ORF_ID e_value Gene_name EC_number CAZy COGs Description
MHPHHPDM_00001 7.5e-49 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_00002 1.2e-14 K Bacterial regulatory proteins, tetR family
MHPHHPDM_00003 4.7e-214 S membrane
MHPHHPDM_00004 9.2e-82 K Bacterial regulatory proteins, tetR family
MHPHHPDM_00005 0.0 CP_1020 S Zinc finger, swim domain protein
MHPHHPDM_00006 2e-112 GM epimerase
MHPHHPDM_00007 4.1e-68 S Protein of unknown function (DUF1722)
MHPHHPDM_00008 9.1e-71 yneH 1.20.4.1 P ArsC family
MHPHHPDM_00009 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
MHPHHPDM_00010 8e-137 K DeoR C terminal sensor domain
MHPHHPDM_00011 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHPHHPDM_00012 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MHPHHPDM_00013 4.3e-77 K Transcriptional regulator
MHPHHPDM_00014 2.2e-241 EGP Major facilitator Superfamily
MHPHHPDM_00015 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHPHHPDM_00016 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
MHPHHPDM_00017 2.2e-179 C Zinc-binding dehydrogenase
MHPHHPDM_00018 1.5e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
MHPHHPDM_00019 1.7e-207
MHPHHPDM_00020 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_00021 7.8e-61 P Rhodanese Homology Domain
MHPHHPDM_00022 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MHPHHPDM_00023 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_00024 3.2e-167 drrA V ABC transporter
MHPHHPDM_00025 2e-119 drrB U ABC-2 type transporter
MHPHHPDM_00026 6.9e-223 M O-Antigen ligase
MHPHHPDM_00027 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
MHPHHPDM_00028 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MHPHHPDM_00029 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MHPHHPDM_00030 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHPHHPDM_00032 5.6e-29 S Protein of unknown function (DUF2929)
MHPHHPDM_00033 0.0 dnaE 2.7.7.7 L DNA polymerase
MHPHHPDM_00034 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MHPHHPDM_00035 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MHPHHPDM_00036 1.5e-74 yeaL S Protein of unknown function (DUF441)
MHPHHPDM_00037 1.1e-169 cvfB S S1 domain
MHPHHPDM_00038 1.1e-164 xerD D recombinase XerD
MHPHHPDM_00039 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MHPHHPDM_00040 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MHPHHPDM_00041 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MHPHHPDM_00042 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHPHHPDM_00043 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MHPHHPDM_00044 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
MHPHHPDM_00045 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MHPHHPDM_00046 2e-19 M Lysin motif
MHPHHPDM_00047 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MHPHHPDM_00048 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
MHPHHPDM_00049 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MHPHHPDM_00050 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MHPHHPDM_00051 2.1e-206 S Tetratricopeptide repeat protein
MHPHHPDM_00052 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
MHPHHPDM_00053 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MHPHHPDM_00054 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MHPHHPDM_00055 9.6e-85
MHPHHPDM_00056 0.0 yfmR S ABC transporter, ATP-binding protein
MHPHHPDM_00057 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MHPHHPDM_00058 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MHPHHPDM_00059 5.1e-148 DegV S EDD domain protein, DegV family
MHPHHPDM_00060 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
MHPHHPDM_00061 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MHPHHPDM_00062 3.4e-35 yozE S Belongs to the UPF0346 family
MHPHHPDM_00063 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MHPHHPDM_00064 7.3e-251 emrY EGP Major facilitator Superfamily
MHPHHPDM_00065 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
MHPHHPDM_00066 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MHPHHPDM_00067 2.3e-173 L restriction endonuclease
MHPHHPDM_00068 3.1e-170 cpsY K Transcriptional regulator, LysR family
MHPHHPDM_00069 6.8e-228 XK27_05470 E Methionine synthase
MHPHHPDM_00071 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MHPHHPDM_00072 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPHHPDM_00073 9.5e-158 dprA LU DNA protecting protein DprA
MHPHHPDM_00074 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MHPHHPDM_00075 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MHPHHPDM_00076 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MHPHHPDM_00077 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MHPHHPDM_00078 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MHPHHPDM_00079 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
MHPHHPDM_00080 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MHPHHPDM_00081 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPHHPDM_00082 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MHPHHPDM_00083 5.9e-177 K Transcriptional regulator
MHPHHPDM_00084 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
MHPHHPDM_00085 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MHPHHPDM_00086 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHPHHPDM_00087 4.2e-32 S YozE SAM-like fold
MHPHHPDM_00088 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
MHPHHPDM_00089 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPHHPDM_00090 6.3e-246 M Glycosyl transferase family group 2
MHPHHPDM_00091 1.8e-66
MHPHHPDM_00092 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
MHPHHPDM_00093 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_00094 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MHPHHPDM_00095 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHPHHPDM_00096 9.9e-216 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHPHHPDM_00097 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MHPHHPDM_00098 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MHPHHPDM_00099 5.1e-227
MHPHHPDM_00100 4.6e-275 lldP C L-lactate permease
MHPHHPDM_00101 4.1e-59
MHPHHPDM_00102 3.5e-123
MHPHHPDM_00103 3.2e-245 cycA E Amino acid permease
MHPHHPDM_00104 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
MHPHHPDM_00105 4.6e-129 yejC S Protein of unknown function (DUF1003)
MHPHHPDM_00106 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
MHPHHPDM_00107 4.6e-12
MHPHHPDM_00108 1.6e-211 pmrB EGP Major facilitator Superfamily
MHPHHPDM_00109 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
MHPHHPDM_00110 1.4e-49
MHPHHPDM_00111 1.6e-09
MHPHHPDM_00112 2.9e-131 S Protein of unknown function (DUF975)
MHPHHPDM_00113 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MHPHHPDM_00114 2.1e-160 degV S EDD domain protein, DegV family
MHPHHPDM_00115 1.9e-66 K Transcriptional regulator
MHPHHPDM_00116 0.0 FbpA K Fibronectin-binding protein
MHPHHPDM_00117 9.3e-133 S ABC-2 family transporter protein
MHPHHPDM_00118 5.4e-164 V ABC transporter, ATP-binding protein
MHPHHPDM_00119 3e-92 3.6.1.55 F NUDIX domain
MHPHHPDM_00120 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
MHPHHPDM_00121 1.2e-69 S LuxR family transcriptional regulator
MHPHHPDM_00122 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
MHPHHPDM_00125 3.1e-71 frataxin S Domain of unknown function (DU1801)
MHPHHPDM_00126 5.5e-112 pgm5 G Phosphoglycerate mutase family
MHPHHPDM_00127 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MHPHHPDM_00128 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
MHPHHPDM_00129 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHPHHPDM_00130 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHPHHPDM_00131 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MHPHHPDM_00132 1.1e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MHPHHPDM_00133 2.2e-61 esbA S Family of unknown function (DUF5322)
MHPHHPDM_00134 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
MHPHHPDM_00135 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
MHPHHPDM_00136 5.9e-146 S hydrolase activity, acting on ester bonds
MHPHHPDM_00137 2.3e-193
MHPHHPDM_00138 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
MHPHHPDM_00139 1.3e-123
MHPHHPDM_00140 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
MHPHHPDM_00141 2.6e-239 M hydrolase, family 25
MHPHHPDM_00142 6.8e-53
MHPHHPDM_00143 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MHPHHPDM_00144 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MHPHHPDM_00145 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MHPHHPDM_00146 2.6e-39 ylqC S Belongs to the UPF0109 family
MHPHHPDM_00147 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MHPHHPDM_00148 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MHPHHPDM_00149 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MHPHHPDM_00150 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MHPHHPDM_00151 0.0 smc D Required for chromosome condensation and partitioning
MHPHHPDM_00152 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MHPHHPDM_00153 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHPHHPDM_00154 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MHPHHPDM_00155 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MHPHHPDM_00156 0.0 yloV S DAK2 domain fusion protein YloV
MHPHHPDM_00157 1.8e-57 asp S Asp23 family, cell envelope-related function
MHPHHPDM_00158 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MHPHHPDM_00159 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
MHPHHPDM_00160 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MHPHHPDM_00161 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHPHHPDM_00162 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MHPHHPDM_00163 1.7e-134 stp 3.1.3.16 T phosphatase
MHPHHPDM_00164 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MHPHHPDM_00165 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MHPHHPDM_00166 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MHPHHPDM_00167 8.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MHPHHPDM_00168 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MHPHHPDM_00169 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MHPHHPDM_00170 4.5e-55
MHPHHPDM_00171 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
MHPHHPDM_00172 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPHHPDM_00173 1.2e-104 opuCB E ABC transporter permease
MHPHHPDM_00174 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
MHPHHPDM_00175 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
MHPHHPDM_00176 2.2e-76 argR K Regulates arginine biosynthesis genes
MHPHHPDM_00177 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MHPHHPDM_00178 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHPHHPDM_00179 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPHHPDM_00180 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MHPHHPDM_00181 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MHPHHPDM_00182 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MHPHHPDM_00183 3.5e-74 yqhY S Asp23 family, cell envelope-related function
MHPHHPDM_00184 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MHPHHPDM_00185 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MHPHHPDM_00186 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MHPHHPDM_00187 3.2e-53 ysxB J Cysteine protease Prp
MHPHHPDM_00188 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MHPHHPDM_00189 1.8e-89 K Transcriptional regulator
MHPHHPDM_00190 5.4e-19
MHPHHPDM_00193 1.7e-30
MHPHHPDM_00194 5.3e-56
MHPHHPDM_00195 2.4e-98 dut S Protein conserved in bacteria
MHPHHPDM_00196 4e-181
MHPHHPDM_00197 2e-161
MHPHHPDM_00198 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
MHPHHPDM_00199 4.6e-64 glnR K Transcriptional regulator
MHPHHPDM_00200 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MHPHHPDM_00201 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
MHPHHPDM_00202 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
MHPHHPDM_00203 4.4e-68 yqhL P Rhodanese-like protein
MHPHHPDM_00204 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
MHPHHPDM_00205 5.7e-180 glk 2.7.1.2 G Glucokinase
MHPHHPDM_00206 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
MHPHHPDM_00207 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
MHPHHPDM_00208 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MHPHHPDM_00209 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHPHHPDM_00210 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MHPHHPDM_00211 0.0 S membrane
MHPHHPDM_00212 1.5e-54 yneR S Belongs to the HesB IscA family
MHPHHPDM_00213 4e-75 XK27_02470 K LytTr DNA-binding domain
MHPHHPDM_00214 2.3e-96 liaI S membrane
MHPHHPDM_00215 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHPHHPDM_00216 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
MHPHHPDM_00217 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MHPHHPDM_00218 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPHHPDM_00219 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MHPHHPDM_00220 1.1e-62 yodB K Transcriptional regulator, HxlR family
MHPHHPDM_00221 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPHHPDM_00222 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPHHPDM_00223 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MHPHHPDM_00224 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPHHPDM_00225 9.3e-93 S SdpI/YhfL protein family
MHPHHPDM_00226 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MHPHHPDM_00227 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MHPHHPDM_00228 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MHPHHPDM_00229 8e-307 arlS 2.7.13.3 T Histidine kinase
MHPHHPDM_00230 4.3e-121 K response regulator
MHPHHPDM_00231 1.2e-244 rarA L recombination factor protein RarA
MHPHHPDM_00232 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MHPHHPDM_00233 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPHHPDM_00234 7e-88 S Peptidase propeptide and YPEB domain
MHPHHPDM_00235 1.6e-97 yceD S Uncharacterized ACR, COG1399
MHPHHPDM_00236 3.4e-219 ylbM S Belongs to the UPF0348 family
MHPHHPDM_00237 4.4e-140 yqeM Q Methyltransferase
MHPHHPDM_00238 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MHPHHPDM_00239 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MHPHHPDM_00240 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MHPHHPDM_00241 1.1e-50 yhbY J RNA-binding protein
MHPHHPDM_00242 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
MHPHHPDM_00243 1.4e-98 yqeG S HAD phosphatase, family IIIA
MHPHHPDM_00244 1.3e-79
MHPHHPDM_00245 6.9e-222 pgaC GT2 M Glycosyl transferase
MHPHHPDM_00246 2.2e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MHPHHPDM_00247 1e-62 hxlR K Transcriptional regulator, HxlR family
MHPHHPDM_00248 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHPHHPDM_00249 5e-240 yrvN L AAA C-terminal domain
MHPHHPDM_00250 1.1e-55
MHPHHPDM_00251 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MHPHHPDM_00252 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MHPHHPDM_00253 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MHPHHPDM_00254 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MHPHHPDM_00255 1.2e-171 dnaI L Primosomal protein DnaI
MHPHHPDM_00256 1.1e-248 dnaB L replication initiation and membrane attachment
MHPHHPDM_00257 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MHPHHPDM_00258 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MHPHHPDM_00259 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MHPHHPDM_00260 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MHPHHPDM_00261 4.5e-121 ybhL S Belongs to the BI1 family
MHPHHPDM_00262 3.1e-111 hipB K Helix-turn-helix
MHPHHPDM_00263 5.5e-45 yitW S Iron-sulfur cluster assembly protein
MHPHHPDM_00264 1.4e-272 sufB O assembly protein SufB
MHPHHPDM_00265 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
MHPHHPDM_00266 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MHPHHPDM_00267 2.6e-244 sufD O FeS assembly protein SufD
MHPHHPDM_00268 4.2e-144 sufC O FeS assembly ATPase SufC
MHPHHPDM_00269 1.3e-34 feoA P FeoA domain
MHPHHPDM_00270 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MHPHHPDM_00271 7.9e-21 S Virus attachment protein p12 family
MHPHHPDM_00272 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MHPHHPDM_00273 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MHPHHPDM_00274 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MHPHHPDM_00275 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
MHPHHPDM_00276 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MHPHHPDM_00277 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MHPHHPDM_00278 6.2e-224 ecsB U ABC transporter
MHPHHPDM_00279 1.6e-134 ecsA V ABC transporter, ATP-binding protein
MHPHHPDM_00280 9.9e-82 hit FG histidine triad
MHPHHPDM_00281 2e-42
MHPHHPDM_00282 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHPHHPDM_00283 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
MHPHHPDM_00284 3.5e-78 S WxL domain surface cell wall-binding
MHPHHPDM_00285 4e-103 S WxL domain surface cell wall-binding
MHPHHPDM_00286 9.3e-192 S Fn3-like domain
MHPHHPDM_00287 3.5e-61
MHPHHPDM_00288 0.0
MHPHHPDM_00289 2.1e-241 npr 1.11.1.1 C NADH oxidase
MHPHHPDM_00290 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPHHPDM_00291 9.8e-28
MHPHHPDM_00292 8.4e-145 yjfP S Dienelactone hydrolase family
MHPHHPDM_00293 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
MHPHHPDM_00294 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MHPHHPDM_00295 5.2e-47
MHPHHPDM_00296 1.7e-45
MHPHHPDM_00297 5e-82 yybC S Protein of unknown function (DUF2798)
MHPHHPDM_00298 3.7e-73
MHPHHPDM_00299 4e-60
MHPHHPDM_00300 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
MHPHHPDM_00301 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
MHPHHPDM_00302 1.6e-79 uspA T universal stress protein
MHPHHPDM_00303 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MHPHHPDM_00304 1.7e-48 K Cro/C1-type HTH DNA-binding domain
MHPHHPDM_00305 3.3e-21 S Protein of unknown function (DUF2929)
MHPHHPDM_00306 2.3e-223 lsgC M Glycosyl transferases group 1
MHPHHPDM_00307 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MHPHHPDM_00308 2.3e-164 S Putative esterase
MHPHHPDM_00309 2.4e-130 gntR2 K Transcriptional regulator
MHPHHPDM_00310 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MHPHHPDM_00311 1.5e-138
MHPHHPDM_00312 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPHHPDM_00313 5.5e-138 rrp8 K LytTr DNA-binding domain
MHPHHPDM_00314 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
MHPHHPDM_00315 7.7e-61
MHPHHPDM_00316 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
MHPHHPDM_00317 4.4e-58
MHPHHPDM_00318 1.2e-239 yhdP S Transporter associated domain
MHPHHPDM_00319 4.9e-87 nrdI F Belongs to the NrdI family
MHPHHPDM_00320 2.9e-269 yjcE P Sodium proton antiporter
MHPHHPDM_00321 2.8e-213 yttB EGP Major facilitator Superfamily
MHPHHPDM_00322 5e-63 K helix_turn_helix, mercury resistance
MHPHHPDM_00323 3e-30 C Zinc-binding dehydrogenase
MHPHHPDM_00324 1.9e-127 C Zinc-binding dehydrogenase
MHPHHPDM_00325 8.5e-57 S SdpI/YhfL protein family
MHPHHPDM_00326 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MHPHHPDM_00327 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
MHPHHPDM_00328 5e-218 patA 2.6.1.1 E Aminotransferase
MHPHHPDM_00329 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHPHHPDM_00330 3e-18
MHPHHPDM_00331 1.7e-126 S membrane transporter protein
MHPHHPDM_00332 7.3e-161 mleR K LysR family
MHPHHPDM_00333 5.6e-115 ylbE GM NAD(P)H-binding
MHPHHPDM_00334 8.2e-96 wecD K Acetyltransferase (GNAT) family
MHPHHPDM_00335 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MHPHHPDM_00336 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MHPHHPDM_00337 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
MHPHHPDM_00338 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MHPHHPDM_00339 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MHPHHPDM_00340 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MHPHHPDM_00341 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MHPHHPDM_00342 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHPHHPDM_00343 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MHPHHPDM_00344 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MHPHHPDM_00345 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MHPHHPDM_00346 1e-298 pucR QT Purine catabolism regulatory protein-like family
MHPHHPDM_00347 2.7e-236 pbuX F xanthine permease
