ORF_ID e_value Gene_name EC_number CAZy COGs Description
HIMGIKDF_00001 6e-252 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HIMGIKDF_00002 6.1e-205 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HIMGIKDF_00003 2.4e-33 yaaA S S4 domain
HIMGIKDF_00004 1.4e-206 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HIMGIKDF_00005 1.8e-37 yaaB S Domain of unknown function (DUF370)
HIMGIKDF_00006 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMGIKDF_00007 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HIMGIKDF_00008 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00011 2.7e-182 yaaC S YaaC-like Protein
HIMGIKDF_00012 1.8e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
HIMGIKDF_00013 5.2e-248 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HIMGIKDF_00014 2.2e-157 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
HIMGIKDF_00015 8e-108 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
HIMGIKDF_00016 4.3e-207 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HIMGIKDF_00017 1.3e-09
HIMGIKDF_00018 2.2e-122 dck 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxycytidine kinase
HIMGIKDF_00019 3.2e-115 dgk 2.7.1.113, 2.7.1.74, 2.7.1.76 F Deoxyguanosine kinase
HIMGIKDF_00020 5.6e-215 yaaH M Glycoside Hydrolase Family
HIMGIKDF_00021 2.4e-98 yaaI Q COG1335 Amidases related to nicotinamidase
HIMGIKDF_00022 1e-84 tadA 3.5.4.1, 3.5.4.3, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HIMGIKDF_00023 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMGIKDF_00024 5.3e-37 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HIMGIKDF_00025 3.9e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HIMGIKDF_00026 7.9e-32 yaaL S Protein of unknown function (DUF2508)
HIMGIKDF_00027 3.7e-36 bofA S Sigma-K factor-processing regulatory protein BofA
HIMGIKDF_00028 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00031 3.4e-31 csfB S Inhibitor of sigma-G Gin
HIMGIKDF_00032 4.7e-103 xpaC S 5-bromo-4-chloroindolyl phosphate hydrolysis protein
HIMGIKDF_00033 4.5e-203 yaaN P Belongs to the TelA family
HIMGIKDF_00034 1.1e-275 adiA 4.1.1.17, 4.1.1.18, 4.1.1.19 E Orn Lys Arg decarboxylase
HIMGIKDF_00035 3.6e-114 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HIMGIKDF_00036 2.2e-54 yaaQ S protein conserved in bacteria
HIMGIKDF_00037 1.5e-71 yaaR S protein conserved in bacteria
HIMGIKDF_00038 2.2e-182 holB 2.7.7.7 L DNA polymerase III
HIMGIKDF_00039 2.1e-146 yaaT S stage 0 sporulation protein
HIMGIKDF_00040 4.8e-31 yabA L Involved in initiation control of chromosome replication
HIMGIKDF_00041 2.5e-138 yabB 2.1.1.223 S Conserved hypothetical protein 95
HIMGIKDF_00042 1.5e-49 yazA L endonuclease containing a URI domain
HIMGIKDF_00043 4.3e-158 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HIMGIKDF_00044 8.8e-44 abrB K COG2002 Regulators of stationary sporulation gene expression
HIMGIKDF_00045 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HIMGIKDF_00046 1.8e-144 tatD L hydrolase, TatD
HIMGIKDF_00047 4.3e-194 rpfB GH23 T protein conserved in bacteria
HIMGIKDF_00048 8.4e-99 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HIMGIKDF_00049 2.4e-156 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HIMGIKDF_00050 3.3e-137 yabG S peptidase
HIMGIKDF_00051 7.8e-39 veg S protein conserved in bacteria
HIMGIKDF_00052 8.3e-27 sspF S DNA topological change
HIMGIKDF_00053 4.1e-161 ispE 2.1.1.182, 2.7.1.148 I Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HIMGIKDF_00054 2.6e-152 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HIMGIKDF_00055 3.8e-63 yabJ 3.5.99.10 J translation initiation inhibitor, yjgF family
HIMGIKDF_00056 1e-47 spoVG D Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation
HIMGIKDF_00057 6.6e-230 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HIMGIKDF_00058 9.4e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HIMGIKDF_00059 3.9e-97 ctc J This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HIMGIKDF_00060 8e-105 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HIMGIKDF_00061 2.4e-39 yabK S Peptide ABC transporter permease
HIMGIKDF_00062 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HIMGIKDF_00063 1.5e-92 spoVT K stage V sporulation protein
HIMGIKDF_00064 2.4e-287 yabM S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_00065 2.7e-245 mazG 3.6.1.66, 3.6.1.9 S COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like
HIMGIKDF_00066 1.1e-37 yabO J COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
HIMGIKDF_00067 1.5e-49 yabP S Sporulation protein YabP
HIMGIKDF_00068 3.9e-108 yabQ S spore cortex biosynthesis protein
HIMGIKDF_00069 1.1e-44 divIC D Septum formation initiator
HIMGIKDF_00070 8.5e-58 yabR J RNA binding protein (contains ribosomal protein S1 domain)
HIMGIKDF_00073 0.0 spoIIE 3.1.3.16, 3.1.3.3 KT stage II sporulation protein E
HIMGIKDF_00074 1.5e-124 yabS S protein containing a von Willebrand factor type A (vWA) domain
HIMGIKDF_00075 6.7e-187 KLT serine threonine protein kinase
HIMGIKDF_00076 3.5e-274 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HIMGIKDF_00077 7.9e-94 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HIMGIKDF_00078 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HIMGIKDF_00079 1.5e-146 coaX 2.7.1.33 F Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HIMGIKDF_00080 2.9e-162 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HIMGIKDF_00081 3.1e-153 yacD 5.2.1.8 O peptidyl-prolyl isomerase
HIMGIKDF_00082 8.9e-170 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMGIKDF_00083 4.7e-271 pabB 2.6.1.85 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIMGIKDF_00084 1.5e-106 pabA 2.6.1.85, 4.1.3.27 EH Anthranilate synthase
HIMGIKDF_00085 1.6e-168 pabC 2.6.1.42, 4.1.3.38 EH 4-amino-4-deoxychorismate lyase
HIMGIKDF_00086 2.6e-160 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HIMGIKDF_00087 8.2e-63 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HIMGIKDF_00088 2.7e-88 folK 1.13.11.81, 2.5.1.15, 2.7.6.3, 3.5.4.16, 4.1.2.25, 5.1.99.8 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HIMGIKDF_00089 4.1e-30 yazB K transcriptional
HIMGIKDF_00090 3.7e-190 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMGIKDF_00091 1.3e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HIMGIKDF_00092 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00097 2e-08
HIMGIKDF_00102 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00103 2.9e-76 ctsR K Belongs to the CtsR family
HIMGIKDF_00104 4.7e-47 mcsA 2.7.14.1 S protein with conserved CXXC pairs
HIMGIKDF_00105 6.1e-202 mcsB 2.7.14.1, 2.7.3.2, 2.7.3.3 E Catalyzes the specific phosphorylation of arginine residues in a large number of proteins. Is part of the bacterial stress response system. Protein arginine phosphorylation has a physiologically important role and is involved in the regulation of many critical cellular processes, such as protein homeostasis, motility, competence, and stringent and stress responses, by regulating gene expression and protein activity
HIMGIKDF_00106 0.0 clpC O Belongs to the ClpA ClpB family
HIMGIKDF_00107 9.6e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HIMGIKDF_00108 1.3e-196 disA 2.7.7.85 L Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
HIMGIKDF_00109 2.7e-197 yacL S COG4956 Integral membrane protein (PIN domain superfamily)
HIMGIKDF_00110 3.8e-125 ispD 2.7.7.60, 4.6.1.12 I Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)
HIMGIKDF_00111 3.1e-86 ispF 2.1.1.228, 2.7.7.60, 4.6.1.12 I Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)
HIMGIKDF_00112 1.9e-280 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HIMGIKDF_00113 7.2e-118 cysE 2.3.1.30 E Serine acetyltransferase
HIMGIKDF_00114 4.9e-273 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMGIKDF_00115 1e-72 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HIMGIKDF_00116 1.2e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMGIKDF_00117 1.2e-88 yacP S RNA-binding protein containing a PIN domain
HIMGIKDF_00118 1.5e-115 sigH K Belongs to the sigma-70 factor family
HIMGIKDF_00119 1e-21 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HIMGIKDF_00120 4.9e-96 nusG K Participates in transcription elongation, termination and antitermination
HIMGIKDF_00121 2.8e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HIMGIKDF_00122 1.1e-124 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HIMGIKDF_00123 5.1e-79 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HIMGIKDF_00124 1.3e-42 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HIMGIKDF_00125 8.2e-108 rsmC 2.1.1.172 J Methyltransferase
HIMGIKDF_00126 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMGIKDF_00127 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMGIKDF_00128 8e-33 ybxF J Belongs to the eukaryotic ribosomal protein eL8 family
HIMGIKDF_00129 8.5e-72 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HIMGIKDF_00130 6e-82 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HIMGIKDF_00131 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HIMGIKDF_00132 2.5e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HIMGIKDF_00133 9.1e-186 ybaC 3.4.11.5 S Alpha/beta hydrolase family
HIMGIKDF_00134 7.5e-49 rpsJ J Involved in the binding of tRNA to the ribosomes
HIMGIKDF_00135 6.3e-111 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HIMGIKDF_00136 3e-105 rplD J Forms part of the polypeptide exit tunnel
HIMGIKDF_00137 1.2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HIMGIKDF_00138 1.5e-155 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HIMGIKDF_00139 3.7e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HIMGIKDF_00140 4.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HIMGIKDF_00141 6.2e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HIMGIKDF_00142 1.3e-75 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HIMGIKDF_00143 1.7e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HIMGIKDF_00144 3.5e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HIMGIKDF_00145 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HIMGIKDF_00146 6.2e-51 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HIMGIKDF_00147 4.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HIMGIKDF_00148 3.4e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMGIKDF_00149 3.9e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HIMGIKDF_00150 1.3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HIMGIKDF_00151 4e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HIMGIKDF_00152 3.1e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HIMGIKDF_00153 1.9e-23 rpmD J Ribosomal protein L30
HIMGIKDF_00154 1.8e-72 rplO J binds to the 23S rRNA
HIMGIKDF_00155 4.2e-234 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HIMGIKDF_00156 5.7e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HIMGIKDF_00157 3.7e-142 map 3.4.11.18 E Methionine aminopeptidase
HIMGIKDF_00158 1.1e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HIMGIKDF_00159 4.2e-13 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
HIMGIKDF_00160 3.1e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HIMGIKDF_00161 2.1e-64 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HIMGIKDF_00162 3.1e-170 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HIMGIKDF_00163 3.6e-58 rplQ J Ribosomal protein L17
HIMGIKDF_00164 5.1e-156 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMGIKDF_00165 1.7e-154 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMGIKDF_00166 4.7e-119 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HIMGIKDF_00167 2.8e-142 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HIMGIKDF_00168 6.4e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HIMGIKDF_00169 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HIMGIKDF_00170 8.2e-145 ybaJ Q Methyltransferase domain
HIMGIKDF_00171 9.7e-66 ybaK S Protein of unknown function (DUF2521)
HIMGIKDF_00172 1.1e-132 cwlD 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMGIKDF_00173 1.4e-198 mrp D Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP
HIMGIKDF_00174 1.2e-84 gerD
HIMGIKDF_00175 1.3e-102 kbaA 2.7.8.43 S Involved in the activation of the KinB signaling pathway of sporulation
HIMGIKDF_00176 1.2e-140 pdaB 3.5.1.104 G Polysaccharide deacetylase
HIMGIKDF_00177 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00180 2e-08
HIMGIKDF_00184 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00185 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00186 4.6e-250 ybaR P COG0659 Sulfate permease and related transporters (MFS superfamily)
HIMGIKDF_00188 1.2e-161 ybaS 1.1.1.58 S Na -dependent transporter
HIMGIKDF_00189 2.2e-142 ybbA S Putative esterase
HIMGIKDF_00190 3e-179 feuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00191 1.1e-176 feuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00192 7.2e-167 feuA P Iron-uptake system-binding protein
HIMGIKDF_00193 5.4e-308 ybbB K COG2207 AraC-type DNA-binding domain-containing proteins
HIMGIKDF_00194 4.4e-241 ybbC 3.2.1.52 S protein conserved in bacteria
HIMGIKDF_00195 0.0 ybbD 3.2.1.52 G Belongs to the glycosyl hydrolase 3 family
HIMGIKDF_00196 4e-256 yfeW 3.4.16.4 V Belongs to the UPF0214 family
HIMGIKDF_00197 9.8e-234 ybbF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_00198 1.1e-150 ybbH K transcriptional
HIMGIKDF_00199 2.1e-163 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HIMGIKDF_00200 6.4e-87 ybbJ J acetyltransferase
HIMGIKDF_00201 3.9e-78 ybbK 2.4.2.1, 6.3.2.4 S Protein of unknown function (DUF523)
HIMGIKDF_00207 8.5e-99 sigW K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_00208 1.7e-103 rsiW K Is the anti-sigma factor for SigW. The presence of RsiW leads to the inactivation of SigW, and its proteolytic destruction to sigma-W activation
HIMGIKDF_00209 2.7e-146 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMGIKDF_00210 3e-225 ybbR S protein conserved in bacteria
HIMGIKDF_00211 9.3e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HIMGIKDF_00212 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HIMGIKDF_00213 2.1e-176 alkA 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIMGIKDF_00214 1.4e-121 adaA 3.2.2.21 K Transcriptional regulator
HIMGIKDF_00215 5.1e-101 ogt 2.1.1.63, 3.2.2.21 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMGIKDF_00216 1.5e-278 ndhF 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HIMGIKDF_00217 0.0 ybcC S Belongs to the UPF0753 family
HIMGIKDF_00218 3.7e-96 can 4.2.1.1 P carbonic anhydrase
HIMGIKDF_00219 3.9e-47
HIMGIKDF_00220 4.7e-61 ybcI S Uncharacterized conserved protein (DUF2294)
HIMGIKDF_00221 5.1e-50 ybzH K Helix-turn-helix domain
HIMGIKDF_00222 2e-203 ybcL EGP Major facilitator Superfamily
HIMGIKDF_00224 9.1e-239 J 4Fe-4S single cluster domain
HIMGIKDF_00225 1.6e-277 V CAAX protease self-immunity
HIMGIKDF_00226 1.9e-135 skfE V ABC transporter
HIMGIKDF_00227 4e-248 skfF S ABC transporter
HIMGIKDF_00228 7.8e-91 C HEAT repeats
HIMGIKDF_00229 9.6e-79 txn CO Thioredoxin-like
HIMGIKDF_00230 6.2e-182 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIMGIKDF_00231 1.5e-123 T Transcriptional regulatory protein, C terminal
HIMGIKDF_00232 1.8e-173 T His Kinase A (phospho-acceptor) domain
HIMGIKDF_00234 1.6e-140 KLT Protein tyrosine kinase
HIMGIKDF_00235 4.8e-154 ybdN
HIMGIKDF_00236 1.5e-217 ybdO S Domain of unknown function (DUF4885)
HIMGIKDF_00237 2.4e-259 yifK E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_00238 3.7e-38 csgA S Sigma-G-dependent sporulation-specific SASP protein
HIMGIKDF_00239 4.9e-30 ybxH S Family of unknown function (DUF5370)
HIMGIKDF_00240 7.2e-152 ybxI 3.5.2.6 V beta-lactamase
HIMGIKDF_00241 1.4e-247 cypC 1.11.2.4, 1.14.14.1 Q Cytochrome P450
HIMGIKDF_00242 4.9e-41 ybyB
HIMGIKDF_00243 1.8e-290 ybeC E amino acid
HIMGIKDF_00244 5.6e-166 glpQ 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMGIKDF_00245 7.3e-258 glpT G -transporter
HIMGIKDF_00246 2.9e-35 S Protein of unknown function (DUF2651)
HIMGIKDF_00247 1.6e-171 ybfA 3.4.15.5 K FR47-like protein
HIMGIKDF_00248 2.2e-224 ybfB G COG0477 Permeases of the major facilitator superfamily
HIMGIKDF_00250 0.0 ybfG 3.2.1.132 M Domain of unknown function (DUF1906)
HIMGIKDF_00251 8.8e-162 ybfH EG EamA-like transporter family
HIMGIKDF_00252 2.3e-145 msmR K AraC-like ligand binding domain
HIMGIKDF_00253 1.9e-214 purT 2.1.2.2 F Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HIMGIKDF_00254 6.9e-178 mpr 3.4.21.19 M Belongs to the peptidase S1B family
HIMGIKDF_00256 2.5e-169 S Alpha/beta hydrolase family
HIMGIKDF_00257 3.2e-95 pssA 2.7.8.8 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMGIKDF_00258 2.7e-85 ybfM S SNARE associated Golgi protein
HIMGIKDF_00259 5.6e-149 psd 4.1.1.65 I Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer)
HIMGIKDF_00260 3.2e-46 ybfN
HIMGIKDF_00261 4.3e-258 S Erythromycin esterase
HIMGIKDF_00262 6.7e-167 ybfP K Transcriptional regulator
HIMGIKDF_00263 3.9e-192 yceA S Belongs to the UPF0176 family
HIMGIKDF_00264 4.9e-216 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMGIKDF_00265 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_00266 2.1e-137 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIMGIKDF_00267 4.9e-128 K UTRA
HIMGIKDF_00269 5.4e-203 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMGIKDF_00270 6.7e-262 mmuP E amino acid
HIMGIKDF_00271 9.3e-183 mmuM 1.5.1.20, 2.1.1.10 H homocysteine
HIMGIKDF_00272 2.3e-257 agcS E Sodium alanine symporter
HIMGIKDF_00273 1.5e-188 glsA 3.5.1.2 E Belongs to the glutaminase family
HIMGIKDF_00274 1.5e-229 phoQ 2.7.13.3 T Histidine kinase
HIMGIKDF_00275 9e-170 glnL T Regulator
HIMGIKDF_00276 2.7e-174 kdgD 4.2.1.41 EM 5-dehydro-4-deoxyglucarate dehydratase activity
HIMGIKDF_00277 3.7e-274 ycbD C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMGIKDF_00278 1.2e-255 gudP G COG0477 Permeases of the major facilitator superfamily
HIMGIKDF_00279 2.2e-270 gudD 4.2.1.40 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HIMGIKDF_00280 1.5e-124 ycbG K FCD
HIMGIKDF_00281 3.7e-298 garD 4.2.1.42, 4.2.1.7 G Altronate
HIMGIKDF_00282 1.8e-178 ycbJ S Macrolide 2'-phosphotransferase
HIMGIKDF_00283 4.4e-24 rtpA K Tryptophan RNA-binding attenuator protein inhibitory protein
HIMGIKDF_00284 7.3e-172 eamA1 EG spore germination
HIMGIKDF_00285 1.7e-125 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_00286 2.4e-170 T PhoQ Sensor
HIMGIKDF_00287 4.8e-168 ycbN V ABC transporter, ATP-binding protein
HIMGIKDF_00288 2.1e-115 S ABC-2 family transporter protein
HIMGIKDF_00289 8.2e-53 ycbP S Protein of unknown function (DUF2512)
HIMGIKDF_00290 1.3e-78 sleB 3.5.1.28 M Cell wall
HIMGIKDF_00291 6.6e-136 ycbR T vWA found in TerF C terminus
HIMGIKDF_00292 0.0 phoD 3.1.3.1 P COG3540 Phosphodiesterase alkaline phosphatase D
HIMGIKDF_00293 5e-28 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIMGIKDF_00294 1.2e-124 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIMGIKDF_00295 1.4e-121 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HIMGIKDF_00296 6.2e-210 ycbU E Selenocysteine lyase
HIMGIKDF_00297 5.8e-229 lmrB EGP the major facilitator superfamily
HIMGIKDF_00298 4.8e-102 yxaF K Transcriptional regulator
HIMGIKDF_00299 2.2e-202 ansB 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
HIMGIKDF_00300 5.6e-115 lip 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HIMGIKDF_00301 2e-59 S RDD family
HIMGIKDF_00302 9.5e-200 yccF K DNA-templated transcriptional preinitiation complex assembly
HIMGIKDF_00303 2e-161 2.7.13.3 T GHKL domain
HIMGIKDF_00304 1.2e-126 lytR_2 T LytTr DNA-binding domain
HIMGIKDF_00305 4.1e-133 natA 3.6.3.7 CP ATPases associated with a variety of cellular activities
HIMGIKDF_00306 4.5e-203 natB CP ABC-2 family transporter protein
HIMGIKDF_00307 1.6e-174 yccK C Aldo keto reductase
HIMGIKDF_00308 6.6e-177 ycdA S Domain of unknown function (DUF5105)
HIMGIKDF_00309 5.9e-282 ycdB K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_00310 6.7e-268 ycdC K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_00311 1.7e-95 cwlK M D-alanyl-D-alanine carboxypeptidase
HIMGIKDF_00312 5.5e-174 S response regulator aspartate phosphatase
HIMGIKDF_00313 1.6e-140 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_00314 0.0 ycdG 3.2.1.10 GH13 G COG0366 Glycosidases
HIMGIKDF_00315 6.6e-168 adcA P Belongs to the bacterial solute-binding protein 9 family
HIMGIKDF_00316 2.5e-132 adcC P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HIMGIKDF_00317 1.7e-135 adcB P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HIMGIKDF_00318 5.4e-189 yceB C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_00319 3.9e-110 yceC 3.5.4.33 T proteins involved in stress response, homologs of TerZ and
HIMGIKDF_00320 2.8e-105 yceD T proteins involved in stress response, homologs of TerZ and
HIMGIKDF_00321 4.6e-108 yceE T proteins involved in stress response, homologs of TerZ and
HIMGIKDF_00322 6.3e-137 terC P Protein of unknown function (DUF475)
HIMGIKDF_00323 0.0 yceG S Putative component of 'biosynthetic module'
HIMGIKDF_00324 2e-192 yceH P Belongs to the TelA family
HIMGIKDF_00325 1e-218 naiP P Uncharacterised MFS-type transporter YbfB
HIMGIKDF_00326 1.9e-209 yceJ EGP Uncharacterised MFS-type transporter YbfB
HIMGIKDF_00327 1.6e-45 K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMGIKDF_00328 5.1e-229 proV 3.6.3.32 E glycine betaine
HIMGIKDF_00329 1.3e-127 opuAB P glycine betaine
HIMGIKDF_00330 5.3e-164 opuAC E glycine betaine
HIMGIKDF_00331 1.2e-219 amhX S amidohydrolase
HIMGIKDF_00332 1e-257 ycgA S Membrane
HIMGIKDF_00333 1.1e-98 ycgB
HIMGIKDF_00334 0.0 amyE 3.2.1.1 GH13 G alpha-amylase
HIMGIKDF_00335 3.3e-183 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HIMGIKDF_00336 6.5e-293 lctP C L-lactate permease
HIMGIKDF_00337 6.2e-269 mdr EGP Major facilitator Superfamily
HIMGIKDF_00338 3.4e-77 emrR K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_00339 6.8e-113 ycgF E Lysine exporter protein LysE YggA
HIMGIKDF_00340 1.2e-151 yqcI S YqcI/YcgG family
HIMGIKDF_00341 5.6e-250 ycgH E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_00342 2.4e-112 ycgI S Domain of unknown function (DUF1989)
HIMGIKDF_00343 1.5e-149 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HIMGIKDF_00344 2.5e-109 tmrB S AAA domain
HIMGIKDF_00345 3e-104 aroK 2.7.1.71, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HIMGIKDF_00346 3.6e-145 yafE Q ubiE/COQ5 methyltransferase family
HIMGIKDF_00347 1.1e-178 oxyR3 K LysR substrate binding domain
HIMGIKDF_00348 2.9e-184 cah 3.1.1.41 Q Acetyl xylan esterase (AXE1)
HIMGIKDF_00349 2.9e-145 ycgL S Predicted nucleotidyltransferase
HIMGIKDF_00350 5.1e-170 ycgM E Proline dehydrogenase
HIMGIKDF_00351 7.3e-294 rocA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIMGIKDF_00352 9e-248 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMGIKDF_00353 1.6e-227 ycgP QT COG2508 Regulator of polyketide synthase expression
HIMGIKDF_00354 2.6e-147 ycgQ S membrane
HIMGIKDF_00355 1.2e-139 ycgR S permeases
HIMGIKDF_00356 5.7e-163 I alpha/beta hydrolase fold
HIMGIKDF_00357 1.3e-193 ycgT 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HIMGIKDF_00358 9.3e-283 cobA 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HIMGIKDF_00359 4.6e-57 nirD 1.7.1.15 P Nitrite reductase
HIMGIKDF_00360 0.0 nirB 1.7.1.15 C Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HIMGIKDF_00361 0.0 nasC C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMGIKDF_00362 0.0 nirB 1.7.1.15 C Assimilatory nitrate reductase (electron transfer subunit)
HIMGIKDF_00363 7.6e-222 nasA P COG2223 Nitrate nitrite transporter
HIMGIKDF_00364 1.4e-172 folE2 3.5.4.16 S Converts GTP to 7,8-dihydroneopterin triphosphate
HIMGIKDF_00365 5.5e-109 yciB M ErfK YbiS YcfS YnhG
HIMGIKDF_00366 1.4e-228 yciC S GTPases (G3E family)
HIMGIKDF_00367 2.4e-116 yecS P COG0765 ABC-type amino acid transport system, permease component
HIMGIKDF_00368 1.1e-132 yckB ET COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain
HIMGIKDF_00370 3.3e-77 yckC S membrane
HIMGIKDF_00371 3.5e-52 yckD S Protein of unknown function (DUF2680)
HIMGIKDF_00372 1.2e-298 yckE 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMGIKDF_00373 3.4e-70 nin S Competence protein J (ComJ)
HIMGIKDF_00374 3.2e-72 nucA M Deoxyribonuclease NucA/NucB
HIMGIKDF_00375 3e-187 tlpC 2.7.13.3 NT chemotaxis protein
HIMGIKDF_00376 4.6e-97 hxlB 4.1.2.43, 5.3.1.27 G SIS domain
HIMGIKDF_00377 3.3e-107 hxlA 4.1.2.43 G 3-hexulose-6-phosphate synthase
HIMGIKDF_00378 1.3e-63 hxlR K transcriptional
HIMGIKDF_00379 0.0 srfAA Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_00380 0.0 srfAB Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_00381 0.0 srfAC Q COG1020 Non-ribosomal peptide synthetase modules and related proteins
HIMGIKDF_00382 5.7e-140 srfAD Q thioesterase
HIMGIKDF_00383 4.2e-228 EGP Major Facilitator Superfamily
HIMGIKDF_00384 4.9e-91 S YcxB-like protein
HIMGIKDF_00385 7.4e-164 ycxC EG EamA-like transporter family
HIMGIKDF_00386 4.4e-255 ycxD K GntR family transcriptional regulator
HIMGIKDF_00387 4.4e-75 acpT 2.7.8.7 H Belongs to the P-Pant transferase superfamily
HIMGIKDF_00388 4.4e-115 yczE S membrane
HIMGIKDF_00389 2.8e-134 tcyC 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMGIKDF_00390 6.2e-123 tcyB P COG0765 ABC-type amino acid transport system, permease component
HIMGIKDF_00391 1.5e-141 tcyA ET Belongs to the bacterial solute-binding protein 3 family
HIMGIKDF_00392 4.9e-162 bsdA K LysR substrate binding domain
HIMGIKDF_00393 2e-109 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HIMGIKDF_00394 1.8e-283 yclC 4.1.1.61 H Decarboxylase involved in the decarboxylation and detoxification of phenolic derivatives under both aerobic and anaerobic conditions. It is able to catalyze the reversible decarboxylation of 4-hydroxybenzoate
HIMGIKDF_00395 4e-39 bsdD 4.1.1.61 S response to toxic substance
HIMGIKDF_00396 1.1e-83 yclD
HIMGIKDF_00397 6.2e-162 yclE 3.4.11.5 S Alpha beta hydrolase
HIMGIKDF_00398 1.5e-267 dtpT E amino acid peptide transporter
HIMGIKDF_00399 2.9e-310 yclG M Pectate lyase superfamily protein
HIMGIKDF_00401 6.8e-282 gerKA EG Spore germination protein
HIMGIKDF_00402 1.3e-232 gerKC S spore germination
HIMGIKDF_00403 9.9e-200 gerKB F Spore germination protein
HIMGIKDF_00404 3.9e-122 yclH P ABC transporter
HIMGIKDF_00405 1.7e-204 yclI V ABC transporter (permease) YclI
HIMGIKDF_00406 1.4e-127 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_00407 1.8e-262 yclK 2.7.13.3 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HIMGIKDF_00408 5.2e-71 S aspartate phosphatase
HIMGIKDF_00411 1.5e-253 lysC 2.7.2.4 E Belongs to the aspartokinase family
HIMGIKDF_00412 1.6e-161 yclN P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00413 2.6e-164 fatC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00414 4.7e-137 yclP 3.6.3.34 P ABC transporter, ATP-binding protein
HIMGIKDF_00415 5.5e-175 yclQ P COG4607 ABC-type enterochelin transport system, periplasmic component
HIMGIKDF_00416 1.4e-251 ycnB EGP Major facilitator Superfamily
HIMGIKDF_00417 6.5e-154 ycnC K Transcriptional regulator
HIMGIKDF_00418 4.4e-135 nfrA2 1.5.1.38, 1.5.1.39 C Oxidoreductase
HIMGIKDF_00419 1.6e-45 ycnE S Monooxygenase
HIMGIKDF_00420 2.2e-51 yczG K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMGIKDF_00421 1.3e-273 gabR K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_00422 4.4e-247 gabT 2.6.1.19, 2.6.1.22 E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMGIKDF_00423 3.4e-266 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMGIKDF_00424 6.1e-149 glcU U Glucose uptake
HIMGIKDF_00425 9.9e-146 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_00426 1.3e-100 ycnI S protein conserved in bacteria
HIMGIKDF_00427 1.4e-308 ycnJ P protein, homolog of Cu resistance protein CopC
HIMGIKDF_00428 1.7e-107 ycnK K COG1349 Transcriptional regulators of sugar metabolism
HIMGIKDF_00429 7.3e-56
HIMGIKDF_00430 5.6e-240 mtlA 2.7.1.197 G COG2213 Phosphotransferase system, mannitol-specific IIBC component
HIMGIKDF_00431 2e-71 mtlF 2.7.1.197 G COG4668 Mannitol fructose-specific phosphotransferase system, IIA domain
HIMGIKDF_00432 7.3e-211 mtlD 1.1.1.17 G COG0246 Mannitol-1-phosphate altronate dehydrogenases
HIMGIKDF_00433 3.8e-201 ycsA 1.1.1.83, 1.1.1.93, 4.1.1.73 CE Tartrate dehydrogenase
HIMGIKDF_00434 3.2e-10 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMGIKDF_00435 7.6e-76 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMGIKDF_00436 5e-113 M1-673 3.1.1.45 Q COG0412 Dienelactone hydrolase and related enzymes
HIMGIKDF_00437 5.4e-68 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HIMGIKDF_00439 8e-137 ycsE 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HIMGIKDF_00440 1.2e-140 ycsF S Belongs to the UPF0271 (lamB) family
HIMGIKDF_00441 6.5e-213 ycsG P COG1914 Mn2 and Fe2 transporters of the NRAMP family
HIMGIKDF_00442 9.6e-149 ycsI S Belongs to the D-glutamate cyclase family
HIMGIKDF_00443 1.9e-135 kipI 3.5.1.54 E Allophanate hydrolase subunit 1
HIMGIKDF_00444 5.1e-187 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HIMGIKDF_00445 1.2e-132 kipR K Transcriptional regulator
HIMGIKDF_00446 9.9e-120 ycsK E anatomical structure formation involved in morphogenesis
HIMGIKDF_00448 1.4e-49 yczJ S biosynthesis
HIMGIKDF_00449 0.0 pbpC 3.4.16.4 M Penicillin-binding Protein
HIMGIKDF_00450 2.8e-176 ydhF S Oxidoreductase
HIMGIKDF_00451 0.0 mtlR K transcriptional regulator, MtlR
HIMGIKDF_00452 1.4e-294 ydaB IQ acyl-CoA ligase
HIMGIKDF_00453 1.1e-99 ydaC Q Methyltransferase domain
HIMGIKDF_00454 1.4e-161 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_00455 1.2e-96 MA20_27600 5.3.1.15 S Cupin 2, conserved barrel domain protein
HIMGIKDF_00456 5e-104 rimL 1.1.1.25 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIMGIKDF_00457 6.8e-77 ydaG 1.4.3.5 S general stress protein
HIMGIKDF_00458 4.1e-139 amj U Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
HIMGIKDF_00459 5.1e-47 ydzA EGP Major facilitator Superfamily
HIMGIKDF_00460 2.5e-74 lrpC K Transcriptional regulator
HIMGIKDF_00461 0.0 topB 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMGIKDF_00462 1.9e-208 ydaJ M Belongs to the glycosyl hydrolase 8 (cellulase D) family
HIMGIKDF_00463 2e-152 ydaK T Diguanylate cyclase, GGDEF domain
HIMGIKDF_00464 0.0 ydaL S Uncharacterized protein conserved in bacteria (DUF2334)
HIMGIKDF_00465 4.5e-233 ydaM M Glycosyl transferase family group 2
HIMGIKDF_00466 0.0 ydaN S Bacterial cellulose synthase subunit
HIMGIKDF_00467 0.0 ydaO E amino acid
HIMGIKDF_00468 4.6e-79 mutT 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
HIMGIKDF_00469 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HIMGIKDF_00470 9.4e-40
HIMGIKDF_00471 1e-224 mntH P H( )-stimulated, divalent metal cation uptake system
HIMGIKDF_00473 3.3e-77 ydaT S Uncharacterized protein conserved in bacteria (DUF2188)
HIMGIKDF_00474 3.8e-148 ydbA 3.6.3.4, 3.6.3.54 P EcsC protein family
HIMGIKDF_00476 8.9e-59 ydbB G Cupin domain
HIMGIKDF_00477 2.8e-63 ydbC S Domain of unknown function (DUF4937
HIMGIKDF_00478 3.2e-155 ydbD P Catalase
HIMGIKDF_00479 2.7e-199 dctB G COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component
HIMGIKDF_00480 2.5e-297 dctS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMGIKDF_00481 8.1e-120 dctR T COG4565 Response regulator of citrate malate metabolism
HIMGIKDF_00482 6.3e-227 dctA U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMGIKDF_00483 4.4e-181 ydbI S AI-2E family transporter
HIMGIKDF_00484 3.6e-171 ydbJ V ABC transporter, ATP-binding protein
HIMGIKDF_00485 5.5e-125 ydbK S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIMGIKDF_00486 2.7e-52 ydbL
HIMGIKDF_00487 3e-220 ydbM 1.3.8.1 I acyl-CoA dehydrogenase
HIMGIKDF_00488 1.1e-18 S Fur-regulated basic protein B
HIMGIKDF_00489 2.2e-07 S Fur-regulated basic protein A
HIMGIKDF_00490 1.9e-150 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMGIKDF_00491 2.3e-56 ydbP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIMGIKDF_00492 4.6e-202 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HIMGIKDF_00493 1.9e-259 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HIMGIKDF_00494 9e-249 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HIMGIKDF_00495 2.1e-82 ydbS S Bacterial PH domain
HIMGIKDF_00496 2.2e-263 ydbT S Membrane
HIMGIKDF_00497 1.8e-107 ydcA 3.4.21.105 S membrane protein (homolog of Drosophila rhomboid)
HIMGIKDF_00498 2.5e-59 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HIMGIKDF_00499 2.9e-183 ydcC M COG2834 Outer membrane lipoprotein-sorting protein
HIMGIKDF_00500 2.3e-223 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMGIKDF_00501 4.8e-42 ndoAI K transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain
HIMGIKDF_00502 2.5e-56 ndoA L Toxic component of a toxin-antitoxin (TA) module
HIMGIKDF_00503 1.3e-143 rsbR T Positive regulator of sigma-B
HIMGIKDF_00504 5.2e-57 rsbS T antagonist
HIMGIKDF_00505 1.3e-69 rsbT 2.7.11.1 T COG2172 Anti-sigma regulatory factor (Ser Thr protein kinase)
HIMGIKDF_00506 7.1e-189 rsbU 3.1.3.3 KT phosphatase
HIMGIKDF_00507 7e-53 rsbV T Belongs to the anti-sigma-factor antagonist family
HIMGIKDF_00508 2.4e-86 rsbW 2.7.11.1 F Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)
HIMGIKDF_00509 3.4e-138 sigB K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_00510 4.8e-108 rsbX 3.1.3.16, 3.1.3.3 KT Sigma factor PP2C-like phosphatases
HIMGIKDF_00514 1.5e-82 ydcG S EVE domain
