ORF_ID e_value Gene_name EC_number CAZy COGs Description
IEMGHHED_00001 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IEMGHHED_00002 9.5e-31
IEMGHHED_00003 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
IEMGHHED_00004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
IEMGHHED_00005 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IEMGHHED_00006 1.2e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEMGHHED_00007 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
IEMGHHED_00008 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
IEMGHHED_00009 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IEMGHHED_00010 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
IEMGHHED_00011 2.6e-35 yaaA S S4 domain protein YaaA
IEMGHHED_00012 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IEMGHHED_00013 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEMGHHED_00014 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IEMGHHED_00015 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
IEMGHHED_00016 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
IEMGHHED_00017 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IEMGHHED_00018 2.8e-14 L PFAM transposase, IS4 family protein
IEMGHHED_00019 9.3e-86
IEMGHHED_00020 6.7e-281 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEMGHHED_00021 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
IEMGHHED_00022 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEMGHHED_00023 4.4e-140 ypuA S Protein of unknown function (DUF1002)
IEMGHHED_00024 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
IEMGHHED_00025 7.3e-126 S Alpha/beta hydrolase family
IEMGHHED_00026 1.1e-59 L An automated process has identified a potential problem with this gene model
IEMGHHED_00027 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
IEMGHHED_00028 9e-98
IEMGHHED_00029 4.9e-108 K LysR substrate binding domain
IEMGHHED_00030 1e-20
IEMGHHED_00031 2.3e-215 S Sterol carrier protein domain
IEMGHHED_00032 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
IEMGHHED_00033 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
IEMGHHED_00034 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IEMGHHED_00035 5.7e-233 arcA 3.5.3.6 E Arginine
IEMGHHED_00036 9e-137 lysR5 K LysR substrate binding domain
IEMGHHED_00037 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
IEMGHHED_00038 1e-48 S Metal binding domain of Ada
IEMGHHED_00039 2.3e-43 ybhL S Belongs to the BI1 family
IEMGHHED_00041 1.2e-210 S Bacterial protein of unknown function (DUF871)
IEMGHHED_00042 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IEMGHHED_00043 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
IEMGHHED_00044 1.5e-102 srtA 3.4.22.70 M sortase family
IEMGHHED_00045 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEMGHHED_00046 5.9e-24
IEMGHHED_00047 2.1e-173 M Glycosyl hydrolases family 25
IEMGHHED_00048 5e-29
IEMGHHED_00049 7.9e-19
IEMGHHED_00051 1.1e-07
IEMGHHED_00052 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
IEMGHHED_00053 7.1e-38
IEMGHHED_00059 1.6e-36
IEMGHHED_00060 1.1e-08
IEMGHHED_00061 6.5e-125 Z012_12235 S Baseplate J-like protein
IEMGHHED_00062 9.5e-33
IEMGHHED_00063 1.2e-48
IEMGHHED_00064 5.7e-104
IEMGHHED_00065 2.1e-46
IEMGHHED_00066 1.2e-58 M LysM domain
IEMGHHED_00067 0.0 3.4.14.13 M Phage tail tape measure protein TP901
IEMGHHED_00069 9e-27
IEMGHHED_00070 4e-56
IEMGHHED_00071 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
IEMGHHED_00072 4.7e-57
IEMGHHED_00073 1.7e-45
IEMGHHED_00074 2.6e-75
IEMGHHED_00075 2.3e-29 S Protein of unknown function (DUF4054)
IEMGHHED_00076 4.6e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
IEMGHHED_00077 1.1e-59
IEMGHHED_00078 2e-83 S Uncharacterized protein conserved in bacteria (DUF2213)
IEMGHHED_00079 9.8e-16 S Lysin motif
IEMGHHED_00080 2.2e-26 S HNH endonuclease
IEMGHHED_00082 9.5e-96 S Phage Mu protein F like protein
IEMGHHED_00083 7e-142 S Protein of unknown function (DUF1073)
IEMGHHED_00084 1.8e-230 S Terminase-like family
IEMGHHED_00085 1.5e-28 L Terminase small subunit
IEMGHHED_00086 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
IEMGHHED_00087 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
IEMGHHED_00095 2.1e-14
IEMGHHED_00096 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
IEMGHHED_00102 1.4e-51 dnaC L IstB-like ATP binding protein
IEMGHHED_00103 2.3e-33 S Conserved phage C-terminus (Phg_2220_C)
IEMGHHED_00104 2.4e-59 S Protein of unknown function (DUF1071)
IEMGHHED_00108 5e-07 K Helix-turn-helix XRE-family like proteins
IEMGHHED_00109 7.2e-10
IEMGHHED_00114 3.5e-92 S AntA/AntB antirepressor
IEMGHHED_00115 4.3e-15
IEMGHHED_00117 1.4e-12
IEMGHHED_00118 1.1e-13 ansR 3.4.21.88 K Cro/C1-type HTH DNA-binding domain
IEMGHHED_00119 5.7e-18 S Pfam:Peptidase_M78
IEMGHHED_00124 1.6e-20 S YjcQ protein
IEMGHHED_00125 4.2e-180 sip L Belongs to the 'phage' integrase family
IEMGHHED_00126 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
IEMGHHED_00127 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
IEMGHHED_00128 0.0 dnaK O Heat shock 70 kDa protein
IEMGHHED_00129 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IEMGHHED_00130 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
IEMGHHED_00131 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
IEMGHHED_00132 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IEMGHHED_00133 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IEMGHHED_00134 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IEMGHHED_00135 3.2e-47 rplGA J ribosomal protein
IEMGHHED_00136 8.8e-47 ylxR K Protein of unknown function (DUF448)
IEMGHHED_00137 1.4e-196 nusA K Participates in both transcription termination and antitermination
IEMGHHED_00138 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
IEMGHHED_00139 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEMGHHED_00140 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
IEMGHHED_00141 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
IEMGHHED_00142 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
IEMGHHED_00143 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IEMGHHED_00144 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
IEMGHHED_00145 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
IEMGHHED_00146 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IEMGHHED_00147 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
IEMGHHED_00148 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
IEMGHHED_00149 2.9e-116 plsC 2.3.1.51 I Acyltransferase
IEMGHHED_00150 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
IEMGHHED_00151 0.0 pepO 3.4.24.71 O Peptidase family M13
IEMGHHED_00152 0.0 mdlB V ABC transporter
IEMGHHED_00153 0.0 mdlA V ABC transporter
IEMGHHED_00154 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
IEMGHHED_00155 3e-38 ynzC S UPF0291 protein
IEMGHHED_00156 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IEMGHHED_00157 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
IEMGHHED_00158 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
IEMGHHED_00159 4.6e-213 S SLAP domain
IEMGHHED_00160 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
IEMGHHED_00161 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
IEMGHHED_00162 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IEMGHHED_00163 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
IEMGHHED_00164 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IEMGHHED_00165 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IEMGHHED_00166 2.7e-258 yfnA E amino acid
IEMGHHED_00167 0.0 V FtsX-like permease family
IEMGHHED_00168 4.1e-133 cysA V ABC transporter, ATP-binding protein
IEMGHHED_00169 3.4e-23
IEMGHHED_00171 2.5e-288 pipD E Dipeptidase
IEMGHHED_00172 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
IEMGHHED_00173 0.0 smc D Required for chromosome condensation and partitioning
IEMGHHED_00174 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
IEMGHHED_00175 2.1e-308 oppA E ABC transporter substrate-binding protein
IEMGHHED_00176 3.1e-240 oppA E ABC transporter substrate-binding protein
IEMGHHED_00177 9.7e-46 oppA E ABC transporter substrate-binding protein
IEMGHHED_00178 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
IEMGHHED_00179 2.6e-172 oppB P ABC transporter permease
IEMGHHED_00180 1.5e-170 oppF P Belongs to the ABC transporter superfamily
IEMGHHED_00181 1.1e-192 oppD P Belongs to the ABC transporter superfamily
IEMGHHED_00182 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEMGHHED_00183 3.2e-181 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
IEMGHHED_00184 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IEMGHHED_00185 7.6e-305 yloV S DAK2 domain fusion protein YloV
IEMGHHED_00186 4e-57 asp S Asp23 family, cell envelope-related function
IEMGHHED_00187 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
IEMGHHED_00188 1.4e-30
IEMGHHED_00189 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
IEMGHHED_00190 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
IEMGHHED_00191 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
IEMGHHED_00192 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
IEMGHHED_00193 1.1e-138 stp 3.1.3.16 T phosphatase
IEMGHHED_00194 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IEMGHHED_00195 1.6e-171 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IEMGHHED_00196 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IEMGHHED_00197 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
IEMGHHED_00198 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
IEMGHHED_00199 1.1e-77 6.3.3.2 S ASCH
IEMGHHED_00200 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
IEMGHHED_00201 4.7e-151 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
IEMGHHED_00202 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEMGHHED_00203 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEMGHHED_00204 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
IEMGHHED_00205 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IEMGHHED_00206 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IEMGHHED_00207 3.4e-71 yqhY S Asp23 family, cell envelope-related function
IEMGHHED_00208 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEMGHHED_00209 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IEMGHHED_00210 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
IEMGHHED_00211 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
IEMGHHED_00212 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEMGHHED_00213 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
IEMGHHED_00215 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
IEMGHHED_00216 4.3e-298 S Predicted membrane protein (DUF2207)
IEMGHHED_00217 1.2e-155 cinI S Serine hydrolase (FSH1)
IEMGHHED_00218 1e-205 M Glycosyl hydrolases family 25
IEMGHHED_00220 8.5e-178 I Carboxylesterase family
IEMGHHED_00221 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
IEMGHHED_00222 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_00223 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_00224 1.7e-148 S haloacid dehalogenase-like hydrolase
IEMGHHED_00225 7e-50
IEMGHHED_00226 1.9e-37
IEMGHHED_00227 1.2e-63 S Alpha beta hydrolase
IEMGHHED_00228 1e-23 S Alpha beta hydrolase
IEMGHHED_00229 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
IEMGHHED_00230 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
IEMGHHED_00231 7.1e-46
IEMGHHED_00232 3.1e-148 glcU U sugar transport
IEMGHHED_00233 3.7e-250 lctP C L-lactate permease
IEMGHHED_00234 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
IEMGHHED_00235 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEMGHHED_00236 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
IEMGHHED_00237 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
IEMGHHED_00238 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEMGHHED_00239 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
IEMGHHED_00240 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
IEMGHHED_00241 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IEMGHHED_00242 1.5e-102 GM NmrA-like family
IEMGHHED_00243 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00244 2e-57 clcA P chloride
IEMGHHED_00245 3.9e-113 L PFAM Integrase catalytic
IEMGHHED_00246 4.3e-283 lsa S ABC transporter
IEMGHHED_00247 2.4e-44
IEMGHHED_00248 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
IEMGHHED_00249 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
IEMGHHED_00250 9.7e-52 S Iron-sulfur cluster assembly protein
IEMGHHED_00251 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IEMGHHED_00252 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
IEMGHHED_00253 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
IEMGHHED_00254 4.7e-38
IEMGHHED_00255 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEMGHHED_00256 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
IEMGHHED_00257 2.8e-135
IEMGHHED_00258 1.3e-258 glnPH2 P ABC transporter permease
IEMGHHED_00259 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEMGHHED_00260 6.4e-224 S Cysteine-rich secretory protein family
IEMGHHED_00261 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
IEMGHHED_00262 1.4e-112
IEMGHHED_00263 6.3e-202 yibE S overlaps another CDS with the same product name
IEMGHHED_00264 4.9e-129 yibF S overlaps another CDS with the same product name
IEMGHHED_00265 2.5e-144 I alpha/beta hydrolase fold
IEMGHHED_00266 0.0 G Belongs to the glycosyl hydrolase 31 family
IEMGHHED_00267 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEMGHHED_00268 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEMGHHED_00269 3.3e-275 yjeM E Amino Acid
IEMGHHED_00270 5.8e-83 S Fic/DOC family
IEMGHHED_00271 2.7e-285
IEMGHHED_00272 3.2e-77
IEMGHHED_00273 2.3e-87 S Protein of unknown function (DUF805)
IEMGHHED_00274 5.6e-68 O OsmC-like protein
IEMGHHED_00275 2.1e-208 EGP Major facilitator Superfamily
IEMGHHED_00276 2.5e-215 sptS 2.7.13.3 T Histidine kinase
IEMGHHED_00277 6.4e-24 K response regulator
IEMGHHED_00278 2.4e-70 scrR K Periplasmic binding protein domain
IEMGHHED_00279 5.5e-36
IEMGHHED_00280 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
IEMGHHED_00281 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
IEMGHHED_00282 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IEMGHHED_00283 0.0 lacZ 3.2.1.23 G -beta-galactosidase
IEMGHHED_00284 0.0 lacS G Transporter
IEMGHHED_00285 3.2e-165 lacR K Transcriptional regulator
IEMGHHED_00286 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
IEMGHHED_00287 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
IEMGHHED_00288 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
IEMGHHED_00289 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
IEMGHHED_00290 2e-106 K Transcriptional regulator, AbiEi antitoxin
IEMGHHED_00291 1.2e-188 K Periplasmic binding protein-like domain
IEMGHHED_00292 5.8e-73 S domain protein
IEMGHHED_00294 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
IEMGHHED_00295 3e-145 potD2 P ABC transporter
IEMGHHED_00296 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IEMGHHED_00297 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
