-272 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_02475 1.5e-35 mcbG S Pentapeptide repeats (9 copies)
KOILJNNC_02476 1.7e-153 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOILJNNC_02477 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
KOILJNNC_02478 8.7e-231 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KOILJNNC_02479 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KOILJNNC_02480 9e-119 comB 3.1.3.71 H Belongs to the ComB family
KOILJNNC_02481 3.5e-140 yitD 4.4.1.19 S synthase
KOILJNNC_02482 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
KOILJNNC_02483 5e-220 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KOILJNNC_02484 1.5e-228 yitG EGP Major facilitator Superfamily
KOILJNNC_02485 4.8e-154 yitH K Acetyltransferase (GNAT) domain
KOILJNNC_02486 4.1e-72 yjcF S Acetyltransferase (GNAT) domain
KOILJNNC_02487 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
KOILJNNC_02488 8.6e-55 yajQ S Belongs to the UPF0234 family
KOILJNNC_02489 3.4e-160 cvfB S protein conserved in bacteria
KOILJNNC_02490 8.5e-94
KOILJNNC_02491 4e-170
KOILJNNC_02492 1.5e-97 S Sporulation delaying protein SdpA
KOILJNNC_02493 1.5e-58 K Transcriptional regulator PadR-like family
KOILJNNC_02494 1.3e-94
KOILJNNC_02495 3.1e-44 yitR S Domain of unknown function (DUF3784)
KOILJNNC_02496 3e-306 nprB 3.4.24.28 E Peptidase M4
KOILJNNC_02497 9.3e-158 yitS S protein conserved in bacteria
KOILJNNC_02498 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
KOILJNNC_02499 1.4e-72 ipi S Intracellular proteinase inhibitor
KOILJNNC_02500 1.2e-17 S Protein of unknown function (DUF3813)
KOILJNNC_02502 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
KOILJNNC_02503 5.5e-141 yjfP S COG1073 Hydrolases of the alpha beta superfamily
KOILJNNC_02504 6.2e-51 yitW S metal-sulfur cluster biosynthetic enzyme
KOILJNNC_02505 1.5e-22 pilT S Proteolipid membrane potential modulator
KOILJNNC_02506 1.7e-268 yitY C D-arabinono-1,4-lactone oxidase
KOILJNNC_02507 3.4e-89 norB G Major Facilitator Superfamily
KOILJNNC_02508 2.1e-196 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KOILJNNC_02509 2e-230 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KOILJNNC_02510 1.2e-135 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
KOILJNNC_02511 9.2e-217 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
KOILJNNC_02512 3.3e-205 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KOILJNNC_02513 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
KOILJNNC_02514 1.1e-175 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KOILJNNC_02515 9.5e-28 yjzC S YjzC-like protein
KOILJNNC_02516 2.3e-16 yjzD S Protein of unknown function (DUF2929)
KOILJNNC_02517 6.2e-142 yjaU I carboxylic ester hydrolase activity
KOILJNNC_02518 7.3e-103 yjaV
KOILJNNC_02519 2.5e-183 med S Transcriptional activator protein med
KOILJNNC_02520 7.3e-26 comZ S ComZ
KOILJNNC_02521 5e-21 yjzB
KOILJNNC_02522 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KOILJNNC_02523 4e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOILJNNC_02524 1.8e-147 yjaZ O Zn-dependent protease
KOILJNNC_02525 1.8e-184 appD P Belongs to the ABC transporter superfamily
KOILJNNC_02526 3.6e-185 appF E Belongs to the ABC transporter superfamily
KOILJNNC_02527 5.9e-286 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
KOILJNNC_02528 7.7e-169 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02529 1e-162 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02530 5e-147 yjbA S Belongs to the UPF0736 family
KOILJNNC_02531 8e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
KOILJNNC_02532 0.0 oppA E ABC transporter substrate-binding protein
KOILJNNC_02533 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02534 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02535 6.8e-198 oppD P Belongs to the ABC transporter superfamily
KOILJNNC_02536 5.5e-172 oppF E Belongs to the ABC transporter superfamily
KOILJNNC_02537 7e-210 yjbB EGP Major Facilitator Superfamily
KOILJNNC_02538 2.6e-103 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_02539 3.5e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
KOILJNNC_02540 1.7e-111 yjbE P Integral membrane protein TerC family
KOILJNNC_02541 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
KOILJNNC_02542 4e-220 yjbF S Competence protein
KOILJNNC_02543 0.0 pepF E oligoendopeptidase F
KOILJNNC_02544 1.8e-20
KOILJNNC_02545 1.2e-168 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
KOILJNNC_02546 1.4e-71 yjbI S Bacterial-like globin
KOILJNNC_02547 4.7e-89 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
KOILJNNC_02548 9.2e-101 yjbK S protein conserved in bacteria
KOILJNNC_02549 9.3e-62 yjbL S Belongs to the UPF0738 family
KOILJNNC_02550 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
KOILJNNC_02551 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KOILJNNC_02552 2.6e-158 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOILJNNC_02553 4.3e-127 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
KOILJNNC_02554 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
KOILJNNC_02555 7.6e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KOILJNNC_02556 1.4e-107 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
KOILJNNC_02557 4.4e-216 thiO 1.4.3.19 E Glycine oxidase
KOILJNNC_02558 1.5e-29 thiS H thiamine diphosphate biosynthetic process
KOILJNNC_02559 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
KOILJNNC_02560 1.9e-186 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KOILJNNC_02561 7.6e-149 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
KOILJNNC_02562 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
KOILJNNC_02563 5.9e-54 yjbX S Spore coat protein
KOILJNNC_02564 5.2e-83 cotZ S Spore coat protein
KOILJNNC_02565 3.4e-96 cotY S Spore coat protein Z
KOILJNNC_02566 6.4e-77 cotX S Spore Coat Protein X and V domain
KOILJNNC_02567 8.5e-32 cotW
KOILJNNC_02568 2.3e-55 cotV S Spore Coat Protein X and V domain
KOILJNNC_02569 4.3e-56 yjcA S Protein of unknown function (DUF1360)
KOILJNNC_02572 2.9e-38 spoVIF S Stage VI sporulation protein F
KOILJNNC_02573 0.0 yjcD 3.6.4.12 L DNA helicase
KOILJNNC_02574 1.7e-38
KOILJNNC_02575 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_02576 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
KOILJNNC_02577 7e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
KOILJNNC_02578 1.5e-214 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KOILJNNC_02579 6.5e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
KOILJNNC_02580 1.7e-96 rimJ 2.3.1.128 J Alanine acetyltransferase
KOILJNNC_02581 1.3e-106 yjcL S Protein of unknown function (DUF819)
KOILJNNC_02582 1.2e-95 yjcL S Protein of unknown function (DUF819)
KOILJNNC_02586 2.7e-190 S Putative amidase domain
KOILJNNC_02587 1.3e-43 yjcN
KOILJNNC_02590 1.2e-79 L Transposase
KOILJNNC_02591 5.9e-13
KOILJNNC_02592 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
KOILJNNC_02593 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_02595 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
KOILJNNC_02596 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
KOILJNNC_02597 2.8e-187 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOILJNNC_02598 2.2e-48 yjdF S Protein of unknown function (DUF2992)
KOILJNNC_02599 3.8e-90 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
KOILJNNC_02601 2.2e-79 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KOILJNNC_02602 7.1e-29 S Domain of unknown function (DUF4177)
KOILJNNC_02603 1.5e-50 yjdJ S Domain of unknown function (DUF4306)
KOILJNNC_02604 1.6e-174 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KOILJNNC_02606 1.1e-264 xynD 3.5.1.104 G Polysaccharide deacetylase
KOILJNNC_02607 1.8e-81 S Protein of unknown function (DUF2690)
KOILJNNC_02608 2.3e-20 yjfB S Putative motility protein
KOILJNNC_02609 2.6e-166 yjfC O Predicted Zn-dependent protease (DUF2268)
KOILJNNC_02610 1.2e-45 T PhoQ Sensor
KOILJNNC_02611 2e-103 yjgB S Domain of unknown function (DUF4309)
KOILJNNC_02612 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
KOILJNNC_02613 3.7e-94 yjgD S Protein of unknown function (DUF1641)
KOILJNNC_02614 5.9e-10 S Domain of unknown function (DUF4352)
KOILJNNC_02615 3.6e-111 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
KOILJNNC_02617 3.7e-221 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
KOILJNNC_02618 5e-218 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KOILJNNC_02619 8.2e-30
KOILJNNC_02620 1.3e-140 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
KOILJNNC_02621 1.6e-121 ybbM S transport system, permease component
KOILJNNC_02622 4.4e-135 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
KOILJNNC_02623 1e-40 yjlA EG Putative multidrug resistance efflux transporter
KOILJNNC_02624 2.2e-90 yjlB S Cupin domain
KOILJNNC_02625 7.1e-66 yjlC S Protein of unknown function (DUF1641)
KOILJNNC_02626 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
KOILJNNC_02627 3e-278 uxaC 5.3.1.12 G glucuronate isomerase
KOILJNNC_02628 1.6e-247 yjmB G symporter YjmB
KOILJNNC_02629 1.8e-187 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
KOILJNNC_02630 2.3e-187 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
KOILJNNC_02631 1.2e-213 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
KOILJNNC_02632 1.2e-152 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
KOILJNNC_02633 4.1e-226 exuT G Sugar (and other) transporter
KOILJNNC_02634 6.8e-184 exuR K transcriptional
KOILJNNC_02635 3.4e-285 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
KOILJNNC_02636 8.7e-284 uxaA 4.2.1.7, 4.4.1.24 G Altronate
KOILJNNC_02637 7.4e-130 MA20_18170 S membrane transporter protein
KOILJNNC_02638 2.3e-78 yjoA S DinB family
KOILJNNC_02639 1.4e-245 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
KOILJNNC_02640 1e-212 S response regulator aspartate phosphatase
KOILJNNC_02642 6e-23 S YCII-related domain
KOILJNNC_02643 1.7e-168 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
KOILJNNC_02644 1.8e-60 yjqA S Bacterial PH domain
KOILJNNC_02645 2.1e-111 yjqB S Pfam:DUF867
KOILJNNC_02646 1.3e-159 ydbD P Catalase
KOILJNNC_02647 2.3e-110 xkdA E IrrE N-terminal-like domain
KOILJNNC_02648 9.2e-56 xre K Helix-turn-helix XRE-family like proteins
KOILJNNC_02650 3.9e-156 xkdB K sequence-specific DNA binding
KOILJNNC_02651 4.1e-118 xkdC L Bacterial dnaA protein
KOILJNNC_02654 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
KOILJNNC_02655 3.5e-83 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
KOILJNNC_02656 1.4e-139 xtmA L phage terminase small subunit
KOILJNNC_02657 1.4e-253 xtmB S phage terminase, large subunit
KOILJNNC_02658 1.6e-285 yqbA S portal protein
KOILJNNC_02659 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
KOILJNNC_02660 1.7e-168 xkdG S Phage capsid family
KOILJNNC_02661 9.6e-62 yqbG S Protein of unknown function (DUF3199)
KOILJNNC_02662 7.3e-64 yqbH S Domain of unknown function (DUF3599)
KOILJNNC_02663 2.9e-87 xkdI S Bacteriophage HK97-gp10, putative tail-component
KOILJNNC_02664 9.3e-77 xkdJ
KOILJNNC_02665 7.2e-256 xkdK S Phage tail sheath C-terminal domain
KOILJNNC_02666 6.1e-76 xkdM S Phage tail tube protein
KOILJNNC_02667 1e-75 S Phage XkdN-like tail assembly chaperone protein, TAC
KOILJNNC_02668 0.0 xkdO L Transglycosylase SLT domain
KOILJNNC_02669 3.7e-122 xkdP S Lysin motif
KOILJNNC_02670 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
KOILJNNC_02671 2.1e-39 xkdR S Protein of unknown function (DUF2577)
KOILJNNC_02672 8.2e-70 xkdS S Protein of unknown function (DUF2634)
KOILJNNC_02673 3e-190 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
KOILJNNC_02674 3.2e-101 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
KOILJNNC_02675 8.7e-41
KOILJNNC_02676 0.0
KOILJNNC_02677 2.7e-44 xkdW S XkdW protein
KOILJNNC_02678 5.5e-22 xkdX
KOILJNNC_02679 2.8e-154 xepA
KOILJNNC_02680 2.8e-39 xhlA S Haemolysin XhlA
KOILJNNC_02681 9.3e-40 xhlB S SPP1 phage holin
KOILJNNC_02682 4.5e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KOILJNNC_02683 6.7e-23 spoIISB S Stage II sporulation protein SB
KOILJNNC_02684 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
KOILJNNC_02685 5.8e-175 pit P phosphate transporter
