ORF_ID e_value Gene_name EC_number CAZy COGs Description
HMOKDKBH_00001 6.2e-276 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMOKDKBH_00002 9.5e-31
HMOKDKBH_00003 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HMOKDKBH_00004 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HMOKDKBH_00005 2.1e-252 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMOKDKBH_00006 1.2e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMOKDKBH_00007 2.7e-61 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HMOKDKBH_00008 1.1e-15 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HMOKDKBH_00009 1.6e-244 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMOKDKBH_00010 4.2e-182 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HMOKDKBH_00011 2.6e-35 yaaA S S4 domain protein YaaA
HMOKDKBH_00012 1.1e-209 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMOKDKBH_00013 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMOKDKBH_00014 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HMOKDKBH_00015 9.4e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HMOKDKBH_00016 4.5e-78 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HMOKDKBH_00017 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMOKDKBH_00018 4.5e-189 ydaM M Glycosyl transferase
HMOKDKBH_00019 4e-177 G Glycosyl hydrolases family 8
HMOKDKBH_00020 1e-119 yfbR S HD containing hydrolase-like enzyme
HMOKDKBH_00021 6.4e-159 L HNH nucleases
HMOKDKBH_00022 3.3e-131 S Protein of unknown function (DUF805)
HMOKDKBH_00023 1.9e-39 S Transglycosylase associated protein
HMOKDKBH_00024 6.9e-122 yoaK S Protein of unknown function (DUF1275)
HMOKDKBH_00025 1.3e-12 L TIGRFAM transposase, IS605 OrfB family
HMOKDKBH_00026 1.2e-11 S Transposase C of IS166 homeodomain
HMOKDKBH_00027 1.4e-59 XK27_01125 L IS66 Orf2 like protein
HMOKDKBH_00029 4.4e-169 ppaC 3.6.1.1 C inorganic pyrophosphatase
HMOKDKBH_00030 2.8e-182 K Transcriptional regulator
HMOKDKBH_00031 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMOKDKBH_00032 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HMOKDKBH_00033 3.5e-109 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMOKDKBH_00034 0.0 snf 2.7.11.1 KL domain protein
HMOKDKBH_00035 2e-35
HMOKDKBH_00037 3.8e-104 pncA Q Isochorismatase family
HMOKDKBH_00038 4.9e-118
HMOKDKBH_00041 3.6e-63
HMOKDKBH_00042 1.4e-34
HMOKDKBH_00043 1.9e-115 rdgB 3.6.1.66, 5.1.1.3 F Ham1 family
HMOKDKBH_00044 3.4e-79
HMOKDKBH_00045 1e-242 cpdA S Calcineurin-like phosphoesterase
HMOKDKBH_00046 3.6e-218 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HMOKDKBH_00047 1.1e-68 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HMOKDKBH_00048 1e-107 ypsA S Belongs to the UPF0398 family
HMOKDKBH_00049 4.5e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HMOKDKBH_00050 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMOKDKBH_00051 2.7e-114 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMOKDKBH_00052 1.3e-114 dnaD L DnaD domain protein
HMOKDKBH_00053 5.8e-260 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HMOKDKBH_00054 2.4e-89 ypmB S Protein conserved in bacteria
HMOKDKBH_00055 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HMOKDKBH_00056 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HMOKDKBH_00057 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HMOKDKBH_00058 4.8e-136 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I GHMP kinases N terminal domain
HMOKDKBH_00059 1.4e-178 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HMOKDKBH_00060 4.6e-202 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HMOKDKBH_00061 6.9e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HMOKDKBH_00062 1.3e-116 3.1.3.102, 3.1.3.104, 3.1.3.23 G Sucrose-6F-phosphate phosphohydrolase
HMOKDKBH_00063 8.3e-265 rsmF 2.1.1.176 J NOL1 NOP2 sun family protein
HMOKDKBH_00064 9.7e-169
HMOKDKBH_00065 7.5e-143
HMOKDKBH_00066 3.9e-104 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMOKDKBH_00067 1.4e-26
HMOKDKBH_00068 6.7e-145
HMOKDKBH_00069 5.1e-137
HMOKDKBH_00070 4.5e-141
HMOKDKBH_00071 9.6e-124 skfE V ATPases associated with a variety of cellular activities
HMOKDKBH_00072 1.4e-60 yvoA_1 K Transcriptional regulator, GntR family
HMOKDKBH_00073 1.7e-240 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMOKDKBH_00074 1.4e-152 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HMOKDKBH_00075 3.5e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
HMOKDKBH_00076 4.8e-81 mutT 3.6.1.55 F NUDIX domain
HMOKDKBH_00077 1.4e-127 S Peptidase family M23
HMOKDKBH_00078 9.9e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMOKDKBH_00079 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HMOKDKBH_00080 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HMOKDKBH_00081 4.6e-179 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HMOKDKBH_00082 2.9e-134 recO L Involved in DNA repair and RecF pathway recombination
HMOKDKBH_00083 2.1e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMOKDKBH_00084 2.2e-93 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMOKDKBH_00085 1.1e-175 phoH T phosphate starvation-inducible protein PhoH
HMOKDKBH_00086 3.5e-71 yqeY S YqeY-like protein
HMOKDKBH_00087 2e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HMOKDKBH_00088 1.2e-154 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HMOKDKBH_00089 1.5e-18 S CRISPR-associated protein (Cas_Csn2)
HMOKDKBH_00090 1.3e-116 S Peptidase family M23
HMOKDKBH_00091 1.8e-104 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMOKDKBH_00093 4.6e-160 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMOKDKBH_00094 9.4e-118
HMOKDKBH_00095 2.8e-157 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HMOKDKBH_00096 6.6e-221 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
HMOKDKBH_00097 2.6e-280 thrC 4.2.3.1 E Threonine synthase
HMOKDKBH_00098 4.4e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMOKDKBH_00099 9.6e-103 pgm3 5.4.2.11 G Histidine phosphatase superfamily (branch 1)
HMOKDKBH_00100 0.0 L PLD-like domain
HMOKDKBH_00101 4.8e-42 S SnoaL-like domain
HMOKDKBH_00102 5.4e-53 hipB K sequence-specific DNA binding
HMOKDKBH_00103 8e-22 rpiB 5.3.1.6 G Ribose/Galactose Isomerase
HMOKDKBH_00104 3.4e-27
HMOKDKBH_00105 7.8e-52 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_00106 2.6e-275 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_00107 9.4e-124 L Transposase
HMOKDKBH_00108 1.3e-94
HMOKDKBH_00109 3e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMOKDKBH_00110 9e-98
HMOKDKBH_00111 4.9e-108 K LysR substrate binding domain
HMOKDKBH_00112 1e-20
HMOKDKBH_00113 2.3e-215 S Sterol carrier protein domain
HMOKDKBH_00114 9.2e-95 citX 2.4.2.52, 2.7.7.61 HI Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
HMOKDKBH_00115 2e-105 argF 2.1.3.3, 2.7.2.2 E Belongs to the carbamate kinase family
HMOKDKBH_00116 4.3e-66 argF 2.1.3.3, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMOKDKBH_00117 5.7e-233 arcA 3.5.3.6 E Arginine
HMOKDKBH_00118 9e-137 lysR5 K LysR substrate binding domain
HMOKDKBH_00119 0.0 mgtA 3.6.3.2, 3.6.3.6 P Cation transporter/ATPase, N-terminus
HMOKDKBH_00120 1e-48 S Metal binding domain of Ada
HMOKDKBH_00121 2.3e-43 ybhL S Belongs to the BI1 family
HMOKDKBH_00122 1.2e-210 S Bacterial protein of unknown function (DUF871)
HMOKDKBH_00123 3.4e-135 glnQ E ABC transporter, ATP-binding protein
HMOKDKBH_00124 6.7e-290 glnP P ABC transporter permease
HMOKDKBH_00125 4e-121 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HMOKDKBH_00126 5.8e-64 yeaO S Protein of unknown function, DUF488
HMOKDKBH_00127 1.3e-124 terC P Integral membrane protein TerC family
HMOKDKBH_00128 1.3e-57 ogt 2.1.1.63 L 6-O-methylguanine DNA methyltransferase, DNA binding domain
HMOKDKBH_00129 4e-47 S Bacterial PH domain
HMOKDKBH_00130 8.5e-98 S Phage integrase family
HMOKDKBH_00131 3.5e-94 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HMOKDKBH_00132 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HMOKDKBH_00133 1.5e-102 srtA 3.4.22.70 M sortase family
HMOKDKBH_00134 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HMOKDKBH_00135 2.2e-202 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HMOKDKBH_00136 0.0 dnaK O Heat shock 70 kDa protein
HMOKDKBH_00137 8e-68 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMOKDKBH_00138 4.9e-193 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HMOKDKBH_00139 3.2e-175 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HMOKDKBH_00140 1.6e-155 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMOKDKBH_00141 1.1e-59 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMOKDKBH_00142 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMOKDKBH_00143 3.2e-47 rplGA J ribosomal protein
HMOKDKBH_00144 8.8e-47 ylxR K Protein of unknown function (DUF448)
HMOKDKBH_00145 1.4e-196 nusA K Participates in both transcription termination and antitermination
HMOKDKBH_00146 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
HMOKDKBH_00147 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMOKDKBH_00148 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HMOKDKBH_00149 5.7e-196 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HMOKDKBH_00150 8.4e-140 cdsA 2.7.7.41 I Belongs to the CDS family
HMOKDKBH_00151 5.4e-138 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMOKDKBH_00152 5.3e-93 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HMOKDKBH_00153 1.4e-130 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HMOKDKBH_00154 3.1e-184 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMOKDKBH_00155 3.7e-137 rpsB J Belongs to the universal ribosomal protein uS2 family
HMOKDKBH_00156 3e-195 yabB 2.1.1.223 L Methyltransferase small domain
HMOKDKBH_00157 2.9e-116 plsC 2.3.1.51 I Acyltransferase
HMOKDKBH_00158 3.9e-223 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HMOKDKBH_00159 0.0 pepO 3.4.24.71 O Peptidase family M13
HMOKDKBH_00160 0.0 mdlB V ABC transporter
HMOKDKBH_00161 0.0 mdlA V ABC transporter
HMOKDKBH_00162 5.5e-30 yneF S Uncharacterised protein family (UPF0154)
HMOKDKBH_00163 3e-38 ynzC S UPF0291 protein
HMOKDKBH_00164 2e-112 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMOKDKBH_00165 9.8e-146 E GDSL-like Lipase/Acylhydrolase family
HMOKDKBH_00166 5.4e-121 ung2 3.2.2.27 L Uracil-DNA glycosylase
HMOKDKBH_00167 4.6e-213 S SLAP domain
HMOKDKBH_00168 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HMOKDKBH_00169 3.2e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HMOKDKBH_00170 3.4e-94 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMOKDKBH_00171 7.6e-45 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HMOKDKBH_00172 4.9e-228 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMOKDKBH_00173 6e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HMOKDKBH_00174 2.7e-258 yfnA E amino acid
HMOKDKBH_00175 0.0 V FtsX-like permease family
HMOKDKBH_00176 4.1e-133 cysA V ABC transporter, ATP-binding protein
HMOKDKBH_00177 3.4e-23
HMOKDKBH_00179 2.5e-288 pipD E Dipeptidase
HMOKDKBH_00180 3.6e-161 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HMOKDKBH_00181 0.0 smc D Required for chromosome condensation and partitioning
HMOKDKBH_00182 1.9e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HMOKDKBH_00183 2.1e-308 oppA E ABC transporter substrate-binding protein
HMOKDKBH_00184 3.1e-240 oppA E ABC transporter substrate-binding protein
HMOKDKBH_00185 2.8e-134 S Uncharacterised protein family (UPF0236)
HMOKDKBH_00186 9.7e-46 oppA E ABC transporter substrate-binding protein
HMOKDKBH_00187 5.6e-132 oppC P Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00188 2.6e-172 oppB P ABC transporter permease
HMOKDKBH_00189 1.5e-170 oppF P Belongs to the ABC transporter superfamily
HMOKDKBH_00190 1.1e-192 oppD P Belongs to the ABC transporter superfamily
HMOKDKBH_00191 4.9e-35 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMOKDKBH_00192 3.7e-182 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HMOKDKBH_00193 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HMOKDKBH_00194 7.6e-305 yloV S DAK2 domain fusion protein YloV
HMOKDKBH_00195 4e-57 asp S Asp23 family, cell envelope-related function
HMOKDKBH_00196 1.4e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HMOKDKBH_00197 1.4e-30
HMOKDKBH_00198 4.1e-124 thiN 2.7.6.2 H thiamine pyrophosphokinase
HMOKDKBH_00199 2.9e-119 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HMOKDKBH_00200 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HMOKDKBH_00201 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HMOKDKBH_00202 1.1e-138 stp 3.1.3.16 T phosphatase
HMOKDKBH_00203 1.6e-244 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMOKDKBH_00204 5.7e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HMOKDKBH_00205 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMOKDKBH_00206 1.1e-33 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HMOKDKBH_00207 2.1e-111 gmk 2.7.4.8, 4.1.1.23 F Essential for recycling GMP and indirectly, cGMP
HMOKDKBH_00208 1.1e-77 6.3.3.2 S ASCH
HMOKDKBH_00209 2.6e-300 recN L May be involved in recombinational repair of damaged DNA
HMOKDKBH_00210 2.3e-153 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HMOKDKBH_00211 1e-159 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMOKDKBH_00212 3.7e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMOKDKBH_00213 2.9e-193 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HMOKDKBH_00214 6.7e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMOKDKBH_00215 1.1e-63 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMOKDKBH_00216 3.4e-71 yqhY S Asp23 family, cell envelope-related function
HMOKDKBH_00217 4.9e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMOKDKBH_00218 1e-196 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMOKDKBH_00219 1.3e-47 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HMOKDKBH_00220 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HMOKDKBH_00221 3.7e-151 S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMOKDKBH_00222 7.8e-255 S Uncharacterized protein conserved in bacteria (DUF2325)
HMOKDKBH_00224 1.6e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HMOKDKBH_00225 4.3e-298 S Predicted membrane protein (DUF2207)
HMOKDKBH_00226 1.2e-155 cinI S Serine hydrolase (FSH1)
HMOKDKBH_00227 1e-205 M Glycosyl hydrolases family 25
HMOKDKBH_00229 8.5e-178 I Carboxylesterase family
HMOKDKBH_00230 1.5e-64 arsC 1.20.4.1 P Belongs to the ArsC family
HMOKDKBH_00231 2.9e-277 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_00232 4.5e-291 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_00233 1.7e-148 S haloacid dehalogenase-like hydrolase
HMOKDKBH_00234 7e-50
HMOKDKBH_00235 1.9e-37
HMOKDKBH_00236 1.2e-63 S Alpha beta hydrolase
HMOKDKBH_00237 3.7e-19 S Alpha beta hydrolase
HMOKDKBH_00238 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HMOKDKBH_00239 2.8e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HMOKDKBH_00240 7.1e-46
HMOKDKBH_00241 3.1e-148 glcU U sugar transport
HMOKDKBH_00242 3.7e-250 lctP C L-lactate permease
HMOKDKBH_00243 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HMOKDKBH_00244 6.4e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMOKDKBH_00245 8.8e-245 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HMOKDKBH_00246 3.6e-182 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HMOKDKBH_00247 7.2e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMOKDKBH_00248 9.1e-167 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HMOKDKBH_00249 1.6e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HMOKDKBH_00250 1.9e-118 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMOKDKBH_00251 1.5e-102 GM NmrA-like family
HMOKDKBH_00253 9.7e-44 clcA P chloride
HMOKDKBH_00254 2.5e-115 L PFAM Integrase catalytic
HMOKDKBH_00255 1.3e-284 lsa S ABC transporter
HMOKDKBH_00256 2.4e-44
HMOKDKBH_00257 1.3e-122 sdaAB 4.3.1.17 E Serine dehydratase beta chain
HMOKDKBH_00258 3.8e-154 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
HMOKDKBH_00259 9.7e-52 S Iron-sulfur cluster assembly protein
HMOKDKBH_00260 6.9e-116 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMOKDKBH_00261 5e-48 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HMOKDKBH_00262 3.7e-243 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HMOKDKBH_00263 1.1e-223 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMOKDKBH_00264 3.3e-275 yjeM E Amino Acid
HMOKDKBH_00265 5.8e-83 S Fic/DOC family
HMOKDKBH_00266 3.1e-278
HMOKDKBH_00267 3.2e-77
HMOKDKBH_00268 2.3e-87 S Protein of unknown function (DUF805)
HMOKDKBH_00269 5.6e-68 O OsmC-like protein
HMOKDKBH_00270 9.4e-209 EGP Major facilitator Superfamily
HMOKDKBH_00271 2.5e-215 sptS 2.7.13.3 T Histidine kinase
HMOKDKBH_00272 6.4e-24 K response regulator
HMOKDKBH_00273 6.4e-71 scrR K Periplasmic binding protein domain
HMOKDKBH_00274 5.5e-36
HMOKDKBH_00275 2e-196 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HMOKDKBH_00276 1.1e-288 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HMOKDKBH_00277 1.1e-220 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HMOKDKBH_00278 0.0 lacZ 3.2.1.23 G -beta-galactosidase
HMOKDKBH_00279 0.0 lacS G Transporter
HMOKDKBH_00280 3.2e-165 lacR K Transcriptional regulator
HMOKDKBH_00281 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HMOKDKBH_00282 3.5e-145 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HMOKDKBH_00283 5.3e-189 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HMOKDKBH_00284 7.6e-163 S Nucleotidyl transferase AbiEii toxin, Type IV TA system
HMOKDKBH_00285 2e-106 K Transcriptional regulator, AbiEi antitoxin
HMOKDKBH_00286 1.2e-188 K Periplasmic binding protein-like domain
HMOKDKBH_00287 5.8e-73 S domain protein
HMOKDKBH_00289 4.9e-251 ade 3.5.4.2 F Adenine deaminase C-terminal domain
HMOKDKBH_00290 3e-145 potD2 P ABC transporter
HMOKDKBH_00291 1.6e-135 potA11 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMOKDKBH_00292 2.2e-108 potC3 E Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00293 1.7e-38 L Transposase
