ORF_ID e_value Gene_name EC_number CAZy COGs Description
PANGELCK_00002 9.1e-78 hmpT S cog cog4720
PANGELCK_00003 1.7e-134 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H phosphomethylpyrimidine kinase
PANGELCK_00004 1.9e-138 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
PANGELCK_00005 4.2e-193 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
PANGELCK_00006 6e-303 dnaK O Heat shock 70 kDa protein
PANGELCK_00007 8.2e-64 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PANGELCK_00008 3.7e-185 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
PANGELCK_00009 8.8e-99 acmA 3.2.1.17, 3.4.17.14, 3.5.1.28 NU Muramidase (Flagellum-specific)
PANGELCK_00010 1.1e-139 vanY 3.4.17.14 M D-alanyl-D-alanine carboxypeptidase
PANGELCK_00011 4.3e-132 ais G Phosphoglycerate mutase
PANGELCK_00012 1.6e-241 XK27_08635 S UPF0210 protein
PANGELCK_00013 2.3e-38 gcvR T UPF0237 protein
PANGELCK_00014 2.2e-232 capA M Bacterial capsule synthesis protein
PANGELCK_00015 8.6e-148 srtB 3.4.22.70 S Sortase family
PANGELCK_00017 4.5e-29 K Helix-turn-helix domain
PANGELCK_00018 6e-46 L PFAM Integrase catalytic region
PANGELCK_00019 3.7e-163 2.1.1.37 H C-5 cytosine-specific DNA methylase
PANGELCK_00020 1e-34 S NgoFVII restriction endonuclease
PANGELCK_00021 1.4e-82
PANGELCK_00022 3.5e-81
PANGELCK_00023 1.2e-184
PANGELCK_00024 3.8e-311 L Z1 domain
PANGELCK_00025 9.9e-15 S Protein of unknown function (DUF1211)
PANGELCK_00027 3.4e-51 frnE Q DSBA-like thioredoxin domain
PANGELCK_00029 5.9e-158 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PANGELCK_00030 5.5e-47 trxA O Belongs to the thioredoxin family
PANGELCK_00031 2.9e-98 M1-798 K Rhodanese Homology Domain
PANGELCK_00032 4.1e-42 int2 L Belongs to the 'phage' integrase family
PANGELCK_00033 1.2e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
PANGELCK_00034 2e-79 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PANGELCK_00035 5.1e-22 K Transcriptional
PANGELCK_00037 5.4e-153 degV S DegV family
PANGELCK_00038 6e-91 yacP S RNA-binding protein containing a PIN domain
PANGELCK_00039 9.7e-135 trmH 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PANGELCK_00041 2.7e-67 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
PANGELCK_00042 1.5e-255 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
PANGELCK_00044 2.5e-112 cysE 2.3.1.30 E serine acetyltransferase
PANGELCK_00045 3.9e-139 S SseB protein N-terminal domain
PANGELCK_00046 0.0 pnp 2.7.7.8 J Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
PANGELCK_00047 9e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PANGELCK_00048 1.8e-229 dacA 3.4.16.4 M Belongs to the peptidase S11 family
PANGELCK_00049 0.0 clpC O Belongs to the ClpA ClpB family
PANGELCK_00050 2e-74 ctsR K Belongs to the CtsR family
PANGELCK_00051 1.6e-82 S Putative small multi-drug export protein
PANGELCK_00052 1e-182 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PANGELCK_00053 7.4e-138 rpsB J Belongs to the universal ribosomal protein uS2 family
PANGELCK_00054 4.2e-106 ahpC 1.11.1.15 O alkyl hydroperoxide reductase
PANGELCK_00055 8.6e-287 ahpF O alkyl hydroperoxide reductase
PANGELCK_00057 3.3e-92 S reductase
PANGELCK_00058 3.3e-71 badR K Transcriptional regulator, marr family
PANGELCK_00059 1.2e-35 XK27_02060 S Transglycosylase associated protein
PANGELCK_00060 3e-237 pepS E COG2309 Leucyl aminopeptidase (aminopeptidase T)
PANGELCK_00061 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PANGELCK_00066 1.9e-07
PANGELCK_00079 3.1e-162 ppaC 3.6.1.1 C inorganic pyrophosphatase
PANGELCK_00080 9.2e-99 S Domain of unknown function (DUF1803)
PANGELCK_00081 7.8e-102 ygaC J Belongs to the UPF0374 family
PANGELCK_00082 1.6e-135 recX 2.4.1.337 GT4 S Regulatory protein RecX
PANGELCK_00083 2.6e-247 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PANGELCK_00084 5.2e-192 asnA 6.3.1.1 E aspartate--ammonia ligase
PANGELCK_00085 8.2e-257 lysC 2.7.2.4 E Belongs to the aspartokinase family
PANGELCK_00086 1.6e-117 S HAD hydrolase, family IA, variant 3
PANGELCK_00087 4.8e-140 phaB 5.3.3.14, 5.3.3.18 I Belongs to the enoyl-CoA hydratase isomerase family
PANGELCK_00088 5.2e-72 marR K Transcriptional regulator, MarR family
PANGELCK_00089 1.3e-171 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PANGELCK_00090 3.3e-30 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PANGELCK_00091 1.3e-171 fabK 1.3.1.9 S 2-Nitropropane dioxygenase
PANGELCK_00092 4.7e-163 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
PANGELCK_00093 1.1e-125 IQ reductase
PANGELCK_00094 2.6e-233 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
PANGELCK_00095 3.3e-54 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
PANGELCK_00096 1.5e-71 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
PANGELCK_00097 8.3e-257 accC 6.3.4.14, 6.4.1.2 I An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
PANGELCK_00098 2.7e-160 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PANGELCK_00099 5.1e-139 accA 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
PANGELCK_00100 4.7e-90 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
PANGELCK_00101 2.4e-207 rny D Endoribonuclease that initiates mRNA decay
PANGELCK_00102 9.2e-109 fruR K transcriptional
PANGELCK_00103 7.6e-166 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PANGELCK_00104 0.0 fruA 2.7.1.202 G phosphotransferase system
PANGELCK_00105 4.5e-255 gor 1.8.1.7 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PANGELCK_00106 3.3e-228 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PANGELCK_00108 5.2e-212 iscS2 2.8.1.7 E Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes
PANGELCK_00109 3.1e-223 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PANGELCK_00110 5.3e-289 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PANGELCK_00111 1.8e-253 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PANGELCK_00112 8.1e-83 2.3.1.128 K acetyltransferase
