ORF_ID e_value Gene_name EC_number CAZy COGs Description
NPLLMNCH_00001 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NPLLMNCH_00002 9.5e-31
NPLLMNCH_00003 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
NPLLMNCH_00004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
NPLLMNCH_00005 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NPLLMNCH_00006 3.5e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPLLMNCH_00007 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
NPLLMNCH_00008 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
NPLLMNCH_00009 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NPLLMNCH_00010 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
NPLLMNCH_00011 2.6e-35 yaaA S S4 domain protein YaaA
NPLLMNCH_00012 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NPLLMNCH_00013 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPLLMNCH_00014 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NPLLMNCH_00015 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
NPLLMNCH_00016 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
NPLLMNCH_00017 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NPLLMNCH_00018 4.5e-189 ydaM M Glycosyl transferase
NPLLMNCH_00019 4e-177 G Glycosyl hydrolases family 8
NPLLMNCH_00020 1e-119 yfbR S HD containing hydrolase-like enzyme
NPLLMNCH_00021 6.4e-159 L HNH nucleases
NPLLMNCH_00022 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
NPLLMNCH_00023 1e-48 S Metal binding domain of Ada
NPLLMNCH_00025 2.3e-43 ybhL S Belongs to the BI1 family
NPLLMNCH_00027 7.9e-210 S Bacterial protein of unknown function (DUF871)
NPLLMNCH_00028 1.2e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NPLLMNCH_00029 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
NPLLMNCH_00030 1.5e-102 srtA 3.4.22.70 M sortase family
NPLLMNCH_00031 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_00032 5.9e-24
NPLLMNCH_00033 2.1e-173 M Glycosyl hydrolases family 25
NPLLMNCH_00034 5e-29
NPLLMNCH_00035 7.9e-19
NPLLMNCH_00037 1.1e-07
NPLLMNCH_00038 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
NPLLMNCH_00039 3.2e-38
NPLLMNCH_00044 1.6e-36
NPLLMNCH_00045 1.1e-08
NPLLMNCH_00046 6.5e-125 Z012_12235 S Baseplate J-like protein
NPLLMNCH_00047 9.5e-33
NPLLMNCH_00048 1.2e-48
NPLLMNCH_00049 5.7e-104
NPLLMNCH_00050 2.1e-46
NPLLMNCH_00051 1.2e-58 M LysM domain
NPLLMNCH_00052 0.0 3.4.14.13 M Phage tail tape measure protein TP901
NPLLMNCH_00054 9e-27
NPLLMNCH_00055 4e-56
NPLLMNCH_00056 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
NPLLMNCH_00057 8e-57
NPLLMNCH_00058 2.9e-45
NPLLMNCH_00059 1.5e-75
NPLLMNCH_00060 1.6e-30 S Protein of unknown function (DUF4054)
NPLLMNCH_00061 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
NPLLMNCH_00062 1.6e-58
NPLLMNCH_00063 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
NPLLMNCH_00064 1.1e-07 S Lysin motif
NPLLMNCH_00065 1e-97 S Phage Mu protein F like protein
NPLLMNCH_00066 7e-142 S Protein of unknown function (DUF1073)
NPLLMNCH_00067 5.4e-230 S Terminase-like family
NPLLMNCH_00068 1.5e-28 L Terminase small subunit
NPLLMNCH_00069 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
NPLLMNCH_00070 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
NPLLMNCH_00078 2.1e-14
NPLLMNCH_00079 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
NPLLMNCH_00085 2.3e-49 dnaC L IstB-like ATP binding protein
NPLLMNCH_00086 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
NPLLMNCH_00087 6.5e-57 S Protein of unknown function (DUF1071)
NPLLMNCH_00092 1.8e-07 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00093 7.2e-10
NPLLMNCH_00097 4.3e-98 S AntA/AntB antirepressor
NPLLMNCH_00098 2.9e-12
NPLLMNCH_00103 1.3e-81 S DNA binding
NPLLMNCH_00104 9.5e-12 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00105 6.5e-23 K Cro/C1-type HTH DNA-binding domain
NPLLMNCH_00106 3.3e-18 S Pfam:Peptidase_M78
NPLLMNCH_00111 1.6e-20 S YjcQ protein
NPLLMNCH_00112 4.2e-180 sip L Belongs to the 'phage' integrase family
NPLLMNCH_00113 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_00114 5.9e-24
NPLLMNCH_00115 2.1e-173 M Glycosyl hydrolases family 25
NPLLMNCH_00116 5e-29
NPLLMNCH_00117 7.9e-19
NPLLMNCH_00119 1.1e-07
NPLLMNCH_00120 2.2e-19 S Phage uncharacterised protein (Phage_XkdX)
NPLLMNCH_00121 3.2e-38
NPLLMNCH_00126 1.6e-36
NPLLMNCH_00127 1.1e-08
NPLLMNCH_00128 6.5e-125 Z012_12235 S Baseplate J-like protein
NPLLMNCH_00129 9.5e-33
NPLLMNCH_00130 1.2e-48
NPLLMNCH_00131 5.7e-104
NPLLMNCH_00132 2.1e-46
NPLLMNCH_00133 1.2e-58 M LysM domain
NPLLMNCH_00134 0.0 3.4.14.13 M Phage tail tape measure protein TP901
NPLLMNCH_00136 9e-27
NPLLMNCH_00137 4e-56
NPLLMNCH_00138 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
NPLLMNCH_00139 8e-57
NPLLMNCH_00140 2.9e-45
NPLLMNCH_00141 1.5e-75
NPLLMNCH_00142 1.6e-30 S Protein of unknown function (DUF4054)
NPLLMNCH_00143 3.5e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
NPLLMNCH_00144 1.6e-58
NPLLMNCH_00145 3.9e-87 S Uncharacterized protein conserved in bacteria (DUF2213)
NPLLMNCH_00146 1.1e-07 S Lysin motif
NPLLMNCH_00147 1e-97 S Phage Mu protein F like protein
NPLLMNCH_00148 7e-142 S Protein of unknown function (DUF1073)
NPLLMNCH_00149 5.4e-230 S Terminase-like family
NPLLMNCH_00150 1.5e-28 L Terminase small subunit
NPLLMNCH_00151 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
NPLLMNCH_00152 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
NPLLMNCH_00160 2.1e-14
NPLLMNCH_00161 1.2e-40 rusA 3.1.22.4 L Endodeoxyribonuclease RusA
NPLLMNCH_00167 2.3e-49 dnaC L IstB-like ATP binding protein
NPLLMNCH_00168 2.7e-34 S Conserved phage C-terminus (Phg_2220_C)
NPLLMNCH_00169 6.5e-57 S Protein of unknown function (DUF1071)
NPLLMNCH_00174 1.8e-07 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00175 7.2e-10
NPLLMNCH_00179 4.3e-98 S AntA/AntB antirepressor
NPLLMNCH_00180 2.9e-12
NPLLMNCH_00185 1.3e-81 S DNA binding
NPLLMNCH_00186 9.5e-12 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00187 6.5e-23 K Cro/C1-type HTH DNA-binding domain
NPLLMNCH_00188 3.3e-18 S Pfam:Peptidase_M78
NPLLMNCH_00193 1.6e-20 S YjcQ protein
NPLLMNCH_00194 2.3e-178 sip L Belongs to the 'phage' integrase family
NPLLMNCH_00195 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
NPLLMNCH_00196 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NPLLMNCH_00197 0.0 dnaK O Heat shock 70 kDa protein
NPLLMNCH_00198 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NPLLMNCH_00199 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
NPLLMNCH_00200 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
NPLLMNCH_00201 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NPLLMNCH_00202 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NPLLMNCH_00203 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NPLLMNCH_00204 3.2e-47 rplGA J ribosomal protein
NPLLMNCH_00205 8.8e-47 ylxR K Protein of unknown function (DUF448)
NPLLMNCH_00206 1.4e-196 nusA K Participates in both transcription termination and antitermination
NPLLMNCH_00207 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
NPLLMNCH_00208 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPLLMNCH_00209 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
NPLLMNCH_00210 1.7e-195 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
NPLLMNCH_00211 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
NPLLMNCH_00212 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NPLLMNCH_00213 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
NPLLMNCH_00214 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
NPLLMNCH_00215 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NPLLMNCH_00216 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
NPLLMNCH_00217 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
NPLLMNCH_00218 2.9e-116 plsC 2.3.1.51 I Acyltransferase
NPLLMNCH_00219 1.1e-222 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
NPLLMNCH_00220 0.0 pepO 3.4.24.71 O Peptidase family M13
NPLLMNCH_00221 0.0 mdlB V ABC transporter
NPLLMNCH_00222 0.0 mdlA V ABC transporter
NPLLMNCH_00223 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
NPLLMNCH_00224 3e-38 ynzC S UPF0291 protein
NPLLMNCH_00225 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NPLLMNCH_00226 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
NPLLMNCH_00227 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
NPLLMNCH_00228 4.6e-213 S SLAP domain
NPLLMNCH_00229 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
NPLLMNCH_00230 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
NPLLMNCH_00231 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NPLLMNCH_00232 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
NPLLMNCH_00233 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NPLLMNCH_00234 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NPLLMNCH_00235 2.7e-258 yfnA E amino acid
NPLLMNCH_00236 0.0 V FtsX-like permease family
NPLLMNCH_00237 4.1e-133 cysA V ABC transporter, ATP-binding protein
NPLLMNCH_00238 3.4e-23
NPLLMNCH_00240 2.5e-288 pipD E Dipeptidase
NPLLMNCH_00241 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
NPLLMNCH_00242 0.0 smc D Required for chromosome condensation and partitioning
NPLLMNCH_00243 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
NPLLMNCH_00244 2.1e-308 oppA E ABC transporter substrate-binding protein
NPLLMNCH_00245 3.1e-240 oppA E ABC transporter substrate-binding protein
NPLLMNCH_00246 2.8e-134 S Uncharacterised protein family (UPF0236)
NPLLMNCH_00247 9.7e-46 oppA E ABC transporter substrate-binding protein
NPLLMNCH_00248 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
NPLLMNCH_00249 2.6e-172 oppB P ABC transporter permease
NPLLMNCH_00250 1.5e-170 oppF P Belongs to the ABC transporter superfamily
NPLLMNCH_00251 1.1e-192 oppD P Belongs to the ABC transporter superfamily
NPLLMNCH_00252 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPLLMNCH_00253 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
NPLLMNCH_00254 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NPLLMNCH_00255 2.2e-304 yloV S DAK2 domain fusion protein YloV
NPLLMNCH_00256 4e-57 asp S Asp23 family, cell envelope-related function
NPLLMNCH_00257 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
NPLLMNCH_00259 1.8e-87 M hydrolase, family 25
NPLLMNCH_00260 7.6e-39 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NPLLMNCH_00267 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
NPLLMNCH_00268 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
NPLLMNCH_00269 1.6e-55 L Phage terminase, small subunit
NPLLMNCH_00270 3.5e-49 L HNH nucleases
NPLLMNCH_00272 3.1e-14 arpU S Phage transcriptional regulator, ArpU family
NPLLMNCH_00273 9.8e-12
NPLLMNCH_00275 3.3e-37 S VRR_NUC
NPLLMNCH_00286 2.7e-268 S Phage plasmid primase, P4
NPLLMNCH_00287 1.7e-30 S Protein of unknown function (DUF669)
NPLLMNCH_00288 1.4e-147 res L Helicase C-terminal domain protein
NPLLMNCH_00290 1.6e-70 S AAA domain
NPLLMNCH_00296 3.5e-46
NPLLMNCH_00297 4.4e-79 S Phage antirepressor protein KilAC domain
NPLLMNCH_00298 4.7e-18 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00300 2.2e-15 E Pfam:DUF955
NPLLMNCH_00302 9.9e-118 L Belongs to the 'phage' integrase family
NPLLMNCH_00303 1.4e-30
NPLLMNCH_00304 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
NPLLMNCH_00305 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
NPLLMNCH_00306 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
NPLLMNCH_00307 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
NPLLMNCH_00308 1.1e-138 stp 3.1.3.16 T phosphatase
NPLLMNCH_00309 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NPLLMNCH_00310 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NPLLMNCH_00311 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NPLLMNCH_00312 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
NPLLMNCH_00313 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
NPLLMNCH_00314 1.1e-77 6.3.3.2 S ASCH
NPLLMNCH_00315 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
NPLLMNCH_00316 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
NPLLMNCH_00317 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPLLMNCH_00318 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPLLMNCH_00319 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
NPLLMNCH_00320 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NPLLMNCH_00321 5.3e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NPLLMNCH_00322 3.4e-71 yqhY S Asp23 family, cell envelope-related function
NPLLMNCH_00323 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPLLMNCH_00324 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPLLMNCH_00325 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
NPLLMNCH_00326 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
NPLLMNCH_00327 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPLLMNCH_00328 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
NPLLMNCH_00330 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
NPLLMNCH_00331 4.3e-298 S Predicted membrane protein (DUF2207)
NPLLMNCH_00332 1.2e-155 cinI S Serine hydrolase (FSH1)
NPLLMNCH_00333 1e-205 M Glycosyl hydrolases family 25
NPLLMNCH_00335 8.5e-178 I Carboxylesterase family
NPLLMNCH_00336 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
NPLLMNCH_00337 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_00338 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_00339 1.7e-148 S haloacid dehalogenase-like hydrolase
NPLLMNCH_00340 7e-50
NPLLMNCH_00341 1.9e-37
NPLLMNCH_00342 1.2e-63 S Alpha beta hydrolase
NPLLMNCH_00343 1e-23 S Alpha beta hydrolase
NPLLMNCH_00344 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
NPLLMNCH_00345 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
NPLLMNCH_00346 7.1e-46
NPLLMNCH_00347 3.1e-148 glcU U sugar transport
NPLLMNCH_00348 3.7e-250 lctP C L-lactate permease
NPLLMNCH_00349 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
NPLLMNCH_00350 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPLLMNCH_00351 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
NPLLMNCH_00352 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
NPLLMNCH_00353 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPLLMNCH_00354 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
NPLLMNCH_00355 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
NPLLMNCH_00356 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NPLLMNCH_00357 1.5e-102 GM NmrA-like family
NPLLMNCH_00359 2e-57 clcA P chloride
NPLLMNCH_00360 1.6e-106 L PFAM Integrase catalytic
NPLLMNCH_00361 1.3e-284 lsa S ABC transporter
NPLLMNCH_00362 2.4e-44
NPLLMNCH_00363 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
NPLLMNCH_00364 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
NPLLMNCH_00365 9.7e-52 S Iron-sulfur cluster assembly protein
NPLLMNCH_00366 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NPLLMNCH_00367 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
NPLLMNCH_00368 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
NPLLMNCH_00369 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPLLMNCH_00370 3.3e-275 yjeM E Amino Acid
NPLLMNCH_00371 5.8e-83 S Fic/DOC family
NPLLMNCH_00372 2.7e-285
NPLLMNCH_00373 3.2e-77
NPLLMNCH_00374 2.3e-87 S Protein of unknown function (DUF805)
NPLLMNCH_00375 5.6e-68 O OsmC-like protein
NPLLMNCH_00376 9.4e-209 EGP Major facilitator Superfamily
NPLLMNCH_00377 2.5e-215 sptS 2.7.13.3 T Histidine kinase
NPLLMNCH_00378 6.4e-24 K response regulator
NPLLMNCH_00379 6.4e-71 scrR K Periplasmic binding protein domain
NPLLMNCH_00380 5.5e-36
NPLLMNCH_00381 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
NPLLMNCH_00382 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