HIMGIKDF_00515 1.6e-76 ydcH K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_00516 0.0 yhgF K COG2183 Transcriptional accessory protein
HIMGIKDF_00517 1.6e-84 ydcK S Belongs to the SprT family
HIMGIKDF_00525 2.7e-188 luxA C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_00526 2.4e-71 lrpA K transcriptional
HIMGIKDF_00527 3.9e-78 lrpB K transcriptional
HIMGIKDF_00528 9.6e-100 yddQ 3.5.1.19 Q Isochorismatase family
HIMGIKDF_00529 1.5e-143 yddR S Zn-dependent hydrolases of the beta-lactamase fold
HIMGIKDF_00530 5e-227 ydeG EGP Major facilitator Superfamily
HIMGIKDF_00535 1.4e-112 ydeA 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HIMGIKDF_00536 8.7e-30 cspL K Cold shock
HIMGIKDF_00537 6.1e-79 carD K Transcription factor
HIMGIKDF_00538 4.6e-35 ydzE EG spore germination
HIMGIKDF_00539 1.1e-166 rhaS5 K AraC-like ligand binding domain
HIMGIKDF_00540 2.3e-173 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
HIMGIKDF_00541 2.5e-166 ydeE K AraC family transcriptional regulator
HIMGIKDF_00542 2.2e-265 K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_00543 3.4e-220 ydeG EGP Major facilitator superfamily
HIMGIKDF_00544 2.9e-47 ydeH
HIMGIKDF_00545 8.9e-107 ydeI S Bacteriocin-protection, YdeI or OmpD-Associated
HIMGIKDF_00546 4e-116
HIMGIKDF_00547 1.8e-153 ydeK EG -transporter
HIMGIKDF_00548 1.5e-274 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_00549 4.2e-74 maoC I N-terminal half of MaoC dehydratase
HIMGIKDF_00550 8.6e-107 ydeN S Serine hydrolase
HIMGIKDF_00551 1.1e-58 K HxlR-like helix-turn-helix
HIMGIKDF_00552 1.9e-153 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HIMGIKDF_00553 4.8e-69 ydeP K Transcriptional regulator
HIMGIKDF_00554 1.6e-108 ydeQ S NADPH-quinone reductase (modulator of drug activity B)
HIMGIKDF_00555 1.2e-195 ydeR EGP Major facilitator Superfamily
HIMGIKDF_00556 8.4e-105 ydeS K Transcriptional regulator
HIMGIKDF_00557 1.3e-57 arsR K transcriptional
HIMGIKDF_00558 5.2e-232 arsB P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIMGIKDF_00559 7.2e-149 ydfB J GNAT acetyltransferase
HIMGIKDF_00560 1e-162 ydfC EG EamA-like transporter family
HIMGIKDF_00561 1.9e-275 ydfD K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_00562 5.9e-117 ydfE S Flavin reductase like domain
HIMGIKDF_00563 2.7e-123 ydfF K helix_turn_helix, Arsenical Resistance Operon Repressor
HIMGIKDF_00564 1.5e-79 ydfG S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIMGIKDF_00566 5.3e-180 ydfH 2.7.13.3 T Histidine kinase
HIMGIKDF_00567 1.4e-110 ydfI K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_00568 0.0 ydfJ S drug exporters of the RND superfamily
HIMGIKDF_00569 1.9e-177 S Alpha/beta hydrolase family
HIMGIKDF_00570 5.9e-118 S Protein of unknown function (DUF554)
HIMGIKDF_00571 3.2e-147 K Bacterial transcription activator, effector binding domain
HIMGIKDF_00572 1.6e-155 fieF P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMGIKDF_00573 9.6e-112 ydfN C nitroreductase
HIMGIKDF_00574 3.6e-187 ydfO E COG0346 Lactoylglutathione lyase and related lyases
HIMGIKDF_00575 8.8e-63 mhqP S DoxX
HIMGIKDF_00576 1.3e-57 traF CO Thioredoxin
HIMGIKDF_00577 7.1e-15 ydgA S Spore germination protein gerPA/gerPF
HIMGIKDF_00578 6.3e-29
HIMGIKDF_00580 4.4e-118 ydfR S Protein of unknown function (DUF421)
HIMGIKDF_00581 5.2e-122 ydfS S Protein of unknown function (DUF421)
HIMGIKDF_00582 1.7e-75 cotP O Belongs to the small heat shock protein (HSP20) family
HIMGIKDF_00583 1.4e-37 ydgA S Spore germination protein gerPA/gerPF
HIMGIKDF_00584 1.3e-41 ydgB S Spore germination protein gerPA/gerPF
HIMGIKDF_00585 1.5e-101 K Bacterial regulatory proteins, tetR family
HIMGIKDF_00586 1.9e-53 S DoxX-like family
HIMGIKDF_00587 2.4e-86 yycN 2.3.1.128 K Acetyltransferase
HIMGIKDF_00588 4.2e-308 expZ S ABC transporter
HIMGIKDF_00589 4e-251 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_00590 4.6e-91 dinB S DinB family
HIMGIKDF_00591 4.7e-80 K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_00592 0.0 ydgH S drug exporters of the RND superfamily
HIMGIKDF_00593 1e-113 drgA C nitroreductase
HIMGIKDF_00594 1.1e-69 ydgJ K Winged helix DNA-binding domain
HIMGIKDF_00595 2.5e-209 tcaB EGP Major facilitator Superfamily
HIMGIKDF_00596 1.2e-121 ydhB S membrane transporter protein
HIMGIKDF_00597 6.5e-122 ydhC K FCD
HIMGIKDF_00598 3.3e-244 ydhD M Glycosyl hydrolase
HIMGIKDF_00599 7e-228 ydhE CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIMGIKDF_00600 1.9e-127
HIMGIKDF_00601 1.4e-259 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HIMGIKDF_00602 4.6e-69 frataxin S Domain of unknown function (DU1801)
HIMGIKDF_00604 4.1e-86 K Acetyltransferase (GNAT) domain
HIMGIKDF_00605 1.8e-184 ydhJ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HIMGIKDF_00606 1.7e-99 ydhK M Protein of unknown function (DUF1541)
HIMGIKDF_00607 4.6e-200 pbuE EGP Major facilitator Superfamily
HIMGIKDF_00608 1.1e-47 ydhM 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMGIKDF_00609 3.5e-52 ydhN3 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMGIKDF_00610 2e-239 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMGIKDF_00611 2.4e-288 ydhP 3.2.1.21, 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMGIKDF_00612 3.9e-133 ydhQ K UTRA
HIMGIKDF_00613 9.2e-172 gmuE 2.7.1.2, 2.7.1.4 GK COG1940 Transcriptional regulator sugar kinase
HIMGIKDF_00614 4.2e-191 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMGIKDF_00615 7.3e-216 gmuG 3.2.1.78 GH26 G Belongs to the glycosyl hydrolase 26 family
HIMGIKDF_00616 8.7e-78 ydhU P Catalase
HIMGIKDF_00617 1.1e-16 ydhU P Manganese containing catalase
HIMGIKDF_00620 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00621 7.8e-08
HIMGIKDF_00623 4.6e-185 thiL 2.7.4.16 H Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HIMGIKDF_00624 9.1e-86 ydiB 2.7.1.221, 5.1.1.1 S ATPase or kinase
HIMGIKDF_00625 9e-127 yeaZ 2.3.1.234 O COG1214 Inactive homolog of metal-dependent proteases
HIMGIKDF_00626 1.3e-84 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
HIMGIKDF_00627 3.6e-188 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HIMGIKDF_00628 0.0 ydiF S ABC transporter
HIMGIKDF_00629 5.5e-89 moaC 4.6.1.17 H Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)
HIMGIKDF_00630 8.8e-116 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HIMGIKDF_00631 7.5e-22 tatA U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
HIMGIKDF_00632 8.4e-126 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HIMGIKDF_00633 2.9e-27 ydiK S Domain of unknown function (DUF4305)
HIMGIKDF_00634 7.9e-129 ydiL S CAAX protease self-immunity
HIMGIKDF_00635 1.3e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HIMGIKDF_00636 1.2e-281 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HIMGIKDF_00638 6.4e-66 KL Phage plasmid primase P4 family
HIMGIKDF_00639 1.1e-250 2.1.1.37 L DNA (cytosine-5-)-methyltransferase activity
HIMGIKDF_00640 1.6e-232 ydiP 2.1.1.37 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
HIMGIKDF_00642 1.2e-199 V AAA domain (dynein-related subfamily)
HIMGIKDF_00643 4.9e-257 J LlaJI restriction endonuclease
HIMGIKDF_00644 1.1e-08 ydjC S Abhydrolase domain containing 18
HIMGIKDF_00645 0.0 K NB-ARC domain
HIMGIKDF_00646 3.8e-201 gutB 1.1.1.14 E Dehydrogenase
HIMGIKDF_00647 7.1e-256 gutA G MFS/sugar transport protein
HIMGIKDF_00648 1.5e-175 ydjE 2.7.1.4 G pfkB family carbohydrate kinase
HIMGIKDF_00649 5.1e-114 pspA KT Phage shock protein A
HIMGIKDF_00650 3.4e-178 ydjG 3.6.4.12 L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMGIKDF_00651 1.6e-137 ydjH S COG1512 Beta-propeller domains of methanol dehydrogenase type
HIMGIKDF_00652 1.4e-149 ydjI S virion core protein (lumpy skin disease virus)
HIMGIKDF_00653 4.7e-196 S Ion transport 2 domain protein
HIMGIKDF_00654 2.7e-258 iolT EGP Major facilitator Superfamily
HIMGIKDF_00655 5.2e-195 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
HIMGIKDF_00656 4.5e-64 ydjM M Lytic transglycolase
HIMGIKDF_00657 4.4e-157 ydjN U Involved in the tonB-independent uptake of proteins
HIMGIKDF_00659 1.4e-34 ydjO S Cold-inducible protein YdjO
HIMGIKDF_00660 9.5e-160 ydjP I Alpha/beta hydrolase family
HIMGIKDF_00661 2.4e-181 yeaA S Protein of unknown function (DUF4003)
HIMGIKDF_00662 0.0 cotA 1.10.3.4, 1.16.3.3 Q multicopper oxidases
HIMGIKDF_00663 2.6e-253 gabP E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_00664 7.6e-155 yeaB P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HIMGIKDF_00665 1.6e-177 yeaC S COG0714 MoxR-like ATPases
HIMGIKDF_00666 9.5e-225 yeaD S conserved protein (some members contain a von Willebrand factor type A (vWA) domain)
HIMGIKDF_00667 0.0 yebA E COG1305 Transglutaminase-like enzymes
HIMGIKDF_00668 3.7e-306 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HIMGIKDF_00669 6e-212 pbuG S permease
HIMGIKDF_00670 1.1e-118 yebC M Membrane
HIMGIKDF_00672 4e-93 yebE S UPF0316 protein
HIMGIKDF_00673 8e-28 yebG S NETI protein
HIMGIKDF_00674 2.5e-83 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HIMGIKDF_00675 7e-217 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HIMGIKDF_00676 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HIMGIKDF_00677 1.2e-132 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
HIMGIKDF_00678 2.9e-38 purS 6.3.2.6, 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMGIKDF_00679 5.1e-130 purQ 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMGIKDF_00680 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HIMGIKDF_00681 1.2e-271 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HIMGIKDF_00682 7.6e-178 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
HIMGIKDF_00683 1.3e-105 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HIMGIKDF_00684 1.2e-288 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
HIMGIKDF_00685 1.7e-235 purD 6.3.4.13 F Belongs to the GARS family
HIMGIKDF_00686 3.5e-73 K helix_turn_helix ASNC type
HIMGIKDF_00687 2.3e-232 yjeH E Amino acid permease
HIMGIKDF_00688 2.7e-27 S Protein of unknown function (DUF2892)
HIMGIKDF_00689 0.0 yerA 3.5.4.2 F adenine deaminase
HIMGIKDF_00690 3e-192 yerB S Protein of unknown function (DUF3048) C-terminal domain
HIMGIKDF_00691 4.8e-51 yerC S protein conserved in bacteria
HIMGIKDF_00692 3.2e-305 yerD 1.4.7.1 E Belongs to the glutamate synthase family
HIMGIKDF_00694 2.2e-125 pcrB I 35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
HIMGIKDF_00695 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HIMGIKDF_00696 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HIMGIKDF_00697 4.1e-220 camS S COG4851 Protein involved in sex pheromone biosynthesis
HIMGIKDF_00698 1.1e-197 yerI S homoserine kinase type II (protein kinase fold)
HIMGIKDF_00699 1.6e-123 sapB S MgtC SapB transporter
HIMGIKDF_00700 2e-264 putP E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMGIKDF_00701 2.1e-45 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMGIKDF_00702 1.2e-274 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HIMGIKDF_00703 3.1e-270 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HIMGIKDF_00704 4e-156 yerO K Transcriptional regulator
HIMGIKDF_00705 0.0 swrC V Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HIMGIKDF_00706 3e-170 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIMGIKDF_00707 1.2e-255 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMGIKDF_00708 3.2e-98 L Recombinase
HIMGIKDF_00709 3.2e-53 L Resolvase, N terminal domain
HIMGIKDF_00710 0.0 yeeA V Type II restriction enzyme, methylase subunits
HIMGIKDF_00711 0.0 yeeB L DEAD-like helicases superfamily
HIMGIKDF_00712 1.8e-212 pstS P T5orf172
HIMGIKDF_00714 6.2e-31 S Colicin immunity protein / pyocin immunity protein
HIMGIKDF_00715 5.5e-83 S Protein of unknown function, DUF600
HIMGIKDF_00716 0.0 L nucleic acid phosphodiester bond hydrolysis
HIMGIKDF_00717 1.8e-192 3.4.24.40 CO amine dehydrogenase activity
HIMGIKDF_00718 5.5e-214 S Tetratricopeptide repeat
HIMGIKDF_00720 9.4e-127 yeeN K transcriptional regulatory protein
HIMGIKDF_00722 1.2e-103 dhaR3 K Transcriptional regulator
HIMGIKDF_00723 9.7e-82 yesE S SnoaL-like domain
HIMGIKDF_00724 2.2e-159 yesF GM NAD(P)H-binding
HIMGIKDF_00725 5.3e-45 cotJA S Spore coat associated protein JA (CotJA)
HIMGIKDF_00726 1.5e-45 cotJB S CotJB protein
HIMGIKDF_00727 5.2e-104 cotJC P Spore Coat
HIMGIKDF_00728 4.2e-103 yesJ K Acetyltransferase (GNAT) family
HIMGIKDF_00730 4.4e-104 yesL S Protein of unknown function, DUF624
HIMGIKDF_00731 0.0 yesM 2.7.13.3 T Histidine kinase
HIMGIKDF_00732 2.9e-204 yesN K helix_turn_helix, arabinose operon control protein
HIMGIKDF_00733 5e-248 yesO G Bacterial extracellular solute-binding protein
HIMGIKDF_00734 2.8e-171 yesP G Binding-protein-dependent transport system inner membrane component
HIMGIKDF_00735 1.3e-165 yesQ P Binding-protein-dependent transport system inner membrane component
HIMGIKDF_00736 1.6e-199 3.2.1.172 GH105 S Glycosyl Hydrolase Family 88
HIMGIKDF_00737 0.0 yesS K Transcriptional regulator
HIMGIKDF_00738 3.8e-133 E GDSL-like Lipase/Acylhydrolase
HIMGIKDF_00739 8.9e-132 yesU S Domain of unknown function (DUF1961)
HIMGIKDF_00740 1e-113 yesV S Protein of unknown function, DUF624
HIMGIKDF_00741 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HIMGIKDF_00742 0.0 yesX 4.2.2.23, 4.2.2.24 PL11 E cell wall organization
HIMGIKDF_00743 1.7e-108 yesY E GDSL-like Lipase/Acylhydrolase
HIMGIKDF_00744 0.0 yesZ 3.2.1.23 G beta-galactosidase activity
HIMGIKDF_00745 0.0 yetA
HIMGIKDF_00746 9.6e-291 lplA G Bacterial extracellular solute-binding protein
HIMGIKDF_00747 1.3e-176 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HIMGIKDF_00748 1.7e-162 lplC G Binding-protein-dependent transport system inner membrane component
HIMGIKDF_00749 3.3e-258 lplD 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HIMGIKDF_00750 6.1e-123 yetF S membrane
HIMGIKDF_00751 4.4e-55 isdI 1.14.99.48, 1.14.99.57 S Antibiotic biosynthesis monooxygenase
HIMGIKDF_00752 2e-64 yetH E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_00753 2.2e-34
HIMGIKDF_00754 2.2e-89 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMGIKDF_00755 4.4e-43 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMGIKDF_00756 8.9e-20 yezD S Uncharacterized small protein (DUF2292)
HIMGIKDF_00757 5.3e-105 yetJ S Belongs to the BI1 family
HIMGIKDF_00758 5.4e-159 yetK EG EamA-like transporter family
HIMGIKDF_00759 6.4e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_00760 7.8e-213 yetM CH FAD binding domain
HIMGIKDF_00761 3.6e-199 yetN S Protein of unknown function (DUF3900)
HIMGIKDF_00762 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HIMGIKDF_00763 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMGIKDF_00764 2.1e-148 rfbF 2.7.7.33 JM Nucleotidyl transferase
HIMGIKDF_00765 1.9e-172 yfnG 4.2.1.45 M dehydratase
HIMGIKDF_00766 3.8e-181 yfnF M Nucleotide-diphospho-sugar transferase
HIMGIKDF_00767 1.4e-225 yfnE 2.4.1.338 GT2 S Glycosyltransferase like family 2
HIMGIKDF_00768 3.5e-190 yfnD M Nucleotide-diphospho-sugar transferase
HIMGIKDF_00769 2e-206 fsr P COG0477 Permeases of the major facilitator superfamily
HIMGIKDF_00770 7.8e-134 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HIMGIKDF_00771 1.3e-241 yfnA E amino acid
HIMGIKDF_00772 2.8e-279 yfmT 1.2.1.3, 1.2.1.67 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMGIKDF_00773 1.1e-113 yfmS NT chemotaxis protein
HIMGIKDF_00774 0.0 yfmR S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMGIKDF_00775 3e-75 yfmQ S Uncharacterised protein from bacillus cereus group
HIMGIKDF_00776 2.8e-70 yfmP K transcriptional
HIMGIKDF_00777 1.5e-209 yfmO EGP Major facilitator Superfamily
HIMGIKDF_00778 1.9e-297 yfmM S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMGIKDF_00779 6.3e-202 yfmL 3.6.4.13 L COG0513 Superfamily II DNA and RNA helicases
HIMGIKDF_00780 7.5e-82 yfmK 2.3.1.128 K acetyltransferase
HIMGIKDF_00781 8.5e-190 yfmJ S N-terminal domain of oxidoreductase
HIMGIKDF_00782 7.7e-214 G Major Facilitator Superfamily
HIMGIKDF_00783 3.3e-296 1.14.99.50 S Sulfatase-modifying factor enzyme 1
HIMGIKDF_00784 1.1e-149 yfmF 3.6.3.34 P ATPases associated with a variety of cellular activities
HIMGIKDF_00785 1.2e-169 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00786 4.3e-170 viuD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00787 3.4e-169 fecB P COG4594 ABC-type Fe3 -citrate transport system, periplasmic component
HIMGIKDF_00788 2.9e-24 S Protein of unknown function (DUF3212)
HIMGIKDF_00789 7.6e-58 yflT S Heat induced stress protein YflT
HIMGIKDF_00790 3.8e-240 pel 4.2.2.10, 4.2.2.2 G Pectate lyase
HIMGIKDF_00791 3.2e-235 yflS P Sodium:sulfate symporter transmembrane region
HIMGIKDF_00792 1e-290 citS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMGIKDF_00793 8.9e-119 citT T response regulator
HIMGIKDF_00794 3e-181 yflP S Tripartite tricarboxylate transporter family receptor
HIMGIKDF_00796 8.5e-227 citM C Citrate transporter
HIMGIKDF_00797 5.5e-152 yflN S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMGIKDF_00798 1.3e-217 nos 1.14.14.47 C Belongs to the NOS family. Bacterial NOS oxygenase subfamily
HIMGIKDF_00799 2.9e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HIMGIKDF_00800 9e-124 yflK S protein conserved in bacteria
HIMGIKDF_00801 4e-18 yflJ S Protein of unknown function (DUF2639)
HIMGIKDF_00802 4.1e-19 yflI
HIMGIKDF_00803 2.4e-50 yflH S Protein of unknown function (DUF3243)
HIMGIKDF_00804 1.1e-138 map 3.4.11.18 E Methionine aminopeptidase
HIMGIKDF_00805 1.1e-250 nagE 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G COG1263 Phosphotransferase system IIC components, glucose maltose N-acetylglucosamine-specific
HIMGIKDF_00806 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMGIKDF_00807 6e-67 yhdN S Domain of unknown function (DUF1992)
HIMGIKDF_00808 3.2e-256 agcS_1 E Sodium alanine symporter
HIMGIKDF_00809 1.6e-194 E Spore germination protein
HIMGIKDF_00811 5.1e-207 yfkR S spore germination
HIMGIKDF_00812 1.5e-283 yfkQ EG Spore germination protein
HIMGIKDF_00813 8.5e-257 treP 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_00814 0.0 treC 3.2.1.93 GH13 G COG0366 Glycosidases
HIMGIKDF_00815 1.8e-133 treR K transcriptional
HIMGIKDF_00816 1.6e-125 yfkO C nitroreductase
HIMGIKDF_00817 0.0 cpdB 3.1.3.5, 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HIMGIKDF_00818 1.6e-91 yfkM 1.11.1.6, 3.5.1.124 S protease
HIMGIKDF_00819 6.8e-207 ydiM EGP Major facilitator Superfamily
HIMGIKDF_00820 2.1e-29 yfkK S Belongs to the UPF0435 family
HIMGIKDF_00821 2.2e-84 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMGIKDF_00822 8.4e-51 yfkI S gas vesicle protein
HIMGIKDF_00823 9.7e-144 yihY S Belongs to the UPF0761 family
HIMGIKDF_00824 5e-08
HIMGIKDF_00825 6.9e-220 ycaD EGP COG0477 Permeases of the major facilitator superfamily
HIMGIKDF_00826 6.1e-183 cax P COG0387 Ca2 H antiporter
HIMGIKDF_00827 1.2e-146 yfkD S YfkD-like protein
HIMGIKDF_00828 6e-149 yfkC M Mechanosensitive ion channel
HIMGIKDF_00829 5.4e-222 yfkA S YfkB-like domain
HIMGIKDF_00830 1.1e-26 yfjT
HIMGIKDF_00831 2.6e-154 pdaA G deacetylase
HIMGIKDF_00832 4.2e-150 yfjR 1.1.1.31 I NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase
HIMGIKDF_00833 1.7e-184 corA P Mediates influx of magnesium ions
HIMGIKDF_00834 1e-167 yfjP 3.2.2.21 L COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
HIMGIKDF_00835 1.1e-267 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HIMGIKDF_00836 1.6e-39 S YfzA-like protein
HIMGIKDF_00837 5.1e-192 yfjN J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HIMGIKDF_00838 3.9e-86 yfjM S Psort location Cytoplasmic, score
HIMGIKDF_00839 3e-29 yfjL
HIMGIKDF_00840 1.2e-191 acoA C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMGIKDF_00841 1e-190 acoB C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMGIKDF_00842 2.9e-197 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMGIKDF_00843 6.4e-257 acoL 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMGIKDF_00844 0.0 acoR KQ COG3284 Transcriptional activator of acetoin glycerol metabolism
HIMGIKDF_00845 1.2e-25 sspH S Belongs to the SspH family
HIMGIKDF_00846 4e-56 yfjF S UPF0060 membrane protein
HIMGIKDF_00847 1.3e-80 S Family of unknown function (DUF5381)
HIMGIKDF_00848 1.8e-101 yfjD S Family of unknown function (DUF5381)
HIMGIKDF_00849 4.1e-144 yfjC
HIMGIKDF_00850 9.2e-191 yfjB
HIMGIKDF_00851 1.1e-44 yfjA S Belongs to the WXG100 family
HIMGIKDF_00852 9.9e-263 aglB 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIMGIKDF_00853 3.2e-141 glvR K Helix-turn-helix domain, rpiR family
HIMGIKDF_00854 4.7e-296 glvC 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_00855 2.1e-310 yfiB3 V ABC transporter
HIMGIKDF_00856 0.0 yfiC V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMGIKDF_00857 9.8e-65 mhqP S DoxX
HIMGIKDF_00858 5.7e-163 yfiE 1.13.11.2 S glyoxalase
HIMGIKDF_00859 1.5e-177 K AraC-like ligand binding domain
HIMGIKDF_00860 1.8e-262 iolT EGP Major facilitator Superfamily
HIMGIKDF_00861 8.4e-184 G Xylose isomerase
HIMGIKDF_00862 1.1e-233 S Oxidoreductase
HIMGIKDF_00864 1.1e-214 yxjM T Histidine kinase
HIMGIKDF_00865 3.2e-113 KT LuxR family transcriptional regulator
HIMGIKDF_00866 6.2e-171 V ABC transporter, ATP-binding protein
HIMGIKDF_00867 9.8e-214 V ABC-2 family transporter protein
HIMGIKDF_00868 4.6e-208 V COG0842 ABC-type multidrug transport system, permease component
HIMGIKDF_00869 8.3e-99 padR K transcriptional
HIMGIKDF_00870 4.4e-80 estA 3.1.1.3 S acetyltransferases and hydrolases with the alpha beta hydrolase fold
HIMGIKDF_00871 9e-198 yfiQ G COG3936 Protein involved in polysaccharide intercellular adhesin (PIA) synthesis biofilm formation
HIMGIKDF_00872 2e-109 yfiR K Transcriptional regulator
HIMGIKDF_00873 5.1e-221 yfiS EGP Major facilitator Superfamily
HIMGIKDF_00874 3.3e-100 yfiT S Belongs to the metal hydrolase YfiT family
HIMGIKDF_00875 8.7e-287 yfiU EGP Major facilitator Superfamily
HIMGIKDF_00876 3.1e-81 yfiV K transcriptional
HIMGIKDF_00877 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HIMGIKDF_00878 6.2e-182 yfiY P ABC transporter substrate-binding protein
HIMGIKDF_00879 3.1e-176 yfiZ P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00880 5.2e-171 yfhA P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_00881 1.8e-167 yfhB 5.3.3.17 S PhzF family
HIMGIKDF_00882 3.9e-107 yfhC C nitroreductase
HIMGIKDF_00883 2.1e-25 yfhD S YfhD-like protein
HIMGIKDF_00885 4.9e-173 yfhF S nucleoside-diphosphate sugar epimerase
HIMGIKDF_00886 1.1e-141 recX 2.4.1.337 GT4 S Modulates RecA activity
HIMGIKDF_00887 9.7e-52 yfhH S Protein of unknown function (DUF1811)
HIMGIKDF_00889 1.1e-209 yfhI EGP Major facilitator Superfamily
HIMGIKDF_00890 6.2e-20 sspK S reproduction
HIMGIKDF_00891 1.3e-44 yfhJ S WVELL protein
HIMGIKDF_00892 9.2e-92 batE T Bacterial SH3 domain homologues
HIMGIKDF_00893 3.5e-51 yfhL S SdpI/YhfL protein family
HIMGIKDF_00894 6.7e-172 yfhM S Alpha beta hydrolase
HIMGIKDF_00895 2.7e-185 csbB GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMGIKDF_00896 0.0 yfhO S Bacterial membrane protein YfhO
HIMGIKDF_00897 5.5e-186 yfhP S membrane-bound metal-dependent
HIMGIKDF_00898 7.8e-212 mutY L A G-specific
HIMGIKDF_00899 6.9e-36 yfhS
HIMGIKDF_00900 2.9e-134 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_00901 2.4e-08 sspE S Small, acid-soluble spore protein, gamma-type
HIMGIKDF_00902 1.5e-37 ygaB S YgaB-like protein
HIMGIKDF_00903 1.3e-104 ygaC J Belongs to the UPF0374 family
HIMGIKDF_00904 1.8e-301 ygaD V ABC transporter
HIMGIKDF_00905 8.7e-180 ygaE S Membrane
HIMGIKDF_00906 1.2e-246 gsaB 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HIMGIKDF_00907 2.8e-87 bcp 1.11.1.15 O Peroxiredoxin
HIMGIKDF_00908 4e-80 perR P Belongs to the Fur family
HIMGIKDF_00909 1.5e-56 ygzB S UPF0295 protein
HIMGIKDF_00910 6.7e-167 ygxA S Nucleotidyltransferase-like
HIMGIKDF_00911 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_00912 1.7e-51 S COG NOG14600 non supervised orthologous group
HIMGIKDF_00925 2e-08
HIMGIKDF_00929 2.7e-143 spo0M S COG4326 Sporulation control protein
HIMGIKDF_00930 3e-27
HIMGIKDF_00931 5.9e-134 pepE 3.4.11.2, 3.4.13.21 E Belongs to the peptidase S51 family
HIMGIKDF_00932 0.0 thiC 4.1.99.17 H Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HIMGIKDF_00933 1.9e-266 ygaK C Berberine and berberine like
HIMGIKDF_00935 3.2e-291 katA 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMGIKDF_00936 1.1e-145 ssuB P COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component
HIMGIKDF_00937 1.7e-171 ssuA M Sulfonate ABC transporter
HIMGIKDF_00938 1.5e-147 ssuC P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HIMGIKDF_00939 3.1e-217 ssuD 1.14.14.5 C Catalyzes the desulfonation of aliphatic sulfonates
HIMGIKDF_00941 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HIMGIKDF_00942 4.1e-78 ygaO
HIMGIKDF_00943 4.4e-29 K Transcriptional regulator
HIMGIKDF_00945 7.9e-114 yhzB S B3/4 domain
HIMGIKDF_00946 2.1e-224 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HIMGIKDF_00947 4.4e-177 yhbB S Putative amidase domain
HIMGIKDF_00948 8.2e-87 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HIMGIKDF_00949 1.2e-109 yhbD K Protein of unknown function (DUF4004)
HIMGIKDF_00950 1.6e-65 yhbE M COG1664 Integral membrane protein CcmA involved in cell shape determination
HIMGIKDF_00951 8.2e-75 yhbF M COG1664 Integral membrane protein CcmA involved in cell shape determination
HIMGIKDF_00952 0.0 prkA T Ser protein kinase
HIMGIKDF_00953 2.5e-225 yhbH S Belongs to the UPF0229 family
HIMGIKDF_00954 2.2e-76 yhbI K DNA-binding transcription factor activity
HIMGIKDF_00955 3.1e-97 yhbJ V COG1566 Multidrug resistance efflux pump
HIMGIKDF_00956 3.1e-271 yhcA EGP Major facilitator Superfamily
HIMGIKDF_00957 1e-98 yhcB 1.6.5.2 S Belongs to the WrbA family
HIMGIKDF_00958 2.8e-37 yhcC
HIMGIKDF_00959 7.8e-55
HIMGIKDF_00960 6.6e-60 yhcF K Transcriptional regulator
HIMGIKDF_00961 1.6e-123 yhcG V ABC transporter, ATP-binding protein
HIMGIKDF_00962 2.6e-166 yhcH V ABC transporter, ATP-binding protein
HIMGIKDF_00963 3.9e-165 yhcI S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIMGIKDF_00964 1e-30 cspB K Cold-shock protein
HIMGIKDF_00965 5.2e-153 metQ M Belongs to the nlpA lipoprotein family
HIMGIKDF_00966 1.2e-197 yhcK 2.7.7.65 T COG2199 FOG GGDEF domain
HIMGIKDF_00967 6.3e-220 ydjN U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMGIKDF_00968 3.7e-44 yhcM
HIMGIKDF_00969 2.1e-68 yhcN S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMGIKDF_00970 2.5e-167 yhcP
HIMGIKDF_00971 5.2e-100 yhcQ M Spore coat protein
HIMGIKDF_00972 0.0 yhcR 3.1.3.5, 3.1.31.1 F Belongs to the 5'-nucleotidase family
HIMGIKDF_00973 7.6e-106 yhcS 3.4.22.70 M COG3764 Sortase (surface protein transpeptidase)
HIMGIKDF_00974 7.9e-171 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMGIKDF_00975 9.3e-68 yhcU S Family of unknown function (DUF5365)
HIMGIKDF_00976 9.9e-68 yhcV S COG0517 FOG CBS domain
HIMGIKDF_00977 4.6e-120 yhcW 5.4.2.6 S hydrolase
HIMGIKDF_00978 2.7e-304 yhcX 3.5.1.3 K Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIMGIKDF_00979 1.1e-261 yhxA E Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMGIKDF_00980 5.2e-104 glpP K Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
HIMGIKDF_00981 1.9e-152 glpF G Belongs to the MIP aquaporin (TC 1.A.8) family
HIMGIKDF_00982 4.6e-293 glpK 2.7.1.30 C Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HIMGIKDF_00983 0.0 glpD 1.1.5.3 C Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
HIMGIKDF_00984 0.0 pmmB 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
HIMGIKDF_00985 5.5e-214 yhcY 2.7.13.3 T Histidine kinase
HIMGIKDF_00986 1.1e-113 yhcZ K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_00987 1.4e-84 azr 1.7.1.6 S NADPH-dependent FMN reductase
HIMGIKDF_00988 1.2e-38 yhdB S YhdB-like protein
HIMGIKDF_00989 4.8e-54 yhdC S Protein of unknown function (DUF3889)
HIMGIKDF_00990 7.9e-189 cwlS 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMGIKDF_00991 3.5e-76 nsrR K Transcriptional regulator
HIMGIKDF_00992 8.7e-239 ygxB M Conserved TM helix
HIMGIKDF_00993 2.1e-276 ycgB S Stage V sporulation protein R
HIMGIKDF_00994 5.8e-258 phoB 3.1.3.1 P Belongs to the alkaline phosphatase family
HIMGIKDF_00995 2.5e-141 lytE 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMGIKDF_00996 3.8e-162 citR K Transcriptional regulator
HIMGIKDF_00997 1.4e-206 citA 2.3.3.1 C Belongs to the citrate synthase family
HIMGIKDF_00998 4.9e-162 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_00999 3.4e-250 yhdG E amino acid
HIMGIKDF_01000 1.5e-242 yhdH S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIMGIKDF_01001 3.7e-276 ydeL K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_01002 6.9e-77 BH1582 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_01003 8.1e-45 yhdK S Sigma-M inhibitor protein
HIMGIKDF_01004 6.6e-201 yhdL S Sigma factor regulator N-terminal
HIMGIKDF_01005 5.5e-86 sigM K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_01006 1.5e-191 yhdN C Aldo keto reductase
HIMGIKDF_01007 3e-110 plsC 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIMGIKDF_01008 3.1e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HIMGIKDF_01009 4.1e-74 cueR K transcriptional
HIMGIKDF_01010 1.4e-223 yhdR 2.6.1.1 E Aminotransferase
HIMGIKDF_01011 1.1e-240 corC1 P COG1253 Hemolysins and related proteins containing CBS domains
HIMGIKDF_01012 2.8e-47 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMGIKDF_01013 5.1e-66 crcB D Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HIMGIKDF_01014 3.3e-135 yhdW 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMGIKDF_01016 6.6e-204 yhdY M Mechanosensitive ion channel
HIMGIKDF_01017 1.2e-140 cobB K NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form
HIMGIKDF_01018 1.7e-151 yheN G deacetylase
HIMGIKDF_01019 1.1e-153 dat 2.6.1.21 E Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction
HIMGIKDF_01020 2.2e-233 nhaC C Na H antiporter
HIMGIKDF_01021 3.4e-84 nhaX T Belongs to the universal stress protein A family
HIMGIKDF_01022 0.0 yheI V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMGIKDF_01023 0.0 yheH V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMGIKDF_01024 3.7e-111 yheG GM NAD(P)H-binding
HIMGIKDF_01025 6.3e-28 sspB S spore protein
HIMGIKDF_01026 1.3e-36 yheE S Family of unknown function (DUF5342)
HIMGIKDF_01027 1.6e-268 gshB 6.3.2.2, 6.3.2.3 HJ YheC/D like ATP-grasp
HIMGIKDF_01028 4.3e-216 yheC HJ YheC/D like ATP-grasp
HIMGIKDF_01029 6.7e-204 yheB S Belongs to the UPF0754 family
HIMGIKDF_01030 9.5e-48 yheA S Belongs to the UPF0342 family
HIMGIKDF_01031 3.1e-206 yhaZ L DNA alkylation repair enzyme
HIMGIKDF_01032 4.3e-142 yhaX S haloacid dehalogenase-like hydrolase
HIMGIKDF_01033 7.1e-294 hemZ H coproporphyrinogen III oxidase
HIMGIKDF_01034 1.7e-208 yhaU P COG0475 Kef-type K transport systems, membrane components
HIMGIKDF_01035 7.8e-88 yhaT P regulatory, ligand-binding protein related to C-terminal domains of K channels
HIMGIKDF_01037 1.9e-133 yhaR 5.3.3.18 I enoyl-CoA hydratase
HIMGIKDF_01038 1.1e-26 S YhzD-like protein
HIMGIKDF_01039 1.8e-167 yhaQ S ABC transporter, ATP-binding protein
HIMGIKDF_01040 4.2e-215 yhaP CP COG1668 ABC-type Na efflux pump, permease component
HIMGIKDF_01041 3.6e-227 yhaO L DNA repair exonuclease
HIMGIKDF_01042 0.0 yhaN L AAA domain
HIMGIKDF_01043 1.5e-177 yhaM L Shows a 3'-5' exoribonuclease activity
HIMGIKDF_01044 1.6e-21 yhaL S Sporulation protein YhaL
HIMGIKDF_01045 1.9e-121 prsA 5.2.1.8 M plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HIMGIKDF_01046 8.7e-90 yhaK S Putative zincin peptidase
HIMGIKDF_01047 1.3e-54 yhaI S Protein of unknown function (DUF1878)
HIMGIKDF_01048 1e-113 hpr K Negative regulator of protease production and sporulation
HIMGIKDF_01049 7e-39 yhaH S YtxH-like protein
HIMGIKDF_01050 3.6e-80 trpP S Tryptophan transporter TrpP
HIMGIKDF_01051 9.9e-205 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HIMGIKDF_01052 4.7e-81 hit FG COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
HIMGIKDF_01053 4.6e-137 ecsA V transporter (ATP-binding protein)
HIMGIKDF_01054 1.8e-215 ecsB U ABC transporter
HIMGIKDF_01055 4.8e-115 ecsC S EcsC protein family
HIMGIKDF_01056 2.3e-231 yhaA 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
HIMGIKDF_01057 4.2e-248 yhfA C membrane
HIMGIKDF_01058 5.4e-10 1.15.1.2 C Rubrerythrin
HIMGIKDF_01059 1.3e-90 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HIMGIKDF_01060 0.0 pbpF 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMGIKDF_01061 1.7e-204 hemE 4.1.1.37 H Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HIMGIKDF_01062 7.3e-180 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
HIMGIKDF_01063 1.7e-268 hemG 1.14.19.9, 1.3.3.15, 1.3.3.4 H Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HIMGIKDF_01064 1.4e-101 yhgD K Transcriptional regulator
HIMGIKDF_01065 1e-238 yhgE S YhgE Pip N-terminal domain protein
HIMGIKDF_01066 3e-184 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIMGIKDF_01067 9.8e-138 yhfC S Putative membrane peptidase family (DUF2324)
HIMGIKDF_01068 1.6e-199 yhfE 3.2.1.4 GH5,GH9 G peptidase M42
HIMGIKDF_01069 1.7e-72 3.4.13.21 S ASCH
HIMGIKDF_01070 3.8e-227 gltP C Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HIMGIKDF_01071 1.8e-141 yhfI S COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III
HIMGIKDF_01072 2e-191 lplJ 6.3.1.20 H Lipoate-protein ligase
HIMGIKDF_01073 2.6e-112 yhfK GM NmrA-like family