IEMGHHED_00298 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEMGHHED_00299 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
IEMGHHED_00300 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
IEMGHHED_00301 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IEMGHHED_00302 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
IEMGHHED_00303 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IEMGHHED_00304 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
IEMGHHED_00305 2.3e-56 G Xylose isomerase domain protein TIM barrel
IEMGHHED_00306 8.4e-90 nanK GK ROK family
IEMGHHED_00307 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
IEMGHHED_00308 3.7e-66 K Helix-turn-helix domain, rpiR family
IEMGHHED_00309 7.1e-263 E ABC transporter, substratebinding protein
IEMGHHED_00310 9.1e-10 K peptidyl-tyrosine sulfation
IEMGHHED_00312 4.5e-131 S interspecies interaction between organisms
IEMGHHED_00313 2.7e-34
IEMGHHED_00316 1.9e-21
IEMGHHED_00317 6e-148
IEMGHHED_00318 6.7e-170
IEMGHHED_00319 2e-263 glnA 6.3.1.2 E glutamine synthetase
IEMGHHED_00320 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
IEMGHHED_00321 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IEMGHHED_00322 1.5e-65 yqhL P Rhodanese-like protein
IEMGHHED_00323 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
IEMGHHED_00324 4e-119 gluP 3.4.21.105 S Rhomboid family
IEMGHHED_00325 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IEMGHHED_00326 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
IEMGHHED_00327 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
IEMGHHED_00328 0.0 S membrane
IEMGHHED_00329 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
IEMGHHED_00330 1.3e-38 S RelB antitoxin
IEMGHHED_00331 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IEMGHHED_00332 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEMGHHED_00333 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
IEMGHHED_00334 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IEMGHHED_00335 8.7e-159 isdE P Periplasmic binding protein
IEMGHHED_00336 6.3e-123 M Iron Transport-associated domain
IEMGHHED_00337 3e-09 isdH M Iron Transport-associated domain
IEMGHHED_00338 2.2e-89
IEMGHHED_00339 2.2e-113 S SLAP domain
IEMGHHED_00340 2.9e-53 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IEMGHHED_00341 5.7e-46 S An automated process has identified a potential problem with this gene model
IEMGHHED_00342 3e-137 S Protein of unknown function (DUF3100)
IEMGHHED_00343 4e-245 3.5.1.47 S Peptidase dimerisation domain
IEMGHHED_00344 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
IEMGHHED_00345 0.0 oppA E ABC transporter
IEMGHHED_00346 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
IEMGHHED_00347 0.0 mco Q Multicopper oxidase
IEMGHHED_00348 1.9e-25
IEMGHHED_00349 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
IEMGHHED_00350 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
IEMGHHED_00351 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEMGHHED_00352 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEMGHHED_00353 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IEMGHHED_00354 8.1e-91 cjaA ET ABC transporter substrate-binding protein
IEMGHHED_00355 3e-53 cjaA ET ABC transporter substrate-binding protein
IEMGHHED_00356 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEMGHHED_00357 2e-110 P ABC transporter permease
IEMGHHED_00358 1.1e-108 papP P ABC transporter, permease protein
IEMGHHED_00360 8.8e-62 yodB K Transcriptional regulator, HxlR family
IEMGHHED_00361 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEMGHHED_00362 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
IEMGHHED_00363 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
IEMGHHED_00364 1.5e-72 S Aminoacyl-tRNA editing domain
IEMGHHED_00365 1.2e-54 S Abi-like protein
IEMGHHED_00366 8e-224 S SLAP domain
IEMGHHED_00367 3.9e-128 S CAAX protease self-immunity
IEMGHHED_00368 1.3e-277 arlS 2.7.13.3 T Histidine kinase
IEMGHHED_00369 1.2e-126 K response regulator
IEMGHHED_00370 4.7e-97 yceD S Uncharacterized ACR, COG1399
IEMGHHED_00371 1.7e-215 ylbM S Belongs to the UPF0348 family
IEMGHHED_00372 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
IEMGHHED_00373 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
IEMGHHED_00374 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IEMGHHED_00375 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
IEMGHHED_00376 4.2e-84 yqeG S HAD phosphatase, family IIIA
IEMGHHED_00377 9.2e-201 tnpB L Putative transposase DNA-binding domain
IEMGHHED_00378 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IEMGHHED_00379 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IEMGHHED_00380 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
IEMGHHED_00381 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IEMGHHED_00382 4e-98 rihB 3.2.2.1 F Nucleoside
IEMGHHED_00383 3.9e-23 S domain protein
IEMGHHED_00384 1.7e-168 V ABC transporter
IEMGHHED_00385 7.7e-39 S Protein of unknown function (DUF3021)
IEMGHHED_00386 4.2e-53 K LytTr DNA-binding domain
IEMGHHED_00389 3e-107 L Transposase
IEMGHHED_00390 4.3e-75
IEMGHHED_00391 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IEMGHHED_00392 1.3e-168 dnaI L Primosomal protein DnaI
IEMGHHED_00393 5.1e-251 dnaB L Replication initiation and membrane attachment
IEMGHHED_00394 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IEMGHHED_00395 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IEMGHHED_00396 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
IEMGHHED_00397 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IEMGHHED_00398 3.5e-25 qmcA O prohibitin homologues
IEMGHHED_00399 7.4e-105 qmcA O prohibitin homologues
IEMGHHED_00400 8e-51 L RelB antitoxin
IEMGHHED_00401 4.5e-188 S Bacteriocin helveticin-J
IEMGHHED_00402 4.4e-283 M Peptidase family M1 domain
IEMGHHED_00403 1.8e-176 S SLAP domain
IEMGHHED_00404 6.9e-218 mepA V MATE efflux family protein
IEMGHHED_00405 2.2e-246 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
IEMGHHED_00406 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
IEMGHHED_00407 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
IEMGHHED_00409 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
IEMGHHED_00410 6.5e-221 ecsB U ABC transporter
IEMGHHED_00411 5.7e-135 ecsA V ABC transporter, ATP-binding protein
IEMGHHED_00412 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
IEMGHHED_00413 3.9e-25
IEMGHHED_00414 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
IEMGHHED_00415 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
IEMGHHED_00416 1.1e-265
IEMGHHED_00417 2.2e-42 S Domain of unknown function DUF1829
IEMGHHED_00418 3.7e-27 L Transposase
IEMGHHED_00419 5.4e-13
IEMGHHED_00420 1.6e-85 L Transposase
IEMGHHED_00421 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEMGHHED_00422 0.0 L AAA domain
IEMGHHED_00423 1e-226 yhaO L Ser Thr phosphatase family protein
IEMGHHED_00424 7.2e-56 yheA S Belongs to the UPF0342 family
IEMGHHED_00425 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
IEMGHHED_00426 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEMGHHED_00427 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
IEMGHHED_00428 3.7e-27 L Transposase
IEMGHHED_00429 7.5e-103 G Phosphoglycerate mutase family
IEMGHHED_00430 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
IEMGHHED_00432 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
IEMGHHED_00433 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
IEMGHHED_00434 5.6e-179 S PFAM Archaeal ATPase
IEMGHHED_00435 2.4e-73 S cog cog1373
IEMGHHED_00436 3.7e-27 L Transposase
IEMGHHED_00437 2.4e-128 S cog cog1373
IEMGHHED_00438 1.4e-109 yniG EGP Major facilitator Superfamily
IEMGHHED_00439 5.4e-237 L transposase, IS605 OrfB family
IEMGHHED_00440 4.5e-76 yniG EGP Major facilitator Superfamily
IEMGHHED_00441 4.9e-35
IEMGHHED_00443 1.3e-42
IEMGHHED_00444 1.9e-75 M LysM domain
IEMGHHED_00445 1e-20 S Enterocin A Immunity
IEMGHHED_00447 5.7e-43 2.4.1.33 V HlyD family secretion protein
IEMGHHED_00448 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IEMGHHED_00449 2.9e-79 K LytTr DNA-binding domain
IEMGHHED_00450 2.1e-78 2.7.13.3 T GHKL domain
IEMGHHED_00452 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
IEMGHHED_00453 7.7e-26
IEMGHHED_00454 5.7e-84 S PFAM Archaeal ATPase
IEMGHHED_00455 2.2e-85 S PFAM Archaeal ATPase
IEMGHHED_00456 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
IEMGHHED_00457 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
IEMGHHED_00458 6.7e-98 M ErfK YbiS YcfS YnhG
IEMGHHED_00459 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IEMGHHED_00460 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
IEMGHHED_00462 4.7e-46 pspC KT PspC domain
IEMGHHED_00463 3.3e-237 L COG2963 Transposase and inactivated derivatives
IEMGHHED_00464 1.1e-282 phoR 2.7.13.3 T Histidine kinase
IEMGHHED_00465 9.5e-121 T Transcriptional regulatory protein, C terminal
IEMGHHED_00466 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
IEMGHHED_00467 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEMGHHED_00468 1.2e-152 pstA P Phosphate transport system permease protein PstA
IEMGHHED_00469 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
IEMGHHED_00470 4.2e-145 pstS P Phosphate
IEMGHHED_00471 1.3e-30
IEMGHHED_00472 6.3e-192 oppA E ABC transporter, substratebinding protein
IEMGHHED_00473 4.7e-275 ytgP S Polysaccharide biosynthesis protein
IEMGHHED_00474 5.2e-08
IEMGHHED_00475 3e-89 ntd 2.4.2.6 F Nucleoside
IEMGHHED_00476 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEMGHHED_00477 3.7e-148 ptp3 3.1.3.48 T Tyrosine phosphatase family
IEMGHHED_00478 2.2e-82 uspA T universal stress protein
IEMGHHED_00480 3.9e-15 phnD P Phosphonate ABC transporter
IEMGHHED_00481 3.1e-133 phnD P Phosphonate ABC transporter
IEMGHHED_00482 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IEMGHHED_00483 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IEMGHHED_00484 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
IEMGHHED_00485 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
IEMGHHED_00486 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEMGHHED_00487 1.1e-121 3.6.1.27 I Acid phosphatase homologues
IEMGHHED_00488 2.8e-168 K LysR substrate binding domain
IEMGHHED_00489 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IEMGHHED_00490 6.2e-43 1.3.5.4 C FAD binding domain
IEMGHHED_00491 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
IEMGHHED_00492 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
IEMGHHED_00493 1.8e-31 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEMGHHED_00494 1.3e-131 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
IEMGHHED_00495 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
IEMGHHED_00496 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
IEMGHHED_00497 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
IEMGHHED_00498 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
IEMGHHED_00499 6.4e-243 cydA 1.10.3.14 C ubiquinol oxidase
IEMGHHED_00500 7e-23 cydA 1.10.3.14 C ubiquinol oxidase
IEMGHHED_00501 3.7e-130 ybbH_2 K rpiR family
IEMGHHED_00502 3.4e-195 S Bacterial protein of unknown function (DUF871)
IEMGHHED_00503 1.2e-213 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEMGHHED_00504 1.8e-119 S Putative esterase
IEMGHHED_00505 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IEMGHHED_00506 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
IEMGHHED_00507 8.5e-260 qacA EGP Major facilitator Superfamily
IEMGHHED_00508 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IEMGHHED_00511 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
IEMGHHED_00514 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
IEMGHHED_00515 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
IEMGHHED_00516 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
IEMGHHED_00517 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
IEMGHHED_00518 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IEMGHHED_00519 7.5e-100 J Acetyltransferase (GNAT) domain
IEMGHHED_00520 1.4e-110 yjbF S SNARE associated Golgi protein
IEMGHHED_00521 6e-151 I alpha/beta hydrolase fold
IEMGHHED_00522 1.2e-62 hipB K Helix-turn-helix
IEMGHHED_00523 6e-85 hipB K Helix-turn-helix
IEMGHHED_00524 1.4e-15 S cog cog1373
IEMGHHED_00525 1e-30 S cog cog1373
IEMGHHED_00526 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
IEMGHHED_00527 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
IEMGHHED_00528 6.1e-227 L COG3547 Transposase and inactivated derivatives
IEMGHHED_00529 1.8e-163
IEMGHHED_00530 7.8e-26 K Acetyltransferase (GNAT) domain
IEMGHHED_00532 0.0 ydgH S MMPL family
IEMGHHED_00533 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
IEMGHHED_00534 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
IEMGHHED_00535 1.8e-154 corA P CorA-like Mg2+ transporter protein
IEMGHHED_00536 6.7e-240 G Bacterial extracellular solute-binding protein
IEMGHHED_00537 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
IEMGHHED_00538 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
IEMGHHED_00539 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
IEMGHHED_00540 1.9e-203 malK P ATPases associated with a variety of cellular activities
IEMGHHED_00541 1.3e-281 pipD E Dipeptidase
IEMGHHED_00542 1.9e-158 endA F DNA RNA non-specific endonuclease
IEMGHHED_00543 8e-182 dnaQ 2.7.7.7 L EXOIII
IEMGHHED_00544 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IEMGHHED_00545 3e-116 yviA S Protein of unknown function (DUF421)
IEMGHHED_00546 1.1e-56 S Protein of unknown function (DUF3290)
IEMGHHED_00548 3.8e-139 pnuC H nicotinamide mononucleotide transporter
IEMGHHED_00549 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
IEMGHHED_00550 1.6e-105 tag 3.2.2.20 L glycosylase
IEMGHHED_00551 3.9e-84
IEMGHHED_00552 1.7e-273 S Calcineurin-like phosphoesterase
IEMGHHED_00553 0.0 asnB 6.3.5.4 E Asparagine synthase
IEMGHHED_00554 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
IEMGHHED_00555 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
IEMGHHED_00556 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IEMGHHED_00557 2.1e-103 S Iron-sulfur cluster assembly protein
IEMGHHED_00558 1.5e-230 XK27_04775 S PAS domain
IEMGHHED_00559 1e-210 yttB EGP Major facilitator Superfamily
IEMGHHED_00560 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00561 4e-08
IEMGHHED_00562 6.6e-56
IEMGHHED_00563 2.7e-57
IEMGHHED_00564 1.6e-11
IEMGHHED_00565 8.1e-126 S PAS domain
IEMGHHED_00566 2.9e-277 V ABC transporter transmembrane region
IEMGHHED_00567 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
IEMGHHED_00568 3.1e-130 T Transcriptional regulatory protein, C terminal
IEMGHHED_00569 5.2e-187 T GHKL domain
IEMGHHED_00570 3.4e-76 S Peptidase propeptide and YPEB domain
IEMGHHED_00571 2.5e-72 S Peptidase propeptide and YPEB domain
IEMGHHED_00572 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IEMGHHED_00573 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
IEMGHHED_00574 7e-68 V ABC transporter transmembrane region
IEMGHHED_00575 9e-161 V ABC transporter transmembrane region
IEMGHHED_00576 2.3e-309 oppA3 E ABC transporter, substratebinding protein
