ORF_ID e_value Gene_name EC_number CAZy COGs Description
COGOJKHO_00001 1.4e-78 K Acetyltransferase (GNAT) domain
COGOJKHO_00002 5.1e-209 mccF V LD-carboxypeptidase
COGOJKHO_00003 2.8e-241 M Glycosyltransferase, group 2 family protein
COGOJKHO_00004 1.7e-72 S SnoaL-like domain
COGOJKHO_00005 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
COGOJKHO_00006 6.1e-244 P Major Facilitator Superfamily
COGOJKHO_00007 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_00008 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
COGOJKHO_00010 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
COGOJKHO_00011 8.3e-110 ypsA S Belongs to the UPF0398 family
COGOJKHO_00012 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
COGOJKHO_00013 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
COGOJKHO_00014 7e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
COGOJKHO_00015 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
COGOJKHO_00016 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
COGOJKHO_00017 4.4e-83 uspA T Universal stress protein family
COGOJKHO_00018 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
COGOJKHO_00019 2e-99 metI P ABC transporter permease
COGOJKHO_00020 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COGOJKHO_00022 1.1e-127 dnaD L Replication initiation and membrane attachment
COGOJKHO_00023 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COGOJKHO_00024 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
COGOJKHO_00025 2.1e-72 ypmB S protein conserved in bacteria
COGOJKHO_00026 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
COGOJKHO_00027 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
COGOJKHO_00028 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
COGOJKHO_00029 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
COGOJKHO_00030 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
COGOJKHO_00031 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COGOJKHO_00032 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COGOJKHO_00033 2.5e-250 malT G Major Facilitator
COGOJKHO_00034 1.5e-89 S Domain of unknown function (DUF4767)
COGOJKHO_00035 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
COGOJKHO_00036 1.2e-149 yitU 3.1.3.104 S hydrolase
COGOJKHO_00037 1.4e-265 yfnA E Amino Acid
COGOJKHO_00038 3.3e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
COGOJKHO_00039 2.4e-43
COGOJKHO_00040 1.9e-49
COGOJKHO_00041 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
COGOJKHO_00042 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
COGOJKHO_00043 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
COGOJKHO_00044 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
COGOJKHO_00045 8.6e-281 pipD E Dipeptidase
COGOJKHO_00046 9.4e-40
COGOJKHO_00047 4.8e-29 S CsbD-like
COGOJKHO_00048 6.5e-41 S transglycosylase associated protein
COGOJKHO_00049 3.1e-14
COGOJKHO_00050 2.9e-35
COGOJKHO_00051 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
COGOJKHO_00052 1e-65 S Protein of unknown function (DUF805)
COGOJKHO_00053 6.3e-76 uspA T Belongs to the universal stress protein A family
COGOJKHO_00054 1.9e-67 tspO T TspO/MBR family
COGOJKHO_00055 7.9e-41
COGOJKHO_00056 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
COGOJKHO_00057 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
COGOJKHO_00058 2.3e-29 L hmm pf00665
COGOJKHO_00059 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COGOJKHO_00060 1.3e-28
COGOJKHO_00061 8.5e-54
COGOJKHO_00062 1.2e-139 f42a O Band 7 protein
COGOJKHO_00063 1.4e-301 norB EGP Major Facilitator
COGOJKHO_00064 7.5e-92 K transcriptional regulator
COGOJKHO_00065 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COGOJKHO_00066 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
COGOJKHO_00067 1.6e-160 K LysR substrate binding domain
COGOJKHO_00068 2.2e-123 S Protein of unknown function (DUF554)
COGOJKHO_00069 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
COGOJKHO_00070 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
COGOJKHO_00071 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
COGOJKHO_00072 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COGOJKHO_00073 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
COGOJKHO_00074 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
COGOJKHO_00075 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COGOJKHO_00076 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
COGOJKHO_00077 2.1e-126 IQ reductase
COGOJKHO_00078 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
COGOJKHO_00079 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COGOJKHO_00080 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COGOJKHO_00081 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
COGOJKHO_00082 1.1e-178 yneE K Transcriptional regulator
COGOJKHO_00083 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COGOJKHO_00085 2.1e-58 S Protein of unknown function (DUF1648)
COGOJKHO_00086 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COGOJKHO_00087 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
COGOJKHO_00088 5.8e-217 E glutamate:sodium symporter activity
COGOJKHO_00089 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
COGOJKHO_00090 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
COGOJKHO_00091 2e-97 entB 3.5.1.19 Q Isochorismatase family
COGOJKHO_00092 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
COGOJKHO_00093 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
COGOJKHO_00094 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
COGOJKHO_00095 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
COGOJKHO_00096 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
COGOJKHO_00097 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
COGOJKHO_00098 5.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
COGOJKHO_00100 1.5e-270 XK27_00765
COGOJKHO_00101 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
COGOJKHO_00102 5.3e-86
COGOJKHO_00103 6.4e-156 pelX UW LPXTG-motif cell wall anchor domain protein
COGOJKHO_00104 6.8e-53
COGOJKHO_00105 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
COGOJKHO_00106 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
COGOJKHO_00107 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
COGOJKHO_00108 2.6e-39 ylqC S Belongs to the UPF0109 family
COGOJKHO_00109 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
COGOJKHO_00110 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
COGOJKHO_00111 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
COGOJKHO_00112 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
COGOJKHO_00113 0.0 smc D Required for chromosome condensation and partitioning
COGOJKHO_00114 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
COGOJKHO_00115 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
COGOJKHO_00116 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
COGOJKHO_00117 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
COGOJKHO_00118 0.0 yloV S DAK2 domain fusion protein YloV
COGOJKHO_00119 1.8e-57 asp S Asp23 family, cell envelope-related function
COGOJKHO_00120 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
COGOJKHO_00121 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
COGOJKHO_00122 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
COGOJKHO_00123 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
COGOJKHO_00124 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
COGOJKHO_00125 1.7e-134 stp 3.1.3.16 T phosphatase
COGOJKHO_00126 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
COGOJKHO_00127 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
COGOJKHO_00128 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
COGOJKHO_00129 8.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
COGOJKHO_00130 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
COGOJKHO_00131 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
COGOJKHO_00132 4.5e-55
COGOJKHO_00133 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
COGOJKHO_00134 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COGOJKHO_00135 1.2e-104 opuCB E ABC transporter permease
COGOJKHO_00136 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
COGOJKHO_00137 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
COGOJKHO_00138 2.2e-76 argR K Regulates arginine biosynthesis genes
COGOJKHO_00139 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
COGOJKHO_00140 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COGOJKHO_00141 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COGOJKHO_00142 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
COGOJKHO_00143 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
COGOJKHO_00144 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
COGOJKHO_00145 3.5e-74 yqhY S Asp23 family, cell envelope-related function
COGOJKHO_00146 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
COGOJKHO_00147 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COGOJKHO_00148 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
COGOJKHO_00149 3.2e-53 ysxB J Cysteine protease Prp
COGOJKHO_00150 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
COGOJKHO_00151 1.8e-89 K Transcriptional regulator
COGOJKHO_00152 5.4e-19
COGOJKHO_00155 1.7e-30
COGOJKHO_00156 5.3e-56
COGOJKHO_00157 2.4e-98 dut S Protein conserved in bacteria
COGOJKHO_00158 4e-181
COGOJKHO_00159 2e-161
COGOJKHO_00160 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
COGOJKHO_00161 4.6e-64 glnR K Transcriptional regulator
COGOJKHO_00162 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
COGOJKHO_00163 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
COGOJKHO_00164 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
COGOJKHO_00165 4.4e-68 yqhL P Rhodanese-like protein
COGOJKHO_00166 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
COGOJKHO_00167 5.7e-180 glk 2.7.1.2 G Glucokinase
COGOJKHO_00168 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
COGOJKHO_00169 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
COGOJKHO_00170 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
COGOJKHO_00171 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COGOJKHO_00172 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
COGOJKHO_00173 0.0 S membrane
COGOJKHO_00174 1.5e-54 yneR S Belongs to the HesB IscA family
COGOJKHO_00175 4e-75 XK27_02470 K LytTr DNA-binding domain
COGOJKHO_00176 2.3e-96 liaI S membrane
COGOJKHO_00177 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COGOJKHO_00178 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
COGOJKHO_00179 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
COGOJKHO_00180 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COGOJKHO_00181 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
COGOJKHO_00182 1.1e-62 yodB K Transcriptional regulator, HxlR family
COGOJKHO_00183 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
COGOJKHO_00184 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COGOJKHO_00185 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
COGOJKHO_00186 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COGOJKHO_00187 9.3e-93 S SdpI/YhfL protein family
COGOJKHO_00188 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
COGOJKHO_00189 0.0 sbcC L Putative exonuclease SbcCD, C subunit
COGOJKHO_00190 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COGOJKHO_00191 8e-307 arlS 2.7.13.3 T Histidine kinase
COGOJKHO_00192 4.3e-121 K response regulator
COGOJKHO_00193 1.2e-244 rarA L recombination factor protein RarA
COGOJKHO_00194 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
COGOJKHO_00195 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COGOJKHO_00196 7e-88 S Peptidase propeptide and YPEB domain
COGOJKHO_00197 1.6e-97 yceD S Uncharacterized ACR, COG1399
COGOJKHO_00198 3.4e-219 ylbM S Belongs to the UPF0348 family
COGOJKHO_00199 4.4e-140 yqeM Q Methyltransferase
COGOJKHO_00200 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COGOJKHO_00201 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
COGOJKHO_00202 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
COGOJKHO_00203 1.1e-50 yhbY J RNA-binding protein
COGOJKHO_00204 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
COGOJKHO_00205 1.4e-98 yqeG S HAD phosphatase, family IIIA
COGOJKHO_00206 1.3e-79
COGOJKHO_00207 6.9e-222 pgaC GT2 M Glycosyl transferase
COGOJKHO_00208 2.2e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
COGOJKHO_00209 1e-62 hxlR K Transcriptional regulator, HxlR family
COGOJKHO_00210 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
COGOJKHO_00211 5e-240 yrvN L AAA C-terminal domain
COGOJKHO_00212 1.1e-55
COGOJKHO_00213 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
COGOJKHO_00214 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
COGOJKHO_00215 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
COGOJKHO_00216 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
COGOJKHO_00217 1.2e-171 dnaI L Primosomal protein DnaI
COGOJKHO_00218 1.1e-248 dnaB L replication initiation and membrane attachment
COGOJKHO_00219 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
COGOJKHO_00220 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
COGOJKHO_00221 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
COGOJKHO_00222 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
COGOJKHO_00223 4.5e-121 ybhL S Belongs to the BI1 family
COGOJKHO_00224 3.1e-111 hipB K Helix-turn-helix
COGOJKHO_00225 5.5e-45 yitW S Iron-sulfur cluster assembly protein
COGOJKHO_00226 1.4e-272 sufB O assembly protein SufB
COGOJKHO_00227 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
COGOJKHO_00228 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
COGOJKHO_00229 2.6e-244 sufD O FeS assembly protein SufD
COGOJKHO_00230 4.2e-144 sufC O FeS assembly ATPase SufC
COGOJKHO_00231 1.3e-34 feoA P FeoA domain
COGOJKHO_00232 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
COGOJKHO_00233 7.9e-21 S Virus attachment protein p12 family
COGOJKHO_00234 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
COGOJKHO_00235 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
COGOJKHO_00236 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
COGOJKHO_00237 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
COGOJKHO_00238 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
COGOJKHO_00239 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
COGOJKHO_00240 6.2e-224 ecsB U ABC transporter
COGOJKHO_00241 1.6e-134 ecsA V ABC transporter, ATP-binding protein
COGOJKHO_00242 9.9e-82 hit FG histidine triad
COGOJKHO_00243 2e-42
COGOJKHO_00244 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COGOJKHO_00245 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
COGOJKHO_00246 3.5e-78 S WxL domain surface cell wall-binding
COGOJKHO_00247 4e-103 S WxL domain surface cell wall-binding
COGOJKHO_00248 9.3e-192 S Fn3-like domain
COGOJKHO_00249 3.5e-61
COGOJKHO_00250 0.0
COGOJKHO_00251 2.1e-241 npr 1.11.1.1 C NADH oxidase
COGOJKHO_00253 3.9e-162 K Transcriptional regulator
COGOJKHO_00254 1.1e-161 akr5f 1.1.1.346 S reductase
COGOJKHO_00255 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
COGOJKHO_00256 8.7e-78 K Winged helix DNA-binding domain
COGOJKHO_00257 6.4e-268 ycaM E amino acid
COGOJKHO_00258 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
COGOJKHO_00259 2.7e-32
COGOJKHO_00260 4.1e-283 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
COGOJKHO_00261 6.2e-149 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
COGOJKHO_00262 0.0 M Bacterial Ig-like domain (group 3)
COGOJKHO_00263 4.2e-77 fld C Flavodoxin
COGOJKHO_00264 6.5e-232
COGOJKHO_00265 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
COGOJKHO_00266 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
COGOJKHO_00267 1.4e-151 EG EamA-like transporter family
COGOJKHO_00268 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COGOJKHO_00269 9.8e-152 S hydrolase
COGOJKHO_00270 1.8e-81
COGOJKHO_00271 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COGOJKHO_00272 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
COGOJKHO_00273 9.9e-129 gntR K UTRA
COGOJKHO_00274 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_00275 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
COGOJKHO_00276 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_00277 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_00278 4.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
COGOJKHO_00279 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
COGOJKHO_00280 1.1e-151 V ABC transporter
COGOJKHO_00281 2.8e-117 K Transcriptional regulator
COGOJKHO_00282 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COGOJKHO_00283 3.6e-88 niaR S 3H domain
COGOJKHO_00284 2.1e-232 S Sterol carrier protein domain
COGOJKHO_00285 1.4e-211 S Bacterial protein of unknown function (DUF871)
COGOJKHO_00286 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
COGOJKHO_00287 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
COGOJKHO_00288 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
COGOJKHO_00289 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
COGOJKHO_00290 2.5e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COGOJKHO_00291 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
COGOJKHO_00292 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
COGOJKHO_00293 1.1e-281 thrC 4.2.3.1 E Threonine synthase
COGOJKHO_00294 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
COGOJKHO_00296 1.5e-52
COGOJKHO_00297 5.4e-118
COGOJKHO_00298 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
COGOJKHO_00299 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
COGOJKHO_00301 3.2e-50
COGOJKHO_00302 1.1e-88
COGOJKHO_00303 5.5e-71 gtcA S Teichoic acid glycosylation protein
COGOJKHO_00304 4e-34
COGOJKHO_00305 1.9e-80 uspA T universal stress protein
COGOJKHO_00306 6.9e-164 V ABC transporter, ATP-binding protein
COGOJKHO_00307 7.9e-61 gntR1 K Transcriptional regulator, GntR family
COGOJKHO_00308 7.4e-40
COGOJKHO_00309 0.0 V FtsX-like permease family
COGOJKHO_00310 1.7e-139 cysA V ABC transporter, ATP-binding protein
COGOJKHO_00311 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
COGOJKHO_00312 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_00313 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
COGOJKHO_00314 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
COGOJKHO_00315 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
COGOJKHO_00316 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
COGOJKHO_00317 4.3e-223 XK27_09615 1.3.5.4 S reductase
COGOJKHO_00318 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
COGOJKHO_00319 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
COGOJKHO_00320 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
COGOJKHO_00321 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COGOJKHO_00322 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COGOJKHO_00323 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
COGOJKHO_00324 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
COGOJKHO_00325 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
COGOJKHO_00326 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
COGOJKHO_00327 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
COGOJKHO_00328 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
COGOJKHO_00329 1e-122 2.1.1.14 E Methionine synthase
COGOJKHO_00330 9.2e-253 pgaC GT2 M Glycosyl transferase
COGOJKHO_00331 2.6e-94
COGOJKHO_00332 6.5e-156 T EAL domain
COGOJKHO_00333 5.6e-161 GM NmrA-like family
COGOJKHO_00334 2.4e-221 pbuG S Permease family
COGOJKHO_00335 2.7e-236 pbuX F xanthine permease
COGOJKHO_00336 1e-298 pucR QT Purine catabolism regulatory protein-like family
COGOJKHO_00337 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COGOJKHO_00338 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
COGOJKHO_00339 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
COGOJKHO_00340 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COGOJKHO_00341 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COGOJKHO_00342 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
COGOJKHO_00343 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
COGOJKHO_00344 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
COGOJKHO_00345 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
COGOJKHO_00346 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
COGOJKHO_00347 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
COGOJKHO_00348 8.2e-96 wecD K Acetyltransferase (GNAT) family
COGOJKHO_00349 5.6e-115 ylbE GM NAD(P)H-binding