MHPHHPDM_00348 2.4e-221 pbuG S Permease family
MHPHHPDM_00349 5.6e-161 GM NmrA-like family
MHPHHPDM_00350 6.5e-156 T EAL domain
MHPHHPDM_00351 2.6e-94
MHPHHPDM_00352 9.2e-253 pgaC GT2 M Glycosyl transferase
MHPHHPDM_00353 1e-122 2.1.1.14 E Methionine synthase
MHPHHPDM_00354 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
MHPHHPDM_00355 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MHPHHPDM_00356 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MHPHHPDM_00357 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MHPHHPDM_00358 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MHPHHPDM_00359 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPHHPDM_00360 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPHHPDM_00361 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MHPHHPDM_00362 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MHPHHPDM_00363 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MHPHHPDM_00364 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MHPHHPDM_00365 4.3e-223 XK27_09615 1.3.5.4 S reductase
MHPHHPDM_00366 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
MHPHHPDM_00367 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
MHPHHPDM_00368 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
MHPHHPDM_00369 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MHPHHPDM_00370 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_00371 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
MHPHHPDM_00372 1.7e-139 cysA V ABC transporter, ATP-binding protein
MHPHHPDM_00373 0.0 V FtsX-like permease family
MHPHHPDM_00374 7.4e-40
MHPHHPDM_00375 7.9e-61 gntR1 K Transcriptional regulator, GntR family
MHPHHPDM_00376 6.9e-164 V ABC transporter, ATP-binding protein
MHPHHPDM_00377 5.1e-137
MHPHHPDM_00378 1.9e-80 uspA T universal stress protein
MHPHHPDM_00379 4e-34
MHPHHPDM_00380 5.5e-71 gtcA S Teichoic acid glycosylation protein
MHPHHPDM_00381 1.1e-88
MHPHHPDM_00382 3.2e-50
MHPHHPDM_00384 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
MHPHHPDM_00385 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
MHPHHPDM_00386 5.4e-118
MHPHHPDM_00387 1.5e-52
MHPHHPDM_00389 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MHPHHPDM_00390 1.1e-281 thrC 4.2.3.1 E Threonine synthase
MHPHHPDM_00391 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
MHPHHPDM_00392 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
MHPHHPDM_00393 2.5e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MHPHHPDM_00394 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
MHPHHPDM_00395 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
MHPHHPDM_00396 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
MHPHHPDM_00397 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
MHPHHPDM_00398 1.4e-211 S Bacterial protein of unknown function (DUF871)
MHPHHPDM_00399 2.1e-232 S Sterol carrier protein domain
MHPHHPDM_00400 3.6e-88 niaR S 3H domain
MHPHHPDM_00401 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHPHHPDM_00402 2.8e-117 K Transcriptional regulator
MHPHHPDM_00403 1.1e-151 V ABC transporter
MHPHHPDM_00404 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
MHPHHPDM_00405 4.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MHPHHPDM_00406 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_00407 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_00408 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MHPHHPDM_00409 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_00410 9.9e-129 gntR K UTRA
MHPHHPDM_00411 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
MHPHHPDM_00412 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MHPHHPDM_00413 1.8e-81
MHPHHPDM_00414 9.8e-152 S hydrolase
MHPHHPDM_00415 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPHHPDM_00416 1.4e-151 EG EamA-like transporter family
MHPHHPDM_00417 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MHPHHPDM_00418 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MHPHHPDM_00419 6.5e-232
MHPHHPDM_00420 4.2e-77 fld C Flavodoxin
MHPHHPDM_00421 0.0 M Bacterial Ig-like domain (group 3)
MHPHHPDM_00422 6.2e-149 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MHPHHPDM_00423 4.1e-283 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MHPHHPDM_00424 2.7e-32
MHPHHPDM_00425 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
MHPHHPDM_00426 6.4e-268 ycaM E amino acid
MHPHHPDM_00427 8.7e-78 K Winged helix DNA-binding domain
MHPHHPDM_00428 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
MHPHHPDM_00429 1.1e-161 akr5f 1.1.1.346 S reductase
MHPHHPDM_00430 3.9e-162 K Transcriptional regulator
MHPHHPDM_00432 1.6e-75 yugI 5.3.1.9 J general stress protein
MHPHHPDM_00433 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MHPHHPDM_00434 1.9e-118 dedA S SNARE-like domain protein
MHPHHPDM_00435 1.8e-116 S Protein of unknown function (DUF1461)
MHPHHPDM_00436 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MHPHHPDM_00437 1.5e-80 yutD S Protein of unknown function (DUF1027)
MHPHHPDM_00438 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MHPHHPDM_00439 4.4e-117 S Calcineurin-like phosphoesterase
MHPHHPDM_00440 5.3e-251 cycA E Amino acid permease
MHPHHPDM_00441 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPHHPDM_00442 4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
MHPHHPDM_00444 4.5e-88 S Prokaryotic N-terminal methylation motif
MHPHHPDM_00445 8.6e-20
MHPHHPDM_00446 3.2e-83 gspG NU general secretion pathway protein
MHPHHPDM_00447 5.5e-43 comGC U competence protein ComGC
MHPHHPDM_00448 1.9e-189 comGB NU type II secretion system
MHPHHPDM_00449 2.1e-174 comGA NU Type II IV secretion system protein
MHPHHPDM_00450 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHPHHPDM_00451 8.3e-131 yebC K Transcriptional regulatory protein
MHPHHPDM_00452 1.6e-49 S DsrE/DsrF-like family
MHPHHPDM_00453 6.8e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MHPHHPDM_00454 1.9e-181 ccpA K catabolite control protein A
MHPHHPDM_00455 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MHPHHPDM_00456 1.9e-62 K helix_turn_helix, mercury resistance
MHPHHPDM_00457 2.8e-56
MHPHHPDM_00458 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MHPHHPDM_00459 2.6e-158 ykuT M mechanosensitive ion channel
MHPHHPDM_00460 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MHPHHPDM_00461 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MHPHHPDM_00462 6.5e-87 ykuL S (CBS) domain
MHPHHPDM_00463 9.5e-97 S Phosphoesterase
MHPHHPDM_00464 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MHPHHPDM_00465 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MHPHHPDM_00466 7.6e-126 yslB S Protein of unknown function (DUF2507)
MHPHHPDM_00467 3.3e-52 trxA O Belongs to the thioredoxin family
MHPHHPDM_00468 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MHPHHPDM_00469 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MHPHHPDM_00470 1.6e-48 yrzB S Belongs to the UPF0473 family
MHPHHPDM_00471 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MHPHHPDM_00472 2.4e-43 yrzL S Belongs to the UPF0297 family
MHPHHPDM_00473 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MHPHHPDM_00474 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MHPHHPDM_00475 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MHPHHPDM_00476 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MHPHHPDM_00477 2.8e-29 yajC U Preprotein translocase
MHPHHPDM_00478 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MHPHHPDM_00479 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MHPHHPDM_00480 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MHPHHPDM_00481 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MHPHHPDM_00482 9.6e-89
MHPHHPDM_00483 0.0 S Bacterial membrane protein YfhO
MHPHHPDM_00484 3.1e-71
MHPHHPDM_00485 0.0 L Transposase
MHPHHPDM_00486 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MHPHHPDM_00487 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MHPHHPDM_00488 2.7e-154 ymdB S YmdB-like protein
MHPHHPDM_00489 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
MHPHHPDM_00490 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MHPHHPDM_00491 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
MHPHHPDM_00492 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MHPHHPDM_00493 5.7e-110 ymfM S Helix-turn-helix domain
MHPHHPDM_00494 2.9e-251 ymfH S Peptidase M16
MHPHHPDM_00495 1.9e-231 ymfF S Peptidase M16 inactive domain protein
MHPHHPDM_00496 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
MHPHHPDM_00497 1.5e-155 aatB ET ABC transporter substrate-binding protein
MHPHHPDM_00498 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_00499 4.6e-109 glnP P ABC transporter permease
MHPHHPDM_00500 1.2e-146 minD D Belongs to the ParA family
MHPHHPDM_00501 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MHPHHPDM_00502 1.2e-88 mreD M rod shape-determining protein MreD
MHPHHPDM_00503 2.6e-144 mreC M Involved in formation and maintenance of cell shape
MHPHHPDM_00504 2.8e-161 mreB D cell shape determining protein MreB
MHPHHPDM_00505 1.3e-116 radC L DNA repair protein
MHPHHPDM_00506 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHPHHPDM_00507 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MHPHHPDM_00508 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MHPHHPDM_00509 1.2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MHPHHPDM_00510 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MHPHHPDM_00511 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
MHPHHPDM_00512 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MHPHHPDM_00513 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
MHPHHPDM_00514 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MHPHHPDM_00515 5.2e-113 yktB S Belongs to the UPF0637 family
MHPHHPDM_00516 7.3e-80 yueI S Protein of unknown function (DUF1694)
MHPHHPDM_00517 2.2e-108 S Protein of unknown function (DUF1648)
MHPHHPDM_00518 1.9e-43 czrA K Helix-turn-helix domain
MHPHHPDM_00519 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MHPHHPDM_00520 8e-238 rarA L recombination factor protein RarA
MHPHHPDM_00521 1.5e-38
MHPHHPDM_00522 6.2e-82 usp6 T universal stress protein
MHPHHPDM_00523 6.3e-202 bla2 3.5.2.6 V Beta-lactamase enzyme family
MHPHHPDM_00524 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_00525 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MHPHHPDM_00526 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MHPHHPDM_00527 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MHPHHPDM_00528 1.6e-177 S Protein of unknown function (DUF2785)
MHPHHPDM_00529 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
MHPHHPDM_00530 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
MHPHHPDM_00531 1.4e-111 metI U ABC transporter permease
MHPHHPDM_00532 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPHHPDM_00533 3.6e-48 gcsH2 E glycine cleavage
MHPHHPDM_00534 9.3e-220 rodA D Belongs to the SEDS family
MHPHHPDM_00535 1.2e-32 S Protein of unknown function (DUF2969)
MHPHHPDM_00536 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MHPHHPDM_00537 2.7e-180 mbl D Cell shape determining protein MreB Mrl
MHPHHPDM_00538 2.1e-102 J Acetyltransferase (GNAT) domain
MHPHHPDM_00539 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPHHPDM_00540 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MHPHHPDM_00541 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MHPHHPDM_00542 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MHPHHPDM_00543 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MHPHHPDM_00544 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPHHPDM_00545 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MHPHHPDM_00546 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MHPHHPDM_00547 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MHPHHPDM_00548 3e-232 pyrP F Permease
MHPHHPDM_00549 3.4e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
MHPHHPDM_00550 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MHPHHPDM_00551 1.3e-128 K Helix-turn-helix domain, rpiR family
MHPHHPDM_00552 8.5e-159 S Alpha beta hydrolase
MHPHHPDM_00553 9.9e-112 GM NmrA-like family
MHPHHPDM_00554 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
MHPHHPDM_00555 1.9e-161 K Transcriptional regulator
MHPHHPDM_00556 1.9e-172 C nadph quinone reductase
MHPHHPDM_00557 6.3e-14 S Alpha beta hydrolase
MHPHHPDM_00558 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHPHHPDM_00559 4e-102 desR K helix_turn_helix, Lux Regulon
MHPHHPDM_00560 2.8e-207 desK 2.7.13.3 T Histidine kinase
MHPHHPDM_00561 3.1e-136 yvfS V ABC-2 type transporter
MHPHHPDM_00562 5.2e-159 yvfR V ABC transporter
MHPHHPDM_00564 6e-82 K Acetyltransferase (GNAT) domain
MHPHHPDM_00565 2.4e-72 K MarR family
MHPHHPDM_00566 3.8e-114 S Psort location CytoplasmicMembrane, score
MHPHHPDM_00567 2.6e-12 yjdF S Protein of unknown function (DUF2992)
MHPHHPDM_00568 5.6e-161 V ABC transporter, ATP-binding protein
MHPHHPDM_00569 5.2e-128 S ABC-2 family transporter protein
MHPHHPDM_00570 1.5e-197
MHPHHPDM_00571 5.9e-202
MHPHHPDM_00572 4.8e-165 ytrB V ABC transporter, ATP-binding protein
MHPHHPDM_00573 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
MHPHHPDM_00574 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MHPHHPDM_00575 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MHPHHPDM_00576 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MHPHHPDM_00577 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MHPHHPDM_00578 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
MHPHHPDM_00579 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MHPHHPDM_00580 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MHPHHPDM_00581 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MHPHHPDM_00582 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
MHPHHPDM_00583 2.6e-71 yqeY S YqeY-like protein
MHPHHPDM_00584 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MHPHHPDM_00585 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MHPHHPDM_00586 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
MHPHHPDM_00587 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MHPHHPDM_00588 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHPHHPDM_00589 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MHPHHPDM_00590 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHPHHPDM_00591 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MHPHHPDM_00592 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MHPHHPDM_00593 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MHPHHPDM_00594 1.6e-160 yniA G Fructosamine kinase
MHPHHPDM_00595 6.5e-116 3.1.3.18 J HAD-hyrolase-like
MHPHHPDM_00596 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MHPHHPDM_00597 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MHPHHPDM_00598 9.6e-58
MHPHHPDM_00599 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MHPHHPDM_00600 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
MHPHHPDM_00601 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MHPHHPDM_00602 1.4e-49
MHPHHPDM_00603 1.4e-49
MHPHHPDM_00606 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
MHPHHPDM_00607 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHPHHPDM_00608 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MHPHHPDM_00609 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPHHPDM_00610 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MHPHHPDM_00611 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPHHPDM_00612 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
MHPHHPDM_00613 4.4e-198 pbpX2 V Beta-lactamase
MHPHHPDM_00614 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MHPHHPDM_00615 0.0 dnaK O Heat shock 70 kDa protein
MHPHHPDM_00616 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MHPHHPDM_00617 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MHPHHPDM_00618 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MHPHHPDM_00619 1.7e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHPHHPDM_00620 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MHPHHPDM_00621 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MHPHHPDM_00622 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MHPHHPDM_00623 2.5e-223 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MHPHHPDM_00624 8.5e-93
MHPHHPDM_00625 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MHPHHPDM_00626 2e-264 ydiN 5.4.99.5 G Major Facilitator
MHPHHPDM_00627 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MHPHHPDM_00628 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MHPHHPDM_00629 3.1e-47 ylxQ J ribosomal protein
MHPHHPDM_00630 9.5e-49 ylxR K Protein of unknown function (DUF448)
MHPHHPDM_00631 3.3e-217 nusA K Participates in both transcription termination and antitermination
MHPHHPDM_00632 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
MHPHHPDM_00633 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPHHPDM_00634 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MHPHHPDM_00635 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MHPHHPDM_00636 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MHPHHPDM_00637 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MHPHHPDM_00638 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MHPHHPDM_00639 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MHPHHPDM_00640 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MHPHHPDM_00641 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MHPHHPDM_00642 4.7e-134 S Haloacid dehalogenase-like hydrolase
MHPHHPDM_00643 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPHHPDM_00644 7e-39 yazA L GIY-YIG catalytic domain protein
MHPHHPDM_00645 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
MHPHHPDM_00646 6.4e-119 plsC 2.3.1.51 I Acyltransferase
MHPHHPDM_00647 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
MHPHHPDM_00648 2.9e-36 ynzC S UPF0291 protein
MHPHHPDM_00649 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MHPHHPDM_00650 3.7e-87
MHPHHPDM_00651 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MHPHHPDM_00652 4.6e-75
MHPHHPDM_00653 3e-66
MHPHHPDM_00654 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
MHPHHPDM_00655 9.2e-101 L Helix-turn-helix domain
MHPHHPDM_00656 2.4e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
MHPHHPDM_00657 7.9e-143 P ATPases associated with a variety of cellular activities
MHPHHPDM_00658 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MHPHHPDM_00659 2.2e-229 rodA D Cell cycle protein
MHPHHPDM_00661 3.3e-307 uup S ABC transporter, ATP-binding protein
MHPHHPDM_00662 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MHPHHPDM_00663 6.1e-109 ydiL S CAAX protease self-immunity
MHPHHPDM_00664 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MHPHHPDM_00665 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MHPHHPDM_00666 0.0 ydaO E amino acid
MHPHHPDM_00667 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
MHPHHPDM_00668 4.3e-145 pstS P Phosphate
MHPHHPDM_00669 1.7e-114 yvyE 3.4.13.9 S YigZ family
MHPHHPDM_00670 9.6e-258 comFA L Helicase C-terminal domain protein
MHPHHPDM_00671 7.5e-126 comFC S Competence protein
MHPHHPDM_00672 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MHPHHPDM_00673 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MHPHHPDM_00674 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MHPHHPDM_00675 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MHPHHPDM_00676 1.5e-132 K response regulator
MHPHHPDM_00677 3.5e-250 phoR 2.7.13.3 T Histidine kinase
MHPHHPDM_00678 2.1e-149 pstS P Phosphate
MHPHHPDM_00679 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
MHPHHPDM_00680 1.5e-155 pstA P Phosphate transport system permease protein PstA
MHPHHPDM_00681 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPHHPDM_00682 3.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MHPHHPDM_00683 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
MHPHHPDM_00684 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
MHPHHPDM_00685 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MHPHHPDM_00686 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MHPHHPDM_00687 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MHPHHPDM_00688 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MHPHHPDM_00689 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MHPHHPDM_00690 1.9e-124 yliE T Putative diguanylate phosphodiesterase
MHPHHPDM_00691 3.9e-270 nox C NADH oxidase
