ORF_ID e_value Gene_name EC_number CAZy COGs Description
MDMFAGMF_00004 8e-48 S calcium ion binding
MDMFAGMF_00006 1.3e-25
MDMFAGMF_00007 2.7e-14
MDMFAGMF_00008 1.3e-17 S sequence-specific DNA binding
MDMFAGMF_00009 3.3e-57 sip L Belongs to the 'phage' integrase family
MDMFAGMF_00015 1.1e-113 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
MDMFAGMF_00016 3.8e-276 lysP E amino acid
MDMFAGMF_00017 1.3e-09 2.3.1.128 J Acetyltransferase (GNAT) domain
MDMFAGMF_00018 8.8e-119 lssY 3.6.1.27 I phosphatase
MDMFAGMF_00019 2.1e-82 S Threonine/Serine exporter, ThrE
MDMFAGMF_00020 2.1e-129 thrE S Putative threonine/serine exporter
MDMFAGMF_00021 1e-30 cspC K Cold shock protein
MDMFAGMF_00022 1.6e-123 sirR K iron dependent repressor
MDMFAGMF_00023 1.7e-165 czcD P cation diffusion facilitator family transporter
MDMFAGMF_00024 5e-117 S membrane
MDMFAGMF_00025 2.2e-109 S VIT family
MDMFAGMF_00026 5.5e-83 usp1 T Belongs to the universal stress protein A family
MDMFAGMF_00027 3.9e-75 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_00028 1.3e-44 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_00029 1.7e-151 glnH ET ABC transporter
MDMFAGMF_00030 1e-108 gluC P ABC transporter permease
MDMFAGMF_00031 3.6e-109 glnP P ABC transporter permease
MDMFAGMF_00032 1.6e-219 S CAAX protease self-immunity
MDMFAGMF_00033 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDMFAGMF_00034 7.2e-56
MDMFAGMF_00035 5.2e-75 merR K MerR HTH family regulatory protein
MDMFAGMF_00036 1.1e-265 lmrB EGP Major facilitator Superfamily
MDMFAGMF_00037 1.1e-117 S Domain of unknown function (DUF4811)
MDMFAGMF_00038 1.9e-158 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
MDMFAGMF_00040 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDMFAGMF_00041 2.2e-93 thiJ 2.7.11.1, 3.5.1.124 S DJ-1/PfpI family
MDMFAGMF_00042 7.9e-185 I Alpha beta
MDMFAGMF_00043 3.7e-277 emrY EGP Major facilitator Superfamily
MDMFAGMF_00044 2.8e-117 ung2 3.2.2.27 L Uracil-DNA glycosylase
MDMFAGMF_00045 9.4e-253 yjjP S Putative threonine/serine exporter
MDMFAGMF_00046 3.9e-159 mleR K LysR family
MDMFAGMF_00047 1.1e-112 ydjP I Alpha/beta hydrolase family
MDMFAGMF_00048 3e-148 citG 2.4.2.52, 2.7.7.61 H 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A synthase
MDMFAGMF_00049 7.1e-273 citF 2.8.3.10 H Citrate (pro-3S)-lyase alpha chain
MDMFAGMF_00050 1.1e-159 citE 4.1.3.25, 4.1.3.34 G Belongs to the HpcH HpaI aldolase family
MDMFAGMF_00051 8.5e-42 citD C Covalent carrier of the coenzyme of citrate lyase
MDMFAGMF_00052 7.4e-149 citC 6.2.1.22 H Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
MDMFAGMF_00053 7.9e-176 mez_1 1.1.1.38 C Malic enzyme, NAD binding domain
MDMFAGMF_00054 4.7e-126 citR K sugar-binding domain protein
MDMFAGMF_00055 1.2e-165 citP P Sodium:sulfate symporter transmembrane region
MDMFAGMF_00056 9.7e-132 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDMFAGMF_00057 1.4e-267 frdC 1.3.5.4 C FAD binding domain
MDMFAGMF_00058 1.1e-259 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
MDMFAGMF_00059 3.1e-303 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
MDMFAGMF_00060 2.8e-157 mleR K LysR family
MDMFAGMF_00061 2.3e-110 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MDMFAGMF_00062 1.3e-204 adhA 1.1.1.1 C Zinc-binding alcohol dehydrogenase family protein
MDMFAGMF_00063 7.3e-294 L PFAM plasmid pRiA4b ORF-3 family protein
MDMFAGMF_00064 3.2e-169 L transposase, IS605 OrfB family
MDMFAGMF_00065 3.3e-261 S Uncharacterized protein conserved in bacteria (DUF2252)
MDMFAGMF_00068 3.4e-22
MDMFAGMF_00069 8.3e-201 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
MDMFAGMF_00070 6.7e-75
MDMFAGMF_00071 2.3e-221 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDMFAGMF_00072 3.8e-129 ponA V Beta-lactamase enzyme family
MDMFAGMF_00073 9.3e-138 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDMFAGMF_00074 8.4e-262 nox C NADH oxidase
MDMFAGMF_00075 2.3e-87 hmpT S ECF-type riboflavin transporter, S component
MDMFAGMF_00076 0.0 glpQ 3.1.4.46 C Membrane domain of glycerophosphoryl diester phosphodiesterase
MDMFAGMF_00077 2.5e-166 yvgN C Aldo keto reductase
MDMFAGMF_00078 1.1e-135 puuD S peptidase C26
MDMFAGMF_00079 9.6e-258 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MDMFAGMF_00080 1.1e-209 yfeO P Voltage gated chloride channel
MDMFAGMF_00081 1.5e-220 sptS 2.7.13.3 T Histidine kinase
MDMFAGMF_00082 4.2e-113 K response regulator
MDMFAGMF_00083 9.7e-88 2.7.6.5 T Region found in RelA / SpoT proteins
MDMFAGMF_00084 1e-71
MDMFAGMF_00085 5.4e-121 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
MDMFAGMF_00086 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
MDMFAGMF_00087 1.1e-256 malT G Major Facilitator
MDMFAGMF_00088 2.7e-216 phbA 2.3.1.9 I Belongs to the thiolase family
MDMFAGMF_00089 2.3e-173 malR K Transcriptional regulator, LacI family
MDMFAGMF_00090 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
MDMFAGMF_00091 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
MDMFAGMF_00092 2.8e-287 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDMFAGMF_00093 3.9e-107 wecD3 K PFAM GCN5-related N-acetyltransferase
MDMFAGMF_00095 7e-206 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
MDMFAGMF_00096 0.0 clpL O associated with various cellular activities
MDMFAGMF_00097 7.8e-32
MDMFAGMF_00098 2e-219 patA 2.6.1.1 E Aminotransferase
MDMFAGMF_00099 5.8e-175 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDMFAGMF_00100 8.5e-75 osmC O OsmC-like protein
MDMFAGMF_00102 2.1e-123 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
MDMFAGMF_00103 3.6e-85 K FR47-like protein
MDMFAGMF_00104 3e-54 L An automated process has identified a potential problem with this gene model
MDMFAGMF_00106 1.1e-256 S Putative peptidoglycan binding domain
MDMFAGMF_00107 7.3e-41
MDMFAGMF_00108 3.1e-218 bacI V MacB-like periplasmic core domain
MDMFAGMF_00109 7e-127 V ABC transporter
MDMFAGMF_00110 8.3e-143 bacG M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MDMFAGMF_00111 5.7e-258 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
MDMFAGMF_00112 2.3e-145 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDMFAGMF_00113 9.4e-149 E Glyoxalase-like domain
MDMFAGMF_00114 7.5e-155 glcU U sugar transport
MDMFAGMF_00115 4.9e-226 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
MDMFAGMF_00116 1.1e-95 S reductase
MDMFAGMF_00118 4.7e-88 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MDMFAGMF_00119 5.9e-180 ABC-SBP S ABC transporter
MDMFAGMF_00120 5.9e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
MDMFAGMF_00121 1.7e-219 htrA 3.4.21.107 O serine protease
MDMFAGMF_00122 1.2e-154 vicX 3.1.26.11 S domain protein
MDMFAGMF_00123 4.4e-152 yycI S YycH protein
MDMFAGMF_00124 2.4e-250 yycH S YycH protein
MDMFAGMF_00125 0.0 vicK 2.7.13.3 T Histidine kinase
MDMFAGMF_00126 4e-130 K response regulator
MDMFAGMF_00128 1.2e-310 lmrA 3.6.3.44 V ABC transporter
MDMFAGMF_00129 1.8e-72 K helix_turn_helix multiple antibiotic resistance protein
MDMFAGMF_00131 9.9e-100 K DNA-binding helix-turn-helix protein
MDMFAGMF_00132 1.3e-157 S Polyphosphate nucleotide phosphotransferase, PPK2 family
MDMFAGMF_00133 3.1e-61
MDMFAGMF_00134 1.1e-207 yttB EGP Major facilitator Superfamily
MDMFAGMF_00135 1.8e-235 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
MDMFAGMF_00136 9.9e-74 rplI J Binds to the 23S rRNA
MDMFAGMF_00137 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
MDMFAGMF_00138 1.6e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MDMFAGMF_00139 7.5e-79 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDMFAGMF_00140 1.2e-48 rpsF J Binds together with S18 to 16S ribosomal RNA
MDMFAGMF_00141 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDMFAGMF_00142 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MDMFAGMF_00143 3.2e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MDMFAGMF_00144 1.7e-34 yaaA S S4 domain protein YaaA
MDMFAGMF_00145 2.2e-207 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
MDMFAGMF_00146 2.2e-251 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MDMFAGMF_00147 3.4e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
MDMFAGMF_00148 2e-58 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
MDMFAGMF_00149 4.5e-130 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDMFAGMF_00150 2.1e-132 jag S R3H domain protein
MDMFAGMF_00151 7.3e-253 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MDMFAGMF_00152 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
MDMFAGMF_00153 0.0 asnB 6.3.5.4 E Asparagine synthase
MDMFAGMF_00154 1.1e-294 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MDMFAGMF_00155 6.4e-248 yxbA 6.3.1.12 S ATP-grasp enzyme
MDMFAGMF_00156 1.7e-113 lepB 3.4.21.89 U Belongs to the peptidase S26 family
MDMFAGMF_00157 8e-93 2.3.1.183 M Acetyltransferase GNAT family
MDMFAGMF_00158 1.2e-165 S reductase
MDMFAGMF_00159 3e-295 S amidohydrolase
MDMFAGMF_00160 1.6e-40 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
MDMFAGMF_00161 6.7e-84 V ABC transporter, ATP-binding protein
MDMFAGMF_00162 1.4e-34 CP ABC-2 family transporter protein
MDMFAGMF_00163 1.2e-08
MDMFAGMF_00164 9.3e-43 azlD E Branched-chain amino acid transport
MDMFAGMF_00165 1.1e-113 S Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49)
MDMFAGMF_00167 4.5e-123 yhiD S MgtC family
MDMFAGMF_00168 1.6e-94 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDMFAGMF_00169 1.3e-195 V Beta-lactamase
MDMFAGMF_00170 6.5e-64 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDMFAGMF_00171 1.9e-86 XK27_08850 J Aminoacyl-tRNA editing domain
MDMFAGMF_00172 1.2e-19 relB L Addiction module antitoxin, RelB DinJ family
MDMFAGMF_00173 1e-24
MDMFAGMF_00174 3.9e-26 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
MDMFAGMF_00175 1.1e-117 K LytTr DNA-binding domain
MDMFAGMF_00176 3.6e-190 2.7.13.3 T GHKL domain
MDMFAGMF_00181 4.5e-115 1.1.1.193, 3.5.4.26 H RibD C-terminal domain
MDMFAGMF_00182 1.7e-160 mleP3 S Membrane transport protein
MDMFAGMF_00183 2.8e-120 T Transcriptional regulatory protein, C terminal
MDMFAGMF_00184 1.6e-233 T GHKL domain
MDMFAGMF_00185 8.3e-106 S Peptidase propeptide and YPEB domain
MDMFAGMF_00186 3.3e-114 P nitric oxide dioxygenase activity
MDMFAGMF_00187 9.9e-09 1.1.1.100 S Enoyl-(Acyl carrier protein) reductase
MDMFAGMF_00188 2.4e-34 yphJ 4.1.1.44 S decarboxylase
MDMFAGMF_00190 8.3e-11 S Oxidoreductase, aldo keto reductase family protein
MDMFAGMF_00191 1.9e-83 C Flavodoxin
MDMFAGMF_00192 5.6e-66 K Transcriptional regulator
MDMFAGMF_00193 4.5e-82 lacA S transferase hexapeptide repeat
MDMFAGMF_00194 1.2e-129 S Alpha beta hydrolase
MDMFAGMF_00195 1.3e-153 tesE Q hydratase
MDMFAGMF_00196 3.8e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDMFAGMF_00197 1.1e-228 aadAT EK Aminotransferase, class I
MDMFAGMF_00198 3e-155 ypuA S Protein of unknown function (DUF1002)
MDMFAGMF_00199 5.2e-184 ansA 3.5.1.1 EJ L-asparaginase, type I
MDMFAGMF_00200 4.2e-89 dut S Protein conserved in bacteria
MDMFAGMF_00201 5.4e-176
MDMFAGMF_00202 4.8e-149
MDMFAGMF_00203 3.7e-51 S Iron-sulfur cluster assembly protein
MDMFAGMF_00204 4.7e-99 msrA 1.8.4.11, 1.8.4.12 C Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MDMFAGMF_00205 7.4e-155 P Belongs to the nlpA lipoprotein family
MDMFAGMF_00206 3.9e-12
MDMFAGMF_00207 2.2e-218 patA 2.6.1.1, 2.6.1.57 E Aminotransferase
MDMFAGMF_00208 2e-296 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MDMFAGMF_00209 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
MDMFAGMF_00210 3.3e-177 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MDMFAGMF_00211 5.9e-22 S Protein of unknown function (DUF3042)
MDMFAGMF_00212 3.4e-67 yqhL P Rhodanese-like protein
MDMFAGMF_00213 1.5e-183 glk 2.7.1.2 G Glucokinase
MDMFAGMF_00214 4.8e-35 yqgQ S Bacterial protein of unknown function (DUF910)
MDMFAGMF_00215 6.2e-109 gluP 3.4.21.105 S Peptidase, S54 family
MDMFAGMF_00216 1.3e-99 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MDMFAGMF_00217 4.2e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDMFAGMF_00218 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
MDMFAGMF_00219 0.0 S membrane
MDMFAGMF_00220 7.5e-70 yneR S Belongs to the HesB IscA family
MDMFAGMF_00221 1.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDMFAGMF_00222 2.5e-118 udk 2.7.1.48 F Cytidine monophosphokinase
MDMFAGMF_00223 3e-116 rlpA M PFAM NLP P60 protein
MDMFAGMF_00224 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDMFAGMF_00225 2.3e-198 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MDMFAGMF_00226 6.7e-59 yodB K Transcriptional regulator, HxlR family
MDMFAGMF_00227 1.8e-92 XK27_09705 6.1.1.14 S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDMFAGMF_00228 1.3e-145 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDMFAGMF_00229 7.7e-45 acyP 3.6.1.7 C Belongs to the acylphosphatase family
MDMFAGMF_00230 5.9e-169 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
MDMFAGMF_00231 9.3e-71 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
MDMFAGMF_00232 1.4e-232 V MatE
MDMFAGMF_00233 2.3e-268 yjeM E Amino Acid
MDMFAGMF_00234 3.1e-278 arlS 2.7.13.3 T Histidine kinase
MDMFAGMF_00235 1.5e-121 K response regulator
MDMFAGMF_00236 1.1e-28 rpmF J Belongs to the bacterial ribosomal protein bL32 family
MDMFAGMF_00237 2.9e-99 yceD S Uncharacterized ACR, COG1399
MDMFAGMF_00238 3.4e-208 ylbM S Belongs to the UPF0348 family
MDMFAGMF_00239 2.5e-135 yqeM Q Methyltransferase
MDMFAGMF_00240 4.9e-60 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
MDMFAGMF_00241 8.1e-111 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
MDMFAGMF_00242 1.8e-121 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MDMFAGMF_00243 1.9e-47 yhbY J RNA-binding protein
MDMFAGMF_00244 1.1e-217 yqeH S Ribosome biogenesis GTPase YqeH
MDMFAGMF_00245 1.4e-95 yqeG S HAD phosphatase, family IIIA
MDMFAGMF_00246 3.3e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MDMFAGMF_00247 2.3e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
