ORF_ID e_value Gene_name EC_number CAZy COGs Description
MKDMMHLC_00001 2.8e-241 M Glycosyltransferase, group 2 family protein
MKDMMHLC_00002 1.7e-72 S SnoaL-like domain
MKDMMHLC_00003 2.8e-145 yjfP S COG1073 Hydrolases of the alpha beta superfamily
MKDMMHLC_00004 6.1e-244 P Major Facilitator Superfamily
MKDMMHLC_00005 1.2e-46 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_00006 1.8e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MKDMMHLC_00008 3.2e-56 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MKDMMHLC_00009 8.3e-110 ypsA S Belongs to the UPF0398 family
MKDMMHLC_00010 7.6e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MKDMMHLC_00011 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MKDMMHLC_00012 7e-178 phnT 3.6.3.30 P ATPases associated with a variety of cellular activities
MKDMMHLC_00013 4.9e-182 ftpB P Bacterial extracellular solute-binding protein
MKDMMHLC_00014 1.2e-302 ftpA P Binding-protein-dependent transport system inner membrane component
MKDMMHLC_00015 4.4e-83 uspA T Universal stress protein family
MKDMMHLC_00016 2.1e-157 metQ_4 P Belongs to the nlpA lipoprotein family
MKDMMHLC_00017 2e-99 metI P ABC transporter permease
MKDMMHLC_00018 7e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKDMMHLC_00020 1.1e-127 dnaD L Replication initiation and membrane attachment
MKDMMHLC_00021 5.4e-258 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MKDMMHLC_00022 1.1e-225 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
MKDMMHLC_00023 2.1e-72 ypmB S protein conserved in bacteria
MKDMMHLC_00024 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MKDMMHLC_00025 4e-170 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MKDMMHLC_00026 7.4e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MKDMMHLC_00027 1.1e-203 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MKDMMHLC_00028 9.6e-197 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MKDMMHLC_00029 3e-195 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MKDMMHLC_00030 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MKDMMHLC_00031 2.5e-250 malT G Major Facilitator
MKDMMHLC_00032 1.5e-89 S Domain of unknown function (DUF4767)
MKDMMHLC_00033 2.3e-267 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MKDMMHLC_00034 1.2e-149 yitU 3.1.3.104 S hydrolase
MKDMMHLC_00035 1.4e-265 yfnA E Amino Acid
MKDMMHLC_00036 3.3e-258 gabT 2.6.1.19, 5.1.1.21 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MKDMMHLC_00037 2.4e-43
MKDMMHLC_00038 1.9e-49
MKDMMHLC_00039 1.4e-136 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 U Ion channel
MKDMMHLC_00040 1.4e-170 2.5.1.74 H UbiA prenyltransferase family
MKDMMHLC_00041 2.7e-252 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MKDMMHLC_00042 1.8e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MKDMMHLC_00043 8.6e-281 pipD E Dipeptidase
MKDMMHLC_00044 9.4e-40
MKDMMHLC_00045 4.8e-29 S CsbD-like
MKDMMHLC_00046 6.5e-41 S transglycosylase associated protein
MKDMMHLC_00047 3.1e-14
MKDMMHLC_00048 2.9e-35
MKDMMHLC_00049 3.5e-163 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
MKDMMHLC_00050 1e-65 S Protein of unknown function (DUF805)
MKDMMHLC_00051 6.3e-76 uspA T Belongs to the universal stress protein A family
MKDMMHLC_00052 1.9e-67 tspO T TspO/MBR family
MKDMMHLC_00053 7.9e-41
MKDMMHLC_00054 3e-44 ycnE 3.1.1.29 S Antibiotic biosynthesis monooxygenase
MKDMMHLC_00055 4.5e-114 1.14.99.53 AA10 S Lytic polysaccharide mono-oxygenase, cellulose-degrading
MKDMMHLC_00056 2.3e-29 L hmm pf00665
MKDMMHLC_00057 1.8e-207 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MKDMMHLC_00058 1.3e-28
MKDMMHLC_00059 8.5e-54
MKDMMHLC_00060 1.2e-139 f42a O Band 7 protein
MKDMMHLC_00061 1.4e-301 norB EGP Major Facilitator
MKDMMHLC_00062 7.5e-92 K transcriptional regulator
MKDMMHLC_00063 1.9e-192 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKDMMHLC_00064 1.7e-87 ykhA 3.1.2.20 I Thioesterase superfamily
MKDMMHLC_00065 1.6e-160 K LysR substrate binding domain
MKDMMHLC_00066 2.2e-123 S Protein of unknown function (DUF554)
MKDMMHLC_00067 1.4e-98 2.7.8.7 H Belongs to the P-Pant transferase superfamily
MKDMMHLC_00068 1.5e-135 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MKDMMHLC_00069 3e-139 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MKDMMHLC_00070 1.6e-157 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKDMMHLC_00071 1.2e-260 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MKDMMHLC_00072 6.1e-70 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
MKDMMHLC_00073 2.3e-73 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKDMMHLC_00074 1.4e-226 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
MKDMMHLC_00075 2.1e-126 IQ reductase
MKDMMHLC_00076 1.3e-168 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
MKDMMHLC_00077 3.8e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKDMMHLC_00078 2.9e-179 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKDMMHLC_00079 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MKDMMHLC_00080 1.1e-178 yneE K Transcriptional regulator
MKDMMHLC_00081 3e-145 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDMMHLC_00083 2.1e-58 S Protein of unknown function (DUF1648)
MKDMMHLC_00084 5.1e-198 adhB 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MKDMMHLC_00085 1.3e-215 3.5.1.47 E Peptidase family M20/M25/M40
MKDMMHLC_00086 5.8e-217 E glutamate:sodium symporter activity
MKDMMHLC_00087 1.6e-67 ybbJ K Acetyltransferase (GNAT) family
MKDMMHLC_00088 4.8e-165 1.6.5.5 C Zinc-binding dehydrogenase
MKDMMHLC_00089 2e-97 entB 3.5.1.19 Q Isochorismatase family
MKDMMHLC_00090 3.9e-142 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
MKDMMHLC_00091 3e-226 trpB 4.2.1.20 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
MKDMMHLC_00092 4.1e-110 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
MKDMMHLC_00093 1.4e-128 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
MKDMMHLC_00094 1.2e-167 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MKDMMHLC_00095 1.5e-104 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH Peptidase C26
MKDMMHLC_00096 5.4e-267 trpE 4.1.3.27 EH Anthranilate synthase component I, N terminal region
MKDMMHLC_00098 1.5e-270 XK27_00765
MKDMMHLC_00099 2.3e-139 ecsA_2 V AAA domain, putative AbiEii toxin, Type IV TA system
MKDMMHLC_00100 5.3e-86
MKDMMHLC_00101 6.4e-156 pelX UW LPXTG-motif cell wall anchor domain protein
MKDMMHLC_00102 6.8e-53
MKDMMHLC_00103 1.9e-59 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MKDMMHLC_00104 3.4e-140 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MKDMMHLC_00105 1.4e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MKDMMHLC_00106 2.6e-39 ylqC S Belongs to the UPF0109 family
MKDMMHLC_00107 2.9e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MKDMMHLC_00108 1.1e-219 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MKDMMHLC_00109 2.6e-58 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MKDMMHLC_00110 1.9e-169 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MKDMMHLC_00111 0.0 smc D Required for chromosome condensation and partitioning
MKDMMHLC_00112 5.7e-129 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MKDMMHLC_00113 1.7e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MKDMMHLC_00114 2.3e-190 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MKDMMHLC_00115 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MKDMMHLC_00116 0.0 yloV S DAK2 domain fusion protein YloV
MKDMMHLC_00117 1.8e-57 asp S Asp23 family, cell envelope-related function
MKDMMHLC_00118 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MKDMMHLC_00119 3.4e-123 thiN 2.7.6.2 H thiamine pyrophosphokinase
MKDMMHLC_00120 2.8e-117 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MKDMMHLC_00121 3.2e-164 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MKDMMHLC_00122 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
MKDMMHLC_00123 1.7e-134 stp 3.1.3.16 T phosphatase
MKDMMHLC_00124 3e-251 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MKDMMHLC_00125 1.8e-173 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MKDMMHLC_00126 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MKDMMHLC_00127 8.8e-218 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MKDMMHLC_00128 2.4e-30 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MKDMMHLC_00129 3.3e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MKDMMHLC_00130 4.5e-55
MKDMMHLC_00131 4.9e-106 opuCD P Binding-protein-dependent transport system inner membrane component
MKDMMHLC_00132 6e-174 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKDMMHLC_00133 1.2e-104 opuCB E ABC transporter permease
MKDMMHLC_00134 5.7e-222 opuCA 3.6.3.32 E ABC transporter, ATP-binding protein
MKDMMHLC_00135 4.4e-308 recN L May be involved in recombinational repair of damaged DNA
MKDMMHLC_00136 2.2e-76 argR K Regulates arginine biosynthesis genes
MKDMMHLC_00137 4e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MKDMMHLC_00138 5.5e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKDMMHLC_00139 4.3e-33 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKDMMHLC_00140 7.9e-244 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MKDMMHLC_00141 2.2e-151 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MKDMMHLC_00142 5.2e-69 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MKDMMHLC_00143 3.5e-74 yqhY S Asp23 family, cell envelope-related function
MKDMMHLC_00144 2.2e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MKDMMHLC_00145 3.8e-193 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKDMMHLC_00146 5.4e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MKDMMHLC_00147 3.2e-53 ysxB J Cysteine protease Prp
MKDMMHLC_00148 7.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
MKDMMHLC_00149 1.8e-89 K Transcriptional regulator
MKDMMHLC_00150 5.4e-19
MKDMMHLC_00153 1.7e-30
MKDMMHLC_00154 5.3e-56
MKDMMHLC_00155 2.4e-98 dut S Protein conserved in bacteria
MKDMMHLC_00156 4e-181
MKDMMHLC_00157 2e-161
MKDMMHLC_00158 3.1e-264 glnA 6.3.1.2 E glutamine synthetase
MKDMMHLC_00159 4.6e-64 glnR K Transcriptional regulator
MKDMMHLC_00160 1.6e-174 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MKDMMHLC_00161 5.8e-140 glpQ 3.1.4.46 C phosphodiesterase
MKDMMHLC_00162 6.9e-23 WQ51_02665 S Protein of unknown function (DUF3042)
MKDMMHLC_00163 4.4e-68 yqhL P Rhodanese-like protein
MKDMMHLC_00164 6.4e-111 pepE 3.4.13.21 E Belongs to the peptidase S51 family
MKDMMHLC_00165 5.7e-180 glk 2.7.1.2 G Glucokinase
MKDMMHLC_00166 1.4e-33 yqgQ S Bacterial protein of unknown function (DUF910)
MKDMMHLC_00167 1.3e-114 gluP 3.4.21.105 S Peptidase, S54 family
MKDMMHLC_00168 6.3e-102 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MKDMMHLC_00169 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MKDMMHLC_00170 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MKDMMHLC_00171 0.0 S membrane
MKDMMHLC_00172 1.5e-54 yneR S Belongs to the HesB IscA family
MKDMMHLC_00173 4e-75 XK27_02470 K LytTr DNA-binding domain
MKDMMHLC_00174 2.3e-96 liaI S membrane
MKDMMHLC_00175 6.8e-81 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKDMMHLC_00176 2.6e-112 udk 2.7.1.48 F Cytidine monophosphokinase
MKDMMHLC_00177 6.6e-186 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MKDMMHLC_00178 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKDMMHLC_00179 4.9e-201 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MKDMMHLC_00180 1.1e-62 yodB K Transcriptional regulator, HxlR family
MKDMMHLC_00181 1.3e-93 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKDMMHLC_00182 7.9e-140 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKDMMHLC_00183 6.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MKDMMHLC_00184 5.9e-150 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKDMMHLC_00185 9.3e-93 S SdpI/YhfL protein family
MKDMMHLC_00186 1.7e-226 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MKDMMHLC_00187 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MKDMMHLC_00188 8e-307 arlS 2.7.13.3 T Histidine kinase
MKDMMHLC_00189 4.3e-121 K response regulator
MKDMMHLC_00190 1.2e-244 rarA L recombination factor protein RarA
MKDMMHLC_00191 1e-273 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MKDMMHLC_00192 2e-169 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKDMMHLC_00193 7e-88 S Peptidase propeptide and YPEB domain
MKDMMHLC_00194 1.6e-97 yceD S Uncharacterized ACR, COG1399
MKDMMHLC_00195 3.4e-219 ylbM S Belongs to the UPF0348 family
MKDMMHLC_00196 4.4e-140 yqeM Q Methyltransferase
MKDMMHLC_00197 2.1e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MKDMMHLC_00198 3.2e-115 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MKDMMHLC_00199 1.4e-118 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MKDMMHLC_00200 1.1e-50 yhbY J RNA-binding protein
MKDMMHLC_00201 4.5e-216 yqeH S Ribosome biogenesis GTPase YqeH
MKDMMHLC_00202 1.4e-98 yqeG S HAD phosphatase, family IIIA
MKDMMHLC_00203 1.3e-79
MKDMMHLC_00204 6.9e-222 pgaC GT2 M Glycosyl transferase
MKDMMHLC_00205 2.2e-134 racD 5.1.1.13 G Belongs to the aspartate glutamate racemases family
MKDMMHLC_00206 1e-62 hxlR K Transcriptional regulator, HxlR family
MKDMMHLC_00207 8e-196 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MKDMMHLC_00208 5e-240 yrvN L AAA C-terminal domain
MKDMMHLC_00209 1.1e-55
MKDMMHLC_00210 7.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MKDMMHLC_00211 1.9e-26 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MKDMMHLC_00212 1.8e-84 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MKDMMHLC_00213 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MKDMMHLC_00214 1.2e-171 dnaI L Primosomal protein DnaI
MKDMMHLC_00215 1.1e-248 dnaB L replication initiation and membrane attachment
MKDMMHLC_00216 4.6e-91 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MKDMMHLC_00217 1e-102 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MKDMMHLC_00218 1.5e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MKDMMHLC_00219 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MKDMMHLC_00220 4.5e-121 ybhL S Belongs to the BI1 family
MKDMMHLC_00221 3.1e-111 hipB K Helix-turn-helix
MKDMMHLC_00222 5.5e-45 yitW S Iron-sulfur cluster assembly protein
MKDMMHLC_00223 1.4e-272 sufB O assembly protein SufB
MKDMMHLC_00224 7.1e-83 nifU C SUF system FeS assembly protein, NifU family
MKDMMHLC_00225 8e-235 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MKDMMHLC_00226 2.6e-244 sufD O FeS assembly protein SufD
MKDMMHLC_00227 4.2e-144 sufC O FeS assembly ATPase SufC
MKDMMHLC_00228 1.3e-34 feoA P FeoA domain
MKDMMHLC_00229 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MKDMMHLC_00230 7.9e-21 S Virus attachment protein p12 family
MKDMMHLC_00231 1.1e-253 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MKDMMHLC_00232 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
MKDMMHLC_00233 7.4e-115 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MKDMMHLC_00234 1.6e-54 ytzB S Peptidase propeptide and YPEB domain
MKDMMHLC_00235 1.7e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MKDMMHLC_00236 3.2e-152 ytmP 2.7.1.89 M Choline/ethanolamine kinase
MKDMMHLC_00237 6.2e-224 ecsB U ABC transporter
MKDMMHLC_00238 1.6e-134 ecsA V ABC transporter, ATP-binding protein
MKDMMHLC_00239 9.9e-82 hit FG histidine triad
MKDMMHLC_00240 2e-42
MKDMMHLC_00241 3.3e-129 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKDMMHLC_00242 7.8e-121 draG 3.2.2.24 O ADP-ribosylglycohydrolase
MKDMMHLC_00243 3.5e-78 S WxL domain surface cell wall-binding
MKDMMHLC_00244 4e-103 S WxL domain surface cell wall-binding
MKDMMHLC_00245 9.3e-192 S Fn3-like domain
MKDMMHLC_00246 3.5e-61
MKDMMHLC_00247 0.0
MKDMMHLC_00248 2.1e-241 npr 1.11.1.1 C NADH oxidase
MKDMMHLC_00250 3.9e-162 K Transcriptional regulator
MKDMMHLC_00251 1.1e-161 akr5f 1.1.1.346 S reductase
MKDMMHLC_00252 2.8e-165 S Oxidoreductase, aldo keto reductase family protein
MKDMMHLC_00253 8.7e-78 K Winged helix DNA-binding domain
MKDMMHLC_00254 6.4e-268 ycaM E amino acid
MKDMMHLC_00255 3.1e-128 aroD 1.1.1.25, 4.2.1.10 E Type I 3-dehydroquinase
MKDMMHLC_00256 2.7e-32
MKDMMHLC_00257 4.1e-283 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MKDMMHLC_00258 6.2e-149 M Bacterial surface protein 26-residue PARCEL repeat (3 repeats)
MKDMMHLC_00259 0.0 M Bacterial Ig-like domain (group 3)
MKDMMHLC_00260 4.2e-77 fld C Flavodoxin
MKDMMHLC_00261 6.5e-232
MKDMMHLC_00262 3.5e-100 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MKDMMHLC_00263 1.9e-175 pdxB 1.1.1.399, 1.1.1.95 EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
MKDMMHLC_00264 1.4e-151 EG EamA-like transporter family
MKDMMHLC_00265 2.3e-179 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKDMMHLC_00266 9.8e-152 S hydrolase
MKDMMHLC_00267 1.8e-81
MKDMMHLC_00268 6.5e-122 pgm7 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MKDMMHLC_00269 6.8e-141 epsV 2.7.8.12 S glycosyl transferase family 2
MKDMMHLC_00270 9.9e-129 gntR K UTRA
MKDMMHLC_00271 2.3e-48 pts20B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_00272 1.8e-54 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
MKDMMHLC_00273 3.3e-296 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_00274 1.8e-294 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_00275 4.8e-246 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
MKDMMHLC_00276 8.2e-134 V AAA domain, putative AbiEii toxin, Type IV TA system
MKDMMHLC_00277 1.1e-151 V ABC transporter
MKDMMHLC_00278 2.8e-117 K Transcriptional regulator
MKDMMHLC_00279 6.6e-265 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKDMMHLC_00280 3.6e-88 niaR S 3H domain
MKDMMHLC_00281 2.1e-232 S Sterol carrier protein domain
MKDMMHLC_00282 1.4e-211 S Bacterial protein of unknown function (DUF871)
MKDMMHLC_00283 1.2e-35 XK27_01315 S Protein of unknown function (DUF2829)
MKDMMHLC_00284 1.1e-133 IQ Enoyl-(Acyl carrier protein) reductase
MKDMMHLC_00285 7.8e-69 FG Scavenger mRNA decapping enzyme C-term binding
MKDMMHLC_00286 7.5e-103 3.6.1.13 L Belongs to the Nudix hydrolase family
MKDMMHLC_00287 2.5e-110 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MKDMMHLC_00288 4.4e-11 mcbG S Pentapeptide repeats (8 copies)
MKDMMHLC_00289 4.5e-146 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
MKDMMHLC_00290 1.1e-281 thrC 4.2.3.1 E Threonine synthase
MKDMMHLC_00291 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
MKDMMHLC_00293 1.5e-52
MKDMMHLC_00294 5.4e-118
MKDMMHLC_00295 7.3e-86 2.7.7.1, 3.6.1.55 F belongs to the nudix hydrolase family
MKDMMHLC_00296 1.7e-234 malY 4.4.1.8 E Aminotransferase, class I
MKDMMHLC_00298 3.2e-50
MKDMMHLC_00299 1.1e-88
MKDMMHLC_00300 5.5e-71 gtcA S Teichoic acid glycosylation protein
MKDMMHLC_00301 4e-34
MKDMMHLC_00302 1.9e-80 uspA T universal stress protein
MKDMMHLC_00303 5.1e-137
MKDMMHLC_00304 6.9e-164 V ABC transporter, ATP-binding protein
MKDMMHLC_00305 7.9e-61 gntR1 K Transcriptional regulator, GntR family
MKDMMHLC_00306 7.4e-40
MKDMMHLC_00307 0.0 V FtsX-like permease family
MKDMMHLC_00308 1.7e-139 cysA V ABC transporter, ATP-binding protein
MKDMMHLC_00309 1.5e-180 ansA 3.5.1.1 EJ Asparaginase
MKDMMHLC_00310 8.3e-148 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_00311 1.9e-118 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
MKDMMHLC_00312 1.2e-146 ptp3 3.1.3.48 T Tyrosine phosphatase family
MKDMMHLC_00313 3.2e-189 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
MKDMMHLC_00314 1.8e-110 XK27_09620 1.3.5.4 S NADPH-dependent FMN reductase
MKDMMHLC_00315 4.3e-223 XK27_09615 1.3.5.4 S reductase
MKDMMHLC_00316 1.7e-79 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MKDMMHLC_00317 8.7e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MKDMMHLC_00318 2.9e-131 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MKDMMHLC_00319 3.6e-41 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKDMMHLC_00320 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKDMMHLC_00321 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MKDMMHLC_00322 2.1e-279 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MKDMMHLC_00323 1.6e-188 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MKDMMHLC_00324 9.9e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MKDMMHLC_00325 2.3e-287 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MKDMMHLC_00326 2.1e-214 purD 6.3.4.13 F Belongs to the GARS family
MKDMMHLC_00327 1e-122 2.1.1.14 E Methionine synthase
MKDMMHLC_00328 9.2e-253 pgaC GT2 M Glycosyl transferase
MKDMMHLC_00329 2.6e-94
MKDMMHLC_00330 6.5e-156 T EAL domain
MKDMMHLC_00331 5.6e-161 GM NmrA-like family
MKDMMHLC_00332 2.4e-221 pbuG S Permease family
MKDMMHLC_00333 2.7e-236 pbuX F xanthine permease
MKDMMHLC_00334 1e-298 pucR QT Purine catabolism regulatory protein-like family
