ORF_ID e_value Gene_name EC_number CAZy COGs Description
IIPKEOGD_00001 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IIPKEOGD_00002 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IIPKEOGD_00003 1.6e-129 ybbR S YbbR-like protein
IIPKEOGD_00004 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IIPKEOGD_00005 2.1e-120 S Protein of unknown function (DUF1361)
IIPKEOGD_00006 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_00007 0.0 yjcE P Sodium proton antiporter
IIPKEOGD_00008 6.2e-168 murB 1.3.1.98 M Cell wall formation
IIPKEOGD_00009 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
IIPKEOGD_00010 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
IIPKEOGD_00011 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
IIPKEOGD_00012 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
IIPKEOGD_00013 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IIPKEOGD_00014 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IIPKEOGD_00015 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IIPKEOGD_00016 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
IIPKEOGD_00017 6.1e-105 yxjI
IIPKEOGD_00018 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_00019 1.5e-256 glnP P ABC transporter
IIPKEOGD_00020 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
IIPKEOGD_00021 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IIPKEOGD_00022 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IIPKEOGD_00023 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
IIPKEOGD_00024 3.5e-30 secG U Preprotein translocase
IIPKEOGD_00025 6.6e-295 clcA P chloride
IIPKEOGD_00026 2e-131
IIPKEOGD_00027 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIPKEOGD_00028 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IIPKEOGD_00029 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IIPKEOGD_00030 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IIPKEOGD_00031 7.3e-189 cggR K Putative sugar-binding domain
IIPKEOGD_00032 4.2e-245 rpoN K Sigma-54 factor, core binding domain
IIPKEOGD_00034 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IIPKEOGD_00035 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPKEOGD_00036 9.9e-289 oppA E ABC transporter, substratebinding protein
IIPKEOGD_00037 3.7e-168 whiA K May be required for sporulation
IIPKEOGD_00038 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IIPKEOGD_00039 1.1e-161 rapZ S Displays ATPase and GTPase activities
IIPKEOGD_00040 3.5e-86 S Short repeat of unknown function (DUF308)
IIPKEOGD_00041 7.9e-263 argH 4.3.2.1 E argininosuccinate lyase
IIPKEOGD_00042 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
IIPKEOGD_00043 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IIPKEOGD_00044 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IIPKEOGD_00045 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IIPKEOGD_00046 3.6e-117 yfbR S HD containing hydrolase-like enzyme
IIPKEOGD_00047 9.2e-212 norA EGP Major facilitator Superfamily
IIPKEOGD_00048 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
IIPKEOGD_00049 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IIPKEOGD_00050 3.3e-132 yliE T Putative diguanylate phosphodiesterase
IIPKEOGD_00051 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IIPKEOGD_00052 1.1e-61 S Protein of unknown function (DUF3290)
IIPKEOGD_00053 2e-109 yviA S Protein of unknown function (DUF421)
IIPKEOGD_00054 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IIPKEOGD_00055 3.9e-270 nox C NADH oxidase
IIPKEOGD_00056 1.9e-124 yliE T Putative diguanylate phosphodiesterase
IIPKEOGD_00057 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IIPKEOGD_00058 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IIPKEOGD_00059 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IIPKEOGD_00060 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IIPKEOGD_00061 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
IIPKEOGD_00062 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
IIPKEOGD_00063 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
IIPKEOGD_00064 3.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIPKEOGD_00065 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IIPKEOGD_00066 1.5e-155 pstA P Phosphate transport system permease protein PstA
IIPKEOGD_00067 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
IIPKEOGD_00068 2.1e-149 pstS P Phosphate
IIPKEOGD_00069 3.5e-250 phoR 2.7.13.3 T Histidine kinase
IIPKEOGD_00070 1.5e-132 K response regulator
IIPKEOGD_00071 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
IIPKEOGD_00072 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IIPKEOGD_00073 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IIPKEOGD_00074 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IIPKEOGD_00075 7.5e-126 comFC S Competence protein
IIPKEOGD_00076 9.6e-258 comFA L Helicase C-terminal domain protein
IIPKEOGD_00077 1.7e-114 yvyE 3.4.13.9 S YigZ family
IIPKEOGD_00078 4.3e-145 pstS P Phosphate
IIPKEOGD_00079 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
IIPKEOGD_00080 0.0 ydaO E amino acid
IIPKEOGD_00081 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IIPKEOGD_00082 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IIPKEOGD_00083 6.1e-109 ydiL S CAAX protease self-immunity
IIPKEOGD_00084 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IIPKEOGD_00085 3.3e-307 uup S ABC transporter, ATP-binding protein
IIPKEOGD_00086 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IIPKEOGD_00087 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
IIPKEOGD_00088 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IIPKEOGD_00089 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IIPKEOGD_00090 5.1e-190 phnD P Phosphonate ABC transporter
IIPKEOGD_00091 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IIPKEOGD_00092 2.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
IIPKEOGD_00093 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
IIPKEOGD_00094 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
IIPKEOGD_00095 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
IIPKEOGD_00096 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIPKEOGD_00097 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
IIPKEOGD_00098 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IIPKEOGD_00099 1e-57 yabA L Involved in initiation control of chromosome replication
IIPKEOGD_00100 3.3e-186 holB 2.7.7.7 L DNA polymerase III
IIPKEOGD_00101 2.4e-53 yaaQ S Cyclic-di-AMP receptor
IIPKEOGD_00102 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IIPKEOGD_00103 2.2e-38 yaaL S Protein of unknown function (DUF2508)
IIPKEOGD_00104 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IIPKEOGD_00105 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IIPKEOGD_00106 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIPKEOGD_00107 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IIPKEOGD_00108 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
IIPKEOGD_00109 6.5e-37 nrdH O Glutaredoxin
IIPKEOGD_00110 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIPKEOGD_00111 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IIPKEOGD_00112 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
IIPKEOGD_00113 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIPKEOGD_00114 1.2e-38 L nuclease
IIPKEOGD_00115 9.3e-178 F DNA/RNA non-specific endonuclease
IIPKEOGD_00116 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IIPKEOGD_00117 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IIPKEOGD_00118 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IIPKEOGD_00119 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IIPKEOGD_00120 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_00121 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
IIPKEOGD_00122 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IIPKEOGD_00123 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIPKEOGD_00124 2.4e-101 sigH K Sigma-70 region 2
IIPKEOGD_00125 7.7e-97 yacP S YacP-like NYN domain
IIPKEOGD_00126 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIPKEOGD_00127 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IIPKEOGD_00128 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIPKEOGD_00129 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IIPKEOGD_00130 3.7e-205 yacL S domain protein
IIPKEOGD_00131 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IIPKEOGD_00132 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IIPKEOGD_00133 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
IIPKEOGD_00134 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IIPKEOGD_00135 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
IIPKEOGD_00136 5.2e-113 zmp2 O Zinc-dependent metalloprotease
IIPKEOGD_00137 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIPKEOGD_00138 8.3e-177 EG EamA-like transporter family
IIPKEOGD_00139 5.6e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
IIPKEOGD_00140 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IIPKEOGD_00141 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
IIPKEOGD_00142 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIPKEOGD_00143 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
IIPKEOGD_00144 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
IIPKEOGD_00145 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIPKEOGD_00146 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
IIPKEOGD_00147 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
IIPKEOGD_00148 0.0 levR K Sigma-54 interaction domain
IIPKEOGD_00149 4.7e-64 S Domain of unknown function (DUF956)
IIPKEOGD_00150 4.4e-169 manN G system, mannose fructose sorbose family IID component
IIPKEOGD_00151 3.4e-133 manY G PTS system
IIPKEOGD_00152 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IIPKEOGD_00153 7.4e-152 G Peptidase_C39 like family
IIPKEOGD_00155 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IIPKEOGD_00156 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IIPKEOGD_00157 3.7e-81 ydcK S Belongs to the SprT family
IIPKEOGD_00158 0.0 yhgF K Tex-like protein N-terminal domain protein
IIPKEOGD_00159 3.4e-71
IIPKEOGD_00160 0.0 pacL 3.6.3.8 P P-type ATPase
IIPKEOGD_00161 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IIPKEOGD_00162 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIPKEOGD_00163 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IIPKEOGD_00164 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
IIPKEOGD_00165 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IIPKEOGD_00166 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IIPKEOGD_00167 1.6e-151 pnuC H nicotinamide mononucleotide transporter
IIPKEOGD_00168 4.7e-194 ybiR P Citrate transporter
IIPKEOGD_00169 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IIPKEOGD_00170 2.5e-53 S Cupin domain
IIPKEOGD_00171 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
IIPKEOGD_00175 1.3e-150 yjjH S Calcineurin-like phosphoesterase
IIPKEOGD_00176 3e-252 dtpT U amino acid peptide transporter
IIPKEOGD_00178 7.5e-49 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_00179 1.2e-14 K Bacterial regulatory proteins, tetR family
IIPKEOGD_00180 4.7e-214 S membrane
IIPKEOGD_00181 9.2e-82 K Bacterial regulatory proteins, tetR family
IIPKEOGD_00182 0.0 CP_1020 S Zinc finger, swim domain protein
IIPKEOGD_00183 2e-112 GM epimerase
IIPKEOGD_00184 4.1e-68 S Protein of unknown function (DUF1722)
IIPKEOGD_00185 9.1e-71 yneH 1.20.4.1 P ArsC family
IIPKEOGD_00186 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
IIPKEOGD_00187 8e-137 K DeoR C terminal sensor domain
IIPKEOGD_00188 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IIPKEOGD_00189 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IIPKEOGD_00190 4.3e-77 K Transcriptional regulator
IIPKEOGD_00191 2.2e-241 EGP Major facilitator Superfamily
IIPKEOGD_00192 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IIPKEOGD_00193 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
IIPKEOGD_00194 2.2e-179 C Zinc-binding dehydrogenase
IIPKEOGD_00195 1.5e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
IIPKEOGD_00196 1.7e-207
IIPKEOGD_00197 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_00198 7.8e-61 P Rhodanese Homology Domain
IIPKEOGD_00199 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IIPKEOGD_00200 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_00201 3.2e-167 drrA V ABC transporter
IIPKEOGD_00202 2e-119 drrB U ABC-2 type transporter
IIPKEOGD_00203 6.9e-223 M O-Antigen ligase
IIPKEOGD_00204 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
IIPKEOGD_00205 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IIPKEOGD_00206 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IIPKEOGD_00207 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIPKEOGD_00209 5.6e-29 S Protein of unknown function (DUF2929)
IIPKEOGD_00210 0.0 dnaE 2.7.7.7 L DNA polymerase
IIPKEOGD_00211 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IIPKEOGD_00212 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IIPKEOGD_00213 1.5e-74 yeaL S Protein of unknown function (DUF441)
IIPKEOGD_00214 1.1e-169 cvfB S S1 domain
IIPKEOGD_00215 1.1e-164 xerD D recombinase XerD
IIPKEOGD_00216 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IIPKEOGD_00217 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IIPKEOGD_00218 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IIPKEOGD_00219 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIPKEOGD_00220 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IIPKEOGD_00221 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
IIPKEOGD_00222 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
IIPKEOGD_00223 2e-19 M Lysin motif
IIPKEOGD_00224 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IIPKEOGD_00225 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
IIPKEOGD_00226 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IIPKEOGD_00227 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IIPKEOGD_00228 2.1e-206 S Tetratricopeptide repeat protein
IIPKEOGD_00229 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
IIPKEOGD_00230 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IIPKEOGD_00231 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IIPKEOGD_00232 9.6e-85
IIPKEOGD_00233 0.0 yfmR S ABC transporter, ATP-binding protein
IIPKEOGD_00234 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IIPKEOGD_00235 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IIPKEOGD_00236 5.1e-148 DegV S EDD domain protein, DegV family
IIPKEOGD_00237 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
IIPKEOGD_00238 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
IIPKEOGD_00239 3.4e-35 yozE S Belongs to the UPF0346 family
IIPKEOGD_00240 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
IIPKEOGD_00241 7.3e-251 emrY EGP Major facilitator Superfamily
IIPKEOGD_00242 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
IIPKEOGD_00243 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IIPKEOGD_00244 2.3e-173 L restriction endonuclease
IIPKEOGD_00245 3.1e-170 cpsY K Transcriptional regulator, LysR family
IIPKEOGD_00246 6.8e-228 XK27_05470 E Methionine synthase
IIPKEOGD_00248 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IIPKEOGD_00249 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIPKEOGD_00250 9.5e-158 dprA LU DNA protecting protein DprA
IIPKEOGD_00251 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IIPKEOGD_00252 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IIPKEOGD_00253 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
IIPKEOGD_00254 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IIPKEOGD_00255 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IIPKEOGD_00256 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
IIPKEOGD_00257 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IIPKEOGD_00258 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIPKEOGD_00259 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IIPKEOGD_00260 5.9e-177 K Transcriptional regulator
IIPKEOGD_00261 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
IIPKEOGD_00262 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IIPKEOGD_00263 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIPKEOGD_00264 4.2e-32 S YozE SAM-like fold
IIPKEOGD_00265 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
IIPKEOGD_00266 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIPKEOGD_00267 6.3e-246 M Glycosyl transferase family group 2
IIPKEOGD_00268 1.8e-66
IIPKEOGD_00269 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
IIPKEOGD_00270 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_00271 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IIPKEOGD_00272 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPKEOGD_00273 9.9e-216 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPKEOGD_00274 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
IIPKEOGD_00275 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
IIPKEOGD_00276 5.1e-227
IIPKEOGD_00277 4.6e-275 lldP C L-lactate permease
IIPKEOGD_00278 4.1e-59
IIPKEOGD_00279 3.5e-123
IIPKEOGD_00280 3.2e-245 cycA E Amino acid permease
IIPKEOGD_00281 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
IIPKEOGD_00282 4.6e-129 yejC S Protein of unknown function (DUF1003)
IIPKEOGD_00283 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
IIPKEOGD_00284 4.6e-12
IIPKEOGD_00285 1.6e-211 pmrB EGP Major facilitator Superfamily
IIPKEOGD_00286 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
IIPKEOGD_00287 1.4e-49
IIPKEOGD_00288 1.6e-09
IIPKEOGD_00289 2.9e-131 S Protein of unknown function (DUF975)
IIPKEOGD_00290 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
IIPKEOGD_00291 2.1e-160 degV S EDD domain protein, DegV family
IIPKEOGD_00292 1.9e-66 K Transcriptional regulator
IIPKEOGD_00293 0.0 FbpA K Fibronectin-binding protein
IIPKEOGD_00294 9.3e-133 S ABC-2 family transporter protein
IIPKEOGD_00295 5.4e-164 V ABC transporter, ATP-binding protein
IIPKEOGD_00296 3e-92 3.6.1.55 F NUDIX domain
IIPKEOGD_00297 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
IIPKEOGD_00298 1.2e-69 S LuxR family transcriptional regulator
IIPKEOGD_00299 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
IIPKEOGD_00302 3.1e-71 frataxin S Domain of unknown function (DU1801)
IIPKEOGD_00303 5.5e-112 pgm5 G Phosphoglycerate mutase family
IIPKEOGD_00304 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IIPKEOGD_00305 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
IIPKEOGD_00306 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIPKEOGD_00307 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIPKEOGD_00308 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IIPKEOGD_00309 1.1e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IIPKEOGD_00310 2.2e-61 esbA S Family of unknown function (DUF5322)
IIPKEOGD_00311 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
IIPKEOGD_00312 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
IIPKEOGD_00313 5.9e-146 S hydrolase activity, acting on ester bonds
IIPKEOGD_00314 2.3e-193
IIPKEOGD_00315 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
IIPKEOGD_00316 1.3e-123
IIPKEOGD_00317 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
IIPKEOGD_00318 2.6e-239 M hydrolase, family 25
IIPKEOGD_00319 6.8e-53
IIPKEOGD_00320 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IIPKEOGD_00321 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IIPKEOGD_00322 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IIPKEOGD_00323 2.6e-39 ylqC S Belongs to the UPF0109 family
IIPKEOGD_00324 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IIPKEOGD_00325 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IIPKEOGD_00326 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IIPKEOGD_00327 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IIPKEOGD_00328 0.0 smc D Required for chromosome condensation and partitioning
IIPKEOGD_00329 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IIPKEOGD_00330 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIPKEOGD_00331 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IIPKEOGD_00332 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IIPKEOGD_00333 0.0 yloV S DAK2 domain fusion protein YloV
IIPKEOGD_00334 1.8e-57 asp S Asp23 family, cell envelope-related function
IIPKEOGD_00335 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IIPKEOGD_00336 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