MDMFAGMF_00248 3.7e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MDMFAGMF_00249 6.2e-171 dnaI L Primosomal protein DnaI
MDMFAGMF_00250 3e-206 dnaB L replication initiation and membrane attachment
MDMFAGMF_00251 4.3e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MDMFAGMF_00252 2.1e-100 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MDMFAGMF_00253 7.4e-160 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
MDMFAGMF_00254 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MDMFAGMF_00255 7.5e-118 yoaK S Protein of unknown function (DUF1275)
MDMFAGMF_00256 2.5e-119 ybhL S Belongs to the BI1 family
MDMFAGMF_00257 3.4e-252 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
MDMFAGMF_00258 1.6e-19 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
MDMFAGMF_00259 7e-48 yafQ S Bacterial toxin of type II toxin-antitoxin system, YafQ
MDMFAGMF_00260 2.5e-118 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
MDMFAGMF_00261 1.7e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
MDMFAGMF_00262 7.5e-58 ytzB S Small secreted protein
MDMFAGMF_00263 1.3e-168 glsA 3.5.1.2 E Belongs to the glutaminase family
MDMFAGMF_00264 3.1e-181 iolS C Aldo keto reductase
MDMFAGMF_00265 1.4e-252 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
MDMFAGMF_00266 7.1e-11 D nuclear chromosome segregation
MDMFAGMF_00267 0.0 M domain protein
MDMFAGMF_00268 4.8e-20
MDMFAGMF_00269 8.8e-187 ampC V Beta-lactamase
MDMFAGMF_00270 3.5e-238 arcA 3.5.3.6 E Arginine
MDMFAGMF_00271 2.7e-79 argR K Regulates arginine biosynthesis genes
MDMFAGMF_00272 7.5e-261 E Arginine ornithine antiporter
MDMFAGMF_00273 1e-222 arcD U Amino acid permease
MDMFAGMF_00274 2.3e-10
MDMFAGMF_00275 1.4e-135 cobQ S CobB/CobQ-like glutamine amidotransferase domain
MDMFAGMF_00276 3.4e-263 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
MDMFAGMF_00277 6e-108 tdk 2.7.1.21 F thymidine kinase
MDMFAGMF_00278 1.2e-194 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MDMFAGMF_00279 7.3e-166 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
MDMFAGMF_00280 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
MDMFAGMF_00281 3.2e-231 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MDMFAGMF_00282 6.6e-116 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MDMFAGMF_00283 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDMFAGMF_00284 1.7e-191 yibE S overlaps another CDS with the same product name
MDMFAGMF_00285 2e-130 yibF S overlaps another CDS with the same product name
MDMFAGMF_00286 5.9e-233 pyrP F Permease
MDMFAGMF_00287 3.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
MDMFAGMF_00288 1.5e-14 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDMFAGMF_00289 1.1e-57 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MDMFAGMF_00290 5.1e-93 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MDMFAGMF_00291 4e-284 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MDMFAGMF_00292 1.9e-164 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MDMFAGMF_00293 1.1e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MDMFAGMF_00294 1e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
MDMFAGMF_00295 1.3e-33 ywzB S Protein of unknown function (DUF1146)
MDMFAGMF_00296 7.5e-239 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDMFAGMF_00297 1.9e-178 mbl D Cell shape determining protein MreB Mrl
MDMFAGMF_00298 1e-31 S Protein of unknown function (DUF2969)
MDMFAGMF_00299 1.1e-220 rodA D Belongs to the SEDS family
MDMFAGMF_00300 1.4e-47 gcvH E glycine cleavage
MDMFAGMF_00301 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
MDMFAGMF_00302 1.6e-149 2.3.1.19 K Helix-turn-helix XRE-family like proteins
MDMFAGMF_00303 2e-217 lacY G Oligosaccharide H symporter
MDMFAGMF_00304 1.1e-173 abf G Belongs to the glycosyl hydrolase 43 family
MDMFAGMF_00305 8.6e-146 K transcriptional regulator, ArsR family
MDMFAGMF_00306 1.2e-261 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
MDMFAGMF_00307 0.0 araB 2.7.1.12, 2.7.1.16 G carbohydrate kinase FGGY
MDMFAGMF_00308 1.8e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
MDMFAGMF_00309 1.1e-283 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
MDMFAGMF_00310 4.7e-97 maa 2.3.1.79 S Maltose O-acetyltransferase
MDMFAGMF_00311 8.6e-156 ytbE 1.1.1.346 S Aldo keto reductase
MDMFAGMF_00312 1.7e-204 araR K Transcriptional regulator
MDMFAGMF_00313 4.3e-83 usp6 T universal stress protein
MDMFAGMF_00314 5.7e-46
MDMFAGMF_00315 3.2e-242 rarA L recombination factor protein RarA
MDMFAGMF_00316 3.5e-85 yueI S Protein of unknown function (DUF1694)
MDMFAGMF_00317 4.5e-21
MDMFAGMF_00318 0.0 UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_00319 4e-128 UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_00320 0.0 UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_00321 1.9e-158 metQ_4 P Belongs to the nlpA lipoprotein family
MDMFAGMF_00322 7.4e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
MDMFAGMF_00323 4.2e-124 O Zinc-dependent metalloprotease
MDMFAGMF_00324 1.9e-115 S Membrane
MDMFAGMF_00325 3.1e-195 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
MDMFAGMF_00326 5.8e-79 S Domain of unknown function (DUF4767)
MDMFAGMF_00327 4.3e-13
MDMFAGMF_00328 2.6e-203 cytX U Belongs to the purine-cytosine permease (2.A.39) family
MDMFAGMF_00329 6.6e-98 wecD3 K PFAM GCN5-related N-acetyltransferase
MDMFAGMF_00330 3.1e-167 P CorA-like Mg2+ transporter protein
MDMFAGMF_00333 3.5e-288 GT2,GT4 M family 8
MDMFAGMF_00334 2.1e-160 M family 8
MDMFAGMF_00335 1.2e-109 M family 8
MDMFAGMF_00337 9.8e-255 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
MDMFAGMF_00338 3.7e-290 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MDMFAGMF_00339 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDMFAGMF_00340 1.8e-164 asp3 S Accessory Sec secretory system ASP3
MDMFAGMF_00341 6.4e-287 asp2 3.4.11.5 S Accessory Sec system GspB-transporter
MDMFAGMF_00342 3.6e-285 M transferase activity, transferring glycosyl groups
MDMFAGMF_00343 1.5e-209 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
MDMFAGMF_00344 7.4e-49 cpsJ S glycosyl transferase family 2
MDMFAGMF_00345 1.1e-28 M Glycosyltransferase, group 2 family protein
MDMFAGMF_00346 2.4e-189 nss M transferase activity, transferring glycosyl groups
MDMFAGMF_00347 0.0 M LPXTG-motif cell wall anchor domain protein
MDMFAGMF_00348 0.0 trxB2 1.8.1.9 C Thioredoxin domain
MDMFAGMF_00349 2.1e-105 ahpC 1.11.1.15 O Peroxiredoxin
MDMFAGMF_00350 3.1e-140 sdaAA 4.3.1.17 E L-serine dehydratase, iron-sulfur-dependent, alpha subunit
MDMFAGMF_00351 2.4e-121 sdaAB 4.3.1.17 E Serine dehydratase beta chain
MDMFAGMF_00353 7e-43 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDMFAGMF_00354 3.5e-165 T Calcineurin-like phosphoesterase superfamily domain
MDMFAGMF_00355 1.8e-223 mdtG EGP Major facilitator Superfamily
MDMFAGMF_00356 1.2e-129 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
MDMFAGMF_00357 4.4e-158 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
MDMFAGMF_00358 2.1e-177 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDMFAGMF_00359 0.0 lacZ 3.2.1.23 G -beta-galactosidase
MDMFAGMF_00360 8.2e-304 lacS G Transporter
MDMFAGMF_00361 1.9e-79 Q Methyltransferase
MDMFAGMF_00362 1.4e-116 ktrA P domain protein
MDMFAGMF_00363 3.2e-237 ktrB P Potassium uptake protein
MDMFAGMF_00364 0.0 mycA 4.2.1.53 S Myosin-crossreactive antigen
MDMFAGMF_00365 2.5e-138 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
MDMFAGMF_00366 1e-220 G Glycosyl hydrolases family 8
MDMFAGMF_00367 1.9e-242 ydaM M Glycosyl transferase
MDMFAGMF_00368 1.2e-136
MDMFAGMF_00369 3.9e-125 phoU P Plays a role in the regulation of phosphate uptake
MDMFAGMF_00370 1.1e-136 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
MDMFAGMF_00371 6.5e-154 pstA P Phosphate transport system permease protein PstA
MDMFAGMF_00372 6.6e-154 pstC P probably responsible for the translocation of the substrate across the membrane
MDMFAGMF_00373 1.6e-160 pstS P Phosphate
MDMFAGMF_00374 3.5e-134 K Transcriptional regulatory protein, C-terminal domain protein
MDMFAGMF_00375 8.6e-136 cbiO P ABC transporter
MDMFAGMF_00376 6.5e-135 P Cobalt transport protein
MDMFAGMF_00377 8.2e-185 nikMN P PDGLE domain
MDMFAGMF_00378 3.2e-166 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MDMFAGMF_00379 3.6e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MDMFAGMF_00380 1.9e-132 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
MDMFAGMF_00381 8.6e-78 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MDMFAGMF_00382 0.0 ureC 3.5.1.5 E Amidohydrolase family
MDMFAGMF_00383 2.1e-69 ureB 3.5.1.5 E Urease beta subunit
MDMFAGMF_00384 3.7e-48 ureA 3.5.1.5 E Urease, gamma subunit
MDMFAGMF_00385 5.6e-97 ureI S AmiS/UreI family transporter
MDMFAGMF_00386 4e-223 P ammonium transporter
MDMFAGMF_00387 4.4e-17 K Transcriptional regulator, HxlR family
MDMFAGMF_00388 3.8e-182
MDMFAGMF_00389 4.4e-97 2.3.1.128 K acetyltransferase
MDMFAGMF_00390 1.2e-22 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDMFAGMF_00391 1.1e-107 manA 5.3.1.8 G mannose-6-phosphate isomerase
MDMFAGMF_00392 5.2e-159 K LysR substrate binding domain
MDMFAGMF_00393 1.6e-205 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
MDMFAGMF_00394 1.1e-64 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDMFAGMF_00395 4.3e-181
MDMFAGMF_00396 6.4e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MDMFAGMF_00397 4.6e-181 S Phosphotransferase system, EIIC
MDMFAGMF_00398 3.3e-73 infB UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_00399 8.6e-44 1.3.5.4 S FMN binding
MDMFAGMF_00400 5.4e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MDMFAGMF_00401 1.4e-265 yfnA E amino acid
MDMFAGMF_00402 2.4e-256 gabT 2.6.1.19 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MDMFAGMF_00404 1.8e-204 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
MDMFAGMF_00405 0.0 helD 3.6.4.12 L DNA helicase
MDMFAGMF_00406 2.2e-81 ndk 2.7.4.6 F Belongs to the NDK family
MDMFAGMF_00407 1.4e-181 hpaIM 2.1.1.72 L Belongs to the N(4) N(6)-methyltransferase family
MDMFAGMF_00408 2.9e-190 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDMFAGMF_00409 6e-166 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDMFAGMF_00410 7e-226 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
MDMFAGMF_00411 8e-174
MDMFAGMF_00412 2.6e-129 cobB K SIR2 family
MDMFAGMF_00414 6.9e-161 yunF F Protein of unknown function DUF72
MDMFAGMF_00415 0.0 metG 6.1.1.10 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MDMFAGMF_00416 2.4e-155 tatD L hydrolase, TatD family
MDMFAGMF_00417 1.5e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MDMFAGMF_00418 2.3e-159 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
MDMFAGMF_00419 2.6e-36 veg S Biofilm formation stimulator VEG
MDMFAGMF_00420 3.1e-161 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MDMFAGMF_00421 1.1e-164 znuA P Belongs to the bacterial solute-binding protein 9 family
MDMFAGMF_00422 1e-122 fhuC P ABC transporter
MDMFAGMF_00423 1.2e-127 znuB U ABC 3 transport family
MDMFAGMF_00424 6.9e-150 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
MDMFAGMF_00425 1.7e-241 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MDMFAGMF_00426 1.1e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDMFAGMF_00427 2.1e-49
MDMFAGMF_00428 3.9e-11 rarA L recombination factor protein RarA
MDMFAGMF_00429 8.1e-119 rarA L recombination factor protein RarA
MDMFAGMF_00430 1.8e-145 yxeH S hydrolase
MDMFAGMF_00431 3.6e-268 ywfO S HD domain protein
MDMFAGMF_00432 2.7e-154 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
MDMFAGMF_00433 5.2e-265 glnP P ABC transporter
MDMFAGMF_00434 1.4e-138 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_00435 1.2e-220 cycA E Amino acid permease
MDMFAGMF_00436 1e-218 nupG F Nucleoside transporter
MDMFAGMF_00437 1.7e-170 rihC 3.2.2.1 F Nucleoside
MDMFAGMF_00438 6.5e-162 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
MDMFAGMF_00439 3.3e-127 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
MDMFAGMF_00440 1.1e-149 noc K Belongs to the ParB family
MDMFAGMF_00441 1.4e-139 soj D Sporulation initiation inhibitor
MDMFAGMF_00442 1.3e-154 spo0J K Belongs to the ParB family
MDMFAGMF_00443 2e-31 yyzM S Bacterial protein of unknown function (DUF951)
MDMFAGMF_00444 8.8e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
MDMFAGMF_00445 4.2e-133 XK27_01040 S Protein of unknown function (DUF1129)
MDMFAGMF_00446 3.4e-118 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MDMFAGMF_00447 4.5e-235 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
MDMFAGMF_00448 2.7e-233 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
MDMFAGMF_00449 1.8e-130 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
MDMFAGMF_00450 5.6e-172 deoR K sugar-binding domain protein
MDMFAGMF_00451 4.1e-209 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
MDMFAGMF_00452 3.8e-125 K response regulator
MDMFAGMF_00453 1.6e-200 hpk31 2.7.13.3 T Histidine kinase
MDMFAGMF_00454 1.2e-134 azlC E AzlC protein
MDMFAGMF_00455 3.6e-52 azlD S branched-chain amino acid
MDMFAGMF_00456 2.8e-133 K LysR substrate binding domain
MDMFAGMF_00457 3.9e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
MDMFAGMF_00458 3.8e-243 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
MDMFAGMF_00459 1.2e-171 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
MDMFAGMF_00460 6e-129 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
MDMFAGMF_00461 6.7e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MDMFAGMF_00462 1.5e-115 thiE 2.5.1.3, 2.7.6.2, 5.4.2.6 S Haloacid dehalogenase-like hydrolase
MDMFAGMF_00463 7.4e-230 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
MDMFAGMF_00464 3e-174 K AI-2E family transporter
MDMFAGMF_00465 2.9e-227
MDMFAGMF_00466 4.3e-208 potD P ABC transporter
MDMFAGMF_00467 1.9e-139 potC P ABC transporter permease
MDMFAGMF_00468 2.9e-145 potB P ABC transporter permease
MDMFAGMF_00469 2e-205 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