HIMGIKDF_01074 7.3e-302 fadD 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HIMGIKDF_01075 1.9e-65 yhfM
HIMGIKDF_01076 5.4e-242 yhfN 3.4.24.84 O Peptidase M48
HIMGIKDF_01077 2.3e-204 aprE 3.4.21.62 O Belongs to the peptidase S8 family
HIMGIKDF_01078 9.2e-80 VY92_01935 K acetyltransferase
HIMGIKDF_01079 8.3e-182 yhfP 1.1.1.1 C Quinone oxidoreductase
HIMGIKDF_01080 4.3e-159 yfmC M Periplasmic binding protein
HIMGIKDF_01081 1.9e-109 yhfR 3.1.3.73 G Belongs to the phosphoglycerate mutase family
HIMGIKDF_01082 2.3e-201 vraB 2.3.1.9 I Belongs to the thiolase family
HIMGIKDF_01083 1e-281 yhfT 6.2.1.3 IQ AMP-binding enzyme C-terminal domain
HIMGIKDF_01084 5e-91 bioY S BioY family
HIMGIKDF_01085 1.7e-182 hemAT NT chemotaxis protein
HIMGIKDF_01086 1.1e-302 yhfW CE COG0665 Glycine D-amino acid oxidases (deaminating)
HIMGIKDF_01087 1.6e-157 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_01088 1.3e-32 yhzC S IDEAL
HIMGIKDF_01089 4.2e-109 comK K Competence transcription factor
HIMGIKDF_01090 2.1e-168 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_01091 7.8e-42 yhjA S Excalibur calcium-binding domain
HIMGIKDF_01092 6.1e-266 yhjB E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMGIKDF_01093 6.9e-27 yhjC S Protein of unknown function (DUF3311)
HIMGIKDF_01094 5e-60 yhjD
HIMGIKDF_01095 9.1e-110 yhjE S SNARE associated Golgi protein
HIMGIKDF_01096 1.2e-91 sipV 3.4.21.89 U Belongs to the peptidase S26 family
HIMGIKDF_01097 1.1e-286 yhjG CH FAD binding domain
HIMGIKDF_01098 1.2e-94 yhjH K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_01099 6.9e-215 glcP G Major Facilitator Superfamily
HIMGIKDF_01100 1.1e-200 thuB 1.1.1.361 S Oxidoreductase family, C-terminal alpha/beta domain
HIMGIKDF_01101 1.8e-161 ntdB 3.1.3.92 S Sucrose-6F-phosphate phosphohydrolase
HIMGIKDF_01102 4.4e-255 ntdA 2.6.1.104 E Belongs to the DegT DnrJ EryC1 family
HIMGIKDF_01103 7e-189 yhjM 5.1.1.1 K Transcriptional regulator
HIMGIKDF_01104 3.8e-202 abrB S membrane
HIMGIKDF_01105 3.1e-215 EGP Transmembrane secretion effector
HIMGIKDF_01106 0.0 S Sugar transport-related sRNA regulator N-term
HIMGIKDF_01107 2e-36 yhjQ C COG1145 Ferredoxin
HIMGIKDF_01108 2.2e-78 yhjR S Rubrerythrin
HIMGIKDF_01109 0.0 addB 3.1.21.3, 3.6.4.12 L ATP-dependent helicase deoxyribonuclease subunit B
HIMGIKDF_01110 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HIMGIKDF_01111 1.7e-221 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HIMGIKDF_01112 0.0 sbcC L COG0419 ATPase involved in DNA repair
HIMGIKDF_01113 6e-51 yisB V COG1403 Restriction endonuclease
HIMGIKDF_01114 4.5e-32 gerPF S Spore germination protein gerPA/gerPF
HIMGIKDF_01115 3e-66 gerPE S Spore germination protein GerPE
HIMGIKDF_01116 6.3e-24 gerPD S Spore germination protein
HIMGIKDF_01117 1.8e-54 gerPC S Spore germination protein
HIMGIKDF_01118 4e-34 gerPB S cell differentiation
HIMGIKDF_01119 1.9e-33 gerPA S Spore germination protein
HIMGIKDF_01120 1.5e-22 yisI S Spo0E like sporulation regulatory protein
HIMGIKDF_01121 1.7e-176 cotH M Spore Coat
HIMGIKDF_01122 3.2e-172 yisK Q COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)
HIMGIKDF_01123 3e-57 yisL S UPF0344 protein
HIMGIKDF_01124 0.0 wprA O Belongs to the peptidase S8 family
HIMGIKDF_01125 7.2e-106 yisN S Protein of unknown function (DUF2777)
HIMGIKDF_01126 0.0 asnO 6.3.5.4 E Asparagine synthase
HIMGIKDF_01127 2.1e-88 yizA S Damage-inducible protein DinB
HIMGIKDF_01128 6.8e-150 crtB 2.5.1.21, 2.5.1.32, 2.5.1.99 I phytoene
HIMGIKDF_01129 4e-243 yisQ V Mate efflux family protein
HIMGIKDF_01130 1.4e-161 yisR K Transcriptional regulator
HIMGIKDF_01131 2.4e-184 purR K helix_turn _helix lactose operon repressor
HIMGIKDF_01132 4.5e-199 yisS 1.1.1.370 S Oxidoreductase family, C-terminal alpha/beta domain
HIMGIKDF_01133 1.3e-93 yisT S DinB family
HIMGIKDF_01134 6.4e-108 argO S Lysine exporter protein LysE YggA
HIMGIKDF_01135 1.7e-281 yisV K COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
HIMGIKDF_01136 4e-36 mcbG S Pentapeptide repeats (9 copies)
HIMGIKDF_01137 3.1e-155 yisY I hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIMGIKDF_01138 4.9e-113 cysC 1.8.4.10, 1.8.4.8, 2.7.1.25, 2.7.7.4 P Catalyzes the synthesis of activated sulfate
HIMGIKDF_01139 3.2e-233 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HIMGIKDF_01140 9.2e-143 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HIMGIKDF_01141 4.9e-125 comB 3.1.3.71 H Belongs to the ComB family
HIMGIKDF_01142 1.9e-141 yitD 4.4.1.19 S synthase
HIMGIKDF_01143 1.7e-108 yitE S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMGIKDF_01144 5.4e-222 yitF 5.5.1.27 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HIMGIKDF_01145 4e-229 yitG EGP Major facilitator Superfamily
HIMGIKDF_01146 1.8e-161 yitH K Acetyltransferase (GNAT) domain
HIMGIKDF_01147 2e-82 yjcF S Acetyltransferase (GNAT) domain
HIMGIKDF_01148 0.0 yitJ 1.5.1.20, 2.1.1.10, 2.1.1.13 E Catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine
HIMGIKDF_01149 8.6e-55 yajQ S Belongs to the UPF0234 family
HIMGIKDF_01150 4e-161 cvfB S protein conserved in bacteria
HIMGIKDF_01151 8.5e-94
HIMGIKDF_01152 2.8e-171
HIMGIKDF_01153 1.5e-97 S Sporulation delaying protein SdpA
HIMGIKDF_01154 1.5e-58 K Transcriptional regulator PadR-like family
HIMGIKDF_01155 2e-95
HIMGIKDF_01156 1.4e-44 yitR S Domain of unknown function (DUF3784)
HIMGIKDF_01157 2.2e-311 nprB 3.4.24.28 E Peptidase M4
HIMGIKDF_01158 8.4e-159 yitS S protein conserved in bacteria
HIMGIKDF_01159 6.6e-148 yitT S Uncharacterized protein conserved in bacteria (DUF2179)
HIMGIKDF_01160 1.9e-72 ipi S Intracellular proteinase inhibitor
HIMGIKDF_01161 1.2e-17 S Protein of unknown function (DUF3813)
HIMGIKDF_01162 1.9e-155 yitU 3.1.3.104 S hydrolases of the HAD superfamily
HIMGIKDF_01163 4.5e-143 yjfP S COG1073 Hydrolases of the alpha beta superfamily
HIMGIKDF_01164 4.7e-51 yitW S metal-sulfur cluster biosynthetic enzyme
HIMGIKDF_01165 1.5e-22 pilT S Proteolipid membrane potential modulator
HIMGIKDF_01166 4.3e-272 yitY C D-arabinono-1,4-lactone oxidase
HIMGIKDF_01167 1.7e-88 norB G Major Facilitator Superfamily
HIMGIKDF_01168 5.4e-200 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HIMGIKDF_01169 3.1e-231 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HIMGIKDF_01170 2.2e-137 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
HIMGIKDF_01171 4.4e-219 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
HIMGIKDF_01172 3.9e-206 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMGIKDF_01173 0.0 carB 6.3.5.5 EF Carbamoyl-phosphate synthetase ammonia chain
HIMGIKDF_01174 3.8e-176 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HIMGIKDF_01175 9.5e-28 yjzC S YjzC-like protein
HIMGIKDF_01176 2.3e-16 yjzD S Protein of unknown function (DUF2929)
HIMGIKDF_01177 6.2e-142 yjaU I carboxylic ester hydrolase activity
HIMGIKDF_01178 7.3e-103 yjaV
HIMGIKDF_01179 1.1e-183 med S Transcriptional activator protein med
HIMGIKDF_01180 7.3e-26 comZ S ComZ
HIMGIKDF_01181 2.7e-22 yjzB
HIMGIKDF_01182 3.9e-173 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HIMGIKDF_01183 1.8e-234 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMGIKDF_01184 7.8e-151 yjaZ O Zn-dependent protease
HIMGIKDF_01185 1.8e-184 appD P Belongs to the ABC transporter superfamily
HIMGIKDF_01186 6.5e-187 appF E Belongs to the ABC transporter superfamily
HIMGIKDF_01187 3.5e-48 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HIMGIKDF_01188 1.9e-190 appA E COG0747 ABC-type dipeptide transport system, periplasmic component
HIMGIKDF_01189 1.3e-171 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01190 7.9e-163 appC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01191 5e-147 yjbA S Belongs to the UPF0736 family
HIMGIKDF_01192 6.1e-185 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
HIMGIKDF_01193 0.0 oppA E ABC transporter substrate-binding protein
HIMGIKDF_01194 2.7e-166 oppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01195 7.7e-166 oppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01196 3e-198 oppD P Belongs to the ABC transporter superfamily
HIMGIKDF_01197 5.5e-172 oppF E Belongs to the ABC transporter superfamily
HIMGIKDF_01198 8.6e-196 yjbB EGP Major Facilitator Superfamily
HIMGIKDF_01199 6.9e-104 yjbC K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_01200 2.1e-67 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HIMGIKDF_01201 6e-112 yjbE P Integral membrane protein TerC family
HIMGIKDF_01202 2.3e-116 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIMGIKDF_01203 2.3e-223 yjbF S Competence protein
HIMGIKDF_01204 0.0 pepF E oligoendopeptidase F
HIMGIKDF_01205 1.8e-20
HIMGIKDF_01207 3.3e-169 yjbH Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HIMGIKDF_01208 3.7e-72 yjbI S Bacterial-like globin
HIMGIKDF_01209 1.5e-87 yjbJ M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIMGIKDF_01210 2.4e-101 yjbK S protein conserved in bacteria
HIMGIKDF_01211 7.1e-62 yjbL S Belongs to the UPF0738 family
HIMGIKDF_01212 2.6e-112 yjbM 2.7.6.5 S GTP pyrophosphokinase
HIMGIKDF_01213 2.1e-151 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMGIKDF_01214 9.5e-161 yjbO 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMGIKDF_01215 3e-128 prpE 3.1.3.16, 3.6.1.41 T Asymmetrically hydrolyzes Ap4p to yield AMP and ATP
HIMGIKDF_01216 0.0 yjbQ P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HIMGIKDF_01217 3.4e-137 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HIMGIKDF_01218 3.8e-108 tenI 2.5.1.3, 5.3.99.10 H Transcriptional regulator TenI
HIMGIKDF_01219 7.2e-219 thiO 1.4.3.19 E Glycine oxidase
HIMGIKDF_01220 3e-30 thiS H thiamine diphosphate biosynthetic process
HIMGIKDF_01221 1.5e-135 thiG 2.8.1.10 H Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
HIMGIKDF_01222 6e-188 thiF 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIMGIKDF_01223 5.3e-150 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMGIKDF_01224 3.2e-141 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HIMGIKDF_01225 5.9e-54 yjbX S Spore coat protein
HIMGIKDF_01226 5.2e-83 cotZ S Spore coat protein
HIMGIKDF_01227 3.4e-96 cotY S Spore coat protein Z
HIMGIKDF_01228 6.4e-77 cotX S Spore Coat Protein X and V domain
HIMGIKDF_01229 3e-32 cotW
HIMGIKDF_01230 2.3e-55 cotV S Spore Coat Protein X and V domain
HIMGIKDF_01231 8.7e-57 yjcA S Protein of unknown function (DUF1360)
HIMGIKDF_01234 2.9e-38 spoVIF S Stage VI sporulation protein F
HIMGIKDF_01235 0.0 yjcD 3.6.4.12 L DNA helicase
HIMGIKDF_01236 1.7e-38
HIMGIKDF_01237 3e-72 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_01238 2.9e-93 yjcG J Belongs to the 2H phosphoesterase superfamily. YjcG family
HIMGIKDF_01239 1.8e-138 yjcH P COG2382 Enterochelin esterase and related enzymes
HIMGIKDF_01240 3.8e-215 metB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMGIKDF_01241 2.9e-218 metC 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMGIKDF_01242 3.7e-99 rimJ 2.3.1.128 J Alanine acetyltransferase
HIMGIKDF_01243 1.1e-212 yjcL S Protein of unknown function (DUF819)
HIMGIKDF_01246 2.1e-190 S Putative amidase domain
HIMGIKDF_01247 2.6e-44 yjcN
HIMGIKDF_01250 8.5e-81 L Transposase
HIMGIKDF_01251 1.6e-72 yjcP
HIMGIKDF_01252 4.1e-49 S YjcQ protein
HIMGIKDF_01253 1.1e-92 yqaS L DNA packaging
HIMGIKDF_01254 2.2e-47 yjcS S Antibiotic biosynthesis monooxygenase
HIMGIKDF_01255 2.4e-141 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_01257 0.0 manR 2.7.1.200, 2.7.1.202 GKT transcriptional antiterminator
HIMGIKDF_01258 0.0 manP 2.7.1.191, 2.7.1.202 G phosphotransferase system
HIMGIKDF_01259 6.7e-189 manA 5.3.1.8 G mannose-6-phosphate isomerase
HIMGIKDF_01260 4.8e-51 yjdF S Protein of unknown function (DUF2992)
HIMGIKDF_01261 2.5e-94 yjdG 2.3.1.128 J Acetyltransferase (GNAT) domain
HIMGIKDF_01263 8e-82 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HIMGIKDF_01264 4.2e-29 S Domain of unknown function (DUF4177)
HIMGIKDF_01265 2.7e-52 yjdJ S Domain of unknown function (DUF4306)
HIMGIKDF_01266 3.3e-175 cyoE 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIMGIKDF_01268 4.9e-265 xynD 3.5.1.104 G Polysaccharide deacetylase
HIMGIKDF_01269 5.5e-83 S Protein of unknown function (DUF2690)
HIMGIKDF_01270 3.6e-21 yjfB S Putative motility protein
HIMGIKDF_01271 1.6e-171 yjfC O Predicted Zn-dependent protease (DUF2268)
HIMGIKDF_01272 1.2e-45 T PhoQ Sensor
HIMGIKDF_01273 8.9e-104 yjgB S Domain of unknown function (DUF4309)
HIMGIKDF_01274 0.0 yjgC 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HIMGIKDF_01275 4.3e-95 yjgD S Protein of unknown function (DUF1641)
HIMGIKDF_01276 8.7e-07 S Domain of unknown function (DUF4352)
HIMGIKDF_01277 2e-117 yjhB 3.6.1.13, 3.6.1.55 F ADP-ribose pyrophosphatase
HIMGIKDF_01279 3.8e-226 yjiB 1.14.13.154, 1.14.15.8 C Cytochrome P450
HIMGIKDF_01280 4.5e-219 oleD GT1 CG COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase
HIMGIKDF_01281 8.2e-30
HIMGIKDF_01282 1.2e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HIMGIKDF_01283 1.9e-122 ybbM S transport system, permease component
HIMGIKDF_01284 5.2e-136 pstB 3.6.3.27 P ATPases associated with a variety of cellular activities
HIMGIKDF_01285 1.8e-176 yjlA EG Putative multidrug resistance efflux transporter
HIMGIKDF_01286 2.8e-93 yjlB S Cupin domain
HIMGIKDF_01287 7.1e-66 yjlC S Protein of unknown function (DUF1641)
HIMGIKDF_01288 2.6e-219 yjlD 1.6.99.3 C NADH dehydrogenase
HIMGIKDF_01289 6.3e-284 uxaC 5.3.1.12 G glucuronate isomerase
HIMGIKDF_01290 5.8e-250 yjmB G symporter YjmB
HIMGIKDF_01291 3e-195 yjmC 1.1.1.350 C Belongs to the LDH2 MDH2 oxidoreductase family
HIMGIKDF_01292 1.6e-193 rspB 1.1.1.380 E Alcohol dehydrogenase GroES-like domain
HIMGIKDF_01293 4.7e-215 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HIMGIKDF_01294 2.3e-153 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_01295 3.7e-227 exuT G Sugar (and other) transporter
HIMGIKDF_01296 2.3e-184 exuR K transcriptional
HIMGIKDF_01297 2.1e-287 uxaB 1.1.1.17, 1.1.1.58 G tagaturonate reductase activity
HIMGIKDF_01298 2e-288 uxaA 4.2.1.7, 4.4.1.24 G Altronate
HIMGIKDF_01299 4.3e-130 MA20_18170 S membrane transporter protein
HIMGIKDF_01300 3.3e-80 yjoA S DinB family
HIMGIKDF_01301 9.4e-247 ftsH2 3.4.21.53 O AAA domain (dynein-related subfamily)
HIMGIKDF_01302 2.1e-213 S response regulator aspartate phosphatase
HIMGIKDF_01304 6.3e-41 S YCII-related domain
HIMGIKDF_01305 9.1e-170 xlyA 3.5.1.28 CBM50 M N-acetylmuramoyl-L-alanine amidase
HIMGIKDF_01306 2.1e-61 yjqA S Bacterial PH domain
HIMGIKDF_01307 4.2e-112 yjqB S Pfam:DUF867
HIMGIKDF_01308 4.4e-160 ydbD P Catalase
HIMGIKDF_01309 1.6e-111 xkdA E IrrE N-terminal-like domain
HIMGIKDF_01310 3.2e-56 xre K Helix-turn-helix XRE-family like proteins
HIMGIKDF_01312 5.9e-157 xkdB K sequence-specific DNA binding
HIMGIKDF_01313 6.4e-119 xkdC L Bacterial dnaA protein
HIMGIKDF_01316 4.6e-10 yqaO S Phage-like element PBSX protein XtrA
HIMGIKDF_01317 4.4e-86 xpf K COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog
HIMGIKDF_01318 4.8e-140 xtmA L phage terminase small subunit
HIMGIKDF_01319 9.6e-255 xtmB S phage terminase, large subunit
HIMGIKDF_01320 5.4e-286 yqbA S portal protein
HIMGIKDF_01321 1.2e-133 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HIMGIKDF_01322 5.8e-169 xkdG S Phage capsid family
HIMGIKDF_01323 5.5e-65 yqbG S Protein of unknown function (DUF3199)
HIMGIKDF_01324 8.7e-65 yqbH S Domain of unknown function (DUF3599)
HIMGIKDF_01325 4.4e-88 xkdI S Bacteriophage HK97-gp10, putative tail-component
HIMGIKDF_01326 1.9e-77 xkdJ
HIMGIKDF_01327 2.5e-256 xkdK S Phage tail sheath C-terminal domain
HIMGIKDF_01328 6.1e-76 xkdM S Phage tail tube protein
HIMGIKDF_01329 1.9e-77 S Phage XkdN-like tail assembly chaperone protein, TAC
HIMGIKDF_01330 0.0 xkdO L Transglycosylase SLT domain
HIMGIKDF_01331 3.7e-122 xkdP S Lysin motif
HIMGIKDF_01332 4.8e-182 yqbQ 3.2.1.96 G NLP P60 protein
HIMGIKDF_01333 2.1e-39 xkdR S Protein of unknown function (DUF2577)
HIMGIKDF_01334 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HIMGIKDF_01335 1.2e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HIMGIKDF_01336 4e-104 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HIMGIKDF_01337 6.7e-41
HIMGIKDF_01338 0.0
HIMGIKDF_01339 2.6e-55 xkdW S XkdW protein
HIMGIKDF_01340 1.7e-23 xkdX
HIMGIKDF_01341 1.2e-154 xepA
HIMGIKDF_01342 2.8e-39 xhlA S Haemolysin XhlA
HIMGIKDF_01343 9.3e-40 xhlB S SPP1 phage holin
HIMGIKDF_01344 1.2e-163 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMGIKDF_01345 6.7e-23 spoIISB S Stage II sporulation protein SB
HIMGIKDF_01346 1.8e-136 spoIISA S Toxin SpoIISA, type II toxin-antitoxin system
HIMGIKDF_01347 5.8e-175 pit P phosphate transporter
HIMGIKDF_01348 6.9e-110 ykaA P COG1392 Phosphate transport regulator (distant homolog of PhoU)
HIMGIKDF_01349 9.4e-242 steT E amino acid
HIMGIKDF_01350 7.2e-183 mhqA E COG0346 Lactoylglutathione lyase and related lyases
HIMGIKDF_01352 0.0 ykcB M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIMGIKDF_01353 1.3e-179 ykcC GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMGIKDF_01355 8.5e-214 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMGIKDF_01356 1e-137 proG 1.5.1.2 E Pyrroline-5-carboxylate reductase
HIMGIKDF_01357 7.9e-154 dppA E D-aminopeptidase
HIMGIKDF_01358 1.1e-159 dppB P COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01359 3.9e-176 dppC EP COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components
HIMGIKDF_01360 3.4e-191 dppD P Belongs to the ABC transporter superfamily
HIMGIKDF_01361 0.0 dppE E ABC transporter substrate-binding protein
HIMGIKDF_01363 8.1e-179 ykfA 3.4.17.13 V proteins, homologs of microcin C7 resistance protein MccF
HIMGIKDF_01364 3.2e-203 ykfB 5.1.1.20 M Belongs to the mandelate racemase muconate lactonizing enzyme family
HIMGIKDF_01365 5.3e-172 ykfC 3.4.14.13 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIMGIKDF_01366 7.7e-188 ykfD E Belongs to the ABC transporter superfamily
HIMGIKDF_01367 7.4e-205 pgl 3.1.1.31 G 6-phosphogluconolactonase
HIMGIKDF_01368 5.3e-161 ykgA E Amidinotransferase
HIMGIKDF_01369 1.5e-92 ykhA 3.1.2.20 I Acyl-CoA hydrolase
HIMGIKDF_01370 1e-226 hmp 1.14.12.17 C Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HIMGIKDF_01371 1e-07
HIMGIKDF_01372 5.4e-130 ykjA S Protein of unknown function (DUF421)
HIMGIKDF_01373 1e-98 ykkA S Protein of unknown function (DUF664)
HIMGIKDF_01374 1e-98 ykkB 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIMGIKDF_01375 3.5e-55 ykkC P Multidrug resistance protein
HIMGIKDF_01376 1.1e-50 ykkD P Multidrug resistance protein
HIMGIKDF_01377 3.9e-170 purU 2.7.7.72, 3.5.1.10 F Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)
HIMGIKDF_01378 1e-201 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIMGIKDF_01379 2.5e-228 proA 1.2.1.41, 1.2.1.81 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HIMGIKDF_01380 1.3e-70 ohrA O Organic hydroperoxide resistance protein
HIMGIKDF_01381 3.9e-75 ohrR K COG1846 Transcriptional regulators
HIMGIKDF_01382 8.4e-72 ohrB O Organic hydroperoxide resistance protein
HIMGIKDF_01384 2.8e-87 guaD 3.5.4.12, 3.5.4.3, 3.5.4.33 FJ COG0590 Cytosine adenosine deaminases
HIMGIKDF_01385 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HIMGIKDF_01386 1.7e-176 isp O Belongs to the peptidase S8 family
HIMGIKDF_01387 6.3e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMGIKDF_01388 1.8e-136 ykoC P Cobalt transport protein
HIMGIKDF_01389 4.6e-311 P ABC transporter, ATP-binding protein
HIMGIKDF_01390 6.9e-99 ykoE S ABC-type cobalt transport system, permease component
HIMGIKDF_01391 7.9e-111 ykoF S YKOF-related Family
HIMGIKDF_01392 2.4e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_01393 9.4e-245 ykoH 2.7.13.3 T Histidine kinase
HIMGIKDF_01394 1.1e-113 ykoI S Peptidase propeptide and YPEB domain
HIMGIKDF_01395 4.4e-86 ykoJ S Peptidase propeptide and YPEB domain
HIMGIKDF_01398 2.2e-222 mgtE P Acts as a magnesium transporter
HIMGIKDF_01399 1.4e-53 tnrA K transcriptional
HIMGIKDF_01400 5.9e-18
HIMGIKDF_01401 6.9e-26 ykoL
HIMGIKDF_01402 1.3e-81 mhqR K transcriptional
HIMGIKDF_01403 2.3e-220 ugtP 2.4.1.315 GT28 M COG0707 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase
HIMGIKDF_01404 3.7e-99 ykoP G polysaccharide deacetylase
HIMGIKDF_01405 7.1e-155 ykoQ S Calcineurin-like phosphoesterase superfamily domain
HIMGIKDF_01406 0.0 ykoS
HIMGIKDF_01407 2.5e-186 ykoT GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMGIKDF_01408 0.0 ligD 6.5.1.1 L ATP-dependent DNA ligase
HIMGIKDF_01409 3.2e-161 ku L With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
HIMGIKDF_01410 0.0 ydcR 2.7.7.65 T Diguanylate cyclase
HIMGIKDF_01411 1.4e-116 ykoX S membrane-associated protein
HIMGIKDF_01412 2.1e-177 ykoY P COG0861 Membrane protein TerC, possibly involved in tellurium resistance
HIMGIKDF_01413 4.7e-129 sigI K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_01414 8.2e-117 rsgI S Anti-sigma factor N-terminus
HIMGIKDF_01415 1.9e-26 sspD S small acid-soluble spore protein
HIMGIKDF_01416 1.5e-124 ykrK S Domain of unknown function (DUF1836)
HIMGIKDF_01417 7e-156 htpX O Belongs to the peptidase M48B family
HIMGIKDF_01418 1.7e-233 ktrB P COG0168 Trk-type K transport systems, membrane components
HIMGIKDF_01419 1.2e-10 ydfR S Protein of unknown function (DUF421)
HIMGIKDF_01420 4.5e-22 ykzE
HIMGIKDF_01421 6.5e-190 ykrP G COG3594 Fucose 4-O-acetylase and related acetyltransferases
HIMGIKDF_01422 0.0 kinE 2.7.13.3 T Histidine kinase
HIMGIKDF_01423 7e-89 ogt 2.1.1.63 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HIMGIKDF_01425 3.3e-197 mtnA 5.3.1.23 E Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HIMGIKDF_01426 7.5e-230 mtnK 2.7.1.100 F Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
HIMGIKDF_01427 3.5e-151 mtnU 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
HIMGIKDF_01428 8e-232 mtnE 2.6.1.83 E Aminotransferase
HIMGIKDF_01429 4.1e-231 mtnW 5.3.2.5 G Catalyzes the enolization of 2,3-diketo-5- methylthiopentyl-1-phosphate (DK-MTP-1-P) into 2-hydroxy-3-keto-5- methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P)
HIMGIKDF_01430 7.5e-137 mtnX 3.1.3.87, 4.2.1.109 E Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HIMGIKDF_01431 7.2e-115 mtnB 3.1.3.87, 4.1.2.17, 4.2.1.109, 5.1.3.4 E Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P)
HIMGIKDF_01432 1.3e-96 mtnD 1.13.11.53, 1.13.11.54 S Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HIMGIKDF_01433 1.3e-51 XK27_09985 S Protein of unknown function (DUF1232)
HIMGIKDF_01434 6.4e-09 S Spo0E like sporulation regulatory protein
HIMGIKDF_01435 1.4e-64 eag
HIMGIKDF_01436 2.5e-275 kinD 2.7.13.3 T COG0642 Signal transduction histidine kinase
HIMGIKDF_01437 1.3e-75 ykvE K transcriptional
HIMGIKDF_01438 2.5e-125 motB N Flagellar motor protein
HIMGIKDF_01439 2.7e-138 motA N flagellar motor
HIMGIKDF_01440 0.0 clpE O Belongs to the ClpA ClpB family
HIMGIKDF_01441 8.7e-182 ykvI S membrane
HIMGIKDF_01442 7.3e-126 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HIMGIKDF_01443 2.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
HIMGIKDF_01444 1.3e-139 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
HIMGIKDF_01445 2e-96 queF 1.7.1.13 S Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HIMGIKDF_01446 2e-61 ykvN K Transcriptional regulator
HIMGIKDF_01447 8.2e-134 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_01448 4e-217 ykvP 3.5.1.28 M Glycosyl transferases group 1
HIMGIKDF_01449 1.2e-35 3.5.1.104 M LysM domain
HIMGIKDF_01450 8.5e-133 G Glycosyl hydrolases family 18
HIMGIKDF_01451 5.6e-46 ykvR S Protein of unknown function (DUF3219)
HIMGIKDF_01452 6e-25 ykvS S protein conserved in bacteria
HIMGIKDF_01453 2.8e-28
HIMGIKDF_01454 1.7e-103 ykvT 3.5.1.28 M Cell Wall Hydrolase
HIMGIKDF_01455 9.9e-239 ykvU S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_01456 4.9e-90 stoA CO thiol-disulfide
HIMGIKDF_01457 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HIMGIKDF_01458 3.8e-09
HIMGIKDF_01459 8.7e-209 pepQ 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HIMGIKDF_01461 9.8e-180 ykvZ 5.1.1.1 K Transcriptional regulator
HIMGIKDF_01463 4.5e-128 glcT K antiterminator
HIMGIKDF_01464 0.0 ptsG 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_01465 2.1e-39 ptsH G phosphocarrier protein HPr
HIMGIKDF_01466 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HIMGIKDF_01467 7.2e-39 splA S Transcriptional regulator
HIMGIKDF_01468 2.6e-202 splB 4.1.99.14 L Spore photoproduct lyase
HIMGIKDF_01469 1.2e-131 ykwB 2.3.1.1 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_01470 2e-264 mcpC NT chemotaxis protein
HIMGIKDF_01471 5e-159 glxR 1.1.1.31, 1.1.1.60 I COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases
HIMGIKDF_01472 8e-124 ykwD J protein with SCP PR1 domains
HIMGIKDF_01473 0.0 mrdA 3.4.16.4 M Penicillin-binding Protein
HIMGIKDF_01474 0.0 pilS 2.7.13.3 T Histidine kinase
HIMGIKDF_01475 8e-224 patA 2.6.1.1 E Aminotransferase
HIMGIKDF_01476 2.2e-15
HIMGIKDF_01477 1.6e-168 cheV 2.7.13.3 T Chemotaxis protein CheV
HIMGIKDF_01478 1.7e-84 ykyB S YkyB-like protein
HIMGIKDF_01479 1.6e-238 ykuC EGP Major facilitator Superfamily
HIMGIKDF_01480 4.6e-88 ykuD S protein conserved in bacteria
HIMGIKDF_01481 9.4e-166 ykuE S Metallophosphoesterase
HIMGIKDF_01482 2.2e-142 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_01483 0.0 3.2.1.132 M Putative peptidoglycan binding domain
HIMGIKDF_01484 1.7e-93 M Peptidoglycan-binding domain 1 protein
HIMGIKDF_01486 5.2e-234 ykuI T Diguanylate phosphodiesterase
HIMGIKDF_01487 3.9e-37 ykuJ S protein conserved in bacteria
HIMGIKDF_01488 4.4e-94 ykuK S Ribonuclease H-like
HIMGIKDF_01489 3.9e-27 ykzF S Antirepressor AbbA
HIMGIKDF_01490 1.6e-76 ykuL S CBS domain
HIMGIKDF_01491 3.5e-168 ccpC K Transcriptional regulator
HIMGIKDF_01492 5.7e-88 fld C Flavodoxin domain
HIMGIKDF_01493 3.2e-177 ykuO
HIMGIKDF_01494 3.2e-80 fld C Flavodoxin
HIMGIKDF_01495 1.1e-74 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
HIMGIKDF_01496 5.8e-216 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
HIMGIKDF_01497 9e-37 ykuS S Belongs to the UPF0180 family
HIMGIKDF_01498 8.8e-142 ykuT M Mechanosensitive ion channel
HIMGIKDF_01499 3.9e-101 ykuU O Alkyl hydroperoxide reductase
HIMGIKDF_01500 4.4e-82 ykuV CO thiol-disulfide
HIMGIKDF_01501 5.8e-95 rok K Repressor of ComK
HIMGIKDF_01502 2.9e-147 yknT
HIMGIKDF_01503 3.9e-110 mobA 2.7.7.77 H Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
HIMGIKDF_01504 5.3e-192 moeB 2.7.7.73, 2.7.7.80 H COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2
HIMGIKDF_01505 8.1e-246 moeA 2.10.1.1 H molybdopterin
HIMGIKDF_01506 9.9e-94 mobB 2.10.1.1, 2.7.7.77 H molybdopterin-guanine dinucleotide biosynthesis protein
HIMGIKDF_01507 8.5e-84 moaE 2.8.1.12 H COG0314 Molybdopterin converting factor, large subunit
HIMGIKDF_01508 2.8e-32 moaD 2.8.1.12 H Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HIMGIKDF_01509 0.0 yknU V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMGIKDF_01510 0.0 yknV V COG1132 ABC-type multidrug transport system, ATPase and permease components
HIMGIKDF_01511 1e-117 yknW S Yip1 domain
HIMGIKDF_01512 3e-159 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HIMGIKDF_01513 2.5e-124 macB V ABC transporter, ATP-binding protein
HIMGIKDF_01514 2.1e-211 yknZ V COG0577 ABC-type antimicrobial peptide transport system, permease component
HIMGIKDF_01515 3.1e-136 fruR K Transcriptional regulator
HIMGIKDF_01516 6.2e-168 fruK 2.7.1.11, 2.7.1.56 G Belongs to the carbohydrate kinase PfkB family
HIMGIKDF_01517 0.0 fruA 2.7.1.202 GT COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type)
HIMGIKDF_01518 4.8e-105 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMGIKDF_01519 8.1e-39 ykoA
HIMGIKDF_01520 5.8e-310 ybiT S COG0488 ATPase components of ABC transporters with duplicated ATPase domains
HIMGIKDF_01521 1.5e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMGIKDF_01522 2e-238 ampS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
HIMGIKDF_01523 1.1e-12 S Uncharacterized protein YkpC
HIMGIKDF_01524 7.7e-183 mreB D Rod-share determining protein MreBH
HIMGIKDF_01525 1.5e-43 abrB K of stationary sporulation gene expression
HIMGIKDF_01526 2.7e-241 kinC 2.7.13.3 T COG0642 Signal transduction histidine kinase
HIMGIKDF_01527 1.6e-162 ykqA P Gamma-glutamyl cyclotransferase, AIG2-like
HIMGIKDF_01528 4e-116 ktrA P COG0569 K transport systems, NAD-binding component
HIMGIKDF_01529 0.0 ade 3.5.4.2 F Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HIMGIKDF_01530 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMGIKDF_01531 8.2e-31 ykzG S Belongs to the UPF0356 family
HIMGIKDF_01532 1.4e-147 ykrA S hydrolases of the HAD superfamily
HIMGIKDF_01533 4e-101 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMGIKDF_01535 2e-115 recN L Putative cell-wall binding lipoprotein
HIMGIKDF_01536 9.9e-192 pdhA 1.2.4.1, 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMGIKDF_01537 2.9e-179 pdhB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMGIKDF_01538 9.9e-231 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMGIKDF_01539 2.4e-243 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMGIKDF_01540 6.6e-60 slp CO COG0526, thiol-disulfide isomerase and thioredoxins
HIMGIKDF_01541 3.5e-277 speA 4.1.1.19 E Arginine
HIMGIKDF_01542 1.6e-42 yktA S Belongs to the UPF0223 family
HIMGIKDF_01543 7.1e-118 yktB S Belongs to the UPF0637 family
HIMGIKDF_01544 7.1e-26 ykzI
HIMGIKDF_01545 4.6e-151 suhB 3.1.3.25 G Inositol monophosphatase
HIMGIKDF_01546 6.9e-78 ykzC S Acetyltransferase (GNAT) family
HIMGIKDF_01547 6.5e-173 Q Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
HIMGIKDF_01548 2.2e-293 mpl 3.4.24.28, 3.4.24.29 E Peptidase M4
HIMGIKDF_01549 0.0 ylaA
HIMGIKDF_01550 2.7e-42 ylaB
HIMGIKDF_01551 2.7e-91 ylaC K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_01552 1.2e-11 sigC S Putative zinc-finger
HIMGIKDF_01553 1.8e-38 ylaE
HIMGIKDF_01554 8.2e-22 S Family of unknown function (DUF5325)
HIMGIKDF_01555 0.0 typA T GTP-binding protein TypA
HIMGIKDF_01556 4.2e-47 ylaH S YlaH-like protein
HIMGIKDF_01557 2.5e-32 ylaI S protein conserved in bacteria
HIMGIKDF_01558 1.1e-89 ylaJ S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMGIKDF_01559 8e-249 phoH T ATPase related to phosphate starvation-inducible protein PhoH
HIMGIKDF_01560 2.7e-85 ylaL S Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HIMGIKDF_01561 1.6e-171 glsA 3.5.1.2 E Belongs to the glutaminase family
HIMGIKDF_01562 8.7e-44 ylaN S Belongs to the UPF0358 family
HIMGIKDF_01563 4.5e-214 ftsW D Belongs to the SEDS family
HIMGIKDF_01564 0.0 pyc 6.4.1.1 C Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HIMGIKDF_01565 2.6e-166 ctaA 2.5.1.141 O Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group
HIMGIKDF_01566 3.2e-164 ctaB 2.5.1.141 O Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
HIMGIKDF_01567 6.2e-191 ctaC 1.9.3.1 C Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
HIMGIKDF_01568 0.0 ctaD 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIMGIKDF_01569 3.3e-112 cyoC 1.10.3.12, 1.9.3.1 C COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3
HIMGIKDF_01570 4.2e-53 ctaF 1.10.3.12, 1.9.3.1 C COG3125 Heme copper-type cytochrome quinol oxidase, subunit 4
HIMGIKDF_01571 3e-167 ctaG S cytochrome c oxidase
HIMGIKDF_01572 7e-62 ylbA S YugN-like family
HIMGIKDF_01573 2.6e-74 ylbB T COG0517 FOG CBS domain
HIMGIKDF_01574 3e-201 ylbC S protein with SCP PR1 domains
HIMGIKDF_01575 4.1e-63 ylbD S Putative coat protein
HIMGIKDF_01576 6.7e-37 ylbE S YlbE-like protein
HIMGIKDF_01577 1.8e-75 ylbF S Belongs to the UPF0342 family
HIMGIKDF_01578 7.5e-39 ylbG S UPF0298 protein
HIMGIKDF_01579 1.9e-98 rsmD 2.1.1.171 L Methyltransferase
HIMGIKDF_01580 3.9e-84 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HIMGIKDF_01581 3.8e-221 ylbJ S Sporulation integral membrane protein YlbJ
HIMGIKDF_01582 7.5e-138 ylbK S esterase of the alpha-beta hydrolase superfamily
HIMGIKDF_01583 6.8e-187 ylbL T Belongs to the peptidase S16 family
HIMGIKDF_01584 2.8e-235 ylbM S Belongs to the UPF0348 family
HIMGIKDF_01586 1.3e-90 yceD S metal-binding, possibly nucleic acid-binding protein
HIMGIKDF_01587 1.2e-27 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HIMGIKDF_01588 6.8e-75 ylbO S SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
HIMGIKDF_01589 4e-89 ylbP K n-acetyltransferase
HIMGIKDF_01590 7.3e-169 panE 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HIMGIKDF_01591 2.9e-309 bshC S Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
HIMGIKDF_01592 2.9e-78 mraZ K Belongs to the MraZ family
HIMGIKDF_01593 6.6e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HIMGIKDF_01594 3.7e-44 ftsL D Essential cell division protein
HIMGIKDF_01595 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HIMGIKDF_01596 0.0 ftsI 3.4.16.4 M stage V sporulation protein D
HIMGIKDF_01597 5.2e-281 murE 6.3.2.10, 6.3.2.13 M Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HIMGIKDF_01598 3.2e-170 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HIMGIKDF_01599 2.6e-255 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HIMGIKDF_01600 5.7e-186 spoVE D Belongs to the SEDS family
HIMGIKDF_01601 2.3e-201 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HIMGIKDF_01602 5.3e-167 murB 1.3.1.98 M cell wall formation
HIMGIKDF_01603 2.6e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HIMGIKDF_01604 2.4e-103 ylxW S protein conserved in bacteria