MHPHHPDM_00692 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MHPHHPDM_00693 2e-109 yviA S Protein of unknown function (DUF421)
MHPHHPDM_00694 1.1e-61 S Protein of unknown function (DUF3290)
MHPHHPDM_00695 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MHPHHPDM_00696 3.3e-132 yliE T Putative diguanylate phosphodiesterase
MHPHHPDM_00697 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MHPHHPDM_00698 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MHPHHPDM_00699 9.2e-212 norA EGP Major facilitator Superfamily
MHPHHPDM_00700 3.6e-117 yfbR S HD containing hydrolase-like enzyme
MHPHHPDM_00701 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MHPHHPDM_00702 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MHPHHPDM_00703 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MHPHHPDM_00704 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MHPHHPDM_00705 7.9e-263 argH 4.3.2.1 E argininosuccinate lyase
MHPHHPDM_00706 3.5e-86 S Short repeat of unknown function (DUF308)
MHPHHPDM_00707 1.1e-161 rapZ S Displays ATPase and GTPase activities
MHPHHPDM_00708 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MHPHHPDM_00709 3.7e-168 whiA K May be required for sporulation
MHPHHPDM_00710 9.9e-289 oppA E ABC transporter, substratebinding protein
MHPHHPDM_00711 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPHHPDM_00712 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MHPHHPDM_00714 4.2e-245 rpoN K Sigma-54 factor, core binding domain
MHPHHPDM_00715 7.3e-189 cggR K Putative sugar-binding domain
MHPHHPDM_00716 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MHPHHPDM_00717 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MHPHHPDM_00718 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MHPHHPDM_00719 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MHPHHPDM_00720 2e-131
MHPHHPDM_00721 6.6e-295 clcA P chloride
MHPHHPDM_00722 3.5e-30 secG U Preprotein translocase
MHPHHPDM_00723 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
MHPHHPDM_00724 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MHPHHPDM_00725 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MHPHHPDM_00726 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
MHPHHPDM_00727 1.5e-256 glnP P ABC transporter
MHPHHPDM_00728 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_00729 6.1e-105 yxjI
MHPHHPDM_00730 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
MHPHHPDM_00731 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MHPHHPDM_00732 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MHPHHPDM_00733 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MHPHHPDM_00734 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
MHPHHPDM_00735 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
MHPHHPDM_00736 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
MHPHHPDM_00737 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MHPHHPDM_00738 6.2e-168 murB 1.3.1.98 M Cell wall formation
MHPHHPDM_00739 0.0 yjcE P Sodium proton antiporter
MHPHHPDM_00740 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_00741 2.1e-120 S Protein of unknown function (DUF1361)
MHPHHPDM_00742 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MHPHHPDM_00743 1.6e-129 ybbR S YbbR-like protein
MHPHHPDM_00744 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MHPHHPDM_00745 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MHPHHPDM_00746 4e-65 padC Q Phenolic acid decarboxylase
MHPHHPDM_00747 6.7e-142 tesE Q hydratase
MHPHHPDM_00748 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
MHPHHPDM_00749 2.8e-157 degV S DegV family
MHPHHPDM_00750 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
MHPHHPDM_00751 1.5e-255 pepC 3.4.22.40 E aminopeptidase
MHPHHPDM_00753 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHPHHPDM_00754 1.1e-302
MHPHHPDM_00756 3e-158 S Bacterial protein of unknown function (DUF916)
MHPHHPDM_00757 5.9e-92 S Cell surface protein
MHPHHPDM_00758 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MHPHHPDM_00759 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MHPHHPDM_00760 9.1e-109 jag S R3H domain protein
MHPHHPDM_00761 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
MHPHHPDM_00762 1e-309 E ABC transporter, substratebinding protein
MHPHHPDM_00763 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MHPHHPDM_00764 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MHPHHPDM_00765 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MHPHHPDM_00766 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MHPHHPDM_00767 5e-37 yaaA S S4 domain protein YaaA
MHPHHPDM_00768 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MHPHHPDM_00769 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPHHPDM_00770 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MHPHHPDM_00771 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MHPHHPDM_00772 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MHPHHPDM_00773 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MHPHHPDM_00774 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MHPHHPDM_00775 1.4e-67 rplI J Binds to the 23S rRNA
MHPHHPDM_00776 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MHPHHPDM_00777 8.8e-226 yttB EGP Major facilitator Superfamily
MHPHHPDM_00778 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MHPHHPDM_00779 1.2e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MHPHHPDM_00781 4.2e-276 E ABC transporter, substratebinding protein
MHPHHPDM_00782 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MHPHHPDM_00783 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MHPHHPDM_00784 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MHPHHPDM_00785 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MHPHHPDM_00786 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MHPHHPDM_00787 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MHPHHPDM_00788 4.5e-143 S haloacid dehalogenase-like hydrolase
MHPHHPDM_00789 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MHPHHPDM_00790 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
MHPHHPDM_00791 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
MHPHHPDM_00792 1.6e-31 cspA K Cold shock protein domain
MHPHHPDM_00793 1.7e-37
MHPHHPDM_00795 6.2e-131 K response regulator
MHPHHPDM_00796 0.0 vicK 2.7.13.3 T Histidine kinase
MHPHHPDM_00797 1.2e-244 yycH S YycH protein
MHPHHPDM_00798 2.2e-151 yycI S YycH protein
MHPHHPDM_00799 8.9e-158 vicX 3.1.26.11 S domain protein
MHPHHPDM_00800 6.8e-173 htrA 3.4.21.107 O serine protease
MHPHHPDM_00801 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MHPHHPDM_00802 1.5e-95 K Bacterial regulatory proteins, tetR family
MHPHHPDM_00803 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
MHPHHPDM_00804 7.2e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MHPHHPDM_00805 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
MHPHHPDM_00806 4.2e-32 pnb C nitroreductase
MHPHHPDM_00807 5.7e-67 pnb C nitroreductase
MHPHHPDM_00808 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MHPHHPDM_00809 1.8e-116 S Elongation factor G-binding protein, N-terminal
MHPHHPDM_00810 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
MHPHHPDM_00811 1.3e-257 P Sodium:sulfate symporter transmembrane region
MHPHHPDM_00812 5.7e-158 K LysR family
MHPHHPDM_00813 1e-72 C FMN binding
MHPHHPDM_00814 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MHPHHPDM_00815 2.3e-164 ptlF S KR domain
MHPHHPDM_00816 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MHPHHPDM_00817 1.3e-122 drgA C Nitroreductase family
MHPHHPDM_00818 1.3e-290 QT PucR C-terminal helix-turn-helix domain
MHPHHPDM_00819 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MHPHHPDM_00820 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPHHPDM_00821 7.4e-250 yjjP S Putative threonine/serine exporter
MHPHHPDM_00822 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
MHPHHPDM_00823 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
MHPHHPDM_00824 2.9e-81 6.3.3.2 S ASCH
MHPHHPDM_00825 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
MHPHHPDM_00826 5.5e-172 yobV1 K WYL domain
MHPHHPDM_00827 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPHHPDM_00828 0.0 tetP J elongation factor G
MHPHHPDM_00829 8.2e-39 S Protein of unknown function
MHPHHPDM_00830 2.1e-61 S Protein of unknown function
MHPHHPDM_00831 8e-152 EG EamA-like transporter family
MHPHHPDM_00832 3.6e-93 MA20_25245 K FR47-like protein
MHPHHPDM_00833 2e-126 hchA S DJ-1/PfpI family
MHPHHPDM_00834 5.4e-181 1.1.1.1 C nadph quinone reductase
MHPHHPDM_00835 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_00836 2.3e-235 mepA V MATE efflux family protein
MHPHHPDM_00837 4.7e-20
MHPHHPDM_00838 2.9e-71
MHPHHPDM_00841 2.3e-88
MHPHHPDM_00842 2.7e-139 S Phage minor structural protein
MHPHHPDM_00843 0.0 S Phage tail protein
MHPHHPDM_00844 0.0 D NLP P60 protein
MHPHHPDM_00845 6.6e-24
MHPHHPDM_00846 1.8e-57 S Phage tail assembly chaperone proteins, TAC
MHPHHPDM_00847 3e-103 S Phage tail tube protein
MHPHHPDM_00848 3.5e-56 S Protein of unknown function (DUF806)
MHPHHPDM_00849 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
MHPHHPDM_00850 1.7e-57 S Phage head-tail joining protein
MHPHHPDM_00851 6.2e-49 S Phage gp6-like head-tail connector protein
MHPHHPDM_00852 7.5e-201 S Phage capsid family
MHPHHPDM_00853 6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MHPHHPDM_00854 5.2e-223 S Phage portal protein
MHPHHPDM_00855 2.1e-25 S Protein of unknown function (DUF1056)
MHPHHPDM_00856 0.0 S Phage Terminase
MHPHHPDM_00857 3.6e-79 L Phage terminase, small subunit
MHPHHPDM_00859 6.1e-88 L HNH nucleases
MHPHHPDM_00861 8.2e-65 S Transcriptional regulator, RinA family
MHPHHPDM_00862 1.4e-15
MHPHHPDM_00863 1.4e-55
MHPHHPDM_00864 1.2e-09 S YopX protein
MHPHHPDM_00866 7e-96 2.1.1.37 L C-5 cytosine-specific DNA methylase
MHPHHPDM_00869 3.7e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MHPHHPDM_00871 1.4e-131 pi346 L IstB-like ATP binding protein
MHPHHPDM_00872 1.3e-39 S calcium ion binding
MHPHHPDM_00873 3.9e-130 S Putative HNHc nuclease
MHPHHPDM_00874 1.2e-91 S Protein of unknown function (DUF669)
MHPHHPDM_00875 8.1e-117 S AAA domain
MHPHHPDM_00876 2.8e-146 S Protein of unknown function (DUF1351)
MHPHHPDM_00878 6.3e-18
MHPHHPDM_00885 7.2e-63 S DNA binding
MHPHHPDM_00888 8.8e-20
MHPHHPDM_00889 4.5e-78 K Peptidase S24-like
MHPHHPDM_00896 3.1e-63 L Belongs to the 'phage' integrase family
MHPHHPDM_00897 3.6e-31
MHPHHPDM_00898 1.1e-138 Q Methyltransferase
MHPHHPDM_00899 8.5e-57 ybjQ S Belongs to the UPF0145 family
MHPHHPDM_00900 6.1e-211 EGP Major facilitator Superfamily
MHPHHPDM_00901 1.5e-98 K Helix-turn-helix domain
MHPHHPDM_00902 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MHPHHPDM_00903 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MHPHHPDM_00904 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
MHPHHPDM_00905 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPHHPDM_00906 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MHPHHPDM_00907 3.2e-46
MHPHHPDM_00908 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MHPHHPDM_00909 1.5e-135 fruR K DeoR C terminal sensor domain
MHPHHPDM_00910 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MHPHHPDM_00911 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
MHPHHPDM_00912 3.8e-251 cpdA S Calcineurin-like phosphoesterase
MHPHHPDM_00913 4.5e-261 cps4J S Polysaccharide biosynthesis protein
MHPHHPDM_00914 3e-176 cps4I M Glycosyltransferase like family 2
MHPHHPDM_00915 1.3e-232
MHPHHPDM_00916 6.5e-38 cps4G M Glycosyltransferase Family 4
MHPHHPDM_00917 2.7e-103 cps4G M Glycosyltransferase Family 4
MHPHHPDM_00918 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
MHPHHPDM_00919 7.4e-126 tuaA M Bacterial sugar transferase
MHPHHPDM_00920 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
MHPHHPDM_00921 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
MHPHHPDM_00922 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MHPHHPDM_00923 2.9e-126 epsB M biosynthesis protein
MHPHHPDM_00924 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MHPHHPDM_00925 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_00926 9.2e-270 glnPH2 P ABC transporter permease
MHPHHPDM_00927 4.3e-22
MHPHHPDM_00928 9.9e-73 S Iron-sulphur cluster biosynthesis
MHPHHPDM_00929 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MHPHHPDM_00930 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MHPHHPDM_00931 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MHPHHPDM_00932 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MHPHHPDM_00933 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MHPHHPDM_00934 1e-157 S Tetratricopeptide repeat
MHPHHPDM_00935 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPHHPDM_00936 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MHPHHPDM_00937 7.2e-103 mdtG EGP Major Facilitator Superfamily
MHPHHPDM_00938 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MHPHHPDM_00939 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
MHPHHPDM_00940 7e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
MHPHHPDM_00941 0.0 comEC S Competence protein ComEC
MHPHHPDM_00942 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
MHPHHPDM_00943 6.8e-125 comEA L Competence protein ComEA
MHPHHPDM_00944 9.6e-197 ylbL T Belongs to the peptidase S16 family
MHPHHPDM_00945 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MHPHHPDM_00946 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MHPHHPDM_00947 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MHPHHPDM_00948 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MHPHHPDM_00949 8.2e-205 ftsW D Belongs to the SEDS family
MHPHHPDM_00950 1.2e-286
MHPHHPDM_00951 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
MHPHHPDM_00952 6.4e-156 pelX UW LPXTG-motif cell wall anchor domain protein
MHPHHPDM_00953 5.3e-86
MHPHHPDM_00954 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MHPHHPDM_00955 1.5e-270 XK27_00765
MHPHHPDM_00957 5.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
MHPHHPDM_00958 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
MHPHHPDM_00959 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MHPHHPDM_00960 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MHPHHPDM_00961 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MHPHHPDM_00962 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MHPHHPDM_00963 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MHPHHPDM_00964 2e-97 entB 3.5.1.19 Q Isochorismatase family
MHPHHPDM_00965 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
MHPHHPDM_00966 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
MHPHHPDM_00967 5.8e-217 E glutamate:sodium symporter activity
MHPHHPDM_00968 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
MHPHHPDM_00969 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MHPHHPDM_00970 2.1e-58 S Protein of unknown function (DUF1648)
MHPHHPDM_00972 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPHHPDM_00973 1.1e-178 yneE K Transcriptional regulator
MHPHHPDM_00974 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MHPHHPDM_00975 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPHHPDM_00976 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MHPHHPDM_00977 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MHPHHPDM_00978 2.1e-126 IQ reductase
MHPHHPDM_00979 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MHPHHPDM_00980 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHPHHPDM_00981 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MHPHHPDM_00982 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MHPHHPDM_00983 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHPHHPDM_00984 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MHPHHPDM_00985 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MHPHHPDM_00986 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MHPHHPDM_00987 2.2e-123 S Protein of unknown function (DUF554)
MHPHHPDM_00988 1.6e-160 K LysR substrate binding domain
MHPHHPDM_00989 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
MHPHHPDM_00990 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MHPHHPDM_00991 7.5e-92 K transcriptional regulator
MHPHHPDM_00992 1.4e-301 norB EGP Major Facilitator
MHPHHPDM_00993 1.2e-139 f42a O Band 7 protein
MHPHHPDM_00994 8.5e-54
MHPHHPDM_00995 1.3e-28
MHPHHPDM_00996 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MHPHHPDM_00997 2.3e-29 L hmm pf00665
MHPHHPDM_00998 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
MHPHHPDM_00999 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
MHPHHPDM_01000 7.9e-41
MHPHHPDM_01001 1.9e-67 tspO T TspO/MBR family
MHPHHPDM_01002 6.3e-76 uspA T Belongs to the universal stress protein A family
MHPHHPDM_01003 1e-65 S Protein of unknown function (DUF805)
MHPHHPDM_01004 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
MHPHHPDM_01005 2.9e-35
MHPHHPDM_01006 3.1e-14
MHPHHPDM_01007 6.5e-41 S transglycosylase associated protein
MHPHHPDM_01008 4.8e-29 S CsbD-like
MHPHHPDM_01009 9.4e-40
MHPHHPDM_01010 8.6e-281 pipD E Dipeptidase
MHPHHPDM_01011 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MHPHHPDM_01012 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MHPHHPDM_01013 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
MHPHHPDM_01014 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
MHPHHPDM_01015 1.9e-49
MHPHHPDM_01016 2.1e-42
MHPHHPDM_01017 3.3e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MHPHHPDM_01018 1.4e-265 yfnA E Amino Acid
MHPHHPDM_01019 1.2e-149 yitU 3.1.3.104 S hydrolase
MHPHHPDM_01020 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MHPHHPDM_01021 1.5e-89 S Domain of unknown function (DUF4767)
MHPHHPDM_01022 2.5e-250 malT G Major Facilitator
MHPHHPDM_01023 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MHPHHPDM_01024 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MHPHHPDM_01025 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MHPHHPDM_01026 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MHPHHPDM_01027 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MHPHHPDM_01028 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MHPHHPDM_01029 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MHPHHPDM_01030 2.1e-72 ypmB S protein conserved in bacteria
MHPHHPDM_01031 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MHPHHPDM_01032 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MHPHHPDM_01033 1.1e-127 dnaD L Replication initiation and membrane attachment
MHPHHPDM_01035 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MHPHHPDM_01036 2e-99 metI P ABC transporter permease
MHPHHPDM_01037 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
MHPHHPDM_01038 4.4e-83 uspA T Universal stress protein family
MHPHHPDM_01039 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
MHPHHPDM_01040 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
MHPHHPDM_01041 7e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
MHPHHPDM_01042 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MHPHHPDM_01043 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MHPHHPDM_01044 8.3e-110 ypsA S Belongs to the UPF0398 family
MHPHHPDM_01045 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MHPHHPDM_01047 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MHPHHPDM_01048 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_01049 6.1e-244 P Major Facilitator Superfamily
MHPHHPDM_01050 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MHPHHPDM_01051 1.7e-72 S SnoaL-like domain
MHPHHPDM_01052 2.8e-241 M Glycosyltransferase, group 2 family protein
MHPHHPDM_01053 5.1e-209 mccF V LD-carboxypeptidase
MHPHHPDM_01054 1.4e-78 K Acetyltransferase (GNAT) domain
MHPHHPDM_01055 1e-106
MHPHHPDM_01056 1.4e-117 S Domain of unknown function (DUF4811)
MHPHHPDM_01057 7e-270 lmrB EGP Major facilitator Superfamily
MHPHHPDM_01058 1.7e-84 merR K MerR HTH family regulatory protein
MHPHHPDM_01059 2.6e-58
MHPHHPDM_01060 2e-120 sirR K iron dependent repressor
MHPHHPDM_01061 6e-31 cspC K Cold shock protein
MHPHHPDM_01062 1.5e-130 thrE S Putative threonine/serine exporter
MHPHHPDM_01063 2.2e-76 S Threonine/Serine exporter, ThrE
MHPHHPDM_01064 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MHPHHPDM_01065 3.9e-119 lssY 3.6.1.27 I phosphatase
MHPHHPDM_01066 2e-154 I alpha/beta hydrolase fold
MHPHHPDM_01067 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
MHPHHPDM_01068 3.6e-91 K Transcriptional regulator
MHPHHPDM_01069 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MHPHHPDM_01070 1.6e-263 lysP E amino acid