COGOJKHO_00350 7.3e-161 mleR K LysR family
COGOJKHO_00351 1.7e-126 S membrane transporter protein
COGOJKHO_00352 3e-18
COGOJKHO_00353 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COGOJKHO_00354 5e-218 patA 2.6.1.1 E Aminotransferase
COGOJKHO_00355 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
COGOJKHO_00356 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
COGOJKHO_00357 8.5e-57 S SdpI/YhfL protein family
COGOJKHO_00358 1.9e-127 C Zinc-binding dehydrogenase
COGOJKHO_00359 3e-30 C Zinc-binding dehydrogenase
COGOJKHO_00360 5e-63 K helix_turn_helix, mercury resistance
COGOJKHO_00361 2.8e-213 yttB EGP Major facilitator Superfamily
COGOJKHO_00362 2.9e-269 yjcE P Sodium proton antiporter
COGOJKHO_00363 4.9e-87 nrdI F Belongs to the NrdI family
COGOJKHO_00364 1.2e-239 yhdP S Transporter associated domain
COGOJKHO_00365 4.4e-58
COGOJKHO_00366 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
COGOJKHO_00367 7.7e-61
COGOJKHO_00368 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
COGOJKHO_00369 5.5e-138 rrp8 K LytTr DNA-binding domain
COGOJKHO_00370 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COGOJKHO_00371 1.5e-138
COGOJKHO_00372 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
COGOJKHO_00373 2.4e-130 gntR2 K Transcriptional regulator
COGOJKHO_00374 2.3e-164 S Putative esterase
COGOJKHO_00375 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COGOJKHO_00376 2.3e-223 lsgC M Glycosyl transferases group 1
COGOJKHO_00377 3.3e-21 S Protein of unknown function (DUF2929)
COGOJKHO_00378 1.7e-48 K Cro/C1-type HTH DNA-binding domain
COGOJKHO_00379 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COGOJKHO_00380 1.6e-79 uspA T universal stress protein
COGOJKHO_00381 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
COGOJKHO_00382 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
COGOJKHO_00383 4e-60
COGOJKHO_00384 3.7e-73
COGOJKHO_00385 5e-82 yybC S Protein of unknown function (DUF2798)
COGOJKHO_00386 1.7e-45
COGOJKHO_00387 5.2e-47
COGOJKHO_00388 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
COGOJKHO_00389 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
COGOJKHO_00390 8.4e-145 yjfP S Dienelactone hydrolase family
COGOJKHO_00391 9.8e-28
COGOJKHO_00392 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COGOJKHO_00393 6.5e-47
COGOJKHO_00394 1.3e-57
COGOJKHO_00395 2.3e-164
COGOJKHO_00396 1.3e-72 K Transcriptional regulator
COGOJKHO_00397 0.0 pepF2 E Oligopeptidase F
COGOJKHO_00398 3.8e-173 D Alpha beta
COGOJKHO_00399 1.2e-45 S Enterocin A Immunity
COGOJKHO_00400 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
COGOJKHO_00401 8.7e-125 skfE V ABC transporter
COGOJKHO_00402 2.7e-132
COGOJKHO_00403 3.7e-107 pncA Q Isochorismatase family
COGOJKHO_00404 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
COGOJKHO_00405 0.0 yjcE P Sodium proton antiporter
COGOJKHO_00406 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
COGOJKHO_00407 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
COGOJKHO_00408 1.1e-116 K Helix-turn-helix domain, rpiR family
COGOJKHO_00409 2.3e-157 ccpB 5.1.1.1 K lacI family
COGOJKHO_00410 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
COGOJKHO_00411 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COGOJKHO_00412 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
COGOJKHO_00413 1.2e-97 drgA C Nitroreductase family
COGOJKHO_00414 3.6e-168 S Polyphosphate kinase 2 (PPK2)
COGOJKHO_00415 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_00416 3.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
COGOJKHO_00417 0.0 glpQ 3.1.4.46 C phosphodiesterase
COGOJKHO_00418 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COGOJKHO_00419 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
COGOJKHO_00420 3.9e-219 M domain protein
COGOJKHO_00421 1.5e-41 M domain protein
COGOJKHO_00422 0.0 ydgH S MMPL family
COGOJKHO_00423 2.6e-112 S Protein of unknown function (DUF1211)
COGOJKHO_00424 3.7e-34
COGOJKHO_00425 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COGOJKHO_00426 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
COGOJKHO_00427 8.6e-98 J glyoxalase III activity
COGOJKHO_00428 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
COGOJKHO_00429 5.9e-91 rmeB K transcriptional regulator, MerR family
COGOJKHO_00430 2.1e-55 S Domain of unknown function (DU1801)
COGOJKHO_00431 7.6e-166 corA P CorA-like Mg2+ transporter protein
COGOJKHO_00432 4.6e-216 ysaA V RDD family
COGOJKHO_00433 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
COGOJKHO_00434 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
COGOJKHO_00435 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
COGOJKHO_00436 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
COGOJKHO_00437 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
COGOJKHO_00438 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COGOJKHO_00439 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
COGOJKHO_00440 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
COGOJKHO_00441 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
COGOJKHO_00442 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
COGOJKHO_00443 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
COGOJKHO_00444 3.1e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COGOJKHO_00445 3.1e-136 terC P membrane
COGOJKHO_00446 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
COGOJKHO_00447 5.7e-258 npr 1.11.1.1 C NADH oxidase
COGOJKHO_00448 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
COGOJKHO_00449 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
COGOJKHO_00450 3.1e-176 XK27_08835 S ABC transporter
COGOJKHO_00451 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
COGOJKHO_00452 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
COGOJKHO_00453 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
COGOJKHO_00454 5e-162 degV S Uncharacterised protein, DegV family COG1307
COGOJKHO_00455 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
COGOJKHO_00456 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
COGOJKHO_00457 6e-39
COGOJKHO_00458 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
COGOJKHO_00459 2e-106 3.2.2.20 K acetyltransferase
COGOJKHO_00460 7.8e-296 S ABC transporter, ATP-binding protein
COGOJKHO_00461 7.5e-49 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_00462 1.2e-14 K Bacterial regulatory proteins, tetR family
COGOJKHO_00463 4.7e-214 S membrane
COGOJKHO_00464 9.2e-82 K Bacterial regulatory proteins, tetR family
COGOJKHO_00465 0.0 CP_1020 S Zinc finger, swim domain protein
COGOJKHO_00466 2e-112 GM epimerase
COGOJKHO_00467 4.1e-68 S Protein of unknown function (DUF1722)
COGOJKHO_00468 9.1e-71 yneH 1.20.4.1 P ArsC family
COGOJKHO_00469 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
COGOJKHO_00470 8e-137 K DeoR C terminal sensor domain
COGOJKHO_00471 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COGOJKHO_00472 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COGOJKHO_00473 4.3e-77 K Transcriptional regulator
COGOJKHO_00474 2.2e-241 EGP Major facilitator Superfamily
COGOJKHO_00475 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COGOJKHO_00476 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
COGOJKHO_00477 2.2e-179 C Zinc-binding dehydrogenase
COGOJKHO_00478 1.5e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
COGOJKHO_00479 1.7e-207
COGOJKHO_00480 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_00481 7.8e-61 P Rhodanese Homology Domain
COGOJKHO_00482 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
COGOJKHO_00483 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_00484 3.2e-167 drrA V ABC transporter
COGOJKHO_00485 2e-119 drrB U ABC-2 type transporter
COGOJKHO_00486 6.9e-223 M O-Antigen ligase
COGOJKHO_00487 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
COGOJKHO_00488 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
COGOJKHO_00489 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
COGOJKHO_00490 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COGOJKHO_00492 5.6e-29 S Protein of unknown function (DUF2929)
COGOJKHO_00493 0.0 dnaE 2.7.7.7 L DNA polymerase
COGOJKHO_00494 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
COGOJKHO_00495 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
COGOJKHO_00496 1.5e-74 yeaL S Protein of unknown function (DUF441)
COGOJKHO_00497 1.1e-169 cvfB S S1 domain
COGOJKHO_00498 1.1e-164 xerD D recombinase XerD
COGOJKHO_00499 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
COGOJKHO_00500 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
COGOJKHO_00501 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
COGOJKHO_00502 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COGOJKHO_00503 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
COGOJKHO_00504 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
COGOJKHO_00505 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
COGOJKHO_00506 2e-19 M Lysin motif
COGOJKHO_00507 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
COGOJKHO_00508 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
COGOJKHO_00509 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
COGOJKHO_00510 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
COGOJKHO_00511 2.1e-206 S Tetratricopeptide repeat protein
COGOJKHO_00512 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
COGOJKHO_00513 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
COGOJKHO_00514 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
COGOJKHO_00515 9.6e-85
COGOJKHO_00516 0.0 yfmR S ABC transporter, ATP-binding protein
COGOJKHO_00517 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
COGOJKHO_00518 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
COGOJKHO_00519 5.1e-148 DegV S EDD domain protein, DegV family
COGOJKHO_00520 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
COGOJKHO_00521 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
COGOJKHO_00522 3.4e-35 yozE S Belongs to the UPF0346 family
COGOJKHO_00523 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
COGOJKHO_00524 7.3e-251 emrY EGP Major facilitator Superfamily
COGOJKHO_00525 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
COGOJKHO_00526 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
COGOJKHO_00527 2.3e-173 L restriction endonuclease
COGOJKHO_00528 3.1e-170 cpsY K Transcriptional regulator, LysR family
COGOJKHO_00529 6.8e-228 XK27_05470 E Methionine synthase
COGOJKHO_00531 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
COGOJKHO_00532 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
COGOJKHO_00533 9.5e-158 dprA LU DNA protecting protein DprA
COGOJKHO_00534 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
COGOJKHO_00535 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
COGOJKHO_00536 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
COGOJKHO_00537 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
COGOJKHO_00538 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
COGOJKHO_00539 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
COGOJKHO_00540 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
COGOJKHO_00541 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COGOJKHO_00542 2.2e-111 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
COGOJKHO_00543 5.9e-177 K Transcriptional regulator
COGOJKHO_00544 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
COGOJKHO_00545 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
COGOJKHO_00546 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COGOJKHO_00547 4.2e-32 S YozE SAM-like fold
COGOJKHO_00548 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
COGOJKHO_00549 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COGOJKHO_00550 6.3e-246 M Glycosyl transferase family group 2
COGOJKHO_00551 1.8e-66
COGOJKHO_00552 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
COGOJKHO_00553 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_00554 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
COGOJKHO_00555 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGOJKHO_00556 9.9e-216 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGOJKHO_00557 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
COGOJKHO_00558 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
COGOJKHO_00559 5.1e-227
COGOJKHO_00560 4.6e-275 lldP C L-lactate permease
COGOJKHO_00561 4.1e-59
COGOJKHO_00562 3.5e-123
COGOJKHO_00563 3.2e-245 cycA E Amino acid permease
COGOJKHO_00564 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
COGOJKHO_00565 4.6e-129 yejC S Protein of unknown function (DUF1003)
COGOJKHO_00566 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
COGOJKHO_00567 4.6e-12
COGOJKHO_00568 1.6e-211 pmrB EGP Major facilitator Superfamily
COGOJKHO_00569 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
COGOJKHO_00570 1.4e-49
COGOJKHO_00571 1.6e-09
COGOJKHO_00572 2.9e-131 S Protein of unknown function (DUF975)
COGOJKHO_00573 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
COGOJKHO_00574 2.1e-160 degV S EDD domain protein, DegV family
COGOJKHO_00575 1.9e-66 K Transcriptional regulator
COGOJKHO_00576 0.0 FbpA K Fibronectin-binding protein
COGOJKHO_00577 9.3e-133 S ABC-2 family transporter protein
COGOJKHO_00578 5.4e-164 V ABC transporter, ATP-binding protein
COGOJKHO_00579 3e-92 3.6.1.55 F NUDIX domain
COGOJKHO_00580 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
COGOJKHO_00581 1.2e-69 S LuxR family transcriptional regulator
COGOJKHO_00582 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
COGOJKHO_00585 3.1e-71 frataxin S Domain of unknown function (DU1801)
COGOJKHO_00586 5.5e-112 pgm5 G Phosphoglycerate mutase family
COGOJKHO_00587 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COGOJKHO_00588 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
COGOJKHO_00589 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
COGOJKHO_00590 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
COGOJKHO_00591 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
COGOJKHO_00592 1.1e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
COGOJKHO_00593 2.2e-61 esbA S Family of unknown function (DUF5322)
COGOJKHO_00594 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
COGOJKHO_00595 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
COGOJKHO_00596 5.9e-146 S hydrolase activity, acting on ester bonds
COGOJKHO_00597 2.3e-193
COGOJKHO_00598 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
COGOJKHO_00599 1.3e-123
COGOJKHO_00600 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
COGOJKHO_00601 2.6e-239 M hydrolase, family 25
COGOJKHO_00602 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COGOJKHO_00603 3.3e-132 yliE T Putative diguanylate phosphodiesterase
COGOJKHO_00604 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
COGOJKHO_00605 1.1e-61 S Protein of unknown function (DUF3290)
COGOJKHO_00606 2e-109 yviA S Protein of unknown function (DUF421)
COGOJKHO_00607 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
COGOJKHO_00608 3.9e-270 nox C NADH oxidase
COGOJKHO_00609 1.9e-124 yliE T Putative diguanylate phosphodiesterase
COGOJKHO_00610 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
COGOJKHO_00611 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
COGOJKHO_00612 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
COGOJKHO_00613 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
COGOJKHO_00614 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
COGOJKHO_00615 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
COGOJKHO_00616 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
COGOJKHO_00617 3.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COGOJKHO_00618 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
COGOJKHO_00619 1.5e-155 pstA P Phosphate transport system permease protein PstA
COGOJKHO_00620 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
COGOJKHO_00621 2.1e-149 pstS P Phosphate
COGOJKHO_00622 3.5e-250 phoR 2.7.13.3 T Histidine kinase
COGOJKHO_00623 1.5e-132 K response regulator
COGOJKHO_00624 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
COGOJKHO_00625 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
COGOJKHO_00626 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
COGOJKHO_00627 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
COGOJKHO_00628 7.5e-126 comFC S Competence protein
COGOJKHO_00629 9.6e-258 comFA L Helicase C-terminal domain protein
COGOJKHO_00630 1.7e-114 yvyE 3.4.13.9 S YigZ family
COGOJKHO_00631 4.3e-145 pstS P Phosphate
COGOJKHO_00632 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
COGOJKHO_00633 0.0 ydaO E amino acid
COGOJKHO_00634 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
COGOJKHO_00635 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
COGOJKHO_00636 6.1e-109 ydiL S CAAX protease self-immunity
COGOJKHO_00637 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
COGOJKHO_00638 3.3e-307 uup S ABC transporter, ATP-binding protein
COGOJKHO_00639 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
COGOJKHO_00640 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
COGOJKHO_00641 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
COGOJKHO_00642 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
COGOJKHO_00643 5.1e-190 phnD P Phosphonate ABC transporter
COGOJKHO_00644 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
COGOJKHO_00645 2.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
COGOJKHO_00646 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
COGOJKHO_00647 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
COGOJKHO_00648 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
COGOJKHO_00649 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COGOJKHO_00650 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
COGOJKHO_00651 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
COGOJKHO_00652 1e-57 yabA L Involved in initiation control of chromosome replication
COGOJKHO_00653 3.3e-186 holB 2.7.7.7 L DNA polymerase III
COGOJKHO_00654 2.4e-53 yaaQ S Cyclic-di-AMP receptor
COGOJKHO_00655 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
COGOJKHO_00656 2.2e-38 yaaL S Protein of unknown function (DUF2508)
COGOJKHO_00657 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
COGOJKHO_00658 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
COGOJKHO_00659 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COGOJKHO_00660 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
COGOJKHO_00661 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
COGOJKHO_00662 6.5e-37 nrdH O Glutaredoxin
COGOJKHO_00663 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COGOJKHO_00664 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COGOJKHO_00665 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
COGOJKHO_00666 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COGOJKHO_00667 1.2e-38 L nuclease
COGOJKHO_00668 9.3e-178 F DNA/RNA non-specific endonuclease
COGOJKHO_00669 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
COGOJKHO_00670 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
COGOJKHO_00671 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
COGOJKHO_00672 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
COGOJKHO_00673 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_00674 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
COGOJKHO_00675 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
COGOJKHO_00676 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
COGOJKHO_00677 2.4e-101 sigH K Sigma-70 region 2
COGOJKHO_00678 7.7e-97 yacP S YacP-like NYN domain
COGOJKHO_00679 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
COGOJKHO_00680 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
COGOJKHO_00681 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
COGOJKHO_00682 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
COGOJKHO_00683 3.7e-205 yacL S domain protein
COGOJKHO_00684 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
COGOJKHO_00685 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
COGOJKHO_00686 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
COGOJKHO_00687 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
COGOJKHO_00688 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
COGOJKHO_00689 5.2e-113 zmp2 O Zinc-dependent metalloprotease
COGOJKHO_00690 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COGOJKHO_00691 8.3e-177 EG EamA-like transporter family
COGOJKHO_00692 5.6e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