IIPKEOGD_00337 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IIPKEOGD_00338 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIPKEOGD_00339 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IIPKEOGD_00340 1.7e-134 stp 3.1.3.16 T phosphatase
IIPKEOGD_00341 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IIPKEOGD_00342 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IIPKEOGD_00343 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IIPKEOGD_00344 5.7e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IIPKEOGD_00345 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IIPKEOGD_00346 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
IIPKEOGD_00347 4.5e-55
IIPKEOGD_00348 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
IIPKEOGD_00349 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIPKEOGD_00350 1.2e-104 opuCB E ABC transporter permease
IIPKEOGD_00351 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
IIPKEOGD_00352 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
IIPKEOGD_00353 2.2e-76 argR K Regulates arginine biosynthesis genes
IIPKEOGD_00354 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IIPKEOGD_00355 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIPKEOGD_00356 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIPKEOGD_00357 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IIPKEOGD_00358 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IIPKEOGD_00359 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IIPKEOGD_00360 3.5e-74 yqhY S Asp23 family, cell envelope-related function
IIPKEOGD_00361 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IIPKEOGD_00362 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IIPKEOGD_00363 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IIPKEOGD_00364 3.2e-53 ysxB J Cysteine protease Prp
IIPKEOGD_00365 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IIPKEOGD_00366 1.8e-89 K Transcriptional regulator
IIPKEOGD_00367 5.4e-19
IIPKEOGD_00370 1.7e-30
IIPKEOGD_00371 5.3e-56
IIPKEOGD_00372 2.4e-98 dut S Protein conserved in bacteria
IIPKEOGD_00373 4e-181
IIPKEOGD_00374 2e-161
IIPKEOGD_00375 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
IIPKEOGD_00376 4.6e-64 glnR K Transcriptional regulator
IIPKEOGD_00377 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IIPKEOGD_00378 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
IIPKEOGD_00379 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
IIPKEOGD_00380 4.4e-68 yqhL P Rhodanese-like protein
IIPKEOGD_00381 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
IIPKEOGD_00382 5.7e-180 glk 2.7.1.2 G Glucokinase
IIPKEOGD_00383 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
IIPKEOGD_00384 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
IIPKEOGD_00385 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IIPKEOGD_00386 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IIPKEOGD_00387 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IIPKEOGD_00388 0.0 S membrane
IIPKEOGD_00389 1.5e-54 yneR S Belongs to the HesB IscA family
IIPKEOGD_00390 4e-75 XK27_02470 K LytTr DNA-binding domain
IIPKEOGD_00391 2.3e-96 liaI S membrane
IIPKEOGD_00392 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIPKEOGD_00393 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
IIPKEOGD_00394 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IIPKEOGD_00395 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIPKEOGD_00396 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IIPKEOGD_00397 1.1e-62 yodB K Transcriptional regulator, HxlR family
IIPKEOGD_00398 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
IIPKEOGD_00399 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IIPKEOGD_00400 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IIPKEOGD_00401 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIPKEOGD_00402 9.3e-93 S SdpI/YhfL protein family
IIPKEOGD_00403 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
IIPKEOGD_00404 0.0 sbcC L Putative exonuclease SbcCD, C subunit
IIPKEOGD_00405 5.8e-172 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IIPKEOGD_00406 8e-307 arlS 2.7.13.3 T Histidine kinase
IIPKEOGD_00407 4.3e-121 K response regulator
IIPKEOGD_00408 1.2e-244 rarA L recombination factor protein RarA
IIPKEOGD_00409 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IIPKEOGD_00410 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIPKEOGD_00411 7e-88 S Peptidase propeptide and YPEB domain
IIPKEOGD_00412 1.6e-97 yceD S Uncharacterized ACR, COG1399
IIPKEOGD_00413 3.4e-219 ylbM S Belongs to the UPF0348 family
IIPKEOGD_00414 4.4e-140 yqeM Q Methyltransferase
IIPKEOGD_00415 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IIPKEOGD_00416 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IIPKEOGD_00417 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IIPKEOGD_00418 1.1e-50 yhbY J RNA-binding protein
IIPKEOGD_00419 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
IIPKEOGD_00420 1.4e-98 yqeG S HAD phosphatase, family IIIA
IIPKEOGD_00421 1.3e-79
IIPKEOGD_00422 6.9e-222 pgaC GT2 M Glycosyl transferase
IIPKEOGD_00423 2.2e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
IIPKEOGD_00424 1e-62 hxlR K Transcriptional regulator, HxlR family
IIPKEOGD_00425 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IIPKEOGD_00426 5e-240 yrvN L AAA C-terminal domain
IIPKEOGD_00427 1.1e-55
IIPKEOGD_00428 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IIPKEOGD_00429 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IIPKEOGD_00430 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IIPKEOGD_00431 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IIPKEOGD_00432 1.2e-171 dnaI L Primosomal protein DnaI
IIPKEOGD_00433 1.1e-248 dnaB L replication initiation and membrane attachment
IIPKEOGD_00434 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IIPKEOGD_00435 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IIPKEOGD_00436 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IIPKEOGD_00437 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IIPKEOGD_00438 4.5e-121 ybhL S Belongs to the BI1 family
IIPKEOGD_00439 3.1e-111 hipB K Helix-turn-helix
IIPKEOGD_00440 5.5e-45 yitW S Iron-sulfur cluster assembly protein
IIPKEOGD_00441 1.4e-272 sufB O assembly protein SufB
IIPKEOGD_00442 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
IIPKEOGD_00443 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IIPKEOGD_00444 2.6e-244 sufD O FeS assembly protein SufD
IIPKEOGD_00445 4.2e-144 sufC O FeS assembly ATPase SufC
IIPKEOGD_00446 1.3e-34 feoA P FeoA domain
IIPKEOGD_00447 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
IIPKEOGD_00448 7.9e-21 S Virus attachment protein p12 family
IIPKEOGD_00449 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IIPKEOGD_00450 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
IIPKEOGD_00452 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IIPKEOGD_00453 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
IIPKEOGD_00454 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IIPKEOGD_00455 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
IIPKEOGD_00456 6.2e-224 ecsB U ABC transporter
IIPKEOGD_00457 1.6e-134 ecsA V ABC transporter, ATP-binding protein
IIPKEOGD_00458 9.9e-82 hit FG histidine triad
IIPKEOGD_00459 2e-42
IIPKEOGD_00460 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIPKEOGD_00461 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
IIPKEOGD_00462 3.5e-78 S WxL domain surface cell wall-binding
IIPKEOGD_00463 4e-103 S WxL domain surface cell wall-binding
IIPKEOGD_00464 9.3e-192 S Fn3-like domain
IIPKEOGD_00465 3.5e-61
IIPKEOGD_00466 0.0
IIPKEOGD_00467 2.1e-241 npr 1.11.1.1 C NADH oxidase
IIPKEOGD_00468 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPKEOGD_00469 9.8e-28
IIPKEOGD_00470 8.4e-145 yjfP S Dienelactone hydrolase family
IIPKEOGD_00471 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
IIPKEOGD_00472 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
IIPKEOGD_00473 5.2e-47
IIPKEOGD_00474 1.7e-45
IIPKEOGD_00475 5e-82 yybC S Protein of unknown function (DUF2798)
IIPKEOGD_00476 3.7e-73
IIPKEOGD_00477 4e-60
IIPKEOGD_00478 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
IIPKEOGD_00479 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
IIPKEOGD_00480 1.6e-79 uspA T universal stress protein
IIPKEOGD_00481 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IIPKEOGD_00482 1.7e-48 K Cro/C1-type HTH DNA-binding domain
IIPKEOGD_00483 3.3e-21 S Protein of unknown function (DUF2929)
IIPKEOGD_00484 2.3e-223 lsgC M Glycosyl transferases group 1
IIPKEOGD_00485 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IIPKEOGD_00486 2.3e-164 S Putative esterase
IIPKEOGD_00487 2.4e-130 gntR2 K Transcriptional regulator
IIPKEOGD_00488 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IIPKEOGD_00489 1.5e-138
IIPKEOGD_00490 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IIPKEOGD_00491 5.5e-138 rrp8 K LytTr DNA-binding domain
IIPKEOGD_00492 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
IIPKEOGD_00493 7.7e-61
IIPKEOGD_00494 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
IIPKEOGD_00495 4.4e-58
IIPKEOGD_00496 1.2e-239 yhdP S Transporter associated domain
IIPKEOGD_00497 4.9e-87 nrdI F Belongs to the NrdI family
IIPKEOGD_00498 2.9e-269 yjcE P Sodium proton antiporter
IIPKEOGD_00499 2.8e-213 yttB EGP Major facilitator Superfamily
IIPKEOGD_00500 5e-63 K helix_turn_helix, mercury resistance
IIPKEOGD_00501 3e-30 C Zinc-binding dehydrogenase
IIPKEOGD_00502 1.9e-127 C Zinc-binding dehydrogenase
IIPKEOGD_00503 8.5e-57 S SdpI/YhfL protein family
IIPKEOGD_00504 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IIPKEOGD_00505 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
IIPKEOGD_00506 5e-218 patA 2.6.1.1 E Aminotransferase
IIPKEOGD_00507 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIPKEOGD_00508 3e-18
IIPKEOGD_00509 1.7e-126 S membrane transporter protein
IIPKEOGD_00510 7.3e-161 mleR K LysR family
IIPKEOGD_00511 5.6e-115 ylbE GM NAD(P)H-binding
IIPKEOGD_00512 8.2e-96 wecD K Acetyltransferase (GNAT) family
IIPKEOGD_00513 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IIPKEOGD_00514 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IIPKEOGD_00515 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
IIPKEOGD_00516 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IIPKEOGD_00517 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IIPKEOGD_00518 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IIPKEOGD_00519 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IIPKEOGD_00520 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IIPKEOGD_00521 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IIPKEOGD_00522 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IIPKEOGD_00523 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IIPKEOGD_00524 1e-298 pucR QT Purine catabolism regulatory protein-like family
IIPKEOGD_00525 2.7e-236 pbuX F xanthine permease
IIPKEOGD_00526 2.4e-221 pbuG S Permease family
IIPKEOGD_00527 5.6e-161 GM NmrA-like family
IIPKEOGD_00528 6.5e-156 T EAL domain
IIPKEOGD_00529 2.6e-94
IIPKEOGD_00530 9.2e-253 pgaC GT2 M Glycosyl transferase
IIPKEOGD_00531 1e-122 2.1.1.14 E Methionine synthase
IIPKEOGD_00532 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
IIPKEOGD_00533 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
IIPKEOGD_00534 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IIPKEOGD_00535 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
IIPKEOGD_00536 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IIPKEOGD_00537 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPKEOGD_00538 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPKEOGD_00539 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IIPKEOGD_00540 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
IIPKEOGD_00541 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IIPKEOGD_00542 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IIPKEOGD_00543 4.3e-223 XK27_09615 1.3.5.4 S reductase
IIPKEOGD_00544 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
IIPKEOGD_00545 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
IIPKEOGD_00546 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
IIPKEOGD_00547 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
IIPKEOGD_00548 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_00549 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
IIPKEOGD_00550 1.7e-139 cysA V ABC transporter, ATP-binding protein
IIPKEOGD_00551 0.0 V FtsX-like permease family
IIPKEOGD_00552 7.4e-40
IIPKEOGD_00553 7.9e-61 gntR1 K Transcriptional regulator, GntR family
IIPKEOGD_00554 6.9e-164 V ABC transporter, ATP-binding protein
IIPKEOGD_00555 5.1e-137
IIPKEOGD_00556 1.9e-80 uspA T universal stress protein
IIPKEOGD_00557 4e-34
IIPKEOGD_00558 5.5e-71 gtcA S Teichoic acid glycosylation protein
IIPKEOGD_00559 1.1e-88
IIPKEOGD_00560 3.2e-50
IIPKEOGD_00562 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
IIPKEOGD_00563 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
IIPKEOGD_00564 5.4e-118
IIPKEOGD_00565 1.5e-52
IIPKEOGD_00567 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IIPKEOGD_00568 1.1e-281 thrC 4.2.3.1 E Threonine synthase
IIPKEOGD_00569 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
IIPKEOGD_00570 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
IIPKEOGD_00571 2.5e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IIPKEOGD_00572 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
IIPKEOGD_00573 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
IIPKEOGD_00574 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
IIPKEOGD_00575 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
IIPKEOGD_00576 1.4e-211 S Bacterial protein of unknown function (DUF871)
IIPKEOGD_00577 2.1e-232 S Sterol carrier protein domain
IIPKEOGD_00578 3.6e-88 niaR S 3H domain
IIPKEOGD_00579 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IIPKEOGD_00580 2.8e-117 K Transcriptional regulator
IIPKEOGD_00581 1.1e-151 V ABC transporter
IIPKEOGD_00582 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
IIPKEOGD_00583 4.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
IIPKEOGD_00584 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_00585 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_00586 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
IIPKEOGD_00587 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_00588 9.9e-129 gntR K UTRA
IIPKEOGD_00589 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
IIPKEOGD_00590 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IIPKEOGD_00591 1.8e-81
IIPKEOGD_00592 9.8e-152 S hydrolase
IIPKEOGD_00593 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIPKEOGD_00594 1.4e-151 EG EamA-like transporter family
IIPKEOGD_00595 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
IIPKEOGD_00596 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IIPKEOGD_00597 6.5e-232
IIPKEOGD_00598 4.2e-77 fld C Flavodoxin
IIPKEOGD_00599 0.0 M Bacterial Ig-like domain (group 3)
IIPKEOGD_00600 6.2e-149 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IIPKEOGD_00601 4.1e-283 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
IIPKEOGD_00602 2.7e-32
IIPKEOGD_00603 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
IIPKEOGD_00604 6.4e-268 ycaM E amino acid
IIPKEOGD_00605 8.7e-78 K Winged helix DNA-binding domain
IIPKEOGD_00606 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
IIPKEOGD_00607 1.1e-161 akr5f 1.1.1.346 S reductase
IIPKEOGD_00608 3.9e-162 K Transcriptional regulator
IIPKEOGD_00610 1.6e-75 yugI 5.3.1.9 J general stress protein
IIPKEOGD_00611 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IIPKEOGD_00612 1.9e-118 dedA S SNARE-like domain protein
IIPKEOGD_00613 1.8e-116 S Protein of unknown function (DUF1461)
IIPKEOGD_00614 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IIPKEOGD_00615 1.5e-80 yutD S Protein of unknown function (DUF1027)
IIPKEOGD_00616 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IIPKEOGD_00617 4.4e-117 S Calcineurin-like phosphoesterase
IIPKEOGD_00618 5.3e-251 cycA E Amino acid permease
IIPKEOGD_00619 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIPKEOGD_00620 4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
IIPKEOGD_00622 4.5e-88 S Prokaryotic N-terminal methylation motif
IIPKEOGD_00623 8.6e-20
IIPKEOGD_00624 3.2e-83 gspG NU general secretion pathway protein
IIPKEOGD_00625 5.5e-43 comGC U competence protein ComGC
IIPKEOGD_00626 1.9e-189 comGB NU type II secretion system
IIPKEOGD_00627 2.1e-174 comGA NU Type II IV secretion system protein
IIPKEOGD_00628 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIPKEOGD_00629 8.3e-131 yebC K Transcriptional regulatory protein
IIPKEOGD_00630 1.6e-49 S DsrE/DsrF-like family
IIPKEOGD_00631 6.8e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
IIPKEOGD_00632 1.9e-181 ccpA K catabolite control protein A
IIPKEOGD_00633 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IIPKEOGD_00634 1.9e-62 K helix_turn_helix, mercury resistance
IIPKEOGD_00635 2.8e-56
IIPKEOGD_00636 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IIPKEOGD_00637 2.6e-158 ykuT M mechanosensitive ion channel
IIPKEOGD_00638 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IIPKEOGD_00639 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IIPKEOGD_00640 6.5e-87 ykuL S (CBS) domain
IIPKEOGD_00641 9.5e-97 S Phosphoesterase
IIPKEOGD_00642 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IIPKEOGD_00643 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IIPKEOGD_00644 7.6e-126 yslB S Protein of unknown function (DUF2507)
IIPKEOGD_00645 3.3e-52 trxA O Belongs to the thioredoxin family
IIPKEOGD_00646 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IIPKEOGD_00647 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
IIPKEOGD_00648 1.6e-48 yrzB S Belongs to the UPF0473 family
IIPKEOGD_00649 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IIPKEOGD_00650 2.4e-43 yrzL S Belongs to the UPF0297 family
IIPKEOGD_00651 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IIPKEOGD_00652 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IIPKEOGD_00653 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IIPKEOGD_00654 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IIPKEOGD_00655 2.8e-29 yajC U Preprotein translocase
IIPKEOGD_00656 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
IIPKEOGD_00657 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IIPKEOGD_00658 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IIPKEOGD_00659 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IIPKEOGD_00660 9.6e-89
IIPKEOGD_00661 0.0 S Bacterial membrane protein YfhO
IIPKEOGD_00662 3.1e-71
IIPKEOGD_00663 0.0 L Transposase
IIPKEOGD_00664 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IIPKEOGD_00665 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IIPKEOGD_00666 2.7e-154 ymdB S YmdB-like protein
IIPKEOGD_00667 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
IIPKEOGD_00668 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IIPKEOGD_00669 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
IIPKEOGD_00670 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IIPKEOGD_00671 5.7e-110 ymfM S Helix-turn-helix domain
IIPKEOGD_00672 2.9e-251 ymfH S Peptidase M16
IIPKEOGD_00673 1.9e-231 ymfF S Peptidase M16 inactive domain protein
IIPKEOGD_00674 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
IIPKEOGD_00675 1.5e-155 aatB ET ABC transporter substrate-binding protein
IIPKEOGD_00676 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_00677 4.6e-109 glnP P ABC transporter permease
IIPKEOGD_00678 1.2e-146 minD D Belongs to the ParA family
IIPKEOGD_00679 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
IIPKEOGD_00680 1.2e-88 mreD M rod shape-determining protein MreD
IIPKEOGD_00681 2.6e-144 mreC M Involved in formation and maintenance of cell shape
IIPKEOGD_00682 2.8e-161 mreB D cell shape determining protein MreB
IIPKEOGD_00683 1.3e-116 radC L DNA repair protein
IIPKEOGD_00684 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIPKEOGD_00685 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IIPKEOGD_00686 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IIPKEOGD_00687 1.2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IIPKEOGD_00688 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IIPKEOGD_00689 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