MHPHHPDM_01071 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MHPHHPDM_01072 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MHPHHPDM_01073 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHPHHPDM_01080 6.9e-78 ctsR K Belongs to the CtsR family
MHPHHPDM_01081 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MHPHHPDM_01082 1.5e-109 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01083 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPHHPDM_01084 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPHHPDM_01085 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MHPHHPDM_01086 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MHPHHPDM_01087 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MHPHHPDM_01088 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MHPHHPDM_01089 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MHPHHPDM_01090 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MHPHHPDM_01091 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MHPHHPDM_01092 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MHPHHPDM_01093 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MHPHHPDM_01094 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MHPHHPDM_01095 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MHPHHPDM_01096 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MHPHHPDM_01097 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MHPHHPDM_01098 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MHPHHPDM_01099 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MHPHHPDM_01100 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MHPHHPDM_01101 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MHPHHPDM_01102 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MHPHHPDM_01103 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MHPHHPDM_01104 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MHPHHPDM_01105 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MHPHHPDM_01106 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MHPHHPDM_01107 2.2e-24 rpmD J Ribosomal protein L30
MHPHHPDM_01108 6.3e-70 rplO J Binds to the 23S rRNA
MHPHHPDM_01109 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MHPHHPDM_01110 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MHPHHPDM_01111 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MHPHHPDM_01112 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MHPHHPDM_01113 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MHPHHPDM_01114 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MHPHHPDM_01115 2.1e-61 rplQ J Ribosomal protein L17
MHPHHPDM_01116 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHPHHPDM_01117 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
MHPHHPDM_01118 7.2e-86 ynhH S NusG domain II
MHPHHPDM_01119 0.0 ndh 1.6.99.3 C NADH dehydrogenase
MHPHHPDM_01120 3.5e-142 cad S FMN_bind
MHPHHPDM_01121 4.4e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHPHHPDM_01122 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPHHPDM_01123 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPHHPDM_01124 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MHPHHPDM_01125 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MHPHHPDM_01126 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MHPHHPDM_01127 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MHPHHPDM_01128 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
MHPHHPDM_01129 2.2e-173 ywhK S Membrane
MHPHHPDM_01130 5.5e-30 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHPHHPDM_01131 1.5e-163 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHPHHPDM_01132 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHPHHPDM_01133 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHPHHPDM_01134 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
MHPHHPDM_01135 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MHPHHPDM_01137 2.2e-221 P Sodium:sulfate symporter transmembrane region
MHPHHPDM_01138 4.1e-53 yitW S Iron-sulfur cluster assembly protein
MHPHHPDM_01139 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
MHPHHPDM_01140 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
MHPHHPDM_01141 7.2e-197 K Helix-turn-helix domain
MHPHHPDM_01142 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MHPHHPDM_01143 4.5e-132 mntB 3.6.3.35 P ABC transporter
MHPHHPDM_01144 8.2e-141 mtsB U ABC 3 transport family
MHPHHPDM_01145 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
MHPHHPDM_01146 3.1e-50
MHPHHPDM_01147 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MHPHHPDM_01148 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
MHPHHPDM_01149 2.9e-179 citR K sugar-binding domain protein
MHPHHPDM_01150 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MHPHHPDM_01151 1.7e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MHPHHPDM_01152 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
MHPHHPDM_01153 9.7e-161 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MHPHHPDM_01154 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MHPHHPDM_01155 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MHPHHPDM_01156 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MHPHHPDM_01157 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MHPHHPDM_01158 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MHPHHPDM_01159 5.1e-190 phnD P Phosphonate ABC transporter
MHPHHPDM_01160 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MHPHHPDM_01161 2.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
MHPHHPDM_01162 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
MHPHHPDM_01163 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
MHPHHPDM_01164 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MHPHHPDM_01165 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHPHHPDM_01166 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
MHPHHPDM_01167 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MHPHHPDM_01168 1e-57 yabA L Involved in initiation control of chromosome replication
MHPHHPDM_01169 3.3e-186 holB 2.7.7.7 L DNA polymerase III
MHPHHPDM_01170 2.4e-53 yaaQ S Cyclic-di-AMP receptor
MHPHHPDM_01171 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MHPHHPDM_01172 2.2e-38 yaaL S Protein of unknown function (DUF2508)
MHPHHPDM_01173 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MHPHHPDM_01174 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MHPHHPDM_01175 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MHPHHPDM_01176 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MHPHHPDM_01177 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
MHPHHPDM_01178 6.5e-37 nrdH O Glutaredoxin
MHPHHPDM_01179 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPHHPDM_01180 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MHPHHPDM_01181 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
MHPHHPDM_01182 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHPHHPDM_01183 1.2e-38 L nuclease
MHPHHPDM_01184 9.3e-178 F DNA/RNA non-specific endonuclease
MHPHHPDM_01185 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MHPHHPDM_01186 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MHPHHPDM_01187 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MHPHHPDM_01188 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MHPHHPDM_01189 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01190 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
MHPHHPDM_01191 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MHPHHPDM_01192 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MHPHHPDM_01193 2.4e-101 sigH K Sigma-70 region 2
MHPHHPDM_01194 7.7e-97 yacP S YacP-like NYN domain
MHPHHPDM_01195 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MHPHHPDM_01196 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MHPHHPDM_01197 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPHHPDM_01198 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MHPHHPDM_01199 3.7e-205 yacL S domain protein
MHPHHPDM_01200 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MHPHHPDM_01201 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MHPHHPDM_01202 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
MHPHHPDM_01203 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MHPHHPDM_01204 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
MHPHHPDM_01205 5.2e-113 zmp2 O Zinc-dependent metalloprotease
MHPHHPDM_01206 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHPHHPDM_01207 8.3e-177 EG EamA-like transporter family
MHPHHPDM_01208 5.6e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MHPHHPDM_01209 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MHPHHPDM_01210 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MHPHHPDM_01211 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MHPHHPDM_01212 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
MHPHHPDM_01213 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
MHPHHPDM_01214 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MHPHHPDM_01215 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
MHPHHPDM_01216 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
MHPHHPDM_01217 0.0 levR K Sigma-54 interaction domain
MHPHHPDM_01218 4.7e-64 S Domain of unknown function (DUF956)
MHPHHPDM_01219 4.4e-169 manN G system, mannose fructose sorbose family IID component
MHPHHPDM_01220 3.4e-133 manY G PTS system
MHPHHPDM_01221 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MHPHHPDM_01222 7.4e-152 G Peptidase_C39 like family
MHPHHPDM_01224 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MHPHHPDM_01225 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MHPHHPDM_01226 3.7e-81 ydcK S Belongs to the SprT family
MHPHHPDM_01227 0.0 yhgF K Tex-like protein N-terminal domain protein
MHPHHPDM_01228 3.4e-71
MHPHHPDM_01229 0.0 pacL 3.6.3.8 P P-type ATPase
MHPHHPDM_01230 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MHPHHPDM_01231 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MHPHHPDM_01232 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MHPHHPDM_01233 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
MHPHHPDM_01234 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MHPHHPDM_01235 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MHPHHPDM_01236 1.6e-151 pnuC H nicotinamide mononucleotide transporter
MHPHHPDM_01237 4.7e-194 ybiR P Citrate transporter
MHPHHPDM_01238 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MHPHHPDM_01239 2.5e-53 S Cupin domain
MHPHHPDM_01240 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
MHPHHPDM_01244 1.3e-150 yjjH S Calcineurin-like phosphoesterase
MHPHHPDM_01245 3e-252 dtpT U amino acid peptide transporter
MHPHHPDM_01247 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHPHHPDM_01248 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
MHPHHPDM_01249 1.1e-225 patA 2.6.1.1 E Aminotransferase
MHPHHPDM_01250 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHPHHPDM_01251 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MHPHHPDM_01252 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
MHPHHPDM_01253 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MHPHHPDM_01254 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MHPHHPDM_01255 2.7e-39 ptsH G phosphocarrier protein HPR
MHPHHPDM_01256 6.5e-30
MHPHHPDM_01257 0.0 clpE O Belongs to the ClpA ClpB family
MHPHHPDM_01258 2.2e-73 L Integrase
MHPHHPDM_01259 1e-63 K Winged helix DNA-binding domain
MHPHHPDM_01260 1.8e-181 oppF P Belongs to the ABC transporter superfamily
MHPHHPDM_01261 9.2e-203 oppD P Belongs to the ABC transporter superfamily
MHPHHPDM_01262 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPHHPDM_01263 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MHPHHPDM_01264 1.3e-309 oppA E ABC transporter, substratebinding protein
MHPHHPDM_01265 3.2e-57 ywjH S Protein of unknown function (DUF1634)
MHPHHPDM_01266 5.5e-126 yxaA S membrane transporter protein
MHPHHPDM_01267 7.1e-161 lysR5 K LysR substrate binding domain
MHPHHPDM_01268 2.7e-196 M MucBP domain
MHPHHPDM_01269 1.7e-273
MHPHHPDM_01270 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MHPHHPDM_01271 2.4e-253 gor 1.8.1.7 C Glutathione reductase
MHPHHPDM_01272 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
MHPHHPDM_01273 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MHPHHPDM_01274 9.5e-213 gntP EG Gluconate
MHPHHPDM_01275 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MHPHHPDM_01276 9.3e-188 yueF S AI-2E family transporter
MHPHHPDM_01277 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MHPHHPDM_01278 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
MHPHHPDM_01279 7.8e-48 K sequence-specific DNA binding
MHPHHPDM_01280 2.5e-133 cwlO M NlpC/P60 family
MHPHHPDM_01281 4.1e-106 ygaC J Belongs to the UPF0374 family
MHPHHPDM_01282 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
MHPHHPDM_01283 3e-125
MHPHHPDM_01284 6.8e-101 K DNA-templated transcription, initiation
MHPHHPDM_01285 1.3e-25
MHPHHPDM_01286 7e-30
MHPHHPDM_01287 7.3e-33 S Protein of unknown function (DUF2922)
MHPHHPDM_01288 3.8e-53
MHPHHPDM_01289 2.2e-17 L Helix-turn-helix domain
MHPHHPDM_01290 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_01291 1.4e-154 yihY S Belongs to the UPF0761 family
MHPHHPDM_01292 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MHPHHPDM_01293 1.2e-219 pbpX1 V Beta-lactamase
MHPHHPDM_01294 8.4e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MHPHHPDM_01295 1.4e-106
MHPHHPDM_01296 1.3e-73
MHPHHPDM_01298 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01299 2.9e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_01300 2.3e-75 T Universal stress protein family
MHPHHPDM_01302 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
MHPHHPDM_01303 2.4e-189 mocA S Oxidoreductase
MHPHHPDM_01304 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
MHPHHPDM_01305 1.1e-62 S Domain of unknown function (DUF4828)
MHPHHPDM_01306 2e-143 lys M Glycosyl hydrolases family 25
MHPHHPDM_01307 2.3e-151 gntR K rpiR family
MHPHHPDM_01308 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01309 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_01310 0.0 yfgQ P E1-E2 ATPase
MHPHHPDM_01311 6e-100 yobS K Bacterial regulatory proteins, tetR family
MHPHHPDM_01312 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPHHPDM_01313 1e-190 yegS 2.7.1.107 G Lipid kinase
MHPHHPDM_01314 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPHHPDM_01315 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MHPHHPDM_01316 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MHPHHPDM_01317 2.6e-198 camS S sex pheromone
MHPHHPDM_01318 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHPHHPDM_01319 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MHPHHPDM_01320 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MHPHHPDM_01321 1e-93 S UPF0316 protein
MHPHHPDM_01322 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MHPHHPDM_01323 3.4e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
MHPHHPDM_01324 7.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
MHPHHPDM_01325 1.7e-63 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_01326 6.2e-50
MHPHHPDM_01327 4.3e-78
MHPHHPDM_01328 8.9e-23 L hmm pf00665
MHPHHPDM_01329 6.9e-29 L hmm pf00665
MHPHHPDM_01330 7.6e-46 L Helix-turn-helix domain
MHPHHPDM_01332 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
MHPHHPDM_01334 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MHPHHPDM_01335 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MHPHHPDM_01336 2.5e-164 fabK 1.3.1.9 S Nitronate monooxygenase
MHPHHPDM_01337 0.0 helD 3.6.4.12 L DNA helicase
MHPHHPDM_01338 7.2e-110 dedA S SNARE associated Golgi protein
MHPHHPDM_01339 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
MHPHHPDM_01340 0.0 yjbQ P TrkA C-terminal domain protein
MHPHHPDM_01341 4.7e-125 pgm3 G Phosphoglycerate mutase family
MHPHHPDM_01342 5.5e-129 pgm3 G Phosphoglycerate mutase family
MHPHHPDM_01343 1.2e-26
MHPHHPDM_01344 1.3e-48 sugE U Multidrug resistance protein
MHPHHPDM_01345 2.9e-78 3.6.1.55 F NUDIX domain
MHPHHPDM_01346 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MHPHHPDM_01347 7.1e-98 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01348 3.8e-85 S membrane transporter protein
MHPHHPDM_01349 4.9e-210 EGP Major facilitator Superfamily
MHPHHPDM_01350 2.8e-70 K MarR family
MHPHHPDM_01351 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
MHPHHPDM_01352 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_01353 1.4e-245 steT E amino acid
MHPHHPDM_01354 6.1e-140 G YdjC-like protein
MHPHHPDM_01355 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MHPHHPDM_01356 1.4e-153 K CAT RNA binding domain
MHPHHPDM_01357 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHPHHPDM_01358 4e-108 glnP P ABC transporter permease
MHPHHPDM_01359 1.6e-109 gluC P ABC transporter permease
MHPHHPDM_01360 7.8e-149 glnH ET ABC transporter substrate-binding protein
MHPHHPDM_01361 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_01363 3.6e-41
MHPHHPDM_01364 9.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPHHPDM_01365 3.2e-184 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MHPHHPDM_01366 1.7e-73 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MHPHHPDM_01367 4.9e-148
MHPHHPDM_01368 7.1e-12 3.2.1.14 GH18
MHPHHPDM_01369 1.3e-81 zur P Belongs to the Fur family
MHPHHPDM_01370 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
MHPHHPDM_01371 1.8e-19
MHPHHPDM_01372 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MHPHHPDM_01373 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MHPHHPDM_01374 2.5e-88
MHPHHPDM_01375 1.1e-251 yfnA E Amino Acid
MHPHHPDM_01376 2.6e-46
MHPHHPDM_01377 1.1e-68 O OsmC-like protein
MHPHHPDM_01378 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MHPHHPDM_01379 0.0 oatA I Acyltransferase
MHPHHPDM_01380 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHPHHPDM_01381 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MHPHHPDM_01382 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPHHPDM_01383 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MHPHHPDM_01384 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPHHPDM_01385 1.2e-225 pbuG S permease
MHPHHPDM_01386 1.5e-19
MHPHHPDM_01387 1.2e-82 K Transcriptional regulator
MHPHHPDM_01388 2.5e-152 licD M LicD family
MHPHHPDM_01389 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MHPHHPDM_01390 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MHPHHPDM_01391 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MHPHHPDM_01392 3.6e-242 EGP Major facilitator Superfamily
MHPHHPDM_01393 2.5e-89 V VanZ like family
MHPHHPDM_01394 1.5e-33
MHPHHPDM_01395 1.9e-71 spxA 1.20.4.1 P ArsC family
MHPHHPDM_01397 2.1e-143
MHPHHPDM_01398 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHPHHPDM_01399 8.8e-154 G Transmembrane secretion effector
MHPHHPDM_01400 3e-131 1.5.1.39 C nitroreductase
MHPHHPDM_01401 3e-72
MHPHHPDM_01402 1.5e-52
MHPHHPDM_01403 1.2e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MHPHHPDM_01404 3.1e-104 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01405 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MHPHHPDM_01406 4.5e-123 yliE T EAL domain
MHPHHPDM_01411 5.1e-08
MHPHHPDM_01417 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
MHPHHPDM_01418 8.9e-182 P secondary active sulfate transmembrane transporter activity
MHPHHPDM_01419 1.4e-95
MHPHHPDM_01420 2e-94 K Acetyltransferase (GNAT) domain
MHPHHPDM_01421 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
MHPHHPDM_01422 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
MHPHHPDM_01424 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
MHPHHPDM_01425 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MHPHHPDM_01426 9.2e-256 mmuP E amino acid
MHPHHPDM_01427 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MHPHHPDM_01428 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_01429 1.6e-121
MHPHHPDM_01430 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MHPHHPDM_01431 5.5e-278 bmr3 EGP Major facilitator Superfamily
MHPHHPDM_01432 1.7e-18 N Cell shape-determining protein MreB
MHPHHPDM_01433 2.1e-139 N Cell shape-determining protein MreB
MHPHHPDM_01434 0.0 S Pfam Methyltransferase
MHPHHPDM_01435 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_01436 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_01437 4.2e-29
MHPHHPDM_01438 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
MHPHHPDM_01439 1.4e-124 3.6.1.27 I Acid phosphatase homologues