HMOKDKBH_00294 3.6e-88 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMOKDKBH_00295 7.7e-10 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMOKDKBH_00296 2.9e-109 nanE 5.1.3.9 G Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HMOKDKBH_00297 1.7e-36 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HMOKDKBH_00298 1.1e-59 axe1 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HMOKDKBH_00299 1e-220 nanT E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMOKDKBH_00300 1.9e-121 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HMOKDKBH_00301 2.3e-56 G Xylose isomerase domain protein TIM barrel
HMOKDKBH_00302 8.4e-90 nanK GK ROK family
HMOKDKBH_00303 2.9e-122 nanA 4.1.3.3, 4.3.3.7 EM Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate
HMOKDKBH_00304 3.7e-66 K Helix-turn-helix domain, rpiR family
HMOKDKBH_00305 7.1e-263 E ABC transporter, substratebinding protein
HMOKDKBH_00306 9.1e-10 K peptidyl-tyrosine sulfation
HMOKDKBH_00308 1.1e-114 S interspecies interaction between organisms
HMOKDKBH_00309 2.7e-34
HMOKDKBH_00312 1.9e-21
HMOKDKBH_00313 6e-148
HMOKDKBH_00314 6.7e-170
HMOKDKBH_00315 2e-263 glnA 6.3.1.2 E glutamine synthetase
HMOKDKBH_00316 7.6e-225 ynbB 4.4.1.1 P aluminum resistance
HMOKDKBH_00317 1.5e-167 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMOKDKBH_00318 1.5e-65 yqhL P Rhodanese-like protein
HMOKDKBH_00319 9.7e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HMOKDKBH_00320 4e-119 gluP 3.4.21.105 S Rhomboid family
HMOKDKBH_00321 2.7e-97 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMOKDKBH_00322 1.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HMOKDKBH_00323 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HMOKDKBH_00324 0.0 S membrane
HMOKDKBH_00325 5.2e-170 2.7.1.59 G BadF/BadG/BcrA/BcrD ATPase family
HMOKDKBH_00326 1.3e-38 S RelB antitoxin
HMOKDKBH_00327 3.4e-51 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMOKDKBH_00328 6.7e-44 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMOKDKBH_00329 6.7e-139 fhuC 3.6.3.34 HP abc transporter atp-binding protein
HMOKDKBH_00330 9.5e-148 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMOKDKBH_00331 8.7e-159 isdE P Periplasmic binding protein
HMOKDKBH_00332 6.3e-123 M Iron Transport-associated domain
HMOKDKBH_00333 3e-09 isdH M Iron Transport-associated domain
HMOKDKBH_00334 2.2e-89
HMOKDKBH_00335 2.2e-113 S SLAP domain
HMOKDKBH_00336 2.9e-53 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMOKDKBH_00337 5.7e-46 S An automated process has identified a potential problem with this gene model
HMOKDKBH_00338 3e-137 S Protein of unknown function (DUF3100)
HMOKDKBH_00339 4e-245 3.5.1.47 S Peptidase dimerisation domain
HMOKDKBH_00340 5.8e-230 Q Imidazolonepropionase and related amidohydrolases
HMOKDKBH_00341 0.0 oppA E ABC transporter
HMOKDKBH_00342 1.2e-151 S Sucrose-6F-phosphate phosphohydrolase
HMOKDKBH_00343 0.0 mco Q Multicopper oxidase
HMOKDKBH_00344 1.9e-25
HMOKDKBH_00345 1.9e-158 metQ1 P Belongs to the nlpA lipoprotein family
HMOKDKBH_00346 4.3e-169 ldh 1.1.1.27 C lactate/malate dehydrogenase, alpha/beta C-terminal domain
HMOKDKBH_00347 2.4e-62 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMOKDKBH_00348 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMOKDKBH_00349 7.1e-200 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMOKDKBH_00350 1.9e-89 ydiM G Major facilitator superfamily
HMOKDKBH_00351 8.5e-133 cobB K SIR2 family
HMOKDKBH_00352 8.1e-91 cjaA ET ABC transporter substrate-binding protein
HMOKDKBH_00353 3e-53 cjaA ET ABC transporter substrate-binding protein
HMOKDKBH_00354 1.8e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMOKDKBH_00355 2e-110 P ABC transporter permease
HMOKDKBH_00356 9.6e-110 papP P ABC transporter, permease protein
HMOKDKBH_00358 8.8e-62 yodB K Transcriptional regulator, HxlR family
HMOKDKBH_00359 5e-134 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMOKDKBH_00360 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HMOKDKBH_00361 2.2e-163 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HMOKDKBH_00362 1.5e-72 S Aminoacyl-tRNA editing domain
HMOKDKBH_00363 1.2e-54 S Abi-like protein
HMOKDKBH_00364 8e-224 S SLAP domain
HMOKDKBH_00365 3.9e-128 S CAAX protease self-immunity
HMOKDKBH_00366 1.3e-277 arlS 2.7.13.3 T Histidine kinase
HMOKDKBH_00367 1.2e-126 K response regulator
HMOKDKBH_00368 4.7e-97 yceD S Uncharacterized ACR, COG1399
HMOKDKBH_00369 1.7e-215 ylbM S Belongs to the UPF0348 family
HMOKDKBH_00370 5.3e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HMOKDKBH_00371 4.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HMOKDKBH_00372 4.4e-123 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMOKDKBH_00373 4.4e-200 yqeH S Ribosome biogenesis GTPase YqeH
HMOKDKBH_00374 4.2e-84 yqeG S HAD phosphatase, family IIIA
HMOKDKBH_00375 9.2e-201 tnpB L Putative transposase DNA-binding domain
HMOKDKBH_00376 6.9e-152 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HMOKDKBH_00377 3e-57 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMOKDKBH_00378 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HMOKDKBH_00379 3.2e-72 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HMOKDKBH_00380 4e-98 rihB 3.2.2.1 F Nucleoside
HMOKDKBH_00381 3.7e-101 potB E Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00382 3.9e-23 S domain protein
HMOKDKBH_00383 1.7e-168 V ABC transporter
HMOKDKBH_00384 7.7e-39 S Protein of unknown function (DUF3021)
HMOKDKBH_00385 4.2e-53 K LytTr DNA-binding domain
HMOKDKBH_00388 3e-107 L Transposase
HMOKDKBH_00389 4.3e-75
HMOKDKBH_00390 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMOKDKBH_00391 1.3e-168 dnaI L Primosomal protein DnaI
HMOKDKBH_00392 5.1e-251 dnaB L Replication initiation and membrane attachment
HMOKDKBH_00393 3.5e-82 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMOKDKBH_00394 1.3e-105 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HMOKDKBH_00395 4.2e-155 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HMOKDKBH_00396 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMOKDKBH_00397 3.5e-25 qmcA O prohibitin homologues
HMOKDKBH_00398 7.4e-105 qmcA O prohibitin homologues
HMOKDKBH_00399 8e-51 L RelB antitoxin
HMOKDKBH_00400 4.5e-188 S Bacteriocin helveticin-J
HMOKDKBH_00401 5.2e-09 L Transposase
HMOKDKBH_00402 2.7e-141 L An automated process has identified a potential problem with this gene model
HMOKDKBH_00403 4.4e-283 M Peptidase family M1 domain
HMOKDKBH_00404 1.8e-176 S SLAP domain
HMOKDKBH_00405 6.9e-218 mepA V MATE efflux family protein
HMOKDKBH_00406 9.7e-247 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HMOKDKBH_00407 1.4e-122 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HMOKDKBH_00408 2.8e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HMOKDKBH_00410 3.3e-126 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HMOKDKBH_00411 6.5e-221 ecsB U ABC transporter
HMOKDKBH_00412 5.7e-135 ecsA V ABC transporter, ATP-binding protein
HMOKDKBH_00413 8.3e-78 hit FG Scavenger mRNA decapping enzyme C-term binding
HMOKDKBH_00414 3.9e-25
HMOKDKBH_00415 4.3e-153 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HMOKDKBH_00416 1.9e-72 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HMOKDKBH_00417 5.3e-226
HMOKDKBH_00418 7.9e-29
HMOKDKBH_00419 2.4e-51 S Domain of unknown function DUF1829
HMOKDKBH_00420 2.9e-23
HMOKDKBH_00421 1.9e-186 cbf S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMOKDKBH_00422 0.0 L AAA domain
HMOKDKBH_00423 1e-226 yhaO L Ser Thr phosphatase family protein
HMOKDKBH_00424 7.2e-56 yheA S Belongs to the UPF0342 family
HMOKDKBH_00425 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HMOKDKBH_00426 4.2e-150 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMOKDKBH_00427 0.0 ppsA 2.7.9.2 H Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate
HMOKDKBH_00428 7.5e-103 G Phosphoglycerate mutase family
HMOKDKBH_00429 7.8e-140 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HMOKDKBH_00430 7.4e-128 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
HMOKDKBH_00431 4.5e-192 I transferase activity, transferring acyl groups other than amino-acyl groups
HMOKDKBH_00432 5.6e-179 S PFAM Archaeal ATPase
HMOKDKBH_00433 2.4e-128 S cog cog1373
HMOKDKBH_00434 1.4e-109 yniG EGP Major facilitator Superfamily
HMOKDKBH_00435 5.4e-237 L transposase, IS605 OrfB family
HMOKDKBH_00436 4.5e-76 yniG EGP Major facilitator Superfamily
HMOKDKBH_00437 1.1e-34
HMOKDKBH_00440 1.3e-42
HMOKDKBH_00441 1.9e-75 M LysM domain
HMOKDKBH_00443 1.3e-161 L PFAM transposase, IS4 family protein
HMOKDKBH_00444 9.3e-86
HMOKDKBH_00445 2.5e-283 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMOKDKBH_00446 7.7e-182 S Alpha/beta hydrolase of unknown function (DUF915)
HMOKDKBH_00447 3e-147 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMOKDKBH_00449 1.1e-71 2.5.1.74 H UbiA prenyltransferase family
HMOKDKBH_00450 7.7e-26
HMOKDKBH_00451 5.7e-84 S PFAM Archaeal ATPase
HMOKDKBH_00452 1.9e-84 S PFAM Archaeal ATPase
HMOKDKBH_00453 4.6e-171 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
HMOKDKBH_00454 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HMOKDKBH_00455 6.7e-98 M ErfK YbiS YcfS YnhG
HMOKDKBH_00456 2.8e-154 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HMOKDKBH_00457 1.3e-240 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HMOKDKBH_00459 4.7e-46 pspC KT PspC domain
HMOKDKBH_00460 3.3e-237 L COG2963 Transposase and inactivated derivatives
HMOKDKBH_00461 1.1e-282 phoR 2.7.13.3 T Histidine kinase
HMOKDKBH_00462 4.3e-121 T Transcriptional regulatory protein, C terminal
HMOKDKBH_00463 1.4e-105 phoU P Plays a role in the regulation of phosphate uptake
HMOKDKBH_00464 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMOKDKBH_00465 1.2e-152 pstA P Phosphate transport system permease protein PstA
HMOKDKBH_00466 1.1e-159 pstC P probably responsible for the translocation of the substrate across the membrane
HMOKDKBH_00467 4.2e-145 pstS P Phosphate
HMOKDKBH_00468 1.3e-30
HMOKDKBH_00469 6.3e-192 oppA E ABC transporter, substratebinding protein
HMOKDKBH_00470 4.7e-275 ytgP S Polysaccharide biosynthesis protein
HMOKDKBH_00471 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMOKDKBH_00472 1.1e-121 3.6.1.27 I Acid phosphatase homologues
HMOKDKBH_00473 2.8e-168 K LysR substrate binding domain
HMOKDKBH_00474 2.3e-84 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMOKDKBH_00475 6.2e-43 1.3.5.4 C FAD binding domain
HMOKDKBH_00476 2.4e-231 ndh 1.6.99.3 C NADH dehydrogenase
HMOKDKBH_00477 1.1e-161 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HMOKDKBH_00478 2.8e-120 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HMOKDKBH_00479 2.2e-128 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HMOKDKBH_00480 1.9e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMOKDKBH_00481 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HMOKDKBH_00482 8.2e-177 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HMOKDKBH_00483 7.9e-238 cydA 1.10.3.14 C ubiquinol oxidase
HMOKDKBH_00484 1.5e-22 cydA 1.10.3.14 C ubiquinol oxidase
HMOKDKBH_00485 3.7e-130 ybbH_2 K rpiR family
HMOKDKBH_00486 3.4e-195 S Bacterial protein of unknown function (DUF871)
HMOKDKBH_00487 1.9e-211 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMOKDKBH_00488 1.8e-119 S Putative esterase
HMOKDKBH_00489 3.6e-120 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HMOKDKBH_00490 1.3e-79 ybbH_2 K Helix-turn-helix domain, rpiR family
HMOKDKBH_00492 5.5e-259 qacA EGP Major facilitator Superfamily
HMOKDKBH_00493 1.7e-221 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMOKDKBH_00496 6.2e-165 psaA P Belongs to the bacterial solute-binding protein 9 family
HMOKDKBH_00497 2.5e-35 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMOKDKBH_00498 5.9e-24
HMOKDKBH_00499 4.5e-68 M Glycosyl hydrolases family 25
HMOKDKBH_00500 2.1e-135 UW LPXTG-motif cell wall anchor domain protein
HMOKDKBH_00501 1.3e-161 UW LPXTG-motif cell wall anchor domain protein
HMOKDKBH_00502 3.3e-45 UW LPXTG-motif cell wall anchor domain protein
HMOKDKBH_00503 9.1e-10 UW LPXTG-motif cell wall anchor domain protein
HMOKDKBH_00504 1.3e-248 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMOKDKBH_00505 7.5e-100 J Acetyltransferase (GNAT) domain
HMOKDKBH_00506 1.4e-110 yjbF S SNARE associated Golgi protein
HMOKDKBH_00507 6e-151 I alpha/beta hydrolase fold
HMOKDKBH_00508 1.4e-156 hipB K Helix-turn-helix
HMOKDKBH_00509 1.4e-15 S cog cog1373
HMOKDKBH_00510 1e-30 S cog cog1373
HMOKDKBH_00511 7.6e-91 F Nucleoside 2-deoxyribosyltransferase
HMOKDKBH_00512 3.3e-261 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HMOKDKBH_00513 1.8e-226 L COG3547 Transposase and inactivated derivatives
HMOKDKBH_00514 1.8e-163
HMOKDKBH_00515 7.8e-26 K Acetyltransferase (GNAT) domain
HMOKDKBH_00517 0.0 ydgH S MMPL family
HMOKDKBH_00518 6.6e-99 yobS K Bacterial regulatory proteins, tetR family
HMOKDKBH_00519 4.4e-140 ypuA S Protein of unknown function (DUF1002)
HMOKDKBH_00520 3.7e-156 epsV 2.7.8.12 S glycosyl transferase family 2
HMOKDKBH_00521 7.3e-126 S Alpha/beta hydrolase family
HMOKDKBH_00522 3.3e-148 3.5.2.6 V Beta-lactamase enzyme family
HMOKDKBH_00523 1.8e-154 corA P CorA-like Mg2+ transporter protein
HMOKDKBH_00524 6.7e-240 G Bacterial extracellular solute-binding protein
HMOKDKBH_00525 9.2e-258 YSH1 S Zn-dependent metallo-hydrolase RNA specificity domain
HMOKDKBH_00526 1.8e-145 gtsC P Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00527 1.6e-157 gtsB P ABC-type sugar transport systems, permease components
HMOKDKBH_00528 1.9e-203 malK P ATPases associated with a variety of cellular activities
HMOKDKBH_00529 1.3e-281 pipD E Dipeptidase
HMOKDKBH_00530 1.9e-158 endA F DNA RNA non-specific endonuclease
HMOKDKBH_00531 8e-182 dnaQ 2.7.7.7 L EXOIII
HMOKDKBH_00532 9e-158 K NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMOKDKBH_00533 3e-116 yviA S Protein of unknown function (DUF421)
HMOKDKBH_00534 1.1e-56 S Protein of unknown function (DUF3290)
HMOKDKBH_00536 3.8e-139 pnuC H nicotinamide mononucleotide transporter
HMOKDKBH_00537 4e-08
HMOKDKBH_00538 6.6e-56
HMOKDKBH_00539 2.7e-57
HMOKDKBH_00540 1.6e-11
HMOKDKBH_00541 8.1e-126 S PAS domain
HMOKDKBH_00542 2.9e-277 V ABC transporter transmembrane region
HMOKDKBH_00543 2.1e-179 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HMOKDKBH_00544 3.1e-130 T Transcriptional regulatory protein, C terminal
HMOKDKBH_00545 5.2e-187 T GHKL domain
HMOKDKBH_00546 3.4e-76 S Peptidase propeptide and YPEB domain
HMOKDKBH_00547 2.5e-72 S Peptidase propeptide and YPEB domain
HMOKDKBH_00548 4.7e-83 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMOKDKBH_00549 3.8e-65 yybA 2.3.1.57 K Transcriptional regulator
HMOKDKBH_00550 7e-68 V ABC transporter transmembrane region
HMOKDKBH_00551 9e-161 V ABC transporter transmembrane region
HMOKDKBH_00552 2.3e-309 oppA3 E ABC transporter, substratebinding protein
HMOKDKBH_00553 4.9e-61 ypaA S Protein of unknown function (DUF1304)
HMOKDKBH_00554 2.1e-28 S Peptidase propeptide and YPEB domain
HMOKDKBH_00555 7.1e-237 L transposase, IS605 OrfB family
HMOKDKBH_00556 8.8e-58 S Peptidase propeptide and YPEB domain
HMOKDKBH_00557 1.3e-102 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMOKDKBH_00558 2.5e-169 coaA 2.7.1.33 F Pantothenic acid kinase
HMOKDKBH_00559 7.1e-98 E GDSL-like Lipase/Acylhydrolase
HMOKDKBH_00560 7.5e-74 yjcF S Acetyltransferase (GNAT) domain
HMOKDKBH_00561 1.6e-143 aatB ET ABC transporter substrate-binding protein
HMOKDKBH_00562 1e-105 glnQ 3.6.3.21 E ABC transporter
HMOKDKBH_00563 2.8e-106 glnP P ABC transporter permease
HMOKDKBH_00564 0.0 helD 3.6.4.12 L DNA helicase
HMOKDKBH_00565 2.7e-124 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HMOKDKBH_00566 1.4e-126 pgm3 G Phosphoglycerate mutase family
HMOKDKBH_00567 1.2e-241 S response to antibiotic
HMOKDKBH_00568 4.9e-125
HMOKDKBH_00569 0.0 3.6.3.8 P P-type ATPase
HMOKDKBH_00570 8.7e-66 2.7.1.191 G PTS system fructose IIA component
HMOKDKBH_00571 4.4e-43
HMOKDKBH_00572 1.5e-186 ansA 3.5.1.1 EJ L-asparaginase, type I
HMOKDKBH_00573 1.8e-136 glvR K Helix-turn-helix domain, rpiR family
HMOKDKBH_00574 2.7e-268 aglB 3.2.1.122, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase C-terminal domain
HMOKDKBH_00575 4e-153
HMOKDKBH_00576 8.6e-24
HMOKDKBH_00577 3.2e-87 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMOKDKBH_00578 2.1e-105 3.2.2.20 K acetyltransferase
HMOKDKBH_00581 1.6e-72 S Membrane protein involved in the export of O-antigen and teichoic acid
HMOKDKBH_00582 7.4e-106 S Bacterial protein of unknown function (DUF871)
HMOKDKBH_00583 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMOKDKBH_00584 2.7e-73 L Transposase DDE domain
HMOKDKBH_00585 3e-54 L An automated process has identified a potential problem with this gene model
HMOKDKBH_00587 4.7e-38
HMOKDKBH_00588 3.3e-183 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMOKDKBH_00589 8.4e-125 luxT K Bacterial regulatory proteins, tetR family
HMOKDKBH_00590 1.1e-134
HMOKDKBH_00591 1.3e-258 glnPH2 P ABC transporter permease
HMOKDKBH_00592 2.6e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMOKDKBH_00593 6.4e-224 S Cysteine-rich secretory protein family
HMOKDKBH_00594 1.2e-205 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HMOKDKBH_00595 1.4e-112
HMOKDKBH_00596 6.3e-202 yibE S overlaps another CDS with the same product name
HMOKDKBH_00597 4.9e-129 yibF S overlaps another CDS with the same product name
HMOKDKBH_00598 2.5e-144 I alpha/beta hydrolase fold
HMOKDKBH_00599 0.0 G Belongs to the glycosyl hydrolase 31 family
HMOKDKBH_00600 4.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HMOKDKBH_00601 1.5e-110 rfbP M Bacterial sugar transferase
HMOKDKBH_00602 3.1e-144 ywqE 3.1.3.48 GM PHP domain protein
HMOKDKBH_00603 3e-118 ywqD 2.7.10.1 D Capsular exopolysaccharide family
HMOKDKBH_00604 1.4e-148 epsB M biosynthesis protein
HMOKDKBH_00605 1.5e-178 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMOKDKBH_00606 1.3e-47 yoeB S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMOKDKBH_00607 1.3e-41 relB L RelB antitoxin
HMOKDKBH_00609 2e-217 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMOKDKBH_00610 4.6e-175 S Cysteine-rich secretory protein family
HMOKDKBH_00612 1.6e-41
HMOKDKBH_00613 2.6e-118 M NlpC/P60 family
HMOKDKBH_00614 1.4e-136 M NlpC P60 family protein
HMOKDKBH_00615 5e-88 M NlpC/P60 family
HMOKDKBH_00616 2.2e-88 gmk2 2.7.4.8 F Guanylate kinase homologues.