IIPKEOGD_00691 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IIPKEOGD_00692 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
IIPKEOGD_00693 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IIPKEOGD_00694 5.2e-113 yktB S Belongs to the UPF0637 family
IIPKEOGD_00695 7.3e-80 yueI S Protein of unknown function (DUF1694)
IIPKEOGD_00696 2.2e-108 S Protein of unknown function (DUF1648)
IIPKEOGD_00697 1.9e-43 czrA K Helix-turn-helix domain
IIPKEOGD_00698 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
IIPKEOGD_00699 8e-238 rarA L recombination factor protein RarA
IIPKEOGD_00700 1.5e-38
IIPKEOGD_00701 6.2e-82 usp6 T universal stress protein
IIPKEOGD_00702 6.3e-202 bla2 3.5.2.6 V Beta-lactamase enzyme family
IIPKEOGD_00703 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_00704 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
IIPKEOGD_00705 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IIPKEOGD_00706 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
IIPKEOGD_00707 1.6e-177 S Protein of unknown function (DUF2785)
IIPKEOGD_00708 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
IIPKEOGD_00709 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
IIPKEOGD_00710 1.4e-111 metI U ABC transporter permease
IIPKEOGD_00711 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIPKEOGD_00712 3.6e-48 gcsH2 E glycine cleavage
IIPKEOGD_00713 9.3e-220 rodA D Belongs to the SEDS family
IIPKEOGD_00714 1.2e-32 S Protein of unknown function (DUF2969)
IIPKEOGD_00715 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IIPKEOGD_00716 2.7e-180 mbl D Cell shape determining protein MreB Mrl
IIPKEOGD_00717 2.1e-102 J Acetyltransferase (GNAT) domain
IIPKEOGD_00718 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIPKEOGD_00719 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IIPKEOGD_00720 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IIPKEOGD_00721 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IIPKEOGD_00722 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IIPKEOGD_00723 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIPKEOGD_00724 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IIPKEOGD_00725 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IIPKEOGD_00726 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IIPKEOGD_00727 3e-232 pyrP F Permease
IIPKEOGD_00728 3.4e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
IIPKEOGD_00729 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IIPKEOGD_00730 1.3e-128 K Helix-turn-helix domain, rpiR family
IIPKEOGD_00731 8.5e-159 S Alpha beta hydrolase
IIPKEOGD_00732 9.9e-112 GM NmrA-like family
IIPKEOGD_00733 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
IIPKEOGD_00734 1.9e-161 K Transcriptional regulator
IIPKEOGD_00735 1.9e-172 C nadph quinone reductase
IIPKEOGD_00736 6.3e-14 S Alpha beta hydrolase
IIPKEOGD_00737 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
IIPKEOGD_00738 4e-102 desR K helix_turn_helix, Lux Regulon
IIPKEOGD_00739 2.8e-207 desK 2.7.13.3 T Histidine kinase
IIPKEOGD_00740 3.1e-136 yvfS V ABC-2 type transporter
IIPKEOGD_00741 5.2e-159 yvfR V ABC transporter
IIPKEOGD_00743 6e-82 K Acetyltransferase (GNAT) domain
IIPKEOGD_00744 2.4e-72 K MarR family
IIPKEOGD_00745 3.8e-114 S Psort location CytoplasmicMembrane, score
IIPKEOGD_00746 2.6e-12 yjdF S Protein of unknown function (DUF2992)
IIPKEOGD_00747 5.6e-161 V ABC transporter, ATP-binding protein
IIPKEOGD_00748 5.2e-128 S ABC-2 family transporter protein
IIPKEOGD_00749 1.5e-197
IIPKEOGD_00750 5.9e-202
IIPKEOGD_00751 4.8e-165 ytrB V ABC transporter, ATP-binding protein
IIPKEOGD_00752 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
IIPKEOGD_00753 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IIPKEOGD_00754 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IIPKEOGD_00755 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IIPKEOGD_00756 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IIPKEOGD_00757 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
IIPKEOGD_00758 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IIPKEOGD_00759 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
IIPKEOGD_00760 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IIPKEOGD_00761 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
IIPKEOGD_00762 2.6e-71 yqeY S YqeY-like protein
IIPKEOGD_00763 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IIPKEOGD_00764 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IIPKEOGD_00765 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
IIPKEOGD_00766 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IIPKEOGD_00767 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPKEOGD_00768 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IIPKEOGD_00769 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIPKEOGD_00770 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IIPKEOGD_00771 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
IIPKEOGD_00772 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
IIPKEOGD_00773 1.6e-160 yniA G Fructosamine kinase
IIPKEOGD_00774 6.5e-116 3.1.3.18 J HAD-hyrolase-like
IIPKEOGD_00775 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IIPKEOGD_00776 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IIPKEOGD_00777 9.6e-58
IIPKEOGD_00778 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
IIPKEOGD_00779 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
IIPKEOGD_00780 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IIPKEOGD_00781 1.4e-49
IIPKEOGD_00782 1.4e-49
IIPKEOGD_00785 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
IIPKEOGD_00786 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIPKEOGD_00787 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IIPKEOGD_00788 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPKEOGD_00789 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
IIPKEOGD_00790 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPKEOGD_00791 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
IIPKEOGD_00792 4.4e-198 pbpX2 V Beta-lactamase
IIPKEOGD_00793 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IIPKEOGD_00794 0.0 dnaK O Heat shock 70 kDa protein
IIPKEOGD_00795 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IIPKEOGD_00796 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IIPKEOGD_00797 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
IIPKEOGD_00798 1.7e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IIPKEOGD_00799 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IIPKEOGD_00800 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IIPKEOGD_00801 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
IIPKEOGD_00802 2.5e-223 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
IIPKEOGD_00803 8.5e-93
IIPKEOGD_00804 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IIPKEOGD_00805 2e-264 ydiN 5.4.99.5 G Major Facilitator
IIPKEOGD_00806 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IIPKEOGD_00807 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IIPKEOGD_00808 3.1e-47 ylxQ J ribosomal protein
IIPKEOGD_00809 9.5e-49 ylxR K Protein of unknown function (DUF448)
IIPKEOGD_00810 3.3e-217 nusA K Participates in both transcription termination and antitermination
IIPKEOGD_00811 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
IIPKEOGD_00812 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IIPKEOGD_00813 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IIPKEOGD_00814 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IIPKEOGD_00815 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
IIPKEOGD_00816 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IIPKEOGD_00817 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IIPKEOGD_00818 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IIPKEOGD_00819 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IIPKEOGD_00820 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
IIPKEOGD_00821 4.7e-134 S Haloacid dehalogenase-like hydrolase
IIPKEOGD_00822 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPKEOGD_00823 7e-39 yazA L GIY-YIG catalytic domain protein
IIPKEOGD_00824 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
IIPKEOGD_00825 6.4e-119 plsC 2.3.1.51 I Acyltransferase
IIPKEOGD_00826 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
IIPKEOGD_00827 2.9e-36 ynzC S UPF0291 protein
IIPKEOGD_00828 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IIPKEOGD_00829 3.7e-87
IIPKEOGD_00830 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IIPKEOGD_00831 4.6e-75
IIPKEOGD_00832 3e-66
IIPKEOGD_00833 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
IIPKEOGD_00834 9.2e-101 L Helix-turn-helix domain
IIPKEOGD_00835 2.4e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
IIPKEOGD_00836 7.9e-143 P ATPases associated with a variety of cellular activities
IIPKEOGD_00837 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
IIPKEOGD_00838 2.2e-229 rodA D Cell cycle protein
IIPKEOGD_00840 4e-65 padC Q Phenolic acid decarboxylase
IIPKEOGD_00841 6.7e-142 tesE Q hydratase
IIPKEOGD_00842 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
IIPKEOGD_00843 2.8e-157 degV S DegV family
IIPKEOGD_00844 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
IIPKEOGD_00845 1.5e-255 pepC 3.4.22.40 E aminopeptidase
IIPKEOGD_00847 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIPKEOGD_00848 1.1e-302
IIPKEOGD_00850 3e-158 S Bacterial protein of unknown function (DUF916)
IIPKEOGD_00851 5.9e-92 S Cell surface protein
IIPKEOGD_00852 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IIPKEOGD_00853 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IIPKEOGD_00854 9.1e-109 jag S R3H domain protein
IIPKEOGD_00855 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
IIPKEOGD_00856 1e-309 E ABC transporter, substratebinding protein
IIPKEOGD_00857 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IIPKEOGD_00858 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IIPKEOGD_00859 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IIPKEOGD_00860 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IIPKEOGD_00861 5e-37 yaaA S S4 domain protein YaaA
IIPKEOGD_00862 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IIPKEOGD_00863 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIPKEOGD_00864 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IIPKEOGD_00865 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IIPKEOGD_00866 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IIPKEOGD_00867 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IIPKEOGD_00868 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IIPKEOGD_00869 1.4e-67 rplI J Binds to the 23S rRNA
IIPKEOGD_00870 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IIPKEOGD_00871 8.8e-226 yttB EGP Major facilitator Superfamily
IIPKEOGD_00872 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IIPKEOGD_00873 1.2e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IIPKEOGD_00875 4.2e-276 E ABC transporter, substratebinding protein
IIPKEOGD_00876 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
IIPKEOGD_00877 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IIPKEOGD_00878 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
IIPKEOGD_00879 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
IIPKEOGD_00880 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
IIPKEOGD_00881 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
IIPKEOGD_00882 4.5e-143 S haloacid dehalogenase-like hydrolase
IIPKEOGD_00883 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IIPKEOGD_00884 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
IIPKEOGD_00885 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
IIPKEOGD_00886 1.6e-31 cspA K Cold shock protein domain
IIPKEOGD_00887 1.7e-37
IIPKEOGD_00889 6.2e-131 K response regulator
IIPKEOGD_00890 0.0 vicK 2.7.13.3 T Histidine kinase
IIPKEOGD_00891 1.2e-244 yycH S YycH protein
IIPKEOGD_00892 2.2e-151 yycI S YycH protein
IIPKEOGD_00893 8.9e-158 vicX 3.1.26.11 S domain protein
IIPKEOGD_00894 6.8e-173 htrA 3.4.21.107 O serine protease
IIPKEOGD_00895 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IIPKEOGD_00896 1.5e-95 K Bacterial regulatory proteins, tetR family
IIPKEOGD_00897 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
IIPKEOGD_00898 7.2e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
IIPKEOGD_00899 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
IIPKEOGD_00900 4.2e-32 pnb C nitroreductase
IIPKEOGD_00901 5.7e-67 pnb C nitroreductase
IIPKEOGD_00902 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IIPKEOGD_00903 1.8e-116 S Elongation factor G-binding protein, N-terminal
IIPKEOGD_00904 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
IIPKEOGD_00905 1.3e-257 P Sodium:sulfate symporter transmembrane region
IIPKEOGD_00906 5.7e-158 K LysR family
IIPKEOGD_00907 1e-72 C FMN binding
IIPKEOGD_00908 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IIPKEOGD_00909 2.3e-164 ptlF S KR domain
IIPKEOGD_00910 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
IIPKEOGD_00911 1.3e-122 drgA C Nitroreductase family
IIPKEOGD_00912 1.3e-290 QT PucR C-terminal helix-turn-helix domain
IIPKEOGD_00913 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IIPKEOGD_00914 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIPKEOGD_00915 7.4e-250 yjjP S Putative threonine/serine exporter
IIPKEOGD_00916 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
IIPKEOGD_00917 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
IIPKEOGD_00918 2.9e-81 6.3.3.2 S ASCH
IIPKEOGD_00919 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
IIPKEOGD_00920 5.5e-172 yobV1 K WYL domain
IIPKEOGD_00921 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIPKEOGD_00922 0.0 tetP J elongation factor G
IIPKEOGD_00923 8.2e-39 S Protein of unknown function
IIPKEOGD_00924 2.1e-61 S Protein of unknown function
IIPKEOGD_00925 8e-152 EG EamA-like transporter family
IIPKEOGD_00926 3.6e-93 MA20_25245 K FR47-like protein
IIPKEOGD_00927 2e-126 hchA S DJ-1/PfpI family
IIPKEOGD_00928 5.4e-181 1.1.1.1 C nadph quinone reductase
IIPKEOGD_00929 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_00930 2.3e-235 mepA V MATE efflux family protein
IIPKEOGD_00931 6.4e-156 pelX UW LPXTG-motif cell wall anchor domain protein
IIPKEOGD_00932 5.3e-86
IIPKEOGD_00933 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
IIPKEOGD_00934 1.5e-270 XK27_00765
IIPKEOGD_00936 5.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
IIPKEOGD_00937 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
IIPKEOGD_00938 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IIPKEOGD_00939 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
IIPKEOGD_00940 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
IIPKEOGD_00941 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
IIPKEOGD_00942 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
IIPKEOGD_00943 2e-97 entB 3.5.1.19 Q Isochorismatase family
IIPKEOGD_00944 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
IIPKEOGD_00945 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
IIPKEOGD_00946 5.8e-217 E glutamate:sodium symporter activity
IIPKEOGD_00947 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
IIPKEOGD_00948 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IIPKEOGD_00949 2.1e-58 S Protein of unknown function (DUF1648)
IIPKEOGD_00951 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPKEOGD_00952 1.1e-178 yneE K Transcriptional regulator
IIPKEOGD_00953 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
IIPKEOGD_00954 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IIPKEOGD_00955 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IIPKEOGD_00956 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IIPKEOGD_00957 2.1e-126 IQ reductase
IIPKEOGD_00958 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IIPKEOGD_00959 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIPKEOGD_00960 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IIPKEOGD_00961 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IIPKEOGD_00962 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IIPKEOGD_00963 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IIPKEOGD_00964 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IIPKEOGD_00965 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
IIPKEOGD_00966 2.2e-123 S Protein of unknown function (DUF554)
IIPKEOGD_00967 1.6e-160 K LysR substrate binding domain
IIPKEOGD_00968 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
IIPKEOGD_00969 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IIPKEOGD_00970 7.5e-92 K transcriptional regulator
IIPKEOGD_00971 1.4e-301 norB EGP Major Facilitator
IIPKEOGD_00972 1.2e-139 f42a O Band 7 protein
IIPKEOGD_00973 8.5e-54
IIPKEOGD_00974 1.3e-28
IIPKEOGD_00975 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IIPKEOGD_00976 2.3e-29 L hmm pf00665
IIPKEOGD_00977 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
IIPKEOGD_00978 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
IIPKEOGD_00979 7.9e-41
IIPKEOGD_00980 1.9e-67 tspO T TspO/MBR family
IIPKEOGD_00981 6.3e-76 uspA T Belongs to the universal stress protein A family
IIPKEOGD_00982 1e-65 S Protein of unknown function (DUF805)
IIPKEOGD_00983 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
IIPKEOGD_00984 2.9e-35
IIPKEOGD_00985 3.1e-14
IIPKEOGD_00986 6.5e-41 S transglycosylase associated protein
IIPKEOGD_00987 4.8e-29 S CsbD-like
IIPKEOGD_00988 9.4e-40
IIPKEOGD_00989 8.6e-281 pipD E Dipeptidase
IIPKEOGD_00990 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IIPKEOGD_00991 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IIPKEOGD_00992 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
IIPKEOGD_00993 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
IIPKEOGD_00994 1.9e-49
IIPKEOGD_00995 2.4e-43
IIPKEOGD_00996 3.3e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IIPKEOGD_00997 1.4e-265 yfnA E Amino Acid
IIPKEOGD_00998 1.2e-149 yitU 3.1.3.104 S hydrolase
IIPKEOGD_00999 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
IIPKEOGD_01000 1.5e-89 S Domain of unknown function (DUF4767)
IIPKEOGD_01001 2.5e-250 malT G Major Facilitator
IIPKEOGD_01002 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IIPKEOGD_01003 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IIPKEOGD_01004 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IIPKEOGD_01005 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IIPKEOGD_01006 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IIPKEOGD_01007 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
IIPKEOGD_01008 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IIPKEOGD_01009 2.1e-72 ypmB S protein conserved in bacteria
IIPKEOGD_01010 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
IIPKEOGD_01011 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IIPKEOGD_01012 1.1e-127 dnaD L Replication initiation and membrane attachment
IIPKEOGD_01014 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IIPKEOGD_01015 2e-99 metI P ABC transporter permease
IIPKEOGD_01016 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
IIPKEOGD_01017 1.7e-82 uspA T Universal stress protein family
IIPKEOGD_01018 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
IIPKEOGD_01019 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
IIPKEOGD_01020 7e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
IIPKEOGD_01021 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IIPKEOGD_01022 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IIPKEOGD_01023 8.3e-110 ypsA S Belongs to the UPF0398 family
IIPKEOGD_01024 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IIPKEOGD_01026 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IIPKEOGD_01027 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_01028 6.1e-244 P Major Facilitator Superfamily
IIPKEOGD_01029 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
IIPKEOGD_01030 1.7e-72 S SnoaL-like domain
IIPKEOGD_01031 2.8e-241 M Glycosyltransferase, group 2 family protein
IIPKEOGD_01032 5.1e-209 mccF V LD-carboxypeptidase
IIPKEOGD_01033 1.4e-78 K Acetyltransferase (GNAT) domain
IIPKEOGD_01034 1e-106
IIPKEOGD_01035 1.4e-117 S Domain of unknown function (DUF4811)
IIPKEOGD_01036 7e-270 lmrB EGP Major facilitator Superfamily
IIPKEOGD_01037 1.7e-84 merR K MerR HTH family regulatory protein