MHPHHPDM_01440 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPHHPDM_01441 3e-301 ytgP S Polysaccharide biosynthesis protein
MHPHHPDM_01442 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MHPHHPDM_01443 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MHPHHPDM_01444 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
MHPHHPDM_01445 4.1e-84 uspA T Belongs to the universal stress protein A family
MHPHHPDM_01446 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
MHPHHPDM_01447 5.2e-173 ugpA U Binding-protein-dependent transport system inner membrane component
MHPHHPDM_01448 1.1e-150 ugpE G ABC transporter permease
MHPHHPDM_01449 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
MHPHHPDM_01450 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
MHPHHPDM_01451 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MHPHHPDM_01452 3.9e-179 XK27_06930 V domain protein
MHPHHPDM_01454 2.6e-124 V Transport permease protein
MHPHHPDM_01455 2.3e-156 V ABC transporter
MHPHHPDM_01456 4e-176 K LytTr DNA-binding domain
MHPHHPDM_01458 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MHPHHPDM_01459 1.6e-64 K helix_turn_helix, mercury resistance
MHPHHPDM_01460 3.5e-117 GM NAD(P)H-binding
MHPHHPDM_01461 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MHPHHPDM_01462 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
MHPHHPDM_01463 1.7e-108
MHPHHPDM_01464 2.5e-223 pltK 2.7.13.3 T GHKL domain
MHPHHPDM_01465 1.6e-137 pltR K LytTr DNA-binding domain
MHPHHPDM_01466 4.5e-55
MHPHHPDM_01467 2.5e-59
MHPHHPDM_01468 1.9e-113 S CAAX protease self-immunity
MHPHHPDM_01469 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_01470 1e-90
MHPHHPDM_01471 2.5e-46
MHPHHPDM_01472 0.0 uvrA2 L ABC transporter
MHPHHPDM_01475 5.9e-52
MHPHHPDM_01476 3.5e-10
MHPHHPDM_01477 2.1e-180
MHPHHPDM_01478 1.9e-89 gtcA S Teichoic acid glycosylation protein
MHPHHPDM_01479 3.6e-58 S Protein of unknown function (DUF1516)
MHPHHPDM_01480 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MHPHHPDM_01481 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MHPHHPDM_01482 1.2e-307 S Protein conserved in bacteria
MHPHHPDM_01483 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MHPHHPDM_01484 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
MHPHHPDM_01485 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
MHPHHPDM_01486 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
MHPHHPDM_01487 0.0 yfbS P Sodium:sulfate symporter transmembrane region
MHPHHPDM_01488 4.5e-121 S CAAX protease self-immunity
MHPHHPDM_01489 2.5e-114 V CAAX protease self-immunity
MHPHHPDM_01490 7.1e-121 yclH V ABC transporter
MHPHHPDM_01491 1.8e-185 yclI V MacB-like periplasmic core domain
MHPHHPDM_01492 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MHPHHPDM_01493 1.1e-106 tag 3.2.2.20 L glycosylase
MHPHHPDM_01494 0.0 ydgH S MMPL family
MHPHHPDM_01495 3.1e-104 K transcriptional regulator
MHPHHPDM_01496 2.7e-123 2.7.6.5 S RelA SpoT domain protein
MHPHHPDM_01497 1.3e-47
MHPHHPDM_01498 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
MHPHHPDM_01499 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MHPHHPDM_01500 2.1e-41
MHPHHPDM_01501 3.2e-55
MHPHHPDM_01502 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_01503 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
MHPHHPDM_01504 4.1e-49
MHPHHPDM_01505 7e-127 K Transcriptional regulatory protein, C terminal
MHPHHPDM_01506 9.8e-250 T PhoQ Sensor
MHPHHPDM_01507 3.3e-65 K helix_turn_helix, mercury resistance
MHPHHPDM_01508 1.1e-251 ydiC1 EGP Major facilitator Superfamily
MHPHHPDM_01509 1.4e-40
MHPHHPDM_01510 5.9e-38
MHPHHPDM_01511 5.1e-116
MHPHHPDM_01512 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MHPHHPDM_01513 3.7e-120 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01514 1.8e-72 K Transcriptional regulator
MHPHHPDM_01515 3.5e-70
MHPHHPDM_01516 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MHPHHPDM_01517 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MHPHHPDM_01518 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
MHPHHPDM_01519 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MHPHHPDM_01520 1.4e-144
MHPHHPDM_01521 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MHPHHPDM_01522 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MHPHHPDM_01523 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MHPHHPDM_01524 3.5e-129 treR K UTRA
MHPHHPDM_01525 2.9e-42
MHPHHPDM_01526 7.3e-43 S Protein of unknown function (DUF2089)
MHPHHPDM_01527 4.3e-141 pnuC H nicotinamide mononucleotide transporter
MHPHHPDM_01528 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
MHPHHPDM_01529 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MHPHHPDM_01530 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MHPHHPDM_01531 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MHPHHPDM_01532 3.5e-97 yieF S NADPH-dependent FMN reductase
MHPHHPDM_01533 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
MHPHHPDM_01534 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
MHPHHPDM_01535 7.7e-62
MHPHHPDM_01536 6.2e-94
MHPHHPDM_01537 1.2e-49
MHPHHPDM_01538 6.2e-57 trxA1 O Belongs to the thioredoxin family
MHPHHPDM_01539 2.1e-73
MHPHHPDM_01540 8.1e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MHPHHPDM_01541 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_01542 0.0 mtlR K Mga helix-turn-helix domain
MHPHHPDM_01543 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_01544 7.4e-277 pipD E Dipeptidase
MHPHHPDM_01545 4.8e-99 K Helix-turn-helix domain
MHPHHPDM_01546 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
MHPHHPDM_01547 2.2e-173 P Major Facilitator Superfamily
MHPHHPDM_01548 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MHPHHPDM_01549 4.7e-31 ygzD K Transcriptional
MHPHHPDM_01550 1e-69
MHPHHPDM_01551 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MHPHHPDM_01552 1.4e-158 dkgB S reductase
MHPHHPDM_01553 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MHPHHPDM_01554 3.1e-101 S ABC transporter permease
MHPHHPDM_01555 2e-258 P ABC transporter
MHPHHPDM_01556 3.1e-116 P cobalt transport
MHPHHPDM_01557 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
MHPHHPDM_01558 6.8e-24
MHPHHPDM_01559 0.0 macB3 V ABC transporter, ATP-binding protein
MHPHHPDM_01560 2e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_01561 2e-61 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_01562 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
MHPHHPDM_01563 1.6e-16
MHPHHPDM_01564 4.7e-16
MHPHHPDM_01565 1.5e-14
MHPHHPDM_01566 2.8e-167 M MucBP domain
MHPHHPDM_01567 0.0 bztC D nuclear chromosome segregation
MHPHHPDM_01568 7.3e-83 K MarR family
MHPHHPDM_01569 1.4e-43
MHPHHPDM_01570 2e-38
MHPHHPDM_01571 6.4e-226 sip L Belongs to the 'phage' integrase family
MHPHHPDM_01575 1.6e-29
MHPHHPDM_01576 4.1e-147 L DNA replication protein
MHPHHPDM_01577 7.9e-263 S Virulence-associated protein E
MHPHHPDM_01578 7e-74
MHPHHPDM_01580 4.6e-47 S head-tail joining protein
MHPHHPDM_01581 1.6e-67 L Phage-associated protein
MHPHHPDM_01582 2.5e-83 terS L Phage terminase, small subunit
MHPHHPDM_01583 0.0 terL S overlaps another CDS with the same product name
MHPHHPDM_01585 1.1e-203 S Phage portal protein
MHPHHPDM_01586 7.2e-278 S Caudovirus prohead serine protease
MHPHHPDM_01587 1.1e-35 S Phage gp6-like head-tail connector protein
MHPHHPDM_01588 3.6e-61
MHPHHPDM_01590 8.9e-30
MHPHHPDM_01592 7.3e-219 int L Belongs to the 'phage' integrase family
MHPHHPDM_01596 4.1e-13 S DNA/RNA non-specific endonuclease
MHPHHPDM_01598 8.4e-37
MHPHHPDM_01599 3.3e-76 E IrrE N-terminal-like domain
MHPHHPDM_01600 4.5e-61 yvaO K Helix-turn-helix domain
MHPHHPDM_01601 1.3e-37 K Helix-turn-helix
MHPHHPDM_01603 4.5e-54
MHPHHPDM_01604 2.8e-85
MHPHHPDM_01606 1.6e-54 S Bacteriophage Mu Gam like protein
MHPHHPDM_01607 1.4e-64
MHPHHPDM_01608 2.5e-161 L DnaD domain protein
MHPHHPDM_01609 2.2e-50
MHPHHPDM_01610 4.9e-63 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MHPHHPDM_01612 2.4e-13 S YopX protein
MHPHHPDM_01613 4.1e-14
MHPHHPDM_01617 1.3e-79 K acetyltransferase
MHPHHPDM_01618 6.6e-31 rplV S ASCH
MHPHHPDM_01619 2.2e-17
MHPHHPDM_01621 3.5e-11
MHPHHPDM_01622 2e-75 ps333 L Terminase small subunit
MHPHHPDM_01624 8.7e-248 S Phage terminase, large subunit
MHPHHPDM_01625 7.6e-305 S Phage portal protein, SPP1 Gp6-like
MHPHHPDM_01626 2.9e-168 S Phage Mu protein F like protein
MHPHHPDM_01627 8.6e-71 S Domain of unknown function (DUF4355)
MHPHHPDM_01628 1.5e-194 gpG
MHPHHPDM_01629 1.5e-56 S Phage gp6-like head-tail connector protein
MHPHHPDM_01630 1.7e-50
MHPHHPDM_01631 3.6e-94
MHPHHPDM_01632 4.1e-61
MHPHHPDM_01633 6.7e-96
MHPHHPDM_01634 4.3e-83 S Phage tail assembly chaperone protein, TAC
MHPHHPDM_01636 0.0 D NLP P60 protein
MHPHHPDM_01637 8.1e-134 S phage tail
MHPHHPDM_01638 1e-289 M Prophage endopeptidase tail
MHPHHPDM_01639 1.2e-172 E GDSL-like Lipase/Acylhydrolase family
MHPHHPDM_01640 3.3e-96 S Domain of unknown function (DUF2479)
MHPHHPDM_01641 2.6e-15 S Domain of unknown function (DUF2479)
MHPHHPDM_01644 1e-87
MHPHHPDM_01645 5.9e-21
MHPHHPDM_01647 7.6e-170 lys M Glycosyl hydrolases family 25
MHPHHPDM_01648 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MHPHHPDM_01649 1.6e-140 S Belongs to the UPF0246 family
MHPHHPDM_01650 6e-76
MHPHHPDM_01651 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MHPHHPDM_01652 7e-141
MHPHHPDM_01654 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MHPHHPDM_01655 4.8e-40
MHPHHPDM_01656 7.8e-129 cbiO P ABC transporter
MHPHHPDM_01657 2.6e-149 P Cobalt transport protein
MHPHHPDM_01658 4.8e-182 nikMN P PDGLE domain
MHPHHPDM_01659 2.1e-120 K Crp-like helix-turn-helix domain
MHPHHPDM_01660 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
MHPHHPDM_01661 5.9e-124 larB S AIR carboxylase
MHPHHPDM_01662 8.5e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MHPHHPDM_01663 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_01664 6.3e-151 larE S NAD synthase
MHPHHPDM_01665 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
MHPHHPDM_01666 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MHPHHPDM_01667 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MHPHHPDM_01668 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MHPHHPDM_01669 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MHPHHPDM_01670 4.3e-135 S peptidase C26
MHPHHPDM_01671 9.8e-302 L HIRAN domain
MHPHHPDM_01672 3.4e-85 F NUDIX domain
MHPHHPDM_01673 2.6e-250 yifK E Amino acid permease
MHPHHPDM_01674 5.2e-122
MHPHHPDM_01675 3.3e-149 ydjP I Alpha/beta hydrolase family
MHPHHPDM_01676 0.0 pacL1 P P-type ATPase
MHPHHPDM_01677 2.9e-142 2.4.2.3 F Phosphorylase superfamily
MHPHHPDM_01678 1.6e-28 KT PspC domain
MHPHHPDM_01679 3.6e-111 S NADPH-dependent FMN reductase
MHPHHPDM_01680 1.2e-74 papX3 K Transcriptional regulator
MHPHHPDM_01681 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
MHPHHPDM_01682 5.8e-82 S Protein of unknown function (DUF3021)
MHPHHPDM_01683 4.7e-227 mdtG EGP Major facilitator Superfamily
MHPHHPDM_01684 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_01685 8.1e-216 yeaN P Transporter, major facilitator family protein
MHPHHPDM_01687 3.4e-160 S reductase
MHPHHPDM_01688 1.2e-165 1.1.1.65 C Aldo keto reductase
MHPHHPDM_01689 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MHPHHPDM_01690 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MHPHHPDM_01691 7.8e-49
MHPHHPDM_01692 2.2e-258
MHPHHPDM_01693 4e-209 C Oxidoreductase
MHPHHPDM_01694 4.9e-151 cbiQ P cobalt transport
MHPHHPDM_01695 0.0 ykoD P ABC transporter, ATP-binding protein
MHPHHPDM_01696 2.5e-98 S UPF0397 protein
MHPHHPDM_01698 1.6e-129 K UbiC transcription regulator-associated domain protein
MHPHHPDM_01699 8.3e-54 K Transcriptional regulator PadR-like family
MHPHHPDM_01700 3e-134
MHPHHPDM_01701 5.8e-149
MHPHHPDM_01702 9.1e-89
MHPHHPDM_01703 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MHPHHPDM_01704 2e-169 yjjC V ABC transporter
MHPHHPDM_01705 4.3e-297 M Exporter of polyketide antibiotics
MHPHHPDM_01706 1.1e-116 K Transcriptional regulator
MHPHHPDM_01707 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
MHPHHPDM_01708 9.5e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
MHPHHPDM_01710 1.9e-92 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01711 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MHPHHPDM_01712 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MHPHHPDM_01713 5.5e-101 dhaL 2.7.1.121 S Dak2
MHPHHPDM_01714 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
MHPHHPDM_01715 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_01716 1e-190 malR K Transcriptional regulator, LacI family
MHPHHPDM_01717 2e-180 yvdE K helix_turn _helix lactose operon repressor
MHPHHPDM_01718 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MHPHHPDM_01719 2.9e-148 yxeH S hydrolase
MHPHHPDM_01720 9e-264 ywfO S HD domain protein
MHPHHPDM_01721 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MHPHHPDM_01722 3.8e-78 ywiB S Domain of unknown function (DUF1934)
MHPHHPDM_01723 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MHPHHPDM_01724 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MHPHHPDM_01725 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MHPHHPDM_01726 3.1e-229 tdcC E amino acid
MHPHHPDM_01727 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MHPHHPDM_01728 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MHPHHPDM_01729 6.4e-131 S YheO-like PAS domain
MHPHHPDM_01730 2.5e-26
MHPHHPDM_01731 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MHPHHPDM_01732 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MHPHHPDM_01733 7.8e-41 rpmE2 J Ribosomal protein L31
MHPHHPDM_01734 3.2e-214 J translation release factor activity
MHPHHPDM_01735 9.2e-127 srtA 3.4.22.70 M sortase family
MHPHHPDM_01736 1.7e-91 lemA S LemA family
MHPHHPDM_01737 4.6e-139 htpX O Belongs to the peptidase M48B family
MHPHHPDM_01738 2e-146
MHPHHPDM_01739 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MHPHHPDM_01740 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MHPHHPDM_01741 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MHPHHPDM_01742 9.3e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MHPHHPDM_01743 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
MHPHHPDM_01744 0.0 kup P Transport of potassium into the cell
MHPHHPDM_01745 2.9e-193 P ABC transporter, substratebinding protein
MHPHHPDM_01746 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
MHPHHPDM_01747 1.9e-133 P ATPases associated with a variety of cellular activities
MHPHHPDM_01748 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MHPHHPDM_01749 8.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MHPHHPDM_01750 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MHPHHPDM_01751 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MHPHHPDM_01752 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
MHPHHPDM_01753 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
MHPHHPDM_01754 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MHPHHPDM_01755 4.1e-84 S QueT transporter
MHPHHPDM_01756 6.2e-114 S (CBS) domain
MHPHHPDM_01757 4.2e-264 S Putative peptidoglycan binding domain
MHPHHPDM_01758 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MHPHHPDM_01759 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MHPHHPDM_01760 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MHPHHPDM_01761 4.3e-289 yabM S Polysaccharide biosynthesis protein
MHPHHPDM_01762 2.2e-42 yabO J S4 domain protein
MHPHHPDM_01764 1.1e-63 divIC D Septum formation initiator
MHPHHPDM_01765 3.1e-74 yabR J RNA binding
MHPHHPDM_01766 6.4e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MHPHHPDM_01767 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MHPHHPDM_01768 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MHPHHPDM_01769 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MHPHHPDM_01770 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPHHPDM_01771 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MHPHHPDM_01772 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
MHPHHPDM_01773 0.0 cadA P P-type ATPase
MHPHHPDM_01775 1.8e-124 yyaQ S YjbR
MHPHHPDM_01776 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
MHPHHPDM_01777 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
MHPHHPDM_01778 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MHPHHPDM_01779 2.2e-199 frlB M SIS domain
MHPHHPDM_01780 3e-26 3.2.2.10 S Belongs to the LOG family
MHPHHPDM_01781 3.4e-253 nhaC C Na H antiporter NhaC
MHPHHPDM_01782 1.3e-249 cycA E Amino acid permease
MHPHHPDM_01783 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01784 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01785 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MHPHHPDM_01786 7.7e-160 azoB GM NmrA-like family
MHPHHPDM_01787 5.4e-66 K Winged helix DNA-binding domain
MHPHHPDM_01788 7e-71 spx4 1.20.4.1 P ArsC family
MHPHHPDM_01789 1.7e-66 yeaO S Protein of unknown function, DUF488
MHPHHPDM_01790 4e-53
MHPHHPDM_01791 4.1e-214 mutY L A G-specific adenine glycosylase
MHPHHPDM_01792 1.9e-62
MHPHHPDM_01793 4.3e-86
MHPHHPDM_01794 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
MHPHHPDM_01795 5.9e-55
MHPHHPDM_01796 2.1e-14
MHPHHPDM_01797 1.1e-115 GM NmrA-like family
MHPHHPDM_01798 1.3e-81 elaA S GNAT family
MHPHHPDM_01799 5.9e-158 EG EamA-like transporter family
MHPHHPDM_01800 1.8e-119 S membrane
MHPHHPDM_01801 6.8e-111 S VIT family
MHPHHPDM_01802 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MHPHHPDM_01803 0.0 copB 3.6.3.4 P P-type ATPase
MHPHHPDM_01804 4.7e-73 copR K Copper transport repressor CopY TcrY
MHPHHPDM_01805 7.4e-40
MHPHHPDM_01806 7.7e-73 S COG NOG18757 non supervised orthologous group
MHPHHPDM_01807 1.5e-248 lmrB EGP Major facilitator Superfamily
MHPHHPDM_01808 3.4e-25
MHPHHPDM_01809 4.2e-49
MHPHHPDM_01810 1.6e-64 ycgX S Protein of unknown function (DUF1398)
MHPHHPDM_01811 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MHPHHPDM_01812 5.9e-214 mdtG EGP Major facilitator Superfamily
MHPHHPDM_01813 2.6e-180 D Alpha beta
MHPHHPDM_01814 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
MHPHHPDM_01815 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MHPHHPDM_01816 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
MHPHHPDM_01817 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MHPHHPDM_01818 8.4e-152 ywkB S Membrane transport protein
MHPHHPDM_01819 5.2e-164 yvgN C Aldo keto reductase
MHPHHPDM_01820 9.2e-133 thrE S Putative threonine/serine exporter
MHPHHPDM_01821 7.5e-77 S Threonine/Serine exporter, ThrE
MHPHHPDM_01822 2.3e-43 S Protein of unknown function (DUF1093)
MHPHHPDM_01823 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MHPHHPDM_01824 2.7e-91 ymdB S Macro domain protein
MHPHHPDM_01825 1.2e-95 K transcriptional regulator
MHPHHPDM_01826 5.5e-50 yvlA
MHPHHPDM_01827 6e-161 ypuA S Protein of unknown function (DUF1002)
MHPHHPDM_01828 0.0
MHPHHPDM_01829 1.7e-121 S Bacterial protein of unknown function (DUF916)
MHPHHPDM_01830 1.1e-161 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MHPHHPDM_01831 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MHPHHPDM_01832 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MHPHHPDM_01833 1.6e-180 galR K Transcriptional regulator
MHPHHPDM_01834 8e-76 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_01835 2.4e-22 fic D Fic/DOC family
MHPHHPDM_01836 1.9e-25 fic D Fic/DOC family
MHPHHPDM_01837 2.1e-38 fic D Fic/DOC family
MHPHHPDM_01838 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
MHPHHPDM_01839 2.5e-231 EGP Major facilitator Superfamily
MHPHHPDM_01840 2.1e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MHPHHPDM_01841 2.3e-229 mdtH P Sugar (and other) transporter
MHPHHPDM_01842 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MHPHHPDM_01843 1.4e-248 brnQ U Component of the transport system for branched-chain amino acids
MHPHHPDM_01844 0.0 ubiB S ABC1 family
MHPHHPDM_01845 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_01846 3.9e-218 3.1.3.1 S associated with various cellular activities
MHPHHPDM_01847 1.4e-248 S Putative metallopeptidase domain
MHPHHPDM_01848 1.5e-49
MHPHHPDM_01849 7.7e-103 K Bacterial regulatory proteins, tetR family
MHPHHPDM_01850 4.6e-45
MHPHHPDM_01851 2.3e-99 S WxL domain surface cell wall-binding
MHPHHPDM_01852 1.5e-118 S WxL domain surface cell wall-binding
MHPHHPDM_01853 6.1e-164 S Cell surface protein
MHPHHPDM_01854 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MHPHHPDM_01855 1.3e-262 nox C NADH oxidase