IEMGHHED_00577 2.4e-60 ypaA S Protein of unknown function (DUF1304)
IEMGHHED_00578 2.1e-28 S Peptidase propeptide and YPEB domain
IEMGHHED_00579 7.1e-237 L transposase, IS605 OrfB family
IEMGHHED_00580 8.8e-58 S Peptidase propeptide and YPEB domain
IEMGHHED_00581 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IEMGHHED_00582 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
IEMGHHED_00583 7.1e-98 E GDSL-like Lipase/Acylhydrolase
IEMGHHED_00584 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
IEMGHHED_00585 1.6e-143 aatB ET ABC transporter substrate-binding protein
IEMGHHED_00586 1e-105 glnQ 3.6.3.21 E ABC transporter
IEMGHHED_00587 1.5e-107 glnP P ABC transporter permease
IEMGHHED_00588 0.0 helD 3.6.4.12 L DNA helicase
IEMGHHED_00589 2.7e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
IEMGHHED_00590 1.4e-126 pgm3 G Phosphoglycerate mutase family
IEMGHHED_00591 3.7e-27 L Transposase
IEMGHHED_00592 1.2e-241 S response to antibiotic
IEMGHHED_00593 4.9e-125
IEMGHHED_00594 0.0 3.6.3.8 P P-type ATPase
IEMGHHED_00595 8.7e-66 2.7.1.191 G PTS system fructose IIA component
IEMGHHED_00596 4.4e-43
IEMGHHED_00597 5.9e-09
IEMGHHED_00598 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
IEMGHHED_00599 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
IEMGHHED_00600 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
IEMGHHED_00601 3.7e-27 L Transposase
IEMGHHED_00602 5.2e-104
IEMGHHED_00605 1.9e-117 cps1D M Domain of unknown function (DUF4422)
IEMGHHED_00606 6.7e-110 rfbP M Bacterial sugar transferase
IEMGHHED_00607 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
IEMGHHED_00608 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
IEMGHHED_00609 6.5e-146 epsB M biosynthesis protein
IEMGHHED_00610 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEMGHHED_00613 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IEMGHHED_00614 3.5e-175 S Cysteine-rich secretory protein family
IEMGHHED_00615 1.6e-41
IEMGHHED_00616 2.6e-118 M NlpC/P60 family
IEMGHHED_00617 1.4e-136 M NlpC P60 family protein
IEMGHHED_00618 5e-88 M NlpC/P60 family
IEMGHHED_00619 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
IEMGHHED_00620 3.9e-42
IEMGHHED_00621 1.7e-279 S O-antigen ligase like membrane protein
IEMGHHED_00622 3.3e-112
IEMGHHED_00623 4.7e-221 tnpB L Putative transposase DNA-binding domain
IEMGHHED_00624 5.5e-77 nrdI F NrdI Flavodoxin like
IEMGHHED_00625 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEMGHHED_00626 2.5e-68
IEMGHHED_00627 9.1e-112 yvpB S Peptidase_C39 like family
IEMGHHED_00628 1.1e-83 S Threonine/Serine exporter, ThrE
IEMGHHED_00629 2.4e-136 thrE S Putative threonine/serine exporter
IEMGHHED_00630 8.9e-292 S ABC transporter
IEMGHHED_00631 8.3e-58
IEMGHHED_00632 5e-72 rimL J Acetyltransferase (GNAT) domain
IEMGHHED_00633 1.4e-34
IEMGHHED_00634 1.2e-30
IEMGHHED_00635 1.8e-111 S Protein of unknown function (DUF554)
IEMGHHED_00636 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEMGHHED_00637 0.0 pepF E oligoendopeptidase F
IEMGHHED_00638 2.9e-31
IEMGHHED_00639 1.3e-69 doc S Prophage maintenance system killer protein
IEMGHHED_00642 4.6e-27 S Enterocin A Immunity
IEMGHHED_00643 1.7e-22 blpT
IEMGHHED_00644 0.0 pepO 3.4.24.71 O Peptidase family M13
IEMGHHED_00646 1.6e-25 K Helix-turn-helix XRE-family like proteins
IEMGHHED_00647 1.2e-11
IEMGHHED_00648 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
IEMGHHED_00649 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
IEMGHHED_00650 2e-264 lctP C L-lactate permease
IEMGHHED_00651 5e-129 znuB U ABC 3 transport family
IEMGHHED_00652 1.6e-117 fhuC P ABC transporter
IEMGHHED_00653 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
IEMGHHED_00654 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
IEMGHHED_00655 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
IEMGHHED_00656 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
IEMGHHED_00657 1.8e-136 fruR K DeoR C terminal sensor domain
IEMGHHED_00658 1.8e-218 natB CP ABC-2 family transporter protein
IEMGHHED_00659 1.1e-164 natA S ABC transporter, ATP-binding protein
IEMGHHED_00660 1.7e-67
IEMGHHED_00661 2e-23
IEMGHHED_00662 8.2e-31 yozG K Transcriptional regulator
IEMGHHED_00663 3.7e-83
IEMGHHED_00664 3e-21
IEMGHHED_00667 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00668 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IEMGHHED_00669 1.2e-127 K LytTr DNA-binding domain
IEMGHHED_00670 1.6e-132 2.7.13.3 T GHKL domain
IEMGHHED_00671 3.7e-27 L Transposase
IEMGHHED_00672 1.2e-16
IEMGHHED_00673 2.1e-255 S Archaea bacterial proteins of unknown function
IEMGHHED_00674 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
IEMGHHED_00675 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
IEMGHHED_00676 1e-24
IEMGHHED_00677 9.5e-26
IEMGHHED_00678 2.5e-33
IEMGHHED_00679 1.4e-53 S Enterocin A Immunity
IEMGHHED_00680 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
IEMGHHED_00681 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IEMGHHED_00682 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
IEMGHHED_00683 9.6e-121 K response regulator
IEMGHHED_00685 0.0 V ABC transporter
IEMGHHED_00686 4.2e-144 V ABC transporter, ATP-binding protein
IEMGHHED_00687 1.2e-145 V ABC transporter, ATP-binding protein
IEMGHHED_00688 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
IEMGHHED_00689 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
IEMGHHED_00690 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
IEMGHHED_00691 8.5e-154 spo0J K Belongs to the ParB family
IEMGHHED_00692 3.4e-138 soj D Sporulation initiation inhibitor
IEMGHHED_00693 1.5e-147 noc K Belongs to the ParB family
IEMGHHED_00694 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
IEMGHHED_00695 3e-53 cvpA S Colicin V production protein
IEMGHHED_00697 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
IEMGHHED_00698 6e-151 3.1.3.48 T Tyrosine phosphatase family
IEMGHHED_00699 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
IEMGHHED_00700 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
IEMGHHED_00701 2.4e-110 K WHG domain
IEMGHHED_00702 3e-37
IEMGHHED_00703 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00704 1.3e-273 pipD E Dipeptidase
IEMGHHED_00705 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
IEMGHHED_00706 3.3e-176 hrtB V ABC transporter permease
IEMGHHED_00707 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
IEMGHHED_00708 3.5e-111 G phosphoglycerate mutase
IEMGHHED_00709 4.1e-141 aroD S Alpha/beta hydrolase family
IEMGHHED_00710 2.2e-142 S Belongs to the UPF0246 family
IEMGHHED_00711 9e-121
IEMGHHED_00712 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
IEMGHHED_00713 3.9e-186 S Putative peptidoglycan binding domain
IEMGHHED_00714 4e-16
IEMGHHED_00715 2.1e-92 liaI S membrane
IEMGHHED_00716 6.6e-70 XK27_02470 K LytTr DNA-binding domain
IEMGHHED_00717 1.2e-18 S Sugar efflux transporter for intercellular exchange
IEMGHHED_00718 1.3e-250 dtpT U amino acid peptide transporter
IEMGHHED_00719 0.0 pepN 3.4.11.2 E aminopeptidase
IEMGHHED_00720 1.8e-46 lysM M LysM domain
IEMGHHED_00721 1.3e-174
IEMGHHED_00722 1.7e-152 mdtG EGP Major facilitator Superfamily
IEMGHHED_00723 6.9e-47 mdtG EGP Major facilitator Superfamily
IEMGHHED_00724 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00725 4.6e-88 ymdB S Macro domain protein
IEMGHHED_00727 2.2e-96 L Transposase
IEMGHHED_00728 4.8e-28
IEMGHHED_00731 4.3e-67 K Helix-turn-helix XRE-family like proteins
IEMGHHED_00732 3.3e-147 malG P ABC transporter permease
IEMGHHED_00733 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
IEMGHHED_00734 1.3e-213 malE G Bacterial extracellular solute-binding protein
IEMGHHED_00735 6.8e-209 msmX P Belongs to the ABC transporter superfamily
IEMGHHED_00736 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
IEMGHHED_00737 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
IEMGHHED_00738 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
IEMGHHED_00739 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
IEMGHHED_00740 0.0 fhaB M Rib/alpha-like repeat
IEMGHHED_00741 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00742 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
IEMGHHED_00743 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
IEMGHHED_00744 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
IEMGHHED_00745 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IEMGHHED_00746 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
IEMGHHED_00747 1.7e-184 G Transmembrane secretion effector
IEMGHHED_00748 6.1e-136 V ABC transporter transmembrane region
IEMGHHED_00749 2.9e-224 L transposase, IS605 OrfB family
IEMGHHED_00750 1.1e-75 V ABC transporter transmembrane region
IEMGHHED_00751 6.5e-64 L RelB antitoxin
IEMGHHED_00752 2.1e-131 cobQ S glutamine amidotransferase
IEMGHHED_00753 1.8e-81 M NlpC/P60 family
IEMGHHED_00756 2.6e-155
IEMGHHED_00757 7.8e-38
IEMGHHED_00758 2e-32
IEMGHHED_00759 6.2e-163 EG EamA-like transporter family
IEMGHHED_00760 5e-165 EG EamA-like transporter family
IEMGHHED_00761 1.2e-139 yicL EG EamA-like transporter family
IEMGHHED_00762 4.3e-107
IEMGHHED_00763 1.1e-110
IEMGHHED_00764 5.8e-186 XK27_05540 S DUF218 domain
IEMGHHED_00765 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
IEMGHHED_00766 4.7e-85
IEMGHHED_00767 3.9e-57
IEMGHHED_00768 4.7e-25 S Protein conserved in bacteria
IEMGHHED_00769 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
IEMGHHED_00770 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
IEMGHHED_00771 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IEMGHHED_00772 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IEMGHHED_00773 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEMGHHED_00776 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
IEMGHHED_00777 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
IEMGHHED_00778 1.8e-230 steT_1 E amino acid
IEMGHHED_00779 2.2e-139 puuD S peptidase C26
IEMGHHED_00781 0.0 kup P Transport of potassium into the cell
IEMGHHED_00782 7.3e-74
IEMGHHED_00783 2.1e-45 S PFAM Archaeal ATPase
IEMGHHED_00785 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEMGHHED_00786 5.9e-45
IEMGHHED_00787 2e-135 V HNH endonuclease
IEMGHHED_00788 6.4e-135 S PFAM Archaeal ATPase
IEMGHHED_00789 9.2e-248 yifK E Amino acid permease
IEMGHHED_00790 9.7e-234 cycA E Amino acid permease
IEMGHHED_00791 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IEMGHHED_00792 0.0 clpE O AAA domain (Cdc48 subfamily)
IEMGHHED_00793 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
IEMGHHED_00794 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_00795 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
IEMGHHED_00796 0.0 XK27_06780 V ABC transporter permease
IEMGHHED_00797 1.9e-36
IEMGHHED_00798 7.9e-291 ytgP S Polysaccharide biosynthesis protein
IEMGHHED_00799 2.7e-137 lysA2 M Glycosyl hydrolases family 25
IEMGHHED_00800 2.3e-133 S Protein of unknown function (DUF975)
IEMGHHED_00801 7.6e-177 pbpX2 V Beta-lactamase
IEMGHHED_00802 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
IEMGHHED_00803 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEMGHHED_00804 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
IEMGHHED_00805 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
IEMGHHED_00806 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
IEMGHHED_00807 4.1e-44
IEMGHHED_00808 1e-207 ywhK S Membrane
IEMGHHED_00809 1.5e-80 ykuL S (CBS) domain
IEMGHHED_00810 0.0 cadA P P-type ATPase
IEMGHHED_00811 2.8e-205 napA P Sodium/hydrogen exchanger family
IEMGHHED_00812 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
IEMGHHED_00813 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
IEMGHHED_00814 4.1e-276 V ABC transporter transmembrane region
IEMGHHED_00815 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
IEMGHHED_00816 5.4e-51
IEMGHHED_00817 4.2e-154 EGP Major facilitator Superfamily
IEMGHHED_00818 3e-111 ropB K Transcriptional regulator
IEMGHHED_00819 2.7e-120 S CAAX protease self-immunity
IEMGHHED_00820 1.6e-194 S DUF218 domain
IEMGHHED_00821 0.0 macB_3 V ABC transporter, ATP-binding protein
IEMGHHED_00822 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
IEMGHHED_00823 2.8e-100 S ECF transporter, substrate-specific component
IEMGHHED_00824 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
IEMGHHED_00825 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
IEMGHHED_00826 1.3e-282 xylG 3.6.3.17 S ABC transporter
IEMGHHED_00827 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
IEMGHHED_00828 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
IEMGHHED_00829 3.7e-159 yeaE S Aldo/keto reductase family
IEMGHHED_00830 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
IEMGHHED_00831 9.6e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IEMGHHED_00832 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
IEMGHHED_00833 9.4e-72
IEMGHHED_00834 8.2e-140 cof S haloacid dehalogenase-like hydrolase
IEMGHHED_00835 8.2e-230 pbuG S permease
IEMGHHED_00836 2.1e-76 S ABC-2 family transporter protein
IEMGHHED_00837 4.7e-60 S ABC-2 family transporter protein
IEMGHHED_00838 1.4e-72 V ABC transporter, ATP-binding protein
IEMGHHED_00839 3.3e-37
IEMGHHED_00840 2.5e-119 K helix_turn_helix, mercury resistance
IEMGHHED_00841 7.5e-231 pbuG S permease
IEMGHHED_00842 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
IEMGHHED_00843 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEMGHHED_00844 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
IEMGHHED_00846 1.9e-83 K Transcriptional regulator
IEMGHHED_00847 6.1e-61 K Transcriptional regulator
IEMGHHED_00848 2e-225 S cog cog1373
IEMGHHED_00849 9.7e-146 S haloacid dehalogenase-like hydrolase
IEMGHHED_00850 2.5e-226 pbuG S permease
IEMGHHED_00851 1.3e-41 L Transposase
IEMGHHED_00852 1.4e-37 S Putative adhesin
IEMGHHED_00853 2.6e-151 V ABC transporter transmembrane region
IEMGHHED_00854 4.6e-138
IEMGHHED_00855 1.8e-31
IEMGHHED_00858 2.4e-36
IEMGHHED_00859 2e-56 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IEMGHHED_00860 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
IEMGHHED_00861 0.0 copA 3.6.3.54 P P-type ATPase
IEMGHHED_00862 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
IEMGHHED_00863 1.2e-105
IEMGHHED_00864 7e-248 EGP Sugar (and other) transporter
IEMGHHED_00865 1.2e-18
IEMGHHED_00866 2.8e-210
IEMGHHED_00867 5.2e-91 S SLAP domain
IEMGHHED_00868 1.2e-28 S SLAP domain
IEMGHHED_00869 1.3e-117 S SLAP domain
IEMGHHED_00870 1.1e-106 S Bacteriocin helveticin-J
IEMGHHED_00871 1.2e-44
IEMGHHED_00872 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
IEMGHHED_00873 4e-32 E Zn peptidase
IEMGHHED_00874 3.9e-287 clcA P chloride
IEMGHHED_00875 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
IEMGHHED_00877 2.9e-12
IEMGHHED_00878 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEMGHHED_00880 8.2e-85 scrR K Periplasmic binding protein domain
IEMGHHED_00881 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
IEMGHHED_00883 5.5e-30
IEMGHHED_00884 4.3e-40 S Protein of unknown function (DUF2922)
IEMGHHED_00885 6.3e-132 S SLAP domain
IEMGHHED_00887 5.3e-41
IEMGHHED_00888 1.4e-76 K DNA-templated transcription, initiation