IIPKEOGD_01038 2.6e-58
IIPKEOGD_01039 2e-120 sirR K iron dependent repressor
IIPKEOGD_01040 6e-31 cspC K Cold shock protein
IIPKEOGD_01041 1.5e-130 thrE S Putative threonine/serine exporter
IIPKEOGD_01042 2.2e-76 S Threonine/Serine exporter, ThrE
IIPKEOGD_01043 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IIPKEOGD_01044 3.9e-119 lssY 3.6.1.27 I phosphatase
IIPKEOGD_01045 2e-154 I alpha/beta hydrolase fold
IIPKEOGD_01046 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
IIPKEOGD_01047 3.6e-91 K Transcriptional regulator
IIPKEOGD_01048 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
IIPKEOGD_01049 1.6e-263 lysP E amino acid
IIPKEOGD_01050 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
IIPKEOGD_01051 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IIPKEOGD_01052 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIPKEOGD_01059 6.9e-78 ctsR K Belongs to the CtsR family
IIPKEOGD_01060 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IIPKEOGD_01061 1.5e-109 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01062 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPKEOGD_01063 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPKEOGD_01064 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IIPKEOGD_01065 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IIPKEOGD_01066 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IIPKEOGD_01067 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IIPKEOGD_01068 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IIPKEOGD_01069 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IIPKEOGD_01070 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
IIPKEOGD_01071 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IIPKEOGD_01072 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IIPKEOGD_01073 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IIPKEOGD_01074 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IIPKEOGD_01075 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IIPKEOGD_01076 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IIPKEOGD_01077 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
IIPKEOGD_01078 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IIPKEOGD_01079 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IIPKEOGD_01080 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IIPKEOGD_01081 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IIPKEOGD_01082 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IIPKEOGD_01083 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IIPKEOGD_01084 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IIPKEOGD_01085 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IIPKEOGD_01086 2.2e-24 rpmD J Ribosomal protein L30
IIPKEOGD_01087 6.3e-70 rplO J Binds to the 23S rRNA
IIPKEOGD_01088 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IIPKEOGD_01089 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IIPKEOGD_01090 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IIPKEOGD_01091 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IIPKEOGD_01092 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IIPKEOGD_01093 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IIPKEOGD_01094 2.1e-61 rplQ J Ribosomal protein L17
IIPKEOGD_01095 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIPKEOGD_01096 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
IIPKEOGD_01097 7.2e-86 ynhH S NusG domain II
IIPKEOGD_01098 0.0 ndh 1.6.99.3 C NADH dehydrogenase
IIPKEOGD_01099 3.5e-142 cad S FMN_bind
IIPKEOGD_01100 4.4e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIPKEOGD_01101 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPKEOGD_01102 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPKEOGD_01103 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IIPKEOGD_01104 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IIPKEOGD_01105 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IIPKEOGD_01106 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
IIPKEOGD_01107 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
IIPKEOGD_01108 2.2e-173 ywhK S Membrane
IIPKEOGD_01109 5.5e-30 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IIPKEOGD_01110 1.5e-163 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IIPKEOGD_01111 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIPKEOGD_01112 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIPKEOGD_01113 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
IIPKEOGD_01114 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IIPKEOGD_01116 2.2e-221 P Sodium:sulfate symporter transmembrane region
IIPKEOGD_01117 4.1e-53 yitW S Iron-sulfur cluster assembly protein
IIPKEOGD_01118 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
IIPKEOGD_01119 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
IIPKEOGD_01120 7.2e-197 K Helix-turn-helix domain
IIPKEOGD_01121 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IIPKEOGD_01122 4.5e-132 mntB 3.6.3.35 P ABC transporter
IIPKEOGD_01123 8.2e-141 mtsB U ABC 3 transport family
IIPKEOGD_01124 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
IIPKEOGD_01125 3.1e-50
IIPKEOGD_01126 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IIPKEOGD_01127 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
IIPKEOGD_01128 2.9e-179 citR K sugar-binding domain protein
IIPKEOGD_01129 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
IIPKEOGD_01130 1.7e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IIPKEOGD_01131 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
IIPKEOGD_01132 9.7e-161 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IIPKEOGD_01133 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IIPKEOGD_01134 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIPKEOGD_01135 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
IIPKEOGD_01136 1.1e-225 patA 2.6.1.1 E Aminotransferase
IIPKEOGD_01137 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIPKEOGD_01138 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IIPKEOGD_01139 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
IIPKEOGD_01140 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
IIPKEOGD_01141 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IIPKEOGD_01142 2.7e-39 ptsH G phosphocarrier protein HPR
IIPKEOGD_01143 6.5e-30
IIPKEOGD_01144 0.0 clpE O Belongs to the ClpA ClpB family
IIPKEOGD_01145 2.2e-73 L Integrase
IIPKEOGD_01146 1e-63 K Winged helix DNA-binding domain
IIPKEOGD_01147 1.8e-181 oppF P Belongs to the ABC transporter superfamily
IIPKEOGD_01148 9.2e-203 oppD P Belongs to the ABC transporter superfamily
IIPKEOGD_01149 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPKEOGD_01150 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IIPKEOGD_01151 1.3e-309 oppA E ABC transporter, substratebinding protein
IIPKEOGD_01152 3.2e-57 ywjH S Protein of unknown function (DUF1634)
IIPKEOGD_01153 5.5e-126 yxaA S membrane transporter protein
IIPKEOGD_01154 7.1e-161 lysR5 K LysR substrate binding domain
IIPKEOGD_01155 2.7e-196 M MucBP domain
IIPKEOGD_01156 1.7e-273
IIPKEOGD_01157 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IIPKEOGD_01158 2.4e-253 gor 1.8.1.7 C Glutathione reductase
IIPKEOGD_01159 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
IIPKEOGD_01160 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
IIPKEOGD_01161 9.5e-213 gntP EG Gluconate
IIPKEOGD_01162 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IIPKEOGD_01163 9.3e-188 yueF S AI-2E family transporter
IIPKEOGD_01164 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IIPKEOGD_01165 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
IIPKEOGD_01166 7.8e-48 K sequence-specific DNA binding
IIPKEOGD_01167 2.5e-133 cwlO M NlpC/P60 family
IIPKEOGD_01168 4.1e-106 ygaC J Belongs to the UPF0374 family
IIPKEOGD_01169 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
IIPKEOGD_01170 3e-125
IIPKEOGD_01171 6.8e-101 K DNA-templated transcription, initiation
IIPKEOGD_01172 1.3e-25
IIPKEOGD_01173 7e-30
IIPKEOGD_01174 7.3e-33 S Protein of unknown function (DUF2922)
IIPKEOGD_01175 3.8e-53
IIPKEOGD_01176 2.2e-17 L Helix-turn-helix domain
IIPKEOGD_01177 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_01178 1.4e-154 yihY S Belongs to the UPF0761 family
IIPKEOGD_01179 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IIPKEOGD_01180 1.2e-219 pbpX1 V Beta-lactamase
IIPKEOGD_01181 8.4e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
IIPKEOGD_01182 1.4e-106
IIPKEOGD_01183 1.3e-73
IIPKEOGD_01185 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_01186 2.9e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_01187 2.3e-75 T Universal stress protein family
IIPKEOGD_01189 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
IIPKEOGD_01190 2.4e-189 mocA S Oxidoreductase
IIPKEOGD_01191 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
IIPKEOGD_01192 1.1e-62 S Domain of unknown function (DUF4828)
IIPKEOGD_01193 2e-143 lys M Glycosyl hydrolases family 25
IIPKEOGD_01194 2.3e-151 gntR K rpiR family
IIPKEOGD_01195 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_01196 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_01197 0.0 yfgQ P E1-E2 ATPase
IIPKEOGD_01198 6e-100 yobS K Bacterial regulatory proteins, tetR family
IIPKEOGD_01199 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIPKEOGD_01200 1e-190 yegS 2.7.1.107 G Lipid kinase
IIPKEOGD_01201 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIPKEOGD_01202 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IIPKEOGD_01203 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IIPKEOGD_01204 2.6e-198 camS S sex pheromone
IIPKEOGD_01205 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIPKEOGD_01206 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IIPKEOGD_01207 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
IIPKEOGD_01208 1e-93 S UPF0316 protein
IIPKEOGD_01209 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IIPKEOGD_01210 3.4e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
IIPKEOGD_01211 7.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
IIPKEOGD_01212 1.7e-63 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_01213 6.2e-50
IIPKEOGD_01214 4.3e-78
IIPKEOGD_01215 8.9e-23 L hmm pf00665
IIPKEOGD_01216 6.9e-29 L hmm pf00665
IIPKEOGD_01217 7.6e-46 L Helix-turn-helix domain
IIPKEOGD_01219 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
IIPKEOGD_01221 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IIPKEOGD_01222 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
IIPKEOGD_01223 2.5e-164 fabK 1.3.1.9 S Nitronate monooxygenase
IIPKEOGD_01224 0.0 helD 3.6.4.12 L DNA helicase
IIPKEOGD_01225 7.2e-110 dedA S SNARE associated Golgi protein
IIPKEOGD_01226 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
IIPKEOGD_01227 0.0 yjbQ P TrkA C-terminal domain protein
IIPKEOGD_01228 4.7e-125 pgm3 G Phosphoglycerate mutase family
IIPKEOGD_01229 5.5e-129 pgm3 G Phosphoglycerate mutase family
IIPKEOGD_01230 1.2e-26
IIPKEOGD_01231 1.3e-48 sugE U Multidrug resistance protein
IIPKEOGD_01232 2.9e-78 3.6.1.55 F NUDIX domain
IIPKEOGD_01233 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IIPKEOGD_01234 7.1e-98 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01235 3.8e-85 S membrane transporter protein
IIPKEOGD_01236 4.9e-210 EGP Major facilitator Superfamily
IIPKEOGD_01237 2.8e-70 K MarR family
IIPKEOGD_01238 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
IIPKEOGD_01239 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_01240 1.4e-245 steT E amino acid
IIPKEOGD_01241 6.1e-140 G YdjC-like protein
IIPKEOGD_01242 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IIPKEOGD_01243 1.4e-153 K CAT RNA binding domain
IIPKEOGD_01244 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IIPKEOGD_01245 4e-108 glnP P ABC transporter permease
IIPKEOGD_01246 1.6e-109 gluC P ABC transporter permease
IIPKEOGD_01247 7.8e-149 glnH ET ABC transporter substrate-binding protein
IIPKEOGD_01248 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_01250 3.6e-41
IIPKEOGD_01251 9.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPKEOGD_01252 3.2e-184 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IIPKEOGD_01253 1.7e-73 gph 3.1.3.18 S HAD hydrolase, family IA, variant
IIPKEOGD_01254 4.9e-148
IIPKEOGD_01255 7.1e-12 3.2.1.14 GH18
IIPKEOGD_01256 1.3e-81 zur P Belongs to the Fur family
IIPKEOGD_01257 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
IIPKEOGD_01258 1.8e-19
IIPKEOGD_01259 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IIPKEOGD_01260 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IIPKEOGD_01261 2.5e-88
IIPKEOGD_01262 1.1e-251 yfnA E Amino Acid
IIPKEOGD_01263 2.6e-46
IIPKEOGD_01264 1.1e-68 O OsmC-like protein
IIPKEOGD_01265 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IIPKEOGD_01266 0.0 oatA I Acyltransferase
IIPKEOGD_01267 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIPKEOGD_01268 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IIPKEOGD_01269 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPKEOGD_01270 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IIPKEOGD_01271 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPKEOGD_01272 1.2e-225 pbuG S permease
IIPKEOGD_01273 1.5e-19
IIPKEOGD_01274 1.2e-82 K Transcriptional regulator
IIPKEOGD_01275 2.5e-152 licD M LicD family
IIPKEOGD_01276 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IIPKEOGD_01277 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IIPKEOGD_01278 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IIPKEOGD_01279 3.6e-242 EGP Major facilitator Superfamily
IIPKEOGD_01280 2.5e-89 V VanZ like family
IIPKEOGD_01281 1.5e-33
IIPKEOGD_01282 1.9e-71 spxA 1.20.4.1 P ArsC family
IIPKEOGD_01284 2.1e-143
IIPKEOGD_01285 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIPKEOGD_01286 8.8e-154 G Transmembrane secretion effector
IIPKEOGD_01287 3e-131 1.5.1.39 C nitroreductase
IIPKEOGD_01288 3e-72
IIPKEOGD_01289 1.5e-52
IIPKEOGD_01290 1.2e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IIPKEOGD_01291 3.1e-104 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01292 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
IIPKEOGD_01293 4.5e-123 yliE T EAL domain
IIPKEOGD_01298 5.1e-08
IIPKEOGD_01303 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
IIPKEOGD_01304 8.9e-182 P secondary active sulfate transmembrane transporter activity
IIPKEOGD_01305 1.4e-95
IIPKEOGD_01306 2e-94 K Acetyltransferase (GNAT) domain
IIPKEOGD_01307 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
IIPKEOGD_01308 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
IIPKEOGD_01310 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
IIPKEOGD_01311 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
IIPKEOGD_01312 9.2e-256 mmuP E amino acid
IIPKEOGD_01313 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IIPKEOGD_01314 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_01315 1.6e-121
IIPKEOGD_01316 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IIPKEOGD_01317 5.5e-278 bmr3 EGP Major facilitator Superfamily
IIPKEOGD_01318 1.7e-18 N Cell shape-determining protein MreB
IIPKEOGD_01319 2.1e-139 N Cell shape-determining protein MreB
IIPKEOGD_01320 0.0 S Pfam Methyltransferase
IIPKEOGD_01321 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_01322 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_01323 4.2e-29
IIPKEOGD_01324 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
IIPKEOGD_01325 1.4e-124 3.6.1.27 I Acid phosphatase homologues
IIPKEOGD_01326 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIPKEOGD_01327 3e-301 ytgP S Polysaccharide biosynthesis protein
IIPKEOGD_01328 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IIPKEOGD_01329 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IIPKEOGD_01330 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
IIPKEOGD_01331 4.1e-84 uspA T Belongs to the universal stress protein A family
IIPKEOGD_01332 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
IIPKEOGD_01333 5.2e-173 ugpA U Binding-protein-dependent transport system inner membrane component
IIPKEOGD_01334 1.1e-150 ugpE G ABC transporter permease
IIPKEOGD_01335 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
IIPKEOGD_01336 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
IIPKEOGD_01337 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IIPKEOGD_01338 3.9e-179 XK27_06930 V domain protein
IIPKEOGD_01340 2.6e-124 V Transport permease protein
IIPKEOGD_01341 2.3e-156 V ABC transporter
IIPKEOGD_01342 4e-176 K LytTr DNA-binding domain
IIPKEOGD_01344 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IIPKEOGD_01345 1.6e-64 K helix_turn_helix, mercury resistance
IIPKEOGD_01346 3.5e-117 GM NAD(P)H-binding
IIPKEOGD_01347 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
IIPKEOGD_01348 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
IIPKEOGD_01349 1.7e-108
IIPKEOGD_01350 2.5e-223 pltK 2.7.13.3 T GHKL domain
IIPKEOGD_01351 1.6e-137 pltR K LytTr DNA-binding domain
IIPKEOGD_01352 4.5e-55
IIPKEOGD_01353 2.5e-59
IIPKEOGD_01354 1.9e-113 S CAAX protease self-immunity
IIPKEOGD_01355 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_01356 1e-90
IIPKEOGD_01357 2.5e-46
IIPKEOGD_01358 0.0 uvrA2 L ABC transporter
IIPKEOGD_01360 5.9e-52
IIPKEOGD_01361 3.5e-10
IIPKEOGD_01362 2.1e-180
IIPKEOGD_01363 1.9e-89 gtcA S Teichoic acid glycosylation protein
IIPKEOGD_01364 3.6e-58 S Protein of unknown function (DUF1516)
IIPKEOGD_01365 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
IIPKEOGD_01366 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IIPKEOGD_01367 1.2e-307 S Protein conserved in bacteria
IIPKEOGD_01368 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
IIPKEOGD_01369 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
IIPKEOGD_01370 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
IIPKEOGD_01371 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
IIPKEOGD_01372 0.0 yfbS P Sodium:sulfate symporter transmembrane region
IIPKEOGD_01373 6.5e-47
IIPKEOGD_01374 1.3e-57
IIPKEOGD_01375 2.3e-164
IIPKEOGD_01376 1.3e-72 K Transcriptional regulator
IIPKEOGD_01377 0.0 pepF2 E Oligopeptidase F
IIPKEOGD_01378 3.8e-173 D Alpha beta
IIPKEOGD_01379 1.2e-45 S Enterocin A Immunity
IIPKEOGD_01380 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
IIPKEOGD_01381 8.7e-125 skfE V ABC transporter
IIPKEOGD_01382 2.7e-132
IIPKEOGD_01383 3.7e-107 pncA Q Isochorismatase family
IIPKEOGD_01384 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IIPKEOGD_01385 0.0 yjcE P Sodium proton antiporter
IIPKEOGD_01386 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
IIPKEOGD_01387 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
IIPKEOGD_01388 1.1e-116 K Helix-turn-helix domain, rpiR family
IIPKEOGD_01389 2.3e-157 ccpB 5.1.1.1 K lacI family
IIPKEOGD_01390 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
IIPKEOGD_01391 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IIPKEOGD_01392 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
IIPKEOGD_01393 1.2e-97 drgA C Nitroreductase family
IIPKEOGD_01394 3.6e-168 S Polyphosphate kinase 2 (PPK2)
IIPKEOGD_01395 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_01396 3.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
IIPKEOGD_01397 0.0 glpQ 3.1.4.46 C phosphodiesterase
IIPKEOGD_01398 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IIPKEOGD_01399 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
IIPKEOGD_01400 3.9e-219 M domain protein
IIPKEOGD_01401 1.5e-41 M domain protein
IIPKEOGD_01402 0.0 ydgH S MMPL family
IIPKEOGD_01403 2.6e-112 S Protein of unknown function (DUF1211)
IIPKEOGD_01404 3.7e-34
IIPKEOGD_01405 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIPKEOGD_01406 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IIPKEOGD_01407 8.6e-98 J glyoxalase III activity
IIPKEOGD_01408 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPKEOGD_01409 5.9e-91 rmeB K transcriptional regulator, MerR family
IIPKEOGD_01410 2.1e-55 S Domain of unknown function (DU1801)
IIPKEOGD_01411 7.6e-166 corA P CorA-like Mg2+ transporter protein
IIPKEOGD_01412 4.6e-216 ysaA V RDD family
IIPKEOGD_01413 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
IIPKEOGD_01414 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IIPKEOGD_01415 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
IIPKEOGD_01416 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IIPKEOGD_01417 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