PANGELCK_00113 4.5e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
PANGELCK_00114 1.5e-46 rpmA J Belongs to the bacterial ribosomal protein bL27 family
PANGELCK_00115 1.6e-131 ydaF_2 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
PANGELCK_00116 5e-63 WQ51_03320 S cog cog4835
PANGELCK_00117 2.8e-146 XK27_08360 S EDD domain protein, DegV family
PANGELCK_00118 1.5e-138 dapB 1.17.1.8 E Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate
PANGELCK_00119 2.5e-217 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
PANGELCK_00120 0.0 yfmR S abc transporter atp-binding protein
PANGELCK_00121 1.7e-26 U response to pH
PANGELCK_00122 3.7e-129 3.6.1.13, 3.6.1.55 F AdP-ribose pyrophosphatase
PANGELCK_00123 8e-210 nadD 2.7.1.22, 2.7.7.1, 2.7.7.18, 3.6.1.55 H adenylyltransferase
PANGELCK_00124 1.4e-256 gdhA 1.4.1.4 E Belongs to the Glu Leu Phe Val dehydrogenases family
PANGELCK_00125 3.1e-266 S Psort location CytoplasmicMembrane, score
PANGELCK_00126 3.9e-69 def_1 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
PANGELCK_00130 1.3e-20 S YfhD-like protein
PANGELCK_00132 3.6e-17 U Saccharomyces cerevisiae
PANGELCK_00133 0.0 M domain protein
PANGELCK_00134 0.0 zmpB M signal peptide protein, YSIRK family
PANGELCK_00135 0.0 GM domain, Protein
PANGELCK_00136 4.6e-219 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
PANGELCK_00137 0.0 sbcC L ATPase involved in DNA repair
PANGELCK_00138 0.0 M family 8
PANGELCK_00139 1.9e-212 secY2 U Part of the accessory SecA2 SecY2 system specifically required for export of
PANGELCK_00140 2.4e-292 asp1 S Accessory Sec system protein Asp1
PANGELCK_00141 1.5e-286 asp2 3.4.11.5 S Accessory Sec system protein Asp2
PANGELCK_00142 6.5e-78 asp3 S Accessory Sec system protein Asp3
PANGELCK_00143 0.0 secA2 U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PANGELCK_00144 1.7e-279 gtf1 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PANGELCK_00145 5.7e-242 gtf2 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PANGELCK_00146 2.6e-17 S Accessory secretory protein Sec Asp4
PANGELCK_00147 3.6e-16 S Accessory secretory protein Sec, Asp5
PANGELCK_00148 1.1e-181 nss M transferase activity, transferring glycosyl groups
PANGELCK_00149 0.0 sraP UW Hep Hag repeat protein
PANGELCK_00154 1.8e-102 tcyB_2 P ABC transporter (permease)
PANGELCK_00155 3.2e-153 endA F DNA RNA non-specific endonuclease
PANGELCK_00156 7.2e-26 epuA S DNA-directed RNA polymerase subunit beta
PANGELCK_00157 5.5e-231 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PANGELCK_00158 4.8e-11 S Protein of unknown function (DUF1146)
PANGELCK_00159 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PANGELCK_00160 3.2e-134 G Domain of unknown function (DUF4832)
PANGELCK_00161 2.7e-83 S membrane
PANGELCK_00162 3e-96 P VTC domain
PANGELCK_00163 5.9e-223 cotH M CotH kinase protein
PANGELCK_00164 6.4e-183 pelG M Putative exopolysaccharide Exporter (EPS-E)
PANGELCK_00165 9.4e-272 pelF GT4 M Domain of unknown function (DUF3492)
PANGELCK_00166 0.0 S Uncharacterised protein conserved in bacteria (DUF2194)
PANGELCK_00167 8.5e-149
PANGELCK_00168 1.5e-274 5.1.3.2 GM Psort location CytoplasmicMembrane, score
PANGELCK_00169 4.6e-211 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PANGELCK_00170 1.9e-172 birA 6.3.4.15 HK Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
PANGELCK_00171 1e-301 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PANGELCK_00172 3.1e-84 ytsP 1.8.4.14 T GAF domain-containing protein
PANGELCK_00173 2.2e-160 miaA 2.5.1.75 J Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PANGELCK_00174 3.2e-20 WQ51_02665 S Protein of unknown function (DUF3042)
PANGELCK_00177 1.1e-56 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
PANGELCK_00178 3.8e-213 XK27_05110 P Chloride transporter ClC family
PANGELCK_00179 1.9e-40 pheA 1.3.1.12, 2.3.1.79, 4.2.1.51, 5.4.99.5 E Chorismate mutase
PANGELCK_00180 8.6e-279 clcA P Chloride transporter, ClC family
PANGELCK_00181 1e-75 fld C Flavodoxin
PANGELCK_00182 4.8e-18 XK27_08880
PANGELCK_00183 4.7e-126 XK27_08875 O Zinc-dependent metalloprotease
PANGELCK_00184 1.1e-147 estA CE1 S Esterase
PANGELCK_00185 1.6e-310 rnjB S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PANGELCK_00186 3.1e-136 XK27_08845 S abc transporter atp-binding protein
PANGELCK_00187 2.6e-147 XK27_08840 S Belongs to the binding-protein-dependent transport system permease family
PANGELCK_00188 2.4e-176 XK27_08835 S ABC transporter substrate binding protein
PANGELCK_00189 1.7e-18 S Domain of unknown function (DUF4649)
PANGELCK_00190 0.0 Q the current gene model (or a revised gene model) may contain a frame shift
PANGELCK_00195 4.9e-111 mreC M Involved in formation and maintenance of cell shape
PANGELCK_00196 1.8e-82 mreD M rod shape-determining protein MreD
PANGELCK_00197 1.3e-85 usp 3.5.1.28 CBM50 S CHAP domain
PANGELCK_00198 9.5e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PANGELCK_00199 9.4e-217 araT 2.6.1.1 E Aminotransferase
PANGELCK_00200 1.4e-139 recO L Involved in DNA repair and RecF pathway recombination
PANGELCK_00201 9.2e-184 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
PANGELCK_00202 8.1e-30 acpP1 IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
PANGELCK_00203 8.9e-130 purC 4.1.1.21, 4.3.2.2, 6.3.2.6 F Belongs to the SAICAR synthetase family
PANGELCK_00204 0.0 purL 6.3.5.3 F Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PANGELCK_00205 5.1e-273 purF 2.4.2.14 F Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
PANGELCK_00206 2.5e-189 purM 6.3.3.1, 6.3.4.13 F Phosphoribosylformylglycinamidine cyclo-ligase
PANGELCK_00207 3.7e-99 purN 2.1.2.2 F Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
PANGELCK_00208 2.4e-292 purH 2.1.2.3, 3.5.4.10 F Bifunctional purine biosynthesis protein PurH
PANGELCK_00209 2.3e-156 S CHAP domain