HMOKDKBH_00617 3.9e-42
HMOKDKBH_00618 2.9e-279 S O-antigen ligase like membrane protein
HMOKDKBH_00619 3.3e-112
HMOKDKBH_00620 4.7e-221 tnpB L Putative transposase DNA-binding domain
HMOKDKBH_00621 5.5e-77 nrdI F NrdI Flavodoxin like
HMOKDKBH_00622 9.9e-177 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMOKDKBH_00623 2.5e-68
HMOKDKBH_00624 9.1e-112 yvpB S Peptidase_C39 like family
HMOKDKBH_00625 1.1e-83 S Threonine/Serine exporter, ThrE
HMOKDKBH_00626 2.4e-136 thrE S Putative threonine/serine exporter
HMOKDKBH_00627 8.9e-292 S ABC transporter
HMOKDKBH_00628 8.3e-58
HMOKDKBH_00629 5e-72 rimL J Acetyltransferase (GNAT) domain
HMOKDKBH_00630 1.4e-34
HMOKDKBH_00631 1.2e-30
HMOKDKBH_00632 1.8e-111 S Protein of unknown function (DUF554)
HMOKDKBH_00633 8.7e-197 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMOKDKBH_00634 0.0 pepF E oligoendopeptidase F
HMOKDKBH_00635 2.9e-31
HMOKDKBH_00636 1.3e-69 doc S Prophage maintenance system killer protein
HMOKDKBH_00639 4.6e-27 S Enterocin A Immunity
HMOKDKBH_00640 1.7e-22 blpT
HMOKDKBH_00642 1.6e-25 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00643 1.2e-11
HMOKDKBH_00644 1.5e-216 2.1.1.14 E methionine synthase, vitamin-B12 independent
HMOKDKBH_00645 6.7e-89 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HMOKDKBH_00646 2e-264 lctP C L-lactate permease
HMOKDKBH_00647 5e-129 znuB U ABC 3 transport family
HMOKDKBH_00648 1.6e-117 fhuC P ABC transporter
HMOKDKBH_00649 1.6e-147 psaA P Belongs to the bacterial solute-binding protein 9 family
HMOKDKBH_00650 5.4e-41 K helix_turn_helix, Arsenical Resistance Operon Repressor
HMOKDKBH_00651 0.0 fruA 2.7.1.202, 2.7.1.204 GT Phosphotransferase System
HMOKDKBH_00652 2.2e-168 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
HMOKDKBH_00653 1.8e-136 fruR K DeoR C terminal sensor domain
HMOKDKBH_00654 1.8e-218 natB CP ABC-2 family transporter protein
HMOKDKBH_00655 1.1e-164 natA S ABC transporter, ATP-binding protein
HMOKDKBH_00656 1.7e-67
HMOKDKBH_00657 2e-23
HMOKDKBH_00658 8.2e-31 yozG K Transcriptional regulator
HMOKDKBH_00659 3.7e-83
HMOKDKBH_00660 3e-21
HMOKDKBH_00664 2.2e-129 blpT
HMOKDKBH_00665 6.1e-269 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMOKDKBH_00666 1.2e-127 K LytTr DNA-binding domain
HMOKDKBH_00667 1.6e-132 2.7.13.3 T GHKL domain
HMOKDKBH_00668 1.2e-16
HMOKDKBH_00669 2.1e-255 S Archaea bacterial proteins of unknown function
HMOKDKBH_00670 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HMOKDKBH_00671 3e-270 glcD2 1.1.3.15 C FAD linked oxidases, C-terminal domain
HMOKDKBH_00672 1e-24
HMOKDKBH_00673 9.5e-26
HMOKDKBH_00674 2.5e-33
HMOKDKBH_00675 1.4e-53 S Enterocin A Immunity
HMOKDKBH_00676 8e-145 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HMOKDKBH_00677 5.5e-305 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMOKDKBH_00678 6.6e-207 hpk31 2.7.13.3 T His Kinase A (phospho-acceptor) domain
HMOKDKBH_00679 9.6e-121 K response regulator
HMOKDKBH_00681 1.2e-302 V ABC transporter
HMOKDKBH_00682 5.7e-27 V ABC transporter
HMOKDKBH_00683 4.2e-144 V ABC transporter, ATP-binding protein
HMOKDKBH_00684 1.2e-145 V ABC transporter, ATP-binding protein
HMOKDKBH_00685 3.8e-137 XK27_01040 S Protein of unknown function (DUF1129)
HMOKDKBH_00686 3.6e-202 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HMOKDKBH_00687 9.6e-45 yyzM S Bacterial protein of unknown function (DUF951)
HMOKDKBH_00688 8.5e-154 spo0J K Belongs to the ParB family
HMOKDKBH_00689 3.4e-138 soj D Sporulation initiation inhibitor
HMOKDKBH_00690 5e-148 noc K Belongs to the ParB family
HMOKDKBH_00691 1.2e-129 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HMOKDKBH_00692 3e-53 cvpA S Colicin V production protein
HMOKDKBH_00694 2.5e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HMOKDKBH_00695 6e-151 3.1.3.48 T Tyrosine phosphatase family
HMOKDKBH_00696 2e-97 azr 1.5.1.36 S NADPH-dependent FMN reductase
HMOKDKBH_00697 6.4e-96 nqr 1.5.1.36 S NADPH-dependent FMN reductase
HMOKDKBH_00698 2.4e-110 K WHG domain
HMOKDKBH_00699 3e-37
HMOKDKBH_00700 1.3e-273 pipD E Dipeptidase
HMOKDKBH_00701 1.5e-102 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HMOKDKBH_00702 3.3e-176 hrtB V ABC transporter permease
HMOKDKBH_00703 3.2e-92 ygfC K Bacterial regulatory proteins, tetR family
HMOKDKBH_00704 3.5e-111 G phosphoglycerate mutase
HMOKDKBH_00705 4.1e-141 aroD S Alpha/beta hydrolase family
HMOKDKBH_00706 2.2e-142 S Belongs to the UPF0246 family
HMOKDKBH_00707 9e-121
HMOKDKBH_00708 1.9e-157 2.7.7.12 C Domain of unknown function (DUF4931)
HMOKDKBH_00709 1.5e-185 S Putative peptidoglycan binding domain
HMOKDKBH_00710 4e-16
HMOKDKBH_00711 1.4e-93 liaI S membrane
HMOKDKBH_00712 6.6e-70 XK27_02470 K LytTr DNA-binding domain
HMOKDKBH_00713 1.2e-18 S Sugar efflux transporter for intercellular exchange
HMOKDKBH_00714 1.3e-250 dtpT U amino acid peptide transporter
HMOKDKBH_00715 0.0 pepN 3.4.11.2 E aminopeptidase
HMOKDKBH_00716 2.8e-47 lysM M LysM domain
HMOKDKBH_00717 1.3e-174
HMOKDKBH_00718 1.7e-152 mdtG EGP Major facilitator Superfamily
HMOKDKBH_00719 6.9e-47 mdtG EGP Major facilitator Superfamily
HMOKDKBH_00720 4.6e-88 ymdB S Macro domain protein
HMOKDKBH_00722 4.8e-28
HMOKDKBH_00725 4.3e-67 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00726 3.3e-147 malG P ABC transporter permease
HMOKDKBH_00727 1.1e-250 malF P Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00728 1.3e-213 malE G Bacterial extracellular solute-binding protein
HMOKDKBH_00729 6.8e-209 msmX P Belongs to the ABC transporter superfamily
HMOKDKBH_00730 9e-116 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HMOKDKBH_00731 0.0 map2 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HMOKDKBH_00732 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Belongs to the glycosyl hydrolase 13 family
HMOKDKBH_00733 0.0 malL 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain
HMOKDKBH_00734 0.0 fhaB M Rib/alpha-like repeat
HMOKDKBH_00735 8.2e-179 yvdE K helix_turn _helix lactose operon repressor
HMOKDKBH_00736 4.1e-36 ptp2 3.1.3.48 T Tyrosine phosphatase family
HMOKDKBH_00737 5.4e-13
HMOKDKBH_00738 4.1e-101 ptp2 3.1.3.48 T Tyrosine phosphatase family
HMOKDKBH_00739 5.1e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HMOKDKBH_00740 1.5e-144 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HMOKDKBH_00741 1.7e-184 G Transmembrane secretion effector
HMOKDKBH_00742 6.1e-136 V ABC transporter transmembrane region
HMOKDKBH_00743 2.9e-224 L transposase, IS605 OrfB family
HMOKDKBH_00744 1.1e-75 V ABC transporter transmembrane region
HMOKDKBH_00745 6.5e-64 L RelB antitoxin
HMOKDKBH_00746 2.1e-131 cobQ S glutamine amidotransferase
HMOKDKBH_00747 1.8e-81 M NlpC/P60 family
HMOKDKBH_00750 2.6e-155
HMOKDKBH_00751 7.8e-38
HMOKDKBH_00752 2e-32
HMOKDKBH_00753 6.2e-163 EG EamA-like transporter family
HMOKDKBH_00754 5e-165 EG EamA-like transporter family
HMOKDKBH_00755 1.2e-139 yicL EG EamA-like transporter family
HMOKDKBH_00756 4.3e-107
HMOKDKBH_00757 1.1e-110
HMOKDKBH_00758 5.8e-186 XK27_05540 S DUF218 domain
HMOKDKBH_00759 9.3e-264 yheS_2 S ATPases associated with a variety of cellular activities
HMOKDKBH_00760 4.7e-85
HMOKDKBH_00761 3.9e-57
HMOKDKBH_00762 4.7e-25 S Protein conserved in bacteria
HMOKDKBH_00763 1.3e-54 S protein encoded in hypervariable junctions of pilus gene clusters
HMOKDKBH_00764 7.7e-29 hicA S HicA toxin of bacterial toxin-antitoxin,
HMOKDKBH_00765 1.1e-74 L Transposase
HMOKDKBH_00766 6.2e-246 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMOKDKBH_00767 6.4e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMOKDKBH_00768 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMOKDKBH_00771 3.9e-206 4.2.1.126 S Bacterial protein of unknown function (DUF871)
HMOKDKBH_00772 3.2e-189 asnA 6.3.1.1 F aspartate--ammonia ligase
HMOKDKBH_00773 1.8e-230 steT_1 E amino acid
HMOKDKBH_00774 2.2e-139 puuD S peptidase C26
HMOKDKBH_00776 2.4e-172 V HNH endonuclease
HMOKDKBH_00777 6.4e-135 S PFAM Archaeal ATPase
HMOKDKBH_00778 9.2e-248 yifK E Amino acid permease
HMOKDKBH_00779 9.7e-234 cycA E Amino acid permease
HMOKDKBH_00780 4.3e-115 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMOKDKBH_00781 0.0 clpE O AAA domain (Cdc48 subfamily)
HMOKDKBH_00782 2.2e-165 S Alpha/beta hydrolase of unknown function (DUF915)
HMOKDKBH_00783 2.2e-238 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_00784 5.1e-125 XK27_06785 V ABC transporter, ATP-binding protein
HMOKDKBH_00785 0.0 XK27_06780 V ABC transporter permease
HMOKDKBH_00786 1.9e-36
HMOKDKBH_00787 7.9e-291 ytgP S Polysaccharide biosynthesis protein
HMOKDKBH_00788 2.7e-137 lysA2 M Glycosyl hydrolases family 25
HMOKDKBH_00789 2.3e-133 S Protein of unknown function (DUF975)
HMOKDKBH_00790 7.6e-177 pbpX2 V Beta-lactamase
HMOKDKBH_00791 7.3e-247 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HMOKDKBH_00792 1.7e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMOKDKBH_00793 1.9e-236 dltB M MBOAT, membrane-bound O-acyltransferase family
HMOKDKBH_00794 2.1e-285 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HMOKDKBH_00795 1.2e-18 S D-Ala-teichoic acid biosynthesis protein
HMOKDKBH_00796 4.1e-44
HMOKDKBH_00797 1e-207 ywhK S Membrane
HMOKDKBH_00798 1.5e-80 ykuL S (CBS) domain
HMOKDKBH_00799 0.0 cadA P P-type ATPase
HMOKDKBH_00800 2.8e-205 napA P Sodium/hydrogen exchanger family
HMOKDKBH_00801 1.9e-47 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HMOKDKBH_00802 2.3e-41 S YoeB-like toxin of bacterial type II toxin-antitoxin system
HMOKDKBH_00803 4.1e-276 V ABC transporter transmembrane region
HMOKDKBH_00804 2.6e-155 mutR K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00805 5.4e-51
HMOKDKBH_00806 4.2e-154 EGP Major facilitator Superfamily
HMOKDKBH_00807 3e-111 ropB K Transcriptional regulator
HMOKDKBH_00808 2.7e-120 S CAAX protease self-immunity
HMOKDKBH_00809 1.6e-194 S DUF218 domain
HMOKDKBH_00810 0.0 macB_3 V ABC transporter, ATP-binding protein
HMOKDKBH_00811 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMOKDKBH_00812 2.8e-100 S ECF transporter, substrate-specific component
HMOKDKBH_00813 2.9e-25 tcsA S ABC transporter substrate-binding protein PnrA-like
HMOKDKBH_00814 5.4e-161 tcsA S ABC transporter substrate-binding protein PnrA-like
HMOKDKBH_00815 6.9e-181 tcsA S ABC transporter substrate-binding protein PnrA-like
HMOKDKBH_00816 1.3e-282 xylG 3.6.3.17 S ABC transporter
HMOKDKBH_00817 1.9e-198 yufP S Belongs to the binding-protein-dependent transport system permease family
HMOKDKBH_00818 2.2e-171 yufQ S Belongs to the binding-protein-dependent transport system permease family
HMOKDKBH_00819 3.7e-159 yeaE S Aldo/keto reductase family
HMOKDKBH_00820 2.1e-134 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HMOKDKBH_00821 8.5e-119 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMOKDKBH_00822 9.3e-124 dgk 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HMOKDKBH_00823 9.4e-72
HMOKDKBH_00824 8.2e-140 cof S haloacid dehalogenase-like hydrolase
HMOKDKBH_00825 8.2e-230 pbuG S permease
HMOKDKBH_00826 2.1e-76 S ABC-2 family transporter protein
HMOKDKBH_00827 4.7e-60 S ABC-2 family transporter protein
HMOKDKBH_00828 2.4e-92 V ABC transporter, ATP-binding protein
HMOKDKBH_00829 2.5e-119 K helix_turn_helix, mercury resistance
HMOKDKBH_00830 7.5e-231 pbuG S permease
HMOKDKBH_00831 2.5e-40 relB L Addiction module antitoxin, RelB DinJ family
HMOKDKBH_00832 3.1e-16 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMOKDKBH_00833 1.8e-48 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
HMOKDKBH_00835 1.9e-83 K Transcriptional regulator
HMOKDKBH_00836 6.1e-61 K Transcriptional regulator
HMOKDKBH_00837 2e-225 S cog cog1373
HMOKDKBH_00838 9.7e-146 S haloacid dehalogenase-like hydrolase
HMOKDKBH_00839 2.5e-226 pbuG S permease
HMOKDKBH_00840 1.7e-60 L Transposase
HMOKDKBH_00841 1.4e-37 S Putative adhesin
HMOKDKBH_00842 2.6e-151 V ABC transporter transmembrane region
HMOKDKBH_00843 4.6e-138
HMOKDKBH_00844 1.8e-31
HMOKDKBH_00847 2.4e-36
HMOKDKBH_00848 4.6e-56 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMOKDKBH_00849 1.8e-44 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HMOKDKBH_00850 0.0 copA 3.6.3.54 P P-type ATPase
HMOKDKBH_00851 8.2e-114 flpA 4.1.99.16, 4.2.3.22, 4.2.3.75 K helix_turn_helix, cAMP Regulatory protein
HMOKDKBH_00852 1.2e-105
HMOKDKBH_00853 7e-248 EGP Sugar (and other) transporter
HMOKDKBH_00854 1.2e-18
HMOKDKBH_00855 2.8e-210
HMOKDKBH_00856 3.5e-136 S SLAP domain
HMOKDKBH_00857 1.3e-117 S SLAP domain
HMOKDKBH_00858 1.1e-106 S Bacteriocin helveticin-J
HMOKDKBH_00859 1.2e-44
HMOKDKBH_00860 3.7e-58 ps115 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00861 4e-32 E Zn peptidase
HMOKDKBH_00862 3.9e-287 clcA P chloride
HMOKDKBH_00864 6.1e-59 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMOKDKBH_00871 1.3e-17
HMOKDKBH_00872 1.6e-10 relB L Addiction module antitoxin, RelB DinJ family
HMOKDKBH_00880 2.1e-188 L COG2826 Transposase and inactivated derivatives, IS30 family
HMOKDKBH_00886 1.6e-22 cll
HMOKDKBH_00891 3.3e-11
HMOKDKBH_00894 2.7e-16 S Domain of Unknown Function with PDB structure (DUF3850)
HMOKDKBH_00897 1.8e-164 L transposase, IS605 OrfB family
HMOKDKBH_00899 8.7e-40 ftsH1 O ATPase family associated with various cellular activities (AAA)
HMOKDKBH_00903 2.8e-13 rnhA 3.1.26.4 L Caulimovirus viroplasmin
HMOKDKBH_00905 3.6e-18
HMOKDKBH_00906 3e-243 L transposase, IS605 OrfB family
HMOKDKBH_00907 1.2e-85 tlpA2 L Transposase IS200 like
HMOKDKBH_00908 4.6e-13
HMOKDKBH_00913 5.2e-08
HMOKDKBH_00914 3e-89 ntd 2.4.2.6 F Nucleoside
HMOKDKBH_00915 8.6e-87 2.7.1.200, 2.7.1.202, 2.7.1.204 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMOKDKBH_00916 7.5e-149 ptp3 3.1.3.48 T Tyrosine phosphatase family
HMOKDKBH_00917 2.2e-82 uspA T universal stress protein
HMOKDKBH_00919 1.2e-161 phnD P Phosphonate ABC transporter
HMOKDKBH_00920 3e-139 phnC 3.6.3.28 P Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HMOKDKBH_00921 1.4e-120 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00922 1.3e-148 phnE 3.6.1.63 P Binding-protein-dependent transport system inner membrane component
HMOKDKBH_00923 1.4e-81 L COG3385 FOG Transposase and inactivated derivatives
HMOKDKBH_00924 1.2e-48 L PFAM transposase, IS4 family protein
HMOKDKBH_00925 5.6e-124 L Transposase
HMOKDKBH_00928 1.2e-12 S Pfam:Phage_TTP_1
HMOKDKBH_00930 2.8e-12 S Bacteriophage HK97-gp10, putative tail-component
HMOKDKBH_00932 5.5e-19 S Phage gp6-like head-tail connector protein
HMOKDKBH_00933 1.1e-56 S Phage capsid family
HMOKDKBH_00934 5.5e-87 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
HMOKDKBH_00935 9.1e-135 S Phage portal protein
HMOKDKBH_00937 9.5e-211 S Phage Terminase
HMOKDKBH_00938 9e-47 S HicB_like antitoxin of bacterial toxin-antitoxin system
HMOKDKBH_00939 3.4e-18 N HicA toxin of bacterial toxin-antitoxin,
HMOKDKBH_00940 1.6e-55 L Phage terminase, small subunit
HMOKDKBH_00941 1.5e-42 S HNH endonuclease
HMOKDKBH_00942 7.7e-18
HMOKDKBH_00945 1.7e-41 S VRR-NUC domain
HMOKDKBH_00951 1.4e-272 S Phage plasmid primase, P4
HMOKDKBH_00952 4.2e-42 S Protein of unknown function (DUF669)
HMOKDKBH_00954 1.2e-151 res L Helicase C-terminal domain protein