COGOJKHO_00693 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COGOJKHO_00694 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
COGOJKHO_00695 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
COGOJKHO_00696 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
COGOJKHO_00697 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
COGOJKHO_00698 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
COGOJKHO_00699 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
COGOJKHO_00700 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
COGOJKHO_00701 0.0 levR K Sigma-54 interaction domain
COGOJKHO_00702 4.7e-64 S Domain of unknown function (DUF956)
COGOJKHO_00703 4.4e-169 manN G system, mannose fructose sorbose family IID component
COGOJKHO_00704 3.4e-133 manY G PTS system
COGOJKHO_00705 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
COGOJKHO_00706 7.4e-152 G Peptidase_C39 like family
COGOJKHO_00708 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
COGOJKHO_00709 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
COGOJKHO_00710 3.7e-81 ydcK S Belongs to the SprT family
COGOJKHO_00711 0.0 yhgF K Tex-like protein N-terminal domain protein
COGOJKHO_00712 3.4e-71
COGOJKHO_00713 0.0 pacL 3.6.3.8 P P-type ATPase
COGOJKHO_00714 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
COGOJKHO_00715 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
COGOJKHO_00716 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
COGOJKHO_00717 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
COGOJKHO_00718 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
COGOJKHO_00719 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
COGOJKHO_00720 1.6e-151 pnuC H nicotinamide mononucleotide transporter
COGOJKHO_00721 4.7e-194 ybiR P Citrate transporter
COGOJKHO_00722 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
COGOJKHO_00723 2.5e-53 S Cupin domain
COGOJKHO_00724 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
COGOJKHO_00728 1.3e-150 yjjH S Calcineurin-like phosphoesterase
COGOJKHO_00729 3e-252 dtpT U amino acid peptide transporter
COGOJKHO_00732 2.2e-229 rodA D Cell cycle protein
COGOJKHO_00733 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
COGOJKHO_00734 7.9e-143 P ATPases associated with a variety of cellular activities
COGOJKHO_00735 2.4e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
COGOJKHO_00736 9.2e-101 L Helix-turn-helix domain
COGOJKHO_00737 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
COGOJKHO_00738 3e-66
COGOJKHO_00739 4.6e-75
COGOJKHO_00740 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
COGOJKHO_00741 3.7e-87
COGOJKHO_00742 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
COGOJKHO_00743 2.9e-36 ynzC S UPF0291 protein
COGOJKHO_00744 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
COGOJKHO_00745 6.4e-119 plsC 2.3.1.51 I Acyltransferase
COGOJKHO_00746 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
COGOJKHO_00747 7e-39 yazA L GIY-YIG catalytic domain protein
COGOJKHO_00748 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COGOJKHO_00749 4.7e-134 S Haloacid dehalogenase-like hydrolase
COGOJKHO_00750 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
COGOJKHO_00751 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
COGOJKHO_00752 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
COGOJKHO_00753 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
COGOJKHO_00754 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
COGOJKHO_00755 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
COGOJKHO_00756 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
COGOJKHO_00757 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
COGOJKHO_00758 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
COGOJKHO_00759 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
COGOJKHO_00760 3.3e-217 nusA K Participates in both transcription termination and antitermination
COGOJKHO_00761 9.5e-49 ylxR K Protein of unknown function (DUF448)
COGOJKHO_00762 3.1e-47 ylxQ J ribosomal protein
COGOJKHO_00763 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
COGOJKHO_00764 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
COGOJKHO_00765 2e-264 ydiN 5.4.99.5 G Major Facilitator
COGOJKHO_00766 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
COGOJKHO_00767 8.5e-93
COGOJKHO_00768 2.5e-223 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
COGOJKHO_00769 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
COGOJKHO_00770 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
COGOJKHO_00771 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
COGOJKHO_00772 1.7e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COGOJKHO_00773 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
COGOJKHO_00774 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
COGOJKHO_00775 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
COGOJKHO_00776 0.0 dnaK O Heat shock 70 kDa protein
COGOJKHO_00777 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
COGOJKHO_00778 4.4e-198 pbpX2 V Beta-lactamase
COGOJKHO_00779 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
COGOJKHO_00780 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COGOJKHO_00781 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
COGOJKHO_00782 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COGOJKHO_00783 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
COGOJKHO_00784 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COGOJKHO_00785 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
COGOJKHO_00788 1.4e-49
COGOJKHO_00789 1.4e-49
COGOJKHO_00790 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
COGOJKHO_00791 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
COGOJKHO_00792 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
COGOJKHO_00793 9.6e-58
COGOJKHO_00794 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
COGOJKHO_00795 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
COGOJKHO_00796 6.5e-116 3.1.3.18 J HAD-hyrolase-like
COGOJKHO_00797 1.6e-160 yniA G Fructosamine kinase
COGOJKHO_00798 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
COGOJKHO_00799 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
COGOJKHO_00800 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
COGOJKHO_00801 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COGOJKHO_00802 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
COGOJKHO_00803 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGOJKHO_00804 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
COGOJKHO_00805 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
COGOJKHO_00806 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
COGOJKHO_00807 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
COGOJKHO_00808 2.6e-71 yqeY S YqeY-like protein
COGOJKHO_00809 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
COGOJKHO_00810 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
COGOJKHO_00811 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
COGOJKHO_00812 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
COGOJKHO_00813 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
COGOJKHO_00814 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
COGOJKHO_00815 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
COGOJKHO_00816 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
COGOJKHO_00817 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
COGOJKHO_00818 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
COGOJKHO_00819 4.8e-165 ytrB V ABC transporter, ATP-binding protein
COGOJKHO_00820 5.9e-202
COGOJKHO_00821 1.5e-197
COGOJKHO_00822 5.2e-128 S ABC-2 family transporter protein
COGOJKHO_00823 5.6e-161 V ABC transporter, ATP-binding protein
COGOJKHO_00824 2.6e-12 yjdF S Protein of unknown function (DUF2992)
COGOJKHO_00825 3.8e-114 S Psort location CytoplasmicMembrane, score
COGOJKHO_00826 2.4e-72 K MarR family
COGOJKHO_00827 6e-82 K Acetyltransferase (GNAT) domain
COGOJKHO_00829 5.2e-159 yvfR V ABC transporter
COGOJKHO_00830 3.1e-136 yvfS V ABC-2 type transporter
COGOJKHO_00831 2.8e-207 desK 2.7.13.3 T Histidine kinase
COGOJKHO_00832 4e-102 desR K helix_turn_helix, Lux Regulon
COGOJKHO_00833 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
COGOJKHO_00834 6.3e-14 S Alpha beta hydrolase
COGOJKHO_00835 1.9e-172 C nadph quinone reductase
COGOJKHO_00836 1.9e-161 K Transcriptional regulator
COGOJKHO_00837 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
COGOJKHO_00838 9.9e-112 GM NmrA-like family
COGOJKHO_00839 8.5e-159 S Alpha beta hydrolase
COGOJKHO_00840 1.3e-128 K Helix-turn-helix domain, rpiR family
COGOJKHO_00841 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
COGOJKHO_00842 3.4e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
COGOJKHO_00843 4e-65 padC Q Phenolic acid decarboxylase
COGOJKHO_00844 6.7e-142 tesE Q hydratase
COGOJKHO_00845 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
COGOJKHO_00846 2.8e-157 degV S DegV family
COGOJKHO_00847 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
COGOJKHO_00848 1.5e-255 pepC 3.4.22.40 E aminopeptidase
COGOJKHO_00850 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COGOJKHO_00851 1.1e-302
COGOJKHO_00853 3e-158 S Bacterial protein of unknown function (DUF916)
COGOJKHO_00854 5.9e-92 S Cell surface protein
COGOJKHO_00855 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
COGOJKHO_00856 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
COGOJKHO_00857 9.1e-109 jag S R3H domain protein
COGOJKHO_00858 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
COGOJKHO_00859 1e-309 E ABC transporter, substratebinding protein
COGOJKHO_00860 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
COGOJKHO_00861 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
COGOJKHO_00862 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
COGOJKHO_00863 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
COGOJKHO_00864 5e-37 yaaA S S4 domain protein YaaA
COGOJKHO_00865 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
COGOJKHO_00866 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COGOJKHO_00867 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
COGOJKHO_00868 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
COGOJKHO_00869 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
COGOJKHO_00870 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
COGOJKHO_00871 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
COGOJKHO_00872 1.4e-67 rplI J Binds to the 23S rRNA
COGOJKHO_00873 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
COGOJKHO_00874 8.8e-226 yttB EGP Major facilitator Superfamily
COGOJKHO_00875 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
COGOJKHO_00876 1.2e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
COGOJKHO_00878 4.2e-276 E ABC transporter, substratebinding protein
COGOJKHO_00879 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
COGOJKHO_00880 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
COGOJKHO_00881 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
COGOJKHO_00882 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
COGOJKHO_00883 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
COGOJKHO_00884 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
COGOJKHO_00885 4.5e-143 S haloacid dehalogenase-like hydrolase
COGOJKHO_00886 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COGOJKHO_00887 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
COGOJKHO_00888 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
COGOJKHO_00889 1.6e-31 cspA K Cold shock protein domain
COGOJKHO_00890 1.7e-37
COGOJKHO_00892 6.2e-131 K response regulator
COGOJKHO_00893 0.0 vicK 2.7.13.3 T Histidine kinase
COGOJKHO_00894 1.2e-244 yycH S YycH protein
COGOJKHO_00895 2.2e-151 yycI S YycH protein
COGOJKHO_00896 8.9e-158 vicX 3.1.26.11 S domain protein
COGOJKHO_00897 6.8e-173 htrA 3.4.21.107 O serine protease
COGOJKHO_00898 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
COGOJKHO_00899 1.5e-95 K Bacterial regulatory proteins, tetR family
COGOJKHO_00900 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
COGOJKHO_00901 7.2e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
COGOJKHO_00902 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
COGOJKHO_00903 4.2e-32 pnb C nitroreductase
COGOJKHO_00904 5.7e-67 pnb C nitroreductase
COGOJKHO_00905 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
COGOJKHO_00906 1.8e-116 S Elongation factor G-binding protein, N-terminal
COGOJKHO_00907 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
COGOJKHO_00908 1.3e-257 P Sodium:sulfate symporter transmembrane region
COGOJKHO_00909 5.7e-158 K LysR family
COGOJKHO_00910 1e-72 C FMN binding
COGOJKHO_00911 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
COGOJKHO_00912 2.3e-164 ptlF S KR domain
COGOJKHO_00913 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
COGOJKHO_00914 1.3e-122 drgA C Nitroreductase family
COGOJKHO_00915 1.3e-290 QT PucR C-terminal helix-turn-helix domain
COGOJKHO_00916 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
COGOJKHO_00917 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COGOJKHO_00918 7.4e-250 yjjP S Putative threonine/serine exporter
COGOJKHO_00919 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
COGOJKHO_00920 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
COGOJKHO_00921 2.9e-81 6.3.3.2 S ASCH
COGOJKHO_00922 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
COGOJKHO_00923 5.5e-172 yobV1 K WYL domain
COGOJKHO_00924 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COGOJKHO_00925 0.0 tetP J elongation factor G
COGOJKHO_00926 8.2e-39 S Protein of unknown function
COGOJKHO_00927 2.1e-61 S Protein of unknown function
COGOJKHO_00928 8e-152 EG EamA-like transporter family
COGOJKHO_00929 3.6e-93 MA20_25245 K FR47-like protein
COGOJKHO_00930 2e-126 hchA S DJ-1/PfpI family
COGOJKHO_00931 5.4e-181 1.1.1.1 C nadph quinone reductase
COGOJKHO_00932 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_00933 2.3e-235 mepA V MATE efflux family protein
COGOJKHO_00934 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
COGOJKHO_00935 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
COGOJKHO_00936 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
COGOJKHO_00937 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
COGOJKHO_00938 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
COGOJKHO_00939 9.3e-109 tdk 2.7.1.21 F thymidine kinase
COGOJKHO_00940 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
COGOJKHO_00941 6.5e-136 cobQ S glutamine amidotransferase
COGOJKHO_00942 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
COGOJKHO_00943 1.2e-191 ampC V Beta-lactamase
COGOJKHO_00944 5.2e-29
COGOJKHO_00945 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
COGOJKHO_00946 1.9e-58
COGOJKHO_00947 2.8e-126
COGOJKHO_00948 0.0 yfiC V ABC transporter
COGOJKHO_00949 2.2e-310 ycfI V ABC transporter, ATP-binding protein
COGOJKHO_00950 3.3e-65 S Protein of unknown function (DUF1093)
COGOJKHO_00951 1.3e-132 yxkH G Polysaccharide deacetylase
COGOJKHO_00952 3.3e-61 V Abortive infection bacteriophage resistance protein
COGOJKHO_00953 2.7e-27 hol S Bacteriophage holin
COGOJKHO_00954 1.6e-192 lys M Glycosyl hydrolases family 25
COGOJKHO_00956 5.9e-21
COGOJKHO_00957 1e-87
COGOJKHO_00960 2.6e-15 S Domain of unknown function (DUF2479)
COGOJKHO_00961 3.3e-96 S Domain of unknown function (DUF2479)
COGOJKHO_00962 1.2e-172 E GDSL-like Lipase/Acylhydrolase family
COGOJKHO_00963 1e-289 M Prophage endopeptidase tail
COGOJKHO_00964 8.1e-134 S phage tail
COGOJKHO_00965 0.0 D NLP P60 protein
COGOJKHO_00967 4.3e-83 S Phage tail assembly chaperone protein, TAC
COGOJKHO_00968 6.7e-96
COGOJKHO_00969 4.1e-61
COGOJKHO_00970 3.6e-94
COGOJKHO_00971 1.7e-50
COGOJKHO_00972 1.5e-56 S Phage gp6-like head-tail connector protein
COGOJKHO_00973 1.5e-194 gpG
COGOJKHO_00974 8.6e-71 S Domain of unknown function (DUF4355)
COGOJKHO_00975 2.9e-168 S Phage Mu protein F like protein
COGOJKHO_00976 7.6e-305 S Phage portal protein, SPP1 Gp6-like
COGOJKHO_00977 8.7e-248 S Phage terminase, large subunit
COGOJKHO_00979 2e-75 ps333 L Terminase small subunit
COGOJKHO_00980 3.5e-11
COGOJKHO_00982 2.2e-17
COGOJKHO_00983 6.6e-31 rplV S ASCH
COGOJKHO_00984 1.3e-79 K acetyltransferase
COGOJKHO_00988 4.1e-14
COGOJKHO_00989 2.4e-13 S YopX protein
COGOJKHO_00991 1.9e-14 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
COGOJKHO_00992 2.2e-50
COGOJKHO_00993 2.5e-161 L DnaD domain protein
COGOJKHO_00994 1.4e-64
COGOJKHO_00995 1.6e-54 S Bacteriophage Mu Gam like protein
COGOJKHO_00997 2.8e-85
COGOJKHO_00998 4.5e-54
COGOJKHO_01000 1.3e-37 K Helix-turn-helix
COGOJKHO_01001 4.5e-61 yvaO K Helix-turn-helix domain
COGOJKHO_01002 3.3e-76 E IrrE N-terminal-like domain
COGOJKHO_01003 8.4e-37
COGOJKHO_01005 4.1e-13 S DNA/RNA non-specific endonuclease
COGOJKHO_01009 7.3e-219 int L Belongs to the 'phage' integrase family
COGOJKHO_01011 8.9e-30
COGOJKHO_01014 3.6e-61
COGOJKHO_01015 1.1e-35 S Phage gp6-like head-tail connector protein
COGOJKHO_01016 7.2e-278 S Caudovirus prohead serine protease
COGOJKHO_01017 1.1e-203 S Phage portal protein
COGOJKHO_01019 0.0 terL S overlaps another CDS with the same product name
COGOJKHO_01020 2.5e-83 terS L Phage terminase, small subunit
COGOJKHO_01021 1.6e-67 L Phage-associated protein
COGOJKHO_01022 4.6e-47 S head-tail joining protein
COGOJKHO_01024 7e-74
COGOJKHO_01025 7.9e-263 S Virulence-associated protein E
COGOJKHO_01026 4.1e-147 L DNA replication protein
COGOJKHO_01027 1.6e-29
COGOJKHO_01031 6.4e-226 sip L Belongs to the 'phage' integrase family
COGOJKHO_01032 2e-38
COGOJKHO_01033 1.4e-43
COGOJKHO_01034 7.3e-83 K MarR family
COGOJKHO_01035 0.0 bztC D nuclear chromosome segregation
COGOJKHO_01036 2.8e-167 M MucBP domain
COGOJKHO_01037 1.5e-14
COGOJKHO_01038 4.7e-16
COGOJKHO_01039 1.5e-14
COGOJKHO_01040 4.2e-18
COGOJKHO_01041 1.6e-16
COGOJKHO_01042 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
COGOJKHO_01043 2e-61 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01044 2e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01045 0.0 macB3 V ABC transporter, ATP-binding protein
COGOJKHO_01046 6.8e-24
COGOJKHO_01047 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
COGOJKHO_01048 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
COGOJKHO_01049 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
COGOJKHO_01050 1.1e-225 patA 2.6.1.1 E Aminotransferase
COGOJKHO_01051 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COGOJKHO_01052 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
COGOJKHO_01053 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
COGOJKHO_01054 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
COGOJKHO_01055 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
COGOJKHO_01056 2.7e-39 ptsH G phosphocarrier protein HPR
COGOJKHO_01057 6.5e-30
COGOJKHO_01058 0.0 clpE O Belongs to the ClpA ClpB family
COGOJKHO_01059 2.2e-73 L Integrase
COGOJKHO_01060 1e-63 K Winged helix DNA-binding domain
COGOJKHO_01061 1.8e-181 oppF P Belongs to the ABC transporter superfamily
COGOJKHO_01062 9.2e-203 oppD P Belongs to the ABC transporter superfamily
COGOJKHO_01063 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
COGOJKHO_01064 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
COGOJKHO_01065 1.3e-309 oppA E ABC transporter, substratebinding protein
COGOJKHO_01066 3.2e-57 ywjH S Protein of unknown function (DUF1634)
COGOJKHO_01067 5.5e-126 yxaA S membrane transporter protein
COGOJKHO_01068 7.1e-161 lysR5 K LysR substrate binding domain
COGOJKHO_01069 2.7e-196 M MucBP domain
COGOJKHO_01070 1.7e-273
COGOJKHO_01071 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
COGOJKHO_01072 2.4e-253 gor 1.8.1.7 C Glutathione reductase
COGOJKHO_01073 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
COGOJKHO_01074 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
COGOJKHO_01075 9.5e-213 gntP EG Gluconate
COGOJKHO_01076 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
COGOJKHO_01077 9.3e-188 yueF S AI-2E family transporter
COGOJKHO_01078 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COGOJKHO_01079 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
COGOJKHO_01080 7.8e-48 K sequence-specific DNA binding
COGOJKHO_01081 2.5e-133 cwlO M NlpC/P60 family
COGOJKHO_01082 4.1e-106 ygaC J Belongs to the UPF0374 family
COGOJKHO_01083 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
COGOJKHO_01084 3e-125
COGOJKHO_01085 6.8e-101 K DNA-templated transcription, initiation
COGOJKHO_01086 1.3e-25