KOILJNNC_02686 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
KOILJNNC_02687 1.2e-241 steT E amino acid
KOILJNNC_02688 4.6e-182 mhqA E COG0346 Lactoylglutathione lyase and related lyases
KOILJNNC_02690 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KOILJNNC_02691 3.8e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_02693 2e-210 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KOILJNNC_02694 8.2e-135 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
KOILJNNC_02695 7.4e-152 dppA E D-aminopeptidase
KOILJNNC_02696 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02697 3.3e-175 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
KOILJNNC_02698 2.4e-189 dppD P Belongs to the ABC transporter superfamily
KOILJNNC_02699 0.0 dppE E ABC transporter substrate-binding protein
KOILJNNC_02701 2.9e-176 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
KOILJNNC_02702 4.8e-199 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KOILJNNC_02703 1.3e-170 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
KOILJNNC_02704 5.5e-186 ykfD E Belongs to the ABC transporter superfamily
KOILJNNC_02705 4.5e-202 pgl 3.1.1.31 G 6-phosphogluconolactonase
KOILJNNC_02706 6.5e-159 ykgA E Amidinotransferase
KOILJNNC_02707 1.3e-91 ykhA 3.1.2.20 I Acyl-CoA hydrolase
KOILJNNC_02708 2.8e-224 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KOILJNNC_02709 1.5e-09
KOILJNNC_02710 3.9e-128 ykjA S Protein of unknown function (DUF421)
KOILJNNC_02711 2.6e-97 ykkA S Protein of unknown function (DUF664)
KOILJNNC_02712 1.2e-96 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KOILJNNC_02713 1.7e-54 ykkC P Multidrug resistance protein
KOILJNNC_02714 9.1e-50 ykkD P Multidrug resistance protein
KOILJNNC_02715 8.6e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
KOILJNNC_02716 2e-200 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KOILJNNC_02717 9e-226 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KOILJNNC_02718 1.3e-70 ohrA O Organic hydroperoxide resistance protein
KOILJNNC_02719 9.7e-74 ohrR K COG1846 Transcriptional regulators
KOILJNNC_02720 4.2e-71 ohrB O Organic hydroperoxide resistance protein
KOILJNNC_02721 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
KOILJNNC_02722 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KOILJNNC_02723 1.5e-175 isp O Belongs to the peptidase S8 family
KOILJNNC_02724 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KOILJNNC_02725 2.9e-134 ykoC P Cobalt transport protein
KOILJNNC_02726 4.1e-303 P ABC transporter, ATP-binding protein
KOILJNNC_02727 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
KOILJNNC_02728 2.6e-76 ykoF S YKOF-related Family
KOILJNNC_02729 7.9e-123 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_02730 3e-243 ykoH 2.7.13.3 T Histidine kinase
KOILJNNC_02731 8.9e-111 ykoI S Peptidase propeptide and YPEB domain
KOILJNNC_02732 6.3e-85 ykoJ S Peptidase propeptide and YPEB domain
KOILJNNC_02735 2.2e-222 mgtE P Acts as a magnesium transporter
KOILJNNC_02736 1.4e-53 tnrA K transcriptional
KOILJNNC_02737 5.9e-18
KOILJNNC_02738 6.9e-26 ykoL
KOILJNNC_02739 1.3e-81 mhqR K transcriptional
KOILJNNC_02740 3.8e-212 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
KOILJNNC_02741 3.2e-98 ykoP G polysaccharide deacetylase
KOILJNNC_02742 3e-153 ykoQ S Calcineurin-like phosphoesterase superfamily domain
KOILJNNC_02743 0.0 ykoS
KOILJNNC_02744 6.2e-185 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_02745 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
KOILJNNC_02746 1e-159 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
KOILJNNC_02747 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
KOILJNNC_02748 3.5e-109 ykoX S membrane-associated protein
KOILJNNC_02749 3.7e-140 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
KOILJNNC_02750 9.5e-130 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_02751 1.7e-109 rsgI S Anti-sigma factor N-terminus
KOILJNNC_02752 1.9e-26 sspD S small acid-soluble spore protein
KOILJNNC_02753 1.5e-124 ykrK S Domain of unknown function (DUF1836)
KOILJNNC_02754 3.5e-155 htpX O Belongs to the peptidase M48B family
KOILJNNC_02755 2.2e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
KOILJNNC_02756 1.2e-10 ydfR S Protein of unknown function (DUF421)
KOILJNNC_02757 4.5e-22 ykzE
KOILJNNC_02758 1.4e-189 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
KOILJNNC_02759 0.0 kinE 2.7.13.3 T Histidine kinase
KOILJNNC_02760 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KOILJNNC_02762 3.7e-196 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KOILJNNC_02763 1.7e-229 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
KOILJNNC_02764 6.6e-150 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
KOILJNNC_02765 1.7e-229 mtnE 2.6.1.83 E Aminotransferase
KOILJNNC_02766 6.5e-229 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
KOILJNNC_02767 3.2e-135 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
KOILJNNC_02768 8e-114 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
KOILJNNC_02769 8.4e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KOILJNNC_02770 2.9e-51 XK27_09985 S Protein of unknown function (DUF1232)
KOILJNNC_02771 7.5e-10 S Spo0E like sporulation regulatory protein
KOILJNNC_02772 1.5e-63 eag
KOILJNNC_02773 4.8e-274 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
KOILJNNC_02774 1.3e-75 ykvE K transcriptional
KOILJNNC_02775 2.5e-125 motB N Flagellar motor protein
KOILJNNC_02776 1e-137 motA N flagellar motor
KOILJNNC_02777 0.0 clpE O Belongs to the ClpA ClpB family
KOILJNNC_02778 3.3e-181 ykvI S membrane
KOILJNNC_02779 3.6e-125 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KOILJNNC_02780 1e-78 queD 4.1.2.50, 4.2.3.12 H synthase
KOILJNNC_02781 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
KOILJNNC_02782 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KOILJNNC_02783 7.6e-61 ykvN K HxlR-like helix-turn-helix
KOILJNNC_02784 3.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_02785 4.9e-215 ykvP 3.5.1.28 M Glycosyl transferases group 1
KOILJNNC_02786 3.5e-35 3.5.1.104 M LysM domain
KOILJNNC_02787 5.3e-162 G Glycosyl hydrolases family 18
KOILJNNC_02788 4.8e-45 ykvR S Protein of unknown function (DUF3219)
KOILJNNC_02789 6e-25 ykvS S protein conserved in bacteria
KOILJNNC_02790 1e-27
KOILJNNC_02791 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
KOILJNNC_02792 1.7e-238 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_02793 2.4e-89 stoA CO thiol-disulfide
KOILJNNC_02794 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
KOILJNNC_02795 2.3e-09
KOILJNNC_02796 2.5e-208 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
KOILJNNC_02797 6.4e-179 ykvZ 5.1.1.1 K Transcriptional regulator
KOILJNNC_02798 7.6e-128 glcT K antiterminator
KOILJNNC_02799 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_02800 2.1e-39 ptsH G phosphocarrier protein HPr
KOILJNNC_02801 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KOILJNNC_02802 7.2e-39 splA S Transcriptional regulator
KOILJNNC_02803 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
KOILJNNC_02804 5.4e-127 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
KOILJNNC_02805 9.1e-257 mcpC NT chemotaxis protein
KOILJNNC_02806 8.6e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
KOILJNNC_02807 4.6e-14 vgb H Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid
KOILJNNC_02808 1.8e-123 ykwD J protein with SCP PR1 domains
KOILJNNC_02809 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
KOILJNNC_02810 0.0 pilS 2.7.13.3 T Histidine kinase
KOILJNNC_02811 6.3e-221 patA 2.6.1.1 E Aminotransferase
KOILJNNC_02812 3.7e-15
KOILJNNC_02813 6.2e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
KOILJNNC_02814 4.9e-84 ykyB S YkyB-like protein
KOILJNNC_02815 2.8e-238 ykuC EGP Major facilitator Superfamily
KOILJNNC_02816 8.6e-84 ykuD S protein conserved in bacteria
KOILJNNC_02817 7.4e-163 ykuE S Metallophosphoesterase
KOILJNNC_02818 2.9e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_02819 5.2e-234 ykuI T Diguanylate phosphodiesterase
KOILJNNC_02820 3.9e-37 ykuJ S protein conserved in bacteria
KOILJNNC_02821 2.2e-93 ykuK S Ribonuclease H-like
KOILJNNC_02822 3.9e-27 ykzF S Antirepressor AbbA
KOILJNNC_02823 1.6e-76 ykuL S CBS domain
KOILJNNC_02824 3.5e-168 ccpC K Transcriptional regulator
KOILJNNC_02825 1.7e-84 fld C Flavodoxin domain
KOILJNNC_02826 2.6e-174 ykuO
KOILJNNC_02827 3.9e-78 fld C Flavodoxin
KOILJNNC_02828 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
KOILJNNC_02829 1.2e-213 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
KOILJNNC_02830 9e-37 ykuS S Belongs to the UPF0180 family
KOILJNNC_02831 5.7e-141 ykuT M Mechanosensitive ion channel
KOILJNNC_02832 3.9e-101 ykuU O Alkyl hydroperoxide reductase
KOILJNNC_02833 7e-80 ykuV CO thiol-disulfide
KOILJNNC_02834 5.8e-95 rok K Repressor of ComK
KOILJNNC_02835 2.1e-145 yknT
KOILJNNC_02836 1.1e-109 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
KOILJNNC_02837 3.8e-190 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
KOILJNNC_02838 1.4e-242 moeA 2.10.1.1 H molybdopterin
KOILJNNC_02839 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
KOILJNNC_02840 3.2e-83 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
KOILJNNC_02841 8.3e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KOILJNNC_02842 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
KOILJNNC_02843 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
KOILJNNC_02844 4.7e-115 yknW S Yip1 domain
KOILJNNC_02845 1.2e-157 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KOILJNNC_02846 2.5e-124 macB V ABC transporter, ATP-binding protein
KOILJNNC_02847 8.1e-208 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
KOILJNNC_02848 3.1e-136 fruR K Transcriptional regulator
KOILJNNC_02849 1.8e-167 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
KOILJNNC_02850 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
KOILJNNC_02851 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KOILJNNC_02852 8.1e-39 ykoA
KOILJNNC_02853 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KOILJNNC_02854 2.4e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOILJNNC_02855 1.3e-237 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
KOILJNNC_02856 1.1e-12 S Uncharacterized protein YkpC
KOILJNNC_02857 1.7e-182 mreB D Rod-share determining protein MreBH
KOILJNNC_02858 1.5e-43 abrB K of stationary sporulation gene expression
KOILJNNC_02859 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
KOILJNNC_02860 7.2e-155 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
KOILJNNC_02861 2e-115 ktrA P COG0569 K transport systems, NAD-binding component
KOILJNNC_02862 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KOILJNNC_02863 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOILJNNC_02864 8.2e-31 ykzG S Belongs to the UPF0356 family
KOILJNNC_02865 1.4e-147 ykrA S hydrolases of the HAD superfamily
KOILJNNC_02866 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOILJNNC_02868 2e-115 recN L Putative cell-wall binding lipoprotein
KOILJNNC_02869 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KOILJNNC_02870 4.9e-179 pdhB 1.2.4.1 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KOILJNNC_02871 3.2e-229 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOILJNNC_02872 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KOILJNNC_02873 1.3e-63 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
KOILJNNC_02874 2.7e-10 S SR1 protein
KOILJNNC_02875 3.8e-276 speA 4.1.1.19 E Arginine
KOILJNNC_02876 1.6e-42 yktA S Belongs to the UPF0223 family
KOILJNNC_02877 2.1e-117 yktB S Belongs to the UPF0637 family
KOILJNNC_02878 7.1e-26 ykzI
KOILJNNC_02879 3.9e-150 suhB 3.1.3.25 G Inositol monophosphatase
KOILJNNC_02880 6.9e-78 ykzC S Acetyltransferase (GNAT) family
KOILJNNC_02881 2.3e-113 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KOILJNNC_02882 3.1e-38 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KOILJNNC_02883 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
KOILJNNC_02884 0.0 ylaA
KOILJNNC_02885 7.8e-42 ylaB
KOILJNNC_02886 2.1e-88 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_02887 2e-11 sigC S Putative zinc-finger
KOILJNNC_02888 2.6e-37 ylaE