IIPKEOGD_01418 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IIPKEOGD_01419 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IIPKEOGD_01420 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
IIPKEOGD_01421 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IIPKEOGD_01422 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
IIPKEOGD_01423 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IIPKEOGD_01424 3.1e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IIPKEOGD_01425 3.1e-136 terC P membrane
IIPKEOGD_01426 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
IIPKEOGD_01427 5.7e-258 npr 1.11.1.1 C NADH oxidase
IIPKEOGD_01428 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
IIPKEOGD_01429 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IIPKEOGD_01430 3.1e-176 XK27_08835 S ABC transporter
IIPKEOGD_01431 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
IIPKEOGD_01432 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
IIPKEOGD_01433 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
IIPKEOGD_01434 5e-162 degV S Uncharacterised protein, DegV family COG1307
IIPKEOGD_01435 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
IIPKEOGD_01436 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IIPKEOGD_01437 6e-39
IIPKEOGD_01438 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
IIPKEOGD_01439 2e-106 3.2.2.20 K acetyltransferase
IIPKEOGD_01440 7.8e-296 S ABC transporter, ATP-binding protein
IIPKEOGD_01441 4.5e-121 S CAAX protease self-immunity
IIPKEOGD_01442 2.5e-114 V CAAX protease self-immunity
IIPKEOGD_01443 7.1e-121 yclH V ABC transporter
IIPKEOGD_01444 1.8e-185 yclI V MacB-like periplasmic core domain
IIPKEOGD_01445 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IIPKEOGD_01446 1.1e-106 tag 3.2.2.20 L glycosylase
IIPKEOGD_01447 0.0 ydgH S MMPL family
IIPKEOGD_01448 3.1e-104 K transcriptional regulator
IIPKEOGD_01449 2.7e-123 2.7.6.5 S RelA SpoT domain protein
IIPKEOGD_01450 1.3e-47
IIPKEOGD_01451 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
IIPKEOGD_01452 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IIPKEOGD_01453 2.1e-41
IIPKEOGD_01454 3.2e-55
IIPKEOGD_01455 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_01456 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
IIPKEOGD_01457 4.1e-49
IIPKEOGD_01458 7e-127 K Transcriptional regulatory protein, C terminal
IIPKEOGD_01459 9.8e-250 T PhoQ Sensor
IIPKEOGD_01460 3.3e-65 K helix_turn_helix, mercury resistance
IIPKEOGD_01461 1.1e-251 ydiC1 EGP Major facilitator Superfamily
IIPKEOGD_01462 1.4e-40
IIPKEOGD_01463 5.9e-38
IIPKEOGD_01464 5.1e-116
IIPKEOGD_01465 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
IIPKEOGD_01466 3.7e-120 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01467 1.8e-72 K Transcriptional regulator
IIPKEOGD_01468 3.5e-70
IIPKEOGD_01469 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
IIPKEOGD_01470 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IIPKEOGD_01471 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
IIPKEOGD_01472 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IIPKEOGD_01473 1.4e-144
IIPKEOGD_01474 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
IIPKEOGD_01475 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IIPKEOGD_01476 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IIPKEOGD_01477 3.5e-129 treR K UTRA
IIPKEOGD_01478 2.9e-42
IIPKEOGD_01479 7.3e-43 S Protein of unknown function (DUF2089)
IIPKEOGD_01480 4.3e-141 pnuC H nicotinamide mononucleotide transporter
IIPKEOGD_01481 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
IIPKEOGD_01482 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
IIPKEOGD_01483 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
IIPKEOGD_01484 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
IIPKEOGD_01485 3.5e-97 yieF S NADPH-dependent FMN reductase
IIPKEOGD_01486 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
IIPKEOGD_01487 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
IIPKEOGD_01488 7.7e-62
IIPKEOGD_01489 6.2e-94
IIPKEOGD_01490 1.2e-49
IIPKEOGD_01491 6.2e-57 trxA1 O Belongs to the thioredoxin family
IIPKEOGD_01492 2.1e-73
IIPKEOGD_01493 8.1e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IIPKEOGD_01494 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_01495 0.0 mtlR K Mga helix-turn-helix domain
IIPKEOGD_01496 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_01497 7.4e-277 pipD E Dipeptidase
IIPKEOGD_01498 4.8e-99 K Helix-turn-helix domain
IIPKEOGD_01499 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
IIPKEOGD_01500 2.2e-173 P Major Facilitator Superfamily
IIPKEOGD_01501 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IIPKEOGD_01502 4.7e-31 ygzD K Transcriptional
IIPKEOGD_01503 1e-69
IIPKEOGD_01504 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IIPKEOGD_01505 1.4e-158 dkgB S reductase
IIPKEOGD_01506 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
IIPKEOGD_01507 3.1e-101 S ABC transporter permease
IIPKEOGD_01508 2e-258 P ABC transporter
IIPKEOGD_01509 3.1e-116 P cobalt transport
IIPKEOGD_01510 1.6e-192 lys M Glycosyl hydrolases family 25
IIPKEOGD_01512 5.9e-21
IIPKEOGD_01513 1e-87
IIPKEOGD_01516 2.6e-15 S Domain of unknown function (DUF2479)
IIPKEOGD_01517 3.3e-96 S Domain of unknown function (DUF2479)
IIPKEOGD_01518 1.2e-172 E GDSL-like Lipase/Acylhydrolase family
IIPKEOGD_01519 1e-289 M Prophage endopeptidase tail
IIPKEOGD_01520 8.1e-134 S phage tail
IIPKEOGD_01521 0.0 D NLP P60 protein
IIPKEOGD_01523 4.3e-83 S Phage tail assembly chaperone protein, TAC
IIPKEOGD_01524 6.7e-96
IIPKEOGD_01525 4.1e-61
IIPKEOGD_01526 3.6e-94
IIPKEOGD_01527 1.7e-50
IIPKEOGD_01528 1.5e-56 S Phage gp6-like head-tail connector protein
IIPKEOGD_01529 1.5e-194 gpG
IIPKEOGD_01530 8.6e-71 S Domain of unknown function (DUF4355)
IIPKEOGD_01531 2.9e-168 S Phage Mu protein F like protein
IIPKEOGD_01532 7.6e-305 S Phage portal protein, SPP1 Gp6-like
IIPKEOGD_01533 8.7e-248 S Phage terminase, large subunit
IIPKEOGD_01535 2e-75 ps333 L Terminase small subunit
IIPKEOGD_01536 3.5e-11
IIPKEOGD_01538 2.2e-17
IIPKEOGD_01539 6.6e-31 rplV S ASCH
IIPKEOGD_01540 1.3e-79 K acetyltransferase
IIPKEOGD_01544 4.1e-14
IIPKEOGD_01545 2.4e-13 S YopX protein
IIPKEOGD_01547 4.9e-63 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IIPKEOGD_01548 2.2e-50
IIPKEOGD_01549 2.5e-161 L DnaD domain protein
IIPKEOGD_01550 1.4e-64
IIPKEOGD_01551 1.6e-54 S Bacteriophage Mu Gam like protein
IIPKEOGD_01553 2.8e-85
IIPKEOGD_01554 4.5e-54
IIPKEOGD_01556 1.3e-37 K Helix-turn-helix
IIPKEOGD_01557 4.5e-61 yvaO K Helix-turn-helix domain
IIPKEOGD_01558 3.3e-76 E IrrE N-terminal-like domain
IIPKEOGD_01559 8.4e-37
IIPKEOGD_01561 4.1e-13 S DNA/RNA non-specific endonuclease
IIPKEOGD_01565 7.3e-219 int L Belongs to the 'phage' integrase family
IIPKEOGD_01566 8.9e-30
IIPKEOGD_01569 3.6e-61
IIPKEOGD_01570 1.1e-35 S Phage gp6-like head-tail connector protein
IIPKEOGD_01571 7.2e-278 S Caudovirus prohead serine protease
IIPKEOGD_01572 1.1e-203 S Phage portal protein
IIPKEOGD_01574 0.0 terL S overlaps another CDS with the same product name
IIPKEOGD_01575 2.5e-83 terS L Phage terminase, small subunit
IIPKEOGD_01576 1.6e-67 L Phage-associated protein
IIPKEOGD_01577 4.6e-47 S head-tail joining protein
IIPKEOGD_01579 7e-74
IIPKEOGD_01580 7.9e-263 S Virulence-associated protein E
IIPKEOGD_01581 4.1e-147 L DNA replication protein
IIPKEOGD_01582 1.6e-29
IIPKEOGD_01586 6.4e-226 sip L Belongs to the 'phage' integrase family
IIPKEOGD_01587 2e-38
IIPKEOGD_01588 1.4e-43
IIPKEOGD_01589 7.3e-83 K MarR family
IIPKEOGD_01590 0.0 bztC D nuclear chromosome segregation
IIPKEOGD_01591 2.8e-167 M MucBP domain
IIPKEOGD_01592 1.5e-14
IIPKEOGD_01593 4.7e-16
IIPKEOGD_01594 1.6e-16
IIPKEOGD_01595 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
IIPKEOGD_01596 2e-61 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_01597 2e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_01598 0.0 macB3 V ABC transporter, ATP-binding protein
IIPKEOGD_01599 6.8e-24
IIPKEOGD_01600 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
IIPKEOGD_01601 3e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IIPKEOGD_01602 1.6e-140 S Belongs to the UPF0246 family
IIPKEOGD_01603 6e-76
IIPKEOGD_01604 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
IIPKEOGD_01605 7e-141
IIPKEOGD_01607 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
IIPKEOGD_01608 4.8e-40
IIPKEOGD_01609 7.8e-129 cbiO P ABC transporter
IIPKEOGD_01610 2.6e-149 P Cobalt transport protein
IIPKEOGD_01611 4.8e-182 nikMN P PDGLE domain
IIPKEOGD_01612 2.1e-120 K Crp-like helix-turn-helix domain
IIPKEOGD_01613 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
IIPKEOGD_01614 5.9e-124 larB S AIR carboxylase
IIPKEOGD_01615 8.5e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
IIPKEOGD_01616 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_01617 6.3e-151 larE S NAD synthase
IIPKEOGD_01618 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
IIPKEOGD_01619 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
IIPKEOGD_01620 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IIPKEOGD_01621 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
IIPKEOGD_01622 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
IIPKEOGD_01623 4.3e-135 S peptidase C26
IIPKEOGD_01624 9.8e-302 L HIRAN domain
IIPKEOGD_01625 3.4e-85 F NUDIX domain
IIPKEOGD_01626 2.6e-250 yifK E Amino acid permease
IIPKEOGD_01627 5.2e-122
IIPKEOGD_01628 3.3e-149 ydjP I Alpha/beta hydrolase family
IIPKEOGD_01629 0.0 pacL1 P P-type ATPase
IIPKEOGD_01630 2.9e-142 2.4.2.3 F Phosphorylase superfamily
IIPKEOGD_01631 1.6e-28 KT PspC domain
IIPKEOGD_01632 3.6e-111 S NADPH-dependent FMN reductase
IIPKEOGD_01633 1.2e-74 papX3 K Transcriptional regulator
IIPKEOGD_01634 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
IIPKEOGD_01635 5.8e-82 S Protein of unknown function (DUF3021)
IIPKEOGD_01636 4.7e-227 mdtG EGP Major facilitator Superfamily
IIPKEOGD_01637 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_01638 8.1e-216 yeaN P Transporter, major facilitator family protein
IIPKEOGD_01640 3.4e-160 S reductase
IIPKEOGD_01641 1.2e-165 1.1.1.65 C Aldo keto reductase
IIPKEOGD_01642 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
IIPKEOGD_01643 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IIPKEOGD_01644 7.8e-49
IIPKEOGD_01645 2.2e-258
IIPKEOGD_01646 4e-209 C Oxidoreductase
IIPKEOGD_01647 4.9e-151 cbiQ P cobalt transport
IIPKEOGD_01648 0.0 ykoD P ABC transporter, ATP-binding protein
IIPKEOGD_01649 2.5e-98 S UPF0397 protein
IIPKEOGD_01651 1.6e-129 K UbiC transcription regulator-associated domain protein
IIPKEOGD_01652 8.3e-54 K Transcriptional regulator PadR-like family
IIPKEOGD_01653 3e-134
IIPKEOGD_01654 5.8e-149
IIPKEOGD_01655 9.1e-89
IIPKEOGD_01656 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
IIPKEOGD_01657 2e-169 yjjC V ABC transporter
IIPKEOGD_01658 4.3e-297 M Exporter of polyketide antibiotics
IIPKEOGD_01659 1.1e-116 K Transcriptional regulator
IIPKEOGD_01660 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
IIPKEOGD_01661 9.5e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
IIPKEOGD_01663 1.9e-92 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01664 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IIPKEOGD_01665 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IIPKEOGD_01666 5.5e-101 dhaL 2.7.1.121 S Dak2
IIPKEOGD_01667 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
IIPKEOGD_01668 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_01669 1e-190 malR K Transcriptional regulator, LacI family
IIPKEOGD_01670 2e-180 yvdE K helix_turn _helix lactose operon repressor
IIPKEOGD_01671 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IIPKEOGD_01672 2.9e-148 yxeH S hydrolase
IIPKEOGD_01673 9e-264 ywfO S HD domain protein
IIPKEOGD_01674 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
IIPKEOGD_01675 3.8e-78 ywiB S Domain of unknown function (DUF1934)
IIPKEOGD_01676 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IIPKEOGD_01677 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IIPKEOGD_01678 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IIPKEOGD_01679 3.1e-229 tdcC E amino acid
IIPKEOGD_01680 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IIPKEOGD_01681 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IIPKEOGD_01682 6.4e-131 S YheO-like PAS domain
IIPKEOGD_01683 2.5e-26
IIPKEOGD_01684 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IIPKEOGD_01685 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IIPKEOGD_01686 7.8e-41 rpmE2 J Ribosomal protein L31
IIPKEOGD_01687 3.2e-214 J translation release factor activity
IIPKEOGD_01688 9.2e-127 srtA 3.4.22.70 M sortase family
IIPKEOGD_01689 1.7e-91 lemA S LemA family
IIPKEOGD_01690 4.6e-139 htpX O Belongs to the peptidase M48B family
IIPKEOGD_01691 2e-146
IIPKEOGD_01692 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IIPKEOGD_01693 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IIPKEOGD_01694 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IIPKEOGD_01695 9.3e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IIPKEOGD_01696 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
IIPKEOGD_01697 0.0 kup P Transport of potassium into the cell
IIPKEOGD_01698 2.9e-193 P ABC transporter, substratebinding protein
IIPKEOGD_01699 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
IIPKEOGD_01700 1.9e-133 P ATPases associated with a variety of cellular activities
IIPKEOGD_01701 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IIPKEOGD_01702 8.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IIPKEOGD_01703 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IIPKEOGD_01704 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IIPKEOGD_01705 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
IIPKEOGD_01706 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
IIPKEOGD_01707 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IIPKEOGD_01708 4.1e-84 S QueT transporter
IIPKEOGD_01709 6.2e-114 S (CBS) domain
IIPKEOGD_01710 4.2e-264 S Putative peptidoglycan binding domain
IIPKEOGD_01711 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IIPKEOGD_01712 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IIPKEOGD_01713 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IIPKEOGD_01714 4.3e-289 yabM S Polysaccharide biosynthesis protein
IIPKEOGD_01715 2.2e-42 yabO J S4 domain protein
IIPKEOGD_01717 1.1e-63 divIC D Septum formation initiator
IIPKEOGD_01718 3.1e-74 yabR J RNA binding
IIPKEOGD_01719 6.4e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IIPKEOGD_01720 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IIPKEOGD_01721 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IIPKEOGD_01722 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IIPKEOGD_01723 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIPKEOGD_01724 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IIPKEOGD_01725 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
IIPKEOGD_01726 0.0 cadA P P-type ATPase
IIPKEOGD_01728 1.8e-124 yyaQ S YjbR
IIPKEOGD_01729 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
IIPKEOGD_01730 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
IIPKEOGD_01731 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IIPKEOGD_01732 2.2e-199 frlB M SIS domain
IIPKEOGD_01733 3e-26 3.2.2.10 S Belongs to the LOG family
IIPKEOGD_01734 3.4e-253 nhaC C Na H antiporter NhaC
IIPKEOGD_01735 1.3e-249 cycA E Amino acid permease
IIPKEOGD_01736 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_01737 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_01738 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
IIPKEOGD_01739 7.7e-160 azoB GM NmrA-like family
IIPKEOGD_01740 5.4e-66 K Winged helix DNA-binding domain
IIPKEOGD_01741 7e-71 spx4 1.20.4.1 P ArsC family
IIPKEOGD_01742 1.7e-66 yeaO S Protein of unknown function, DUF488
IIPKEOGD_01743 4e-53
IIPKEOGD_01744 4.1e-214 mutY L A G-specific adenine glycosylase
IIPKEOGD_01745 1.9e-62
IIPKEOGD_01746 4.3e-86
IIPKEOGD_01747 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
IIPKEOGD_01748 5.9e-55
IIPKEOGD_01749 2.1e-14
IIPKEOGD_01750 1.1e-115 GM NmrA-like family
IIPKEOGD_01751 1.3e-81 elaA S GNAT family
IIPKEOGD_01752 5.9e-158 EG EamA-like transporter family
IIPKEOGD_01753 1.8e-119 S membrane
IIPKEOGD_01754 6.8e-111 S VIT family
IIPKEOGD_01755 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
IIPKEOGD_01756 0.0 copB 3.6.3.4 P P-type ATPase
IIPKEOGD_01757 4.7e-73 copR K Copper transport repressor CopY TcrY
IIPKEOGD_01758 7.4e-40
IIPKEOGD_01759 7.7e-73 S COG NOG18757 non supervised orthologous group
IIPKEOGD_01760 1.5e-248 lmrB EGP Major facilitator Superfamily
IIPKEOGD_01761 3.4e-25
IIPKEOGD_01762 4.2e-49
IIPKEOGD_01763 1.6e-64 ycgX S Protein of unknown function (DUF1398)
IIPKEOGD_01764 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
IIPKEOGD_01765 5.9e-214 mdtG EGP Major facilitator Superfamily
IIPKEOGD_01766 2.6e-180 D Alpha beta
IIPKEOGD_01767 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
IIPKEOGD_01768 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IIPKEOGD_01769 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
IIPKEOGD_01770 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IIPKEOGD_01771 8.4e-152 ywkB S Membrane transport protein
IIPKEOGD_01772 5.2e-164 yvgN C Aldo keto reductase
IIPKEOGD_01773 9.2e-133 thrE S Putative threonine/serine exporter
IIPKEOGD_01774 7.5e-77 S Threonine/Serine exporter, ThrE
IIPKEOGD_01775 2.3e-43 S Protein of unknown function (DUF1093)
IIPKEOGD_01776 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
IIPKEOGD_01777 2.7e-91 ymdB S Macro domain protein
IIPKEOGD_01778 1.2e-95 K transcriptional regulator
IIPKEOGD_01779 5.5e-50 yvlA
IIPKEOGD_01780 6e-161 ypuA S Protein of unknown function (DUF1002)
IIPKEOGD_01781 0.0
IIPKEOGD_01782 1.7e-121 S Bacterial protein of unknown function (DUF916)
IIPKEOGD_01783 3.6e-31
IIPKEOGD_01784 1.1e-138 Q Methyltransferase
IIPKEOGD_01785 8.5e-57 ybjQ S Belongs to the UPF0145 family
IIPKEOGD_01786 6.1e-211 EGP Major facilitator Superfamily
IIPKEOGD_01787 1.5e-98 K Helix-turn-helix domain
IIPKEOGD_01788 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IIPKEOGD_01789 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IIPKEOGD_01790 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
IIPKEOGD_01791 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPKEOGD_01792 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IIPKEOGD_01793 3.2e-46
IIPKEOGD_01794 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IIPKEOGD_01795 1.5e-135 fruR K DeoR C terminal sensor domain
IIPKEOGD_01796 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IIPKEOGD_01797 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
IIPKEOGD_01798 3.8e-251 cpdA S Calcineurin-like phosphoesterase
IIPKEOGD_01799 4.5e-261 cps4J S Polysaccharide biosynthesis protein
IIPKEOGD_01800 3e-176 cps4I M Glycosyltransferase like family 2
IIPKEOGD_01801 1.3e-232
IIPKEOGD_01802 6.5e-38 cps4G M Glycosyltransferase Family 4
IIPKEOGD_01803 2.7e-103 cps4G M Glycosyltransferase Family 4
IIPKEOGD_01804 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
IIPKEOGD_01805 7.4e-126 tuaA M Bacterial sugar transferase
IIPKEOGD_01806 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
IIPKEOGD_01807 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
IIPKEOGD_01808 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IIPKEOGD_01809 2.9e-126 epsB M biosynthesis protein
IIPKEOGD_01810 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IIPKEOGD_01811 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_01812 9.2e-270 glnPH2 P ABC transporter permease
IIPKEOGD_01813 4.3e-22
IIPKEOGD_01814 9.9e-73 S Iron-sulphur cluster biosynthesis
IIPKEOGD_01815 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
IIPKEOGD_01816 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
IIPKEOGD_01817 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IIPKEOGD_01818 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IIPKEOGD_01819 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IIPKEOGD_01820 1e-157 S Tetratricopeptide repeat
IIPKEOGD_01821 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIPKEOGD_01822 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IIPKEOGD_01823 7.2e-103 mdtG EGP Major Facilitator Superfamily