MKDMMHLC_00335 1.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKDMMHLC_00336 1.6e-171 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MKDMMHLC_00337 6.4e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MKDMMHLC_00338 7.6e-213 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKDMMHLC_00339 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MKDMMHLC_00340 3.3e-169 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MKDMMHLC_00341 1.8e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MKDMMHLC_00342 2.4e-113 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MKDMMHLC_00343 1.6e-169 ydcZ S Putative inner membrane exporter, YdcZ
MKDMMHLC_00344 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MKDMMHLC_00345 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MKDMMHLC_00346 8.2e-96 wecD K Acetyltransferase (GNAT) family
MKDMMHLC_00347 5.6e-115 ylbE GM NAD(P)H-binding
MKDMMHLC_00348 7.3e-161 mleR K LysR family
MKDMMHLC_00349 1.7e-126 S membrane transporter protein
MKDMMHLC_00350 3e-18
MKDMMHLC_00351 7.8e-160 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKDMMHLC_00352 5e-218 patA 2.6.1.1 E Aminotransferase
MKDMMHLC_00353 3.6e-260 gabR K Bacterial regulatory proteins, gntR family
MKDMMHLC_00354 6.3e-295 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MKDMMHLC_00355 8.5e-57 S SdpI/YhfL protein family
MKDMMHLC_00356 1.9e-127 C Zinc-binding dehydrogenase
MKDMMHLC_00357 3e-30 C Zinc-binding dehydrogenase
MKDMMHLC_00358 5e-63 K helix_turn_helix, mercury resistance
MKDMMHLC_00359 2.8e-213 yttB EGP Major facilitator Superfamily
MKDMMHLC_00360 2.9e-269 yjcE P Sodium proton antiporter
MKDMMHLC_00361 4.9e-87 nrdI F Belongs to the NrdI family
MKDMMHLC_00362 1.2e-239 yhdP S Transporter associated domain
MKDMMHLC_00363 4.4e-58
MKDMMHLC_00364 4.1e-74 hspX O Belongs to the small heat shock protein (HSP20) family
MKDMMHLC_00365 7.7e-61
MKDMMHLC_00366 4.2e-92 M1-874 K Domain of unknown function (DUF1836)
MKDMMHLC_00367 5.5e-138 rrp8 K LytTr DNA-binding domain
MKDMMHLC_00368 3.1e-116 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKDMMHLC_00369 1.5e-138
MKDMMHLC_00370 4.5e-91 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MKDMMHLC_00371 2.4e-130 gntR2 K Transcriptional regulator
MKDMMHLC_00372 2.3e-164 S Putative esterase
MKDMMHLC_00373 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MKDMMHLC_00374 2.3e-223 lsgC M Glycosyl transferases group 1
MKDMMHLC_00375 3.3e-21 S Protein of unknown function (DUF2929)
MKDMMHLC_00376 1.7e-48 K Cro/C1-type HTH DNA-binding domain
MKDMMHLC_00377 1.3e-154 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKDMMHLC_00378 1.6e-79 uspA T universal stress protein
MKDMMHLC_00379 0.0 acm2 3.2.1.17 NU Bacterial SH3 domain
MKDMMHLC_00380 5.1e-195 lplA 6.3.1.20 H Lipoate-protein ligase
MKDMMHLC_00381 4e-60
MKDMMHLC_00382 3.7e-73
MKDMMHLC_00383 5e-82 yybC S Protein of unknown function (DUF2798)
MKDMMHLC_00384 1.7e-45
MKDMMHLC_00385 5.2e-47
MKDMMHLC_00386 1.6e-205 metB 2.5.1.48, 4.4.1.8 E Cys/Met metabolism PLP-dependent enzyme
MKDMMHLC_00387 2.3e-56 dsbJ 2.7.1.180, 5.3.4.1 CO Thioredoxin
MKDMMHLC_00388 8.4e-145 yjfP S Dienelactone hydrolase family
MKDMMHLC_00389 9.8e-28
MKDMMHLC_00390 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKDMMHLC_00391 6.5e-47
MKDMMHLC_00392 1.3e-57
MKDMMHLC_00393 2.3e-164
MKDMMHLC_00394 1.3e-72 K Transcriptional regulator
MKDMMHLC_00395 0.0 pepF2 E Oligopeptidase F
MKDMMHLC_00396 3.8e-173 D Alpha beta
MKDMMHLC_00397 1.2e-45 S Enterocin A Immunity
MKDMMHLC_00398 9.5e-65 yvoA_1 K Transcriptional regulator, GntR family
MKDMMHLC_00399 8.7e-125 skfE V ABC transporter
MKDMMHLC_00400 2.7e-132
MKDMMHLC_00401 3.7e-107 pncA Q Isochorismatase family
MKDMMHLC_00402 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MKDMMHLC_00403 0.0 yjcE P Sodium proton antiporter
MKDMMHLC_00404 1.1e-197 yhhX 1.1.1.371 S Oxidoreductase family, C-terminal alpha/beta domain
MKDMMHLC_00405 6e-177 S Oxidoreductase family, NAD-binding Rossmann fold
MKDMMHLC_00406 1.1e-116 K Helix-turn-helix domain, rpiR family
MKDMMHLC_00407 2.3e-157 ccpB 5.1.1.1 K lacI family
MKDMMHLC_00408 8.8e-123 S Sucrose-6F-phosphate phosphohydrolase
MKDMMHLC_00409 2.2e-146 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKDMMHLC_00410 7e-178 iunH2 3.2.2.1 F nucleoside hydrolase
MKDMMHLC_00411 1.2e-97 drgA C Nitroreductase family
MKDMMHLC_00412 3.6e-168 S Polyphosphate kinase 2 (PPK2)
MKDMMHLC_00413 4.4e-143 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_00414 3.4e-183 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
MKDMMHLC_00415 0.0 glpQ 3.1.4.46 C phosphodiesterase
MKDMMHLC_00416 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKDMMHLC_00417 1.5e-74 yjcF S Acetyltransferase (GNAT) domain
MKDMMHLC_00418 3.9e-219 M domain protein
MKDMMHLC_00419 1.5e-41 M domain protein
MKDMMHLC_00420 0.0 ydgH S MMPL family
MKDMMHLC_00421 2.6e-112 S Protein of unknown function (DUF1211)
MKDMMHLC_00422 3.7e-34
MKDMMHLC_00423 5.9e-185 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKDMMHLC_00424 5.2e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MKDMMHLC_00425 8.6e-98 J glyoxalase III activity
MKDMMHLC_00426 1.4e-147 GM Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDMMHLC_00427 5.9e-91 rmeB K transcriptional regulator, MerR family
MKDMMHLC_00428 2.1e-55 S Domain of unknown function (DU1801)
MKDMMHLC_00429 7.6e-166 corA P CorA-like Mg2+ transporter protein
MKDMMHLC_00430 4.6e-216 ysaA V RDD family
MKDMMHLC_00431 3.8e-164 hisK 3.1.3.15 E Histidinol phosphate phosphatase, HisJ
MKDMMHLC_00432 1.9e-214 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MKDMMHLC_00433 4.3e-118 hisG 2.4.2.17 F Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
MKDMMHLC_00434 4.6e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MKDMMHLC_00435 7.9e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
MKDMMHLC_00436 4.1e-110 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MKDMMHLC_00437 2.2e-128 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MKDMMHLC_00438 7.6e-135 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
MKDMMHLC_00439 3.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MKDMMHLC_00440 7.6e-52 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
MKDMMHLC_00441 5.9e-202 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MKDMMHLC_00442 3.1e-85 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MKDMMHLC_00443 3.1e-136 terC P membrane
MKDMMHLC_00444 4.2e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
MKDMMHLC_00445 5.7e-258 npr 1.11.1.1 C NADH oxidase
MKDMMHLC_00446 6.4e-137 XK27_08845 S ABC transporter, ATP-binding protein
MKDMMHLC_00447 8.7e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MKDMMHLC_00448 3.1e-176 XK27_08835 S ABC transporter
MKDMMHLC_00449 1.3e-165 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MKDMMHLC_00450 2.6e-244 metY 2.5.1.49 E Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol
MKDMMHLC_00451 4e-229 hom1 1.1.1.3 E Homoserine dehydrogenase
MKDMMHLC_00452 5e-162 degV S Uncharacterised protein, DegV family COG1307
MKDMMHLC_00453 9.6e-191 panE1 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MKDMMHLC_00454 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MKDMMHLC_00455 6e-39
MKDMMHLC_00456 2.2e-81 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MKDMMHLC_00457 2e-106 3.2.2.20 K acetyltransferase
MKDMMHLC_00458 7.8e-296 S ABC transporter, ATP-binding protein
MKDMMHLC_00459 4e-65 padC Q Phenolic acid decarboxylase
MKDMMHLC_00460 6.7e-142 tesE Q hydratase
MKDMMHLC_00461 2.2e-87 yjaB_1 K Acetyltransferase (GNAT) domain
MKDMMHLC_00462 2.8e-157 degV S DegV family
MKDMMHLC_00463 8.4e-59 2.6.1.2, 2.6.1.66 K Bacteriophage CI repressor helix-turn-helix domain
MKDMMHLC_00464 1.5e-255 pepC 3.4.22.40 E aminopeptidase
MKDMMHLC_00466 1.2e-108 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MKDMMHLC_00467 1.1e-302
MKDMMHLC_00469 3e-158 S Bacterial protein of unknown function (DUF916)
MKDMMHLC_00470 5.9e-92 S Cell surface protein
MKDMMHLC_00471 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MKDMMHLC_00472 4.6e-255 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MKDMMHLC_00473 9.1e-109 jag S R3H domain protein
MKDMMHLC_00474 1.3e-237 Q Imidazolonepropionase and related amidohydrolases
MKDMMHLC_00475 1e-309 E ABC transporter, substratebinding protein
MKDMMHLC_00476 1.8e-105 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MKDMMHLC_00477 6.4e-57 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MKDMMHLC_00478 9.1e-256 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MKDMMHLC_00479 2e-208 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MKDMMHLC_00480 5e-37 yaaA S S4 domain protein YaaA
MKDMMHLC_00481 1.9e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MKDMMHLC_00482 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKDMMHLC_00483 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MKDMMHLC_00484 1.5e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
MKDMMHLC_00485 1e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MKDMMHLC_00486 6.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MKDMMHLC_00487 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MKDMMHLC_00488 1.4e-67 rplI J Binds to the 23S rRNA
MKDMMHLC_00489 7.8e-242 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MKDMMHLC_00490 8.8e-226 yttB EGP Major facilitator Superfamily
MKDMMHLC_00491 3.6e-143 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MKDMMHLC_00492 1.2e-227 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MKDMMHLC_00494 4.2e-276 E ABC transporter, substratebinding protein
MKDMMHLC_00495 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
MKDMMHLC_00496 1.5e-214 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
MKDMMHLC_00497 6.3e-197 glgD 2.4.1.21, 2.7.7.27 GT5 G Nucleotidyl transferase
MKDMMHLC_00498 2e-277 glgA 2.4.1.21 GT5 F Synthesizes alpha-1,4-glucan chains using ADP-glucose
MKDMMHLC_00499 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
MKDMMHLC_00500 0.0 malQ 2.4.1.25, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31,GH77 G Belongs to the glycosyl hydrolase 13 family
MKDMMHLC_00501 4.5e-143 S haloacid dehalogenase-like hydrolase
MKDMMHLC_00502 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MKDMMHLC_00503 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
MKDMMHLC_00504 1.3e-78 S Pyridoxamine 5'-phosphate oxidase
MKDMMHLC_00505 1.6e-31 cspA K Cold shock protein domain
MKDMMHLC_00506 1.7e-37
MKDMMHLC_00508 6.2e-131 K response regulator
MKDMMHLC_00509 0.0 vicK 2.7.13.3 T Histidine kinase
MKDMMHLC_00510 1.2e-244 yycH S YycH protein
MKDMMHLC_00511 2.2e-151 yycI S YycH protein
MKDMMHLC_00512 8.9e-158 vicX 3.1.26.11 S domain protein
MKDMMHLC_00513 6.8e-173 htrA 3.4.21.107 O serine protease
MKDMMHLC_00514 1.2e-82 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MKDMMHLC_00515 1.5e-95 K Bacterial regulatory proteins, tetR family
MKDMMHLC_00516 1.7e-260 calB 1.2.1.68 C Belongs to the aldehyde dehydrogenase family
MKDMMHLC_00517 7.2e-167 L Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
MKDMMHLC_00518 1.8e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
MKDMMHLC_00519 4.2e-32 pnb C nitroreductase
MKDMMHLC_00520 5.7e-67 pnb C nitroreductase
MKDMMHLC_00521 5.2e-65 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
MKDMMHLC_00522 1.8e-116 S Elongation factor G-binding protein, N-terminal
MKDMMHLC_00523 0.0 nqr 1.3.5.4, 1.5.1.36 C FMN_bind
MKDMMHLC_00524 1.3e-257 P Sodium:sulfate symporter transmembrane region
MKDMMHLC_00525 5.7e-158 K LysR family
MKDMMHLC_00526 1e-72 C FMN binding
MKDMMHLC_00527 1.1e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MKDMMHLC_00528 2.3e-164 ptlF S KR domain
MKDMMHLC_00529 6.4e-159 adc 4.1.1.4 Q Acetoacetate decarboxylase (ADC)
MKDMMHLC_00530 1.3e-122 drgA C Nitroreductase family
MKDMMHLC_00531 1.3e-290 QT PucR C-terminal helix-turn-helix domain
MKDMMHLC_00532 2.7e-120 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MKDMMHLC_00533 6.7e-195 pva1 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKDMMHLC_00534 7.4e-250 yjjP S Putative threonine/serine exporter
MKDMMHLC_00535 5.7e-135 wzb 3.1.3.48 T Tyrosine phosphatase family
MKDMMHLC_00536 6.9e-254 1.14.14.9 Q 4-hydroxyphenylacetate
MKDMMHLC_00537 2.9e-81 6.3.3.2 S ASCH
MKDMMHLC_00538 3.2e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
MKDMMHLC_00539 5.5e-172 yobV1 K WYL domain
MKDMMHLC_00540 1.6e-117 azoR C Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKDMMHLC_00541 0.0 tetP J elongation factor G
MKDMMHLC_00542 8.2e-39 S Protein of unknown function
MKDMMHLC_00543 2.1e-61 S Protein of unknown function
MKDMMHLC_00544 8e-152 EG EamA-like transporter family
MKDMMHLC_00545 3.6e-93 MA20_25245 K FR47-like protein
MKDMMHLC_00546 2e-126 hchA S DJ-1/PfpI family
MKDMMHLC_00547 5.4e-181 1.1.1.1 C nadph quinone reductase
MKDMMHLC_00548 9.3e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_00549 2.3e-235 mepA V MATE efflux family protein
MKDMMHLC_00550 2.2e-167 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
MKDMMHLC_00551 1.6e-140 S Belongs to the UPF0246 family
MKDMMHLC_00552 6e-76
MKDMMHLC_00553 3.2e-308 oppA E Bacterial extracellular solute-binding proteins, family 5 Middle
MKDMMHLC_00554 7e-141
MKDMMHLC_00556 2.3e-142 2.7.7.47 H Mediates bacterial resistance to the antibiotics streptomycin and spectomycin
MKDMMHLC_00557 4.8e-40
MKDMMHLC_00558 7.8e-129 cbiO P ABC transporter
MKDMMHLC_00559 2.6e-149 P Cobalt transport protein
MKDMMHLC_00560 4.8e-182 nikMN P PDGLE domain
MKDMMHLC_00561 2.1e-120 K Crp-like helix-turn-helix domain
MKDMMHLC_00562 1e-240 larA 5.1.2.1 S Domain of unknown function (DUF2088)
MKDMMHLC_00563 5.9e-124 larB S AIR carboxylase
MKDMMHLC_00564 8.5e-131 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
MKDMMHLC_00565 1.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_00566 6.3e-151 larE S NAD synthase
MKDMMHLC_00567 5.5e-178 1.6.5.5 C Zinc-binding dehydrogenase
MKDMMHLC_00569 1.3e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MKDMMHLC_00570 5.3e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MKDMMHLC_00571 1.3e-111 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MKDMMHLC_00572 9.9e-206 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MKDMMHLC_00573 4.3e-135 S peptidase C26
MKDMMHLC_00574 9.8e-302 L HIRAN domain
MKDMMHLC_00575 3.4e-85 F NUDIX domain
MKDMMHLC_00576 2.6e-250 yifK E Amino acid permease
MKDMMHLC_00577 5.2e-122
MKDMMHLC_00578 3.3e-149 ydjP I Alpha/beta hydrolase family
MKDMMHLC_00579 0.0 pacL1 P P-type ATPase
MKDMMHLC_00580 2.9e-142 2.4.2.3 F Phosphorylase superfamily
MKDMMHLC_00581 1.6e-28 KT PspC domain
MKDMMHLC_00582 3.6e-111 S NADPH-dependent FMN reductase
MKDMMHLC_00583 1.2e-74 papX3 K Transcriptional regulator
MKDMMHLC_00584 4.6e-73 hsp1 O Belongs to the small heat shock protein (HSP20) family
MKDMMHLC_00585 5.8e-82 S Protein of unknown function (DUF3021)
MKDMMHLC_00586 4.7e-227 mdtG EGP Major facilitator Superfamily
MKDMMHLC_00587 5e-51 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_00588 8.1e-216 yeaN P Transporter, major facilitator family protein
MKDMMHLC_00590 3.4e-160 S reductase
MKDMMHLC_00591 1.2e-165 1.1.1.65 C Aldo keto reductase
MKDMMHLC_00592 4.5e-82 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase like
MKDMMHLC_00593 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
MKDMMHLC_00594 7.8e-49
MKDMMHLC_00595 2.2e-258
MKDMMHLC_00596 4e-209 C Oxidoreductase
MKDMMHLC_00597 4.9e-151 cbiQ P cobalt transport
MKDMMHLC_00598 0.0 ykoD P ABC transporter, ATP-binding protein
MKDMMHLC_00599 2.5e-98 S UPF0397 protein
MKDMMHLC_00601 1.6e-129 K UbiC transcription regulator-associated domain protein
MKDMMHLC_00602 8.3e-54 K Transcriptional regulator PadR-like family
MKDMMHLC_00603 3e-134
MKDMMHLC_00604 5.8e-149
MKDMMHLC_00605 9.1e-89
MKDMMHLC_00606 1.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
MKDMMHLC_00607 2e-169 yjjC V ABC transporter
MKDMMHLC_00608 4.3e-297 M Exporter of polyketide antibiotics
MKDMMHLC_00609 1.1e-116 K Transcriptional regulator
MKDMMHLC_00610 1.8e-276 C Electron transfer flavoprotein FAD-binding domain
MKDMMHLC_00611 9.5e-73 folT 2.7.13.3 T ECF transporter, substrate-specific component
MKDMMHLC_00613 1.9e-92 K Bacterial regulatory proteins, tetR family
MKDMMHLC_00614 2.2e-190 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MKDMMHLC_00615 8e-185 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dak1 domain
MKDMMHLC_00616 5.5e-101 dhaL 2.7.1.121 S Dak2
MKDMMHLC_00617 9e-57 dhaM 2.7.1.121 S PTS system fructose IIA component
MKDMMHLC_00618 7.3e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_00619 1e-190 malR K Transcriptional regulator, LacI family
MKDMMHLC_00620 2e-180 yvdE K helix_turn _helix lactose operon repressor
MKDMMHLC_00621 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
MKDMMHLC_00622 7.5e-49 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_00624 4.7e-214 S membrane
MKDMMHLC_00625 9.2e-82 K Bacterial regulatory proteins, tetR family
MKDMMHLC_00626 0.0 CP_1020 S Zinc finger, swim domain protein
MKDMMHLC_00627 2e-112 GM epimerase
MKDMMHLC_00628 4.1e-68 S Protein of unknown function (DUF1722)
MKDMMHLC_00629 9.1e-71 yneH 1.20.4.1 P ArsC family
MKDMMHLC_00630 1.2e-106 yjhB 3.6.1.13, 3.6.1.55 F NUDIX domain
MKDMMHLC_00631 8e-137 K DeoR C terminal sensor domain
MKDMMHLC_00632 0.0 naoX P Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKDMMHLC_00633 9.2e-209 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKDMMHLC_00634 4.3e-77 K Transcriptional regulator
MKDMMHLC_00635 2.2e-241 EGP Major facilitator Superfamily
MKDMMHLC_00636 2.6e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKDMMHLC_00637 0.0 3.6.3.6 P Cation transporter/ATPase, N-terminus
MKDMMHLC_00638 2.2e-179 C Zinc-binding dehydrogenase
MKDMMHLC_00639 1.5e-216 I transferase activity, transferring acyl groups other than amino-acyl groups
MKDMMHLC_00640 1.7e-207
MKDMMHLC_00641 8.1e-91 yetL K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_00642 7.8e-61 P Rhodanese Homology Domain
MKDMMHLC_00643 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
MKDMMHLC_00644 3.1e-84 K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_00645 3.2e-167 drrA V ABC transporter
MKDMMHLC_00646 2e-119 drrB U ABC-2 type transporter
MKDMMHLC_00647 6.9e-223 M O-Antigen ligase
MKDMMHLC_00648 1e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
MKDMMHLC_00649 7.2e-197 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MKDMMHLC_00650 1.5e-233 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MKDMMHLC_00651 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKDMMHLC_00653 5.6e-29 S Protein of unknown function (DUF2929)
MKDMMHLC_00654 0.0 dnaE 2.7.7.7 L DNA polymerase
MKDMMHLC_00655 1.5e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
MKDMMHLC_00656 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MKDMMHLC_00657 1.5e-74 yeaL S Protein of unknown function (DUF441)
MKDMMHLC_00658 1.1e-169 cvfB S S1 domain
MKDMMHLC_00659 1.1e-164 xerD D recombinase XerD
MKDMMHLC_00660 4.8e-69 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MKDMMHLC_00661 5.7e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MKDMMHLC_00662 7.9e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MKDMMHLC_00663 1.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKDMMHLC_00664 1.1e-96 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MKDMMHLC_00665 3.6e-196 ypbB 5.1.3.1 S Helix-turn-helix domain
MKDMMHLC_00666 6.2e-271 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MKDMMHLC_00667 2e-19 M Lysin motif
MKDMMHLC_00668 3.8e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MKDMMHLC_00669 1.8e-213 rpsA 1.17.7.4 J Ribosomal protein S1
MKDMMHLC_00670 1e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MKDMMHLC_00671 1.1e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MKDMMHLC_00672 2.1e-206 S Tetratricopeptide repeat protein
MKDMMHLC_00673 3.3e-149 3.1.3.102, 3.1.3.104 S hydrolase
MKDMMHLC_00674 5.4e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MKDMMHLC_00675 2.1e-227 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MKDMMHLC_00676 9.6e-85
MKDMMHLC_00677 0.0 yfmR S ABC transporter, ATP-binding protein
MKDMMHLC_00678 1.1e-188 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MKDMMHLC_00679 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MKDMMHLC_00680 5.1e-148 DegV S EDD domain protein, DegV family
MKDMMHLC_00681 2.1e-150 ypmR E GDSL-like Lipase/Acylhydrolase
MKDMMHLC_00682 3.1e-113 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MKDMMHLC_00683 3.4e-35 yozE S Belongs to the UPF0346 family
MKDMMHLC_00684 1.2e-261 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
MKDMMHLC_00685 7.3e-251 emrY EGP Major facilitator Superfamily
MKDMMHLC_00686 1.5e-197 XK27_00915 C Luciferase-like monooxygenase
MKDMMHLC_00687 4.2e-124 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MKDMMHLC_00688 2.3e-173 L restriction endonuclease
MKDMMHLC_00689 3.1e-170 cpsY K Transcriptional regulator, LysR family
MKDMMHLC_00690 6.8e-228 XK27_05470 E Methionine synthase