PANGELCK_00210 2.1e-238 purD 6.3.4.13 F Belongs to the GARS family
PANGELCK_00211 1.6e-80 purE 5.4.99.18 F Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PANGELCK_00212 1.8e-201 purK 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PANGELCK_00214 9.6e-247 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
PANGELCK_00215 2.1e-12
PANGELCK_00218 0.0 argS 6.1.1.19 J Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PANGELCK_00219 3.4e-68 argR K Regulates arginine biosynthesis genes
PANGELCK_00220 1.8e-54 ymcA 3.6.3.21 S Belongs to the UPF0342 family
PANGELCK_00221 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PANGELCK_00222 3e-78 S Protein of unknown function (DUF3021)
PANGELCK_00223 1.4e-69 K LytTr DNA-binding domain
PANGELCK_00225 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PANGELCK_00227 7.8e-103 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
PANGELCK_00228 5.6e-106 tag 3.2.2.20 L 3-methyladenine DNA glycosylase
PANGELCK_00229 1.3e-224 cinA 3.5.1.42 S Belongs to the CinA family
PANGELCK_00230 6.8e-204 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PANGELCK_00231 3.9e-66 spxA_2 1.20.4.1 P Belongs to the ArsC family
PANGELCK_00232 1.3e-09 sbcC L Putative exonuclease SbcCD, C subunit
PANGELCK_00233 1.1e-147 peb1A ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PANGELCK_00234 2.7e-140 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_00235 3.8e-128 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PANGELCK_00236 3.6e-228 vicK 2.7.13.3 T Histidine kinase
PANGELCK_00237 1.7e-153 vicX 3.1.26.11 S Metal-dependent hydrolases of the beta-lactamase superfamily I
PANGELCK_00238 1.5e-56 S Protein of unknown function (DUF454)
PANGELCK_00239 1.6e-224 murM 2.3.2.10, 2.3.2.16 V protein involved in methicillin resistance
PANGELCK_00240 7.8e-146 yidA S hydrolases of the HAD superfamily
PANGELCK_00241 2.4e-96 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PANGELCK_00242 3e-39 XK27_00115 2.3.1.128 K Acetyltransferase GNAT family
PANGELCK_00243 5.3e-68 ywiB S Domain of unknown function (DUF1934)
PANGELCK_00244 0.0 pacL 3.6.3.8 P cation transport ATPase
PANGELCK_00245 1.8e-133 nfrA 1.5.1.38, 1.5.1.39 C nitroreductase
PANGELCK_00246 5.4e-158 yjjH S Calcineurin-like phosphoesterase
PANGELCK_00247 1.4e-206 queG 1.17.99.6 C Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PANGELCK_00248 5.7e-183 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PANGELCK_00249 3.2e-124 ftsE D cell division ATP-binding protein FtsE
PANGELCK_00250 7.3e-164 ftsX D Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation
PANGELCK_00251 4.3e-91 mutX 3.6.1.55 F NTP pyrophosphohydrolases including oxidative damage repair enzymes
PANGELCK_00252 9.5e-177 yubA S permease
PANGELCK_00253 8.3e-224 G COG0457 FOG TPR repeat
PANGELCK_00254 3e-96 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PANGELCK_00255 0.0 lytC 3.4.17.14, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
PANGELCK_00256 9.1e-231 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
PANGELCK_00257 3.9e-87 ebsA S Family of unknown function (DUF5322)
PANGELCK_00258 2.5e-17 M LysM domain
PANGELCK_00259 4.3e-121 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
PANGELCK_00260 1e-85 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PANGELCK_00261 8.1e-28 rpmI J Belongs to the bacterial ribosomal protein bL35 family
PANGELCK_00262 1.5e-56 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PANGELCK_00263 5.5e-75 XK27_03610 K Gnat family
PANGELCK_00264 1.8e-87 yybC
PANGELCK_00265 4.9e-27 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
PANGELCK_00266 2.6e-266 pepV 3.5.1.18 E Dipeptidase
PANGELCK_00267 2e-106 ung2 3.2.2.27 L Uracil-DNA glycosylase
PANGELCK_00268 1.3e-227 V Glucan-binding protein C
PANGELCK_00269 3.8e-20 L Transposase
PANGELCK_00270 5.7e-74 K DNA-binding transcription factor activity
PANGELCK_00271 7.2e-309 lmrA1 V abc transporter atp-binding protein
PANGELCK_00272 0.0 lmrA2 V abc transporter atp-binding protein
PANGELCK_00273 3.8e-108 K Acetyltransferase (GNAT) family
PANGELCK_00275 7.4e-112 2.7.6.5 S Region found in RelA / SpoT proteins
PANGELCK_00276 1.6e-115 T response regulator
PANGELCK_00277 5.6e-204 sptS 2.7.13.3 T Histidine kinase
PANGELCK_00278 1.7e-131 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
PANGELCK_00279 6.4e-91 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
PANGELCK_00280 1.1e-158 cvfB S Protein conserved in bacteria
PANGELCK_00281 8.2e-34 yozE S Belongs to the UPF0346 family
PANGELCK_00282 1.8e-125 sip M LysM domain protein
PANGELCK_00283 2.2e-188 phoH T phosphate starvation-inducible protein PhoH
PANGELCK_00289 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PANGELCK_00290 7.6e-160 S reductase
PANGELCK_00291 4e-107 K transcriptional regulator (lysR family)
PANGELCK_00292 4.8e-144 L Belongs to the 'phage' integrase family
PANGELCK_00293 1.8e-37 S Protein of unknown function (DUF4060)
PANGELCK_00294 6.2e-52 dam 2.1.1.37, 2.1.1.72 H Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family
PANGELCK_00295 5.1e-78 dam 2.1.1.37, 2.1.1.72 F Methylates DNA within the sequence GATC and protects the DNA from cleavage by the restriction endonuclease MboI. Although it shares sequence specificity with a number of type II restriction endonucleases and methylases, it is thought to act in postreplication mismatch repair rather than as a part of a restriction modification system. May also play a role in DNA replication
PANGELCK_00296 4.2e-74
PANGELCK_00297 6e-131 S YqaJ-like viral recombinase domain
PANGELCK_00298 3.6e-171 S DNA metabolic process
PANGELCK_00299 5.8e-48
PANGELCK_00300 8e-97
PANGELCK_00303 7.7e-21
PANGELCK_00304 3e-103
PANGELCK_00305 7.8e-134 S sequence-specific DNA binding
PANGELCK_00306 4.6e-24 S Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT
PANGELCK_00307 3.6e-86 S Putative bacterial toxin ydaT