HMOKDKBH_00956 1.1e-71 S AAA domain
HMOKDKBH_00962 6.1e-13
HMOKDKBH_00963 1.4e-16
HMOKDKBH_00966 1.6e-27
HMOKDKBH_00967 3.7e-47 K ORF6N domain
HMOKDKBH_00968 8.1e-45 K ORF6N domain
HMOKDKBH_00969 5.2e-17 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00970 9e-19 K Cro/C1-type HTH DNA-binding domain
HMOKDKBH_00971 1.6e-19 S Pfam:Peptidase_M78
HMOKDKBH_00977 2.6e-10
HMOKDKBH_00978 3.6e-44
HMOKDKBH_00981 9.5e-15
HMOKDKBH_00982 2.6e-25
HMOKDKBH_00983 1e-60 T Toxin-antitoxin system, toxin component, MazF family
HMOKDKBH_00984 8.1e-127 xerS L Belongs to the 'phage' integrase family
HMOKDKBH_00985 1.2e-32 sip M LysM domain protein
HMOKDKBH_00986 5.4e-162 KL domain protein
HMOKDKBH_00987 3.1e-30 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMOKDKBH_00989 7.2e-107 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMOKDKBH_00990 9.4e-13 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMOKDKBH_00991 1.7e-10 S regulation of response to stimulus
HMOKDKBH_00993 1.4e-31 S cog cog0433
HMOKDKBH_00994 8.8e-29
HMOKDKBH_00997 6.7e-50 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_00998 3e-270 L Transposase DDE domain
HMOKDKBH_00999 5.8e-185 L COG2826 Transposase and inactivated derivatives, IS30 family
HMOKDKBH_01001 1.7e-174 L COG3385 FOG Transposase and inactivated derivatives
HMOKDKBH_01002 1.6e-105 tag 3.2.2.20 L glycosylase
HMOKDKBH_01003 3.9e-84
HMOKDKBH_01004 1.7e-273 S Calcineurin-like phosphoesterase
HMOKDKBH_01005 0.0 asnB 6.3.5.4 E Asparagine synthase
HMOKDKBH_01006 5.6e-255 yxbA 6.3.1.12 S ATP-grasp enzyme
HMOKDKBH_01007 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
HMOKDKBH_01008 8.7e-141 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HMOKDKBH_01009 5e-102 S Iron-sulfur cluster assembly protein
HMOKDKBH_01010 1.5e-230 XK27_04775 S PAS domain
HMOKDKBH_01011 3e-210 yttB EGP Major facilitator Superfamily
HMOKDKBH_01012 4e-60 L Resolvase, N terminal domain
HMOKDKBH_01013 4.6e-25 dnaQ 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMOKDKBH_01016 2.9e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMOKDKBH_01017 1.5e-86 S N-acetylmuramoyl-L-alanine amidase activity
HMOKDKBH_01018 0.0 pepO 3.4.24.71 O Peptidase family M13
HMOKDKBH_01021 1.2e-10
HMOKDKBH_01022 8.1e-65 K LytTr DNA-binding domain
HMOKDKBH_01023 1.2e-49 S Protein of unknown function (DUF3021)
HMOKDKBH_01030 1.4e-47 S Uncharacterised protein family (UPF0236)
HMOKDKBH_01031 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HMOKDKBH_01032 5.7e-69 rplI J Binds to the 23S rRNA
HMOKDKBH_01033 1.9e-253 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HMOKDKBH_01034 0.0 kup P Transport of potassium into the cell
HMOKDKBH_01035 7.3e-74
HMOKDKBH_01036 2.1e-45 S PFAM Archaeal ATPase
HMOKDKBH_01038 3.7e-58 T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMOKDKBH_01039 5.9e-45
HMOKDKBH_01040 4e-40 S CRISPR-associated protein (Cas_Csn2)
HMOKDKBH_01041 1.1e-39 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMOKDKBH_01042 3e-130 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMOKDKBH_01043 3.7e-92 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMOKDKBH_01044 1.8e-81 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMOKDKBH_01045 4.5e-10
HMOKDKBH_01046 1.1e-18 S Phage uncharacterised protein (Phage_XkdX)
HMOKDKBH_01047 8.1e-08
HMOKDKBH_01049 2e-17
HMOKDKBH_01050 7.7e-30
HMOKDKBH_01052 3.7e-102 L Integrase
HMOKDKBH_01053 3.6e-69 T Toxin-antitoxin system, toxin component, MazF family
HMOKDKBH_01054 1.3e-30
HMOKDKBH_01055 3.8e-115 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HMOKDKBH_01059 2.3e-17
HMOKDKBH_01061 2.9e-06 S Domain of unknown function (DUF2479)
HMOKDKBH_01063 1.7e-33 S phage tail
HMOKDKBH_01064 5.9e-131 S Phage minor structural protein
HMOKDKBH_01067 5.5e-30
HMOKDKBH_01068 4.3e-40 S Protein of unknown function (DUF2922)
HMOKDKBH_01069 5.7e-101 S SLAP domain
HMOKDKBH_01070 6.7e-19 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMOKDKBH_01072 2.1e-144 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMOKDKBH_01073 1.1e-25
HMOKDKBH_01074 1.4e-76 K DNA-templated transcription, initiation
HMOKDKBH_01075 5.3e-41
HMOKDKBH_01077 1.9e-19
HMOKDKBH_01078 2.5e-264 3.6.3.6 P Cation transporter/ATPase, N-terminus
HMOKDKBH_01079 4.4e-35 3.6.3.2, 3.6.3.6 P cation transport ATPase
HMOKDKBH_01080 7.8e-10 3.6.3.2, 3.6.3.6 P cation transport ATPase
HMOKDKBH_01081 3.8e-80 coaA 2.7.1.33 F Pantothenic acid kinase
HMOKDKBH_01082 3.2e-75 S ECF transporter, substrate-specific component
HMOKDKBH_01083 1.5e-54 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMOKDKBH_01084 3.7e-144 gltC_1 3.1.3.48 K LysR substrate binding domain
HMOKDKBH_01085 5.8e-151 2.8.3.1 I Coenzyme A transferase
HMOKDKBH_01086 1.6e-82 2.8.3.1 I Coenzyme A transferase
HMOKDKBH_01087 9.9e-143 L Transposase
HMOKDKBH_01089 1.6e-135 dnaX 2.4.99.16, 2.7.7.7 GH13 M domain protein
HMOKDKBH_01090 6.3e-132 S SLAP domain
HMOKDKBH_01092 1.2e-47 L Transposase, IS116 IS110 IS902 family
HMOKDKBH_01093 2.4e-91 atl 3.2.1.96, 3.5.1.28 GH73 UW LPXTG-motif cell wall anchor domain protein
HMOKDKBH_01094 3.4e-121 infB M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMOKDKBH_01096 4.5e-151 S Membrane protein involved in the export of O-antigen and teichoic acid
HMOKDKBH_01097 9.6e-184 L DDE superfamily endonuclease
HMOKDKBH_01098 3.5e-138 L Transposase
HMOKDKBH_01099 2.9e-98 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HMOKDKBH_01100 2.5e-176 gatC G PTS system sugar-specific permease component
HMOKDKBH_01101 3.8e-21 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_01102 1.9e-35 2.7.1.194, 2.7.1.200, 2.7.1.202, 2.7.1.204 GT Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMOKDKBH_01103 2.2e-114 gatY G Fructose-bisphosphate aldolase class-II
HMOKDKBH_01104 8.5e-62 farR K Helix-turn-helix domain
HMOKDKBH_01106 2.9e-42 S ASCH domain
HMOKDKBH_01107 2.2e-101 1.8.4.10, 1.8.4.8, 2.7.7.4 EH sulfate reduction
HMOKDKBH_01109 2.3e-30
HMOKDKBH_01110 5.4e-111 K Belongs to the N(4) N(6)-methyltransferase family
HMOKDKBH_01111 8.3e-85 L transposase activity
HMOKDKBH_01112 2.1e-214 S Terminase RNAseH like domain
HMOKDKBH_01113 2.9e-216 S Phage portal protein, SPP1 Gp6-like
HMOKDKBH_01114 7.5e-166 S Phage minor capsid protein 2
HMOKDKBH_01116 1e-36 S Phage minor structural protein GP20
HMOKDKBH_01117 4.6e-154 gpG
HMOKDKBH_01118 2.4e-44
HMOKDKBH_01119 1.6e-39 S Minor capsid protein
HMOKDKBH_01120 4e-31 S Minor capsid protein
HMOKDKBH_01121 3e-51 S Minor capsid protein from bacteriophage
HMOKDKBH_01122 4.6e-83 N domain, Protein
HMOKDKBH_01123 8.7e-35
HMOKDKBH_01124 1.6e-85 S Bacteriophage Gp15 protein
HMOKDKBH_01125 0.0 xkdO D NLP P60 protein
HMOKDKBH_01126 2.5e-109 S phage tail
HMOKDKBH_01127 0.0 S Phage minor structural protein
HMOKDKBH_01129 2.9e-06 S Domain of unknown function (DUF2479)
HMOKDKBH_01130 1.4e-98 L Helix-turn-helix domain
HMOKDKBH_01131 5.4e-215 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HMOKDKBH_01132 6.5e-180 atl 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HMOKDKBH_01133 0.0 yjbQ P TrkA C-terminal domain protein
HMOKDKBH_01134 1.7e-106 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HMOKDKBH_01135 2.1e-161 S Oxidoreductase family, NAD-binding Rossmann fold
HMOKDKBH_01136 2.1e-130
HMOKDKBH_01137 2.1e-116
HMOKDKBH_01138 5e-133 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMOKDKBH_01139 1.4e-98 G Aldose 1-epimerase
HMOKDKBH_01140 2.7e-202 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HMOKDKBH_01141 1.6e-111 plsY 2.3.1.15 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HMOKDKBH_01142 0.0 XK27_08315 M Sulfatase
HMOKDKBH_01147 1.4e-13
HMOKDKBH_01151 6.1e-37 L HNH endonuclease
HMOKDKBH_01153 3e-25 L Phage terminase, small subunit
HMOKDKBH_01154 3.9e-180 S overlaps another CDS with the same product name
HMOKDKBH_01156 8.3e-101 S Phage portal protein
HMOKDKBH_01157 3.4e-52 S Clp protease
HMOKDKBH_01158 1.3e-88 S Phage capsid family
HMOKDKBH_01159 1.6e-14 S Phage gp6-like head-tail connector protein
HMOKDKBH_01160 1.1e-09 S Phage head-tail joining protein
HMOKDKBH_01161 1.3e-29 S Bacteriophage HK97-gp10, putative tail-component
HMOKDKBH_01162 1.8e-13 S Protein of unknown function (DUF806)
HMOKDKBH_01163 1.2e-28 S Phage tail tube protein
HMOKDKBH_01166 2.7e-141 xkdO D NLP P60 protein
HMOKDKBH_01167 1.2e-31 S phage tail
HMOKDKBH_01168 4.4e-252 S Phage minor structural protein
HMOKDKBH_01170 6e-12 S Domain of unknown function (DUF2479)
HMOKDKBH_01173 1.6e-110
HMOKDKBH_01174 1.1e-282 U Psort location Cytoplasmic, score
HMOKDKBH_01175 2.6e-109
HMOKDKBH_01183 1.9e-35 radC L DNA repair protein
HMOKDKBH_01184 2.3e-08 S Antirestriction protein (ArdA)
HMOKDKBH_01189 4.5e-30 dnaG L DNA primase activity
HMOKDKBH_01190 5.1e-88 3.4.22.70 M sortase family
HMOKDKBH_01196 1.9e-73
HMOKDKBH_01197 2.2e-12 ispH 1.17.7.4 J negative regulation of cytoplasmic translation
HMOKDKBH_01198 2.8e-218 3.2.1.97 GH101 M Psort location Cellwall, score
HMOKDKBH_01199 7e-22 S SLAP domain
HMOKDKBH_01200 3.8e-27
HMOKDKBH_01203 1e-88
HMOKDKBH_01206 1.5e-142 U TraM recognition site of TraD and TraG
HMOKDKBH_01212 5.9e-32
HMOKDKBH_01216 2.7e-49 M CHAP domain
HMOKDKBH_01218 1.2e-200 S regulation of response to stimulus
HMOKDKBH_01222 1.9e-57 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HMOKDKBH_01225 2.1e-06 L Initiator Replication protein
HMOKDKBH_01226 4.1e-48 dnaG 3.6.4.12 L DnaB-like helicase C terminal domain
HMOKDKBH_01227 3.5e-83 endA F DNA RNA non-specific endonuclease
HMOKDKBH_01235 8.1e-13
HMOKDKBH_01237 1.2e-225 L transposase, IS605 OrfB family
HMOKDKBH_01239 9.7e-15
HMOKDKBH_01240 7.3e-44
HMOKDKBH_01241 7.7e-257 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HMOKDKBH_01245 9.9e-15
HMOKDKBH_01246 1.6e-13
HMOKDKBH_01247 8.7e-58 L ribosomal rna small subunit methyltransferase
HMOKDKBH_01248 3.7e-56
HMOKDKBH_01249 2.6e-08 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HMOKDKBH_01251 1e-52 Q methyltransferase
HMOKDKBH_01252 2.5e-99 L Integrase
HMOKDKBH_01255 7.1e-267 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMOKDKBH_01256 5.8e-22
HMOKDKBH_01257 1.5e-180 S Domain of unknown function (DUF389)
HMOKDKBH_01258 8.7e-10 K FCD
HMOKDKBH_01259 4.7e-26 K FCD
HMOKDKBH_01260 1.6e-60 clcA P chloride
HMOKDKBH_01261 8.8e-41 clcA P chloride
HMOKDKBH_01262 5e-175 M Glycosyl transferases group 1
HMOKDKBH_01263 4e-81 M Glycosyltransferase, group 2 family protein
HMOKDKBH_01264 3.5e-68 MA20_43635 M Capsular polysaccharide synthesis protein
HMOKDKBH_01265 8.4e-265 S Fibronectin type III domain
HMOKDKBH_01266 4.5e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMOKDKBH_01267 3.4e-53
HMOKDKBH_01269 4.6e-257 pepC 3.4.22.40 E aminopeptidase
HMOKDKBH_01270 1.3e-122 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMOKDKBH_01271 1.7e-301 oppA E ABC transporter, substratebinding protein
HMOKDKBH_01272 1.6e-310 oppA E ABC transporter, substratebinding protein
HMOKDKBH_01273 3.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HMOKDKBH_01274 1.1e-146 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMOKDKBH_01275 8e-188 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMOKDKBH_01276 2.7e-199 oppD P Belongs to the ABC transporter superfamily
HMOKDKBH_01277 1.9e-175 oppF P Belongs to the ABC transporter superfamily
HMOKDKBH_01278 1.4e-256 pepC 3.4.22.40 E aminopeptidase
HMOKDKBH_01279 3.9e-72 hsp O Belongs to the small heat shock protein (HSP20) family
HMOKDKBH_01280 1.3e-28 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HMOKDKBH_01282 6.4e-70
HMOKDKBH_01283 3.4e-35
HMOKDKBH_01284 1.4e-09
HMOKDKBH_01285 7.4e-113 Z012_12235 S Baseplate J-like protein
HMOKDKBH_01286 7.4e-29
HMOKDKBH_01287 2.3e-36
HMOKDKBH_01288 1.3e-101
HMOKDKBH_01289 2.7e-46
HMOKDKBH_01290 9.4e-58 M LysM domain
HMOKDKBH_01291 1.5e-189 M Phage tail tape measure protein TP901
HMOKDKBH_01292 1.1e-11
HMOKDKBH_01293 1.3e-11
HMOKDKBH_01294 1.7e-133 Z012_02110 S Protein of unknown function (DUF3383)
HMOKDKBH_01295 1.6e-27
HMOKDKBH_01296 2e-10
HMOKDKBH_01297 9.1e-43
HMOKDKBH_01298 3.5e-27 S Protein of unknown function (DUF4054)
HMOKDKBH_01299 7.7e-37 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HMOKDKBH_01300 1e-22
HMOKDKBH_01301 3e-53 S Uncharacterized protein conserved in bacteria (DUF2213)
HMOKDKBH_01302 4.8e-20 S Lysin motif
HMOKDKBH_01303 2.1e-55 S Phage Mu protein F like protein
HMOKDKBH_01304 8.7e-92 S Protein of unknown function (DUF1073)
HMOKDKBH_01305 7.3e-187 S Terminase-like family
HMOKDKBH_01308 1.1e-20 S N-methyltransferase activity
HMOKDKBH_01314 5.5e-09
HMOKDKBH_01316 1e-10 S VRR_NUC
HMOKDKBH_01318 4e-69 S ORF6C domain
HMOKDKBH_01323 4.5e-49 Q DNA (cytosine-5-)-methyltransferase activity
HMOKDKBH_01328 1.5e-21 radC L DNA repair protein
HMOKDKBH_01329 8.1e-108 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
HMOKDKBH_01331 8.7e-20 K transcriptional
HMOKDKBH_01332 2.6e-23 K Conserved phage C-terminus (Phg_2220_C)
HMOKDKBH_01333 1.6e-44 S ERF superfamily
HMOKDKBH_01334 2e-54 S Protein of unknown function (DUF1351)
HMOKDKBH_01339 3.5e-09
HMOKDKBH_01341 4e-24 S Domain of unknown function (DUF771)
HMOKDKBH_01342 4.1e-15 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_01343 2.6e-18 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_01344 5.5e-07 S Pfam:DUF955
HMOKDKBH_01346 4.1e-153 L Belongs to the 'phage' integrase family
HMOKDKBH_01354 2.9e-174 L Bifunctional protein
HMOKDKBH_01355 6e-112
HMOKDKBH_01357 1.7e-110 E Belongs to the SOS response-associated peptidase family
HMOKDKBH_01358 3.7e-193 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMOKDKBH_01359 4e-89 comEB 3.5.4.12 F MafB19-like deaminase
HMOKDKBH_01360 2e-103 S TPM domain
HMOKDKBH_01361 1.2e-131 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMOKDKBH_01362 5e-311 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMOKDKBH_01363 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMOKDKBH_01364 1e-147 tatD L hydrolase, TatD family
HMOKDKBH_01365 1e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HMOKDKBH_01366 6.7e-151 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HMOKDKBH_01367 4.5e-39 veg S Biofilm formation stimulator VEG
HMOKDKBH_01368 1.5e-147 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HMOKDKBH_01369 2.6e-173 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMOKDKBH_01370 5.3e-80
HMOKDKBH_01371 7.8e-292 S SLAP domain
HMOKDKBH_01372 6e-177 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMOKDKBH_01373 4.1e-93 L Transposase and inactivated derivatives, IS30 family
HMOKDKBH_01374 7.5e-64 M Glycosyltransferase, group 2 family protein
HMOKDKBH_01375 2.4e-65 M Glycosyltransferase sugar-binding region containing DXD motif
HMOKDKBH_01376 7.6e-25 S SLAP domain
HMOKDKBH_01377 4.3e-24 S SLAP domain
HMOKDKBH_01378 2.5e-15
HMOKDKBH_01380 2.3e-69 S AAA domain
HMOKDKBH_01381 5e-30 S HNH endonuclease
HMOKDKBH_01387 8.2e-26
HMOKDKBH_01388 9.1e-123 K ORF6N domain
HMOKDKBH_01389 3.6e-16 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_01390 1.4e-16
HMOKDKBH_01393 2.8e-168 2.7.1.2 GK ROK family
HMOKDKBH_01394 2.1e-42
HMOKDKBH_01395 3.6e-268 ywfO S Metal dependent phosphohydrolases with conserved 'HD' motif.