MKDMMHLC_00692 4.8e-162 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MKDMMHLC_00693 8.2e-137 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MKDMMHLC_00694 9.5e-158 dprA LU DNA protecting protein DprA
MKDMMHLC_00695 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MKDMMHLC_00696 6.6e-251 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
MKDMMHLC_00697 1.5e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
MKDMMHLC_00698 6.7e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MKDMMHLC_00699 8.6e-257 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MKDMMHLC_00700 3.8e-170 lacX 5.1.3.3 G Aldose 1-epimerase
MKDMMHLC_00701 5.2e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MKDMMHLC_00702 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKDMMHLC_00703 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MKDMMHLC_00704 5.9e-177 K Transcriptional regulator
MKDMMHLC_00705 2.9e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
MKDMMHLC_00706 4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MKDMMHLC_00707 1e-95 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKDMMHLC_00708 4.2e-32 S YozE SAM-like fold
MKDMMHLC_00709 1.2e-157 xerD L Phage integrase, N-terminal SAM-like domain
MKDMMHLC_00710 3e-276 GT89 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKDMMHLC_00711 6.3e-246 M Glycosyl transferase family group 2
MKDMMHLC_00712 1.8e-66
MKDMMHLC_00713 9.3e-253 gshR1 1.8.1.7 C Glutathione reductase
MKDMMHLC_00714 7.8e-76 mgrA K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_00715 5.3e-95 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
MKDMMHLC_00716 0.0 tarL 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKDMMHLC_00717 9.9e-216 tarK 2.7.8.14, 2.7.8.47 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKDMMHLC_00718 9.7e-194 tarJ 1.1.1.137, 1.1.1.303, 1.1.1.4, 1.1.1.405 E Catalyzes the NADPH dependent reduction of D-ribulose 5- phosphate to D-ribitol 5-phosphate
MKDMMHLC_00719 3.3e-118 ispD 1.1.1.405, 2.7.7.40, 2.7.7.60, 4.6.1.12 I Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate
MKDMMHLC_00720 5.1e-227
MKDMMHLC_00721 4.6e-275 lldP C L-lactate permease
MKDMMHLC_00722 4.1e-59
MKDMMHLC_00723 3.5e-123
MKDMMHLC_00724 3.2e-245 cycA E Amino acid permease
MKDMMHLC_00725 3.7e-130 XK27_00890 S Domain of unknown function (DUF368)
MKDMMHLC_00726 4.6e-129 yejC S Protein of unknown function (DUF1003)
MKDMMHLC_00727 6.2e-51 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
MKDMMHLC_00728 4.6e-12
MKDMMHLC_00729 1.6e-211 pmrB EGP Major facilitator Superfamily
MKDMMHLC_00730 3.3e-149 2.7.7.12 C Domain of unknown function (DUF4931)
MKDMMHLC_00731 1.4e-49
MKDMMHLC_00732 1.6e-09
MKDMMHLC_00733 2.9e-131 S Protein of unknown function (DUF975)
MKDMMHLC_00734 8.3e-78 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MKDMMHLC_00735 2.1e-160 degV S EDD domain protein, DegV family
MKDMMHLC_00736 1.9e-66 K Transcriptional regulator
MKDMMHLC_00737 0.0 FbpA K Fibronectin-binding protein
MKDMMHLC_00738 9.3e-133 S ABC-2 family transporter protein
MKDMMHLC_00739 5.4e-164 V ABC transporter, ATP-binding protein
MKDMMHLC_00740 3e-92 3.6.1.55 F NUDIX domain
MKDMMHLC_00741 2.9e-136 S Uncharacterized protein conserved in bacteria (DUF2087)
MKDMMHLC_00742 1.2e-69 S LuxR family transcriptional regulator
MKDMMHLC_00743 1.7e-130 cat 2.3.1.28 V Chloramphenicol acetyltransferase
MKDMMHLC_00746 3.1e-71 frataxin S Domain of unknown function (DU1801)
MKDMMHLC_00747 5.5e-112 pgm5 G Phosphoglycerate mutase family
MKDMMHLC_00748 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MKDMMHLC_00749 8.1e-207 carA 6.3.5.5 F Belongs to the CarA family
MKDMMHLC_00750 3.3e-89 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MKDMMHLC_00751 2e-174 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MKDMMHLC_00752 4.4e-74 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MKDMMHLC_00753 1.1e-292 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MKDMMHLC_00754 2.2e-61 esbA S Family of unknown function (DUF5322)
MKDMMHLC_00755 2.2e-66 rnhA 3.1.26.4 L Ribonuclease HI
MKDMMHLC_00756 9.5e-211 yurR 1.4.5.1 E FAD dependent oxidoreductase
MKDMMHLC_00757 5.9e-146 S hydrolase activity, acting on ester bonds
MKDMMHLC_00758 2.3e-193
MKDMMHLC_00759 3.3e-121 3.6.3.35 P ATPases associated with a variety of cellular activities
MKDMMHLC_00760 1.3e-123
MKDMMHLC_00761 2.3e-181 mccF 3.4.17.13 V LD-carboxypeptidase
MKDMMHLC_00762 2.6e-239 M hydrolase, family 25
MKDMMHLC_00763 9.2e-92 zmp2 O Zinc-dependent metalloprotease
MKDMMHLC_00764 7.3e-258 pepC 3.4.22.40 E Peptidase C1-like family
MKDMMHLC_00765 3.2e-124 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MKDMMHLC_00766 1.2e-51 HA62_12640 S GCN5-related N-acetyl-transferase
MKDMMHLC_00767 3.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MKDMMHLC_00768 1.3e-257 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MKDMMHLC_00769 3.7e-205 yacL S domain protein
MKDMMHLC_00770 2.6e-288 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MKDMMHLC_00771 2.3e-270 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKDMMHLC_00772 3.5e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MKDMMHLC_00773 3.3e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MKDMMHLC_00774 7.7e-97 yacP S YacP-like NYN domain
MKDMMHLC_00775 2.4e-101 sigH K Sigma-70 region 2
MKDMMHLC_00776 6.5e-22 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MKDMMHLC_00777 6.8e-29 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MKDMMHLC_00778 3.7e-99 nusG K Participates in transcription elongation, termination and antitermination
MKDMMHLC_00779 2.6e-158 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_00780 2.4e-69 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MKDMMHLC_00781 5.1e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MKDMMHLC_00782 4.6e-80 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MKDMMHLC_00783 9.9e-56 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MKDMMHLC_00784 9.3e-178 F DNA/RNA non-specific endonuclease
MKDMMHLC_00785 1.2e-38 L nuclease
MKDMMHLC_00786 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKDMMHLC_00787 4.6e-108 yvdD 3.2.2.10 S Belongs to the LOG family
MKDMMHLC_00788 2.2e-198 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKDMMHLC_00789 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MKDMMHLC_00790 6.5e-37 nrdH O Glutaredoxin
MKDMMHLC_00791 3.4e-109 rsmC 2.1.1.172 J Methyltransferase
MKDMMHLC_00792 5.9e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MKDMMHLC_00793 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKDMMHLC_00794 1.7e-40 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MKDMMHLC_00795 7.4e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MKDMMHLC_00796 2.2e-38 yaaL S Protein of unknown function (DUF2508)
MKDMMHLC_00797 3.3e-118 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MKDMMHLC_00798 2.4e-53 yaaQ S Cyclic-di-AMP receptor
MKDMMHLC_00799 3.3e-186 holB 2.7.7.7 L DNA polymerase III
MKDMMHLC_00800 1e-57 yabA L Involved in initiation control of chromosome replication
MKDMMHLC_00801 1.1e-164 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MKDMMHLC_00802 1.1e-147 fat 3.1.2.21 I Acyl-ACP thioesterase
MKDMMHLC_00803 4e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MKDMMHLC_00804 7.2e-211 phnW 2.5.1.49, 2.6.1.37, 3.11.1.1 E Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily
MKDMMHLC_00805 8.5e-145 phnX 2.6.1.37, 3.1.3.18, 3.11.1.1 E Belongs to the HAD-like hydrolase superfamily. PhnX family
MKDMMHLC_00806 2.6e-144 phnE1 3.6.1.63 U ABC transporter permease
MKDMMHLC_00807 2.5e-136 phnE 3.6.1.63 U Phosphonate ABC transporter permease
MKDMMHLC_00808 2.8e-137 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MKDMMHLC_00809 5.1e-190 phnD P Phosphonate ABC transporter
MKDMMHLC_00810 1.7e-128 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MKDMMHLC_00811 6.7e-101 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MKDMMHLC_00812 1e-81 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
MKDMMHLC_00813 1.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MKDMMHLC_00814 3.3e-307 uup S ABC transporter, ATP-binding protein
MKDMMHLC_00815 1.4e-119 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MKDMMHLC_00816 6.1e-109 ydiL S CAAX protease self-immunity
MKDMMHLC_00817 1e-31 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MKDMMHLC_00818 8.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MKDMMHLC_00819 0.0 ydaO E amino acid
MKDMMHLC_00820 2.7e-181 tagO 2.7.8.33, 2.7.8.35 M transferase
MKDMMHLC_00821 4.3e-145 pstS P Phosphate
MKDMMHLC_00822 1.7e-114 yvyE 3.4.13.9 S YigZ family
MKDMMHLC_00823 9.6e-258 comFA L Helicase C-terminal domain protein
MKDMMHLC_00824 7.5e-126 comFC S Competence protein
MKDMMHLC_00825 3.5e-100 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MKDMMHLC_00826 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MKDMMHLC_00827 4.1e-203 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MKDMMHLC_00828 7.9e-216 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
MKDMMHLC_00829 1.5e-132 K response regulator
MKDMMHLC_00830 3.5e-250 phoR 2.7.13.3 T Histidine kinase
MKDMMHLC_00831 2.1e-149 pstS P Phosphate
MKDMMHLC_00832 2.6e-161 pstC P probably responsible for the translocation of the substrate across the membrane
MKDMMHLC_00833 1.5e-155 pstA P Phosphate transport system permease protein PstA
MKDMMHLC_00834 1.1e-147 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKDMMHLC_00835 3.3e-138 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MKDMMHLC_00836 8.3e-117 phoU P Plays a role in the regulation of phosphate uptake
MKDMMHLC_00837 2e-49 pspC KT positive regulation of macromolecule biosynthetic process
MKDMMHLC_00838 9.2e-54 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MKDMMHLC_00839 1.4e-176 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MKDMMHLC_00840 2.3e-164 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MKDMMHLC_00841 8.5e-182 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MKDMMHLC_00842 2.1e-171 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MKDMMHLC_00843 1.9e-124 yliE T Putative diguanylate phosphodiesterase
MKDMMHLC_00844 3.9e-270 nox C NADH oxidase
MKDMMHLC_00845 1.7e-176 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MKDMMHLC_00846 2e-109 yviA S Protein of unknown function (DUF421)
MKDMMHLC_00847 1.1e-61 S Protein of unknown function (DUF3290)
MKDMMHLC_00848 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MKDMMHLC_00849 3.3e-132 yliE T Putative diguanylate phosphodiesterase
MKDMMHLC_00850 1.4e-259 nox S Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKDMMHLC_00851 3.3e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MKDMMHLC_00852 9.2e-212 norA EGP Major facilitator Superfamily
MKDMMHLC_00853 3.6e-117 yfbR S HD containing hydrolase-like enzyme
MKDMMHLC_00854 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MKDMMHLC_00855 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MKDMMHLC_00856 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MKDMMHLC_00857 1.8e-231 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MKDMMHLC_00858 7.9e-263 argH 4.3.2.1 E argininosuccinate lyase
MKDMMHLC_00859 3.5e-86 S Short repeat of unknown function (DUF308)
MKDMMHLC_00860 1.1e-161 rapZ S Displays ATPase and GTPase activities
MKDMMHLC_00861 1.9e-189 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MKDMMHLC_00862 3.7e-168 whiA K May be required for sporulation
MKDMMHLC_00863 9.9e-289 oppA E ABC transporter, substratebinding protein
MKDMMHLC_00864 7.4e-175 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKDMMHLC_00865 3e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MKDMMHLC_00867 4.2e-245 rpoN K Sigma-54 factor, core binding domain
MKDMMHLC_00868 7.3e-189 cggR K Putative sugar-binding domain
MKDMMHLC_00869 2.6e-191 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MKDMMHLC_00870 8.1e-224 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MKDMMHLC_00871 1.2e-137 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MKDMMHLC_00872 1.6e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MKDMMHLC_00873 2e-131
MKDMMHLC_00874 6.6e-295 clcA P chloride
MKDMMHLC_00875 3.5e-30 secG U Preprotein translocase
MKDMMHLC_00876 5e-139 est 3.1.1.1 S Serine aminopeptidase, S33
MKDMMHLC_00877 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MKDMMHLC_00878 9.3e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MKDMMHLC_00879 0.0 3.4.21.72 M Bacterial Ig-like domain (group 3)
MKDMMHLC_00880 1.5e-256 glnP P ABC transporter
MKDMMHLC_00881 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_00882 6.1e-105 yxjI
MKDMMHLC_00883 4.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
MKDMMHLC_00884 1.6e-136 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MKDMMHLC_00885 1.4e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MKDMMHLC_00886 5e-81 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MKDMMHLC_00887 8.1e-88 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
MKDMMHLC_00888 5.6e-100 dnaQ 2.7.7.7 L DNA polymerase III
MKDMMHLC_00889 5.6e-154 xth 3.1.11.2 L exodeoxyribonuclease III
MKDMMHLC_00890 3.9e-162 yceM 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
MKDMMHLC_00891 6.2e-168 murB 1.3.1.98 M Cell wall formation
MKDMMHLC_00892 0.0 yjcE P Sodium proton antiporter
MKDMMHLC_00893 1.3e-90 K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_00894 2.1e-120 S Protein of unknown function (DUF1361)
MKDMMHLC_00895 6e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MKDMMHLC_00896 1.6e-129 ybbR S YbbR-like protein
MKDMMHLC_00897 1.6e-252 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MKDMMHLC_00898 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MKDMMHLC_00899 3e-232 pyrP F Permease
MKDMMHLC_00900 6.5e-128 atpB C it plays a direct role in the translocation of protons across the membrane
MKDMMHLC_00901 2.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKDMMHLC_00902 6e-51 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MKDMMHLC_00903 1.8e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MKDMMHLC_00904 2.7e-280 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MKDMMHLC_00905 2.3e-165 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MKDMMHLC_00906 2.1e-263 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MKDMMHLC_00907 1.1e-50 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MKDMMHLC_00908 3.7e-246 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKDMMHLC_00909 2.1e-102 J Acetyltransferase (GNAT) domain
MKDMMHLC_00910 2.7e-180 mbl D Cell shape determining protein MreB Mrl
MKDMMHLC_00911 2.3e-43 yidD S Could be involved in insertion of integral membrane proteins into the membrane
MKDMMHLC_00912 1.2e-32 S Protein of unknown function (DUF2969)
MKDMMHLC_00913 9.3e-220 rodA D Belongs to the SEDS family
MKDMMHLC_00914 3.6e-48 gcsH2 E glycine cleavage
MKDMMHLC_00915 4e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MKDMMHLC_00916 1.4e-111 metI U ABC transporter permease
MKDMMHLC_00917 6.5e-148 metQ M Belongs to the nlpA lipoprotein family
MKDMMHLC_00918 2.8e-168 hicD1 1.1.1.27 C Belongs to the LDH MDH superfamily
MKDMMHLC_00919 1.6e-177 S Protein of unknown function (DUF2785)
MKDMMHLC_00920 3.6e-188 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MKDMMHLC_00921 5.4e-214 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MKDMMHLC_00922 7.1e-297 glpQ3 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
MKDMMHLC_00923 3.3e-161 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_00924 6.3e-202 bla2 3.5.2.6 V Beta-lactamase enzyme family
MKDMMHLC_00925 6.2e-82 usp6 T universal stress protein
MKDMMHLC_00926 1.5e-38
MKDMMHLC_00927 8e-238 rarA L recombination factor protein RarA
MKDMMHLC_00928 0.0 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MKDMMHLC_00929 1.9e-43 czrA K Helix-turn-helix domain
MKDMMHLC_00930 2.2e-108 S Protein of unknown function (DUF1648)
MKDMMHLC_00931 7.3e-80 yueI S Protein of unknown function (DUF1694)
MKDMMHLC_00932 5.2e-113 yktB S Belongs to the UPF0637 family
MKDMMHLC_00933 3.1e-107 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MKDMMHLC_00934 5e-81 ytsP 1.8.4.14 T GAF domain-containing protein
MKDMMHLC_00935 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MKDMMHLC_00936 8.3e-218 iscS2 2.8.1.7 E Aminotransferase class V
MKDMMHLC_00937 1.6e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MKDMMHLC_00938 1.2e-233 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MKDMMHLC_00939 3e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MKDMMHLC_00940 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MKDMMHLC_00941 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MKDMMHLC_00942 1.3e-116 radC L DNA repair protein
MKDMMHLC_00943 2.8e-161 mreB D cell shape determining protein MreB
MKDMMHLC_00944 2.6e-144 mreC M Involved in formation and maintenance of cell shape
MKDMMHLC_00945 1.2e-88 mreD M rod shape-determining protein MreD
MKDMMHLC_00946 1.1e-116 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
MKDMMHLC_00947 1.2e-146 minD D Belongs to the ParA family
MKDMMHLC_00948 4.6e-109 glnP P ABC transporter permease
MKDMMHLC_00949 2.5e-115 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_00950 1.5e-155 aatB ET ABC transporter substrate-binding protein
MKDMMHLC_00951 3.8e-254 lysC 2.7.2.4 E Belongs to the aspartokinase family
MKDMMHLC_00952 1.9e-231 ymfF S Peptidase M16 inactive domain protein
MKDMMHLC_00953 2.9e-251 ymfH S Peptidase M16
MKDMMHLC_00954 5.7e-110 ymfM S Helix-turn-helix domain
MKDMMHLC_00955 3.7e-97 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MKDMMHLC_00956 2.5e-231 cinA 3.5.1.42 S Belongs to the CinA family
MKDMMHLC_00957 5e-191 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MKDMMHLC_00958 2.1e-216 rny S Endoribonuclease that initiates mRNA decay
MKDMMHLC_00959 2.7e-154 ymdB S YmdB-like protein
MKDMMHLC_00960 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MKDMMHLC_00961 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MKDMMHLC_00962 3.1e-71
MKDMMHLC_00963 0.0 S Bacterial membrane protein YfhO
MKDMMHLC_00964 9.6e-89
MKDMMHLC_00965 4.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MKDMMHLC_00966 2.1e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MKDMMHLC_00967 6.3e-201 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MKDMMHLC_00968 3.3e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MKDMMHLC_00969 2.8e-29 yajC U Preprotein translocase
MKDMMHLC_00970 5.3e-217 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MKDMMHLC_00971 7e-178 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MKDMMHLC_00972 9.3e-245 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MKDMMHLC_00973 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MKDMMHLC_00974 2.4e-43 yrzL S Belongs to the UPF0297 family
MKDMMHLC_00975 7.3e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MKDMMHLC_00976 1.6e-48 yrzB S Belongs to the UPF0473 family
MKDMMHLC_00977 2.7e-36 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
MKDMMHLC_00978 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MKDMMHLC_00979 3.3e-52 trxA O Belongs to the thioredoxin family
MKDMMHLC_00980 7.6e-126 yslB S Protein of unknown function (DUF2507)
MKDMMHLC_00981 9e-150 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MKDMMHLC_00982 1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MKDMMHLC_00983 9.5e-97 S Phosphoesterase
MKDMMHLC_00984 6.5e-87 ykuL S (CBS) domain
MKDMMHLC_00985 2.6e-76 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MKDMMHLC_00986 1.7e-226 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MKDMMHLC_00987 2.6e-158 ykuT M mechanosensitive ion channel
MKDMMHLC_00988 1.9e-23 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MKDMMHLC_00989 2.8e-56
MKDMMHLC_00990 1.9e-62 K helix_turn_helix, mercury resistance
MKDMMHLC_00991 2.4e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MKDMMHLC_00992 1.9e-181 ccpA K catabolite control protein A
MKDMMHLC_00993 6.8e-164 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MKDMMHLC_00994 1.6e-49 S DsrE/DsrF-like family
MKDMMHLC_00995 8.3e-131 yebC K Transcriptional regulatory protein
MKDMMHLC_00996 4.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKDMMHLC_00997 2.1e-174 comGA NU Type II IV secretion system protein
MKDMMHLC_00998 1.9e-189 comGB NU type II secretion system
MKDMMHLC_00999 5.5e-43 comGC U competence protein ComGC
MKDMMHLC_01000 3.2e-83 gspG NU general secretion pathway protein
MKDMMHLC_01001 8.6e-20
MKDMMHLC_01002 4.5e-88 S Prokaryotic N-terminal methylation motif
MKDMMHLC_01004 4e-185 ytxK 2.1.1.72 L N-6 DNA Methylase
MKDMMHLC_01005 7e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKDMMHLC_01006 5.3e-251 cycA E Amino acid permease
MKDMMHLC_01007 4.4e-117 S Calcineurin-like phosphoesterase
MKDMMHLC_01008 1.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
MKDMMHLC_01009 1.5e-80 yutD S Protein of unknown function (DUF1027)