PANGELCK_00308 1.3e-146 S DNA replication
PANGELCK_00309 3.9e-130 S DNA replication initiation
PANGELCK_00310 2.5e-135
PANGELCK_00311 1.9e-56 ybcN S bubble DNA binding
PANGELCK_00312 3.9e-23 S NINE Protein
PANGELCK_00313 1e-130 S bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity
PANGELCK_00314 5.7e-51 J Cold shock protein domain
PANGELCK_00316 1e-153 S unfolded protein binding
PANGELCK_00317 1.2e-32 essD S Bacteriophage P21 holin S
PANGELCK_00318 5.7e-91 S Phage lysozyme
PANGELCK_00319 9.7e-77 S Bacteriophage Rz lysis protein
PANGELCK_00320 1.3e-93 S DNA binding
PANGELCK_00321 1.7e-23
PANGELCK_00322 2.6e-10
PANGELCK_00325 3.1e-27 G S-layer homology domain
PANGELCK_00326 2e-108 S CAAX amino terminal protease family protein
PANGELCK_00327 1.3e-244 S Glucan-binding protein C
PANGELCK_00328 2.1e-174 coiA 3.6.4.12 S Competence protein
PANGELCK_00329 0.0 pepF E oligoendopeptidase F
PANGELCK_00330 4.5e-214 oxlT P COG0477 Permeases of the major facilitator superfamily
PANGELCK_00331 1.4e-119 yrrM 2.1.1.104 S O-Methyltransferase
PANGELCK_00332 6.2e-165 prsA 3.1.3.16, 5.2.1.8 O peptidyl-prolyl cis-trans isomerase activity
PANGELCK_00333 7.1e-86 yxjI S LURP-one-related
PANGELCK_00334 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PANGELCK_00335 3.4e-254 cshA 3.6.4.13 JKL DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
PANGELCK_00336 7.6e-150 corA P CorA-like protein
PANGELCK_00337 9.6e-62 yjqA S Bacterial PH domain
PANGELCK_00338 3.1e-96 thiT S Thiamine transporter
PANGELCK_00341 4.9e-90 Z012_04635 K sequence-specific DNA binding
PANGELCK_00342 1.5e-105 V ATPases associated with a variety of cellular activities
PANGELCK_00343 1.4e-63
PANGELCK_00344 2.5e-150 Z012_04635 K Transcriptional activator, Rgg GadR MutR family
PANGELCK_00345 4e-191 yjbB G Permeases of the major facilitator superfamily
PANGELCK_00346 5.2e-300 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PANGELCK_00348 1.9e-24
PANGELCK_00349 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00350 0.0 3.5.1.28 M domain protein
PANGELCK_00351 4.7e-137 S N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity
PANGELCK_00352 3e-89 maa 2.3.1.79 GK Maltose O-acetyltransferase
PANGELCK_00353 3.4e-65 rmaI K Transcriptional regulator, MarR family
PANGELCK_00354 7.6e-234 EGP Major facilitator Superfamily
PANGELCK_00355 2.4e-112 XK27_00785 S CAAX protease self-immunity
PANGELCK_00356 2.2e-117 mleR K Transcriptional regulator
PANGELCK_00357 1.8e-46 K Helix-turn-helix
PANGELCK_00358 4.5e-311 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme, NAD binding domain
PANGELCK_00359 1.9e-159 mleP S Sodium Bile acid symporter family
PANGELCK_00360 1.2e-100 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PANGELCK_00362 0.0 M Putative cell wall binding repeat
PANGELCK_00363 0.0 S dextransucrase activity
PANGELCK_00364 0.0 M Putative cell wall binding repeat
PANGELCK_00365 1.8e-156 pdxS 4.3.3.6 H Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
PANGELCK_00366 3.4e-98 pdxT 4.3.3.6 H Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
PANGELCK_00367 0.0 S dextransucrase activity
PANGELCK_00368 9.4e-89 S dextransucrase activity
PANGELCK_00369 0.0 S dextransucrase activity
PANGELCK_00370 0.0 S dextransucrase activity
PANGELCK_00371 0.0 S dextransucrase activity
PANGELCK_00372 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00373 2.3e-77 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00374 2.8e-253 S dextransucrase activity
PANGELCK_00376 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00377 2.6e-07 S Enterocin A Immunity
PANGELCK_00378 0.0 pepO 3.4.24.71 O Peptidase family M13
PANGELCK_00379 3.5e-33 S Immunity protein 41
PANGELCK_00380 7.5e-136 T Ser Thr phosphatase family protein
PANGELCK_00381 0.0 M Putative cell wall binding repeat
PANGELCK_00382 1.3e-224 thrE K Psort location CytoplasmicMembrane, score
PANGELCK_00383 5e-179 dhaK 2.7.1.121, 2.7.1.28, 2.7.1.29, 4.6.1.15 G Dihydroxyacetone kinase
PANGELCK_00384 5.3e-96 dhaL 2.7.1.121 S Dihydroxyacetone kinase
PANGELCK_00385 2.4e-57 dhaM 2.7.1.121 S dihydroxyacetone kinase, phosphotransfer subunit
PANGELCK_00386 6.9e-181 XK27_10475 S oxidoreductase
PANGELCK_00387 1.1e-212 BP1961 P oxidoreductase
PANGELCK_00389 1.1e-283 XK27_07020 S Belongs to the UPF0371 family
PANGELCK_00390 9.7e-212 vex1 V Efflux ABC transporter, permease protein
PANGELCK_00391 2.5e-107 vex2 V abc transporter atp-binding protein
PANGELCK_00392 7.1e-240 vex3 V Efflux ABC transporter, permease protein
PANGELCK_00393 1.5e-115 K Response regulator receiver domain protein
PANGELCK_00394 2.1e-217 vncS 2.7.13.3 T Histidine kinase
PANGELCK_00395 3.1e-303 dexB 3.2.1.10, 3.2.1.70 GH13 G COG0366 Glycosidases
PANGELCK_00396 1.7e-182 galR K Transcriptional regulator
PANGELCK_00397 2.1e-221 galK 2.7.1.6 G Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PANGELCK_00398 9.8e-288 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PANGELCK_00399 1.1e-194 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
PANGELCK_00400 7.6e-202 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
PANGELCK_00401 0.0 lacS G transporter
PANGELCK_00402 0.0 lacL 3.2.1.23 G -beta-galactosidase
PANGELCK_00403 2.6e-211 S Tetratricopeptide repeat
PANGELCK_00404 3.7e-159 yvgN C reductase
PANGELCK_00405 2.5e-30 XK27_10490
PANGELCK_00406 4.5e-39 DJ nuclease activity
PANGELCK_00407 1e-106 yoaK S Protein of unknown function (DUF1275)
PANGELCK_00408 3.9e-108 drgA C nitroreductase
PANGELCK_00409 1.2e-123 T Xre family transcriptional regulator
PANGELCK_00410 1.1e-129 T PhoQ Sensor
PANGELCK_00411 1.1e-45 S Domain of unknown function (DUF4352)
PANGELCK_00412 4.4e-127 S ABC-2 family transporter protein
PANGELCK_00413 4.1e-167 bcrA V abc transporter atp-binding protein
PANGELCK_00414 2.5e-223 pts13C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