IEMGHHED_00889 9.7e-32 L Transposase
IEMGHHED_00890 3.7e-27 L Transposase
IEMGHHED_00891 9.1e-26
IEMGHHED_00892 2.1e-144 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IEMGHHED_00894 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IEMGHHED_00895 3.7e-100 S SLAP domain
IEMGHHED_00897 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
IEMGHHED_00898 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
IEMGHHED_00899 0.0 yjbQ P TrkA C-terminal domain protein
IEMGHHED_00900 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IEMGHHED_00901 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
IEMGHHED_00902 2.8e-12
IEMGHHED_00903 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
IEMGHHED_00904 5.7e-69 rplI J Binds to the 23S rRNA
IEMGHHED_00905 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
IEMGHHED_00906 1.4e-100
IEMGHHED_00907 2.1e-116
IEMGHHED_00908 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEMGHHED_00909 1.4e-98 G Aldose 1-epimerase
IEMGHHED_00910 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
IEMGHHED_00911 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEMGHHED_00912 0.0 XK27_08315 M Sulfatase
IEMGHHED_00913 2.8e-31 L Transposase
IEMGHHED_00914 8.4e-265 S Fibronectin type III domain
IEMGHHED_00915 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IEMGHHED_00916 3.4e-53
IEMGHHED_00918 4.6e-257 pepC 3.4.22.40 E aminopeptidase
IEMGHHED_00919 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEMGHHED_00920 1.7e-301 oppA E ABC transporter, substratebinding protein
IEMGHHED_00921 1.6e-310 oppA E ABC transporter, substratebinding protein
IEMGHHED_00922 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
IEMGHHED_00923 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEMGHHED_00924 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
IEMGHHED_00925 2.7e-199 oppD P Belongs to the ABC transporter superfamily
IEMGHHED_00926 1.9e-175 oppF P Belongs to the ABC transporter superfamily
IEMGHHED_00927 1.4e-256 pepC 3.4.22.40 E aminopeptidase
IEMGHHED_00928 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
IEMGHHED_00929 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
IEMGHHED_00930 2.6e-46 MA20_32385 Q 2-hydroxychromene-2-carboxylate isomerase
IEMGHHED_00931 6e-112
IEMGHHED_00933 3.9e-110 E Belongs to the SOS response-associated peptidase family
IEMGHHED_00934 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEMGHHED_00935 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
IEMGHHED_00936 2e-103 S TPM domain
IEMGHHED_00937 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IEMGHHED_00938 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IEMGHHED_00939 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IEMGHHED_00940 1e-147 tatD L hydrolase, TatD family
IEMGHHED_00941 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
IEMGHHED_00942 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
IEMGHHED_00943 4.5e-39 veg S Biofilm formation stimulator VEG
IEMGHHED_00944 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
IEMGHHED_00945 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IEMGHHED_00946 5.3e-80
IEMGHHED_00947 7.8e-292 S SLAP domain
IEMGHHED_00948 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IEMGHHED_00949 2.8e-34 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IEMGHHED_00950 4.2e-172 2.7.1.2 GK ROK family
IEMGHHED_00951 5.6e-43
IEMGHHED_00952 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
IEMGHHED_00953 1.4e-39 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_00954 1.6e-77 ybhL S Belongs to the BI1 family
IEMGHHED_00955 3.7e-101 potB E Binding-protein-dependent transport system inner membrane component
IEMGHHED_00956 1.5e-145 L PFAM transposase, IS4 family protein
IEMGHHED_00957 6.9e-69 S Domain of unknown function (DUF1934)
IEMGHHED_00958 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
IEMGHHED_00959 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
IEMGHHED_00960 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IEMGHHED_00961 1.8e-74 K acetyltransferase
IEMGHHED_00962 6.3e-284 pipD E Dipeptidase
IEMGHHED_00963 3.7e-156 msmR K AraC-like ligand binding domain
IEMGHHED_00964 6.4e-146 pbuX F xanthine permease
IEMGHHED_00965 5.6e-56 pbuX F xanthine permease
IEMGHHED_00966 9e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
IEMGHHED_00967 2.4e-43 K Helix-turn-helix
IEMGHHED_00968 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
IEMGHHED_00970 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
IEMGHHED_00971 3.6e-225 3.2.1.18 GH33 M Rib/alpha-like repeat
IEMGHHED_00972 3e-112 L PFAM transposase IS116 IS110 IS902
IEMGHHED_00973 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IEMGHHED_00975 6.8e-17
IEMGHHED_00976 3.7e-102 L Integrase
IEMGHHED_00977 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
IEMGHHED_00978 1.3e-30
IEMGHHED_00979 8.4e-96 L Transposase
IEMGHHED_00980 1.3e-141 yfeO P Voltage gated chloride channel
IEMGHHED_00981 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
IEMGHHED_00982 1.4e-51
IEMGHHED_00983 2.1e-42
IEMGHHED_00984 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IEMGHHED_00985 9.5e-297 ybeC E amino acid
IEMGHHED_00986 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
IEMGHHED_00987 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
IEMGHHED_00988 2.5e-39 rpmE2 J Ribosomal protein L31
IEMGHHED_00989 1.2e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
IEMGHHED_00990 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
IEMGHHED_00991 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
IEMGHHED_00992 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IEMGHHED_00993 2.2e-128 S (CBS) domain
IEMGHHED_00994 9.6e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IEMGHHED_00995 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
IEMGHHED_00996 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IEMGHHED_00997 1.6e-33 yabO J S4 domain protein
IEMGHHED_00998 6.8e-60 divIC D Septum formation initiator
IEMGHHED_00999 1.8e-62 yabR J S1 RNA binding domain
IEMGHHED_01000 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
IEMGHHED_01001 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IEMGHHED_01002 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IEMGHHED_01003 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IEMGHHED_01004 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
IEMGHHED_01005 1.4e-83 K FR47-like protein
IEMGHHED_01006 1.6e-08
IEMGHHED_01007 1.6e-08
IEMGHHED_01008 1.6e-08
IEMGHHED_01010 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
IEMGHHED_01011 1e-78 S helix_turn_helix, Deoxyribose operon repressor
IEMGHHED_01012 3.3e-140 repB EP Plasmid replication protein
IEMGHHED_01013 2.2e-22
IEMGHHED_01014 2.7e-182 L Transposase
IEMGHHED_01015 1.9e-89 ydiM G Major facilitator superfamily
IEMGHHED_01016 2.8e-46 MA20_41095
IEMGHHED_01017 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
IEMGHHED_01018 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEMGHHED_01019 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEMGHHED_01020 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
IEMGHHED_01021 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IEMGHHED_01022 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
IEMGHHED_01023 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IEMGHHED_01025 3.7e-27 L Transposase
IEMGHHED_01026 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
IEMGHHED_01027 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
IEMGHHED_01028 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
IEMGHHED_01029 1e-162 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEMGHHED_01031 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
IEMGHHED_01032 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
IEMGHHED_01033 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
IEMGHHED_01034 1.9e-19
IEMGHHED_01035 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
IEMGHHED_01036 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IEMGHHED_01037 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
IEMGHHED_01038 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
IEMGHHED_01039 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IEMGHHED_01040 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IEMGHHED_01041 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IEMGHHED_01042 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IEMGHHED_01043 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IEMGHHED_01044 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
IEMGHHED_01045 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IEMGHHED_01046 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IEMGHHED_01047 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IEMGHHED_01048 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IEMGHHED_01049 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEMGHHED_01050 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IEMGHHED_01051 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IEMGHHED_01052 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IEMGHHED_01053 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IEMGHHED_01054 2.3e-24 rpmD J Ribosomal protein L30
IEMGHHED_01055 1.3e-70 rplO J Binds to the 23S rRNA
IEMGHHED_01056 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
IEMGHHED_01057 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
IEMGHHED_01058 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IEMGHHED_01059 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
IEMGHHED_01060 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IEMGHHED_01061 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IEMGHHED_01062 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IEMGHHED_01063 1.4e-60 rplQ J Ribosomal protein L17
IEMGHHED_01064 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEMGHHED_01065 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEMGHHED_01066 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
IEMGHHED_01067 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
IEMGHHED_01068 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IEMGHHED_01069 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
IEMGHHED_01070 3.6e-183 L Phage integrase family
IEMGHHED_01071 1.8e-79
IEMGHHED_01072 1.2e-10
IEMGHHED_01073 1.4e-60 ymdB S YmdB-like protein
IEMGHHED_01074 3.7e-27 L Transposase
IEMGHHED_01075 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
IEMGHHED_01076 5.2e-170 degV S DegV family
IEMGHHED_01077 1.1e-135 V ABC transporter transmembrane region
IEMGHHED_01078 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
IEMGHHED_01080 1.4e-16
IEMGHHED_01081 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
IEMGHHED_01082 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEMGHHED_01083 6e-132 S membrane transporter protein
IEMGHHED_01084 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
IEMGHHED_01085 7.3e-161 czcD P cation diffusion facilitator family transporter
IEMGHHED_01086 1.4e-23
IEMGHHED_01087 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IEMGHHED_01088 5.4e-183 S AAA domain
IEMGHHED_01089 7.3e-44
IEMGHHED_01090 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
IEMGHHED_01091 4.1e-52
IEMGHHED_01092 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
IEMGHHED_01093 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IEMGHHED_01094 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IEMGHHED_01095 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
IEMGHHED_01096 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IEMGHHED_01097 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IEMGHHED_01098 1.2e-94 sigH K Belongs to the sigma-70 factor family
IEMGHHED_01099 1.7e-34
IEMGHHED_01100 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
IEMGHHED_01101 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IEMGHHED_01102 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
IEMGHHED_01103 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
IEMGHHED_01104 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IEMGHHED_01105 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
IEMGHHED_01106 2.8e-157 pstS P Phosphate
IEMGHHED_01107 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
IEMGHHED_01108 6.5e-154 pstA P Phosphate transport system permease protein PstA
IEMGHHED_01109 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEMGHHED_01110 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
IEMGHHED_01111 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
IEMGHHED_01113 1.2e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
IEMGHHED_01114 2.5e-38 L Protein of unknown function (DUF3991)
IEMGHHED_01115 1e-18 L Psort location Cytoplasmic, score
IEMGHHED_01116 1.9e-47 L Psort location Cytoplasmic, score
IEMGHHED_01117 3.4e-24 relB L Addiction module antitoxin, RelB DinJ family
IEMGHHED_01118 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
IEMGHHED_01120 9.9e-97 L Transposase
IEMGHHED_01121 1.3e-84 L Transposase
IEMGHHED_01122 1.5e-180 S Domain of unknown function (DUF389)
IEMGHHED_01123 1.5e-11 GT2,GT4 M family 8
IEMGHHED_01124 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IEMGHHED_01125 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
IEMGHHED_01126 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
IEMGHHED_01127 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
IEMGHHED_01128 9e-26
IEMGHHED_01129 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
IEMGHHED_01130 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IEMGHHED_01131 5.7e-106 2.4.1.58 GT8 M family 8
IEMGHHED_01132 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
IEMGHHED_01133 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IEMGHHED_01134 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IEMGHHED_01135 1.1e-34 S Protein of unknown function (DUF2508)
IEMGHHED_01136 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IEMGHHED_01137 8.9e-53 yaaQ S Cyclic-di-AMP receptor
IEMGHHED_01138 1.5e-155 holB 2.7.7.7 L DNA polymerase III
IEMGHHED_01139 1.8e-59 yabA L Involved in initiation control of chromosome replication
IEMGHHED_01140 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IEMGHHED_01141 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
IEMGHHED_01142 2.2e-85 S ECF transporter, substrate-specific component
IEMGHHED_01143 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
IEMGHHED_01144 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
IEMGHHED_01145 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IEMGHHED_01146 1.9e-245 L Transposase IS66 family
IEMGHHED_01147 8.7e-34 S Transposase C of IS166 homeodomain
IEMGHHED_01148 9.3e-64 L PFAM IS66 Orf2 family protein
IEMGHHED_01149 7.7e-22
IEMGHHED_01150 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IEMGHHED_01151 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
IEMGHHED_01152 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
IEMGHHED_01153 0.0 uup S ABC transporter, ATP-binding protein
IEMGHHED_01154 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