NPLLMNCH_00383 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NPLLMNCH_00384 0.0 lacZ 3.2.1.23 G -beta-galactosidase
NPLLMNCH_00385 0.0 lacS G Transporter
NPLLMNCH_00386 3.2e-165 lacR K Transcriptional regulator
NPLLMNCH_00387 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
NPLLMNCH_00388 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
NPLLMNCH_00389 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
NPLLMNCH_00390 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
NPLLMNCH_00391 2e-106 K Transcriptional regulator, AbiEi antitoxin
NPLLMNCH_00392 1.2e-188 K Periplasmic binding protein-like domain
NPLLMNCH_00393 7.3e-148 S Protein of unknown function (DUF805)
NPLLMNCH_00394 3.4e-135 glnQ E ABC transporter, ATP-binding protein
NPLLMNCH_00395 6.7e-290 glnP P ABC transporter permease
NPLLMNCH_00396 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
NPLLMNCH_00397 5.8e-64 yeaO S Protein of unknown function, DUF488
NPLLMNCH_00398 1.3e-124 terC P Integral membrane protein TerC family
NPLLMNCH_00399 9.2e-92 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
NPLLMNCH_00400 5.8e-73 S domain protein
NPLLMNCH_00402 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
NPLLMNCH_00403 3e-145 potD2 P ABC transporter
NPLLMNCH_00404 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPLLMNCH_00405 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
NPLLMNCH_00406 1.5e-36 oppA E ABC transporter substrate-binding protein
NPLLMNCH_00408 1.4e-31 O OsmC-like protein
NPLLMNCH_00409 3.8e-80 coaA 2.7.1.33 F Pantothenic acid kinase
NPLLMNCH_00410 3.2e-75 S ECF transporter, substrate-specific component
NPLLMNCH_00411 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPLLMNCH_00412 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
NPLLMNCH_00413 5.8e-151 2.8.3.1 I Coenzyme A transferase
NPLLMNCH_00414 1.6e-82 2.8.3.1 I Coenzyme A transferase
NPLLMNCH_00415 9.3e-151 fabK 1.3.1.9 S Nitronate monooxygenase
NPLLMNCH_00416 6.1e-111 crt 4.2.1.17 I Enoyl-CoA hydratase/isomerase
NPLLMNCH_00417 3.5e-108 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPLLMNCH_00418 1.4e-107 yisY 1.11.1.10 S Alpha/beta hydrolase family
NPLLMNCH_00419 2.8e-125 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPLLMNCH_00420 7.7e-110 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NPLLMNCH_00421 5.7e-24 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NPLLMNCH_00422 2.2e-67 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
NPLLMNCH_00423 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NPLLMNCH_00424 2.1e-120 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
NPLLMNCH_00425 3.1e-56 G Xylose isomerase domain protein TIM barrel
NPLLMNCH_00426 8.4e-90 nanK GK ROK family
NPLLMNCH_00427 2.6e-123 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
NPLLMNCH_00428 3.7e-66 K Helix-turn-helix domain, rpiR family
NPLLMNCH_00429 7.1e-263 E ABC transporter, substratebinding protein
NPLLMNCH_00430 9.1e-10 K peptidyl-tyrosine sulfation
NPLLMNCH_00432 1.2e-128 S interspecies interaction between organisms
NPLLMNCH_00433 2.7e-34
NPLLMNCH_00436 1.9e-21
NPLLMNCH_00437 6e-148
NPLLMNCH_00438 6.7e-170
NPLLMNCH_00439 2e-263 glnA 6.3.1.2 E glutamine synthetase
NPLLMNCH_00440 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
NPLLMNCH_00441 1.2e-166 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NPLLMNCH_00442 1.5e-65 yqhL P Rhodanese-like protein
NPLLMNCH_00443 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
NPLLMNCH_00444 4e-119 gluP 3.4.21.105 S Rhomboid family
NPLLMNCH_00445 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NPLLMNCH_00446 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
NPLLMNCH_00447 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
NPLLMNCH_00448 0.0 S membrane
NPLLMNCH_00449 2e-169 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
NPLLMNCH_00450 1.3e-38 S RelB antitoxin
NPLLMNCH_00451 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NPLLMNCH_00452 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPLLMNCH_00453 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
NPLLMNCH_00454 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NPLLMNCH_00455 8.7e-159 isdE P Periplasmic binding protein
NPLLMNCH_00456 6.3e-123 M Iron Transport-associated domain
NPLLMNCH_00457 3e-09 isdH M Iron Transport-associated domain
NPLLMNCH_00458 2.2e-89
NPLLMNCH_00459 2.2e-113 S SLAP domain
NPLLMNCH_00460 2.6e-51 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPLLMNCH_00461 5.7e-46 S An automated process has identified a potential problem with this gene model
NPLLMNCH_00462 3e-137 S Protein of unknown function (DUF3100)
NPLLMNCH_00463 4e-245 3.5.1.47 S Peptidase dimerisation domain
NPLLMNCH_00464 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
NPLLMNCH_00465 0.0 oppA E ABC transporter
NPLLMNCH_00466 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
NPLLMNCH_00467 0.0 mco Q Multicopper oxidase
NPLLMNCH_00468 1.9e-25
NPLLMNCH_00469 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
NPLLMNCH_00470 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
NPLLMNCH_00471 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPLLMNCH_00472 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPLLMNCH_00473 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPLLMNCH_00474 1.9e-89 ydiM G Major facilitator superfamily
NPLLMNCH_00475 8.1e-91 cjaA ET ABC transporter substrate-binding protein
NPLLMNCH_00476 3e-53 cjaA ET ABC transporter substrate-binding protein
NPLLMNCH_00477 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPLLMNCH_00478 2e-110 P ABC transporter permease
NPLLMNCH_00479 3.6e-109 papP P ABC transporter, permease protein
NPLLMNCH_00481 8.8e-62 yodB K Transcriptional regulator, HxlR family
NPLLMNCH_00482 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPLLMNCH_00483 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
NPLLMNCH_00484 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
NPLLMNCH_00485 1.5e-72 S Aminoacyl-tRNA editing domain
NPLLMNCH_00486 1.2e-54 S Abi-like protein
NPLLMNCH_00487 8e-224 S SLAP domain
NPLLMNCH_00488 3.9e-128 S CAAX protease self-immunity
NPLLMNCH_00489 1.3e-277 arlS 2.7.13.3 T Histidine kinase
NPLLMNCH_00490 1.2e-126 K response regulator
NPLLMNCH_00491 4.7e-97 yceD S Uncharacterized ACR, COG1399
NPLLMNCH_00492 1.7e-215 ylbM S Belongs to the UPF0348 family
NPLLMNCH_00493 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
NPLLMNCH_00494 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
NPLLMNCH_00495 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NPLLMNCH_00496 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
NPLLMNCH_00497 4.2e-84 yqeG S HAD phosphatase, family IIIA
NPLLMNCH_00498 9.2e-201 tnpB L Putative transposase DNA-binding domain
NPLLMNCH_00499 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NPLLMNCH_00500 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NPLLMNCH_00501 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
NPLLMNCH_00502 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NPLLMNCH_00503 4e-98 rihB 3.2.2.1 F Nucleoside
NPLLMNCH_00504 3.7e-101 potB E Binding-protein-dependent transport system inner membrane component
NPLLMNCH_00505 3.9e-23 S domain protein
NPLLMNCH_00506 1.7e-168 V ABC transporter
NPLLMNCH_00507 7.7e-39 S Protein of unknown function (DUF3021)
NPLLMNCH_00508 4.2e-53 K LytTr DNA-binding domain
NPLLMNCH_00511 3e-107 L Transposase
NPLLMNCH_00512 1.3e-96 L Transposase
NPLLMNCH_00513 1.5e-180 S Domain of unknown function (DUF389)
NPLLMNCH_00514 4.3e-75
NPLLMNCH_00515 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NPLLMNCH_00516 1.3e-168 dnaI L Primosomal protein DnaI
NPLLMNCH_00517 5.1e-251 dnaB L Replication initiation and membrane attachment
NPLLMNCH_00518 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NPLLMNCH_00519 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NPLLMNCH_00520 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
NPLLMNCH_00521 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NPLLMNCH_00522 3.5e-25 qmcA O prohibitin homologues
NPLLMNCH_00523 7.4e-105 qmcA O prohibitin homologues
NPLLMNCH_00524 8e-51 L RelB antitoxin
NPLLMNCH_00525 4.5e-188 S Bacteriocin helveticin-J
NPLLMNCH_00526 4.4e-283 M Peptidase family M1 domain
NPLLMNCH_00527 1.8e-176 S SLAP domain
NPLLMNCH_00528 6.9e-218 mepA V MATE efflux family protein
NPLLMNCH_00529 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
NPLLMNCH_00530 1.7e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
NPLLMNCH_00531 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
NPLLMNCH_00533 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
NPLLMNCH_00534 6.5e-221 ecsB U ABC transporter
NPLLMNCH_00535 5.7e-135 ecsA V ABC transporter, ATP-binding protein
NPLLMNCH_00536 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
NPLLMNCH_00537 3.9e-25
NPLLMNCH_00538 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
NPLLMNCH_00539 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
NPLLMNCH_00540 1.1e-265
NPLLMNCH_00541 2.4e-51 S Domain of unknown function DUF1829
NPLLMNCH_00542 2.9e-23
NPLLMNCH_00543 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPLLMNCH_00544 0.0 L AAA domain
NPLLMNCH_00545 1e-226 yhaO L Ser Thr phosphatase family protein
NPLLMNCH_00546 7.2e-56 yheA S Belongs to the UPF0342 family
NPLLMNCH_00547 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
NPLLMNCH_00548 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPLLMNCH_00549 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
NPLLMNCH_00550 7.5e-103 G Phosphoglycerate mutase family
NPLLMNCH_00551 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
NPLLMNCH_00553 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
NPLLMNCH_00554 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
NPLLMNCH_00555 5.6e-179 S PFAM Archaeal ATPase
NPLLMNCH_00556 2.4e-73 S cog cog1373
NPLLMNCH_00557 2.9e-69 cobB K SIR2 family
NPLLMNCH_00558 2.4e-128 S cog cog1373
NPLLMNCH_00559 1.4e-109 yniG EGP Major facilitator Superfamily
NPLLMNCH_00560 5.4e-237 L transposase, IS605 OrfB family
NPLLMNCH_00561 3.8e-75 yniG EGP Major facilitator Superfamily
NPLLMNCH_00562 4.9e-35
NPLLMNCH_00565 1.3e-42
NPLLMNCH_00566 1.9e-75 M LysM domain
NPLLMNCH_00567 1e-20 S Enterocin A Immunity
NPLLMNCH_00569 5.7e-43 2.4.1.33 V HlyD family secretion protein
NPLLMNCH_00570 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPLLMNCH_00571 2.9e-79 K LytTr DNA-binding domain
NPLLMNCH_00572 2.1e-78 2.7.13.3 T GHKL domain
NPLLMNCH_00574 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
NPLLMNCH_00575 7.7e-26
NPLLMNCH_00576 5.7e-84 S PFAM Archaeal ATPase
NPLLMNCH_00577 2.2e-85 S PFAM Archaeal ATPase
NPLLMNCH_00578 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
NPLLMNCH_00579 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
NPLLMNCH_00580 6.7e-98 M ErfK YbiS YcfS YnhG
NPLLMNCH_00581 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NPLLMNCH_00582 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
NPLLMNCH_00584 4.7e-46 pspC KT PspC domain
NPLLMNCH_00585 3.3e-237 L COG2963 Transposase and inactivated derivatives
NPLLMNCH_00586 1.1e-282 phoR 2.7.13.3 T Histidine kinase
NPLLMNCH_00587 4.3e-121 T Transcriptional regulatory protein, C terminal
NPLLMNCH_00588 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
NPLLMNCH_00589 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPLLMNCH_00590 1.2e-152 pstA P Phosphate transport system permease protein PstA
NPLLMNCH_00591 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
NPLLMNCH_00592 4.2e-145 pstS P Phosphate
NPLLMNCH_00593 1.3e-30
NPLLMNCH_00594 6.3e-192 oppA E ABC transporter, substratebinding protein
NPLLMNCH_00595 4.7e-275 ytgP S Polysaccharide biosynthesis protein
NPLLMNCH_00596 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPLLMNCH_00597 1.1e-121 3.6.1.27 I Acid phosphatase homologues
NPLLMNCH_00598 2.8e-168 K LysR substrate binding domain
NPLLMNCH_00599 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPLLMNCH_00600 6.2e-43 1.3.5.4 C FAD binding domain
NPLLMNCH_00601 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
NPLLMNCH_00602 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
NPLLMNCH_00603 5.5e-178 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
NPLLMNCH_00604 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
NPLLMNCH_00605 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NPLLMNCH_00606 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
NPLLMNCH_00607 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
NPLLMNCH_00608 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
NPLLMNCH_00609 1.1e-129 ybbH_2 K rpiR family
NPLLMNCH_00610 3.4e-195 S Bacterial protein of unknown function (DUF871)
NPLLMNCH_00611 4.1e-214 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPLLMNCH_00612 1.8e-119 S Putative esterase
NPLLMNCH_00613 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
NPLLMNCH_00614 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
NPLLMNCH_00616 8.5e-260 qacA EGP Major facilitator Superfamily
NPLLMNCH_00617 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NPLLMNCH_00620 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
NPLLMNCH_00623 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
NPLLMNCH_00624 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
NPLLMNCH_00625 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
NPLLMNCH_00626 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
NPLLMNCH_00627 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NPLLMNCH_00628 7.5e-100 J Acetyltransferase (GNAT) domain
NPLLMNCH_00629 1.4e-110 yjbF S SNARE associated Golgi protein
NPLLMNCH_00630 6e-151 I alpha/beta hydrolase fold
NPLLMNCH_00631 1.4e-156 hipB K Helix-turn-helix
NPLLMNCH_00632 1.4e-15 S cog cog1373
NPLLMNCH_00633 1e-30 S cog cog1373
NPLLMNCH_00634 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
NPLLMNCH_00635 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
NPLLMNCH_00636 6.1e-227 L COG3547 Transposase and inactivated derivatives
NPLLMNCH_00637 1.8e-163
NPLLMNCH_00638 7.8e-26 K Acetyltransferase (GNAT) domain
NPLLMNCH_00640 0.0 ydgH S MMPL family
NPLLMNCH_00641 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
NPLLMNCH_00642 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
NPLLMNCH_00643 1.8e-154 corA P CorA-like Mg2+ transporter protein
NPLLMNCH_00644 6.7e-240 G Bacterial extracellular solute-binding protein
NPLLMNCH_00645 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
NPLLMNCH_00646 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
NPLLMNCH_00647 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
NPLLMNCH_00648 1.9e-203 malK P ATPases associated with a variety of cellular activities
NPLLMNCH_00649 1.3e-281 pipD E Dipeptidase
NPLLMNCH_00650 1.9e-158 endA F DNA RNA non-specific endonuclease
NPLLMNCH_00651 8.8e-181 dnaQ 2.7.7.7 L EXOIII
NPLLMNCH_00652 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NPLLMNCH_00653 3e-116 yviA S Protein of unknown function (DUF421)
NPLLMNCH_00654 1.1e-56 S Protein of unknown function (DUF3290)
NPLLMNCH_00655 9.3e-86
NPLLMNCH_00656 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPLLMNCH_00657 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
NPLLMNCH_00658 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPLLMNCH_00659 4.4e-140 ypuA S Protein of unknown function (DUF1002)
NPLLMNCH_00660 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
NPLLMNCH_00661 7.3e-126 S Alpha/beta hydrolase family
NPLLMNCH_00663 3.8e-139 pnuC H nicotinamide mononucleotide transporter
NPLLMNCH_00664 4.3e-08
NPLLMNCH_00665 6.6e-56
NPLLMNCH_00666 2.7e-57
NPLLMNCH_00667 1.6e-11
NPLLMNCH_00668 8.1e-126 S PAS domain