COGOJKHO_01087 7e-30
COGOJKHO_01088 7.3e-33 S Protein of unknown function (DUF2922)
COGOJKHO_01089 3.8e-53
COGOJKHO_01090 2.2e-17 L Helix-turn-helix domain
COGOJKHO_01091 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_01092 1.4e-154 yihY S Belongs to the UPF0761 family
COGOJKHO_01093 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
COGOJKHO_01094 1.2e-219 pbpX1 V Beta-lactamase
COGOJKHO_01095 8.4e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
COGOJKHO_01096 1.4e-106
COGOJKHO_01097 1.3e-73
COGOJKHO_01099 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_01100 2.9e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_01101 2.3e-75 T Universal stress protein family
COGOJKHO_01103 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
COGOJKHO_01104 2.4e-189 mocA S Oxidoreductase
COGOJKHO_01105 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
COGOJKHO_01106 1.1e-62 S Domain of unknown function (DUF4828)
COGOJKHO_01107 2e-143 lys M Glycosyl hydrolases family 25
COGOJKHO_01108 2.3e-151 gntR K rpiR family
COGOJKHO_01109 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_01110 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_01111 0.0 yfgQ P E1-E2 ATPase
COGOJKHO_01112 6e-100 yobS K Bacterial regulatory proteins, tetR family
COGOJKHO_01113 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COGOJKHO_01114 1e-190 yegS 2.7.1.107 G Lipid kinase
COGOJKHO_01115 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COGOJKHO_01116 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
COGOJKHO_01117 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
COGOJKHO_01118 2.6e-198 camS S sex pheromone
COGOJKHO_01119 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COGOJKHO_01120 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
COGOJKHO_01121 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
COGOJKHO_01122 1e-93 S UPF0316 protein
COGOJKHO_01123 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
COGOJKHO_01124 3.4e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
COGOJKHO_01125 7.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
COGOJKHO_01126 4.5e-123 yliE T EAL domain
COGOJKHO_01127 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
COGOJKHO_01128 3.1e-104 K Bacterial regulatory proteins, tetR family
COGOJKHO_01129 1.2e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COGOJKHO_01130 1.5e-52
COGOJKHO_01131 3e-72
COGOJKHO_01132 3e-131 1.5.1.39 C nitroreductase
COGOJKHO_01133 8.8e-154 G Transmembrane secretion effector
COGOJKHO_01134 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COGOJKHO_01135 2.1e-143
COGOJKHO_01137 1.9e-71 spxA 1.20.4.1 P ArsC family
COGOJKHO_01138 1.5e-33
COGOJKHO_01139 2.5e-89 V VanZ like family
COGOJKHO_01140 3.6e-242 EGP Major facilitator Superfamily
COGOJKHO_01141 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COGOJKHO_01142 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
COGOJKHO_01143 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COGOJKHO_01144 2.5e-152 licD M LicD family
COGOJKHO_01145 1.2e-82 K Transcriptional regulator
COGOJKHO_01146 1.5e-19
COGOJKHO_01147 1.2e-225 pbuG S permease
COGOJKHO_01148 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COGOJKHO_01149 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
COGOJKHO_01150 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COGOJKHO_01151 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
COGOJKHO_01152 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COGOJKHO_01153 0.0 oatA I Acyltransferase
COGOJKHO_01154 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
COGOJKHO_01155 1.1e-68 O OsmC-like protein
COGOJKHO_01156 2.6e-46
COGOJKHO_01157 2.5e-88
COGOJKHO_01158 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
COGOJKHO_01159 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
COGOJKHO_01160 1.8e-19
COGOJKHO_01161 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
COGOJKHO_01162 1.3e-81 zur P Belongs to the Fur family
COGOJKHO_01163 7.1e-12 3.2.1.14 GH18
COGOJKHO_01164 4.9e-148
COGOJKHO_01165 1.7e-73 gph 3.1.3.18 S HAD hydrolase, family IA, variant
COGOJKHO_01166 3.2e-184 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
COGOJKHO_01167 9.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COGOJKHO_01168 3.6e-41
COGOJKHO_01170 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_01171 7.8e-149 glnH ET ABC transporter substrate-binding protein
COGOJKHO_01172 1.6e-109 gluC P ABC transporter permease
COGOJKHO_01173 4e-108 glnP P ABC transporter permease
COGOJKHO_01174 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COGOJKHO_01175 1.4e-153 K CAT RNA binding domain
COGOJKHO_01176 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
COGOJKHO_01177 6.1e-140 G YdjC-like protein
COGOJKHO_01178 1.4e-245 steT E amino acid
COGOJKHO_01179 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_01180 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
COGOJKHO_01181 2.8e-70 K MarR family
COGOJKHO_01182 4.9e-210 EGP Major facilitator Superfamily
COGOJKHO_01183 3.8e-85 S membrane transporter protein
COGOJKHO_01184 7.1e-98 K Bacterial regulatory proteins, tetR family
COGOJKHO_01185 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
COGOJKHO_01186 2.9e-78 3.6.1.55 F NUDIX domain
COGOJKHO_01187 1.3e-48 sugE U Multidrug resistance protein
COGOJKHO_01188 1.2e-26
COGOJKHO_01189 5.5e-129 pgm3 G Phosphoglycerate mutase family
COGOJKHO_01190 4.7e-125 pgm3 G Phosphoglycerate mutase family
COGOJKHO_01191 0.0 yjbQ P TrkA C-terminal domain protein
COGOJKHO_01192 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
COGOJKHO_01193 7.2e-110 dedA S SNARE associated Golgi protein
COGOJKHO_01194 0.0 helD 3.6.4.12 L DNA helicase
COGOJKHO_01195 2.5e-164 fabK 1.3.1.9 S Nitronate monooxygenase
COGOJKHO_01196 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
COGOJKHO_01197 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
COGOJKHO_01199 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
COGOJKHO_01201 7.6e-46 L Helix-turn-helix domain
COGOJKHO_01202 6.9e-29 L hmm pf00665
COGOJKHO_01203 8.9e-23 L hmm pf00665
COGOJKHO_01204 4.3e-78
COGOJKHO_01205 6.2e-50
COGOJKHO_01206 1.7e-63 K Helix-turn-helix XRE-family like proteins
COGOJKHO_01211 5.1e-08
COGOJKHO_01216 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
COGOJKHO_01217 8.9e-182 P secondary active sulfate transmembrane transporter activity
COGOJKHO_01218 1.4e-95
COGOJKHO_01219 2e-94 K Acetyltransferase (GNAT) domain
COGOJKHO_01220 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
COGOJKHO_01221 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
COGOJKHO_01223 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
COGOJKHO_01224 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
COGOJKHO_01225 9.2e-256 mmuP E amino acid
COGOJKHO_01226 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
COGOJKHO_01227 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01228 1.6e-121
COGOJKHO_01229 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
COGOJKHO_01230 5.5e-278 bmr3 EGP Major facilitator Superfamily
COGOJKHO_01231 1.7e-18 N Cell shape-determining protein MreB
COGOJKHO_01232 2.1e-139 N Cell shape-determining protein MreB
COGOJKHO_01233 0.0 S Pfam Methyltransferase
COGOJKHO_01234 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01235 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01236 4.2e-29
COGOJKHO_01237 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
COGOJKHO_01238 1.4e-124 3.6.1.27 I Acid phosphatase homologues
COGOJKHO_01239 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
COGOJKHO_01240 3e-301 ytgP S Polysaccharide biosynthesis protein
COGOJKHO_01241 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
COGOJKHO_01242 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
COGOJKHO_01243 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
COGOJKHO_01244 4.1e-84 uspA T Belongs to the universal stress protein A family
COGOJKHO_01245 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
COGOJKHO_01246 5.2e-173 ugpA U Binding-protein-dependent transport system inner membrane component
COGOJKHO_01247 1.1e-150 ugpE G ABC transporter permease
COGOJKHO_01248 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
COGOJKHO_01249 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
COGOJKHO_01250 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
COGOJKHO_01251 3.9e-179 XK27_06930 V domain protein
COGOJKHO_01253 2.6e-124 V Transport permease protein
COGOJKHO_01254 2.3e-156 V ABC transporter
COGOJKHO_01255 4e-176 K LytTr DNA-binding domain
COGOJKHO_01257 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
COGOJKHO_01258 1.6e-64 K helix_turn_helix, mercury resistance
COGOJKHO_01259 3.5e-117 GM NAD(P)H-binding
COGOJKHO_01260 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
COGOJKHO_01261 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
COGOJKHO_01262 1.7e-108
COGOJKHO_01263 2.5e-223 pltK 2.7.13.3 T GHKL domain
COGOJKHO_01264 1.6e-137 pltR K LytTr DNA-binding domain
COGOJKHO_01265 4.5e-55
COGOJKHO_01266 2.5e-59
COGOJKHO_01267 1.9e-113 S CAAX protease self-immunity
COGOJKHO_01268 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_01269 1e-90
COGOJKHO_01270 2.5e-46
COGOJKHO_01271 0.0 uvrA2 L ABC transporter
COGOJKHO_01273 5.9e-52
COGOJKHO_01274 3.5e-10
COGOJKHO_01275 2.1e-180
COGOJKHO_01276 1.9e-89 gtcA S Teichoic acid glycosylation protein
COGOJKHO_01277 3.6e-58 S Protein of unknown function (DUF1516)
COGOJKHO_01278 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
COGOJKHO_01279 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
COGOJKHO_01280 1.2e-307 S Protein conserved in bacteria
COGOJKHO_01281 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
COGOJKHO_01282 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
COGOJKHO_01283 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
COGOJKHO_01284 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
COGOJKHO_01285 0.0 yfbS P Sodium:sulfate symporter transmembrane region
COGOJKHO_01286 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COGOJKHO_01287 3.9e-119 lssY 3.6.1.27 I phosphatase
COGOJKHO_01288 2e-154 I alpha/beta hydrolase fold
COGOJKHO_01289 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
COGOJKHO_01290 3.6e-91 K Transcriptional regulator
COGOJKHO_01291 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
COGOJKHO_01292 1.6e-263 lysP E amino acid
COGOJKHO_01293 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
COGOJKHO_01294 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
COGOJKHO_01295 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COGOJKHO_01303 6.9e-78 ctsR K Belongs to the CtsR family
COGOJKHO_01304 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
COGOJKHO_01305 1.5e-109 K Bacterial regulatory proteins, tetR family
COGOJKHO_01306 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGOJKHO_01307 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGOJKHO_01308 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
COGOJKHO_01309 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
COGOJKHO_01310 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
COGOJKHO_01311 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
COGOJKHO_01312 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
COGOJKHO_01313 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
COGOJKHO_01314 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
COGOJKHO_01315 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
COGOJKHO_01316 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
COGOJKHO_01317 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
COGOJKHO_01318 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
COGOJKHO_01319 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
COGOJKHO_01320 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
COGOJKHO_01321 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
COGOJKHO_01322 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
COGOJKHO_01323 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
COGOJKHO_01324 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
COGOJKHO_01325 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
COGOJKHO_01326 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
COGOJKHO_01327 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
COGOJKHO_01328 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
COGOJKHO_01329 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
COGOJKHO_01330 2.2e-24 rpmD J Ribosomal protein L30
COGOJKHO_01331 6.3e-70 rplO J Binds to the 23S rRNA
COGOJKHO_01332 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
COGOJKHO_01333 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
COGOJKHO_01334 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
COGOJKHO_01335 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
COGOJKHO_01336 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
COGOJKHO_01337 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
COGOJKHO_01338 2.1e-61 rplQ J Ribosomal protein L17
COGOJKHO_01339 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COGOJKHO_01340 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
COGOJKHO_01341 7.2e-86 ynhH S NusG domain II
COGOJKHO_01342 0.0 ndh 1.6.99.3 C NADH dehydrogenase
COGOJKHO_01343 3.5e-142 cad S FMN_bind
COGOJKHO_01344 4.4e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COGOJKHO_01345 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGOJKHO_01346 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGOJKHO_01347 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
COGOJKHO_01348 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
COGOJKHO_01349 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
COGOJKHO_01350 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
COGOJKHO_01351 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
COGOJKHO_01352 2.2e-173 ywhK S Membrane
COGOJKHO_01353 5.5e-30 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COGOJKHO_01354 1.5e-163 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COGOJKHO_01355 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COGOJKHO_01356 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COGOJKHO_01357 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
COGOJKHO_01358 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
COGOJKHO_01360 2.2e-221 P Sodium:sulfate symporter transmembrane region
COGOJKHO_01361 4.1e-53 yitW S Iron-sulfur cluster assembly protein
COGOJKHO_01362 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
COGOJKHO_01363 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
COGOJKHO_01364 7.2e-197 K Helix-turn-helix domain
COGOJKHO_01365 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
COGOJKHO_01366 4.5e-132 mntB 3.6.3.35 P ABC transporter
COGOJKHO_01367 8.2e-141 mtsB U ABC 3 transport family
COGOJKHO_01368 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
COGOJKHO_01369 3.1e-50
COGOJKHO_01370 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COGOJKHO_01371 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
COGOJKHO_01372 2.9e-179 citR K sugar-binding domain protein
COGOJKHO_01373 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
COGOJKHO_01374 1.7e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
COGOJKHO_01375 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
COGOJKHO_01376 9.7e-161 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
COGOJKHO_01377 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
COGOJKHO_01378 4.5e-121 S CAAX protease self-immunity
COGOJKHO_01379 2.5e-114 V CAAX protease self-immunity
COGOJKHO_01380 7.1e-121 yclH V ABC transporter
COGOJKHO_01381 1.8e-185 yclI V MacB-like periplasmic core domain
COGOJKHO_01382 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
COGOJKHO_01383 1.1e-106 tag 3.2.2.20 L glycosylase
COGOJKHO_01384 0.0 ydgH S MMPL family
COGOJKHO_01385 3.1e-104 K transcriptional regulator
COGOJKHO_01386 2.7e-123 2.7.6.5 S RelA SpoT domain protein
COGOJKHO_01387 1.3e-47
COGOJKHO_01388 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
COGOJKHO_01389 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
COGOJKHO_01390 2.1e-41
COGOJKHO_01391 3.2e-55
COGOJKHO_01392 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_01393 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
COGOJKHO_01394 4.1e-49
COGOJKHO_01395 7e-127 K Transcriptional regulatory protein, C terminal
COGOJKHO_01396 9.8e-250 T PhoQ Sensor
COGOJKHO_01397 3.3e-65 K helix_turn_helix, mercury resistance
COGOJKHO_01398 1.1e-251 ydiC1 EGP Major facilitator Superfamily
COGOJKHO_01399 1.4e-40
COGOJKHO_01400 5.9e-38
COGOJKHO_01401 5.1e-116
COGOJKHO_01402 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
COGOJKHO_01403 3.7e-120 K Bacterial regulatory proteins, tetR family
COGOJKHO_01404 1.8e-72 K Transcriptional regulator
COGOJKHO_01405 3.5e-70
COGOJKHO_01406 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
COGOJKHO_01407 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
COGOJKHO_01408 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
COGOJKHO_01409 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
COGOJKHO_01410 1.4e-144
COGOJKHO_01411 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
COGOJKHO_01412 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
COGOJKHO_01413 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
COGOJKHO_01414 3.5e-129 treR K UTRA
COGOJKHO_01415 2.9e-42
COGOJKHO_01416 7.3e-43 S Protein of unknown function (DUF2089)
COGOJKHO_01417 4.3e-141 pnuC H nicotinamide mononucleotide transporter
COGOJKHO_01418 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
COGOJKHO_01419 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
COGOJKHO_01420 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
COGOJKHO_01421 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
COGOJKHO_01422 3.5e-97 yieF S NADPH-dependent FMN reductase
COGOJKHO_01423 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
COGOJKHO_01424 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
COGOJKHO_01425 7.7e-62
COGOJKHO_01426 6.2e-94
COGOJKHO_01427 1.2e-49
COGOJKHO_01428 6.2e-57 trxA1 O Belongs to the thioredoxin family
COGOJKHO_01429 2.1e-73
COGOJKHO_01430 8.1e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
COGOJKHO_01431 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_01432 0.0 mtlR K Mga helix-turn-helix domain
COGOJKHO_01433 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_01434 7.4e-277 pipD E Dipeptidase
COGOJKHO_01435 4.8e-99 K Helix-turn-helix domain
COGOJKHO_01436 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
COGOJKHO_01437 2.2e-173 P Major Facilitator Superfamily
COGOJKHO_01438 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
COGOJKHO_01439 4.7e-31 ygzD K Transcriptional
COGOJKHO_01440 1e-69
COGOJKHO_01441 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
COGOJKHO_01442 1.4e-158 dkgB S reductase
COGOJKHO_01443 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
COGOJKHO_01444 3.1e-101 S ABC transporter permease
COGOJKHO_01445 2e-258 P ABC transporter
COGOJKHO_01446 3.1e-116 P cobalt transport
COGOJKHO_01447 5.6e-19 S ATPases associated with a variety of cellular activities
COGOJKHO_01448 3e-232 pyrP F Permease
COGOJKHO_01449 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
COGOJKHO_01450 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGOJKHO_01451 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
COGOJKHO_01452 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
COGOJKHO_01453 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
COGOJKHO_01454 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
COGOJKHO_01455 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
COGOJKHO_01456 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
COGOJKHO_01457 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COGOJKHO_01458 2.1e-102 J Acetyltransferase (GNAT) domain
COGOJKHO_01459 2.7e-180 mbl D Cell shape determining protein MreB Mrl
COGOJKHO_01460 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
COGOJKHO_01461 1.2e-32 S Protein of unknown function (DUF2969)
COGOJKHO_01462 9.3e-220 rodA D Belongs to the SEDS family
COGOJKHO_01463 3.6e-48 gcsH2 E glycine cleavage
COGOJKHO_01464 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
COGOJKHO_01465 1.4e-111 metI U ABC transporter permease
COGOJKHO_01466 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
COGOJKHO_01467 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
COGOJKHO_01468 1.6e-177 S Protein of unknown function (DUF2785)