MKDMMHLC_01010 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MKDMMHLC_01011 1.8e-116 S Protein of unknown function (DUF1461)
MKDMMHLC_01012 1.9e-118 dedA S SNARE-like domain protein
MKDMMHLC_01013 5.5e-109 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MKDMMHLC_01014 1.6e-75 yugI 5.3.1.9 J general stress protein
MKDMMHLC_01015 3.4e-112 ppaX_1 3.1.3.18, 3.6.1.1 S haloacid dehalogenase-like hydrolase
MKDMMHLC_01016 1.5e-80 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MKDMMHLC_01017 1.3e-128 K Helix-turn-helix domain, rpiR family
MKDMMHLC_01018 8.5e-159 S Alpha beta hydrolase
MKDMMHLC_01019 9.9e-112 GM NmrA-like family
MKDMMHLC_01020 4.9e-78 S Uncharacterized protein conserved in bacteria (DUF2255)
MKDMMHLC_01021 1.9e-161 K Transcriptional regulator
MKDMMHLC_01022 1.9e-172 C nadph quinone reductase
MKDMMHLC_01023 6.3e-14 S Alpha beta hydrolase
MKDMMHLC_01024 2.1e-271 nox C Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain
MKDMMHLC_01025 4e-102 desR K helix_turn_helix, Lux Regulon
MKDMMHLC_01026 2.8e-207 desK 2.7.13.3 T Histidine kinase
MKDMMHLC_01027 3.1e-136 yvfS V ABC-2 type transporter
MKDMMHLC_01028 5.2e-159 yvfR V ABC transporter
MKDMMHLC_01030 6e-82 K Acetyltransferase (GNAT) domain
MKDMMHLC_01031 2.4e-72 K MarR family
MKDMMHLC_01032 3.8e-114 S Psort location CytoplasmicMembrane, score
MKDMMHLC_01033 2.6e-12 yjdF S Protein of unknown function (DUF2992)
MKDMMHLC_01034 5.6e-161 V ABC transporter, ATP-binding protein
MKDMMHLC_01035 5.2e-128 S ABC-2 family transporter protein
MKDMMHLC_01036 1.5e-197
MKDMMHLC_01037 5.9e-202
MKDMMHLC_01038 4.8e-165 ytrB V ABC transporter, ATP-binding protein
MKDMMHLC_01039 9.5e-65 K helix_turn_helix gluconate operon transcriptional repressor
MKDMMHLC_01040 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MKDMMHLC_01041 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MKDMMHLC_01042 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MKDMMHLC_01043 6.8e-175 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MKDMMHLC_01044 3.1e-147 recO L Involved in DNA repair and RecF pathway recombination
MKDMMHLC_01045 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MKDMMHLC_01046 4.5e-73 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MKDMMHLC_01047 1.9e-83 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MKDMMHLC_01048 3.4e-180 phoH T phosphate starvation-inducible protein PhoH
MKDMMHLC_01049 2.6e-71 yqeY S YqeY-like protein
MKDMMHLC_01050 9.7e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MKDMMHLC_01051 2.1e-151 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
MKDMMHLC_01052 7.7e-109 C Enoyl-(Acyl carrier protein) reductase
MKDMMHLC_01053 1.9e-169 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MKDMMHLC_01054 6.6e-223 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKDMMHLC_01055 1.7e-159 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
MKDMMHLC_01056 3.2e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKDMMHLC_01057 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MKDMMHLC_01058 2.2e-243 hisS 6.1.1.21 J histidyl-tRNA synthetase
MKDMMHLC_01059 4.3e-155 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
MKDMMHLC_01060 1.6e-160 yniA G Fructosamine kinase
MKDMMHLC_01061 6.5e-116 3.1.3.18 J HAD-hyrolase-like
MKDMMHLC_01062 8.5e-78 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MKDMMHLC_01063 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MKDMMHLC_01064 9.6e-58
MKDMMHLC_01065 2.9e-134 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MKDMMHLC_01066 4.5e-177 prmA J Ribosomal protein L11 methyltransferase
MKDMMHLC_01067 4e-113 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MKDMMHLC_01068 1.4e-49
MKDMMHLC_01069 1.4e-49
MKDMMHLC_01072 4e-127 3.6.4.12 L Belongs to the 'phage' integrase family
MKDMMHLC_01073 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKDMMHLC_01074 6.1e-246 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MKDMMHLC_01075 2.4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKDMMHLC_01076 2.5e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MKDMMHLC_01077 7e-297 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKDMMHLC_01078 8.8e-19 dltX S D-Ala-teichoic acid biosynthesis protein
MKDMMHLC_01079 4.4e-198 pbpX2 V Beta-lactamase
MKDMMHLC_01080 1.2e-184 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MKDMMHLC_01081 0.0 dnaK O Heat shock 70 kDa protein
MKDMMHLC_01082 1.5e-80 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MKDMMHLC_01083 2.4e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MKDMMHLC_01084 7.3e-132 budA 4.1.1.5 Q Alpha-acetolactate decarboxylase
MKDMMHLC_01085 1.7e-187 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MKDMMHLC_01086 1.2e-171 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MKDMMHLC_01087 2e-86 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MKDMMHLC_01088 5.5e-195 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
MKDMMHLC_01089 2.5e-223 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
MKDMMHLC_01090 8.5e-93
MKDMMHLC_01091 1e-215 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MKDMMHLC_01092 2e-264 ydiN 5.4.99.5 G Major Facilitator
MKDMMHLC_01093 4.6e-50 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MKDMMHLC_01094 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MKDMMHLC_01095 3.1e-47 ylxQ J ribosomal protein
MKDMMHLC_01096 9.5e-49 ylxR K Protein of unknown function (DUF448)
MKDMMHLC_01097 3.3e-217 nusA K Participates in both transcription termination and antitermination
MKDMMHLC_01098 4.2e-83 rimP J Required for maturation of 30S ribosomal subunits
MKDMMHLC_01099 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MKDMMHLC_01100 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MKDMMHLC_01101 9.5e-231 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MKDMMHLC_01102 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MKDMMHLC_01103 1.8e-147 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MKDMMHLC_01104 2.5e-82 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MKDMMHLC_01105 2.2e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MKDMMHLC_01106 1e-151 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MKDMMHLC_01107 6.5e-145 rpsB J Belongs to the universal ribosomal protein uS2 family
MKDMMHLC_01108 4.7e-134 S Haloacid dehalogenase-like hydrolase
MKDMMHLC_01109 2.3e-187 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKDMMHLC_01110 7e-39 yazA L GIY-YIG catalytic domain protein
MKDMMHLC_01111 2.1e-132 yabB 2.1.1.223 L Methyltransferase small domain
MKDMMHLC_01112 6.4e-119 plsC 2.3.1.51 I Acyltransferase
MKDMMHLC_01113 4.3e-33 yneF S Uncharacterised protein family (UPF0154)
MKDMMHLC_01114 2.9e-36 ynzC S UPF0291 protein
MKDMMHLC_01115 5.6e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MKDMMHLC_01116 3.7e-87
MKDMMHLC_01117 1.8e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MKDMMHLC_01118 4.6e-75
MKDMMHLC_01119 3e-66
MKDMMHLC_01120 1.5e-177 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
MKDMMHLC_01121 9.2e-101 L Helix-turn-helix domain
MKDMMHLC_01122 2.4e-220 lytR5 K Cell envelope-related transcriptional attenuator domain
MKDMMHLC_01123 7.9e-143 P ATPases associated with a variety of cellular activities
MKDMMHLC_01124 0.0 opuAB P Binding-protein-dependent transport system inner membrane component
MKDMMHLC_01125 2.2e-229 rodA D Cell cycle protein
MKDMMHLC_01127 8.5e-165 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MKDMMHLC_01128 2.8e-182 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKDMMHLC_01129 6.9e-157 ddpX 3.4.13.22 S L,D-transpeptidase catalytic domain
MKDMMHLC_01130 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MKDMMHLC_01131 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MKDMMHLC_01132 2.6e-183 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MKDMMHLC_01133 5.4e-275 cydA 1.10.3.14 C ubiquinol oxidase
MKDMMHLC_01134 9.4e-297 S Alpha beta
MKDMMHLC_01135 1.8e-23
MKDMMHLC_01136 3e-99 S ECF transporter, substrate-specific component
MKDMMHLC_01137 5.8e-253 yfnA E Amino Acid
MKDMMHLC_01138 1.4e-165 mleP S Sodium Bile acid symporter family
MKDMMHLC_01139 4.2e-308 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MKDMMHLC_01140 1.2e-166 mleR K LysR family
MKDMMHLC_01141 4.9e-162 mleR K LysR family transcriptional regulator
MKDMMHLC_01142 1e-93 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
MKDMMHLC_01143 1.5e-261 frdC 1.3.5.4 C FAD binding domain
MKDMMHLC_01144 9.2e-256 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MKDMMHLC_01145 3e-287 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MKDMMHLC_01146 9.7e-161 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MKDMMHLC_01147 9e-44 citD C Covalent carrier of the coenzyme of citrate lyase
MKDMMHLC_01148 1.7e-188 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MKDMMHLC_01149 3e-207 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MKDMMHLC_01150 2.9e-179 citR K sugar-binding domain protein
MKDMMHLC_01151 1.7e-260 citP P Sodium:sulfate symporter transmembrane region
MKDMMHLC_01152 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKDMMHLC_01153 3.1e-50
MKDMMHLC_01154 7.9e-174 sitA P Belongs to the bacterial solute-binding protein 9 family
MKDMMHLC_01155 8.2e-141 mtsB U ABC 3 transport family
MKDMMHLC_01156 4.5e-132 mntB 3.6.3.35 P ABC transporter
MKDMMHLC_01157 1.1e-153 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MKDMMHLC_01158 7.2e-197 K Helix-turn-helix domain
MKDMMHLC_01159 2.2e-176 ttdA 4.2.1.32 C Fumarate hydratase (Fumerase)
MKDMMHLC_01160 4.1e-115 ttdB 4.2.1.2, 4.2.1.32 C Catalyzes the reversible hydration of fumarate to (S)- malate
MKDMMHLC_01161 4.1e-53 yitW S Iron-sulfur cluster assembly protein
MKDMMHLC_01162 2.2e-221 P Sodium:sulfate symporter transmembrane region
MKDMMHLC_01163 1.8e-198 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MKDMMHLC_01164 1.8e-184 aroF 2.5.1.54 E DAHP synthetase I family
MKDMMHLC_01165 1.1e-164 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKDMMHLC_01166 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKDMMHLC_01167 1.5e-163 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MKDMMHLC_01168 5.5e-30 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MKDMMHLC_01169 2.2e-173 ywhK S Membrane
MKDMMHLC_01170 2.3e-164 degV S Uncharacterised protein, DegV family COG1307
MKDMMHLC_01171 1.9e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MKDMMHLC_01172 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MKDMMHLC_01173 3.9e-150 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MKDMMHLC_01174 6.7e-142 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKDMMHLC_01175 8.2e-165 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKDMMHLC_01176 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MKDMMHLC_01177 4.4e-208 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKDMMHLC_01178 3.5e-142 cad S FMN_bind
MKDMMHLC_01179 0.0 ndh 1.6.99.3 C NADH dehydrogenase
MKDMMHLC_01180 7.2e-86 ynhH S NusG domain II
MKDMMHLC_01181 1.7e-94 gerCA 2.5.1.30 S Heptaprenyl diphosphate synthase component I
MKDMMHLC_01182 1.4e-181 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MKDMMHLC_01183 2.1e-61 rplQ J Ribosomal protein L17
MKDMMHLC_01184 5.7e-172 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDMMHLC_01185 3.4e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MKDMMHLC_01186 1.1e-59 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MKDMMHLC_01187 3.9e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MKDMMHLC_01188 2.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MKDMMHLC_01189 1.5e-236 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MKDMMHLC_01190 6.3e-70 rplO J Binds to the 23S rRNA
MKDMMHLC_01191 2.2e-24 rpmD J Ribosomal protein L30
MKDMMHLC_01192 6.8e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MKDMMHLC_01193 3.3e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MKDMMHLC_01194 3.5e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MKDMMHLC_01195 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MKDMMHLC_01196 3.2e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MKDMMHLC_01197 2.4e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MKDMMHLC_01198 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MKDMMHLC_01199 2.5e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MKDMMHLC_01200 1.4e-24 rpmC J Belongs to the universal ribosomal protein uL29 family
MKDMMHLC_01201 9.2e-77 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MKDMMHLC_01202 2.1e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MKDMMHLC_01203 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MKDMMHLC_01204 8.2e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MKDMMHLC_01205 8.1e-146 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MKDMMHLC_01206 1.8e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MKDMMHLC_01207 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MKDMMHLC_01208 1.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MKDMMHLC_01209 2.6e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MKDMMHLC_01210 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MKDMMHLC_01211 5.5e-83 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MKDMMHLC_01212 3.6e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MKDMMHLC_01213 1.6e-115 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MKDMMHLC_01214 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDMMHLC_01215 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MKDMMHLC_01216 1.5e-109 K Bacterial regulatory proteins, tetR family
MKDMMHLC_01217 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MKDMMHLC_01218 6.9e-78 ctsR K Belongs to the CtsR family
MKDMMHLC_01226 4.1e-218 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKDMMHLC_01227 2.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MKDMMHLC_01228 9.4e-114 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
MKDMMHLC_01229 1.6e-263 lysP E amino acid
MKDMMHLC_01230 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MKDMMHLC_01231 3.6e-91 K Transcriptional regulator
MKDMMHLC_01232 2.8e-99 2.3.1.128 J Acetyltransferase (GNAT) domain
MKDMMHLC_01233 2e-154 I alpha/beta hydrolase fold
MKDMMHLC_01234 3.9e-119 lssY 3.6.1.27 I phosphatase
MKDMMHLC_01235 1.5e-189 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKDMMHLC_01236 2.5e-206 lys M Glycosyl hydrolases family 25
MKDMMHLC_01237 4.7e-20
MKDMMHLC_01238 2.9e-71
MKDMMHLC_01241 2.3e-88
MKDMMHLC_01242 0.0 S Phage minor structural protein
MKDMMHLC_01243 0.0 S Phage tail protein
MKDMMHLC_01244 0.0 D NLP P60 protein
MKDMMHLC_01245 6.6e-24
MKDMMHLC_01246 1.8e-57 S Phage tail assembly chaperone proteins, TAC
MKDMMHLC_01247 3e-103 S Phage tail tube protein
MKDMMHLC_01248 3.5e-56 S Protein of unknown function (DUF806)
MKDMMHLC_01249 5.2e-66 S Bacteriophage HK97-gp10, putative tail-component
MKDMMHLC_01250 1.7e-57 S Phage head-tail joining protein
MKDMMHLC_01251 6.2e-49 S Phage gp6-like head-tail connector protein
MKDMMHLC_01252 7.5e-201 S Phage capsid family
MKDMMHLC_01253 6e-124 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MKDMMHLC_01254 5.2e-223 S Phage portal protein
MKDMMHLC_01255 2.1e-25 S Protein of unknown function (DUF1056)
MKDMMHLC_01256 0.0 S Phage Terminase
MKDMMHLC_01257 3.6e-79 L Phage terminase, small subunit
MKDMMHLC_01259 6.1e-88 L HNH nucleases
MKDMMHLC_01261 8.2e-65 S Transcriptional regulator, RinA family
MKDMMHLC_01262 1.4e-15
MKDMMHLC_01263 1.4e-55
MKDMMHLC_01264 1.2e-09 S YopX protein
MKDMMHLC_01266 7e-96 2.1.1.37 L C-5 cytosine-specific DNA methylase
MKDMMHLC_01269 3.7e-66 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MKDMMHLC_01271 1.4e-131 pi346 L IstB-like ATP binding protein
MKDMMHLC_01272 1.3e-39 S calcium ion binding
MKDMMHLC_01273 3.9e-130 S Putative HNHc nuclease
MKDMMHLC_01274 1.2e-91 S Protein of unknown function (DUF669)
MKDMMHLC_01275 8.1e-117 S AAA domain
MKDMMHLC_01276 2.8e-146 S Protein of unknown function (DUF1351)
MKDMMHLC_01278 6.3e-18
MKDMMHLC_01285 7.2e-63 S DNA binding
MKDMMHLC_01288 8.8e-20
MKDMMHLC_01289 4.5e-78 K Peptidase S24-like
MKDMMHLC_01296 3.1e-63 L Belongs to the 'phage' integrase family
MKDMMHLC_01297 3.6e-31
MKDMMHLC_01298 1.1e-138 Q Methyltransferase
MKDMMHLC_01299 8.5e-57 ybjQ S Belongs to the UPF0145 family
MKDMMHLC_01300 6.1e-211 EGP Major facilitator Superfamily
MKDMMHLC_01301 1.5e-98 K Helix-turn-helix domain
MKDMMHLC_01302 2.9e-93 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MKDMMHLC_01303 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MKDMMHLC_01304 2e-50 yrvD S Lipopolysaccharide assembly protein A domain
MKDMMHLC_01305 5.6e-141 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDMMHLC_01306 8.1e-179 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MKDMMHLC_01307 3.2e-46
MKDMMHLC_01308 2.4e-245 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MKDMMHLC_01309 1.5e-135 fruR K DeoR C terminal sensor domain
MKDMMHLC_01310 2.3e-170 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
MKDMMHLC_01311 6.7e-292 fruA 2.7.1.194, 2.7.1.200, 2.7.1.202 GT Phosphotransferase System
MKDMMHLC_01312 3.8e-251 cpdA S Calcineurin-like phosphoesterase
MKDMMHLC_01313 4.5e-261 cps4J S Polysaccharide biosynthesis protein
MKDMMHLC_01314 3e-176 cps4I M Glycosyltransferase like family 2
MKDMMHLC_01315 1.3e-232
MKDMMHLC_01316 6.5e-38 cps4G M Glycosyltransferase Family 4
MKDMMHLC_01317 2.7e-103 cps4G M Glycosyltransferase Family 4
MKDMMHLC_01318 5.6e-175 cps4F 2.4.1.21, 2.4.1.306 GT4,GT5 M Glycosyl transferases group 1
MKDMMHLC_01319 7.4e-126 tuaA M Bacterial sugar transferase
MKDMMHLC_01320 9.6e-180 cps4D 5.1.3.2 M RmlD substrate binding domain
MKDMMHLC_01321 3.5e-146 ywqE 3.1.3.48 GM PHP domain protein
MKDMMHLC_01322 2.8e-123 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MKDMMHLC_01323 2.9e-126 epsB M biosynthesis protein
MKDMMHLC_01324 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MKDMMHLC_01325 1.3e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_01326 9.2e-270 glnPH2 P ABC transporter permease
MKDMMHLC_01327 4.3e-22
MKDMMHLC_01328 9.9e-73 S Iron-sulphur cluster biosynthesis
MKDMMHLC_01329 2.2e-49 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MKDMMHLC_01330 5.1e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
MKDMMHLC_01331 3.3e-236 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MKDMMHLC_01332 1.4e-213 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MKDMMHLC_01333 6.1e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MKDMMHLC_01334 1e-157 S Tetratricopeptide repeat
MKDMMHLC_01335 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKDMMHLC_01336 6.2e-157 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MKDMMHLC_01337 7.2e-103 mdtG EGP Major Facilitator Superfamily
MKDMMHLC_01338 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MKDMMHLC_01339 1.5e-34 rpsT J Binds directly to 16S ribosomal RNA
MKDMMHLC_01340 7e-187 holA 2.7.7.7 L DNA polymerase III delta subunit
MKDMMHLC_01341 0.0 comEC S Competence protein ComEC
MKDMMHLC_01342 6.4e-79 comEB 3.5.4.12 F ComE operon protein 2
MKDMMHLC_01343 6.8e-125 comEA L Competence protein ComEA
MKDMMHLC_01344 9.6e-197 ylbL T Belongs to the peptidase S16 family
MKDMMHLC_01345 1.5e-83 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MKDMMHLC_01346 2.2e-102 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MKDMMHLC_01347 1.5e-49 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MKDMMHLC_01348 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MKDMMHLC_01349 8.2e-205 ftsW D Belongs to the SEDS family
MKDMMHLC_01350 1.2e-286
MKDMMHLC_01351 8.2e-207 ica2 GT2 M Glycosyl transferase family group 2
MKDMMHLC_01352 5.6e-19 S ATPases associated with a variety of cellular activities
MKDMMHLC_01353 3.1e-116 P cobalt transport
MKDMMHLC_01354 2e-258 P ABC transporter
MKDMMHLC_01355 3.1e-101 S ABC transporter permease
MKDMMHLC_01356 4.8e-90 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
MKDMMHLC_01357 1.4e-158 dkgB S reductase
MKDMMHLC_01358 5.3e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MKDMMHLC_01359 1e-69
MKDMMHLC_01360 4.7e-31 ygzD K Transcriptional
MKDMMHLC_01361 7.4e-132 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MKDMMHLC_01362 2.2e-173 P Major Facilitator Superfamily
MKDMMHLC_01363 5.9e-224 1.3.5.4 C FAD dependent oxidoreductase
MKDMMHLC_01364 4.8e-99 K Helix-turn-helix domain
MKDMMHLC_01365 7.4e-277 pipD E Dipeptidase
MKDMMHLC_01366 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_01367 0.0 mtlR K Mga helix-turn-helix domain
MKDMMHLC_01368 1.7e-78 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_01369 8.1e-221 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
MKDMMHLC_01370 2.1e-73
MKDMMHLC_01371 6.2e-57 trxA1 O Belongs to the thioredoxin family
MKDMMHLC_01372 1.2e-49
MKDMMHLC_01373 6.2e-94
MKDMMHLC_01374 7.7e-62
MKDMMHLC_01375 5e-81 ndk 2.7.4.6 F Belongs to the NDK family
MKDMMHLC_01376 8.4e-254 S Uncharacterized protein conserved in bacteria (DUF2252)