HMOKDKBH_01396 6.9e-69 S Domain of unknown function (DUF1934)
HMOKDKBH_01397 1.5e-46 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HMOKDKBH_01398 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HMOKDKBH_01399 9.6e-247 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMOKDKBH_01400 1.8e-74 K acetyltransferase
HMOKDKBH_01401 2.2e-284 pipD E Dipeptidase
HMOKDKBH_01402 3.7e-156 msmR K AraC-like ligand binding domain
HMOKDKBH_01403 1.5e-223 pbuX F xanthine permease
HMOKDKBH_01404 9e-104 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HMOKDKBH_01405 2.4e-43 K Helix-turn-helix
HMOKDKBH_01406 7.8e-304 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HMOKDKBH_01408 4.9e-99 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HMOKDKBH_01409 3.6e-225 3.2.1.18 GH33 M Rib/alpha-like repeat
HMOKDKBH_01410 2.9e-247 mntH P H( )-stimulated, divalent metal cation uptake system
HMOKDKBH_01411 5.3e-45 yitW S Iron-sulfur cluster assembly protein
HMOKDKBH_01412 2e-266 sufB O assembly protein SufB
HMOKDKBH_01413 2.4e-59 nifU C SUF system FeS assembly protein, NifU family
HMOKDKBH_01414 5.3e-178 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HMOKDKBH_01415 3.5e-174 sufD O FeS assembly protein SufD
HMOKDKBH_01416 2.8e-140 sufC O FeS assembly ATPase SufC
HMOKDKBH_01417 5.1e-136 L Transposase
HMOKDKBH_01419 8.2e-85 scrR K Periplasmic binding protein domain
HMOKDKBH_01420 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
HMOKDKBH_01421 2.2e-54 oppA E ABC transporter substrate-binding protein
HMOKDKBH_01422 8.1e-149 oppA E ABC transporter substrate-binding protein
HMOKDKBH_01428 6.5e-47 xerD L Phage integrase, N-terminal SAM-like domain
HMOKDKBH_01429 2.9e-46 V Transport permease protein
HMOKDKBH_01430 3.4e-09
HMOKDKBH_01431 1.1e-68 sagB C Nitroreductase family
HMOKDKBH_01432 5.1e-56
HMOKDKBH_01433 1.8e-131 sagD S YcaO cyclodehydratase, ATP-ad Mg2+-binding
HMOKDKBH_01435 1.3e-128 L Transposase
HMOKDKBH_01437 5.2e-104
HMOKDKBH_01438 1.7e-145 3.2.1.18 GH33 M Rib/alpha-like repeat
HMOKDKBH_01440 1.7e-77 2.5.1.74 H UbiA prenyltransferase family
HMOKDKBH_01441 1e-95
HMOKDKBH_01442 9.1e-66 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01443 5.8e-28 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01445 4.5e-34 S phage tail
HMOKDKBH_01446 2.6e-139 S Phage minor structural protein
HMOKDKBH_01448 3.5e-16 S Helix-turn-helix domain
HMOKDKBH_01449 6.1e-60 V Abi-like protein
HMOKDKBH_01450 1.3e-141 yfeO P Voltage gated chloride channel
HMOKDKBH_01451 1.4e-184 5.3.3.2 C FMN-dependent dehydrogenase
HMOKDKBH_01452 1.4e-51
HMOKDKBH_01453 2.1e-42
HMOKDKBH_01454 6.4e-232 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMOKDKBH_01455 9.5e-297 ybeC E amino acid
HMOKDKBH_01456 2.6e-157 S Sucrose-6F-phosphate phosphohydrolase
HMOKDKBH_01457 0.0 dexB 3.2.1.10, 3.2.1.70 GH13 G Alpha amylase, catalytic domain protein
HMOKDKBH_01458 2.5e-39 rpmE2 J Ribosomal protein L31
HMOKDKBH_01459 2.6e-258 murF 6.3.2.10, 6.3.2.13 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HMOKDKBH_01460 4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HMOKDKBH_01461 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HMOKDKBH_01462 1e-215 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HMOKDKBH_01463 4.1e-33 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HMOKDKBH_01464 2.8e-48 S Peptidase propeptide and YPEB domain
HMOKDKBH_01472 1.6e-84 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMOKDKBH_01473 7e-20 L hmm pf00665
HMOKDKBH_01474 2.5e-52 S Membrane protein involved in the export of O-antigen and teichoic acid
HMOKDKBH_01475 3.3e-08 cat S Bacterial transferase hexapeptide (six repeats)
HMOKDKBH_01476 6.6e-34 CBM50 M NlpC P60 family protein
HMOKDKBH_01477 1.8e-06
HMOKDKBH_01481 3.6e-255 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMOKDKBH_01482 1.5e-117 U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMOKDKBH_01486 9.5e-220 L Belongs to the 'phage' integrase family
HMOKDKBH_01487 2.3e-26
HMOKDKBH_01488 3.9e-55
HMOKDKBH_01489 5.1e-145 S Replication initiation factor
HMOKDKBH_01490 1.4e-134 D Ftsk spoiiie family protein
HMOKDKBH_01491 2.6e-84
HMOKDKBH_01492 6.9e-64
HMOKDKBH_01493 1.5e-234 L Transposase DDE domain
HMOKDKBH_01494 3.4e-129 S (CBS) domain
HMOKDKBH_01495 1.5e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMOKDKBH_01496 5.1e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HMOKDKBH_01497 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMOKDKBH_01498 1.6e-33 yabO J S4 domain protein
HMOKDKBH_01499 6.8e-60 divIC D Septum formation initiator
HMOKDKBH_01500 1.8e-62 yabR J S1 RNA binding domain
HMOKDKBH_01501 2.6e-241 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HMOKDKBH_01502 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMOKDKBH_01503 9.7e-166 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMOKDKBH_01504 2e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMOKDKBH_01505 4.2e-297 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HMOKDKBH_01506 1.4e-83 K FR47-like protein
HMOKDKBH_01507 1.6e-08
HMOKDKBH_01508 1.6e-08
HMOKDKBH_01509 1.6e-08
HMOKDKBH_01511 3.5e-70 yebR 1.8.4.14 T GAF domain-containing protein
HMOKDKBH_01515 1e-11 S SLAP domain
HMOKDKBH_01516 1.8e-24 srtA 3.4.22.70 M sortase family
HMOKDKBH_01518 1.3e-41 M domain protein
HMOKDKBH_01519 6.8e-15 S SLAP domain
HMOKDKBH_01520 7.9e-31 M domain protein
HMOKDKBH_01524 4.8e-142 U TraM recognition site of TraD and TraG
HMOKDKBH_01525 3.9e-32 I mechanosensitive ion channel activity
HMOKDKBH_01527 8.4e-15
HMOKDKBH_01528 1.8e-159 trsE S COG0433 Predicted ATPase
HMOKDKBH_01529 9.4e-33 M Peptidase family M23
HMOKDKBH_01532 1.4e-31 O OsmC-like protein
HMOKDKBH_01534 1.5e-36 oppA E ABC transporter substrate-binding protein
HMOKDKBH_01535 3.2e-19 ps115 K sequence-specific DNA binding
HMOKDKBH_01536 1.3e-19 S Pfam:Peptidase_M78
HMOKDKBH_01537 1.2e-39 C 2Fe-2S iron-sulfur cluster binding domain
HMOKDKBH_01538 6.3e-62 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01539 3.3e-164 phnD P ABC transporter, phosphonate, periplasmic substrate-binding protein
HMOKDKBH_01540 5.2e-170 degV S DegV family
HMOKDKBH_01541 1.1e-135 V ABC transporter transmembrane region
HMOKDKBH_01542 1.8e-167 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HMOKDKBH_01544 1.4e-16
HMOKDKBH_01545 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HMOKDKBH_01546 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMOKDKBH_01547 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMOKDKBH_01548 3.6e-120 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HMOKDKBH_01549 7.8e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMOKDKBH_01550 2.7e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HMOKDKBH_01551 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMOKDKBH_01552 1.4e-140 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01553 1.1e-74 L Transposase
HMOKDKBH_01554 3.4e-140 L reverse transcriptase
HMOKDKBH_01555 4.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HMOKDKBH_01556 3.4e-112 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMOKDKBH_01557 2.1e-106 rplD J Forms part of the polypeptide exit tunnel
HMOKDKBH_01558 3.1e-47 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HMOKDKBH_01559 3.6e-154 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMOKDKBH_01560 1.1e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMOKDKBH_01561 4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMOKDKBH_01562 2.7e-120 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HMOKDKBH_01563 2.1e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMOKDKBH_01564 1.3e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HMOKDKBH_01565 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMOKDKBH_01566 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMOKDKBH_01567 3.4e-33 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMOKDKBH_01568 5.5e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMOKDKBH_01569 8.9e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMOKDKBH_01570 3.2e-68 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMOKDKBH_01571 3.3e-92 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMOKDKBH_01572 3.6e-55 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMOKDKBH_01573 4.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HMOKDKBH_01574 2.3e-24 rpmD J Ribosomal protein L30
HMOKDKBH_01575 1.3e-70 rplO J Binds to the 23S rRNA
HMOKDKBH_01576 1.4e-237 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HMOKDKBH_01577 3.5e-120 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HMOKDKBH_01578 8.4e-34 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HMOKDKBH_01579 7.8e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HMOKDKBH_01580 4.2e-56 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMOKDKBH_01581 3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMOKDKBH_01582 1.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HMOKDKBH_01583 1.4e-60 rplQ J Ribosomal protein L17
HMOKDKBH_01584 1.4e-153 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMOKDKBH_01585 3.5e-157 ecfA 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMOKDKBH_01586 8.5e-137 ecfT U Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HMOKDKBH_01587 4.8e-148 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HMOKDKBH_01588 5.9e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMOKDKBH_01589 5.1e-66 rpsI J Belongs to the universal ribosomal protein uS9 family
HMOKDKBH_01590 3.6e-183 L Phage integrase family
HMOKDKBH_01592 1.6e-77 ybhL S Belongs to the BI1 family
HMOKDKBH_01594 1.1e-23 S Hypothetical protein (DUF2513)
HMOKDKBH_01595 4.2e-96 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01596 6.3e-105 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
HMOKDKBH_01597 3.3e-118 3.1.3.18, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMOKDKBH_01598 6e-132 S membrane transporter protein
HMOKDKBH_01599 3.7e-125 gpmB G Belongs to the phosphoglycerate mutase family
HMOKDKBH_01600 7.3e-161 czcD P cation diffusion facilitator family transporter
HMOKDKBH_01601 1.4e-23
HMOKDKBH_01602 2.6e-126 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMOKDKBH_01603 5.4e-183 S AAA domain
HMOKDKBH_01604 7.3e-44
HMOKDKBH_01605 1e-267 pepC 3.4.22.40 E Peptidase C1-like family
HMOKDKBH_01606 4.1e-52
HMOKDKBH_01607 1.8e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HMOKDKBH_01608 2.7e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HMOKDKBH_01609 1.6e-290 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMOKDKBH_01610 7.5e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HMOKDKBH_01611 5.1e-75 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HMOKDKBH_01612 1.7e-139 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMOKDKBH_01613 1.2e-94 sigH K Belongs to the sigma-70 factor family
HMOKDKBH_01614 1.7e-34
HMOKDKBH_01615 8.4e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
HMOKDKBH_01616 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMOKDKBH_01617 3.6e-24 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HMOKDKBH_01618 1.2e-100 nusG K Participates in transcription elongation, termination and antitermination
HMOKDKBH_01619 1.2e-68 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMOKDKBH_01620 3.2e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HMOKDKBH_01621 2.8e-157 pstS P Phosphate
HMOKDKBH_01622 1.9e-162 pstC P probably responsible for the translocation of the substrate across the membrane
HMOKDKBH_01623 6.5e-154 pstA P Phosphate transport system permease protein PstA
HMOKDKBH_01624 5e-145 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMOKDKBH_01625 3.9e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HMOKDKBH_01626 2.2e-117 phoU P Plays a role in the regulation of phosphate uptake
HMOKDKBH_01627 2.8e-90 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01628 1.5e-11 GT2,GT4 M family 8
HMOKDKBH_01629 7e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMOKDKBH_01630 1.8e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HMOKDKBH_01631 8.7e-140 potC 2.1.1.172, 2.1.1.80, 3.1.1.61 J Ion channel
HMOKDKBH_01632 1.3e-116 rsmC 2.1.1.172 J Methyltransferase
HMOKDKBH_01633 9e-26
HMOKDKBH_01634 2.2e-90 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HMOKDKBH_01635 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HMOKDKBH_01636 5.7e-106 2.4.1.58 GT8 M family 8
HMOKDKBH_01637 1.2e-35 M lipopolysaccharide 3-alpha-galactosyltransferase activity
HMOKDKBH_01638 8.2e-41 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HMOKDKBH_01639 1.6e-108 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMOKDKBH_01640 1.1e-34 S Protein of unknown function (DUF2508)
HMOKDKBH_01641 1.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMOKDKBH_01642 8.9e-53 yaaQ S Cyclic-di-AMP receptor
HMOKDKBH_01643 1.5e-155 holB 2.7.7.7 L DNA polymerase III
HMOKDKBH_01644 1.8e-59 yabA L Involved in initiation control of chromosome replication
HMOKDKBH_01645 5.1e-156 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMOKDKBH_01646 1.4e-130 fat 3.1.2.21 I Acyl-ACP thioesterase
HMOKDKBH_01647 2.2e-85 S ECF transporter, substrate-specific component
HMOKDKBH_01648 2.4e-133 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HMOKDKBH_01649 7.4e-97 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HMOKDKBH_01650 4.5e-194 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HMOKDKBH_01651 1.9e-245 L Transposase IS66 family
HMOKDKBH_01652 8.7e-34 S Transposase C of IS166 homeodomain
HMOKDKBH_01653 9.3e-64 L PFAM IS66 Orf2 family protein
HMOKDKBH_01654 7.7e-22
HMOKDKBH_01655 7e-43 yfdE 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMOKDKBH_01656 6.6e-182 frc 2.8.3.16, 2.8.3.19 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
HMOKDKBH_01657 3.4e-284 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
HMOKDKBH_01658 0.0 uup S ABC transporter, ATP-binding protein
HMOKDKBH_01659 5.8e-112 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HMOKDKBH_01660 1.3e-29 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HMOKDKBH_01661 2.8e-53 L Transposase
HMOKDKBH_01662 1.7e-87 L Transposase
HMOKDKBH_01663 2e-192 L COG2963 Transposase and inactivated derivatives
HMOKDKBH_01665 7.8e-43 L PFAM transposase IS116 IS110 IS902
HMOKDKBH_01666 1.1e-183 scrR K helix_turn _helix lactose operon repressor
HMOKDKBH_01667 3.7e-295 scrB 3.2.1.26 GH32 G invertase
HMOKDKBH_01668 0.0 scrA 2.7.1.208, 2.7.1.211, 5.3.1.1 G phosphotransferase system
HMOKDKBH_01669 2.3e-181 M CHAP domain
HMOKDKBH_01670 3.5e-75
HMOKDKBH_01671 1.4e-41 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMOKDKBH_01672 5.9e-294 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HMOKDKBH_01673 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMOKDKBH_01674 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMOKDKBH_01675 1.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HMOKDKBH_01676 1.5e-186 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HMOKDKBH_01677 9.6e-41 yajC U Preprotein translocase
HMOKDKBH_01681 9.6e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMOKDKBH_01682 6.2e-210 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HMOKDKBH_01683 1.4e-181 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HMOKDKBH_01684 2e-226 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HMOKDKBH_01685 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMOKDKBH_01686 2e-42 yrzL S Belongs to the UPF0297 family
HMOKDKBH_01687 6.1e-73 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMOKDKBH_01688 1.1e-50 yrzB S Belongs to the UPF0473 family
HMOKDKBH_01689 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMOKDKBH_01690 3.5e-54 trxA O Belongs to the thioredoxin family
HMOKDKBH_01691 9.7e-59 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HMOKDKBH_01692 1.1e-71 yslB S Protein of unknown function (DUF2507)
HMOKDKBH_01693 6.6e-145 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HMOKDKBH_01694 1.1e-110 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMOKDKBH_01695 7.7e-30 ropB K Helix-turn-helix domain
HMOKDKBH_01696 5.4e-113
HMOKDKBH_01697 1.7e-139
HMOKDKBH_01698 6.9e-100 V ATPases associated with a variety of cellular activities
HMOKDKBH_01699 3.7e-146 ykuT M mechanosensitive ion channel
HMOKDKBH_01700 9.5e-10 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HMOKDKBH_01701 1.3e-36
HMOKDKBH_01702 7e-214 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HMOKDKBH_01703 3.2e-181 ccpA K catabolite control protein A
HMOKDKBH_01704 2.3e-267 ugpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMOKDKBH_01705 4.3e-55
HMOKDKBH_01706 5.8e-274 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HMOKDKBH_01707 2.1e-92 yutD S Protein of unknown function (DUF1027)
HMOKDKBH_01708 3.4e-143 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HMOKDKBH_01709 3.7e-100 S Protein of unknown function (DUF1461)
HMOKDKBH_01710 1.4e-39 L Transposase and inactivated derivatives, IS30 family
HMOKDKBH_01711 1.2e-112 dedA S SNARE-like domain protein
HMOKDKBH_01712 7.5e-183 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
HMOKDKBH_01713 5.1e-106 fabK 1.3.1.9 S Nitronate monooxygenase
HMOKDKBH_01731 1.7e-74 sip L Belongs to the 'phage' integrase family
HMOKDKBH_01734 1.4e-16 K Transcriptional
HMOKDKBH_01736 3.3e-112 K BRO family, N-terminal domain
HMOKDKBH_01738 9.8e-09
HMOKDKBH_01740 1.3e-85 S Protein of unknown function (DUF1351)
HMOKDKBH_01741 6.9e-75 S ERF superfamily
HMOKDKBH_01742 2.3e-67 L DnaD domain protein