MDMFAGMF_00470 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
MDMFAGMF_00471 1.5e-177 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
MDMFAGMF_00472 0.0 pacL 3.6.3.8 P P-type ATPase
MDMFAGMF_00473 2.6e-85 dps P Belongs to the Dps family
MDMFAGMF_00474 4.2e-256 yagE E amino acid
MDMFAGMF_00475 8.8e-116 gph 3.1.3.18 S HAD hydrolase, family IA, variant
MDMFAGMF_00476 5.5e-150 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDMFAGMF_00478 1.5e-24 S Domain of unknown function (DUF4767)
MDMFAGMF_00480 3.2e-181 yumC 1.18.1.2, 1.19.1.1, 1.8.1.9 C Ferredoxin--NADP reductase
MDMFAGMF_00481 3e-181 iunH2 3.2.2.1 F nucleoside hydrolase
MDMFAGMF_00482 2.1e-137 IQ KR domain
MDMFAGMF_00483 1.5e-133 S membrane transporter protein
MDMFAGMF_00484 2.1e-97 S ABC-type cobalt transport system, permease component
MDMFAGMF_00485 1.9e-248 cbiO1 S ABC transporter, ATP-binding protein
MDMFAGMF_00486 7.5e-115 P Cobalt transport protein
MDMFAGMF_00487 1.6e-52 yvlA
MDMFAGMF_00488 0.0 yjcE P Sodium proton antiporter
MDMFAGMF_00489 2.9e-52 ypaA S Protein of unknown function (DUF1304)
MDMFAGMF_00490 4.8e-190 D Alpha beta
MDMFAGMF_00491 1e-72 K Transcriptional regulator
MDMFAGMF_00492 2.2e-159
MDMFAGMF_00493 1.1e-133 1.6.5.5 C Zinc-binding dehydrogenase
MDMFAGMF_00494 5e-33 1.6.5.5 C Zinc-binding dehydrogenase
MDMFAGMF_00495 6.5e-257 G PTS system Galactitol-specific IIC component
MDMFAGMF_00496 3.1e-212 EGP Major facilitator Superfamily
MDMFAGMF_00497 4.4e-134 V ABC transporter
MDMFAGMF_00498 3.7e-107
MDMFAGMF_00499 5.2e-14
MDMFAGMF_00500 7.1e-63
MDMFAGMF_00501 2.5e-194 lplA 6.3.1.20 H Lipoate-protein ligase
MDMFAGMF_00502 5.1e-81 uspA T universal stress protein
MDMFAGMF_00503 0.0 tetP J elongation factor G
MDMFAGMF_00504 3.1e-167 GK ROK family
MDMFAGMF_00505 1.5e-242 brnQ U Component of the transport system for branched-chain amino acids
MDMFAGMF_00506 3.8e-139 aroD S Serine hydrolase (FSH1)
MDMFAGMF_00507 4.7e-244 yagE E amino acid
MDMFAGMF_00508 0.0 xfp 4.1.2.22, 4.1.2.9 G Phosphoketolase
MDMFAGMF_00509 1.6e-134 gntR K UbiC transcription regulator-associated domain protein
MDMFAGMF_00510 1e-87 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MDMFAGMF_00511 2.9e-284 pipD E Dipeptidase
MDMFAGMF_00512 0.0 yfiC V ABC transporter
MDMFAGMF_00513 1e-304 lmrA V ABC transporter, ATP-binding protein
MDMFAGMF_00514 2.4e-189 ldhA 1.1.1.28 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDMFAGMF_00515 5.4e-135 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
MDMFAGMF_00516 5.1e-154
MDMFAGMF_00517 1.3e-156 3.2.1.52 GH20 G Xylose isomerase domain protein TIM barrel
MDMFAGMF_00518 1.3e-172 S AI-2E family transporter
MDMFAGMF_00519 3.4e-132 XK27_07210 6.1.1.6 S B3 4 domain
MDMFAGMF_00520 8.7e-78 yybA 2.3.1.57 K Transcriptional regulator
MDMFAGMF_00521 3.6e-91 M1-874 K Domain of unknown function (DUF1836)
MDMFAGMF_00522 3.9e-90 1.14.14.47, 1.6.5.3, 1.6.99.3 GM epimerase
MDMFAGMF_00523 5.4e-153 ypdB V (ABC) transporter
MDMFAGMF_00524 2.3e-240 yhdP S Transporter associated domain
MDMFAGMF_00525 1.3e-84 nrdI F Belongs to the NrdI family
MDMFAGMF_00526 1.2e-73 S 3-demethylubiquinone-9 3-methyltransferase
MDMFAGMF_00527 1.7e-191 yeaN P Transporter, major facilitator family protein
MDMFAGMF_00528 7.5e-288 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
MDMFAGMF_00529 5.4e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MDMFAGMF_00530 2.7e-39
MDMFAGMF_00531 1.4e-286 lacS G Transporter
MDMFAGMF_00532 6.2e-79 uspA T universal stress protein
MDMFAGMF_00533 3.7e-79 K AsnC family
MDMFAGMF_00534 1.6e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
MDMFAGMF_00535 8.6e-97 dedA 3.1.3.1 S SNARE associated Golgi protein
MDMFAGMF_00536 1.8e-181 galR K Transcriptional regulator
MDMFAGMF_00537 7.1e-283 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
MDMFAGMF_00538 5e-226 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MDMFAGMF_00539 7.6e-180 celE 3.2.1.4 GH5,GH9 E GDSL-like Lipase/Acylhydrolase family
MDMFAGMF_00540 1.4e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
MDMFAGMF_00541 3.1e-92 yxkA S Phosphatidylethanolamine-binding protein
MDMFAGMF_00542 9.1e-36
MDMFAGMF_00543 3.5e-52
MDMFAGMF_00544 4.3e-203
MDMFAGMF_00545 9.8e-83 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
MDMFAGMF_00546 1.2e-135 pnuC H nicotinamide mononucleotide transporter
MDMFAGMF_00547 5.6e-155 ytbE 1.1.1.346 S Aldo keto reductase
MDMFAGMF_00548 1.2e-123 K response regulator
MDMFAGMF_00549 1.4e-181 T PhoQ Sensor
MDMFAGMF_00550 1.7e-134 macB2 V ABC transporter, ATP-binding protein
MDMFAGMF_00551 0.0 ysaB V FtsX-like permease family
MDMFAGMF_00552 2e-157 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to
MDMFAGMF_00553 1.7e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDMFAGMF_00554 3.6e-54 K helix_turn_helix, mercury resistance
MDMFAGMF_00555 1.9e-286 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDMFAGMF_00556 5.3e-196 EGP Major facilitator Superfamily
MDMFAGMF_00557 7.1e-89 ymdB S Macro domain protein
MDMFAGMF_00558 1.7e-111 K Helix-turn-helix domain
MDMFAGMF_00559 0.0 pepO 3.4.24.71 O Peptidase family M13
MDMFAGMF_00560 3.6e-48
MDMFAGMF_00561 6.7e-232 S Putative metallopeptidase domain
MDMFAGMF_00562 1.5e-206 3.1.3.1 S associated with various cellular activities
MDMFAGMF_00563 7.5e-120 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
MDMFAGMF_00564 5.8e-64 yeaO S Protein of unknown function, DUF488
MDMFAGMF_00566 2e-118 yrkL S Flavodoxin-like fold
MDMFAGMF_00567 4e-53
MDMFAGMF_00568 1.3e-17 S Domain of unknown function (DUF4767)
MDMFAGMF_00569 1.5e-135 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDMFAGMF_00570 6.3e-50
MDMFAGMF_00574 3.6e-13 K Helix-turn-helix domain
MDMFAGMF_00576 1.1e-203 nrnB S DHHA1 domain
MDMFAGMF_00577 1.9e-228 S Uncharacterized protein conserved in bacteria (DUF2325)
MDMFAGMF_00578 5.4e-248 brnQ U Component of the transport system for branched-chain amino acids
MDMFAGMF_00579 2.2e-105 NU mannosyl-glycoprotein
MDMFAGMF_00580 9.8e-146 S Putative ABC-transporter type IV
MDMFAGMF_00581 5.4e-273 S ABC transporter, ATP-binding protein
MDMFAGMF_00582 7e-08
MDMFAGMF_00583 5.3e-34 arsR K helix_turn_helix, Arsenical Resistance Operon Repressor
MDMFAGMF_00584 1.2e-32 arsB 1.20.4.1 P Sodium Bile acid symporter family
MDMFAGMF_00585 1.4e-14 L Transposase
MDMFAGMF_00586 1.1e-181 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
MDMFAGMF_00587 3.1e-161 rrmA 2.1.1.187 H Methyltransferase
MDMFAGMF_00588 4.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
MDMFAGMF_00589 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
MDMFAGMF_00590 1.2e-10 S Protein of unknown function (DUF4044)
MDMFAGMF_00591 1.7e-57
MDMFAGMF_00592 4.5e-76 mraZ K Belongs to the MraZ family
MDMFAGMF_00593 1.9e-175 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
MDMFAGMF_00594 1.5e-56 ftsL D Cell division protein FtsL
MDMFAGMF_00595 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
MDMFAGMF_00596 2.6e-180 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MDMFAGMF_00597 1.1e-261 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MDMFAGMF_00598 1.6e-202 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MDMFAGMF_00599 6.1e-141 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
MDMFAGMF_00600 2.9e-254 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
MDMFAGMF_00601 3.4e-225 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MDMFAGMF_00602 9.4e-71 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
MDMFAGMF_00603 3.2e-40 yggT S YGGT family
MDMFAGMF_00604 1.3e-145 ylmH S S4 domain protein
MDMFAGMF_00605 1.6e-36 divIVA D DivIVA domain protein
MDMFAGMF_00606 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MDMFAGMF_00607 4.2e-32 cspA K Cold shock protein
MDMFAGMF_00608 9.2e-98 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
MDMFAGMF_00610 8.5e-125 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MDMFAGMF_00611 9.2e-217 iscS 2.8.1.7 E Aminotransferase class V
MDMFAGMF_00612 2.2e-57 XK27_04120 S Putative amino acid metabolism
MDMFAGMF_00613 1.5e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
MDMFAGMF_00614 4.9e-122 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
MDMFAGMF_00615 9e-119 S Repeat protein
MDMFAGMF_00616 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
MDMFAGMF_00617 8.1e-174 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MDMFAGMF_00618 4.2e-149 xth 3.1.11.2 L exodeoxyribonuclease III
MDMFAGMF_00619 4.7e-235 preT 1.3.1.1 E Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster
MDMFAGMF_00620 5.3e-237 preA 1.3.1.1 C 4Fe-4S dicluster domain
MDMFAGMF_00621 2.4e-153 yeaE S Aldo keto
MDMFAGMF_00622 1e-75 hsp O Belongs to the small heat shock protein (HSP20) family
MDMFAGMF_00623 2.6e-280 dinB 2.7.7.7 L impB/mucB/samB family C-terminal domain
MDMFAGMF_00624 2.2e-78 S Psort location Cytoplasmic, score
MDMFAGMF_00625 6.1e-83 S Short repeat of unknown function (DUF308)
MDMFAGMF_00626 1e-23
MDMFAGMF_00627 4.4e-103 V VanZ like family
MDMFAGMF_00628 2.4e-232 cycA E Amino acid permease
MDMFAGMF_00629 1.3e-84 perR P Belongs to the Fur family
MDMFAGMF_00630 2.1e-258 EGP Major facilitator Superfamily
MDMFAGMF_00631 1.4e-95 tag 3.2.2.20 L glycosylase
MDMFAGMF_00632 1.9e-217 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MDMFAGMF_00633 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDMFAGMF_00634 1.3e-41
MDMFAGMF_00635 3.8e-256 ytgP S Polysaccharide biosynthesis protein
MDMFAGMF_00636 1e-151 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MDMFAGMF_00637 2.4e-275 pepV 3.5.1.18 E dipeptidase PepV
MDMFAGMF_00638 1.2e-85 uspA T Belongs to the universal stress protein A family
MDMFAGMF_00639 9.8e-178 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDMFAGMF_00640 5e-116 dck 2.7.1.74 F deoxynucleoside kinase
MDMFAGMF_00641 2.2e-113
MDMFAGMF_00642 2.8e-185 rbsR K Periplasmic binding proteins and sugar binding domain of LacI family
MDMFAGMF_00643 2e-161 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDMFAGMF_00644 1.8e-31
MDMFAGMF_00645 2e-115 S CAAX protease self-immunity
MDMFAGMF_00646 1.9e-43
MDMFAGMF_00648 5.5e-280 O Arylsulfotransferase (ASST)
MDMFAGMF_00649 4.7e-293 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
MDMFAGMF_00650 6.4e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MDMFAGMF_00651 1.5e-169 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MDMFAGMF_00652 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MDMFAGMF_00653 1.5e-97 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
MDMFAGMF_00654 1.1e-264 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
MDMFAGMF_00655 9.8e-67 yabR J RNA binding
MDMFAGMF_00656 5.6e-56 divIC D Septum formation initiator
MDMFAGMF_00657 2.1e-39 yabO J S4 domain protein
MDMFAGMF_00658 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MDMFAGMF_00659 4.3e-103 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
MDMFAGMF_00660 1.1e-113 S (CBS) domain
MDMFAGMF_00661 5.8e-146 tesE Q hydratase
MDMFAGMF_00662 8.9e-242 codA 3.5.4.1 F cytosine deaminase
MDMFAGMF_00663 8.9e-251 U Belongs to the purine-cytosine permease (2.A.39) family
MDMFAGMF_00664 3.2e-62 L Toxic component of a toxin-antitoxin (TA) module
MDMFAGMF_00665 4.8e-210 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MDMFAGMF_00666 6.5e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
MDMFAGMF_00668 9.4e-294 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDMFAGMF_00669 5.7e-233 dltB M MBOAT, membrane-bound O-acyltransferase family
MDMFAGMF_00670 2.8e-35 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
MDMFAGMF_00671 1.7e-251 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
MDMFAGMF_00672 0.0 2.7.7.6 M Peptidase family M23
MDMFAGMF_00673 5.9e-120 rfbP 2.7.8.6 M Bacterial sugar transferase
MDMFAGMF_00674 1.4e-175 yfdH 2.4.2.53 GT2 M Glycosyltransferase, group 2 family protein
MDMFAGMF_00675 3.1e-144 cps1D M Domain of unknown function (DUF4422)
MDMFAGMF_00676 5.3e-139 recX 2.4.1.337 GT4 S Regulatory protein RecX
MDMFAGMF_00677 6.5e-31
MDMFAGMF_00678 6.6e-34 S Protein of unknown function (DUF2922)
MDMFAGMF_00679 2.6e-150 yihY S Belongs to the UPF0761 family
MDMFAGMF_00680 2.4e-281 yjeM E Amino Acid
MDMFAGMF_00681 2.9e-257 E Arginine ornithine antiporter
MDMFAGMF_00682 1.2e-24 arcT 2.6.1.1 E Aminotransferase
MDMFAGMF_00683 7.4e-188 arcT 2.6.1.1 E Aminotransferase
MDMFAGMF_00684 1.7e-167 map 3.4.11.18 E Methionine Aminopeptidase
MDMFAGMF_00685 6.1e-79 fld C Flavodoxin
MDMFAGMF_00686 1.5e-74 gtcA S Teichoic acid glycosylation protein
MDMFAGMF_00687 4.4e-208 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDMFAGMF_00689 6.7e-232 yfmL L DEAD DEAH box helicase
MDMFAGMF_00690 4.5e-191 mocA S Oxidoreductase
MDMFAGMF_00691 9.1e-62 S Domain of unknown function (DUF4828)
MDMFAGMF_00692 9.6e-106 yvdD 3.2.2.10 S Belongs to the LOG family
MDMFAGMF_00693 3.5e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDMFAGMF_00694 1.4e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
MDMFAGMF_00695 1.2e-191 S Protein of unknown function (DUF3114)
MDMFAGMF_00696 1.6e-79 yjcF 3.5.4.33, 4.4.1.8 K protein acetylation
MDMFAGMF_00697 2.2e-120 ybhL S Belongs to the BI1 family
MDMFAGMF_00698 6.1e-200 yhjX P Major Facilitator Superfamily
MDMFAGMF_00700 1.8e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
MDMFAGMF_00701 1e-218 ecsB U ABC transporter
MDMFAGMF_00702 4.3e-135 ecsA V ABC transporter, ATP-binding protein
MDMFAGMF_00703 4.1e-77 hit FG histidine triad
MDMFAGMF_00705 1.9e-127 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
MDMFAGMF_00706 0.0 L AAA domain
MDMFAGMF_00707 2.4e-220 yhaO L Ser Thr phosphatase family protein
MDMFAGMF_00708 9.4e-38 yheA S Belongs to the UPF0342 family
MDMFAGMF_00709 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
MDMFAGMF_00710 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