PANGELCK_00415 2.4e-153 E Alpha/beta hydrolase of unknown function (DUF915)
PANGELCK_00416 2.6e-74 ywnA K Transcriptional regulator
PANGELCK_00417 5.3e-153 1.13.11.2 S glyoxalase
PANGELCK_00418 5.1e-110 XK27_02070 S nitroreductase
PANGELCK_00419 4.7e-171 ydhF S Aldo keto reductase
PANGELCK_00420 1.8e-96 K WHG domain
PANGELCK_00421 3.3e-121 V abc transporter atp-binding protein
PANGELCK_00422 5.6e-206 P FtsX-like permease family
PANGELCK_00423 1.7e-15 XK27_10130
PANGELCK_00425 2e-42 S Sugar efflux transporter for intercellular exchange
PANGELCK_00426 1.7e-84 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
PANGELCK_00427 7.8e-172 4.1.1.37 H Uroporphyrinogen decarboxylase (URO-D)
PANGELCK_00428 1.8e-164 ET ABC transporter substrate-binding protein
PANGELCK_00429 2.2e-109 ytmL P ABC transporter (Permease
PANGELCK_00430 2.1e-112 yxeN P ABC transporter, permease protein
PANGELCK_00431 1.3e-137 tcyC2 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_00432 0.0 S dextransucrase activity
PANGELCK_00433 4.3e-213 yfnA E amino acid
PANGELCK_00434 1.2e-50 XK27_01300 P Protein conserved in bacteria
PANGELCK_00435 2.4e-74 S Carbohydrate-binding domain-containing protein Cthe_2159
PANGELCK_00436 5.9e-15 csbD K CsbD-like
PANGELCK_00437 6.6e-100 S Protein of unknown function (DUF421)
PANGELCK_00438 2e-58 S Protein of unknown function (DUF3290)
PANGELCK_00439 1.7e-181 manA 5.3.1.8 G mannose-6-phosphate isomerase
PANGELCK_00440 4.9e-230 brnQ E Component of the transport system for branched-chain amino acids
PANGELCK_00441 1.2e-174 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PANGELCK_00443 1.5e-242 norM V Multidrug efflux pump
PANGELCK_00444 3.7e-143 K sequence-specific DNA binding
PANGELCK_00445 1.3e-277 V (ABC) transporter
PANGELCK_00446 5.2e-221 pbuX F xanthine permease
PANGELCK_00447 6.7e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
PANGELCK_00448 5.4e-124 KT Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PANGELCK_00449 8.2e-158 T Histidine kinase
PANGELCK_00450 2.3e-131 macB2 V ABC transporter, ATP-binding protein
PANGELCK_00451 0.0 V ABC transporter (permease)
PANGELCK_00452 6.1e-93 XK27_05000 S metal cluster binding
PANGELCK_00453 2.6e-30 liaI KT membrane
PANGELCK_00454 4.1e-15 liaI KT membrane
PANGELCK_00455 2e-155 XK27_09825 V abc transporter atp-binding protein
PANGELCK_00456 2.2e-131 yvfS V Transporter
PANGELCK_00457 9.5e-37
PANGELCK_00459 5.7e-79 cdd 2.4.2.4, 3.5.4.5 F cytidine deaminase activity
PANGELCK_00460 6.7e-165 yocS S Transporter
PANGELCK_00463 8.2e-157 XK27_09825 V abc transporter atp-binding protein
PANGELCK_00464 1.5e-132 yvfS V ABC-2 type transporter
PANGELCK_00465 1e-177 desK 2.7.13.3 T Histidine kinase
PANGELCK_00466 3.3e-101 desR K COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PANGELCK_00467 7.2e-186 S abc transporter atp-binding protein
PANGELCK_00468 2.4e-142 S ABC-2 family transporter protein
PANGELCK_00469 6.6e-142 S ABC-2 family transporter protein
PANGELCK_00470 1.5e-77 K Acetyltransferase (GNAT) domain
PANGELCK_00471 3.1e-84
PANGELCK_00472 4.2e-148 K sequence-specific DNA binding
PANGELCK_00473 7.8e-97 S ABC-2 family transporter protein
PANGELCK_00474 1.1e-150 V ABC transporter, ATP-binding protein
PANGELCK_00475 5.9e-142 K sequence-specific DNA binding
PANGELCK_00476 7.5e-161 yjlA EG membrane
PANGELCK_00477 0.0 fruA 3.2.1.1, 3.2.1.26, 3.2.1.65, 3.2.1.80 GH13,GH32 G Belongs to the glycosyl hydrolase 32 family
PANGELCK_00478 8e-224 2.7.1.194, 2.7.1.202, 2.7.1.204 H Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2
PANGELCK_00479 3.7e-42 ulaB 2.7.1.194 G COG3414 Phosphotransferase system galactitol-specific IIB component
PANGELCK_00480 1.4e-219 ulaA 2.7.1.194 S PTS system sugar-specific permease component
PANGELCK_00481 4e-124 tktN 2.2.1.1 G Transketolase
PANGELCK_00482 5.6e-124 tktC 2.2.1.1 G Transketolase, pyrimidine binding domain
PANGELCK_00483 2e-147 sdaAA 4.3.1.17 E L-serine dehydratase
PANGELCK_00484 3.6e-120 sdaAB 4.3.1.17 E L-serine dehydratase
PANGELCK_00485 5.7e-129 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 E hydrolase
PANGELCK_00486 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
PANGELCK_00487 3.4e-269 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PANGELCK_00488 5.2e-87 pat 2.3.1.183 M acetyltransferase
PANGELCK_00489 3.7e-285 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
PANGELCK_00491 1.1e-198 asd 1.2.1.11 E Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PANGELCK_00492 6.6e-173 dapA 4.3.3.7 E Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PANGELCK_00493 2.5e-124 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
PANGELCK_00494 0.0 smc D Required for chromosome condensation and partitioning
PANGELCK_00495 5.5e-79 S Protein of unknown function (DUF3278)
PANGELCK_00496 1e-22 WQ51_00220 K Helix-turn-helix domain
PANGELCK_00497 1.1e-197 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PANGELCK_00498 1.2e-36 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PANGELCK_00499 1.4e-43 paiA 2.3.1.57 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PANGELCK_00500 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PANGELCK_00502 7e-56 nrdD_1 1.1.98.6, 1.17.4.1 F Ribonucleoside-triphosphate reductase
PANGELCK_00503 2.6e-236 XK27_08130 K Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs
PANGELCK_00505 7.7e-83 S ECF-type riboflavin transporter, S component
PANGELCK_00506 2.6e-147 pdxK 2.7.1.35 H Belongs to the pyridoxine kinase family
PANGELCK_00507 9.8e-81 XK27_01265 S ECF-type riboflavin transporter, S component
PANGELCK_00508 4.3e-294 yfmM S abc transporter atp-binding protein
PANGELCK_00509 3.9e-254 noxE P NADH oxidase
PANGELCK_00510 1.6e-180 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
PANGELCK_00511 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PANGELCK_00512 3.9e-131 srtA 3.4.22.70 M Sortase (surface protein transpeptidase)