COGOJKHO_01469 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
COGOJKHO_01470 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
COGOJKHO_01471 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
COGOJKHO_01472 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
COGOJKHO_01473 6.3e-202 bla2 3.5.2.6 V Beta-lactamase enzyme family
COGOJKHO_01474 6.2e-82 usp6 T universal stress protein
COGOJKHO_01475 1.5e-38
COGOJKHO_01476 8e-238 rarA L recombination factor protein RarA
COGOJKHO_01477 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COGOJKHO_01478 1.9e-43 czrA K Helix-turn-helix domain
COGOJKHO_01479 2.2e-108 S Protein of unknown function (DUF1648)
COGOJKHO_01480 7.3e-80 yueI S Protein of unknown function (DUF1694)
COGOJKHO_01481 5.2e-113 yktB S Belongs to the UPF0637 family
COGOJKHO_01482 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
COGOJKHO_01483 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
COGOJKHO_01484 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
COGOJKHO_01486 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
COGOJKHO_01487 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
COGOJKHO_01488 1.2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
COGOJKHO_01489 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
COGOJKHO_01490 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
COGOJKHO_01491 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COGOJKHO_01492 1.3e-116 radC L DNA repair protein
COGOJKHO_01493 2.8e-161 mreB D cell shape determining protein MreB
COGOJKHO_01494 2.6e-144 mreC M Involved in formation and maintenance of cell shape
COGOJKHO_01495 1.2e-88 mreD M rod shape-determining protein MreD
COGOJKHO_01496 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
COGOJKHO_01497 1.2e-146 minD D Belongs to the ParA family
COGOJKHO_01498 4.6e-109 glnP P ABC transporter permease
COGOJKHO_01499 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_01500 1.5e-155 aatB ET ABC transporter substrate-binding protein
COGOJKHO_01501 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
COGOJKHO_01502 1.9e-231 ymfF S Peptidase M16 inactive domain protein
COGOJKHO_01503 2.9e-251 ymfH S Peptidase M16
COGOJKHO_01504 5.7e-110 ymfM S Helix-turn-helix domain
COGOJKHO_01505 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
COGOJKHO_01506 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
COGOJKHO_01507 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
COGOJKHO_01508 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
COGOJKHO_01509 2.7e-154 ymdB S YmdB-like protein
COGOJKHO_01510 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
COGOJKHO_01511 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
COGOJKHO_01512 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
COGOJKHO_01513 1.6e-140 S Belongs to the UPF0246 family
COGOJKHO_01514 6e-76
COGOJKHO_01515 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
COGOJKHO_01516 7e-141
COGOJKHO_01518 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
COGOJKHO_01519 4.8e-40
COGOJKHO_01520 7.8e-129 cbiO P ABC transporter
COGOJKHO_01521 2.6e-149 P Cobalt transport protein
COGOJKHO_01522 4.8e-182 nikMN P PDGLE domain
COGOJKHO_01523 2.1e-120 K Crp-like helix-turn-helix domain
COGOJKHO_01524 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
COGOJKHO_01525 5.9e-124 larB S AIR carboxylase
COGOJKHO_01526 8.5e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
COGOJKHO_01527 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_01528 6.3e-151 larE S NAD synthase
COGOJKHO_01529 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
COGOJKHO_01530 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
COGOJKHO_01531 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
COGOJKHO_01532 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
COGOJKHO_01533 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
COGOJKHO_01534 4.3e-135 S peptidase C26
COGOJKHO_01535 9.8e-302 L HIRAN domain
COGOJKHO_01536 3.4e-85 F NUDIX domain
COGOJKHO_01537 2.6e-250 yifK E Amino acid permease
COGOJKHO_01538 5.2e-122
COGOJKHO_01539 3.3e-149 ydjP I Alpha/beta hydrolase family
COGOJKHO_01540 0.0 pacL1 P P-type ATPase
COGOJKHO_01541 2.9e-142 2.4.2.3 F Phosphorylase superfamily
COGOJKHO_01542 1.6e-28 KT PspC domain
COGOJKHO_01543 3.6e-111 S NADPH-dependent FMN reductase
COGOJKHO_01544 1.2e-74 papX3 K Transcriptional regulator
COGOJKHO_01545 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
COGOJKHO_01546 5.8e-82 S Protein of unknown function (DUF3021)
COGOJKHO_01547 4.7e-227 mdtG EGP Major facilitator Superfamily
COGOJKHO_01548 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_01549 8.1e-216 yeaN P Transporter, major facilitator family protein
COGOJKHO_01551 3.4e-160 S reductase
COGOJKHO_01552 1.2e-165 1.1.1.65 C Aldo keto reductase
COGOJKHO_01553 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
COGOJKHO_01554 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
COGOJKHO_01555 7.8e-49
COGOJKHO_01556 2.2e-258
COGOJKHO_01557 4e-209 C Oxidoreductase
COGOJKHO_01558 4.9e-151 cbiQ P cobalt transport
COGOJKHO_01559 0.0 ykoD P ABC transporter, ATP-binding protein
COGOJKHO_01560 2.5e-98 S UPF0397 protein
COGOJKHO_01562 1.6e-129 K UbiC transcription regulator-associated domain protein
COGOJKHO_01563 8.3e-54 K Transcriptional regulator PadR-like family
COGOJKHO_01564 3e-134
COGOJKHO_01565 5.8e-149
COGOJKHO_01566 9.1e-89
COGOJKHO_01567 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
COGOJKHO_01568 2e-169 yjjC V ABC transporter
COGOJKHO_01569 4.3e-297 M Exporter of polyketide antibiotics
COGOJKHO_01570 1.1e-116 K Transcriptional regulator
COGOJKHO_01571 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
COGOJKHO_01572 9.5e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
COGOJKHO_01574 1.9e-92 K Bacterial regulatory proteins, tetR family
COGOJKHO_01575 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COGOJKHO_01576 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COGOJKHO_01577 5.5e-101 dhaL 2.7.1.121 S Dak2
COGOJKHO_01578 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
COGOJKHO_01579 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_01580 1e-190 malR K Transcriptional regulator, LacI family
COGOJKHO_01581 2e-180 yvdE K helix_turn _helix lactose operon repressor
COGOJKHO_01582 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
COGOJKHO_01583 2.9e-148 yxeH S hydrolase
COGOJKHO_01584 9e-264 ywfO S HD domain protein
COGOJKHO_01585 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
COGOJKHO_01586 3.8e-78 ywiB S Domain of unknown function (DUF1934)
COGOJKHO_01587 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
COGOJKHO_01588 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
COGOJKHO_01589 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
COGOJKHO_01590 3.1e-229 tdcC E amino acid
COGOJKHO_01591 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
COGOJKHO_01592 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
COGOJKHO_01593 6.4e-131 S YheO-like PAS domain
COGOJKHO_01594 2.5e-26
COGOJKHO_01595 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
COGOJKHO_01596 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
COGOJKHO_01597 7.8e-41 rpmE2 J Ribosomal protein L31
COGOJKHO_01598 3.2e-214 J translation release factor activity
COGOJKHO_01599 9.2e-127 srtA 3.4.22.70 M sortase family
COGOJKHO_01600 1.7e-91 lemA S LemA family
COGOJKHO_01601 4.6e-139 htpX O Belongs to the peptidase M48B family
COGOJKHO_01602 2e-146
COGOJKHO_01603 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
COGOJKHO_01604 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
COGOJKHO_01605 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
COGOJKHO_01606 9.3e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
COGOJKHO_01607 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
COGOJKHO_01608 0.0 kup P Transport of potassium into the cell
COGOJKHO_01609 2.9e-193 P ABC transporter, substratebinding protein
COGOJKHO_01610 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
COGOJKHO_01611 1.9e-133 P ATPases associated with a variety of cellular activities
COGOJKHO_01612 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
COGOJKHO_01613 8.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
COGOJKHO_01614 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
COGOJKHO_01615 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
COGOJKHO_01616 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
COGOJKHO_01617 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
COGOJKHO_01618 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
COGOJKHO_01619 4.1e-84 S QueT transporter
COGOJKHO_01620 6.2e-114 S (CBS) domain
COGOJKHO_01621 4.2e-264 S Putative peptidoglycan binding domain
COGOJKHO_01622 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
COGOJKHO_01623 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
COGOJKHO_01624 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
COGOJKHO_01625 4.3e-289 yabM S Polysaccharide biosynthesis protein
COGOJKHO_01626 2.2e-42 yabO J S4 domain protein
COGOJKHO_01628 1.1e-63 divIC D Septum formation initiator
COGOJKHO_01629 3.1e-74 yabR J RNA binding
COGOJKHO_01630 6.4e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
COGOJKHO_01631 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
COGOJKHO_01632 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
COGOJKHO_01633 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
COGOJKHO_01634 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGOJKHO_01635 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
COGOJKHO_01636 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
COGOJKHO_01637 9.2e-212 norA EGP Major facilitator Superfamily
COGOJKHO_01638 3.6e-117 yfbR S HD containing hydrolase-like enzyme
COGOJKHO_01639 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
COGOJKHO_01640 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
COGOJKHO_01641 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
COGOJKHO_01642 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
COGOJKHO_01643 7.9e-263 argH 4.3.2.1 E argininosuccinate lyase
COGOJKHO_01644 3.5e-86 S Short repeat of unknown function (DUF308)
COGOJKHO_01645 1.1e-161 rapZ S Displays ATPase and GTPase activities
COGOJKHO_01646 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
COGOJKHO_01647 3.7e-168 whiA K May be required for sporulation
COGOJKHO_01648 9.9e-289 oppA E ABC transporter, substratebinding protein
COGOJKHO_01649 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COGOJKHO_01650 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
COGOJKHO_01652 4.2e-245 rpoN K Sigma-54 factor, core binding domain
COGOJKHO_01653 7.3e-189 cggR K Putative sugar-binding domain
COGOJKHO_01654 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
COGOJKHO_01655 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
COGOJKHO_01656 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
COGOJKHO_01657 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
COGOJKHO_01658 2e-131
COGOJKHO_01659 6.6e-295 clcA P chloride
COGOJKHO_01660 3.5e-30 secG U Preprotein translocase
COGOJKHO_01661 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
COGOJKHO_01662 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
COGOJKHO_01663 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
COGOJKHO_01664 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
COGOJKHO_01665 1.5e-256 glnP P ABC transporter
COGOJKHO_01666 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_01667 6.1e-105 yxjI
COGOJKHO_01668 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
COGOJKHO_01669 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
COGOJKHO_01670 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
COGOJKHO_01671 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
COGOJKHO_01672 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
COGOJKHO_01673 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
COGOJKHO_01674 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
COGOJKHO_01675 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
COGOJKHO_01676 6.2e-168 murB 1.3.1.98 M Cell wall formation
COGOJKHO_01677 0.0 yjcE P Sodium proton antiporter
COGOJKHO_01678 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_01679 2.1e-120 S Protein of unknown function (DUF1361)
COGOJKHO_01680 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
COGOJKHO_01681 1.6e-129 ybbR S YbbR-like protein
COGOJKHO_01682 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
COGOJKHO_01683 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
COGOJKHO_01684 2.1e-31
COGOJKHO_01685 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COGOJKHO_01686 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
COGOJKHO_01687 6.1e-76 T Belongs to the universal stress protein A family
COGOJKHO_01688 1.3e-34
COGOJKHO_01689 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
COGOJKHO_01690 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
COGOJKHO_01691 1.9e-104 GM NAD(P)H-binding
COGOJKHO_01692 6.9e-156 K LysR substrate binding domain
COGOJKHO_01693 3.8e-63 S Domain of unknown function (DUF4440)
COGOJKHO_01694 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
COGOJKHO_01695 8.2e-48
COGOJKHO_01696 3.2e-37
COGOJKHO_01697 2.8e-85 yvbK 3.1.3.25 K GNAT family
COGOJKHO_01698 3.8e-84
COGOJKHO_01700 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
COGOJKHO_01701 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
COGOJKHO_01702 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
COGOJKHO_01704 7.5e-121 macB V ABC transporter, ATP-binding protein
COGOJKHO_01705 0.0 ylbB V ABC transporter permease
COGOJKHO_01706 1.4e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
COGOJKHO_01707 2.9e-78 K transcriptional regulator, MerR family
COGOJKHO_01708 3.2e-76 yphH S Cupin domain
COGOJKHO_01709 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
COGOJKHO_01710 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COGOJKHO_01711 1.4e-210 natB CP ABC-2 family transporter protein
COGOJKHO_01712 7.5e-166 natA S ABC transporter, ATP-binding protein
COGOJKHO_01713 1.2e-91 ogt 2.1.1.63 L Methyltransferase
COGOJKHO_01714 1.8e-46 lytE M LysM domain
COGOJKHO_01716 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
COGOJKHO_01717 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
COGOJKHO_01718 4.8e-151 rlrG K Transcriptional regulator
COGOJKHO_01719 9.3e-173 S Conserved hypothetical protein 698
COGOJKHO_01720 1.8e-101 rimL J Acetyltransferase (GNAT) domain
COGOJKHO_01721 2e-75 S Domain of unknown function (DUF4811)
COGOJKHO_01722 4.1e-270 lmrB EGP Major facilitator Superfamily
COGOJKHO_01723 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
COGOJKHO_01724 1.3e-189 ynfM EGP Major facilitator Superfamily
COGOJKHO_01725 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
COGOJKHO_01726 1.2e-155 mleP3 S Membrane transport protein
COGOJKHO_01727 6.4e-117 S Membrane
COGOJKHO_01728 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COGOJKHO_01729 8.1e-99 1.5.1.3 H RibD C-terminal domain
COGOJKHO_01730 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
COGOJKHO_01731 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
COGOJKHO_01732 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
COGOJKHO_01733 5.2e-174 hrtB V ABC transporter permease
COGOJKHO_01734 6.6e-95 S Protein of unknown function (DUF1440)
COGOJKHO_01735 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
COGOJKHO_01736 6.4e-148 KT helix_turn_helix, mercury resistance
COGOJKHO_01737 1.6e-115 S Protein of unknown function (DUF554)
COGOJKHO_01738 1.1e-92 yueI S Protein of unknown function (DUF1694)
COGOJKHO_01739 2e-143 yvpB S Peptidase_C39 like family
COGOJKHO_01740 2.4e-149 M Glycosyl hydrolases family 25
COGOJKHO_01741 3.9e-111
COGOJKHO_01742 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
COGOJKHO_01743 1.8e-84 hmpT S Pfam:DUF3816
COGOJKHO_01744 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
COGOJKHO_01745 0.0 cadA P P-type ATPase
COGOJKHO_01747 1.8e-124 yyaQ S YjbR
COGOJKHO_01748 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
COGOJKHO_01749 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
COGOJKHO_01750 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
COGOJKHO_01751 2.2e-199 frlB M SIS domain
COGOJKHO_01752 3e-26 3.2.2.10 S Belongs to the LOG family
COGOJKHO_01753 3.4e-253 nhaC C Na H antiporter NhaC
COGOJKHO_01754 1.3e-249 cycA E Amino acid permease
COGOJKHO_01755 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_01756 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_01757 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
COGOJKHO_01758 7.7e-160 azoB GM NmrA-like family
COGOJKHO_01759 5.4e-66 K Winged helix DNA-binding domain
COGOJKHO_01760 7e-71 spx4 1.20.4.1 P ArsC family
COGOJKHO_01761 1.7e-66 yeaO S Protein of unknown function, DUF488
COGOJKHO_01762 4e-53
COGOJKHO_01763 4.1e-214 mutY L A G-specific adenine glycosylase
COGOJKHO_01764 1.9e-62
COGOJKHO_01765 4.3e-86
COGOJKHO_01766 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
COGOJKHO_01767 5.9e-55
COGOJKHO_01768 2.1e-14
COGOJKHO_01769 1.1e-115 GM NmrA-like family
COGOJKHO_01770 1.3e-81 elaA S GNAT family
COGOJKHO_01771 5.9e-158 EG EamA-like transporter family
COGOJKHO_01772 1.8e-119 S membrane
COGOJKHO_01773 6.8e-111 S VIT family
COGOJKHO_01774 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
COGOJKHO_01775 0.0 copB 3.6.3.4 P P-type ATPase
COGOJKHO_01776 4.7e-73 copR K Copper transport repressor CopY TcrY
COGOJKHO_01777 7.4e-40
COGOJKHO_01778 7.7e-73 S COG NOG18757 non supervised orthologous group
COGOJKHO_01779 1.5e-248 lmrB EGP Major facilitator Superfamily
COGOJKHO_01780 3.4e-25
COGOJKHO_01781 4.2e-49
COGOJKHO_01782 1.6e-64 ycgX S Protein of unknown function (DUF1398)
COGOJKHO_01783 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
COGOJKHO_01784 5.9e-214 mdtG EGP Major facilitator Superfamily
COGOJKHO_01785 2.6e-180 D Alpha beta
COGOJKHO_01786 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
COGOJKHO_01787 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
COGOJKHO_01788 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
COGOJKHO_01789 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
COGOJKHO_01790 8.4e-152 ywkB S Membrane transport protein
COGOJKHO_01791 5.2e-164 yvgN C Aldo keto reductase
COGOJKHO_01792 9.2e-133 thrE S Putative threonine/serine exporter
COGOJKHO_01793 7.5e-77 S Threonine/Serine exporter, ThrE
COGOJKHO_01794 2.3e-43 S Protein of unknown function (DUF1093)
COGOJKHO_01795 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
COGOJKHO_01796 2.7e-91 ymdB S Macro domain protein
COGOJKHO_01797 1.2e-95 K transcriptional regulator
COGOJKHO_01798 5.5e-50 yvlA
COGOJKHO_01799 6e-161 ypuA S Protein of unknown function (DUF1002)
COGOJKHO_01800 0.0
COGOJKHO_01801 1.7e-121 S Bacterial protein of unknown function (DUF916)
COGOJKHO_01802 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
COGOJKHO_01803 1.2e-286
COGOJKHO_01804 8.2e-205 ftsW D Belongs to the SEDS family
COGOJKHO_01805 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
COGOJKHO_01806 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
COGOJKHO_01807 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
COGOJKHO_01808 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
COGOJKHO_01809 9.6e-197 ylbL T Belongs to the peptidase S16 family
COGOJKHO_01810 6.8e-125 comEA L Competence protein ComEA
COGOJKHO_01811 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
COGOJKHO_01812 0.0 comEC S Competence protein ComEC
COGOJKHO_01813 7e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
COGOJKHO_01814 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
COGOJKHO_01815 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
COGOJKHO_01816 7.2e-103 mdtG EGP Major Facilitator Superfamily
COGOJKHO_01817 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
COGOJKHO_01818 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COGOJKHO_01819 1e-157 S Tetratricopeptide repeat
COGOJKHO_01820 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
COGOJKHO_01821 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
COGOJKHO_01822 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
COGOJKHO_01823 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
COGOJKHO_01824 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
COGOJKHO_01825 9.9e-73 S Iron-sulphur cluster biosynthesis
COGOJKHO_01826 4.3e-22
COGOJKHO_01827 9.2e-270 glnPH2 P ABC transporter permease