KOILJNNC_02889 8.2e-22 S Family of unknown function (DUF5325)
KOILJNNC_02890 0.0 typA T GTP-binding protein TypA
KOILJNNC_02891 4.2e-47 ylaH S YlaH-like protein
KOILJNNC_02892 2.5e-32 ylaI S protein conserved in bacteria
KOILJNNC_02893 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
KOILJNNC_02894 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
KOILJNNC_02895 1.1e-83 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KOILJNNC_02896 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
KOILJNNC_02897 8.7e-44 ylaN S Belongs to the UPF0358 family
KOILJNNC_02898 9.4e-212 ftsW D Belongs to the SEDS family
KOILJNNC_02899 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
KOILJNNC_02900 7.7e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
KOILJNNC_02901 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
KOILJNNC_02902 1.8e-190 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
KOILJNNC_02903 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KOILJNNC_02904 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
KOILJNNC_02905 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
KOILJNNC_02906 7.5e-166 ctaG S cytochrome c oxidase
KOILJNNC_02907 2e-61 ylbA S YugN-like family
KOILJNNC_02908 1.3e-73 ylbB T COG0517 FOG CBS domain
KOILJNNC_02909 1.8e-198 ylbC S protein with SCP PR1 domains
KOILJNNC_02910 3.4e-62 ylbD S Putative coat protein
KOILJNNC_02911 1.5e-36 ylbE S YlbE-like protein
KOILJNNC_02912 1.8e-75 ylbF S Belongs to the UPF0342 family
KOILJNNC_02913 7.5e-39 ylbG S UPF0298 protein
KOILJNNC_02914 9.2e-98 rsmD 2.1.1.171 L Methyltransferase
KOILJNNC_02915 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KOILJNNC_02916 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
KOILJNNC_02917 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
KOILJNNC_02918 6.3e-185 ylbL T Belongs to the peptidase S16 family
KOILJNNC_02919 3.9e-229 ylbM S Belongs to the UPF0348 family
KOILJNNC_02921 3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
KOILJNNC_02922 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
KOILJNNC_02923 2.2e-73 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
KOILJNNC_02924 1.5e-88 ylbP K n-acetyltransferase
KOILJNNC_02925 5.2e-167 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KOILJNNC_02926 4.6e-307 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KOILJNNC_02927 2.9e-78 mraZ K Belongs to the MraZ family
KOILJNNC_02928 1.6e-171 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
KOILJNNC_02929 3.7e-44 ftsL D Essential cell division protein
KOILJNNC_02930 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
KOILJNNC_02931 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
KOILJNNC_02932 1.2e-280 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KOILJNNC_02933 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KOILJNNC_02934 7.7e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KOILJNNC_02935 5.7e-186 spoVE D Belongs to the SEDS family
KOILJNNC_02936 4.3e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KOILJNNC_02937 1.5e-166 murB 1.3.1.98 M cell wall formation
KOILJNNC_02938 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
KOILJNNC_02939 4.1e-103 ylxW S protein conserved in bacteria
KOILJNNC_02940 1e-102 ylxX S protein conserved in bacteria
KOILJNNC_02941 6.2e-58 sbp S small basic protein
KOILJNNC_02942 7e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
KOILJNNC_02943 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KOILJNNC_02944 0.0 bpr O COG1404 Subtilisin-like serine proteases
KOILJNNC_02946 1.2e-171 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
KOILJNNC_02947 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_02948 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_02949 6.9e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
KOILJNNC_02950 7.1e-250 argE 3.5.1.16 E Acetylornithine deacetylase
KOILJNNC_02951 2.4e-37 ylmC S sporulation protein
KOILJNNC_02952 2.4e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
KOILJNNC_02953 6.5e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KOILJNNC_02954 1.5e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
KOILJNNC_02955 2.8e-39 yggT S membrane
KOILJNNC_02956 3.3e-138 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
KOILJNNC_02957 2.6e-67 divIVA D Cell division initiation protein
KOILJNNC_02958 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KOILJNNC_02959 1.3e-63 dksA T COG1734 DnaK suppressor protein
KOILJNNC_02960 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KOILJNNC_02961 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
KOILJNNC_02962 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KOILJNNC_02963 5.4e-229 pyrP F Xanthine uracil
KOILJNNC_02964 3.4e-166 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
KOILJNNC_02965 9.2e-250 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
KOILJNNC_02966 1.9e-211 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
KOILJNNC_02967 0.0 carB 6.3.5.5 F Belongs to the CarB family
KOILJNNC_02968 2e-143 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
KOILJNNC_02969 4.6e-174 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
KOILJNNC_02970 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
KOILJNNC_02971 3.3e-115 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KOILJNNC_02973 7.7e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
KOILJNNC_02974 4.1e-179 cysP P phosphate transporter
KOILJNNC_02975 6.5e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
KOILJNNC_02976 1.6e-108 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
KOILJNNC_02977 8.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KOILJNNC_02978 4.1e-144 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
KOILJNNC_02979 5.3e-81 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
KOILJNNC_02980 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
KOILJNNC_02981 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
KOILJNNC_02982 2.4e-156 yloC S stress-induced protein
KOILJNNC_02983 1.5e-40 ylzA S Belongs to the UPF0296 family
KOILJNNC_02984 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
KOILJNNC_02985 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
KOILJNNC_02986 1.8e-223 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KOILJNNC_02987 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOILJNNC_02988 6.6e-84 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
KOILJNNC_02989 4e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KOILJNNC_02990 2.3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KOILJNNC_02991 5.3e-206 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
KOILJNNC_02992 2.7e-140 stp 3.1.3.16 T phosphatase
KOILJNNC_02993 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
KOILJNNC_02994 3.3e-169 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
KOILJNNC_02995 1.2e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
KOILJNNC_02996 7.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
KOILJNNC_02997 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
KOILJNNC_02998 5.5e-59 asp S protein conserved in bacteria
KOILJNNC_02999 1.9e-300 yloV S kinase related to dihydroxyacetone kinase
KOILJNNC_03000 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
KOILJNNC_03001 1.6e-155 sdaAA 4.3.1.17 E L-serine dehydratase
KOILJNNC_03002 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KOILJNNC_03003 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
KOILJNNC_03004 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
KOILJNNC_03005 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KOILJNNC_03006 5.1e-128 IQ reductase
KOILJNNC_03007 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
KOILJNNC_03008 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
KOILJNNC_03009 0.0 smc D Required for chromosome condensation and partitioning
KOILJNNC_03010 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
KOILJNNC_03011 2.9e-87
KOILJNNC_03012 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
KOILJNNC_03013 1e-235 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KOILJNNC_03014 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
KOILJNNC_03015 4.5e-36 ylqC S Belongs to the UPF0109 family
KOILJNNC_03016 6.3e-61 ylqD S YlqD protein
KOILJNNC_03017 2e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KOILJNNC_03018 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
KOILJNNC_03019 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
KOILJNNC_03020 4.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KOILJNNC_03021 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KOILJNNC_03022 7.7e-284 ylqG
KOILJNNC_03023 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
KOILJNNC_03024 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
KOILJNNC_03025 3.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KOILJNNC_03026 3e-167 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
KOILJNNC_03027 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOILJNNC_03028 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KOILJNNC_03029 2.5e-169 xerC L tyrosine recombinase XerC
KOILJNNC_03030 7.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KOILJNNC_03031 1.3e-249 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KOILJNNC_03032 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KOILJNNC_03033 1.5e-62 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
KOILJNNC_03034 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
KOILJNNC_03035 1.9e-31 fliE N Flagellar hook-basal body
KOILJNNC_03036 2.6e-254 fliF N The M ring may be actively involved in energy transduction
KOILJNNC_03037 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KOILJNNC_03038 1.3e-105 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
KOILJNNC_03039 7.2e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
KOILJNNC_03040 7.2e-69 fliJ N Flagellar biosynthesis chaperone
KOILJNNC_03041 2.2e-36 ylxF S MgtE intracellular N domain
KOILJNNC_03042 4.9e-215 fliK N Flagellar hook-length control protein
KOILJNNC_03043 2.3e-72 flgD N Flagellar basal body rod modification protein
KOILJNNC_03044 1.9e-136 flgG N Flagellar basal body rod
KOILJNNC_03045 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
KOILJNNC_03046 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
KOILJNNC_03047 5.9e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
KOILJNNC_03048 6.1e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
KOILJNNC_03049 5.1e-95 fliZ N Flagellar biosynthesis protein, FliO
KOILJNNC_03050 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
KOILJNNC_03051 2.2e-36 fliQ N Role in flagellar biosynthesis
KOILJNNC_03052 3.6e-132 fliR N Flagellar biosynthetic protein FliR
KOILJNNC_03053 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KOILJNNC_03054 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
KOILJNNC_03055 1.2e-200 flhF N Flagellar biosynthesis regulator FlhF
KOILJNNC_03056 6.3e-157 flhG D Belongs to the ParA family
KOILJNNC_03057 2.2e-196 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
KOILJNNC_03058 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
KOILJNNC_03059 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
KOILJNNC_03060 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
KOILJNNC_03061 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
KOILJNNC_03062 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_03063 3.1e-76 ylxL
KOILJNNC_03064 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
KOILJNNC_03065 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KOILJNNC_03066 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
KOILJNNC_03067 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
KOILJNNC_03068 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KOILJNNC_03069 4.5e-138 cdsA 2.7.7.41 S Belongs to the CDS family
KOILJNNC_03070 3e-215 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
KOILJNNC_03071 7.7e-233 rasP M zinc metalloprotease
KOILJNNC_03072 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
KOILJNNC_03073 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOILJNNC_03074 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