PANGELCK_00513 7e-71 yaeR E COG0346 Lactoylglutathione lyase and related lyases
PANGELCK_00514 8.7e-160 ypuA S secreted protein
PANGELCK_00515 1.2e-89 mntH P Mn2 and Fe2 transporters of the NRAMP family
PANGELCK_00516 2.4e-113 mntH P Mn2 and Fe2 transporters of the NRAMP family
PANGELCK_00517 4.4e-45 rpmE2 J 50S ribosomal protein L31
PANGELCK_00518 6.4e-168 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
PANGELCK_00519 9.3e-175 nrnA 3.1.13.3, 3.1.3.7 S domain protein
PANGELCK_00520 2.4e-152 gst O Glutathione S-transferase
PANGELCK_00521 1.1e-184 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
PANGELCK_00522 3e-110 tdk 2.7.1.21 F thymidine kinase
PANGELCK_00523 1.1e-190 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PANGELCK_00524 2.2e-143 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
PANGELCK_00525 3.6e-103 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
PANGELCK_00526 6.7e-229 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PANGELCK_00527 2.7e-177 ndpA S 37-kD nucleoid-associated bacterial protein
PANGELCK_00528 3.2e-99 pvaA M lytic transglycosylase activity
PANGELCK_00529 1.9e-290 yfiB1 V abc transporter atp-binding protein
PANGELCK_00530 0.0 XK27_10035 V abc transporter atp-binding protein
PANGELCK_00531 4.9e-298 dltA 6.1.1.13 Q Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PANGELCK_00532 8.1e-235 dltB M Membrane protein involved in D-alanine export
PANGELCK_00533 2.2e-35 dltC 6.1.1.13 IQ Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
PANGELCK_00534 4.5e-233 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
PANGELCK_00535 9.4e-91 G Citrate lyase beta subunit
PANGELCK_00536 5.3e-75 3.1.3.12 S hydrolases of the HAD superfamily
PANGELCK_00537 0.0 3.6.3.8 P cation transport ATPase
PANGELCK_00538 1.8e-89 T proteins involved in stress response, homologs of TerZ and
PANGELCK_00539 2e-76 T proteins involved in stress response, homologs of TerZ and
PANGELCK_00540 1.2e-90 T proteins involved in stress response, homologs of TerZ and
PANGELCK_00541 1.6e-165 yceH P Belongs to the TelA family
PANGELCK_00542 1.3e-197 yceG S Putative component of 'biosynthetic module'
PANGELCK_00543 5.7e-144 stiP J Phosphoribosyl transferase (PRTase)
PANGELCK_00544 1.8e-111 apt 2.4.2.22, 2.4.2.7 F TRSP domain C terminus to PRTase_2
PANGELCK_00545 0.0 pabB 2.6.1.85, 4.1.3.27, 4.1.3.38 EH component I
PANGELCK_00547 0.0 metE 2.1.1.14 E Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PANGELCK_00548 7.3e-166 metF 1.5.1.20 E reductase
PANGELCK_00549 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase
PANGELCK_00550 4.1e-93 panT S ECF transporter, substrate-specific component
PANGELCK_00551 4.5e-89 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
PANGELCK_00552 1.5e-113 coaB 4.1.1.36, 6.3.2.5 H Phosphopantothenate-cysteine ligase
PANGELCK_00553 0.0 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
PANGELCK_00554 9.4e-121 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PANGELCK_00555 1.9e-240 T PhoQ Sensor
PANGELCK_00556 2.3e-29 rpsT J Binds directly to 16S ribosomal RNA
PANGELCK_00557 4.4e-169 coaA 2.7.1.33 F Pantothenic acid kinase
PANGELCK_00558 4.1e-104 rsmC 2.1.1.172 J Methyltransferase small domain protein
PANGELCK_00559 5e-232 pdp 2.4.2.2, 2.4.2.4 F Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate
PANGELCK_00560 8.7e-111 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
PANGELCK_00561 7.4e-65 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
PANGELCK_00562 1.8e-190 tcsA S membrane
PANGELCK_00563 3.5e-280 xylG 3.6.3.17 S ABC transporter, ATP-binding protein
PANGELCK_00564 8.6e-177 yufP S Belongs to the binding-protein-dependent transport system permease family
PANGELCK_00565 2.3e-168 yufQ S Belongs to the binding-protein-dependent transport system permease family
PANGELCK_00566 5e-116 ycbL 3.1.2.6 S COG0491 Zn-dependent hydrolases, including glyoxylases
PANGELCK_00567 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
PANGELCK_00568 4.1e-78 ypmB S Protein conserved in bacteria
PANGELCK_00569 7e-212 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
PANGELCK_00570 1.1e-261 asnS 6.1.1.22 J Catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA
PANGELCK_00571 8.2e-19
PANGELCK_00572 2.3e-63 tdcF 3.5.99.10 J endoribonuclease L-PSP
PANGELCK_00573 2.6e-123 queC 6.3.4.20 F Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
PANGELCK_00574 4.8e-81 queD 4.1.2.50, 4.2.3.12 H synthase
PANGELCK_00575 5.5e-135 queE 1.97.1.4, 4.3.99.3 H Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
PANGELCK_00576 4.2e-94 queF 1.7.1.13 S Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily
PANGELCK_00577 1.3e-16 tcyB_2 P ABC transporter (permease)
PANGELCK_00579 1.6e-160 penP 3.5.2.6 V beta-lactamase
PANGELCK_00580 7.4e-35 F Belongs to the purine-cytosine permease (2.A.39) family
PANGELCK_00581 7.8e-114 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PANGELCK_00582 6.2e-123 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PANGELCK_00583 2e-72 ureE O Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
PANGELCK_00584 1.8e-101 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PANGELCK_00585 2.6e-88 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PANGELCK_00586 1e-92 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PANGELCK_00587 2.2e-40
PANGELCK_00588 1.1e-61 N domain, Protein
PANGELCK_00590 1.6e-28
PANGELCK_00591 1.7e-30
PANGELCK_00592 1.2e-43
PANGELCK_00593 3.2e-12
PANGELCK_00594 6e-112 S viral capsid
PANGELCK_00595 5.7e-60
PANGELCK_00596 5.7e-11
PANGELCK_00597 0.0 3.1.21.4 S Phage terminase large subunit (GpA)
PANGELCK_00598 1.4e-27 S gpW
PANGELCK_00599 4.4e-310 S Phage portal protein, lambda family
PANGELCK_00600 4.5e-215 S Peptidase family S49
PANGELCK_00601 4e-56 S Bacteriophage lambda head decoration protein D
PANGELCK_00602 3.5e-158 2.7.1.74, 2.7.1.76 F nucleoside 2-deoxyribosyltransferase