COGOJKHO_01828 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_01829 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
COGOJKHO_01830 2.9e-126 epsB M biosynthesis protein
COGOJKHO_01831 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
COGOJKHO_01832 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
COGOJKHO_01833 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
COGOJKHO_01834 7.4e-126 tuaA M Bacterial sugar transferase
COGOJKHO_01835 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
COGOJKHO_01836 2.7e-103 cps4G M Glycosyltransferase Family 4
COGOJKHO_01837 6.5e-38 cps4G M Glycosyltransferase Family 4
COGOJKHO_01838 1.3e-232
COGOJKHO_01839 3e-176 cps4I M Glycosyltransferase like family 2
COGOJKHO_01840 4.5e-261 cps4J S Polysaccharide biosynthesis protein
COGOJKHO_01841 3.8e-251 cpdA S Calcineurin-like phosphoesterase
COGOJKHO_01842 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
COGOJKHO_01843 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
COGOJKHO_01844 1.5e-135 fruR K DeoR C terminal sensor domain
COGOJKHO_01845 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
COGOJKHO_01846 3.2e-46
COGOJKHO_01847 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
COGOJKHO_01848 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
COGOJKHO_01849 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
COGOJKHO_01850 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
COGOJKHO_01851 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
COGOJKHO_01852 1.5e-98 K Helix-turn-helix domain
COGOJKHO_01853 6.1e-211 EGP Major facilitator Superfamily
COGOJKHO_01854 8.5e-57 ybjQ S Belongs to the UPF0145 family
COGOJKHO_01855 1.1e-138 Q Methyltransferase
COGOJKHO_01856 3.6e-31
COGOJKHO_01857 1.1e-161 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
COGOJKHO_01858 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
COGOJKHO_01859 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
COGOJKHO_01860 1.6e-180 galR K Transcriptional regulator
COGOJKHO_01861 8e-76 K Helix-turn-helix XRE-family like proteins
COGOJKHO_01862 2.4e-22 fic D Fic/DOC family
COGOJKHO_01863 1.9e-25 fic D Fic/DOC family
COGOJKHO_01864 2.1e-38 fic D Fic/DOC family
COGOJKHO_01865 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
COGOJKHO_01866 2.5e-231 EGP Major facilitator Superfamily
COGOJKHO_01867 2.1e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
COGOJKHO_01868 2.3e-229 mdtH P Sugar (and other) transporter
COGOJKHO_01869 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
COGOJKHO_01870 0.0 ubiB S ABC1 family
COGOJKHO_01871 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_01872 3.9e-218 3.1.3.1 S associated with various cellular activities
COGOJKHO_01873 1.4e-248 S Putative metallopeptidase domain
COGOJKHO_01874 1.5e-49
COGOJKHO_01875 7.7e-103 K Bacterial regulatory proteins, tetR family
COGOJKHO_01876 4.6e-45
COGOJKHO_01877 2.3e-99 S WxL domain surface cell wall-binding
COGOJKHO_01878 1.5e-118 S WxL domain surface cell wall-binding
COGOJKHO_01879 6.1e-164 S Cell surface protein
COGOJKHO_01880 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
COGOJKHO_01881 1.3e-262 nox C NADH oxidase
COGOJKHO_01882 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
COGOJKHO_01883 0.0 pepO 3.4.24.71 O Peptidase family M13
COGOJKHO_01884 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
COGOJKHO_01885 1.6e-32 copZ P Heavy-metal-associated domain
COGOJKHO_01886 6.6e-96 dps P Belongs to the Dps family
COGOJKHO_01887 1.2e-18
COGOJKHO_01888 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
COGOJKHO_01889 1.5e-55 txlA O Thioredoxin-like domain
COGOJKHO_01890 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_01891 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
COGOJKHO_01892 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
COGOJKHO_01893 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
COGOJKHO_01894 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
COGOJKHO_01895 1.4e-181 yfeX P Peroxidase
COGOJKHO_01896 1.3e-102 K transcriptional regulator
COGOJKHO_01897 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
COGOJKHO_01898 2.6e-65
COGOJKHO_01900 1.6e-61
COGOJKHO_01901 2.5e-53
COGOJKHO_01902 2e-72 mltD CBM50 M PFAM NLP P60 protein
COGOJKHO_01903 4.6e-279 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
COGOJKHO_01904 1.8e-27
COGOJKHO_01905 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
COGOJKHO_01906 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
COGOJKHO_01907 1.3e-87 K Winged helix DNA-binding domain
COGOJKHO_01908 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
COGOJKHO_01909 5.1e-129 S WxL domain surface cell wall-binding
COGOJKHO_01910 2e-56 S Bacterial protein of unknown function (DUF916)
COGOJKHO_01911 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
COGOJKHO_01912 1.2e-103
COGOJKHO_01913 1.1e-172
COGOJKHO_01914 0.0 typA T GTP-binding protein TypA
COGOJKHO_01915 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
COGOJKHO_01916 3.3e-46 yktA S Belongs to the UPF0223 family
COGOJKHO_01917 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
COGOJKHO_01918 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
COGOJKHO_01919 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
COGOJKHO_01920 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
COGOJKHO_01921 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
COGOJKHO_01922 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
COGOJKHO_01923 1.6e-85
COGOJKHO_01924 3.1e-33 ykzG S Belongs to the UPF0356 family
COGOJKHO_01925 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
COGOJKHO_01926 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
COGOJKHO_01927 1.7e-28
COGOJKHO_01928 2.6e-107 mltD CBM50 M NlpC P60 family protein
COGOJKHO_01929 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COGOJKHO_01930 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
COGOJKHO_01931 1.6e-120 S Repeat protein
COGOJKHO_01932 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
COGOJKHO_01933 1.6e-266 N domain, Protein
COGOJKHO_01934 1.9e-192 S Bacterial protein of unknown function (DUF916)
COGOJKHO_01935 2.3e-120 N WxL domain surface cell wall-binding
COGOJKHO_01936 2.6e-115 ktrA P domain protein
COGOJKHO_01937 1.3e-241 ktrB P Potassium uptake protein
COGOJKHO_01938 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
COGOJKHO_01939 4.9e-57 XK27_04120 S Putative amino acid metabolism
COGOJKHO_01940 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
COGOJKHO_01941 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
COGOJKHO_01942 4.6e-28
COGOJKHO_01943 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
COGOJKHO_01944 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
COGOJKHO_01945 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
COGOJKHO_01946 1.2e-86 divIVA D DivIVA domain protein
COGOJKHO_01947 3.4e-146 ylmH S S4 domain protein
COGOJKHO_01948 1.2e-36 yggT S YGGT family
COGOJKHO_01949 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
COGOJKHO_01950 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
COGOJKHO_01951 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
COGOJKHO_01952 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
COGOJKHO_01953 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
COGOJKHO_01954 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
COGOJKHO_01955 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
COGOJKHO_01956 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
COGOJKHO_01957 7.5e-54 ftsL D Cell division protein FtsL
COGOJKHO_01958 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
COGOJKHO_01959 1.9e-77 mraZ K Belongs to the MraZ family
COGOJKHO_01960 1.9e-62 S Protein of unknown function (DUF3397)
COGOJKHO_01961 1.6e-174 corA P CorA-like Mg2+ transporter protein
COGOJKHO_01962 7e-33
COGOJKHO_01964 5.4e-212 livJ E Receptor family ligand binding region
COGOJKHO_01965 2.1e-149 livH U Branched-chain amino acid transport system / permease component
COGOJKHO_01966 5.3e-141 livM E Branched-chain amino acid transport system / permease component
COGOJKHO_01967 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
COGOJKHO_01968 3.3e-124 livF E ABC transporter
COGOJKHO_01969 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
COGOJKHO_01970 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
COGOJKHO_01971 2.3e-91 S WxL domain surface cell wall-binding
COGOJKHO_01972 2.5e-189 S Cell surface protein
COGOJKHO_01973 7.3e-62
COGOJKHO_01974 1e-260
COGOJKHO_01975 1.5e-167 XK27_00670 S ABC transporter
COGOJKHO_01976 5.6e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
COGOJKHO_01977 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
COGOJKHO_01978 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
COGOJKHO_01979 1.3e-119 drgA C Nitroreductase family
COGOJKHO_01980 3e-121 yceE S haloacid dehalogenase-like hydrolase
COGOJKHO_01981 7.1e-159 ccpB 5.1.1.1 K lacI family
COGOJKHO_01982 5e-93 rmaB K Transcriptional regulator, MarR family
COGOJKHO_01983 2.4e-187 lmrA 3.6.3.44 V ABC transporter
COGOJKHO_01984 7.6e-132 lmrA 3.6.3.44 V ABC transporter
COGOJKHO_01985 5.6e-89
COGOJKHO_01986 0.0 ybfG M peptidoglycan-binding domain-containing protein
COGOJKHO_01987 4.2e-161 ypbG 2.7.1.2 GK ROK family
COGOJKHO_01988 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
COGOJKHO_01989 2.5e-112 K Transcriptional regulator C-terminal region
COGOJKHO_01990 1.7e-176 4.1.1.52 S Amidohydrolase
COGOJKHO_01991 1.3e-128 E lipolytic protein G-D-S-L family
COGOJKHO_01992 1.1e-159 yicL EG EamA-like transporter family
COGOJKHO_01993 1.1e-38 sdrF M Collagen binding domain
COGOJKHO_01994 2.5e-269 I acetylesterase activity
COGOJKHO_01995 2.6e-176 S Phosphotransferase system, EIIC
COGOJKHO_01996 1.7e-15 aroD S Alpha/beta hydrolase family
COGOJKHO_01997 8.3e-108 aroD S Alpha/beta hydrolase family
COGOJKHO_01998 3.2e-37
COGOJKHO_02000 2.8e-134 S zinc-ribbon domain
COGOJKHO_02001 1.5e-264 S response to antibiotic
COGOJKHO_02002 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
COGOJKHO_02003 2.4e-243 P Sodium:sulfate symporter transmembrane region
COGOJKHO_02004 1.2e-163 K LysR substrate binding domain
COGOJKHO_02005 2.9e-70
COGOJKHO_02006 4.9e-22
COGOJKHO_02007 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGOJKHO_02008 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COGOJKHO_02009 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
COGOJKHO_02010 2e-80
COGOJKHO_02011 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
COGOJKHO_02012 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COGOJKHO_02013 6.8e-127 yliE T EAL domain
COGOJKHO_02014 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
COGOJKHO_02015 7e-40
COGOJKHO_02017 1.3e-249 EGP Major facilitator Superfamily
COGOJKHO_02018 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
COGOJKHO_02019 4.7e-83 cvpA S Colicin V production protein
COGOJKHO_02020 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
COGOJKHO_02021 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
COGOJKHO_02022 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
COGOJKHO_02023 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
COGOJKHO_02024 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
COGOJKHO_02025 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
COGOJKHO_02026 6.5e-96 tag 3.2.2.20 L glycosylase
COGOJKHO_02027 2.6e-19
COGOJKHO_02028 2.7e-160 czcD P cation diffusion facilitator family transporter
COGOJKHO_02029 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_02030 3e-116 hly S protein, hemolysin III
COGOJKHO_02031 1.1e-44 qacH U Small Multidrug Resistance protein
COGOJKHO_02032 5.8e-59 qacC P Small Multidrug Resistance protein
COGOJKHO_02033 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
COGOJKHO_02034 5.3e-179 K AI-2E family transporter
COGOJKHO_02035 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
COGOJKHO_02036 0.0 kup P Transport of potassium into the cell
COGOJKHO_02038 2.3e-257 yhdG E C-terminus of AA_permease
COGOJKHO_02039 2.1e-82
COGOJKHO_02041 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
COGOJKHO_02042 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
COGOJKHO_02043 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COGOJKHO_02044 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
COGOJKHO_02045 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
COGOJKHO_02046 9.8e-55 S Enterocin A Immunity
COGOJKHO_02047 1.9e-258 gor 1.8.1.7 C Glutathione reductase
COGOJKHO_02048 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
COGOJKHO_02049 4.2e-183 D Alpha beta
COGOJKHO_02050 6.9e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
COGOJKHO_02051 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
COGOJKHO_02052 5e-117 yugP S Putative neutral zinc metallopeptidase
COGOJKHO_02053 4.1e-25
COGOJKHO_02054 7.1e-145 DegV S EDD domain protein, DegV family
COGOJKHO_02055 7.3e-127 lrgB M LrgB-like family
COGOJKHO_02056 5.1e-64 lrgA S LrgA family
COGOJKHO_02057 3.8e-104 J Acetyltransferase (GNAT) domain
COGOJKHO_02058 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
COGOJKHO_02059 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
COGOJKHO_02060 5.4e-36 S Phospholipase_D-nuclease N-terminal
COGOJKHO_02061 7.1e-59 S Enterocin A Immunity
COGOJKHO_02062 1.3e-87 perR P Belongs to the Fur family
COGOJKHO_02063 8.4e-105
COGOJKHO_02064 7.9e-238 S module of peptide synthetase
COGOJKHO_02065 1.1e-77 S NADPH-dependent FMN reductase
COGOJKHO_02066 1.4e-08
COGOJKHO_02067 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
COGOJKHO_02068 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
COGOJKHO_02069 9e-156 1.6.5.2 GM NmrA-like family
COGOJKHO_02070 2e-77 merR K MerR family regulatory protein
COGOJKHO_02071 2.1e-244 dinF V MatE
COGOJKHO_02072 1.9e-31
COGOJKHO_02074 1.5e-77 elaA S Acetyltransferase (GNAT) domain
COGOJKHO_02075 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
COGOJKHO_02076 1.4e-81
COGOJKHO_02077 0.0 yhcA V MacB-like periplasmic core domain
COGOJKHO_02078 1.1e-105
COGOJKHO_02079 0.0 K PRD domain
COGOJKHO_02080 2.4e-62 S Domain of unknown function (DUF3284)
COGOJKHO_02081 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
COGOJKHO_02082 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_02083 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02084 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02085 9.5e-209 EGP Major facilitator Superfamily
COGOJKHO_02086 1.5e-112 M ErfK YbiS YcfS YnhG
COGOJKHO_02087 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
COGOJKHO_02088 2.4e-283 ydfD K Alanine-glyoxylate amino-transferase
COGOJKHO_02089 1.4e-102 argO S LysE type translocator
COGOJKHO_02090 7.1e-214 arcT 2.6.1.1 E Aminotransferase
COGOJKHO_02091 4.4e-77 argR K Regulates arginine biosynthesis genes
COGOJKHO_02092 2.9e-12
COGOJKHO_02093 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
COGOJKHO_02094 1e-54 yheA S Belongs to the UPF0342 family
COGOJKHO_02095 5.7e-233 yhaO L Ser Thr phosphatase family protein
COGOJKHO_02096 0.0 L AAA domain
COGOJKHO_02097 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
COGOJKHO_02098 2.1e-213
COGOJKHO_02099 3.1e-181 3.4.21.102 M Peptidase family S41
COGOJKHO_02100 7.6e-177 K LysR substrate binding domain
COGOJKHO_02101 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
COGOJKHO_02102 0.0 1.3.5.4 C FAD binding domain
COGOJKHO_02103 1.7e-99
COGOJKHO_02104 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
COGOJKHO_02105 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
COGOJKHO_02106 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COGOJKHO_02107 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
COGOJKHO_02108 1.7e-19 S NUDIX domain
COGOJKHO_02109 0.0 S membrane
COGOJKHO_02110 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
COGOJKHO_02111 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
COGOJKHO_02112 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
COGOJKHO_02113 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
COGOJKHO_02114 9.3e-106 GBS0088 S Nucleotidyltransferase
COGOJKHO_02115 5.5e-106
COGOJKHO_02116 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
COGOJKHO_02117 4.7e-74 K Bacterial regulatory proteins, tetR family
COGOJKHO_02118 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COGOJKHO_02119 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
COGOJKHO_02120 0.0 ctpA 3.6.3.54 P P-type ATPase
COGOJKHO_02121 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
COGOJKHO_02122 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
COGOJKHO_02123 1.1e-65 lysM M LysM domain
COGOJKHO_02124 9.6e-267 yjeM E Amino Acid
COGOJKHO_02125 4.3e-144 K Helix-turn-helix XRE-family like proteins
COGOJKHO_02126 7.4e-71
COGOJKHO_02128 7.7e-163 IQ KR domain
COGOJKHO_02129 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
COGOJKHO_02131 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
COGOJKHO_02132 0.0 V ABC transporter
COGOJKHO_02133 8.6e-218 ykiI
COGOJKHO_02134 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
COGOJKHO_02135 1.2e-73 S Psort location Cytoplasmic, score
COGOJKHO_02136 3.3e-219 T diguanylate cyclase
COGOJKHO_02137 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
COGOJKHO_02138 4.2e-92
COGOJKHO_02139 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
COGOJKHO_02140 1.8e-54 nudA S ASCH
COGOJKHO_02141 1.8e-107 S SdpI/YhfL protein family
COGOJKHO_02142 6.7e-87 M Lysin motif
COGOJKHO_02143 2.3e-65 M LysM domain
COGOJKHO_02144 5.1e-75 K helix_turn_helix, mercury resistance
COGOJKHO_02145 5.3e-184 1.1.1.219 GM Male sterility protein
COGOJKHO_02146 9.2e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02147 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02148 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_02149 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COGOJKHO_02150 5.3e-150 dicA K Helix-turn-helix domain
COGOJKHO_02151 3.2e-55
COGOJKHO_02152 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
COGOJKHO_02153 7.4e-64
COGOJKHO_02154 0.0 P Concanavalin A-like lectin/glucanases superfamily
COGOJKHO_02155 0.0 yhcA V ABC transporter, ATP-binding protein
COGOJKHO_02156 1.2e-95 cadD P Cadmium resistance transporter
COGOJKHO_02157 2e-49 K Transcriptional regulator, ArsR family
COGOJKHO_02158 1.9e-116 S SNARE associated Golgi protein
COGOJKHO_02159 1.1e-46
COGOJKHO_02160 6.8e-72 T Belongs to the universal stress protein A family
COGOJKHO_02161 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
COGOJKHO_02162 6.1e-122 K Helix-turn-helix XRE-family like proteins
COGOJKHO_02163 2.8e-82 gtrA S GtrA-like protein
COGOJKHO_02164 6.6e-113 zmp3 O Zinc-dependent metalloprotease
COGOJKHO_02165 3.1e-71
COGOJKHO_02166 0.0 S Bacterial membrane protein YfhO
COGOJKHO_02167 9.6e-89
COGOJKHO_02168 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
COGOJKHO_02169 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
COGOJKHO_02170 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
COGOJKHO_02171 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
COGOJKHO_02172 2.8e-29 yajC U Preprotein translocase
COGOJKHO_02173 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
COGOJKHO_02174 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
COGOJKHO_02175 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
COGOJKHO_02176 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
COGOJKHO_02177 2.4e-43 yrzL S Belongs to the UPF0297 family
COGOJKHO_02178 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
COGOJKHO_02179 1.6e-48 yrzB S Belongs to the UPF0473 family
COGOJKHO_02180 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
COGOJKHO_02181 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
COGOJKHO_02182 3.3e-52 trxA O Belongs to the thioredoxin family
COGOJKHO_02183 7.6e-126 yslB S Protein of unknown function (DUF2507)
COGOJKHO_02184 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
COGOJKHO_02185 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
COGOJKHO_02186 9.5e-97 S Phosphoesterase
COGOJKHO_02187 6.5e-87 ykuL S (CBS) domain
COGOJKHO_02188 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
COGOJKHO_02189 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
COGOJKHO_02190 2.6e-158 ykuT M mechanosensitive ion channel
COGOJKHO_02191 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
COGOJKHO_02192 2.8e-56
COGOJKHO_02193 1.9e-62 K helix_turn_helix, mercury resistance
COGOJKHO_02194 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