MKDMMHLC_01377 3.5e-97 yieF S NADPH-dependent FMN reductase
MKDMMHLC_01378 1.2e-94 cysE 2.3.1.30 E Bacterial transferase hexapeptide (six repeats)
MKDMMHLC_01379 1.4e-209 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MKDMMHLC_01380 2.5e-164 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MKDMMHLC_01381 7.8e-159 map 3.4.11.18 E Methionine Aminopeptidase
MKDMMHLC_01382 4.3e-141 pnuC H nicotinamide mononucleotide transporter
MKDMMHLC_01383 7.3e-43 S Protein of unknown function (DUF2089)
MKDMMHLC_01384 2.9e-42
MKDMMHLC_01385 3.5e-129 treR K UTRA
MKDMMHLC_01386 0.0 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
MKDMMHLC_01387 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MKDMMHLC_01388 0.0 pts4ABC 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MKDMMHLC_01389 1.4e-144
MKDMMHLC_01390 4.9e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MKDMMHLC_01391 5.8e-238 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
MKDMMHLC_01392 0.0 tagF2 2.7.8.12 H CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
MKDMMHLC_01393 5.9e-100 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
MKDMMHLC_01394 3.5e-70
MKDMMHLC_01395 1.8e-72 K Transcriptional regulator
MKDMMHLC_01396 3.7e-120 K Bacterial regulatory proteins, tetR family
MKDMMHLC_01397 6.5e-233 mntH P H( )-stimulated, divalent metal cation uptake system
MKDMMHLC_01398 5.1e-116
MKDMMHLC_01399 5.9e-38
MKDMMHLC_01400 1.4e-40
MKDMMHLC_01401 1.1e-251 ydiC1 EGP Major facilitator Superfamily
MKDMMHLC_01402 3.3e-65 K helix_turn_helix, mercury resistance
MKDMMHLC_01403 9.8e-250 T PhoQ Sensor
MKDMMHLC_01404 7e-127 K Transcriptional regulatory protein, C terminal
MKDMMHLC_01405 4.1e-49
MKDMMHLC_01406 2.7e-129 yidA K Helix-turn-helix domain, rpiR family
MKDMMHLC_01407 1e-243 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_01408 3.2e-55
MKDMMHLC_01409 2.1e-41
MKDMMHLC_01410 3.2e-184 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKDMMHLC_01411 1.1e-256 loxD 1.1.3.15 C FAD linked oxidases, C-terminal domain
MKDMMHLC_01412 1.3e-47
MKDMMHLC_01413 2.7e-123 2.7.6.5 S RelA SpoT domain protein
MKDMMHLC_01414 3.1e-104 K transcriptional regulator
MKDMMHLC_01415 0.0 ydgH S MMPL family
MKDMMHLC_01416 1.1e-106 tag 3.2.2.20 L glycosylase
MKDMMHLC_01417 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MKDMMHLC_01418 1.8e-185 yclI V MacB-like periplasmic core domain
MKDMMHLC_01419 7.1e-121 yclH V ABC transporter
MKDMMHLC_01420 2.5e-114 V CAAX protease self-immunity
MKDMMHLC_01421 4.5e-121 S CAAX protease self-immunity
MKDMMHLC_01422 7.4e-67 gcvH E Glycine cleavage H-protein
MKDMMHLC_01423 2.8e-176 sepS16B
MKDMMHLC_01424 1.8e-130
MKDMMHLC_01425 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
MKDMMHLC_01426 6.8e-57
MKDMMHLC_01427 8.9e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKDMMHLC_01428 4.9e-24 elaA S GNAT family
MKDMMHLC_01429 8.4e-75 K Transcriptional regulator
MKDMMHLC_01430 3e-226 ndh 1.6.99.3 C NADH dehydrogenase
MKDMMHLC_01431 4.3e-40
MKDMMHLC_01432 1.5e-205 potD P ABC transporter
MKDMMHLC_01433 2.9e-140 potC P ABC transporter permease
MKDMMHLC_01434 4.5e-149 potB P ABC transporter permease
MKDMMHLC_01435 3.1e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MKDMMHLC_01436 1.3e-96 puuR K Cupin domain
MKDMMHLC_01437 1.1e-83 6.3.3.2 S ASCH
MKDMMHLC_01438 1e-84 K GNAT family
MKDMMHLC_01439 8e-91 K acetyltransferase
MKDMMHLC_01440 8.1e-22
MKDMMHLC_01441 1.4e-59 ytrA K helix_turn_helix gluconate operon transcriptional repressor
MKDMMHLC_01442 2e-163 ytrB V ABC transporter
MKDMMHLC_01443 4.9e-190
MKDMMHLC_01444 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MKDMMHLC_01445 2.9e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MKDMMHLC_01446 2e-191 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MKDMMHLC_01447 3.9e-159 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MKDMMHLC_01448 1.2e-197 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MKDMMHLC_01449 9.3e-109 tdk 2.7.1.21 F thymidine kinase
MKDMMHLC_01450 4.4e-263 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
MKDMMHLC_01451 6.5e-136 cobQ S glutamine amidotransferase
MKDMMHLC_01452 2.8e-195 manA 5.3.1.8 G mannose-6-phosphate isomerase
MKDMMHLC_01453 1.2e-191 ampC V Beta-lactamase
MKDMMHLC_01454 5.2e-29
MKDMMHLC_01455 1e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
MKDMMHLC_01456 1.9e-58
MKDMMHLC_01457 2.8e-126
MKDMMHLC_01458 0.0 yfiC V ABC transporter
MKDMMHLC_01459 2.2e-310 ycfI V ABC transporter, ATP-binding protein
MKDMMHLC_01460 3.3e-65 S Protein of unknown function (DUF1093)
MKDMMHLC_01461 1.3e-132 yxkH G Polysaccharide deacetylase
MKDMMHLC_01462 3.3e-61 V Abortive infection bacteriophage resistance protein
MKDMMHLC_01463 2.7e-27 hol S Bacteriophage holin
MKDMMHLC_01464 2.2e-200 lys M Glycosyl hydrolases family 25
MKDMMHLC_01466 5.9e-21
MKDMMHLC_01467 1e-87
MKDMMHLC_01470 2.6e-15 S Domain of unknown function (DUF2479)
MKDMMHLC_01471 3.3e-96 S Domain of unknown function (DUF2479)
MKDMMHLC_01472 1.2e-172 E GDSL-like Lipase/Acylhydrolase family
MKDMMHLC_01473 1e-289 M Prophage endopeptidase tail
MKDMMHLC_01474 8.1e-134 S phage tail
MKDMMHLC_01475 0.0 D NLP P60 protein
MKDMMHLC_01477 4.3e-83 S Phage tail assembly chaperone protein, TAC
MKDMMHLC_01478 6.7e-96
MKDMMHLC_01479 4.1e-61
MKDMMHLC_01480 3.6e-94
MKDMMHLC_01481 1.7e-50
MKDMMHLC_01482 1.5e-56 S Phage gp6-like head-tail connector protein
MKDMMHLC_01483 1.5e-194 gpG
MKDMMHLC_01484 8.6e-71 S Domain of unknown function (DUF4355)
MKDMMHLC_01485 2.9e-168 S Phage Mu protein F like protein
MKDMMHLC_01486 7.6e-305 S Phage portal protein, SPP1 Gp6-like
MKDMMHLC_01487 8.7e-248 S Phage terminase, large subunit
MKDMMHLC_01489 2e-75 ps333 L Terminase small subunit
MKDMMHLC_01490 3.5e-11
MKDMMHLC_01492 2.2e-17
MKDMMHLC_01493 6.6e-31 rplV S ASCH
MKDMMHLC_01494 1.3e-79 K acetyltransferase
MKDMMHLC_01498 4.1e-14
MKDMMHLC_01499 2.4e-13 S YopX protein
MKDMMHLC_01501 4.9e-63 rusA 3.1.22.4 L Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MKDMMHLC_01502 2.2e-50
MKDMMHLC_01503 2.5e-161 L DnaD domain protein
MKDMMHLC_01504 1.4e-64
MKDMMHLC_01505 1.6e-54 S Bacteriophage Mu Gam like protein
MKDMMHLC_01507 2.8e-85
MKDMMHLC_01508 4.5e-54
MKDMMHLC_01510 1.3e-37 K Helix-turn-helix
MKDMMHLC_01511 4.5e-61 yvaO K Helix-turn-helix domain
MKDMMHLC_01512 3.3e-76 E IrrE N-terminal-like domain
MKDMMHLC_01513 8.4e-37
MKDMMHLC_01515 4.1e-13 S DNA/RNA non-specific endonuclease
MKDMMHLC_01519 7.3e-219 int L Belongs to the 'phage' integrase family
MKDMMHLC_01521 8.9e-30
MKDMMHLC_01524 3.6e-61
MKDMMHLC_01525 1.1e-35 S Phage gp6-like head-tail connector protein
MKDMMHLC_01526 7.2e-278 S Caudovirus prohead serine protease
MKDMMHLC_01527 1.1e-203 S Phage portal protein
MKDMMHLC_01529 0.0 terL S overlaps another CDS with the same product name
MKDMMHLC_01530 2.5e-83 terS L Phage terminase, small subunit
MKDMMHLC_01531 1.6e-67 L Phage-associated protein
MKDMMHLC_01532 4.6e-47 S head-tail joining protein
MKDMMHLC_01534 7e-74
MKDMMHLC_01535 7.9e-263 S Virulence-associated protein E
MKDMMHLC_01536 4.1e-147 L DNA replication protein
MKDMMHLC_01537 1.6e-29
MKDMMHLC_01541 6.4e-226 sip L Belongs to the 'phage' integrase family
MKDMMHLC_01542 2e-38
MKDMMHLC_01543 1.4e-43
MKDMMHLC_01544 7.3e-83 K MarR family
MKDMMHLC_01545 0.0 bztC D nuclear chromosome segregation
MKDMMHLC_01546 2.8e-167 M MucBP domain
MKDMMHLC_01547 1.5e-14
MKDMMHLC_01548 4.7e-16
MKDMMHLC_01549 2.6e-14
MKDMMHLC_01550 4.2e-18
MKDMMHLC_01551 1.6e-16
MKDMMHLC_01552 0.0 msbA2 3.6.3.44 P ABC transporter transmembrane region
MKDMMHLC_01553 2e-61 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01554 2e-198 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01555 0.0 macB3 V ABC transporter, ATP-binding protein
MKDMMHLC_01556 6.8e-24
MKDMMHLC_01557 1e-259 pgi 5.3.1.9 G Belongs to the GPI family
MKDMMHLC_01558 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MKDMMHLC_01559 1.1e-34 ykuJ S Protein of unknown function (DUF1797)
MKDMMHLC_01560 1.1e-225 patA 2.6.1.1 E Aminotransferase
MKDMMHLC_01561 1.9e-228 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MKDMMHLC_01562 7.4e-189 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MKDMMHLC_01563 6.9e-200 cpoA GT4 M Glycosyltransferase, group 1 family protein
MKDMMHLC_01564 1.4e-223 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MKDMMHLC_01565 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MKDMMHLC_01566 2.7e-39 ptsH G phosphocarrier protein HPR
MKDMMHLC_01567 6.5e-30
MKDMMHLC_01568 0.0 clpE O Belongs to the ClpA ClpB family
MKDMMHLC_01569 2.2e-73 L Integrase
MKDMMHLC_01570 1e-63 K Winged helix DNA-binding domain
MKDMMHLC_01571 1.8e-181 oppF P Belongs to the ABC transporter superfamily
MKDMMHLC_01572 9.2e-203 oppD P Belongs to the ABC transporter superfamily
MKDMMHLC_01573 1.1e-189 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKDMMHLC_01574 2.3e-165 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
MKDMMHLC_01575 1.3e-309 oppA E ABC transporter, substratebinding protein
MKDMMHLC_01576 3.2e-57 ywjH S Protein of unknown function (DUF1634)
MKDMMHLC_01577 5.5e-126 yxaA S membrane transporter protein
MKDMMHLC_01578 7.1e-161 lysR5 K LysR substrate binding domain
MKDMMHLC_01579 2.7e-196 M MucBP domain
MKDMMHLC_01580 1.7e-273
MKDMMHLC_01581 6.9e-308 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MKDMMHLC_01582 2.4e-253 gor 1.8.1.7 C Glutathione reductase
MKDMMHLC_01583 1.7e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
MKDMMHLC_01584 3e-292 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
MKDMMHLC_01585 9.5e-213 gntP EG Gluconate
MKDMMHLC_01586 3.7e-72 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
MKDMMHLC_01587 9.3e-188 yueF S AI-2E family transporter
MKDMMHLC_01588 3.4e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MKDMMHLC_01589 1.3e-27 S Antitoxin component of a toxin-antitoxin (TA) module
MKDMMHLC_01590 7.8e-48 K sequence-specific DNA binding
MKDMMHLC_01591 2.5e-133 cwlO M NlpC/P60 family
MKDMMHLC_01592 4.1e-106 ygaC J Belongs to the UPF0374 family
MKDMMHLC_01593 2.2e-140 recX 2.4.1.337 GT4 S Regulatory protein RecX
MKDMMHLC_01594 3e-125
MKDMMHLC_01595 6.8e-101 K DNA-templated transcription, initiation
MKDMMHLC_01596 1.3e-25
MKDMMHLC_01597 7e-30
MKDMMHLC_01598 7.3e-33 S Protein of unknown function (DUF2922)
MKDMMHLC_01599 3.8e-53
MKDMMHLC_01600 2.2e-17 L Helix-turn-helix domain
MKDMMHLC_01601 9.7e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_01602 1.4e-154 yihY S Belongs to the UPF0761 family
MKDMMHLC_01603 1.5e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MKDMMHLC_01604 1.2e-219 pbpX1 V Beta-lactamase
MKDMMHLC_01605 8.4e-254 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
MKDMMHLC_01606 1.4e-106
MKDMMHLC_01607 1.3e-73
MKDMMHLC_01609 2e-163 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_01610 2.9e-243 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_01611 2.3e-75 T Universal stress protein family
MKDMMHLC_01613 2.6e-239 yfmL 3.6.4.13 L DEAD DEAH box helicase
MKDMMHLC_01614 2.4e-189 mocA S Oxidoreductase
MKDMMHLC_01615 2.7e-31 cspA K 'Cold-shock' DNA-binding domain
MKDMMHLC_01616 1.1e-62 S Domain of unknown function (DUF4828)
MKDMMHLC_01617 2e-143 lys M Glycosyl hydrolases family 25
MKDMMHLC_01618 2.3e-151 gntR K rpiR family
MKDMMHLC_01619 6.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_01620 4e-240 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_01621 0.0 yfgQ P E1-E2 ATPase
MKDMMHLC_01622 6e-100 yobS K Bacterial regulatory proteins, tetR family
MKDMMHLC_01623 4e-259 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKDMMHLC_01624 1e-190 yegS 2.7.1.107 G Lipid kinase
MKDMMHLC_01625 7.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKDMMHLC_01626 2.5e-275 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MKDMMHLC_01627 3.2e-50 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MKDMMHLC_01628 2.6e-198 camS S sex pheromone
MKDMMHLC_01629 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MKDMMHLC_01630 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MKDMMHLC_01631 1.3e-218 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MKDMMHLC_01632 1e-93 S UPF0316 protein
MKDMMHLC_01633 9.1e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MKDMMHLC_01634 3.4e-112 acmA 3.2.1.17 NU mannosyl-glycoprotein
MKDMMHLC_01635 7.3e-183 S Oxidoreductase family, NAD-binding Rossmann fold
MKDMMHLC_01636 4.5e-123 yliE T EAL domain
MKDMMHLC_01637 6.4e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
MKDMMHLC_01638 3.1e-104 K Bacterial regulatory proteins, tetR family
MKDMMHLC_01639 1.2e-207 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MKDMMHLC_01640 1.5e-52
MKDMMHLC_01641 3e-72
MKDMMHLC_01642 3e-131 1.5.1.39 C nitroreductase
MKDMMHLC_01643 8.8e-154 G Transmembrane secretion effector
MKDMMHLC_01644 3.1e-297 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKDMMHLC_01645 2.1e-143
MKDMMHLC_01647 1.9e-71 spxA 1.20.4.1 P ArsC family
MKDMMHLC_01648 1.5e-33
MKDMMHLC_01649 2.5e-89 V VanZ like family
MKDMMHLC_01650 3.6e-242 EGP Major facilitator Superfamily
MKDMMHLC_01651 3.2e-175 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MKDMMHLC_01652 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MKDMMHLC_01653 4.1e-289 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MKDMMHLC_01654 2.5e-152 licD M LicD family
MKDMMHLC_01655 1.2e-82 K Transcriptional regulator
MKDMMHLC_01656 1.5e-19
MKDMMHLC_01657 1.2e-225 pbuG S permease
MKDMMHLC_01658 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKDMMHLC_01659 1.8e-153 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MKDMMHLC_01660 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKDMMHLC_01661 5.5e-180 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MKDMMHLC_01662 5.9e-180 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKDMMHLC_01663 0.0 oatA I Acyltransferase
MKDMMHLC_01664 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MKDMMHLC_01665 1.1e-68 O OsmC-like protein
MKDMMHLC_01666 2.6e-46
MKDMMHLC_01667 1.1e-251 yfnA E Amino Acid
MKDMMHLC_01668 2.5e-88
MKDMMHLC_01669 1.6e-146 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
MKDMMHLC_01670 4.6e-73 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MKDMMHLC_01671 1.8e-19
MKDMMHLC_01672 1.2e-103 gmk2 2.7.4.8 F Guanylate kinase
MKDMMHLC_01673 1.3e-81 zur P Belongs to the Fur family
MKDMMHLC_01674 7.1e-12 3.2.1.14 GH18
MKDMMHLC_01675 4.9e-148
MKDMMHLC_01676 1.7e-73 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MKDMMHLC_01677 3.2e-184 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MKDMMHLC_01678 9.5e-170 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKDMMHLC_01679 3.6e-41
MKDMMHLC_01681 9e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_01682 7.8e-149 glnH ET ABC transporter substrate-binding protein
MKDMMHLC_01683 1.6e-109 gluC P ABC transporter permease
MKDMMHLC_01684 4e-108 glnP P ABC transporter permease
MKDMMHLC_01685 4.4e-83 G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKDMMHLC_01686 1.4e-153 K CAT RNA binding domain
MKDMMHLC_01687 4.4e-256 2.7.1.193, 2.7.1.211 G phosphotransferase system, EIIB
MKDMMHLC_01688 6.1e-140 G YdjC-like protein
MKDMMHLC_01689 1.4e-245 steT E amino acid
MKDMMHLC_01690 7.4e-74 mgrA K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_01691 3.7e-149 XK27_00825 S Sulfite exporter TauE/SafE
MKDMMHLC_01692 2.8e-70 K MarR family
MKDMMHLC_01693 4.9e-210 EGP Major facilitator Superfamily
MKDMMHLC_01694 3.8e-85 S membrane transporter protein
MKDMMHLC_01695 7.1e-98 K Bacterial regulatory proteins, tetR family
MKDMMHLC_01696 8.7e-232 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MKDMMHLC_01697 2.9e-78 3.6.1.55 F NUDIX domain
MKDMMHLC_01698 1.3e-48 sugE U Multidrug resistance protein
MKDMMHLC_01699 1.2e-26
MKDMMHLC_01700 5.5e-129 pgm3 G Phosphoglycerate mutase family
MKDMMHLC_01701 4.7e-125 pgm3 G Phosphoglycerate mutase family
MKDMMHLC_01702 0.0 yjbQ P TrkA C-terminal domain protein
MKDMMHLC_01703 3.1e-178 yqkA 3.6.1.55 F Belongs to the Nudix hydrolase family
MKDMMHLC_01704 7.2e-110 dedA S SNARE associated Golgi protein
MKDMMHLC_01705 0.0 helD 3.6.4.12 L DNA helicase
MKDMMHLC_01706 2.5e-164 fabK 1.3.1.9 S Nitronate monooxygenase
MKDMMHLC_01707 2.5e-177 coaA 2.7.1.33 F Pantothenic acid kinase
MKDMMHLC_01708 2.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MKDMMHLC_01710 5.1e-143 spoVK O ATPase family associated with various cellular activities (AAA)
MKDMMHLC_01712 7.6e-46 L Helix-turn-helix domain
MKDMMHLC_01713 6.9e-29 L hmm pf00665
MKDMMHLC_01714 8.9e-23 L hmm pf00665
MKDMMHLC_01715 4.3e-78
MKDMMHLC_01716 6.2e-50
MKDMMHLC_01717 1.7e-63 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_01722 5.1e-08
MKDMMHLC_01728 2.8e-91 apt 2.4.2.22, 2.4.2.7 F Phosphoribosyl transferase domain
MKDMMHLC_01729 8.9e-182 P secondary active sulfate transmembrane transporter activity
MKDMMHLC_01730 1.4e-95
MKDMMHLC_01731 2e-94 K Acetyltransferase (GNAT) domain
MKDMMHLC_01732 8.6e-37 T Calcineurin-like phosphoesterase superfamily domain
MKDMMHLC_01733 3.3e-104 T Calcineurin-like phosphoesterase superfamily domain
MKDMMHLC_01735 3.7e-230 mntH P H( )-stimulated, divalent metal cation uptake system
MKDMMHLC_01736 4e-189 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MKDMMHLC_01737 9.2e-256 mmuP E amino acid
MKDMMHLC_01738 7.5e-169 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
MKDMMHLC_01739 1.5e-291 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01740 1.6e-121
MKDMMHLC_01741 4.1e-212 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MKDMMHLC_01742 5.5e-278 bmr3 EGP Major facilitator Superfamily
MKDMMHLC_01743 1.7e-18 N Cell shape-determining protein MreB
MKDMMHLC_01744 2.1e-139 N Cell shape-determining protein MreB
MKDMMHLC_01745 0.0 S Pfam Methyltransferase
MKDMMHLC_01746 3.3e-267 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01747 2.2e-298 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01748 4.2e-29
MKDMMHLC_01749 1.2e-94 ytqB 2.1.1.176 J Putative rRNA methylase
MKDMMHLC_01750 1.4e-124 3.6.1.27 I Acid phosphatase homologues
MKDMMHLC_01751 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKDMMHLC_01752 3e-301 ytgP S Polysaccharide biosynthesis protein
MKDMMHLC_01753 1.8e-136 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MKDMMHLC_01754 1.9e-150 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MKDMMHLC_01755 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
MKDMMHLC_01756 4.1e-84 uspA T Belongs to the universal stress protein A family
MKDMMHLC_01757 5.2e-201 ugpC 3.6.3.20 E Belongs to the ABC transporter superfamily
MKDMMHLC_01758 5.2e-173 ugpA U Binding-protein-dependent transport system inner membrane component
MKDMMHLC_01759 1.1e-150 ugpE G ABC transporter permease
MKDMMHLC_01760 2.5e-180 ugpB G Bacterial extracellular solute-binding protein
MKDMMHLC_01761 3.8e-119 dck 2.7.1.74 F deoxynucleoside kinase
MKDMMHLC_01762 5.5e-41 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MKDMMHLC_01763 3.9e-179 XK27_06930 V domain protein
MKDMMHLC_01765 2.6e-124 V Transport permease protein
MKDMMHLC_01766 2.3e-156 V ABC transporter
MKDMMHLC_01767 4e-176 K LytTr DNA-binding domain
MKDMMHLC_01769 3.1e-155 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MKDMMHLC_01770 1.6e-64 K helix_turn_helix, mercury resistance
MKDMMHLC_01771 3.5e-117 GM NAD(P)H-binding
MKDMMHLC_01772 9.3e-159 ypaH EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
MKDMMHLC_01773 3.2e-147 S Sucrose-6F-phosphate phosphohydrolase
MKDMMHLC_01774 1.7e-108
MKDMMHLC_01775 2.5e-223 pltK 2.7.13.3 T GHKL domain
MKDMMHLC_01776 1.6e-137 pltR K LytTr DNA-binding domain
MKDMMHLC_01777 4.5e-55
MKDMMHLC_01778 2.5e-59
MKDMMHLC_01779 1.9e-113 S CAAX protease self-immunity
MKDMMHLC_01780 1.6e-85 ohrR K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_01781 1e-90
MKDMMHLC_01782 2.5e-46
MKDMMHLC_01783 0.0 uvrA2 L ABC transporter
MKDMMHLC_01786 5.9e-52
MKDMMHLC_01787 3.5e-10
MKDMMHLC_01788 2.1e-180
MKDMMHLC_01789 1.9e-89 gtcA S Teichoic acid glycosylation protein
MKDMMHLC_01790 3.6e-58 S Protein of unknown function (DUF1516)
MKDMMHLC_01791 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
MKDMMHLC_01792 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
MKDMMHLC_01793 1.2e-307 S Protein conserved in bacteria
MKDMMHLC_01794 1.6e-229 sat 2.7.7.4 H the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms
MKDMMHLC_01795 7.4e-112 cysC 2.7.1.25, 2.7.7.4 F Catalyzes the synthesis of activated sulfate
MKDMMHLC_01796 8.5e-176 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain
MKDMMHLC_01797 2.1e-305 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
MKDMMHLC_01798 0.0 yfbS P Sodium:sulfate symporter transmembrane region
MKDMMHLC_01799 2.9e-148 yxeH S hydrolase
MKDMMHLC_01800 9e-264 ywfO S HD domain protein
MKDMMHLC_01801 4.7e-157 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MKDMMHLC_01802 3.8e-78 ywiB S Domain of unknown function (DUF1934)