PANGELCK_00603 4.3e-79 tnpR L Resolvase, N terminal domain
PANGELCK_00604 0.0 L Tn3 transposase DDE domain
PANGELCK_00608 3.2e-39
PANGELCK_00611 1.4e-112 S hydrolase activity
PANGELCK_00613 2.3e-27 S Protein of unknown function (DUF2800)
PANGELCK_00614 1.5e-24
PANGELCK_00616 1.6e-49 bta 1.8.1.8 CO cell redox homeostasis
PANGELCK_00617 8.2e-59 L thioesterase
PANGELCK_00618 5.1e-142 S Macro domain protein
PANGELCK_00619 2.4e-50 trxA O Belongs to the thioredoxin family
PANGELCK_00620 1.7e-70 yccU S CoA-binding protein
PANGELCK_00621 1e-142 tatD L Hydrolase, tatd
PANGELCK_00622 7.1e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
PANGELCK_00623 2.1e-152 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
PANGELCK_00625 9.2e-161 rsgA 3.1.3.100 G One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
PANGELCK_00626 7.8e-120 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
PANGELCK_00627 1.9e-115 thiN 2.7.6.2 H thiamine pyrophosphokinase
PANGELCK_00628 3.8e-171 rmuC S RmuC domain protein
PANGELCK_00629 1.2e-177 cbf S 3'-5' exoribonuclease yhaM
PANGELCK_00630 4e-142 purR 2.4.2.7 F operon repressor
PANGELCK_00631 2.3e-69 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PANGELCK_00632 3.9e-81 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
PANGELCK_00633 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PANGELCK_00634 7.1e-181 gap 1.2.1.12 C Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain
PANGELCK_00635 3.3e-124
PANGELCK_00636 5.8e-222 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
PANGELCK_00637 3e-87 S Fusaric acid resistance protein-like
PANGELCK_00638 2.5e-62 glnR K Transcriptional regulator
PANGELCK_00639 5.2e-264 glnA 6.3.1.2 E glutamine synthetase
PANGELCK_00640 8e-114 pscB M CHAP domain protein
PANGELCK_00641 0.0 rnjA S An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
PANGELCK_00642 1.5e-33 ykzG S Belongs to the UPF0356 family
PANGELCK_00643 4.6e-115 yeaZ 2.3.1.234 O COG1214, inactive homolog of metal-dependent proteases
PANGELCK_00644 5.9e-71 rimI 2.3.1.128 K This enzyme acetylates the N-terminal alanine of ribosomal protein S18
PANGELCK_00645 2.1e-185 tsaD 2.3.1.234 O Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PANGELCK_00646 2.2e-112 azlC E AzlC protein
PANGELCK_00647 7.5e-47 azlD S branched-chain amino acid
PANGELCK_00648 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
PANGELCK_00649 6.1e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
PANGELCK_00650 1.9e-153 rnhC 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PANGELCK_00651 9.3e-15 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
PANGELCK_00652 2.4e-90 cvpA S toxin biosynthetic process
PANGELCK_00653 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
PANGELCK_00654 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
PANGELCK_00656 7.6e-35
PANGELCK_00659 8.3e-218 mutY L A G-specific adenine glycosylase
PANGELCK_00660 7.2e-42 XK27_05745
PANGELCK_00661 3e-47 rpsF J Binds together with S18 to 16S ribosomal RNA
PANGELCK_00662 2.5e-81 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PANGELCK_00663 6.3e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PANGELCK_00665 1.9e-121 XK27_01040 S Protein of unknown function (DUF1129)
PANGELCK_00666 1e-168 corA P COG0598 Mg2 and Co2 transporters
PANGELCK_00667 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PANGELCK_00671 8e-32 blpT
PANGELCK_00672 1.6e-146 V 'abc transporter, ATP-binding protein
PANGELCK_00674 2e-186 pepP 3.4.11.9, 3.4.13.9 E Belongs to the peptidase M24B family
PANGELCK_00675 3.3e-85 comEB 3.5.4.12 F ComE operon protein 2
PANGELCK_00676 7.1e-98 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PANGELCK_00677 1.7e-61 yqhY S protein conserved in bacteria
PANGELCK_00678 8.1e-73 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PANGELCK_00679 7.5e-180 scrR K Transcriptional regulator
PANGELCK_00680 9.9e-285 scrB 3.2.1.26, 3.2.1.80 GH32 G invertase
PANGELCK_00681 0.0 scrA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_00682 6.5e-170 scrK 2.7.1.2, 2.7.1.4 GK Fructokinase
PANGELCK_00683 7.4e-188 manA 5.3.1.8 G mannose-6-phosphate isomerase
PANGELCK_00685 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
PANGELCK_00686 5.5e-197 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PANGELCK_00687 2.8e-196 aroF 2.5.1.54 E Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
PANGELCK_00688 1.7e-60 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
PANGELCK_00689 3.2e-182 alr 5.1.1.1, 5.1.1.5 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PANGELCK_00690 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PANGELCK_00694 2.9e-31 yozG K Transcriptional regulator
PANGELCK_00696 3e-170 ansA 3.5.1.1 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D
PANGELCK_00697 6.8e-259 XK27_03190 S hydrolases of the HAD superfamily
PANGELCK_00698 5.7e-113 yebC M Membrane
PANGELCK_00699 2.6e-308 KT response to antibiotic
PANGELCK_00700 1.5e-74 XK27_02470 K LytTr DNA-binding domain
PANGELCK_00701 5.3e-119 liaI S membrane
PANGELCK_00702 8.7e-78 mccF V LD-carboxypeptidase
PANGELCK_00703 5.3e-43 S Sugar efflux transporter for intercellular exchange
PANGELCK_00704 4.4e-194 mccF V LD-carboxypeptidase
PANGELCK_00705 3.9e-298 O MreB/Mbl protein
PANGELCK_00707 5.8e-146 V Psort location CytoplasmicMembrane, score
PANGELCK_00710 2e-13
PANGELCK_00711 5.9e-228 dcuS 2.7.13.3 T protein histidine kinase activity
PANGELCK_00712 5.4e-232 2.7.13.3 T protein histidine kinase activity
PANGELCK_00713 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
PANGELCK_00714 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
PANGELCK_00715 6.2e-126 S Protein of unknown function (DUF554)
PANGELCK_00716 8.1e-134 ecsA_2 V abc transporter atp-binding protein
PANGELCK_00717 1.3e-277 XK27_00765