NPLLMNCH_00669 6.1e-131 L An automated process has identified a potential problem with this gene model
NPLLMNCH_00670 2.9e-277 V ABC transporter transmembrane region
NPLLMNCH_00671 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
NPLLMNCH_00672 3.1e-130 T Transcriptional regulatory protein, C terminal
NPLLMNCH_00673 5.2e-187 T GHKL domain
NPLLMNCH_00674 3.4e-76 S Peptidase propeptide and YPEB domain
NPLLMNCH_00675 2.5e-72 S Peptidase propeptide and YPEB domain
NPLLMNCH_00676 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NPLLMNCH_00677 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
NPLLMNCH_00678 7e-68 V ABC transporter transmembrane region
NPLLMNCH_00679 9e-161 V ABC transporter transmembrane region
NPLLMNCH_00680 2.3e-309 oppA3 E ABC transporter, substratebinding protein
NPLLMNCH_00681 2.4e-60 ypaA S Protein of unknown function (DUF1304)
NPLLMNCH_00682 2.1e-28 S Peptidase propeptide and YPEB domain
NPLLMNCH_00683 7.1e-237 L transposase, IS605 OrfB family
NPLLMNCH_00684 8.8e-58 S Peptidase propeptide and YPEB domain
NPLLMNCH_00685 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NPLLMNCH_00686 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
NPLLMNCH_00687 7.1e-98 E GDSL-like Lipase/Acylhydrolase
NPLLMNCH_00688 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
NPLLMNCH_00689 1.6e-143 aatB ET ABC transporter substrate-binding protein
NPLLMNCH_00690 1e-105 glnQ 3.6.3.21 E ABC transporter
NPLLMNCH_00691 1.5e-107 glnP P ABC transporter permease
NPLLMNCH_00692 0.0 helD 3.6.4.12 L DNA helicase
NPLLMNCH_00693 5.6e-118 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
NPLLMNCH_00694 1.4e-126 pgm3 G Phosphoglycerate mutase family
NPLLMNCH_00695 1.2e-241 S response to antibiotic
NPLLMNCH_00696 4.9e-125
NPLLMNCH_00697 0.0 3.6.3.8 P P-type ATPase
NPLLMNCH_00698 8.7e-66 2.7.1.191 G PTS system fructose IIA component
NPLLMNCH_00699 4.4e-43
NPLLMNCH_00700 5.9e-09
NPLLMNCH_00701 9.4e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
NPLLMNCH_00702 5.3e-136 glvR K Helix-turn-helix domain, rpiR family
NPLLMNCH_00703 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
NPLLMNCH_00704 5.2e-104
NPLLMNCH_00707 1.9e-117 cps1D M Domain of unknown function (DUF4422)
NPLLMNCH_00708 6.7e-110 rfbP M Bacterial sugar transferase
NPLLMNCH_00709 1.4e-144 ywqE 3.1.3.48 GM PHP domain protein
NPLLMNCH_00710 1.3e-121 ywqD 2.7.10.1 D Capsular exopolysaccharide family
NPLLMNCH_00711 6.5e-146 epsB M biosynthesis protein
NPLLMNCH_00712 1.9e-176 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPLLMNCH_00715 3.8e-216 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NPLLMNCH_00716 3.5e-175 S Cysteine-rich secretory protein family
NPLLMNCH_00717 1.6e-41
NPLLMNCH_00718 2.6e-118 M NlpC/P60 family
NPLLMNCH_00719 1.4e-136 M NlpC P60 family protein
NPLLMNCH_00720 5e-88 M NlpC/P60 family
NPLLMNCH_00721 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
NPLLMNCH_00722 3.9e-42
NPLLMNCH_00723 8.5e-279 S O-antigen ligase like membrane protein
NPLLMNCH_00724 3.3e-112
NPLLMNCH_00725 4.7e-221 tnpB L Putative transposase DNA-binding domain
NPLLMNCH_00726 5.5e-77 nrdI F NrdI Flavodoxin like
NPLLMNCH_00727 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPLLMNCH_00728 2.5e-68
NPLLMNCH_00729 9.1e-112 yvpB S Peptidase_C39 like family
NPLLMNCH_00730 1.1e-83 S Threonine/Serine exporter, ThrE
NPLLMNCH_00731 2.4e-136 thrE S Putative threonine/serine exporter
NPLLMNCH_00732 8.9e-292 S ABC transporter
NPLLMNCH_00733 8.3e-58
NPLLMNCH_00734 5e-72 rimL J Acetyltransferase (GNAT) domain
NPLLMNCH_00735 1.4e-34
NPLLMNCH_00736 1.2e-30
NPLLMNCH_00737 1.8e-111 S Protein of unknown function (DUF554)
NPLLMNCH_00738 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPLLMNCH_00739 5.6e-36
NPLLMNCH_00740 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPLLMNCH_00741 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
NPLLMNCH_00742 2.8e-135
NPLLMNCH_00743 1.3e-258 glnPH2 P ABC transporter permease
NPLLMNCH_00744 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPLLMNCH_00745 6.4e-224 S Cysteine-rich secretory protein family
NPLLMNCH_00746 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
NPLLMNCH_00747 1.4e-112
NPLLMNCH_00748 6.3e-202 yibE S overlaps another CDS with the same product name
NPLLMNCH_00749 4.9e-129 yibF S overlaps another CDS with the same product name
NPLLMNCH_00750 2.5e-144 I alpha/beta hydrolase fold
NPLLMNCH_00751 0.0 G Belongs to the glycosyl hydrolase 31 family
NPLLMNCH_00752 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
NPLLMNCH_00753 0.0 pepF E oligoendopeptidase F
NPLLMNCH_00754 2.9e-31
NPLLMNCH_00755 1.3e-69 doc S Prophage maintenance system killer protein
NPLLMNCH_00758 4.6e-27 S Enterocin A Immunity
NPLLMNCH_00759 1.7e-22 blpT
NPLLMNCH_00761 1.6e-25 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00762 1.2e-11
NPLLMNCH_00763 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
NPLLMNCH_00764 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
NPLLMNCH_00765 2e-264 lctP C L-lactate permease
NPLLMNCH_00766 5e-129 znuB U ABC 3 transport family
NPLLMNCH_00767 1.6e-117 fhuC P ABC transporter
NPLLMNCH_00768 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
NPLLMNCH_00769 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
NPLLMNCH_00770 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
NPLLMNCH_00771 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
NPLLMNCH_00772 1.8e-136 fruR K DeoR C terminal sensor domain
NPLLMNCH_00773 1.8e-218 natB CP ABC-2 family transporter protein
NPLLMNCH_00774 1.1e-164 natA S ABC transporter, ATP-binding protein
NPLLMNCH_00775 1.7e-67
NPLLMNCH_00776 2e-23
NPLLMNCH_00777 8.2e-31 yozG K Transcriptional regulator
NPLLMNCH_00778 3.7e-83
NPLLMNCH_00779 3e-21
NPLLMNCH_00783 2.2e-129 blpT
NPLLMNCH_00784 1.4e-107 M Transport protein ComB
NPLLMNCH_00785 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPLLMNCH_00786 2.1e-121 K LytTr DNA-binding domain
NPLLMNCH_00787 1.6e-132 2.7.13.3 T GHKL domain
NPLLMNCH_00788 1.2e-16
NPLLMNCH_00789 2.1e-255 S Archaea bacterial proteins of unknown function
NPLLMNCH_00790 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
NPLLMNCH_00791 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
NPLLMNCH_00792 1e-24
NPLLMNCH_00793 9.5e-26
NPLLMNCH_00794 2.5e-33
NPLLMNCH_00795 1.4e-53 S Enterocin A Immunity
NPLLMNCH_00796 6.3e-139 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
NPLLMNCH_00797 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NPLLMNCH_00798 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
NPLLMNCH_00799 9.6e-121 K response regulator
NPLLMNCH_00801 0.0 V ABC transporter
NPLLMNCH_00802 4.2e-144 V ABC transporter, ATP-binding protein
NPLLMNCH_00803 1.1e-24 V ABC transporter, ATP-binding protein
NPLLMNCH_00804 3.3e-114 V ABC transporter, ATP-binding protein
NPLLMNCH_00805 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
NPLLMNCH_00806 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
NPLLMNCH_00807 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
NPLLMNCH_00808 8.5e-154 spo0J K Belongs to the ParB family
NPLLMNCH_00809 3.4e-138 soj D Sporulation initiation inhibitor
NPLLMNCH_00810 1.5e-147 noc K Belongs to the ParB family
NPLLMNCH_00811 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
NPLLMNCH_00812 3e-53 cvpA S Colicin V production protein
NPLLMNCH_00814 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
NPLLMNCH_00815 6e-151 3.1.3.48 T Tyrosine phosphatase family
NPLLMNCH_00816 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
NPLLMNCH_00817 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
NPLLMNCH_00818 2.4e-110 K WHG domain
NPLLMNCH_00819 3e-37
NPLLMNCH_00820 1.3e-273 pipD E Dipeptidase
NPLLMNCH_00821 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
NPLLMNCH_00822 3.3e-176 hrtB V ABC transporter permease
NPLLMNCH_00823 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
NPLLMNCH_00824 3.5e-111 G phosphoglycerate mutase
NPLLMNCH_00825 4.1e-141 aroD S Alpha/beta hydrolase family
NPLLMNCH_00826 2.2e-142 S Belongs to the UPF0246 family
NPLLMNCH_00827 9e-121
NPLLMNCH_00828 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
NPLLMNCH_00829 3.9e-186 S Putative peptidoglycan binding domain
NPLLMNCH_00830 4e-16
NPLLMNCH_00831 2.1e-92 liaI S membrane
NPLLMNCH_00832 6.6e-70 XK27_02470 K LytTr DNA-binding domain
NPLLMNCH_00833 1.2e-18 S Sugar efflux transporter for intercellular exchange
NPLLMNCH_00834 1.3e-250 dtpT U amino acid peptide transporter
NPLLMNCH_00835 0.0 pepN 3.4.11.2 E aminopeptidase
NPLLMNCH_00836 2.8e-47 lysM M LysM domain
NPLLMNCH_00837 1.3e-174
NPLLMNCH_00838 1.7e-152 mdtG EGP Major facilitator Superfamily
NPLLMNCH_00839 6.9e-47 mdtG EGP Major facilitator Superfamily
NPLLMNCH_00840 4.6e-88 ymdB S Macro domain protein
NPLLMNCH_00842 4.8e-28
NPLLMNCH_00845 4.3e-67 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00846 3.3e-147 malG P ABC transporter permease
NPLLMNCH_00847 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
NPLLMNCH_00848 1.3e-213 malE G Bacterial extracellular solute-binding protein
NPLLMNCH_00849 6.8e-209 msmX P Belongs to the ABC transporter superfamily
NPLLMNCH_00850 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
NPLLMNCH_00851 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
NPLLMNCH_00852 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
NPLLMNCH_00853 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
NPLLMNCH_00854 9.8e-49 S PAS domain
NPLLMNCH_00855 2e-203 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPLLMNCH_00856 3.1e-178 yvdE K helix_turn _helix lactose operon repressor
NPLLMNCH_00857 6.3e-145 ptp2 3.1.3.48 T Tyrosine phosphatase family
NPLLMNCH_00858 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NPLLMNCH_00859 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
NPLLMNCH_00860 1.7e-184 G Transmembrane secretion effector
NPLLMNCH_00861 6.1e-136 V ABC transporter transmembrane region
NPLLMNCH_00862 2.9e-224 L transposase, IS605 OrfB family
NPLLMNCH_00863 1.1e-75 V ABC transporter transmembrane region
NPLLMNCH_00864 6.5e-64 L RelB antitoxin
NPLLMNCH_00865 2.1e-131 cobQ S glutamine amidotransferase
NPLLMNCH_00866 1.8e-81 M NlpC/P60 family
NPLLMNCH_00869 2.6e-155
NPLLMNCH_00870 7.8e-38
NPLLMNCH_00871 2e-32
NPLLMNCH_00872 6.2e-163 EG EamA-like transporter family
NPLLMNCH_00873 5e-165 EG EamA-like transporter family
NPLLMNCH_00874 3.6e-139 yicL EG EamA-like transporter family
NPLLMNCH_00875 4.3e-107
NPLLMNCH_00876 1.1e-110
NPLLMNCH_00877 5.8e-186 XK27_05540 S DUF218 domain
NPLLMNCH_00878 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
NPLLMNCH_00879 4.7e-85
NPLLMNCH_00880 3.9e-57
NPLLMNCH_00881 4.7e-25 S Protein conserved in bacteria
NPLLMNCH_00882 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
NPLLMNCH_00883 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
NPLLMNCH_00884 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NPLLMNCH_00885 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NPLLMNCH_00886 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPLLMNCH_00889 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
NPLLMNCH_00890 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
NPLLMNCH_00891 1.8e-230 steT_1 E amino acid
NPLLMNCH_00892 2.2e-139 puuD S peptidase C26
NPLLMNCH_00894 2.4e-172 V HNH endonuclease
NPLLMNCH_00895 6.4e-135 S PFAM Archaeal ATPase
NPLLMNCH_00896 9.2e-248 yifK E Amino acid permease
NPLLMNCH_00897 9.7e-234 cycA E Amino acid permease
NPLLMNCH_00898 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPLLMNCH_00899 0.0 clpE O AAA domain (Cdc48 subfamily)
NPLLMNCH_00900 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
NPLLMNCH_00901 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_00902 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
NPLLMNCH_00903 0.0 XK27_06780 V ABC transporter permease
NPLLMNCH_00904 1.9e-36
NPLLMNCH_00905 7.9e-291 ytgP S Polysaccharide biosynthesis protein
NPLLMNCH_00906 2.7e-137 lysA2 M Glycosyl hydrolases family 25
NPLLMNCH_00907 2.3e-133 S Protein of unknown function (DUF975)
NPLLMNCH_00908 7.6e-177 pbpX2 V Beta-lactamase
NPLLMNCH_00909 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
NPLLMNCH_00910 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPLLMNCH_00911 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
NPLLMNCH_00912 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
NPLLMNCH_00913 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
NPLLMNCH_00914 4.1e-44
NPLLMNCH_00915 1e-207 ywhK S Membrane
NPLLMNCH_00916 1.5e-80 ykuL S (CBS) domain
NPLLMNCH_00917 0.0 cadA P P-type ATPase
NPLLMNCH_00918 2.8e-205 napA P Sodium/hydrogen exchanger family
NPLLMNCH_00919 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
NPLLMNCH_00920 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
NPLLMNCH_00921 4.1e-276 V ABC transporter transmembrane region
NPLLMNCH_00922 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00923 5.4e-51
NPLLMNCH_00924 4.2e-154 EGP Major facilitator Superfamily
NPLLMNCH_00925 3e-111 ropB K Transcriptional regulator
NPLLMNCH_00926 2.7e-120 S CAAX protease self-immunity
NPLLMNCH_00927 1.6e-194 S DUF218 domain
NPLLMNCH_00928 0.0 macB_3 V ABC transporter, ATP-binding protein
NPLLMNCH_00929 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NPLLMNCH_00930 2.8e-100 S ECF transporter, substrate-specific component
NPLLMNCH_00931 3.9e-201 tcsA S ABC transporter substrate-binding protein PnrA-like
NPLLMNCH_00932 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
NPLLMNCH_00933 1.3e-282 xylG 3.6.3.17 S ABC transporter
NPLLMNCH_00934 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
NPLLMNCH_00935 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
NPLLMNCH_00936 3.7e-159 yeaE S Aldo/keto reductase family
NPLLMNCH_00937 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
NPLLMNCH_00938 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPLLMNCH_00939 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
NPLLMNCH_00940 9.4e-72
NPLLMNCH_00941 4.5e-112 cof S haloacid dehalogenase-like hydrolase
NPLLMNCH_00942 8.2e-230 pbuG S permease
NPLLMNCH_00943 2.1e-76 S ABC-2 family transporter protein
NPLLMNCH_00944 4.7e-60 S ABC-2 family transporter protein
NPLLMNCH_00945 2.4e-92 V ABC transporter, ATP-binding protein
NPLLMNCH_00946 3.3e-37
NPLLMNCH_00947 2.5e-119 K helix_turn_helix, mercury resistance
NPLLMNCH_00948 7.5e-231 pbuG S permease
NPLLMNCH_00949 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
NPLLMNCH_00950 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_00951 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
NPLLMNCH_00953 1.9e-83 K Transcriptional regulator
NPLLMNCH_00954 6.1e-61 K Transcriptional regulator
NPLLMNCH_00955 2e-225 S cog cog1373
NPLLMNCH_00956 9.7e-146 S haloacid dehalogenase-like hydrolase
NPLLMNCH_00957 2.5e-226 pbuG S permease
NPLLMNCH_00958 1.4e-37 S Putative adhesin
NPLLMNCH_00959 2.6e-151 V ABC transporter transmembrane region
NPLLMNCH_00960 4.6e-138
NPLLMNCH_00961 1.8e-31
NPLLMNCH_00964 2.4e-36
NPLLMNCH_00965 9.2e-57 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPLLMNCH_00966 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
NPLLMNCH_00967 0.0 copA 3.6.3.54 P P-type ATPase
NPLLMNCH_00968 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
NPLLMNCH_00969 1.2e-105
NPLLMNCH_00970 7e-248 EGP Sugar (and other) transporter
NPLLMNCH_00971 1.2e-18
NPLLMNCH_00972 2.8e-210
NPLLMNCH_00973 3.5e-136 S SLAP domain
NPLLMNCH_00974 2.8e-117 S SLAP domain
NPLLMNCH_00975 1.1e-106 S Bacteriocin helveticin-J
NPLLMNCH_00976 1.2e-44
NPLLMNCH_00977 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_00978 4e-32 E Zn peptidase
NPLLMNCH_00979 3.9e-287 clcA P chloride