IIPKEOGD_01824 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IIPKEOGD_01825 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
IIPKEOGD_01826 7e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
IIPKEOGD_01827 0.0 comEC S Competence protein ComEC
IIPKEOGD_01828 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
IIPKEOGD_01829 6.8e-125 comEA L Competence protein ComEA
IIPKEOGD_01830 9.6e-197 ylbL T Belongs to the peptidase S16 family
IIPKEOGD_01831 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IIPKEOGD_01832 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IIPKEOGD_01833 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IIPKEOGD_01834 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IIPKEOGD_01835 8.2e-205 ftsW D Belongs to the SEDS family
IIPKEOGD_01836 1.2e-286
IIPKEOGD_01837 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
IIPKEOGD_01838 1.1e-161 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IIPKEOGD_01839 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IIPKEOGD_01840 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IIPKEOGD_01841 1.6e-180 galR K Transcriptional regulator
IIPKEOGD_01842 8e-76 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_01843 2.4e-22 fic D Fic/DOC family
IIPKEOGD_01844 1.9e-25 fic D Fic/DOC family
IIPKEOGD_01845 2.1e-38 fic D Fic/DOC family
IIPKEOGD_01846 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
IIPKEOGD_01847 2.5e-231 EGP Major facilitator Superfamily
IIPKEOGD_01848 2.1e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IIPKEOGD_01849 2.3e-229 mdtH P Sugar (and other) transporter
IIPKEOGD_01850 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
IIPKEOGD_01851 0.0 ubiB S ABC1 family
IIPKEOGD_01852 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_01853 3.9e-218 3.1.3.1 S associated with various cellular activities
IIPKEOGD_01854 1.4e-248 S Putative metallopeptidase domain
IIPKEOGD_01855 1.5e-49
IIPKEOGD_01856 7.7e-103 K Bacterial regulatory proteins, tetR family
IIPKEOGD_01857 4.6e-45
IIPKEOGD_01858 2.3e-99 S WxL domain surface cell wall-binding
IIPKEOGD_01859 1.5e-118 S WxL domain surface cell wall-binding
IIPKEOGD_01860 6.1e-164 S Cell surface protein
IIPKEOGD_01861 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
IIPKEOGD_01862 1.3e-262 nox C NADH oxidase
IIPKEOGD_01863 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IIPKEOGD_01864 0.0 pepO 3.4.24.71 O Peptidase family M13
IIPKEOGD_01865 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
IIPKEOGD_01866 1.6e-32 copZ P Heavy-metal-associated domain
IIPKEOGD_01867 6.6e-96 dps P Belongs to the Dps family
IIPKEOGD_01868 1.2e-18
IIPKEOGD_01869 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
IIPKEOGD_01870 1.5e-55 txlA O Thioredoxin-like domain
IIPKEOGD_01871 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_01872 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
IIPKEOGD_01873 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
IIPKEOGD_01874 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
IIPKEOGD_01875 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IIPKEOGD_01876 1.4e-181 yfeX P Peroxidase
IIPKEOGD_01877 1.3e-102 K transcriptional regulator
IIPKEOGD_01878 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
IIPKEOGD_01879 2.6e-65
IIPKEOGD_01881 1.6e-61
IIPKEOGD_01882 2.5e-53
IIPKEOGD_01883 2e-72 mltD CBM50 M PFAM NLP P60 protein
IIPKEOGD_01884 4.6e-279 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
IIPKEOGD_01885 1.8e-27
IIPKEOGD_01886 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IIPKEOGD_01887 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
IIPKEOGD_01888 1.3e-87 K Winged helix DNA-binding domain
IIPKEOGD_01889 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
IIPKEOGD_01890 5.1e-129 S WxL domain surface cell wall-binding
IIPKEOGD_01891 2e-56 S Bacterial protein of unknown function (DUF916)
IIPKEOGD_01892 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IIPKEOGD_01893 6.8e-127 yliE T EAL domain
IIPKEOGD_01894 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIPKEOGD_01895 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IIPKEOGD_01896 2e-80
IIPKEOGD_01897 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IIPKEOGD_01898 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIPKEOGD_01899 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIPKEOGD_01900 4.9e-22
IIPKEOGD_01901 2.9e-70
IIPKEOGD_01902 1.2e-163 K LysR substrate binding domain
IIPKEOGD_01903 2.4e-243 P Sodium:sulfate symporter transmembrane region
IIPKEOGD_01904 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
IIPKEOGD_01905 1.5e-264 S response to antibiotic
IIPKEOGD_01906 2.8e-134 S zinc-ribbon domain
IIPKEOGD_01908 3.2e-37
IIPKEOGD_01909 8.3e-108 aroD S Alpha/beta hydrolase family
IIPKEOGD_01910 1.7e-15 aroD S Alpha/beta hydrolase family
IIPKEOGD_01911 2.6e-176 S Phosphotransferase system, EIIC
IIPKEOGD_01912 2.5e-269 I acetylesterase activity
IIPKEOGD_01913 1.6e-51 sdrF M Collagen binding domain
IIPKEOGD_01914 1.1e-159 yicL EG EamA-like transporter family
IIPKEOGD_01915 1.3e-128 E lipolytic protein G-D-S-L family
IIPKEOGD_01916 1.7e-176 4.1.1.52 S Amidohydrolase
IIPKEOGD_01917 2.5e-112 K Transcriptional regulator C-terminal region
IIPKEOGD_01918 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
IIPKEOGD_01919 4.2e-161 ypbG 2.7.1.2 GK ROK family
IIPKEOGD_01920 0.0 ybfG M peptidoglycan-binding domain-containing protein
IIPKEOGD_01921 5.6e-89
IIPKEOGD_01922 7.6e-132 lmrA 3.6.3.44 V ABC transporter
IIPKEOGD_01923 2.4e-187 lmrA 3.6.3.44 V ABC transporter
IIPKEOGD_01924 5e-93 rmaB K Transcriptional regulator, MarR family
IIPKEOGD_01925 7.1e-159 ccpB 5.1.1.1 K lacI family
IIPKEOGD_01926 3e-121 yceE S haloacid dehalogenase-like hydrolase
IIPKEOGD_01927 1.3e-119 drgA C Nitroreductase family
IIPKEOGD_01928 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
IIPKEOGD_01929 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
IIPKEOGD_01930 5.6e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
IIPKEOGD_01931 1.5e-167 XK27_00670 S ABC transporter
IIPKEOGD_01932 1e-260
IIPKEOGD_01933 7.3e-62
IIPKEOGD_01934 2.5e-189 S Cell surface protein
IIPKEOGD_01935 2.3e-91 S WxL domain surface cell wall-binding
IIPKEOGD_01936 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
IIPKEOGD_01937 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
IIPKEOGD_01938 3.3e-124 livF E ABC transporter
IIPKEOGD_01939 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
IIPKEOGD_01940 5.3e-141 livM E Branched-chain amino acid transport system / permease component
IIPKEOGD_01941 2.1e-149 livH U Branched-chain amino acid transport system / permease component
IIPKEOGD_01942 5.4e-212 livJ E Receptor family ligand binding region
IIPKEOGD_01944 7e-33
IIPKEOGD_01945 1.6e-174 corA P CorA-like Mg2+ transporter protein
IIPKEOGD_01946 1.9e-62 S Protein of unknown function (DUF3397)
IIPKEOGD_01947 1.9e-77 mraZ K Belongs to the MraZ family
IIPKEOGD_01948 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IIPKEOGD_01949 7.5e-54 ftsL D Cell division protein FtsL
IIPKEOGD_01950 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IIPKEOGD_01951 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IIPKEOGD_01952 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IIPKEOGD_01953 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IIPKEOGD_01954 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IIPKEOGD_01955 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IIPKEOGD_01956 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IIPKEOGD_01957 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IIPKEOGD_01958 1.2e-36 yggT S YGGT family
IIPKEOGD_01959 3.4e-146 ylmH S S4 domain protein
IIPKEOGD_01960 1.2e-86 divIVA D DivIVA domain protein
IIPKEOGD_01961 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IIPKEOGD_01962 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IIPKEOGD_01963 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IIPKEOGD_01964 4.6e-28
IIPKEOGD_01965 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IIPKEOGD_01966 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
IIPKEOGD_01967 4.9e-57 XK27_04120 S Putative amino acid metabolism
IIPKEOGD_01968 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IIPKEOGD_01969 1.3e-241 ktrB P Potassium uptake protein
IIPKEOGD_01970 2.6e-115 ktrA P domain protein
IIPKEOGD_01971 2.3e-120 N WxL domain surface cell wall-binding
IIPKEOGD_01972 1.9e-192 S Bacterial protein of unknown function (DUF916)
IIPKEOGD_01973 1.6e-266 N domain, Protein
IIPKEOGD_01974 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
IIPKEOGD_01975 1.6e-120 S Repeat protein
IIPKEOGD_01976 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IIPKEOGD_01977 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIPKEOGD_01978 2.6e-107 mltD CBM50 M NlpC P60 family protein
IIPKEOGD_01979 1.7e-28
IIPKEOGD_01980 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IIPKEOGD_01981 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IIPKEOGD_01982 3.1e-33 ykzG S Belongs to the UPF0356 family
IIPKEOGD_01983 1.6e-85
IIPKEOGD_01984 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IIPKEOGD_01985 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
IIPKEOGD_01986 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
IIPKEOGD_01987 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
IIPKEOGD_01988 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
IIPKEOGD_01989 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
IIPKEOGD_01990 3.3e-46 yktA S Belongs to the UPF0223 family
IIPKEOGD_01991 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
IIPKEOGD_01992 0.0 typA T GTP-binding protein TypA
IIPKEOGD_01993 1.1e-172
IIPKEOGD_01994 2e-77 merR K MerR family regulatory protein
IIPKEOGD_01995 9e-156 1.6.5.2 GM NmrA-like family
IIPKEOGD_01996 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
IIPKEOGD_01997 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
IIPKEOGD_01998 1.4e-08
IIPKEOGD_01999 1.1e-77 S NADPH-dependent FMN reductase
IIPKEOGD_02000 7.9e-238 S module of peptide synthetase
IIPKEOGD_02001 8.4e-105
IIPKEOGD_02002 1.3e-87 perR P Belongs to the Fur family
IIPKEOGD_02003 7.1e-59 S Enterocin A Immunity
IIPKEOGD_02004 5.4e-36 S Phospholipase_D-nuclease N-terminal
IIPKEOGD_02005 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IIPKEOGD_02006 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
IIPKEOGD_02007 3.8e-104 J Acetyltransferase (GNAT) domain
IIPKEOGD_02008 5.1e-64 lrgA S LrgA family
IIPKEOGD_02009 7.3e-127 lrgB M LrgB-like family
IIPKEOGD_02010 7.1e-145 DegV S EDD domain protein, DegV family
IIPKEOGD_02011 4.1e-25
IIPKEOGD_02012 5e-117 yugP S Putative neutral zinc metallopeptidase
IIPKEOGD_02013 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
IIPKEOGD_02014 6.9e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
IIPKEOGD_02015 4.2e-183 D Alpha beta
IIPKEOGD_02016 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IIPKEOGD_02017 1.9e-258 gor 1.8.1.7 C Glutathione reductase
IIPKEOGD_02018 9.8e-55 S Enterocin A Immunity
IIPKEOGD_02019 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IIPKEOGD_02020 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IIPKEOGD_02021 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIPKEOGD_02022 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
IIPKEOGD_02023 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IIPKEOGD_02025 2.1e-82
IIPKEOGD_02026 2.3e-257 yhdG E C-terminus of AA_permease
IIPKEOGD_02028 0.0 kup P Transport of potassium into the cell
IIPKEOGD_02029 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IIPKEOGD_02030 5.3e-179 K AI-2E family transporter
IIPKEOGD_02031 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
IIPKEOGD_02032 5.8e-59 qacC P Small Multidrug Resistance protein
IIPKEOGD_02033 1.1e-44 qacH U Small Multidrug Resistance protein
IIPKEOGD_02034 3e-116 hly S protein, hemolysin III
IIPKEOGD_02035 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_02036 2.7e-160 czcD P cation diffusion facilitator family transporter
IIPKEOGD_02037 2.6e-19
IIPKEOGD_02038 6.5e-96 tag 3.2.2.20 L glycosylase
IIPKEOGD_02039 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
IIPKEOGD_02040 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
IIPKEOGD_02041 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IIPKEOGD_02042 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
IIPKEOGD_02043 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
IIPKEOGD_02044 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IIPKEOGD_02045 4.7e-83 cvpA S Colicin V production protein
IIPKEOGD_02046 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
IIPKEOGD_02047 1.3e-249 EGP Major facilitator Superfamily
IIPKEOGD_02049 7e-40
IIPKEOGD_02050 6.6e-113 zmp3 O Zinc-dependent metalloprotease
IIPKEOGD_02051 2.8e-82 gtrA S GtrA-like protein
IIPKEOGD_02052 6.1e-122 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_02053 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
IIPKEOGD_02054 6.8e-72 T Belongs to the universal stress protein A family
IIPKEOGD_02055 1.1e-46
IIPKEOGD_02056 1.9e-116 S SNARE associated Golgi protein
IIPKEOGD_02057 2e-49 K Transcriptional regulator, ArsR family
IIPKEOGD_02058 1.2e-95 cadD P Cadmium resistance transporter
IIPKEOGD_02059 0.0 yhcA V ABC transporter, ATP-binding protein
IIPKEOGD_02060 2.3e-24 P Concanavalin A-like lectin/glucanases superfamily
IIPKEOGD_02062 7.4e-64
IIPKEOGD_02063 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
IIPKEOGD_02064 3.2e-55
IIPKEOGD_02065 5.3e-150 dicA K Helix-turn-helix domain
IIPKEOGD_02066 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IIPKEOGD_02067 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_02068 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02069 9.2e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02070 5.3e-184 1.1.1.219 GM Male sterility protein
IIPKEOGD_02071 5.1e-75 K helix_turn_helix, mercury resistance
IIPKEOGD_02072 2.3e-65 M LysM domain
IIPKEOGD_02073 6.7e-87 M Lysin motif
IIPKEOGD_02074 1.8e-107 S SdpI/YhfL protein family
IIPKEOGD_02075 1.8e-54 nudA S ASCH
IIPKEOGD_02076 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
IIPKEOGD_02077 4.2e-92
IIPKEOGD_02078 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
IIPKEOGD_02079 3.3e-219 T diguanylate cyclase
IIPKEOGD_02080 1.2e-73 S Psort location Cytoplasmic, score
IIPKEOGD_02081 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
IIPKEOGD_02082 8.6e-218 ykiI
IIPKEOGD_02083 0.0 V ABC transporter
IIPKEOGD_02084 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
IIPKEOGD_02086 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
IIPKEOGD_02087 7.7e-163 IQ KR domain
IIPKEOGD_02089 7.4e-71
IIPKEOGD_02090 4.3e-144 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_02091 9.6e-267 yjeM E Amino Acid
IIPKEOGD_02092 1.1e-65 lysM M LysM domain
IIPKEOGD_02093 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
IIPKEOGD_02094 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
IIPKEOGD_02095 0.0 ctpA 3.6.3.54 P P-type ATPase
IIPKEOGD_02096 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IIPKEOGD_02097 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IIPKEOGD_02098 2.1e-244 dinF V MatE
IIPKEOGD_02099 1.9e-31
IIPKEOGD_02101 1.5e-77 elaA S Acetyltransferase (GNAT) domain
IIPKEOGD_02102 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IIPKEOGD_02103 1.4e-81
IIPKEOGD_02104 0.0 yhcA V MacB-like periplasmic core domain
IIPKEOGD_02105 1.1e-105
IIPKEOGD_02106 0.0 K PRD domain
IIPKEOGD_02107 2.4e-62 S Domain of unknown function (DUF3284)
IIPKEOGD_02108 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IIPKEOGD_02109 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_02110 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02111 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02112 9.5e-209 EGP Major facilitator Superfamily
IIPKEOGD_02113 1.5e-112 M ErfK YbiS YcfS YnhG
IIPKEOGD_02114 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IIPKEOGD_02115 2.4e-283 ydfD K Alanine-glyoxylate amino-transferase
IIPKEOGD_02116 1.4e-102 argO S LysE type translocator
IIPKEOGD_02117 7.1e-214 arcT 2.6.1.1 E Aminotransferase
IIPKEOGD_02118 4.4e-77 argR K Regulates arginine biosynthesis genes
IIPKEOGD_02119 2.9e-12
IIPKEOGD_02120 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IIPKEOGD_02121 1e-54 yheA S Belongs to the UPF0342 family
IIPKEOGD_02122 5.7e-233 yhaO L Ser Thr phosphatase family protein
IIPKEOGD_02123 0.0 L AAA domain
IIPKEOGD_02124 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
IIPKEOGD_02125 2.1e-213
IIPKEOGD_02126 3.1e-181 3.4.21.102 M Peptidase family S41
IIPKEOGD_02127 7.6e-177 K LysR substrate binding domain
IIPKEOGD_02128 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
IIPKEOGD_02129 0.0 1.3.5.4 C FAD binding domain
IIPKEOGD_02130 1.7e-99
IIPKEOGD_02131 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
IIPKEOGD_02132 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
IIPKEOGD_02133 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIPKEOGD_02134 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IIPKEOGD_02135 1.7e-19 S NUDIX domain
IIPKEOGD_02136 0.0 S membrane
IIPKEOGD_02137 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IIPKEOGD_02138 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IIPKEOGD_02139 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IIPKEOGD_02140 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IIPKEOGD_02141 9.3e-106 GBS0088 S Nucleotidyltransferase
IIPKEOGD_02142 5.5e-106
IIPKEOGD_02143 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IIPKEOGD_02144 4.7e-74 K Bacterial regulatory proteins, tetR family
IIPKEOGD_02145 4.4e-35 yyaN K MerR HTH family regulatory protein
IIPKEOGD_02146 1.7e-120 azlC E branched-chain amino acid
IIPKEOGD_02147 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
IIPKEOGD_02148 0.0 asnB 6.3.5.4 E Asparagine synthase
IIPKEOGD_02149 1e-218 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
IIPKEOGD_02150 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IIPKEOGD_02151 1e-254 xylP2 G symporter
IIPKEOGD_02152 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
IIPKEOGD_02153 5.6e-49
IIPKEOGD_02154 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IIPKEOGD_02155 2e-91 3.2.2.20 K FR47-like protein
IIPKEOGD_02156 3.4e-127 yibF S overlaps another CDS with the same product name
IIPKEOGD_02157 1.4e-218 yibE S overlaps another CDS with the same product name
IIPKEOGD_02158 3.9e-179
IIPKEOGD_02159 5.6e-138 S NADPH-dependent FMN reductase
IIPKEOGD_02160 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_02161 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
IIPKEOGD_02162 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IIPKEOGD_02163 4.1e-32 L leucine-zipper of insertion element IS481
IIPKEOGD_02164 8.5e-41
IIPKEOGD_02165 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IIPKEOGD_02166 6.7e-278 pipD E Dipeptidase
IIPKEOGD_02167 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
IIPKEOGD_02168 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IIPKEOGD_02169 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IIPKEOGD_02170 2.3e-81 rmaD K Transcriptional regulator
IIPKEOGD_02172 1.3e-210 1.3.5.4 C FMN_bind
IIPKEOGD_02173 1.2e-97 1.3.5.4 C FMN_bind
IIPKEOGD_02174 2.8e-171 K Transcriptional regulator
IIPKEOGD_02175 5.2e-41 K Helix-turn-helix domain
IIPKEOGD_02176 7.2e-47 K Helix-turn-helix domain
IIPKEOGD_02177 2.3e-139 K sequence-specific DNA binding
IIPKEOGD_02178 6.5e-87 S AAA domain
IIPKEOGD_02180 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IIPKEOGD_02181 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
IIPKEOGD_02182 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
IIPKEOGD_02183 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
IIPKEOGD_02184 2.7e-171 L Belongs to the 'phage' integrase family
IIPKEOGD_02185 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
IIPKEOGD_02186 1.7e-151 hsdM 2.1.1.72 V type I restriction-modification system
IIPKEOGD_02187 3.7e-95 hsdM 2.1.1.72 V type I restriction-modification system
IIPKEOGD_02188 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IIPKEOGD_02189 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
IIPKEOGD_02190 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
IIPKEOGD_02191 7.4e-102 M Protein of unknown function (DUF3737)