MHPHHPDM_01856 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MHPHHPDM_01857 0.0 pepO 3.4.24.71 O Peptidase family M13
MHPHHPDM_01858 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MHPHHPDM_01859 1.6e-32 copZ P Heavy-metal-associated domain
MHPHHPDM_01860 6.6e-96 dps P Belongs to the Dps family
MHPHHPDM_01861 1.2e-18
MHPHHPDM_01862 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
MHPHHPDM_01863 1.5e-55 txlA O Thioredoxin-like domain
MHPHHPDM_01864 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_01865 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MHPHHPDM_01866 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MHPHHPDM_01867 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
MHPHHPDM_01868 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MHPHHPDM_01869 1.4e-181 yfeX P Peroxidase
MHPHHPDM_01870 1.3e-102 K transcriptional regulator
MHPHHPDM_01871 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
MHPHHPDM_01872 2.6e-65
MHPHHPDM_01874 1.6e-61
MHPHHPDM_01875 2.5e-53
MHPHHPDM_01876 2e-72 mltD CBM50 M PFAM NLP P60 protein
MHPHHPDM_01877 4.6e-279 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
MHPHHPDM_01878 1.8e-27
MHPHHPDM_01879 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MHPHHPDM_01880 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
MHPHHPDM_01881 1.3e-87 K Winged helix DNA-binding domain
MHPHHPDM_01882 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MHPHHPDM_01883 5.1e-129 S WxL domain surface cell wall-binding
MHPHHPDM_01884 2e-56 S Bacterial protein of unknown function (DUF916)
MHPHHPDM_01885 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MHPHHPDM_01886 6.8e-127 yliE T EAL domain
MHPHHPDM_01887 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHPHHPDM_01888 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MHPHHPDM_01889 2e-80
MHPHHPDM_01890 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MHPHHPDM_01891 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHPHHPDM_01892 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPHHPDM_01893 4.9e-22
MHPHHPDM_01894 2.9e-70
MHPHHPDM_01895 1.2e-163 K LysR substrate binding domain
MHPHHPDM_01896 2.4e-243 P Sodium:sulfate symporter transmembrane region
MHPHHPDM_01897 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MHPHHPDM_01898 1.5e-264 S response to antibiotic
MHPHHPDM_01899 2.8e-134 S zinc-ribbon domain
MHPHHPDM_01901 3.2e-37
MHPHHPDM_01902 8.3e-108 aroD S Alpha/beta hydrolase family
MHPHHPDM_01903 1.7e-15 aroD S Alpha/beta hydrolase family
MHPHHPDM_01904 2.6e-176 S Phosphotransferase system, EIIC
MHPHHPDM_01905 2.5e-269 I acetylesterase activity
MHPHHPDM_01906 1.6e-51 sdrF M Collagen binding domain
MHPHHPDM_01907 1.1e-159 yicL EG EamA-like transporter family
MHPHHPDM_01908 1.3e-128 E lipolytic protein G-D-S-L family
MHPHHPDM_01909 1.7e-176 4.1.1.52 S Amidohydrolase
MHPHHPDM_01910 2.5e-112 K Transcriptional regulator C-terminal region
MHPHHPDM_01911 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
MHPHHPDM_01912 4.2e-161 ypbG 2.7.1.2 GK ROK family
MHPHHPDM_01913 0.0 ybfG M peptidoglycan-binding domain-containing protein
MHPHHPDM_01914 5.6e-89
MHPHHPDM_01915 7.6e-132 lmrA 3.6.3.44 V ABC transporter
MHPHHPDM_01916 2.4e-187 lmrA 3.6.3.44 V ABC transporter
MHPHHPDM_01917 5e-93 rmaB K Transcriptional regulator, MarR family
MHPHHPDM_01918 7.1e-159 ccpB 5.1.1.1 K lacI family
MHPHHPDM_01919 3e-121 yceE S haloacid dehalogenase-like hydrolase
MHPHHPDM_01920 1.3e-119 drgA C Nitroreductase family
MHPHHPDM_01921 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MHPHHPDM_01922 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
MHPHHPDM_01923 5.6e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
MHPHHPDM_01924 1.5e-167 XK27_00670 S ABC transporter
MHPHHPDM_01925 1e-260
MHPHHPDM_01926 7.3e-62
MHPHHPDM_01927 2.5e-189 S Cell surface protein
MHPHHPDM_01928 2.3e-91 S WxL domain surface cell wall-binding
MHPHHPDM_01929 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
MHPHHPDM_01930 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
MHPHHPDM_01931 3.3e-124 livF E ABC transporter
MHPHHPDM_01932 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
MHPHHPDM_01933 5.3e-141 livM E Branched-chain amino acid transport system / permease component
MHPHHPDM_01934 2.1e-149 livH U Branched-chain amino acid transport system / permease component
MHPHHPDM_01935 5.4e-212 livJ E Receptor family ligand binding region
MHPHHPDM_01937 7e-33
MHPHHPDM_01938 7.8e-296 S ABC transporter, ATP-binding protein
MHPHHPDM_01939 2e-106 3.2.2.20 K acetyltransferase
MHPHHPDM_01940 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MHPHHPDM_01941 6e-39
MHPHHPDM_01942 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MHPHHPDM_01943 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MHPHHPDM_01944 5e-162 degV S Uncharacterised protein, DegV family COG1307
MHPHHPDM_01945 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
MHPHHPDM_01946 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MHPHHPDM_01947 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MHPHHPDM_01948 3.1e-176 XK27_08835 S ABC transporter
MHPHHPDM_01949 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MHPHHPDM_01950 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
MHPHHPDM_01951 5.7e-258 npr 1.11.1.1 C NADH oxidase
MHPHHPDM_01952 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MHPHHPDM_01953 3.1e-136 terC P membrane
MHPHHPDM_01954 3.1e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MHPHHPDM_01955 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MHPHHPDM_01956 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MHPHHPDM_01957 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MHPHHPDM_01958 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MHPHHPDM_01959 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MHPHHPDM_01960 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MHPHHPDM_01961 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MHPHHPDM_01962 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MHPHHPDM_01963 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MHPHHPDM_01964 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MHPHHPDM_01965 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
MHPHHPDM_01966 4.6e-216 ysaA V RDD family
MHPHHPDM_01967 7.6e-166 corA P CorA-like Mg2+ transporter protein
MHPHHPDM_01968 2.1e-55 S Domain of unknown function (DU1801)
MHPHHPDM_01969 5.9e-91 rmeB K transcriptional regulator, MerR family
MHPHHPDM_01970 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPHHPDM_01971 8.6e-98 J glyoxalase III activity
MHPHHPDM_01972 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MHPHHPDM_01973 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPHHPDM_01974 3.7e-34
MHPHHPDM_01975 2.6e-112 S Protein of unknown function (DUF1211)
MHPHHPDM_01976 0.0 ydgH S MMPL family
MHPHHPDM_01977 1.5e-41 M domain protein
MHPHHPDM_01978 3.9e-219 M domain protein
MHPHHPDM_01979 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
MHPHHPDM_01980 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MHPHHPDM_01981 0.0 glpQ 3.1.4.46 C phosphodiesterase
MHPHHPDM_01982 3.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MHPHHPDM_01983 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_01984 1.1e-172
MHPHHPDM_01985 0.0 typA T GTP-binding protein TypA
MHPHHPDM_01986 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MHPHHPDM_01987 3.3e-46 yktA S Belongs to the UPF0223 family
MHPHHPDM_01988 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
MHPHHPDM_01989 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
MHPHHPDM_01990 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MHPHHPDM_01991 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MHPHHPDM_01992 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MHPHHPDM_01993 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MHPHHPDM_01994 1.6e-85
MHPHHPDM_01995 3.1e-33 ykzG S Belongs to the UPF0356 family
MHPHHPDM_01996 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MHPHHPDM_01997 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MHPHHPDM_01998 1.7e-28
MHPHHPDM_01999 2.6e-107 mltD CBM50 M NlpC P60 family protein
MHPHHPDM_02000 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPHHPDM_02001 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MHPHHPDM_02002 1.6e-120 S Repeat protein
MHPHHPDM_02003 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MHPHHPDM_02004 1.6e-266 N domain, Protein
MHPHHPDM_02005 1.9e-192 S Bacterial protein of unknown function (DUF916)
MHPHHPDM_02006 2.3e-120 N WxL domain surface cell wall-binding
MHPHHPDM_02007 2.6e-115 ktrA P domain protein
MHPHHPDM_02008 1.3e-241 ktrB P Potassium uptake protein
MHPHHPDM_02009 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MHPHHPDM_02010 4.9e-57 XK27_04120 S Putative amino acid metabolism
MHPHHPDM_02011 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
MHPHHPDM_02012 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MHPHHPDM_02013 4.6e-28
MHPHHPDM_02014 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MHPHHPDM_02015 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MHPHHPDM_02016 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MHPHHPDM_02017 1.2e-86 divIVA D DivIVA domain protein
MHPHHPDM_02018 3.4e-146 ylmH S S4 domain protein
MHPHHPDM_02019 1.2e-36 yggT S YGGT family
MHPHHPDM_02020 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MHPHHPDM_02021 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MHPHHPDM_02022 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MHPHHPDM_02023 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MHPHHPDM_02024 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MHPHHPDM_02025 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MHPHHPDM_02026 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MHPHHPDM_02027 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MHPHHPDM_02028 7.5e-54 ftsL D Cell division protein FtsL
MHPHHPDM_02029 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MHPHHPDM_02030 1.9e-77 mraZ K Belongs to the MraZ family
MHPHHPDM_02031 1.9e-62 S Protein of unknown function (DUF3397)
MHPHHPDM_02032 1.6e-174 corA P CorA-like Mg2+ transporter protein
MHPHHPDM_02033 7e-40
MHPHHPDM_02035 1.3e-249 EGP Major facilitator Superfamily
MHPHHPDM_02036 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
MHPHHPDM_02037 4.7e-83 cvpA S Colicin V production protein
MHPHHPDM_02038 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MHPHHPDM_02039 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MHPHHPDM_02040 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MHPHHPDM_02041 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MHPHHPDM_02042 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MHPHHPDM_02043 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
MHPHHPDM_02044 6.5e-96 tag 3.2.2.20 L glycosylase
MHPHHPDM_02045 2.6e-19
MHPHHPDM_02046 2.7e-160 czcD P cation diffusion facilitator family transporter
MHPHHPDM_02047 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_02048 3e-116 hly S protein, hemolysin III
MHPHHPDM_02049 1.1e-44 qacH U Small Multidrug Resistance protein
MHPHHPDM_02050 5.8e-59 qacC P Small Multidrug Resistance protein
MHPHHPDM_02051 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MHPHHPDM_02052 5.3e-179 K AI-2E family transporter
MHPHHPDM_02053 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MHPHHPDM_02054 0.0 kup P Transport of potassium into the cell
MHPHHPDM_02056 2.3e-257 yhdG E C-terminus of AA_permease
MHPHHPDM_02057 2.1e-82
MHPHHPDM_02059 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MHPHHPDM_02060 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
MHPHHPDM_02061 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHPHHPDM_02062 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MHPHHPDM_02063 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MHPHHPDM_02064 9.8e-55 S Enterocin A Immunity
MHPHHPDM_02065 1.9e-258 gor 1.8.1.7 C Glutathione reductase
MHPHHPDM_02066 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MHPHHPDM_02067 4.2e-183 D Alpha beta
MHPHHPDM_02068 6.9e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
MHPHHPDM_02069 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
MHPHHPDM_02070 5e-117 yugP S Putative neutral zinc metallopeptidase
MHPHHPDM_02071 4.1e-25
MHPHHPDM_02072 7.1e-145 DegV S EDD domain protein, DegV family
MHPHHPDM_02073 7.3e-127 lrgB M LrgB-like family
MHPHHPDM_02074 5.1e-64 lrgA S LrgA family
MHPHHPDM_02075 3.8e-104 J Acetyltransferase (GNAT) domain
MHPHHPDM_02076 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
MHPHHPDM_02077 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
MHPHHPDM_02078 5.4e-36 S Phospholipase_D-nuclease N-terminal
MHPHHPDM_02079 7.1e-59 S Enterocin A Immunity
MHPHHPDM_02080 1.3e-87 perR P Belongs to the Fur family
MHPHHPDM_02081 8.4e-105
MHPHHPDM_02082 7.9e-238 S module of peptide synthetase
MHPHHPDM_02083 1.1e-77 S NADPH-dependent FMN reductase
MHPHHPDM_02084 1.4e-08
MHPHHPDM_02085 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
MHPHHPDM_02086 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MHPHHPDM_02087 9e-156 1.6.5.2 GM NmrA-like family
MHPHHPDM_02088 2e-77 merR K MerR family regulatory protein
MHPHHPDM_02089 6.6e-113 zmp3 O Zinc-dependent metalloprotease
MHPHHPDM_02090 2.8e-82 gtrA S GtrA-like protein
MHPHHPDM_02091 6.1e-122 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_02092 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
MHPHHPDM_02093 6.8e-72 T Belongs to the universal stress protein A family
MHPHHPDM_02094 1.1e-46
MHPHHPDM_02095 1.9e-116 S SNARE associated Golgi protein
MHPHHPDM_02096 2e-49 K Transcriptional regulator, ArsR family
MHPHHPDM_02097 1.2e-95 cadD P Cadmium resistance transporter
MHPHHPDM_02098 0.0 yhcA V ABC transporter, ATP-binding protein
MHPHHPDM_02099 2.3e-24 P Concanavalin A-like lectin/glucanases superfamily
MHPHHPDM_02101 7.4e-64
MHPHHPDM_02102 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
MHPHHPDM_02103 3.2e-55
MHPHHPDM_02104 5.3e-150 dicA K Helix-turn-helix domain
MHPHHPDM_02105 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHPHHPDM_02106 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_02107 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02108 9.2e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02109 5.3e-184 1.1.1.219 GM Male sterility protein
MHPHHPDM_02110 5.1e-75 K helix_turn_helix, mercury resistance
MHPHHPDM_02111 2.3e-65 M LysM domain
MHPHHPDM_02112 6.7e-87 M Lysin motif
MHPHHPDM_02113 1.8e-107 S SdpI/YhfL protein family
MHPHHPDM_02114 1.8e-54 nudA S ASCH
MHPHHPDM_02115 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
MHPHHPDM_02116 4.2e-92
MHPHHPDM_02117 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
MHPHHPDM_02118 3.3e-219 T diguanylate cyclase
MHPHHPDM_02119 1.2e-73 S Psort location Cytoplasmic, score
MHPHHPDM_02120 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MHPHHPDM_02121 8.6e-218 ykiI
MHPHHPDM_02122 0.0 V ABC transporter
MHPHHPDM_02123 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
MHPHHPDM_02125 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
MHPHHPDM_02126 7.7e-163 IQ KR domain
MHPHHPDM_02128 7.4e-71
MHPHHPDM_02129 4.3e-144 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_02130 9.6e-267 yjeM E Amino Acid
MHPHHPDM_02131 1.1e-65 lysM M LysM domain
MHPHHPDM_02132 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MHPHHPDM_02133 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MHPHHPDM_02134 0.0 ctpA 3.6.3.54 P P-type ATPase
MHPHHPDM_02135 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MHPHHPDM_02136 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MHPHHPDM_02137 2.1e-244 dinF V MatE
MHPHHPDM_02138 1.9e-31
MHPHHPDM_02140 1.5e-77 elaA S Acetyltransferase (GNAT) domain
MHPHHPDM_02141 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MHPHHPDM_02142 1.4e-81
MHPHHPDM_02143 0.0 yhcA V MacB-like periplasmic core domain
MHPHHPDM_02144 1.1e-105
MHPHHPDM_02145 0.0 K PRD domain
MHPHHPDM_02146 2.4e-62 S Domain of unknown function (DUF3284)
MHPHHPDM_02147 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MHPHHPDM_02148 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_02149 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02150 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02151 9.5e-209 EGP Major facilitator Superfamily
MHPHHPDM_02152 1.5e-112 M ErfK YbiS YcfS YnhG
MHPHHPDM_02153 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MHPHHPDM_02154 2.4e-283 ydfD K Alanine-glyoxylate amino-transferase
MHPHHPDM_02155 1.4e-102 argO S LysE type translocator
MHPHHPDM_02156 7.1e-214 arcT 2.6.1.1 E Aminotransferase
MHPHHPDM_02157 4.4e-77 argR K Regulates arginine biosynthesis genes
MHPHHPDM_02158 2.9e-12
MHPHHPDM_02159 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MHPHHPDM_02160 1e-54 yheA S Belongs to the UPF0342 family
MHPHHPDM_02161 5.7e-233 yhaO L Ser Thr phosphatase family protein
MHPHHPDM_02162 0.0 L AAA domain
MHPHHPDM_02163 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPHHPDM_02164 2.1e-213
MHPHHPDM_02165 3.1e-181 3.4.21.102 M Peptidase family S41
MHPHHPDM_02166 7.6e-177 K LysR substrate binding domain
MHPHHPDM_02167 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
MHPHHPDM_02168 0.0 1.3.5.4 C FAD binding domain
MHPHHPDM_02169 1.7e-99
MHPHHPDM_02170 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MHPHHPDM_02171 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
MHPHHPDM_02172 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPHHPDM_02173 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MHPHHPDM_02174 1.7e-19 S NUDIX domain
MHPHHPDM_02175 0.0 S membrane
MHPHHPDM_02176 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MHPHHPDM_02177 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MHPHHPDM_02178 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MHPHHPDM_02179 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MHPHHPDM_02180 9.3e-106 GBS0088 S Nucleotidyltransferase
MHPHHPDM_02181 5.5e-106
MHPHHPDM_02182 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MHPHHPDM_02183 4.7e-74 K Bacterial regulatory proteins, tetR family
MHPHHPDM_02184 4.4e-35 yyaN K MerR HTH family regulatory protein
MHPHHPDM_02185 1.7e-120 azlC E branched-chain amino acid
MHPHHPDM_02186 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
MHPHHPDM_02187 0.0 asnB 6.3.5.4 E Asparagine synthase
MHPHHPDM_02188 1e-218 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MHPHHPDM_02189 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MHPHHPDM_02190 1e-254 xylP2 G symporter
MHPHHPDM_02191 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
MHPHHPDM_02192 5.6e-49
MHPHHPDM_02193 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MHPHHPDM_02194 2e-91 3.2.2.20 K FR47-like protein
MHPHHPDM_02195 3.4e-127 yibF S overlaps another CDS with the same product name
MHPHHPDM_02196 1.4e-218 yibE S overlaps another CDS with the same product name
MHPHHPDM_02197 3.9e-179
MHPHHPDM_02198 5.6e-138 S NADPH-dependent FMN reductase
MHPHHPDM_02199 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_02200 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MHPHHPDM_02201 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MHPHHPDM_02202 4.1e-32 L leucine-zipper of insertion element IS481
MHPHHPDM_02203 8.5e-41
MHPHHPDM_02204 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MHPHHPDM_02205 6.7e-278 pipD E Dipeptidase
MHPHHPDM_02206 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
MHPHHPDM_02207 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MHPHHPDM_02208 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MHPHHPDM_02209 2.3e-81 rmaD K Transcriptional regulator
MHPHHPDM_02211 1.3e-210 1.3.5.4 C FMN_bind
MHPHHPDM_02212 1.2e-97 1.3.5.4 C FMN_bind
MHPHHPDM_02213 2.8e-171 K Transcriptional regulator
MHPHHPDM_02214 5.2e-41 K Helix-turn-helix domain
MHPHHPDM_02215 7.2e-47 K Helix-turn-helix domain
MHPHHPDM_02216 2.3e-139 K sequence-specific DNA binding
MHPHHPDM_02217 6.5e-87 S AAA domain
MHPHHPDM_02219 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
MHPHHPDM_02220 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
MHPHHPDM_02221 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
MHPHHPDM_02222 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
MHPHHPDM_02223 2.7e-171 L Belongs to the 'phage' integrase family