NPLLMNCH_00980 3.3e-127 L PFAM transposase IS116 IS110 IS902
NPLLMNCH_00981 4.7e-13 S Phage Terminase
NPLLMNCH_00983 9.1e-135 S Phage portal protein
NPLLMNCH_00984 5.5e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
NPLLMNCH_00985 2e-55 S Phage capsid family
NPLLMNCH_00986 5.2e-17 S Phage gp6-like head-tail connector protein
NPLLMNCH_00988 8.6e-14 S Bacteriophage HK97-gp10, putative tail-component
NPLLMNCH_00990 3.1e-13 S Pfam:Phage_TTP_1
NPLLMNCH_00993 2e-127 M Phage tail tape measure protein TP901
NPLLMNCH_00994 4.5e-34 S phage tail
NPLLMNCH_00995 6e-136 S Phage minor structural protein
NPLLMNCH_00999 8.2e-85 scrR K Periplasmic binding protein domain
NPLLMNCH_01000 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
NPLLMNCH_01001 5.4e-13
NPLLMNCH_01002 5.2e-08
NPLLMNCH_01003 3e-89 ntd 2.4.2.6 F Nucleoside
NPLLMNCH_01004 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPLLMNCH_01005 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
NPLLMNCH_01006 2.2e-82 uspA T universal stress protein
NPLLMNCH_01008 1.2e-161 phnD P Phosphonate ABC transporter
NPLLMNCH_01009 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NPLLMNCH_01010 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPLLMNCH_01011 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
NPLLMNCH_01012 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
NPLLMNCH_01013 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
NPLLMNCH_01014 1.6e-105 tag 3.2.2.20 L glycosylase
NPLLMNCH_01015 3.9e-84
NPLLMNCH_01016 1.7e-273 S Calcineurin-like phosphoesterase
NPLLMNCH_01017 0.0 asnB 6.3.5.4 E Asparagine synthase
NPLLMNCH_01018 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
NPLLMNCH_01019 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
NPLLMNCH_01020 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NPLLMNCH_01021 2.1e-103 S Iron-sulfur cluster assembly protein
NPLLMNCH_01022 1.5e-230 XK27_04775 S PAS domain
NPLLMNCH_01023 2.3e-210 yttB EGP Major facilitator Superfamily
NPLLMNCH_01024 0.0 pepO 3.4.24.71 O Peptidase family M13
NPLLMNCH_01025 0.0 kup P Transport of potassium into the cell
NPLLMNCH_01026 7.3e-74
NPLLMNCH_01027 2.1e-45 S PFAM Archaeal ATPase
NPLLMNCH_01029 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_01030 5.9e-45
NPLLMNCH_01032 5.5e-30
NPLLMNCH_01033 4.3e-40 S Protein of unknown function (DUF2922)
NPLLMNCH_01034 4e-131 S SLAP domain
NPLLMNCH_01036 5.3e-41
NPLLMNCH_01037 1.2e-77 K DNA-templated transcription, initiation
NPLLMNCH_01038 1.1e-25
NPLLMNCH_01039 4.3e-145 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPLLMNCH_01041 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPLLMNCH_01042 2.9e-105 S SLAP domain
NPLLMNCH_01044 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
NPLLMNCH_01045 2.5e-179 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
NPLLMNCH_01046 0.0 yjbQ P TrkA C-terminal domain protein
NPLLMNCH_01047 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NPLLMNCH_01048 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
NPLLMNCH_01049 2.1e-130
NPLLMNCH_01050 2.1e-116
NPLLMNCH_01051 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPLLMNCH_01052 1.4e-98 G Aldose 1-epimerase
NPLLMNCH_01053 1e-201 brpA K Cell envelope-like function transcriptional attenuator common domain protein
NPLLMNCH_01054 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPLLMNCH_01055 0.0 XK27_08315 M Sulfatase
NPLLMNCH_01056 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
NPLLMNCH_01057 5.7e-69 rplI J Binds to the 23S rRNA
NPLLMNCH_01058 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
NPLLMNCH_01059 8.4e-265 S Fibronectin type III domain
NPLLMNCH_01060 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NPLLMNCH_01061 3.4e-53
NPLLMNCH_01063 4.6e-257 pepC 3.4.22.40 E aminopeptidase
NPLLMNCH_01064 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPLLMNCH_01065 5e-301 oppA E ABC transporter, substratebinding protein
NPLLMNCH_01066 1.6e-310 oppA E ABC transporter, substratebinding protein
NPLLMNCH_01067 8.3e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
NPLLMNCH_01068 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPLLMNCH_01069 8.9e-187 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
NPLLMNCH_01070 2.3e-198 oppD P Belongs to the ABC transporter superfamily
NPLLMNCH_01071 1.9e-175 oppF P Belongs to the ABC transporter superfamily
NPLLMNCH_01072 5.2e-256 pepC 3.4.22.40 E aminopeptidase
NPLLMNCH_01073 2.9e-67 hsp O Belongs to the small heat shock protein (HSP20) family
NPLLMNCH_01074 7.5e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
NPLLMNCH_01075 6e-112
NPLLMNCH_01077 1.7e-110 E Belongs to the SOS response-associated peptidase family
NPLLMNCH_01078 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPLLMNCH_01079 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
NPLLMNCH_01080 2e-103 S TPM domain
NPLLMNCH_01081 2.4e-132 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPLLMNCH_01082 2.5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPLLMNCH_01083 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NPLLMNCH_01084 1e-147 tatD L hydrolase, TatD family
NPLLMNCH_01085 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NPLLMNCH_01086 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
NPLLMNCH_01087 4.5e-39 veg S Biofilm formation stimulator VEG
NPLLMNCH_01088 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
NPLLMNCH_01089 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NPLLMNCH_01090 5.3e-80
NPLLMNCH_01091 7.8e-292 S SLAP domain
NPLLMNCH_01092 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NPLLMNCH_01093 4.2e-172 2.7.1.2 GK ROK family
NPLLMNCH_01094 5.6e-43
NPLLMNCH_01095 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
NPLLMNCH_01096 6.9e-69 S Domain of unknown function (DUF1934)
NPLLMNCH_01097 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
NPLLMNCH_01098 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
NPLLMNCH_01099 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NPLLMNCH_01100 1.8e-74 K acetyltransferase
NPLLMNCH_01101 5.7e-285 pipD E Dipeptidase
NPLLMNCH_01102 3.7e-156 msmR K AraC-like ligand binding domain
NPLLMNCH_01103 1.5e-223 pbuX F xanthine permease
NPLLMNCH_01104 9e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
NPLLMNCH_01105 2.4e-43 K Helix-turn-helix
NPLLMNCH_01106 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
NPLLMNCH_01108 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
NPLLMNCH_01109 3.6e-225 3.2.1.18 GH33 M Rib/alpha-like repeat
NPLLMNCH_01110 6.5e-55 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPLLMNCH_01111 4.3e-247 3.2.1.18 GH33 M Rib/alpha-like repeat
NPLLMNCH_01113 1.7e-77 2.5.1.74 H UbiA prenyltransferase family
NPLLMNCH_01114 1e-95
NPLLMNCH_01115 5.2e-65 C NADH flavin oxidoreductase NADH oxidase
NPLLMNCH_01116 1.3e-141 yfeO P Voltage gated chloride channel
NPLLMNCH_01117 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
NPLLMNCH_01118 1.4e-51
NPLLMNCH_01119 2.1e-42
NPLLMNCH_01120 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NPLLMNCH_01121 2.8e-296 ybeC E amino acid
NPLLMNCH_01122 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
NPLLMNCH_01123 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
NPLLMNCH_01124 2.5e-39 rpmE2 J Ribosomal protein L31
NPLLMNCH_01125 1.2e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
NPLLMNCH_01126 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
NPLLMNCH_01127 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
NPLLMNCH_01128 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NPLLMNCH_01129 3.4e-129 S (CBS) domain
NPLLMNCH_01130 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPLLMNCH_01131 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
NPLLMNCH_01132 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NPLLMNCH_01133 1.6e-33 yabO J S4 domain protein
NPLLMNCH_01134 6.8e-60 divIC D Septum formation initiator
NPLLMNCH_01135 1.8e-62 yabR J S1 RNA binding domain
NPLLMNCH_01136 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
NPLLMNCH_01137 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NPLLMNCH_01138 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NPLLMNCH_01139 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NPLLMNCH_01140 1.1e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
NPLLMNCH_01141 1.4e-83 K FR47-like protein
NPLLMNCH_01142 1.6e-08
NPLLMNCH_01143 1.6e-08
NPLLMNCH_01145 1.3e-81 yebR 1.8.4.14 T GAF domain-containing protein
NPLLMNCH_01146 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
NPLLMNCH_01147 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPLLMNCH_01148 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPLLMNCH_01149 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
NPLLMNCH_01150 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NPLLMNCH_01151 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
NPLLMNCH_01152 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NPLLMNCH_01153 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
NPLLMNCH_01154 9e-113 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NPLLMNCH_01155 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
NPLLMNCH_01156 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
NPLLMNCH_01157 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NPLLMNCH_01158 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NPLLMNCH_01159 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NPLLMNCH_01160 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NPLLMNCH_01161 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NPLLMNCH_01162 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
NPLLMNCH_01163 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NPLLMNCH_01164 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NPLLMNCH_01165 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NPLLMNCH_01166 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NPLLMNCH_01167 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPLLMNCH_01168 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NPLLMNCH_01169 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NPLLMNCH_01170 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NPLLMNCH_01171 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NPLLMNCH_01172 2.3e-24 rpmD J Ribosomal protein L30
NPLLMNCH_01173 1.3e-70 rplO J Binds to the 23S rRNA
NPLLMNCH_01174 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
NPLLMNCH_01175 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
NPLLMNCH_01176 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NPLLMNCH_01177 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
NPLLMNCH_01178 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NPLLMNCH_01179 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NPLLMNCH_01180 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NPLLMNCH_01181 1.4e-60 rplQ J Ribosomal protein L17
NPLLMNCH_01182 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPLLMNCH_01183 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPLLMNCH_01184 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NPLLMNCH_01185 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
NPLLMNCH_01186 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NPLLMNCH_01187 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
NPLLMNCH_01188 3.6e-183 L Phage integrase family
NPLLMNCH_01189 1.1e-46 MA20_28645 3.6.3.29, 3.6.3.41 S ABC transporter
NPLLMNCH_01190 2.8e-65 K LytTr DNA-binding domain
NPLLMNCH_01191 1.2e-49 S Protein of unknown function (DUF3021)
NPLLMNCH_01192 2.4e-104 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
NPLLMNCH_01193 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPLLMNCH_01194 1.1e-133 S membrane transporter protein
NPLLMNCH_01195 2.2e-125 gpmB G Belongs to the phosphoglycerate mutase family
NPLLMNCH_01196 6.6e-162 czcD P cation diffusion facilitator family transporter
NPLLMNCH_01197 1.4e-23
NPLLMNCH_01198 1.7e-125 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NPLLMNCH_01199 2.4e-183 S AAA domain
NPLLMNCH_01200 7.3e-44
NPLLMNCH_01201 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
NPLLMNCH_01202 4.1e-52
NPLLMNCH_01203 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
NPLLMNCH_01204 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NPLLMNCH_01205 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NPLLMNCH_01206 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
NPLLMNCH_01207 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
NPLLMNCH_01208 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NPLLMNCH_01209 1.2e-94 sigH K Belongs to the sigma-70 factor family
NPLLMNCH_01210 1.7e-34
NPLLMNCH_01211 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
NPLLMNCH_01212 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NPLLMNCH_01213 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
NPLLMNCH_01214 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
NPLLMNCH_01215 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NPLLMNCH_01216 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
NPLLMNCH_01217 2.8e-157 pstS P Phosphate
NPLLMNCH_01218 2.6e-162 pstC P probably responsible for the translocation of the substrate across the membrane
NPLLMNCH_01219 1.2e-57 L Transposase
NPLLMNCH_01220 2.5e-15
NPLLMNCH_01222 4.9e-85 L Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
NPLLMNCH_01223 5.7e-154 pstA P Phosphate transport system permease protein PstA
NPLLMNCH_01224 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPLLMNCH_01225 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
NPLLMNCH_01226 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
NPLLMNCH_01227 2.8e-90 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01228 1.5e-11 GT2,GT4 M family 8
NPLLMNCH_01229 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NPLLMNCH_01230 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
NPLLMNCH_01231 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
NPLLMNCH_01232 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
NPLLMNCH_01233 9e-26
NPLLMNCH_01234 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
NPLLMNCH_01235 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NPLLMNCH_01236 5.7e-106 2.4.1.58 GT8 M family 8
NPLLMNCH_01237 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
NPLLMNCH_01238 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NPLLMNCH_01239 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NPLLMNCH_01240 1.1e-34 S Protein of unknown function (DUF2508)
NPLLMNCH_01241 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NPLLMNCH_01242 8.9e-53 yaaQ S Cyclic-di-AMP receptor
NPLLMNCH_01243 1.5e-155 holB 2.7.7.7 L DNA polymerase III
NPLLMNCH_01244 1.8e-59 yabA L Involved in initiation control of chromosome replication
NPLLMNCH_01245 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NPLLMNCH_01246 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
NPLLMNCH_01247 2.2e-85 S ECF transporter, substrate-specific component
NPLLMNCH_01248 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
NPLLMNCH_01249 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
NPLLMNCH_01250 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NPLLMNCH_01251 1.9e-245 L Transposase IS66 family
NPLLMNCH_01252 8.7e-34 S Transposase C of IS166 homeodomain
NPLLMNCH_01253 9.3e-64 L PFAM IS66 Orf2 family protein
NPLLMNCH_01254 7.7e-22
NPLLMNCH_01255 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPLLMNCH_01256 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
NPLLMNCH_01257 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
NPLLMNCH_01258 0.0 uup S ABC transporter, ATP-binding protein