KOILJNNC_03075 1.1e-203 nusA K Participates in both transcription termination and antitermination
KOILJNNC_03076 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
KOILJNNC_03077 9e-47 ylxQ J ribosomal protein
KOILJNNC_03078 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KOILJNNC_03079 3e-44 ylxP S protein conserved in bacteria
KOILJNNC_03080 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KOILJNNC_03081 1.5e-172 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KOILJNNC_03082 6.7e-181 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
KOILJNNC_03083 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KOILJNNC_03084 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
KOILJNNC_03085 2.8e-179 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
KOILJNNC_03086 4.4e-233 pepR S Belongs to the peptidase M16 family
KOILJNNC_03087 2.6e-42 ymxH S YlmC YmxH family
KOILJNNC_03088 3.8e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
KOILJNNC_03089 4.8e-108 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
KOILJNNC_03090 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KOILJNNC_03091 1.7e-221 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
KOILJNNC_03092 5.2e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KOILJNNC_03093 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KOILJNNC_03094 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
KOILJNNC_03095 4.4e-32 S YlzJ-like protein
KOILJNNC_03096 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
KOILJNNC_03097 1.4e-133 ymfC K Transcriptional regulator
KOILJNNC_03098 1.5e-206 ymfD EGP Major facilitator Superfamily
KOILJNNC_03099 2.7e-233 ymfF S Peptidase M16
KOILJNNC_03100 1.4e-242 ymfH S zinc protease
KOILJNNC_03101 4.6e-129 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
KOILJNNC_03102 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
KOILJNNC_03103 2.7e-143 ymfK S Protein of unknown function (DUF3388)
KOILJNNC_03104 1.9e-124 ymfM S protein conserved in bacteria
KOILJNNC_03105 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOILJNNC_03106 9.6e-236 cinA 3.5.1.42 S Belongs to the CinA family
KOILJNNC_03107 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KOILJNNC_03108 8.8e-215 pbpX V Beta-lactamase
KOILJNNC_03109 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
KOILJNNC_03110 1.9e-152 ymdB S protein conserved in bacteria
KOILJNNC_03111 1.2e-36 spoVS S Stage V sporulation protein S
KOILJNNC_03112 5.1e-198 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
KOILJNNC_03113 4.7e-216 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
KOILJNNC_03114 1.7e-295 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KOILJNNC_03115 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
KOILJNNC_03116 2.2e-88 cotE S Spore coat protein
KOILJNNC_03117 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KOILJNNC_03118 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KOILJNNC_03119 4.1e-67 S Regulatory protein YrvL
KOILJNNC_03121 3.5e-97 ymcC S Membrane
KOILJNNC_03122 4.4e-109 pksA K Transcriptional regulator
KOILJNNC_03123 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
KOILJNNC_03124 2.2e-162 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KOILJNNC_03125 2.3e-184 pksD Q Acyl transferase domain
KOILJNNC_03126 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
KOILJNNC_03127 1.4e-37 acpK IQ Phosphopantetheine attachment site
KOILJNNC_03128 6.6e-237 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
KOILJNNC_03129 1.5e-244 pksG 2.3.3.10 I synthase
KOILJNNC_03130 4.2e-141 pksH 4.2.1.18 I enoyl-CoA hydratase
KOILJNNC_03131 6.8e-136 pksI I Belongs to the enoyl-CoA hydratase isomerase family
KOILJNNC_03132 0.0 rhiB IQ polyketide synthase
KOILJNNC_03133 0.0 pfaA Q Polyketide synthase of type I
KOILJNNC_03134 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
KOILJNNC_03135 0.0 dhbF IQ polyketide synthase
KOILJNNC_03136 0.0 pks13 HQ Beta-ketoacyl synthase
KOILJNNC_03137 1.5e-230 cypA C Cytochrome P450
KOILJNNC_03138 4.4e-61 ymzB
KOILJNNC_03139 3.5e-162 ymaE S Metallo-beta-lactamase superfamily
KOILJNNC_03140 2.3e-251 aprX O Belongs to the peptidase S8 family
KOILJNNC_03141 1.9e-07 K Transcriptional regulator
KOILJNNC_03142 2.1e-126 ymaC S Replication protein
KOILJNNC_03143 1.6e-79 ymaD O redox protein, regulator of disulfide bond formation
KOILJNNC_03144 1.5e-53 ebrB P COG2076 Membrane transporters of cations and cationic drugs
KOILJNNC_03145 5.4e-50 ebrA P Small Multidrug Resistance protein
KOILJNNC_03147 2.1e-46 ymaF S YmaF family
KOILJNNC_03148 3.5e-174 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KOILJNNC_03149 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
KOILJNNC_03150 4.5e-22 ymzA
KOILJNNC_03151 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
KOILJNNC_03152 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOILJNNC_03153 1.3e-187 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KOILJNNC_03154 2e-109 ymaB
KOILJNNC_03155 1.2e-114 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KOILJNNC_03156 1.7e-176 spoVK O stage V sporulation protein K
KOILJNNC_03157 7.9e-230 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KOILJNNC_03158 9.7e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
KOILJNNC_03159 3.3e-68 glnR K transcriptional
KOILJNNC_03160 7e-261 glnA 6.3.1.2 E glutamine synthetase
KOILJNNC_03161 1.7e-38 L Arm DNA-binding domain
KOILJNNC_03162 3.4e-82 dnaB 3.6.4.12 L replicative DNA helicase
KOILJNNC_03163 3.9e-23
KOILJNNC_03164 2.2e-17
KOILJNNC_03165 5.8e-10 wecC 1.1.1.336 M ArpU family transcriptional regulator
KOILJNNC_03166 6.1e-26 S FRG
KOILJNNC_03167 5.4e-66 S regulation of transcription, DNA-dependent
KOILJNNC_03168 4.8e-19 N HicA toxin of bacterial toxin-antitoxin,
KOILJNNC_03173 2.4e-43 V HNH endonuclease
KOILJNNC_03174 5.8e-78 L phage terminase small subunit
KOILJNNC_03175 5.8e-17 S Terminase
KOILJNNC_03178 6.5e-10
KOILJNNC_03179 4.3e-30
KOILJNNC_03180 4.3e-68 Q Collagen triple helix repeat (20 copies)
KOILJNNC_03181 7.8e-08
KOILJNNC_03183 4.9e-179 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KOILJNNC_03184 5.2e-84 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
KOILJNNC_03185 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
KOILJNNC_03186 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
KOILJNNC_03187 1.4e-187 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KOILJNNC_03188 0.0 ydiF S ABC transporter
KOILJNNC_03189 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
KOILJNNC_03190 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KOILJNNC_03191 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KOILJNNC_03192 4.1e-125 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KOILJNNC_03193 2.9e-27 ydiK S Domain of unknown function (DUF4305)
KOILJNNC_03194 7.9e-129 ydiL S CAAX protease self-immunity
KOILJNNC_03195 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KOILJNNC_03196 3.7e-280 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
KOILJNNC_03197 5.7e-145 L Belongs to the 'phage' integrase family
KOILJNNC_03198 5.5e-49 xkdA E IrrE N-terminal-like domain
KOILJNNC_03199 1.1e-26 S Short C-terminal domain
KOILJNNC_03200 4.2e-46 xre K Helix-turn-helix XRE-family like proteins
KOILJNNC_03201 1.6e-19 K Helix-turn-helix XRE-family like proteins
KOILJNNC_03202 2e-33
KOILJNNC_03203 4.5e-44 S DNA binding
KOILJNNC_03204 5.4e-69
KOILJNNC_03210 1.2e-97
KOILJNNC_03211 5.8e-69 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
KOILJNNC_03212 9.1e-50 L DnaD domain protein
KOILJNNC_03213 4.4e-80 xkdC L IstB-like ATP binding protein
KOILJNNC_03216 3.7e-47 S Protein of unknown function (DUF1064)
KOILJNNC_03218 3.1e-19 yqaO S Phage-like element PBSX protein XtrA
KOILJNNC_03220 7.3e-76
KOILJNNC_03222 1.4e-126 2.1.1.72 L D12 class N6 adenine-specific DNA methyltransferase
KOILJNNC_03223 3e-09 S Bacillus cereus group antimicrobial protein
KOILJNNC_03225 1e-08
KOILJNNC_03228 1.9e-80 L Transposase
KOILJNNC_03231 2.3e-91 yqaS L DNA packaging
KOILJNNC_03232 1.7e-216 S phage terminase, large subunit
KOILJNNC_03233 4.7e-207 S Phage portal protein, SPP1 Gp6-like
KOILJNNC_03234 1.5e-81 S Phage Mu protein F like protein
KOILJNNC_03236 1.8e-59 S Domain of unknown function (DUF4355)
KOILJNNC_03237 8.3e-144 S Phage capsid family
KOILJNNC_03240 2.4e-28 S Phage gp6-like head-tail connector protein
KOILJNNC_03241 4.8e-28 S Phage head-tail joining protein
KOILJNNC_03242 8.9e-37 S Bacteriophage HK97-gp10, putative tail-component
KOILJNNC_03243 2.3e-29 S Protein of unknown function (DUF3168)
KOILJNNC_03244 3e-34 S Phage tail tube protein
KOILJNNC_03245 4.2e-28 S Phage tail assembly chaperone protein, TAC
KOILJNNC_03247 1.3e-131
KOILJNNC_03248 2e-50
KOILJNNC_03249 1.1e-220 S peptidoglycan catabolic process
KOILJNNC_03254 1.2e-57 S Bacteriophage holin family
KOILJNNC_03255 2e-101 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
KOILJNNC_03258 2.2e-22 K Helix-turn-helix domain
KOILJNNC_03260 2.7e-101 E Pfam:DUF955
KOILJNNC_03261 4.8e-14
KOILJNNC_03262 3.6e-153 ydjC S Abhydrolase domain containing 18
KOILJNNC_03263 0.0 K NB-ARC domain
KOILJNNC_03264 2.7e-199 gutB 1.1.1.14 E Dehydrogenase
KOILJNNC_03265 2.1e-252 gutA G MFS/sugar transport protein
KOILJNNC_03266 6.8e-173 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
KOILJNNC_03267 1.1e-113 pspA KT Phage shock protein A
KOILJNNC_03268 2.2e-177 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KOILJNNC_03269 9.3e-133 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
KOILJNNC_03270 4.1e-149 ydjI S virion core protein (lumpy skin disease virus)
KOILJNNC_03271 2.3e-195 S Ion transport 2 domain protein
KOILJNNC_03272 3.9e-257 iolT EGP Major facilitator Superfamily
KOILJNNC_03273 3.4e-194 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
KOILJNNC_03274 4.5e-64 ydjM M Lytic transglycolase
KOILJNNC_03275 7.7e-154 ydjN U Involved in the tonB-independent uptake of proteins
KOILJNNC_03276 1.2e-34 ydjO S Cold-inducible protein YdjO
KOILJNNC_03277 3.1e-158 ydjP I Alpha/beta hydrolase family
KOILJNNC_03278 1.9e-178 yeaA S Protein of unknown function (DUF4003)
KOILJNNC_03279 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
KOILJNNC_03280 2.2e-252 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_03281 3.8e-154 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOILJNNC_03282 8.6e-176 yeaC S COG0714 MoxR-like ATPases
KOILJNNC_03283 1.3e-221 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
KOILJNNC_03284 0.0 yebA E COG1305 Transglutaminase-like enzymes
KOILJNNC_03285 1.2e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
KOILJNNC_03286 1.7e-211 pbuG S permease
KOILJNNC_03287 2.3e-118 yebC M Membrane
KOILJNNC_03289 4e-93 yebE S UPF0316 protein
KOILJNNC_03290 8e-28 yebG S NETI protein
KOILJNNC_03291 1.3e-82 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KOILJNNC_03292 1.2e-216 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KOILJNNC_03293 2.1e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KOILJNNC_03294 1.1e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
KOILJNNC_03295 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOILJNNC_03296 3.3e-129 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOILJNNC_03297 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KOILJNNC_03298 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KOILJNNC_03299 1.9e-176 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
KOILJNNC_03300 2.4e-104 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KOILJNNC_03301 3.5e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
KOILJNNC_03302 3.8e-232 purD 6.3.4.13 F Belongs to the GARS family
KOILJNNC_03303 1e-72 K helix_turn_helix ASNC type
KOILJNNC_03304 6.8e-229 yjeH E Amino acid permease
KOILJNNC_03305 2.7e-27 S Protein of unknown function (DUF2892)
KOILJNNC_03306 0.0 yerA 3.5.4.2 F adenine deaminase
KOILJNNC_03307 2.4e-189 yerB S Protein of unknown function (DUF3048) C-terminal domain
KOILJNNC_03308 4.8e-51 yerC S protein conserved in bacteria
KOILJNNC_03309 1.1e-302 yerD 1.4.7.1 E Belongs to the glutamate synthase family
KOILJNNC_03311 1.4e-124 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KOILJNNC_03312 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