HMOKDKBH_01749 1.7e-07
HMOKDKBH_01750 7.2e-23 N PFAM Uncharacterised protein family UPF0150
HMOKDKBH_01751 8.5e-279 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
HMOKDKBH_01752 6.8e-226 I Protein of unknown function (DUF2974)
HMOKDKBH_01753 1.9e-116 yhiD S MgtC family
HMOKDKBH_01757 1.8e-38 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMOKDKBH_01758 2.3e-103 M hydrolase, family 25
HMOKDKBH_01774 7.9e-224 mgs 2.4.1.337 GT4 M Glycosyl transferase 4-like domain
HMOKDKBH_01775 7.6e-202 cpoA GT4 M Glycosyltransferase, group 1 family protein
HMOKDKBH_01776 1.4e-176 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HMOKDKBH_01777 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMOKDKBH_01778 1.7e-29 secG U Preprotein translocase
HMOKDKBH_01779 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HMOKDKBH_01780 5.1e-78 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HMOKDKBH_01783 1.7e-16
HMOKDKBH_01785 7e-16
HMOKDKBH_01786 8e-27
HMOKDKBH_01787 1.8e-79
HMOKDKBH_01789 2.5e-186 manL 2.7.1.191 G PTS system sorbose subfamily IIB component
HMOKDKBH_01790 1.7e-129 manY G PTS system
HMOKDKBH_01791 1e-173 manN G system, mannose fructose sorbose family IID component
HMOKDKBH_01792 1.1e-62 manO S Domain of unknown function (DUF956)
HMOKDKBH_01793 3.3e-158 K Transcriptional regulator
HMOKDKBH_01794 1.3e-85 maa S transferase hexapeptide repeat
HMOKDKBH_01795 4.4e-242 cycA E Amino acid permease
HMOKDKBH_01796 7.6e-49 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMOKDKBH_01797 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HMOKDKBH_01798 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HMOKDKBH_01799 0.0 mtlR K Mga helix-turn-helix domain
HMOKDKBH_01800 5.2e-265 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_01801 1.6e-32 mtlA 2.7.1.197 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_01802 2.1e-79 mtlF 2.7.1.197 G catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_01803 1e-218 mtlD 1.1.1.17 C mannitol-1-phosphate 5-dehydrogenase activity
HMOKDKBH_01804 3.2e-28 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMOKDKBH_01805 2.3e-78 4.1.1.44 S Carboxymuconolactone decarboxylase family
HMOKDKBH_01806 2.1e-32
HMOKDKBH_01807 3.7e-59 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HMOKDKBH_01808 2.3e-156 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_01809 3.9e-298 V ABC transporter transmembrane region
HMOKDKBH_01810 0.0 pckA 4.1.1.49 H Phosphoenolpyruvate carboxykinase
HMOKDKBH_01811 1.7e-193 S TerB-C domain
HMOKDKBH_01812 9.3e-116 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
HMOKDKBH_01813 1.4e-107 M Transport protein ComB
HMOKDKBH_01814 2e-73 L Transposase
HMOKDKBH_01815 2.6e-138 S TerB-C domain
HMOKDKBH_01816 1.4e-245 P P-loop Domain of unknown function (DUF2791)
HMOKDKBH_01817 0.0 lhr L DEAD DEAH box helicase
HMOKDKBH_01818 1.4e-60
HMOKDKBH_01819 4.3e-228 amtB P ammonium transporter
HMOKDKBH_01820 7.8e-45 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMOKDKBH_01821 1e-63 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
HMOKDKBH_01823 6.6e-61 psiE S Phosphate-starvation-inducible E
HMOKDKBH_01824 6.5e-113 yncA 2.3.1.79 S Maltose acetyltransferase
HMOKDKBH_01825 2.9e-69 S Iron-sulphur cluster biosynthesis
HMOKDKBH_01827 2.3e-30
HMOKDKBH_01828 2.6e-171 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HMOKDKBH_01829 6.2e-12
HMOKDKBH_01830 1.5e-16 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_01831 4.1e-78 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_01832 2.8e-86 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_01833 5.8e-78 M LysM domain protein
HMOKDKBH_01834 4.7e-159 D nuclear chromosome segregation
HMOKDKBH_01835 1.2e-105 G Phosphoglycerate mutase family
HMOKDKBH_01836 2.6e-89 G Histidine phosphatase superfamily (branch 1)
HMOKDKBH_01837 6.6e-119 VY92_08690 5.3.1.32 G Antibiotic biosynthesis monooxygenase
HMOKDKBH_01838 1.2e-115 glpQ1 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HMOKDKBH_01840 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
HMOKDKBH_01842 6.5e-210 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
HMOKDKBH_01843 2e-109 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HMOKDKBH_01844 1.8e-65 XK27_10475 S Oxidoreductase family, NAD-binding Rossmann fold
HMOKDKBH_01845 8.1e-120 rpiA 5.3.1.6 G Ribose 5-phosphate isomerase A (phosphoriboisomerase A)
HMOKDKBH_01846 4.4e-144 K SIS domain
HMOKDKBH_01847 4.8e-44 slpX S SLAP domain
HMOKDKBH_01848 5.3e-167 slpX S SLAP domain
HMOKDKBH_01849 1.3e-22 3.6.4.12 S transposase or invertase
HMOKDKBH_01850 6.6e-11
HMOKDKBH_01851 3.2e-240 npr 1.11.1.1 C NADH oxidase
HMOKDKBH_01854 4.4e-239 oppA2 E ABC transporter, substratebinding protein
HMOKDKBH_01855 3.4e-45 oppA2 E ABC transporter, substratebinding protein
HMOKDKBH_01856 3.3e-179
HMOKDKBH_01857 1.3e-125 gntR1 K UTRA
HMOKDKBH_01858 5.1e-71 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HMOKDKBH_01859 2.1e-134 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HMOKDKBH_01860 1.7e-204 csaB M Glycosyl transferases group 1
HMOKDKBH_01861 2.4e-286 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HMOKDKBH_01862 1.2e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HMOKDKBH_01863 1.4e-204 tnpB L Putative transposase DNA-binding domain
HMOKDKBH_01864 3.8e-250 pacL 3.6.3.8 P P-type ATPase
HMOKDKBH_01865 1.8e-226 pacL 3.6.3.8 P P-type ATPase
HMOKDKBH_01866 7e-225 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HMOKDKBH_01867 6e-258 epsU S Polysaccharide biosynthesis protein
HMOKDKBH_01868 7.7e-134 M Glycosyltransferase sugar-binding region containing DXD motif
HMOKDKBH_01869 4.1e-83 ydcK S Belongs to the SprT family
HMOKDKBH_01871 5.2e-84 acmC 3.2.1.17, 3.2.1.96 NU mannosyl-glycoprotein
HMOKDKBH_01872 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HMOKDKBH_01873 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMOKDKBH_01874 5.8e-203 camS S sex pheromone
HMOKDKBH_01875 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMOKDKBH_01876 2.9e-268 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HMOKDKBH_01877 2.7e-274 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMOKDKBH_01878 2.7e-171 yegS 2.7.1.107 G Lipid kinase
HMOKDKBH_01879 4.3e-108 ybhL S Belongs to the BI1 family
HMOKDKBH_01880 2.6e-57
HMOKDKBH_01881 1.4e-147 I transferase activity, transferring acyl groups other than amino-acyl groups
HMOKDKBH_01882 2.8e-244 nhaC C Na H antiporter NhaC
HMOKDKBH_01883 6.3e-201 pbpX V Beta-lactamase
HMOKDKBH_01884 4.9e-254 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMOKDKBH_01885 4.3e-94 MA20_25245 K Acetyltransferase (GNAT) domain
HMOKDKBH_01890 1.9e-259 emrY EGP Major facilitator Superfamily
HMOKDKBH_01891 2e-91 yxdD K Bacterial regulatory proteins, tetR family
HMOKDKBH_01892 0.0 4.2.1.53 S Myosin-crossreactive antigen
HMOKDKBH_01893 5.5e-148 S cog cog1373
HMOKDKBH_01894 8.2e-128 L Transposase
HMOKDKBH_01895 5.8e-85 2.3.1.128 K Acetyltransferase (GNAT) domain
HMOKDKBH_01896 2e-157 S reductase
HMOKDKBH_01897 9.3e-35
HMOKDKBH_01899 5e-78 K Putative DNA-binding domain
HMOKDKBH_01900 2.2e-22
HMOKDKBH_01901 3.3e-140 repB EP Plasmid replication protein
HMOKDKBH_01902 2.1e-79 S helix_turn_helix, Deoxyribose operon repressor
HMOKDKBH_01903 8.7e-86 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HMOKDKBH_01904 3.2e-139 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMOKDKBH_01906 1.9e-22 K Putative DNA-binding domain
HMOKDKBH_01907 7.6e-239 pyrP F Permease
HMOKDKBH_01908 8.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HMOKDKBH_01909 9.2e-262 emrY EGP Major facilitator Superfamily
HMOKDKBH_01910 5.1e-155 mdtG EGP Major facilitator Superfamily
HMOKDKBH_01911 4.7e-182 pepA E M42 glutamyl aminopeptidase
HMOKDKBH_01912 2.2e-311 ybiT S ABC transporter, ATP-binding protein
HMOKDKBH_01913 5.9e-174 S Aldo keto reductase
HMOKDKBH_01914 2.7e-138
HMOKDKBH_01915 2.8e-202 steT E amino acid
HMOKDKBH_01916 2.4e-26 steT E amino acid
HMOKDKBH_01917 9.8e-239 steT E amino acid
HMOKDKBH_01918 1.9e-129 yfeJ 6.3.5.2 F glutamine amidotransferase
HMOKDKBH_01919 1.9e-147 glnH ET ABC transporter
HMOKDKBH_01920 1.4e-80 K Transcriptional regulator, MarR family
HMOKDKBH_01921 6.9e-309 XK27_09600 V ABC transporter, ATP-binding protein
HMOKDKBH_01922 0.0 V ABC transporter transmembrane region
HMOKDKBH_01923 1.6e-100 S ABC-type cobalt transport system, permease component
HMOKDKBH_01924 1e-246 G MFS/sugar transport protein
HMOKDKBH_01925 9.8e-39 udk 2.7.1.48 F Zeta toxin
HMOKDKBH_01926 3.8e-46 udk 2.7.1.48 F Zeta toxin
HMOKDKBH_01927 4.8e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HMOKDKBH_01928 1.2e-146 glnH ET ABC transporter substrate-binding protein
HMOKDKBH_01929 3.7e-90 gluC P ABC transporter permease
HMOKDKBH_01930 4.7e-109 glnP P ABC transporter permease
HMOKDKBH_01931 1.1e-164 S Protein of unknown function (DUF2974)
HMOKDKBH_01932 5.6e-86
HMOKDKBH_01933 2.5e-75 K Helix-turn-helix domain
HMOKDKBH_01934 1.5e-25 S CAAX protease self-immunity
HMOKDKBH_01935 1.4e-22 S CAAX protease self-immunity
HMOKDKBH_01936 7.6e-26 WQ51_00220 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_01938 1.6e-96 ybaT E Amino acid permease
HMOKDKBH_01939 1.7e-07 S LPXTG cell wall anchor motif
HMOKDKBH_01940 4.4e-146 S Putative ABC-transporter type IV
HMOKDKBH_01942 9.6e-28 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMOKDKBH_01943 0.0 ftsZ M Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMOKDKBH_01944 2e-116 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMOKDKBH_01945 1.2e-232 oppA E ABC transporter substrate-binding protein
HMOKDKBH_01946 2.1e-95 oppA E ABC transporter substrate-binding protein
HMOKDKBH_01947 1.3e-128 L Transposase
HMOKDKBH_01948 8e-12 relB L RelB antitoxin
HMOKDKBH_01949 3.2e-15 relB L RelB antitoxin
HMOKDKBH_01950 1.6e-35 S Bacterial toxin of type II toxin-antitoxin system, YafQ
HMOKDKBH_01951 3.3e-86 bcgIB 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
HMOKDKBH_01952 3.3e-241 V N-6 DNA Methylase
HMOKDKBH_01953 8.9e-103 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01954 8.3e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMOKDKBH_01955 3.5e-57 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMOKDKBH_01956 6.5e-18 2.7.1.200 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_01957 9.7e-205 gatC G PTS system sugar-specific permease component
HMOKDKBH_01958 1.2e-24 2.7.1.200, 2.7.1.202 G phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2
HMOKDKBH_01960 7.9e-16 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01961 9.4e-51 L An automated process has identified a potential problem with this gene model
HMOKDKBH_01963 1e-66 doc S Fic/DOC family
HMOKDKBH_01964 4.1e-34
HMOKDKBH_01966 1.1e-23 S CAAX protease self-immunity
HMOKDKBH_01968 3.7e-133 topA2 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HMOKDKBH_01970 9.6e-18 S PemK-like, MazF-like toxin of type II toxin-antitoxin system
HMOKDKBH_01971 3.4e-24 relB L Addiction module antitoxin, RelB DinJ family
HMOKDKBH_01972 2.5e-47 L Psort location Cytoplasmic, score
HMOKDKBH_01973 4.6e-111 S Fic/DOC family
HMOKDKBH_01974 1.7e-39 L Protein of unknown function (DUF3991)
HMOKDKBH_01975 3.4e-52 S COG0790 FOG TPR repeat, SEL1 subfamily
HMOKDKBH_01979 1.9e-19 L Replication initiation factor
HMOKDKBH_01980 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMOKDKBH_01981 9.3e-74 nrdI F NrdI Flavodoxin like
HMOKDKBH_01982 3.6e-193 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMOKDKBH_01983 1.1e-109 tnpR1 L Resolvase, N terminal domain
HMOKDKBH_01984 4.7e-70 L IS1381, transposase OrfA
HMOKDKBH_01985 1.1e-76 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMOKDKBH_01986 1.3e-28
HMOKDKBH_01987 1.7e-142 soj D AAA domain
HMOKDKBH_01988 1.9e-166 repA S Replication initiator protein A
HMOKDKBH_01989 8.5e-128 S Fic/DOC family
HMOKDKBH_01990 5.4e-60 L Resolvase, N-terminal
HMOKDKBH_01991 1.6e-166 L Putative transposase DNA-binding domain
HMOKDKBH_01992 1e-190 L Transposase and inactivated derivatives, IS30 family
HMOKDKBH_01998 8.1e-175 ulaG S Beta-lactamase superfamily domain
HMOKDKBH_01999 1.5e-61 cmtB 2.7.1.194, 2.7.1.197, 2.7.1.200, 2.7.1.202 G Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
HMOKDKBH_02000 1.3e-231 ulaA S PTS system sugar-specific permease component
HMOKDKBH_02001 4.1e-31 sgaB 2.7.1.194 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_02002 2.8e-90 ulaD 4.1.1.85, 4.1.2.43 G Orotidine 5'-phosphate decarboxylase / HUMPS family
HMOKDKBH_02003 7.2e-129 ulaE 5.1.3.22 G Xylose isomerase-like TIM barrel
HMOKDKBH_02004 4.9e-123 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HMOKDKBH_02005 5.2e-68 L haloacid dehalogenase-like hydrolase
HMOKDKBH_02006 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMOKDKBH_02007 1.4e-16 L Transposase
HMOKDKBH_02008 1.9e-12 L Transposase
HMOKDKBH_02009 5.9e-13 K Acetyltransferase (GNAT) domain
HMOKDKBH_02010 6.3e-212 S Uncharacterized protein conserved in bacteria (DUF2325)
HMOKDKBH_02011 1.3e-235 G Bacterial extracellular solute-binding protein
HMOKDKBH_02012 7.7e-162 2.7.7.12 C Domain of unknown function (DUF4931)
HMOKDKBH_02013 3.5e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMOKDKBH_02014 1e-125 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMOKDKBH_02015 0.0 kup P Transport of potassium into the cell
HMOKDKBH_02016 9.1e-175 rihB 3.2.2.1 F Nucleoside
HMOKDKBH_02017 2.8e-134 ydhQ K UbiC transcription regulator-associated domain protein
HMOKDKBH_02018 1.2e-154 S hydrolase
HMOKDKBH_02019 2.5e-59 S Enterocin A Immunity
HMOKDKBH_02020 3.1e-136 glcR K DeoR C terminal sensor domain
HMOKDKBH_02021 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
HMOKDKBH_02022 2e-160 rssA S Phospholipase, patatin family
HMOKDKBH_02023 5.4e-147 S hydrolase
HMOKDKBH_02024 0.0 glvC 2.7.1.199, 2.7.1.208, 2.7.1.211 G phosphotransferase system, EIIB
HMOKDKBH_02025 4.1e-147 glvR K Helix-turn-helix domain, rpiR family
HMOKDKBH_02026 1.6e-80
HMOKDKBH_02027 2.9e-87 pts23A G phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1
HMOKDKBH_02028 2.1e-39
HMOKDKBH_02029 3.9e-119 C nitroreductase
HMOKDKBH_02030 1.7e-249 yhdP S Transporter associated domain
HMOKDKBH_02031 3.4e-103 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HMOKDKBH_02032 0.0 1.3.5.4 C FAD binding domain
HMOKDKBH_02033 1.1e-87 L PFAM transposase, IS4 family protein
HMOKDKBH_02034 1.2e-49 L PFAM transposase, IS4 family protein
HMOKDKBH_02035 1.7e-213 1.3.5.4 C FAD binding domain
HMOKDKBH_02036 3.4e-126 1.3.5.4 C FAD binding domain
HMOKDKBH_02037 9.7e-231 potE E amino acid
HMOKDKBH_02038 4.8e-27 L Transposase
HMOKDKBH_02039 2.6e-61 M Glycosyl hydrolases family 25
HMOKDKBH_02040 1.3e-61 M Glycosyl hydrolases family 25
HMOKDKBH_02041 1.4e-210 yfmL 3.6.4.13 L DEAD DEAH box helicase
HMOKDKBH_02042 4.7e-249 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_02044 2e-216 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HMOKDKBH_02045 7e-87 gtcA S Teichoic acid glycosylation protein
HMOKDKBH_02046 4.1e-80 fld C Flavodoxin
HMOKDKBH_02047 1.4e-163 map 3.4.11.18 E Methionine Aminopeptidase
HMOKDKBH_02048 3.6e-163 yihY S Belongs to the UPF0761 family
HMOKDKBH_02049 2.1e-168 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HMOKDKBH_02050 5.6e-214 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HMOKDKBH_02051 3.6e-215 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HMOKDKBH_02052 9.4e-46
HMOKDKBH_02053 1.8e-38 D Alpha beta
HMOKDKBH_02054 1.4e-118 D Alpha beta
HMOKDKBH_02055 3e-262 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMOKDKBH_02056 1.5e-144 recX 2.4.1.337 GT4 S Regulatory protein RecX
HMOKDKBH_02057 1.6e-85
HMOKDKBH_02058 2.7e-74
HMOKDKBH_02059 1.4e-140 hlyX S Transporter associated domain
HMOKDKBH_02060 9.4e-305 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMOKDKBH_02061 2.3e-44 XK27_09445 S Domain of unknown function (DUF1827)
HMOKDKBH_02062 0.0 clpE O Belongs to the ClpA ClpB family
HMOKDKBH_02063 1e-162 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HMOKDKBH_02064 4.3e-52 K helix_turn_helix gluconate operon transcriptional repressor
HMOKDKBH_02065 4.1e-156 crtI 1.3.99.23, 5.2.1.13 Q HI0933-like protein
HMOKDKBH_02066 2.6e-65 C 2Fe-2S iron-sulfur cluster binding domain
HMOKDKBH_02067 3.3e-127 L PFAM transposase IS116 IS110 IS902
HMOKDKBH_02068 5.3e-26
HMOKDKBH_02069 8.5e-41 ptsH G phosphocarrier protein HPR
HMOKDKBH_02070 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HMOKDKBH_02071 3.9e-66 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMOKDKBH_02072 3.2e-138 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HMOKDKBH_02073 1.4e-158 coiA 3.6.4.12 S Competence protein
HMOKDKBH_02074 4.6e-114 yjbH Q Thioredoxin
HMOKDKBH_02075 6.8e-110 yjbK S CYTH
HMOKDKBH_02076 1.2e-114 yjbM 2.7.6.5 S RelA SpoT domain protein
HMOKDKBH_02077 3.8e-153 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMOKDKBH_02078 6.4e-173 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMOKDKBH_02079 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
HMOKDKBH_02080 4.2e-92 S SNARE associated Golgi protein
HMOKDKBH_02081 1.8e-200 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HMOKDKBH_02082 2.2e-66 srlB 2.7.1.198 G PTS system glucitol/sorbitol-specific IIA component
HMOKDKBH_02083 2.6e-214 yubA S AI-2E family transporter
HMOKDKBH_02084 4.2e-106 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HMOKDKBH_02085 1.7e-69 WQ51_03320 S Protein of unknown function (DUF1149)