IEMGHHED_01156 5.8e-28 L An automated process has identified a potential problem with this gene model
IEMGHHED_01157 2.6e-25 S Uncharacterised protein family (UPF0236)
IEMGHHED_01158 2e-192 L COG2963 Transposase and inactivated derivatives
IEMGHHED_01159 2.9e-174 L Bifunctional protein
IEMGHHED_01160 1.2e-49 S Protein of unknown function (DUF3021)
IEMGHHED_01161 2.8e-65 K LytTr DNA-binding domain
IEMGHHED_01162 9.9e-97 L Transposase
IEMGHHED_01163 2.8e-140 sufC O FeS assembly ATPase SufC
IEMGHHED_01164 3.5e-174 sufD O FeS assembly protein SufD
IEMGHHED_01165 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IEMGHHED_01166 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
IEMGHHED_01167 2e-266 sufB O assembly protein SufB
IEMGHHED_01168 5.3e-45 yitW S Iron-sulfur cluster assembly protein
IEMGHHED_01169 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
IEMGHHED_01172 1.1e-183 scrR K helix_turn _helix lactose operon repressor
IEMGHHED_01173 3.7e-295 scrB 3.2.1.26 GH32 G invertase
IEMGHHED_01174 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
IEMGHHED_01175 2.3e-181 M CHAP domain
IEMGHHED_01176 3.5e-75
IEMGHHED_01177 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IEMGHHED_01178 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
IEMGHHED_01179 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IEMGHHED_01180 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IEMGHHED_01181 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
IEMGHHED_01182 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
IEMGHHED_01183 9.6e-41 yajC U Preprotein translocase
IEMGHHED_01184 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IEMGHHED_01185 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IEMGHHED_01186 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
IEMGHHED_01187 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
IEMGHHED_01188 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IEMGHHED_01189 2e-42 yrzL S Belongs to the UPF0297 family
IEMGHHED_01190 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IEMGHHED_01191 1.1e-50 yrzB S Belongs to the UPF0473 family
IEMGHHED_01192 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEMGHHED_01193 3.5e-54 trxA O Belongs to the thioredoxin family
IEMGHHED_01194 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
IEMGHHED_01195 1.1e-71 yslB S Protein of unknown function (DUF2507)
IEMGHHED_01196 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
IEMGHHED_01197 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IEMGHHED_01198 5.1e-10
IEMGHHED_01201 3.3e-127 L PFAM transposase IS116 IS110 IS902
IEMGHHED_01202 2.7e-141 L An automated process has identified a potential problem with this gene model
IEMGHHED_01203 2.2e-54 oppA E ABC transporter substrate-binding protein
IEMGHHED_01204 1.3e-149 oppA E ABC transporter substrate-binding protein
IEMGHHED_01205 9.6e-184 L DDE superfamily endonuclease
IEMGHHED_01206 5.4e-113
IEMGHHED_01207 1.7e-139
IEMGHHED_01208 6.9e-100 V ATPases associated with a variety of cellular activities
IEMGHHED_01209 3.7e-146 ykuT M mechanosensitive ion channel
IEMGHHED_01210 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
IEMGHHED_01211 1.3e-36
IEMGHHED_01213 2.5e-15
IEMGHHED_01214 1.5e-234 L Transposase DDE domain
IEMGHHED_01215 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
IEMGHHED_01216 3.2e-181 ccpA K catabolite control protein A
IEMGHHED_01217 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEMGHHED_01218 4.3e-55
IEMGHHED_01219 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
IEMGHHED_01220 2.1e-92 yutD S Protein of unknown function (DUF1027)
IEMGHHED_01221 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
IEMGHHED_01222 3.7e-100 S Protein of unknown function (DUF1461)
IEMGHHED_01223 6.8e-116 dedA S SNARE-like domain protein
IEMGHHED_01224 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
IEMGHHED_01225 2e-29 S O-antigen ligase like membrane protein
IEMGHHED_01226 1.1e-81 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
IEMGHHED_01227 5.3e-76 M Glycosyltransferase, group 1 family protein
IEMGHHED_01228 1.7e-42 M Glycosyl transferase family 2
IEMGHHED_01229 3e-270 L Transposase DDE domain
IEMGHHED_01257 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
IEMGHHED_01258 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
IEMGHHED_01259 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
IEMGHHED_01260 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEMGHHED_01261 1.7e-29 secG U Preprotein translocase
IEMGHHED_01262 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
IEMGHHED_01263 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
IEMGHHED_01264 8.7e-64 K Helix-turn-helix domain
IEMGHHED_01265 4.9e-111 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01268 8.8e-29
IEMGHHED_01270 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
IEMGHHED_01271 1.7e-129 manY G PTS system
IEMGHHED_01272 1e-173 manN G system, mannose fructose sorbose family IID component
IEMGHHED_01273 1.1e-62 manO S Domain of unknown function (DUF956)
IEMGHHED_01274 3.3e-158 K Transcriptional regulator
IEMGHHED_01275 1.3e-85 maa S transferase hexapeptide repeat
IEMGHHED_01276 1.7e-241 cycA E Amino acid permease
IEMGHHED_01277 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IEMGHHED_01278 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
IEMGHHED_01279 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
IEMGHHED_01280 7.3e-178 mtlR K Mga helix-turn-helix domain
IEMGHHED_01282 2.9e-23
IEMGHHED_01283 7.3e-211 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IEMGHHED_01285 1.3e-96 L Transposase
IEMGHHED_01286 5.1e-106 fabK 1.3.1.9 S Nitronate monooxygenase
IEMGHHED_01287 1.6e-82 2.8.3.1 I Coenzyme A transferase
IEMGHHED_01288 5.8e-151 2.8.3.1 I Coenzyme A transferase
IEMGHHED_01289 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
IEMGHHED_01290 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEMGHHED_01291 3.2e-75 S ECF transporter, substrate-specific component
IEMGHHED_01292 3.8e-80 coaA 2.7.1.33 F Pantothenic acid kinase
IEMGHHED_01293 1.4e-31 O OsmC-like protein
IEMGHHED_01295 1.5e-36 oppA E ABC transporter substrate-binding protein
IEMGHHED_01296 1.4e-09 K FCD
IEMGHHED_01297 4.7e-26 K FCD
IEMGHHED_01298 1.6e-60 clcA P chloride
IEMGHHED_01299 8.8e-41 clcA P chloride
IEMGHHED_01300 3.4e-134 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
IEMGHHED_01301 1.1e-23 S CAAX protease self-immunity
IEMGHHED_01303 4.1e-34
IEMGHHED_01304 1e-66 doc S Fic/DOC family
IEMGHHED_01306 9.4e-51 L An automated process has identified a potential problem with this gene model
IEMGHHED_01307 7.9e-16 L An automated process has identified a potential problem with this gene model
IEMGHHED_01308 1.3e-240 V N-6 DNA Methylase
IEMGHHED_01309 3.3e-86 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
IEMGHHED_01310 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
IEMGHHED_01311 1.7e-39 relB L RelB antitoxin
IEMGHHED_01313 2.9e-97 D VirC1 protein
IEMGHHED_01314 2.6e-67 L Transposase
IEMGHHED_01315 1.2e-160 mtlR K Mga helix-turn-helix domain
IEMGHHED_01316 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
IEMGHHED_01317 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01318 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
IEMGHHED_01319 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
IEMGHHED_01320 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
IEMGHHED_01321 2.1e-32
IEMGHHED_01322 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
IEMGHHED_01323 2.3e-156 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01324 3.9e-298 V ABC transporter transmembrane region
IEMGHHED_01325 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
IEMGHHED_01326 1.7e-193 S TerB-C domain
IEMGHHED_01327 3.7e-27 L Transposase
IEMGHHED_01328 2.5e-52 L Transposase
IEMGHHED_01329 1.3e-96 L Transposase
IEMGHHED_01330 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
IEMGHHED_01331 1.1e-47 S Peptidase propeptide and YPEB domain
IEMGHHED_01332 4.8e-138 L An automated process has identified a potential problem with this gene model
IEMGHHED_01334 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEMGHHED_01335 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IEMGHHED_01336 2.9e-96 L Transposase
IEMGHHED_01337 5.4e-60 L Resolvase, N-terminal
IEMGHHED_01338 1.6e-166 L Putative transposase DNA-binding domain
IEMGHHED_01339 1.2e-39 C 2Fe-2S iron-sulfur cluster binding domain
IEMGHHED_01340 6.4e-99 L Transposase
IEMGHHED_01341 6.8e-226 I Protein of unknown function (DUF2974)
IEMGHHED_01342 1.9e-116 yhiD S MgtC family
IEMGHHED_01344 1.4e-18 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01345 6.9e-64
IEMGHHED_01346 2.6e-84
IEMGHHED_01347 1.4e-134 D Ftsk spoiiie family protein
IEMGHHED_01348 5.1e-145 S Replication initiation factor
IEMGHHED_01349 3.9e-55
IEMGHHED_01350 2.3e-26
IEMGHHED_01351 9.5e-220 L Belongs to the 'phage' integrase family
IEMGHHED_01353 2.5e-62 yfiL V ABC transporter
IEMGHHED_01354 2.7e-34 V Transport permease protein
IEMGHHED_01355 2.6e-138 S TerB-C domain
IEMGHHED_01356 1.4e-245 P P-loop Domain of unknown function (DUF2791)
IEMGHHED_01357 0.0 lhr L DEAD DEAH box helicase
IEMGHHED_01358 1.4e-60
IEMGHHED_01359 4.3e-228 amtB P ammonium transporter
IEMGHHED_01360 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
IEMGHHED_01362 6.6e-61 psiE S Phosphate-starvation-inducible E
IEMGHHED_01363 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
IEMGHHED_01364 2.9e-69 S Iron-sulphur cluster biosynthesis
IEMGHHED_01366 2.3e-30
IEMGHHED_01367 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
IEMGHHED_01368 6.2e-12
IEMGHHED_01369 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01370 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01371 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01372 5.8e-78 M LysM domain protein
IEMGHHED_01373 4.7e-159 D nuclear chromosome segregation
IEMGHHED_01374 1.2e-105 G Phosphoglycerate mutase family
IEMGHHED_01375 2.6e-89 G Histidine phosphatase superfamily (branch 1)
IEMGHHED_01376 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
IEMGHHED_01377 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
IEMGHHED_01379 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
IEMGHHED_01381 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
IEMGHHED_01382 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
IEMGHHED_01383 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
IEMGHHED_01384 4.4e-144 K SIS domain
IEMGHHED_01385 4.8e-44 slpX S SLAP domain
IEMGHHED_01386 5.3e-167 slpX S SLAP domain
IEMGHHED_01387 1.3e-22 3.6.4.12 S transposase or invertase
IEMGHHED_01388 6.6e-11
IEMGHHED_01389 3.2e-240 npr 1.11.1.1 C NADH oxidase
IEMGHHED_01392 4.4e-239 oppA2 E ABC transporter, substratebinding protein
IEMGHHED_01393 3.4e-45 oppA2 E ABC transporter, substratebinding protein
IEMGHHED_01394 3.3e-179
IEMGHHED_01395 4.6e-123 gntR1 K UTRA
IEMGHHED_01396 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
IEMGHHED_01397 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
IEMGHHED_01398 1.7e-204 csaB M Glycosyl transferases group 1
IEMGHHED_01399 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IEMGHHED_01400 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
IEMGHHED_01401 1.4e-204 tnpB L Putative transposase DNA-binding domain
IEMGHHED_01402 0.0 pacL 3.6.3.8 P P-type ATPase
IEMGHHED_01403 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
IEMGHHED_01404 6e-258 epsU S Polysaccharide biosynthesis protein
IEMGHHED_01405 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
IEMGHHED_01406 4.1e-83 ydcK S Belongs to the SprT family
IEMGHHED_01408 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
IEMGHHED_01409 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
IEMGHHED_01410 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IEMGHHED_01411 5.8e-203 camS S sex pheromone
IEMGHHED_01412 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEMGHHED_01413 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
IEMGHHED_01414 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IEMGHHED_01415 2.7e-171 yegS 2.7.1.107 G Lipid kinase
IEMGHHED_01416 4.3e-108 ybhL S Belongs to the BI1 family
IEMGHHED_01417 2.6e-57
IEMGHHED_01418 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
IEMGHHED_01419 2.8e-244 nhaC C Na H antiporter NhaC
IEMGHHED_01420 6.3e-201 pbpX V Beta-lactamase
IEMGHHED_01421 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEMGHHED_01422 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
IEMGHHED_01427 1.9e-259 emrY EGP Major facilitator Superfamily
IEMGHHED_01428 2e-91 yxdD K Bacterial regulatory proteins, tetR family
IEMGHHED_01429 0.0 4.2.1.53 S Myosin-crossreactive antigen
IEMGHHED_01430 5.5e-148 S cog cog1373
IEMGHHED_01431 1.8e-98 L Transposase
IEMGHHED_01432 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
IEMGHHED_01433 2e-157 S reductase
IEMGHHED_01434 9.3e-35
IEMGHHED_01435 1.7e-87 L Transposase
IEMGHHED_01436 3.7e-27 L Transposase
IEMGHHED_01437 5e-78 K Putative DNA-binding domain
IEMGHHED_01438 4.8e-13 MA20_08550 S Tim44
IEMGHHED_01439 3.7e-27 L Transposase
IEMGHHED_01442 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IEMGHHED_01443 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
IEMGHHED_01444 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IEMGHHED_01445 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
IEMGHHED_01446 4e-40 S CRISPR-associated protein (Cas_Csn2)
IEMGHHED_01447 6.4e-69 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01448 2.2e-31 nuoG 1.6.5.3 C NADH-quinone oxidoreductase
IEMGHHED_01449 1.9e-22 K Putative DNA-binding domain
IEMGHHED_01450 7.6e-239 pyrP F Permease
IEMGHHED_01451 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IEMGHHED_01452 9.2e-262 emrY EGP Major facilitator Superfamily
IEMGHHED_01453 5.1e-155 mdtG EGP Major facilitator Superfamily
IEMGHHED_01454 1.2e-47 L Transposase, IS116 IS110 IS902 family
IEMGHHED_01455 4.7e-182 pepA E M42 glutamyl aminopeptidase
IEMGHHED_01456 2.2e-311 ybiT S ABC transporter, ATP-binding protein
IEMGHHED_01457 5.9e-174 S Aldo keto reductase
IEMGHHED_01458 2.7e-138
IEMGHHED_01459 2.8e-202 steT E amino acid
IEMGHHED_01460 2.1e-18 steT E amino acid
IEMGHHED_01461 8.6e-243 steT E amino acid
IEMGHHED_01462 2.8e-90 L An automated process has identified a potential problem with this gene model
IEMGHHED_01463 1.7e-10 U TIGRFAM filamentous haemagglutinin family outer membrane protein
IEMGHHED_01465 2.2e-129 blpT
IEMGHHED_01466 1.4e-107 M Transport protein ComB
IEMGHHED_01467 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
IEMGHHED_01468 5.8e-42 L Transposase
IEMGHHED_01469 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
IEMGHHED_01470 1.9e-147 glnH ET ABC transporter
IEMGHHED_01471 1.4e-80 K Transcriptional regulator, MarR family
IEMGHHED_01472 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
IEMGHHED_01473 0.0 V ABC transporter transmembrane region
IEMGHHED_01474 1.6e-100 S ABC-type cobalt transport system, permease component
IEMGHHED_01475 1e-246 G MFS/sugar transport protein
IEMGHHED_01476 9.8e-39 udk 2.7.1.48 F Zeta toxin