HIMGIKDF_01605 1e-102 ylxX S protein conserved in bacteria
HIMGIKDF_01606 6.2e-58 sbp S small basic protein
HIMGIKDF_01607 2.4e-229 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HIMGIKDF_01608 2e-203 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HIMGIKDF_01609 0.0 bpr O COG1404 Subtilisin-like serine proteases
HIMGIKDF_01610 4.4e-172 spoIIGA M aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR
HIMGIKDF_01611 1.4e-125 sigE K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_01612 3.6e-140 sigG K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_01613 1.1e-147 modF 3.6.3.21, 3.6.3.34 P COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA
HIMGIKDF_01614 1.3e-256 argE 3.5.1.16 E Acetylornithine deacetylase
HIMGIKDF_01615 2.4e-37 ylmC S sporulation protein
HIMGIKDF_01616 1.1e-158 yfiH S Belongs to the multicopper oxidase YfiH RL5 family
HIMGIKDF_01617 2.9e-125 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HIMGIKDF_01618 3.3e-61 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HIMGIKDF_01619 1.3e-39 yggT S membrane
HIMGIKDF_01620 6.7e-139 ylmH 5.4.99.23, 5.4.99.24 S conserved protein, contains S4-like domain
HIMGIKDF_01621 2.6e-67 divIVA D Cell division initiation protein
HIMGIKDF_01622 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HIMGIKDF_01623 1.3e-63 dksA T COG1734 DnaK suppressor protein
HIMGIKDF_01624 1.8e-78 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HIMGIKDF_01625 1.2e-163 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HIMGIKDF_01626 2.7e-94 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HIMGIKDF_01627 9e-232 pyrP F Xanthine uracil
HIMGIKDF_01628 1.4e-167 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
HIMGIKDF_01629 1.7e-251 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
HIMGIKDF_01630 5e-212 carA 6.3.5.5 F Carbamoyl-phosphate synthetase glutamine chain
HIMGIKDF_01631 0.0 carB 6.3.5.5 F Belongs to the CarB family
HIMGIKDF_01632 4.8e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
HIMGIKDF_01633 2.9e-176 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
HIMGIKDF_01634 8e-126 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HIMGIKDF_01635 2.9e-116 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HIMGIKDF_01637 3.5e-142 cysH 1.8.4.10, 1.8.4.8, 2.7.1.25 EH Belongs to the PAPS reductase family. CysH subfamily
HIMGIKDF_01638 1.1e-179 cysP P phosphate transporter
HIMGIKDF_01639 1.3e-223 sat 2.7.7.4 P Belongs to the sulfate adenylyltransferase family
HIMGIKDF_01640 7.3e-109 cysC 2.7.1.25 P Catalyzes the synthesis of activated sulfate
HIMGIKDF_01641 2.2e-145 hemD 2.1.1.107, 4.2.1.75 H Belongs to the precorrin methyltransferase family
HIMGIKDF_01642 2e-146 cbiX 4.99.1.3, 4.99.1.4, 5.4.99.60, 5.4.99.61 S Sirohydrochlorin ferrochelatase
HIMGIKDF_01643 4.3e-83 cysG 1.3.1.76, 4.99.1.4 H Siroheme synthase
HIMGIKDF_01644 0.0 FbpA K RNA-binding protein homologous to eukaryotic snRNP
HIMGIKDF_01645 0.0 yloB 3.6.3.8 P COG0474 Cation transport ATPase
HIMGIKDF_01646 2.4e-156 yloC S stress-induced protein
HIMGIKDF_01647 1.5e-40 ylzA S Belongs to the UPF0296 family
HIMGIKDF_01648 3.1e-110 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HIMGIKDF_01649 2.2e-28 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HIMGIKDF_01650 8.8e-226 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HIMGIKDF_01651 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HIMGIKDF_01652 6e-85 def 2.1.2.9, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HIMGIKDF_01653 3.8e-176 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HIMGIKDF_01654 2.9e-254 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HIMGIKDF_01655 4.8e-207 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HIMGIKDF_01656 2.4e-141 stp 3.1.3.16 T phosphatase
HIMGIKDF_01657 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HIMGIKDF_01658 8.6e-170 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HIMGIKDF_01659 4.2e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HIMGIKDF_01660 3.1e-121 thiN 2.7.6.2 H thiamine pyrophosphokinase
HIMGIKDF_01661 4.2e-26 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HIMGIKDF_01662 5.5e-59 asp S protein conserved in bacteria
HIMGIKDF_01663 2.7e-302 yloV S kinase related to dihydroxyacetone kinase
HIMGIKDF_01664 1.9e-118 sdaAB 4.3.1.17 E L-serine dehydratase
HIMGIKDF_01665 9.3e-156 sdaAA 4.3.1.17 E L-serine dehydratase
HIMGIKDF_01666 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HIMGIKDF_01667 4e-80 fapR 5.3.1.23 K Transcriptional factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism
HIMGIKDF_01668 4.3e-178 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HIMGIKDF_01669 9.1e-170 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMGIKDF_01670 6.1e-129 IQ reductase
HIMGIKDF_01671 2.8e-32 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HIMGIKDF_01672 1.2e-135 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HIMGIKDF_01673 0.0 smc D Required for chromosome condensation and partitioning
HIMGIKDF_01674 8.8e-176 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HIMGIKDF_01675 2.9e-87
HIMGIKDF_01676 1.6e-49 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HIMGIKDF_01677 6e-236 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HIMGIKDF_01678 1.1e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HIMGIKDF_01679 1.2e-36 ylqC S Belongs to the UPF0109 family
HIMGIKDF_01680 1.3e-61 ylqD S YlqD protein
HIMGIKDF_01681 5.3e-95 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HIMGIKDF_01682 9.2e-138 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HIMGIKDF_01683 1.4e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HIMGIKDF_01684 4.2e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HIMGIKDF_01685 4.1e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMGIKDF_01686 8.5e-291 ylqG
HIMGIKDF_01687 3e-44 ylqH S homolog of the cytoplasmic domain of flagellar protein FhlB
HIMGIKDF_01688 3.4e-211 sucC 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
HIMGIKDF_01689 1.1e-167 sucD 6.2.1.5 C Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HIMGIKDF_01690 1.7e-170 dprA LU Rossmann fold nucleotide-binding protein involved in DNA uptake
HIMGIKDF_01691 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HIMGIKDF_01692 7.4e-247 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HIMGIKDF_01693 2.5e-169 xerC L tyrosine recombinase XerC
HIMGIKDF_01694 4.4e-92 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HIMGIKDF_01695 1.5e-250 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HIMGIKDF_01696 9.2e-136 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HIMGIKDF_01697 2.3e-63 flgB N Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body
HIMGIKDF_01698 6.9e-75 flgC N Belongs to the flagella basal body rod proteins family
HIMGIKDF_01699 1.9e-31 fliE N Flagellar hook-basal body
HIMGIKDF_01700 2.4e-255 fliF N The M ring may be actively involved in energy transduction
HIMGIKDF_01701 2e-178 fliG N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMGIKDF_01702 2.5e-106 fliH NU COG1317 Flagellar biosynthesis type III secretory pathway protein
HIMGIKDF_01703 2.5e-242 fliI 3.6.3.14 NU COG1157 Flagellar biosynthesis type III secretory pathway ATPase
HIMGIKDF_01704 1.5e-69 fliJ N Flagellar biosynthesis chaperone
HIMGIKDF_01705 7.7e-37 ylxF S MgtE intracellular N domain
HIMGIKDF_01706 1.2e-221 fliK N Flagellar hook-length control protein
HIMGIKDF_01707 1.7e-72 flgD N Flagellar basal body rod modification protein
HIMGIKDF_01708 8.2e-140 flgG N Flagellar basal body rod
HIMGIKDF_01709 4.6e-49 fliL N Controls the rotational direction of flagella during chemotaxis
HIMGIKDF_01710 1.9e-181 fliM N One of the proteins that forms a switch complex that is proposed to be located at the base of the basal body. This complex interacts with chemotaxis proteins (such as CheY) in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMGIKDF_01711 4.5e-184 fliN N FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HIMGIKDF_01712 1.6e-58 cheB 3.1.1.61, 3.5.1.44 T response regulator
HIMGIKDF_01713 9.3e-97 fliZ N Flagellar biosynthesis protein, FliO
HIMGIKDF_01714 1.6e-109 fliP N Plays a role in the flagellum-specific transport system
HIMGIKDF_01715 2.2e-36 fliQ N Role in flagellar biosynthesis
HIMGIKDF_01716 3.6e-132 fliR N Flagellar biosynthetic protein FliR
HIMGIKDF_01717 1.4e-190 flhB N Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIMGIKDF_01718 0.0 flhA N Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HIMGIKDF_01719 5.2e-201 flhF N Flagellar biosynthesis regulator FlhF
HIMGIKDF_01720 7.5e-158 flhG D Belongs to the ParA family
HIMGIKDF_01721 5.8e-197 cheB 3.1.1.61, 3.5.1.44 NT catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR
HIMGIKDF_01722 0.0 cheA 2.7.13.3 NT COG0643 Chemotaxis protein histidine kinase and related kinases
HIMGIKDF_01723 2.8e-79 cheW NT COG0835 Chemotaxis signal transduction protein
HIMGIKDF_01724 1.3e-111 cheC NT COG1776 Chemotaxis protein CheC, inhibitor of MCP methylation
HIMGIKDF_01725 1.1e-86 cheD 3.5.1.44 NT Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase
HIMGIKDF_01726 5.6e-138 sigD K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_01727 4.3e-78 ylxL
HIMGIKDF_01728 1e-131 rpsB J Belongs to the universal ribosomal protein uS2 family
HIMGIKDF_01729 6.3e-157 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HIMGIKDF_01730 2.7e-126 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HIMGIKDF_01731 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HIMGIKDF_01732 8.3e-145 uppS 2.5.1.31 I Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HIMGIKDF_01733 1.2e-138 cdsA 2.7.7.41 S Belongs to the CDS family
HIMGIKDF_01734 4.6e-216 dxr 1.1.1.267 I Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)
HIMGIKDF_01735 7.7e-233 rasP M zinc metalloprotease
HIMGIKDF_01736 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HIMGIKDF_01737 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HIMGIKDF_01738 3.3e-80 rimP S Required for maturation of 30S ribosomal subunits
HIMGIKDF_01739 1.1e-203 nusA K Participates in both transcription termination and antitermination
HIMGIKDF_01740 3.4e-32 ylxR K nucleic-acid-binding protein implicated in transcription termination
HIMGIKDF_01741 3.1e-47 ylxQ J ribosomal protein
HIMGIKDF_01742 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HIMGIKDF_01743 3e-44 ylxP S protein conserved in bacteria
HIMGIKDF_01744 5e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HIMGIKDF_01745 1.3e-173 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HIMGIKDF_01746 6.1e-182 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HIMGIKDF_01747 6e-42 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HIMGIKDF_01748 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
HIMGIKDF_01749 3.2e-172 ylxY 3.5.1.104 G Sporulation protein, polysaccharide deacetylase
HIMGIKDF_01750 4.4e-233 pepR S Belongs to the peptidase M16 family
HIMGIKDF_01751 2.6e-42 ymxH S YlmC YmxH family
HIMGIKDF_01752 2.9e-162 spoVFA 1.1.1.29, 1.1.1.399, 1.1.1.95 CH Dipicolinate synthase subunit A
HIMGIKDF_01753 4.3e-109 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HIMGIKDF_01754 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMGIKDF_01755 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HIMGIKDF_01756 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIMGIKDF_01757 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMGIKDF_01758 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HIMGIKDF_01759 4.4e-32 S YlzJ-like protein
HIMGIKDF_01760 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIMGIKDF_01761 1.4e-133 ymfC K Transcriptional regulator
HIMGIKDF_01762 3.4e-206 ymfD EGP Major facilitator Superfamily
HIMGIKDF_01763 2.6e-236 ymfF S Peptidase M16
HIMGIKDF_01764 1.4e-242 ymfH S zinc protease
HIMGIKDF_01765 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HIMGIKDF_01766 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HIMGIKDF_01767 2.4e-76 ymfK S Protein of unknown function (DUF3388)
HIMGIKDF_01768 3.1e-53 ymfK S Protein of unknown function (DUF3388)
HIMGIKDF_01769 1.9e-124 ymfM S protein conserved in bacteria
HIMGIKDF_01770 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMGIKDF_01771 1.8e-17 cinA 3.5.1.42 S Belongs to the CinA family
HIMGIKDF_01772 1.2e-49 spoVFB H Together with DpaA, catalyzes the conversion of dihydrodipicolinate to dipicolinate (DPA)
HIMGIKDF_01773 1.4e-192 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HIMGIKDF_01774 5.9e-222 dapG 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HIMGIKDF_01775 1.4e-156 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HIMGIKDF_01776 1.9e-308 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HIMGIKDF_01777 5.3e-133 tepA 3.4.21.92 OU COG0740 Protease subunit of ATP-dependent Clp proteases
HIMGIKDF_01778 4.4e-32 S YlzJ-like protein
HIMGIKDF_01779 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HIMGIKDF_01780 1.4e-133 ymfC K Transcriptional regulator
HIMGIKDF_01781 3.4e-206 ymfD EGP Major facilitator Superfamily
HIMGIKDF_01782 2.6e-236 ymfF S Peptidase M16
HIMGIKDF_01783 1.4e-242 ymfH S zinc protease
HIMGIKDF_01784 9.2e-130 ymfI 1.1.1.100, 1.3.1.28 S Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis
HIMGIKDF_01785 4.8e-41 ymfJ S Protein of unknown function (DUF3243)
HIMGIKDF_01786 2.4e-76 ymfK S Protein of unknown function (DUF3388)
HIMGIKDF_01787 3.1e-53 ymfK S Protein of unknown function (DUF3388)
HIMGIKDF_01788 1.9e-124 ymfM S protein conserved in bacteria
HIMGIKDF_01789 2.5e-101 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HIMGIKDF_01790 1.9e-236 cinA 3.5.1.42 S Belongs to the CinA family
HIMGIKDF_01791 8.1e-188 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HIMGIKDF_01792 1e-215 pbpX V Beta-lactamase
HIMGIKDF_01793 2.1e-224 rny S Endoribonuclease that initiates mRNA decay
HIMGIKDF_01794 1.9e-152 ymdB S protein conserved in bacteria
HIMGIKDF_01795 1.2e-36 spoVS S Stage V sporulation protein S
HIMGIKDF_01796 2.7e-199 tdh 1.1.1.103 C Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate
HIMGIKDF_01797 6.5e-218 kbl 2.3.1.29, 2.3.1.47 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIMGIKDF_01798 2.7e-296 miaB 2.8.4.3 J Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HIMGIKDF_01799 9.2e-69 ymcA 3.6.3.21 S Belongs to the UPF0342 family
HIMGIKDF_01800 2.2e-88 cotE S Spore coat protein
HIMGIKDF_01801 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HIMGIKDF_01802 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HIMGIKDF_01803 2.3e-70 S Regulatory protein YrvL
HIMGIKDF_01805 1.2e-97 ymcC S Membrane
HIMGIKDF_01806 4.4e-109 pksA K Transcriptional regulator
HIMGIKDF_01807 2.5e-129 pksB 3.1.2.6 S Polyketide biosynthesis
HIMGIKDF_01808 2.6e-163 fabD 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMGIKDF_01810 2.4e-186 pksD Q Acyl transferase domain
HIMGIKDF_01811 0.0 fabD 1.13.12.16, 2.3.1.39 I malonyl CoA-acyl carrier protein transacylase
HIMGIKDF_01812 1.4e-37 acpK IQ Phosphopantetheine attachment site
HIMGIKDF_01813 2.7e-238 pksF 2.3.1.179, 2.3.1.41 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HIMGIKDF_01814 1.3e-245 pksG 2.3.3.10 I synthase
HIMGIKDF_01815 2.6e-143 pksH 4.2.1.18 I enoyl-CoA hydratase
HIMGIKDF_01816 2.7e-137 pksI I Belongs to the enoyl-CoA hydratase isomerase family
HIMGIKDF_01817 0.0 rhiB IQ polyketide synthase
HIMGIKDF_01818 0.0 pfaA Q Polyketide synthase of type I
HIMGIKDF_01819 0.0 pfaA 4.1.1.35 GT4 IQ polyketide synthase
HIMGIKDF_01820 0.0 dhbF IQ polyketide synthase
HIMGIKDF_01821 0.0 dhbF IQ polyketide synthase
HIMGIKDF_01822 0.0 pks13 HQ Beta-ketoacyl synthase
HIMGIKDF_01823 2.5e-233 cypA C Cytochrome P450
HIMGIKDF_01824 1.2e-61 ymzB
HIMGIKDF_01825 6.6e-164 ymaE S Metallo-beta-lactamase superfamily
HIMGIKDF_01826 4.6e-252 aprX O Belongs to the peptidase S8 family
HIMGIKDF_01827 2.1e-126 ymaC S Replication protein
HIMGIKDF_01828 5.4e-80 ymaD O redox protein, regulator of disulfide bond formation
HIMGIKDF_01829 4.7e-55 ebrB P COG2076 Membrane transporters of cations and cationic drugs
HIMGIKDF_01830 4.9e-51 ebrA P Small Multidrug Resistance protein
HIMGIKDF_01832 2.1e-46 ymaF S YmaF family
HIMGIKDF_01833 9.3e-175 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HIMGIKDF_01834 1.9e-33 hfq J RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
HIMGIKDF_01835 6.3e-23
HIMGIKDF_01836 4.5e-22 ymzA
HIMGIKDF_01837 1.9e-49 nrdI 1.17.4.1 F Probably involved in ribonucleotide reductase function
HIMGIKDF_01838 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMGIKDF_01839 4.5e-188 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HIMGIKDF_01840 2e-109 ymaB
HIMGIKDF_01841 8e-116 cwlC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMGIKDF_01842 1.7e-176 spoVK O stage V sporulation protein K
HIMGIKDF_01843 5.5e-231 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HIMGIKDF_01844 3.3e-244 ynbB 4.4.1.1 P COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance
HIMGIKDF_01845 1.1e-68 glnR K transcriptional
HIMGIKDF_01846 7e-261 glnA 6.3.1.2 E glutamine synthetase
HIMGIKDF_01847 5e-10
HIMGIKDF_01848 2.5e-32
HIMGIKDF_01849 5.8e-39
HIMGIKDF_01850 6.8e-80 G regulation of fungal-type cell wall biogenesis
HIMGIKDF_01851 4.9e-145 ynaC
HIMGIKDF_01852 2e-99 ynaD J Acetyltransferase (GNAT) domain
HIMGIKDF_01853 1.9e-123 ynaE S Domain of unknown function (DUF3885)
HIMGIKDF_01854 6.4e-60 ynaF
HIMGIKDF_01857 1.1e-83 XK27_05370 5.3.1.24 E phosphoribosylanthranilate isomerase activity
HIMGIKDF_01858 2.7e-255 xynT G MFS/sugar transport protein
HIMGIKDF_01859 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMGIKDF_01860 1e-215 xylR GK ROK family
HIMGIKDF_01861 4e-264 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HIMGIKDF_01862 6e-293 xylB 2.7.1.12, 2.7.1.17, 2.7.1.5 G xylulose kinase
HIMGIKDF_01863 1.4e-113 yokF 3.1.31.1 L RNA catabolic process
HIMGIKDF_01864 3.5e-247 iolT EGP Major facilitator Superfamily
HIMGIKDF_01865 2.7e-219 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HIMGIKDF_01866 6.3e-84 yncE S Protein of unknown function (DUF2691)
HIMGIKDF_01867 4.9e-78 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F Deoxyuridine 5'-triphosphate
HIMGIKDF_01868 5.2e-15
HIMGIKDF_01871 1.2e-165 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMGIKDF_01873 1.3e-134 S Domain of unknown function, YrpD
HIMGIKDF_01876 7.9e-25 tatA U protein secretion
HIMGIKDF_01877 1.8e-71
HIMGIKDF_01878 5.2e-80 yndB S Activator of Hsp90 ATPase homolog 1-like protein
HIMGIKDF_01881 5.7e-286 gerAA EG Spore germination protein
HIMGIKDF_01882 4.5e-197 gerAB U Spore germination
HIMGIKDF_01883 4.2e-220 gerLC S Spore germination protein
HIMGIKDF_01884 7.7e-154 yndG S DoxX-like family
HIMGIKDF_01885 2.6e-117 yndH S Domain of unknown function (DUF4166)
HIMGIKDF_01886 0.0 yndJ S YndJ-like protein
HIMGIKDF_01888 8.6e-139 yndL S Replication protein
HIMGIKDF_01889 5.8e-74 yndM S Protein of unknown function (DUF2512)
HIMGIKDF_01890 2e-79 fosB 2.5.1.18 H Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor
HIMGIKDF_01892 2.6e-109 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HIMGIKDF_01893 3.4e-49 yneA D Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery
HIMGIKDF_01894 9.2e-113 yneB L resolvase
HIMGIKDF_01895 1.3e-32 ynzC S UPF0291 protein
HIMGIKDF_01896 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HIMGIKDF_01897 2.2e-81 yneE S Sporulation inhibitor of replication protein sirA
HIMGIKDF_01898 1.8e-28 yneF S UPF0154 protein
HIMGIKDF_01899 7.5e-14 ynzD S Spo0E like sporulation regulatory protein
HIMGIKDF_01900 7.1e-127 ccdA O cytochrome c biogenesis protein
HIMGIKDF_01901 7.2e-59 cheB 3.1.1.61, 3.5.1.44 T cheY-homologous receiver domain
HIMGIKDF_01902 5.1e-76 yneJ O COG4846 Membrane protein involved in cytochrome C biogenesis
HIMGIKDF_01903 4.2e-74 yneK S Protein of unknown function (DUF2621)
HIMGIKDF_01904 4.1e-65 hspX O Spore coat protein
HIMGIKDF_01905 3.9e-19 sspP S Belongs to the SspP family
HIMGIKDF_01906 2.2e-14 sspO S Belongs to the SspO family
HIMGIKDF_01907 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HIMGIKDF_01908 4.1e-92 yneN CO alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HIMGIKDF_01910 3.1e-08 sspN S Small acid-soluble spore protein N family
HIMGIKDF_01911 3.9e-35 tlp S Belongs to the Tlp family
HIMGIKDF_01912 1.2e-73 yneP S Thioesterase-like superfamily
HIMGIKDF_01913 1.3e-53 yneQ
HIMGIKDF_01914 4.1e-49 yneR S Belongs to the HesB IscA family
HIMGIKDF_01915 5e-94 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HIMGIKDF_01916 6.6e-69 yccU S CoA-binding protein
HIMGIKDF_01917 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMGIKDF_01918 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HIMGIKDF_01919 5.9e-43 ynfC
HIMGIKDF_01920 8.2e-252 agcS E Sodium alanine symporter
HIMGIKDF_01921 2.4e-297 bglC5 3.2.1.4 GH5,GH9 G PFAM glycoside hydrolase family 5
HIMGIKDF_01923 3.7e-251 xynC 3.2.1.136 GH5 M Belongs to the glycosyl hydrolase 30 family
HIMGIKDF_01924 4.4e-299 xynD3 3.2.1.55 CBM6,GH43 G Belongs to the glycosyl hydrolase 43 family
HIMGIKDF_01925 2.4e-80 yngA S membrane
HIMGIKDF_01926 4.1e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMGIKDF_01927 5.5e-104 yngC S membrane-associated protein
HIMGIKDF_01928 1.9e-233 nrnB S phosphohydrolase (DHH superfamily)
HIMGIKDF_01929 6.3e-290 yngE 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIMGIKDF_01930 2.2e-137 yngF 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HIMGIKDF_01931 8e-168 mvaB 4.1.3.4, 6.4.1.4 E Hydroxymethylglutaryl-CoA lyase
HIMGIKDF_01932 6e-32 pycB 2.3.1.12, 6.4.1.1 I Biotin carboxyl carrier protein
HIMGIKDF_01933 3e-251 yngH 6.3.4.14, 6.4.1.2, 6.4.1.3, 6.4.1.4 I Biotin carboxylase
HIMGIKDF_01934 0.0 yngI IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMGIKDF_01935 4.4e-211 yngJ 1.3.8.1, 1.3.99.12 I acyl-CoA dehydrogenase
HIMGIKDF_01936 1.8e-31 S Family of unknown function (DUF5367)
HIMGIKDF_01937 1.3e-306 yngK T Glycosyl hydrolase-like 10
HIMGIKDF_01938 2.8e-64 yngL S Protein of unknown function (DUF1360)
HIMGIKDF_01939 0.0 6.3.2.14 Q amino acid activation for nonribosomal peptide biosynthetic process
HIMGIKDF_01940 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_01941 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_01942 0.0 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_01943 4.3e-275 dacC 3.4.16.4 M D-alanyl-D-alanine carboxypeptidase
HIMGIKDF_01944 6e-193 yoxA 5.1.3.3 G Aldose 1-epimerase
HIMGIKDF_01945 2.3e-246 yoeA V MATE efflux family protein
HIMGIKDF_01946 1.1e-98 yoeB S IseA DL-endopeptidase inhibitor
HIMGIKDF_01948 2.2e-96 L Integrase
HIMGIKDF_01949 3e-34 yoeD G Helix-turn-helix domain
HIMGIKDF_01950 0.0 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HIMGIKDF_01951 2.5e-158 gltR1 K Transcriptional regulator
HIMGIKDF_01952 5e-187 yogA C COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases
HIMGIKDF_01953 2.7e-293 gltD 1.4.1.13, 1.4.1.14 E COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
HIMGIKDF_01954 0.0 gltB 1.4.1.13, 1.4.1.14, 1.4.7.1 E glutamate synthase
HIMGIKDF_01955 7.8e-155 gltC K Transcriptional regulator
HIMGIKDF_01956 4.1e-206 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HIMGIKDF_01957 2.5e-144 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMGIKDF_01958 1.9e-59 rtp K Plays a role in DNA replication and termination (fork arrest mechanism). Two dimers of rtp bind to the two inverted repeat regions (IRI and IRII) present in the termination site. The binding of each dimer is centered on an 8 bp direct repeat
HIMGIKDF_01959 2.2e-123 fabG 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_01960 3e-42 yoxC S Bacterial protein of unknown function (DUF948)
HIMGIKDF_01961 3.1e-144 yoxB
HIMGIKDF_01962 7.5e-97 yoaA 2.3.1.128 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
HIMGIKDF_01963 6.2e-235 yoaB EGP Major facilitator Superfamily
HIMGIKDF_01964 1e-284 yoaC 2.7.1.12, 2.7.1.17, 2.7.1.189, 2.7.1.5 G FGGY family of carbohydrate kinases, C-terminal domain
HIMGIKDF_01965 1.7e-190 yoaD 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMGIKDF_01966 0.0 yoaE C belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMGIKDF_01967 1.9e-33 yoaF
HIMGIKDF_01968 2.2e-08 ywlA S Uncharacterised protein family (UPF0715)
HIMGIKDF_01969 7e-14
HIMGIKDF_01970 1.5e-38 S Protein of unknown function (DUF4025)
HIMGIKDF_01971 1.3e-187 mcpU NT methyl-accepting chemotaxis protein
HIMGIKDF_01972 8.7e-281 hpaB 1.14.14.9 Q COG2368 Aromatic ring hydroxylase
HIMGIKDF_01973 3.8e-133 yoaJ G Endoglucanase C-terminal domain subunit and related proteins
HIMGIKDF_01974 2.3e-111 yoaK S Membrane
HIMGIKDF_01975 2.3e-198 pelB 4.2.2.10, 4.2.2.2 G Amb_all
HIMGIKDF_01976 1.1e-132 yoqW S Belongs to the SOS response-associated peptidase family
HIMGIKDF_01978 3.8e-234 oxdC 4.1.1.2 G Oxalate decarboxylase
HIMGIKDF_01980 1.5e-146 yoaP 3.1.3.18 K YoaP-like
HIMGIKDF_01981 1.2e-66 yoaQ S Evidence 4 Homologs of previously reported genes of
HIMGIKDF_01982 6e-160 yijE EG EamA-like transporter family
HIMGIKDF_01983 3.7e-78 yoaW
HIMGIKDF_01984 1.1e-118 yoaZ 1.11.1.6, 3.5.1.124 S DJ-1/PfpI family
HIMGIKDF_01985 2.3e-170 bla 3.5.2.6 V beta-lactamase
HIMGIKDF_01989 0.0 pps 2.7.9.2 GT phosphoenolpyruvate synthase
HIMGIKDF_01990 1.8e-121 xlnB 3.2.1.8 G Glycosyl hydrolases family 11
HIMGIKDF_01991 1.4e-37 S TM2 domain
HIMGIKDF_01992 5.7e-58 K Helix-turn-helix
HIMGIKDF_01994 1.6e-69 yoaQ S Evidence 4 Homologs of previously reported genes of
HIMGIKDF_01995 6.6e-127 yoqW S Belongs to the SOS response-associated peptidase family
HIMGIKDF_01996 1.8e-178 yobF
HIMGIKDF_02001 1.7e-207 S aspartate phosphatase
HIMGIKDF_02003 1.2e-123 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMGIKDF_02004 1.4e-59 dinB2 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMGIKDF_02005 2.6e-38 S YolD-like protein
HIMGIKDF_02006 1.2e-49
HIMGIKDF_02007 0.0 K Psort location Cytoplasmic, score
HIMGIKDF_02008 2.7e-157 yobJ
HIMGIKDF_02009 3e-86 S SMI1-KNR4 cell-wall
HIMGIKDF_02010 0.0 L A nuclease of the HNH/ENDO VII superfamily with conserved LHH
HIMGIKDF_02011 7.9e-105 yokH G SMI1 / KNR4 family
HIMGIKDF_02012 1.4e-278 iaaM 1.4.3.4 E COG1231 Monoamine oxidase
HIMGIKDF_02013 0.0 yobO M Pectate lyase superfamily protein
HIMGIKDF_02014 9.9e-55 csaA 6.1.1.10, 6.1.1.20, 6.1.1.6 J tRNA-binding protein
HIMGIKDF_02015 1e-136 yobQ K helix_turn_helix, arabinose operon control protein
HIMGIKDF_02016 2.5e-143 yobR 2.3.1.1 J FR47-like protein
HIMGIKDF_02017 3e-99 yobS K Transcriptional regulator
HIMGIKDF_02018 4.2e-132 yobT S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMGIKDF_02019 1.5e-88 yobU K Bacterial transcription activator, effector binding domain
HIMGIKDF_02020 9e-178 yobV K WYL domain
HIMGIKDF_02021 2.5e-95 yobW
HIMGIKDF_02022 1e-51 czrA K transcriptional
HIMGIKDF_02023 4.4e-118 pvaA M COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
HIMGIKDF_02024 1.5e-92 yozB S membrane
HIMGIKDF_02025 2.2e-145
HIMGIKDF_02026 1.9e-94 yocC
HIMGIKDF_02027 6.9e-189 yocD 3.4.17.13 V peptidase S66
HIMGIKDF_02028 4.1e-203 des 1.14.19.23, 1.14.19.45 I fatty acid desaturase
HIMGIKDF_02029 3.2e-198 desK 2.7.13.3 T Histidine kinase
HIMGIKDF_02030 1e-105 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_02031 7.1e-113 yocH CBM50 M COG1388 FOG LysM repeat
HIMGIKDF_02032 0.0 recQ 3.6.4.12 L DNA helicase
HIMGIKDF_02033 7.9e-114 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIMGIKDF_02034 3.3e-83 dksA T general stress protein
HIMGIKDF_02035 6.4e-54 yocL
HIMGIKDF_02036 6.6e-34
HIMGIKDF_02037 1.3e-87 yocM O Belongs to the small heat shock protein (HSP20) family
HIMGIKDF_02038 1.1e-40 yozN
HIMGIKDF_02039 1.9e-36 yocN
HIMGIKDF_02040 1.4e-41 yozO S Bacterial PH domain
HIMGIKDF_02041 2.7e-31 yozC
HIMGIKDF_02042 4e-289 dhaS 1.2.1.3, 1.2.1.39 C Belongs to the aldehyde dehydrogenase family
HIMGIKDF_02043 0.0 sqhC 4.2.1.137, 5.4.99.7 I COG1657 Squalene cyclase
HIMGIKDF_02044 5.4e-166 sodA 1.15.1.1 P Superoxide dismutase
HIMGIKDF_02045 3.4e-231 yocR S Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family
HIMGIKDF_02046 5.1e-168 yocS S -transporter
HIMGIKDF_02047 1.8e-194 sucB 2.3.1.61 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2)
HIMGIKDF_02048 0.0 sucA 1.2.4.2, 4.1.1.71 C The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components 2- oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3)
HIMGIKDF_02049 0.0 yojO P Von Willebrand factor
HIMGIKDF_02050 1.1e-161 yojN S ATPase family associated with various cellular activities (AAA)
HIMGIKDF_02051 1e-110 sodC 1.15.1.1 P Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HIMGIKDF_02052 1.6e-198 sle1 3.5.1.28 CBM50 M COG1388 FOG LysM repeat
HIMGIKDF_02053 1.8e-231 yojK CG UDP-glucoronosyl and UDP-glucosyl transferase
HIMGIKDF_02054 1.2e-109 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HIMGIKDF_02056 4.2e-245 norM V Multidrug efflux pump
HIMGIKDF_02057 8.4e-151 T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMGIKDF_02058 2.1e-125 yojG S deacetylase
HIMGIKDF_02059 2.2e-60 yojF S Protein of unknown function (DUF1806)
HIMGIKDF_02060 1.5e-43
HIMGIKDF_02061 3.5e-163 rarD S -transporter
HIMGIKDF_02062 2.6e-61 yozR S COG0071 Molecular chaperone (small heat shock protein)
HIMGIKDF_02063 3.4e-09
HIMGIKDF_02064 8.2e-209 gntP EG COG2610 H gluconate symporter and related permeases
HIMGIKDF_02065 3.8e-66 yodA S tautomerase
HIMGIKDF_02066 1.7e-57 yodB K transcriptional
HIMGIKDF_02067 4.8e-108 yodC C nitroreductase
HIMGIKDF_02068 3.8e-113 mhqD S Carboxylesterase
HIMGIKDF_02069 5.8e-174 yodE E COG0346 Lactoylglutathione lyase and related lyases
HIMGIKDF_02070 6.2e-28 S Protein of unknown function (DUF3311)
HIMGIKDF_02071 4.2e-270 yodF E Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMGIKDF_02072 1.9e-253 ctpA 3.4.21.102 M Belongs to the peptidase S41A family
HIMGIKDF_02073 1.7e-128 yodH Q Methyltransferase
HIMGIKDF_02074 5.2e-24 yodI
HIMGIKDF_02075 2.5e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
HIMGIKDF_02076 3.2e-127 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HIMGIKDF_02077 5.3e-09
HIMGIKDF_02078 3.6e-54 yodL S YodL-like
HIMGIKDF_02079 5.4e-107 yodM 3.6.1.27 I Acid phosphatase homologues
HIMGIKDF_02080 2.8e-24 yozD S YozD-like protein
HIMGIKDF_02082 1.4e-124 yodN
HIMGIKDF_02083 1.4e-36 yozE S Belongs to the UPF0346 family
HIMGIKDF_02084 2.9e-47 yokU S YokU-like protein, putative antitoxin
HIMGIKDF_02085 1.4e-278 kamA 5.4.3.2 E lysine 2,3-aminomutase
HIMGIKDF_02086 2.5e-155 yodP 2.3.1.264 K Acetyltransferase (GNAT) family
HIMGIKDF_02087 1.4e-258 yodQ 3.5.1.16 E Acetylornithine deacetylase
HIMGIKDF_02088 1.6e-117 scoB 2.8.3.5, 2.8.3.8, 2.8.3.9 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIMGIKDF_02089 8.1e-10 yodS 2.8.3.8, 2.8.3.9 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIMGIKDF_02090 1.6e-249 yodT H Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HIMGIKDF_02093 2.9e-145 yiiD K acetyltransferase
HIMGIKDF_02094 1e-256 cgeD M maturation of the outermost layer of the spore
HIMGIKDF_02095 3.5e-38 cgeC
HIMGIKDF_02096 2.6e-65 cgeA
HIMGIKDF_02097 3.3e-188 cgeB S Spore maturation protein
HIMGIKDF_02098 3.6e-213 phy 3.1.3.8 I Myo-inositol-hexaphosphate 3-phosphohydrolase
HIMGIKDF_02099 5.6e-125 4.2.1.115 GM Polysaccharide biosynthesis protein
HIMGIKDF_02100 1.4e-80 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HIMGIKDF_02101 7e-103 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HIMGIKDF_02102 1.6e-70 ypoP K transcriptional
HIMGIKDF_02103 2.6e-223 mepA V MATE efflux family protein
HIMGIKDF_02104 5.5e-29 ypmT S Uncharacterized ympT
HIMGIKDF_02105 5e-99 ypmS S protein conserved in bacteria
HIMGIKDF_02106 1.3e-137 ypmR E GDSL-like Lipase/Acylhydrolase
HIMGIKDF_02107 3.2e-109 ypmQ S protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems
HIMGIKDF_02108 3.1e-40 ypmP S Protein of unknown function (DUF2535)
HIMGIKDF_02109 4.4e-244 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HIMGIKDF_02110 1.6e-185 pspF K Transcriptional regulator
HIMGIKDF_02111 4.2e-110 hlyIII S protein, Hemolysin III
HIMGIKDF_02112 7.4e-112 ypkP 2.3.1.51 I Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family
HIMGIKDF_02113 7.9e-96 folA 1.1.1.262, 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HIMGIKDF_02114 4.3e-157 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HIMGIKDF_02115 3.3e-92 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HIMGIKDF_02116 7.8e-114 ypjP S YpjP-like protein
HIMGIKDF_02117 1.3e-145 ypiP 2.1.1.242 AJ Putative SAM-dependent methyltransferase
HIMGIKDF_02118 1.7e-75 yphP S Belongs to the UPF0403 family
HIMGIKDF_02119 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
HIMGIKDF_02120 1.8e-156 ypgR C COG0694 Thioredoxin-like proteins and domains
HIMGIKDF_02121 3.1e-110 ypgQ S phosphohydrolase
HIMGIKDF_02122 2.3e-89 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HIMGIKDF_02123 7.3e-177 metAA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HIMGIKDF_02124 2e-216 ugtP 2.4.1.315 GT28 M Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer up to three glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O-(beta-D-glucopyranosyl)-1,2-diacyl- sn-glycerol), beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl- beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta- triglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1- 6)-D- glucopyranosyl-beta-(1- 6)-D-glucopyranosyl)-1,2-diacyl-sn- glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA)