IIPKEOGD_02192 1.2e-194 C Aldo/keto reductase family
IIPKEOGD_02194 0.0 mdlB V ABC transporter
IIPKEOGD_02195 0.0 mdlA V ABC transporter
IIPKEOGD_02196 1.3e-246 EGP Major facilitator Superfamily
IIPKEOGD_02201 1e-197 yhgE V domain protein
IIPKEOGD_02202 1.5e-95 K Transcriptional regulator (TetR family)
IIPKEOGD_02203 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
IIPKEOGD_02204 1.7e-139 endA F DNA RNA non-specific endonuclease
IIPKEOGD_02205 6.3e-99 speG J Acetyltransferase (GNAT) domain
IIPKEOGD_02206 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
IIPKEOGD_02207 1.1e-223 S CAAX protease self-immunity
IIPKEOGD_02208 1.2e-307 ybiT S ABC transporter, ATP-binding protein
IIPKEOGD_02209 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
IIPKEOGD_02210 0.0 S Predicted membrane protein (DUF2207)
IIPKEOGD_02211 0.0 uvrA3 L excinuclease ABC
IIPKEOGD_02212 3.1e-207 EGP Major facilitator Superfamily
IIPKEOGD_02213 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
IIPKEOGD_02214 2e-233 yxiO S Vacuole effluxer Atg22 like
IIPKEOGD_02215 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
IIPKEOGD_02216 1.1e-158 I alpha/beta hydrolase fold
IIPKEOGD_02217 7e-130 treR K UTRA
IIPKEOGD_02218 1.2e-234
IIPKEOGD_02219 5.6e-39 S Cytochrome B5
IIPKEOGD_02220 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IIPKEOGD_02221 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
IIPKEOGD_02222 1.8e-159 lys M Glycosyl hydrolases family 25
IIPKEOGD_02223 4.7e-20
IIPKEOGD_02224 2.9e-71
IIPKEOGD_02227 2.3e-88
IIPKEOGD_02228 2.7e-139 S Phage minor structural protein
IIPKEOGD_02229 0.0 S Phage tail protein
IIPKEOGD_02230 0.0 D NLP P60 protein
IIPKEOGD_02231 6.6e-24
IIPKEOGD_02232 1.8e-57 S Phage tail assembly chaperone proteins, TAC
IIPKEOGD_02233 3e-103 S Phage tail tube protein
IIPKEOGD_02234 3.5e-56 S Protein of unknown function (DUF806)
IIPKEOGD_02235 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
IIPKEOGD_02236 1.7e-57 S Phage head-tail joining protein
IIPKEOGD_02237 6.2e-49 S Phage gp6-like head-tail connector protein
IIPKEOGD_02238 7.5e-201 S Phage capsid family
IIPKEOGD_02239 6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
IIPKEOGD_02240 5.2e-223 S Phage portal protein
IIPKEOGD_02241 2.1e-25 S Protein of unknown function (DUF1056)
IIPKEOGD_02242 0.0 S Phage Terminase
IIPKEOGD_02243 3.6e-79 L Phage terminase, small subunit
IIPKEOGD_02245 6.1e-88 L HNH nucleases
IIPKEOGD_02246 8.2e-65 S Transcriptional regulator, RinA family
IIPKEOGD_02247 1.4e-15
IIPKEOGD_02248 1.4e-55
IIPKEOGD_02249 1.2e-09 S YopX protein
IIPKEOGD_02251 7e-96 2.1.1.37 L C-5 cytosine-specific DNA methylase
IIPKEOGD_02254 3.7e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
IIPKEOGD_02256 1.4e-131 pi346 L IstB-like ATP binding protein
IIPKEOGD_02257 3.9e-130 S Putative HNHc nuclease
IIPKEOGD_02258 1.2e-91 S Protein of unknown function (DUF669)
IIPKEOGD_02259 8.1e-117 S AAA domain
IIPKEOGD_02260 2.8e-146 S Protein of unknown function (DUF1351)
IIPKEOGD_02262 6.3e-18
IIPKEOGD_02269 7.2e-63 S DNA binding
IIPKEOGD_02272 8.8e-20
IIPKEOGD_02273 4.5e-78 K Peptidase S24-like
IIPKEOGD_02280 3.1e-63 L Belongs to the 'phage' integrase family
IIPKEOGD_02281 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IIPKEOGD_02282 2.3e-270 G Major Facilitator
IIPKEOGD_02283 1.1e-173 K Transcriptional regulator, LacI family
IIPKEOGD_02284 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
IIPKEOGD_02285 3.8e-159 licT K CAT RNA binding domain
IIPKEOGD_02286 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
IIPKEOGD_02287 5.5e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02288 3.4e-171 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02289 1.3e-154 licT K CAT RNA binding domain
IIPKEOGD_02290 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IIPKEOGD_02291 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02292 1.1e-211 S Bacterial protein of unknown function (DUF871)
IIPKEOGD_02293 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IIPKEOGD_02294 4.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IIPKEOGD_02295 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02296 1.2e-134 K UTRA domain
IIPKEOGD_02297 3.4e-154 estA S Putative esterase
IIPKEOGD_02298 1e-63
IIPKEOGD_02299 1.8e-210 ydiN G Major Facilitator Superfamily
IIPKEOGD_02300 3.4e-163 K Transcriptional regulator, LysR family
IIPKEOGD_02301 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IIPKEOGD_02302 2.7e-214 ydiM G Transporter
IIPKEOGD_02303 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
IIPKEOGD_02304 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IIPKEOGD_02305 0.0 1.3.5.4 C FAD binding domain
IIPKEOGD_02306 5.2e-65 S pyridoxamine 5-phosphate
IIPKEOGD_02307 3.1e-192 C Aldo keto reductase family protein
IIPKEOGD_02308 1.1e-173 galR K Transcriptional regulator
IIPKEOGD_02309 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IIPKEOGD_02310 0.0 lacS G Transporter
IIPKEOGD_02311 9.2e-131 znuB U ABC 3 transport family
IIPKEOGD_02312 9.8e-129 fhuC 3.6.3.35 P ABC transporter
IIPKEOGD_02313 1.3e-181 S Prolyl oligopeptidase family
IIPKEOGD_02314 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IIPKEOGD_02315 3.2e-37 veg S Biofilm formation stimulator VEG
IIPKEOGD_02316 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IIPKEOGD_02317 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IIPKEOGD_02318 1.5e-146 tatD L hydrolase, TatD family
IIPKEOGD_02320 1.3e-83 mutR K sequence-specific DNA binding
IIPKEOGD_02321 2e-214 bcr1 EGP Major facilitator Superfamily
IIPKEOGD_02322 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IIPKEOGD_02323 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
IIPKEOGD_02324 2e-160 yunF F Protein of unknown function DUF72
IIPKEOGD_02325 2.5e-132 cobB K SIR2 family
IIPKEOGD_02326 2.7e-177
IIPKEOGD_02327 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
IIPKEOGD_02328 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
IIPKEOGD_02329 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IIPKEOGD_02330 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IIPKEOGD_02331 4.8e-34
IIPKEOGD_02332 4.9e-75 S Domain of unknown function (DUF3284)
IIPKEOGD_02333 3.9e-24
IIPKEOGD_02334 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02335 9e-130 K UbiC transcription regulator-associated domain protein
IIPKEOGD_02336 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IIPKEOGD_02337 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
IIPKEOGD_02338 0.0 helD 3.6.4.12 L DNA helicase
IIPKEOGD_02339 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
IIPKEOGD_02340 9.6e-113 S CAAX protease self-immunity
IIPKEOGD_02341 1.2e-110 V CAAX protease self-immunity
IIPKEOGD_02342 7.4e-118 ypbD S CAAX protease self-immunity
IIPKEOGD_02343 1.4e-108 S CAAX protease self-immunity
IIPKEOGD_02344 7.5e-242 mesE M Transport protein ComB
IIPKEOGD_02345 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IIPKEOGD_02346 5.5e-13
IIPKEOGD_02347 2.4e-22 plnF
IIPKEOGD_02348 2.2e-129 S CAAX protease self-immunity
IIPKEOGD_02349 1.3e-189 ynfM EGP Major facilitator Superfamily
IIPKEOGD_02350 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IIPKEOGD_02351 4.1e-270 lmrB EGP Major facilitator Superfamily
IIPKEOGD_02352 2e-75 S Domain of unknown function (DUF4811)
IIPKEOGD_02353 1.8e-101 rimL J Acetyltransferase (GNAT) domain
IIPKEOGD_02354 9.3e-173 S Conserved hypothetical protein 698
IIPKEOGD_02355 4.8e-151 rlrG K Transcriptional regulator
IIPKEOGD_02356 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
IIPKEOGD_02357 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
IIPKEOGD_02359 1.8e-46 lytE M LysM domain
IIPKEOGD_02360 1.2e-91 ogt 2.1.1.63 L Methyltransferase
IIPKEOGD_02361 7.5e-166 natA S ABC transporter, ATP-binding protein
IIPKEOGD_02362 1.4e-210 natB CP ABC-2 family transporter protein
IIPKEOGD_02363 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPKEOGD_02364 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
IIPKEOGD_02365 3.2e-76 yphH S Cupin domain
IIPKEOGD_02366 2.9e-78 K transcriptional regulator, MerR family
IIPKEOGD_02367 1.4e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IIPKEOGD_02368 0.0 ylbB V ABC transporter permease
IIPKEOGD_02369 7.5e-121 macB V ABC transporter, ATP-binding protein
IIPKEOGD_02371 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IIPKEOGD_02372 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
IIPKEOGD_02373 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IIPKEOGD_02375 3.8e-84
IIPKEOGD_02376 2.8e-85 yvbK 3.1.3.25 K GNAT family
IIPKEOGD_02377 3.2e-37
IIPKEOGD_02378 8.2e-48
IIPKEOGD_02379 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
IIPKEOGD_02380 3.8e-63 S Domain of unknown function (DUF4440)
IIPKEOGD_02381 6.9e-156 K LysR substrate binding domain
IIPKEOGD_02382 1.9e-104 GM NAD(P)H-binding
IIPKEOGD_02383 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IIPKEOGD_02384 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
IIPKEOGD_02385 1.3e-34
IIPKEOGD_02386 6.1e-76 T Belongs to the universal stress protein A family
IIPKEOGD_02387 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
IIPKEOGD_02388 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IIPKEOGD_02389 2.1e-31
IIPKEOGD_02390 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
IIPKEOGD_02391 4.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IIPKEOGD_02392 0.0 rafA 3.2.1.22 G alpha-galactosidase
IIPKEOGD_02393 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IIPKEOGD_02394 1.5e-304 scrB 3.2.1.26 GH32 G invertase
IIPKEOGD_02395 5.9e-172 scrR K Transcriptional regulator, LacI family
IIPKEOGD_02396 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IIPKEOGD_02397 1.4e-164 3.5.1.10 C nadph quinone reductase
IIPKEOGD_02398 1.1e-217 nhaC C Na H antiporter NhaC
IIPKEOGD_02399 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IIPKEOGD_02400 2.9e-128 mleR K LysR substrate binding domain
IIPKEOGD_02401 5e-27 mleR K LysR substrate binding domain
IIPKEOGD_02402 0.0 3.6.4.13 M domain protein
IIPKEOGD_02404 2.1e-157 hipB K Helix-turn-helix
IIPKEOGD_02405 0.0 oppA E ABC transporter, substratebinding protein
IIPKEOGD_02406 1.8e-309 oppA E ABC transporter, substratebinding protein
IIPKEOGD_02407 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
IIPKEOGD_02408 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IIPKEOGD_02409 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IIPKEOGD_02410 3e-113 pgm1 G phosphoglycerate mutase
IIPKEOGD_02411 7.2e-178 yghZ C Aldo keto reductase family protein
IIPKEOGD_02412 4.9e-34
IIPKEOGD_02413 1.3e-60 S Domain of unknown function (DU1801)
IIPKEOGD_02414 2.9e-162 FbpA K Domain of unknown function (DUF814)
IIPKEOGD_02415 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIPKEOGD_02417 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIPKEOGD_02418 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IIPKEOGD_02419 2.6e-212 S ATPases associated with a variety of cellular activities
IIPKEOGD_02420 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IIPKEOGD_02421 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
IIPKEOGD_02422 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_02423 3.7e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
IIPKEOGD_02424 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
IIPKEOGD_02425 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IIPKEOGD_02426 1.1e-147 cof S haloacid dehalogenase-like hydrolase
IIPKEOGD_02427 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
IIPKEOGD_02428 9.4e-77
IIPKEOGD_02429 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IIPKEOGD_02430 1.4e-116 ybbL S ABC transporter, ATP-binding protein
IIPKEOGD_02431 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
IIPKEOGD_02432 2.6e-205 S DUF218 domain
IIPKEOGD_02433 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
IIPKEOGD_02434 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IIPKEOGD_02435 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
IIPKEOGD_02436 2.1e-126 S Putative adhesin
IIPKEOGD_02437 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
IIPKEOGD_02438 9.8e-52 K Transcriptional regulator
IIPKEOGD_02439 5.8e-79 KT response to antibiotic
IIPKEOGD_02440 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IIPKEOGD_02441 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_02442 8.1e-123 tcyB E ABC transporter
IIPKEOGD_02443 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
IIPKEOGD_02444 1.9e-236 EK Aminotransferase, class I
IIPKEOGD_02445 2.1e-168 K LysR substrate binding domain
IIPKEOGD_02446 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_02447 2.9e-253 S Bacterial membrane protein YfhO
IIPKEOGD_02448 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
IIPKEOGD_02449 3.6e-11
IIPKEOGD_02450 9e-13 ytgB S Transglycosylase associated protein
IIPKEOGD_02451 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
IIPKEOGD_02452 4.9e-78 yneH 1.20.4.1 K ArsC family
IIPKEOGD_02453 7.4e-135 K LytTr DNA-binding domain
IIPKEOGD_02454 8.7e-160 2.7.13.3 T GHKL domain
IIPKEOGD_02455 1.8e-12
IIPKEOGD_02456 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
IIPKEOGD_02457 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
IIPKEOGD_02459 5.1e-57 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IIPKEOGD_02460 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IIPKEOGD_02461 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPKEOGD_02462 8.7e-72 K Transcriptional regulator
IIPKEOGD_02463 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IIPKEOGD_02464 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IIPKEOGD_02465 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
IIPKEOGD_02466 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
IIPKEOGD_02467 1.1e-86 gutM K Glucitol operon activator protein (GutM)
IIPKEOGD_02468 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
IIPKEOGD_02469 3.8e-145 IQ NAD dependent epimerase/dehydratase family
IIPKEOGD_02470 2.7e-160 rbsU U ribose uptake protein RbsU
IIPKEOGD_02471 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
IIPKEOGD_02472 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IIPKEOGD_02473 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
IIPKEOGD_02475 3e-08
IIPKEOGD_02476 9.1e-50
IIPKEOGD_02477 2.4e-114 K UTRA
IIPKEOGD_02478 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IIPKEOGD_02479 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02480 4.1e-65
IIPKEOGD_02481 6.4e-63 S Protein of unknown function (DUF1093)
IIPKEOGD_02482 4.3e-207 S Membrane
IIPKEOGD_02483 1.1e-43 S Protein of unknown function (DUF3781)
IIPKEOGD_02484 1e-107 ydeA S intracellular protease amidase
IIPKEOGD_02485 2.2e-41 K HxlR-like helix-turn-helix
IIPKEOGD_02486 3.3e-66
IIPKEOGD_02487 1e-64 V ABC transporter
IIPKEOGD_02488 2.3e-51 K Helix-turn-helix domain
IIPKEOGD_02489 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
IIPKEOGD_02490 1.4e-46 K Helix-turn-helix domain
IIPKEOGD_02491 1.2e-90 S ABC-2 family transporter protein
IIPKEOGD_02492 5.7e-58 S ABC-2 family transporter protein
IIPKEOGD_02493 4.6e-91 V ABC transporter, ATP-binding protein
IIPKEOGD_02494 8.8e-40
IIPKEOGD_02495 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IIPKEOGD_02496 4.9e-172 K AI-2E family transporter
IIPKEOGD_02497 1.7e-210 xylR GK ROK family
IIPKEOGD_02498 2.3e-81
IIPKEOGD_02499 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IIPKEOGD_02500 3.9e-162
IIPKEOGD_02501 3.2e-200 KLT Protein tyrosine kinase
IIPKEOGD_02502 2.9e-23 S Protein of unknown function (DUF4064)
IIPKEOGD_02503 6e-97 S Domain of unknown function (DUF4352)
IIPKEOGD_02504 3.9e-75 S Psort location Cytoplasmic, score
IIPKEOGD_02505 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIPKEOGD_02506 4.3e-144 yxeH S hydrolase
IIPKEOGD_02507 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IIPKEOGD_02508 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IIPKEOGD_02509 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
IIPKEOGD_02510 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
IIPKEOGD_02511 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IIPKEOGD_02512 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IIPKEOGD_02513 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
IIPKEOGD_02514 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
IIPKEOGD_02515 1.1e-231 gatC G PTS system sugar-specific permease component
IIPKEOGD_02516 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
IIPKEOGD_02517 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IIPKEOGD_02518 7e-112 K DeoR C terminal sensor domain
IIPKEOGD_02519 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IIPKEOGD_02520 7.4e-136 K Helix-turn-helix domain, rpiR family
IIPKEOGD_02521 3.7e-72 yueI S Protein of unknown function (DUF1694)
IIPKEOGD_02522 2.6e-38 I alpha/beta hydrolase fold
IIPKEOGD_02523 1.6e-99 I alpha/beta hydrolase fold
IIPKEOGD_02524 1.3e-159 I alpha/beta hydrolase fold
IIPKEOGD_02525 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IIPKEOGD_02526 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIPKEOGD_02527 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
IIPKEOGD_02528 5.4e-153 nanK GK ROK family
IIPKEOGD_02529 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IIPKEOGD_02530 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IIPKEOGD_02531 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
IIPKEOGD_02532 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
IIPKEOGD_02533 3.7e-44
IIPKEOGD_02534 3.2e-20 zmp1 O Zinc-dependent metalloprotease
IIPKEOGD_02535 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IIPKEOGD_02536 4.2e-310 mco Q Multicopper oxidase
IIPKEOGD_02537 1.1e-54 ypaA S Protein of unknown function (DUF1304)
IIPKEOGD_02538 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
IIPKEOGD_02539 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
IIPKEOGD_02540 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
IIPKEOGD_02541 9.3e-80
IIPKEOGD_02542 2.7e-68 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IIPKEOGD_02543 4.5e-174 rihC 3.2.2.1 F Nucleoside
IIPKEOGD_02544 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
IIPKEOGD_02545 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
IIPKEOGD_02546 1.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
IIPKEOGD_02547 9.9e-180 proV E ABC transporter, ATP-binding protein
IIPKEOGD_02548 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
IIPKEOGD_02549 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IIPKEOGD_02550 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
IIPKEOGD_02551 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IIPKEOGD_02552 1.1e-235 M domain protein
IIPKEOGD_02553 5.1e-52 U domain, Protein
IIPKEOGD_02554 4.4e-25 S Immunity protein 74
IIPKEOGD_02555 2.9e-131 ydfG S KR domain
IIPKEOGD_02556 8.3e-63 hxlR K HxlR-like helix-turn-helix
IIPKEOGD_02557 1e-47 S Domain of unknown function (DUF1905)
IIPKEOGD_02558 0.0 M Glycosyl hydrolases family 25
IIPKEOGD_02559 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IIPKEOGD_02560 2e-166 GM NmrA-like family
IIPKEOGD_02561 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
IIPKEOGD_02562 4.3e-204 2.7.13.3 T GHKL domain
IIPKEOGD_02563 8.2e-134 K LytTr DNA-binding domain
IIPKEOGD_02564 0.0 asnB 6.3.5.4 E Asparagine synthase
IIPKEOGD_02565 1.4e-94 M ErfK YbiS YcfS YnhG
IIPKEOGD_02566 5.1e-210 ytbD EGP Major facilitator Superfamily
IIPKEOGD_02567 2e-61 K Transcriptional regulator, HxlR family
IIPKEOGD_02568 1e-116 S Haloacid dehalogenase-like hydrolase
IIPKEOGD_02569 5.9e-117
IIPKEOGD_02570 6.9e-210 NU Mycoplasma protein of unknown function, DUF285
IIPKEOGD_02571 1.1e-62
IIPKEOGD_02572 2.2e-100 S WxL domain surface cell wall-binding
IIPKEOGD_02573 2.4e-187 S Cell surface protein
IIPKEOGD_02574 1.8e-113 S GyrI-like small molecule binding domain
IIPKEOGD_02575 1.3e-66 S Iron-sulphur cluster biosynthesis
IIPKEOGD_02576 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
IIPKEOGD_02577 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IIPKEOGD_02578 1.5e-261 frdC 1.3.5.4 C FAD binding domain
IIPKEOGD_02579 1e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IIPKEOGD_02580 4.9e-162 mleR K LysR family transcriptional regulator
IIPKEOGD_02581 1.2e-166 mleR K LysR family
IIPKEOGD_02582 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
IIPKEOGD_02583 1.4e-165 mleP S Sodium Bile acid symporter family