IEMGHHED_01477 3.8e-46 udk 2.7.1.48 F Zeta toxin
IEMGHHED_01478 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
IEMGHHED_01479 1.2e-146 glnH ET ABC transporter substrate-binding protein
IEMGHHED_01480 3.7e-90 gluC P ABC transporter permease
IEMGHHED_01481 4.7e-109 glnP P ABC transporter permease
IEMGHHED_01482 1.1e-164 S Protein of unknown function (DUF2974)
IEMGHHED_01483 5.6e-86
IEMGHHED_01484 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
IEMGHHED_01485 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01486 3.7e-30 S Fic/DOC family
IEMGHHED_01487 8.1e-175 ulaG S Beta-lactamase superfamily domain
IEMGHHED_01488 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
IEMGHHED_01489 1.3e-231 ulaA S PTS system sugar-specific permease component
IEMGHHED_01490 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
IEMGHHED_01491 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
IEMGHHED_01492 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
IEMGHHED_01493 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
IEMGHHED_01494 5.2e-68 L haloacid dehalogenase-like hydrolase
IEMGHHED_01495 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IEMGHHED_01496 1.4e-16 L Transposase
IEMGHHED_01497 1.9e-12 L Transposase
IEMGHHED_01498 5.9e-13 K Acetyltransferase (GNAT) domain
IEMGHHED_01499 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01500 6.9e-39 L An automated process has identified a potential problem with this gene model
IEMGHHED_01502 1.7e-230 G Bacterial extracellular solute-binding protein
IEMGHHED_01503 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
IEMGHHED_01504 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IEMGHHED_01505 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IEMGHHED_01506 0.0 kup P Transport of potassium into the cell
IEMGHHED_01507 9.1e-175 rihB 3.2.2.1 F Nucleoside
IEMGHHED_01508 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
IEMGHHED_01509 1.2e-154 S hydrolase
IEMGHHED_01510 2.5e-59 S Enterocin A Immunity
IEMGHHED_01511 9e-136 glcR K DeoR C terminal sensor domain
IEMGHHED_01512 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
IEMGHHED_01513 2e-160 rssA S Phospholipase, patatin family
IEMGHHED_01514 5.4e-147 S hydrolase
IEMGHHED_01515 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
IEMGHHED_01516 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
IEMGHHED_01517 1.6e-80
IEMGHHED_01518 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
IEMGHHED_01519 2.1e-39
IEMGHHED_01520 3.9e-119 C nitroreductase
IEMGHHED_01521 1.7e-249 yhdP S Transporter associated domain
IEMGHHED_01522 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
IEMGHHED_01523 0.0 1.3.5.4 C FAD binding domain
IEMGHHED_01524 1.1e-87 L PFAM transposase, IS4 family protein
IEMGHHED_01525 1.2e-49 L PFAM transposase, IS4 family protein
IEMGHHED_01526 1.7e-213 1.3.5.4 C FAD binding domain
IEMGHHED_01527 3.4e-126 1.3.5.4 C FAD binding domain
IEMGHHED_01528 3.2e-36 cheA 2.7.13.3 T ATP-binding region ATPase domain protein
IEMGHHED_01529 3.2e-24 pepM 5.4.2.9 G Phosphoenolpyruvate phosphomutase
IEMGHHED_01530 1.5e-25 S CAAX protease self-immunity
IEMGHHED_01531 1.4e-22 S CAAX protease self-immunity
IEMGHHED_01532 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01534 1.6e-96 ybaT E Amino acid permease
IEMGHHED_01535 1.7e-07 S LPXTG cell wall anchor motif
IEMGHHED_01536 4.4e-146 S Putative ABC-transporter type IV
IEMGHHED_01538 1.7e-27 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IEMGHHED_01539 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
IEMGHHED_01540 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEMGHHED_01541 1.2e-232 oppA E ABC transporter substrate-binding protein
IEMGHHED_01542 2.1e-95 oppA E ABC transporter substrate-binding protein
IEMGHHED_01543 3.2e-176 K AI-2E family transporter
IEMGHHED_01544 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
IEMGHHED_01545 4.1e-18
IEMGHHED_01546 4.1e-245 G Major Facilitator
IEMGHHED_01547 1.3e-79 E Zn peptidase
IEMGHHED_01548 1.2e-41 ps115 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01549 5.6e-45
IEMGHHED_01550 4.5e-66 S Bacteriocin helveticin-J
IEMGHHED_01551 1.7e-66 S SLAP domain
IEMGHHED_01552 5.8e-45
IEMGHHED_01553 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
IEMGHHED_01554 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
IEMGHHED_01555 1.7e-174 ABC-SBP S ABC transporter
IEMGHHED_01556 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEMGHHED_01557 1.6e-48 P CorA-like Mg2+ transporter protein
IEMGHHED_01558 5.2e-75 P CorA-like Mg2+ transporter protein
IEMGHHED_01559 3.5e-160 yvgN C Aldo keto reductase
IEMGHHED_01560 0.0 tetP J elongation factor G
IEMGHHED_01561 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
IEMGHHED_01562 1.2e-134 EGP Major facilitator Superfamily
IEMGHHED_01564 1.2e-38 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01565 9.7e-231 potE E amino acid
IEMGHHED_01566 9.9e-97 L Transposase
IEMGHHED_01567 4e-60 L Resolvase, N terminal domain
IEMGHHED_01568 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IEMGHHED_01569 2.6e-61 M Glycosyl hydrolases family 25
IEMGHHED_01570 1.3e-61 M Glycosyl hydrolases family 25
IEMGHHED_01571 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
IEMGHHED_01572 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01574 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
IEMGHHED_01575 1.6e-43 4.1.1.45 S Amidohydrolase
IEMGHHED_01576 3e-25 S Type I phosphodiesterase / nucleotide pyrophosphatase
IEMGHHED_01577 7e-87 gtcA S Teichoic acid glycosylation protein
IEMGHHED_01578 4.1e-80 fld C Flavodoxin
IEMGHHED_01579 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
IEMGHHED_01580 3.6e-163 yihY S Belongs to the UPF0761 family
IEMGHHED_01581 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
IEMGHHED_01582 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
IEMGHHED_01583 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
IEMGHHED_01584 2.1e-42 1.1.1.85 CE Isocitrate/isopropylmalate dehydrogenase
IEMGHHED_01585 6.7e-76 S Fic/DOC family
IEMGHHED_01586 1.9e-166 repA S Replication initiator protein A
IEMGHHED_01587 1.7e-142 soj D AAA domain
IEMGHHED_01588 1.3e-28
IEMGHHED_01589 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEMGHHED_01590 4.7e-70 L IS1381, transposase OrfA
IEMGHHED_01591 1.1e-109 tnpR1 L Resolvase, N terminal domain
IEMGHHED_01592 3.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEMGHHED_01593 9.3e-74 nrdI F NrdI Flavodoxin like
IEMGHHED_01594 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IEMGHHED_01595 1.9e-19 L Replication initiation factor
IEMGHHED_01596 9.4e-46
IEMGHHED_01597 1.8e-38 D Alpha beta
IEMGHHED_01598 1.4e-118 D Alpha beta
IEMGHHED_01599 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IEMGHHED_01600 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
IEMGHHED_01601 1.6e-85
IEMGHHED_01602 2.7e-74
IEMGHHED_01603 1.4e-140 hlyX S Transporter associated domain
IEMGHHED_01604 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IEMGHHED_01605 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
IEMGHHED_01606 0.0 clpE O Belongs to the ClpA ClpB family
IEMGHHED_01607 3.7e-27 L Transposase
IEMGHHED_01608 7.2e-44 ndhM C Molybdopterin-binding domain of aldehyde dehydrogenase
IEMGHHED_01609 5.3e-26
IEMGHHED_01610 8.5e-41 ptsH G phosphocarrier protein HPR
IEMGHHED_01611 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IEMGHHED_01612 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEMGHHED_01613 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
IEMGHHED_01614 1.4e-158 coiA 3.6.4.12 S Competence protein
IEMGHHED_01615 4.6e-114 yjbH Q Thioredoxin
IEMGHHED_01616 6.8e-110 yjbK S CYTH
IEMGHHED_01617 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
IEMGHHED_01618 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IEMGHHED_01619 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEMGHHED_01620 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
IEMGHHED_01621 4.2e-92 S SNARE associated Golgi protein
IEMGHHED_01622 1.1e-32 L An automated process has identified a potential problem with this gene model
IEMGHHED_01623 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
IEMGHHED_01624 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
IEMGHHED_01625 2.6e-214 yubA S AI-2E family transporter
IEMGHHED_01626 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
IEMGHHED_01627 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
IEMGHHED_01628 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
IEMGHHED_01629 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
IEMGHHED_01630 1.9e-236 S Peptidase M16
IEMGHHED_01631 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
IEMGHHED_01632 5.2e-97 ymfM S Helix-turn-helix domain
IEMGHHED_01633 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IEMGHHED_01634 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IEMGHHED_01635 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
IEMGHHED_01636 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
IEMGHHED_01637 5.1e-119 yvyE 3.4.13.9 S YigZ family
IEMGHHED_01638 4.7e-246 comFA L Helicase C-terminal domain protein
IEMGHHED_01639 9.4e-132 comFC S Competence protein
IEMGHHED_01640 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IEMGHHED_01641 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
IEMGHHED_01642 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IEMGHHED_01643 5.1e-17
IEMGHHED_01644 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IEMGHHED_01645 3.5e-157 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IEMGHHED_01646 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
IEMGHHED_01647 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
IEMGHHED_01648 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
IEMGHHED_01649 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
IEMGHHED_01650 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
IEMGHHED_01651 4.1e-90 S Short repeat of unknown function (DUF308)
IEMGHHED_01652 6.2e-165 rapZ S Displays ATPase and GTPase activities
IEMGHHED_01653 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
IEMGHHED_01654 2.1e-171 whiA K May be required for sporulation
IEMGHHED_01655 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
IEMGHHED_01656 0.0 S SH3-like domain
IEMGHHED_01657 4.9e-111 ybbL S ABC transporter, ATP-binding protein
IEMGHHED_01658 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
IEMGHHED_01660 5.7e-58 1.13.12.16 S Nitronate monooxygenase
IEMGHHED_01661 3.1e-48 S Domain of unknown function (DUF4811)
IEMGHHED_01662 1.4e-262 lmrB EGP Major facilitator Superfamily
IEMGHHED_01663 4.2e-77 K MerR HTH family regulatory protein
IEMGHHED_01664 3.1e-139 S Cysteine-rich secretory protein family
IEMGHHED_01665 4.6e-274 ycaM E amino acid
IEMGHHED_01666 6.3e-290
IEMGHHED_01668 3.3e-189 cggR K Putative sugar-binding domain
IEMGHHED_01669 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
IEMGHHED_01670 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
IEMGHHED_01671 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
IEMGHHED_01672 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
IEMGHHED_01673 1.2e-94
IEMGHHED_01674 3.4e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
IEMGHHED_01675 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IEMGHHED_01676 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
IEMGHHED_01677 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
IEMGHHED_01678 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
IEMGHHED_01679 3.5e-163 murB 1.3.1.98 M Cell wall formation
IEMGHHED_01680 3.5e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
IEMGHHED_01681 1.3e-129 potB P ABC transporter permease
IEMGHHED_01682 4.8e-127 potC P ABC transporter permease
IEMGHHED_01683 7.3e-208 potD P ABC transporter
IEMGHHED_01684 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
IEMGHHED_01685 2e-172 ybbR S YbbR-like protein
IEMGHHED_01686 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IEMGHHED_01687 1.4e-147 S hydrolase
IEMGHHED_01688 1.8e-75 K Penicillinase repressor
IEMGHHED_01689 1.6e-118
IEMGHHED_01690 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IEMGHHED_01691 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
IEMGHHED_01692 1e-190 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01693 5.9e-12 S Scaffold protein B
IEMGHHED_01694 8.3e-143 licT K CAT RNA binding domain
IEMGHHED_01695 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
IEMGHHED_01696 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEMGHHED_01697 1e-149 D Alpha beta
IEMGHHED_01698 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
IEMGHHED_01699 2.4e-34 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
IEMGHHED_01700 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
IEMGHHED_01701 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
IEMGHHED_01702 8.2e-36
IEMGHHED_01703 2.2e-90 2.7.7.65 T GGDEF domain
IEMGHHED_01704 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IEMGHHED_01706 2e-310 E Amino acid permease
IEMGHHED_01707 5.8e-100 L Helix-turn-helix domain
IEMGHHED_01708 1.3e-160 L hmm pf00665
IEMGHHED_01710 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IEMGHHED_01711 3.5e-101 ylbE GM NAD(P)H-binding
IEMGHHED_01712 7.6e-94 S VanZ like family
IEMGHHED_01713 8.9e-133 yebC K Transcriptional regulatory protein
IEMGHHED_01714 1.7e-179 comGA NU Type II IV secretion system protein
IEMGHHED_01715 1.7e-171 comGB NU type II secretion system
IEMGHHED_01716 3.1e-43 comGC U competence protein ComGC
IEMGHHED_01717 1.8e-69
IEMGHHED_01718 2.3e-41
IEMGHHED_01719 3.8e-77 comGF U Putative Competence protein ComGF
IEMGHHED_01720 1.6e-21
IEMGHHED_01721 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
IEMGHHED_01722 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IEMGHHED_01724 8.5e-151 L Belongs to the 'phage' integrase family
IEMGHHED_01725 2.6e-09 S Pfam:DUF955
IEMGHHED_01726 2.2e-25 K Helix-turn-helix domain
IEMGHHED_01727 1.3e-20 XK27_07105 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01728 1.3e-30 K Helix-turn-helix domain
IEMGHHED_01730 4.1e-09 S Arc-like DNA binding domain
IEMGHHED_01732 4e-21 K Conserved phage C-terminus (Phg_2220_C)
IEMGHHED_01733 1.5e-26 S Domain of unknown function (DUF771)
IEMGHHED_01741 3.6e-34 S Phage derived protein Gp49-like (DUF891)
IEMGHHED_01742 7.1e-35 K Helix-turn-helix XRE-family like proteins
IEMGHHED_01744 1.1e-188 L N-6 DNA Methylase
IEMGHHED_01745 2.2e-26 S Type I restriction modification DNA specificity domain
IEMGHHED_01746 5.7e-11 S Single-strand binding protein family
IEMGHHED_01752 1.1e-15 S SLAP domain
IEMGHHED_01754 1.4e-24 srtA 3.4.22.70 M sortase family
IEMGHHED_01756 5.6e-40 M domain protein
IEMGHHED_01757 6.7e-15 S SLAP domain
IEMGHHED_01758 8.4e-33 M domain protein
IEMGHHED_01762 1.8e-141 U TraM recognition site of TraD and TraG
IEMGHHED_01763 3.9e-32 I mechanosensitive ion channel activity
IEMGHHED_01765 8.4e-15
IEMGHHED_01766 1.8e-159 trsE S COG0433 Predicted ATPase
IEMGHHED_01767 1.2e-32 M Peptidase family M23
IEMGHHED_01770 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
IEMGHHED_01773 1.5e-80