MDMFAGMF_00711 2.4e-150 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDMFAGMF_00712 3e-165 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDMFAGMF_00714 3.3e-40
MDMFAGMF_00715 5.1e-43
MDMFAGMF_00716 4.5e-211 folP 2.5.1.15 H dihydropteroate synthase
MDMFAGMF_00717 2.7e-103 xtp 2.5.1.15, 3.6.1.66 F Ham1 family
MDMFAGMF_00718 1.1e-226 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDMFAGMF_00719 3.1e-104 folE 2.7.6.3, 3.5.4.16 F GTP cyclohydrolase 1
MDMFAGMF_00720 1.9e-89 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)
MDMFAGMF_00721 1e-54 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
MDMFAGMF_00723 2.4e-46 yrvD S Pfam:DUF1049
MDMFAGMF_00724 6.9e-150 3.1.3.102, 3.1.3.104 S hydrolase
MDMFAGMF_00725 3.1e-89 ntd 2.4.2.6 F Nucleoside
MDMFAGMF_00726 2e-18
MDMFAGMF_00727 4.2e-166 S Alpha/beta hydrolase of unknown function (DUF915)
MDMFAGMF_00728 6.2e-114 yviA S Protein of unknown function (DUF421)
MDMFAGMF_00729 1.9e-69 S Protein of unknown function (DUF3290)
MDMFAGMF_00730 6e-42 ybaN S Protein of unknown function (DUF454)
MDMFAGMF_00731 0.0 I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MDMFAGMF_00732 4.6e-157 endA V DNA/RNA non-specific endonuclease
MDMFAGMF_00733 3.9e-254 yifK E Amino acid permease
MDMFAGMF_00735 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
MDMFAGMF_00736 6.4e-232 N Uncharacterized conserved protein (DUF2075)
MDMFAGMF_00737 3.9e-122 S SNARE associated Golgi protein
MDMFAGMF_00738 0.0 uvrA3 L excinuclease ABC, A subunit
MDMFAGMF_00739 8.5e-54 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDMFAGMF_00740 5.4e-57 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MDMFAGMF_00741 8.3e-69 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
MDMFAGMF_00742 2.5e-144 S DUF218 domain
MDMFAGMF_00743 0.0 ubiB S ABC1 family
MDMFAGMF_00744 1.1e-245 yhdP S Transporter associated domain
MDMFAGMF_00745 2.1e-73 copY K Copper transport repressor CopY TcrY
MDMFAGMF_00746 2.4e-243 EGP Major facilitator Superfamily
MDMFAGMF_00747 7.1e-121 flp 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDMFAGMF_00748 6.9e-72
MDMFAGMF_00749 2.8e-174
MDMFAGMF_00750 8e-172 fecB P Periplasmic binding protein
MDMFAGMF_00751 1.7e-134 fecE 3.6.3.34 HP AAA domain, putative AbiEii toxin, Type IV TA system
MDMFAGMF_00752 1.2e-129 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MDMFAGMF_00753 3.9e-78 S Flavodoxin
MDMFAGMF_00754 3.1e-63 moaE 2.8.1.12 H MoaE protein
MDMFAGMF_00755 3.9e-32 moaD 2.8.1.12 H ThiS family
MDMFAGMF_00756 1.6e-216 narK P Transporter, major facilitator family protein
MDMFAGMF_00757 9e-143 hepT 2.5.1.30, 2.5.1.90 H geranyltranstransferase activity
MDMFAGMF_00758 3.3e-175
MDMFAGMF_00759 1.2e-18
MDMFAGMF_00760 4.9e-114 nreC K PFAM regulatory protein LuxR
MDMFAGMF_00761 2e-186 comP 2.7.13.3 F Sensor histidine kinase
MDMFAGMF_00762 7.4e-43
MDMFAGMF_00763 1.3e-94 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
MDMFAGMF_00764 2.8e-74 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
MDMFAGMF_00765 3.1e-223 moeA 2.10.1.1 H MoeA N-terminal region (domain I and II)
MDMFAGMF_00766 2.5e-78 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
MDMFAGMF_00767 1.7e-182 moeB 2.7.7.73, 2.7.7.80 H ThiF family
MDMFAGMF_00768 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
MDMFAGMF_00769 0.0 narH 1.7.5.1 C 4Fe-4S dicluster domain
MDMFAGMF_00770 1.6e-97 narJ C nitrate reductase molybdenum cofactor assembly chaperone
MDMFAGMF_00771 2.5e-129 narI 1.7.5.1 C Nitrate reductase
MDMFAGMF_00773 3.5e-271 pipD E Dipeptidase
MDMFAGMF_00774 0.0 yjbQ P TrkA C-terminal domain protein
MDMFAGMF_00775 2.7e-25 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
MDMFAGMF_00776 2.3e-292 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MDMFAGMF_00777 1.9e-89
MDMFAGMF_00778 2.8e-35
MDMFAGMF_00779 9.3e-62 K DNA-templated transcription, initiation
MDMFAGMF_00780 4.7e-20 K DNA-templated transcription, initiation
MDMFAGMF_00781 4.7e-126
MDMFAGMF_00782 9.7e-65 K Transcriptional regulator, HxlR family
MDMFAGMF_00783 2.4e-160 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDMFAGMF_00784 7.6e-131 epsB M biosynthesis protein
MDMFAGMF_00785 6.2e-105 ywqD 2.7.10.1 D Capsular exopolysaccharide family
MDMFAGMF_00786 2.6e-48 pglC M Bacterial sugar transferase
MDMFAGMF_00787 1.7e-88 GT4 G Glycosyl transferase 4-like
MDMFAGMF_00788 8.8e-67 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
MDMFAGMF_00789 4.9e-43 M Pfam:DUF1792
MDMFAGMF_00791 1.3e-72 cps2I S Psort location CytoplasmicMembrane, score
MDMFAGMF_00792 1.8e-35 M Glycosyltransferase sugar-binding region containing DXD motif
MDMFAGMF_00793 1.7e-30 2.7.8.12 M Glycosyltransferase, group 2 family protein
MDMFAGMF_00794 1e-27 epsJ1 M Glycosyltransferase like family 2
MDMFAGMF_00795 2.3e-47 S Glycosyltransferase like family 2
MDMFAGMF_00796 1.7e-43 D Domain of Unknown Function (DUF1542)
MDMFAGMF_00797 1.4e-249 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
MDMFAGMF_00798 4.4e-258 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
MDMFAGMF_00799 1.5e-158 htpX O Belongs to the peptidase M48B family
MDMFAGMF_00800 2e-92 lemA S LemA family
MDMFAGMF_00801 2e-85 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDMFAGMF_00802 1.1e-118 pgm3 G Belongs to the phosphoglycerate mutase family
MDMFAGMF_00803 2.9e-162 fba 4.1.2.13, 4.1.2.29 G Fructose-1,6-bisphosphate aldolase, class II
MDMFAGMF_00804 4.4e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDMFAGMF_00805 2.5e-124 srtA 3.4.22.70 M sortase family
MDMFAGMF_00806 5.7e-166 S Alpha/beta hydrolase of unknown function (DUF915)
MDMFAGMF_00807 2.2e-235 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
MDMFAGMF_00808 4.6e-41 rpmE2 J Ribosomal protein L31
MDMFAGMF_00809 5.2e-237 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MDMFAGMF_00810 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
MDMFAGMF_00811 8.7e-48 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
MDMFAGMF_00812 4.6e-67 ywiB S Domain of unknown function (DUF1934)
MDMFAGMF_00813 0.0 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDMFAGMF_00814 3.8e-144 rfbJ M Glycosyl transferase family 2
MDMFAGMF_00815 1.2e-169
MDMFAGMF_00816 5e-118
MDMFAGMF_00817 3e-23 cps3I G Acyltransferase family
MDMFAGMF_00818 8.2e-76 M Domain of unknown function (DUF4422)
MDMFAGMF_00819 1.3e-42 M biosynthesis protein
MDMFAGMF_00820 3.4e-97 cps3F
MDMFAGMF_00821 3.7e-99 M Glycosyltransferase like family 2
MDMFAGMF_00822 4e-112 S Glycosyltransferase like family 2
MDMFAGMF_00823 7.7e-76 rgpB GT2 M Glycosyl transferase family 2
MDMFAGMF_00824 5.3e-214 rfbX S Membrane protein involved in the export of O-antigen and teichoic acid
MDMFAGMF_00825 1.1e-217 glf 5.4.99.9 M UDP-galactopyranose mutase
MDMFAGMF_00826 0.0 ganB 3.2.1.89 G arabinogalactan
MDMFAGMF_00828 2.9e-179 xerC L Belongs to the 'phage' integrase family
MDMFAGMF_00829 3.1e-52 hsdS 2.1.1.72, 3.1.21.3 V Type I restriction modification DNA specificity domain
MDMFAGMF_00830 0.0 hsdR 3.1.21.3 V Subunit R is required for both nuclease and ATPase activities, but not for modification
MDMFAGMF_00831 1.7e-35 higA K addiction module antidote protein HigA
MDMFAGMF_00832 0.0 L PLD-like domain
MDMFAGMF_00834 1.9e-175 rihA 3.2.2.1 F Inosine-uridine preferring nucleoside hydrolase
MDMFAGMF_00835 3.5e-178 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MDMFAGMF_00836 1.3e-92 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
MDMFAGMF_00837 8e-224 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
MDMFAGMF_00838 1.3e-76 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
MDMFAGMF_00839 1.5e-103 T Ion transport 2 domain protein
MDMFAGMF_00840 0.0 S Bacterial membrane protein YfhO
MDMFAGMF_00841 1.8e-199 G Transporter, major facilitator family protein
MDMFAGMF_00842 3e-107 yvrI K sigma factor activity
MDMFAGMF_00843 4.2e-62 ydiI Q Thioesterase superfamily
MDMFAGMF_00844 6.5e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
MDMFAGMF_00845 5.7e-269 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
MDMFAGMF_00846 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
MDMFAGMF_00847 1.2e-31 feoA P FeoA domain
MDMFAGMF_00848 1.9e-144 sufC O FeS assembly ATPase SufC
MDMFAGMF_00849 4.6e-241 sufD O FeS assembly protein SufD
MDMFAGMF_00850 4e-234 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MDMFAGMF_00851 6.5e-81 nifU C SUF system FeS assembly protein, NifU family
MDMFAGMF_00852 3.6e-271 sufB O assembly protein SufB
MDMFAGMF_00853 2.8e-57 yitW S Iron-sulfur cluster assembly protein
MDMFAGMF_00854 1.6e-160 hipB K Helix-turn-helix
MDMFAGMF_00855 7e-113 nreC K PFAM regulatory protein LuxR
MDMFAGMF_00856 6e-38 S Cytochrome B5
MDMFAGMF_00857 7.1e-155 yitU 3.1.3.104 S hydrolase
MDMFAGMF_00858 3.8e-262 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
MDMFAGMF_00859 1.5e-147 f42a O Band 7 protein
MDMFAGMF_00860 0.0 lytS 2.7.13.3 T LytS YhcK-type transmembrane receptor domain protein
MDMFAGMF_00861 3.9e-128 lytT K response regulator receiver
MDMFAGMF_00862 1.9e-66 lrgA S LrgA family
MDMFAGMF_00863 1.7e-123 lrgB M LrgB-like family
MDMFAGMF_00864 4.6e-177 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDMFAGMF_00865 1.3e-170 scrK 2.7.1.2, 2.7.1.4 GK ROK family
MDMFAGMF_00866 4.4e-186 galR K Periplasmic binding protein-like domain
MDMFAGMF_00867 0.0 rafA 3.2.1.22 G alpha-galactosidase
MDMFAGMF_00868 7.1e-89 S Protein of unknown function (DUF1440)
MDMFAGMF_00869 1.7e-193 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
MDMFAGMF_00870 4.2e-214 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
MDMFAGMF_00871 1.6e-161 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
MDMFAGMF_00872 1.3e-171 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
MDMFAGMF_00873 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
MDMFAGMF_00874 1.5e-86 ypmB S Protein conserved in bacteria
MDMFAGMF_00875 3e-125 dnaD L DnaD domain protein
MDMFAGMF_00876 1.8e-162 EG EamA-like transporter family
MDMFAGMF_00877 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
MDMFAGMF_00878 4.4e-117 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
MDMFAGMF_00879 7.8e-100 ypsA S Belongs to the UPF0398 family
MDMFAGMF_00880 1.7e-44 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
MDMFAGMF_00881 7.7e-85 F Belongs to the NrdI family
MDMFAGMF_00882 5.6e-222 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
MDMFAGMF_00883 4.8e-101 L Belongs to the 'phage' integrase family
MDMFAGMF_00884 6.4e-43
MDMFAGMF_00887 2.4e-75
MDMFAGMF_00888 4.7e-30
MDMFAGMF_00890 1.7e-45 E Zn peptidase
MDMFAGMF_00891 1e-34 ps115 K Helix-turn-helix XRE-family like proteins
MDMFAGMF_00892 1.2e-13
MDMFAGMF_00897 6.8e-10
MDMFAGMF_00900 2.9e-59 L DnaD domain protein
MDMFAGMF_00902 3.7e-62
MDMFAGMF_00903 7.3e-114
MDMFAGMF_00906 3.1e-50 S ORF6C domain
MDMFAGMF_00910 1.2e-57
MDMFAGMF_00912 1.6e-21
MDMFAGMF_00913 6.9e-32
MDMFAGMF_00916 2.8e-18
MDMFAGMF_00918 5.1e-61 L HNH nucleases
MDMFAGMF_00919 1.7e-57 L Phage terminase, small subunit
MDMFAGMF_00920 9.3e-283 S overlaps another CDS with the same product name
MDMFAGMF_00922 2.1e-203 S Phage portal protein
MDMFAGMF_00923 8.3e-99 clpP 3.4.21.92 OU Belongs to the peptidase S14 family
MDMFAGMF_00924 8e-184 S Phage capsid family
MDMFAGMF_00925 1.1e-38 S Phage gp6-like head-tail connector protein
MDMFAGMF_00926 5.9e-08 S head-tail joining protein
MDMFAGMF_00927 1.3e-33 S exonuclease activity
MDMFAGMF_00928 1.5e-19 S Protein of unknown function (DUF806)
MDMFAGMF_00929 7.9e-82 S Phage tail tube protein
MDMFAGMF_00930 1.2e-13 S Phage tail assembly chaperone proteins, TAC
MDMFAGMF_00932 3.2e-236 M Phage tail tape measure protein TP901
MDMFAGMF_00933 8.9e-87 S Phage tail protein
MDMFAGMF_00934 2.7e-147 ydhO 3.4.14.13 M Prophage endopeptidase tail
MDMFAGMF_00935 1.2e-42 GT2,GT4 LM gp58-like protein
MDMFAGMF_00942 4.3e-32 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MDMFAGMF_00943 9.9e-152 lysA2 M Glycosyl hydrolases family 25
MDMFAGMF_00944 4.8e-16 3.1.26.12, 3.2.1.8 M Collagen triple helix repeat (20 copies)
MDMFAGMF_00947 1.8e-71 rnhA 3.1.26.4 L Ribonuclease HI
MDMFAGMF_00948 1.5e-65 esbA S Family of unknown function (DUF5322)
MDMFAGMF_00949 6.3e-73 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MDMFAGMF_00950 5.3e-175 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDMFAGMF_00951 4.5e-205 carA 6.3.5.5 F Belongs to the CarA family
MDMFAGMF_00952 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDMFAGMF_00953 0.0 FbpA K Fibronectin-binding protein
MDMFAGMF_00954 1.2e-160 degV S EDD domain protein, DegV family
MDMFAGMF_00955 1.8e-92
MDMFAGMF_00956 8.6e-119 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
MDMFAGMF_00957 6e-157 gspA M family 8
MDMFAGMF_00958 1.3e-159 S Alpha beta hydrolase
MDMFAGMF_00959 4.8e-96 K Acetyltransferase (GNAT) domain
MDMFAGMF_00960 2.8e-78 yphH S Cupin domain
MDMFAGMF_00961 5.8e-74 yeaL S UPF0756 membrane protein
MDMFAGMF_00962 1.5e-263 M ErfK YbiS YcfS YnhG
MDMFAGMF_00963 9.6e-08 bamA GM domain, Protein
MDMFAGMF_00964 0.0 bamA GM domain, Protein
MDMFAGMF_00965 9.3e-65 gntR1 K Transcriptional regulator, GntR family
MDMFAGMF_00966 4.7e-157 V ABC transporter, ATP-binding protein
MDMFAGMF_00967 1.8e-114
MDMFAGMF_00968 8e-142 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
MDMFAGMF_00969 1.7e-100 S Pfam:DUF3816
MDMFAGMF_00970 0.0 clpE O Belongs to the ClpA ClpB family
MDMFAGMF_00971 2.9e-27
MDMFAGMF_00972 2.7e-39 ptsH G phosphocarrier protein HPR
MDMFAGMF_00973 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MDMFAGMF_00974 6.1e-227 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
MDMFAGMF_00975 2.2e-198 cpoA GT4 M Glycosyltransferase, group 1 family protein
MDMFAGMF_00976 1.3e-179 mprF I Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MDMFAGMF_00977 9.7e-39 ykuJ S Protein of unknown function (DUF1797)
MDMFAGMF_00978 9e-147 S Protein of unknown function (DUF3800)
MDMFAGMF_00980 0.0 snf 2.7.11.1 KL domain protein
MDMFAGMF_00981 1.4e-141 ywqE 3.1.3.48 GM PHP domain protein