NPLLMNCH_01259 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NPLLMNCH_01262 4.2e-56 S Phage terminase, small subunit
NPLLMNCH_01263 9.1e-43 S HNH endonuclease
NPLLMNCH_01264 3.4e-18
NPLLMNCH_01266 3.3e-37 S VRR_NUC
NPLLMNCH_01274 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
NPLLMNCH_01275 5.3e-45 yitW S Iron-sulfur cluster assembly protein
NPLLMNCH_01276 2e-266 sufB O assembly protein SufB
NPLLMNCH_01277 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
NPLLMNCH_01278 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPLLMNCH_01279 3.5e-174 sufD O FeS assembly protein SufD
NPLLMNCH_01280 2.8e-140 sufC O FeS assembly ATPase SufC
NPLLMNCH_01281 1.5e-234 L Transposase DDE domain
NPLLMNCH_01282 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
NPLLMNCH_01283 5.2e-170 degV S DegV family
NPLLMNCH_01284 1.1e-135 V ABC transporter transmembrane region
NPLLMNCH_01285 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
NPLLMNCH_01287 1.4e-16
NPLLMNCH_01288 2e-192 L COG2963 Transposase and inactivated derivatives
NPLLMNCH_01289 1.5e-76 L Transposase
NPLLMNCH_01292 1.2e-152 L Putative transposase DNA-binding domain
NPLLMNCH_01293 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NPLLMNCH_01294 4.1e-93 L Transposase and inactivated derivatives, IS30 family
NPLLMNCH_01295 1.1e-183 scrR K helix_turn _helix lactose operon repressor
NPLLMNCH_01296 3.7e-295 scrB 3.2.1.26 GH32 G invertase
NPLLMNCH_01297 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
NPLLMNCH_01298 2.3e-181 M CHAP domain
NPLLMNCH_01299 3.5e-75
NPLLMNCH_01300 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NPLLMNCH_01301 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
NPLLMNCH_01302 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NPLLMNCH_01303 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NPLLMNCH_01304 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
NPLLMNCH_01305 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
NPLLMNCH_01306 9.6e-41 yajC U Preprotein translocase
NPLLMNCH_01307 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
NPLLMNCH_01308 1.7e-215 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NPLLMNCH_01309 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
NPLLMNCH_01310 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
NPLLMNCH_01311 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NPLLMNCH_01312 2e-42 yrzL S Belongs to the UPF0297 family
NPLLMNCH_01313 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NPLLMNCH_01314 1.1e-50 yrzB S Belongs to the UPF0473 family
NPLLMNCH_01315 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPLLMNCH_01316 3.5e-54 trxA O Belongs to the thioredoxin family
NPLLMNCH_01317 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
NPLLMNCH_01318 1.1e-71 yslB S Protein of unknown function (DUF2507)
NPLLMNCH_01319 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
NPLLMNCH_01320 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NPLLMNCH_01321 7.7e-30 ropB K Helix-turn-helix domain
NPLLMNCH_01322 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NPLLMNCH_01323 5.4e-113
NPLLMNCH_01324 1.7e-139
NPLLMNCH_01325 6.9e-100 V ATPases associated with a variety of cellular activities
NPLLMNCH_01326 3.7e-146 ykuT M mechanosensitive ion channel
NPLLMNCH_01327 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
NPLLMNCH_01328 1.3e-36
NPLLMNCH_01329 8.4e-142 L Transposase
NPLLMNCH_01330 2.2e-22
NPLLMNCH_01331 3.3e-140 repB EP Plasmid replication protein
NPLLMNCH_01332 1e-78 S helix_turn_helix, Deoxyribose operon repressor
NPLLMNCH_01333 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
NPLLMNCH_01334 3.2e-181 ccpA K catabolite control protein A
NPLLMNCH_01335 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPLLMNCH_01336 4.3e-55
NPLLMNCH_01337 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
NPLLMNCH_01338 2.1e-92 yutD S Protein of unknown function (DUF1027)
NPLLMNCH_01339 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
NPLLMNCH_01340 3.7e-100 S Protein of unknown function (DUF1461)
NPLLMNCH_01341 6.8e-116 dedA S SNARE-like domain protein
NPLLMNCH_01342 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
NPLLMNCH_01343 2.1e-45 S O-antigen ligase like membrane protein
NPLLMNCH_01344 5.1e-82 glfT1 1.1.1.133 S Glycosyltransferase, group 2 family protein
NPLLMNCH_01345 5.3e-76 M Glycosyltransferase, group 1 family protein
NPLLMNCH_01346 1.7e-42 M Glycosyl transferase family 2
NPLLMNCH_01347 2.2e-54 oppA E ABC transporter substrate-binding protein
NPLLMNCH_01348 1.3e-149 oppA E ABC transporter substrate-binding protein
NPLLMNCH_01376 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
NPLLMNCH_01377 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
NPLLMNCH_01378 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NPLLMNCH_01379 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPLLMNCH_01380 1.7e-29 secG U Preprotein translocase
NPLLMNCH_01381 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
NPLLMNCH_01382 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
NPLLMNCH_01383 1.1e-95 C aldehyde oxidase and xanthine dehydrogenase, a b hammerhead
NPLLMNCH_01384 1.6e-45 nanT EGP Major facilitator Superfamily
NPLLMNCH_01385 1.2e-70 MA20_43810 Q FtsX-like permease family
NPLLMNCH_01387 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
NPLLMNCH_01388 1.7e-129 manY G PTS system
NPLLMNCH_01389 1e-173 manN G system, mannose fructose sorbose family IID component
NPLLMNCH_01390 1.1e-62 manO S Domain of unknown function (DUF956)
NPLLMNCH_01391 3.3e-158 K Transcriptional regulator
NPLLMNCH_01392 1.3e-85 maa S transferase hexapeptide repeat
NPLLMNCH_01393 1.7e-241 cycA E Amino acid permease
NPLLMNCH_01394 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPLLMNCH_01395 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
NPLLMNCH_01396 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
NPLLMNCH_01397 0.0 mtlR K Mga helix-turn-helix domain
NPLLMNCH_01398 0.0 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
NPLLMNCH_01399 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_01400 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
NPLLMNCH_01401 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPLLMNCH_01402 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
NPLLMNCH_01403 2.1e-32
NPLLMNCH_01404 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
NPLLMNCH_01405 2.3e-156 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01406 3.9e-298 V ABC transporter transmembrane region
NPLLMNCH_01407 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
NPLLMNCH_01408 1.7e-193 S TerB-C domain
NPLLMNCH_01409 4.9e-161 L PFAM transposase, IS4 family protein
NPLLMNCH_01410 2.9e-174 L Bifunctional protein
NPLLMNCH_01411 1.9e-19 L Replication initiation factor
NPLLMNCH_01412 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPLLMNCH_01413 9.3e-74 nrdI F NrdI Flavodoxin like
NPLLMNCH_01414 3.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NPLLMNCH_01415 2.6e-138 S TerB-C domain
NPLLMNCH_01416 1.4e-245 P P-loop Domain of unknown function (DUF2791)
NPLLMNCH_01417 0.0 lhr L DEAD DEAH box helicase
NPLLMNCH_01418 1.4e-60
NPLLMNCH_01419 4.3e-228 amtB P ammonium transporter
NPLLMNCH_01420 4.4e-135 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
NPLLMNCH_01422 6.6e-61 psiE S Phosphate-starvation-inducible E
NPLLMNCH_01423 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
NPLLMNCH_01424 2.2e-60 S Iron-sulphur cluster biosynthesis
NPLLMNCH_01426 2.3e-30
NPLLMNCH_01427 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
NPLLMNCH_01428 6.2e-12
NPLLMNCH_01429 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_01430 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_01431 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_01432 5.8e-78 M LysM domain protein
NPLLMNCH_01433 4.7e-159 D nuclear chromosome segregation
NPLLMNCH_01434 1.2e-105 G Phosphoglycerate mutase family
NPLLMNCH_01435 2.6e-89 G Histidine phosphatase superfamily (branch 1)
NPLLMNCH_01436 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPLLMNCH_01437 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
NPLLMNCH_01439 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
NPLLMNCH_01441 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
NPLLMNCH_01442 2.7e-185 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
NPLLMNCH_01443 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
NPLLMNCH_01444 4.4e-144 K SIS domain
NPLLMNCH_01445 1.1e-227 slpX S SLAP domain
NPLLMNCH_01446 1.3e-22 3.6.4.12 S transposase or invertase
NPLLMNCH_01447 2.3e-11
NPLLMNCH_01448 4.9e-241 npr 1.11.1.1 C NADH oxidase
NPLLMNCH_01451 1.6e-299 oppA2 E ABC transporter, substratebinding protein
NPLLMNCH_01452 2.5e-179
NPLLMNCH_01453 4.6e-123 gntR1 K UTRA
NPLLMNCH_01454 1.5e-70 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
NPLLMNCH_01455 8.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
NPLLMNCH_01456 5e-204 csaB M Glycosyl transferases group 1
NPLLMNCH_01457 2e-285 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NPLLMNCH_01458 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
NPLLMNCH_01459 1.4e-204 tnpB L Putative transposase DNA-binding domain
NPLLMNCH_01460 0.0 pacL 3.6.3.8 P P-type ATPase
NPLLMNCH_01461 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
NPLLMNCH_01462 6e-258 epsU S Polysaccharide biosynthesis protein
NPLLMNCH_01463 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
NPLLMNCH_01464 4.1e-83 ydcK S Belongs to the SprT family
NPLLMNCH_01466 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
NPLLMNCH_01467 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
NPLLMNCH_01468 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NPLLMNCH_01469 5.8e-203 camS S sex pheromone
NPLLMNCH_01470 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPLLMNCH_01471 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
NPLLMNCH_01472 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NPLLMNCH_01473 2.7e-171 yegS 2.7.1.107 G Lipid kinase
NPLLMNCH_01474 4.3e-108 ybhL S Belongs to the BI1 family
NPLLMNCH_01475 2.6e-57
NPLLMNCH_01476 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
NPLLMNCH_01477 2.8e-244 nhaC C Na H antiporter NhaC
NPLLMNCH_01478 6.3e-201 pbpX V Beta-lactamase
NPLLMNCH_01479 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPLLMNCH_01480 1.1e-94 MA20_25245 K Acetyltransferase (GNAT) domain
NPLLMNCH_01485 1.9e-259 emrY EGP Major facilitator Superfamily
NPLLMNCH_01486 2e-91 yxdD K Bacterial regulatory proteins, tetR family
NPLLMNCH_01487 0.0 4.2.1.53 S Myosin-crossreactive antigen
NPLLMNCH_01488 5.5e-148 S cog cog1373
NPLLMNCH_01489 1.1e-68 sagB C Nitroreductase family
NPLLMNCH_01490 3.4e-09
NPLLMNCH_01492 1.2e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
NPLLMNCH_01493 2.5e-38 L Protein of unknown function (DUF3991)
NPLLMNCH_01494 1e-18 L Psort location Cytoplasmic, score
NPLLMNCH_01495 2.5e-47 L Psort location Cytoplasmic, score
NPLLMNCH_01496 3.4e-24 relB L Addiction module antitoxin, RelB DinJ family
NPLLMNCH_01497 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_01499 3.4e-134 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
NPLLMNCH_01501 1.1e-23 S CAAX protease self-immunity
NPLLMNCH_01503 4.1e-34
NPLLMNCH_01504 1e-66 doc S Fic/DOC family
NPLLMNCH_01506 9.4e-51 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01507 7.9e-16 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01509 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
NPLLMNCH_01510 9.7e-205 gatC G PTS system sugar-specific permease component
NPLLMNCH_01511 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
NPLLMNCH_01512 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPLLMNCH_01513 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NPLLMNCH_01514 2.4e-99 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01515 4.1e-17 V N-6 DNA Methylase
NPLLMNCH_01516 8.8e-41 clcA P chloride
NPLLMNCH_01517 1.6e-60 clcA P chloride
NPLLMNCH_01518 4.7e-26 K FCD
NPLLMNCH_01519 1.4e-09 K FCD
NPLLMNCH_01520 3e-270 L Transposase DDE domain
NPLLMNCH_01521 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
NPLLMNCH_01522 2e-157 S reductase
NPLLMNCH_01523 9.3e-35
NPLLMNCH_01524 8.9e-17 G Bacterial extracellular solute-binding protein, family 7
NPLLMNCH_01525 5e-78 K Putative DNA-binding domain
NPLLMNCH_01526 3e-130 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01527 9.6e-184 L DDE superfamily endonuclease
NPLLMNCH_01528 3.7e-27 L Transposase
NPLLMNCH_01529 6.8e-226 I Protein of unknown function (DUF2974)
NPLLMNCH_01530 1.9e-116 yhiD S MgtC family
NPLLMNCH_01532 1.4e-18 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01533 6.9e-64
NPLLMNCH_01534 2.6e-84
NPLLMNCH_01535 1.4e-134 D Ftsk spoiiie family protein
NPLLMNCH_01536 7.6e-124 S Replication initiation factor
NPLLMNCH_01537 1.4e-140 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01538 1.6e-10 T Adenylyl- / guanylyl cyclase, catalytic domain
NPLLMNCH_01539 1.9e-22 K Putative DNA-binding domain
NPLLMNCH_01540 7.6e-239 pyrP F Permease
NPLLMNCH_01541 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
NPLLMNCH_01542 9.2e-262 emrY EGP Major facilitator Superfamily
NPLLMNCH_01543 8e-21 MA20_17180 K LysR substrate binding domain
NPLLMNCH_01544 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
NPLLMNCH_01545 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
NPLLMNCH_01546 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
NPLLMNCH_01547 1.9e-19
NPLLMNCH_01548 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NPLLMNCH_01549 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
NPLLMNCH_01550 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPLLMNCH_01551 8.3e-40 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NPLLMNCH_01552 4e-40 S CRISPR-associated protein (Cas_Csn2)
NPLLMNCH_01555 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
NPLLMNCH_01556 5.1e-155 mdtG EGP Major facilitator Superfamily
NPLLMNCH_01558 2.6e-29 kynU 3.7.1.3 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NPLLMNCH_01559 3.8e-15 S Domain of Unknown Function with PDB structure (DUF3850)
NPLLMNCH_01561 2.9e-12
NPLLMNCH_01562 2e-18 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
NPLLMNCH_01564 3e-112 L PFAM transposase IS116 IS110 IS902
NPLLMNCH_01565 4.7e-182 pepA E M42 glutamyl aminopeptidase
NPLLMNCH_01566 2.2e-311 ybiT S ABC transporter, ATP-binding protein
NPLLMNCH_01567 5.9e-174 S Aldo keto reductase
NPLLMNCH_01568 2.7e-138
NPLLMNCH_01569 2.8e-202 steT E amino acid
NPLLMNCH_01570 2.4e-26 steT E amino acid
NPLLMNCH_01571 8.6e-243 steT E amino acid
NPLLMNCH_01572 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
NPLLMNCH_01573 1.9e-147 glnH ET ABC transporter
NPLLMNCH_01574 1.4e-80 K Transcriptional regulator, MarR family
NPLLMNCH_01575 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
NPLLMNCH_01576 0.0 V ABC transporter transmembrane region
NPLLMNCH_01577 1.6e-100 S ABC-type cobalt transport system, permease component
NPLLMNCH_01578 1e-246 G MFS/sugar transport protein
NPLLMNCH_01579 1e-44 udk 2.7.1.48 F Zeta toxin
NPLLMNCH_01580 3.8e-46 udk 2.7.1.48 F Zeta toxin
NPLLMNCH_01581 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
NPLLMNCH_01582 1.2e-146 glnH ET ABC transporter substrate-binding protein
NPLLMNCH_01583 3.7e-90 gluC P ABC transporter permease
NPLLMNCH_01584 4.7e-109 glnP P ABC transporter permease
NPLLMNCH_01585 1.1e-164 S Protein of unknown function (DUF2974)
NPLLMNCH_01586 5.6e-86
NPLLMNCH_01587 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
NPLLMNCH_01588 1.3e-235 G Bacterial extracellular solute-binding protein
NPLLMNCH_01589 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