MKDMMHLC_01803 4e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MKDMMHLC_01804 3.4e-310 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MKDMMHLC_01805 4.7e-246 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MKDMMHLC_01806 3.1e-229 tdcC E amino acid
MKDMMHLC_01807 9.8e-123 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MKDMMHLC_01808 7.6e-158 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MKDMMHLC_01809 6.4e-131 S YheO-like PAS domain
MKDMMHLC_01810 2.5e-26
MKDMMHLC_01811 3.6e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MKDMMHLC_01812 6.6e-240 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MKDMMHLC_01813 7.8e-41 rpmE2 J Ribosomal protein L31
MKDMMHLC_01814 3.2e-214 J translation release factor activity
MKDMMHLC_01815 9.2e-127 srtA 3.4.22.70 M sortase family
MKDMMHLC_01816 1.7e-91 lemA S LemA family
MKDMMHLC_01817 4.6e-139 htpX O Belongs to the peptidase M48B family
MKDMMHLC_01818 2e-146
MKDMMHLC_01819 3.6e-260 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MKDMMHLC_01820 6.6e-258 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MKDMMHLC_01821 1e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MKDMMHLC_01822 9.3e-214 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MKDMMHLC_01823 1.6e-64 ndoA L Toxic component of a toxin-antitoxin (TA) module
MKDMMHLC_01824 0.0 kup P Transport of potassium into the cell
MKDMMHLC_01825 2.9e-193 P ABC transporter, substratebinding protein
MKDMMHLC_01826 2.2e-129 ssuC2 U Binding-protein-dependent transport system inner membrane component
MKDMMHLC_01827 1.9e-133 P ATPases associated with a variety of cellular activities
MKDMMHLC_01828 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MKDMMHLC_01829 8.3e-204 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MKDMMHLC_01830 7.2e-189 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MKDMMHLC_01831 1.3e-229 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MKDMMHLC_01832 9.4e-130 argB 2.7.2.8 F Belongs to the acetylglutamate kinase family. ArgB subfamily
MKDMMHLC_01833 5.1e-215 argD 2.6.1.11, 2.6.1.17 E acetylornithine
MKDMMHLC_01834 3.6e-188 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MKDMMHLC_01835 4.1e-84 S QueT transporter
MKDMMHLC_01836 6.2e-114 S (CBS) domain
MKDMMHLC_01837 4.2e-264 S Putative peptidoglycan binding domain
MKDMMHLC_01838 3.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MKDMMHLC_01839 1.5e-100 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MKDMMHLC_01840 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MKDMMHLC_01841 4.3e-289 yabM S Polysaccharide biosynthesis protein
MKDMMHLC_01842 2.2e-42 yabO J S4 domain protein
MKDMMHLC_01844 1.1e-63 divIC D Septum formation initiator
MKDMMHLC_01845 3.1e-74 yabR J RNA binding
MKDMMHLC_01846 6.4e-254 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MKDMMHLC_01847 1.7e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MKDMMHLC_01848 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MKDMMHLC_01849 1.2e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MKDMMHLC_01850 1.1e-189 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKDMMHLC_01851 3e-292 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MKDMMHLC_01852 2.1e-31
MKDMMHLC_01853 4.4e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKDMMHLC_01854 1.3e-94 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
MKDMMHLC_01855 6.1e-76 T Belongs to the universal stress protein A family
MKDMMHLC_01856 1.3e-34
MKDMMHLC_01857 1.4e-150 IQ Enoyl-(Acyl carrier protein) reductase
MKDMMHLC_01858 1.5e-194 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MKDMMHLC_01859 1.9e-104 GM NAD(P)H-binding
MKDMMHLC_01860 6.9e-156 K LysR substrate binding domain
MKDMMHLC_01861 3.8e-63 S Domain of unknown function (DUF4440)
MKDMMHLC_01862 1.4e-110 pgm8 G Histidine phosphatase superfamily (branch 1)
MKDMMHLC_01863 8.2e-48
MKDMMHLC_01864 3.2e-37
MKDMMHLC_01865 2.8e-85 yvbK 3.1.3.25 K GNAT family
MKDMMHLC_01866 3.8e-84
MKDMMHLC_01868 8.4e-116 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MKDMMHLC_01869 2.2e-100 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
MKDMMHLC_01870 2.3e-116 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MKDMMHLC_01872 7.5e-121 macB V ABC transporter, ATP-binding protein
MKDMMHLC_01873 0.0 ylbB V ABC transporter permease
MKDMMHLC_01874 1.4e-234 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MKDMMHLC_01875 2.9e-78 K transcriptional regulator, MerR family
MKDMMHLC_01876 3.2e-76 yphH S Cupin domain
MKDMMHLC_01877 7.3e-55 yphJ 4.1.1.44 S Carboxymuconolactone decarboxylase family
MKDMMHLC_01878 1.4e-128 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDMMHLC_01879 1.4e-210 natB CP ABC-2 family transporter protein
MKDMMHLC_01880 7.5e-166 natA S ABC transporter, ATP-binding protein
MKDMMHLC_01881 1.2e-91 ogt 2.1.1.63 L Methyltransferase
MKDMMHLC_01882 1.8e-46 lytE M LysM domain
MKDMMHLC_01884 6.9e-268 tagE6 2.4.1.52 GT4 M Glycosyl transferases group 1
MKDMMHLC_01885 7.6e-296 tagE5 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MKDMMHLC_01886 4.8e-151 rlrG K Transcriptional regulator
MKDMMHLC_01887 9.3e-173 S Conserved hypothetical protein 698
MKDMMHLC_01888 1.8e-101 rimL J Acetyltransferase (GNAT) domain
MKDMMHLC_01889 2e-75 S Domain of unknown function (DUF4811)
MKDMMHLC_01890 4.1e-270 lmrB EGP Major facilitator Superfamily
MKDMMHLC_01891 2.8e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
MKDMMHLC_01892 1.3e-189 ynfM EGP Major facilitator Superfamily
MKDMMHLC_01893 8.5e-257 aspA 4.2.1.2, 4.3.1.1 E Fumarase C C-terminus
MKDMMHLC_01894 1.2e-155 mleP3 S Membrane transport protein
MKDMMHLC_01895 6.4e-117 S Membrane
MKDMMHLC_01896 1.1e-185 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKDMMHLC_01897 8.1e-99 1.5.1.3 H RibD C-terminal domain
MKDMMHLC_01898 4.2e-186 iunH 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MKDMMHLC_01899 3.7e-91 2.7.7.65 T phosphorelay sensor kinase activity
MKDMMHLC_01900 2.8e-120 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MKDMMHLC_01901 5.2e-174 hrtB V ABC transporter permease
MKDMMHLC_01902 6.6e-95 S Protein of unknown function (DUF1440)
MKDMMHLC_01903 1.7e-227 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MKDMMHLC_01904 6.4e-148 KT helix_turn_helix, mercury resistance
MKDMMHLC_01905 1.6e-115 S Protein of unknown function (DUF554)
MKDMMHLC_01906 1.1e-92 yueI S Protein of unknown function (DUF1694)
MKDMMHLC_01907 2e-143 yvpB S Peptidase_C39 like family
MKDMMHLC_01908 2.4e-149 M Glycosyl hydrolases family 25
MKDMMHLC_01909 3.9e-111
MKDMMHLC_01910 1.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MKDMMHLC_01911 1.8e-84 hmpT S Pfam:DUF3816
MKDMMHLC_01912 1.1e-306 U Belongs to the BCCT transporter (TC 2.A.15) family
MKDMMHLC_01913 0.0 cadA P P-type ATPase
MKDMMHLC_01915 2.5e-124 yyaQ S YjbR
MKDMMHLC_01916 2.9e-29 S Uncharacterized protein conserved in bacteria (DUF2325)
MKDMMHLC_01917 2.8e-168 S Uncharacterized protein conserved in bacteria (DUF2325)
MKDMMHLC_01918 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MKDMMHLC_01919 2.2e-199 frlB M SIS domain
MKDMMHLC_01920 3e-26 3.2.2.10 S Belongs to the LOG family
MKDMMHLC_01921 3.4e-253 nhaC C Na H antiporter NhaC
MKDMMHLC_01922 1.3e-249 cycA E Amino acid permease
MKDMMHLC_01923 5.7e-73 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_01924 2.7e-71 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_01925 1.6e-85 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MKDMMHLC_01926 7.7e-160 azoB GM NmrA-like family
MKDMMHLC_01927 5.4e-66 K Winged helix DNA-binding domain
MKDMMHLC_01928 7e-71 spx4 1.20.4.1 P ArsC family
MKDMMHLC_01929 1.7e-66 yeaO S Protein of unknown function, DUF488
MKDMMHLC_01930 4e-53
MKDMMHLC_01931 4.1e-214 mutY L A G-specific adenine glycosylase
MKDMMHLC_01932 1.9e-62
MKDMMHLC_01933 4.3e-86
MKDMMHLC_01934 2e-79 hsp3 O Belongs to the small heat shock protein (HSP20) family
MKDMMHLC_01935 5.9e-55
MKDMMHLC_01936 2.1e-14
MKDMMHLC_01937 1.1e-115 GM NmrA-like family
MKDMMHLC_01938 1.3e-81 elaA S GNAT family
MKDMMHLC_01939 5.9e-158 EG EamA-like transporter family
MKDMMHLC_01940 1.8e-119 S membrane
MKDMMHLC_01941 6.8e-111 S VIT family
MKDMMHLC_01942 1.3e-190 pva2 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
MKDMMHLC_01943 0.0 copB 3.6.3.4 P P-type ATPase
MKDMMHLC_01944 4.7e-73 copR K Copper transport repressor CopY TcrY
MKDMMHLC_01945 7.4e-40
MKDMMHLC_01946 7.7e-73 S COG NOG18757 non supervised orthologous group
MKDMMHLC_01947 1.5e-248 lmrB EGP Major facilitator Superfamily
MKDMMHLC_01948 3.4e-25
MKDMMHLC_01949 4.2e-49
MKDMMHLC_01950 1.6e-64 ycgX S Protein of unknown function (DUF1398)
MKDMMHLC_01951 5.2e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MKDMMHLC_01952 5.9e-214 mdtG EGP Major facilitator Superfamily
MKDMMHLC_01953 2.6e-180 D Alpha beta
MKDMMHLC_01954 3.1e-78 M1-874 K Domain of unknown function (DUF1836)
MKDMMHLC_01955 5.9e-85 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MKDMMHLC_01956 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
MKDMMHLC_01957 6.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
MKDMMHLC_01958 8.4e-152 ywkB S Membrane transport protein
MKDMMHLC_01959 5.2e-164 yvgN C Aldo keto reductase
MKDMMHLC_01960 9.2e-133 thrE S Putative threonine/serine exporter
MKDMMHLC_01961 7.5e-77 S Threonine/Serine exporter, ThrE
MKDMMHLC_01962 2.3e-43 S Protein of unknown function (DUF1093)
MKDMMHLC_01963 1.1e-147 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
MKDMMHLC_01964 2.7e-91 ymdB S Macro domain protein
MKDMMHLC_01965 1.2e-95 K transcriptional regulator
MKDMMHLC_01966 5.5e-50 yvlA
MKDMMHLC_01967 6e-161 ypuA S Protein of unknown function (DUF1002)
MKDMMHLC_01968 0.0
MKDMMHLC_01969 1.7e-121 S Bacterial protein of unknown function (DUF916)
MKDMMHLC_01970 1.1e-161 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MKDMMHLC_01971 3.4e-191 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MKDMMHLC_01972 2.9e-284 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MKDMMHLC_01973 1.6e-180 galR K Transcriptional regulator
MKDMMHLC_01974 8e-76 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_01975 2.4e-22 fic D Fic/DOC family
MKDMMHLC_01976 1.9e-25 fic D Fic/DOC family
MKDMMHLC_01977 2.1e-38 fic D Fic/DOC family
MKDMMHLC_01978 7.4e-183 rhaR K helix_turn_helix, arabinose operon control protein
MKDMMHLC_01979 2.5e-231 EGP Major facilitator Superfamily
MKDMMHLC_01980 2.1e-304 ram2 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MKDMMHLC_01981 2.3e-229 mdtH P Sugar (and other) transporter
MKDMMHLC_01982 0.0 3.2.1.40 G Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain
MKDMMHLC_01983 1.4e-248 brnQ U Component of the transport system for branched-chain amino acids
MKDMMHLC_01984 0.0 ubiB S ABC1 family
MKDMMHLC_01985 1.8e-108 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_01986 3.9e-218 3.1.3.1 S associated with various cellular activities
MKDMMHLC_01987 1.4e-248 S Putative metallopeptidase domain
MKDMMHLC_01988 1.5e-49
MKDMMHLC_01989 7.7e-103 K Bacterial regulatory proteins, tetR family
MKDMMHLC_01990 4.6e-45
MKDMMHLC_01991 2.3e-99 S WxL domain surface cell wall-binding
MKDMMHLC_01992 1.5e-118 S WxL domain surface cell wall-binding
MKDMMHLC_01993 6.1e-164 S Cell surface protein
MKDMMHLC_01994 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
MKDMMHLC_01995 1.3e-262 nox C NADH oxidase
MKDMMHLC_01996 3.2e-83 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MKDMMHLC_01997 0.0 pepO 3.4.24.71 O Peptidase family M13
MKDMMHLC_01998 3.3e-118 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MKDMMHLC_01999 1.6e-32 copZ P Heavy-metal-associated domain
MKDMMHLC_02000 6.6e-96 dps P Belongs to the Dps family
MKDMMHLC_02001 1.2e-18
MKDMMHLC_02002 4.3e-40 yrkD S Metal-sensitive transcriptional repressor
MKDMMHLC_02003 1.5e-55 txlA O Thioredoxin-like domain
MKDMMHLC_02004 6.3e-142 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_02005 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
MKDMMHLC_02006 1.1e-181 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MKDMMHLC_02007 6.3e-128 ydcF S Gram-negative-bacterium-type cell wall biogenesis
MKDMMHLC_02008 1.3e-136 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MKDMMHLC_02009 1.4e-181 yfeX P Peroxidase
MKDMMHLC_02010 1.3e-102 K transcriptional regulator
MKDMMHLC_02011 1.7e-07 4.1.1.46 S metal-dependent hydrolase of the TIM-barrel fold
MKDMMHLC_02012 2.6e-65
MKDMMHLC_02014 1.6e-61
MKDMMHLC_02015 2.5e-53
MKDMMHLC_02016 2e-72 mltD CBM50 M PFAM NLP P60 protein
MKDMMHLC_02017 4.6e-279 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
MKDMMHLC_02018 1.8e-27
MKDMMHLC_02019 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
MKDMMHLC_02020 2.4e-116 luxT K Bacterial regulatory proteins, tetR family
MKDMMHLC_02021 1.3e-87 K Winged helix DNA-binding domain
MKDMMHLC_02022 1.3e-136 T Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain
MKDMMHLC_02023 5.1e-129 S WxL domain surface cell wall-binding
MKDMMHLC_02024 2e-56 S Bacterial protein of unknown function (DUF916)
MKDMMHLC_02025 3.9e-11 ica2 GT2 M Glycosyl transferase family group 2
MKDMMHLC_02026 1.2e-103
MKDMMHLC_02027 1.1e-172
MKDMMHLC_02028 0.0 typA T GTP-binding protein TypA
MKDMMHLC_02029 3.1e-136 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MKDMMHLC_02030 3.3e-46 yktA S Belongs to the UPF0223 family
MKDMMHLC_02031 4.7e-163 1.1.1.27 C L-malate dehydrogenase activity
MKDMMHLC_02032 1.2e-266 lpdA 1.8.1.4 C Dehydrogenase
MKDMMHLC_02033 1.8e-208 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MKDMMHLC_02034 8.4e-179 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MKDMMHLC_02035 1.6e-210 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MKDMMHLC_02036 3.1e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MKDMMHLC_02037 1.6e-85
MKDMMHLC_02038 3.1e-33 ykzG S Belongs to the UPF0356 family
MKDMMHLC_02039 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MKDMMHLC_02040 2.2e-187 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
MKDMMHLC_02041 1.7e-28
MKDMMHLC_02042 2.6e-107 mltD CBM50 M NlpC P60 family protein
MKDMMHLC_02043 4.4e-172 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKDMMHLC_02044 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MKDMMHLC_02045 1.6e-120 S Repeat protein
MKDMMHLC_02046 5.5e-121 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MKDMMHLC_02047 1.6e-266 N domain, Protein
MKDMMHLC_02048 1.9e-192 S Bacterial protein of unknown function (DUF916)
MKDMMHLC_02049 2.3e-120 N WxL domain surface cell wall-binding
MKDMMHLC_02050 2.6e-115 ktrA P domain protein
MKDMMHLC_02051 1.3e-241 ktrB P Potassium uptake protein
MKDMMHLC_02052 9.1e-225 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MKDMMHLC_02053 4.9e-57 XK27_04120 S Putative amino acid metabolism
MKDMMHLC_02054 2.6e-214 iscS 2.8.1.7 E Aminotransferase class V
MKDMMHLC_02055 1.8e-122 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MKDMMHLC_02056 4.6e-28
MKDMMHLC_02057 1.9e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MKDMMHLC_02058 1.1e-189 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MKDMMHLC_02059 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MKDMMHLC_02060 1.2e-86 divIVA D DivIVA domain protein
MKDMMHLC_02061 3.4e-146 ylmH S S4 domain protein
MKDMMHLC_02062 1.2e-36 yggT S YGGT family
MKDMMHLC_02063 3.3e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MKDMMHLC_02064 1.4e-229 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MKDMMHLC_02065 5.5e-245 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MKDMMHLC_02066 5.8e-163 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MKDMMHLC_02067 3.4e-197 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MKDMMHLC_02068 1.2e-260 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MKDMMHLC_02069 8.3e-179 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MKDMMHLC_02070 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MKDMMHLC_02071 7.5e-54 ftsL D Cell division protein FtsL
MKDMMHLC_02072 5.5e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MKDMMHLC_02073 1.9e-77 mraZ K Belongs to the MraZ family
MKDMMHLC_02074 1.9e-62 S Protein of unknown function (DUF3397)
MKDMMHLC_02075 1.6e-174 corA P CorA-like Mg2+ transporter protein
MKDMMHLC_02076 2e-77 merR K MerR family regulatory protein
MKDMMHLC_02077 9e-156 1.6.5.2 GM NmrA-like family
MKDMMHLC_02078 0.0 treB 2.7.1.193, 2.7.1.211 G phosphotransferase system
MKDMMHLC_02079 3.9e-127 magIII L Base excision DNA repair protein, HhH-GPD family
MKDMMHLC_02080 1.4e-08
MKDMMHLC_02081 1.1e-77 S NADPH-dependent FMN reductase
MKDMMHLC_02082 7.9e-238 S module of peptide synthetase
MKDMMHLC_02083 8.4e-105
MKDMMHLC_02084 1.3e-87 perR P Belongs to the Fur family
MKDMMHLC_02085 7.1e-59 S Enterocin A Immunity
MKDMMHLC_02086 5.4e-36 S Phospholipase_D-nuclease N-terminal
MKDMMHLC_02087 2.1e-60 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
MKDMMHLC_02088 2.1e-78 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
MKDMMHLC_02089 3.8e-104 J Acetyltransferase (GNAT) domain
MKDMMHLC_02090 5.1e-64 lrgA S LrgA family
MKDMMHLC_02091 7.3e-127 lrgB M LrgB-like family
MKDMMHLC_02092 7.1e-145 DegV S EDD domain protein, DegV family
MKDMMHLC_02093 4.1e-25
MKDMMHLC_02094 5e-117 yugP S Putative neutral zinc metallopeptidase
MKDMMHLC_02095 1.1e-294 crtI 1.3.99.26, 1.3.99.28, 1.3.99.29, 1.3.99.31 Q Flavin containing amine oxidoreductase
MKDMMHLC_02096 6.9e-164 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I Squalene/phytoene synthase
MKDMMHLC_02097 4.2e-183 D Alpha beta
MKDMMHLC_02098 2.9e-199 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MKDMMHLC_02099 1.9e-258 gor 1.8.1.7 C Glutathione reductase
MKDMMHLC_02100 9.8e-55 S Enterocin A Immunity
MKDMMHLC_02101 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MKDMMHLC_02102 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MKDMMHLC_02103 1.3e-184 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKDMMHLC_02104 1.7e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
MKDMMHLC_02105 4e-278 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MKDMMHLC_02107 2.1e-82
MKDMMHLC_02108 2.3e-257 yhdG E C-terminus of AA_permease
MKDMMHLC_02110 0.0 kup P Transport of potassium into the cell
MKDMMHLC_02111 4.6e-166 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MKDMMHLC_02112 5.3e-179 K AI-2E family transporter
MKDMMHLC_02113 1.3e-215 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
MKDMMHLC_02114 5.8e-59 qacC P Small Multidrug Resistance protein
MKDMMHLC_02115 1.1e-44 qacH U Small Multidrug Resistance protein
MKDMMHLC_02116 3e-116 hly S protein, hemolysin III
MKDMMHLC_02117 5.1e-54 nmtR K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_02118 2.7e-160 czcD P cation diffusion facilitator family transporter
MKDMMHLC_02119 2.6e-19
MKDMMHLC_02120 6.5e-96 tag 3.2.2.20 L glycosylase
MKDMMHLC_02121 2.3e-212 folP 2.5.1.15 H dihydropteroate synthase
MKDMMHLC_02122 7.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MKDMMHLC_02123 1.8e-248 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MKDMMHLC_02124 2.6e-103 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MKDMMHLC_02125 2.8e-93 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MKDMMHLC_02126 2.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MKDMMHLC_02127 4.7e-83 cvpA S Colicin V production protein
MKDMMHLC_02128 2e-169 znuA P Belongs to the bacterial solute-binding protein 9 family
MKDMMHLC_02129 1.3e-249 EGP Major facilitator Superfamily
MKDMMHLC_02131 7e-40
MKDMMHLC_02132 2.1e-244 dinF V MatE
MKDMMHLC_02133 1.9e-31
MKDMMHLC_02135 1.5e-77 elaA S Acetyltransferase (GNAT) domain
MKDMMHLC_02136 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MKDMMHLC_02137 1.4e-81
MKDMMHLC_02138 0.0 yhcA V MacB-like periplasmic core domain
MKDMMHLC_02139 1.1e-105
MKDMMHLC_02140 0.0 K PRD domain
MKDMMHLC_02141 2.4e-62 S Domain of unknown function (DUF3284)
MKDMMHLC_02142 1.4e-51 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MKDMMHLC_02143 1.1e-47 pts15B 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_02144 8.4e-214 pts15C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02145 5.2e-289 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02146 9.5e-209 EGP Major facilitator Superfamily
MKDMMHLC_02147 1.5e-112 M ErfK YbiS YcfS YnhG
MKDMMHLC_02148 4e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MKDMMHLC_02149 2.4e-283 ydfD K Alanine-glyoxylate amino-transferase
MKDMMHLC_02150 1.4e-102 argO S LysE type translocator
MKDMMHLC_02151 7.1e-214 arcT 2.6.1.1 E Aminotransferase
MKDMMHLC_02152 4.4e-77 argR K Regulates arginine biosynthesis genes
MKDMMHLC_02153 2.9e-12
MKDMMHLC_02154 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MKDMMHLC_02155 1e-54 yheA S Belongs to the UPF0342 family
MKDMMHLC_02156 5.7e-233 yhaO L Ser Thr phosphatase family protein
MKDMMHLC_02157 0.0 L AAA domain
MKDMMHLC_02158 2.9e-187 yhaM S Metal dependent phosphohydrolases with conserved 'HD' motif.