MDMFAGMF_00982 4.7e-176 M Glycosyl hydrolases family 25
MDMFAGMF_00983 4.9e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
MDMFAGMF_00984 0.0 sbcC L Putative exonuclease SbcCD, C subunit
MDMFAGMF_00985 1.7e-93 L nuclease
MDMFAGMF_00986 0.0 XK27_00340 3.1.3.5 F Belongs to the 5'-nucleotidase family
MDMFAGMF_00987 6.9e-69
MDMFAGMF_00988 1.7e-102 fic D Fic/DOC family
MDMFAGMF_00989 4.4e-121 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
MDMFAGMF_00990 4.4e-152 3.1.3.73 G Belongs to the phosphoglycerate mutase family
MDMFAGMF_00991 3.7e-30
MDMFAGMF_00992 3.1e-54
MDMFAGMF_00993 5.4e-25
MDMFAGMF_00994 6e-152 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDMFAGMF_00995 1.1e-144 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MDMFAGMF_00996 1.1e-62 rplQ J Ribosomal protein L17
MDMFAGMF_00997 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDMFAGMF_00998 2.3e-63 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MDMFAGMF_00999 4.7e-58 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MDMFAGMF_01000 1.4e-14 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
MDMFAGMF_01001 1.2e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MDMFAGMF_01002 8.1e-125 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
MDMFAGMF_01003 8.8e-240 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
MDMFAGMF_01004 8.9e-64 rplO J Binds to the 23S rRNA
MDMFAGMF_01005 2.9e-24 rpmD J Ribosomal protein L30
MDMFAGMF_01006 2.2e-85 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MDMFAGMF_01007 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MDMFAGMF_01008 4.6e-94 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MDMFAGMF_01009 1.3e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MDMFAGMF_01010 4e-29 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MDMFAGMF_01011 1.4e-95 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MDMFAGMF_01012 2.6e-49 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MDMFAGMF_01013 1.1e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MDMFAGMF_01014 5e-41 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MDMFAGMF_01015 8.4e-28 rpmC J Belongs to the universal ribosomal protein uL29 family
MDMFAGMF_01016 3.5e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MDMFAGMF_01017 6.1e-112 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MDMFAGMF_01018 2.8e-52 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MDMFAGMF_01019 1.4e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MDMFAGMF_01020 4.2e-150 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MDMFAGMF_01021 2.2e-45 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
MDMFAGMF_01022 5.5e-107 rplD J Forms part of the polypeptide exit tunnel
MDMFAGMF_01023 1.5e-118 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MDMFAGMF_01024 3.4e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
MDMFAGMF_01025 1.9e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MDMFAGMF_01026 3.1e-212 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MDMFAGMF_01027 5.2e-253 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MDMFAGMF_01028 5.3e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
MDMFAGMF_01029 1.4e-37 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDMFAGMF_01030 2e-126 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDMFAGMF_01031 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MDMFAGMF_01032 4.5e-277 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MDMFAGMF_01033 1.1e-192 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
MDMFAGMF_01034 4.4e-103 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MDMFAGMF_01035 6.2e-293 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
MDMFAGMF_01036 2e-241 purD 6.3.4.13 F Belongs to the GARS family
MDMFAGMF_01037 1e-130 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDMFAGMF_01038 2e-173
MDMFAGMF_01039 4.4e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MDMFAGMF_01040 1.7e-87 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MDMFAGMF_01041 1.2e-258 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDMFAGMF_01042 6.7e-187 yegS 2.7.1.107 G Lipid kinase
MDMFAGMF_01043 1.8e-275 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDMFAGMF_01044 5.9e-277 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
MDMFAGMF_01045 3.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MDMFAGMF_01046 1.2e-202 camS S sex pheromone
MDMFAGMF_01047 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MDMFAGMF_01048 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
MDMFAGMF_01049 1.6e-213 purK2 6.3.4.18 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MDMFAGMF_01050 4.6e-100 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
MDMFAGMF_01051 1e-113 acmC 3.2.1.96 NU mannosyl-glycoprotein
MDMFAGMF_01052 2.1e-140 IQ reductase
MDMFAGMF_01053 5.6e-65 rpsI J Belongs to the universal ribosomal protein uS9 family
MDMFAGMF_01054 1.6e-98 cadA P P-type ATPase
MDMFAGMF_01055 3.3e-165 cadA P P-type ATPase
MDMFAGMF_01056 6.6e-210 5.4.2.7 G Metalloenzyme superfamily
MDMFAGMF_01058 3.7e-154 1.6.5.2 GM NAD(P)H-binding
MDMFAGMF_01059 2e-74 K Transcriptional regulator
MDMFAGMF_01060 3.9e-162 proX M ABC transporter, substrate-binding protein, QAT family
MDMFAGMF_01061 1.4e-108 proWZ P ABC transporter permease
MDMFAGMF_01062 1.5e-138 proV E ABC transporter, ATP-binding protein
MDMFAGMF_01063 1.3e-95 proW P ABC transporter, permease protein
MDMFAGMF_01064 2.4e-77 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
MDMFAGMF_01065 2.7e-252 clcA P chloride
MDMFAGMF_01066 5.7e-219 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MDMFAGMF_01067 3.1e-103 metI P ABC transporter permease
MDMFAGMF_01068 1.9e-192 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MDMFAGMF_01069 2.2e-154 metQ1 P Belongs to the nlpA lipoprotein family
MDMFAGMF_01070 5.8e-169 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
MDMFAGMF_01071 2.2e-221 norA EGP Major facilitator Superfamily
MDMFAGMF_01072 1.4e-130 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDMFAGMF_01073 6.6e-125
MDMFAGMF_01074 6.5e-246 merA 1.16.1.1, 1.8.1.7 C Pyridine nucleotide-disulfide oxidoreductase
MDMFAGMF_01076 0.0 L Helicase C-terminal domain protein
MDMFAGMF_01077 3.6e-77 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I PAP2 superfamily
MDMFAGMF_01078 7.7e-177 S Aldo keto reductase
MDMFAGMF_01080 6.5e-142 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDMFAGMF_01081 4.5e-62 psiE S Phosphate-starvation-inducible E
MDMFAGMF_01082 2e-97 ydeN S Serine hydrolase
MDMFAGMF_01084 2e-183 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MDMFAGMF_01085 2.8e-255 nhaC C Na H antiporter NhaC
MDMFAGMF_01086 1.2e-38 S Cytochrome b5-like Heme/Steroid binding domain
MDMFAGMF_01087 2.8e-114 ywnB S NAD(P)H-binding
MDMFAGMF_01088 1.1e-36
MDMFAGMF_01089 1.7e-284 gtfA 2.4.1.7 GH13 G Sucrose glucosyltransferase
MDMFAGMF_01090 5.3e-215 uhpT EGP Major facilitator Superfamily
MDMFAGMF_01091 9.8e-255 ytjP 3.5.1.18 E Dipeptidase
MDMFAGMF_01092 5.7e-275 arcD S C4-dicarboxylate anaerobic carrier
MDMFAGMF_01093 7.4e-180 yfeX P Peroxidase
MDMFAGMF_01094 6.3e-170 lsa S ABC transporter
MDMFAGMF_01095 1.1e-135 I alpha/beta hydrolase fold
MDMFAGMF_01096 2.1e-180 MA20_14895 S Conserved hypothetical protein 698
MDMFAGMF_01097 1.1e-95 S NADPH-dependent FMN reductase
MDMFAGMF_01098 3e-170 mccA 2.5.1.134, 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
MDMFAGMF_01099 8e-179 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
MDMFAGMF_01100 3e-232 mntH P H( )-stimulated, divalent metal cation uptake system
MDMFAGMF_01101 1.4e-253 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MDMFAGMF_01102 8.8e-78
MDMFAGMF_01103 4.1e-95 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MDMFAGMF_01105 6.2e-114 K Transcriptional regulator, TetR family
MDMFAGMF_01106 3.9e-69
MDMFAGMF_01107 4e-268 tagE3 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
MDMFAGMF_01108 1.9e-275 tagE2 2.4.1.52 GT4 M Poly(Glycerol-phosphate) alpha-glucosyltransferase
MDMFAGMF_01109 1.1e-272 M domain protein
MDMFAGMF_01110 0.0 malL 3.2.1.10 GH13 G Alpha amylase, catalytic domain protein
MDMFAGMF_01111 4e-267 G Major Facilitator
MDMFAGMF_01112 5.5e-77 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDMFAGMF_01113 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MDMFAGMF_01114 1.2e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
MDMFAGMF_01115 3.9e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MDMFAGMF_01116 4e-119 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
MDMFAGMF_01117 3.7e-197 ykiI
MDMFAGMF_01118 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDMFAGMF_01119 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MDMFAGMF_01120 1.1e-109 K Bacterial regulatory proteins, tetR family
MDMFAGMF_01121 5e-227 EGP Sugar (and other) transporter
MDMFAGMF_01122 1.5e-253 yfnA E Amino Acid
MDMFAGMF_01123 4.9e-72 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
MDMFAGMF_01124 1.6e-100 gmk2 2.7.4.8 F Guanylate kinase
MDMFAGMF_01125 1.5e-82 zur P Belongs to the Fur family
MDMFAGMF_01126 1.2e-16 3.2.1.14 GH18
MDMFAGMF_01127 2.2e-151
MDMFAGMF_01128 9.8e-39 pspC KT positive regulation of macromolecule biosynthetic process
MDMFAGMF_01129 1.6e-94 K Transcriptional regulator (TetR family)
MDMFAGMF_01130 1.3e-219 V domain protein
MDMFAGMF_01131 2e-180 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDMFAGMF_01133 4.4e-31 S Transglycosylase associated protein
MDMFAGMF_01134 1.4e-10
MDMFAGMF_01135 2.4e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MDMFAGMF_01136 1.5e-126 3.1.3.73 G phosphoglycerate mutase
MDMFAGMF_01137 3.4e-115 dedA S SNARE associated Golgi protein
MDMFAGMF_01138 0.0 helD 3.6.4.12 L DNA helicase
MDMFAGMF_01139 2.8e-241 nox C NADH oxidase
MDMFAGMF_01140 7.2e-253 nox C NADH oxidase
MDMFAGMF_01141 3e-159 EG EamA-like transporter family
MDMFAGMF_01142 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDMFAGMF_01143 3.7e-176 coaA 2.7.1.33 F Pantothenic acid kinase
MDMFAGMF_01144 2e-219 S cog cog1373
MDMFAGMF_01146 1.6e-301 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
MDMFAGMF_01147 1.9e-113 mloB K Putative ATP-dependent DNA helicase recG C-terminal
MDMFAGMF_01150 7e-160 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
MDMFAGMF_01151 1.8e-43 hxlR K Transcriptional regulator, HxlR family
MDMFAGMF_01152 4.3e-158 spoU 2.1.1.185 J Methyltransferase
MDMFAGMF_01153 6e-100 ywlG S Belongs to the UPF0340 family
MDMFAGMF_01154 1.5e-195 EGP Major facilitator Superfamily
MDMFAGMF_01155 3e-113 M Lysin motif
MDMFAGMF_01156 1.2e-79
MDMFAGMF_01157 4.6e-79 L PFAM transposase IS200-family protein
MDMFAGMF_01158 2.2e-14 K Cro/C1-type HTH DNA-binding domain
MDMFAGMF_01160 3.7e-19
MDMFAGMF_01161 1e-263 dtpT U amino acid peptide transporter
MDMFAGMF_01162 2.2e-148 yjjH S Calcineurin-like phosphoesterase
MDMFAGMF_01165 1.8e-108
MDMFAGMF_01166 4.5e-250 EGP Major facilitator Superfamily
MDMFAGMF_01167 3.9e-301 aspT P Predicted Permease Membrane Region
MDMFAGMF_01168 8.8e-133 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
MDMFAGMF_01169 1.8e-127 gntR1 K UbiC transcription regulator-associated domain protein
MDMFAGMF_01170 4.2e-283 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDMFAGMF_01171 1.5e-152 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
MDMFAGMF_01172 0.0 yhgF K Tex-like protein N-terminal domain protein
MDMFAGMF_01173 1.1e-83 ydcK S Belongs to the SprT family
MDMFAGMF_01175 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
MDMFAGMF_01176 4.2e-183 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
MDMFAGMF_01177 0.0 S Bacterial membrane protein, YfhO
MDMFAGMF_01178 1.2e-134 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MDMFAGMF_01179 5.9e-168 I alpha/beta hydrolase fold
MDMFAGMF_01180 3e-212 metC 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
MDMFAGMF_01181 5.4e-119 tcyB E ABC transporter
MDMFAGMF_01182 3.1e-133 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_01183 2.4e-139 tcyA ET Belongs to the bacterial solute-binding protein 3 family
MDMFAGMF_01184 1.7e-267 pepC 3.4.22.40 E Peptidase C1-like family
MDMFAGMF_01185 8.4e-125 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MDMFAGMF_01186 3.8e-50 HA62_12640 S GCN5-related N-acetyl-transferase
MDMFAGMF_01187 1.6e-99 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
MDMFAGMF_01188 7.8e-255 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
MDMFAGMF_01189 9.5e-206 yacL S domain protein
MDMFAGMF_01190 1.9e-272 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
MDMFAGMF_01191 2.1e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MDMFAGMF_01192 3e-136 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MDMFAGMF_01193 1.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
MDMFAGMF_01194 1.4e-15 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
MDMFAGMF_01195 3.4e-97 nusG K Participates in transcription elongation, termination and antitermination
MDMFAGMF_01196 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MDMFAGMF_01197 3e-122 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
MDMFAGMF_01198 7e-228 aadAT EK Aminotransferase, class I
MDMFAGMF_01200 2.9e-243 M Glycosyl transferase family group 2
MDMFAGMF_01201 9e-209 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
MDMFAGMF_01202 1.7e-82 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MDMFAGMF_01203 3.2e-54 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
MDMFAGMF_01204 3.4e-48
MDMFAGMF_01206 7.7e-40 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
MDMFAGMF_01207 6.8e-56 K transcriptional regulator PadR family
MDMFAGMF_01208 2.4e-78 XK27_06920 S Protein of unknown function (DUF1700)
MDMFAGMF_01209 1.1e-136 S Putative adhesin
MDMFAGMF_01210 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
MDMFAGMF_01211 1.2e-199 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDMFAGMF_01212 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MDMFAGMF_01213 3.4e-35 nrdH O Glutaredoxin