HMOKDKBH_02086 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HMOKDKBH_02087 9e-223 2.7.1.26, 2.7.7.2 S Peptidase M16 inactive domain protein
HMOKDKBH_02088 1.9e-236 S Peptidase M16
HMOKDKBH_02089 2.3e-133 IQ Enoyl-(Acyl carrier protein) reductase
HMOKDKBH_02090 1.5e-96 ymfM S Helix-turn-helix domain
HMOKDKBH_02091 1.1e-95 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HMOKDKBH_02092 4.2e-195 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HMOKDKBH_02093 7.4e-220 rny S Endoribonuclease that initiates mRNA decay
HMOKDKBH_02094 1.3e-210 tagO 2.7.8.33, 2.7.8.35 M transferase
HMOKDKBH_02095 5.1e-119 yvyE 3.4.13.9 S YigZ family
HMOKDKBH_02096 4.7e-246 comFA L Helicase C-terminal domain protein
HMOKDKBH_02097 9.4e-132 comFC S Competence protein
HMOKDKBH_02098 1.6e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HMOKDKBH_02099 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HMOKDKBH_02100 4.6e-188 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HMOKDKBH_02101 5.1e-17
HMOKDKBH_02102 5.8e-180 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HMOKDKBH_02103 9.2e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMOKDKBH_02104 1.1e-186 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HMOKDKBH_02105 3.9e-181 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HMOKDKBH_02106 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HMOKDKBH_02107 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HMOKDKBH_02108 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HMOKDKBH_02109 4.1e-90 S Short repeat of unknown function (DUF308)
HMOKDKBH_02110 6.2e-165 rapZ S Displays ATPase and GTPase activities
HMOKDKBH_02111 4e-195 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HMOKDKBH_02112 2.1e-171 whiA K May be required for sporulation
HMOKDKBH_02113 2.3e-99 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HMOKDKBH_02114 0.0 S SH3-like domain
HMOKDKBH_02115 4.9e-111 ybbL S ABC transporter, ATP-binding protein
HMOKDKBH_02116 2.5e-130 ybbM S Uncharacterised protein family (UPF0014)
HMOKDKBH_02117 3.2e-176 K AI-2E family transporter
HMOKDKBH_02118 2.6e-103 3.1.1.5 E GDSL-like Lipase/Acylhydrolase
HMOKDKBH_02119 4.1e-18
HMOKDKBH_02120 4.1e-245 G Major Facilitator
HMOKDKBH_02121 1.3e-79 E Zn peptidase
HMOKDKBH_02122 1.2e-41 ps115 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02123 5.6e-45
HMOKDKBH_02124 4.5e-66 S Bacteriocin helveticin-J
HMOKDKBH_02125 1.7e-66 S SLAP domain
HMOKDKBH_02126 5.8e-45
HMOKDKBH_02127 2.4e-136 XK27_08845 S ABC transporter, ATP-binding protein
HMOKDKBH_02128 5.6e-121 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HMOKDKBH_02129 1.7e-174 ABC-SBP S ABC transporter
HMOKDKBH_02130 5.6e-132 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMOKDKBH_02131 1.6e-48 P CorA-like Mg2+ transporter protein
HMOKDKBH_02132 5.2e-75 P CorA-like Mg2+ transporter protein
HMOKDKBH_02133 3.5e-160 yvgN C Aldo keto reductase
HMOKDKBH_02134 0.0 tetP J elongation factor G
HMOKDKBH_02135 4e-150 3.1.3.102, 3.1.3.104 S haloacid dehalogenase-like hydrolase
HMOKDKBH_02136 1.2e-134 EGP Major facilitator Superfamily
HMOKDKBH_02138 3.1e-48 S Domain of unknown function (DUF4811)
HMOKDKBH_02139 1.8e-262 lmrB EGP Major facilitator Superfamily
HMOKDKBH_02140 4.2e-77 K MerR HTH family regulatory protein
HMOKDKBH_02141 3.1e-139 S Cysteine-rich secretory protein family
HMOKDKBH_02142 4.6e-274 ycaM E amino acid
HMOKDKBH_02143 2.8e-290
HMOKDKBH_02145 2.6e-189 cggR K Putative sugar-binding domain
HMOKDKBH_02146 6.5e-190 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HMOKDKBH_02147 1e-226 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HMOKDKBH_02148 1.7e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HMOKDKBH_02149 6e-199 L COG2826 Transposase and inactivated derivatives, IS30 family
HMOKDKBH_02150 1.2e-94
HMOKDKBH_02151 8.1e-85 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMOKDKBH_02152 1.7e-51 ycsE S Sucrose-6F-phosphate phosphohydrolase
HMOKDKBH_02153 9.7e-137 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMOKDKBH_02154 4.1e-181 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HMOKDKBH_02155 7e-86 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HMOKDKBH_02156 4e-98 dnaQ 2.7.7.7 L DNA polymerase III
HMOKDKBH_02157 5.9e-163 murB 1.3.1.98 M Cell wall formation
HMOKDKBH_02158 1.8e-206 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HMOKDKBH_02159 1.3e-129 potB P ABC transporter permease
HMOKDKBH_02160 4.8e-127 potC P ABC transporter permease
HMOKDKBH_02161 7.3e-208 potD P ABC transporter
HMOKDKBH_02162 6.4e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HMOKDKBH_02163 2e-172 ybbR S YbbR-like protein
HMOKDKBH_02164 3.1e-256 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMOKDKBH_02165 1.4e-147 S hydrolase
HMOKDKBH_02166 1.8e-75 K Penicillinase repressor
HMOKDKBH_02167 1.6e-118
HMOKDKBH_02168 7.4e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMOKDKBH_02169 3.8e-207 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HMOKDKBH_02170 8.3e-143 licT K CAT RNA binding domain
HMOKDKBH_02171 0.0 bglP 2.7.1.208, 2.7.1.211 G phosphotransferase system
HMOKDKBH_02172 6.7e-297 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMOKDKBH_02173 1e-149 D Alpha beta
HMOKDKBH_02174 1.9e-47 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HMOKDKBH_02175 2.4e-34 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
HMOKDKBH_02176 3.7e-26 queD 4.1.2.50, 4.2.3.12 H 6-pyruvoyl tetrahydropterin synthase
HMOKDKBH_02177 1.3e-110 ica2 GT2 M Glycosyl transferase family group 2
HMOKDKBH_02178 8.2e-36
HMOKDKBH_02179 2.2e-90 2.7.7.65 T GGDEF domain
HMOKDKBH_02180 8.8e-82 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMOKDKBH_02182 2e-310 E Amino acid permease
HMOKDKBH_02183 5.8e-100 L Helix-turn-helix domain
HMOKDKBH_02184 1.3e-160 L hmm pf00665
HMOKDKBH_02186 3.7e-27 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMOKDKBH_02187 3.5e-101 ylbE GM NAD(P)H-binding
HMOKDKBH_02188 7.6e-94 S VanZ like family
HMOKDKBH_02189 8.9e-133 yebC K Transcriptional regulatory protein
HMOKDKBH_02190 1.7e-179 comGA NU Type II IV secretion system protein
HMOKDKBH_02191 1.7e-171 comGB NU type II secretion system
HMOKDKBH_02192 3.1e-43 comGC U competence protein ComGC
HMOKDKBH_02193 1.8e-69
HMOKDKBH_02194 2.3e-41
HMOKDKBH_02195 3.8e-77 comGF U Putative Competence protein ComGF
HMOKDKBH_02196 1.6e-21
HMOKDKBH_02197 1.9e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HMOKDKBH_02198 6.3e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMOKDKBH_02201 1.2e-149 L Belongs to the 'phage' integrase family
HMOKDKBH_02202 5e-08 S Pfam:DUF955
HMOKDKBH_02203 2.2e-25 K Helix-turn-helix domain
HMOKDKBH_02204 1.3e-20 XK27_07105 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02205 1.1e-29 K Helix-turn-helix domain
HMOKDKBH_02207 4.1e-09 S Arc-like DNA binding domain
HMOKDKBH_02209 4e-21 K Conserved phage C-terminus (Phg_2220_C)
HMOKDKBH_02210 2.6e-26 S Domain of unknown function (DUF771)
HMOKDKBH_02218 3.6e-34 S Phage derived protein Gp49-like (DUF891)
HMOKDKBH_02219 7.1e-35 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02221 1.1e-188 L N-6 DNA Methylase
HMOKDKBH_02222 2.2e-26 S Type I restriction modification DNA specificity domain
HMOKDKBH_02223 5.7e-11 S Single-strand binding protein family
HMOKDKBH_02226 1e-15 S Domain of Unknown Function with PDB structure (DUF3850)
HMOKDKBH_02228 2.5e-89 M Protein of unknown function (DUF3737)
HMOKDKBH_02229 9.9e-227 patB 4.4.1.8 E Aminotransferase, class I
HMOKDKBH_02230 7.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HMOKDKBH_02231 7.7e-67 S SdpI/YhfL protein family
HMOKDKBH_02232 7.5e-132 K Transcriptional regulatory protein, C terminal
HMOKDKBH_02233 7.2e-267 yclK 2.7.13.3, 4.6.1.1 T Histidine kinase
HMOKDKBH_02234 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HMOKDKBH_02235 1.1e-104 vanZ V VanZ like family
HMOKDKBH_02236 3.2e-253 pgi 5.3.1.9 G Belongs to the GPI family
HMOKDKBH_02237 4.9e-217 EGP Major facilitator Superfamily
HMOKDKBH_02238 1.7e-195 ampC V Beta-lactamase
HMOKDKBH_02241 8.4e-262 murF 6.3.2.10, 6.3.2.13 M Domain of unknown function (DUF1727)
HMOKDKBH_02242 1.7e-113 tdk 2.7.1.21 F thymidine kinase
HMOKDKBH_02243 3.1e-182 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMOKDKBH_02244 7.3e-155 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HMOKDKBH_02245 1.9e-189 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HMOKDKBH_02246 6.8e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HMOKDKBH_02247 1e-128 atpB C it plays a direct role in the translocation of protons across the membrane
HMOKDKBH_02248 3.5e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMOKDKBH_02249 4.4e-46 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMOKDKBH_02250 1.3e-91 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMOKDKBH_02251 2.5e-283 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMOKDKBH_02252 8.9e-173 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMOKDKBH_02253 3.3e-240 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMOKDKBH_02254 9e-72 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HMOKDKBH_02255 2e-30 ywzB S Protein of unknown function (DUF1146)
HMOKDKBH_02256 1.2e-177 mbl D Cell shape determining protein MreB Mrl
HMOKDKBH_02257 1e-50 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HMOKDKBH_02258 3.3e-33 S Protein of unknown function (DUF2969)
HMOKDKBH_02259 4.7e-216 rodA D Belongs to the SEDS family
HMOKDKBH_02260 1.8e-78 usp6 T universal stress protein
HMOKDKBH_02261 8.4e-39
HMOKDKBH_02262 6.3e-238 rarA L recombination factor protein RarA
HMOKDKBH_02263 1.3e-84 yueI S Protein of unknown function (DUF1694)
HMOKDKBH_02264 1.4e-110 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMOKDKBH_02265 2.1e-294 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HMOKDKBH_02266 4.8e-213 iscS2 2.8.1.7 E Aminotransferase class V
HMOKDKBH_02267 2e-225 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMOKDKBH_02268 1.7e-184 3.6.4.12 K Putative ATP-dependent DNA helicase recG C-terminal
HMOKDKBH_02269 3.2e-119 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMOKDKBH_02270 5.5e-44 3.6.4.12 S PD-(D/E)XK nuclease family transposase
HMOKDKBH_02271 2.1e-65 2.4.1.83 GT2 S GtrA-like protein
HMOKDKBH_02272 5.2e-170 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
HMOKDKBH_02273 1.5e-94 S Protein of unknown function (DUF3990)
HMOKDKBH_02274 6.5e-44
HMOKDKBH_02276 0.0 3.6.3.8 P P-type ATPase
HMOKDKBH_02277 1.1e-132 S AAA domain, putative AbiEii toxin, Type IV TA system
HMOKDKBH_02278 2.5e-52
HMOKDKBH_02279 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HMOKDKBH_02280 1.5e-239 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HMOKDKBH_02281 5.7e-126 S Haloacid dehalogenase-like hydrolase
HMOKDKBH_02282 2.3e-108 radC L DNA repair protein
HMOKDKBH_02283 2.4e-176 mreB D cell shape determining protein MreB
HMOKDKBH_02284 2e-147 mreC M Involved in formation and maintenance of cell shape
HMOKDKBH_02285 2.7e-94 mreD
HMOKDKBH_02287 6.4e-54 S Protein of unknown function (DUF3397)
HMOKDKBH_02288 6.3e-78 mraZ K Belongs to the MraZ family
HMOKDKBH_02289 7.2e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HMOKDKBH_02290 1.8e-54 ftsL D Cell division protein FtsL
HMOKDKBH_02291 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HMOKDKBH_02292 1.5e-175 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMOKDKBH_02293 5e-262 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMOKDKBH_02294 3.7e-207 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMOKDKBH_02295 4.5e-152 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HMOKDKBH_02296 1.3e-246 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HMOKDKBH_02297 1.7e-206 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMOKDKBH_02298 7.3e-74 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HMOKDKBH_02299 1.7e-45 yggT S YGGT family
HMOKDKBH_02300 5.7e-149 ylmH S S4 domain protein
HMOKDKBH_02301 2.8e-74 gpsB D DivIVA domain protein
HMOKDKBH_02302 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMOKDKBH_02303 3.6e-31 cspA K 'Cold-shock' DNA-binding domain
HMOKDKBH_02304 2.8e-102 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HMOKDKBH_02305 6.7e-37
HMOKDKBH_02306 1.2e-126 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HMOKDKBH_02307 3.2e-217 iscS 2.8.1.7 E Aminotransferase class V
HMOKDKBH_02308 5.4e-56 XK27_04120 S Putative amino acid metabolism
HMOKDKBH_02309 5.1e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HMOKDKBH_02310 3.9e-127 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase family
HMOKDKBH_02311 8.3e-106 S Repeat protein
HMOKDKBH_02312 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HMOKDKBH_02313 1.6e-294 L Nuclease-related domain
HMOKDKBH_02314 2.3e-164 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HMOKDKBH_02315 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMOKDKBH_02316 3.5e-32 ykzG S Belongs to the UPF0356 family
HMOKDKBH_02317 8.9e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HMOKDKBH_02318 0.0 typA T GTP-binding protein TypA
HMOKDKBH_02319 5.9e-211 ftsW D Belongs to the SEDS family
HMOKDKBH_02320 5.1e-54 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HMOKDKBH_02321 4.5e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HMOKDKBH_02322 3.6e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMOKDKBH_02323 2.4e-187 ylbL T Belongs to the peptidase S16 family
HMOKDKBH_02324 3.1e-79 comEA L Competence protein ComEA
HMOKDKBH_02325 0.0 comEC S Competence protein ComEC
HMOKDKBH_02326 2.6e-175 holA 2.7.7.7 L DNA polymerase III delta subunit
HMOKDKBH_02327 2.6e-34 rpsT J Binds directly to 16S ribosomal RNA
HMOKDKBH_02328 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HMOKDKBH_02329 1.1e-309 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HMOKDKBH_02330 1.3e-148
HMOKDKBH_02331 1.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMOKDKBH_02332 5.8e-215 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HMOKDKBH_02333 2e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMOKDKBH_02334 1.4e-104 engB D Necessary for normal cell division and for the maintenance of normal septation
HMOKDKBH_02335 7.8e-39 yjeM E Amino Acid
HMOKDKBH_02336 3.4e-175 yjeM E Amino Acid
HMOKDKBH_02337 2.3e-192 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMOKDKBH_02338 1.3e-259 lysC 2.7.2.4 E Belongs to the aspartokinase family
HMOKDKBH_02339 1.3e-246 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HMOKDKBH_02340 2.8e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HMOKDKBH_02341 2e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HMOKDKBH_02342 9.8e-177 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMOKDKBH_02343 7e-144 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HMOKDKBH_02344 2.7e-216 aspC 2.6.1.1 E Aminotransferase
HMOKDKBH_02345 2.6e-197 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMOKDKBH_02346 2.1e-194 pbpX1 V Beta-lactamase
HMOKDKBH_02347 1.2e-299 I Protein of unknown function (DUF2974)
HMOKDKBH_02348 3.6e-39 C FMN_bind
HMOKDKBH_02349 1.5e-81
HMOKDKBH_02350 1.3e-176 iunH 3.2.2.1 F inosine-uridine preferring nucleoside hydrolase
HMOKDKBH_02351 2e-85 alkD L DNA alkylation repair enzyme
HMOKDKBH_02352 9.9e-293 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMOKDKBH_02353 6.4e-128 K UTRA domain
HMOKDKBH_02354 1e-54 celA1 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HMOKDKBH_02355 8.7e-60 chbA 2.7.1.196, 2.7.1.205 G PTS system, Lactose Cellobiose specific IIA subunit
HMOKDKBH_02356 6.9e-72
HMOKDKBH_02357 7.9e-71 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_02358 2e-169 celD G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_02359 3.5e-70 S Domain of unknown function (DUF3284)
HMOKDKBH_02360 4.5e-301 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMOKDKBH_02361 3.7e-131 gmuR K UTRA
HMOKDKBH_02362 1.2e-225 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_02363 1.5e-31 lacE G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HMOKDKBH_02364 3.9e-46 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMOKDKBH_02365 1.5e-203 pbg6 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HMOKDKBH_02366 1.8e-73 C nitroreductase
HMOKDKBH_02367 5.1e-11 S Domain of unknown function (DUF4767)
HMOKDKBH_02368 1.5e-80
HMOKDKBH_02369 1.6e-73 marR K Transcriptional regulator, MarR family
HMOKDKBH_02370 1.3e-48 4.2.1.59 I 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HMOKDKBH_02371 1.1e-86 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMOKDKBH_02372 2.9e-38 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMOKDKBH_02373 2.1e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMOKDKBH_02374 1.7e-139 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HMOKDKBH_02375 2.9e-107 IQ reductase
HMOKDKBH_02376 4e-210 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HMOKDKBH_02377 2.2e-49 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HMOKDKBH_02378 9.2e-61 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HMOKDKBH_02379 9.6e-237 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HMOKDKBH_02380 3.3e-139 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HMOKDKBH_02381 1.1e-128 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HMOKDKBH_02382 1.9e-122 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HMOKDKBH_02383 3e-80 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HMOKDKBH_02384 1.2e-191 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMOKDKBH_02387 4.1e-158 xth 3.1.11.2 L exodeoxyribonuclease III