COGOJKHO_02195 1.9e-181 ccpA K catabolite control protein A
COGOJKHO_02196 6.8e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
COGOJKHO_02197 1.6e-49 S DsrE/DsrF-like family
COGOJKHO_02198 8.3e-131 yebC K Transcriptional regulatory protein
COGOJKHO_02199 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COGOJKHO_02200 2.1e-174 comGA NU Type II IV secretion system protein
COGOJKHO_02201 1.9e-189 comGB NU type II secretion system
COGOJKHO_02202 5.5e-43 comGC U competence protein ComGC
COGOJKHO_02203 3.2e-83 gspG NU general secretion pathway protein
COGOJKHO_02204 8.6e-20
COGOJKHO_02205 4.5e-88 S Prokaryotic N-terminal methylation motif
COGOJKHO_02207 4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
COGOJKHO_02208 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COGOJKHO_02209 5.3e-251 cycA E Amino acid permease
COGOJKHO_02210 4.4e-117 S Calcineurin-like phosphoesterase
COGOJKHO_02211 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
COGOJKHO_02212 1.5e-80 yutD S Protein of unknown function (DUF1027)
COGOJKHO_02213 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
COGOJKHO_02214 1.8e-116 S Protein of unknown function (DUF1461)
COGOJKHO_02215 1.9e-118 dedA S SNARE-like domain protein
COGOJKHO_02216 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
COGOJKHO_02217 1.6e-75 yugI 5.3.1.9 J general stress protein
COGOJKHO_02218 4.4e-35 yyaN K MerR HTH family regulatory protein
COGOJKHO_02219 1.7e-120 azlC E branched-chain amino acid
COGOJKHO_02220 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
COGOJKHO_02221 0.0 asnB 6.3.5.4 E Asparagine synthase
COGOJKHO_02222 1e-218 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
COGOJKHO_02223 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
COGOJKHO_02224 1e-254 xylP2 G symporter
COGOJKHO_02225 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
COGOJKHO_02226 5.6e-49
COGOJKHO_02227 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
COGOJKHO_02228 2e-91 3.2.2.20 K FR47-like protein
COGOJKHO_02229 3.4e-127 yibF S overlaps another CDS with the same product name
COGOJKHO_02230 1.4e-218 yibE S overlaps another CDS with the same product name
COGOJKHO_02231 3.9e-179
COGOJKHO_02232 5.6e-138 S NADPH-dependent FMN reductase
COGOJKHO_02233 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_02234 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
COGOJKHO_02235 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
COGOJKHO_02236 4.1e-32 L leucine-zipper of insertion element IS481
COGOJKHO_02237 8.5e-41
COGOJKHO_02238 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
COGOJKHO_02239 6.7e-278 pipD E Dipeptidase
COGOJKHO_02240 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
COGOJKHO_02241 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
COGOJKHO_02242 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
COGOJKHO_02243 2.3e-81 rmaD K Transcriptional regulator
COGOJKHO_02245 1.3e-210 1.3.5.4 C FMN_bind
COGOJKHO_02246 1.2e-97 1.3.5.4 C FMN_bind
COGOJKHO_02247 2.8e-171 K Transcriptional regulator
COGOJKHO_02248 5.2e-41 K Helix-turn-helix domain
COGOJKHO_02249 7.2e-47 K Helix-turn-helix domain
COGOJKHO_02250 2.3e-139 K sequence-specific DNA binding
COGOJKHO_02251 6.5e-87 S AAA domain
COGOJKHO_02253 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
COGOJKHO_02254 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
COGOJKHO_02255 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
COGOJKHO_02256 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
COGOJKHO_02257 2.7e-171 L Belongs to the 'phage' integrase family
COGOJKHO_02258 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
COGOJKHO_02259 1.7e-151 hsdM 2.1.1.72 V type I restriction-modification system
COGOJKHO_02260 3.7e-95 hsdM 2.1.1.72 V type I restriction-modification system
COGOJKHO_02261 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COGOJKHO_02262 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
COGOJKHO_02263 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
COGOJKHO_02264 5.6e-39 S Cytochrome B5
COGOJKHO_02265 1.2e-234
COGOJKHO_02266 7e-130 treR K UTRA
COGOJKHO_02267 1.1e-158 I alpha/beta hydrolase fold
COGOJKHO_02268 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
COGOJKHO_02269 2e-233 yxiO S Vacuole effluxer Atg22 like
COGOJKHO_02270 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
COGOJKHO_02271 3.1e-207 EGP Major facilitator Superfamily
COGOJKHO_02272 0.0 uvrA3 L excinuclease ABC
COGOJKHO_02273 0.0 S Predicted membrane protein (DUF2207)
COGOJKHO_02274 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
COGOJKHO_02275 1.2e-307 ybiT S ABC transporter, ATP-binding protein
COGOJKHO_02276 1.1e-223 S CAAX protease self-immunity
COGOJKHO_02277 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
COGOJKHO_02278 6.3e-99 speG J Acetyltransferase (GNAT) domain
COGOJKHO_02279 1.7e-139 endA F DNA RNA non-specific endonuclease
COGOJKHO_02280 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
COGOJKHO_02281 1.5e-95 K Transcriptional regulator (TetR family)
COGOJKHO_02282 1e-197 yhgE V domain protein
COGOJKHO_02287 1.3e-246 EGP Major facilitator Superfamily
COGOJKHO_02288 0.0 mdlA V ABC transporter
COGOJKHO_02289 0.0 mdlB V ABC transporter
COGOJKHO_02291 1.2e-194 C Aldo/keto reductase family
COGOJKHO_02292 7.4e-102 M Protein of unknown function (DUF3737)
COGOJKHO_02293 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
COGOJKHO_02294 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
COGOJKHO_02295 3.1e-63 L Belongs to the 'phage' integrase family
COGOJKHO_02302 4.5e-78 K Peptidase S24-like
COGOJKHO_02303 8.8e-20
COGOJKHO_02306 7.2e-63 S DNA binding
COGOJKHO_02313 6.3e-18
COGOJKHO_02315 2.8e-146 S Protein of unknown function (DUF1351)
COGOJKHO_02316 8.1e-117 S AAA domain
COGOJKHO_02317 1.2e-91 S Protein of unknown function (DUF669)
COGOJKHO_02318 3.9e-130 S Putative HNHc nuclease
COGOJKHO_02319 1.3e-39 S calcium ion binding
COGOJKHO_02320 1.4e-131 pi346 L IstB-like ATP binding protein
COGOJKHO_02324 7e-96 2.1.1.37 L C-5 cytosine-specific DNA methylase
COGOJKHO_02326 1.2e-09 S YopX protein
COGOJKHO_02327 1.4e-55
COGOJKHO_02328 1.4e-15
COGOJKHO_02329 8.2e-65 S Transcriptional regulator, RinA family
COGOJKHO_02331 6.1e-88 L HNH nucleases
COGOJKHO_02333 3.6e-79 L Phage terminase, small subunit
COGOJKHO_02334 0.0 S Phage Terminase
COGOJKHO_02335 2.1e-25 S Protein of unknown function (DUF1056)
COGOJKHO_02336 5.2e-223 S Phage portal protein
COGOJKHO_02337 6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
COGOJKHO_02338 7.5e-201 S Phage capsid family
COGOJKHO_02339 6.2e-49 S Phage gp6-like head-tail connector protein
COGOJKHO_02340 1.7e-57 S Phage head-tail joining protein
COGOJKHO_02341 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
COGOJKHO_02342 3.5e-56 S Protein of unknown function (DUF806)
COGOJKHO_02343 3e-103 S Phage tail tube protein
COGOJKHO_02344 1.8e-57 S Phage tail assembly chaperone proteins, TAC
COGOJKHO_02345 6.6e-24
COGOJKHO_02346 0.0 D NLP P60 protein
COGOJKHO_02347 0.0 S Phage tail protein
COGOJKHO_02348 2.7e-139 S Phage minor structural protein
COGOJKHO_02349 2.3e-88
COGOJKHO_02352 2.9e-71
COGOJKHO_02353 4.7e-20
COGOJKHO_02354 8.5e-151 lys M Glycosyl hydrolases family 25
COGOJKHO_02355 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
COGOJKHO_02356 2.3e-270 G Major Facilitator
COGOJKHO_02357 1.1e-173 K Transcriptional regulator, LacI family
COGOJKHO_02358 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
COGOJKHO_02359 3.8e-159 licT K CAT RNA binding domain
COGOJKHO_02360 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
COGOJKHO_02361 5.5e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02362 3.4e-171 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02363 1.3e-154 licT K CAT RNA binding domain
COGOJKHO_02364 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
COGOJKHO_02365 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02366 1.1e-211 S Bacterial protein of unknown function (DUF871)
COGOJKHO_02367 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
COGOJKHO_02368 4.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
COGOJKHO_02369 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02370 1.2e-134 K UTRA domain
COGOJKHO_02371 3.4e-154 estA S Putative esterase
COGOJKHO_02372 1e-63
COGOJKHO_02373 1.8e-210 ydiN G Major Facilitator Superfamily
COGOJKHO_02374 3.4e-163 K Transcriptional regulator, LysR family
COGOJKHO_02375 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COGOJKHO_02376 2.7e-214 ydiM G Transporter
COGOJKHO_02377 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
COGOJKHO_02378 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
COGOJKHO_02379 0.0 1.3.5.4 C FAD binding domain
COGOJKHO_02380 5.2e-65 S pyridoxamine 5-phosphate
COGOJKHO_02381 3.1e-192 C Aldo keto reductase family protein
COGOJKHO_02382 1.1e-173 galR K Transcriptional regulator
COGOJKHO_02383 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
COGOJKHO_02384 0.0 lacS G Transporter
COGOJKHO_02385 9.2e-131 znuB U ABC 3 transport family
COGOJKHO_02386 9.8e-129 fhuC 3.6.3.35 P ABC transporter
COGOJKHO_02387 1.3e-181 S Prolyl oligopeptidase family
COGOJKHO_02388 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
COGOJKHO_02389 3.2e-37 veg S Biofilm formation stimulator VEG
COGOJKHO_02390 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
COGOJKHO_02391 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
COGOJKHO_02392 1.5e-146 tatD L hydrolase, TatD family
COGOJKHO_02394 1.3e-83 mutR K sequence-specific DNA binding
COGOJKHO_02395 2e-214 bcr1 EGP Major facilitator Superfamily
COGOJKHO_02396 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
COGOJKHO_02397 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
COGOJKHO_02398 2e-160 yunF F Protein of unknown function DUF72
COGOJKHO_02399 2.5e-132 cobB K SIR2 family
COGOJKHO_02400 2.7e-177
COGOJKHO_02401 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
COGOJKHO_02402 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
COGOJKHO_02403 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
COGOJKHO_02404 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COGOJKHO_02405 4.8e-34
COGOJKHO_02406 4.9e-75 S Domain of unknown function (DUF3284)
COGOJKHO_02407 3.9e-24
COGOJKHO_02408 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02409 9e-130 K UbiC transcription regulator-associated domain protein
COGOJKHO_02410 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
COGOJKHO_02411 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
COGOJKHO_02412 0.0 helD 3.6.4.12 L DNA helicase
COGOJKHO_02413 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
COGOJKHO_02414 9.6e-113 S CAAX protease self-immunity
COGOJKHO_02415 1.2e-110 V CAAX protease self-immunity
COGOJKHO_02416 7.4e-118 ypbD S CAAX protease self-immunity
COGOJKHO_02417 1.4e-108 S CAAX protease self-immunity
COGOJKHO_02418 7.5e-242 mesE M Transport protein ComB
COGOJKHO_02419 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
COGOJKHO_02420 5.5e-13
COGOJKHO_02421 2.4e-22 plnF
COGOJKHO_02422 2.2e-129 S CAAX protease self-immunity
COGOJKHO_02423 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
COGOJKHO_02424 4.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COGOJKHO_02425 0.0 rafA 3.2.1.22 G alpha-galactosidase
COGOJKHO_02426 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
COGOJKHO_02427 1.5e-304 scrB 3.2.1.26 GH32 G invertase
COGOJKHO_02428 5.9e-172 scrR K Transcriptional regulator, LacI family
COGOJKHO_02429 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
COGOJKHO_02430 1.4e-164 3.5.1.10 C nadph quinone reductase
COGOJKHO_02431 1.1e-217 nhaC C Na H antiporter NhaC
COGOJKHO_02432 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
COGOJKHO_02433 2.9e-128 mleR K LysR substrate binding domain
COGOJKHO_02434 5e-27 mleR K LysR substrate binding domain
COGOJKHO_02435 0.0 3.6.4.13 M domain protein
COGOJKHO_02437 2.1e-157 hipB K Helix-turn-helix
COGOJKHO_02438 0.0 oppA E ABC transporter, substratebinding protein
COGOJKHO_02439 1.8e-309 oppA E ABC transporter, substratebinding protein
COGOJKHO_02440 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
COGOJKHO_02441 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
COGOJKHO_02442 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
COGOJKHO_02443 3e-113 pgm1 G phosphoglycerate mutase
COGOJKHO_02444 7.2e-178 yghZ C Aldo keto reductase family protein
COGOJKHO_02445 4.9e-34
COGOJKHO_02446 1.3e-60 S Domain of unknown function (DU1801)
COGOJKHO_02447 2.9e-162 FbpA K Domain of unknown function (DUF814)
COGOJKHO_02448 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COGOJKHO_02450 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COGOJKHO_02451 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
COGOJKHO_02452 2.6e-212 S ATPases associated with a variety of cellular activities
COGOJKHO_02453 2.9e-253 S Bacterial membrane protein YfhO
COGOJKHO_02454 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_02455 2.1e-168 K LysR substrate binding domain
COGOJKHO_02456 1.9e-236 EK Aminotransferase, class I
COGOJKHO_02457 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COGOJKHO_02458 8.1e-123 tcyB E ABC transporter
COGOJKHO_02459 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_02460 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
COGOJKHO_02461 5.8e-79 KT response to antibiotic
COGOJKHO_02462 9.8e-52 K Transcriptional regulator
COGOJKHO_02463 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
COGOJKHO_02464 2.1e-126 S Putative adhesin
COGOJKHO_02465 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
COGOJKHO_02466 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
COGOJKHO_02467 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
COGOJKHO_02468 2.6e-205 S DUF218 domain
COGOJKHO_02469 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
COGOJKHO_02470 1.4e-116 ybbL S ABC transporter, ATP-binding protein
COGOJKHO_02471 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
COGOJKHO_02472 9.4e-77
COGOJKHO_02473 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
COGOJKHO_02474 1.1e-147 cof S haloacid dehalogenase-like hydrolase
COGOJKHO_02475 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
COGOJKHO_02476 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
COGOJKHO_02477 3.7e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
COGOJKHO_02478 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_02479 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
COGOJKHO_02480 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COGOJKHO_02481 9.1e-50
COGOJKHO_02482 3e-08
COGOJKHO_02484 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
COGOJKHO_02485 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
COGOJKHO_02486 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
COGOJKHO_02487 2.7e-160 rbsU U ribose uptake protein RbsU
COGOJKHO_02488 3.8e-145 IQ NAD dependent epimerase/dehydratase family
COGOJKHO_02489 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
COGOJKHO_02490 1.1e-86 gutM K Glucitol operon activator protein (GutM)
COGOJKHO_02491 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
COGOJKHO_02492 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
COGOJKHO_02493 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COGOJKHO_02494 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COGOJKHO_02495 8.7e-72 K Transcriptional regulator
COGOJKHO_02496 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
COGOJKHO_02497 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COGOJKHO_02498 5.1e-57 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
COGOJKHO_02500 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
COGOJKHO_02501 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
COGOJKHO_02502 1.8e-12
COGOJKHO_02503 8.7e-160 2.7.13.3 T GHKL domain
COGOJKHO_02504 7.4e-135 K LytTr DNA-binding domain
COGOJKHO_02505 4.9e-78 yneH 1.20.4.1 K ArsC family
COGOJKHO_02506 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
COGOJKHO_02507 9e-13 ytgB S Transglycosylase associated protein
COGOJKHO_02508 3.6e-11
COGOJKHO_02509 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
COGOJKHO_02510 2.4e-114 K UTRA
COGOJKHO_02511 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
COGOJKHO_02512 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02513 4.1e-65
COGOJKHO_02514 6.4e-63 S Protein of unknown function (DUF1093)
COGOJKHO_02515 4.3e-207 S Membrane
COGOJKHO_02516 1.1e-43 S Protein of unknown function (DUF3781)
COGOJKHO_02517 1e-107 ydeA S intracellular protease amidase
COGOJKHO_02518 2.2e-41 K HxlR-like helix-turn-helix
COGOJKHO_02519 3.3e-66
COGOJKHO_02520 1e-64 V ABC transporter
COGOJKHO_02521 2.3e-51 K Helix-turn-helix domain
COGOJKHO_02522 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
COGOJKHO_02523 1.4e-46 K Helix-turn-helix domain
COGOJKHO_02524 1.2e-90 S ABC-2 family transporter protein
COGOJKHO_02525 5.7e-58 S ABC-2 family transporter protein
COGOJKHO_02526 4.6e-91 V ABC transporter, ATP-binding protein
COGOJKHO_02527 8.8e-40
COGOJKHO_02528 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
COGOJKHO_02529 4.9e-172 K AI-2E family transporter
COGOJKHO_02530 1.7e-210 xylR GK ROK family
COGOJKHO_02531 2.3e-81
COGOJKHO_02532 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
COGOJKHO_02533 3.9e-162
COGOJKHO_02534 3.2e-200 KLT Protein tyrosine kinase
COGOJKHO_02535 2.9e-23 S Protein of unknown function (DUF4064)
COGOJKHO_02536 6e-97 S Domain of unknown function (DUF4352)
COGOJKHO_02537 3.9e-75 S Psort location Cytoplasmic, score
COGOJKHO_02538 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
COGOJKHO_02539 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
COGOJKHO_02540 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
COGOJKHO_02541 5.4e-153 nanK GK ROK family
COGOJKHO_02542 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
COGOJKHO_02543 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
COGOJKHO_02544 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
COGOJKHO_02545 1.3e-159 I alpha/beta hydrolase fold
COGOJKHO_02546 1.6e-99 I alpha/beta hydrolase fold
COGOJKHO_02547 2.6e-38 I alpha/beta hydrolase fold
COGOJKHO_02548 3.7e-72 yueI S Protein of unknown function (DUF1694)
COGOJKHO_02549 7.4e-136 K Helix-turn-helix domain, rpiR family
COGOJKHO_02550 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
COGOJKHO_02551 7e-112 K DeoR C terminal sensor domain
COGOJKHO_02552 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COGOJKHO_02553 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
COGOJKHO_02554 1.1e-231 gatC G PTS system sugar-specific permease component
COGOJKHO_02555 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
COGOJKHO_02556 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
COGOJKHO_02557 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COGOJKHO_02558 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
COGOJKHO_02559 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
COGOJKHO_02560 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
COGOJKHO_02561 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
COGOJKHO_02562 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
COGOJKHO_02563 4.3e-144 yxeH S hydrolase
COGOJKHO_02564 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COGOJKHO_02565 4.4e-25 S Immunity protein 74
COGOJKHO_02566 5.1e-52 U domain, Protein
COGOJKHO_02567 1.1e-235 M domain protein
COGOJKHO_02568 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
COGOJKHO_02569 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
COGOJKHO_02570 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
COGOJKHO_02571 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
COGOJKHO_02572 9.9e-180 proV E ABC transporter, ATP-binding protein
COGOJKHO_02573 1.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
COGOJKHO_02574 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
COGOJKHO_02575 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
COGOJKHO_02576 4.5e-174 rihC 3.2.2.1 F Nucleoside
COGOJKHO_02577 2.7e-68 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
COGOJKHO_02578 9.3e-80
COGOJKHO_02579 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
COGOJKHO_02580 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
COGOJKHO_02581 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
COGOJKHO_02582 1.1e-54 ypaA S Protein of unknown function (DUF1304)
COGOJKHO_02583 4.2e-310 mco Q Multicopper oxidase
COGOJKHO_02584 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