KOILJNNC_03313 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KOILJNNC_03314 7e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
KOILJNNC_03315 1.3e-195 yerI S homoserine kinase type II (protein kinase fold)
KOILJNNC_03316 3.6e-123 sapB S MgtC SapB transporter
KOILJNNC_03317 3.2e-262 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOILJNNC_03318 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOILJNNC_03319 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
KOILJNNC_03320 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KOILJNNC_03321 5.9e-144 yerO K Transcriptional regulator
KOILJNNC_03322 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KOILJNNC_03323 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
KOILJNNC_03324 6.4e-249 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOILJNNC_03325 6.7e-68 L Recombinase zinc beta ribbon domain
KOILJNNC_03327 5.2e-114 KLT Protein tyrosine kinase
KOILJNNC_03328 4.7e-47 S Domain of unknown function (DUF4062)
KOILJNNC_03329 1.6e-114 S Domain of unknown function (DUF4935)
KOILJNNC_03330 4.7e-92 S response regulator aspartate phosphatase
KOILJNNC_03332 1.3e-42 S Immunity protein 22
KOILJNNC_03333 2.5e-187 yobL S Bacterial EndoU nuclease
KOILJNNC_03334 6.9e-173 3.4.24.40 CO amine dehydrogenase activity
KOILJNNC_03335 1.5e-38
KOILJNNC_03336 4.3e-211 S Tetratricopeptide repeat
KOILJNNC_03338 2.7e-126 yeeN K transcriptional regulatory protein
KOILJNNC_03340 9.4e-101 dhaR3 K Transcriptional regulator
KOILJNNC_03341 3.5e-79 yesE S SnoaL-like domain
KOILJNNC_03342 4.9e-143 yesF GM NAD(P)H-binding
KOILJNNC_03343 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
KOILJNNC_03344 1.5e-45 cotJB S CotJB protein
KOILJNNC_03345 5.2e-104 cotJC P Spore Coat
KOILJNNC_03346 6e-102 yesJ K Acetyltransferase (GNAT) family
KOILJNNC_03348 2.6e-101 yesL S Protein of unknown function, DUF624
KOILJNNC_03349 0.0 yesM 2.7.13.3 T Histidine kinase
KOILJNNC_03350 3.6e-202 yesN K helix_turn_helix, arabinose operon control protein
KOILJNNC_03351 1.6e-246 yesO G Bacterial extracellular solute-binding protein
KOILJNNC_03352 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
KOILJNNC_03353 2.9e-162 yesQ P Binding-protein-dependent transport system inner membrane component
KOILJNNC_03354 1.5e-197 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
KOILJNNC_03355 0.0 yesS K Transcriptional regulator
KOILJNNC_03356 7.2e-132 E GDSL-like Lipase/Acylhydrolase
KOILJNNC_03357 1.1e-129 yesU S Domain of unknown function (DUF1961)
KOILJNNC_03358 1.1e-112 yesV S Protein of unknown function, DUF624
KOILJNNC_03359 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KOILJNNC_03360 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
KOILJNNC_03361 1.5e-123 yesY E GDSL-like Lipase/Acylhydrolase
KOILJNNC_03362 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
KOILJNNC_03363 0.0 yetA
KOILJNNC_03364 6.2e-290 lplA G Bacterial extracellular solute-binding protein
KOILJNNC_03365 8.5e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
KOILJNNC_03366 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
KOILJNNC_03367 3.2e-253 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
KOILJNNC_03368 4e-122 yetF S membrane
KOILJNNC_03369 8.2e-54 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
KOILJNNC_03370 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
KOILJNNC_03371 2.2e-34
KOILJNNC_03372 8.4e-146 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
KOILJNNC_03373 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
KOILJNNC_03374 2e-104 yetJ S Belongs to the BI1 family
KOILJNNC_03375 6.2e-53 yetL K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_03376 2.3e-75
KOILJNNC_03377 4.4e-21
KOILJNNC_03378 2.8e-21 S Uncharacterised protein conserved in bacteria (DUF2326)
KOILJNNC_03379 3.7e-67 S Uncharacterised protein conserved in bacteria (DUF2326)
KOILJNNC_03380 4e-198 yetN S Protein of unknown function (DUF3900)
KOILJNNC_03381 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
KOILJNNC_03382 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOILJNNC_03383 1e-147 rfbF 2.7.7.33 JM Nucleotidyl transferase
KOILJNNC_03384 3.2e-172 yfnG 4.2.1.45 M dehydratase
KOILJNNC_03385 1.1e-180 yfnF M Nucleotide-diphospho-sugar transferase
KOILJNNC_03386 5.5e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
KOILJNNC_03387 1.1e-188 yfnD M Nucleotide-diphospho-sugar transferase
KOILJNNC_03388 1.5e-204 fsr P COG0477 Permeases of the major facilitator superfamily
KOILJNNC_03389 2.5e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
KOILJNNC_03390 1.4e-240 yfnA E amino acid
KOILJNNC_03391 2.4e-278 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KOILJNNC_03392 1.1e-113 yfmS NT chemotaxis protein
KOILJNNC_03393 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KOILJNNC_03394 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
KOILJNNC_03395 2.8e-70 yfmP K transcriptional
KOILJNNC_03396 1.5e-209 yfmO EGP Major facilitator Superfamily
KOILJNNC_03397 7.1e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
KOILJNNC_03398 1.7e-199 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
KOILJNNC_03399 1.9e-32 yfmK 2.3.1.128 K acetyltransferase
KOILJNNC_03400 7.9e-188 yfmJ S N-terminal domain of oxidoreductase
KOILJNNC_03401 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
KOILJNNC_03402 4.7e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03403 4.7e-169 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03404 1.2e-166 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
KOILJNNC_03405 2.6e-24 S Protein of unknown function (DUF3212)
KOILJNNC_03406 7.6e-58 yflT S Heat induced stress protein YflT
KOILJNNC_03407 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
KOILJNNC_03408 2.1e-234 yflS P Sodium:sulfate symporter transmembrane region
KOILJNNC_03409 8.2e-288 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KOILJNNC_03410 1.3e-117 citT T response regulator
KOILJNNC_03411 1.1e-178 yflP S Tripartite tricarboxylate transporter family receptor
KOILJNNC_03412 8.5e-227 citM C Citrate transporter
KOILJNNC_03413 1.3e-150 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
KOILJNNC_03414 7.4e-216 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
KOILJNNC_03415 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
KOILJNNC_03416 5.5e-121 yflK S protein conserved in bacteria
KOILJNNC_03417 4e-18 yflJ S Protein of unknown function (DUF2639)
KOILJNNC_03418 4.1e-19 yflI
KOILJNNC_03419 5.3e-50 yflH S Protein of unknown function (DUF3243)
KOILJNNC_03420 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
KOILJNNC_03421 2e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
KOILJNNC_03422 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
KOILJNNC_03423 3.9e-66 yhdN S Domain of unknown function (DUF1992)
KOILJNNC_03424 2.2e-252 agcS_1 E Sodium alanine symporter
KOILJNNC_03425 2.2e-25 yfkQ EG Spore germination protein
KOILJNNC_03426 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_03427 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
KOILJNNC_03428 1.8e-133 treR K transcriptional
KOILJNNC_03429 1.1e-124 yfkO C nitroreductase
KOILJNNC_03430 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
KOILJNNC_03431 3.6e-88 yfkM 1.11.1.6, 3.5.1.124 S protease
KOILJNNC_03432 1.3e-205 ydiM EGP Major facilitator Superfamily
KOILJNNC_03433 1.3e-28 yfkK S Belongs to the UPF0435 family
KOILJNNC_03434 2.5e-74 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KOILJNNC_03435 3.2e-50 yfkI S gas vesicle protein
KOILJNNC_03436 1.3e-143 yihY S Belongs to the UPF0761 family
KOILJNNC_03437 5e-08
KOILJNNC_03438 3.4e-219 ycaD EGP COG0477 Permeases of the major facilitator superfamily
KOILJNNC_03439 6.1e-183 cax P COG0387 Ca2 H antiporter
KOILJNNC_03440 1.2e-146 yfkD S YfkD-like protein
KOILJNNC_03441 6e-149 yfkC M Mechanosensitive ion channel
KOILJNNC_03442 5.4e-222 yfkA S YfkB-like domain
KOILJNNC_03443 1.1e-26 yfjT
KOILJNNC_03444 1.7e-153 pdaA G deacetylase
KOILJNNC_03445 1.6e-149 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
KOILJNNC_03446 1.7e-184 corA P Mediates influx of magnesium ions
KOILJNNC_03447 8.5e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KOILJNNC_03448 4e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KOILJNNC_03449 2e-43 S YfzA-like protein
KOILJNNC_03450 2.4e-189 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOILJNNC_03451 9.6e-85 yfjM S Psort location Cytoplasmic, score
KOILJNNC_03452 1.7e-29 yfjL
KOILJNNC_03453 3.7e-190 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
KOILJNNC_03454 1.5e-189 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
KOILJNNC_03455 1.9e-193 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
KOILJNNC_03456 2.3e-254 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
KOILJNNC_03457 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
KOILJNNC_03458 1.2e-25 sspH S Belongs to the SspH family
KOILJNNC_03459 3.4e-55 yfjF S UPF0060 membrane protein
KOILJNNC_03460 5.5e-79 S Family of unknown function (DUF5381)
KOILJNNC_03461 3.1e-101 yfjD S Family of unknown function (DUF5381)
KOILJNNC_03462 4.5e-143 yfjC
KOILJNNC_03463 9.2e-191 yfjB
KOILJNNC_03464 4.4e-44 yfjA S Belongs to the WXG100 family
KOILJNNC_03465 5.5e-261 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
KOILJNNC_03466 1e-139 glvR K Helix-turn-helix domain, rpiR family
KOILJNNC_03467 2.3e-295 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_03468 2.4e-306 yfiB3 V ABC transporter
KOILJNNC_03469 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
KOILJNNC_03470 6.4e-64 mhqP S DoxX
KOILJNNC_03471 9.7e-163 yfiE 1.13.11.2 S glyoxalase
KOILJNNC_03473 4.1e-209 yxjM T Histidine kinase
KOILJNNC_03474 1.6e-112 KT LuxR family transcriptional regulator
KOILJNNC_03475 5.4e-167 V ABC transporter, ATP-binding protein
KOILJNNC_03476 2.6e-206 V ABC-2 family transporter protein
KOILJNNC_03477 1.1e-201 V COG0842 ABC-type multidrug transport system, permease component
KOILJNNC_03478 2.4e-98 padR K transcriptional
KOILJNNC_03479 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KOILJNNC_03480 1e-196 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
KOILJNNC_03481 2.1e-99 yfiT S Belongs to the metal hydrolase YfiT family
KOILJNNC_03482 4e-284 yfiU EGP Major facilitator Superfamily
KOILJNNC_03483 4.9e-79 yfiV K transcriptional
KOILJNNC_03484 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KOILJNNC_03485 5.7e-175 yfiY P ABC transporter substrate-binding protein
KOILJNNC_03486 1.5e-175 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03487 1.2e-170 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03488 1.9e-166 yfhB 5.3.3.17 S PhzF family
KOILJNNC_03489 3.9e-107 yfhC C nitroreductase
KOILJNNC_03490 2.1e-25 yfhD S YfhD-like protein
KOILJNNC_03492 9.3e-172 yfhF S nucleoside-diphosphate sugar epimerase
KOILJNNC_03493 1.6e-140 recX 2.4.1.337 GT4 S Modulates RecA activity
KOILJNNC_03494 4.8e-51 yfhH S Protein of unknown function (DUF1811)
KOILJNNC_03496 3.6e-208 yfhI EGP Major facilitator Superfamily
KOILJNNC_03497 6.2e-20 sspK S reproduction
KOILJNNC_03498 1.3e-44 yfhJ S WVELL protein
KOILJNNC_03499 2.1e-88 batE T Bacterial SH3 domain homologues
KOILJNNC_03500 3.9e-50 yfhL S SdpI/YhfL protein family
KOILJNNC_03501 1.3e-170 yfhM S Alpha beta hydrolase
KOILJNNC_03502 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
KOILJNNC_03503 0.0 yfhO S Bacterial membrane protein YfhO
KOILJNNC_03504 1.2e-185 yfhP S membrane-bound metal-dependent
KOILJNNC_03505 3.3e-210 mutY L A G-specific
KOILJNNC_03506 6.9e-36 yfhS
KOILJNNC_03507 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_03508 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
KOILJNNC_03509 1.5e-37 ygaB S YgaB-like protein
KOILJNNC_03510 1.3e-104 ygaC J Belongs to the UPF0374 family
KOILJNNC_03511 1.8e-301 ygaD V ABC transporter
KOILJNNC_03512 3.3e-179 ygaE S Membrane
KOILJNNC_03513 8.9e-245 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
KOILJNNC_03514 8.2e-87 bcp 1.11.1.15 O Peroxiredoxin
KOILJNNC_03515 4e-80 perR P Belongs to the Fur family
KOILJNNC_03516 9.5e-56 ygzB S UPF0295 protein