HIMGIKDF_02125 7.9e-31 cspD K Cold-shock protein
HIMGIKDF_02126 3.8e-16 degR
HIMGIKDF_02127 8.1e-31 S Protein of unknown function (DUF2564)
HIMGIKDF_02128 2.6e-27 ypeQ S Zinc-finger
HIMGIKDF_02129 8.9e-127 ypeP 3.1.26.4 L COG0328 Ribonuclease HI
HIMGIKDF_02130 5.4e-107 ypdP S Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
HIMGIKDF_02131 8.5e-69 rnhA 3.1.26.4 L Ribonuclease
HIMGIKDF_02133 1.5e-166 polA 2.7.7.7 L 5'3' exonuclease
HIMGIKDF_02134 2e-07
HIMGIKDF_02135 1e-38 ypbS S Protein of unknown function (DUF2533)
HIMGIKDF_02136 0.0 ypbR S Dynamin family
HIMGIKDF_02137 5.1e-87 ypbQ S protein conserved in bacteria
HIMGIKDF_02138 4.4e-208 bcsA Q Naringenin-chalcone synthase
HIMGIKDF_02139 1.6e-228 pbuX F xanthine
HIMGIKDF_02140 8.8e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HIMGIKDF_02141 4.2e-294 ypwA 3.4.17.19 E Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
HIMGIKDF_02142 5e-171 kdgT P The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system
HIMGIKDF_02143 7e-104 eda 2.7.1.45, 4.1.2.14, 4.1.3.42 G 2-dehydro-3-deoxy-phosphogluconate aldolase
HIMGIKDF_02144 2.9e-187 kdgK 2.7.1.45 G COG0524 Sugar kinases, ribokinase family
HIMGIKDF_02145 3.9e-187 ptxS K transcriptional
HIMGIKDF_02146 1.7e-159 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HIMGIKDF_02147 7.1e-133 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_02148 0.0 ypvA 3.6.4.12 KL COG1199 Rad3-related DNA helicases
HIMGIKDF_02150 5.4e-225 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HIMGIKDF_02151 2.8e-45 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HIMGIKDF_02152 3.3e-92 ypsA S Belongs to the UPF0398 family
HIMGIKDF_02153 1.3e-237 yprB L RNase_H superfamily
HIMGIKDF_02154 0.0 yprA L COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster
HIMGIKDF_02155 1.9e-81 ypqE 2.7.1.199 G COG2190 Phosphotransferase system IIA components
HIMGIKDF_02156 8.6e-72 hspX O Belongs to the small heat shock protein (HSP20) family
HIMGIKDF_02157 1.2e-48 yppG S YppG-like protein
HIMGIKDF_02159 2e-11 yppE S Bacterial domain of unknown function (DUF1798)
HIMGIKDF_02162 2.6e-188 yppC S Protein of unknown function (DUF2515)
HIMGIKDF_02163 1.2e-114 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HIMGIKDF_02164 0.0 ponA 2.4.1.129, 2.7.7.7, 3.4.16.4 GT51 M penicillin-binding protein
HIMGIKDF_02165 4.7e-93 ypoC
HIMGIKDF_02166 2.2e-122 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HIMGIKDF_02167 5.7e-129 dnaD L DNA replication protein DnaD
HIMGIKDF_02168 5.8e-252 asnS 6.1.1.22 J asparaginyl-tRNA
HIMGIKDF_02169 1.5e-222 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HIMGIKDF_02170 3.4e-80 ypmB S protein conserved in bacteria
HIMGIKDF_02171 6.7e-23 ypmA S Protein of unknown function (DUF4264)
HIMGIKDF_02172 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HIMGIKDF_02173 3.5e-64 panD 4.1.1.11 H Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HIMGIKDF_02174 1.2e-157 panC 2.7.4.25, 6.3.2.1 H Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HIMGIKDF_02175 1.4e-150 panB 2.1.2.11 H Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
HIMGIKDF_02176 8.7e-184 birA 6.3.4.15 K Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HIMGIKDF_02177 4.4e-222 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HIMGIKDF_02178 3.7e-210 bshA GT4 M N-acetyl-alpha-D-glucosaminyl L-malate synthase
HIMGIKDF_02179 6.9e-130 bshB1 S proteins, LmbE homologs
HIMGIKDF_02180 6.5e-72 mgsA 2.7.1.24, 4.2.3.3 G methylglyoxal synthase
HIMGIKDF_02181 6.3e-148 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
HIMGIKDF_02182 3.1e-56 ypjD 2.5.1.19 S Nucleotide pyrophosphohydrolase
HIMGIKDF_02183 8.1e-157 ypjC S Uncharacterized protein conserved in bacteria (DUF2179)
HIMGIKDF_02184 6.1e-143 ypjB S sporulation protein
HIMGIKDF_02185 4.4e-98 ypjA S membrane
HIMGIKDF_02186 1.5e-146 qcrC C Menaquinol-cytochrome c reductase cytochrome b c subunit
HIMGIKDF_02187 5.2e-127 petB C COG1290 Cytochrome b subunit of the bc complex
HIMGIKDF_02188 9.3e-97 qcrA C Menaquinol-cytochrome c reductase
HIMGIKDF_02189 8.5e-78 ypiF S Protein of unknown function (DUF2487)
HIMGIKDF_02190 2.8e-99 ypiB S Belongs to the UPF0302 family
HIMGIKDF_02191 4.1e-234 S COG0457 FOG TPR repeat
HIMGIKDF_02192 8.9e-237 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
HIMGIKDF_02193 1.2e-208 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
HIMGIKDF_02194 2.9e-204 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HIMGIKDF_02195 5.5e-144 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
HIMGIKDF_02196 4e-231 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
HIMGIKDF_02197 6.5e-119 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E Belongs to the TrpF family
HIMGIKDF_02198 2.6e-111 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
HIMGIKDF_02199 1.2e-180 trpD 2.4.2.18, 4.1.3.27 E Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HIMGIKDF_02200 7.1e-281 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HIMGIKDF_02201 1.9e-62 aroH 2.7.4.25, 5.4.99.5 E Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis
HIMGIKDF_02202 7.4e-200 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HIMGIKDF_02203 7.2e-217 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HIMGIKDF_02204 5.7e-138 cheR 2.1.1.80 NT COG1352 Methylase of chemotaxis methyl-accepting proteins
HIMGIKDF_02205 9.1e-80 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
HIMGIKDF_02206 1.4e-192 hepT 2.5.1.30, 2.5.1.83, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMGIKDF_02207 4e-130 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HIMGIKDF_02208 6.9e-136 hepS 2.5.1.30 H Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1
HIMGIKDF_02209 3e-34 mtrB K Required for transcription attenuation control in the Trp operon. This trans-acting factor seems to recognize a 10 bases nucleotide sequence in the Trp leader transcript causing transcription termination. Binds the leader RNA only in presence of L-tryptophan
HIMGIKDF_02210 7.1e-101 folE 3.5.4.16 H GTP cyclohydrolase
HIMGIKDF_02211 4.7e-42 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HIMGIKDF_02212 3.7e-279 spoIVA S ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HIMGIKDF_02213 5.4e-138 yphF
HIMGIKDF_02214 1.6e-18 yphE S Protein of unknown function (DUF2768)
HIMGIKDF_02215 2.3e-190 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HIMGIKDF_02216 3.9e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HIMGIKDF_02217 1.6e-28 ypzH
HIMGIKDF_02218 2.5e-161 seaA S YIEGIA protein
HIMGIKDF_02219 1.3e-102 yphA
HIMGIKDF_02220 1e-07 S YpzI-like protein
HIMGIKDF_02221 4.1e-187 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HIMGIKDF_02222 4.3e-206 rpsA 1.17.7.4 J Ribosomal protein S1
HIMGIKDF_02223 1.9e-113 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HIMGIKDF_02224 1.8e-23 S Family of unknown function (DUF5359)
HIMGIKDF_02225 9.2e-113 ypfA M Flagellar protein YcgR
HIMGIKDF_02226 6.5e-254 hemX 2.1.1.107, 4.2.1.75 H sporulation protein
HIMGIKDF_02227 4.7e-155 sleB 3.5.1.28 M Spore cortex-lytic enzyme
HIMGIKDF_02228 1e-119 prsW S Involved in the degradation of specific anti-sigma factors
HIMGIKDF_02229 1.6e-174 ypdA 1.18.1.2, 1.19.1.1, 1.8.1.9 O COG0492 Thioredoxin reductase
HIMGIKDF_02230 7.3e-247 gudB 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMGIKDF_02231 2.4e-104 mecB NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC
HIMGIKDF_02232 1.8e-147 ypbG S Calcineurin-like phosphoesterase superfamily domain
HIMGIKDF_02233 2.8e-81 ypbF S Protein of unknown function (DUF2663)
HIMGIKDF_02234 4.6e-81 ypbE M Lysin motif
HIMGIKDF_02235 2.2e-100 ypbD S metal-dependent membrane protease
HIMGIKDF_02236 3.2e-286 recQ 3.6.4.12 L DNA helicase
HIMGIKDF_02237 3.8e-201 ypbB 5.1.3.1 S protein conserved in bacteria
HIMGIKDF_02238 4.7e-41 fer C Ferredoxin
HIMGIKDF_02239 5.8e-87 fmnP U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HIMGIKDF_02240 1.5e-294 serA 1.1.1.399, 1.1.1.95 E Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMGIKDF_02241 9e-136 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
HIMGIKDF_02242 6.8e-201 rsiX
HIMGIKDF_02243 2.6e-103 sigX K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_02244 0.0 resE 2.7.13.3 T Histidine kinase
HIMGIKDF_02245 2.3e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_02246 3.9e-215 ccsA O 'COG0755 ABC-type transport system involved in cytochrome c biogenesis, permease component'
HIMGIKDF_02247 0.0 ccs1 O COG1333 ResB protein required for cytochrome c biosynthesis
HIMGIKDF_02248 1.3e-99 resA CO Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c
HIMGIKDF_02249 6.9e-133 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIMGIKDF_02250 1.9e-87 spmB S Spore maturation protein
HIMGIKDF_02251 3.5e-103 spmA S Spore maturation protein
HIMGIKDF_02252 1.2e-213 dacB 3.4.16.4 M Belongs to the peptidase S11 family
HIMGIKDF_02253 4e-98 ypuI S Protein of unknown function (DUF3907)
HIMGIKDF_02254 1.9e-104 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HIMGIKDF_02255 4.5e-130 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HIMGIKDF_02256 4.5e-94 ypuF S Domain of unknown function (DUF309)
HIMGIKDF_02257 4.5e-64 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_02258 3.9e-81 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HIMGIKDF_02259 9.8e-230 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HIMGIKDF_02260 1.5e-115 ribE 2.5.1.9 H Riboflavin synthase
HIMGIKDF_02261 1.3e-204 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HIMGIKDF_02262 6e-55 ypuD
HIMGIKDF_02263 5.2e-101 sipT 3.4.21.89 U Belongs to the peptidase S26 family
HIMGIKDF_02264 2.3e-33 yhcC S nucleic-acid-binding protein containing a Zn-ribbon domain
HIMGIKDF_02265 1.5e-17 S SNARE associated Golgi protein
HIMGIKDF_02268 8e-81 ppiB 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HIMGIKDF_02269 1.3e-149 ypuA S Secreted protein
HIMGIKDF_02270 5.2e-256 lysA 4.1.1.19, 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
HIMGIKDF_02271 1.4e-273 spoVAF EG Stage V sporulation protein AF
HIMGIKDF_02272 1.4e-110 spoVAEA S stage V sporulation protein
HIMGIKDF_02273 2.2e-57 spoVAEB S stage V sporulation protein
HIMGIKDF_02274 9e-192 spoVAD I Stage V sporulation protein AD
HIMGIKDF_02275 2.3e-78 spoVAC S stage V sporulation protein AC
HIMGIKDF_02276 1e-67 spoVAB S Stage V sporulation protein AB
HIMGIKDF_02277 7.4e-112 spoVAA S Stage V sporulation protein AA
HIMGIKDF_02278 2.4e-136 sigF K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_02279 1.8e-75 spoIIAB 2.7.11.1 F Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition
HIMGIKDF_02280 3.9e-57 spoIIAA T Belongs to the anti-sigma-factor antagonist family
HIMGIKDF_02281 2.8e-213 dacF 3.4.16.4 M Belongs to the peptidase S11 family
HIMGIKDF_02282 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HIMGIKDF_02283 1.2e-232 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HIMGIKDF_02284 2.6e-166 xerD L recombinase XerD
HIMGIKDF_02285 3.7e-37 S Protein of unknown function (DUF4227)
HIMGIKDF_02286 2.4e-80 fur P Belongs to the Fur family
HIMGIKDF_02287 2.3e-108 spoIIM S Required for complete septum migration and engulfment of the forespore compartment during sporulation. Required for stabilizing and recruiting of SpoIIP to the septal membrane
HIMGIKDF_02288 2e-32 yqkK
HIMGIKDF_02289 5.5e-242 mleA 1.1.1.38 C malic enzyme
HIMGIKDF_02290 3.1e-235 mleN C Na H antiporter
HIMGIKDF_02291 2.9e-268 aspA 4.2.1.2, 4.3.1.1 E Aspartate ammonia-lyase
HIMGIKDF_02292 3.6e-185 ansA 3.5.1.1 EJ L-asparaginase
HIMGIKDF_02293 4.5e-58 ansR K Transcriptional regulator
HIMGIKDF_02294 3e-223 yqxK 3.6.4.12 L DNA helicase
HIMGIKDF_02295 1.2e-92 nudF 3.6.1.13 L Belongs to the Nudix hydrolase family
HIMGIKDF_02297 4.4e-169 yqkF C oxidoreductases (related to aryl-alcohol dehydrogenases)
HIMGIKDF_02298 4e-14 yqkE S Protein of unknown function (DUF3886)
HIMGIKDF_02299 2.4e-175 yqkD S COG1073 Hydrolases of the alpha beta superfamily
HIMGIKDF_02300 9.4e-39 yqkC S Protein of unknown function (DUF2552)
HIMGIKDF_02301 2.8e-54 yqkB S Belongs to the HesB IscA family
HIMGIKDF_02302 4.7e-196 yqkA K GrpB protein
HIMGIKDF_02303 8e-60 yqjZ 2.3.1.128, 2.5.1.18 S enzyme involved in biosynthesis of extracellular polysaccharides
HIMGIKDF_02304 3.6e-87 yqjY K acetyltransferase
HIMGIKDF_02305 2.2e-49 S YolD-like protein
HIMGIKDF_02306 3.1e-239 polYB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMGIKDF_02308 5.2e-226 yqjV G Major Facilitator Superfamily
HIMGIKDF_02310 7.2e-73 yqjT 3.1.26.4 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_02311 2.4e-178 coaA 2.7.1.33 F Pantothenic acid kinase
HIMGIKDF_02312 2.4e-264 dsdA 4.3.1.18 E Belongs to the serine threonine dehydratase family. DsdA subfamily
HIMGIKDF_02313 3.5e-143 yqjQ S Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_02314 3.4e-180 yqjP S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMGIKDF_02315 8.6e-148 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMGIKDF_02316 0.0 rocB E arginine degradation protein
HIMGIKDF_02317 1.4e-192 namA 1.6.99.1 C Catalyzes the reduction of the double bond of an array of alpha,beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes
HIMGIKDF_02318 9.6e-146 yqjL S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
HIMGIKDF_02319 2.9e-173 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HIMGIKDF_02320 1.6e-290 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HIMGIKDF_02321 6.9e-267 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIMGIKDF_02322 7.3e-236 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HIMGIKDF_02323 4.5e-24 yqzJ
HIMGIKDF_02324 5.7e-144 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMGIKDF_02325 3.6e-142 yqjF S Uncharacterized conserved protein (COG2071)
HIMGIKDF_02326 1.6e-202 yqjE 3.4.11.4 E COG2195 Di- and tripeptidases
HIMGIKDF_02327 4.4e-291 mmdA 2.1.3.15, 6.4.1.3 I COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
HIMGIKDF_02328 2.2e-75 mce 4.4.1.5, 5.1.99.1, 5.4.99.2 E COG0346 Lactoylglutathione lyase and related lyases
HIMGIKDF_02330 1.4e-98 yqjB S protein conserved in bacteria
HIMGIKDF_02331 1.1e-175 yqjA S Putative aromatic acid exporter C-terminal domain
HIMGIKDF_02332 2e-129 artM 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMGIKDF_02333 6.2e-109 artQ E COG0765 ABC-type amino acid transport system, permease component
HIMGIKDF_02334 6.3e-137 artP ET Belongs to the bacterial solute-binding protein 3 family
HIMGIKDF_02335 9.3e-77 yqiW S Belongs to the UPF0403 family
HIMGIKDF_02336 8.8e-167 yegS 2.7.1.107 I COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
HIMGIKDF_02337 7.9e-208 norA EGP Major facilitator Superfamily
HIMGIKDF_02338 2.6e-152 bmrR K helix_turn_helix, mercury resistance
HIMGIKDF_02339 3.5e-233 bfmBB 2.3.1.168, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HIMGIKDF_02340 1.8e-184 bfmBAB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
HIMGIKDF_02341 1.9e-186 bfmBAA 1.2.4.4 C COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit
HIMGIKDF_02342 3.4e-269 lpdA 1.8.1.4 C COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
HIMGIKDF_02343 1.2e-202 buk 2.7.2.7 C Belongs to the acetokinase family
HIMGIKDF_02344 2.2e-207 ldh 1.4.1.9 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMGIKDF_02345 7.1e-156 pta 2.3.1.19, 2.3.1.8 C phosphate butyryltransferase
HIMGIKDF_02346 0.0 bkdR 2.7.13.3 KT Transcriptional regulator
HIMGIKDF_02347 4e-34 yqzF S Protein of unknown function (DUF2627)
HIMGIKDF_02348 7.1e-164 prpB 4.1.3.30 G Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
HIMGIKDF_02349 5.7e-277 prpD 4.2.1.79 S 2-methylcitrate dehydratase
HIMGIKDF_02350 8.1e-210 prpC 2.3.3.1, 2.3.3.5 C Belongs to the citrate synthase family
HIMGIKDF_02351 1.8e-212 mmgC I acyl-CoA dehydrogenase
HIMGIKDF_02352 4.7e-157 hbdA 1.1.1.157 I Dehydrogenase
HIMGIKDF_02353 1.2e-219 mmgA 2.3.1.9 I Belongs to the thiolase family
HIMGIKDF_02354 1.8e-133 yqiK 3.1.4.46 C glycerophosphoryl diester phosphodiesterase
HIMGIKDF_02355 5.4e-107 amiC 3.5.1.28 M Cell wall hydrolase autolysin
HIMGIKDF_02356 5.9e-27
HIMGIKDF_02357 1.3e-215 yqiG C COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family
HIMGIKDF_02359 3.2e-144 KT May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process
HIMGIKDF_02360 1.2e-238 rseP 3.4.21.116 M Stage IV sporulation protein B
HIMGIKDF_02361 0.0 recN L May be involved in recombinational repair of damaged DNA
HIMGIKDF_02362 1.7e-78 argR K Regulates arginine biosynthesis genes
HIMGIKDF_02363 6.6e-156 rrmJ 2.1.1.226, 2.1.1.227 J rRNA methylase
HIMGIKDF_02364 0.0 dxs 2.2.1.7 H Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HIMGIKDF_02365 7.7e-163 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HIMGIKDF_02366 5.8e-39 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMGIKDF_02367 2.2e-246 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HIMGIKDF_02368 1e-156 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HIMGIKDF_02369 1.9e-65 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HIMGIKDF_02370 2.1e-67 yqhY S protein conserved in bacteria
HIMGIKDF_02371 1.5e-255 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
HIMGIKDF_02372 1.5e-64 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HIMGIKDF_02373 9.9e-91 spoIIIAH S SpoIIIAH-like protein
HIMGIKDF_02374 6.9e-103 spoIIIAG S stage III sporulation protein AG
HIMGIKDF_02375 3.1e-102 spoIIIAF S Stage III sporulation protein AF (Spore_III_AF)
HIMGIKDF_02376 1.3e-197 spoIIIAE S stage III sporulation protein AE
HIMGIKDF_02377 2.3e-58 spoIIIAD S Stage III sporulation protein AD
HIMGIKDF_02378 7.6e-29 spoIIIAC S stage III sporulation protein AC
HIMGIKDF_02379 2.9e-85 spoIIIAB S Stage III sporulation protein
HIMGIKDF_02380 1.2e-171 spoIIIAA S stage III sporulation protein AA
HIMGIKDF_02381 7.9e-37 yqhV S Protein of unknown function (DUF2619)
HIMGIKDF_02382 5.4e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HIMGIKDF_02383 8.9e-174 yqhT 3.4.11.9, 3.4.13.9 E COG0006 Xaa-Pro aminopeptidase
HIMGIKDF_02384 1.5e-77 aroQ 4.2.1.10 E Catalyzes a trans-dehydration via an enolate intermediate
HIMGIKDF_02385 2.3e-93 yqhR S Conserved membrane protein YqhR
HIMGIKDF_02386 9.4e-175 yqhQ S Protein of unknown function (DUF1385)
HIMGIKDF_02387 2.2e-61 yqhP
HIMGIKDF_02388 8.1e-165 yqhO S esterase of the alpha-beta hydrolase superfamily
HIMGIKDF_02389 9.4e-74 mntR K Involved in manganese homeostasis. Might activate the transcription of the mntABCD operon
HIMGIKDF_02390 5.2e-161 lipM 6.3.1.20 H Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation
HIMGIKDF_02391 2.3e-63 yqhL P COG0607 Rhodanese-related sulfurtransferase
HIMGIKDF_02392 2.8e-287 gcvPB 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIMGIKDF_02393 3.4e-255 gcvPA 1.4.4.2 E The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HIMGIKDF_02394 9.6e-208 gcvT 1.4.4.2, 2.1.2.10 E The glycine cleavage system catalyzes the degradation of glycine
HIMGIKDF_02395 0.0 yqhH L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIMGIKDF_02396 2.5e-152 yqhG S Bacterial protein YqhG of unknown function
HIMGIKDF_02397 1.2e-24 sinI S Anti-repressor SinI
HIMGIKDF_02398 1e-54 sinR K transcriptional
HIMGIKDF_02399 2.3e-142 tasA S Cell division protein FtsN
HIMGIKDF_02400 6.7e-59 sipW 3.4.21.89 U Signal peptidase
HIMGIKDF_02401 2.1e-116 yqxM
HIMGIKDF_02402 7.3e-54 yqzG S Protein of unknown function (DUF3889)
HIMGIKDF_02403 1.4e-26 yqzE S YqzE-like protein
HIMGIKDF_02404 3.7e-42 S ComG operon protein 7
HIMGIKDF_02405 5.5e-49 comGF U Putative Competence protein ComGF
HIMGIKDF_02406 1.1e-59 comGE
HIMGIKDF_02407 4.4e-71 gspH NU protein transport across the cell outer membrane
HIMGIKDF_02408 1.4e-47 comGC U Required for transformation and DNA binding
HIMGIKDF_02409 1.6e-175 comGB NU COG1459 Type II secretory pathway, component PulF
HIMGIKDF_02410 3.9e-201 comGA NU COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HIMGIKDF_02412 7.2e-175 corA P Mg2 transporter protein
HIMGIKDF_02413 5.2e-240 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HIMGIKDF_02414 1.7e-151 yqhA T COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)
HIMGIKDF_02416 2.7e-64 yqgZ 1.20.4.1 P Belongs to the ArsC family
HIMGIKDF_02417 1.8e-37 yqgY S Protein of unknown function (DUF2626)
HIMGIKDF_02418 1.9e-123 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMGIKDF_02419 8.9e-23 yqgW S Protein of unknown function (DUF2759)
HIMGIKDF_02420 6.9e-50 yqgV S Thiamine-binding protein
HIMGIKDF_02421 2.7e-199 yqgU
HIMGIKDF_02422 1.4e-222 yqgT 3.4.19.11 E Gamma-D-glutamyl-L-diamino acid endopeptidase
HIMGIKDF_02423 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMGIKDF_02424 5.2e-181 glcK 2.7.1.2 G Glucokinase
HIMGIKDF_02425 3.1e-33 yqgQ S Protein conserved in bacteria
HIMGIKDF_02426 1.4e-268 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
HIMGIKDF_02427 2.5e-09 yqgO
HIMGIKDF_02428 2.7e-105 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HIMGIKDF_02429 9.4e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HIMGIKDF_02430 3.2e-203 yqgM 2.4.1.11, 2.4.1.18 GH57,GT4 M Glycosyl transferases group 1
HIMGIKDF_02432 9.2e-51 yqzD
HIMGIKDF_02433 1.9e-75 yqzC S YceG-like family
HIMGIKDF_02434 9.8e-146 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMGIKDF_02435 6.4e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HIMGIKDF_02436 4.4e-158 pstA P Phosphate transport system permease
HIMGIKDF_02437 1.3e-160 pstC P probably responsible for the translocation of the substrate across the membrane
HIMGIKDF_02438 5.3e-151 pstS P Phosphate
HIMGIKDF_02439 0.0 pbpA 3.4.16.4 M penicillin-binding protein
HIMGIKDF_02440 2.5e-231 yqgE EGP Major facilitator superfamily
HIMGIKDF_02441 6.3e-116 sodA 1.15.1.1 P radicals which are normally produced within the cells and which are toxic to biological systems
HIMGIKDF_02442 4e-73 yqgC S protein conserved in bacteria
HIMGIKDF_02443 8.5e-134 yqgB S Protein of unknown function (DUF1189)
HIMGIKDF_02444 2.2e-75 yqgA
HIMGIKDF_02445 5.2e-47 yqfZ M LysM domain
HIMGIKDF_02446 2.8e-202 ispG 1.17.7.1, 1.17.7.3 I Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HIMGIKDF_02447 4.3e-62 yqfX S membrane
HIMGIKDF_02448 1.2e-108 yqfW S Belongs to the 5'(3')-deoxyribonucleotidase family
HIMGIKDF_02449 1.9e-77 zur P Belongs to the Fur family
HIMGIKDF_02450 1.6e-157 yqfU S Uncharacterized protein conserved in bacteria (DUF2179)
HIMGIKDF_02451 2.1e-36 yqfT S Protein of unknown function (DUF2624)
HIMGIKDF_02452 8.8e-167 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HIMGIKDF_02453 1.7e-243 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HIMGIKDF_02454 2.9e-14 yqfQ S YqfQ-like protein
HIMGIKDF_02455 2.6e-177 ispH 1.17.7.4, 2.7.4.25 IM Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HIMGIKDF_02456 5.1e-212 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HIMGIKDF_02457 6.1e-117 trmK 2.1.1.217 S SAM-dependent methyltransferase
HIMGIKDF_02458 1.6e-61 cccA C COG2010 Cytochrome c, mono- and diheme variants
HIMGIKDF_02459 1.2e-200 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HIMGIKDF_02460 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HIMGIKDF_02461 4.5e-88 yaiI S Belongs to the UPF0178 family
HIMGIKDF_02462 5.8e-149 yqfL 2.7.11.33, 2.7.4.28 S Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HIMGIKDF_02463 4.5e-112 ccpN K CBS domain
HIMGIKDF_02464 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HIMGIKDF_02465 3.3e-174 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HIMGIKDF_02466 4.8e-145 recO L Involved in DNA repair and RecF pathway recombination
HIMGIKDF_02467 8.4e-19 S YqzL-like protein
HIMGIKDF_02468 3.1e-167 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HIMGIKDF_02469 7.1e-71 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HIMGIKDF_02470 1.6e-61 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HIMGIKDF_02471 5.1e-81 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HIMGIKDF_02472 0.0 yqfF S membrane-associated HD superfamily hydrolase
HIMGIKDF_02474 1.1e-175 phoH T Phosphate starvation-inducible protein PhoH
HIMGIKDF_02475 1.5e-185 yqfD 3.1.3.102, 3.1.3.104 S Stage IV sporulation
HIMGIKDF_02476 2.7e-45 yqfC S sporulation protein YqfC
HIMGIKDF_02477 6e-25 yqfB
HIMGIKDF_02478 4.3e-122 yqfA S UPF0365 protein
HIMGIKDF_02479 5.4e-229 yqeZ O COG1030 Membrane-bound serine protease (ClpP class)
HIMGIKDF_02480 2.5e-61 yqeY S Yqey-like protein
HIMGIKDF_02481 1.2e-19 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HIMGIKDF_02482 1.6e-158 yqeW P COG1283 Na phosphate symporter
HIMGIKDF_02483 2.1e-260 yqeV 2.8.4.5 J ribosomal protein S12 methylthiotransferase
HIMGIKDF_02484 1.4e-141 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HIMGIKDF_02485 5.4e-175 prmA J Methylates ribosomal protein L11
HIMGIKDF_02486 4.2e-182 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HIMGIKDF_02487 0.0 dnaK O Heat shock 70 kDa protein
HIMGIKDF_02488 3.8e-75 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HIMGIKDF_02489 4.7e-188 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HIMGIKDF_02490 4.8e-218 hemN H Involved in the biosynthesis of porphyrin-containing compound
HIMGIKDF_02491 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HIMGIKDF_02492 1e-54 yqxA S Protein of unknown function (DUF3679)
HIMGIKDF_02493 6.9e-223 spoIIP M stage II sporulation protein P
HIMGIKDF_02494 1.3e-204 gpr 3.4.24.78 C Initiates the rapid degradation of small, acid-soluble proteins during spore germination
HIMGIKDF_02495 9.7e-37 rpsT J Binds directly to 16S ribosomal RNA
HIMGIKDF_02496 1.1e-189 holA 2.7.7.7 L DNA polymerase III delta subunit
HIMGIKDF_02497 4.1e-15 S YqzM-like protein
HIMGIKDF_02498 0.0 comEC S Competence protein ComEC
HIMGIKDF_02499 2.1e-105 comEB 3.5.4.12 F ComE operon protein 2
HIMGIKDF_02500 3e-105 wza L COG1555 DNA uptake protein and related DNA-binding proteins
HIMGIKDF_02501 8.4e-148 comER E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HIMGIKDF_02502 2.9e-139 yqeM Q Methyltransferase
HIMGIKDF_02503 6.9e-62 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HIMGIKDF_02504 7.4e-103 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
HIMGIKDF_02505 2.7e-108 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HIMGIKDF_02506 2.1e-45 yhbY J RNA-binding protein containing KH domain, possibly ribosomal protein
HIMGIKDF_02507 2.7e-157 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HIMGIKDF_02508 9.1e-214 yqeH S In Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
HIMGIKDF_02509 5.3e-95 yqeG S hydrolase of the HAD superfamily
HIMGIKDF_02511 6.2e-142 yqeF E GDSL-like Lipase/Acylhydrolase
HIMGIKDF_02512 2.1e-137 xlyA 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMGIKDF_02513 4.7e-106 yqeD S SNARE associated Golgi protein
HIMGIKDF_02514 1.2e-171 gnd 1.1.1.343, 1.1.1.44 G 6-phosphogluconate dehydrogenase
HIMGIKDF_02515 2.3e-133 yqeB
HIMGIKDF_02516 1.1e-74 nucB M Deoxyribonuclease NucA/NucB
HIMGIKDF_02517 3.3e-56 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_02518 1.4e-281 cisA2 L Recombinase
HIMGIKDF_02519 1.8e-77 arsC 1.20.4.1 T Catalyzes the reduction of arsenate As(V) to arsenite As(III)
HIMGIKDF_02520 6e-183 arsB 1.20.4.1 P Arsenic resistance protein
HIMGIKDF_02521 2.8e-73 cadI 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_02522 1.6e-54 arsR K ArsR family transcriptional regulator
HIMGIKDF_02523 1.1e-152 yqcI S YqcI/YcgG family
HIMGIKDF_02524 1.6e-96 S Tetratricopeptide repeat
HIMGIKDF_02527 3.8e-277 A Pre-toxin TG
HIMGIKDF_02528 1.1e-104 S Suppressor of fused protein (SUFU)
HIMGIKDF_02530 5e-60
HIMGIKDF_02532 1.1e-144 xlyA 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HIMGIKDF_02533 2.6e-68 S Bacteriophage holin family
HIMGIKDF_02534 4.8e-165 xepA
HIMGIKDF_02535 1.3e-23
HIMGIKDF_02536 4.1e-56 xkdW S XkdW protein
HIMGIKDF_02537 2e-221
HIMGIKDF_02538 9.6e-40
HIMGIKDF_02539 9.9e-103 xkdU S Uncharacterised protein conserved in bacteria (DUF2313)
HIMGIKDF_02540 6e-191 xkdT S Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology
HIMGIKDF_02541 9.6e-71 xkdS S Protein of unknown function (DUF2634)
HIMGIKDF_02542 1.8e-38 xkdR S Protein of unknown function (DUF2577)
HIMGIKDF_02543 2.4e-181 yqbQ 3.2.1.96 G NLP P60 protein
HIMGIKDF_02544 9e-114 xkdP S Lysin motif
HIMGIKDF_02545 0.0 xkdO L Transglycosylase SLT domain
HIMGIKDF_02546 1.8e-67 S Phage XkdN-like tail assembly chaperone protein, TAC
HIMGIKDF_02548 3.6e-76 xkdM S Phage tail tube protein
HIMGIKDF_02549 5.5e-256 xkdK S Phage tail sheath C-terminal domain
HIMGIKDF_02550 3.2e-26
HIMGIKDF_02551 1.4e-77
HIMGIKDF_02552 4.3e-94 S Bacteriophage HK97-gp10, putative tail-component
HIMGIKDF_02553 6.7e-65 yqbH S Domain of unknown function (DUF3599)
HIMGIKDF_02554 2.1e-67 S Protein of unknown function (DUF3199)
HIMGIKDF_02555 3.6e-51 S YqbF, hypothetical protein domain
HIMGIKDF_02556 1.9e-167 xkdG S Phage capsid family
HIMGIKDF_02557 5.1e-128 yqbD 2.1.1.72 L Putative phage serine protease XkdF
HIMGIKDF_02558 2e-115
HIMGIKDF_02559 5.7e-169 S Phage Mu protein F like protein
HIMGIKDF_02560 5.9e-296 yqbA S portal protein
HIMGIKDF_02561 2.4e-253 S phage terminase, large subunit
HIMGIKDF_02562 6.3e-107 yqaS L DNA packaging
HIMGIKDF_02564 6.5e-81 L Transposase
HIMGIKDF_02565 1.6e-166
HIMGIKDF_02566 2.1e-31 yqaO S Phage-like element PBSX protein XtrA
HIMGIKDF_02567 7.2e-74 rusA L Endodeoxyribonuclease RusA
HIMGIKDF_02569 5.9e-168 xkdC L IstB-like ATP binding protein
HIMGIKDF_02570 4.7e-123 3.1.3.16 L DnaD domain protein
HIMGIKDF_02571 2.5e-155 recT L RecT family
HIMGIKDF_02572 1.5e-180 yqaJ L YqaJ-like viral recombinase domain
HIMGIKDF_02576 1.2e-103
HIMGIKDF_02578 6.5e-37 K Helix-turn-helix XRE-family like proteins
HIMGIKDF_02579 1.1e-56 K sequence-specific DNA binding
HIMGIKDF_02581 1e-101 adk 2.7.4.3 F adenylate kinase activity
HIMGIKDF_02582 1.4e-100 yqaB E IrrE N-terminal-like domain
HIMGIKDF_02583 2.2e-61 sigK K sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HIMGIKDF_02584 2e-68 psiE S Protein PsiE homolog
HIMGIKDF_02585 9e-237 yrkQ T Histidine kinase
HIMGIKDF_02586 1.1e-127 T Transcriptional regulator
HIMGIKDF_02587 8.2e-224 yrkO P Protein of unknown function (DUF418)
HIMGIKDF_02588 6e-105 yrkN K Acetyltransferase (GNAT) family
HIMGIKDF_02589 1.5e-97 ywrO S Flavodoxin-like fold
HIMGIKDF_02590 2.8e-79 S Protein of unknown function with HXXEE motif
HIMGIKDF_02591 4.3e-117 yrkJ S membrane transporter protein
HIMGIKDF_02592 2.4e-36 yrkI O Belongs to the sulfur carrier protein TusA family
HIMGIKDF_02593 1.1e-219 yrkH P Rhodanese Homology Domain
HIMGIKDF_02594 1.7e-99 yrkF OP Belongs to the sulfur carrier protein TusA family
HIMGIKDF_02595 5.1e-84 yrkE O DsrE/DsrF/DrsH-like family
HIMGIKDF_02596 7.8e-39 yrkD S protein conserved in bacteria
HIMGIKDF_02597 2.6e-108 yrkC G Cupin domain
HIMGIKDF_02598 4.8e-151 bltR K helix_turn_helix, mercury resistance
HIMGIKDF_02599 3.5e-211 blt EGP Major facilitator Superfamily
HIMGIKDF_02600 1.4e-83 bltD 2.3.1.57 K FR47-like protein
HIMGIKDF_02601 4.5e-236 corC1 S COG1253 Hemolysins and related proteins containing CBS domains
HIMGIKDF_02602 2.1e-17 S YrzO-like protein
HIMGIKDF_02603 1.7e-171 yrdR EG EamA-like transporter family
HIMGIKDF_02604 5.9e-160 yrdQ K Transcriptional regulator
HIMGIKDF_02605 2e-199 trkA P Oxidoreductase
HIMGIKDF_02606 3.5e-158 czcD P COG1230 Co Zn Cd efflux system component
HIMGIKDF_02607 1.3e-66 yodA S tautomerase
HIMGIKDF_02608 7.7e-163 gltR K LysR substrate binding domain
HIMGIKDF_02610 1.5e-231 brnQ E Component of the transport system for branched-chain amino acids
HIMGIKDF_02611 2.5e-50 azlD E Branched-chain amino acid transport protein (AzlD)
HIMGIKDF_02612 3.3e-138 azlC E AzlC protein
HIMGIKDF_02613 2.2e-79 bkdR K helix_turn_helix ASNC type
HIMGIKDF_02614 4.1e-46 yrdF K ribonuclease inhibitor
HIMGIKDF_02615 4.1e-231 cypA C Cytochrome P450
HIMGIKDF_02617 3.1e-101 yrdC 3.5.1.19 Q Isochorismatase family
HIMGIKDF_02618 1.9e-57 S Protein of unknown function (DUF2568)
HIMGIKDF_02619 1.2e-91 yrdA S DinB family
HIMGIKDF_02620 7.6e-168 aadK G Streptomycin adenylyltransferase
HIMGIKDF_02621 1.5e-194 yrpB 1.13.12.16 S COG2070 Dioxygenases related to 2-nitropropane dioxygenase
HIMGIKDF_02622 7.4e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIMGIKDF_02623 3e-125 yrpD S Domain of unknown function, YrpD
HIMGIKDF_02625 5.4e-117 adcA S ZinT (YodA) periplasmic lipocalin-like zinc-recruitment
HIMGIKDF_02626 6.3e-96 sigZ K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_02627 4.5e-188 yrpG C Aldo/keto reductase family
HIMGIKDF_02628 9.5e-226 yraO C Citrate transporter
HIMGIKDF_02629 1.2e-163 yraN K Transcriptional regulator
HIMGIKDF_02630 2.4e-206 yraM S PrpF protein
HIMGIKDF_02632 2.7e-157 csn 3.2.1.132 M Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan
HIMGIKDF_02633 7.6e-42 yraL S COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_02634 3.2e-155 S Alpha beta hydrolase
HIMGIKDF_02635 1.7e-60 T sh3 domain protein
HIMGIKDF_02636 2.4e-61 T sh3 domain protein
HIMGIKDF_02637 1.3e-66 E Glyoxalase-like domain
HIMGIKDF_02638 5.3e-37 yraG
HIMGIKDF_02639 6.4e-63 yraF M Spore coat protein
HIMGIKDF_02640 2.9e-223 adhB 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIMGIKDF_02641 2.6e-26 yraE
HIMGIKDF_02642 1.1e-49 yraD M Spore coat protein
HIMGIKDF_02643 4.3e-47 yraB K helix_turn_helix, mercury resistance
HIMGIKDF_02644 3.2e-29 yphJ 4.1.1.44 S peroxiredoxin activity