MKDMMHLC_02159 2.1e-213
MKDMMHLC_02160 3.1e-181 3.4.21.102 M Peptidase family S41
MKDMMHLC_02161 7.6e-177 K LysR substrate binding domain
MKDMMHLC_02162 2.1e-111 1.3.5.4 S NADPH-dependent FMN reductase
MKDMMHLC_02163 0.0 1.3.5.4 C FAD binding domain
MKDMMHLC_02164 1.7e-99
MKDMMHLC_02165 3.5e-76 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
MKDMMHLC_02166 6.1e-185 ykoT GT2 M Glycosyl transferase family 2
MKDMMHLC_02167 1.7e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKDMMHLC_02168 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MKDMMHLC_02169 1.7e-19 S NUDIX domain
MKDMMHLC_02170 0.0 S membrane
MKDMMHLC_02171 3.7e-172 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MKDMMHLC_02172 6.3e-75 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MKDMMHLC_02173 9e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MKDMMHLC_02174 1.4e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MKDMMHLC_02175 9.3e-106 GBS0088 S Nucleotidyltransferase
MKDMMHLC_02176 5.5e-106
MKDMMHLC_02177 7.9e-117 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
MKDMMHLC_02178 4.7e-74 K Bacterial regulatory proteins, tetR family
MKDMMHLC_02179 2.4e-65 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MKDMMHLC_02180 3.2e-43 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MKDMMHLC_02181 0.0 ctpA 3.6.3.54 P P-type ATPase
MKDMMHLC_02182 5.4e-214 adhC 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MKDMMHLC_02183 1.3e-223 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MKDMMHLC_02184 1.1e-65 lysM M LysM domain
MKDMMHLC_02185 9.6e-267 yjeM E Amino Acid
MKDMMHLC_02186 4.3e-144 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_02187 7.4e-71
MKDMMHLC_02189 7.7e-163 IQ KR domain
MKDMMHLC_02190 7.1e-228 amd 3.5.1.47 E Peptidase family M20/M25/M40
MKDMMHLC_02192 6.2e-310 XK27_09600 V ABC transporter, ATP-binding protein
MKDMMHLC_02193 0.0 V ABC transporter
MKDMMHLC_02194 8.6e-218 ykiI
MKDMMHLC_02195 2.1e-285 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MKDMMHLC_02196 1.2e-73 S Psort location Cytoplasmic, score
MKDMMHLC_02197 3.3e-219 T diguanylate cyclase
MKDMMHLC_02198 2e-120 tag 3.2.2.20 L Methyladenine glycosylase
MKDMMHLC_02199 4.2e-92
MKDMMHLC_02200 9.1e-164 psaA P Belongs to the bacterial solute-binding protein 9 family
MKDMMHLC_02201 1.8e-54 nudA S ASCH
MKDMMHLC_02202 1.8e-107 S SdpI/YhfL protein family
MKDMMHLC_02203 6.7e-87 M Lysin motif
MKDMMHLC_02204 2.3e-65 M LysM domain
MKDMMHLC_02205 5.1e-75 K helix_turn_helix, mercury resistance
MKDMMHLC_02206 5.3e-184 1.1.1.219 GM Male sterility protein
MKDMMHLC_02207 9.2e-280 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02208 3.5e-269 pts23C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02209 7e-53 ptcB 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_02210 6.8e-75 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKDMMHLC_02211 5.3e-150 dicA K Helix-turn-helix domain
MKDMMHLC_02212 3.2e-55
MKDMMHLC_02213 1.3e-159 T Calcineurin-like phosphoesterase superfamily domain
MKDMMHLC_02214 7.4e-64
MKDMMHLC_02215 0.0 P Concanavalin A-like lectin/glucanases superfamily
MKDMMHLC_02216 0.0 yhcA V ABC transporter, ATP-binding protein
MKDMMHLC_02217 1.2e-95 cadD P Cadmium resistance transporter
MKDMMHLC_02218 2e-49 K Transcriptional regulator, ArsR family
MKDMMHLC_02219 1.9e-116 S SNARE associated Golgi protein
MKDMMHLC_02220 1.1e-46
MKDMMHLC_02221 6.8e-72 T Belongs to the universal stress protein A family
MKDMMHLC_02222 4.1e-284 mntH P H( )-stimulated, divalent metal cation uptake system
MKDMMHLC_02223 6.1e-122 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_02224 2.8e-82 gtrA S GtrA-like protein
MKDMMHLC_02225 6.6e-113 zmp3 O Zinc-dependent metalloprotease
MKDMMHLC_02226 4.4e-35 yyaN K MerR HTH family regulatory protein
MKDMMHLC_02227 1.7e-120 azlC E branched-chain amino acid
MKDMMHLC_02228 9.4e-50 azlD S Branched-chain amino acid transport protein (AzlD)
MKDMMHLC_02229 0.0 asnB 6.3.5.4 E Asparagine synthase
MKDMMHLC_02230 1e-218 dapG 1.1.1.3, 2.7.2.4 E Amino acid kinase family
MKDMMHLC_02231 1.5e-280 murE 6.3.2.10, 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MKDMMHLC_02232 1e-254 xylP2 G symporter
MKDMMHLC_02233 2.6e-191 nlhH_1 I alpha/beta hydrolase fold
MKDMMHLC_02234 5.6e-49
MKDMMHLC_02235 3.2e-121 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
MKDMMHLC_02236 2e-91 3.2.2.20 K FR47-like protein
MKDMMHLC_02237 3.4e-127 yibF S overlaps another CDS with the same product name
MKDMMHLC_02238 1.4e-218 yibE S overlaps another CDS with the same product name
MKDMMHLC_02239 3.9e-179
MKDMMHLC_02240 5.6e-138 S NADPH-dependent FMN reductase
MKDMMHLC_02241 1.5e-50 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_02242 3.4e-163 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MKDMMHLC_02243 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
MKDMMHLC_02244 4.1e-32 L leucine-zipper of insertion element IS481
MKDMMHLC_02245 8.5e-41
MKDMMHLC_02246 1.7e-221 2.7.7.7, 3.6.4.12 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MKDMMHLC_02247 6.7e-278 pipD E Dipeptidase
MKDMMHLC_02248 9.9e-199 asnA 6.3.1.1 F aspartate--ammonia ligase
MKDMMHLC_02249 5.6e-255 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MKDMMHLC_02250 4.2e-115 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MKDMMHLC_02251 2.3e-81 rmaD K Transcriptional regulator
MKDMMHLC_02253 1.3e-210 1.3.5.4 C FMN_bind
MKDMMHLC_02254 1.2e-97 1.3.5.4 C FMN_bind
MKDMMHLC_02255 2.8e-171 K Transcriptional regulator
MKDMMHLC_02256 5.2e-41 K Helix-turn-helix domain
MKDMMHLC_02257 7.2e-47 K Helix-turn-helix domain
MKDMMHLC_02258 2.3e-139 K sequence-specific DNA binding
MKDMMHLC_02259 6.5e-87 S AAA domain
MKDMMHLC_02261 2.6e-186 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
MKDMMHLC_02262 1e-298 nagH 2.7.13.3, 3.2.1.4, 3.2.1.52, 3.2.1.78, 3.2.1.8 GH20,GH26,GH5,GH9 M MucBP domain
MKDMMHLC_02263 5.5e-92 XK27_09665 5.4.2.11 G Phosphoglycerate mutase family
MKDMMHLC_02264 1.7e-46 3.1.21.3 V Type I restriction modification DNA specificity domain
MKDMMHLC_02265 2.7e-171 L Belongs to the 'phage' integrase family
MKDMMHLC_02266 1.6e-67 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
MKDMMHLC_02267 1.7e-151 hsdM 2.1.1.72 V type I restriction-modification system
MKDMMHLC_02268 3.7e-95 hsdM 2.1.1.72 V type I restriction-modification system
MKDMMHLC_02269 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MKDMMHLC_02270 1.6e-106 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MKDMMHLC_02271 7.5e-89 pts21A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
MKDMMHLC_02272 5.6e-39 S Cytochrome B5
MKDMMHLC_02273 1.2e-234
MKDMMHLC_02274 7e-130 treR K UTRA
MKDMMHLC_02275 1.1e-158 I alpha/beta hydrolase fold
MKDMMHLC_02276 1.6e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
MKDMMHLC_02277 2e-233 yxiO S Vacuole effluxer Atg22 like
MKDMMHLC_02278 1.2e-171 ropB K Helix-turn-helix XRE-family like proteins
MKDMMHLC_02279 3.1e-207 EGP Major facilitator Superfamily
MKDMMHLC_02280 0.0 uvrA3 L excinuclease ABC
MKDMMHLC_02281 0.0 S Predicted membrane protein (DUF2207)
MKDMMHLC_02282 2.8e-148 3.1.3.102, 3.1.3.104 S hydrolase
MKDMMHLC_02283 1.2e-307 ybiT S ABC transporter, ATP-binding protein
MKDMMHLC_02284 1.1e-223 S CAAX protease self-immunity
MKDMMHLC_02285 2.2e-96 2.3.1.128 J Acetyltransferase (GNAT) domain
MKDMMHLC_02286 6.3e-99 speG J Acetyltransferase (GNAT) domain
MKDMMHLC_02287 1.7e-139 endA F DNA RNA non-specific endonuclease
MKDMMHLC_02288 1.4e-53 K helix_turn_helix, Arsenical Resistance Operon Repressor
MKDMMHLC_02289 1.5e-95 K Transcriptional regulator (TetR family)
MKDMMHLC_02290 1e-197 yhgE V domain protein
MKDMMHLC_02295 1.3e-246 EGP Major facilitator Superfamily
MKDMMHLC_02296 0.0 mdlA V ABC transporter
MKDMMHLC_02297 0.0 mdlB V ABC transporter
MKDMMHLC_02299 1.2e-194 C Aldo/keto reductase family
MKDMMHLC_02300 7.4e-102 M Protein of unknown function (DUF3737)
MKDMMHLC_02301 4.8e-221 patB 4.4.1.8 E Aminotransferase, class I
MKDMMHLC_02302 3.9e-102 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
MKDMMHLC_02303 3e-252 dtpT U amino acid peptide transporter
MKDMMHLC_02304 1.3e-150 yjjH S Calcineurin-like phosphoesterase
MKDMMHLC_02308 1.2e-49 5.3.3.19 S Cupin 2, conserved barrel domain protein
MKDMMHLC_02309 2.5e-53 S Cupin domain
MKDMMHLC_02310 1.6e-165 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
MKDMMHLC_02311 4.7e-194 ybiR P Citrate transporter
MKDMMHLC_02312 1.6e-151 pnuC H nicotinamide mononucleotide transporter
MKDMMHLC_02313 3.8e-137 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MKDMMHLC_02314 6.1e-221 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
MKDMMHLC_02315 1.6e-123 gntR1 K UbiC transcription regulator-associated domain protein
MKDMMHLC_02316 8.7e-136 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
MKDMMHLC_02317 5.2e-289 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MKDMMHLC_02318 1.4e-153 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MKDMMHLC_02319 0.0 pacL 3.6.3.8 P P-type ATPase
MKDMMHLC_02320 3.4e-71
MKDMMHLC_02321 0.0 yhgF K Tex-like protein N-terminal domain protein
MKDMMHLC_02322 3.7e-81 ydcK S Belongs to the SprT family
MKDMMHLC_02323 4e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
MKDMMHLC_02324 2.9e-154 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
MKDMMHLC_02326 7.4e-152 G Peptidase_C39 like family
MKDMMHLC_02327 1.3e-168 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
MKDMMHLC_02328 3.4e-133 manY G PTS system
MKDMMHLC_02329 4.4e-169 manN G system, mannose fructose sorbose family IID component
MKDMMHLC_02330 4.7e-64 S Domain of unknown function (DUF956)
MKDMMHLC_02331 0.0 levR K Sigma-54 interaction domain
MKDMMHLC_02332 4.3e-71 pts10A 2.7.1.191 G PTS system fructose IIA component
MKDMMHLC_02333 3.1e-87 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
MKDMMHLC_02334 5.4e-178 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MKDMMHLC_02335 9.7e-65 accB 2.3.1.12 I Biotin-requiring enzyme
MKDMMHLC_02336 1.5e-247 accC2 6.3.4.14, 6.4.1.2 I Biotin carboxylase C-terminal domain
MKDMMHLC_02337 8.3e-140 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MKDMMHLC_02338 4.3e-133 accA 2.1.3.15, 6.4.1.2 I Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit
MKDMMHLC_02339 5.3e-167 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MKDMMHLC_02340 5.6e-167 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
MKDMMHLC_02341 8.3e-177 EG EamA-like transporter family
MKDMMHLC_02342 9.5e-129 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKDMMHLC_02343 2.2e-129 S CAAX protease self-immunity
MKDMMHLC_02344 2.4e-22 plnF
MKDMMHLC_02345 5.5e-13
MKDMMHLC_02346 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MKDMMHLC_02347 7.5e-242 mesE M Transport protein ComB
MKDMMHLC_02348 1.4e-108 S CAAX protease self-immunity
MKDMMHLC_02349 7.4e-118 ypbD S CAAX protease self-immunity
MKDMMHLC_02350 1.2e-110 V CAAX protease self-immunity
MKDMMHLC_02351 9.6e-113 S CAAX protease self-immunity
MKDMMHLC_02352 1.8e-47 higA K Helix-turn-helix XRE-family like proteins
MKDMMHLC_02353 0.0 helD 3.6.4.12 L DNA helicase
MKDMMHLC_02354 2.1e-140 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MKDMMHLC_02355 5.9e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MKDMMHLC_02356 9e-130 K UbiC transcription regulator-associated domain protein
MKDMMHLC_02357 1.9e-253 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02358 3.9e-24
MKDMMHLC_02359 4.9e-75 S Domain of unknown function (DUF3284)
MKDMMHLC_02360 4.8e-34
MKDMMHLC_02361 2.8e-58 chpA T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKDMMHLC_02362 8.9e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKDMMHLC_02363 8.2e-168 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MKDMMHLC_02364 4e-229 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MKDMMHLC_02365 2.7e-177
MKDMMHLC_02366 2.5e-132 cobB K SIR2 family
MKDMMHLC_02367 2e-160 yunF F Protein of unknown function DUF72
MKDMMHLC_02368 5.2e-71 mutT 3.6.1.55 F DNA mismatch repair protein MutT
MKDMMHLC_02369 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MKDMMHLC_02370 2e-214 bcr1 EGP Major facilitator Superfamily
MKDMMHLC_02371 1.3e-83 mutR K sequence-specific DNA binding
MKDMMHLC_02373 1.5e-146 tatD L hydrolase, TatD family
MKDMMHLC_02374 4.7e-97 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MKDMMHLC_02375 1.5e-158 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MKDMMHLC_02376 3.2e-37 veg S Biofilm formation stimulator VEG
MKDMMHLC_02377 1.5e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MKDMMHLC_02378 1.3e-181 S Prolyl oligopeptidase family
MKDMMHLC_02379 9.8e-129 fhuC 3.6.3.35 P ABC transporter
MKDMMHLC_02380 9.2e-131 znuB U ABC 3 transport family
MKDMMHLC_02381 2e-45 ygbF S Sugar efflux transporter for intercellular exchange
MKDMMHLC_02382 4.1e-169 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MKDMMHLC_02383 0.0 rafA 3.2.1.22 G alpha-galactosidase
MKDMMHLC_02384 0.0 scrA 2.7.1.193, 2.7.1.211, 5.3.1.1 G phosphotransferase system
MKDMMHLC_02385 1.5e-304 scrB 3.2.1.26 GH32 G invertase
MKDMMHLC_02386 5.9e-172 scrR K Transcriptional regulator, LacI family
MKDMMHLC_02387 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MKDMMHLC_02388 1.4e-164 3.5.1.10 C nadph quinone reductase
MKDMMHLC_02389 1.1e-217 nhaC C Na H antiporter NhaC
MKDMMHLC_02390 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MKDMMHLC_02391 2.9e-128 mleR K LysR substrate binding domain
MKDMMHLC_02392 5e-27 mleR K LysR substrate binding domain
MKDMMHLC_02393 0.0 3.6.4.13 M domain protein
MKDMMHLC_02395 2.1e-157 hipB K Helix-turn-helix
MKDMMHLC_02396 0.0 oppA E ABC transporter, substratebinding protein
MKDMMHLC_02397 1.8e-309 oppA E ABC transporter, substratebinding protein
MKDMMHLC_02398 5.9e-79 yiaC K Acetyltransferase (GNAT) domain
MKDMMHLC_02399 2.3e-215 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MKDMMHLC_02400 7e-203 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
MKDMMHLC_02401 3e-113 pgm1 G phosphoglycerate mutase
MKDMMHLC_02402 7.2e-178 yghZ C Aldo keto reductase family protein
MKDMMHLC_02403 4.9e-34
MKDMMHLC_02404 1.3e-60 S Domain of unknown function (DU1801)
MKDMMHLC_02405 2.9e-162 FbpA K Domain of unknown function (DUF814)
MKDMMHLC_02406 4.5e-219 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKDMMHLC_02408 3.5e-58 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDMMHLC_02409 8.5e-50 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MKDMMHLC_02410 2.6e-212 S ATPases associated with a variety of cellular activities
MKDMMHLC_02411 2.9e-253 S Bacterial membrane protein YfhO
MKDMMHLC_02412 1.6e-146 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_02413 2.1e-168 K LysR substrate binding domain
MKDMMHLC_02414 1.9e-236 EK Aminotransferase, class I
MKDMMHLC_02415 2.3e-126 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MKDMMHLC_02416 8.1e-123 tcyB E ABC transporter
MKDMMHLC_02417 3.6e-137 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_02418 3.3e-120 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MKDMMHLC_02419 5.8e-79 KT response to antibiotic
MKDMMHLC_02420 9.8e-52 K Transcriptional regulator
MKDMMHLC_02421 7.7e-72 XK27_06920 S Protein of unknown function (DUF1700)
MKDMMHLC_02422 2.1e-126 S Putative adhesin
MKDMMHLC_02423 0.0 scrA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MKDMMHLC_02424 0.0 malA 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MKDMMHLC_02425 4.1e-181 5.1.1.1 K Periplasmic binding proteins and sugar binding domain of LacI family
MKDMMHLC_02426 2.6e-205 S DUF218 domain
MKDMMHLC_02427 6.8e-128 ybbM S Uncharacterised protein family (UPF0014)
MKDMMHLC_02428 1.4e-116 ybbL S ABC transporter, ATP-binding protein
MKDMMHLC_02429 4.2e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MKDMMHLC_02430 9.4e-77
MKDMMHLC_02431 2.2e-151 qorB 1.6.5.2 GM NmrA-like family
MKDMMHLC_02432 1.1e-147 cof S haloacid dehalogenase-like hydrolase
MKDMMHLC_02433 3.7e-93 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MKDMMHLC_02434 4e-308 mngB 3.2.1.170, 3.2.1.24 GH38 G Glycosyl hydrolases family 38 N-terminal domain
MKDMMHLC_02435 3.7e-122 mngA 2.7.1.195, 2.7.1.202 U Phosphotransferase system, EIIC
MKDMMHLC_02436 2.4e-26 mngA 2.7.1.195, 2.7.1.202 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_02437 1.7e-20 fryA 2.7.1.202 G COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
MKDMMHLC_02438 2.9e-90 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKDMMHLC_02439 7e-33
MKDMMHLC_02441 5.4e-212 livJ E Receptor family ligand binding region
MKDMMHLC_02442 2.1e-149 livH U Branched-chain amino acid transport system / permease component
MKDMMHLC_02443 5.3e-141 livM E Branched-chain amino acid transport system / permease component
MKDMMHLC_02444 5.2e-139 livG E Branched-chain amino acid ATP-binding cassette transporter
MKDMMHLC_02445 3.3e-124 livF E ABC transporter
MKDMMHLC_02446 1.8e-31 cp12 S Domain in cystathionine beta-synthase and other proteins.
MKDMMHLC_02447 5.3e-63 acuB S Domain in cystathionine beta-synthase and other proteins.
MKDMMHLC_02448 2.3e-91 S WxL domain surface cell wall-binding
MKDMMHLC_02449 2.5e-189 S Cell surface protein
MKDMMHLC_02450 7.3e-62
MKDMMHLC_02451 1e-260
MKDMMHLC_02452 1.5e-167 XK27_00670 S ABC transporter
MKDMMHLC_02453 5.6e-154 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
MKDMMHLC_02454 2.9e-117 cmpC S ATPases associated with a variety of cellular activities
MKDMMHLC_02455 0.0 nagE 2.7.1.193, 2.7.1.199, 2.7.1.211 G phosphotransferase system, EIIB
MKDMMHLC_02456 1.3e-119 drgA C Nitroreductase family
MKDMMHLC_02457 3e-121 yceE S haloacid dehalogenase-like hydrolase
MKDMMHLC_02458 7.1e-159 ccpB 5.1.1.1 K lacI family
MKDMMHLC_02459 5e-93 rmaB K Transcriptional regulator, MarR family
MKDMMHLC_02460 2.4e-187 lmrA 3.6.3.44 V ABC transporter
MKDMMHLC_02461 7.6e-132 lmrA 3.6.3.44 V ABC transporter
MKDMMHLC_02462 5.6e-89
MKDMMHLC_02463 0.0 ybfG M peptidoglycan-binding domain-containing protein
MKDMMHLC_02464 4.2e-161 ypbG 2.7.1.2 GK ROK family
MKDMMHLC_02465 6.9e-47 3.6.4.12 K HxlR-like helix-turn-helix
MKDMMHLC_02466 2.5e-112 K Transcriptional regulator C-terminal region
MKDMMHLC_02467 1.7e-176 4.1.1.52 S Amidohydrolase
MKDMMHLC_02468 1.3e-128 E lipolytic protein G-D-S-L family
MKDMMHLC_02469 1.1e-159 yicL EG EamA-like transporter family
MKDMMHLC_02470 9.1e-50
MKDMMHLC_02471 3e-08
MKDMMHLC_02473 5.2e-188 rbsR K helix_turn _helix lactose operon repressor
MKDMMHLC_02474 6.7e-162 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MKDMMHLC_02475 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MKDMMHLC_02476 2.7e-160 rbsU U ribose uptake protein RbsU
MKDMMHLC_02477 3.8e-145 IQ NAD dependent epimerase/dehydratase family
MKDMMHLC_02478 0.0 srlM 2.7.1.194, 2.7.1.200, 2.7.1.202 GKT Mga helix-turn-helix domain
MKDMMHLC_02479 1.1e-86 gutM K Glucitol operon activator protein (GutM)
MKDMMHLC_02480 2e-100 srlA G PTS system enzyme II sorbitol-specific factor
MKDMMHLC_02481 1.5e-173 srlE 2.7.1.198 G Sorbitol phosphotransferase enzyme II N-terminus
MKDMMHLC_02482 8.6e-63 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MKDMMHLC_02483 0.0 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKDMMHLC_02484 8.7e-72 K Transcriptional regulator
MKDMMHLC_02485 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
MKDMMHLC_02486 1.1e-130 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MKDMMHLC_02487 5.1e-57 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
MKDMMHLC_02489 0.0 clpL O C-terminal, D2-small domain, of ClpB protein
MKDMMHLC_02490 2.4e-67 agrB KOT May be involved in the proteolytic processing of a quorum sensing system signal molecule precursor
MKDMMHLC_02491 1.8e-12
MKDMMHLC_02492 8.7e-160 2.7.13.3 T GHKL domain
MKDMMHLC_02493 7.4e-135 K LytTr DNA-binding domain
MKDMMHLC_02494 4.9e-78 yneH 1.20.4.1 K ArsC family
MKDMMHLC_02495 5.4e-291 katA 1.11.1.6 C Belongs to the catalase family
MKDMMHLC_02496 9e-13 ytgB S Transglycosylase associated protein
MKDMMHLC_02497 3.6e-11
MKDMMHLC_02498 1.6e-89 folT 2.7.13.3 T ECF transporter, substrate-specific component
MKDMMHLC_02499 2.4e-114 K UTRA
MKDMMHLC_02500 1.2e-269 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02501 1.6e-247 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02502 4.1e-65
MKDMMHLC_02503 6.4e-63 S Protein of unknown function (DUF1093)
MKDMMHLC_02504 4.3e-207 S Membrane
MKDMMHLC_02505 1.1e-43 S Protein of unknown function (DUF3781)
MKDMMHLC_02506 1e-107 ydeA S intracellular protease amidase
MKDMMHLC_02507 2.2e-41 K HxlR-like helix-turn-helix
MKDMMHLC_02508 3.3e-66
MKDMMHLC_02509 1e-64 V ABC transporter
MKDMMHLC_02510 2.3e-51 K Helix-turn-helix domain
MKDMMHLC_02511 1.6e-202 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MKDMMHLC_02512 1.4e-46 K Helix-turn-helix domain
MKDMMHLC_02513 1.2e-90 S ABC-2 family transporter protein
MKDMMHLC_02514 5.7e-58 S ABC-2 family transporter protein
MKDMMHLC_02515 4.6e-91 V ABC transporter, ATP-binding protein
MKDMMHLC_02516 8.8e-40
MKDMMHLC_02517 7.9e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MKDMMHLC_02518 4.9e-172 K AI-2E family transporter
MKDMMHLC_02519 1.7e-210 xylR GK ROK family
MKDMMHLC_02520 2.3e-81
MKDMMHLC_02521 4.7e-232 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MKDMMHLC_02522 3.9e-162
MKDMMHLC_02523 3.2e-200 KLT Protein tyrosine kinase
MKDMMHLC_02524 2.9e-23 S Protein of unknown function (DUF4064)
MKDMMHLC_02525 6e-97 S Domain of unknown function (DUF4352)
MKDMMHLC_02526 3.9e-75 S Psort location Cytoplasmic, score
MKDMMHLC_02527 3.4e-171 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02528 1.3e-154 licT K CAT RNA binding domain
MKDMMHLC_02529 0.0 pts30BCA 2.7.1.193, 2.7.1.211 G phosphotransferase system
MKDMMHLC_02530 1.4e-291 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02531 1.1e-211 S Bacterial protein of unknown function (DUF871)
MKDMMHLC_02532 2.2e-157 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
MKDMMHLC_02533 4.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
MKDMMHLC_02534 6.2e-249 pts29C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02535 1.2e-134 K UTRA domain