MDMFAGMF_01214 3.5e-91 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
MDMFAGMF_01215 4.9e-305 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDMFAGMF_01216 7e-47 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MDMFAGMF_01217 3.3e-109 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MDMFAGMF_01218 9.7e-39 S Protein of unknown function (DUF2508)
MDMFAGMF_01219 1.5e-115 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MDMFAGMF_01220 1e-51 yaaQ S Cyclic-di-AMP receptor
MDMFAGMF_01221 1.5e-186 holB 2.7.7.7 L DNA polymerase III
MDMFAGMF_01222 1.6e-58 yabA L Involved in initiation control of chromosome replication
MDMFAGMF_01223 1.5e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MDMFAGMF_01224 1.1e-136 fat 3.1.2.21 I Acyl-ACP thioesterase
MDMFAGMF_01225 2e-280 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDMFAGMF_01226 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
MDMFAGMF_01227 8.1e-174 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
MDMFAGMF_01228 2.5e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
MDMFAGMF_01229 7.3e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
MDMFAGMF_01230 4.3e-103 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
MDMFAGMF_01231 1.2e-196 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MDMFAGMF_01232 2.1e-132 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MDMFAGMF_01233 1.1e-226 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MDMFAGMF_01234 2.9e-137 proB 2.7.2.11 F Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MDMFAGMF_01235 5.1e-142 mtnU 3.5.1.3 S Carbon-nitrogen hydrolase
MDMFAGMF_01236 1.5e-227 mtnE 2.6.1.83 E Aminotransferase
MDMFAGMF_01237 7.3e-183 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDMFAGMF_01238 0.0 XK27_08510 L Type III restriction protein res subunit
MDMFAGMF_01239 5.7e-52
MDMFAGMF_01240 1.5e-152 cylA V ABC transporter
MDMFAGMF_01241 3.7e-146 cylB V ABC-2 type transporter
MDMFAGMF_01242 1.4e-75 K LytTr DNA-binding domain
MDMFAGMF_01243 6.3e-61 S Protein of unknown function (DUF3021)
MDMFAGMF_01245 1e-167 L Plasmid pRiA4b ORF-3-like protein
MDMFAGMF_01246 2.5e-15 K DNA-binding transcription factor activity
MDMFAGMF_01247 1.4e-110 rcfA 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
MDMFAGMF_01248 7e-98 dps P Belongs to the Dps family
MDMFAGMF_01249 2.5e-36 copZ P PFAM Heavy metal transport detoxification protein
MDMFAGMF_01250 3.4e-298 cadA 3.6.3.3, 3.6.3.5 P E1-E2 ATPase
MDMFAGMF_01251 2.1e-58 K transcriptional regulator
MDMFAGMF_01252 5.1e-41 K transcriptional regulator
MDMFAGMF_01253 2.8e-120 fhaB M Rib/alpha-like repeat
MDMFAGMF_01254 3.8e-64 infB UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_01255 1.8e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MDMFAGMF_01257 4.9e-102 nqr 1.5.1.36 S reductase
MDMFAGMF_01258 1.6e-198 XK27_09615 S reductase
MDMFAGMF_01259 9.4e-180 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
MDMFAGMF_01260 2.6e-42 XK27_08510 L Type III restriction protein res subunit
MDMFAGMF_01261 6.2e-49 S PFAM Archaeal ATPase
MDMFAGMF_01262 2.3e-69 S PFAM Archaeal ATPase
MDMFAGMF_01263 6.4e-87 3.6.4.12 S PD-(D/E)XK nuclease family transposase
MDMFAGMF_01264 3e-207 amtB P ammonium transporter
MDMFAGMF_01265 1.1e-250 gor 1.8.1.7 C pyridine nucleotide-disulfide oxidoreductase
MDMFAGMF_01266 5.4e-78 yvbK 3.1.3.25 K GNAT family
MDMFAGMF_01267 1.3e-39
MDMFAGMF_01268 1.4e-124 pnb C nitroreductase
MDMFAGMF_01269 7.5e-29 XK27_00915 C Luciferase-like monooxygenase
MDMFAGMF_01270 8.8e-73 XK27_00915 C Luciferase-like monooxygenase
MDMFAGMF_01271 1.1e-31 XK27_00915 C Luciferase-like monooxygenase
MDMFAGMF_01272 6.8e-154 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
MDMFAGMF_01273 1.4e-67 S Protein of unknown function (DUF3021)
MDMFAGMF_01274 3.5e-76 K LytTr DNA-binding domain
MDMFAGMF_01275 7.7e-121 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDMFAGMF_01276 1.2e-64 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
MDMFAGMF_01277 6.7e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MDMFAGMF_01278 4.7e-216 patA 2.6.1.1 E Aminotransferase
MDMFAGMF_01279 4.7e-140 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
MDMFAGMF_01280 1.5e-172 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MDMFAGMF_01281 1.6e-221 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
MDMFAGMF_01282 1.3e-75 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
MDMFAGMF_01283 7.9e-249 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
MDMFAGMF_01284 2e-258 lysC 2.7.2.4 E Belongs to the aspartokinase family
MDMFAGMF_01285 9.9e-183 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MDMFAGMF_01286 1.9e-95 lytE M LysM domain protein
MDMFAGMF_01287 0.0 oppD EP Psort location Cytoplasmic, score
MDMFAGMF_01288 2.3e-41 lytE M LysM domain protein
MDMFAGMF_01289 2.3e-159 sufD O Uncharacterized protein family (UPF0051)
MDMFAGMF_01290 2e-111 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
MDMFAGMF_01291 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
MDMFAGMF_01292 7.2e-232 lmrB EGP Major facilitator Superfamily
MDMFAGMF_01293 1.9e-95 2.3.1.128 K Acetyltransferase (GNAT) domain
MDMFAGMF_01294 1.7e-265 argH 4.3.2.1 E argininosuccinate lyase
MDMFAGMF_01295 1.1e-236 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
MDMFAGMF_01296 4.9e-187 cbh 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
MDMFAGMF_01297 6.6e-70 yqeY S YqeY-like protein
MDMFAGMF_01298 1.2e-23 rpsU J Belongs to the bacterial ribosomal protein bS21 family
MDMFAGMF_01299 3.8e-263 glnPH2 P ABC transporter permease
MDMFAGMF_01300 3.4e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_01301 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
MDMFAGMF_01302 4e-169 yniA G Phosphotransferase enzyme family
MDMFAGMF_01309 5.3e-128 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
MDMFAGMF_01310 2.4e-136 accA 2.1.3.15, 6.4.1.2 I alpha subunit
MDMFAGMF_01311 2.9e-135 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MDMFAGMF_01312 1.5e-258 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
MDMFAGMF_01313 4.7e-57 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
MDMFAGMF_01315 3e-201 xerS L Belongs to the 'phage' integrase family
MDMFAGMF_01316 2.3e-156 rssA S Phospholipase, patatin family
MDMFAGMF_01317 3.2e-118 L Integrase
MDMFAGMF_01318 1.4e-151 EG EamA-like transporter family
MDMFAGMF_01319 3.7e-85 L Transposase
MDMFAGMF_01320 1.8e-76 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
MDMFAGMF_01321 2.7e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
MDMFAGMF_01322 1.4e-121 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
MDMFAGMF_01323 1.8e-200 coiA 3.6.4.12 S Competence protein
MDMFAGMF_01324 3.2e-264 pipD E Dipeptidase
MDMFAGMF_01325 6.9e-113 yjbH Q Thioredoxin
MDMFAGMF_01326 5.2e-116 yjbM 2.7.6.5 S RelA SpoT domain protein
MDMFAGMF_01327 6e-154 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MDMFAGMF_01328 1.9e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
MDMFAGMF_01329 5.3e-164 G Belongs to the carbohydrate kinase PfkB family
MDMFAGMF_01330 4.5e-255 F Belongs to the purine-cytosine permease (2.A.39) family
MDMFAGMF_01331 1.9e-200 yegU O ADP-ribosylglycohydrolase
MDMFAGMF_01332 6.1e-102 pncA Q Isochorismatase family
MDMFAGMF_01333 3.1e-270 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MDMFAGMF_01334 1.9e-132 3.6.1.13, 3.6.1.55 F NUDIX domain
MDMFAGMF_01335 7e-159 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
MDMFAGMF_01336 1.1e-95 ltrA_1 L PFAM RNA-directed DNA polymerase (Reverse transcriptase)
MDMFAGMF_01337 0.0 uup S ABC transporter, ATP-binding protein
MDMFAGMF_01338 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MDMFAGMF_01339 1.1e-43 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MDMFAGMF_01340 1.9e-292 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
MDMFAGMF_01341 1e-60 S Aminoacyl-tRNA editing domain
MDMFAGMF_01342 2.8e-304 ybeC E amino acid
MDMFAGMF_01343 0.0 ydaO E amino acid
MDMFAGMF_01344 2.7e-39
MDMFAGMF_01345 1.7e-67 rmaI K Transcriptional regulator
MDMFAGMF_01346 1.4e-156 EGP Major facilitator Superfamily
MDMFAGMF_01347 2e-37 EGP Major facilitator Superfamily
MDMFAGMF_01348 1.2e-109 yvyE 3.4.13.9 S YigZ family
MDMFAGMF_01349 8.1e-249 comFA L Helicase C-terminal domain protein
MDMFAGMF_01350 1.4e-119 comFC S Competence protein
MDMFAGMF_01351 3e-93 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MDMFAGMF_01352 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
MDMFAGMF_01353 1.7e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MDMFAGMF_01354 3.1e-32 KT PspC domain protein
MDMFAGMF_01355 4.9e-52 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
MDMFAGMF_01356 4.6e-177 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MDMFAGMF_01357 6.9e-158 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MDMFAGMF_01358 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
MDMFAGMF_01359 1.1e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
MDMFAGMF_01360 3.3e-135 yrjD S LUD domain
MDMFAGMF_01361 1.9e-286 lutB C 4Fe-4S dicluster domain
MDMFAGMF_01362 1.4e-158 lutA C Cysteine-rich domain
MDMFAGMF_01363 1e-173 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
MDMFAGMF_01364 6.5e-218 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
MDMFAGMF_01365 1.9e-161 aatB ET PFAM extracellular solute-binding protein, family 3
MDMFAGMF_01366 7.2e-89 ykhA 3.1.2.20 I Thioesterase superfamily
MDMFAGMF_01367 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
MDMFAGMF_01368 1.9e-115 yfbR S HD containing hydrolase-like enzyme
MDMFAGMF_01369 6.9e-14
MDMFAGMF_01370 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
MDMFAGMF_01371 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
MDMFAGMF_01372 2.4e-245 steT E amino acid
MDMFAGMF_01373 2.7e-160 rapZ S Displays ATPase and GTPase activities
MDMFAGMF_01374 6.5e-187 ybhK S Required for morphogenesis under gluconeogenic growth conditions
MDMFAGMF_01375 3.1e-170 whiA K May be required for sporulation
MDMFAGMF_01377 8.8e-15
MDMFAGMF_01378 7e-240 glpT G Major Facilitator Superfamily
MDMFAGMF_01379 2.1e-103 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
MDMFAGMF_01381 1.1e-189 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
MDMFAGMF_01382 2.4e-228 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
MDMFAGMF_01383 1.8e-141 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
MDMFAGMF_01384 4.2e-250 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
MDMFAGMF_01385 5.6e-245 yifK E Amino acid permease
MDMFAGMF_01386 8.1e-293 clcA P chloride
MDMFAGMF_01387 1.8e-34 secG U Preprotein translocase
MDMFAGMF_01388 1.2e-146 est 3.1.1.1 S Serine aminopeptidase, S33
MDMFAGMF_01389 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
MDMFAGMF_01390 5.5e-83 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
MDMFAGMF_01391 6.3e-105 yxjI
MDMFAGMF_01392 1.8e-135 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MDMFAGMF_01393 4.9e-179 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
MDMFAGMF_01394 5.9e-82 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
MDMFAGMF_01395 6.1e-88 K Acetyltransferase (GNAT) domain
MDMFAGMF_01396 1.4e-74 S PAS domain
MDMFAGMF_01397 3e-101 dnaQ 2.7.7.7 L DNA polymerase III
MDMFAGMF_01398 3.6e-168 murB 1.3.1.98 M Cell wall formation
MDMFAGMF_01399 2.7e-166 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MDMFAGMF_01400 3e-66 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
MDMFAGMF_01401 3.7e-249 fucP G Major Facilitator Superfamily
MDMFAGMF_01402 5e-151 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
MDMFAGMF_01403 7.6e-126 ybbR S YbbR-like protein
MDMFAGMF_01404 3.2e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MDMFAGMF_01405 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
MDMFAGMF_01406 5.6e-52
MDMFAGMF_01407 0.0 oatA I Acyltransferase
MDMFAGMF_01408 1.8e-78 K Transcriptional regulator
MDMFAGMF_01409 1.1e-147 XK27_02985 S Cof-like hydrolase
MDMFAGMF_01410 1.8e-78 lytE M Lysin motif
MDMFAGMF_01412 1.2e-134 K response regulator
MDMFAGMF_01413 3.1e-273 yclK 2.7.13.3 T Histidine kinase
MDMFAGMF_01414 2.8e-154 glcU U sugar transport
MDMFAGMF_01415 8.4e-100 lacA 2.3.1.79 S Transferase hexapeptide repeat
MDMFAGMF_01416 5e-262 pgi 5.3.1.9 G Belongs to the GPI family
MDMFAGMF_01417 5.1e-25
MDMFAGMF_01419 5.6e-32 xylB 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDMFAGMF_01420 4.7e-154 KT YcbB domain
MDMFAGMF_01421 2.6e-191 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MDMFAGMF_01422 9.5e-172 arcC 2.7.2.2 E Belongs to the carbamate kinase family
MDMFAGMF_01423 3.6e-163 EG EamA-like transporter family
MDMFAGMF_01424 2.9e-102 XK27_08875 O PFAM peptidase M10A and M12B, matrixin and adamalysin
MDMFAGMF_01425 7.9e-45 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDMFAGMF_01426 2.4e-49 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
MDMFAGMF_01427 0.0 copA 3.6.3.54 P P-type ATPase
MDMFAGMF_01428 4.1e-86
MDMFAGMF_01430 3.6e-57
MDMFAGMF_01437 1.7e-14 arpU S Phage transcriptional regulator, ArpU family
MDMFAGMF_01438 1e-41 S D5 N terminal like
MDMFAGMF_01439 5.1e-42 S D5 N terminal like
MDMFAGMF_01440 2.1e-47
MDMFAGMF_01442 2.5e-12
MDMFAGMF_01444 2e-20 S Helix-turn-helix domain
MDMFAGMF_01445 3.3e-11 dicA K Helix-turn-helix domain
MDMFAGMF_01446 3e-132 L Belongs to the 'phage' integrase family
MDMFAGMF_01447 4e-92
MDMFAGMF_01448 0.0 M NlpC/P60 family
MDMFAGMF_01449 9.6e-310 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MDMFAGMF_01450 9.9e-216 brpA K Cell envelope-like function transcriptional attenuator common domain protein
MDMFAGMF_01451 3.3e-163 yueF S AI-2E family transporter
MDMFAGMF_01452 2.9e-139 csd1 3.5.1.28 G domain, Protein
MDMFAGMF_01453 0.0 gtfC 2.4.1.5 GH13 G Glycosyl hydrolase family 70
MDMFAGMF_01454 6.2e-162 L hmm pf00665
MDMFAGMF_01455 5e-106 L hmm pf00665