NPLLMNCH_01590 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NPLLMNCH_01591 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NPLLMNCH_01592 0.0 kup P Transport of potassium into the cell
NPLLMNCH_01593 9.1e-175 rihB 3.2.2.1 F Nucleoside
NPLLMNCH_01594 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
NPLLMNCH_01595 1.2e-154 S hydrolase
NPLLMNCH_01596 2.5e-59 S Enterocin A Immunity
NPLLMNCH_01597 3.1e-136 glcR K DeoR C terminal sensor domain
NPLLMNCH_01598 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPLLMNCH_01599 2e-160 rssA S Phospholipase, patatin family
NPLLMNCH_01600 5.4e-147 S hydrolase
NPLLMNCH_01601 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
NPLLMNCH_01602 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
NPLLMNCH_01603 1.6e-80
NPLLMNCH_01604 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
NPLLMNCH_01605 2.1e-39
NPLLMNCH_01606 3.9e-119 C nitroreductase
NPLLMNCH_01607 1.7e-249 yhdP S Transporter associated domain
NPLLMNCH_01608 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
NPLLMNCH_01609 2e-48 MA20_26730 ET Bacterial periplasmic substrate-binding proteins
NPLLMNCH_01610 9.1e-66 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01611 8.1e-175 ulaG S Beta-lactamase superfamily domain
NPLLMNCH_01612 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
NPLLMNCH_01613 2e-232 ulaA S PTS system sugar-specific permease component
NPLLMNCH_01614 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
NPLLMNCH_01615 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
NPLLMNCH_01616 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
NPLLMNCH_01617 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
NPLLMNCH_01618 5.2e-68 L haloacid dehalogenase-like hydrolase
NPLLMNCH_01619 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
NPLLMNCH_01620 1.4e-16 L Transposase
NPLLMNCH_01621 1.9e-12 L Transposase
NPLLMNCH_01622 2.6e-56 K Acetyltransferase (GNAT) domain
NPLLMNCH_01623 1.1e-20 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01624 1.4e-10
NPLLMNCH_01625 5.9e-20 ywjA V ATPases associated with a variety of cellular activities
NPLLMNCH_01626 1.2e-28 sumf2 Q Beta-ketoacyl synthase
NPLLMNCH_01627 2.3e-97 D VirC1 protein
NPLLMNCH_01629 5e-39 relB L RelB antitoxin
NPLLMNCH_01630 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
NPLLMNCH_01631 4.7e-85 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
NPLLMNCH_01632 9.9e-213 V N-6 DNA Methylase
NPLLMNCH_01633 1.6e-27 pepP 3.4.11.9 E aminopeptidase
NPLLMNCH_01634 0.0 1.3.5.4 C FAD binding domain
NPLLMNCH_01635 1.1e-87 L PFAM transposase, IS4 family protein
NPLLMNCH_01636 1.2e-49 L PFAM transposase, IS4 family protein
NPLLMNCH_01637 1.7e-213 1.3.5.4 C FAD binding domain
NPLLMNCH_01638 3.4e-126 1.3.5.4 C FAD binding domain
NPLLMNCH_01639 1e-190 L Transposase and inactivated derivatives, IS30 family
NPLLMNCH_01640 1.8e-79
NPLLMNCH_01641 4e-60 L Resolvase, N terminal domain
NPLLMNCH_01642 2.3e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NPLLMNCH_01643 2.3e-101 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01644 1.8e-132 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NPLLMNCH_01645 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
NPLLMNCH_01646 9.7e-231 potE E amino acid
NPLLMNCH_01647 3.9e-55
NPLLMNCH_01648 2.3e-26
NPLLMNCH_01649 9.5e-220 L Belongs to the 'phage' integrase family
NPLLMNCH_01651 2.5e-62 yfiL V ABC transporter
NPLLMNCH_01652 1.8e-27 S Uncharacterized protein conserved in bacteria (DUF2218)
NPLLMNCH_01653 6e-11 hlyD M TIGRFAM type I secretion membrane fusion protein, HlyD family
NPLLMNCH_01654 1.6e-77 ybhL S Belongs to the BI1 family
NPLLMNCH_01655 2.6e-61 M Glycosyl hydrolases family 25
NPLLMNCH_01656 1.3e-61 M Glycosyl hydrolases family 25
NPLLMNCH_01657 2.8e-211 yfmL 3.6.4.13 L DEAD DEAH box helicase
NPLLMNCH_01658 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_01660 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
NPLLMNCH_01661 1.9e-166 repA S Replication initiator protein A
NPLLMNCH_01662 1.7e-142 soj D AAA domain
NPLLMNCH_01663 1.3e-28
NPLLMNCH_01664 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPLLMNCH_01665 4.7e-70 L IS1381, transposase OrfA
NPLLMNCH_01666 1.1e-109 tnpR1 L Resolvase, N terminal domain
NPLLMNCH_01667 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NPLLMNCH_01668 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPLLMNCH_01670 4.8e-138 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01671 2.8e-48 S Peptidase propeptide and YPEB domain
NPLLMNCH_01672 4e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
NPLLMNCH_01673 2.8e-22 S Protein of unknown function (DUF559)
NPLLMNCH_01674 3.3e-67 T Putative diguanylate phosphodiesterase
NPLLMNCH_01675 1.2e-44 rhiA Q KR domain protein
NPLLMNCH_01676 7e-87 gtcA S Teichoic acid glycosylation protein
NPLLMNCH_01677 4.1e-80 fld C Flavodoxin
NPLLMNCH_01678 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
NPLLMNCH_01679 3.6e-163 yihY S Belongs to the UPF0761 family
NPLLMNCH_01680 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
NPLLMNCH_01681 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
NPLLMNCH_01682 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
NPLLMNCH_01683 5.5e-36 pcaR2 K helix_turn_helix isocitrate lyase regulation
NPLLMNCH_01684 1.4e-98 L Helix-turn-helix domain
NPLLMNCH_01685 3.7e-28 S periplasmic protein
NPLLMNCH_01686 9.4e-46
NPLLMNCH_01687 1.8e-38 D Alpha beta
NPLLMNCH_01688 1.4e-118 D Alpha beta
NPLLMNCH_01689 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NPLLMNCH_01690 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
NPLLMNCH_01691 1.6e-85
NPLLMNCH_01692 2.7e-74
NPLLMNCH_01693 1.4e-140 hlyX S Transporter associated domain
NPLLMNCH_01694 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NPLLMNCH_01695 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
NPLLMNCH_01696 0.0 clpE O Belongs to the ClpA ClpB family
NPLLMNCH_01698 7.7e-48 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPLLMNCH_01701 8.8e-29
NPLLMNCH_01704 4.9e-111 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01705 2.5e-75 K Helix-turn-helix domain
NPLLMNCH_01706 1.5e-25 S CAAX protease self-immunity
NPLLMNCH_01707 1.4e-22 S CAAX protease self-immunity
NPLLMNCH_01708 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01710 1.6e-96 ybaT E Amino acid permease
NPLLMNCH_01711 1.7e-07 S LPXTG cell wall anchor motif
NPLLMNCH_01712 4.4e-146 S Putative ABC-transporter type IV
NPLLMNCH_01714 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NPLLMNCH_01715 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NPLLMNCH_01716 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPLLMNCH_01717 1.2e-232 oppA E ABC transporter substrate-binding protein
NPLLMNCH_01718 2.1e-95 oppA E ABC transporter substrate-binding protein
NPLLMNCH_01719 3.2e-176 K AI-2E family transporter
NPLLMNCH_01720 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
NPLLMNCH_01721 4.1e-18
NPLLMNCH_01722 4.1e-245 G Major Facilitator
NPLLMNCH_01723 1.3e-79 E Zn peptidase
NPLLMNCH_01724 1.2e-41 ps115 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01725 5.6e-45
NPLLMNCH_01726 4.5e-66 S Bacteriocin helveticin-J
NPLLMNCH_01727 1.7e-66 S SLAP domain
NPLLMNCH_01728 5.8e-45
NPLLMNCH_01729 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
NPLLMNCH_01730 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
NPLLMNCH_01731 1.7e-174 ABC-SBP S ABC transporter
NPLLMNCH_01732 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPLLMNCH_01733 1.6e-48 P CorA-like Mg2+ transporter protein
NPLLMNCH_01734 5.2e-75 P CorA-like Mg2+ transporter protein
NPLLMNCH_01735 3.5e-160 yvgN C Aldo keto reductase
NPLLMNCH_01736 0.0 tetP J elongation factor G
NPLLMNCH_01737 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
NPLLMNCH_01738 1.2e-134 EGP Major facilitator Superfamily
NPLLMNCH_01740 6e-51 M Outer membrane protein beta-barrel domain
NPLLMNCH_01741 3.7e-102 L Integrase
NPLLMNCH_01742 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
NPLLMNCH_01743 1.3e-30
NPLLMNCH_01744 5.3e-26
NPLLMNCH_01745 8.5e-41 ptsH G phosphocarrier protein HPR
NPLLMNCH_01746 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NPLLMNCH_01747 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPLLMNCH_01748 8.5e-139 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
NPLLMNCH_01749 1.4e-158 coiA 3.6.4.12 S Competence protein
NPLLMNCH_01750 4.6e-114 yjbH Q Thioredoxin
NPLLMNCH_01751 6.8e-110 yjbK S CYTH
NPLLMNCH_01752 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
NPLLMNCH_01753 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NPLLMNCH_01754 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPLLMNCH_01755 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
NPLLMNCH_01756 4.2e-92 S SNARE associated Golgi protein
NPLLMNCH_01757 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
NPLLMNCH_01758 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
NPLLMNCH_01759 2.6e-214 yubA S AI-2E family transporter
NPLLMNCH_01760 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
NPLLMNCH_01761 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
NPLLMNCH_01762 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
NPLLMNCH_01763 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
NPLLMNCH_01764 1.9e-236 S Peptidase M16
NPLLMNCH_01765 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
NPLLMNCH_01766 5.2e-97 ymfM S Helix-turn-helix domain
NPLLMNCH_01767 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NPLLMNCH_01768 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NPLLMNCH_01769 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
NPLLMNCH_01770 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
NPLLMNCH_01771 5.1e-119 yvyE 3.4.13.9 S YigZ family
NPLLMNCH_01772 4.7e-246 comFA L Helicase C-terminal domain protein
NPLLMNCH_01773 9.4e-132 comFC S Competence protein
NPLLMNCH_01774 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NPLLMNCH_01775 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
NPLLMNCH_01776 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NPLLMNCH_01777 5.1e-17
NPLLMNCH_01778 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NPLLMNCH_01779 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NPLLMNCH_01780 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
NPLLMNCH_01781 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
NPLLMNCH_01782 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
NPLLMNCH_01783 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
NPLLMNCH_01784 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
NPLLMNCH_01785 4.1e-90 S Short repeat of unknown function (DUF308)
NPLLMNCH_01786 6.2e-165 rapZ S Displays ATPase and GTPase activities
NPLLMNCH_01787 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
NPLLMNCH_01788 2.1e-171 whiA K May be required for sporulation
NPLLMNCH_01789 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
NPLLMNCH_01790 0.0 S SH3-like domain
NPLLMNCH_01791 4.9e-111 ybbL S ABC transporter, ATP-binding protein
NPLLMNCH_01792 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
NPLLMNCH_01795 3.1e-48 S Domain of unknown function (DUF4811)
NPLLMNCH_01796 2.3e-260 lmrB EGP Major facilitator Superfamily
NPLLMNCH_01797 4.2e-77 K MerR HTH family regulatory protein
NPLLMNCH_01798 3.1e-139 S Cysteine-rich secretory protein family
NPLLMNCH_01799 1.9e-272 ycaM E amino acid
NPLLMNCH_01800 2.8e-290
NPLLMNCH_01802 3.3e-189 cggR K Putative sugar-binding domain
NPLLMNCH_01803 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
NPLLMNCH_01804 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
NPLLMNCH_01805 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NPLLMNCH_01806 1.2e-94
NPLLMNCH_01807 9.9e-155 ycsE S Sucrose-6F-phosphate phosphohydrolase
NPLLMNCH_01808 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NPLLMNCH_01809 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
NPLLMNCH_01810 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
NPLLMNCH_01811 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
NPLLMNCH_01812 2e-163 murB 1.3.1.98 M Cell wall formation
NPLLMNCH_01813 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
NPLLMNCH_01814 1.3e-129 potB P ABC transporter permease
NPLLMNCH_01815 4.8e-127 potC P ABC transporter permease
NPLLMNCH_01816 7.3e-208 potD P ABC transporter
NPLLMNCH_01817 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NPLLMNCH_01818 2e-172 ybbR S YbbR-like protein
NPLLMNCH_01819 9e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NPLLMNCH_01820 1.4e-147 S hydrolase
NPLLMNCH_01821 1.8e-75 K Penicillinase repressor
NPLLMNCH_01822 1.6e-118
NPLLMNCH_01823 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NPLLMNCH_01824 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
NPLLMNCH_01825 8.3e-143 licT K CAT RNA binding domain
NPLLMNCH_01826 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
NPLLMNCH_01827 1e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPLLMNCH_01828 1e-149 D Alpha beta
NPLLMNCH_01829 6.2e-102 L An automated process has identified a potential problem with this gene model
NPLLMNCH_01830 2.4e-34 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
NPLLMNCH_01831 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
NPLLMNCH_01832 5.2e-112 ica2 GT2 M Glycosyl transferase family group 2
NPLLMNCH_01833 8.2e-36
NPLLMNCH_01834 2.2e-90 2.7.7.65 T GGDEF domain
NPLLMNCH_01835 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
NPLLMNCH_01837 2e-310 E Amino acid permease
NPLLMNCH_01838 5.8e-100 L Helix-turn-helix domain
NPLLMNCH_01839 1.3e-160 L hmm pf00665
NPLLMNCH_01841 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NPLLMNCH_01842 3.5e-101 ylbE GM NAD(P)H-binding
NPLLMNCH_01843 7.6e-94 S VanZ like family
NPLLMNCH_01844 8.9e-133 yebC K Transcriptional regulatory protein
NPLLMNCH_01845 1.7e-179 comGA NU Type II IV secretion system protein
NPLLMNCH_01846 1.7e-171 comGB NU type II secretion system
NPLLMNCH_01847 3.1e-43 comGC U competence protein ComGC
NPLLMNCH_01848 1.8e-69
NPLLMNCH_01849 2.3e-41
NPLLMNCH_01850 3.8e-77 comGF U Putative Competence protein ComGF
NPLLMNCH_01851 1.6e-21
NPLLMNCH_01852 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
NPLLMNCH_01853 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NPLLMNCH_01855 3e-148 L Belongs to the 'phage' integrase family
NPLLMNCH_01856 2.6e-09 S Pfam:DUF955
NPLLMNCH_01857 1.1e-17 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01858 2.6e-21 2.3.1.19 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01859 9.8e-26 K Helix-turn-helix domain
NPLLMNCH_01861 4.1e-09 S Arc-like DNA binding domain
NPLLMNCH_01863 4e-21 K Conserved phage C-terminus (Phg_2220_C)
NPLLMNCH_01864 1.5e-26 S Domain of unknown function (DUF771)
NPLLMNCH_01872 3.6e-34 S Phage derived protein Gp49-like (DUF891)
NPLLMNCH_01873 7.1e-35 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_01875 1.1e-188 L N-6 DNA Methylase
NPLLMNCH_01876 2.2e-26 S Type I restriction modification DNA specificity domain
NPLLMNCH_01877 5.7e-11 S Single-strand binding protein family
NPLLMNCH_01884 1.6e-18 S SLAP domain
NPLLMNCH_01885 1.8e-24 srtA 3.4.22.70 M sortase family
NPLLMNCH_01887 5.6e-40 M domain protein
NPLLMNCH_01888 7.2e-15 S SLAP domain
NPLLMNCH_01889 6.4e-33 M domain protein
NPLLMNCH_01893 4e-141 U TraM recognition site of TraD and TraG
NPLLMNCH_01894 3.9e-32 I mechanosensitive ion channel activity
NPLLMNCH_01896 2.4e-14
NPLLMNCH_01897 1.8e-159 trsE S COG0433 Predicted ATPase
NPLLMNCH_01898 1.2e-32 M Peptidase family M23
NPLLMNCH_01901 3.4e-17 CO COG0526, thiol-disulfide isomerase and thioredoxins
NPLLMNCH_01904 2.5e-89 M Protein of unknown function (DUF3737)
NPLLMNCH_01905 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