HMOKDKBH_02388 6.6e-273 E amino acid
HMOKDKBH_02389 0.0 L Helicase C-terminal domain protein
HMOKDKBH_02390 4.8e-205 pbpX1 V Beta-lactamase
HMOKDKBH_02391 5.1e-226 N Uncharacterized conserved protein (DUF2075)
HMOKDKBH_02392 1.4e-69 def2 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HMOKDKBH_02393 8.4e-56 S Domain of unknown function (DUF4767)
HMOKDKBH_02394 5.8e-244 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HMOKDKBH_02395 2.5e-147 yitS S Uncharacterised protein, DegV family COG1307
HMOKDKBH_02396 3.2e-101 3.6.1.27 I Acid phosphatase homologues
HMOKDKBH_02397 5.6e-191 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HMOKDKBH_02399 2e-178 MA20_14895 S Conserved hypothetical protein 698
HMOKDKBH_02400 1.1e-83 dps P Belongs to the Dps family
HMOKDKBH_02401 3.8e-20 1.3.5.4 C FAD dependent oxidoreductase
HMOKDKBH_02402 5.6e-101 yihX 3.1.3.10, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HMOKDKBH_02403 1.8e-58 S Putative adhesin
HMOKDKBH_02404 3.5e-71 yjaB 2.3.1.181 K Acetyltransferase (GNAT) domain
HMOKDKBH_02405 2e-234 mepA V MATE efflux family protein
HMOKDKBH_02406 8.9e-40 L Transposase and inactivated derivatives, IS30 family
HMOKDKBH_02407 5.8e-13 L Transposase and inactivated derivatives, IS30 family
HMOKDKBH_02408 2.4e-10 L Psort location Cytoplasmic, score
HMOKDKBH_02409 8.9e-92 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
HMOKDKBH_02410 6.2e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HMOKDKBH_02411 1.6e-221 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HMOKDKBH_02412 3.1e-107 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HMOKDKBH_02413 1.7e-201 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMOKDKBH_02414 2.2e-120 lsa S ABC transporter
HMOKDKBH_02415 2.7e-83 S Protein of unknown function (DUF1211)
HMOKDKBH_02416 3.1e-113 ltrA S Bacterial low temperature requirement A protein (LtrA)
HMOKDKBH_02417 2.8e-119 3.6.1.55 F NUDIX domain
HMOKDKBH_02418 3.9e-246 brnQ U Component of the transport system for branched-chain amino acids
HMOKDKBH_02419 0.0 L Plasmid pRiA4b ORF-3-like protein
HMOKDKBH_02420 1.3e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMOKDKBH_02421 2.5e-08 S Protein of unknown function (DUF3021)
HMOKDKBH_02422 9e-34 K Bacterial regulatory helix-turn-helix protein, lysR family
HMOKDKBH_02423 1.6e-47 L Transposase
HMOKDKBH_02425 4.2e-63 lmrB EGP Major facilitator Superfamily
HMOKDKBH_02426 2.9e-122 rbtT P Major Facilitator Superfamily
HMOKDKBH_02427 2.7e-202 XK27_00915 C Luciferase-like monooxygenase
HMOKDKBH_02428 2.5e-86 K GNAT family
HMOKDKBH_02429 1.4e-124 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
HMOKDKBH_02431 4.3e-36
HMOKDKBH_02432 6.2e-288 P ABC transporter
HMOKDKBH_02433 2.3e-07 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_02434 3.7e-263 V ABC-type multidrug transport system, ATPase and permease components
HMOKDKBH_02435 1.2e-250 yifK E Amino acid permease
HMOKDKBH_02436 1.3e-179 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMOKDKBH_02437 1.5e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HMOKDKBH_02438 0.0 aha1 P E1-E2 ATPase
HMOKDKBH_02439 2.4e-175 F DNA/RNA non-specific endonuclease
HMOKDKBH_02440 5.9e-160 metQ2 P Belongs to the nlpA lipoprotein family
HMOKDKBH_02441 2.6e-189 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMOKDKBH_02442 3.4e-73 metI P ABC transporter permease
HMOKDKBH_02443 9e-267 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HMOKDKBH_02444 1.9e-261 frdC 1.3.5.4 C FAD binding domain
HMOKDKBH_02445 3.1e-170 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HMOKDKBH_02446 3.5e-252 pepC 3.4.22.40 E Peptidase C1-like family
HMOKDKBH_02448 2e-10 isp2 L PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein
HMOKDKBH_02449 9.5e-82 XK27_04435 3.5.4.5 J FR47-like protein
HMOKDKBH_02450 1.4e-36 S Cytochrome B5
HMOKDKBH_02451 8.6e-167 arbZ I Phosphate acyltransferases
HMOKDKBH_02452 1.6e-182 arbY M Glycosyl transferase family 8
HMOKDKBH_02453 5e-184 arbY M Glycosyl transferase family 8
HMOKDKBH_02454 5e-156 arbx M Glycosyl transferase family 8
HMOKDKBH_02455 1.6e-148 arbV 2.3.1.51 I Acyl-transferase
HMOKDKBH_02457 4.9e-34
HMOKDKBH_02459 4.8e-131 K response regulator
HMOKDKBH_02460 2.2e-305 vicK 2.7.13.3 T Histidine kinase
HMOKDKBH_02461 1.6e-257 yycH S YycH protein
HMOKDKBH_02462 3.4e-149 yycI S YycH protein
HMOKDKBH_02463 4.1e-147 vicX 3.1.26.11 S domain protein
HMOKDKBH_02464 1.6e-161 htrA 3.4.21.107 O serine protease
HMOKDKBH_02465 1e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMOKDKBH_02466 1.3e-133 hxlA 6.2.1.3 H Aldolase/RraA
HMOKDKBH_02467 5.7e-272 P Sodium:sulfate symporter transmembrane region
HMOKDKBH_02468 1.7e-153 ydjP I Alpha/beta hydrolase family
HMOKDKBH_02469 6.9e-195 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
HMOKDKBH_02470 1.2e-43 citD C Covalent carrier of the coenzyme of citrate lyase
HMOKDKBH_02471 2.4e-167 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
HMOKDKBH_02472 2.1e-288 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
HMOKDKBH_02473 9.3e-72 yeaL S Protein of unknown function (DUF441)
HMOKDKBH_02474 3.5e-21
HMOKDKBH_02475 3.6e-146 cbiQ P cobalt transport
HMOKDKBH_02476 0.0 ykoD P ABC transporter, ATP-binding protein
HMOKDKBH_02477 1.5e-95 S UPF0397 protein
HMOKDKBH_02478 2.9e-66 S Domain of unknown function DUF1828
HMOKDKBH_02479 5.5e-09
HMOKDKBH_02480 1.5e-50
HMOKDKBH_02481 2.6e-177 citR K Putative sugar-binding domain
HMOKDKBH_02482 6.5e-249 yjjP S Putative threonine/serine exporter
HMOKDKBH_02484 5.9e-37 M domain protein
HMOKDKBH_02485 8.2e-85 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HMOKDKBH_02486 6.5e-176 prmA J Ribosomal protein L11 methyltransferase
HMOKDKBH_02487 8.5e-60
HMOKDKBH_02488 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMOKDKBH_02489 6e-76 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HMOKDKBH_02490 5.8e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
HMOKDKBH_02491 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HMOKDKBH_02492 1.2e-222 patA 2.6.1.1 E Aminotransferase
HMOKDKBH_02494 2.8e-216 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMOKDKBH_02495 4.8e-34 S reductase
HMOKDKBH_02496 4.4e-39 S reductase
HMOKDKBH_02497 2.7e-32 S reductase
HMOKDKBH_02498 1.3e-148 yxeH S hydrolase
HMOKDKBH_02499 6.8e-181 gyaR 1.1.1.26, 2.7.1.165 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HMOKDKBH_02500 1.1e-243 yfnA E Amino Acid
HMOKDKBH_02501 6.8e-110 dedA 3.1.3.1 S SNARE associated Golgi protein
HMOKDKBH_02502 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HMOKDKBH_02503 1.7e-243 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMOKDKBH_02504 1.3e-82 I Acyltransferase
HMOKDKBH_02505 5.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HMOKDKBH_02506 5.1e-142 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HMOKDKBH_02507 1.5e-34 yrvD S Lipopolysaccharide assembly protein A domain
HMOKDKBH_02508 1.3e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HMOKDKBH_02509 8.2e-136 sip L Belongs to the 'phage' integrase family
HMOKDKBH_02513 1.7e-29 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMOKDKBH_02514 1.8e-84 S N-acetylmuramoyl-L-alanine amidase activity
HMOKDKBH_02516 1.8e-10
HMOKDKBH_02517 2.8e-309 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HMOKDKBH_02518 2.3e-23 S Protein of unknown function (DUF2929)
HMOKDKBH_02519 0.0 dnaE 2.7.7.7 L DNA polymerase
HMOKDKBH_02520 3.3e-183 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HMOKDKBH_02521 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HMOKDKBH_02522 1e-167 cvfB S S1 domain
HMOKDKBH_02523 2.9e-165 xerD D recombinase XerD
HMOKDKBH_02524 2.6e-61 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMOKDKBH_02525 7.6e-132 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMOKDKBH_02526 4.1e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMOKDKBH_02527 3.1e-130 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HMOKDKBH_02528 2.2e-112 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HMOKDKBH_02529 2.7e-18 M Lysin motif
HMOKDKBH_02530 2.2e-114 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HMOKDKBH_02531 5.5e-212 rpsA 1.17.7.4 J Ribosomal protein S1
HMOKDKBH_02532 4.3e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HMOKDKBH_02533 2.3e-41 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HMOKDKBH_02534 5.6e-228 S Tetratricopeptide repeat protein
HMOKDKBH_02535 1.3e-237 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMOKDKBH_02536 4.5e-94 rimL J Acetyltransferase (GNAT) domain
HMOKDKBH_02537 9.7e-133 S Alpha/beta hydrolase family
HMOKDKBH_02538 5.9e-34 yxaM EGP Major facilitator Superfamily
HMOKDKBH_02539 2.9e-117 fbiB 6.3.2.12, 6.3.2.17, 6.3.2.31, 6.3.2.34 S F420-0:Gamma-glutamyl ligase
HMOKDKBH_02540 1e-79 S AAA domain
HMOKDKBH_02541 3.3e-61 3.6.1.55 F NUDIX domain
HMOKDKBH_02542 1.9e-138 2.4.2.3 F Phosphorylase superfamily
HMOKDKBH_02543 9e-144 2.4.2.3 F Phosphorylase superfamily
HMOKDKBH_02544 3.6e-151 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HMOKDKBH_02545 9.7e-65 yagE E amino acid
HMOKDKBH_02546 8.4e-128 yagE E Amino acid permease
HMOKDKBH_02547 4.3e-86 3.4.21.96 S SLAP domain
HMOKDKBH_02548 1.7e-104 L Belongs to the 'phage' integrase family
HMOKDKBH_02552 8.3e-103 3.4.21.88 K Peptidase S24-like
HMOKDKBH_02553 1.1e-13 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02559 7.6e-32 L Psort location Cytoplasmic, score
HMOKDKBH_02563 3.2e-85 L Belongs to the 'phage' integrase family
HMOKDKBH_02564 1.7e-80 2.1.1.72 V site-specific DNA-methyltransferase (adenine-specific) activity
HMOKDKBH_02565 8.4e-25 G Peptidase_C39 like family
HMOKDKBH_02566 2.8e-162 M NlpC/P60 family
HMOKDKBH_02567 6.5e-91 G Peptidase_C39 like family
HMOKDKBH_02568 1.8e-175 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HMOKDKBH_02569 2.8e-77 P Cobalt transport protein
HMOKDKBH_02570 4.8e-249 cbiO1 S ABC transporter, ATP-binding protein
HMOKDKBH_02571 7.9e-174 K helix_turn_helix, arabinose operon control protein
HMOKDKBH_02572 8.3e-157 htpX O Belongs to the peptidase M48B family
HMOKDKBH_02573 5.1e-96 lemA S LemA family
HMOKDKBH_02574 7.5e-192 ybiR P Citrate transporter
HMOKDKBH_02575 2e-70 S Iron-sulphur cluster biosynthesis
HMOKDKBH_02576 1.9e-309 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
HMOKDKBH_02577 1.2e-17
HMOKDKBH_02579 4e-22 S Bacteriophage holin of superfamily 6 (Holin_LLH)
HMOKDKBH_02580 1e-101 M hydrolase, family 25
HMOKDKBH_02581 6.2e-157 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HMOKDKBH_02582 1.1e-225 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HMOKDKBH_02583 1.2e-107 hlyIII S protein, hemolysin III
HMOKDKBH_02584 2e-144 DegV S Uncharacterised protein, DegV family COG1307
HMOKDKBH_02585 7.1e-36 yozE S Belongs to the UPF0346 family
HMOKDKBH_02586 1.1e-66 yjcE P NhaP-type Na H and K H
HMOKDKBH_02587 1.5e-40 yjcE P Sodium proton antiporter
HMOKDKBH_02588 1.9e-94 yjcE P Sodium proton antiporter
HMOKDKBH_02589 2.8e-154 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HMOKDKBH_02590 4.6e-132 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HMOKDKBH_02591 5.8e-152 dprA LU DNA protecting protein DprA
HMOKDKBH_02592 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMOKDKBH_02593 1.4e-248 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HMOKDKBH_02594 5e-141 xerC D Phage integrase, N-terminal SAM-like domain
HMOKDKBH_02595 1.9e-89 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMOKDKBH_02596 8.2e-236 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMOKDKBH_02597 4.8e-181 lacX 5.1.3.3 G Aldose 1-epimerase
HMOKDKBH_02598 1.4e-86 C Aldo keto reductase
HMOKDKBH_02599 3.8e-48 M LysM domain protein
HMOKDKBH_02600 2.9e-15 M LysM domain protein
HMOKDKBH_02601 3.1e-150 xerD L Phage integrase, N-terminal SAM-like domain
HMOKDKBH_02602 3e-66 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMOKDKBH_02603 1e-63 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HMOKDKBH_02604 5e-13 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMOKDKBH_02605 1.4e-115 mmuP E amino acid
HMOKDKBH_02606 1.4e-272 pepV 3.5.1.18 E dipeptidase PepV
HMOKDKBH_02607 6.3e-93 XK26_02160 C Pyridoxamine 5'-phosphate oxidase
HMOKDKBH_02608 1.7e-284 E Amino acid permease
HMOKDKBH_02609 0.0 yaaO 4.1.1.17, 4.1.1.19 E Orn/Lys/Arg decarboxylase, C-terminal domain
HMOKDKBH_02610 2.3e-245 ynbB 4.4.1.1 P aluminum resistance
HMOKDKBH_02611 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HMOKDKBH_02612 9.9e-82 C Flavodoxin
HMOKDKBH_02613 0.0 uvrA3 L excinuclease ABC, A subunit
HMOKDKBH_02614 1.1e-189 mmuM 1.5.1.20, 2.1.1.10 H homocysteine S-methyltransferase
HMOKDKBH_02615 2.1e-114 3.6.1.27 I Acid phosphatase homologues
HMOKDKBH_02616 1.7e-51 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HMOKDKBH_02617 1.4e-115 lacA 2.3.1.79 S Transferase hexapeptide repeat
HMOKDKBH_02618 9.3e-204 pbpX1 V Beta-lactamase
HMOKDKBH_02619 2.8e-98 pdxK 2.7.1.35 H Phosphomethylpyrimidine kinase
HMOKDKBH_02620 7.5e-95 S ECF-type riboflavin transporter, S component
HMOKDKBH_02621 1.3e-229 S Putative peptidoglycan binding domain
HMOKDKBH_02622 9e-83 K Acetyltransferase (GNAT) domain
HMOKDKBH_02623 1.7e-251 pepT2 3.4.11.14, 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HMOKDKBH_02624 2.5e-191 yrvN L AAA C-terminal domain
HMOKDKBH_02625 5.7e-65 spxA_2 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HMOKDKBH_02626 6.8e-153 treB G phosphotransferase system
HMOKDKBH_02627 4.5e-111 treB G phosphotransferase system
HMOKDKBH_02628 1.2e-100 treR K UTRA
HMOKDKBH_02629 1e-288 treC 3.2.1.93 GH13 G Alpha amylase, catalytic domain protein
HMOKDKBH_02630 5.7e-18
HMOKDKBH_02631 6.7e-184 G Bacterial extracellular solute-binding protein
HMOKDKBH_02632 2.8e-176 sip L Belongs to the 'phage' integrase family
HMOKDKBH_02636 3.2e-13
HMOKDKBH_02640 1.3e-13
HMOKDKBH_02641 3e-59
HMOKDKBH_02643 2.8e-13 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02645 2e-20 cro K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02647 4.3e-90 S AntA/AntB antirepressor
HMOKDKBH_02652 7.2e-10
HMOKDKBH_02653 5e-07 K Helix-turn-helix XRE-family like proteins
HMOKDKBH_02655 7.7e-48
HMOKDKBH_02657 2.4e-59 S Protein of unknown function (DUF1071)
HMOKDKBH_02658 2.3e-33 S Conserved phage C-terminus (Phg_2220_C)
HMOKDKBH_02659 1.4e-51 dnaC L IstB-like ATP binding protein
HMOKDKBH_02665 3.5e-32 S VRR_NUC
HMOKDKBH_02667 7.1e-15
HMOKDKBH_02675 2.7e-35 S HicB_like antitoxin of bacterial toxin-antitoxin system
HMOKDKBH_02676 5.2e-10 hicA N HicA toxin of bacterial toxin-antitoxin,
HMOKDKBH_02677 1.5e-28 L Terminase small subunit
HMOKDKBH_02678 1.8e-230 S Terminase-like family
HMOKDKBH_02679 7e-142 S Protein of unknown function (DUF1073)
HMOKDKBH_02680 9.5e-96 S Phage Mu protein F like protein
HMOKDKBH_02682 2.2e-26 S HNH endonuclease
HMOKDKBH_02683 9.8e-16 S Lysin motif
HMOKDKBH_02684 2e-83 S Uncharacterized protein conserved in bacteria (DUF2213)
HMOKDKBH_02685 1.1e-59
HMOKDKBH_02686 4.6e-142 Z012_11565 S Uncharacterized protein conserved in bacteria (DUF2184)
HMOKDKBH_02687 2.3e-29 S Protein of unknown function (DUF4054)
HMOKDKBH_02688 2.6e-75
HMOKDKBH_02689 1.7e-45
HMOKDKBH_02690 8e-57
HMOKDKBH_02691 9.7e-153 Z012_02110 S Protein of unknown function (DUF3383)
HMOKDKBH_02692 4e-56
HMOKDKBH_02693 1.2e-26
HMOKDKBH_02695 0.0 3.4.14.13 M Phage tail tape measure protein TP901
HMOKDKBH_02696 2.7e-58 M LysM domain
HMOKDKBH_02697 1.6e-46
HMOKDKBH_02698 4.4e-104
HMOKDKBH_02699 2e-48
HMOKDKBH_02700 9.5e-33
HMOKDKBH_02701 5.9e-126 Z012_12235 S Baseplate J-like protein
HMOKDKBH_02702 1.8e-08
HMOKDKBH_02703 6.6e-34
HMOKDKBH_02705 2.8e-70 M Glycosyl hydrolases family 25
HMOKDKBH_02707 7.1e-19
HMOKDKBH_02708 1.9e-37 G Bacterial extracellular solute-binding protein
HMOKDKBH_02709 1e-60 pdxH S Pyridoxamine 5'-phosphate oxidase
HMOKDKBH_02710 1.1e-236 XK27_01810 S Calcineurin-like phosphoesterase
HMOKDKBH_02712 0.0 S SLAP domain
HMOKDKBH_02713 0.0 hsdR 3.1.21.3 L DEAD/DEAH box helicase
HMOKDKBH_02714 1.2e-164 S AAA domain, putative AbiEii toxin, Type IV TA system
HMOKDKBH_02715 3.4e-42 S RloB-like protein
HMOKDKBH_02716 1.9e-259 hsdM 2.1.1.72 V type I restriction-modification system
HMOKDKBH_02717 5.7e-99 3.1.21.3 V Type I restriction modification DNA specificity domain
HMOKDKBH_02718 1.2e-63 S SIR2-like domain
HMOKDKBH_02719 3.2e-10 S Domain of unknown function DUF87
HMOKDKBH_02720 1.7e-39 S Domain of unknown function DUF87
HMOKDKBH_02721 1.9e-110 F DNA/RNA non-specific endonuclease
HMOKDKBH_02722 2.7e-34 S YSIRK type signal peptide
HMOKDKBH_02724 5.5e-53
HMOKDKBH_02725 1.8e-285 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HMOKDKBH_02726 8e-79 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMOKDKBH_02727 9.6e-169 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HMOKDKBH_02728 1e-198 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HMOKDKBH_02729 0.0 carB1 6.3.5.5 F Carbamoyl-phosphate synthase
HMOKDKBH_02730 0.0 FbpA K Fibronectin-binding protein
HMOKDKBH_02731 1.1e-66
HMOKDKBH_02732 1.3e-159 degV S EDD domain protein, DegV family
HMOKDKBH_02733 1.1e-24 L Transposase
HMOKDKBH_02734 1.5e-304 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HMOKDKBH_02735 5.4e-203 xerS L Belongs to the 'phage' integrase family
HMOKDKBH_02736 4.1e-67
HMOKDKBH_02737 8e-111 XK27_00160 S Domain of unknown function (DUF5052)
HMOKDKBH_02738 5.8e-211 M Glycosyl hydrolases family 25

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)