COGOJKHO_02585 3.2e-20 zmp1 O Zinc-dependent metalloprotease
COGOJKHO_02586 3.7e-44
COGOJKHO_02587 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
COGOJKHO_02588 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
COGOJKHO_02589 1.3e-66 S Iron-sulphur cluster biosynthesis
COGOJKHO_02590 1.8e-113 S GyrI-like small molecule binding domain
COGOJKHO_02591 2.4e-187 S Cell surface protein
COGOJKHO_02592 2.2e-100 S WxL domain surface cell wall-binding
COGOJKHO_02593 1.1e-62
COGOJKHO_02594 6.9e-210 NU Mycoplasma protein of unknown function, DUF285
COGOJKHO_02595 5.9e-117
COGOJKHO_02596 1e-116 S Haloacid dehalogenase-like hydrolase
COGOJKHO_02597 2e-61 K Transcriptional regulator, HxlR family
COGOJKHO_02598 5.1e-210 ytbD EGP Major facilitator Superfamily
COGOJKHO_02599 1.4e-94 M ErfK YbiS YcfS YnhG
COGOJKHO_02600 0.0 asnB 6.3.5.4 E Asparagine synthase
COGOJKHO_02601 8.2e-134 K LytTr DNA-binding domain
COGOJKHO_02602 4.3e-204 2.7.13.3 T GHKL domain
COGOJKHO_02603 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
COGOJKHO_02604 2e-166 GM NmrA-like family
COGOJKHO_02605 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
COGOJKHO_02606 0.0 M Glycosyl hydrolases family 25
COGOJKHO_02607 1e-47 S Domain of unknown function (DUF1905)
COGOJKHO_02608 8.3e-63 hxlR K HxlR-like helix-turn-helix
COGOJKHO_02609 2.9e-131 ydfG S KR domain
COGOJKHO_02610 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
COGOJKHO_02611 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
COGOJKHO_02612 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
COGOJKHO_02613 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
COGOJKHO_02614 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
COGOJKHO_02615 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
COGOJKHO_02616 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
COGOJKHO_02617 9.4e-297 S Alpha beta
COGOJKHO_02618 1.8e-23
COGOJKHO_02619 3e-99 S ECF transporter, substrate-specific component
COGOJKHO_02620 5.8e-253 yfnA E Amino Acid
COGOJKHO_02621 1.4e-165 mleP S Sodium Bile acid symporter family
COGOJKHO_02622 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
COGOJKHO_02623 1.2e-166 mleR K LysR family
COGOJKHO_02624 4.9e-162 mleR K LysR family transcriptional regulator
COGOJKHO_02625 1e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
COGOJKHO_02626 1.5e-261 frdC 1.3.5.4 C FAD binding domain
COGOJKHO_02627 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
COGOJKHO_02635 5.5e-08
COGOJKHO_02643 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
COGOJKHO_02644 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
COGOJKHO_02645 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
COGOJKHO_02646 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
COGOJKHO_02647 2e-13 coiA 3.6.4.12 S Competence protein
COGOJKHO_02648 2e-180 coiA 3.6.4.12 S Competence protein
COGOJKHO_02649 0.0 pepF E oligoendopeptidase F
COGOJKHO_02650 3.6e-114 yjbH Q Thioredoxin
COGOJKHO_02651 6e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
COGOJKHO_02652 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
COGOJKHO_02653 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
COGOJKHO_02654 1.1e-115 cutC P Participates in the control of copper homeostasis
COGOJKHO_02655 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
COGOJKHO_02656 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
COGOJKHO_02657 4.3e-206 XK27_05220 S AI-2E family transporter
COGOJKHO_02658 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
COGOJKHO_02659 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
COGOJKHO_02661 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
COGOJKHO_02662 2.4e-113 ywnB S NAD(P)H-binding
COGOJKHO_02663 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
COGOJKHO_02664 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
COGOJKHO_02665 4.7e-241 amtB P ammonium transporter
COGOJKHO_02666 1.3e-257 P Major Facilitator Superfamily
COGOJKHO_02667 2.8e-91 K Transcriptional regulator PadR-like family
COGOJKHO_02668 8.4e-44
COGOJKHO_02669 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
COGOJKHO_02670 6e-154 tagG U Transport permease protein
COGOJKHO_02671 3.8e-218
COGOJKHO_02672 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
COGOJKHO_02673 1.8e-61 S CHY zinc finger
COGOJKHO_02674 1.1e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
COGOJKHO_02675 5.7e-95 bioY S BioY family
COGOJKHO_02676 3e-40
COGOJKHO_02677 6.5e-281 pipD E Dipeptidase
COGOJKHO_02678 1.1e-29
COGOJKHO_02679 8.7e-122 qmcA O prohibitin homologues
COGOJKHO_02680 1.5e-239 xylP1 G MFS/sugar transport protein
COGOJKHO_02682 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
COGOJKHO_02683 1.8e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
COGOJKHO_02684 4.9e-190
COGOJKHO_02685 2e-163 ytrB V ABC transporter
COGOJKHO_02686 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
COGOJKHO_02687 8.1e-22
COGOJKHO_02688 8e-91 K acetyltransferase
COGOJKHO_02689 1e-84 K GNAT family
COGOJKHO_02690 1.1e-83 6.3.3.2 S ASCH
COGOJKHO_02691 1.3e-96 puuR K Cupin domain
COGOJKHO_02692 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
COGOJKHO_02693 4.5e-149 potB P ABC transporter permease
COGOJKHO_02694 2.9e-140 potC P ABC transporter permease
COGOJKHO_02695 1.5e-205 potD P ABC transporter
COGOJKHO_02696 4.3e-40
COGOJKHO_02697 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
COGOJKHO_02698 8.4e-75 K Transcriptional regulator
COGOJKHO_02699 4.9e-24 elaA S GNAT family
COGOJKHO_02700 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COGOJKHO_02701 6.8e-57
COGOJKHO_02702 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
COGOJKHO_02703 1.8e-130
COGOJKHO_02704 2.8e-176 sepS16B
COGOJKHO_02705 7.4e-67 gcvH E Glycine cleavage H-protein
COGOJKHO_02706 2.6e-30
COGOJKHO_02707 5.2e-109 S membrane transporter protein
COGOJKHO_02708 2.3e-54 azlD S branched-chain amino acid
COGOJKHO_02709 5.1e-131 azlC E branched-chain amino acid
COGOJKHO_02710 3.2e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
COGOJKHO_02711 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
COGOJKHO_02712 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
COGOJKHO_02713 3.2e-124 K response regulator
COGOJKHO_02714 5.5e-124 yoaK S Protein of unknown function (DUF1275)
COGOJKHO_02715 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
COGOJKHO_02716 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
COGOJKHO_02717 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
COGOJKHO_02718 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
COGOJKHO_02719 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
COGOJKHO_02720 2.4e-156 spo0J K Belongs to the ParB family
COGOJKHO_02721 1.8e-136 soj D Sporulation initiation inhibitor
COGOJKHO_02722 7.9e-149 noc K Belongs to the ParB family
COGOJKHO_02723 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
COGOJKHO_02724 1.2e-225 nupG F Nucleoside
COGOJKHO_02725 2.3e-219 S Bacterial membrane protein YfhO
COGOJKHO_02726 0.0 lacA 3.2.1.23 G -beta-galactosidase
COGOJKHO_02727 0.0 lacS G Transporter
COGOJKHO_02728 1e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
COGOJKHO_02729 1e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
COGOJKHO_02731 0.0 O Belongs to the peptidase S8 family
COGOJKHO_02732 5.3e-19
COGOJKHO_02733 2.6e-79
COGOJKHO_02734 2.8e-21 L Transposase
COGOJKHO_02735 2.5e-175 nsr 3.4.21.102 M Peptidase family S41
COGOJKHO_02736 2.3e-96 K Helix-turn-helix domain
COGOJKHO_02738 1.2e-29
COGOJKHO_02739 6.8e-10 K Helix-turn-helix XRE-family like proteins
COGOJKHO_02740 4.8e-62 S Protein of unknown function (DUF2992)
COGOJKHO_02741 3.2e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
COGOJKHO_02742 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
COGOJKHO_02743 2.8e-105 L Integrase
COGOJKHO_02744 6.1e-45 S Phage derived protein Gp49-like (DUF891)
COGOJKHO_02745 1.7e-36 K sequence-specific DNA binding
COGOJKHO_02746 1.1e-54 S Bacterial mobilisation protein (MobC)
COGOJKHO_02747 1.6e-184 U Relaxase/Mobilisation nuclease domain
COGOJKHO_02748 2.8e-55 repA S Replication initiator protein A
COGOJKHO_02749 2.7e-42
COGOJKHO_02750 0.0 pacL 3.6.3.8 P P-type ATPase
COGOJKHO_02752 6.2e-44 S Psort location CytoplasmicMembrane, score
COGOJKHO_02753 2.1e-20 3.4.21.19 M Belongs to the peptidase S1B family
COGOJKHO_02754 8.3e-17 S Protein of unknown function (DUF1093)
COGOJKHO_02755 6.1e-55 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
COGOJKHO_02756 9e-33
COGOJKHO_02757 3.7e-194 L Psort location Cytoplasmic, score
COGOJKHO_02758 1.2e-129 3.1.21.3 V type I restriction modification DNA specificity domain protein
COGOJKHO_02759 1.3e-301 hsdM 2.1.1.72 V type I restriction-modification system
COGOJKHO_02760 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COGOJKHO_02761 2.7e-10
COGOJKHO_02762 7e-73
COGOJKHO_02763 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
COGOJKHO_02764 4e-281 1.3.5.4 C FAD binding domain
COGOJKHO_02765 1.8e-159 K LysR substrate binding domain
COGOJKHO_02766 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
COGOJKHO_02767 2.5e-289 yjcE P Sodium proton antiporter
COGOJKHO_02768 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
COGOJKHO_02769 8.1e-117 K Bacterial regulatory proteins, tetR family
COGOJKHO_02770 3.1e-51 NU Mycoplasma protein of unknown function, DUF285
COGOJKHO_02771 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
COGOJKHO_02772 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
COGOJKHO_02773 1.4e-161 malD P ABC transporter permease
COGOJKHO_02774 1.6e-149 malA S maltodextrose utilization protein MalA
COGOJKHO_02775 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
COGOJKHO_02776 4e-209 msmK P Belongs to the ABC transporter superfamily
COGOJKHO_02777 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
COGOJKHO_02778 0.0 3.2.1.96 G Glycosyl hydrolase family 85
COGOJKHO_02779 4.6e-25 S Cysteine-rich secretory protein family
COGOJKHO_02780 1.1e-36 S MORN repeat
COGOJKHO_02781 0.0 XK27_09800 I Acyltransferase family
COGOJKHO_02782 7.1e-37 S Transglycosylase associated protein
COGOJKHO_02783 4.4e-84
COGOJKHO_02784 7.2e-23
COGOJKHO_02785 8.7e-72 asp S Asp23 family, cell envelope-related function
COGOJKHO_02786 5.3e-72 asp2 S Asp23 family, cell envelope-related function
COGOJKHO_02787 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
COGOJKHO_02788 1.5e-154 yjdB S Domain of unknown function (DUF4767)
COGOJKHO_02789 3.4e-10 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
COGOJKHO_02790 1.1e-101 G Glycogen debranching enzyme
COGOJKHO_02791 0.0 pepN 3.4.11.2 E aminopeptidase
COGOJKHO_02792 7.3e-86 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
COGOJKHO_02793 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
COGOJKHO_02794 1.4e-77
COGOJKHO_02795 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
COGOJKHO_02796 3.3e-97 FG HIT domain
COGOJKHO_02797 1.7e-173 S Aldo keto reductase
COGOJKHO_02798 1.9e-52 yitW S Pfam:DUF59
COGOJKHO_02799 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
COGOJKHO_02800 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
COGOJKHO_02801 5e-195 blaA6 V Beta-lactamase
COGOJKHO_02802 6.2e-96 V VanZ like family
COGOJKHO_02803 6e-140 K Helix-turn-helix domain
COGOJKHO_02804 2.9e-38 S TfoX C-terminal domain
COGOJKHO_02805 2.3e-227 hpk9 2.7.13.3 T GHKL domain
COGOJKHO_02806 8.4e-263
COGOJKHO_02807 8.4e-75
COGOJKHO_02808 3.6e-183 S Cell surface protein
COGOJKHO_02809 1.7e-101 S WxL domain surface cell wall-binding
COGOJKHO_02810 2.2e-126
COGOJKHO_02811 1.1e-184 S DUF218 domain
COGOJKHO_02812 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
COGOJKHO_02813 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
COGOJKHO_02814 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
COGOJKHO_02815 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
COGOJKHO_02816 2.1e-31
COGOJKHO_02817 1.7e-43 ankB S ankyrin repeats
COGOJKHO_02818 6.5e-91 S ECF-type riboflavin transporter, S component
COGOJKHO_02819 4.2e-47
COGOJKHO_02820 9.8e-214 yceI EGP Major facilitator Superfamily
COGOJKHO_02821 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
COGOJKHO_02822 3.8e-23
COGOJKHO_02824 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_02825 8.2e-173 ykfC 3.4.14.13 M NlpC/P60 family
COGOJKHO_02826 3.3e-80 K AsnC family
COGOJKHO_02827 2e-35
COGOJKHO_02828 3.3e-33
COGOJKHO_02829 5.6e-217 2.7.7.65 T diguanylate cyclase
COGOJKHO_02830 9.7e-155 glcU U sugar transport
COGOJKHO_02831 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
COGOJKHO_02832 2.9e-287 yclK 2.7.13.3 T Histidine kinase
COGOJKHO_02833 1.6e-134 K response regulator
COGOJKHO_02834 3e-243 XK27_08635 S UPF0210 protein
COGOJKHO_02835 2.3e-38 gcvR T Belongs to the UPF0237 family
COGOJKHO_02836 2.6e-169 EG EamA-like transporter family
COGOJKHO_02838 2.8e-88
COGOJKHO_02839 2.9e-176 L Initiator Replication protein
COGOJKHO_02840 2.5e-29
COGOJKHO_02841 2.3e-107 L Integrase
COGOJKHO_02842 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
COGOJKHO_02843 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COGOJKHO_02844 0.0 ybfG M peptidoglycan-binding domain-containing protein
COGOJKHO_02846 1.6e-67 M Cna protein B-type domain
COGOJKHO_02847 3.2e-256 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
COGOJKHO_02848 0.0 traA L MobA MobL family protein
COGOJKHO_02849 3e-25
COGOJKHO_02850 6.2e-32
COGOJKHO_02851 9e-14 Q Methyltransferase
COGOJKHO_02852 2.2e-76 S Threonine/Serine exporter, ThrE
COGOJKHO_02853 1.5e-130 thrE S Putative threonine/serine exporter
COGOJKHO_02854 6e-31 cspC K Cold shock protein
COGOJKHO_02855 2e-120 sirR K iron dependent repressor
COGOJKHO_02856 2.6e-58
COGOJKHO_02857 1.7e-84 merR K MerR HTH family regulatory protein
COGOJKHO_02858 7e-270 lmrB EGP Major facilitator Superfamily
COGOJKHO_02859 1.4e-117 S Domain of unknown function (DUF4811)
COGOJKHO_02860 7.6e-110 XK27_07075 V CAAX protease self-immunity
COGOJKHO_02861 1.1e-56 hxlR K HxlR-like helix-turn-helix
COGOJKHO_02862 1.5e-129 L Helix-turn-helix domain
COGOJKHO_02863 1.7e-159 L hmm pf00665
COGOJKHO_02864 6.7e-232 EGP Major facilitator Superfamily
COGOJKHO_02865 2e-132 S Cysteine-rich secretory protein family
COGOJKHO_02866 2.1e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
COGOJKHO_02867 3.6e-100 dhaL 2.7.1.121 S Dak2
COGOJKHO_02868 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
COGOJKHO_02869 4.7e-97 K Bacterial regulatory proteins, tetR family
COGOJKHO_02870 5.1e-15
COGOJKHO_02871 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
COGOJKHO_02872 3e-80 ydhK M Protein of unknown function (DUF1541)
COGOJKHO_02873 8.3e-38 KT PspC domain protein
COGOJKHO_02874 1.5e-42 S COG NOG38524 non supervised orthologous group
COGOJKHO_02877 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
COGOJKHO_02878 2.8e-239 P Sodium:sulfate symporter transmembrane region
COGOJKHO_02879 2.4e-301 1.3.5.4 C FMN_bind
COGOJKHO_02880 5.4e-132 K LysR family
COGOJKHO_02881 7.9e-60 mleR K LysR substrate binding domain
COGOJKHO_02882 9.2e-28 padC Q Phenolic acid decarboxylase
COGOJKHO_02883 2.2e-99 padR K Virulence activator alpha C-term
COGOJKHO_02884 2.7e-79 T Universal stress protein family
COGOJKHO_02885 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
COGOJKHO_02887 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
COGOJKHO_02888 6.4e-46 M domain protein
COGOJKHO_02889 6e-52 ykoF S YKOF-related Family
COGOJKHO_02890 3.3e-11 glnA 6.3.1.2 E glutamine synthetase
COGOJKHO_02891 1.5e-193 glnA 6.3.1.2 E glutamine synthetase
COGOJKHO_02892 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
COGOJKHO_02893 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
COGOJKHO_02894 2.3e-107 L Integrase
COGOJKHO_02895 4.9e-16
COGOJKHO_02896 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
COGOJKHO_02897 9.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
COGOJKHO_02898 0.0 rafA 3.2.1.22 G alpha-galactosidase
COGOJKHO_02899 1e-96 tnpR1 L Resolvase, N terminal domain
COGOJKHO_02900 6.2e-57 T Belongs to the universal stress protein A family
COGOJKHO_02901 1.5e-249 mntH P H( )-stimulated, divalent metal cation uptake system
COGOJKHO_02902 2.9e-38 sirR K Helix-turn-helix diphteria tox regulatory element
COGOJKHO_02904 2.2e-75 K Copper transport repressor CopY TcrY
COGOJKHO_02905 0.0 copB 3.6.3.4 P P-type ATPase
COGOJKHO_02906 2.8e-117 mdt(A) EGP Major facilitator Superfamily
COGOJKHO_02907 1.2e-198 aspT U Predicted Permease Membrane Region
COGOJKHO_02908 4.5e-238 asdA 4.1.1.12 E Aminotransferase class I and II
COGOJKHO_02909 1.5e-65 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
COGOJKHO_02910 1.3e-117
COGOJKHO_02911 1.5e-65
COGOJKHO_02912 1.9e-54
COGOJKHO_02913 3e-238 EGP Major Facilitator Superfamily
COGOJKHO_02914 0.0 mco Q Multicopper oxidase
COGOJKHO_02915 4.7e-25
COGOJKHO_02917 7.4e-57 L Transposase IS66 family
COGOJKHO_02918 1.5e-194 pbuX F xanthine permease
COGOJKHO_02919 3.7e-24
COGOJKHO_02920 1.9e-56 XK27_01125 L PFAM IS66 Orf2 family protein
COGOJKHO_02921 8e-18
COGOJKHO_02922 5.5e-18
COGOJKHO_02923 1.2e-123 repA S Replication initiator protein A
COGOJKHO_02924 6.7e-246 cycA E Amino acid permease
COGOJKHO_02925 4.2e-144 soj D AAA domain
COGOJKHO_02926 5.2e-34
COGOJKHO_02929 7.6e-55 K helix_turn_helix multiple antibiotic resistance protein
COGOJKHO_02930 0.0 kup P Transport of potassium into the cell
COGOJKHO_02931 4.9e-38 KT Transcriptional regulatory protein, C terminal
COGOJKHO_02932 2.3e-53 XK27_02070 S Nitroreductase
COGOJKHO_02933 0.0 lacS G Transporter
COGOJKHO_02934 1.9e-136 bgaR K helix_turn_helix, arabinose operon control protein
COGOJKHO_02935 4.2e-113 papP P ABC transporter, permease protein
COGOJKHO_02936 4.3e-113 P ABC transporter permease
COGOJKHO_02937 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
COGOJKHO_02938 9.1e-153 cjaA ET ABC transporter substrate-binding protein
COGOJKHO_02940 2.6e-47 S Family of unknown function (DUF5388)
COGOJKHO_02941 1.6e-146 soj D CobQ CobB MinD ParA nucleotide binding domain protein
COGOJKHO_02942 2.8e-220 EGP Major facilitator Superfamily
COGOJKHO_02943 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
COGOJKHO_02944 1.3e-14 3.3.1.1 H adenosylhomocysteinase activity
COGOJKHO_02945 1.7e-18
COGOJKHO_02946 2e-184 L Psort location Cytoplasmic, score
COGOJKHO_02947 8e-68 C lyase activity
COGOJKHO_02948 2.6e-40
COGOJKHO_02949 1.2e-26
COGOJKHO_02951 4.8e-94 K Bacterial regulatory proteins, tetR family
COGOJKHO_02952 1.2e-191 1.1.1.219 GM Male sterility protein
COGOJKHO_02953 1.6e-100 S Protein of unknown function (DUF1211)
COGOJKHO_02954 7.9e-26
COGOJKHO_02955 1.2e-40
COGOJKHO_02956 5.7e-86
COGOJKHO_02957 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
COGOJKHO_02958 2.9e-125 S Phage Mu protein F like protein
COGOJKHO_02959 1.2e-12 ytgB S Transglycosylase associated protein
COGOJKHO_02961 1.6e-39 L Transposase
COGOJKHO_02962 8.8e-95 L 4.5 Transposon and IS
COGOJKHO_02964 1.5e-15 S Alpha/beta hydrolase of unknown function (DUF915)
COGOJKHO_02965 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
COGOJKHO_02966 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
COGOJKHO_02967 1.2e-23 S Family of unknown function (DUF5388)
COGOJKHO_02968 2.7e-10
COGOJKHO_02969 2.1e-11
COGOJKHO_02970 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
COGOJKHO_02971 4.2e-150 S Uncharacterised protein, DegV family COG1307
COGOJKHO_02972 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
COGOJKHO_02973 3.7e-31 tnp2PF3 L manually curated
COGOJKHO_02974 7e-57
COGOJKHO_02975 6e-31 cspA K Cold shock protein
COGOJKHO_02976 3.8e-40
COGOJKHO_02977 5.2e-25
COGOJKHO_02978 2.6e-40
COGOJKHO_02979 4e-151 glcU U sugar transport
COGOJKHO_02980 2.7e-31 L Transposase
COGOJKHO_02981 4.4e-127 terC P integral membrane protein, YkoY family
COGOJKHO_02983 3.1e-36 L Resolvase, N terminal domain
COGOJKHO_02984 1.2e-163 L PFAM Integrase catalytic region
COGOJKHO_02985 4.2e-70 S Pyrimidine dimer DNA glycosylase
COGOJKHO_02986 2.6e-126 tnp L DDE domain
COGOJKHO_02987 4.8e-58
COGOJKHO_02988 1.3e-23 hol S Bacteriophage holin
COGOJKHO_02989 3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
COGOJKHO_02990 5.4e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
COGOJKHO_02992 2.9e-13
COGOJKHO_02994 1.7e-88 L Helix-turn-helix domain
COGOJKHO_02995 1.7e-90 L Transposase and inactivated derivatives, IS30 family
COGOJKHO_02996 4.6e-82 tnp2PF3 L Transposase DDE domain
COGOJKHO_02997 1.7e-81 tnp L DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)