NPLLMNCH_01906 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
NPLLMNCH_01907 7.7e-67 S SdpI/YhfL protein family
NPLLMNCH_01908 4.4e-129 K Transcriptional regulatory protein, C terminal
NPLLMNCH_01909 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
NPLLMNCH_01910 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
NPLLMNCH_01911 1.1e-104 vanZ V VanZ like family
NPLLMNCH_01912 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
NPLLMNCH_01913 4.9e-217 EGP Major facilitator Superfamily
NPLLMNCH_01914 1.7e-195 ampC V Beta-lactamase
NPLLMNCH_01917 2.8e-40 M Sulfatase
NPLLMNCH_01918 4.3e-24 S SLAP domain
NPLLMNCH_01919 7.6e-25 S SLAP domain
NPLLMNCH_01921 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
NPLLMNCH_01922 1.4e-14
NPLLMNCH_01923 2.6e-71 S Evidence 4 Homologs of previously reported genes of
NPLLMNCH_01924 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
NPLLMNCH_01925 1.7e-113 tdk 2.7.1.21 F thymidine kinase
NPLLMNCH_01926 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NPLLMNCH_01927 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
NPLLMNCH_01928 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
NPLLMNCH_01929 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NPLLMNCH_01930 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
NPLLMNCH_01931 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPLLMNCH_01932 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NPLLMNCH_01933 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NPLLMNCH_01934 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NPLLMNCH_01935 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NPLLMNCH_01936 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NPLLMNCH_01937 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
NPLLMNCH_01938 2e-30 ywzB S Protein of unknown function (DUF1146)
NPLLMNCH_01939 1.2e-177 mbl D Cell shape determining protein MreB Mrl
NPLLMNCH_01940 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
NPLLMNCH_01941 3.3e-33 S Protein of unknown function (DUF2969)
NPLLMNCH_01942 4.7e-216 rodA D Belongs to the SEDS family
NPLLMNCH_01943 1.8e-78 usp6 T universal stress protein
NPLLMNCH_01944 8.4e-39
NPLLMNCH_01945 6.3e-238 rarA L recombination factor protein RarA
NPLLMNCH_01946 1.3e-84 yueI S Protein of unknown function (DUF1694)
NPLLMNCH_01947 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NPLLMNCH_01948 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
NPLLMNCH_01949 6.2e-213 iscS2 2.8.1.7 E Aminotransferase class V
NPLLMNCH_01950 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NPLLMNCH_01951 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
NPLLMNCH_01952 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPLLMNCH_01953 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
NPLLMNCH_01954 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
NPLLMNCH_01955 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
NPLLMNCH_01956 1.5e-94 S Protein of unknown function (DUF3990)
NPLLMNCH_01957 6.5e-44
NPLLMNCH_01959 0.0 3.6.3.8 P P-type ATPase
NPLLMNCH_01960 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
NPLLMNCH_01961 2.5e-52
NPLLMNCH_01962 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
NPLLMNCH_01963 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
NPLLMNCH_01964 5.7e-126 S Haloacid dehalogenase-like hydrolase
NPLLMNCH_01965 2.3e-108 radC L DNA repair protein
NPLLMNCH_01966 2.4e-176 mreB D cell shape determining protein MreB
NPLLMNCH_01967 2e-147 mreC M Involved in formation and maintenance of cell shape
NPLLMNCH_01968 2.7e-94 mreD
NPLLMNCH_01969 2.3e-268 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
NPLLMNCH_01971 6.4e-54 S Protein of unknown function (DUF3397)
NPLLMNCH_01972 6.3e-78 mraZ K Belongs to the MraZ family
NPLLMNCH_01973 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
NPLLMNCH_01974 1.8e-54 ftsL D Cell division protein FtsL
NPLLMNCH_01975 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
NPLLMNCH_01976 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NPLLMNCH_01977 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NPLLMNCH_01978 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NPLLMNCH_01979 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
NPLLMNCH_01980 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
NPLLMNCH_01981 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NPLLMNCH_01982 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
NPLLMNCH_01983 1.7e-45 yggT S YGGT family
NPLLMNCH_01984 5.7e-149 ylmH S S4 domain protein
NPLLMNCH_01985 2.8e-74 gpsB D DivIVA domain protein
NPLLMNCH_01986 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NPLLMNCH_01987 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
NPLLMNCH_01988 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
NPLLMNCH_01989 6.7e-37
NPLLMNCH_01990 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NPLLMNCH_01991 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
NPLLMNCH_01992 5.4e-56 XK27_04120 S Putative amino acid metabolism
NPLLMNCH_01993 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
NPLLMNCH_01994 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
NPLLMNCH_01995 8.3e-106 S Repeat protein
NPLLMNCH_01996 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
NPLLMNCH_01997 1.6e-294 L Nuclease-related domain
NPLLMNCH_01998 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
NPLLMNCH_01999 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPLLMNCH_02000 3.5e-32 ykzG S Belongs to the UPF0356 family
NPLLMNCH_02001 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
NPLLMNCH_02002 0.0 typA T GTP-binding protein TypA
NPLLMNCH_02003 5.9e-211 ftsW D Belongs to the SEDS family
NPLLMNCH_02004 8.7e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
NPLLMNCH_02005 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
NPLLMNCH_02006 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NPLLMNCH_02007 2.4e-187 ylbL T Belongs to the peptidase S16 family
NPLLMNCH_02008 3.1e-79 comEA L Competence protein ComEA
NPLLMNCH_02009 0.0 comEC S Competence protein ComEC
NPLLMNCH_02010 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
NPLLMNCH_02011 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
NPLLMNCH_02012 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NPLLMNCH_02013 3e-310 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NPLLMNCH_02014 1.3e-148
NPLLMNCH_02015 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NPLLMNCH_02016 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
NPLLMNCH_02017 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NPLLMNCH_02018 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
NPLLMNCH_02019 7.8e-39 yjeM E Amino Acid
NPLLMNCH_02020 3.4e-175 yjeM E Amino Acid
NPLLMNCH_02021 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NPLLMNCH_02022 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPLLMNCH_02023 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
NPLLMNCH_02024 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
NPLLMNCH_02025 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
NPLLMNCH_02026 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NPLLMNCH_02027 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
NPLLMNCH_02028 2.7e-216 aspC 2.6.1.1 E Aminotransferase
NPLLMNCH_02029 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NPLLMNCH_02030 2.1e-194 pbpX1 V Beta-lactamase
NPLLMNCH_02031 5e-243 I Protein of unknown function (DUF2974)
NPLLMNCH_02032 1.1e-12 I Alpha/beta hydrolase family
NPLLMNCH_02033 1.5e-80
NPLLMNCH_02034 1.6e-73 marR K Transcriptional regulator, MarR family
NPLLMNCH_02035 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NPLLMNCH_02036 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPLLMNCH_02037 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NPLLMNCH_02038 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
NPLLMNCH_02039 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
NPLLMNCH_02040 2.9e-107 IQ reductase
NPLLMNCH_02041 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
NPLLMNCH_02042 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NPLLMNCH_02043 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
NPLLMNCH_02044 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
NPLLMNCH_02045 6.3e-138 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NPLLMNCH_02046 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
NPLLMNCH_02047 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
NPLLMNCH_02048 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
NPLLMNCH_02049 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPLLMNCH_02052 1.8e-158 xth 3.1.11.2 L exodeoxyribonuclease III
NPLLMNCH_02053 1.3e-273 E amino acid
NPLLMNCH_02054 0.0 L Helicase C-terminal domain protein
NPLLMNCH_02055 4.8e-205 pbpX1 V Beta-lactamase
NPLLMNCH_02056 5.1e-226 N Uncharacterized conserved protein (DUF2075)
NPLLMNCH_02057 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
NPLLMNCH_02058 3.6e-39 C FMN_bind
NPLLMNCH_02059 1.5e-81
NPLLMNCH_02060 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
NPLLMNCH_02061 2e-85 alkD L DNA alkylation repair enzyme
NPLLMNCH_02062 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPLLMNCH_02063 6.4e-128 K UTRA domain
NPLLMNCH_02064 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
NPLLMNCH_02065 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
NPLLMNCH_02066 9.4e-23 S Ketosteroid isomerase-related protein
NPLLMNCH_02067 6.9e-72
NPLLMNCH_02068 7.9e-71 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_02069 2.4e-36 L An automated process has identified a potential problem with this gene model
NPLLMNCH_02070 2e-43 MA20_45165 S Domain of unknown function (DUF892)
NPLLMNCH_02071 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_02072 3.5e-70 S Domain of unknown function (DUF3284)
NPLLMNCH_02073 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPLLMNCH_02074 3.7e-131 gmuR K UTRA
NPLLMNCH_02075 9.3e-41
NPLLMNCH_02076 3.1e-64 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NPLLMNCH_02077 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_02078 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
NPLLMNCH_02079 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPLLMNCH_02080 3.7e-199 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
NPLLMNCH_02081 6.8e-156 ypbG 2.7.1.2 GK ROK family
NPLLMNCH_02082 1.4e-39 L Transposase and inactivated derivatives, IS30 family
NPLLMNCH_02083 1.8e-73 C nitroreductase
NPLLMNCH_02084 5.1e-11 S Domain of unknown function (DUF4767)
NPLLMNCH_02085 3.1e-08 corA P CorA-like Mg2+ transporter protein
NPLLMNCH_02086 8.4e-56 S Domain of unknown function (DUF4767)
NPLLMNCH_02087 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
NPLLMNCH_02088 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
NPLLMNCH_02089 3.2e-101 3.6.1.27 I Acid phosphatase homologues
NPLLMNCH_02090 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
NPLLMNCH_02092 2e-178 MA20_14895 S Conserved hypothetical protein 698
NPLLMNCH_02093 1.1e-83 dps P Belongs to the Dps family
NPLLMNCH_02094 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
NPLLMNCH_02095 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
NPLLMNCH_02096 1.8e-58 S Putative adhesin
NPLLMNCH_02097 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
NPLLMNCH_02098 2e-234 mepA V MATE efflux family protein
NPLLMNCH_02099 6.7e-59 L Transposase and inactivated derivatives, IS30 family
NPLLMNCH_02100 5.8e-13 L Transposase and inactivated derivatives, IS30 family
NPLLMNCH_02101 2.4e-10 L Psort location Cytoplasmic, score
NPLLMNCH_02102 4e-89 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
NPLLMNCH_02104 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
NPLLMNCH_02105 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
NPLLMNCH_02106 1.4e-36 S Cytochrome B5
NPLLMNCH_02107 6e-168 arbZ I Phosphate acyltransferases
NPLLMNCH_02108 1.6e-182 arbY M Glycosyl transferase family 8
NPLLMNCH_02109 5e-184 arbY M Glycosyl transferase family 8
NPLLMNCH_02110 5e-156 arbx M Glycosyl transferase family 8
NPLLMNCH_02111 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
NPLLMNCH_02113 4.9e-34
NPLLMNCH_02115 4.8e-131 K response regulator
NPLLMNCH_02116 2.2e-305 vicK 2.7.13.3 T Histidine kinase
NPLLMNCH_02117 1.6e-257 yycH S YycH protein
NPLLMNCH_02118 3.4e-149 yycI S YycH protein
NPLLMNCH_02119 4.1e-147 vicX 3.1.26.11 S domain protein
NPLLMNCH_02120 1.6e-161 htrA 3.4.21.107 O serine protease
NPLLMNCH_02121 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NPLLMNCH_02122 1.6e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
NPLLMNCH_02123 4.7e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
NPLLMNCH_02124 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
NPLLMNCH_02125 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NPLLMNCH_02126 2.2e-120 lsa S ABC transporter
NPLLMNCH_02127 2.7e-83 S Protein of unknown function (DUF1211)
NPLLMNCH_02128 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
NPLLMNCH_02129 2.8e-119 3.6.1.55 F NUDIX domain
NPLLMNCH_02130 3.9e-246 brnQ U Component of the transport system for branched-chain amino acids
NPLLMNCH_02131 0.0 L Plasmid pRiA4b ORF-3-like protein
NPLLMNCH_02132 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
NPLLMNCH_02133 2.5e-08 S Protein of unknown function (DUF3021)
NPLLMNCH_02134 9e-34 K Bacterial regulatory helix-turn-helix protein, lysR family
NPLLMNCH_02135 4.2e-63 lmrB EGP Major facilitator Superfamily
NPLLMNCH_02136 2.9e-122 rbtT P Major Facilitator Superfamily
NPLLMNCH_02137 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
NPLLMNCH_02138 2.5e-86 K GNAT family
NPLLMNCH_02139 1.5e-10 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPLLMNCH_02140 4.3e-58 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
NPLLMNCH_02142 4.3e-36
NPLLMNCH_02143 6.2e-288 P ABC transporter
NPLLMNCH_02144 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_02145 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_02146 1.2e-250 yifK E Amino acid permease
NPLLMNCH_02147 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NPLLMNCH_02148 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NPLLMNCH_02149 0.0 aha1 P E1-E2 ATPase
NPLLMNCH_02150 2.4e-175 F DNA/RNA non-specific endonuclease
NPLLMNCH_02151 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
NPLLMNCH_02152 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NPLLMNCH_02153 3.4e-73 metI P ABC transporter permease
NPLLMNCH_02154 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
NPLLMNCH_02155 1.9e-261 frdC 1.3.5.4 C FAD binding domain
NPLLMNCH_02156 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
NPLLMNCH_02157 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
NPLLMNCH_02158 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
NPLLMNCH_02159 5.7e-272 P Sodium:sulfate symporter transmembrane region
NPLLMNCH_02160 1.7e-153 ydjP I Alpha/beta hydrolase family
NPLLMNCH_02161 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
NPLLMNCH_02162 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
NPLLMNCH_02163 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
NPLLMNCH_02164 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
NPLLMNCH_02165 9.3e-72 yeaL S Protein of unknown function (DUF441)
NPLLMNCH_02166 3.5e-21
NPLLMNCH_02167 3.6e-146 cbiQ P cobalt transport
NPLLMNCH_02168 0.0 ykoD P ABC transporter, ATP-binding protein
NPLLMNCH_02169 1.5e-95 S UPF0397 protein
NPLLMNCH_02170 2.9e-66 S Domain of unknown function DUF1828
NPLLMNCH_02171 5.5e-09
NPLLMNCH_02172 1.2e-45
NPLLMNCH_02173 2.6e-177 citR K Putative sugar-binding domain