KOILJNNC_03517 9.7e-166 ygxA S Nucleotidyltransferase-like
KOILJNNC_03518 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
KOILJNNC_03519 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
KOILJNNC_03520 1.7e-139 srfAD Q thioesterase
KOILJNNC_03521 4.4e-225 EGP Major Facilitator Superfamily
KOILJNNC_03522 5.5e-90 S YcxB-like protein
KOILJNNC_03523 9.3e-159 ycxC EG EamA-like transporter family
KOILJNNC_03524 9.5e-250 ycxD K GntR family transcriptional regulator
KOILJNNC_03525 1.9e-113 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
KOILJNNC_03526 2.8e-114 yczE S membrane
KOILJNNC_03527 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
KOILJNNC_03528 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
KOILJNNC_03529 6.4e-140 tcyA ET Belongs to the bacterial solute-binding protein 3 family
KOILJNNC_03530 6.4e-162 bsdA K LysR substrate binding domain
KOILJNNC_03531 1.1e-107 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
KOILJNNC_03532 2.2e-281 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
KOILJNNC_03533 4e-39 bsdD 4.1.1.61 S response to toxic substance
KOILJNNC_03534 7.3e-80 yclD
KOILJNNC_03535 1.9e-158 yclE 3.4.11.5 S Alpha beta hydrolase
KOILJNNC_03536 1.8e-265 dtpT E amino acid peptide transporter
KOILJNNC_03537 4.1e-309 yclG M Pectate lyase superfamily protein
KOILJNNC_03539 1.7e-277 gerKA EG Spore germination protein
KOILJNNC_03540 1.2e-230 gerKC S spore germination
KOILJNNC_03541 3.8e-199 gerKB F Spore germination protein
KOILJNNC_03542 5.6e-121 yclH P ABC transporter
KOILJNNC_03543 9e-201 yclI V ABC transporter (permease) YclI
KOILJNNC_03544 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_03545 1.1e-259 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
KOILJNNC_03546 1.3e-77 S aspartate phosphatase
KOILJNNC_03550 1.2e-250 lysC 2.7.2.4 E Belongs to the aspartokinase family
KOILJNNC_03551 3.5e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03552 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03553 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
KOILJNNC_03554 6.1e-166 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
KOILJNNC_03555 1e-249 ycnB EGP Major facilitator Superfamily
KOILJNNC_03556 6.5e-154 ycnC K Transcriptional regulator
KOILJNNC_03557 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
KOILJNNC_03558 1.6e-45 ycnE S Monooxygenase
KOILJNNC_03559 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
KOILJNNC_03560 3.6e-271 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_03561 1.2e-244 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KOILJNNC_03562 1.3e-265 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KOILJNNC_03563 6.1e-149 glcU U Glucose uptake
KOILJNNC_03564 6e-143 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_03565 1.4e-99 ycnI S protein conserved in bacteria
KOILJNNC_03566 1.6e-307 ycnJ P protein, homolog of Cu resistance protein CopC
KOILJNNC_03567 1.8e-104 ycnK K COG1349 Transcriptional regulators of sugar metabolism
KOILJNNC_03568 3.4e-53
KOILJNNC_03569 7.4e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
KOILJNNC_03570 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
KOILJNNC_03571 1.4e-209 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
KOILJNNC_03572 1.9e-200 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
KOILJNNC_03573 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KOILJNNC_03574 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
KOILJNNC_03575 4e-107 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
KOILJNNC_03576 1.6e-67 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
KOILJNNC_03578 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
KOILJNNC_03579 1e-139 ycsF S Belongs to the UPF0271 (lamB) family
KOILJNNC_03580 3.9e-210 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
KOILJNNC_03581 5.3e-147 ycsI S Belongs to the D-glutamate cyclase family
KOILJNNC_03582 3e-133 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
KOILJNNC_03583 3.6e-185 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
KOILJNNC_03584 1e-131 kipR K Transcriptional regulator
KOILJNNC_03585 3.5e-117 ycsK E anatomical structure formation involved in morphogenesis
KOILJNNC_03587 8e-47 yczJ S biosynthesis
KOILJNNC_03588 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
KOILJNNC_03589 4e-175 ydhF S Oxidoreductase
KOILJNNC_03590 0.0 mtlR K transcriptional regulator, MtlR
KOILJNNC_03591 2.7e-293 ydaB IQ acyl-CoA ligase
KOILJNNC_03592 4.9e-97 ydaC Q Methyltransferase domain
KOILJNNC_03593 4.1e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
KOILJNNC_03594 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
KOILJNNC_03595 3e-101 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
KOILJNNC_03596 6.8e-77 ydaG 1.4.3.5 S general stress protein
KOILJNNC_03597 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
KOILJNNC_03598 3.6e-45 ydzA EGP Major facilitator Superfamily
KOILJNNC_03599 2.5e-74 lrpC K Transcriptional regulator
KOILJNNC_03600 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KOILJNNC_03601 1.1e-206 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
KOILJNNC_03602 1.3e-151 ydaK T Diguanylate cyclase, GGDEF domain
KOILJNNC_03603 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
KOILJNNC_03604 3.8e-232 ydaM M Glycosyl transferase family group 2
KOILJNNC_03605 0.0 ydaN S Bacterial cellulose synthase subunit
KOILJNNC_03606 0.0 ydaO E amino acid
KOILJNNC_03607 3.6e-76 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
KOILJNNC_03608 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
KOILJNNC_03609 1.1e-37
KOILJNNC_03610 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
KOILJNNC_03612 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
KOILJNNC_03613 7.9e-146 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
KOILJNNC_03615 8.9e-59 ydbB G Cupin domain
KOILJNNC_03616 3.1e-62 ydbC S Domain of unknown function (DUF4937
KOILJNNC_03617 2.3e-153 ydbD P Catalase
KOILJNNC_03618 1.1e-197 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
KOILJNNC_03619 2.8e-296 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
KOILJNNC_03620 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
KOILJNNC_03621 1.4e-226 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOILJNNC_03622 4.4e-181 ydbI S AI-2E family transporter
KOILJNNC_03623 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
KOILJNNC_03624 9.4e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
KOILJNNC_03625 2.7e-52 ydbL
KOILJNNC_03626 9.8e-219 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
KOILJNNC_03627 1.1e-18 S Fur-regulated basic protein B
KOILJNNC_03628 2.2e-07 S Fur-regulated basic protein A
KOILJNNC_03629 2.5e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOILJNNC_03630 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
KOILJNNC_03631 1.1e-200 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
KOILJNNC_03632 8.6e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
KOILJNNC_03633 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
KOILJNNC_03634 2.1e-82 ydbS S Bacterial PH domain
KOILJNNC_03635 5.1e-260 ydbT S Membrane
KOILJNNC_03636 2.4e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
KOILJNNC_03637 8.9e-57 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
KOILJNNC_03638 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
KOILJNNC_03639 1.9e-222 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KOILJNNC_03640 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
KOILJNNC_03641 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
KOILJNNC_03642 1.3e-143 rsbR T Positive regulator of sigma-B
KOILJNNC_03643 5.2e-57 rsbS T antagonist
KOILJNNC_03644 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
KOILJNNC_03645 7.1e-189 rsbU 3.1.3.3 KT phosphatase
KOILJNNC_03646 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
KOILJNNC_03647 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
KOILJNNC_03648 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KOILJNNC_03649 1.1e-107 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
KOILJNNC_03650 0.0 yhgF K COG2183 Transcriptional accessory protein
KOILJNNC_03651 8.9e-83 ydcK S Belongs to the SprT family
KOILJNNC_03659 3.2e-138 yddH CBM50 M Lysozyme-like
KOILJNNC_03660 2.2e-89 K Helix-turn-helix XRE-family like proteins
KOILJNNC_03661 4.1e-84 yddI
KOILJNNC_03662 5.1e-63 S Domain of unknown function with cystatin-like fold (DUF4467)
KOILJNNC_03663 1.7e-64 S response regulator aspartate phosphatase
KOILJNNC_03665 2.2e-294 L Excinuclease ATPase subunit
KOILJNNC_03666 6.2e-44 K transcriptional regulator
KOILJNNC_03667 5.2e-29 sugE P Multidrug Resistance protein
KOILJNNC_03668 1.1e-32 sugE P Multidrug resistance protein
KOILJNNC_03669 2.7e-147 EGP Major facilitator Superfamily
KOILJNNC_03670 2.3e-77 K TetR family transcriptional regulator
KOILJNNC_03671 2.1e-47 S DoxX-like family
KOILJNNC_03672 1.1e-117 S Belongs to the pirin family
KOILJNNC_03673 7.4e-53 K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_03674 1.6e-15 S auxin efflux carrier
KOILJNNC_03675 2.2e-28
KOILJNNC_03676 5.6e-137 rhaS9 K AraC-like ligand binding domain
KOILJNNC_03677 1.9e-59 yyaQ S YjbR
KOILJNNC_03678 3.2e-120 dapA_5 4.3.3.7 EM Dihydrodipicolinate synthetase family
KOILJNNC_03679 7.1e-154 yeaN P transporter
KOILJNNC_03680 1.3e-133 cynR K Transcriptional regulator
KOILJNNC_03681 6.4e-87 S protein conserved in bacteria
KOILJNNC_03682 1e-17 MA20_06410 E threonine efflux protein
KOILJNNC_03683 1.2e-33 K Helix-turn-helix XRE-family like proteins
KOILJNNC_03684 2.8e-39
KOILJNNC_03685 1.6e-191 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
KOILJNNC_03686 8.7e-30 cspL K Cold shock
KOILJNNC_03687 2.3e-78 carD K Transcription factor
KOILJNNC_03688 1.5e-139 ydzE EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOILJNNC_03689 5.4e-161 rhaS5 K AraC-like ligand binding domain
KOILJNNC_03690 1.4e-170 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
KOILJNNC_03691 5.3e-164 ydeE K AraC family transcriptional regulator
KOILJNNC_03692 1.2e-260 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_03693 3.5e-217 ydeG EGP Major facilitator superfamily
KOILJNNC_03694 2.7e-45 ydeH
KOILJNNC_03695 6.4e-105 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
KOILJNNC_03696 5.4e-100
KOILJNNC_03697 5.8e-77 ksgA1 I Ribosomal RNA adenine dimethylase
KOILJNNC_03698 2.5e-113 T Transcriptional regulator
KOILJNNC_03699 3.8e-140 T PhoQ Sensor
KOILJNNC_03700 8.4e-71 S SNARE associated Golgi protein
KOILJNNC_03701 3.7e-15 ptsH G PTS HPr component phosphorylation site
KOILJNNC_03702 8.8e-85 K Transcriptional regulator C-terminal region
KOILJNNC_03703 1.8e-153 ydeK EG -transporter
KOILJNNC_03704 1.1e-272 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_03705 6e-73 maoC I N-terminal half of MaoC dehydratase
KOILJNNC_03706 1.8e-104 ydeN S Serine hydrolase
KOILJNNC_03707 8.9e-56 K HxlR-like helix-turn-helix
KOILJNNC_03708 2.3e-151 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
KOILJNNC_03709 4.8e-69 ydeP K Transcriptional regulator
KOILJNNC_03710 7.9e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
KOILJNNC_03711 1.1e-193 ydeR EGP Major facilitator Superfamily
KOILJNNC_03712 3.2e-104 ydeS K Transcriptional regulator
KOILJNNC_03713 6.3e-57 arsR K transcriptional
KOILJNNC_03714 1.4e-229 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KOILJNNC_03715 1.1e-144 ydfB J GNAT acetyltransferase
KOILJNNC_03716 2.8e-149 lytR K Transcriptional regulator
KOILJNNC_03717 1e-121 nodB1 G deacetylase
KOILJNNC_03718 1.5e-158
KOILJNNC_03719 3.3e-211 T GHKL domain
KOILJNNC_03720 6.8e-123 T Transcriptional regulatory protein, C terminal
KOILJNNC_03721 2.2e-149 ydfC EG EamA-like transporter family
KOILJNNC_03722 5.6e-272 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
KOILJNNC_03723 4.2e-115 ydfE S Flavin reductase like domain
KOILJNNC_03724 4.6e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
KOILJNNC_03725 1.7e-78 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KOILJNNC_03727 6.1e-176 ydfH 2.7.13.3 T Histidine kinase
KOILJNNC_03728 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
KOILJNNC_03729 0.0 ydfJ S drug exporters of the RND superfamily