HIMGIKDF_02645 1.9e-200 adhA 1.1.1.1 C alcohol dehydrogenase
HIMGIKDF_02646 5e-90 yhbO 1.11.1.6, 3.5.1.124 S protease
HIMGIKDF_02647 0.0 sacC 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HIMGIKDF_02648 1.5e-152 manZ G COG3716 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IID
HIMGIKDF_02649 4.9e-116 manY G COG3715 Phosphotransferase system, mannose fructose N-acetylgalactosamine-specific component IIC
HIMGIKDF_02650 6.3e-82 levE 2.7.1.202 G PTS system mannose fructose sorbose family
HIMGIKDF_02651 3.9e-75 levD 2.7.1.202 G PTS system fructose IIA component
HIMGIKDF_02652 0.0 levR K PTS system fructose IIA component
HIMGIKDF_02653 1.6e-255 cycA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_02654 3.6e-106 yrhP E LysE type translocator
HIMGIKDF_02655 1.1e-150 yrhO K Archaeal transcriptional regulator TrmB
HIMGIKDF_02656 4.3e-86 sigV K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_02657 1.7e-151 rsiV S Protein of unknown function (DUF3298)
HIMGIKDF_02658 0.0 yrhL I Acyltransferase family
HIMGIKDF_02659 1.5e-46 yrhK S YrhK-like protein
HIMGIKDF_02660 0.0 cypD 1.14.14.1, 1.6.2.4 C Belongs to the cytochrome P450 family
HIMGIKDF_02661 4.8e-105 Z012_03230 K Tetracycline repressor, C-terminal all-alpha domain
HIMGIKDF_02662 4.5e-97 yrhH Q methyltransferase
HIMGIKDF_02665 1.8e-142 focA P Formate nitrite
HIMGIKDF_02666 7.8e-61 yrhF S Uncharacterized conserved protein (DUF2294)
HIMGIKDF_02667 0.0 fdhA 1.17.1.10, 1.17.1.9 C formate dehydrogenase (NAD+) activity
HIMGIKDF_02668 1.4e-78 yrhD S Protein of unknown function (DUF1641)
HIMGIKDF_02669 4.6e-35 yrhC S YrhC-like protein
HIMGIKDF_02670 2.6e-211 mccB 2.5.1.48, 4.4.1.1, 4.4.1.2, 4.4.1.8 E cystathionine
HIMGIKDF_02671 1.2e-171 mccA 2.5.1.134, 2.5.1.47 E Cysteine synthase
HIMGIKDF_02672 4.2e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HIMGIKDF_02673 1.2e-120 yrrT 4.4.1.21 Q Could be a S-adenosyl-L-methionine-dependent methyltransferase
HIMGIKDF_02674 7e-27 yrzA S Protein of unknown function (DUF2536)
HIMGIKDF_02675 4.2e-63 yrrS S Protein of unknown function (DUF1510)
HIMGIKDF_02676 0.0 pbpI 3.4.16.4 M Penicillin-binding Protein
HIMGIKDF_02677 2.4e-78 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HIMGIKDF_02678 4.7e-114 udk 2.7.1.48 F Cytidine monophosphokinase
HIMGIKDF_02679 2.7e-246 yegQ O COG0826 Collagenase and related proteases
HIMGIKDF_02680 7.8e-174 yegQ O Peptidase U32
HIMGIKDF_02681 5.9e-120 yrrM 2.1.1.104 S O-methyltransferase
HIMGIKDF_02682 1.6e-183 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HIMGIKDF_02683 1.2e-45 yrzB S Belongs to the UPF0473 family
HIMGIKDF_02684 2.1e-70 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HIMGIKDF_02685 1.7e-41 yrzL S Belongs to the UPF0297 family
HIMGIKDF_02686 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HIMGIKDF_02687 2.7e-170 yrrI S AI-2E family transporter
HIMGIKDF_02688 1.3e-131 glnQ 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMGIKDF_02689 5.1e-145 glnH ET Belongs to the bacterial solute-binding protein 3 family
HIMGIKDF_02690 3.6e-109 gluC P ABC transporter
HIMGIKDF_02691 7.6e-107 glnP P ABC transporter
HIMGIKDF_02692 8e-08 S Protein of unknown function (DUF3918)
HIMGIKDF_02693 9.8e-31 yrzR
HIMGIKDF_02694 1.8e-83 yrrD S protein conserved in bacteria
HIMGIKDF_02695 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HIMGIKDF_02696 1.4e-15 S COG0457 FOG TPR repeat
HIMGIKDF_02697 2.3e-220 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HIMGIKDF_02698 4.7e-213 iscS 2.8.1.7 E Cysteine desulfurase
HIMGIKDF_02699 1.2e-70 cymR K Transcriptional regulator
HIMGIKDF_02700 2e-236 rarA L COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase
HIMGIKDF_02701 2.8e-137 yrvM H COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1
HIMGIKDF_02702 0.0 aspS 6.1.1.12 J Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HIMGIKDF_02703 5.2e-245 hisS 6.1.1.21 J histidyl-tRNA synthetase
HIMGIKDF_02705 3.9e-263 lytH 3.5.1.28 M COG3103 SH3 domain protein
HIMGIKDF_02706 1.9e-68 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HIMGIKDF_02707 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HIMGIKDF_02708 5.9e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HIMGIKDF_02709 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HIMGIKDF_02710 1.3e-48 yrvD S Lipopolysaccharide assembly protein A domain
HIMGIKDF_02711 1.7e-87 yrvC P regulatory, ligand-binding protein related to C-terminal domains of K channels
HIMGIKDF_02712 0.0 secF U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HIMGIKDF_02713 9.4e-49 yrzD S Post-transcriptional regulator
HIMGIKDF_02714 5.7e-270 spoVB S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_02715 2.2e-114 yrbG S membrane
HIMGIKDF_02716 1.2e-74 yrzE S Protein of unknown function (DUF3792)
HIMGIKDF_02717 1.1e-38 yajC U Preprotein translocase subunit YajC
HIMGIKDF_02718 5.2e-228 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HIMGIKDF_02719 2e-194 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HIMGIKDF_02720 2.6e-18 yrzS S Protein of unknown function (DUF2905)
HIMGIKDF_02721 6.6e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HIMGIKDF_02722 1.6e-106 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HIMGIKDF_02723 4.8e-93 bofC S BofC C-terminal domain
HIMGIKDF_02724 5.3e-253 csbX EGP Major facilitator Superfamily
HIMGIKDF_02725 1.3e-193 iolG 1.1.1.18, 1.1.1.369 S Oxidoreductase family, NAD-binding Rossmann fold
HIMGIKDF_02726 6.5e-119 yrzF T serine threonine protein kinase
HIMGIKDF_02728 2.6e-35 S Family of unknown function (DUF5412)
HIMGIKDF_02729 1.8e-262 alsT E Sodium alanine symporter
HIMGIKDF_02730 1.9e-127 yebC K transcriptional regulatory protein
HIMGIKDF_02731 3.8e-49 S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMGIKDF_02732 9.8e-158 safA M spore coat assembly protein SafA
HIMGIKDF_02733 2.8e-215 nadA 2.5.1.72 H Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HIMGIKDF_02734 5.4e-161 nadC 1.4.3.16, 2.4.2.19 H Belongs to the NadC ModD family
HIMGIKDF_02735 2.7e-307 nadB 1.3.5.4, 1.4.3.16 H Catalyzes the oxidation of L-aspartate to iminoaspartate
HIMGIKDF_02736 1.2e-230 nifS 2.8.1.7 E Cysteine desulfurase
HIMGIKDF_02737 3.6e-94 niaR S small molecule binding protein (contains 3H domain)
HIMGIKDF_02738 3.4e-163 pheA 4.2.1.51 E Prephenate dehydratase
HIMGIKDF_02739 2.2e-73 pheB 5.4.99.5 S Belongs to the UPF0735 family
HIMGIKDF_02740 1.5e-231 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HIMGIKDF_02741 1.5e-106 spo0B T Sporulation initiation phospho-transferase B, C-terminal
HIMGIKDF_02742 2.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HIMGIKDF_02743 4.1e-56 ysxB J ribosomal protein
HIMGIKDF_02744 5.8e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HIMGIKDF_02745 9.2e-161 spoIVFB S Stage IV sporulation protein
HIMGIKDF_02746 3.8e-145 spoIVFA M COG0739 Membrane proteins related to metalloendopeptidases
HIMGIKDF_02747 2.5e-144 minD D Belongs to the ParA family
HIMGIKDF_02748 1.4e-108 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HIMGIKDF_02749 1.4e-84 mreD M shape-determining protein
HIMGIKDF_02750 2.8e-157 mreC M Involved in formation and maintenance of cell shape
HIMGIKDF_02751 1.8e-184 mreB D Rod shape-determining protein MreB
HIMGIKDF_02752 5.9e-126 radC E Belongs to the UPF0758 family
HIMGIKDF_02753 2.8e-102 maf D septum formation protein Maf
HIMGIKDF_02754 1.1e-168 spoIIB S Sporulation related domain
HIMGIKDF_02755 6.6e-85 comC 3.4.23.43 NOU COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases
HIMGIKDF_02756 4.3e-247 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HIMGIKDF_02757 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HIMGIKDF_02758 1.6e-25
HIMGIKDF_02759 1.6e-199 ysxE S A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HIMGIKDF_02760 1.9e-226 spoVID M stage VI sporulation protein D
HIMGIKDF_02761 4.6e-249 hemL 5.4.3.8 H Glutamate-1-semialdehyde aminotransferase
HIMGIKDF_02762 5.6e-183 hemB 4.2.1.24 H Belongs to the ALAD family
HIMGIKDF_02763 4.4e-146 hemD 2.1.1.107, 4.2.1.75 H Uroporphyrinogen-III synthase
HIMGIKDF_02764 3e-173 hemC 2.1.1.107, 2.5.1.61, 4.2.1.75 H Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps
HIMGIKDF_02765 3.6e-146 hemX O cytochrome C
HIMGIKDF_02766 3.5e-247 hemA 1.2.1.70 H Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HIMGIKDF_02767 1.4e-89 ysxD
HIMGIKDF_02768 1.2e-106 engB D Necessary for normal cell division and for the maintenance of normal septation
HIMGIKDF_02769 0.0 lon 3.4.21.53 O ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HIMGIKDF_02770 2.3e-311 lonB 2.7.7.7, 3.4.21.53 LO Belongs to the peptidase S16 family
HIMGIKDF_02771 3.4e-233 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HIMGIKDF_02772 8.3e-227 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HIMGIKDF_02773 2.3e-187 ysoA H Tetratricopeptide repeat
HIMGIKDF_02774 8.1e-116 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIMGIKDF_02775 1.7e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HIMGIKDF_02776 3.3e-200 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
HIMGIKDF_02777 4e-292 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HIMGIKDF_02778 3.1e-192 ilvC 1.1.1.86 EH Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HIMGIKDF_02779 3.2e-84 ilvN 2.2.1.6 E Acetolactate synthase
HIMGIKDF_02780 0.0 ilvB 2.2.1.6 E Acetolactate synthase
HIMGIKDF_02782 7.6e-82 ysnE K acetyltransferase
HIMGIKDF_02783 9.1e-134 ysnF S protein conserved in bacteria
HIMGIKDF_02785 1.4e-92 ysnB S Phosphoesterase
HIMGIKDF_02786 4.5e-103 rdgB 3.6.1.66 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HIMGIKDF_02787 1.8e-133 rph 2.7.7.56, 3.6.1.66 J Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HIMGIKDF_02788 2.9e-196 gerM S COG5401 Spore germination protein
HIMGIKDF_02789 2.1e-154 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HIMGIKDF_02790 2.3e-75 ysmB 2.4.2.28 K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_02791 3.3e-30 gerE K Transcriptional regulator
HIMGIKDF_02792 7.7e-79 ybgC 3.1.2.23, 3.1.2.28 S thioesterase
HIMGIKDF_02793 4.6e-148 sdhB 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HIMGIKDF_02794 0.0 sdhA 1.3.5.1, 1.3.5.4 C succinate dehydrogenase
HIMGIKDF_02795 2.4e-107 sdhC C succinate dehydrogenase
HIMGIKDF_02796 1.2e-79 yslB S Protein of unknown function (DUF2507)
HIMGIKDF_02797 1.3e-216 lysC 1.1.1.3, 2.7.2.4 E Belongs to the aspartokinase family
HIMGIKDF_02798 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HIMGIKDF_02799 2e-52 trxA O Belongs to the thioredoxin family
HIMGIKDF_02800 4e-305 xsa 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HIMGIKDF_02802 4.2e-178 etfA C Electron transfer flavoprotein
HIMGIKDF_02803 1.2e-135 etfB C Electron transfer flavoprotein
HIMGIKDF_02804 3.1e-136 fadB 4.2.1.17 I Belongs to the enoyl-CoA hydratase isomerase family
HIMGIKDF_02805 2.7e-100 fadR K Transcriptional regulator
HIMGIKDF_02806 0.0 lcfA 6.2.1.3 IQ COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
HIMGIKDF_02807 7.3e-68 yshE S membrane
HIMGIKDF_02808 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HIMGIKDF_02809 0.0 polX L COG1796 DNA polymerase IV (family X)
HIMGIKDF_02810 1.3e-85 cvpA S membrane protein, required for colicin V production
HIMGIKDF_02811 2.4e-40 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HIMGIKDF_02812 4e-170 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HIMGIKDF_02813 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMGIKDF_02814 2.8e-196 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HIMGIKDF_02815 3.1e-133 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HIMGIKDF_02816 2.6e-32 sspI S Belongs to the SspI family
HIMGIKDF_02817 4.4e-208 ysfB KT regulator
HIMGIKDF_02818 7.2e-264 glcD 1.1.3.15 C Glycolate oxidase subunit
HIMGIKDF_02819 5.6e-258 glcF C Glycolate oxidase
HIMGIKDF_02820 3.6e-38 ysfE 4.4.1.5 E lactoylglutathione lyase activity
HIMGIKDF_02822 0.0 cstA T Carbon starvation protein
HIMGIKDF_02823 4.6e-301 abfA 3.2.1.55 GH51 G alpha-L-arabinofuranosidase activity
HIMGIKDF_02824 3.4e-144 araQ G transport system permease
HIMGIKDF_02825 1.4e-167 araP G carbohydrate transport
HIMGIKDF_02826 2.8e-254 araN G carbohydrate transport
HIMGIKDF_02827 5e-226 egsA 1.1.1.261 I Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is probably used for the synthesis of phosphoglycerolipids in Gram-positive bacterial species
HIMGIKDF_02828 4.1e-147 araL 3.1.3.41 G Haloacid dehalogenase-like hydrolase
HIMGIKDF_02829 8.4e-133 araD 4.1.2.17, 4.2.1.109, 5.1.3.4 G COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases
HIMGIKDF_02830 0.0 araB 2.7.1.16 C Belongs to the ribulokinase family
HIMGIKDF_02831 1.9e-294 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HIMGIKDF_02832 2.1e-190 abnA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMGIKDF_02833 4.5e-205 ysdC G COG1363 Cellulase M and related proteins
HIMGIKDF_02834 9.2e-68 ysdB S Sigma-w pathway protein YsdB
HIMGIKDF_02835 7.5e-45 ysdA S Membrane
HIMGIKDF_02836 3.6e-58 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HIMGIKDF_02837 9e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HIMGIKDF_02838 3.3e-86 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HIMGIKDF_02840 2.4e-111 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HIMGIKDF_02841 2.2e-49 lrgA S Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgB, with the holin-like protein CidA. The LrgAB and CidA proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
HIMGIKDF_02842 6.3e-131 lytT T COG3279 Response regulator of the LytR AlgR family
HIMGIKDF_02843 0.0 lytS 2.7.13.3 T Histidine kinase
HIMGIKDF_02844 1.5e-149 ysaA S HAD-hyrolase-like
HIMGIKDF_02845 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIMGIKDF_02846 3.8e-159 ytxC S YtxC-like family
HIMGIKDF_02847 4.9e-111 ytxB S SNARE associated Golgi protein
HIMGIKDF_02848 3e-173 dnaI L Primosomal protein DnaI
HIMGIKDF_02849 3.5e-266 dnaB L Membrane attachment protein
HIMGIKDF_02850 1.1e-80 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HIMGIKDF_02851 2e-67 speH 4.1.1.50 E Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HIMGIKDF_02852 2.8e-193 gapB 1.2.1.12, 1.2.1.59 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMGIKDF_02853 9.9e-67 ytcD K Transcriptional regulator
HIMGIKDF_02854 4.9e-205 ytbD EGP Major facilitator Superfamily
HIMGIKDF_02855 8.9e-161 ytbE S reductase
HIMGIKDF_02856 7.6e-98 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HIMGIKDF_02857 1.1e-107 ytaF P Probably functions as a manganese efflux pump
HIMGIKDF_02858 2e-157 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HIMGIKDF_02859 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HIMGIKDF_02860 0.0 phoR 2.7.13.3 T Signal transduction histidine kinase
HIMGIKDF_02861 2.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_02862 1.1e-170 mdh 1.1.1.37 C Catalyzes the reversible oxidation of malate to oxaloacetate
HIMGIKDF_02863 1.8e-242 icd 1.1.1.42 C isocitrate
HIMGIKDF_02864 4.7e-210 citZ 2.3.3.1 C Belongs to the citrate synthase family
HIMGIKDF_02865 4.7e-71 yeaL S membrane
HIMGIKDF_02866 2.6e-192 ytvI S sporulation integral membrane protein YtvI
HIMGIKDF_02867 1.8e-63 fxsA S COG3030 Protein affecting phage T7 exclusion by the F plasmid
HIMGIKDF_02868 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HIMGIKDF_02869 3.4e-180 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
HIMGIKDF_02870 4.3e-183 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
HIMGIKDF_02871 8.4e-162 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HIMGIKDF_02872 1.5e-225 ytsJ 1.1.1.38 C Malate dehydrogenase
HIMGIKDF_02873 0.0 dnaE 2.7.7.7 L DNA polymerase
HIMGIKDF_02874 3.2e-56 ytrH S Sporulation protein YtrH
HIMGIKDF_02875 8.2e-69 ytrI
HIMGIKDF_02876 9.2e-29
HIMGIKDF_02877 7.8e-182 nrnA 3.1.13.3, 3.1.3.7 S COG0618 Exopolyphosphatase-related proteins
HIMGIKDF_02878 2.4e-47 ytpI S YtpI-like protein
HIMGIKDF_02879 8e-241 ytoI K transcriptional regulator containing CBS domains
HIMGIKDF_02880 1.2e-158 ytnM S membrane transporter protein
HIMGIKDF_02881 4.9e-240 ytnL 3.5.1.47 E hydrolase activity
HIMGIKDF_02882 6.3e-128 ribF 2.7.1.26, 2.7.7.2 H Riboflavin kinase
HIMGIKDF_02883 1e-256 moxC C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_02884 2.9e-47 ytnI O COG0695 Glutaredoxin and related proteins
HIMGIKDF_02885 1.2e-185 ytmO C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_02886 1e-142 tcyN 3.6.3.21 E COG1126 ABC-type polar amino acid transport system, ATPase component
HIMGIKDF_02887 7.6e-121 tcyM U Binding-protein-dependent transport system inner membrane component
HIMGIKDF_02888 3.7e-123 tcyL P Binding-protein-dependent transport system inner membrane component
HIMGIKDF_02889 1.5e-149 tcyK M Bacterial periplasmic substrate-binding proteins
HIMGIKDF_02890 9.5e-152 tcyK ET Bacterial periplasmic substrate-binding proteins
HIMGIKDF_02891 1.5e-100 ytmI K Acetyltransferase (GNAT) domain
HIMGIKDF_02892 2.9e-173 ytlI K LysR substrate binding domain
HIMGIKDF_02893 1.7e-130 ytkL S Belongs to the UPF0173 family
HIMGIKDF_02894 1.1e-141 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_02896 3.1e-267 argH 4.3.2.1 E argininosuccinate lyase
HIMGIKDF_02897 2.3e-234 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
HIMGIKDF_02898 3.6e-88 moaB 2.7.7.75 H May be involved in the biosynthesis of molybdopterin
HIMGIKDF_02899 3.7e-221 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HIMGIKDF_02900 7e-165 ytxK 2.1.1.72 L DNA methylase
HIMGIKDF_02901 2.4e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HIMGIKDF_02902 8.7e-70 ytfJ S Sporulation protein YtfJ
HIMGIKDF_02903 5.6e-116 ytfI S Protein of unknown function (DUF2953)
HIMGIKDF_02904 1.3e-87 yteJ S RDD family
HIMGIKDF_02905 2.4e-181 sppA OU signal peptide peptidase SppA
HIMGIKDF_02906 2.2e-148 nadK 2.7.1.23 G Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HIMGIKDF_02907 0.0 ytcJ S amidohydrolase
HIMGIKDF_02908 2e-307 acsA 6.2.1.1, 6.2.1.2 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIMGIKDF_02909 2e-29 sspB S spore protein
HIMGIKDF_02910 3.5e-227 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HIMGIKDF_02911 2.2e-210 iscS2 2.8.1.7 E Cysteine desulfurase
HIMGIKDF_02912 4.9e-238 brnQ E Component of the transport system for branched-chain amino acids
HIMGIKDF_02913 4.1e-274 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HIMGIKDF_02914 1.6e-154 hisK 3.1.3.15 E COG1387 Histidinol phosphatase and related hydrolases of the PHP family
HIMGIKDF_02915 3.4e-109 yttP K Transcriptional regulator
HIMGIKDF_02916 1.2e-88 ytsP 1.8.4.14 T GAF domain-containing protein
HIMGIKDF_02917 0.0 ytrP 2.7.7.65 T COG2199 FOG GGDEF domain
HIMGIKDF_02918 2.5e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HIMGIKDF_02920 3.6e-238 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIMGIKDF_02921 0.0 acsA 6.2.1.1 I COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases
HIMGIKDF_02922 3.6e-122 acuA K Part of the acuABC operon, which is possibly involved in the breakdown of acetoin and butanediol. Acts as an acetyltransferase inactivating acetyl-CoA synthetase AcsA via acetylation at a Lys residue
HIMGIKDF_02923 1.6e-117 acuB S Domain in cystathionine beta-synthase and other proteins.
HIMGIKDF_02924 1.9e-225 acuC BQ histone deacetylase
HIMGIKDF_02925 1.4e-125 motS N Flagellar motor protein
HIMGIKDF_02926 7.1e-147 motA N flagellar motor
HIMGIKDF_02927 1.7e-182 ccpA K catabolite control protein A
HIMGIKDF_02928 4.9e-196 aroF 2.5.1.54, 5.4.99.5 E Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate
HIMGIKDF_02929 4.4e-55 ytxJ O Protein of unknown function (DUF2847)
HIMGIKDF_02930 6.6e-17 ytxH S COG4980 Gas vesicle protein
HIMGIKDF_02931 2.1e-17 ytxG S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HIMGIKDF_02932 1.6e-254 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HIMGIKDF_02933 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HIMGIKDF_02934 9.7e-109 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HIMGIKDF_02935 9.8e-149 ytpQ S Belongs to the UPF0354 family
HIMGIKDF_02936 2.1e-57 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HIMGIKDF_02937 5.9e-79 ytoQ S Nucleoside 2-deoxyribosyltransferase YtoQ
HIMGIKDF_02938 4.7e-207 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
HIMGIKDF_02939 9.8e-52 ytzB S small secreted protein
HIMGIKDF_02940 0.0 sfcA 1.1.1.38 C Malate dehydrogenase
HIMGIKDF_02941 6.4e-151 ytnP S COG0491 Zn-dependent hydrolases, including glyoxylases
HIMGIKDF_02942 1.4e-121 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HIMGIKDF_02943 2e-45 ytzH S YtzH-like protein
HIMGIKDF_02944 6.1e-151 ytmP 2.7.1.89 M Phosphotransferase
HIMGIKDF_02945 0.0 pulA 3.2.1.41 CBM48,GH13 G Belongs to the glycosyl hydrolase 13 family
HIMGIKDF_02946 2.9e-181 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic domain
HIMGIKDF_02947 1.3e-165 ytlQ
HIMGIKDF_02948 4.3e-103 ligT 3.1.4.58, 3.5.1.42 J Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
HIMGIKDF_02949 8.6e-173 ytkP 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
HIMGIKDF_02950 7.1e-272 pepV 3.5.1.18 E Dipeptidase
HIMGIKDF_02951 7.2e-226 pbuO S permease
HIMGIKDF_02952 3.9e-207 ythQ U Bacterial ABC transporter protein EcsB
HIMGIKDF_02953 4.3e-132 ythP V ABC transporter
HIMGIKDF_02954 2.4e-33 ytzE K COG1349 Transcriptional regulators of sugar metabolism
HIMGIKDF_02955 2.6e-132 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HIMGIKDF_02956 1.9e-281 ytgP S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_02957 8.2e-232 ytfP S HI0933-like protein
HIMGIKDF_02958 3.4e-283 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
HIMGIKDF_02959 3.1e-26 yteV S Sporulation protein Cse60
HIMGIKDF_02960 4.8e-117 yteU S Integral membrane protein
HIMGIKDF_02961 2.6e-249 yteT S Oxidoreductase family, C-terminal alpha/beta domain
HIMGIKDF_02962 4.6e-73 yteS G transport
HIMGIKDF_02963 4.7e-226 yteR 3.2.1.172 GH105 G unsaturated glucuronyl hydrolase involved in regulation of bacterial surface properties, and related proteins
HIMGIKDF_02964 2e-172 lplB G COG4209 ABC-type polysaccharide transport system, permease component
HIMGIKDF_02965 0.0 ytdP K Transcriptional regulator
HIMGIKDF_02966 1.2e-290 ytcQ G COG1653 ABC-type sugar transport system, periplasmic component
HIMGIKDF_02967 1.5e-150 ytcP G COG0395 ABC-type sugar transport system, permease component
HIMGIKDF_02968 9.6e-138 udh 1.1.1.203, 1.1.1.388 GM NAD dependent epimerase/dehydratase family
HIMGIKDF_02969 1.9e-225 bioI 1.14.14.46 C Cytochrome P450
HIMGIKDF_02970 2.2e-190 bioB 2.8.1.6 H Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HIMGIKDF_02971 3.7e-128 bioD 6.3.3.3 H Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HIMGIKDF_02972 1.4e-220 bioF 2.3.1.29, 2.3.1.47, 6.2.1.14 H Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide
HIMGIKDF_02973 2.4e-261 bioA 2.6.1.105, 2.6.1.62 H Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor
HIMGIKDF_02974 1.6e-142 bioW 2.3.1.47, 6.2.1.14 H Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
HIMGIKDF_02975 1.3e-173 ytaP S Acetyl xylan esterase (AXE1)
HIMGIKDF_02976 2.3e-190 msmR K Transcriptional regulator
HIMGIKDF_02977 2.3e-248 msmE G Bacterial extracellular solute-binding protein
HIMGIKDF_02978 1.5e-169 amyD P ABC transporter
HIMGIKDF_02979 1.5e-144 amyC P ABC transporter (permease)
HIMGIKDF_02980 4e-253 melA 3.2.1.122, 3.2.1.22, 3.2.1.86 GH4,GT4 G Family 4 glycosyl hydrolase
HIMGIKDF_02981 2.1e-51 ytwF P Sulfurtransferase
HIMGIKDF_02982 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HIMGIKDF_02983 7.7e-55 ytvB S Protein of unknown function (DUF4257)
HIMGIKDF_02984 6e-143 pfyP T Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
HIMGIKDF_02985 2.1e-211 yttB EGP Major facilitator Superfamily
HIMGIKDF_02986 1.8e-43 yttA 2.7.13.3 S Pfam Transposase IS66
HIMGIKDF_02987 0.0 bceB V ABC transporter (permease)
HIMGIKDF_02988 1.1e-138 bceA V ABC transporter, ATP-binding protein
HIMGIKDF_02989 5.6e-186 T PhoQ Sensor
HIMGIKDF_02990 5.2e-130 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_02991 8.5e-235 ytrF V COG0577 ABC-type antimicrobial peptide transport system, permease component
HIMGIKDF_02992 3.1e-127 ytrE V ABC transporter, ATP-binding protein
HIMGIKDF_02993 5.9e-148
HIMGIKDF_02994 6.1e-169 P ABC-2 family transporter protein
HIMGIKDF_02995 1.1e-161 ytrB P abc transporter atp-binding protein
HIMGIKDF_02996 5.1e-66 ytrA K GntR family transcriptional regulator
HIMGIKDF_02998 6.7e-41 ytzC S Protein of unknown function (DUF2524)
HIMGIKDF_02999 2.1e-190 yhcC S Fe-S oxidoreductase
HIMGIKDF_03000 3.3e-106 ytqB J Putative rRNA methylase
HIMGIKDF_03001 2e-216 ytpB 4.2.3.130 S Tetraprenyl-beta-curcumene synthase
HIMGIKDF_03002 3.3e-149 ytpA 3.1.1.5 I Alpha beta hydrolase
HIMGIKDF_03003 1.6e-59 ytoA S COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HIMGIKDF_03004 8.4e-257 ytnA E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_03005 0.0 asnB 6.3.5.4 E Asparagine synthase
HIMGIKDF_03006 4.3e-225 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HIMGIKDF_03007 2.2e-311 pckA 4.1.1.49 C Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
HIMGIKDF_03008 1.2e-38 ytmB S Protein of unknown function (DUF2584)
HIMGIKDF_03009 5.5e-149 ytmA E COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases
HIMGIKDF_03010 5e-190 ytlA P COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components
HIMGIKDF_03011 1.4e-144 ytlC P ABC transporter
HIMGIKDF_03012 1.8e-142 ytlD P COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component
HIMGIKDF_03013 2.8e-87 ytkD 3.6.1.55 L Belongs to the Nudix hydrolase family
HIMGIKDF_03014 5.4e-63 ytkC S Bacteriophage holin family
HIMGIKDF_03015 2.1e-76 dps P Belongs to the Dps family
HIMGIKDF_03017 3.6e-73 ytkA S YtkA-like
HIMGIKDF_03018 1.6e-87 luxS 4.4.1.21 T Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HIMGIKDF_03019 5.7e-103 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HIMGIKDF_03020 3.6e-41 rpmE2 J Ribosomal protein L31
HIMGIKDF_03021 4.7e-249 cydA 1.10.3.14 C oxidase, subunit
HIMGIKDF_03022 7.3e-189 cydB 1.10.3.14 C COG1294 Cytochrome bd-type quinol oxidase, subunit 2
HIMGIKDF_03023 1.1e-24 S Domain of Unknown Function (DUF1540)
HIMGIKDF_03024 1.4e-151 troD P 'COG1108 ABC-type Mn2 Zn2 transport systems, permease components'
HIMGIKDF_03025 3.2e-234 mntC P COG1108 ABC-type Mn2 Zn2 transport systems, permease components
HIMGIKDF_03026 1.2e-140 mntB P 'COG1121 ABC-type Mn Zn transport systems, ATPase component'
HIMGIKDF_03027 1.8e-170 troA P Belongs to the bacterial solute-binding protein 9 family
HIMGIKDF_03028 1.4e-214 menC 4.2.1.113 H Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)
HIMGIKDF_03029 2.4e-278 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HIMGIKDF_03030 4.2e-155 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HIMGIKDF_03031 3.8e-156 menH 4.2.99.20 S Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC)
HIMGIKDF_03032 0.0 menD 2.2.1.9 H Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HIMGIKDF_03033 8.5e-273 menF 5.4.4.2 HQ Isochorismate synthase
HIMGIKDF_03034 2.6e-132 dksA T COG1734 DnaK suppressor protein
HIMGIKDF_03035 1e-153 galU 2.7.7.9 M Nucleotidyl transferase
HIMGIKDF_03036 1.5e-244 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIMGIKDF_03037 3.9e-181 ytcB 5.1.3.2 M NAD-dependent epimerase dehydratase
HIMGIKDF_03038 3.6e-235 ytcC M Glycosyltransferase Family 4
HIMGIKDF_03040 2.3e-206 cotS S Seems to be required for the assembly of the CotSA protein in spores
HIMGIKDF_03041 1.8e-217 cotSA M Glycosyl transferases group 1
HIMGIKDF_03042 1.8e-206 cotI S Spore coat protein
HIMGIKDF_03043 9.9e-77 tspO T membrane
HIMGIKDF_03044 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
HIMGIKDF_03045 4.3e-288 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
HIMGIKDF_03046 1.3e-177 glgD 2.4.1.21, 2.7.7.27 GT5 G Glucose-1-phosphate adenylyltransferase, GlgD subunit
HIMGIKDF_03047 3.6e-197 glgC 2.7.7.27 G Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HIMGIKDF_03048 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HIMGIKDF_03057 7.8e-08
HIMGIKDF_03058 1.3e-09
HIMGIKDF_03065 2e-08
HIMGIKDF_03070 3.4e-39 S COG NOG14552 non supervised orthologous group
HIMGIKDF_03071 4.3e-90 thiT S Thiamine transporter protein (Thia_YuaJ)
HIMGIKDF_03072 3.4e-94 M1-753 M FR47-like protein
HIMGIKDF_03073 4.1e-188 yuaG 3.4.21.72 S protein conserved in bacteria
HIMGIKDF_03074 1.4e-77 yuaF OU Membrane protein implicated in regulation of membrane protease activity
HIMGIKDF_03075 3.9e-84 yuaE S DinB superfamily
HIMGIKDF_03076 7.9e-108 yuaD
HIMGIKDF_03077 2.9e-229 gbsB 1.1.1.1 C alcohol dehydrogenase
HIMGIKDF_03078 8e-282 gbsA 1.2.1.8 C Belongs to the aldehyde dehydrogenase family
HIMGIKDF_03079 1.1e-95 yuaC K Belongs to the GbsR family
HIMGIKDF_03080 2.2e-91 yuaB
HIMGIKDF_03081 5e-122 ktrA P COG0569 K transport systems, NAD-binding component
HIMGIKDF_03082 5.4e-237 ktrB P Potassium
HIMGIKDF_03083 1e-38 yiaA S yiaA/B two helix domain
HIMGIKDF_03084 6.4e-153 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMGIKDF_03085 6.2e-277 yubD P Major Facilitator Superfamily
HIMGIKDF_03086 2.6e-88 cdoA 1.13.11.20 S Cysteine dioxygenase type I
HIMGIKDF_03088 1.2e-133 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
HIMGIKDF_03089 6.3e-197 yubA S transporter activity
HIMGIKDF_03090 3.3e-183 ygjR S Oxidoreductase
HIMGIKDF_03091 1.4e-253 rhaA 2.7.1.5, 5.3.1.14 G Belongs to the rhamnose isomerase family
HIMGIKDF_03092 2.5e-55 rhaM 5.1.3.32 G Involved in the anomeric conversion of L-rhamnose
HIMGIKDF_03093 1.3e-281 rhaB 2.7.1.12, 2.7.1.17, 2.7.1.5, 5.3.1.14 G Involved in the catabolism of L-rhamnose (6-deoxy-L- mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1-hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate
HIMGIKDF_03094 1e-134 fucR K COG1349 Transcriptional regulators of sugar metabolism
HIMGIKDF_03095 0.0 rhaD 1.1.1.1, 4.1.2.19 IQ Class II Aldolase and Adducin N-terminal domain
HIMGIKDF_03096 5.1e-239 mcpA NT chemotaxis protein
HIMGIKDF_03097 2.2e-295 mcpA NT chemotaxis protein
HIMGIKDF_03098 1.5e-222 mcpA NT chemotaxis protein
HIMGIKDF_03099 3.2e-225 mcpA NT chemotaxis protein
HIMGIKDF_03100 2.6e-140 tgl 2.3.2.13 S protein-glutamine gamma-glutamyltransferase activity
HIMGIKDF_03101 1e-35
HIMGIKDF_03102 2.1e-72 yugU S Uncharacterised protein family UPF0047
HIMGIKDF_03103 0.0 yugT 3.2.1.10, 3.2.1.20 GH13,GH31 G COG0366 Glycosidases
HIMGIKDF_03104 2.6e-236 yugS S COG1253 Hemolysins and related proteins containing CBS domains
HIMGIKDF_03105 1.4e-116 yugP S Zn-dependent protease
HIMGIKDF_03106 4.6e-39
HIMGIKDF_03107 1.1e-53 mstX S Membrane-integrating protein Mistic
HIMGIKDF_03108 1.7e-182 yugO P COG1226 Kef-type K transport systems
HIMGIKDF_03109 1.3e-72 yugN S YugN-like family
HIMGIKDF_03111 4.2e-261 pgi 5.3.1.9 G Belongs to the GPI family
HIMGIKDF_03112 2.8e-229 yugK C Dehydrogenase
HIMGIKDF_03113 8.9e-228 yugJ C oxidoreductases, Fe-dependent alcohol dehydrogenase family
HIMGIKDF_03114 1.1e-34 yuzA S Domain of unknown function (DUF378)
HIMGIKDF_03115 8.9e-63 yugI 5.3.1.9 J RNA binding protein (contains ribosomal protein S1 domain)
HIMGIKDF_03116 4.3e-200 yugH 2.6.1.1 E Aminotransferase
HIMGIKDF_03117 1.6e-85 alaR K Transcriptional regulator
HIMGIKDF_03118 1e-156 yugF I Hydrolase
HIMGIKDF_03119 9.8e-42 yugE S Domain of unknown function (DUF1871)
HIMGIKDF_03120 1.8e-228 patB 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
HIMGIKDF_03121 4.6e-233 T PhoQ Sensor
HIMGIKDF_03122 2e-70 kapB G Kinase associated protein B
HIMGIKDF_03123 1.9e-115 kapD L the KinA pathway to sporulation
HIMGIKDF_03125 3.5e-186 yuxJ EGP Major facilitator Superfamily
HIMGIKDF_03126 0.0 mrcB 2.4.1.129, 3.4.16.4 GT51 M Penicillin-binding Protein
HIMGIKDF_03127 6.3e-75 yuxK S protein conserved in bacteria
HIMGIKDF_03128 6.3e-78 yufK S Family of unknown function (DUF5366)
HIMGIKDF_03129 9.9e-294 dcuS 2.7.13.3 T Signal transduction histidine kinase regulating citrate malate metabolism
HIMGIKDF_03130 2.3e-125 dcuR T COG4565 Response regulator of citrate malate metabolism
HIMGIKDF_03131 2.5e-192 tcsA S ABC-type transport system, periplasmic component surface lipoprotein
HIMGIKDF_03132 1.1e-273 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
HIMGIKDF_03133 6.5e-185 yufP S Belongs to the binding-protein-dependent transport system permease family
HIMGIKDF_03134 4.5e-169 yufQ S Belongs to the binding-protein-dependent transport system permease family
HIMGIKDF_03135 1.3e-233 maeN C COG3493 Na citrate symporter
HIMGIKDF_03136 1.9e-14
HIMGIKDF_03137 0.0 phaA 1.6.5.3 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit
HIMGIKDF_03138 5.4e-69 mrpB P Subunit B of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMGIKDF_03139 1.5e-50 phaC 1.6.5.3 P Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMGIKDF_03140 3.8e-263 mrpD CP Subunit D of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMGIKDF_03141 4.8e-79 mrpE P Subunit E of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMGIKDF_03142 7.2e-38 phaF P Subunit F of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali
HIMGIKDF_03143 5.2e-60 phaG P COG1320 Multisubunit Na H antiporter, MnhG subunit
HIMGIKDF_03144 9.2e-65 ydiI Q protein, possibly involved in aromatic compounds catabolism
HIMGIKDF_03145 5.1e-116 comA K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_03146 0.0 comP 2.7.13.3 T Histidine kinase