NPLLMNCH_02174 6.5e-249 yjjP S Putative threonine/serine exporter
NPLLMNCH_02176 5.9e-37 M domain protein
NPLLMNCH_02177 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NPLLMNCH_02178 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
NPLLMNCH_02179 8.5e-60
NPLLMNCH_02180 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NPLLMNCH_02181 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
NPLLMNCH_02182 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
NPLLMNCH_02183 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
NPLLMNCH_02184 1.2e-222 patA 2.6.1.1 E Aminotransferase
NPLLMNCH_02186 8.4e-25 G Peptidase_C39 like family
NPLLMNCH_02187 2.8e-162 M NlpC/P60 family
NPLLMNCH_02188 6.5e-91 G Peptidase_C39 like family
NPLLMNCH_02189 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
NPLLMNCH_02190 2.8e-77 P Cobalt transport protein
NPLLMNCH_02191 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
NPLLMNCH_02192 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NPLLMNCH_02193 4.8e-34 S reductase
NPLLMNCH_02194 4.4e-39 S reductase
NPLLMNCH_02195 2.7e-32 S reductase
NPLLMNCH_02196 1.3e-148 yxeH S hydrolase
NPLLMNCH_02197 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NPLLMNCH_02198 1.1e-243 yfnA E Amino Acid
NPLLMNCH_02199 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
NPLLMNCH_02200 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
NPLLMNCH_02201 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NPLLMNCH_02202 2.2e-292 I Acyltransferase
NPLLMNCH_02203 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
NPLLMNCH_02204 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
NPLLMNCH_02205 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
NPLLMNCH_02206 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
NPLLMNCH_02207 6.1e-131 sip L Belongs to the 'phage' integrase family
NPLLMNCH_02210 1.6e-22 S Hypothetical protein (DUF2513)
NPLLMNCH_02211 7.4e-20 S Pfam:Peptidase_M78
NPLLMNCH_02212 2.8e-20 ps115 K sequence-specific DNA binding
NPLLMNCH_02215 1.4e-16
NPLLMNCH_02216 6.5e-17 K Helix-turn-helix XRE-family like proteins
NPLLMNCH_02217 4e-75 S Phage antirepressor protein KilAC domain
NPLLMNCH_02218 1.4e-14
NPLLMNCH_02224 5e-30 S HNH endonuclease
NPLLMNCH_02225 6.1e-70 S AAA domain
NPLLMNCH_02227 4.3e-149 res L Helicase C-terminal domain protein
NPLLMNCH_02229 6e-41 S Protein of unknown function (DUF669)
NPLLMNCH_02230 1.3e-273 S Phage plasmid primase, P4
NPLLMNCH_02234 4.3e-14 S Phage Terminase
NPLLMNCH_02236 1.5e-134 S Phage portal protein
NPLLMNCH_02237 1.8e-66 S Clp protease
NPLLMNCH_02238 2.6e-145 S peptidase activity
NPLLMNCH_02239 1.9e-21 S Phage gp6-like head-tail connector protein
NPLLMNCH_02241 8.8e-11 S Bacteriophage HK97-gp10, putative tail-component
NPLLMNCH_02243 3.1e-13 S Pfam:Phage_TTP_1
NPLLMNCH_02246 1.5e-130 xkdO D NLP P60 protein
NPLLMNCH_02247 3.6e-31 S phage tail
NPLLMNCH_02248 8e-246 S Phage minor structural protein
NPLLMNCH_02250 1.3e-11 S Domain of unknown function (DUF2479)
NPLLMNCH_02252 1.4e-17 GT2,GT4 LM gp58-like protein
NPLLMNCH_02256 4.9e-24
NPLLMNCH_02258 1.4e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
NPLLMNCH_02259 1.3e-115 M hydrolase, family 25
NPLLMNCH_02261 6.8e-10
NPLLMNCH_02262 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
NPLLMNCH_02263 2.3e-23 S Protein of unknown function (DUF2929)
NPLLMNCH_02264 0.0 dnaE 2.7.7.7 L DNA polymerase
NPLLMNCH_02265 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
NPLLMNCH_02266 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
NPLLMNCH_02267 1e-167 cvfB S S1 domain
NPLLMNCH_02268 2.9e-165 xerD D recombinase XerD
NPLLMNCH_02269 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPLLMNCH_02270 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NPLLMNCH_02271 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NPLLMNCH_02272 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
NPLLMNCH_02273 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NPLLMNCH_02274 2.7e-18 M Lysin motif
NPLLMNCH_02275 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
NPLLMNCH_02276 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
NPLLMNCH_02277 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
NPLLMNCH_02278 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
NPLLMNCH_02279 3.9e-229 S Tetratricopeptide repeat protein
NPLLMNCH_02280 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NPLLMNCH_02281 4.5e-94 rimL J Acetyltransferase (GNAT) domain
NPLLMNCH_02282 9.7e-133 S Alpha/beta hydrolase family
NPLLMNCH_02283 1.7e-36 yxaM EGP Major facilitator Superfamily
NPLLMNCH_02284 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
NPLLMNCH_02285 1e-79 S AAA domain
NPLLMNCH_02286 3.3e-61 3.6.1.55 F NUDIX domain
NPLLMNCH_02287 1.9e-138 2.4.2.3 F Phosphorylase superfamily
NPLLMNCH_02288 9e-144 2.4.2.3 F Phosphorylase superfamily
NPLLMNCH_02289 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
NPLLMNCH_02291 3.7e-27 L Transposase
NPLLMNCH_02292 9.7e-65 yagE E amino acid
NPLLMNCH_02293 8.4e-128 yagE E Amino acid permease
NPLLMNCH_02294 4.3e-86 3.4.21.96 S SLAP domain
NPLLMNCH_02295 8.8e-159 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPLLMNCH_02296 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
NPLLMNCH_02297 1.2e-107 hlyIII S protein, hemolysin III
NPLLMNCH_02298 2e-144 DegV S Uncharacterised protein, DegV family COG1307
NPLLMNCH_02299 7.1e-36 yozE S Belongs to the UPF0346 family
NPLLMNCH_02300 1.1e-66 yjcE P NhaP-type Na H and K H
NPLLMNCH_02301 1.5e-40 yjcE P Sodium proton antiporter
NPLLMNCH_02302 1.9e-94 yjcE P Sodium proton antiporter
NPLLMNCH_02303 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NPLLMNCH_02304 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NPLLMNCH_02305 5.8e-152 dprA LU DNA protecting protein DprA
NPLLMNCH_02306 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NPLLMNCH_02307 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NPLLMNCH_02308 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
NPLLMNCH_02309 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NPLLMNCH_02310 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NPLLMNCH_02311 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
NPLLMNCH_02312 1.4e-86 C Aldo keto reductase
NPLLMNCH_02313 3.8e-48 M LysM domain protein
NPLLMNCH_02314 2.9e-15 M LysM domain protein
NPLLMNCH_02315 2.7e-26 L hmm pf00665
NPLLMNCH_02316 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
NPLLMNCH_02317 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPLLMNCH_02318 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NPLLMNCH_02319 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPLLMNCH_02320 1.4e-115 mmuP E amino acid
NPLLMNCH_02321 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
NPLLMNCH_02322 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
NPLLMNCH_02323 1.7e-284 E Amino acid permease
NPLLMNCH_02324 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
NPLLMNCH_02325 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
NPLLMNCH_02326 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
NPLLMNCH_02327 9.9e-82 C Flavodoxin
NPLLMNCH_02328 0.0 uvrA3 L excinuclease ABC, A subunit
NPLLMNCH_02329 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
NPLLMNCH_02330 2.1e-114 3.6.1.27 I Acid phosphatase homologues
NPLLMNCH_02331 7.4e-205 L COG2826 Transposase and inactivated derivatives, IS30 family
NPLLMNCH_02332 1.9e-80 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
NPLLMNCH_02333 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
NPLLMNCH_02334 9.3e-204 pbpX1 V Beta-lactamase
NPLLMNCH_02335 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
NPLLMNCH_02336 7.5e-95 S ECF-type riboflavin transporter, S component
NPLLMNCH_02337 1.3e-229 S Putative peptidoglycan binding domain
NPLLMNCH_02338 9e-83 K Acetyltransferase (GNAT) domain
NPLLMNCH_02339 2.2e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPLLMNCH_02340 1.9e-191 yrvN L AAA C-terminal domain
NPLLMNCH_02341 8.2e-64 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
NPLLMNCH_02342 3.3e-283 treB G phosphotransferase system
NPLLMNCH_02343 1.2e-100 treR K UTRA
NPLLMNCH_02344 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
NPLLMNCH_02345 5.7e-18
NPLLMNCH_02346 1.5e-239 G Bacterial extracellular solute-binding protein
NPLLMNCH_02347 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
NPLLMNCH_02348 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
NPLLMNCH_02350 0.0 S SLAP domain
NPLLMNCH_02351 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
NPLLMNCH_02352 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
NPLLMNCH_02353 3.4e-42 S RloB-like protein
NPLLMNCH_02354 1.2e-258 hsdM 2.1.1.72 V type I restriction-modification system
NPLLMNCH_02355 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
NPLLMNCH_02356 1.2e-63 S SIR2-like domain
NPLLMNCH_02357 3.2e-10 S Domain of unknown function DUF87
NPLLMNCH_02358 2e-75 S cog cog0433
NPLLMNCH_02359 1.9e-110 F DNA/RNA non-specific endonuclease
NPLLMNCH_02360 2.7e-34 S YSIRK type signal peptide
NPLLMNCH_02362 5.5e-53
NPLLMNCH_02363 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
NPLLMNCH_02364 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NPLLMNCH_02365 4.3e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
NPLLMNCH_02366 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
NPLLMNCH_02367 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
NPLLMNCH_02368 0.0 FbpA K Fibronectin-binding protein
NPLLMNCH_02369 1.1e-66
NPLLMNCH_02370 1.3e-159 degV S EDD domain protein, DegV family
NPLLMNCH_02371 1.1e-24 L Transposase
NPLLMNCH_02372 7.2e-92 K helix_turn_helix, arabinose operon control protein
NPLLMNCH_02373 3.2e-68 K helix_turn_helix, arabinose operon control protein
NPLLMNCH_02374 8.3e-157 htpX O Belongs to the peptidase M48B family
NPLLMNCH_02375 5.1e-96 lemA S LemA family
NPLLMNCH_02376 7.5e-192 ybiR P Citrate transporter
NPLLMNCH_02377 2e-70 S Iron-sulphur cluster biosynthesis
NPLLMNCH_02378 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
NPLLMNCH_02379 1.2e-17
NPLLMNCH_02380 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
NPLLMNCH_02381 5.4e-203 xerS L Belongs to the 'phage' integrase family
NPLLMNCH_02382 4.1e-67
NPLLMNCH_02383 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
NPLLMNCH_02384 5.8e-211 M Glycosyl hydrolases family 25
NPLLMNCH_02385 2.1e-39 S Transglycosylase associated protein
NPLLMNCH_02386 6.9e-122 yoaK S Protein of unknown function (DUF1275)
NPLLMNCH_02387 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
NPLLMNCH_02388 1.3e-12 L TIGRFAM transposase, IS605 OrfB family
NPLLMNCH_02389 1.2e-11 S Transposase C of IS166 homeodomain
NPLLMNCH_02390 1.4e-59 XK27_01125 L IS66 Orf2 like protein
NPLLMNCH_02392 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
NPLLMNCH_02393 2.8e-182 K Transcriptional regulator
NPLLMNCH_02394 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPLLMNCH_02395 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
NPLLMNCH_02396 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
NPLLMNCH_02397 0.0 snf 2.7.11.1 KL domain protein
NPLLMNCH_02398 2e-35
NPLLMNCH_02400 3.8e-104 pncA Q Isochorismatase family
NPLLMNCH_02401 4.9e-118
NPLLMNCH_02404 3.6e-63
NPLLMNCH_02405 1.4e-34
NPLLMNCH_02406 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
NPLLMNCH_02407 3.4e-79
NPLLMNCH_02408 1e-242 cpdA S Calcineurin-like phosphoesterase
NPLLMNCH_02409 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
NPLLMNCH_02410 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
NPLLMNCH_02411 1e-107 ypsA S Belongs to the UPF0398 family
NPLLMNCH_02412 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
NPLLMNCH_02413 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
NPLLMNCH_02414 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NPLLMNCH_02415 1.3e-114 dnaD L DnaD domain protein
NPLLMNCH_02416 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
NPLLMNCH_02417 2.4e-89 ypmB S Protein conserved in bacteria
NPLLMNCH_02418 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
NPLLMNCH_02419 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
NPLLMNCH_02420 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
NPLLMNCH_02421 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
NPLLMNCH_02422 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
NPLLMNCH_02423 2.1e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
NPLLMNCH_02424 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
NPLLMNCH_02425 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
NPLLMNCH_02426 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
NPLLMNCH_02427 9.7e-169
NPLLMNCH_02428 7.5e-143
NPLLMNCH_02429 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
NPLLMNCH_02430 1.4e-26
NPLLMNCH_02431 6.7e-145
NPLLMNCH_02432 5.1e-137
NPLLMNCH_02433 4.5e-141
NPLLMNCH_02434 9.6e-124 skfE V ATPases associated with a variety of cellular activities
NPLLMNCH_02435 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
NPLLMNCH_02436 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
NPLLMNCH_02437 1.2e-151 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NPLLMNCH_02438 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
NPLLMNCH_02439 4.8e-81 mutT 3.6.1.55 F NUDIX domain
NPLLMNCH_02440 1.4e-127 S Peptidase family M23
NPLLMNCH_02441 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
NPLLMNCH_02442 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
NPLLMNCH_02443 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
NPLLMNCH_02444 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
NPLLMNCH_02445 4.4e-135 recO L Involved in DNA repair and RecF pathway recombination
NPLLMNCH_02446 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NPLLMNCH_02447 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NPLLMNCH_02448 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
NPLLMNCH_02449 3.5e-71 yqeY S YqeY-like protein
NPLLMNCH_02450 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
NPLLMNCH_02451 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
NPLLMNCH_02452 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
NPLLMNCH_02453 1.3e-116 S Peptidase family M23
NPLLMNCH_02454 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NPLLMNCH_02456 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
NPLLMNCH_02457 9.4e-118
NPLLMNCH_02458 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
NPLLMNCH_02459 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
NPLLMNCH_02460 2.6e-280 thrC 4.2.3.1 E Threonine synthase
NPLLMNCH_02461 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
NPLLMNCH_02462 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
NPLLMNCH_02463 0.0 L PLD-like domain
NPLLMNCH_02464 4.8e-42 S SnoaL-like domain
NPLLMNCH_02465 5.4e-53 hipB K sequence-specific DNA binding
NPLLMNCH_02466 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
NPLLMNCH_02467 3.4e-27
NPLLMNCH_02468 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_02469 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
NPLLMNCH_02470 1.7e-96 L Transposase
NPLLMNCH_02471 1.4e-94
NPLLMNCH_02472 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
NPLLMNCH_02473 9e-98
NPLLMNCH_02474 4.9e-108 K LysR substrate binding domain
NPLLMNCH_02475 1e-20
NPLLMNCH_02476 2.3e-215 S Sterol carrier protein domain
NPLLMNCH_02477 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
NPLLMNCH_02478 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
NPLLMNCH_02479 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NPLLMNCH_02480 5.7e-233 arcA 3.5.3.6 E Arginine
NPLLMNCH_02481 9e-137 lysR5 K LysR substrate binding domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)