KOILJNNC_03730 9.8e-174 S Alpha/beta hydrolase family
KOILJNNC_03731 1.9e-116 S Protein of unknown function (DUF554)
KOILJNNC_03732 6.6e-145 K Bacterial transcription activator, effector binding domain
KOILJNNC_03733 6.6e-154 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KOILJNNC_03734 9.6e-112 ydfN C nitroreductase
KOILJNNC_03735 2e-185 ydfO E COG0346 Lactoylglutathione lyase and related lyases
KOILJNNC_03736 8.8e-63 mhqP S DoxX
KOILJNNC_03737 1e-54 traF CO Thioredoxin
KOILJNNC_03738 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
KOILJNNC_03739 6.3e-29
KOILJNNC_03741 1.9e-99 ydfR S Protein of unknown function (DUF421)
KOILJNNC_03742 2.6e-121 ydfS S Protein of unknown function (DUF421)
KOILJNNC_03743 3.2e-74 cotP O Belongs to the small heat shock protein (HSP20) family
KOILJNNC_03744 2.3e-37 ydgA S Spore germination protein gerPA/gerPF
KOILJNNC_03745 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
KOILJNNC_03746 5.3e-99 K Bacterial regulatory proteins, tetR family
KOILJNNC_03747 2.4e-51 S DoxX-like family
KOILJNNC_03748 1.6e-82 yycN 2.3.1.128 K Acetyltransferase
KOILJNNC_03749 5.4e-303 expZ S ABC transporter
KOILJNNC_03750 5.2e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_03751 1.2e-86 dinB S DinB family
KOILJNNC_03752 6e-79 K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_03753 0.0 ydgH S drug exporters of the RND superfamily
KOILJNNC_03754 1e-113 drgA C nitroreductase
KOILJNNC_03755 2.4e-69 ydgJ K Winged helix DNA-binding domain
KOILJNNC_03756 2.2e-208 tcaB EGP Major facilitator Superfamily
KOILJNNC_03757 3.5e-121 ydhB S membrane transporter protein
KOILJNNC_03758 3e-119 ydhC K FCD
KOILJNNC_03759 1.1e-242 ydhD M Glycosyl hydrolase
KOILJNNC_03760 1.2e-227 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
KOILJNNC_03761 3.3e-124
KOILJNNC_03762 5.2e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
KOILJNNC_03763 3e-68 frataxin S Domain of unknown function (DU1801)
KOILJNNC_03765 7.5e-80 K Acetyltransferase (GNAT) domain
KOILJNNC_03766 6.9e-181 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
KOILJNNC_03767 9.4e-98 ydhK M Protein of unknown function (DUF1541)
KOILJNNC_03768 1e-199 pbuE EGP Major facilitator Superfamily
KOILJNNC_03769 1.2e-46 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
KOILJNNC_03770 5.6e-50 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
KOILJNNC_03771 1.7e-238 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
KOILJNNC_03772 1.2e-282 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOILJNNC_03773 3.1e-130 ydhQ K UTRA
KOILJNNC_03774 5.8e-166 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
KOILJNNC_03775 2e-185 manA 5.3.1.8 G mannose-6-phosphate isomerase
KOILJNNC_03776 1.3e-212 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
KOILJNNC_03777 1e-156 ydhU P Catalase
KOILJNNC_03780 1.3e-63 hxlR K transcriptional
KOILJNNC_03781 4.7e-106 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
KOILJNNC_03782 1.1e-95 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
KOILJNNC_03783 6.2e-185 tlpC 2.7.13.3 NT chemotaxis protein
KOILJNNC_03784 7.8e-71 nucA M Deoxyribonuclease NucA/NucB
KOILJNNC_03785 1.1e-68 nin S Competence protein J (ComJ)
KOILJNNC_03786 5.7e-293 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
KOILJNNC_03787 7.8e-52 yckD S Protein of unknown function (DUF2680)
KOILJNNC_03788 3.1e-75 yckC S membrane
KOILJNNC_03790 1.7e-130 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
KOILJNNC_03791 5.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
KOILJNNC_03792 5e-226 yciC S GTPases (G3E family)
KOILJNNC_03794 4.4e-100 yciB M ErfK YbiS YcfS YnhG
KOILJNNC_03795 1.3e-170 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
KOILJNNC_03796 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
KOILJNNC_03797 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
KOILJNNC_03798 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KOILJNNC_03799 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KOILJNNC_03800 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
KOILJNNC_03801 6e-274 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
KOILJNNC_03802 9.3e-189 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
KOILJNNC_03803 5.9e-160 I alpha/beta hydrolase fold
KOILJNNC_03804 6.5e-138 ycgR S permeases
KOILJNNC_03805 2.2e-146 ycgQ S membrane
KOILJNNC_03806 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
KOILJNNC_03807 2e-261 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KOILJNNC_03808 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
KOILJNNC_03809 5.1e-170 ycgM E Proline dehydrogenase
KOILJNNC_03810 4.1e-144 ycgL S Predicted nucleotidyltransferase
KOILJNNC_03811 3.6e-182 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
KOILJNNC_03812 2.7e-177 oxyR3 K LysR substrate binding domain
KOILJNNC_03813 9e-144 yafE Q ubiE/COQ5 methyltransferase family
KOILJNNC_03814 1.5e-103 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KOILJNNC_03816 3.1e-107 tmrB S AAA domain
KOILJNNC_03817 7.6e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
KOILJNNC_03818 9.3e-112 ycgI S Domain of unknown function (DUF1989)
KOILJNNC_03819 4.8e-249 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_03820 2.2e-150 yqcI S YqcI/YcgG family
KOILJNNC_03821 6.8e-113 ycgF E Lysine exporter protein LysE YggA
KOILJNNC_03822 2.9e-76 emrR K helix_turn_helix multiple antibiotic resistance protein
KOILJNNC_03823 3.3e-262 mdr EGP Major facilitator Superfamily
KOILJNNC_03824 4.7e-291 lctP C L-lactate permease
KOILJNNC_03825 4.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
KOILJNNC_03826 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
KOILJNNC_03827 4.5e-80 ycgB
KOILJNNC_03828 5.6e-256 ycgA S Membrane
KOILJNNC_03829 8.6e-215 amhX S amidohydrolase
KOILJNNC_03830 5.3e-164 opuAC E glycine betaine
KOILJNNC_03831 1.3e-127 opuAB P glycine betaine
KOILJNNC_03832 2.5e-228 proV 3.6.3.32 E glycine betaine
KOILJNNC_03833 6.1e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
KOILJNNC_03834 5.9e-203 yceJ EGP Uncharacterised MFS-type transporter YbfB
KOILJNNC_03835 1.5e-217 naiP P Uncharacterised MFS-type transporter YbfB
KOILJNNC_03836 2e-192 yceH P Belongs to the TelA family
KOILJNNC_03837 0.0 yceG S Putative component of 'biosynthetic module'
KOILJNNC_03838 6.3e-137 terC P Protein of unknown function (DUF475)
KOILJNNC_03839 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
KOILJNNC_03840 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
KOILJNNC_03841 1.5e-109 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
KOILJNNC_03842 1.4e-184 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KOILJNNC_03843 6.4e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
KOILJNNC_03844 9.4e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
KOILJNNC_03845 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
KOILJNNC_03846 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
KOILJNNC_03847 6.8e-139 IQ Enoyl-(Acyl carrier protein) reductase
KOILJNNC_03848 2.1e-173 S response regulator aspartate phosphatase
KOILJNNC_03849 1.3e-93 cwlK M D-alanyl-D-alanine carboxypeptidase
KOILJNNC_03850 4.5e-256 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_03851 7.3e-272 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_03852 6.6e-177 ycdA S Domain of unknown function (DUF5105)
KOILJNNC_03853 1.7e-173 yccK C Aldo keto reductase
KOILJNNC_03854 3.3e-198 natB CP ABC-2 family transporter protein
KOILJNNC_03855 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
KOILJNNC_03856 1.2e-126 lytR_2 T LytTr DNA-binding domain
KOILJNNC_03857 3e-152 2.7.13.3 T GHKL domain
KOILJNNC_03858 2.8e-199 yccF K DNA-templated transcriptional preinitiation complex assembly
KOILJNNC_03859 7.6e-59 S RDD family
KOILJNNC_03860 9.3e-102 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
KOILJNNC_03861 2e-200 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
KOILJNNC_03862 5.9e-100 yxaF K Transcriptional regulator
KOILJNNC_03863 7.6e-229 lmrB EGP the major facilitator superfamily
KOILJNNC_03864 1.1e-203 ycbU E Selenocysteine lyase
KOILJNNC_03865 2.5e-118 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KOILJNNC_03866 2.6e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KOILJNNC_03867 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
KOILJNNC_03868 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
KOILJNNC_03869 4.9e-44 ycbR T vWA found in TerF C terminus
KOILJNNC_03870 1e-63 ycbR T vWA found in TerF C terminus
KOILJNNC_03871 2.2e-78 sleB 3.5.1.28 M Cell wall
KOILJNNC_03872 4.1e-52 ycbP S Protein of unknown function (DUF2512)
KOILJNNC_03873 3.3e-113 S ABC-2 family transporter protein
KOILJNNC_03874 5.9e-166 ycbN V ABC transporter, ATP-binding protein
KOILJNNC_03875 1.9e-167 T PhoQ Sensor
KOILJNNC_03876 1.9e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
KOILJNNC_03877 1.5e-169 eamA1 EG spore germination
KOILJNNC_03878 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
KOILJNNC_03879 1.7e-173 ycbJ S Macrolide 2'-phosphotransferase
KOILJNNC_03880 2e-296 garD 4.2.1.42, 4.2.1.7 G Altronate
KOILJNNC_03881 2.1e-123 ycbG K FCD
KOILJNNC_03882 1.5e-269 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
KOILJNNC_03883 2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
KOILJNNC_03884 3.4e-272 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
KOILJNNC_03885 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
KOILJNNC_03886 2e-169 glnL T Regulator
KOILJNNC_03887 4.2e-229 phoQ 2.7.13.3 T Histidine kinase
KOILJNNC_03888 2.9e-187 glsA 3.5.1.2 E Belongs to the glutaminase family
KOILJNNC_03889 4.8e-255 agcS E Sodium alanine symporter
KOILJNNC_03890 1.1e-180 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
KOILJNNC_03891 6.3e-260 mmuP E amino acid
KOILJNNC_03892 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
KOILJNNC_03894 8.4e-128 K UTRA
KOILJNNC_03895 2e-135 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
KOILJNNC_03896 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_03897 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
KOILJNNC_03898 1.9e-191 yceA S Belongs to the UPF0176 family
KOILJNNC_03899 2.1e-252 S Erythromycin esterase
KOILJNNC_03900 4.6e-45 ybfN
KOILJNNC_03901 8.1e-148 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
KOILJNNC_03902 2.7e-85 ybfM S SNARE associated Golgi protein
KOILJNNC_03903 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KOILJNNC_03904 6.3e-165 S Alpha/beta hydrolase family
KOILJNNC_03906 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
KOILJNNC_03907 3.6e-213 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KOILJNNC_03908 5.7e-144 msmR K AraC-like ligand binding domain
KOILJNNC_03909 1.1e-159 ybfH EG EamA-like transporter family
KOILJNNC_03910 3.3e-220 ybfB G COG0477 Permeases of the major facilitator superfamily
KOILJNNC_03911 2.2e-168 ybfA 3.4.15.5 K FR47-like protein
KOILJNNC_03912 1.5e-34 S Protein of unknown function (DUF2651)
KOILJNNC_03913 7.3e-258 glpT G -transporter
KOILJNNC_03914 7.6e-163 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
KOILJNNC_03915 1.2e-289 ybeC E amino acid
KOILJNNC_03916 4.9e-41 ybyB
KOILJNNC_03917 2.5e-244 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
KOILJNNC_03918 7.5e-149 ybxI 3.5.2.6 V beta-lactamase
KOILJNNC_03919 4.9e-30 ybxH S Family of unknown function (DUF5370)
KOILJNNC_03920 1.1e-37 csgA S Sigma-G-dependent sporulation-specific SASP protein
KOILJNNC_03921 1.5e-258 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
KOILJNNC_03922 9.8e-214 ybdO S Domain of unknown function (DUF4885)
KOILJNNC_03923 1.2e-152 ybdN
KOILJNNC_03924 1.8e-139 KLT Protein tyrosine kinase
KOILJNNC_03926 5e-171 T His Kinase A (phospho-acceptor) domain
KOILJNNC_03927 1.3e-122 T Transcriptional regulatory protein, C terminal
KOILJNNC_03928 1.3e-179 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
KOILJNNC_03929 9.6e-79 txn CO Thioredoxin-like
KOILJNNC_03930 7.8e-91 C HEAT repeats
KOILJNNC_03931 2e-247 skfF S ABC transporter
KOILJNNC_03932 6.7e-133 skfE V ABC transporter
KOILJNNC_03933 2.8e-274 V CAAX protease self-immunity
KOILJNNC_03934 9.1e-239 J 4Fe-4S single cluster domain
KOILJNNC_03936 4.2e-201 ybcL EGP Major facilitator Superfamily