IIPKEOGD_02584 5.8e-253 yfnA E Amino Acid
IIPKEOGD_02585 3e-99 S ECF transporter, substrate-specific component
IIPKEOGD_02586 1.8e-23
IIPKEOGD_02587 9.4e-297 S Alpha beta
IIPKEOGD_02588 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
IIPKEOGD_02589 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IIPKEOGD_02590 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IIPKEOGD_02591 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IIPKEOGD_02592 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
IIPKEOGD_02593 2.4e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IIPKEOGD_02594 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IIPKEOGD_02595 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IIPKEOGD_02596 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IIPKEOGD_02597 2.4e-113 ywnB S NAD(P)H-binding
IIPKEOGD_02598 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
IIPKEOGD_02600 1.1e-161 rrmA 2.1.1.187 H Methyltransferase
IIPKEOGD_02601 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IIPKEOGD_02602 4.3e-206 XK27_05220 S AI-2E family transporter
IIPKEOGD_02603 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IIPKEOGD_02604 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IIPKEOGD_02605 1.1e-115 cutC P Participates in the control of copper homeostasis
IIPKEOGD_02606 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
IIPKEOGD_02607 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IIPKEOGD_02608 6e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
IIPKEOGD_02609 3.6e-114 yjbH Q Thioredoxin
IIPKEOGD_02610 0.0 pepF E oligoendopeptidase F
IIPKEOGD_02611 2e-180 coiA 3.6.4.12 S Competence protein
IIPKEOGD_02612 2e-13 coiA 3.6.4.12 S Competence protein
IIPKEOGD_02613 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IIPKEOGD_02614 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IIPKEOGD_02615 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
IIPKEOGD_02616 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
IIPKEOGD_02624 5.5e-08
IIPKEOGD_02631 1.8e-84 hmpT S Pfam:DUF3816
IIPKEOGD_02632 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IIPKEOGD_02633 3.9e-111
IIPKEOGD_02634 2.4e-149 M Glycosyl hydrolases family 25
IIPKEOGD_02635 2e-143 yvpB S Peptidase_C39 like family
IIPKEOGD_02636 1.1e-92 yueI S Protein of unknown function (DUF1694)
IIPKEOGD_02637 1.6e-115 S Protein of unknown function (DUF554)
IIPKEOGD_02638 6.4e-148 KT helix_turn_helix, mercury resistance
IIPKEOGD_02639 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
IIPKEOGD_02640 6.6e-95 S Protein of unknown function (DUF1440)
IIPKEOGD_02641 5.2e-174 hrtB V ABC transporter permease
IIPKEOGD_02642 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IIPKEOGD_02643 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
IIPKEOGD_02644 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
IIPKEOGD_02645 8.1e-99 1.5.1.3 H RibD C-terminal domain
IIPKEOGD_02646 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IIPKEOGD_02647 6.4e-117 S Membrane
IIPKEOGD_02648 1.2e-155 mleP3 S Membrane transport protein
IIPKEOGD_02649 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
IIPKEOGD_02650 7.4e-67 gcvH E Glycine cleavage H-protein
IIPKEOGD_02651 2.8e-176 sepS16B
IIPKEOGD_02652 1.8e-130
IIPKEOGD_02653 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
IIPKEOGD_02654 6.8e-57
IIPKEOGD_02655 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIPKEOGD_02656 4.9e-24 elaA S GNAT family
IIPKEOGD_02657 8.4e-75 K Transcriptional regulator
IIPKEOGD_02658 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
IIPKEOGD_02659 4.3e-40
IIPKEOGD_02660 1.5e-205 potD P ABC transporter
IIPKEOGD_02661 2.9e-140 potC P ABC transporter permease
IIPKEOGD_02662 4.5e-149 potB P ABC transporter permease
IIPKEOGD_02663 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IIPKEOGD_02664 1.3e-96 puuR K Cupin domain
IIPKEOGD_02665 1.1e-83 6.3.3.2 S ASCH
IIPKEOGD_02666 1e-84 K GNAT family
IIPKEOGD_02667 8e-91 K acetyltransferase
IIPKEOGD_02668 8.1e-22
IIPKEOGD_02669 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
IIPKEOGD_02670 2e-163 ytrB V ABC transporter
IIPKEOGD_02671 4.9e-190
IIPKEOGD_02672 4.7e-241 amtB P ammonium transporter
IIPKEOGD_02673 1.3e-257 P Major Facilitator Superfamily
IIPKEOGD_02674 2.8e-91 K Transcriptional regulator PadR-like family
IIPKEOGD_02675 8.4e-44
IIPKEOGD_02676 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
IIPKEOGD_02677 6e-154 tagG U Transport permease protein
IIPKEOGD_02678 3.8e-218
IIPKEOGD_02679 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
IIPKEOGD_02680 1.8e-61 S CHY zinc finger
IIPKEOGD_02681 1.1e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IIPKEOGD_02682 5.7e-95 bioY S BioY family
IIPKEOGD_02683 3e-40
IIPKEOGD_02684 6.5e-281 pipD E Dipeptidase
IIPKEOGD_02685 1.1e-29
IIPKEOGD_02686 8.7e-122 qmcA O prohibitin homologues
IIPKEOGD_02687 1.5e-239 xylP1 G MFS/sugar transport protein
IIPKEOGD_02689 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IIPKEOGD_02690 1.8e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
IIPKEOGD_02691 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IIPKEOGD_02692 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IIPKEOGD_02693 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IIPKEOGD_02694 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IIPKEOGD_02695 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IIPKEOGD_02696 9.3e-109 tdk 2.7.1.21 F thymidine kinase
IIPKEOGD_02697 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IIPKEOGD_02698 6.5e-136 cobQ S glutamine amidotransferase
IIPKEOGD_02699 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
IIPKEOGD_02700 1.2e-191 ampC V Beta-lactamase
IIPKEOGD_02701 5.2e-29
IIPKEOGD_02702 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
IIPKEOGD_02703 1.9e-58
IIPKEOGD_02704 2.8e-126
IIPKEOGD_02705 0.0 yfiC V ABC transporter
IIPKEOGD_02706 2.2e-310 ycfI V ABC transporter, ATP-binding protein
IIPKEOGD_02707 3.3e-65 S Protein of unknown function (DUF1093)
IIPKEOGD_02708 1.3e-132 yxkH G Polysaccharide deacetylase
IIPKEOGD_02710 2.3e-219 S Bacterial membrane protein YfhO
IIPKEOGD_02711 1.2e-225 nupG F Nucleoside
IIPKEOGD_02712 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IIPKEOGD_02713 7.9e-149 noc K Belongs to the ParB family
IIPKEOGD_02714 1.8e-136 soj D Sporulation initiation inhibitor
IIPKEOGD_02715 2.4e-156 spo0J K Belongs to the ParB family
IIPKEOGD_02716 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
IIPKEOGD_02717 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IIPKEOGD_02718 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
IIPKEOGD_02719 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IIPKEOGD_02720 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IIPKEOGD_02721 5.5e-124 yoaK S Protein of unknown function (DUF1275)
IIPKEOGD_02722 3.2e-124 K response regulator
IIPKEOGD_02723 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
IIPKEOGD_02724 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IIPKEOGD_02725 3.2e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
IIPKEOGD_02726 5.1e-131 azlC E branched-chain amino acid
IIPKEOGD_02727 2.3e-54 azlD S branched-chain amino acid
IIPKEOGD_02728 5.2e-109 S membrane transporter protein
IIPKEOGD_02729 2.6e-30
IIPKEOGD_02730 0.0 lacA 3.2.1.23 G -beta-galactosidase
IIPKEOGD_02731 0.0 lacS G Transporter
IIPKEOGD_02732 1e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
IIPKEOGD_02733 1e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IIPKEOGD_02735 0.0 O Belongs to the peptidase S8 family
IIPKEOGD_02736 5.3e-19
IIPKEOGD_02737 2.6e-79
IIPKEOGD_02738 2.8e-21 L Transposase
IIPKEOGD_02739 2.5e-175 nsr 3.4.21.102 M Peptidase family S41
IIPKEOGD_02740 2.3e-96 K Helix-turn-helix domain
IIPKEOGD_02742 1.2e-29
IIPKEOGD_02743 6.8e-10 K Helix-turn-helix XRE-family like proteins
IIPKEOGD_02744 4.8e-62 S Protein of unknown function (DUF2992)
IIPKEOGD_02745 3.2e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
IIPKEOGD_02746 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IIPKEOGD_02747 2.8e-105 L Integrase
IIPKEOGD_02748 6.1e-45 S Phage derived protein Gp49-like (DUF891)
IIPKEOGD_02749 1.7e-36 K sequence-specific DNA binding
IIPKEOGD_02750 1.1e-54 S Bacterial mobilisation protein (MobC)
IIPKEOGD_02751 1.6e-184 U Relaxase/Mobilisation nuclease domain
IIPKEOGD_02752 2.8e-55 repA S Replication initiator protein A
IIPKEOGD_02753 2.7e-42
IIPKEOGD_02754 0.0 pacL 3.6.3.8 P P-type ATPase
IIPKEOGD_02756 6.2e-44 S Psort location CytoplasmicMembrane, score
IIPKEOGD_02757 2.1e-20 3.4.21.19 M Belongs to the peptidase S1B family
IIPKEOGD_02758 8.3e-17 S Protein of unknown function (DUF1093)
IIPKEOGD_02759 6.1e-55 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IIPKEOGD_02760 9e-33
IIPKEOGD_02761 3.7e-194 L Psort location Cytoplasmic, score
IIPKEOGD_02762 1.2e-129 3.1.21.3 V type I restriction modification DNA specificity domain protein
IIPKEOGD_02763 1.3e-301 hsdM 2.1.1.72 V type I restriction-modification system
IIPKEOGD_02764 0.0 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IIPKEOGD_02765 2.7e-10
IIPKEOGD_02766 7e-73
IIPKEOGD_02767 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
IIPKEOGD_02768 4e-281 1.3.5.4 C FAD binding domain
IIPKEOGD_02769 1.8e-159 K LysR substrate binding domain
IIPKEOGD_02770 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
IIPKEOGD_02771 2.5e-289 yjcE P Sodium proton antiporter
IIPKEOGD_02772 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IIPKEOGD_02773 8.1e-117 K Bacterial regulatory proteins, tetR family
IIPKEOGD_02774 3.1e-51 NU Mycoplasma protein of unknown function, DUF285
IIPKEOGD_02775 0.0 3.2.1.96 G Glycosyl hydrolase family 85
IIPKEOGD_02776 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IIPKEOGD_02777 4e-209 msmK P Belongs to the ABC transporter superfamily
IIPKEOGD_02778 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
IIPKEOGD_02779 1.6e-149 malA S maltodextrose utilization protein MalA
IIPKEOGD_02780 1.4e-161 malD P ABC transporter permease
IIPKEOGD_02781 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
IIPKEOGD_02782 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
IIPKEOGD_02783 7.3e-86 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
IIPKEOGD_02784 0.0 pepN 3.4.11.2 E aminopeptidase
IIPKEOGD_02785 1.1e-101 G Glycogen debranching enzyme
IIPKEOGD_02786 3.4e-10 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
IIPKEOGD_02787 1.5e-154 yjdB S Domain of unknown function (DUF4767)
IIPKEOGD_02788 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
IIPKEOGD_02789 5.3e-72 asp2 S Asp23 family, cell envelope-related function
IIPKEOGD_02790 8.7e-72 asp S Asp23 family, cell envelope-related function
IIPKEOGD_02791 7.2e-23
IIPKEOGD_02792 4.4e-84
IIPKEOGD_02793 7.1e-37 S Transglycosylase associated protein
IIPKEOGD_02794 0.0 XK27_09800 I Acyltransferase family
IIPKEOGD_02795 1.1e-36 S MORN repeat
IIPKEOGD_02796 4.6e-25 S Cysteine-rich secretory protein family
IIPKEOGD_02797 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
IIPKEOGD_02798 1.4e-77
IIPKEOGD_02799 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
IIPKEOGD_02800 3.3e-97 FG HIT domain
IIPKEOGD_02801 1.7e-173 S Aldo keto reductase
IIPKEOGD_02802 1.9e-52 yitW S Pfam:DUF59
IIPKEOGD_02803 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IIPKEOGD_02804 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
IIPKEOGD_02805 5e-195 blaA6 V Beta-lactamase
IIPKEOGD_02806 6.2e-96 V VanZ like family
IIPKEOGD_02807 1.7e-101 S WxL domain surface cell wall-binding
IIPKEOGD_02808 3.6e-183 S Cell surface protein
IIPKEOGD_02809 8.4e-75
IIPKEOGD_02810 8.4e-263
IIPKEOGD_02811 2.3e-227 hpk9 2.7.13.3 T GHKL domain
IIPKEOGD_02812 2.9e-38 S TfoX C-terminal domain
IIPKEOGD_02813 6e-140 K Helix-turn-helix domain
IIPKEOGD_02814 2.2e-126
IIPKEOGD_02815 1.1e-184 S DUF218 domain
IIPKEOGD_02816 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IIPKEOGD_02817 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
IIPKEOGD_02818 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IIPKEOGD_02819 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IIPKEOGD_02820 2.1e-31
IIPKEOGD_02821 1.7e-43 ankB S ankyrin repeats
IIPKEOGD_02822 6.5e-91 S ECF-type riboflavin transporter, S component
IIPKEOGD_02823 4.2e-47
IIPKEOGD_02824 9.8e-214 yceI EGP Major facilitator Superfamily
IIPKEOGD_02825 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
IIPKEOGD_02826 3.8e-23
IIPKEOGD_02828 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_02829 8.2e-173 ykfC 3.4.14.13 M NlpC/P60 family
IIPKEOGD_02830 3.3e-80 K AsnC family
IIPKEOGD_02831 2e-35
IIPKEOGD_02832 3.3e-33
IIPKEOGD_02833 5.6e-217 2.7.7.65 T diguanylate cyclase
IIPKEOGD_02834 1.6e-67 M Cna protein B-type domain
IIPKEOGD_02835 3.2e-256 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IIPKEOGD_02836 1.8e-309 traA L MobA MobL family protein
IIPKEOGD_02837 6.2e-32
IIPKEOGD_02838 9e-14 Q Methyltransferase
IIPKEOGD_02840 2.6e-169 EG EamA-like transporter family
IIPKEOGD_02841 2.3e-38 gcvR T Belongs to the UPF0237 family
IIPKEOGD_02842 3e-243 XK27_08635 S UPF0210 protein
IIPKEOGD_02843 1.6e-134 K response regulator
IIPKEOGD_02844 2.9e-287 yclK 2.7.13.3 T Histidine kinase
IIPKEOGD_02845 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
IIPKEOGD_02846 9.7e-155 glcU U sugar transport
IIPKEOGD_02847 2.8e-88
IIPKEOGD_02848 2.9e-176 L Initiator Replication protein
IIPKEOGD_02849 2.5e-29
IIPKEOGD_02850 2.3e-107 L Integrase
IIPKEOGD_02851 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
IIPKEOGD_02852 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IIPKEOGD_02853 0.0 ybfG M peptidoglycan-binding domain-containing protein
IIPKEOGD_02856 1.2e-26
IIPKEOGD_02857 2.6e-40
IIPKEOGD_02858 7.6e-110 XK27_07075 V CAAX protease self-immunity
IIPKEOGD_02859 1.1e-56 hxlR K HxlR-like helix-turn-helix
IIPKEOGD_02860 1.5e-129 L Helix-turn-helix domain
IIPKEOGD_02861 1.7e-159 L hmm pf00665
IIPKEOGD_02862 6.7e-232 EGP Major facilitator Superfamily
IIPKEOGD_02865 1.5e-42 S COG NOG38524 non supervised orthologous group
IIPKEOGD_02866 8.3e-38 KT PspC domain protein
IIPKEOGD_02867 3e-80 ydhK M Protein of unknown function (DUF1541)
IIPKEOGD_02868 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
IIPKEOGD_02869 5.1e-15
IIPKEOGD_02870 4.7e-97 K Bacterial regulatory proteins, tetR family
IIPKEOGD_02871 7.3e-59 dhaM 2.7.1.121 S PTS system fructose IIA component
IIPKEOGD_02872 3.6e-100 dhaL 2.7.1.121 S Dak2
IIPKEOGD_02873 2.1e-188 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
IIPKEOGD_02874 7.9e-60 mleR K LysR substrate binding domain
IIPKEOGD_02875 5.4e-132 K LysR family
IIPKEOGD_02876 2.4e-301 1.3.5.4 C FMN_bind
IIPKEOGD_02877 2.8e-239 P Sodium:sulfate symporter transmembrane region
IIPKEOGD_02878 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
IIPKEOGD_02879 2.2e-99 padR K Virulence activator alpha C-term
IIPKEOGD_02880 2.7e-79 T Universal stress protein family
IIPKEOGD_02881 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IIPKEOGD_02883 5.4e-64 tcmJ G COG0662 Mannose-6-phosphate isomerase
IIPKEOGD_02884 6.4e-46 M domain protein
IIPKEOGD_02885 6e-52 ykoF S YKOF-related Family
IIPKEOGD_02886 3.3e-11 glnA 6.3.1.2 E glutamine synthetase
IIPKEOGD_02887 1.5e-193 glnA 6.3.1.2 E glutamine synthetase
IIPKEOGD_02888 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IIPKEOGD_02889 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
IIPKEOGD_02890 2.3e-107 L Integrase
IIPKEOGD_02891 4.9e-16
IIPKEOGD_02892 5.5e-18
IIPKEOGD_02893 1.2e-123 repA S Replication initiator protein A
IIPKEOGD_02894 6.7e-246 cycA E Amino acid permease
IIPKEOGD_02895 0.0 rafA 3.2.1.22 G alpha-galactosidase
IIPKEOGD_02896 9.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IIPKEOGD_02897 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IIPKEOGD_02898 1e-96 tnpR1 L Resolvase, N terminal domain
IIPKEOGD_02899 6.2e-57 T Belongs to the universal stress protein A family
IIPKEOGD_02900 1.5e-249 mntH P H( )-stimulated, divalent metal cation uptake system
IIPKEOGD_02901 2.9e-38 sirR K Helix-turn-helix diphteria tox regulatory element
IIPKEOGD_02903 2.2e-75 K Copper transport repressor CopY TcrY
IIPKEOGD_02904 0.0 copB 3.6.3.4 P P-type ATPase
IIPKEOGD_02905 2.8e-117 mdt(A) EGP Major facilitator Superfamily
IIPKEOGD_02906 1.5e-65 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IIPKEOGD_02907 4.5e-238 asdA 4.1.1.12 E Aminotransferase class I and II
IIPKEOGD_02908 1.2e-198 aspT U Predicted Permease Membrane Region
IIPKEOGD_02909 1.5e-65
IIPKEOGD_02910 1.3e-117
IIPKEOGD_02912 4.7e-25
IIPKEOGD_02913 0.0 mco Q Multicopper oxidase
IIPKEOGD_02914 3e-238 EGP Major Facilitator Superfamily
IIPKEOGD_02915 1.9e-54
IIPKEOGD_02916 7.4e-57 L Transposase IS66 family
IIPKEOGD_02917 1.5e-194 pbuX F xanthine permease
IIPKEOGD_02918 3.7e-24
IIPKEOGD_02919 1.9e-56 XK27_01125 L PFAM IS66 Orf2 family protein
IIPKEOGD_02920 8e-18
IIPKEOGD_02923 5.2e-34
IIPKEOGD_02924 4.2e-144 soj D AAA domain
IIPKEOGD_02925 4.9e-38 KT Transcriptional regulatory protein, C terminal
IIPKEOGD_02926 0.0 kup P Transport of potassium into the cell
IIPKEOGD_02927 7.6e-55 K helix_turn_helix multiple antibiotic resistance protein
IIPKEOGD_02928 1.3e-14 3.3.1.1 H adenosylhomocysteinase activity
IIPKEOGD_02929 2.4e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IIPKEOGD_02930 2.8e-220 EGP Major facilitator Superfamily
IIPKEOGD_02931 2.3e-53 XK27_02070 S Nitroreductase
IIPKEOGD_02932 0.0 lacS G Transporter
IIPKEOGD_02933 1.9e-136 bgaR K helix_turn_helix, arabinose operon control protein
IIPKEOGD_02934 9.1e-153 cjaA ET ABC transporter substrate-binding protein
IIPKEOGD_02935 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IIPKEOGD_02936 4.3e-113 P ABC transporter permease
IIPKEOGD_02937 4.2e-113 papP P ABC transporter, permease protein
IIPKEOGD_02938 8e-68 C lyase activity
IIPKEOGD_02939 2e-184 L Psort location Cytoplasmic, score
IIPKEOGD_02940 1.7e-18
IIPKEOGD_02942 2.6e-47 S Family of unknown function (DUF5388)
IIPKEOGD_02943 1.6e-146 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IIPKEOGD_02944 4.8e-94 K Bacterial regulatory proteins, tetR family
IIPKEOGD_02945 1.2e-191 1.1.1.219 GM Male sterility protein
IIPKEOGD_02946 1.6e-100 S Protein of unknown function (DUF1211)
IIPKEOGD_02947 2.7e-27 hol S Bacteriophage holin
IIPKEOGD_02948 3.3e-61 V Abortive infection bacteriophage resistance protein
IIPKEOGD_02949 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
IIPKEOGD_02950 5.7e-86
IIPKEOGD_02951 1.2e-40
IIPKEOGD_02952 7.9e-26
IIPKEOGD_02953 2.6e-40
IIPKEOGD_02954 2.9e-125 S Phage Mu protein F like protein
IIPKEOGD_02955 1.2e-12 ytgB S Transglycosylase associated protein
IIPKEOGD_02956 8.8e-95 L 4.5 Transposon and IS
IIPKEOGD_02957 1.6e-39 L Transposase
IIPKEOGD_02959 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IIPKEOGD_02960 1.5e-15 S Alpha/beta hydrolase of unknown function (DUF915)
IIPKEOGD_02961 1.2e-23 S Family of unknown function (DUF5388)
IIPKEOGD_02962 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IIPKEOGD_02963 6.6e-136 L Replication protein
IIPKEOGD_02964 2.1e-11
IIPKEOGD_02965 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
IIPKEOGD_02966 4.2e-150 S Uncharacterised protein, DegV family COG1307
IIPKEOGD_02967 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
IIPKEOGD_02968 3.7e-31 tnp2PF3 L manually curated
IIPKEOGD_02969 7e-57
IIPKEOGD_02970 6e-31 cspA K Cold shock protein
IIPKEOGD_02971 3.8e-40
IIPKEOGD_02972 4e-151 glcU U sugar transport
IIPKEOGD_02973 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
IIPKEOGD_02974 1.2e-103
IIPKEOGD_02975 4.4e-127 terC P integral membrane protein, YkoY family
IIPKEOGD_02977 3.1e-36 L Resolvase, N terminal domain
IIPKEOGD_02978 1.2e-163 L PFAM Integrase catalytic region
IIPKEOGD_02979 4.8e-58
IIPKEOGD_02980 4.2e-70 S Pyrimidine dimer DNA glycosylase
IIPKEOGD_02981 1.3e-23 hol S Bacteriophage holin
IIPKEOGD_02982 3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IIPKEOGD_02983 5.4e-36 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IIPKEOGD_02985 2.9e-13
IIPKEOGD_02987 2.7e-31 L Transposase
IIPKEOGD_02988 1.7e-88 L Helix-turn-helix domain
IIPKEOGD_02989 1.7e-90 L Transposase and inactivated derivatives, IS30 family
IIPKEOGD_02990 4.6e-82 tnp2PF3 L Transposase DDE domain
IIPKEOGD_02991 1.7e-81 tnp L DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)