HIMGIKDF_03148 2.5e-162 comQ H Polyprenyl synthetase
HIMGIKDF_03150 1.1e-22 yuzC
HIMGIKDF_03151 2.2e-232 yuxH 3.1.4.52 T signal transduction protein containing EAL and modified HD-GYP domains
HIMGIKDF_03152 3.6e-266 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HIMGIKDF_03153 2.9e-104 pncA Q COG1335 Amidases related to nicotinamidase
HIMGIKDF_03154 1.6e-67 yueI S Protein of unknown function (DUF1694)
HIMGIKDF_03155 7.4e-39 yueH S YueH-like protein
HIMGIKDF_03156 2.1e-32 yueG S Spore germination protein gerPA/gerPF
HIMGIKDF_03157 1.9e-190 yueF S transporter activity
HIMGIKDF_03158 6.1e-72 S Protein of unknown function (DUF2283)
HIMGIKDF_03159 2.9e-24 S Protein of unknown function (DUF2642)
HIMGIKDF_03160 4.8e-96 yueE S phosphohydrolase
HIMGIKDF_03161 4.4e-132 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_03162 6.6e-65 yueC S Family of unknown function (DUF5383)
HIMGIKDF_03163 0.0 esaA S type VII secretion protein EsaA
HIMGIKDF_03164 0.0 essC D COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins
HIMGIKDF_03165 2.3e-211 essB S WXG100 protein secretion system (Wss), protein YukC
HIMGIKDF_03166 7.7e-41 yukD S WXG100 protein secretion system (Wss), protein YukD
HIMGIKDF_03167 2.8e-45 esxA S Belongs to the WXG100 family
HIMGIKDF_03168 6.5e-229 yukF QT Transcriptional regulator
HIMGIKDF_03169 1.2e-205 ald 1.4.1.1 E Belongs to the AlaDH PNT family
HIMGIKDF_03170 1.1e-132 yukJ S Uncharacterized conserved protein (DUF2278)
HIMGIKDF_03171 3.8e-36 mbtH S MbtH-like protein
HIMGIKDF_03172 0.0 dhbF Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_03173 1.4e-178 entB 3.3.2.1, 6.3.2.14 Q Isochorismatase family
HIMGIKDF_03174 0.0 entE 2.7.7.58, 6.3.2.14 Q 2,3-dihydroxybenzoate-AMP ligase
HIMGIKDF_03175 2.3e-226 entC 5.4.4.2 HQ Isochorismate synthase
HIMGIKDF_03176 7.3e-141 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03177 1.3e-167 besA S Putative esterase
HIMGIKDF_03178 5.8e-122 yuiH S Oxidoreductase molybdopterin binding domain
HIMGIKDF_03179 1.1e-93 bioY S Biotin biosynthesis protein
HIMGIKDF_03180 3.9e-211 yuiF S antiporter
HIMGIKDF_03181 1.5e-280 pepA 3.4.11.1, 3.4.11.5 E Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HIMGIKDF_03182 1.2e-77 yuiD S protein conserved in bacteria
HIMGIKDF_03183 9.5e-118 yuiC S protein conserved in bacteria
HIMGIKDF_03184 8.4e-27 yuiB S Putative membrane protein
HIMGIKDF_03185 2.5e-236 yumB 1.6.99.3 C NADH dehydrogenase
HIMGIKDF_03186 3.5e-188 yumC 1.18.1.2, 1.19.1.1 C reductase
HIMGIKDF_03188 4.9e-187 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HIMGIKDF_03189 9e-118 paiB K Putative FMN-binding domain
HIMGIKDF_03190 4.7e-72 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_03191 3.7e-63 erpA S Belongs to the HesB IscA family
HIMGIKDF_03192 2.2e-162 dapF 5.1.1.7 E Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HIMGIKDF_03193 2.4e-199 yutK F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMGIKDF_03194 3.2e-39 yuzB S Belongs to the UPF0349 family
HIMGIKDF_03195 1.2e-199 yutJ 1.6.99.3 C NADH dehydrogenase
HIMGIKDF_03196 3.5e-57 yuzD S protein conserved in bacteria
HIMGIKDF_03197 1.2e-35 yutI O COG0694 Thioredoxin-like proteins and domains
HIMGIKDF_03198 0.0 yuxL 3.4.14.5, 3.4.19.1 EU peptidase
HIMGIKDF_03199 8.6e-173 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HIMGIKDF_03200 2.3e-198 thrC 4.2.3.1 E Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HIMGIKDF_03201 2.7e-241 hom 1.1.1.3 E homoserine dehydrogenase
HIMGIKDF_03202 2e-199 yutH S Spore coat protein
HIMGIKDF_03203 2.5e-77 pgpA 3.1.3.27 I COG1267 Phosphatidylglycerophosphatase A and related proteins
HIMGIKDF_03204 6.5e-142 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HIMGIKDF_03205 3.9e-75 yutE S Protein of unknown function DUF86
HIMGIKDF_03206 9.7e-48 yutD S protein conserved in bacteria
HIMGIKDF_03207 4.9e-111 yutC S Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ)
HIMGIKDF_03208 1e-167 lipA 2.8.1.8 H Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HIMGIKDF_03209 4.5e-196 lytH M Peptidase, M23
HIMGIKDF_03210 8.4e-134 yunB S Sporulation protein YunB (Spo_YunB)
HIMGIKDF_03211 4.8e-48 yunC S Domain of unknown function (DUF1805)
HIMGIKDF_03212 5.8e-266 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HIMGIKDF_03213 2e-141 yunE S membrane transporter protein
HIMGIKDF_03214 4.3e-171 yunF S Protein of unknown function DUF72
HIMGIKDF_03215 3e-62 yunG
HIMGIKDF_03216 1e-259 allB 3.5.2.5 F Catalyzes the conversion of allantoin (5- ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring
HIMGIKDF_03217 1.2e-302 pucR QT COG2508 Regulator of polyketide synthase expression
HIMGIKDF_03218 2.1e-236 pbuX F Permease family
HIMGIKDF_03219 1.3e-224 pbuX F xanthine
HIMGIKDF_03220 6.6e-284 uraD 1.7.3.3, 3.5.1.41, 4.1.1.97 Q Catalyzes the oxidation of uric acid to 5- hydroxyisourate, which is further processed to form (S)-allantoin
HIMGIKDF_03221 7.3e-61 uraH 3.5.2.17, 4.1.1.97 S Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily
HIMGIKDF_03222 7.9e-99 1.17.1.4, 1.2.5.3, 1.3.99.16 C COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs
HIMGIKDF_03223 0.0 xdhA 1.17.1.4 C COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs
HIMGIKDF_03224 3.4e-152 ygfM 1.17.1.4, 1.2.5.3 C COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs
HIMGIKDF_03225 3.6e-111 pucB 1.1.1.328, 1.17.1.4, 2.7.7.76 S MobA-like NTP transferase domain
HIMGIKDF_03226 1.7e-190 pucA 1.17.1.4 O COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
HIMGIKDF_03228 1.9e-239 pucG 2.6.1.112, 2.6.1.44, 2.6.1.45, 2.6.1.51 E COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase
HIMGIKDF_03229 1.6e-238 pucF 3.5.1.6, 3.5.1.87, 3.5.3.9 E COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases
HIMGIKDF_03230 2.4e-169 bsn L Ribonuclease
HIMGIKDF_03231 1.2e-205 msmX P Belongs to the ABC transporter superfamily
HIMGIKDF_03232 1.1e-135 yurK K UTRA
HIMGIKDF_03233 1.5e-163 yurL 2.7.1.218 G pfkB family carbohydrate kinase
HIMGIKDF_03234 7.3e-169 yurM P COG0395 ABC-type sugar transport system, permease component
HIMGIKDF_03235 1.4e-156 yurN G Binding-protein-dependent transport system inner membrane component
HIMGIKDF_03236 1.3e-240 yurO G COG1653 ABC-type sugar transport system, periplasmic component
HIMGIKDF_03237 1.8e-184 frlB M Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid
HIMGIKDF_03238 2.8e-66 yurQ 2.7.7.7 L COG0322 Nuclease subunit of the excinuclease complex
HIMGIKDF_03239 1.8e-209 yurR 1.4.5.1 E COG0665 Glycine D-amino acid oxidases (deaminating)
HIMGIKDF_03241 1e-41
HIMGIKDF_03242 7.6e-67 yurT E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_03243 3.5e-271 sufB O FeS cluster assembly
HIMGIKDF_03244 1.4e-77 nifU C COG0822 NifU homolog involved in Fe-S cluster formation
HIMGIKDF_03245 9.4e-236 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HIMGIKDF_03246 1.4e-245 sufD O assembly protein SufD
HIMGIKDF_03247 2.3e-142 sufC O COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component
HIMGIKDF_03248 1.1e-62 yurZ 2.3.1.12, 4.1.1.44 S Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HIMGIKDF_03249 1.9e-147 metQ P Belongs to the NlpA lipoprotein family
HIMGIKDF_03250 1.4e-95 metI P COG2011 ABC-type metal ion transport system, permease component
HIMGIKDF_03251 4.8e-185 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HIMGIKDF_03252 2.4e-56 yusD S SCP-2 sterol transfer family
HIMGIKDF_03253 5.6e-55 traF CO Thioredoxin
HIMGIKDF_03254 3.3e-74 rnmV 3.1.26.8 L COG1658 Small primase-like proteins (Toprim domain)
HIMGIKDF_03255 1.1e-39 yusG S Protein of unknown function (DUF2553)
HIMGIKDF_03256 9.3e-65 gcvH E Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate
HIMGIKDF_03257 2.8e-63 arsC 1.20.4.1 P Belongs to the ArsC family
HIMGIKDF_03258 0.0 fadE 1.3.8.1 I acyl-CoA dehydrogenase
HIMGIKDF_03259 4.2e-217 fadA 2.3.1.16 I Belongs to the thiolase family
HIMGIKDF_03260 0.0 fadB 1.1.1.35, 4.2.1.17, 5.1.2.3 I 3-hydroxyacyl-CoA dehydrogenase
HIMGIKDF_03261 4.7e-09 S YuzL-like protein
HIMGIKDF_03262 2.2e-165 fadM E Proline dehydrogenase
HIMGIKDF_03263 5.1e-40
HIMGIKDF_03264 3.2e-53 yusN M Coat F domain
HIMGIKDF_03265 5.4e-75 yusO K Iron dependent repressor, N-terminal DNA binding domain
HIMGIKDF_03266 3.8e-293 yusP P Major facilitator superfamily
HIMGIKDF_03267 8.4e-66 yusQ S Tautomerase enzyme
HIMGIKDF_03268 1e-63 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03269 2.5e-50 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03270 2.7e-160 yusT K LysR substrate binding domain
HIMGIKDF_03271 3.8e-47 yusU S Protein of unknown function (DUF2573)
HIMGIKDF_03272 1e-153 yusV 3.6.3.34 HP ABC transporter
HIMGIKDF_03273 5.6e-66 S YusW-like protein
HIMGIKDF_03274 6.3e-258 pepF2 E COG1164 Oligoendopeptidase F
HIMGIKDF_03275 3.9e-34 pepF2 E COG1164 Oligoendopeptidase F
HIMGIKDF_03276 4.7e-154 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03277 1.2e-79 dps P Ferritin-like domain
HIMGIKDF_03278 9.6e-237 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMGIKDF_03279 3.4e-126 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_03280 4.3e-250 cssS 2.7.13.3 T PhoQ Sensor
HIMGIKDF_03281 4.3e-158 yuxN K Transcriptional regulator
HIMGIKDF_03282 2.5e-261 fumC 1.1.1.38, 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HIMGIKDF_03283 2.3e-24 S Protein of unknown function (DUF3970)
HIMGIKDF_03284 2.2e-247 gerAA EG Spore germination protein
HIMGIKDF_03285 9.1e-198 gerAB E Spore germination protein
HIMGIKDF_03286 4.6e-189 gerAC S Spore germination B3/ GerAC like, C-terminal
HIMGIKDF_03287 1.3e-108 vraR KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_03288 5.5e-187 vraS 2.7.13.3 T Histidine kinase
HIMGIKDF_03289 5.6e-127 yvqF S Cell wall-active antibiotics response 4TMS YvqF
HIMGIKDF_03290 9.3e-129 liaG S Putative adhesin
HIMGIKDF_03291 2.5e-105 liaH KT COG1842 Phage shock protein A (IM30), suppresses sigma54-dependent transcription
HIMGIKDF_03292 5.6e-62 liaI S membrane
HIMGIKDF_03293 4.8e-227 yvqJ EGP Major facilitator Superfamily
HIMGIKDF_03294 6.5e-102 yvqK 2.5.1.17 S Adenosyltransferase
HIMGIKDF_03295 2.8e-249 yvrA 3.6.3.34 HP COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components
HIMGIKDF_03296 7.7e-186 btuC P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_03297 1.8e-170 yvrC P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
HIMGIKDF_03298 6.2e-140 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03299 1.5e-171 yvrE G SMP-30/Gluconolaconase/LRE-like region
HIMGIKDF_03300 0.0 T PhoQ Sensor
HIMGIKDF_03301 3.2e-131 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_03302 3.6e-22
HIMGIKDF_03303 1.8e-96 yvrI K RNA polymerase
HIMGIKDF_03304 2.4e-19 S YvrJ protein family
HIMGIKDF_03305 7.3e-230 oxdC 4.1.1.2 G Oxalate decarboxylase
HIMGIKDF_03306 1.3e-64 yvrL S Regulatory protein YrvL
HIMGIKDF_03307 1.8e-210 yvrN V COG0577 ABC-type antimicrobial peptide transport system, permease component
HIMGIKDF_03308 7.1e-124 macB V ABC transporter, ATP-binding protein
HIMGIKDF_03309 4.8e-176 M Efflux transporter rnd family, mfp subunit
HIMGIKDF_03310 4.4e-149 fhuC 3.6.3.34 HP ABC transporter
HIMGIKDF_03311 5.3e-176 fhuG P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_03312 9.3e-184 fhuB P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HIMGIKDF_03313 2.1e-179 fhuD P ABC transporter
HIMGIKDF_03315 2.6e-237 yvsH E Arginine ornithine antiporter
HIMGIKDF_03316 6.5e-16 S Small spore protein J (Spore_SspJ)
HIMGIKDF_03317 1e-84 yvsG S LexA-binding, inner membrane-associated putative hydrolase
HIMGIKDF_03318 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
HIMGIKDF_03319 8e-171 yvgK P COG1910 Periplasmic molybdate-binding protein domain
HIMGIKDF_03320 5.8e-138 modA P COG0725 ABC-type molybdate transport system, periplasmic component
HIMGIKDF_03321 4.7e-120 modB P COG4149 ABC-type molybdate transport system, permease component
HIMGIKDF_03322 9.1e-158 yvgN S reductase
HIMGIKDF_03323 5.4e-86 yvgO
HIMGIKDF_03324 0.0 yjcE P COG0025 NhaP-type Na H and K H antiporters
HIMGIKDF_03325 0.0 cysI 1.7.7.1, 1.8.1.2, 1.8.7.1 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate
HIMGIKDF_03326 0.0 cysJ 1.8.1.2 P Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HIMGIKDF_03327 0.0 helD 3.6.4.12 L DNA helicase
HIMGIKDF_03328 4.1e-107 yvgT S membrane
HIMGIKDF_03329 2.2e-72 bdbC O Required for disulfide bond formation in some proteins
HIMGIKDF_03330 1.6e-104 bdbD O Thioredoxin
HIMGIKDF_03331 0.0 cadA 3.6.3.3, 3.6.3.5 P COG2217 Cation transport ATPase
HIMGIKDF_03332 0.0 copA 3.6.3.54 P P-type ATPase
HIMGIKDF_03333 1.5e-29 copZ P Copper resistance protein CopZ
HIMGIKDF_03334 2.2e-48 csoR S transcriptional
HIMGIKDF_03335 2.1e-199 yvaA 1.1.1.371 S Oxidoreductase
HIMGIKDF_03336 2.4e-118 azoR I Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HIMGIKDF_03337 0.0 yvaC S Fusaric acid resistance protein-like
HIMGIKDF_03338 5.7e-73 yvaD S Family of unknown function (DUF5360)
HIMGIKDF_03339 2.8e-55 yvaE P Small Multidrug Resistance protein
HIMGIKDF_03340 4.1e-101 K Bacterial regulatory proteins, tetR family
HIMGIKDF_03341 9.1e-131 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03343 1.6e-82 smpB O Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HIMGIKDF_03344 0.0 rnr K 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HIMGIKDF_03345 5.6e-143 est 3.1.1.1 S Carboxylesterase
HIMGIKDF_03346 2.4e-23 secG U Preprotein translocase subunit SecG
HIMGIKDF_03347 3.7e-153 yvaM S Serine aminopeptidase, S33
HIMGIKDF_03348 7.5e-36 yvzC K Transcriptional
HIMGIKDF_03349 4e-69 K transcriptional
HIMGIKDF_03350 8e-70 yvaO K Cro/C1-type HTH DNA-binding domain
HIMGIKDF_03351 2.2e-54 yodB K transcriptional
HIMGIKDF_03352 4.2e-226 NT chemotaxis protein
HIMGIKDF_03353 8.1e-112 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMGIKDF_03354 1.1e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIMGIKDF_03355 2.5e-110 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMGIKDF_03356 3e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIMGIKDF_03357 8.7e-61 yvbF K Belongs to the GbsR family
HIMGIKDF_03358 7.9e-13 S Sporulation delaying protein SdpA
HIMGIKDF_03359 7.6e-172
HIMGIKDF_03360 4.4e-08
HIMGIKDF_03361 3.3e-96 sdpI S Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane
HIMGIKDF_03362 4.5e-45 sdpR K transcriptional
HIMGIKDF_03363 8.7e-114 opuCD P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMGIKDF_03364 2.5e-172 opuCC M COG1732 Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HIMGIKDF_03365 4.5e-112 opuCB P COG1174 ABC-type proline glycine betaine transport systems, permease component
HIMGIKDF_03366 8.8e-212 opuCA 3.6.3.32 E COG1125 ABC-type proline glycine betaine transport systems, ATPase components
HIMGIKDF_03367 1.4e-98 yvbF K Belongs to the GbsR family
HIMGIKDF_03368 6.4e-103 yvbG U UPF0056 membrane protein
HIMGIKDF_03369 8.6e-113 yvbH S YvbH-like oligomerisation region
HIMGIKDF_03370 4.2e-124 exoY M Membrane
HIMGIKDF_03371 0.0 tcaA S response to antibiotic
HIMGIKDF_03372 7.7e-82 yvbK 3.1.3.25 K acetyltransferase
HIMGIKDF_03373 8.4e-243 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HIMGIKDF_03374 1.3e-298 gpmI 5.4.2.12 G Catalyzes the interconversion of 2-phosphoglycerate and
HIMGIKDF_03375 4.3e-138 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HIMGIKDF_03376 1e-218 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HIMGIKDF_03377 6.2e-185 gapA 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HIMGIKDF_03378 6.3e-185 cggR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIMGIKDF_03379 1.6e-252 araE EGP Major facilitator Superfamily
HIMGIKDF_03380 5.5e-203 araR K transcriptional
HIMGIKDF_03381 1.5e-191 yvbT C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_03382 3.9e-159 yvbU K Transcriptional regulator
HIMGIKDF_03383 8.5e-157 yvbV EG EamA-like transporter family
HIMGIKDF_03384 2.8e-241 yvbW E COG1113 Gamma-aminobutyrate permease and related permeases
HIMGIKDF_03385 4.3e-197 yvbX S Glycosyl hydrolase
HIMGIKDF_03386 2.3e-133 lutC S Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIMGIKDF_03387 1.2e-274 lutB C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate
HIMGIKDF_03388 1.5e-137 lutA C Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source
HIMGIKDF_03389 2.6e-106 desR T COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_03390 8.9e-201 desK 2.7.13.3 T Histidine kinase
HIMGIKDF_03391 6.2e-134 yvfS V COG0842 ABC-type multidrug transport system, permease component
HIMGIKDF_03392 3e-162 yvfR V COG1131 ABC-type multidrug transport system, ATPase component
HIMGIKDF_03393 2.6e-157 rsbQ S Alpha/beta hydrolase family
HIMGIKDF_03394 1.4e-199 rsbU 3.1.3.3 T response regulator
HIMGIKDF_03395 2.6e-252 galA 3.2.1.89 G arabinogalactan
HIMGIKDF_03396 1e-66 lacA 3.2.1.23 G beta-galactosidase
HIMGIKDF_03397 2.7e-134 S Rhabdovirus spike glycoprotein
HIMGIKDF_03398 2.8e-134 ksgA 2.1.1.182, 2.1.1.184 J Ribosomal RNA adenine dimethylase
HIMGIKDF_03399 7.1e-11
HIMGIKDF_03400 5.6e-97 lacA 3.2.1.23 G beta-galactosidase
HIMGIKDF_03401 3.2e-150 ganQ P transport
HIMGIKDF_03402 1.3e-232 malC P COG1175 ABC-type sugar transport systems, permease components
HIMGIKDF_03403 2.9e-232 cycB G COG2182 Maltose-binding periplasmic proteins domains
HIMGIKDF_03404 1.8e-184 lacR K Transcriptional regulator
HIMGIKDF_03405 6.6e-111 yvfI K COG2186 Transcriptional regulators
HIMGIKDF_03406 1.4e-309 yvfH C L-lactate permease
HIMGIKDF_03407 6.5e-243 rpoN K COG1508 DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog
HIMGIKDF_03408 1e-31 yvfG S YvfG protein
HIMGIKDF_03409 5.8e-188 yvfF GM Exopolysaccharide biosynthesis protein
HIMGIKDF_03410 1.2e-224 epsN 2.6.1.102 E Belongs to the DegT DnrJ EryC1 family
HIMGIKDF_03411 2.2e-58 epsM GM COG0110 Acetyltransferase (isoleucine patch superfamily)
HIMGIKDF_03412 2.6e-109 epsL M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIMGIKDF_03413 8.9e-260 pglK S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_03414 1.9e-197 epsJ GT2 S COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMGIKDF_03415 3.6e-207 epsI GM pyruvyl transferase
HIMGIKDF_03416 3.6e-196 epsH GT2 S Glycosyltransferase like family 2
HIMGIKDF_03417 4.8e-207 epsG S EpsG family
HIMGIKDF_03418 5.3e-220 epsF GT4 M Glycosyl transferases group 1
HIMGIKDF_03419 4.1e-158 epsE GT2 M COG0463 Glycosyltransferases involved in cell wall biogenesis
HIMGIKDF_03420 2e-224 epsD GT4 M Glycosyl transferase 4-like
HIMGIKDF_03421 0.0 pglF 4.2.1.115, 4.2.1.135, 4.2.1.46 GM Polysaccharide biosynthesis protein
HIMGIKDF_03422 1e-114 epsB 2.7.10.2 D COG0489 ATPases involved in chromosome partitioning
HIMGIKDF_03423 4e-122 ywqC M biosynthesis protein
HIMGIKDF_03424 5.7e-77 slr K transcriptional
HIMGIKDF_03425 4.8e-287 pnbA CE10 I Belongs to the type-B carboxylesterase lipase family
HIMGIKDF_03427 4.6e-93 padC Q Phenolic acid decarboxylase
HIMGIKDF_03428 1.3e-48 MA20_18690 S Protein of unknown function (DUF3237)
HIMGIKDF_03429 3.1e-127 racX 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HIMGIKDF_03430 9.6e-266 pbpE V Beta-lactamase
HIMGIKDF_03431 1.2e-274 sacB 2.4.1.10 GH68 M levansucrase activity
HIMGIKDF_03432 0.0 levB 3.2.1.26, 3.2.1.64, 3.2.1.65, 3.2.1.80 GH32 G Belongs to the glycosyl hydrolase 32 family
HIMGIKDF_03433 1.8e-295 yveA E amino acid
HIMGIKDF_03434 2.6e-106 yvdT K Transcriptional regulator
HIMGIKDF_03435 6.7e-51 ykkC P Small Multidrug Resistance protein
HIMGIKDF_03436 4.1e-50 sugE P Small Multidrug Resistance protein
HIMGIKDF_03437 2.2e-93 yvdQ S Protein of unknown function (DUF3231)
HIMGIKDF_03438 8.4e-270 ygaK C COG0277 FAD FMN-containing dehydrogenases
HIMGIKDF_03439 1.5e-183 S Patatin-like phospholipase
HIMGIKDF_03441 1.2e-103 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HIMGIKDF_03442 1.3e-122 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S Haloacid dehalogenase-like hydrolase
HIMGIKDF_03443 0.0 malL 3.2.1.10 GH13 G COG0366 Glycosidases
HIMGIKDF_03444 0.0 yvdK 2.4.1.8 GH65 G Glycoside hydrolase, family 65
HIMGIKDF_03445 1.2e-158 malA S Protein of unknown function (DUF1189)
HIMGIKDF_03446 7.8e-149 malD P transport
HIMGIKDF_03447 5.3e-245 malC P COG1175 ABC-type sugar transport systems, permease components
HIMGIKDF_03448 1.3e-235 mdxE G COG2182 Maltose-binding periplasmic proteins domains
HIMGIKDF_03449 0.0 nplT 3.2.1.133, 3.2.1.135, 3.2.1.54 GH13 G Alpha amylase, N-terminal ig-like domain
HIMGIKDF_03450 3.6e-174 yvdE K Transcriptional regulator
HIMGIKDF_03451 3.3e-106 yvdD 3.2.2.10 S Belongs to the LOG family
HIMGIKDF_03452 6.8e-53 yvdC S MazG nucleotide pyrophosphohydrolase domain
HIMGIKDF_03453 2.1e-288 sulP P COG0659 Sulfate permease and related transporters (MFS superfamily)
HIMGIKDF_03454 5.7e-106 ytiB 4.2.1.1 P Reversible hydration of carbon dioxide
HIMGIKDF_03455 1.3e-184 ghrB 1.1.1.215, 1.1.1.26, 1.1.1.43, 1.1.1.79, 1.1.1.81 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HIMGIKDF_03456 0.0 yxdM V ABC transporter (permease)
HIMGIKDF_03457 5.6e-141 yvcR V ABC transporter, ATP-binding protein
HIMGIKDF_03458 2.3e-198 yvcQ 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HIMGIKDF_03459 3.9e-133 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_03460 1.8e-33
HIMGIKDF_03461 8.6e-147 nhoA 2.3.1.118 Q Belongs to the arylamine N-acetyltransferase family
HIMGIKDF_03462 1.6e-36 crh G Phosphocarrier protein Chr
HIMGIKDF_03463 1.4e-170 whiA K May be required for sporulation
HIMGIKDF_03464 7.3e-178 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HIMGIKDF_03465 5.7e-166 rapZ S Displays ATPase and GTPase activities
HIMGIKDF_03466 1.8e-89 yvcI 3.6.1.55 F COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes
HIMGIKDF_03467 1.4e-175 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HIMGIKDF_03468 1.4e-102 usp CBM50 M protein conserved in bacteria
HIMGIKDF_03469 2.4e-278 S COG0457 FOG TPR repeat
HIMGIKDF_03470 0.0 msbA2 3.6.3.44 V ABC transporter
HIMGIKDF_03472 0.0
HIMGIKDF_03473 4.6e-121
HIMGIKDF_03474 8e-114 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E belongs to the PRA-CH family
HIMGIKDF_03475 2.8e-137 hisF E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
HIMGIKDF_03476 3.1e-133 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HIMGIKDF_03477 1.7e-116 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HIMGIKDF_03478 2.1e-108 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
HIMGIKDF_03479 6.6e-232 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HIMGIKDF_03480 1.5e-115 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
HIMGIKDF_03481 4.8e-221 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HIMGIKDF_03482 4.5e-140 yvpB NU protein conserved in bacteria
HIMGIKDF_03483 5.5e-121 hrpW 4.2.2.10, 4.2.2.2 G Pectate lyase
HIMGIKDF_03484 3e-82 yvoF S COG0110 Acetyltransferase (isoleucine patch superfamily)
HIMGIKDF_03485 1.3e-119 ppaX 3.1.3.18, 3.6.1.1 S Hydrolyzes pyrophosphate formed during P-Ser-HPr dephosphorylation by HPrK P. Might play a role in controlling the intracellular pyrophosphate pool
HIMGIKDF_03486 1.5e-164 yvoD P COG0370 Fe2 transport system protein B
HIMGIKDF_03487 4.9e-148 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HIMGIKDF_03488 1.7e-168 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Also phosphorylates dephosphorylates the HPr-like catabolite repression protein crh on a specific serine residue. Therefore, by controlling the phosphorylation state of HPr and crh, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HIMGIKDF_03489 6.8e-223 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HIMGIKDF_03490 8.9e-133 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HIMGIKDF_03491 3.6e-134 yvoA K transcriptional
HIMGIKDF_03492 0.0 yvnB 3.1.4.53 Q Calcineurin-like phosphoesterase
HIMGIKDF_03493 8.5e-84 adcR K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_03494 8.2e-232 cypX 1.14.15.13 C Cytochrome P450
HIMGIKDF_03495 1.6e-137 yvmC 2.3.2.22 S Involved in the biosynthesis of pulcherrimin, a red extracellular pigment. It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP- independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can also incorporate various nonpolar residues, such as L- phenylalanine, L-leucine and methionine, into cyclodipeptides
HIMGIKDF_03496 3e-87 yvmB K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_03497 2.7e-203 yvmA EGP Major facilitator Superfamily
HIMGIKDF_03498 1.2e-50 yvlD S Membrane
HIMGIKDF_03499 2.6e-26 pspB KT PspC domain
HIMGIKDF_03500 3.4e-168 yvlB S Putative adhesin
HIMGIKDF_03501 8e-49 yvlA
HIMGIKDF_03502 6.7e-34 yvkN
HIMGIKDF_03503 2.9e-79 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIMGIKDF_03504 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HIMGIKDF_03505 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HIMGIKDF_03506 1.2e-30 csbA S protein conserved in bacteria
HIMGIKDF_03507 0.0 yvkC 2.7.9.2 GT Phosphotransferase
HIMGIKDF_03508 7e-101 yvkB K Transcriptional regulator
HIMGIKDF_03509 7.9e-228 yvkA EGP Major facilitator Superfamily
HIMGIKDF_03510 4.9e-221 minJ O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMGIKDF_03511 1e-54 swrA S Swarming motility protein
HIMGIKDF_03512 6.9e-270 ctpB 3.4.21.102 M Belongs to the peptidase S41A family
HIMGIKDF_03513 1.6e-155 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
HIMGIKDF_03514 1.6e-123 ftsE D cell division ATP-binding protein FtsE
HIMGIKDF_03515 5.3e-56 cccB C COG2010 Cytochrome c, mono- and diheme variants
HIMGIKDF_03516 5.5e-142 yvjA S Uncharacterized protein conserved in bacteria (DUF2179)
HIMGIKDF_03517 6.1e-185 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HIMGIKDF_03518 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HIMGIKDF_03519 2.2e-102 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HIMGIKDF_03520 2.8e-66
HIMGIKDF_03521 1.9e-08 fliT S bacterial-type flagellum organization
HIMGIKDF_03522 2.9e-69 fliS N flagellar protein FliS
HIMGIKDF_03523 1.3e-266 fliD N morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
HIMGIKDF_03524 6.1e-57 flaG N flagellar protein FlaG
HIMGIKDF_03525 1.9e-156 fliC N Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HIMGIKDF_03526 2e-30 csrA T Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HIMGIKDF_03527 2.7e-73 fliW S Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
HIMGIKDF_03528 2.6e-50 yviE
HIMGIKDF_03529 1.1e-156 flgL N Belongs to the bacterial flagellin family
HIMGIKDF_03530 1.2e-264 flgK N flagellar hook-associated protein
HIMGIKDF_03531 2.4e-78 flgN NOU FlgN protein
HIMGIKDF_03532 4.2e-40 flgM KNU Negative regulator of flagellin synthesis
HIMGIKDF_03533 7e-74 yvyF S flagellar protein
HIMGIKDF_03534 2.7e-129 comFC S Phosphoribosyl transferase domain
HIMGIKDF_03535 5.7e-46 comFB S Late competence development protein ComFB
HIMGIKDF_03536 5.6e-269 comFA L COG4098 Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
HIMGIKDF_03537 7.3e-155 degV S protein conserved in bacteria
HIMGIKDF_03538 2e-126 degU KT COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
HIMGIKDF_03539 5.1e-183 degS 2.7.13.3 T Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase
HIMGIKDF_03540 2e-120 yvyE 3.4.13.9 S Domain of unknown function (DUF1949)
HIMGIKDF_03541 6e-163 yvhJ K Transcriptional regulator
HIMGIKDF_03542 2.6e-181 tagO 2.7.8.33, 2.7.8.35 M COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase
HIMGIKDF_03543 4.4e-238 tuaH M Teichuronic acid biosynthesis glycosyltransferase tuaH
HIMGIKDF_03544 2.1e-145 tuaG GT2 M Glycosyltransferase like family 2
HIMGIKDF_03545 6e-115 tuaF M protein involved in exopolysaccharide biosynthesis
HIMGIKDF_03546 1.7e-263 tuaE M Teichuronic acid biosynthesis protein
HIMGIKDF_03547 2.4e-259 tuaD 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIMGIKDF_03548 7.4e-222 tuaC 2.4.1.21, 3.2.1.1 GH13,GT4,GT5 GM Teichuronic acid
HIMGIKDF_03549 3.3e-248 wzxC S COG2244 Membrane protein involved in the export of O-antigen and teichoic acid
HIMGIKDF_03550 2.7e-78 tuaA M COG2148 Sugar transferases involved in lipopolysaccharide synthesis
HIMGIKDF_03551 3e-268 lytC 3.5.1.28 M n-acetylmuramoyl-L-alanine amidase
HIMGIKDF_03552 0.0 lytB 3.5.1.28 D Stage II sporulation protein
HIMGIKDF_03553 6e-38
HIMGIKDF_03554 6.1e-163 lytR K May catalyze the final step in cell wall teichoic acid biosynthesis, the transfer of the anionic cell wall polymers (APs) from their lipid-linked precursor to the cell wall peptidoglycan (PG)
HIMGIKDF_03555 8.2e-218 mnaA 5.1.3.14 M Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HIMGIKDF_03556 9e-164 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMGIKDF_03557 0.0 ggaB GT2 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HIMGIKDF_03558 8.1e-257 ggaA M Glycosyltransferase like family 2
HIMGIKDF_03560 1.6e-100 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HIMGIKDF_03561 1.8e-279 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HIMGIKDF_03562 1.1e-150 tagG GM Transport permease protein
HIMGIKDF_03563 0.0 tagF 2.7.8.12 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIMGIKDF_03564 0.0 tagE 2.4.1.52 GT4 M Glycosyl transferase 1 domain A
HIMGIKDF_03565 5.7e-70 tagD 2.7.7.15, 2.7.7.39 IM Cytidylyltransferase
HIMGIKDF_03566 1.8e-144 tagA 2.4.1.187 GT26 M Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HIMGIKDF_03567 5e-215 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
HIMGIKDF_03568 1.2e-260
HIMGIKDF_03569 7.2e-217 atl 3.2.1.96, 3.5.1.28 GH73 G Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HIMGIKDF_03570 7.1e-191 pmi 5.3.1.8 G mannose-6-phosphate isomerase
HIMGIKDF_03571 3.5e-266 gerBA EG Spore germination protein
HIMGIKDF_03572 7.5e-200 gerBB E Spore germination protein
HIMGIKDF_03573 7.6e-216 gerAC S Spore germination protein
HIMGIKDF_03574 1.9e-248 ywtG EGP Major facilitator Superfamily
HIMGIKDF_03575 8.4e-171 ywtF K Transcriptional regulator
HIMGIKDF_03576 7e-161 ywtE 3.1.3.104 S hydrolases of the HAD superfamily
HIMGIKDF_03577 5.4e-240 pgdS CBM50 M COG0791 Cell wall-associated hydrolases (invasion-associated proteins)
HIMGIKDF_03578 3.6e-21 ywtC
HIMGIKDF_03579 1.7e-218 capA M enzyme of poly-gamma-glutamate biosynthesis (capsule formation)
HIMGIKDF_03580 8.6e-70 pgsC S biosynthesis protein
HIMGIKDF_03581 6.1e-224 murD 6.3.2.9 M COG0769 UDP-N-acetylmuramyl tripeptide synthase
HIMGIKDF_03582 1.5e-180 rbsR K transcriptional
HIMGIKDF_03583 2.9e-162 rbsK 2.7.1.15, 2.7.1.4 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HIMGIKDF_03584 2.8e-64 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HIMGIKDF_03585 2.3e-276 rbsA 3.6.3.17 G Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system
HIMGIKDF_03586 1.4e-154 rbsC G Belongs to the binding-protein-dependent transport system permease family
HIMGIKDF_03587 4.4e-161 rbsB G COG1879 ABC-type sugar transport system, periplasmic component
HIMGIKDF_03588 4.6e-94 batE T Sh3 type 3 domain protein
HIMGIKDF_03589 3.6e-48 ywsA S Protein of unknown function (DUF3892)
HIMGIKDF_03590 1.5e-97 ywrO S NADPH-quinone reductase (modulator of drug activity B)
HIMGIKDF_03591 1.3e-145 budA 4.1.1.5 H Alpha-acetolactate decarboxylase
HIMGIKDF_03592 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HIMGIKDF_03593 1.1e-169 alsR K LysR substrate binding domain
HIMGIKDF_03594 1.9e-220 ywrK P Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HIMGIKDF_03595 7.5e-126 ywrJ
HIMGIKDF_03596 7.6e-131 cotB
HIMGIKDF_03597 1.2e-210 cotH M Spore Coat
HIMGIKDF_03598 3.7e-12
HIMGIKDF_03599 8.1e-111 ywrF S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HIMGIKDF_03600 2.9e-54 S Domain of unknown function (DUF4181)
HIMGIKDF_03601 9.6e-310 ggt 2.3.2.2, 3.4.19.13 E gamma-glutamyltransferase
HIMGIKDF_03602 2.1e-82 ywrC K Transcriptional regulator
HIMGIKDF_03603 2.4e-104 ywrB P Chromate transporter
HIMGIKDF_03604 6.9e-90 ywrA P COG2059 Chromate transport protein ChrA
HIMGIKDF_03606 2.7e-102 ywqN S NAD(P)H-dependent
HIMGIKDF_03607 2.9e-162 K Transcriptional regulator
HIMGIKDF_03608 4.5e-137 nfi 3.1.21.7 L DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA
HIMGIKDF_03609 1.7e-52 S MORN repeat variant
HIMGIKDF_03610 0.0 ywqJ L nucleic acid phosphodiester bond hydrolysis
HIMGIKDF_03611 1.3e-38 ywqI S Family of unknown function (DUF5344)
HIMGIKDF_03612 3.3e-15 S Domain of unknown function (DUF5082)
HIMGIKDF_03613 3.4e-154 ywqG S Domain of unknown function (DUF1963)
HIMGIKDF_03614 3e-248 ugd 1.1.1.22 M Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HIMGIKDF_03615 1.4e-141 ywqE 3.1.3.48 GM COG4464 Capsular polysaccharide biosynthesis protein
HIMGIKDF_03616 1.1e-119 ywqD 2.7.10.1 D COG0489 ATPases involved in chromosome partitioning
HIMGIKDF_03617 2e-116 ywqC M biosynthesis protein
HIMGIKDF_03618 1.2e-17
HIMGIKDF_03619 3.8e-309 ywqB S SWIM zinc finger
HIMGIKDF_03620 0.0 ywqA L COG0553 Superfamily II DNA RNA helicases, SNF2 family
HIMGIKDF_03621 3.6e-157 ywpJ 3.1.3.104 S hydrolases of the HAD superfamily
HIMGIKDF_03622 8.8e-139 glcR K COG1349 Transcriptional regulators of sugar metabolism
HIMGIKDF_03623 9.8e-58 ssbB L Single-stranded DNA-binding protein
HIMGIKDF_03624 1.3e-66 ywpG
HIMGIKDF_03625 1.1e-66 ywpF S YwpF-like protein
HIMGIKDF_03626 8e-51 srtA 3.4.22.70 M Sortase family
HIMGIKDF_03627 1.9e-153 ywpD T Histidine kinase
HIMGIKDF_03628 1.5e-54 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HIMGIKDF_03629 4.6e-82 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HIMGIKDF_03630 2.1e-199 S aspartate phosphatase