KOILJNNC_03937 5.1e-50 ybzH K Helix-turn-helix domain
KOILJNNC_03938 3.2e-59 ybcI S Uncharacterized conserved protein (DUF2294)
KOILJNNC_03939 8.7e-47
KOILJNNC_03941 4e-90 can 4.2.1.1 P carbonic anhydrase
KOILJNNC_03942 0.0 ybcC S Belongs to the UPF0753 family
KOILJNNC_03943 7e-273 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
KOILJNNC_03944 4.8e-99 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KOILJNNC_03945 6.4e-119 adaA 3.2.2.21 K Transcriptional regulator
KOILJNNC_03946 5.3e-175 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KOILJNNC_03947 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
KOILJNNC_03948 7.9e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KOILJNNC_03949 3e-225 ybbR S protein conserved in bacteria
KOILJNNC_03950 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KOILJNNC_03951 6.3e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
KOILJNNC_03952 2.5e-98 sigW K Belongs to the sigma-70 factor family. ECF subfamily
KOILJNNC_03958 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
KOILJNNC_03959 1.9e-86 ybbJ J acetyltransferase
KOILJNNC_03960 6.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KOILJNNC_03961 1.4e-150 ybbH K transcriptional
KOILJNNC_03962 1.1e-232 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
KOILJNNC_03963 5.4e-253 yfeW 3.4.16.4 V Belongs to the UPF0214 family
KOILJNNC_03964 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
KOILJNNC_03965 2.7e-238 ybbC 3.2.1.52 S protein conserved in bacteria
KOILJNNC_03966 4.7e-304 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
KOILJNNC_03967 1.6e-153 feuA P Iron-uptake system-binding protein
KOILJNNC_03968 3.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03969 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KOILJNNC_03970 1.4e-141 ybbA S Putative esterase
KOILJNNC_03971 1.3e-160 ybaS 1.1.1.58 S Na -dependent transporter
KOILJNNC_03973 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
KOILJNNC_03975 4.6e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
KOILJNNC_03976 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
KOILJNNC_03977 1.2e-84 gerD
KOILJNNC_03978 5.1e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
KOILJNNC_03979 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
KOILJNNC_03980 9.7e-66 ybaK S Protein of unknown function (DUF2521)
KOILJNNC_03981 2e-143 ybaJ Q Methyltransferase domain
KOILJNNC_03982 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
KOILJNNC_03983 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KOILJNNC_03984 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
KOILJNNC_03985 1e-118 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOILJNNC_03986 3.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOILJNNC_03987 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KOILJNNC_03988 3.6e-58 rplQ J Ribosomal protein L17
KOILJNNC_03989 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOILJNNC_03990 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KOILJNNC_03991 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KOILJNNC_03992 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
KOILJNNC_03993 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KOILJNNC_03994 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
KOILJNNC_03995 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
KOILJNNC_03996 5.5e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
KOILJNNC_03997 1.8e-72 rplO J binds to the 23S rRNA
KOILJNNC_03998 1.9e-23 rpmD J Ribosomal protein L30
KOILJNNC_03999 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KOILJNNC_04000 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KOILJNNC_04001 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KOILJNNC_04002 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KOILJNNC_04003 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KOILJNNC_04004 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KOILJNNC_04005 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KOILJNNC_04006 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KOILJNNC_04007 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KOILJNNC_04008 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
KOILJNNC_04009 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KOILJNNC_04010 8e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KOILJNNC_04011 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KOILJNNC_04012 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KOILJNNC_04013 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KOILJNNC_04014 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
KOILJNNC_04015 3e-105 rplD J Forms part of the polypeptide exit tunnel
KOILJNNC_04016 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KOILJNNC_04017 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
KOILJNNC_04018 6.5e-184 ybaC 3.4.11.5 S Alpha/beta hydrolase family
KOILJNNC_04019 8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KOILJNNC_04020 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KOILJNNC_04021 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
KOILJNNC_04022 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KOILJNNC_04023 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
KOILJNNC_04024 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOILJNNC_04025 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KOILJNNC_04026 1.1e-107 rsmC 2.1.1.172 J Methyltransferase
KOILJNNC_04027 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
KOILJNNC_04028 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KOILJNNC_04029 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
KOILJNNC_04030 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KOILJNNC_04031 5.2e-96 nusG K Participates in transcription elongation, termination and antitermination
KOILJNNC_04032 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
KOILJNNC_04033 4.4e-115 sigH K Belongs to the sigma-70 factor family
KOILJNNC_04034 1.2e-88 yacP S RNA-binding protein containing a PIN domain
KOILJNNC_04035 2.6e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KOILJNNC_04036 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
KOILJNNC_04037 2.1e-271 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
KOILJNNC_04038 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
KOILJNNC_04039 2.5e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KOILJNNC_04040 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
KOILJNNC_04041 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
KOILJNNC_04042 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
KOILJNNC_04043 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
KOILJNNC_04044 6.2e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KOILJNNC_04045 0.0 clpC O Belongs to the ClpA ClpB family
KOILJNNC_04046 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
KOILJNNC_04047 2.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
KOILJNNC_04048 2.9e-76 ctsR K Belongs to the CtsR family
KOILJNNC_04049 3.8e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
KOILJNNC_04050 8.3e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KOILJNNC_04051 4.1e-30 yazB K transcriptional
KOILJNNC_04052 3e-87 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KOILJNNC_04053 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KOILJNNC_04054 5.9e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KOILJNNC_04055 7.4e-166 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
KOILJNNC_04056 9.6e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
KOILJNNC_04057 1.7e-268 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KOILJNNC_04058 2.6e-169 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
KOILJNNC_04059 4.4e-135 yacD 5.2.1.8 O peptidyl-prolyl isomerase
KOILJNNC_04060 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KOILJNNC_04061 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KOILJNNC_04062 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KOILJNNC_04063 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
KOILJNNC_04064 1.9e-272 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
KOILJNNC_04065 3.1e-184 KLT serine threonine protein kinase
KOILJNNC_04066 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
KOILJNNC_04067 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
KOILJNNC_04070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
KOILJNNC_04071 1.1e-44 divIC D Septum formation initiator
KOILJNNC_04072 9.5e-107 yabQ S spore cortex biosynthesis protein
KOILJNNC_04073 1.5e-49 yabP S Sporulation protein YabP
KOILJNNC_04074 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
KOILJNNC_04075 1.1e-243 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
KOILJNNC_04076 9.3e-284 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
KOILJNNC_04077 1.5e-92 spoVT K stage V sporulation protein
KOILJNNC_04078 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KOILJNNC_04079 2.4e-39 yabK S Peptide ABC transporter permease
KOILJNNC_04080 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
KOILJNNC_04081 3.6e-95 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KOILJNNC_04082 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KOILJNNC_04083 1.9e-229 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KOILJNNC_04084 4.6e-48 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
KOILJNNC_04085 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
KOILJNNC_04086 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
KOILJNNC_04087 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KOILJNNC_04088 7.8e-39 veg S protein conserved in bacteria
KOILJNNC_04089 1.8e-135 yabG S peptidase
KOILJNNC_04090 1.5e-155 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
KOILJNNC_04091 3.5e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
KOILJNNC_04092 2e-167 rpfB GH23 T protein conserved in bacteria
KOILJNNC_04093 1.2e-143 tatD L hydrolase, TatD
KOILJNNC_04094 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KOILJNNC_04095 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
KOILJNNC_04096 1.2e-152 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KOILJNNC_04097 1.5e-49 yazA L endonuclease containing a URI domain
KOILJNNC_04098 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
KOILJNNC_04099 4.8e-31 yabA L Involved in initiation control of chromosome replication
KOILJNNC_04100 6.1e-146 yaaT S stage 0 sporulation protein
KOILJNNC_04101 2.2e-182 holB 2.7.7.7 L DNA polymerase III
KOILJNNC_04102 4.5e-71 yaaR S protein conserved in bacteria
KOILJNNC_04103 2.2e-54 yaaQ S protein conserved in bacteria
KOILJNNC_04104 6.9e-113 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KOILJNNC_04105 2.5e-272 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
KOILJNNC_04106 2.2e-202 yaaN P Belongs to the TelA family
KOILJNNC_04107 7.6e-101 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
KOILJNNC_04108 3.4e-31 csfB S Inhibitor of sigma-G Gin
KOILJNNC_04109 2.5e-180 yaaC S YaaC-like Protein
KOILJNNC_04110 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
KOILJNNC_04111 1.2e-247 dacA 3.4.16.4 M Belongs to the peptidase S11 family
KOILJNNC_04112 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KOILJNNC_04113 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KOILJNNC_04114 2.4e-205 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KOILJNNC_04115 1.3e-09
KOILJNNC_04116 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
KOILJNNC_04117 3.6e-114 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
KOILJNNC_04118 6.2e-214 yaaH M Glycoside Hydrolase Family
KOILJNNC_04119 5e-96 yaaI Q COG1335 Amidases related to nicotinamidase
KOILJNNC_04120 1.1e-83 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
KOILJNNC_04121 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KOILJNNC_04122 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KOILJNNC_04123 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KOILJNNC_04124 7.9e-32 yaaL S Protein of unknown function (DUF2508)
KOILJNNC_04125 8.2e-36 bofA S Sigma-K factor-processing regulatory protein BofA

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)