IEMGHHED_01774 1.6e-73 marR K Transcriptional regulator, MarR family
IEMGHHED_01775 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IEMGHHED_01776 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEMGHHED_01777 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IEMGHHED_01778 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
IEMGHHED_01779 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
IEMGHHED_01780 2.9e-107 IQ reductase
IEMGHHED_01781 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
IEMGHHED_01782 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
IEMGHHED_01783 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
IEMGHHED_01784 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
IEMGHHED_01785 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IEMGHHED_01786 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
IEMGHHED_01787 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
IEMGHHED_01788 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
IEMGHHED_01789 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEMGHHED_01792 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
IEMGHHED_01793 1.3e-273 E amino acid
IEMGHHED_01794 0.0 L Helicase C-terminal domain protein
IEMGHHED_01795 2.4e-204 pbpX1 V Beta-lactamase
IEMGHHED_01796 5.1e-226 N Uncharacterized conserved protein (DUF2075)
IEMGHHED_01797 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
IEMGHHED_01798 2.5e-89 M Protein of unknown function (DUF3737)
IEMGHHED_01799 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
IEMGHHED_01800 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
IEMGHHED_01801 7.7e-67 S SdpI/YhfL protein family
IEMGHHED_01802 4.8e-131 K Transcriptional regulatory protein, C terminal
IEMGHHED_01803 1.6e-266 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
IEMGHHED_01804 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
IEMGHHED_01805 1.8e-12 vanZ V VanZ like family
IEMGHHED_01806 1.7e-16 vanZ V VanZ like family
IEMGHHED_01807 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
IEMGHHED_01808 4.9e-217 EGP Major facilitator Superfamily
IEMGHHED_01809 1.7e-195 ampC V Beta-lactamase
IEMGHHED_01812 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
IEMGHHED_01813 1.7e-113 tdk 2.7.1.21 F thymidine kinase
IEMGHHED_01814 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IEMGHHED_01815 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
IEMGHHED_01816 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
IEMGHHED_01817 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IEMGHHED_01818 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
IEMGHHED_01819 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEMGHHED_01820 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IEMGHHED_01821 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IEMGHHED_01822 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IEMGHHED_01823 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IEMGHHED_01824 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IEMGHHED_01825 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
IEMGHHED_01826 2e-30 ywzB S Protein of unknown function (DUF1146)
IEMGHHED_01827 1.2e-177 mbl D Cell shape determining protein MreB Mrl
IEMGHHED_01828 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
IEMGHHED_01829 3.3e-33 S Protein of unknown function (DUF2969)
IEMGHHED_01830 4.7e-216 rodA D Belongs to the SEDS family
IEMGHHED_01831 1.8e-78 usp6 T universal stress protein
IEMGHHED_01832 8.4e-39
IEMGHHED_01833 6.3e-238 rarA L recombination factor protein RarA
IEMGHHED_01834 1.3e-84 yueI S Protein of unknown function (DUF1694)
IEMGHHED_01835 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IEMGHHED_01836 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IEMGHHED_01837 6.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
IEMGHHED_01838 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IEMGHHED_01839 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
IEMGHHED_01840 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEMGHHED_01841 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
IEMGHHED_01842 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
IEMGHHED_01843 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
IEMGHHED_01844 1.5e-94 S Protein of unknown function (DUF3990)
IEMGHHED_01845 6.5e-44
IEMGHHED_01847 0.0 3.6.3.8 P P-type ATPase
IEMGHHED_01848 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
IEMGHHED_01849 2.5e-52
IEMGHHED_01850 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
IEMGHHED_01851 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
IEMGHHED_01852 5.7e-126 S Haloacid dehalogenase-like hydrolase
IEMGHHED_01853 6.6e-108 radC L DNA repair protein
IEMGHHED_01854 2.4e-176 mreB D cell shape determining protein MreB
IEMGHHED_01855 2e-147 mreC M Involved in formation and maintenance of cell shape
IEMGHHED_01856 2.7e-94 mreD
IEMGHHED_01858 6.4e-54 S Protein of unknown function (DUF3397)
IEMGHHED_01859 6.3e-78 mraZ K Belongs to the MraZ family
IEMGHHED_01860 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
IEMGHHED_01861 1.8e-54 ftsL D Cell division protein FtsL
IEMGHHED_01862 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
IEMGHHED_01863 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IEMGHHED_01864 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IEMGHHED_01865 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IEMGHHED_01866 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
IEMGHHED_01867 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
IEMGHHED_01868 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IEMGHHED_01869 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
IEMGHHED_01870 1.7e-45 yggT S YGGT family
IEMGHHED_01871 5.7e-149 ylmH S S4 domain protein
IEMGHHED_01872 2.8e-74 gpsB D DivIVA domain protein
IEMGHHED_01873 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IEMGHHED_01874 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
IEMGHHED_01875 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
IEMGHHED_01876 6.7e-37
IEMGHHED_01877 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IEMGHHED_01878 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
IEMGHHED_01879 5.4e-56 XK27_04120 S Putative amino acid metabolism
IEMGHHED_01880 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
IEMGHHED_01881 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
IEMGHHED_01882 8.3e-106 S Repeat protein
IEMGHHED_01883 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
IEMGHHED_01884 1.6e-294 L Nuclease-related domain
IEMGHHED_01885 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
IEMGHHED_01886 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEMGHHED_01887 3.5e-32 ykzG S Belongs to the UPF0356 family
IEMGHHED_01888 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
IEMGHHED_01889 0.0 typA T GTP-binding protein TypA
IEMGHHED_01890 5.9e-211 ftsW D Belongs to the SEDS family
IEMGHHED_01891 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
IEMGHHED_01892 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
IEMGHHED_01893 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IEMGHHED_01894 2.4e-187 ylbL T Belongs to the peptidase S16 family
IEMGHHED_01895 3.1e-79 comEA L Competence protein ComEA
IEMGHHED_01896 2.3e-30 comEC S Competence protein ComEC
IEMGHHED_01897 0.0 comEC S Competence protein ComEC
IEMGHHED_01898 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
IEMGHHED_01899 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
IEMGHHED_01900 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IEMGHHED_01901 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IEMGHHED_01902 1.3e-148
IEMGHHED_01903 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IEMGHHED_01904 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
IEMGHHED_01905 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IEMGHHED_01906 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
IEMGHHED_01907 7.8e-39 yjeM E Amino Acid
IEMGHHED_01908 3.4e-175 yjeM E Amino Acid
IEMGHHED_01909 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IEMGHHED_01910 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
IEMGHHED_01911 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
IEMGHHED_01912 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
IEMGHHED_01913 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
IEMGHHED_01914 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IEMGHHED_01915 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
IEMGHHED_01916 2.7e-216 aspC 2.6.1.1 E Aminotransferase
IEMGHHED_01917 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IEMGHHED_01918 2.1e-194 pbpX1 V Beta-lactamase
IEMGHHED_01919 1.2e-299 I Protein of unknown function (DUF2974)
IEMGHHED_01920 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01921 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
IEMGHHED_01922 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEMGHHED_01923 1.5e-203 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
IEMGHHED_01924 6.8e-156 ypbG 2.7.1.2 GK ROK family
IEMGHHED_01925 1.8e-73 C nitroreductase
IEMGHHED_01926 1.9e-70 S Domain of unknown function (DUF4767)
IEMGHHED_01927 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
IEMGHHED_01928 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
IEMGHHED_01929 3.2e-101 3.6.1.27 I Acid phosphatase homologues
IEMGHHED_01930 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01931 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
IEMGHHED_01933 2e-178 MA20_14895 S Conserved hypothetical protein 698
IEMGHHED_01934 1.1e-83 dps P Belongs to the Dps family
IEMGHHED_01935 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
IEMGHHED_01936 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
IEMGHHED_01937 1.8e-58 S Putative adhesin
IEMGHHED_01938 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
IEMGHHED_01939 2e-234 mepA V MATE efflux family protein
IEMGHHED_01940 4.9e-40 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01941 2.9e-72 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01942 2.9e-12 L Transposase and inactivated derivatives, IS30 family
IEMGHHED_01943 2.4e-10 L Psort location Cytoplasmic, score
IEMGHHED_01944 8.9e-92 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
IEMGHHED_01945 2.8e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
IEMGHHED_01946 1.7e-218 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
IEMGHHED_01948 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
IEMGHHED_01949 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
IEMGHHED_01950 1.4e-36 S Cytochrome B5
IEMGHHED_01951 6e-168 arbZ I Phosphate acyltransferases
IEMGHHED_01952 1.6e-182 arbY M Glycosyl transferase family 8
IEMGHHED_01953 5e-184 arbY M Glycosyl transferase family 8
IEMGHHED_01954 5e-156 arbx M Glycosyl transferase family 8
IEMGHHED_01955 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
IEMGHHED_01957 4.9e-34
IEMGHHED_01959 4.8e-131 K response regulator
IEMGHHED_01960 2.2e-305 vicK 2.7.13.3 T Histidine kinase
IEMGHHED_01961 1.6e-257 yycH S YycH protein
IEMGHHED_01962 3.4e-149 yycI S YycH protein
IEMGHHED_01963 4.1e-147 vicX 3.1.26.11 S domain protein
IEMGHHED_01964 1.6e-161 htrA 3.4.21.107 O serine protease
IEMGHHED_01965 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IEMGHHED_01966 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
IEMGHHED_01967 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IEMGHHED_01968 2.2e-120 lsa S ABC transporter
IEMGHHED_01969 2.7e-83 S Protein of unknown function (DUF1211)
IEMGHHED_01970 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
IEMGHHED_01971 2.8e-119 3.6.1.55 F NUDIX domain
IEMGHHED_01972 1.5e-245 brnQ U Component of the transport system for branched-chain amino acids
IEMGHHED_01973 0.0 L Plasmid pRiA4b ORF-3-like protein
IEMGHHED_01974 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IEMGHHED_01975 2.5e-08 S Protein of unknown function (DUF3021)
IEMGHHED_01976 9e-34 K Bacterial regulatory helix-turn-helix protein, lysR family
IEMGHHED_01978 4.2e-63 lmrB EGP Major facilitator Superfamily
IEMGHHED_01979 2.9e-122 rbtT P Major Facilitator Superfamily
IEMGHHED_01980 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
IEMGHHED_01981 2.5e-86 K GNAT family
IEMGHHED_01982 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
IEMGHHED_01984 4.3e-36
IEMGHHED_01985 6.2e-288 P ABC transporter
IEMGHHED_01986 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_01987 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_01988 1.2e-250 yifK E Amino acid permease
IEMGHHED_01989 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IEMGHHED_01990 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IEMGHHED_01991 0.0 aha1 P E1-E2 ATPase
IEMGHHED_01992 2.4e-175 F DNA/RNA non-specific endonuclease
IEMGHHED_01993 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
IEMGHHED_01994 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IEMGHHED_01995 3.4e-73 metI P ABC transporter permease
IEMGHHED_01996 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
IEMGHHED_01997 1.9e-261 frdC 1.3.5.4 C FAD binding domain
IEMGHHED_01998 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
IEMGHHED_01999 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
IEMGHHED_02000 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
IEMGHHED_02001 5.7e-272 P Sodium:sulfate symporter transmembrane region
IEMGHHED_02002 1.7e-153 ydjP I Alpha/beta hydrolase family
IEMGHHED_02003 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
IEMGHHED_02004 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
IEMGHHED_02005 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
IEMGHHED_02006 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
IEMGHHED_02007 9.3e-72 yeaL S Protein of unknown function (DUF441)
IEMGHHED_02008 3.5e-21
IEMGHHED_02009 3.6e-146 cbiQ P cobalt transport
IEMGHHED_02010 0.0 ykoD P ABC transporter, ATP-binding protein
IEMGHHED_02011 1.5e-95 S UPF0397 protein
IEMGHHED_02012 2.9e-66 S Domain of unknown function DUF1828
IEMGHHED_02013 5.5e-09
IEMGHHED_02014 1.5e-50
IEMGHHED_02015 2.6e-177 citR K Putative sugar-binding domain
IEMGHHED_02016 6.5e-249 yjjP S Putative threonine/serine exporter
IEMGHHED_02018 5.9e-37 M domain protein
IEMGHHED_02019 4.9e-142 L Transposase
IEMGHHED_02020 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IEMGHHED_02021 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
IEMGHHED_02022 8.5e-60
IEMGHHED_02023 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IEMGHHED_02024 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
IEMGHHED_02025 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
IEMGHHED_02026 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
IEMGHHED_02027 1.2e-222 patA 2.6.1.1 E Aminotransferase
IEMGHHED_02028 3.7e-27 L Transposase
IEMGHHED_02030 8.4e-25 G Peptidase_C39 like family
IEMGHHED_02031 2.8e-162 M NlpC/P60 family
IEMGHHED_02032 6.5e-91 G Peptidase_C39 like family
IEMGHHED_02033 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
IEMGHHED_02034 2.8e-77 P Cobalt transport protein