MKDMMHLC_02536 3.4e-154 estA S Putative esterase
MKDMMHLC_02537 1e-63
MKDMMHLC_02538 1.8e-210 ydiN G Major Facilitator Superfamily
MKDMMHLC_02539 3.4e-163 K Transcriptional regulator, LysR family
MKDMMHLC_02540 4.2e-169 aroE 1.1.1.25, 1.1.1.282, 1.3.5.4 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MKDMMHLC_02541 2.7e-214 ydiM G Transporter
MKDMMHLC_02542 2.1e-129 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
MKDMMHLC_02543 4.8e-179 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKDMMHLC_02544 0.0 1.3.5.4 C FAD binding domain
MKDMMHLC_02545 5.2e-65 S pyridoxamine 5-phosphate
MKDMMHLC_02546 3.1e-192 C Aldo keto reductase family protein
MKDMMHLC_02547 1.1e-173 galR K Transcriptional regulator
MKDMMHLC_02548 4.5e-199 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MKDMMHLC_02549 0.0 lacS G Transporter
MKDMMHLC_02550 1.3e-229 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
MKDMMHLC_02551 1.8e-122 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
MKDMMHLC_02552 6.2e-165 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
MKDMMHLC_02553 5.4e-153 nanK GK ROK family
MKDMMHLC_02554 1.6e-134 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
MKDMMHLC_02555 5.2e-207 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MKDMMHLC_02556 1.7e-271 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MKDMMHLC_02557 1.3e-159 I alpha/beta hydrolase fold
MKDMMHLC_02558 1.6e-99 I alpha/beta hydrolase fold
MKDMMHLC_02559 2.6e-38 I alpha/beta hydrolase fold
MKDMMHLC_02560 3.7e-72 yueI S Protein of unknown function (DUF1694)
MKDMMHLC_02561 7.4e-136 K Helix-turn-helix domain, rpiR family
MKDMMHLC_02562 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MKDMMHLC_02563 7e-112 K DeoR C terminal sensor domain
MKDMMHLC_02564 1.5e-80 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKDMMHLC_02565 1.1e-44 2.7.1.194, 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
MKDMMHLC_02566 1.1e-231 gatC G PTS system sugar-specific permease component
MKDMMHLC_02567 3e-188 gutB 1.1.1.1, 1.1.1.14 C Zinc-binding dehydrogenase
MKDMMHLC_02568 1.8e-113 gph 3.1.3.18 S Haloacid dehalogenase-like hydrolase
MKDMMHLC_02569 0.0 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKDMMHLC_02570 6.7e-78 2.7.1.194, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
MKDMMHLC_02571 2.2e-45 ulaB 2.7.1.194, 2.7.1.200 G Phosphotransferase system galactitol-specific IIB component
MKDMMHLC_02572 3.2e-240 ulaA 2.7.1.194 S PTS system sugar-specific permease component
MKDMMHLC_02573 8.3e-114 tal 2.2.1.2 F Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MKDMMHLC_02574 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MKDMMHLC_02575 4.3e-144 yxeH S hydrolase
MKDMMHLC_02576 3.4e-31 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKDMMHLC_02577 4.4e-25 S Immunity protein 74
MKDMMHLC_02578 5.1e-52 U domain, Protein
MKDMMHLC_02579 1.1e-235 M domain protein
MKDMMHLC_02580 4.7e-134 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MKDMMHLC_02581 0.0 glpD 1.1.3.21, 1.1.5.3 C C-terminal domain of alpha-glycerophosphate oxidase
MKDMMHLC_02582 1.3e-300 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MKDMMHLC_02583 2.6e-255 gshR 1.8.1.7 C Glutathione reductase
MKDMMHLC_02584 9.9e-180 proV E ABC transporter, ATP-binding protein
MKDMMHLC_02585 1.5e-275 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
MKDMMHLC_02586 3.8e-78 3.1.26.4 L RNA-DNA hybrid ribonuclease activity
MKDMMHLC_02587 3.9e-162 vdlC S Belongs to the short-chain dehydrogenases reductases (SDR) family
MKDMMHLC_02588 4.5e-174 rihC 3.2.2.1 F Nucleoside
MKDMMHLC_02589 2.7e-68 accB 2.3.1.12 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
MKDMMHLC_02590 9.3e-80
MKDMMHLC_02591 9.3e-83 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
MKDMMHLC_02592 1.5e-230 flhF N Uncharacterized conserved protein (DUF2075)
MKDMMHLC_02593 8.8e-95 yxkA S Phosphatidylethanolamine-binding protein
MKDMMHLC_02594 1.1e-54 ypaA S Protein of unknown function (DUF1304)
MKDMMHLC_02595 4.2e-310 mco Q Multicopper oxidase
MKDMMHLC_02596 4.6e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
MKDMMHLC_02597 3.2e-20 zmp1 O Zinc-dependent metalloprotease
MKDMMHLC_02598 3.7e-44
MKDMMHLC_02599 4.5e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MKDMMHLC_02600 2.9e-131 ydfG S KR domain
MKDMMHLC_02601 8.3e-63 hxlR K HxlR-like helix-turn-helix
MKDMMHLC_02602 1e-47 S Domain of unknown function (DUF1905)
MKDMMHLC_02603 0.0 M Glycosyl hydrolases family 25
MKDMMHLC_02604 9.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MKDMMHLC_02605 2e-166 GM NmrA-like family
MKDMMHLC_02606 1.5e-95 fadR K Bacterial regulatory proteins, tetR family
MKDMMHLC_02607 4.3e-204 2.7.13.3 T GHKL domain
MKDMMHLC_02608 8.2e-134 K LytTr DNA-binding domain
MKDMMHLC_02609 0.0 asnB 6.3.5.4 E Asparagine synthase
MKDMMHLC_02610 1.4e-94 M ErfK YbiS YcfS YnhG
MKDMMHLC_02611 5.1e-210 ytbD EGP Major facilitator Superfamily
MKDMMHLC_02612 2e-61 K Transcriptional regulator, HxlR family
MKDMMHLC_02613 1e-116 S Haloacid dehalogenase-like hydrolase
MKDMMHLC_02614 5.9e-117
MKDMMHLC_02615 6.9e-210 NU Mycoplasma protein of unknown function, DUF285
MKDMMHLC_02616 1.1e-62
MKDMMHLC_02617 2.2e-100 S WxL domain surface cell wall-binding
MKDMMHLC_02618 2.4e-187 S Cell surface protein
MKDMMHLC_02619 1.8e-113 S GyrI-like small molecule binding domain
MKDMMHLC_02620 1.3e-66 S Iron-sulphur cluster biosynthesis
MKDMMHLC_02621 2.3e-176 1.6.5.5 C Alcohol dehydrogenase GroES-like domain
MKDMMHLC_02629 5.5e-08
MKDMMHLC_02637 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MKDMMHLC_02638 2.2e-139 yhfI S Metallo-beta-lactamase superfamily
MKDMMHLC_02639 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MKDMMHLC_02640 2.2e-131 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MKDMMHLC_02641 2e-13 coiA 3.6.4.12 S Competence protein
MKDMMHLC_02642 2e-180 coiA 3.6.4.12 S Competence protein
MKDMMHLC_02643 0.0 pepF E oligoendopeptidase F
MKDMMHLC_02644 3.6e-114 yjbH Q Thioredoxin
MKDMMHLC_02645 6e-120 yjbM 2.7.6.5 S RelA SpoT domain protein
MKDMMHLC_02646 4.7e-151 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MKDMMHLC_02647 2.6e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MKDMMHLC_02648 1.1e-115 cutC P Participates in the control of copper homeostasis
MKDMMHLC_02649 1.3e-193 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MKDMMHLC_02650 3.9e-57 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
MKDMMHLC_02651 4.3e-206 XK27_05220 S AI-2E family transporter
MKDMMHLC_02652 1.7e-41 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MKDMMHLC_02653 5.6e-106 rrmA 2.1.1.187 H Methyltransferase
MKDMMHLC_02654 7.4e-32 rrmA 2.1.1.187 H Methyltransferase
MKDMMHLC_02656 4.8e-209 brnQ U Component of the transport system for branched-chain amino acids
MKDMMHLC_02657 2.4e-113 ywnB S NAD(P)H-binding
MKDMMHLC_02658 1.8e-95 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MKDMMHLC_02659 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MKDMMHLC_02660 4.8e-57 sdrF M Collagen binding domain
MKDMMHLC_02661 2.5e-269 I acetylesterase activity
MKDMMHLC_02662 2.6e-176 S Phosphotransferase system, EIIC
MKDMMHLC_02663 1.7e-15 aroD S Alpha/beta hydrolase family
MKDMMHLC_02664 8.3e-108 aroD S Alpha/beta hydrolase family
MKDMMHLC_02665 3.2e-37
MKDMMHLC_02667 2.8e-134 S zinc-ribbon domain
MKDMMHLC_02668 1.5e-264 S response to antibiotic
MKDMMHLC_02669 3.7e-287 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
MKDMMHLC_02670 2.4e-243 P Sodium:sulfate symporter transmembrane region
MKDMMHLC_02671 1.2e-163 K LysR substrate binding domain
MKDMMHLC_02672 2.9e-70
MKDMMHLC_02673 4.9e-22
MKDMMHLC_02674 5.8e-191 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MKDMMHLC_02675 2.6e-191 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MKDMMHLC_02676 4.5e-73 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MKDMMHLC_02677 2e-80
MKDMMHLC_02678 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MKDMMHLC_02679 3.2e-103 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKDMMHLC_02680 6.8e-127 yliE T EAL domain
MKDMMHLC_02681 1.2e-102 2.7.7.65 T Diguanylate cyclase, GGDEF domain
MKDMMHLC_02682 4.7e-241 amtB P ammonium transporter
MKDMMHLC_02683 1.3e-257 P Major Facilitator Superfamily
MKDMMHLC_02684 2.8e-91 K Transcriptional regulator PadR-like family
MKDMMHLC_02685 8.4e-44
MKDMMHLC_02686 1e-201 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
MKDMMHLC_02687 6e-154 tagG U Transport permease protein
MKDMMHLC_02688 3.8e-218
MKDMMHLC_02689 7.8e-222 mtnE 2.6.1.83 E Aminotransferase
MKDMMHLC_02690 1.8e-61 S CHY zinc finger
MKDMMHLC_02691 1.1e-175 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MKDMMHLC_02692 5.7e-95 bioY S BioY family
MKDMMHLC_02693 3e-40
MKDMMHLC_02694 6.5e-281 pipD E Dipeptidase
MKDMMHLC_02695 1.1e-29
MKDMMHLC_02696 8.7e-122 qmcA O prohibitin homologues
MKDMMHLC_02697 1.5e-239 xylP1 G MFS/sugar transport protein
MKDMMHLC_02699 2.8e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MKDMMHLC_02700 1.8e-256 adhE 1.1.1.1, 1.2.1.10 C Aldehyde dehydrogenase family
MKDMMHLC_02701 2.6e-30
MKDMMHLC_02702 5.2e-109 S membrane transporter protein
MKDMMHLC_02703 2.3e-54 azlD S branched-chain amino acid
MKDMMHLC_02704 5.1e-131 azlC E branched-chain amino acid
MKDMMHLC_02705 3.2e-89 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MKDMMHLC_02706 2.1e-236 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MKDMMHLC_02707 1.3e-213 hpk31 2.7.13.3 T Histidine kinase
MKDMMHLC_02708 3.2e-124 K response regulator
MKDMMHLC_02709 5.5e-124 yoaK S Protein of unknown function (DUF1275)
MKDMMHLC_02710 2.6e-161 prsA 3.1.3.16, 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MKDMMHLC_02711 5.2e-212 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MKDMMHLC_02712 5.2e-125 XK27_01040 S Protein of unknown function (DUF1129)
MKDMMHLC_02713 2e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MKDMMHLC_02714 9.8e-31 yyzM S Bacterial protein of unknown function (DUF951)
MKDMMHLC_02715 2.4e-156 spo0J K Belongs to the ParB family
MKDMMHLC_02716 1.8e-136 soj D Sporulation initiation inhibitor
MKDMMHLC_02717 7.9e-149 noc K Belongs to the ParB family
MKDMMHLC_02718 1.9e-130 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MKDMMHLC_02719 1.2e-225 nupG F Nucleoside
MKDMMHLC_02720 2.3e-219 S Bacterial membrane protein YfhO
MKDMMHLC_02722 2.3e-96 K Helix-turn-helix domain
MKDMMHLC_02723 2.5e-175 nsr 3.4.21.102 M Peptidase family S41
MKDMMHLC_02724 2.8e-21 L Transposase
MKDMMHLC_02725 2.6e-79
MKDMMHLC_02726 5.3e-19
MKDMMHLC_02727 0.0 O Belongs to the peptidase S8 family
MKDMMHLC_02729 1e-78 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
MKDMMHLC_02730 1e-174 tnp2 L PFAM Transposase, IS204 IS1001 IS1096 IS1165
MKDMMHLC_02731 2.6e-71 brnQ U Component of the transport system for branched-chain amino acids
MKDMMHLC_02732 0.0 lacS G Transporter
MKDMMHLC_02733 0.0 lacA 3.2.1.23 G -beta-galactosidase
MKDMMHLC_02734 1.2e-29
MKDMMHLC_02735 6.8e-10 K Helix-turn-helix XRE-family like proteins
MKDMMHLC_02736 4.8e-62 S Protein of unknown function (DUF2992)
MKDMMHLC_02737 3.2e-59 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MKDMMHLC_02738 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MKDMMHLC_02739 2.8e-105 L Integrase
MKDMMHLC_02740 6.1e-45 S Phage derived protein Gp49-like (DUF891)
MKDMMHLC_02741 1.7e-36 K sequence-specific DNA binding
MKDMMHLC_02742 1.1e-54 S Bacterial mobilisation protein (MobC)
MKDMMHLC_02743 1.6e-184 U Relaxase/Mobilisation nuclease domain
MKDMMHLC_02744 2.8e-55 repA S Replication initiator protein A
MKDMMHLC_02745 2.7e-42
MKDMMHLC_02746 0.0 pacL 3.6.3.8 P P-type ATPase
MKDMMHLC_02748 6.2e-44 S Psort location CytoplasmicMembrane, score
MKDMMHLC_02749 2.1e-20 3.4.21.19 M Belongs to the peptidase S1B family
MKDMMHLC_02750 8.3e-17 S Protein of unknown function (DUF1093)
MKDMMHLC_02751 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 S MucBP domain
MKDMMHLC_02752 4e-281 1.3.5.4 C FAD binding domain
MKDMMHLC_02753 1.8e-159 K LysR substrate binding domain
MKDMMHLC_02754 5.7e-152 nudC 1.3.7.1, 3.6.1.22 L NADH pyrophosphatase zinc ribbon domain
MKDMMHLC_02755 2.5e-289 yjcE P Sodium proton antiporter
MKDMMHLC_02756 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MKDMMHLC_02757 8.1e-117 K Bacterial regulatory proteins, tetR family
MKDMMHLC_02758 3.1e-51 NU Mycoplasma protein of unknown function, DUF285
MKDMMHLC_02760 4.2e-144 soj D AAA domain
MKDMMHLC_02761 5.2e-34
MKDMMHLC_02764 6.8e-127 tnp L DDE domain
MKDMMHLC_02765 2.6e-16
MKDMMHLC_02767 2.9e-38 sirR K Helix-turn-helix diphteria tox regulatory element
MKDMMHLC_02768 1.5e-249 mntH P H( )-stimulated, divalent metal cation uptake system
MKDMMHLC_02769 6.2e-57 T Belongs to the universal stress protein A family
MKDMMHLC_02770 1e-96 tnpR1 L Resolvase, N terminal domain
MKDMMHLC_02771 7.6e-55 K helix_turn_helix multiple antibiotic resistance protein
MKDMMHLC_02772 0.0 kup P Transport of potassium into the cell
MKDMMHLC_02773 4.9e-38 KT Transcriptional regulatory protein, C terminal
MKDMMHLC_02774 0.0 3.2.1.96 G Glycosyl hydrolase family 85
MKDMMHLC_02775 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MKDMMHLC_02776 4e-209 msmK P Belongs to the ABC transporter superfamily
MKDMMHLC_02777 5e-259 malS 3.2.1.1 GH13 G Glycogen debranching enzyme, glucanotransferase domain
MKDMMHLC_02778 1.6e-149 malA S maltodextrose utilization protein MalA
MKDMMHLC_02779 1.4e-161 malD P ABC transporter permease
MKDMMHLC_02780 2.2e-227 malC P Binding-protein-dependent transport system inner membrane component
MKDMMHLC_02781 4.2e-231 mdxE G Bacterial extracellular solute-binding protein
MKDMMHLC_02782 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MKDMMHLC_02783 2.3e-270 G Major Facilitator
MKDMMHLC_02784 1.1e-173 K Transcriptional regulator, LacI family
MKDMMHLC_02785 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
MKDMMHLC_02786 3.8e-159 licT K CAT RNA binding domain
MKDMMHLC_02787 0.0 bglP 2.7.1.193, 2.7.1.211 G phosphotransferase system
MKDMMHLC_02788 5.5e-291 pbg10 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
MKDMMHLC_02789 4.6e-25 S Cysteine-rich secretory protein family
MKDMMHLC_02790 1.1e-36 S MORN repeat
MKDMMHLC_02791 0.0 XK27_09800 I Acyltransferase family
MKDMMHLC_02792 7.1e-37 S Transglycosylase associated protein
MKDMMHLC_02793 4.4e-84
MKDMMHLC_02794 7.2e-23
MKDMMHLC_02795 8.7e-72 asp S Asp23 family, cell envelope-related function
MKDMMHLC_02796 5.3e-72 asp2 S Asp23 family, cell envelope-related function
MKDMMHLC_02797 2.6e-149 Q Fumarylacetoacetate (FAA) hydrolase family
MKDMMHLC_02798 1.5e-154 yjdB S Domain of unknown function (DUF4767)
MKDMMHLC_02799 3.4e-10 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIA subunit
MKDMMHLC_02800 1.1e-101 G Glycogen debranching enzyme
MKDMMHLC_02801 0.0 pepN 3.4.11.2 E aminopeptidase
MKDMMHLC_02802 7.3e-86 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MKDMMHLC_02803 2.4e-121 E GDSL-like Lipase/Acylhydrolase family
MKDMMHLC_02804 1.4e-77
MKDMMHLC_02805 8.1e-38 S Bacteriocin-protection, YdeI or OmpD-Associated
MKDMMHLC_02806 3.3e-97 FG HIT domain
MKDMMHLC_02807 1.7e-173 S Aldo keto reductase
MKDMMHLC_02808 1.9e-52 yitW S Pfam:DUF59
MKDMMHLC_02809 1.9e-160 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MKDMMHLC_02810 0.0 pflB 2.3.1.54 C Pyruvate formate lyase-like
MKDMMHLC_02811 5e-195 blaA6 V Beta-lactamase
MKDMMHLC_02812 6.2e-96 V VanZ like family
MKDMMHLC_02813 6e-140 K Helix-turn-helix domain
MKDMMHLC_02814 2.9e-38 S TfoX C-terminal domain
MKDMMHLC_02815 2.3e-227 hpk9 2.7.13.3 T GHKL domain
MKDMMHLC_02816 8.4e-263
MKDMMHLC_02817 8.4e-75
MKDMMHLC_02818 3.6e-183 S Cell surface protein
MKDMMHLC_02819 1.7e-101 S WxL domain surface cell wall-binding
MKDMMHLC_02820 2.2e-126
MKDMMHLC_02821 1.1e-184 S DUF218 domain
MKDMMHLC_02822 1.2e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MKDMMHLC_02823 1.2e-149 bla1 3.5.2.6 V Beta-lactamase enzyme family
MKDMMHLC_02824 3.9e-206 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MKDMMHLC_02825 6.6e-148 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MKDMMHLC_02826 2.1e-31
MKDMMHLC_02827 1.7e-43 ankB S ankyrin repeats
MKDMMHLC_02828 6.5e-91 S ECF-type riboflavin transporter, S component
MKDMMHLC_02829 4.2e-47
MKDMMHLC_02830 9.8e-214 yceI EGP Major facilitator Superfamily
MKDMMHLC_02831 1.9e-138 3.6.1.13, 3.6.1.55 F NUDIX domain
MKDMMHLC_02832 3.8e-23
MKDMMHLC_02834 4.1e-161 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_02835 8.2e-173 ykfC 3.4.14.13 M NlpC/P60 family
MKDMMHLC_02836 3.3e-80 K AsnC family
MKDMMHLC_02837 2e-35
MKDMMHLC_02838 3.3e-33
MKDMMHLC_02839 5.6e-217 2.7.7.65 T diguanylate cyclase
MKDMMHLC_02840 1e-106
MKDMMHLC_02841 1.4e-117 S Domain of unknown function (DUF4811)
MKDMMHLC_02842 7e-270 lmrB EGP Major facilitator Superfamily
MKDMMHLC_02843 1.7e-84 merR K MerR HTH family regulatory protein
MKDMMHLC_02844 2.6e-58
MKDMMHLC_02845 2e-120 sirR K iron dependent repressor
MKDMMHLC_02846 6e-31 cspC K Cold shock protein
MKDMMHLC_02847 1.5e-130 thrE S Putative threonine/serine exporter
MKDMMHLC_02848 2.2e-76 S Threonine/Serine exporter, ThrE
MKDMMHLC_02849 9.7e-155 glcU U sugar transport
MKDMMHLC_02850 9.4e-217 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
MKDMMHLC_02851 2.9e-287 yclK 2.7.13.3 T Histidine kinase
MKDMMHLC_02852 1.6e-134 K response regulator
MKDMMHLC_02853 3e-243 XK27_08635 S UPF0210 protein
MKDMMHLC_02854 2.3e-38 gcvR T Belongs to the UPF0237 family
MKDMMHLC_02855 2.6e-169 EG EamA-like transporter family
MKDMMHLC_02857 2.8e-88
MKDMMHLC_02858 2.9e-176 L Initiator Replication protein
MKDMMHLC_02859 2.5e-29
MKDMMHLC_02860 2.3e-107 L Integrase
MKDMMHLC_02861 2.4e-40 K prlF antitoxin for toxin YhaV_toxin
MKDMMHLC_02862 5.3e-59 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKDMMHLC_02863 0.0 ybfG M peptidoglycan-binding domain-containing protein
MKDMMHLC_02865 7.6e-110 XK27_07075 V CAAX protease self-immunity
MKDMMHLC_02866 1.1e-56 hxlR K HxlR-like helix-turn-helix
MKDMMHLC_02867 1.5e-129 L Helix-turn-helix domain
MKDMMHLC_02868 1.7e-159 L hmm pf00665
MKDMMHLC_02869 6.7e-232 EGP Major facilitator Superfamily
MKDMMHLC_02870 2e-132 S Cysteine-rich secretory protein family
MKDMMHLC_02871 1.4e-67 M Cna protein B-type domain
MKDMMHLC_02872 3.2e-256 ykgC 1.16.1.1, 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MKDMMHLC_02873 7.5e-158 traA L MobA MobL family protein
MKDMMHLC_02874 1.5e-42 S COG NOG38524 non supervised orthologous group
MKDMMHLC_02877 7.9e-60 mleR K LysR substrate binding domain
MKDMMHLC_02878 5.4e-132 K LysR family
MKDMMHLC_02879 2.4e-301 1.3.5.4 C FMN_bind
MKDMMHLC_02880 2.8e-239 P Sodium:sulfate symporter transmembrane region
MKDMMHLC_02881 1.2e-82 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
MKDMMHLC_02882 9.2e-28 padC Q Phenolic acid decarboxylase
MKDMMHLC_02883 2.2e-99 padR K Virulence activator alpha C-term
MKDMMHLC_02884 2.7e-79 T Universal stress protein family
MKDMMHLC_02885 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MKDMMHLC_02887 3.5e-130 L MobA MobL family protein
MKDMMHLC_02888 1.3e-117
MKDMMHLC_02889 1.5e-65
MKDMMHLC_02890 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
MKDMMHLC_02891 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
MKDMMHLC_02892 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
MKDMMHLC_02893 2.3e-107 L Integrase
MKDMMHLC_02894 4.9e-16
MKDMMHLC_02895 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MKDMMHLC_02896 9.1e-186 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MKDMMHLC_02897 0.0 rafA 3.2.1.22 G alpha-galactosidase
MKDMMHLC_02898 1.5e-65 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MKDMMHLC_02899 4.5e-238 asdA 4.1.1.12 E Aminotransferase class I and II
MKDMMHLC_02900 1.2e-198 aspT U Predicted Permease Membrane Region
MKDMMHLC_02901 3.4e-56 L Transposase IS66 family
MKDMMHLC_02902 1.5e-194 pbuX F xanthine permease
MKDMMHLC_02903 3.7e-24
MKDMMHLC_02904 1.9e-56 XK27_01125 L PFAM IS66 Orf2 family protein
MKDMMHLC_02905 8e-18
MKDMMHLC_02906 4.2e-113 papP P ABC transporter, permease protein
MKDMMHLC_02907 4.3e-113 P ABC transporter permease
MKDMMHLC_02908 4.3e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MKDMMHLC_02909 9.1e-153 cjaA ET ABC transporter substrate-binding protein
MKDMMHLC_02910 1.7e-18
MKDMMHLC_02911 2e-184 L Psort location Cytoplasmic, score
MKDMMHLC_02912 8e-68 C lyase activity
MKDMMHLC_02913 4.8e-94 K Bacterial regulatory proteins, tetR family
MKDMMHLC_02914 1.2e-191 1.1.1.219 GM Male sterility protein
MKDMMHLC_02915 1.6e-100 S Protein of unknown function (DUF1211)
MKDMMHLC_02916 2.1e-11
MKDMMHLC_02917 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
MKDMMHLC_02919 2.9e-125 S Phage Mu protein F like protein
MKDMMHLC_02920 1.2e-12 ytgB S Transglycosylase associated protein
MKDMMHLC_02921 6.6e-136 L Replication protein
MKDMMHLC_02922 1.5e-15 S Alpha/beta hydrolase of unknown function (DUF915)
MKDMMHLC_02923 4.7e-28 celB 2.7.1.207 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MKDMMHLC_02924 7.9e-26
MKDMMHLC_02925 1.2e-40
MKDMMHLC_02926 5.7e-86
MKDMMHLC_02927 1.1e-43 relB L Addiction module antitoxin, RelB DinJ family
MKDMMHLC_02928 5.1e-209 mccF V LD-carboxypeptidase
MKDMMHLC_02929 1.4e-78 K Acetyltransferase (GNAT) domain
MKDMMHLC_02930 4.2e-150 S Uncharacterised protein, DegV family COG1307
MKDMMHLC_02931 1.8e-85 2.5.1.74 H UbiA prenyltransferase family
MKDMMHLC_02932 3.7e-31 tnp2PF3 L manually curated
MKDMMHLC_02933 1.2e-163 L PFAM Integrase catalytic region
MKDMMHLC_02934 1.7e-88 L Helix-turn-helix domain
MKDMMHLC_02935 7e-57
MKDMMHLC_02936 6e-31 cspA K Cold shock protein
MKDMMHLC_02937 3.8e-40
MKDMMHLC_02938 2.7e-31 L Transposase
MKDMMHLC_02940 3.1e-36 L Resolvase, N terminal domain
MKDMMHLC_02941 3e-25
MKDMMHLC_02942 6.2e-32
MKDMMHLC_02943 9e-14 Q Methyltransferase
MKDMMHLC_02944 4.8e-58
MKDMMHLC_02945 4.2e-70 S Pyrimidine dimer DNA glycosylase
MKDMMHLC_02946 1.3e-23 hol S Bacteriophage holin
MKDMMHLC_02947 3e-116 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MKDMMHLC_02950 3.1e-56 tnp2PF3 L Transposase DDE domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)