MHPHHPDM_02224 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MHPHHPDM_02225 1.7e-151 hsdM 2.1.1.72 V type I restriction-modification system
MHPHHPDM_02226 3.7e-95 hsdM 2.1.1.72 V type I restriction-modification system
MHPHHPDM_02227 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MHPHHPDM_02228 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MHPHHPDM_02229 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
MHPHHPDM_02230 7.4e-102 M Protein of unknown function (DUF3737)
MHPHHPDM_02231 1.2e-194 C Aldo/keto reductase family
MHPHHPDM_02233 0.0 mdlB V ABC transporter
MHPHHPDM_02234 0.0 mdlA V ABC transporter
MHPHHPDM_02235 1.3e-246 EGP Major facilitator Superfamily
MHPHHPDM_02240 1e-197 yhgE V domain protein
MHPHHPDM_02241 1.5e-95 K Transcriptional regulator (TetR family)
MHPHHPDM_02242 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
MHPHHPDM_02243 1.7e-139 endA F DNA RNA non-specific endonuclease
MHPHHPDM_02244 6.3e-99 speG J Acetyltransferase (GNAT) domain
MHPHHPDM_02245 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
MHPHHPDM_02246 1.1e-223 S CAAX protease self-immunity
MHPHHPDM_02247 1.2e-307 ybiT S ABC transporter, ATP-binding protein
MHPHHPDM_02248 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
MHPHHPDM_02249 0.0 S Predicted membrane protein (DUF2207)
MHPHHPDM_02250 0.0 uvrA3 L excinuclease ABC
MHPHHPDM_02251 3.1e-207 EGP Major facilitator Superfamily
MHPHHPDM_02252 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
MHPHHPDM_02253 2e-233 yxiO S Vacuole effluxer Atg22 like
MHPHHPDM_02254 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
MHPHHPDM_02255 1.1e-158 I alpha/beta hydrolase fold
MHPHHPDM_02256 7e-130 treR K UTRA
MHPHHPDM_02257 1.2e-234
MHPHHPDM_02258 5.6e-39 S Cytochrome B5
MHPHHPDM_02259 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MHPHHPDM_02260 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MHPHHPDM_02261 9.2e-131 znuB U ABC 3 transport family
MHPHHPDM_02262 9.8e-129 fhuC 3.6.3.35 P ABC transporter
MHPHHPDM_02263 1.3e-181 S Prolyl oligopeptidase family
MHPHHPDM_02264 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MHPHHPDM_02265 3.2e-37 veg S Biofilm formation stimulator VEG
MHPHHPDM_02266 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MHPHHPDM_02267 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MHPHHPDM_02268 1.5e-146 tatD L hydrolase, TatD family
MHPHHPDM_02270 1.3e-83 mutR K sequence-specific DNA binding
MHPHHPDM_02271 2e-214 bcr1 EGP Major facilitator Superfamily
MHPHHPDM_02272 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MHPHHPDM_02273 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
MHPHHPDM_02274 2e-160 yunF F Protein of unknown function DUF72
MHPHHPDM_02275 2.5e-132 cobB K SIR2 family
MHPHHPDM_02276 2.7e-177
MHPHHPDM_02277 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MHPHHPDM_02278 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MHPHHPDM_02279 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MHPHHPDM_02280 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHPHHPDM_02281 4.8e-34
MHPHHPDM_02282 4.9e-75 S Domain of unknown function (DUF3284)
MHPHHPDM_02283 3.9e-24
MHPHHPDM_02284 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02285 9e-130 K UbiC transcription regulator-associated domain protein
MHPHHPDM_02286 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MHPHHPDM_02287 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MHPHHPDM_02288 0.0 helD 3.6.4.12 L DNA helicase
MHPHHPDM_02289 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
MHPHHPDM_02290 9.6e-113 S CAAX protease self-immunity
MHPHHPDM_02291 1.2e-110 V CAAX protease self-immunity
MHPHHPDM_02292 7.4e-118 ypbD S CAAX protease self-immunity
MHPHHPDM_02293 1.4e-108 S CAAX protease self-immunity
MHPHHPDM_02294 7.5e-242 mesE M Transport protein ComB
MHPHHPDM_02295 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MHPHHPDM_02296 5.5e-13
MHPHHPDM_02297 2.4e-22 plnF
MHPHHPDM_02298 2.2e-129 S CAAX protease self-immunity
MHPHHPDM_02299 1.3e-189 ynfM EGP Major facilitator Superfamily
MHPHHPDM_02300 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MHPHHPDM_02301 4.1e-270 lmrB EGP Major facilitator Superfamily
MHPHHPDM_02302 2e-75 S Domain of unknown function (DUF4811)
MHPHHPDM_02303 1.8e-101 rimL J Acetyltransferase (GNAT) domain
MHPHHPDM_02304 9.3e-173 S Conserved hypothetical protein 698
MHPHHPDM_02305 4.8e-151 rlrG K Transcriptional regulator
MHPHHPDM_02306 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MHPHHPDM_02307 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
MHPHHPDM_02309 1.8e-46 lytE M LysM domain
MHPHHPDM_02310 1.2e-91 ogt 2.1.1.63 L Methyltransferase
MHPHHPDM_02311 7.5e-166 natA S ABC transporter, ATP-binding protein
MHPHHPDM_02312 1.4e-210 natB CP ABC-2 family transporter protein
MHPHHPDM_02313 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPHHPDM_02314 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
MHPHHPDM_02315 3.2e-76 yphH S Cupin domain
MHPHHPDM_02316 2.9e-78 K transcriptional regulator, MerR family
MHPHHPDM_02317 1.4e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MHPHHPDM_02318 0.0 ylbB V ABC transporter permease
MHPHHPDM_02319 7.5e-121 macB V ABC transporter, ATP-binding protein
MHPHHPDM_02321 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MHPHHPDM_02322 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MHPHHPDM_02323 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MHPHHPDM_02325 3.8e-84
MHPHHPDM_02326 2.8e-85 yvbK 3.1.3.25 K GNAT family
MHPHHPDM_02327 3.2e-37
MHPHHPDM_02328 8.2e-48
MHPHHPDM_02329 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
MHPHHPDM_02330 3.8e-63 S Domain of unknown function (DUF4440)
MHPHHPDM_02331 6.9e-156 K LysR substrate binding domain
MHPHHPDM_02332 1.9e-104 GM NAD(P)H-binding
MHPHHPDM_02333 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MHPHHPDM_02334 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MHPHHPDM_02335 1.3e-34
MHPHHPDM_02336 6.1e-76 T Belongs to the universal stress protein A family
MHPHHPDM_02337 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MHPHHPDM_02338 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MHPHHPDM_02339 2.1e-31
MHPHHPDM_02340 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
MHPHHPDM_02341 4.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MHPHHPDM_02342 0.0 rafA 3.2.1.22 G alpha-galactosidase
MHPHHPDM_02343 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MHPHHPDM_02344 1.5e-304 scrB 3.2.1.26 GH32 G invertase
MHPHHPDM_02345 5.9e-172 scrR K Transcriptional regulator, LacI family
MHPHHPDM_02346 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MHPHHPDM_02347 1.4e-164 3.5.1.10 C nadph quinone reductase
MHPHHPDM_02348 1.1e-217 nhaC C Na H antiporter NhaC
MHPHHPDM_02349 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MHPHHPDM_02350 2.9e-128 mleR K LysR substrate binding domain
MHPHHPDM_02351 5e-27 mleR K LysR substrate binding domain
MHPHHPDM_02352 0.0 3.6.4.13 M domain protein
MHPHHPDM_02354 2.1e-157 hipB K Helix-turn-helix
MHPHHPDM_02355 0.0 oppA E ABC transporter, substratebinding protein
MHPHHPDM_02356 1.8e-309 oppA E ABC transporter, substratebinding protein
MHPHHPDM_02357 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
MHPHHPDM_02358 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MHPHHPDM_02359 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MHPHHPDM_02360 3e-113 pgm1 G phosphoglycerate mutase
MHPHHPDM_02361 7.2e-178 yghZ C Aldo keto reductase family protein
MHPHHPDM_02362 4.9e-34
MHPHHPDM_02363 1.3e-60 S Domain of unknown function (DU1801)
MHPHHPDM_02364 2.9e-162 FbpA K Domain of unknown function (DUF814)
MHPHHPDM_02365 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPHHPDM_02367 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPHHPDM_02368 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MHPHHPDM_02369 2.6e-212 S ATPases associated with a variety of cellular activities
MHPHHPDM_02370 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHPHHPDM_02371 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MHPHHPDM_02372 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_02373 3.7e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
MHPHHPDM_02374 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
MHPHHPDM_02375 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MHPHHPDM_02376 1.1e-147 cof S haloacid dehalogenase-like hydrolase
MHPHHPDM_02377 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
MHPHHPDM_02378 9.4e-77
MHPHHPDM_02379 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MHPHHPDM_02380 1.4e-116 ybbL S ABC transporter, ATP-binding protein
MHPHHPDM_02381 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
MHPHHPDM_02382 2.6e-205 S DUF218 domain
MHPHHPDM_02383 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MHPHHPDM_02384 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MHPHHPDM_02385 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MHPHHPDM_02386 2.1e-126 S Putative adhesin
MHPHHPDM_02387 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
MHPHHPDM_02388 9.8e-52 K Transcriptional regulator
MHPHHPDM_02389 5.8e-79 KT response to antibiotic
MHPHHPDM_02390 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHPHHPDM_02391 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_02392 8.1e-123 tcyB E ABC transporter
MHPHHPDM_02393 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MHPHHPDM_02394 1.9e-236 EK Aminotransferase, class I
MHPHHPDM_02395 2.1e-168 K LysR substrate binding domain
MHPHHPDM_02396 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_02397 2.9e-253 S Bacterial membrane protein YfhO
MHPHHPDM_02398 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
MHPHHPDM_02399 3.6e-11
MHPHHPDM_02400 9e-13 ytgB S Transglycosylase associated protein
MHPHHPDM_02401 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
MHPHHPDM_02402 4.9e-78 yneH 1.20.4.1 K ArsC family
MHPHHPDM_02403 7.4e-135 K LytTr DNA-binding domain
MHPHHPDM_02404 8.7e-160 2.7.13.3 T GHKL domain
MHPHHPDM_02405 1.8e-12
MHPHHPDM_02406 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MHPHHPDM_02407 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MHPHHPDM_02409 5.1e-57 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MHPHHPDM_02410 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MHPHHPDM_02411 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPHHPDM_02412 8.7e-72 K Transcriptional regulator
MHPHHPDM_02413 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MHPHHPDM_02414 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MHPHHPDM_02415 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MHPHHPDM_02416 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
MHPHHPDM_02417 1.1e-86 gutM K Glucitol operon activator protein (GutM)
MHPHHPDM_02418 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MHPHHPDM_02419 3.8e-145 IQ NAD dependent epimerase/dehydratase family
MHPHHPDM_02420 2.7e-160 rbsU U ribose uptake protein RbsU
MHPHHPDM_02421 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MHPHHPDM_02422 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MHPHHPDM_02423 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
MHPHHPDM_02425 3e-08
MHPHHPDM_02426 9.1e-50
MHPHHPDM_02427 2.4e-114 K UTRA
MHPHHPDM_02428 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02429 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02430 4.1e-65
MHPHHPDM_02431 6.4e-63 S Protein of unknown function (DUF1093)
MHPHHPDM_02432 4.3e-207 S Membrane
MHPHHPDM_02433 1.1e-43 S Protein of unknown function (DUF3781)
MHPHHPDM_02434 1e-107 ydeA S intracellular protease amidase
MHPHHPDM_02435 2.2e-41 K HxlR-like helix-turn-helix
MHPHHPDM_02436 3.3e-66
MHPHHPDM_02437 1e-64 V ABC transporter
MHPHHPDM_02438 2.3e-51 K Helix-turn-helix domain
MHPHHPDM_02439 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MHPHHPDM_02440 1.4e-46 K Helix-turn-helix domain
MHPHHPDM_02441 1.2e-90 S ABC-2 family transporter protein
MHPHHPDM_02442 5.7e-58 S ABC-2 family transporter protein
MHPHHPDM_02443 4.6e-91 V ABC transporter, ATP-binding protein
MHPHHPDM_02444 8.8e-40
MHPHHPDM_02445 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MHPHHPDM_02446 4.9e-172 K AI-2E family transporter
MHPHHPDM_02447 1.7e-210 xylR GK ROK family
MHPHHPDM_02448 2.3e-81
MHPHHPDM_02449 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MHPHHPDM_02450 3.9e-162
MHPHHPDM_02451 3.2e-200 KLT Protein tyrosine kinase
MHPHHPDM_02452 2.9e-23 S Protein of unknown function (DUF4064)
MHPHHPDM_02453 6e-97 S Domain of unknown function (DUF4352)
MHPHHPDM_02454 3.9e-75 S Psort location Cytoplasmic, score
MHPHHPDM_02455 0.0 lacS G Transporter
MHPHHPDM_02456 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MHPHHPDM_02457 1.1e-173 galR K Transcriptional regulator
MHPHHPDM_02458 3.1e-192 C Aldo keto reductase family protein
MHPHHPDM_02459 5.2e-65 S pyridoxamine 5-phosphate
MHPHHPDM_02460 0.0 1.3.5.4 C FAD binding domain
MHPHHPDM_02461 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MHPHHPDM_02462 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MHPHHPDM_02463 2.7e-214 ydiM G Transporter
MHPHHPDM_02464 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MHPHHPDM_02465 3.4e-163 K Transcriptional regulator, LysR family
MHPHHPDM_02466 1.8e-210 ydiN G Major Facilitator Superfamily
MHPHHPDM_02467 1e-63
MHPHHPDM_02468 3.4e-154 estA S Putative esterase
MHPHHPDM_02469 1.2e-134 K UTRA domain
MHPHHPDM_02470 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02471 4.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MHPHHPDM_02472 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MHPHHPDM_02473 1.1e-211 S Bacterial protein of unknown function (DUF871)
MHPHHPDM_02474 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02475 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MHPHHPDM_02476 1.3e-154 licT K CAT RNA binding domain
MHPHHPDM_02477 3.4e-171 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02478 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPHHPDM_02479 4.3e-144 yxeH S hydrolase
MHPHHPDM_02480 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MHPHHPDM_02481 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MHPHHPDM_02482 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MHPHHPDM_02483 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
MHPHHPDM_02484 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHPHHPDM_02485 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHPHHPDM_02486 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
MHPHHPDM_02487 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MHPHHPDM_02488 1.1e-231 gatC G PTS system sugar-specific permease component
MHPHHPDM_02489 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MHPHHPDM_02490 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MHPHHPDM_02491 7e-112 K DeoR C terminal sensor domain
MHPHHPDM_02492 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MHPHHPDM_02493 7.4e-136 K Helix-turn-helix domain, rpiR family
MHPHHPDM_02494 3.7e-72 yueI S Protein of unknown function (DUF1694)
MHPHHPDM_02495 2.6e-38 I alpha/beta hydrolase fold
MHPHHPDM_02496 1.6e-99 I alpha/beta hydrolase fold
MHPHHPDM_02497 1.3e-159 I alpha/beta hydrolase fold
MHPHHPDM_02498 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MHPHHPDM_02499 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHPHHPDM_02500 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
MHPHHPDM_02501 5.4e-153 nanK GK ROK family
MHPHHPDM_02502 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MHPHHPDM_02503 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MHPHHPDM_02504 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
MHPHHPDM_02505 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MHPHHPDM_02506 3.7e-44
MHPHHPDM_02507 3.2e-20 zmp1 O Zinc-dependent metalloprotease
MHPHHPDM_02508 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MHPHHPDM_02509 4.2e-310 mco Q Multicopper oxidase
MHPHHPDM_02510 1.1e-54 ypaA S Protein of unknown function (DUF1304)
MHPHHPDM_02511 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
MHPHHPDM_02512 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
MHPHHPDM_02513 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MHPHHPDM_02514 9.3e-80
MHPHHPDM_02515 2.7e-68 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MHPHHPDM_02516 4.5e-174 rihC 3.2.2.1 F Nucleoside
MHPHHPDM_02517 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
MHPHHPDM_02518 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
MHPHHPDM_02519 1.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MHPHHPDM_02520 9.9e-180 proV E ABC transporter, ATP-binding protein
MHPHHPDM_02521 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
MHPHHPDM_02522 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MHPHHPDM_02523 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MHPHHPDM_02524 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MHPHHPDM_02525 1.1e-235 M domain protein
MHPHHPDM_02526 5.1e-52 U domain, Protein
MHPHHPDM_02527 4.4e-25 S Immunity protein 74
MHPHHPDM_02528 2.9e-131 ydfG S KR domain
MHPHHPDM_02529 8.3e-63 hxlR K HxlR-like helix-turn-helix
MHPHHPDM_02530 1e-47 S Domain of unknown function (DUF1905)
MHPHHPDM_02531 0.0 M Glycosyl hydrolases family 25
MHPHHPDM_02532 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MHPHHPDM_02533 2e-166 GM NmrA-like family
MHPHHPDM_02534 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
MHPHHPDM_02535 4.3e-204 2.7.13.3 T GHKL domain
MHPHHPDM_02536 8.2e-134 K LytTr DNA-binding domain
MHPHHPDM_02537 0.0 asnB 6.3.5.4 E Asparagine synthase
MHPHHPDM_02538 1.4e-94 M ErfK YbiS YcfS YnhG
MHPHHPDM_02539 5.1e-210 ytbD EGP Major facilitator Superfamily
MHPHHPDM_02540 2e-61 K Transcriptional regulator, HxlR family
MHPHHPDM_02541 1e-116 S Haloacid dehalogenase-like hydrolase
MHPHHPDM_02542 5.9e-117
MHPHHPDM_02543 6.9e-210 NU Mycoplasma protein of unknown function, DUF285
MHPHHPDM_02544 1.1e-62
MHPHHPDM_02545 2.2e-100 S WxL domain surface cell wall-binding
MHPHHPDM_02546 2.4e-187 S Cell surface protein
MHPHHPDM_02547 1.8e-113 S GyrI-like small molecule binding domain
MHPHHPDM_02548 1.3e-66 S Iron-sulphur cluster biosynthesis
MHPHHPDM_02549 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
MHPHHPDM_02550 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MHPHHPDM_02551 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MHPHHPDM_02552 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
MHPHHPDM_02553 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MHPHHPDM_02554 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MHPHHPDM_02555 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MHPHHPDM_02556 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
MHPHHPDM_02557 9.4e-297 S Alpha beta
MHPHHPDM_02558 1.8e-23
MHPHHPDM_02559 3e-99 S ECF transporter, substrate-specific component
MHPHHPDM_02560 5.8e-253 yfnA E Amino Acid
MHPHHPDM_02561 1.4e-165 mleP S Sodium Bile acid symporter family
MHPHHPDM_02562 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MHPHHPDM_02563 1.2e-166 mleR K LysR family
MHPHHPDM_02564 4.9e-162 mleR K LysR family transcriptional regulator
MHPHHPDM_02565 1e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MHPHHPDM_02566 1.5e-261 frdC 1.3.5.4 C FAD binding domain
MHPHHPDM_02567 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MHPHHPDM_02574 5.5e-08
MHPHHPDM_02582 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MHPHHPDM_02583 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
MHPHHPDM_02584 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MHPHHPDM_02585 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MHPHHPDM_02586 2e-13 coiA 3.6.4.12 S Competence protein
MHPHHPDM_02587 2e-180 coiA 3.6.4.12 S Competence protein
MHPHHPDM_02588 0.0 pepF E oligoendopeptidase F
MHPHHPDM_02589 3.6e-114 yjbH Q Thioredoxin
MHPHHPDM_02590 6e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
MHPHHPDM_02591 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MHPHHPDM_02592 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MHPHHPDM_02593 1.1e-115 cutC P Participates in the control of copper homeostasis
MHPHHPDM_02594 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MHPHHPDM_02595 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MHPHHPDM_02596 4.3e-206 XK27_05220 S AI-2E family transporter
MHPHHPDM_02597 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MHPHHPDM_02598 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