HIMGIKDF_03631 1.5e-141 flhP N flagellar basal body
HIMGIKDF_03632 6.9e-126 flhO N flagellar basal body
HIMGIKDF_03633 3.5e-180 mbl D Rod shape-determining protein
HIMGIKDF_03634 3e-44 spoIIID K Stage III sporulation protein D
HIMGIKDF_03635 2.1e-70 ywoH K COG1846 Transcriptional regulators
HIMGIKDF_03636 2.7e-211 ywoG EGP Major facilitator Superfamily
HIMGIKDF_03637 1.2e-231 ywoF P Right handed beta helix region
HIMGIKDF_03638 3e-281 ybbW FH COG1953 Cytosine uracil thiamine allantoin permeases
HIMGIKDF_03639 4.4e-242 ywoD EGP Major facilitator superfamily
HIMGIKDF_03640 4e-104 phzA Q Isochorismatase family
HIMGIKDF_03641 1.2e-77
HIMGIKDF_03642 2.5e-225 amt P Ammonium transporter
HIMGIKDF_03643 1.6e-58 nrgB K Belongs to the P(II) protein family
HIMGIKDF_03644 3.4e-103 bcrC 3.6.1.27 I COG0671 Membrane-associated phospholipid phosphatase
HIMGIKDF_03645 3.5e-73 ywnJ S VanZ like family
HIMGIKDF_03646 5.5e-126 spoIIQ M COG0739 Membrane proteins related to metalloendopeptidases
HIMGIKDF_03647 6.4e-90 ywnH 2.3.1.183 M COG1247 Sortase and related acyltransferases
HIMGIKDF_03648 2.7e-14 ywnC S Family of unknown function (DUF5362)
HIMGIKDF_03649 2.2e-70 ywnF S Family of unknown function (DUF5392)
HIMGIKDF_03650 1.2e-277 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMGIKDF_03651 4.1e-144 mta K transcriptional
HIMGIKDF_03652 2.6e-59 ywnC S Family of unknown function (DUF5362)
HIMGIKDF_03653 1.6e-114 ywnB S NAD(P)H-binding
HIMGIKDF_03654 1.7e-64 ywnA K Transcriptional regulator
HIMGIKDF_03655 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
HIMGIKDF_03656 5.9e-64 ureB 3.5.1.5 E Belongs to the urease beta subunit family
HIMGIKDF_03657 6.3e-51 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
HIMGIKDF_03659 3.8e-11 csbD K CsbD-like
HIMGIKDF_03660 3e-84 ywmF S Peptidase M50
HIMGIKDF_03661 1.3e-103 S response regulator aspartate phosphatase
HIMGIKDF_03662 7e-192 moaA 4.1.99.22, 4.6.1.17 H Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HIMGIKDF_03663 2.6e-146 fdhD C Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HIMGIKDF_03665 7.2e-121 ywmD S protein containing a von Willebrand factor type A (vWA) domain
HIMGIKDF_03666 1.7e-122 ywmC S protein containing a von Willebrand factor type A (vWA) domain
HIMGIKDF_03667 2e-178 spoIID D Stage II sporulation protein D
HIMGIKDF_03668 1.2e-241 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMGIKDF_03669 1.6e-134 ywmB S TATA-box binding
HIMGIKDF_03670 1.3e-32 ywzB S membrane
HIMGIKDF_03671 4.3e-88 ywmA
HIMGIKDF_03672 5.9e-54 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HIMGIKDF_03673 1.2e-266 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HIMGIKDF_03674 1.1e-150 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HIMGIKDF_03675 6.9e-281 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HIMGIKDF_03676 1.1e-90 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMGIKDF_03677 3.8e-45 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HIMGIKDF_03678 1.6e-26 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HIMGIKDF_03679 4.6e-129 atpB C it plays a direct role in the translocation of protons across the membrane
HIMGIKDF_03680 2.5e-62 atpI S ATP synthase
HIMGIKDF_03681 4.7e-114 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HIMGIKDF_03682 2.1e-238 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HIMGIKDF_03683 7.2e-95 ywlG S Belongs to the UPF0340 family
HIMGIKDF_03684 1.7e-81 rpiB 5.3.1.6 G Ribose 5-phosphate isomerase
HIMGIKDF_03685 1.7e-78 ywlE 3.1.3.48, 3.9.1.2, 5.3.1.6 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HIMGIKDF_03686 1.7e-91 mntP P Probably functions as a manganese efflux pump
HIMGIKDF_03687 1.2e-196 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HIMGIKDF_03688 1.2e-76 ywlB 1.20.4.1, 2.3.1.1 E Belongs to the acetyltransferase family. ArgA subfamily
HIMGIKDF_03689 6.1e-112 spoIIR S stage II sporulation protein R
HIMGIKDF_03690 3.4e-56 ywlA S Uncharacterised protein family (UPF0715)
HIMGIKDF_03692 2.3e-159 prmC 2.1.1.297 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HIMGIKDF_03693 9.5e-192 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HIMGIKDF_03694 8.2e-69 yaeR E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_03695 1.7e-91 racA K Required for the formation of axial filaments and for anchoring the origin regions at the cell poles in sporulating cells, thus ensuring proper chromosome segregation in the prespore. Binds in a dispersed manner throughout the chromosome but preferentially to sites clustered in the origin portion of the chromosome, causing condensation of the chromosome and its remodeling into an elongated, anchored structure
HIMGIKDF_03696 8.6e-160 ywkB S Membrane transport protein
HIMGIKDF_03697 0.0 sfcA 1.1.1.38 C malic enzyme
HIMGIKDF_03698 2.4e-104 tdk 2.7.1.21 F thymidine kinase
HIMGIKDF_03699 1.1e-32 rpmE J Binds the 23S rRNA
HIMGIKDF_03700 2.8e-238 rho K Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
HIMGIKDF_03701 1.9e-175 glpX 3.1.3.11, 3.1.3.37 G fructose-1,6-bisphosphatase
HIMGIKDF_03702 8.6e-240 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HIMGIKDF_03703 1.5e-112 tal 2.2.1.2 G Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HIMGIKDF_03704 7.2e-158 fbaA 4.1.2.13, 4.1.2.29 G Aldolase
HIMGIKDF_03705 1.1e-62 spo0F T COG0784 FOG CheY-like receiver
HIMGIKDF_03706 2.4e-92 ywjG S Domain of unknown function (DUF2529)
HIMGIKDF_03707 0.0 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HIMGIKDF_03708 1.5e-49 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HIMGIKDF_03709 2.6e-211 acdA 1.3.8.1, 1.3.8.7 I acyl-CoA dehydrogenase
HIMGIKDF_03710 0.0 fadF C COG0247 Fe-S oxidoreductase
HIMGIKDF_03711 2.3e-223 clsB I Belongs to the phospholipase D family. Cardiolipin synthase subfamily
HIMGIKDF_03712 6.6e-184 uvsE L Component in a DNA repair pathway. Removal of UV-light damaged nucleotides. Recognizes pyrimidine dimers and cleave a phosphodiester bond immediately 5' to the lesion
HIMGIKDF_03713 2.7e-42 ywjC
HIMGIKDF_03714 4.8e-96 ywjB H RibD C-terminal domain
HIMGIKDF_03715 0.0 ywjA V ABC transporter
HIMGIKDF_03716 6.4e-287 ywiE I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HIMGIKDF_03717 1.8e-124 narI 1.7.5.1 C nitrate reductase, gamma
HIMGIKDF_03718 2.4e-98 narJ 1.7.5.1 C nitrate reductase
HIMGIKDF_03719 1e-297 narH 1.7.5.1 C Nitrate reductase, beta
HIMGIKDF_03720 0.0 narG 1.7.5.1 C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMGIKDF_03721 7e-86 arfM T cyclic nucleotide binding
HIMGIKDF_03722 4.3e-140 ywiC S YwiC-like protein
HIMGIKDF_03723 5.3e-130 fnr K helix_turn_helix, cAMP Regulatory protein
HIMGIKDF_03724 9.8e-214 narK P COG2223 Nitrate nitrite transporter
HIMGIKDF_03725 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HIMGIKDF_03726 4.7e-73 ywiB S protein conserved in bacteria
HIMGIKDF_03727 1e-07 S Bacteriocin subtilosin A
HIMGIKDF_03728 2.6e-271 C Fe-S oxidoreductases
HIMGIKDF_03730 3.3e-132 cbiO V ABC transporter
HIMGIKDF_03731 3.1e-237 mgtA 3.6.3.2 P ATPase, P-type transporting, HAD superfamily, subfamily IC
HIMGIKDF_03732 2.7e-219 2.7.1.26, 2.7.7.2 L Peptidase, M16
HIMGIKDF_03733 1.2e-249 L Peptidase, M16
HIMGIKDF_03735 2.9e-249 ywhL CO amine dehydrogenase activity
HIMGIKDF_03736 2.5e-205 ywhK CO amine dehydrogenase activity
HIMGIKDF_03737 2.3e-79 S aspartate phosphatase
HIMGIKDF_03739 1e-84 ywhH S Aminoacyl-tRNA editing domain
HIMGIKDF_03740 9.2e-169 speB 3.5.3.11 E Belongs to the arginase family
HIMGIKDF_03741 1.4e-158 speE 2.5.1.16 E Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HIMGIKDF_03742 0.0 pbpG 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HIMGIKDF_03743 5.2e-95 ywhD S YwhD family
HIMGIKDF_03744 5.1e-119 ywhC S Peptidase family M50
HIMGIKDF_03745 2.7e-25 dmpI 5.3.2.6 G 4-oxalocrotonate tautomerase
HIMGIKDF_03746 3.3e-71 ywhA K Transcriptional regulator
HIMGIKDF_03747 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HIMGIKDF_03749 2.6e-242 mmr U Major Facilitator Superfamily
HIMGIKDF_03750 2.8e-79 yffB K Transcriptional regulator
HIMGIKDF_03751 5.4e-89 ywgA 2.1.1.72, 3.1.21.3
HIMGIKDF_03752 1.8e-256 ywfO S COG1078 HD superfamily phosphohydrolases
HIMGIKDF_03753 3.1e-36 ywzC S Belongs to the UPF0741 family
HIMGIKDF_03754 1.6e-111 rsfA_1
HIMGIKDF_03755 5.2e-159 ywfM EG EamA-like transporter family
HIMGIKDF_03756 6.6e-156 lipL 2.3.1.200, 2.3.1.204 H Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes
HIMGIKDF_03757 9.2e-164 cysL K Transcriptional regulator
HIMGIKDF_03758 6.6e-176 pta 2.3.1.19, 2.3.1.8, 3.6.3.21 C In Salmonella this enzyme is required for ethanolamine catabolism
HIMGIKDF_03759 1.1e-146 ywfI C May function as heme-dependent peroxidase
HIMGIKDF_03760 4e-139 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_03761 2.7e-235 ywfG 2.6.1.83 E Aminotransferase class I and II
HIMGIKDF_03762 2.9e-210 bacE EGP Major facilitator Superfamily
HIMGIKDF_03763 3.6e-271 purD 6.3.2.49, 6.3.4.13 F Part of the bacABCDEFG operon responsible for the biosynthesis of bacilysin, an irreversible inactivator of the glutaminase domain of glucosamine synthetase. Catalyzes the formation of alpha-dipeptides from various L-amino acids in the presence of ATP. In vivo catalyzes the ligation of L-alanine and L-anticapsin (epoxycyclohexanonyl-Ala) to produce the final bacilysin antibiotic (L-Ala-L-4S-cyclohexenonyl-Ala dipeptide)
HIMGIKDF_03764 1.3e-139 IQ COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HIMGIKDF_03765 1.3e-136 bacB 5.3.3.19, 5.4.99.5 S Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacB catalyzes the allylic isomerization of the
HIMGIKDF_03766 8.6e-113 pheA 1.1.1.3, 1.3.1.12, 4.1.1.100, 4.2.1.51, 5.4.99.5 E Part of the bacABCDEF operon responsible for the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. Bacilysin is an irreversible inactivator of the glutaminase domain of glucosamine synthetase. BacA is an unusual prephenate decarboxylase that avoids the typical aromatization of the cyclohexadienol ring of prephenate. BacA catalyzes the protonation of prephenate (1-carboxy-4-hydroxy-alpha-oxo-2,5-cyclohexadiene-1- propanoic acid) at C6 position, followed by a decarboxylation to produce the endocyclic-delta(4),delta(8)-7R-dihydro- hydroxyphenylpyruvate (en-H2HPP). En-H2HPP is able to undergo a slow nonenzymatic isomerization to produce the exocyclic- delta(3),delta(5)-dihydro-hydroxyphenylpyruvate (ex-H2HPP). BacA isomerizes only the pro-R double bond in prephenate
HIMGIKDF_03767 4.6e-206 ywfA EGP Major facilitator Superfamily
HIMGIKDF_03768 5.1e-251 lysP E amino acid
HIMGIKDF_03769 0.0 rocB E arginine degradation protein
HIMGIKDF_03770 1.4e-297 putA 1.2.1.88, 1.5.5.2 C Belongs to the aldehyde dehydrogenase family. RocA subfamily
HIMGIKDF_03771 7.5e-244 rocG 1.4.1.2, 1.4.1.3 E Belongs to the Glu Leu Phe Val dehydrogenases family
HIMGIKDF_03772 1.8e-78
HIMGIKDF_03773 3.5e-87 spsL 5.1.3.13 M Spore Coat
HIMGIKDF_03774 5.3e-161 spsK 1.1.1.133 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
HIMGIKDF_03775 1e-181 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HIMGIKDF_03776 1.9e-138 spsI 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HIMGIKDF_03777 1.7e-190 spsG M Spore Coat
HIMGIKDF_03778 9.7e-132 spsF M Spore Coat
HIMGIKDF_03779 3.2e-214 spsE 2.5.1.56 M acid synthase
HIMGIKDF_03780 4e-164 spsD 2.3.1.210 K Spore Coat
HIMGIKDF_03781 1.6e-224 spsC E Belongs to the DegT DnrJ EryC1 family
HIMGIKDF_03782 1.5e-269 spsB M Capsule polysaccharide biosynthesis protein
HIMGIKDF_03783 2.8e-145 spsA M Spore Coat
HIMGIKDF_03784 4.8e-75 gerQ S Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA
HIMGIKDF_03785 4.3e-59 ywdK S small membrane protein
HIMGIKDF_03786 1.3e-238 ywdJ F Xanthine uracil
HIMGIKDF_03787 7.7e-49 ywdI S Family of unknown function (DUF5327)
HIMGIKDF_03788 5.9e-263 ywdH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HIMGIKDF_03789 5e-130 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HIMGIKDF_03790 1.1e-152 ywdF GT2,GT4 S Glycosyltransferase like family 2
HIMGIKDF_03792 1.4e-113 ywdD
HIMGIKDF_03793 1.3e-57 pex K Transcriptional regulator PadR-like family
HIMGIKDF_03794 9.3e-147 thiD 2.5.1.3, 2.7.1.35, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HIMGIKDF_03795 2e-28 ywdA
HIMGIKDF_03796 9.5e-296 scrB 3.2.1.26, 3.2.1.65, 3.2.1.80 GH32 G invertase
HIMGIKDF_03797 3.9e-254 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_03798 1e-139 focA P Formate/nitrite transporter
HIMGIKDF_03799 2.4e-150 sacT K transcriptional antiterminator
HIMGIKDF_03801 0.0 vpr O Belongs to the peptidase S8 family
HIMGIKDF_03802 5.1e-187 ywcH C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_03803 7.2e-138 nfrA 1.5.1.38, 1.5.1.39 C Oxidoreductase
HIMGIKDF_03804 2.9e-202 rodA D Belongs to the SEDS family
HIMGIKDF_03805 6e-39 ywcE S Required for proper spore morphogenesis. Important for spore germination
HIMGIKDF_03806 2.6e-64 qoxD 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HIMGIKDF_03807 1.2e-111 qoxC 1.10.3.12, 1.9.3.1 C quinol oxidase, subunit
HIMGIKDF_03808 0.0 qoxB 1.10.3.12, 1.9.3.1 C Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HIMGIKDF_03809 2.1e-177 cyoA 1.10.3.10, 1.10.3.12 C Catalyzes quinol oxidation with the concomitant reduction of oxygen to water. Subunit II transfers the electrons from a quinol to the binuclear center of the catalytic subunit I
HIMGIKDF_03810 1e-35 ywzA S membrane
HIMGIKDF_03811 3.7e-306 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HIMGIKDF_03812 6.2e-229 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HIMGIKDF_03813 9.5e-60 gtcA S GtrA-like protein
HIMGIKDF_03814 2.2e-122 ywcC K transcriptional regulator
HIMGIKDF_03816 9.8e-49 ywcB S Protein of unknown function, DUF485
HIMGIKDF_03817 1.4e-268 ywcA S Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HIMGIKDF_03818 1.9e-112 ywbO Q dithiol-disulfide isomerase involved in polyketide biosynthesis
HIMGIKDF_03819 2.6e-225 ywbN P Dyp-type peroxidase family protein
HIMGIKDF_03820 2e-187 ycdO P periplasmic lipoprotein involved in iron transport
HIMGIKDF_03821 8.2e-255 P COG0672 High-affinity Fe2 Pb2 permease
HIMGIKDF_03822 4.1e-116 thiE 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HIMGIKDF_03823 2.8e-143 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HIMGIKDF_03824 4.3e-153 ywbI K Transcriptional regulator
HIMGIKDF_03825 6.5e-58 ywbH S Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. When a cell is stressed by the addition of antibiotics or by other factors in the environment, CidA possibly oligomerizes within the bacterial cell membrane, creating lesions that disrupt the proton motive force, which in turn results in loss of cell viability. These lesions are also hypothesized to regulate the subsequent cell lysis by either allowing the murein hydrolases access to the cell wall substrate and or regulating their activity by a
HIMGIKDF_03826 2.3e-111 ywbG M effector of murein hydrolase
HIMGIKDF_03827 1.9e-209 ywbF EGP Major facilitator Superfamily
HIMGIKDF_03828 1.2e-28 ywbE S Uncharacterized conserved protein (DUF2196)
HIMGIKDF_03829 8.9e-223 ywbD 2.1.1.191 J Methyltransferase
HIMGIKDF_03830 4.4e-67 ywbC 4.4.1.5 E glyoxalase
HIMGIKDF_03831 1.8e-127 ywbB S Protein of unknown function (DUF2711)
HIMGIKDF_03832 5.8e-247 celB G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMGIKDF_03833 1.6e-277 epr 3.4.21.62 O Belongs to the peptidase S8 family
HIMGIKDF_03834 5.2e-243 scrA 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_03835 4e-153 sacY K transcriptional antiterminator
HIMGIKDF_03836 7e-169 gspA M General stress
HIMGIKDF_03837 1.7e-128 ywaF S Integral membrane protein
HIMGIKDF_03838 8.1e-88 ywaE K Transcriptional regulator
HIMGIKDF_03839 4.4e-233 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HIMGIKDF_03840 1.4e-251 ywaD 3.4.11.10, 3.4.11.6 S PA domain
HIMGIKDF_03841 5e-116 ywaC 2.7.6.5 S protein conserved in bacteria
HIMGIKDF_03842 5.4e-167 menA 2.5.1.74 H Belongs to the MenA family. Type 1 subfamily
HIMGIKDF_03843 5e-14 S D-Ala-teichoic acid biosynthesis protein
HIMGIKDF_03844 7.9e-293 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_03845 1.2e-232 dltB M membrane protein involved in D-alanine export
HIMGIKDF_03846 1.5e-36 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HIMGIKDF_03847 2.3e-231 dltD M COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HIMGIKDF_03848 6.6e-139 dltE M Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03849 3.1e-206 ilvE 2.6.1.42 E Branched-chain amino acid aminotransferase
HIMGIKDF_03850 1.1e-253 licH 3.2.1.86 GT4 G COG1486 Alpha-galactosidases 6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases
HIMGIKDF_03851 6.7e-38 licA 2.7.1.196, 2.7.1.205 G phosphotransferase system
HIMGIKDF_03852 7.4e-250 licC G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HIMGIKDF_03853 2.3e-50 licB 2.7.1.196, 2.7.1.205 G transporter subunit IIB
HIMGIKDF_03854 0.0 licR 2.7.1.202 GKT Mga helix-turn-helix domain
HIMGIKDF_03855 1.1e-19 yxzF
HIMGIKDF_03856 1e-110 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HIMGIKDF_03857 0.0 katX 1.11.1.6 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMGIKDF_03858 2.1e-216 yxlH EGP Major facilitator Superfamily
HIMGIKDF_03859 1.8e-139 yxlG S COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component
HIMGIKDF_03860 5.1e-167 yxlF V ABC transporter, ATP-binding protein
HIMGIKDF_03861 7.6e-28 yxlE S Phospholipase_D-nuclease N-terminal
HIMGIKDF_03862 1.2e-31
HIMGIKDF_03863 3.9e-48 yxlC S Family of unknown function (DUF5345)
HIMGIKDF_03864 4.7e-91 sigY K Belongs to the sigma-70 factor family. ECF subfamily
HIMGIKDF_03865 2.3e-254 yxlA F Belongs to the purine-cytosine permease (2.A.39) family
HIMGIKDF_03866 8e-162 nnrD 4.2.1.136, 5.1.99.6 G Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HIMGIKDF_03867 0.0 cydD V ATP-binding protein
HIMGIKDF_03868 0.0 cydD V ATP-binding
HIMGIKDF_03869 2.9e-190 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase, subunit II
HIMGIKDF_03870 1.3e-268 cydA 1.10.3.14 C oxidase, subunit
HIMGIKDF_03871 1.5e-229 cimH C COG3493 Na citrate symporter
HIMGIKDF_03872 3.3e-120 3.4.24.84 O Peptidase family M48
HIMGIKDF_03873 2.8e-235 3.4.24.84 O Peptidase family M48
HIMGIKDF_03875 3e-156 yxkH G Polysaccharide deacetylase
HIMGIKDF_03876 5.9e-205 msmK P Belongs to the ABC transporter superfamily
HIMGIKDF_03877 4.8e-165 lrp QT PucR C-terminal helix-turn-helix domain
HIMGIKDF_03878 2.5e-275 aldY 1.2.1.3 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMGIKDF_03879 1.9e-147 yxkD S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HIMGIKDF_03880 4.1e-73 yxkC S Domain of unknown function (DUF4352)
HIMGIKDF_03881 4.6e-196 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HIMGIKDF_03882 1.3e-95 yxkA S Phosphatidylethanolamine-binding protein
HIMGIKDF_03883 1.9e-166 yxjO K LysR substrate binding domain
HIMGIKDF_03884 2.4e-78 S Protein of unknown function (DUF1453)
HIMGIKDF_03885 1.5e-193 yxjM T Signal transduction histidine kinase
HIMGIKDF_03886 8.9e-116 K helix_turn_helix, Lux Regulon
HIMGIKDF_03887 3.6e-235 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HIMGIKDF_03890 1e-87 yxjI S LURP-one-related
HIMGIKDF_03891 5.5e-222 yxjG 2.1.1.14 E Methionine synthase
HIMGIKDF_03892 1e-220 yxjG 2.1.1.14 E Methionine synthase
HIMGIKDF_03893 1.3e-137 IQ Catalyzes the formation of acetoacetate from 3-hydroxybutyrate
HIMGIKDF_03894 5.2e-116 scoB 2.8.3.5 I COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit
HIMGIKDF_03895 1.4e-130 scoA 2.8.3.5 I COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HIMGIKDF_03896 2.6e-253 yxjC EG COG2610 H gluconate symporter and related permeases
HIMGIKDF_03897 2.2e-145 rlmA 2.1.1.187 Q Methyltransferase domain
HIMGIKDF_03898 1.9e-212 nupG F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMGIKDF_03899 1.2e-22 T Domain of unknown function (DUF4163)
HIMGIKDF_03900 2.7e-48 yxiS
HIMGIKDF_03901 0.0 katE 1.11.1.6, 3.5.1.124 P serves to protect cells from the toxic effects of hydrogen peroxide
HIMGIKDF_03902 6.6e-224 citH C Citrate transporter
HIMGIKDF_03903 5e-144 exoK GH16 M licheninase activity
HIMGIKDF_03904 8.3e-151 licT K transcriptional antiterminator
HIMGIKDF_03905 6.6e-114
HIMGIKDF_03906 3e-232 yxiO S COG2270 Permeases of the major facilitator superfamily
HIMGIKDF_03907 1e-265 dbpA 3.6.4.13 JKL DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes
HIMGIKDF_03908 7.5e-219 3.2.1.14 GH18 E GDSL-like Lipase/Acylhydrolase
HIMGIKDF_03911 1.6e-48 yxiJ S YxiJ-like protein
HIMGIKDF_03912 1.2e-96 yxiI S Protein of unknown function (DUF2716)
HIMGIKDF_03913 3.8e-81
HIMGIKDF_03914 4.9e-46
HIMGIKDF_03915 3.7e-75 yxiG
HIMGIKDF_03916 6.4e-63
HIMGIKDF_03917 1.7e-84
HIMGIKDF_03918 1.5e-71 yxxG
HIMGIKDF_03919 0.0 wapA M COG3209 Rhs family protein
HIMGIKDF_03920 2.9e-168 yxxF EG EamA-like transporter family
HIMGIKDF_03921 1.1e-72 yxiE T Belongs to the universal stress protein A family
HIMGIKDF_03922 6.6e-281 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMGIKDF_03923 0.0 bglF 2.7.1.193, 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G phosphotransferase system
HIMGIKDF_03924 3.6e-51
HIMGIKDF_03925 2.2e-78 S SMI1 / KNR4 family
HIMGIKDF_03926 0.0 S nuclease activity
HIMGIKDF_03927 3.6e-39 yxiC S Family of unknown function (DUF5344)
HIMGIKDF_03928 2.1e-21 S Domain of unknown function (DUF5082)
HIMGIKDF_03929 6.3e-284 yxiA 3.2.1.99 GH43 G Belongs to the glycosyl hydrolase 43 family
HIMGIKDF_03930 5e-78 hutP K Antiterminator that binds to cis-acting regulatory sequences on the mRNA in the presence of histidine, thereby suppressing transcription termination and activating the hut operon for histidine utilization
HIMGIKDF_03931 2.3e-284 hutH 4.3.1.3 E Histidine ammonia-lyase
HIMGIKDF_03932 0.0 hutU 4.2.1.49 E Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
HIMGIKDF_03933 1.2e-238 hutI 3.5.2.7 Q Imidazolone-5-propionate hydrolase
HIMGIKDF_03934 8e-182 hutG 3.5.3.11, 3.5.3.8 E Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide
HIMGIKDF_03935 6.1e-252 lysP E amino acid
HIMGIKDF_03936 4.2e-234 pdp 2.4.2.2, 2.4.2.4 F phosphorylase
HIMGIKDF_03937 9.8e-206 nupC F Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
HIMGIKDF_03938 7e-116 deoC 4.1.2.4 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HIMGIKDF_03939 3.5e-174 deoR K COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain
HIMGIKDF_03940 3e-153 yxxB S Domain of Unknown Function (DUF1206)
HIMGIKDF_03941 6.8e-201 eutH E Ethanolamine utilisation protein, EutH
HIMGIKDF_03942 2e-255 yxeQ S MmgE/PrpD family
HIMGIKDF_03943 3.8e-215 yxeP 3.5.1.47 E hydrolase activity
HIMGIKDF_03944 5.4e-133 yxeO 3.6.3.21 P ABC transporter, ATP-binding protein
HIMGIKDF_03945 5.4e-108 yxeN P COG0765 ABC-type amino acid transport system, permease component
HIMGIKDF_03946 2.5e-144 yxeM M Belongs to the bacterial solute-binding protein 3 family
HIMGIKDF_03947 7.3e-94 yxeL K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HIMGIKDF_03948 2.2e-254 yxeK C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HIMGIKDF_03950 8.8e-192 yxeI 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HIMGIKDF_03951 6.2e-151 yidA S hydrolases of the HAD superfamily
HIMGIKDF_03954 1.3e-20 yxeE
HIMGIKDF_03955 1.9e-16 yxeD
HIMGIKDF_03956 8.5e-69
HIMGIKDF_03957 6e-177 fhuD P ABC transporter
HIMGIKDF_03958 1.5e-58 yxeA S Protein of unknown function (DUF1093)
HIMGIKDF_03959 0.0 yxdM V ABC transporter (permease)
HIMGIKDF_03960 9.4e-141 yxdL V ABC transporter, ATP-binding protein
HIMGIKDF_03961 1.3e-182 T PhoQ Sensor
HIMGIKDF_03962 4.2e-124 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_03963 5.4e-161 iolJ 4.1.2.13, 4.1.2.29 F Produces dihydroxyacetone phosphate (DHAP or glycerone phosphate) and malonic semialdehyde (MSA or 3-oxopropanoate) from 6-phospho-5-dehydro-2-deoxy-D-gluconate (DKGP)
HIMGIKDF_03964 1.9e-139 iolI 5.3.99.11 G Involved in the reversible interconverion of 2-keto-myo- inositol (2KMI, inosose or 2,4,6 3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5 4,6- pentahydroxycyclohexanone)
HIMGIKDF_03965 2.3e-167 iolH G Xylose isomerase-like TIM barrel
HIMGIKDF_03966 2.8e-196 iolG 1.1.1.18, 1.1.1.369 S Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively
HIMGIKDF_03967 1.3e-235 iolF EGP Major facilitator Superfamily
HIMGIKDF_03968 2.1e-176 iolE 4.2.1.44 G Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)
HIMGIKDF_03969 0.0 iolD 3.7.1.22 E Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)
HIMGIKDF_03970 2.9e-179 iolC 2.7.1.92 G Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP)
HIMGIKDF_03971 1.1e-155 iolB 5.3.1.30 G Involved in the isomerization of 5-deoxy-glucuronate (5DG) to 5-dehydro-2-deoxy-D-gluconate (DKG or 2-deoxy-5-keto-D- gluconate)
HIMGIKDF_03972 1.4e-281 iolA 1.2.1.18, 1.2.1.27 C Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively
HIMGIKDF_03973 3.3e-138 iolR K COG1349 Transcriptional regulators of sugar metabolism
HIMGIKDF_03974 3.7e-176 iolS C Aldo keto reductase
HIMGIKDF_03976 8.3e-48 yxcD S Protein of unknown function (DUF2653)
HIMGIKDF_03977 2.3e-246 csbC EGP Major facilitator Superfamily
HIMGIKDF_03978 0.0 htpG O Molecular chaperone. Has ATPase activity
HIMGIKDF_03980 5.7e-152 IQ Enoyl-(Acyl carrier protein) reductase
HIMGIKDF_03981 2.2e-215 yxbF K Bacterial regulatory proteins, tetR family
HIMGIKDF_03982 1.4e-248 alkH 1.2.1.3 C Belongs to the aldehyde dehydrogenase family
HIMGIKDF_03983 1.6e-85 yxbD 3.2.2.20 K Acetyltransferase (GNAT) domain
HIMGIKDF_03984 2.2e-187 yxbC 1.14.11.47 S A domain family that is part of the cupin metalloenzyme superfamily.
HIMGIKDF_03985 3.3e-127 yxbB Q Met-10+ like-protein
HIMGIKDF_03986 4.9e-44 S Coenzyme PQQ synthesis protein D (PqqD)
HIMGIKDF_03987 1.1e-86 yxnB
HIMGIKDF_03988 0.0 asnB 6.3.5.4 E Asparagine synthase
HIMGIKDF_03989 7.6e-214 yxaM U MFS_1 like family
HIMGIKDF_03990 6.8e-93 S PQQ-like domain
HIMGIKDF_03991 3.5e-65 S Family of unknown function (DUF5391)
HIMGIKDF_03992 1.1e-75 yxaI S membrane protein domain
HIMGIKDF_03993 1.4e-228 P Protein of unknown function (DUF418)
HIMGIKDF_03994 1.5e-199 yxaG 1.13.11.24 S AraC-like ligand binding domain
HIMGIKDF_03995 7.1e-101 yxaF K Transcriptional regulator
HIMGIKDF_03996 2.3e-201 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
HIMGIKDF_03997 4.4e-71 yxaD K helix_turn_helix multiple antibiotic resistance protein
HIMGIKDF_03998 5.2e-50 S LrgA family
HIMGIKDF_03999 2.6e-118 yxaC M effector of murein hydrolase
HIMGIKDF_04000 1.3e-193 yxaB GM Polysaccharide pyruvyl transferase
HIMGIKDF_04001 7e-209 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HIMGIKDF_04002 7.3e-127 gntR K transcriptional
HIMGIKDF_04003 4.6e-304 gntK 2.7.1.12, 2.7.1.17, 2.7.1.5 G Belongs to the FGGY kinase family
HIMGIKDF_04004 4.5e-231 gntP EG COG2610 H gluconate symporter and related permeases
HIMGIKDF_04005 3.8e-273 gnd 1.1.1.343, 1.1.1.44 G Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HIMGIKDF_04006 2.1e-105 ahpC 1.11.1.15 O Alkyl hydroperoxide reductase
HIMGIKDF_04007 3.8e-287 ahpF O Alkyl hydroperoxide reductase
HIMGIKDF_04008 6.4e-292 bglA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HIMGIKDF_04009 2.5e-19 bglF G phosphotransferase system
HIMGIKDF_04010 1.3e-128 yydK K Transcriptional regulator
HIMGIKDF_04011 7.6e-13
HIMGIKDF_04012 3.3e-119 S ABC-2 family transporter protein
HIMGIKDF_04013 1.8e-110 prrC P ABC transporter
HIMGIKDF_04014 8.4e-134 yydH O Peptidase M50
HIMGIKDF_04015 7.7e-185 S Radical SAM superfamily
HIMGIKDF_04016 8e-12
HIMGIKDF_04017 0.0 fbp 3.1.3.11 G Firmicute fructose-1,6-bisphosphatase
HIMGIKDF_04018 0.0 S Uncharacterised protein conserved in bacteria (DUF2326)
HIMGIKDF_04019 3.5e-65
HIMGIKDF_04020 7.3e-280 S Calcineurin-like phosphoesterase
HIMGIKDF_04021 5.2e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HIMGIKDF_04022 1.1e-09 S YyzF-like protein
HIMGIKDF_04023 4.2e-71
HIMGIKDF_04024 3e-234 fdhA 1.1.1.1, 1.1.1.14, 1.1.1.284, 1.2.1.46 E COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases
HIMGIKDF_04026 2.1e-33 yycQ S Protein of unknown function (DUF2651)
HIMGIKDF_04027 1.6e-221 yycP
HIMGIKDF_04028 5.8e-132 yycO S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HIMGIKDF_04029 3.1e-86 yycN 2.3.1.128 K Acetyltransferase
HIMGIKDF_04030 5e-188 S aspartate phosphatase
HIMGIKDF_04032 2.3e-167 rocF 3.5.3.1, 3.5.3.11 E Belongs to the arginase family
HIMGIKDF_04033 9.7e-261 rocE E amino acid
HIMGIKDF_04034 1.7e-234 rocD 2.6.1.11, 2.6.1.13, 2.6.1.17 E Catalyzes the interconversion of ornithine to glutamate semialdehyde
HIMGIKDF_04035 1.5e-258 rocR KT COG3829 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains
HIMGIKDF_04036 8.4e-221 htrA 3.4.21.107 O COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HIMGIKDF_04037 8.7e-150 vicX 3.1.26.11 S COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I
HIMGIKDF_04038 7.3e-155 yycI S protein conserved in bacteria
HIMGIKDF_04039 3.6e-260 yycH S protein conserved in bacteria
HIMGIKDF_04040 0.0 vicK 2.7.13.3 T Histidine kinase
HIMGIKDF_04041 1.1e-132 T COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
HIMGIKDF_04046 1.7e-248 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HIMGIKDF_04047 8e-78 yycE 3.4.21.26, 5.3.1.24 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_04048 3e-251 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HIMGIKDF_04049 1.9e-29 yycD S Uncharacterized protein conserved in bacteria (DUF2188)
HIMGIKDF_04051 1.9e-15 yycC K YycC-like protein
HIMGIKDF_04052 8.4e-221 yeaN P COG2807 Cyanate permease
HIMGIKDF_04053 0.0 yycA M COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HIMGIKDF_04054 2.2e-73 rplI J binds to the 23S rRNA
HIMGIKDF_04055 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HIMGIKDF_04056 2.9e-160 yybS S membrane
HIMGIKDF_04058 3.9e-84 cotF M Spore coat protein
HIMGIKDF_04059 1.4e-68 ydeP3 K Transcriptional regulator
HIMGIKDF_04060 1.1e-164 ppaC 3.6.1.1 C Inorganic pyrophosphatase
HIMGIKDF_04061 1.3e-70
HIMGIKDF_04063 2.3e-240 yybO G COG0477 Permeases of the major facilitator superfamily
HIMGIKDF_04064 1e-16
HIMGIKDF_04065 1.3e-78 yybN S Protein of unknown function (DUF2712)
HIMGIKDF_04066 4.1e-125
HIMGIKDF_04067 9e-122
HIMGIKDF_04068 2e-127 S Protein of unknown function (DUF2705)
HIMGIKDF_04069 2.6e-115 V ATPases associated with a variety of cellular activities
HIMGIKDF_04070 6.2e-132
HIMGIKDF_04071 5.9e-67 yybH S SnoaL-like domain
HIMGIKDF_04072 3e-124 yybG S Pentapeptide repeat-containing protein
HIMGIKDF_04073 3.2e-220 ynfM EGP Major facilitator Superfamily
HIMGIKDF_04074 2.1e-165 yybE K Transcriptional regulator
HIMGIKDF_04075 2e-79 yjcF S Acetyltransferase (GNAT) domain
HIMGIKDF_04076 2.7e-77 yybC
HIMGIKDF_04077 3e-127 S Metallo-beta-lactamase superfamily
HIMGIKDF_04078 5.6e-77 yybA 2.3.1.57 K transcriptional
HIMGIKDF_04079 5.9e-79 yjcF S Acetyltransferase (GNAT) domain
HIMGIKDF_04080 1.5e-101 yyaS S Membrane
HIMGIKDF_04081 5.4e-100 yyaR K Acetyltransferase (GNAT) domain
HIMGIKDF_04082 5.4e-67 yyaQ S YjbR
HIMGIKDF_04083 1.7e-107 yyaP 1.5.1.3 H RibD C-terminal domain
HIMGIKDF_04084 1.7e-249 tetL EGP Major facilitator Superfamily
HIMGIKDF_04085 9.7e-44 yyaL O Highly conserved protein containing a thioredoxin domain
HIMGIKDF_04086 5.1e-61 yyaN K MerR HTH family regulatory protein
HIMGIKDF_04087 3.3e-161 yyaM EG EamA-like transporter family
HIMGIKDF_04088 0.0 yyaL O COG1331 Highly conserved protein containing a thioredoxin domain
HIMGIKDF_04089 9.5e-169 yyaK S CAAX protease self-immunity
HIMGIKDF_04090 3.8e-246 EGP Major facilitator superfamily
HIMGIKDF_04091 5.1e-96 maa 2.3.1.79 S Bacterial transferase hexapeptide (six repeats)
HIMGIKDF_04092 4e-68 yyaH 4.4.1.5 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HIMGIKDF_04093 3.3e-180 ccpB 3.5.1.4, 5.1.1.1 K Transcriptional regulator
HIMGIKDF_04094 8.1e-145 xth 3.1.11.2 L exodeoxyribonuclease III
HIMGIKDF_04095 5.1e-37 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HIMGIKDF_04096 2.9e-69 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HIMGIKDF_04097 4.3e-46 rpsF J Binds together with S18 to 16S ribosomal RNA
HIMGIKDF_04098 4e-201 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HIMGIKDF_04099 0.0 yyaE C Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HIMGIKDF_04100 2.3e-33 yyzM S protein conserved in bacteria
HIMGIKDF_04101 8.1e-177 yyaD S Membrane
HIMGIKDF_04102 1.6e-111 yyaC S Sporulation protein YyaC
HIMGIKDF_04103 2.1e-149 spo0J K Belongs to the ParB family
HIMGIKDF_04104 2.2e-134 soj D COG1192 ATPases involved in chromosome partitioning
HIMGIKDF_04105 1.5e-74 S Bacterial PH domain
HIMGIKDF_04106 1.9e-150 noc D Effects nucleoid occlusion by binding relatively nonspecifically to DNA and preventing the assembly of the division machinery in the vicinity of the nucleoid, especially under conditions that disturb the cell cycle. It helps to coordinate cell division and chromosome segregation by preventing the formation of the Z ring through the nucleoid, which would cause chromosome breakage
HIMGIKDF_04107 2.2e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of guanine in position 535 of 16S rRNA
HIMGIKDF_04108 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HIMGIKDF_04109 3.1e-251 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HIMGIKDF_04110 6.5e-108 jag S single-stranded nucleic acid binding R3H
HIMGIKDF_04111 1.7e-118 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HIMGIKDF_04112 3e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)