IEMGHHED_02035 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
IEMGHHED_02036 1.3e-173 K helix_turn_helix, arabinose operon control protein
IEMGHHED_02037 8.3e-157 htpX O Belongs to the peptidase M48B family
IEMGHHED_02038 5.1e-96 lemA S LemA family
IEMGHHED_02039 7.5e-192 ybiR P Citrate transporter
IEMGHHED_02040 2e-70 S Iron-sulphur cluster biosynthesis
IEMGHHED_02041 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
IEMGHHED_02042 1.2e-17
IEMGHHED_02043 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IEMGHHED_02044 4.8e-34 S reductase
IEMGHHED_02045 4.4e-39 S reductase
IEMGHHED_02046 2.7e-32 S reductase
IEMGHHED_02047 1.3e-148 yxeH S hydrolase
IEMGHHED_02048 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IEMGHHED_02049 1.1e-243 yfnA E Amino Acid
IEMGHHED_02050 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
IEMGHHED_02051 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
IEMGHHED_02052 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IEMGHHED_02053 2.2e-292 I Acyltransferase
IEMGHHED_02054 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
IEMGHHED_02055 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
IEMGHHED_02056 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
IEMGHHED_02057 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
IEMGHHED_02058 6.1e-131 sip L Belongs to the 'phage' integrase family
IEMGHHED_02061 1.6e-22 S Hypothetical protein (DUF2513)
IEMGHHED_02062 7.4e-20 S Pfam:Peptidase_M78
IEMGHHED_02063 2.8e-20 ps115 K sequence-specific DNA binding
IEMGHHED_02066 1.4e-16
IEMGHHED_02067 6.7e-75 ps308 K AntA/AntB antirepressor
IEMGHHED_02068 2.5e-14
IEMGHHED_02074 5e-30 S HNH endonuclease
IEMGHHED_02075 6.1e-70 S AAA domain
IEMGHHED_02077 2.1e-151 res L Helicase C-terminal domain protein
IEMGHHED_02079 4.2e-42 S Protein of unknown function (DUF669)
IEMGHHED_02080 1.4e-272 S Phage plasmid primase, P4
IEMGHHED_02092 3.3e-37 S VRR_NUC
IEMGHHED_02094 3.4e-18
IEMGHHED_02095 5.3e-43 S HNH endonuclease
IEMGHHED_02096 4.6e-52 S Phage terminase, small subunit
IEMGHHED_02098 2.6e-22 V HNH endonuclease
IEMGHHED_02099 1.7e-228 S Phage Terminase
IEMGHHED_02101 1.5e-134 S Phage portal protein
IEMGHHED_02102 1.8e-66 S Clp protease
IEMGHHED_02103 2.6e-145 S peptidase activity
IEMGHHED_02104 1.9e-21 S Phage gp6-like head-tail connector protein
IEMGHHED_02106 8.8e-11 S Bacteriophage HK97-gp10, putative tail-component
IEMGHHED_02108 3.1e-13 S Pfam:Phage_TTP_1
IEMGHHED_02111 3.8e-134 xkdO D NLP P60 protein
IEMGHHED_02112 7.9e-31 S phage tail
IEMGHHED_02113 2e-249 S Phage minor structural protein
IEMGHHED_02115 7.9e-12 S Domain of unknown function (DUF2479)
IEMGHHED_02117 1.4e-17 GT2,GT4 LM gp58-like protein
IEMGHHED_02121 4.9e-24
IEMGHHED_02123 1.4e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
IEMGHHED_02124 1.3e-115 M hydrolase, family 25
IEMGHHED_02126 6.8e-10
IEMGHHED_02127 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
IEMGHHED_02128 2.3e-23 S Protein of unknown function (DUF2929)
IEMGHHED_02129 0.0 dnaE 2.7.7.7 L DNA polymerase
IEMGHHED_02130 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
IEMGHHED_02131 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
IEMGHHED_02132 1e-167 cvfB S S1 domain
IEMGHHED_02133 2.9e-165 xerD D recombinase XerD
IEMGHHED_02134 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEMGHHED_02135 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IEMGHHED_02136 1.6e-103 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IEMGHHED_02137 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
IEMGHHED_02138 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IEMGHHED_02139 2.7e-18 M Lysin motif
IEMGHHED_02140 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
IEMGHHED_02141 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
IEMGHHED_02142 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
IEMGHHED_02143 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
IEMGHHED_02144 3.9e-229 S Tetratricopeptide repeat protein
IEMGHHED_02145 3.1e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IEMGHHED_02146 1e-78 rimL J Acetyltransferase (GNAT) domain
IEMGHHED_02147 9.7e-133 S Alpha/beta hydrolase family
IEMGHHED_02148 6.4e-99 L Transposase
IEMGHHED_02149 1.3e-34 L Transposase
IEMGHHED_02150 1.7e-33 yxaM EGP Major facilitator Superfamily
IEMGHHED_02151 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
IEMGHHED_02152 1e-79 S AAA domain
IEMGHHED_02153 3.3e-61 3.6.1.55 F NUDIX domain
IEMGHHED_02154 1.9e-138 2.4.2.3 F Phosphorylase superfamily
IEMGHHED_02155 9e-144 2.4.2.3 F Phosphorylase superfamily
IEMGHHED_02156 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
IEMGHHED_02157 9.7e-65 yagE E amino acid
IEMGHHED_02158 8.4e-128 yagE E Amino acid permease
IEMGHHED_02159 4.3e-86 3.4.21.96 S SLAP domain
IEMGHHED_02160 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEMGHHED_02161 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
IEMGHHED_02162 1.2e-107 hlyIII S protein, hemolysin III
IEMGHHED_02163 2e-144 DegV S Uncharacterised protein, DegV family COG1307
IEMGHHED_02164 7.1e-36 yozE S Belongs to the UPF0346 family
IEMGHHED_02165 1.1e-66 yjcE P NhaP-type Na H and K H
IEMGHHED_02166 1.5e-40 yjcE P Sodium proton antiporter
IEMGHHED_02167 1.9e-94 yjcE P Sodium proton antiporter
IEMGHHED_02168 8.1e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IEMGHHED_02169 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IEMGHHED_02170 5.8e-152 dprA LU DNA protecting protein DprA
IEMGHHED_02171 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IEMGHHED_02172 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
IEMGHHED_02173 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
IEMGHHED_02174 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IEMGHHED_02175 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IEMGHHED_02176 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
IEMGHHED_02177 1.4e-86 C Aldo keto reductase
IEMGHHED_02178 3.8e-48 M LysM domain protein
IEMGHHED_02179 2.9e-15 M LysM domain protein
IEMGHHED_02180 4.4e-118 L hmm pf00665
IEMGHHED_02181 1.4e-98 L Helix-turn-helix domain
IEMGHHED_02182 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
IEMGHHED_02183 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEMGHHED_02184 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IEMGHHED_02185 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IEMGHHED_02186 1.4e-115 mmuP E amino acid
IEMGHHED_02187 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
IEMGHHED_02188 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
IEMGHHED_02189 1.7e-284 E Amino acid permease
IEMGHHED_02190 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
IEMGHHED_02191 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
IEMGHHED_02192 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
IEMGHHED_02193 9.9e-82 C Flavodoxin
IEMGHHED_02194 4.8e-61 uvrA3 L excinuclease ABC, A subunit
IEMGHHED_02195 0.0 uvrA3 L excinuclease ABC, A subunit
IEMGHHED_02196 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
IEMGHHED_02197 2.1e-114 3.6.1.27 I Acid phosphatase homologues
IEMGHHED_02198 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
IEMGHHED_02199 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
IEMGHHED_02200 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
IEMGHHED_02201 9.3e-204 pbpX1 V Beta-lactamase
IEMGHHED_02202 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
IEMGHHED_02203 7.5e-95 S ECF-type riboflavin transporter, S component
IEMGHHED_02204 1.3e-229 S Putative peptidoglycan binding domain
IEMGHHED_02205 9e-83 K Acetyltransferase (GNAT) domain
IEMGHHED_02206 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IEMGHHED_02207 2.5e-191 yrvN L AAA C-terminal domain
IEMGHHED_02208 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
IEMGHHED_02209 6.8e-153 treB G phosphotransferase system
IEMGHHED_02210 4.5e-111 treB G phosphotransferase system
IEMGHHED_02211 1.2e-100 treR K UTRA
IEMGHHED_02212 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
IEMGHHED_02213 5.7e-18
IEMGHHED_02214 1.5e-239 G Bacterial extracellular solute-binding protein
IEMGHHED_02215 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
IEMGHHED_02216 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
IEMGHHED_02218 0.0 S SLAP domain
IEMGHHED_02219 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
IEMGHHED_02220 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
IEMGHHED_02221 3.4e-42 S RloB-like protein
IEMGHHED_02222 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
IEMGHHED_02223 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
IEMGHHED_02224 1.2e-63 S SIR2-like domain
IEMGHHED_02225 3.2e-10 S Domain of unknown function DUF87
IEMGHHED_02226 2e-75 S cog cog0433
IEMGHHED_02227 1.9e-110 F DNA/RNA non-specific endonuclease
IEMGHHED_02228 2.7e-34 S YSIRK type signal peptide
IEMGHHED_02230 5.5e-53
IEMGHHED_02231 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
IEMGHHED_02232 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IEMGHHED_02233 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
IEMGHHED_02234 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
IEMGHHED_02235 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
IEMGHHED_02236 0.0 FbpA K Fibronectin-binding protein
IEMGHHED_02237 1.1e-66
IEMGHHED_02238 1.3e-159 degV S EDD domain protein, DegV family
IEMGHHED_02239 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
IEMGHHED_02240 5.4e-203 xerS L Belongs to the 'phage' integrase family
IEMGHHED_02241 4.1e-67
IEMGHHED_02242 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
IEMGHHED_02243 5.8e-211 M Glycosyl hydrolases family 25
IEMGHHED_02244 4.5e-189 ydaM M Glycosyl transferase
IEMGHHED_02245 4e-177 G Glycosyl hydrolases family 8
IEMGHHED_02246 1e-119 yfbR S HD containing hydrolase-like enzyme
IEMGHHED_02247 6.4e-159 L HNH nucleases
IEMGHHED_02248 7.3e-148 S Protein of unknown function (DUF805)
IEMGHHED_02249 3.4e-135 glnQ E ABC transporter, ATP-binding protein
IEMGHHED_02250 6.7e-290 glnP P ABC transporter permease
IEMGHHED_02251 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
IEMGHHED_02252 5.8e-64 yeaO S Protein of unknown function, DUF488
IEMGHHED_02253 1.3e-124 terC P Integral membrane protein TerC family
IEMGHHED_02254 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
IEMGHHED_02255 8.5e-133 cobB K SIR2 family
IEMGHHED_02256 2.1e-39 S Transglycosylase associated protein
IEMGHHED_02257 6.9e-122 yoaK S Protein of unknown function (DUF1275)
IEMGHHED_02258 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
IEMGHHED_02259 1.3e-12 L TIGRFAM transposase, IS605 OrfB family
IEMGHHED_02260 1.2e-11 S Transposase C of IS166 homeodomain
IEMGHHED_02261 1.4e-59 XK27_01125 L IS66 Orf2 like protein
IEMGHHED_02263 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
IEMGHHED_02264 2.8e-182 K Transcriptional regulator
IEMGHHED_02265 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEMGHHED_02266 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
IEMGHHED_02267 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
IEMGHHED_02268 0.0 snf 2.7.11.1 KL domain protein
IEMGHHED_02269 5.8e-15
IEMGHHED_02270 2e-35
IEMGHHED_02272 3.8e-104 pncA Q Isochorismatase family
IEMGHHED_02273 4.9e-118
IEMGHHED_02276 3.6e-63
IEMGHHED_02277 1.4e-34
IEMGHHED_02278 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
IEMGHHED_02279 3.4e-79
IEMGHHED_02280 1e-242 cpdA S Calcineurin-like phosphoesterase
IEMGHHED_02281 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
IEMGHHED_02282 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
IEMGHHED_02283 1e-107 ypsA S Belongs to the UPF0398 family
IEMGHHED_02284 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
IEMGHHED_02285 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
IEMGHHED_02286 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IEMGHHED_02287 1.3e-114 dnaD L DnaD domain protein
IEMGHHED_02288 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
IEMGHHED_02289 2.4e-89 ypmB S Protein conserved in bacteria
IEMGHHED_02290 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
IEMGHHED_02291 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
IEMGHHED_02292 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
IEMGHHED_02293 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
IEMGHHED_02294 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
IEMGHHED_02295 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
IEMGHHED_02296 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
IEMGHHED_02297 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
IEMGHHED_02298 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
IEMGHHED_02299 9.7e-169
IEMGHHED_02300 7.5e-143
IEMGHHED_02301 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
IEMGHHED_02302 1.4e-26
IEMGHHED_02303 6.7e-145
IEMGHHED_02304 5.1e-137
IEMGHHED_02305 4.5e-141
IEMGHHED_02306 9.6e-124 skfE V ATPases associated with a variety of cellular activities
IEMGHHED_02307 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
IEMGHHED_02308 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
IEMGHHED_02309 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IEMGHHED_02310 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
IEMGHHED_02311 4.8e-81 mutT 3.6.1.55 F NUDIX domain
IEMGHHED_02312 1.4e-127 S Peptidase family M23
IEMGHHED_02313 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
IEMGHHED_02314 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
IEMGHHED_02315 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
IEMGHHED_02316 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
IEMGHHED_02317 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
IEMGHHED_02318 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IEMGHHED_02319 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IEMGHHED_02320 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
IEMGHHED_02321 3.5e-71 yqeY S YqeY-like protein
IEMGHHED_02322 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
IEMGHHED_02323 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
IEMGHHED_02324 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
IEMGHHED_02325 1.3e-116 S Peptidase family M23
IEMGHHED_02326 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IEMGHHED_02328 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
IEMGHHED_02329 9.4e-118
IEMGHHED_02330 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
IEMGHHED_02331 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
IEMGHHED_02332 2.6e-280 thrC 4.2.3.1 E Threonine synthase
IEMGHHED_02333 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
IEMGHHED_02334 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
IEMGHHED_02335 0.0 L PLD-like domain
IEMGHHED_02336 4.8e-42 S SnoaL-like domain
IEMGHHED_02337 5.4e-53 hipB K sequence-specific DNA binding
IEMGHHED_02338 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
IEMGHHED_02339 3.4e-27
IEMGHHED_02340 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_02341 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
IEMGHHED_02342 9.4e-124 L Transposase
IEMGHHED_02343 1.4e-94

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)