MHPHHPDM_02600 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
MHPHHPDM_02601 2.4e-113 ywnB S NAD(P)H-binding
MHPHHPDM_02602 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MHPHHPDM_02603 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MHPHHPDM_02604 1.8e-84 hmpT S Pfam:DUF3816
MHPHHPDM_02605 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MHPHHPDM_02606 3.9e-111
MHPHHPDM_02607 2.4e-149 M Glycosyl hydrolases family 25
MHPHHPDM_02608 2e-143 yvpB S Peptidase_C39 like family
MHPHHPDM_02609 1.1e-92 yueI S Protein of unknown function (DUF1694)
MHPHHPDM_02610 1.6e-115 S Protein of unknown function (DUF554)
MHPHHPDM_02611 6.4e-148 KT helix_turn_helix, mercury resistance
MHPHHPDM_02612 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MHPHHPDM_02613 6.6e-95 S Protein of unknown function (DUF1440)
MHPHHPDM_02614 5.2e-174 hrtB V ABC transporter permease
MHPHHPDM_02615 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MHPHHPDM_02616 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
MHPHHPDM_02617 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MHPHHPDM_02618 8.1e-99 1.5.1.3 H RibD C-terminal domain
MHPHHPDM_02619 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MHPHHPDM_02620 6.4e-117 S Membrane
MHPHHPDM_02621 1.2e-155 mleP3 S Membrane transport protein
MHPHHPDM_02622 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
MHPHHPDM_02623 6.5e-47
MHPHHPDM_02624 1.3e-57
MHPHHPDM_02625 2.3e-164
MHPHHPDM_02626 1.3e-72 K Transcriptional regulator
MHPHHPDM_02627 0.0 pepF2 E Oligopeptidase F
MHPHHPDM_02628 3.8e-173 D Alpha beta
MHPHHPDM_02629 1.2e-45 S Enterocin A Immunity
MHPHHPDM_02630 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
MHPHHPDM_02631 8.7e-125 skfE V ABC transporter
MHPHHPDM_02632 2.7e-132
MHPHHPDM_02633 3.7e-107 pncA Q Isochorismatase family
MHPHHPDM_02634 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MHPHHPDM_02635 0.0 yjcE P Sodium proton antiporter
MHPHHPDM_02636 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
MHPHHPDM_02637 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
MHPHHPDM_02638 1.1e-116 K Helix-turn-helix domain, rpiR family
MHPHHPDM_02639 2.3e-157 ccpB 5.1.1.1 K lacI family
MHPHHPDM_02640 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
MHPHHPDM_02641 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MHPHHPDM_02642 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
MHPHHPDM_02643 1.2e-97 drgA C Nitroreductase family
MHPHHPDM_02644 3.6e-168 S Polyphosphate kinase 2 (PPK2)
MHPHHPDM_02645 7.4e-67 gcvH E Glycine cleavage H-protein
MHPHHPDM_02646 2.8e-176 sepS16B
MHPHHPDM_02647 1.8e-130
MHPHHPDM_02648 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MHPHHPDM_02649 6.8e-57
MHPHHPDM_02650 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPHHPDM_02651 4.9e-24 elaA S GNAT family
MHPHHPDM_02652 8.4e-75 K Transcriptional regulator
MHPHHPDM_02653 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
MHPHHPDM_02654 4.3e-40
MHPHHPDM_02655 1.5e-205 potD P ABC transporter
MHPHHPDM_02656 2.9e-140 potC P ABC transporter permease
MHPHHPDM_02657 4.5e-149 potB P ABC transporter permease
MHPHHPDM_02658 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MHPHHPDM_02659 1.3e-96 puuR K Cupin domain
MHPHHPDM_02660 1.1e-83 6.3.3.2 S ASCH
MHPHHPDM_02661 1e-84 K GNAT family
MHPHHPDM_02662 8e-91 K acetyltransferase
MHPHHPDM_02663 8.1e-22
MHPHHPDM_02664 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
MHPHHPDM_02665 2e-163 ytrB V ABC transporter
MHPHHPDM_02666 4.9e-190
MHPHHPDM_02667 4.7e-241 amtB P ammonium transporter
MHPHHPDM_02668 1.3e-257 P Major Facilitator Superfamily
MHPHHPDM_02669 2.8e-91 K Transcriptional regulator PadR-like family
MHPHHPDM_02670 8.4e-44
MHPHHPDM_02671 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MHPHHPDM_02672 6e-154 tagG U Transport permease protein
MHPHHPDM_02673 3.8e-218
MHPHHPDM_02674 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
MHPHHPDM_02675 1.8e-61 S CHY zinc finger
MHPHHPDM_02676 1.1e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MHPHHPDM_02677 5.7e-95 bioY S BioY family
MHPHHPDM_02678 3e-40
MHPHHPDM_02679 6.5e-281 pipD E Dipeptidase
MHPHHPDM_02680 1.1e-29
MHPHHPDM_02681 8.7e-122 qmcA O prohibitin homologues
MHPHHPDM_02682 1.5e-239 xylP1 G MFS/sugar transport protein
MHPHHPDM_02684 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MHPHHPDM_02685 1.8e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
MHPHHPDM_02686 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MHPHHPDM_02687 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MHPHHPDM_02688 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MHPHHPDM_02689 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MHPHHPDM_02690 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MHPHHPDM_02691 9.3e-109 tdk 2.7.1.21 F thymidine kinase
MHPHHPDM_02692 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MHPHHPDM_02693 6.5e-136 cobQ S glutamine amidotransferase
MHPHHPDM_02694 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
MHPHHPDM_02695 1.2e-191 ampC V Beta-lactamase
MHPHHPDM_02696 5.2e-29
MHPHHPDM_02697 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MHPHHPDM_02698 1.9e-58
MHPHHPDM_02699 2.8e-126
MHPHHPDM_02700 0.0 yfiC V ABC transporter
MHPHHPDM_02701 2.2e-310 ycfI V ABC transporter, ATP-binding protein
MHPHHPDM_02702 3.3e-65 S Protein of unknown function (DUF1093)
MHPHHPDM_02703 1.3e-132 yxkH G Polysaccharide deacetylase
MHPHHPDM_02705 2.3e-219 S Bacterial membrane protein YfhO
MHPHHPDM_02706 1.2e-225 nupG F Nucleoside
MHPHHPDM_02707 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MHPHHPDM_02708 7.9e-149 noc K Belongs to the ParB family
MHPHHPDM_02709 1.8e-136 soj D Sporulation initiation inhibitor
MHPHHPDM_02710 2.4e-156 spo0J K Belongs to the ParB family
MHPHHPDM_02711 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
MHPHHPDM_02712 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MHPHHPDM_02713 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
MHPHHPDM_02714 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MHPHHPDM_02715 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MHPHHPDM_02716 5.5e-124 yoaK S Protein of unknown function (DUF1275)
MHPHHPDM_02717 3.2e-124 K response regulator
MHPHHPDM_02718 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
MHPHHPDM_02719 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MHPHHPDM_02720 3.2e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MHPHHPDM_02721 5.1e-131 azlC E branched-chain amino acid
MHPHHPDM_02722 2.3e-54 azlD S branched-chain amino acid
MHPHHPDM_02723 5.2e-109 S membrane transporter protein
MHPHHPDM_02724 2.6e-30
MHPHHPDM_02725 0.0 lacA 3.2.1.23 G -beta-galactosidase
MHPHHPDM_02726 0.0 lacS G Transporter
MHPHHPDM_02727 5.9e-68 brnQ U Component of the transport system for branched-chain amino acids
MHPHHPDM_02728 1e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MHPHHPDM_02729 1e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MHPHHPDM_02731 0.0 O Belongs to the peptidase S8 family
MHPHHPDM_02732 5.3e-19
MHPHHPDM_02733 2.6e-79
MHPHHPDM_02734 2.8e-21 L Transposase
MHPHHPDM_02735 2.5e-175 nsr 3.4.21.102 M Peptidase family S41
MHPHHPDM_02736 2.3e-96 K Helix-turn-helix domain
MHPHHPDM_02738 1.2e-29
MHPHHPDM_02739 6.8e-10 K Helix-turn-helix XRE-family like proteins
MHPHHPDM_02740 4.8e-62 S Protein of unknown function (DUF2992)
MHPHHPDM_02741 3.2e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MHPHHPDM_02742 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MHPHHPDM_02743 2.8e-105 L Integrase
MHPHHPDM_02744 6.1e-45 S Phage derived protein Gp49-like (DUF891)
MHPHHPDM_02745 1.7e-36 K sequence-specific DNA binding
MHPHHPDM_02746 1.1e-54 S Bacterial mobilisation protein (MobC)
MHPHHPDM_02747 1.6e-184 U Relaxase/Mobilisation nuclease domain
MHPHHPDM_02748 2.8e-55 repA S Replication initiator protein A
MHPHHPDM_02749 2.7e-42
MHPHHPDM_02750 0.0 pacL 3.6.3.8 P P-type ATPase
MHPHHPDM_02751 1.9e-23 L Initiator Replication protein
MHPHHPDM_02753 6.2e-44 S Psort location CytoplasmicMembrane, score
MHPHHPDM_02754 2.1e-20 3.4.21.19 M Belongs to the peptidase S1B family
MHPHHPDM_02755 8.3e-17 S Protein of unknown function (DUF1093)
MHPHHPDM_02756 6.1e-55 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MHPHHPDM_02757 9e-33
MHPHHPDM_02758 3.7e-194 L Psort location Cytoplasmic, score
MHPHHPDM_02759 1.2e-129 3.1.21.3 V type I restriction modification DNA specificity domain protein
MHPHHPDM_02760 1.3e-301 hsdM 2.1.1.72 V type I restriction-modification system
MHPHHPDM_02761 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MHPHHPDM_02762 2.7e-10
MHPHHPDM_02763 7e-73
MHPHHPDM_02764 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
MHPHHPDM_02765 4e-281 1.3.5.4 C FAD binding domain
MHPHHPDM_02766 1.8e-159 K LysR substrate binding domain
MHPHHPDM_02767 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MHPHHPDM_02768 2.5e-289 yjcE P Sodium proton antiporter
MHPHHPDM_02769 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MHPHHPDM_02770 8.1e-117 K Bacterial regulatory proteins, tetR family
MHPHHPDM_02771 3.1e-51 NU Mycoplasma protein of unknown function, DUF285
MHPHHPDM_02772 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
MHPHHPDM_02773 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
MHPHHPDM_02774 1.4e-161 malD P ABC transporter permease
MHPHHPDM_02775 1.6e-149 malA S maltodextrose utilization protein MalA
MHPHHPDM_02776 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
MHPHHPDM_02777 4e-209 msmK P Belongs to the ABC transporter superfamily
MHPHHPDM_02778 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MHPHHPDM_02779 0.0 3.2.1.96 G Glycosyl hydrolase family 85
MHPHHPDM_02780 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MHPHHPDM_02781 2.3e-270 G Major Facilitator
MHPHHPDM_02782 1.1e-173 K Transcriptional regulator, LacI family
MHPHHPDM_02783 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
MHPHHPDM_02784 3.8e-159 licT K CAT RNA binding domain
MHPHHPDM_02785 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
MHPHHPDM_02786 5.5e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MHPHHPDM_02787 7.3e-86 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MHPHHPDM_02788 0.0 pepN 3.4.11.2 E aminopeptidase
MHPHHPDM_02789 1.1e-101 G Glycogen debranching enzyme
MHPHHPDM_02790 3.4e-10 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MHPHHPDM_02791 1.5e-154 yjdB S Domain of unknown function (DUF4767)
MHPHHPDM_02792 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
MHPHHPDM_02793 5.3e-72 asp2 S Asp23 family, cell envelope-related function
MHPHHPDM_02794 8.7e-72 asp S Asp23 family, cell envelope-related function
MHPHHPDM_02795 7.2e-23
MHPHHPDM_02796 4.4e-84
MHPHHPDM_02797 7.1e-37 S Transglycosylase associated protein
MHPHHPDM_02798 0.0 XK27_09800 I Acyltransferase family
MHPHHPDM_02799 1.1e-36 S MORN repeat
MHPHHPDM_02800 4.6e-25 S Cysteine-rich secretory protein family
MHPHHPDM_02801 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
MHPHHPDM_02802 1.4e-77
MHPHHPDM_02803 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
MHPHHPDM_02804 3.3e-97 FG HIT domain
MHPHHPDM_02805 1.7e-173 S Aldo keto reductase
MHPHHPDM_02806 1.9e-52 yitW S Pfam:DUF59
MHPHHPDM_02807 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MHPHHPDM_02808 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MHPHHPDM_02809 5e-195 blaA6 V Beta-lactamase
MHPHHPDM_02810 6.2e-96 V VanZ like family
MHPHHPDM_02811 1.7e-101 S WxL domain surface cell wall-binding
MHPHHPDM_02812 3.6e-183 S Cell surface protein
MHPHHPDM_02813 8.4e-75
MHPHHPDM_02814 8.4e-263
MHPHHPDM_02815 2.3e-227 hpk9 2.7.13.3 T GHKL domain
MHPHHPDM_02816 2.9e-38 S TfoX C-terminal domain
MHPHHPDM_02817 6e-140 K Helix-turn-helix domain
MHPHHPDM_02818 2.2e-126
MHPHHPDM_02819 1.1e-184 S DUF218 domain
MHPHHPDM_02820 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MHPHHPDM_02821 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
MHPHHPDM_02822 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MHPHHPDM_02823 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MHPHHPDM_02824 2.1e-31
MHPHHPDM_02825 1.7e-43 ankB S ankyrin repeats
MHPHHPDM_02826 6.5e-91 S ECF-type riboflavin transporter, S component
MHPHHPDM_02827 4.2e-47
MHPHHPDM_02828 9.8e-214 yceI EGP Major facilitator Superfamily
MHPHHPDM_02829 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
MHPHHPDM_02830 3.8e-23
MHPHHPDM_02832 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_02833 8.2e-173 ykfC 3.4.14.13 M NlpC/P60 family
MHPHHPDM_02834 3.3e-80 K AsnC family
MHPHHPDM_02835 2e-35
MHPHHPDM_02836 3.3e-33
MHPHHPDM_02837 5.6e-217 2.7.7.65 T diguanylate cyclase
MHPHHPDM_02838 2.8e-88
MHPHHPDM_02839 2.9e-176 L Initiator Replication protein
MHPHHPDM_02840 2.5e-29
MHPHHPDM_02841 2.3e-107 L Integrase
MHPHHPDM_02842 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
MHPHHPDM_02843 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHPHHPDM_02844 0.0 ybfG M peptidoglycan-binding domain-containing protein
MHPHHPDM_02847 2.6e-169 EG EamA-like transporter family
MHPHHPDM_02848 2.3e-38 gcvR T Belongs to the UPF0237 family
MHPHHPDM_02849 3e-243 XK27_08635 S UPF0210 protein
MHPHHPDM_02850 1.6e-134 K response regulator
MHPHHPDM_02851 2.9e-287 yclK 2.7.13.3 T Histidine kinase
MHPHHPDM_02852 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
MHPHHPDM_02853 9.7e-155 glcU U sugar transport
MHPHHPDM_02854 1.6e-67 M Cna protein B-type domain
MHPHHPDM_02855 3.2e-256 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MHPHHPDM_02856 1.8e-309 traA L MobA MobL family protein
MHPHHPDM_02857 3e-25
MHPHHPDM_02858 6.2e-32
MHPHHPDM_02859 9e-14 Q Methyltransferase
MHPHHPDM_02860 7.6e-110 XK27_07075 V CAAX protease self-immunity
MHPHHPDM_02861 1.1e-56 hxlR K HxlR-like helix-turn-helix
MHPHHPDM_02862 1.5e-129 L Helix-turn-helix domain
MHPHHPDM_02863 1.7e-159 L hmm pf00665
MHPHHPDM_02864 6.7e-232 EGP Major facilitator Superfamily
MHPHHPDM_02867 1.5e-42 S COG NOG38524 non supervised orthologous group
MHPHHPDM_02868 2.1e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MHPHHPDM_02869 3.6e-100 dhaL 2.7.1.121 S Dak2
MHPHHPDM_02870 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
MHPHHPDM_02871 4.7e-97 K Bacterial regulatory proteins, tetR family
MHPHHPDM_02872 5.1e-15
MHPHHPDM_02873 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MHPHHPDM_02874 3e-80 ydhK M Protein of unknown function (DUF1541)
MHPHHPDM_02875 8.3e-38 KT PspC domain protein
MHPHHPDM_02876 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MHPHHPDM_02877 2.8e-239 P Sodium:sulfate symporter transmembrane region
MHPHHPDM_02878 2.4e-301 1.3.5.4 C FMN_bind
MHPHHPDM_02879 5.4e-132 K LysR family
MHPHHPDM_02880 7.9e-60 mleR K LysR substrate binding domain
MHPHHPDM_02881 2.2e-99 padR K Virulence activator alpha C-term
MHPHHPDM_02882 2.7e-79 T Universal stress protein family
MHPHHPDM_02883 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MHPHHPDM_02885 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
MHPHHPDM_02886 6.4e-46 M domain protein
MHPHHPDM_02887 6e-52 ykoF S YKOF-related Family
MHPHHPDM_02888 3.3e-11 glnA 6.3.1.2 E glutamine synthetase
MHPHHPDM_02889 1.5e-193 glnA 6.3.1.2 E glutamine synthetase
MHPHHPDM_02890 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MHPHHPDM_02891 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
MHPHHPDM_02892 2.3e-107 L Integrase
MHPHHPDM_02893 4.9e-16
MHPHHPDM_02894 0.0 rafA 3.2.1.22 G alpha-galactosidase
MHPHHPDM_02895 9.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MHPHHPDM_02896 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MHPHHPDM_02898 2.9e-38 sirR K Helix-turn-helix diphteria tox regulatory element
MHPHHPDM_02899 1.5e-249 mntH P H( )-stimulated, divalent metal cation uptake system
MHPHHPDM_02900 6.2e-57 T Belongs to the universal stress protein A family
MHPHHPDM_02901 1e-96 tnpR1 L Resolvase, N terminal domain
MHPHHPDM_02902 2.2e-75 K Copper transport repressor CopY TcrY
MHPHHPDM_02903 0.0 copB 3.6.3.4 P P-type ATPase
MHPHHPDM_02904 2.8e-117 mdt(A) EGP Major facilitator Superfamily
MHPHHPDM_02905 1.3e-117
MHPHHPDM_02906 1.5e-65
MHPHHPDM_02907 1.5e-65 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MHPHHPDM_02908 4.5e-238 asdA 4.1.1.12 E Aminotransferase class I and II
MHPHHPDM_02909 1.2e-198 aspT U Predicted Permease Membrane Region
MHPHHPDM_02911 4.7e-25
MHPHHPDM_02912 0.0 mco Q Multicopper oxidase
MHPHHPDM_02913 3e-238 EGP Major Facilitator Superfamily
MHPHHPDM_02914 1.9e-54
MHPHHPDM_02915 7.4e-57 L Transposase IS66 family
MHPHHPDM_02916 1.5e-194 pbuX F xanthine permease
MHPHHPDM_02917 3.7e-24
MHPHHPDM_02918 1.9e-56 XK27_01125 L PFAM IS66 Orf2 family protein
MHPHHPDM_02919 8e-18
MHPHHPDM_02920 5.5e-18
MHPHHPDM_02921 1.2e-123 repA S Replication initiator protein A
MHPHHPDM_02922 6.7e-246 cycA E Amino acid permease
MHPHHPDM_02925 5.2e-34
MHPHHPDM_02926 4.2e-144 soj D AAA domain
MHPHHPDM_02927 4.9e-38 KT Transcriptional regulatory protein, C terminal
MHPHHPDM_02928 0.0 kup P Transport of potassium into the cell
MHPHHPDM_02929 7.6e-55 K helix_turn_helix multiple antibiotic resistance protein
MHPHHPDM_02930 2.3e-53 XK27_02070 S Nitroreductase
MHPHHPDM_02931 0.0 lacS G Transporter
MHPHHPDM_02932 1.9e-136 bgaR K helix_turn_helix, arabinose operon control protein
MHPHHPDM_02933 9.1e-153 cjaA ET ABC transporter substrate-binding protein
MHPHHPDM_02934 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MHPHHPDM_02935 4.3e-113 P ABC transporter permease
MHPHHPDM_02936 4.2e-113 papP P ABC transporter, permease protein
MHPHHPDM_02938 2.6e-47 S Family of unknown function (DUF5388)
MHPHHPDM_02939 1.6e-146 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MHPHHPDM_02940 2.8e-220 EGP Major facilitator Superfamily
MHPHHPDM_02941 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MHPHHPDM_02942 1.3e-14 3.3.1.1 H adenosylhomocysteinase activity
MHPHHPDM_02943 8e-68 C lyase activity
MHPHHPDM_02944 2e-184 L Psort location Cytoplasmic, score
MHPHHPDM_02945 1.7e-18
MHPHHPDM_02947 2.6e-40
MHPHHPDM_02948 1.2e-26
MHPHHPDM_02949 4.8e-94 K Bacterial regulatory proteins, tetR family
MHPHHPDM_02950 1.2e-191 1.1.1.219 GM Male sterility protein
MHPHHPDM_02951 1.6e-100 S Protein of unknown function (DUF1211)
MHPHHPDM_02952 2.7e-27 hol S Bacteriophage holin
MHPHHPDM_02953 3.3e-61 V Abortive infection bacteriophage resistance protein
MHPHHPDM_02954 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
MHPHHPDM_02955 5.7e-86
MHPHHPDM_02956 1.2e-40
MHPHHPDM_02957 7.9e-26
MHPHHPDM_02958 2.9e-125 S Phage Mu protein F like protein
MHPHHPDM_02959 1.2e-12 ytgB S Transglycosylase associated protein
MHPHHPDM_02960 8.8e-95 L 4.5 Transposon and IS
MHPHHPDM_02961 1.6e-39 L Transposase
MHPHHPDM_02963 6.6e-136 L Replication protein
MHPHHPDM_02964 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MHPHHPDM_02965 1.5e-15 S Alpha/beta hydrolase of unknown function (DUF915)
MHPHHPDM_02966 1.2e-23 S Family of unknown function (DUF5388)
MHPHHPDM_02967 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MHPHHPDM_02968 2.1e-11
MHPHHPDM_02969 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MHPHHPDM_02970 5.2e-25
MHPHHPDM_02971 2.6e-40
MHPHHPDM_02972 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
MHPHHPDM_02973 3.7e-31 tnp2PF3 L manually curated
MHPHHPDM_02974 4.2e-150 S Uncharacterised protein, DegV family COG1307
MHPHHPDM_02975 7e-57
MHPHHPDM_02976 6e-31 cspA K Cold shock protein
MHPHHPDM_02977 3.8e-40
MHPHHPDM_02978 4e-151 glcU U sugar transport
MHPHHPDM_02979 2.8e-221 L Transposase
MHPHHPDM_02980 1.8e-159 lys M Glycosyl hydrolases family 25
MHPHHPDM_02981 1.2e-103
MHPHHPDM_02982 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
MHPHHPDM_02983 4.4e-127 terC P integral membrane protein, YkoY family
MHPHHPDM_02985 3.1e-36 L Resolvase, N terminal domain
MHPHHPDM_02986 1.2e-163 L PFAM Integrase catalytic region
MHPHHPDM_02987 4.8e-58
MHPHHPDM_02988 4.2e-70 S Pyrimidine dimer DNA glycosylase
MHPHHPDM_02989 1.3e-23 hol S Bacteriophage holin
MHPHHPDM_02990 3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MHPHHPDM_02991 5.4e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MHPHHPDM_02993 2.9e-13
MHPHHPDM_02995 1.7e-88 L Helix-turn-helix domain
MHPHHPDM_02996 1.7e-90 L Transposase and inactivated derivatives, IS30 family
MHPHHPDM_02997 4.6e-82 tnp2PF3 L Transposase DDE domain
MHPHHPDM_02998 1.7e-81 tnp L DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)