MDMFAGMF_01456 1.5e-52 L Helix-turn-helix domain
MDMFAGMF_01457 0.0 sprD D Domain of Unknown Function (DUF1542)
MDMFAGMF_01458 1.9e-08
MDMFAGMF_01459 9.5e-43 L Belongs to the 'phage' integrase family
MDMFAGMF_01462 4.3e-10 S peptidoglycan catabolic process
MDMFAGMF_01464 9.2e-150 lysA2 M Glycosyl hydrolases family 25
MDMFAGMF_01465 4.8e-33 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MDMFAGMF_01471 2e-177 S Hydrolases of the alpha beta superfamily
MDMFAGMF_01472 2.1e-196 adhP 1.1.1.1 C alcohol dehydrogenase
MDMFAGMF_01473 4.4e-77 ctsR K Belongs to the CtsR family
MDMFAGMF_01474 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
MDMFAGMF_01475 9.9e-282 2.4.1.5 GH13 G Glycosyl hydrolase family 70
MDMFAGMF_01476 0.0 S SEC-C Motif Domain Protein
MDMFAGMF_01477 1.8e-50
MDMFAGMF_01478 5.1e-137 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
MDMFAGMF_01479 1.6e-146 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
MDMFAGMF_01480 3.6e-117 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
MDMFAGMF_01481 1.6e-227 clcA_2 P Chloride transporter, ClC family
MDMFAGMF_01482 0.0 malZ 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
MDMFAGMF_01483 7.9e-109 lssY 3.6.1.27 I Acid phosphatase homologues
MDMFAGMF_01485 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
MDMFAGMF_01486 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
MDMFAGMF_01487 4.5e-129 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
MDMFAGMF_01488 1.1e-208 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
MDMFAGMF_01489 5.2e-259 G Major Facilitator
MDMFAGMF_01490 6.5e-148 K Transcriptional regulator, LacI family
MDMFAGMF_01493 2.6e-112 K Transcriptional regulator
MDMFAGMF_01494 5.2e-50 rplU J This protein binds to 23S rRNA in the presence of protein L20
MDMFAGMF_01495 1.8e-53 ysxB J Cysteine protease Prp
MDMFAGMF_01496 1e-44 rpmA J Belongs to the bacterial ribosomal protein bL27 family
MDMFAGMF_01497 3.5e-205 L Belongs to the 'phage' integrase family
MDMFAGMF_01498 6.1e-46
MDMFAGMF_01499 3.9e-20
MDMFAGMF_01500 7.8e-39 E Zn peptidase
MDMFAGMF_01501 2.1e-52 K Cro/C1-type HTH DNA-binding domain
MDMFAGMF_01502 5.9e-26 K Helix-turn-helix XRE-family like proteins
MDMFAGMF_01503 6.2e-65 S DNA binding
MDMFAGMF_01506 2.6e-07 K Helix-turn-helix XRE-family like proteins
MDMFAGMF_01511 8.3e-43 S ERF superfamily
MDMFAGMF_01512 2.4e-92 S Putative HNHc nuclease
MDMFAGMF_01513 1.2e-43 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
MDMFAGMF_01514 4e-57 S calcium ion binding
MDMFAGMF_01515 5e-52 dnaC 3.4.21.53 L IstB-like ATP binding protein
MDMFAGMF_01524 5.6e-29 S HNH endonuclease
MDMFAGMF_01527 5.3e-24
MDMFAGMF_01528 7.9e-22 S Mazg nucleotide pyrophosphohydrolase
MDMFAGMF_01530 4.1e-29 rusA L Endodeoxyribonuclease RusA
MDMFAGMF_01532 1.5e-11
MDMFAGMF_01535 1.2e-19
MDMFAGMF_01536 3e-76 xtmA L Terminase small subunit
MDMFAGMF_01537 1.4e-189 S Terminase-like family
MDMFAGMF_01538 3.7e-183 S Phage portal protein, SPP1 Gp6-like
MDMFAGMF_01539 5.6e-91
MDMFAGMF_01541 2.3e-31 S Domain of unknown function (DUF4355)
MDMFAGMF_01542 1e-120
MDMFAGMF_01543 1.2e-18
MDMFAGMF_01544 6.7e-30
MDMFAGMF_01545 6.2e-49 Z012_02125
MDMFAGMF_01547 3.7e-23
MDMFAGMF_01548 5.9e-104 Z012_02110 S Protein of unknown function (DUF3383)
MDMFAGMF_01549 1.7e-37
MDMFAGMF_01550 2.2e-14
MDMFAGMF_01552 1.3e-28
MDMFAGMF_01553 7e-53 3.5.1.28 M LysM domain
MDMFAGMF_01554 6.7e-35
MDMFAGMF_01555 3.2e-89
MDMFAGMF_01556 4.3e-27
MDMFAGMF_01557 3.7e-09 S Protein of unknown function (DUF2634)
MDMFAGMF_01558 2.5e-119 Z012_12235 S Baseplate J-like protein
MDMFAGMF_01559 4.6e-23
MDMFAGMF_01560 4.6e-65 G cellulose 1,4-beta-cellobiosidase activity
MDMFAGMF_01563 2.7e-40
MDMFAGMF_01565 5.1e-25 S Bacteriophage holin of superfamily 6 (Holin_LLH)
MDMFAGMF_01566 8.3e-96 S N-acetylmuramoyl-L-alanine amidase activity
MDMFAGMF_01567 4.3e-132 yggS S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MDMFAGMF_01568 9.5e-200 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDMFAGMF_01569 7e-116 J 2'-5' RNA ligase superfamily
MDMFAGMF_01570 2.9e-70 yqhY S Asp23 family, cell envelope-related function
MDMFAGMF_01571 1.2e-70 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MDMFAGMF_01572 3.6e-149 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MDMFAGMF_01573 1.1e-216 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDMFAGMF_01574 4.3e-43 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
MDMFAGMF_01575 1.1e-153 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
MDMFAGMF_01576 4.1e-150 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
MDMFAGMF_01577 3.3e-77 argR K Regulates arginine biosynthesis genes
MDMFAGMF_01578 1e-261 recN L May be involved in recombinational repair of damaged DNA
MDMFAGMF_01579 4.2e-53
MDMFAGMF_01580 4.2e-115 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
MDMFAGMF_01581 7.7e-32 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
MDMFAGMF_01582 6.4e-213 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MDMFAGMF_01583 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MDMFAGMF_01584 1.5e-175 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MDMFAGMF_01585 6.3e-249 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MDMFAGMF_01586 5.9e-132 stp 3.1.3.16 T phosphatase
MDMFAGMF_01587 0.0 KLT serine threonine protein kinase
MDMFAGMF_01588 4.5e-163 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
MDMFAGMF_01589 1.5e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
MDMFAGMF_01590 2.6e-120 thiN 2.7.6.2 H thiamine pyrophosphokinase
MDMFAGMF_01591 7e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
MDMFAGMF_01592 3e-57 asp S Asp23 family, cell envelope-related function
MDMFAGMF_01593 0.0 yloV S DAK2 domain fusion protein YloV
MDMFAGMF_01594 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MDMFAGMF_01595 1.2e-186 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
MDMFAGMF_01596 2.9e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
MDMFAGMF_01597 4.2e-132 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
MDMFAGMF_01598 0.0 smc D Required for chromosome condensation and partitioning
MDMFAGMF_01599 9.4e-185 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MDMFAGMF_01600 1.3e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MDMFAGMF_01601 3e-249 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MDMFAGMF_01602 2.2e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
MDMFAGMF_01603 4.1e-40 ylqC S Belongs to the UPF0109 family
MDMFAGMF_01604 6.9e-92 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MDMFAGMF_01605 9.9e-143 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
MDMFAGMF_01606 2.6e-261 yfnA E amino acid
MDMFAGMF_01607 3.6e-64 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
MDMFAGMF_01608 7.7e-35
MDMFAGMF_01609 1.6e-52 S Mazg nucleotide pyrophosphohydrolase
MDMFAGMF_01610 2.2e-159 xth 3.1.11.2 L exodeoxyribonuclease III
MDMFAGMF_01611 1.1e-83
MDMFAGMF_01612 3e-187 lacR K Transcriptional regulator
MDMFAGMF_01613 8e-36 lacS G Transporter
MDMFAGMF_01614 8.5e-251 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MDMFAGMF_01615 1e-68 UW LPXTG-motif cell wall anchor domain protein
MDMFAGMF_01635 1.1e-153 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
MDMFAGMF_01636 1.3e-198 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
MDMFAGMF_01637 1.2e-108 rfbC 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
MDMFAGMF_01638 2.3e-162 rfbA 2.7.7.24 H Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
MDMFAGMF_01639 1.1e-250 L PFAM transposase, IS4 family protein
MDMFAGMF_01640 1.1e-250 L PFAM transposase, IS4 family protein
MDMFAGMF_01642 2.2e-08 S Phage derived protein Gp49-like (DUF891)
MDMFAGMF_01643 8e-12 S Phage derived protein Gp49-like (DUF891)
MDMFAGMF_01644 8.5e-20 K Helix-turn-helix XRE-family like proteins
MDMFAGMF_01645 8.8e-164 I alpha/beta hydrolase fold
MDMFAGMF_01646 3.1e-113 frnE Q DSBA-like thioredoxin domain
MDMFAGMF_01647 8.1e-55
MDMFAGMF_01649 1e-34 carB 6.3.5.5 F Carbamoyl-phosphate synthase
MDMFAGMF_01650 9.2e-281 L Transposase IS66 family
MDMFAGMF_01651 3.1e-62 XK27_01125 L PFAM IS66 Orf2 family protein
MDMFAGMF_01653 1.9e-59 IQ Dehydrogenase reductase
MDMFAGMF_01654 8.3e-238 yhjE EGP MFS transporter, metabolite H symporter (MHS) family protein
MDMFAGMF_01656 2.1e-20 E Zn peptidase
MDMFAGMF_01657 4.8e-25 3.4.21.88 K Peptidase S24-like
MDMFAGMF_01658 6.5e-57
MDMFAGMF_01660 8.2e-138 mltD CBM50 M NlpC P60 family protein
MDMFAGMF_01661 5.7e-29
MDMFAGMF_01662 2.1e-182 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
MDMFAGMF_01663 9.8e-32 ykzG S Belongs to the UPF0356 family
MDMFAGMF_01664 8.8e-81
MDMFAGMF_01665 1.3e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
MDMFAGMF_01666 6.3e-207 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
MDMFAGMF_01667 8.1e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
MDMFAGMF_01668 3.5e-228 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
MDMFAGMF_01669 1.2e-274 lpdA 1.8.1.4 C Dehydrogenase
MDMFAGMF_01670 1.4e-47 yktA S Belongs to the UPF0223 family
MDMFAGMF_01671 6.3e-137 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
MDMFAGMF_01672 0.0 typA T GTP-binding protein TypA
MDMFAGMF_01673 2.9e-221 ftsW D Belongs to the SEDS family
MDMFAGMF_01674 3e-44 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
MDMFAGMF_01675 1.2e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
MDMFAGMF_01676 5.1e-90 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MDMFAGMF_01677 2.3e-198 ylbL T Belongs to the peptidase S16 family
MDMFAGMF_01678 1.4e-78 comEA L Competence protein ComEA
MDMFAGMF_01679 3.1e-89 comEB 3.5.4.12 F ComE operon protein 2
MDMFAGMF_01680 0.0 comEC S Competence protein ComEC
MDMFAGMF_01681 5.3e-147 holA 2.7.7.7 L DNA polymerase III delta subunit
MDMFAGMF_01682 6.1e-294 L Transposase
MDMFAGMF_01683 5.1e-35 rpsT J Binds directly to 16S ribosomal RNA
MDMFAGMF_01684 1.6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MDMFAGMF_01685 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
MDMFAGMF_01686 3.5e-163 S Tetratricopeptide repeat
MDMFAGMF_01687 3.8e-226 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MDMFAGMF_01688 2.8e-238 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
MDMFAGMF_01689 1.8e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MDMFAGMF_01690 3.6e-108 engB D Necessary for normal cell division and for the maintenance of normal septation
MDMFAGMF_01691 6.1e-60 MA20_27270 S mazG nucleotide pyrophosphohydrolase
MDMFAGMF_01692 7.6e-09
MDMFAGMF_01693 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
MDMFAGMF_01694 2.3e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MDMFAGMF_01695 2.4e-175 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
MDMFAGMF_01696 3.2e-155 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
MDMFAGMF_01697 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
MDMFAGMF_01698 9.2e-92 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MDMFAGMF_01699 2.5e-88
MDMFAGMF_01701 2.3e-127 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDMFAGMF_01702 1.1e-212 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
MDMFAGMF_01703 5.5e-115 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MDMFAGMF_01704 1.3e-35 ynzC S UPF0291 protein
MDMFAGMF_01705 9.8e-30 yneF S Uncharacterised protein family (UPF0154)
MDMFAGMF_01706 7.8e-117 plsC 2.3.1.51 I Acyltransferase
MDMFAGMF_01707 4.1e-141 yabB 2.1.1.223 L Methyltransferase small domain
MDMFAGMF_01708 5.4e-49 yazA L GIY-YIG catalytic domain protein
MDMFAGMF_01709 2e-183 ldhD 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MDMFAGMF_01710 1.2e-143 rpsB J Belongs to the universal ribosomal protein uS2 family
MDMFAGMF_01711 2.4e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MDMFAGMF_01712 1.7e-129 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
MDMFAGMF_01713 4.8e-94 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
MDMFAGMF_01714 3.5e-140 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MDMFAGMF_01715 8.4e-137 cdsA 2.7.7.41 I Belongs to the CDS family
MDMFAGMF_01716 3.7e-235 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
MDMFAGMF_01717 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
MDMFAGMF_01718 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MDMFAGMF_01719 2.5e-83 rimP J Required for maturation of 30S ribosomal subunits
MDMFAGMF_01720 2.8e-216 nusA K Participates in both transcription termination and antitermination
MDMFAGMF_01721 1e-44 ylxR K Protein of unknown function (DUF448)
MDMFAGMF_01722 1.7e-48 ylxQ J ribosomal protein
MDMFAGMF_01723 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MDMFAGMF_01724 2.1e-58 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MDMFAGMF_01725 1.8e-167 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MDMFAGMF_01726 1.5e-177 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
MDMFAGMF_01727 2e-64
MDMFAGMF_01728 9e-195 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
MDMFAGMF_01729 4.3e-74 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MDMFAGMF_01730 0.0 dnaK O Heat shock 70 kDa protein
MDMFAGMF_01731 7.3e-198 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
MDMFAGMF_01732 1.2e-71 S Metallo-beta-lactamase superfamily
MDMFAGMF_01733 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
MDMFAGMF_01734 1.7e-273 pipD E Dipeptidase
MDMFAGMF_01735 1.1e-200 mdh 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
MDMFAGMF_01737 2.3e-173 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
MDMFAGMF_01738 7.5e-58
MDMFAGMF_01739 7.5e-180 prmA J Ribosomal protein L11 methyltransferase
MDMFAGMF_01740 2.1e-129 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
MDMFAGMF_01741 1.2e-52
MDMFAGMF_01742 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MDMFAGMF_01743 4.2e-77 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
MDMFAGMF_01744 4.3e-230 L transposase, IS605 OrfB family
MDMFAGMF_01745 3.1e-66 L PFAM transposase IS200-family protein
MDMFAGMF_01746 6.5e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
MDMFAGMF_01747 2.7e-25
MDMFAGMF_01748 1.8e-124 G Peptidase_C39 like family
MDMFAGMF_01749 2.5e-164 glsA 3.5.1.2 E Belongs to the glutaminase family
MDMFAGMF_01759 1.5e-101 arsB 1.20.4.1 P Sodium Bile acid symporter family
MDMFAGMF_01760 2.9e-69 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MDMFAGMF_01761 4.6e-24 K Helix-turn-helix domain
MDMFAGMF_01762 6.7e-31 WQ51_00220 K Helix-turn-helix domain
MDMFAGMF_01763 6.7e-105 S Protein of unknown function (DUF3278)
MDMFAGMF_01764 1.2e-07
MDMFAGMF_01765 8.3e-182 ABC-SBP S ABC transporter
MDMFAGMF_01766 1.1e-153 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
MDMFAGMF_01767 4.8e-137 XK27_08845 S ABC transporter, ATP-binding protein
MDMFAGMF_01768 2.2e-94 P Cadmium resistance transporter
MDMFAGMF_01769 1.3e-54 K Transcriptional regulator, ArsR family
MDMFAGMF_01770 6.6e-235 mepA V MATE efflux family protein
MDMFAGMF_01771 9.4e-55 trxA O Belongs to the thioredoxin family
MDMFAGMF_01772 6.6e-131 terC P membrane
MDMFAGMF_01773 1.1e-167 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
MDMFAGMF_01774 1.5e-166 corA P CorA-like Mg2+ transporter protein
MDMFAGMF_01775 4e-275 pipD E Dipeptidase
MDMFAGMF_01776 1.6e-241 pbuX F xanthine permease
MDMFAGMF_01777 1.3e-249 nhaC C Na H antiporter NhaC
MDMFAGMF_01778 5.3e-284 S C4-dicarboxylate anaerobic carrier
MDMFAGMF_01779 5.5e-126 pgm3 3.1.3.73 G phosphoglycerate mutase family
MDMFAGMF_01780 3.8e-41
MDMFAGMF_01781 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
MDMFAGMF_01782 2.4e-206 gldA 1.1.1.6 C dehydrogenase
MDMFAGMF_01783 1.8e-124 S Alpha beta hydrolase
MDMFAGMF_01784 1.6e-216 dacA 3.4.16.4 M Belongs to the peptidase S11 family
MDMFAGMF_01785 2.7e-100
MDMFAGMF_01787 1.2e-123 yciB M ErfK YbiS YcfS YnhG
MDMFAGMF_01788 8.1e-260 S Putative peptidoglycan binding domain
MDMFAGMF_01789 9.3e-110 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
MDMFAGMF_01790 3.5e-88
MDMFAGMF_01791 3.4e-244 hisS 6.1.1.21 J histidyl-tRNA synthetase
MDMFAGMF_01792 1.2e-216 yttB EGP Major facilitator Superfamily
MDMFAGMF_01793 6.3e-103
MDMFAGMF_01794 1e-24
MDMFAGMF_01795 5.5e-175 scrR K Transcriptional regulator, LacI family
MDMFAGMF_01796 6.3e-238 acm2 3.2.1.17 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
MDMFAGMF_01797 1e-48 czrA K Transcriptional regulator, ArsR family
MDMFAGMF_01798 7.3e-36
MDMFAGMF_01799 0.0 yhcA V ABC transporter, ATP-binding protein
MDMFAGMF_01800 2.6e-118 devA 3.6.3.25 V ABC transporter, ATP-binding protein
MDMFAGMF_01801 2.2e-172 hrtB V ABC transporter permease
MDMFAGMF_01802 5.5e-89 ygfC K transcriptional regulator (TetR family)
MDMFAGMF_01803 9.9e-191 tdh 1.1.1.14 E Alcohol dehydrogenase GroES-like domain
MDMFAGMF_01804 1e-290 mntH P H( )-stimulated, divalent metal cation uptake system
MDMFAGMF_01805 7.8e-30
MDMFAGMF_01806 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MDMFAGMF_01808 4.3e-228 yxiO S Vacuole effluxer Atg22 like
MDMFAGMF_01809 1.2e-254 npp S type I phosphodiesterase nucleotide pyrophosphatase
MDMFAGMF_01810 2.9e-241 E amino acid
MDMFAGMF_01811 6.7e-181 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MDMFAGMF_01812 3.3e-211 yxjG_1 E methionine synthase, vitamin-B12 independent
MDMFAGMF_01813 1.6e-41 S Cytochrome B5
MDMFAGMF_01814 5.4e-09 S Cytochrome B5
MDMFAGMF_01815 1.8e-39 S Cytochrome B5
MDMFAGMF_01816 7.8e-76 elaA S Gnat family
MDMFAGMF_01817 1.4e-121 GM NmrA-like family
MDMFAGMF_01818 2.8e-51 hxlR K Transcriptional regulator, HxlR family
MDMFAGMF_01819 5.7e-109 XK27_02070 S Nitroreductase family
MDMFAGMF_01820 1.2e-82 K Transcriptional regulator, HxlR family
MDMFAGMF_01821 1.6e-228
MDMFAGMF_01822 3.8e-210 EGP Major facilitator Superfamily
MDMFAGMF_01823 1.4e-256 pepC 3.4.22.40 E aminopeptidase
MDMFAGMF_01824 9.9e-112 ylbE GM NAD dependent epimerase dehydratase family protein
MDMFAGMF_01825 0.0 pepN 3.4.11.2 E aminopeptidase
MDMFAGMF_01826 1.2e-92 folT S ECF transporter, substrate-specific component
MDMFAGMF_01827 1.1e-197 asnA 6.3.1.1 F aspartate--ammonia ligase
MDMFAGMF_01828 1.3e-256 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
MDMFAGMF_01829 1.4e-119 yhjH 3.1.4.52 T Putative diguanylate phosphodiesterase
MDMFAGMF_01830 6e-200 2.7.7.65 T GGDEF domain
MDMFAGMF_01831 2.1e-128 yfeJ 6.3.5.2 F glutamine amidotransferase
MDMFAGMF_01832 8.2e-63 yneR
MDMFAGMF_01833 2.5e-110 GM NAD(P)H-binding
MDMFAGMF_01834 1.1e-185 S membrane
MDMFAGMF_01835 6.9e-104 K Transcriptional regulator C-terminal region
MDMFAGMF_01836 1.9e-158 akr5f 1.1.1.346 S reductase
MDMFAGMF_01837 3.7e-133 K Transcriptional regulator
MDMFAGMF_01838 1.3e-84 L PFAM transposase IS200-family protein
MDMFAGMF_01841 1.5e-64 L PFAM Integrase catalytic region
MDMFAGMF_01842 1.8e-74 4.4.1.5 E Glyoxalase
MDMFAGMF_01843 7.2e-138 S Membrane
MDMFAGMF_01844 1.9e-138 S Belongs to the UPF0246 family
MDMFAGMF_01845 0.0 oxc 4.1.1.8 EH Belongs to the TPP enzyme family
MDMFAGMF_01846 1e-259 frc 2.8.3.16 C Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate
MDMFAGMF_01847 7.4e-234 pbuG S permease
MDMFAGMF_01848 3.7e-108 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MDMFAGMF_01849 8.4e-251 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MDMFAGMF_01850 1e-215 iscS2 2.8.1.7 E Aminotransferase class V
MDMFAGMF_01851 8.5e-229 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MDMFAGMF_01852 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
MDMFAGMF_01853 1.5e-272 cydA 1.10.3.14 C ubiquinol oxidase
MDMFAGMF_01854 5.3e-184 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
MDMFAGMF_01855 1.8e-309 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
MDMFAGMF_01856 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MDMFAGMF_01857 5.3e-231 ndh 1.6.99.3 C NADH dehydrogenase
MDMFAGMF_01858 2.2e-243 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
MDMFAGMF_01859 1.8e-121 radC L DNA repair protein
MDMFAGMF_01860 1.7e-179 mreB D cell shape determining protein MreB
MDMFAGMF_01861 5e-151 mreC M Involved in formation and maintenance of cell shape
MDMFAGMF_01862 8.7e-93 mreD M rod shape-determining protein MreD
MDMFAGMF_01863 3.2e-102 glnP P ABC transporter permease
MDMFAGMF_01864 7.2e-118 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
MDMFAGMF_01865 2.6e-160 aatB ET ABC transporter substrate-binding protein
MDMFAGMF_01866 1.7e-229 ymfF S Peptidase M16 inactive domain protein
MDMFAGMF_01867 3.5e-249 ymfH S Peptidase M16
MDMFAGMF_01868 1.1e-139 ymfM S Helix-turn-helix domain
MDMFAGMF_01869 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MDMFAGMF_01870 1.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
MDMFAGMF_01871 7.6e-197 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MDMFAGMF_01872 9.5e-209 rny S Endoribonuclease that initiates mRNA decay
MDMFAGMF_01873 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MDMFAGMF_01874 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MDMFAGMF_01875 8.7e-102 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
MDMFAGMF_01876 1e-190 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
MDMFAGMF_01877 2.1e-194 tgt_1 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
MDMFAGMF_01878 8.2e-31 yajC U Preprotein translocase
MDMFAGMF_01879 3.2e-183 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
MDMFAGMF_01880 3.7e-233 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
MDMFAGMF_01881 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MDMFAGMF_01882 4.5e-42 yrzL S Belongs to the UPF0297 family
MDMFAGMF_01883 3.6e-76 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MDMFAGMF_01884 6.1e-48 yrzB S Belongs to the UPF0473 family
MDMFAGMF_01885 1.6e-86 cvpA S Colicin V production protein
MDMFAGMF_01886 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
MDMFAGMF_01887 5.1e-53 trxA O Belongs to the thioredoxin family
MDMFAGMF_01888 1.6e-97 yslB S Protein of unknown function (DUF2507)
MDMFAGMF_01889 4.2e-144 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
MDMFAGMF_01890 3.1e-104 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MDMFAGMF_01891 2.9e-93 S Phosphoesterase
MDMFAGMF_01892 3.3e-74 ykuL S (CBS) domain
MDMFAGMF_01893 1.5e-152 3.1.3.102, 3.1.3.104, 3.1.3.23 S haloacid dehalogenase-like hydrolase
MDMFAGMF_01894 8.1e-149 ykuT M mechanosensitive ion channel
MDMFAGMF_01895 6.5e-38 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
MDMFAGMF_01896 4.9e-28
MDMFAGMF_01897 1.6e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
MDMFAGMF_01898 7.1e-181 ccpA K catabolite control protein A
MDMFAGMF_01899 4e-124
MDMFAGMF_01900 3.5e-132 yebC K Transcriptional regulatory protein
MDMFAGMF_01901 2.3e-184 comGA NU Type II IV secretion system protein
MDMFAGMF_01902 2.2e-185 comGB NU type II secretion system
MDMFAGMF_01903 7.1e-47 comGC U competence protein ComGC
MDMFAGMF_01904 1.1e-77 NU general secretion pathway protein
MDMFAGMF_01905 1.1e-41
MDMFAGMF_01906 1.8e-69
MDMFAGMF_01908 7.7e-146 ytxK 2.1.1.72 L N-6 DNA Methylase
MDMFAGMF_01909 2.2e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MDMFAGMF_01910 4.7e-111 S Calcineurin-like phosphoesterase
MDMFAGMF_01911 6.6e-93 yutD S Protein of unknown function (DUF1027)
MDMFAGMF_01912 2.7e-132 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
MDMFAGMF_01913 1.9e-102 S Protein of unknown function (DUF1461)
MDMFAGMF_01914 5.5e-110 dedA S SNARE-like domain protein
MDMFAGMF_01916 3.3e-90 bioY S BioY family
MDMFAGMF_01917 4e-173 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
MDMFAGMF_01918 5.3e-184 phoH T phosphate starvation-inducible protein PhoH
MDMFAGMF_01919 6e-69 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MDMFAGMF_01920 3.8e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
MDMFAGMF_01921 2.8e-168 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MDMFAGMF_01922 5.8e-146 recO L Involved in DNA repair and RecF pathway recombination
MDMFAGMF_01923 2e-180 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
MDMFAGMF_01924 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
MDMFAGMF_01925 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
MDMFAGMF_01926 1.7e-207 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
MDMFAGMF_01927 9.1e-220 patA 2.6.1.1 E Aminotransferase
MDMFAGMF_01928 1.7e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
MDMFAGMF_01929 2.3e-153 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MDMFAGMF_01930 3.9e-237 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
MDMFAGMF_01931 5.2e-30 S Protein of unknown function (DUF2929)
MDMFAGMF_01932 0.0 dnaE 2.7.7.7 L DNA polymerase
MDMFAGMF_01933 1.4e-270 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
MDMFAGMF_01934 4.6e-168 cvfB S S1 domain
MDMFAGMF_01935 1.7e-165 xerD D recombinase XerD
MDMFAGMF_01936 1.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
MDMFAGMF_01937 2.9e-137 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MDMFAGMF_01938 9.4e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MDMFAGMF_01939 5e-128 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
MDMFAGMF_01940 7.6e-103 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MDMFAGMF_01941 1.3e-193 ypbB 5.1.3.1 S Helix-turn-helix domain
MDMFAGMF_01942 4e-270 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
MDMFAGMF_01943 2.5e-13 M Lysin motif
MDMFAGMF_01944 7.6e-118 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
MDMFAGMF_01945 1.4e-205 rpsA 1.17.7.4 J Ribosomal protein S1
MDMFAGMF_01946 1.6e-249 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
MDMFAGMF_01947 2.6e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
MDMFAGMF_01948 1.3e-235 S Tetratricopeptide repeat protein
MDMFAGMF_01949 3e-226 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MDMFAGMF_01950 0.0 yfmR S ABC transporter, ATP-binding protein
MDMFAGMF_01951 2.2e-192 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MDMFAGMF_01952 5.1e-92 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MDMFAGMF_01953 5.3e-113 hlyIII S protein, hemolysin III
MDMFAGMF_01954 4.4e-152 DegV S EDD domain protein, DegV family
MDMFAGMF_01955 3.4e-169 ypmR E lipolytic protein G-D-S-L family
MDMFAGMF_01956 3.7e-108 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
MDMFAGMF_01957 4.4e-35 yozE S Belongs to the UPF0346 family
MDMFAGMF_01958 1.1e-161 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MDMFAGMF_01959 5e-142 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MDMFAGMF_01960 9e-164 dprA LU DNA protecting protein DprA
MDMFAGMF_01961 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MDMFAGMF_01962 4.9e-170 lacX 5.1.3.3 G Aldose 1-epimerase
MDMFAGMF_01963 7.9e-106 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
MDMFAGMF_01964 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDMFAGMF_01965 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
MDMFAGMF_01966 3.5e-82 F NUDIX domain
MDMFAGMF_01967 1.1e-172 ppaC 3.6.1.1 C inorganic pyrophosphatase
MDMFAGMF_01968 4.1e-68 yqkB S Belongs to the HesB IscA family
MDMFAGMF_01969 1.6e-49
MDMFAGMF_01971 1.7e-87 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
MDMFAGMF_01972 8.7e-63 asp S Asp23 family, cell envelope-related function
MDMFAGMF_01973 2.3e-24
MDMFAGMF_01974 4.2e-95
MDMFAGMF_01975 6.6e-287 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDMFAGMF_01976 1.2e-183 K Transcriptional regulator, LacI family
MDMFAGMF_01977 1.6e-233 gntT EG Gluconate
MDMFAGMF_01978 7.2e-294 gntK 2.7.1.12, 2.7.1.17 G Belongs to the FGGY kinase family
MDMFAGMF_01979 1.2e-94 K Acetyltransferase (GNAT) domain
MDMFAGMF_01980 4.2e-47
MDMFAGMF_01981 2.4e-22
MDMFAGMF_01982 0.0 nylA 3.5.1.4 J Belongs to the amidase family
MDMFAGMF_01983 1.1e-43
MDMFAGMF_01984 1.2e-56 yhaI S Protein of unknown function (DUF805)
MDMFAGMF_01985 8.8e-300 2.1.1.72 V type I restriction-modification system
MDMFAGMF_01986 5.6e-10 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)