PANGELCK_00718 2.2e-140 proB 2.7.2.11 E Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PANGELCK_00719 5.5e-223 proA 1.2.1.41 E Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PANGELCK_00720 4.7e-56 yhaI J Membrane
PANGELCK_00721 1.1e-52 yhaI S Protein of unknown function (DUF805)
PANGELCK_00722 3e-58 yhaI J Protein of unknown function (DUF805)
PANGELCK_00724 2.3e-97
PANGELCK_00725 3.9e-173 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
PANGELCK_00726 2.4e-45 ftsL D cell division protein FtsL
PANGELCK_00727 0.0 ftsI 3.4.16.4 M penicillin-binding protein
PANGELCK_00728 1.1e-184 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PANGELCK_00729 1e-219 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
PANGELCK_00731 7.9e-252 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
PANGELCK_00732 2.5e-60 yutD J protein conserved in bacteria
PANGELCK_00733 1.8e-223 rlmN 2.1.1.192 J Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
PANGELCK_00734 1.8e-90 XK27_09885 V Glycopeptide antibiotics resistance protein
PANGELCK_00737 0.0 mdlA V abc transporter atp-binding protein
PANGELCK_00738 0.0 mdlB V abc transporter atp-binding protein
PANGELCK_00747 1.8e-44 spiA K sequence-specific DNA binding
PANGELCK_00748 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
PANGELCK_00749 2.8e-149 gla U Belongs to the MIP aquaporin (TC 1.A.8) family
PANGELCK_00750 1.3e-98 V CAAX protease self-immunity
PANGELCK_00751 2.8e-137 cppA E CppA N-terminal
PANGELCK_00752 2.8e-171 ampC V COG1680 Beta-lactamase class C and other penicillin binding proteins
PANGELCK_00754 8.4e-73 yjcF S COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PANGELCK_00755 1.7e-142 cah 4.2.1.1 P carbonic anhydrase
PANGELCK_00756 0.0 pflB 2.3.1.54 C formate acetyltransferase'
PANGELCK_00757 7.3e-203 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PANGELCK_00758 8e-35
PANGELCK_00759 2e-152 yxeM ET ABC-type amino acid transport signal transduction systems, periplasmic component domain
PANGELCK_00760 4e-162 yxeN P ABC transporter (Permease
PANGELCK_00761 5.2e-128 tcyN 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_00762 8.6e-10 S Protein of unknown function (DUF4059)
PANGELCK_00763 2.1e-171 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
PANGELCK_00764 5.6e-92 rsmD 2.1.1.171 L Methyltransferase
PANGELCK_00765 1.7e-87 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PANGELCK_00766 1.2e-186 ylbL T Belongs to the peptidase S16 family
PANGELCK_00767 5.1e-181 yhcC S radical SAM protein
PANGELCK_00768 4e-93 ytqB 2.1.1.176 J (SAM)-dependent
PANGELCK_00770 0.0 yjcE P NhaP-type Na H and K H antiporters
PANGELCK_00771 4.6e-25
PANGELCK_00773 5.1e-142 modF 3.6.3.21, 3.6.3.34 P abc transporter atp-binding protein
PANGELCK_00774 7.1e-237 hlyX S COG1253 Hemolysins and related proteins containing CBS domains
PANGELCK_00775 1.8e-08 MU outer membrane autotransporter barrel domain protein
PANGELCK_00776 1.5e-157 pflA 1.97.1.4 C Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PANGELCK_00778 3.4e-118 L Helix-turn-helix domain
PANGELCK_00779 3.2e-145 L Integrase core domain protein
PANGELCK_00780 2.6e-74 XK27_03180 T universal stress protein
PANGELCK_00781 1e-237 alaA 2.6.1.2, 2.6.1.66 E Aminotransferase
PANGELCK_00782 8.1e-140 codY K DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
PANGELCK_00783 2.2e-99 pncA Q isochorismatase
PANGELCK_00784 1.9e-147 hlpA M Belongs to the NlpA lipoprotein family
PANGELCK_00785 9.1e-92 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PANGELCK_00786 1.4e-291 ascB 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PANGELCK_00787 9.6e-217 M lipopolysaccharide 3-alpha-galactosyltransferase activity
PANGELCK_00788 1.8e-156 H COG0463 Glycosyltransferases involved in cell wall biogenesis
PANGELCK_00789 2e-191 M A stabilizing protein that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon. Stabilizes the glycosylation activity of Gtf1
PANGELCK_00790 6.9e-233 2.4.1.52 GT4 M An N-acetylglucosaminyl transferase that is part of the accessory SecA2 SecY2 system specifically required to export serine-rich repeat cell wall proteins usually encoded upstream in the same operon
PANGELCK_00791 1.4e-47 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PANGELCK_00792 5.5e-267 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
PANGELCK_00793 5.6e-272 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
PANGELCK_00794 3.3e-75 4.2.1.6 M Domain of unknown function (DUF4433)
PANGELCK_00795 2.8e-52 comEA 2.4.1.21 GT5 L photosystem II stabilization
PANGELCK_00796 4.7e-28 M LysM domain
PANGELCK_00797 1.1e-60
PANGELCK_00798 3.9e-190 bdhA 1.1.1.303, 1.1.1.4 E Dehydrogenase
PANGELCK_00799 3.1e-151 yicL EG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily
PANGELCK_00800 5.1e-98 yqeG S hydrolase of the HAD superfamily
PANGELCK_00801 4.6e-213 yqeH S in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis
PANGELCK_00802 7.7e-49 yhbY J RNA-binding protein
PANGELCK_00803 1.2e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PANGELCK_00804 2.9e-105 nadD 2.7.6.3, 2.7.7.18 H HD superfamily hydrolase involved in NAD metabolism
PANGELCK_00805 3e-87 entB 3.5.1.19 Q Isochorismatase family
PANGELCK_00806 7.7e-58 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
PANGELCK_00807 3.8e-139 yqeM Q Methyltransferase domain protein
PANGELCK_00808 4.3e-200 ylbM S Belongs to the UPF0348 family
PANGELCK_00809 5.1e-173 L Integrase
PANGELCK_00810 1.7e-38 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
PANGELCK_00811 1e-43 yoeB S Addiction module toxin, Txe YoeB family
PANGELCK_00813 0.0 clpL O ATP-dependent Clp protease ATP-binding subunit
PANGELCK_00815 1.6e-103
PANGELCK_00818 1e-72 hit FG Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases
PANGELCK_00819 1.1e-130 ecsA V abc transporter atp-binding protein
PANGELCK_00820 1.6e-175 ecsB U Bacterial ABC transporter protein EcsB
PANGELCK_00821 7.1e-152 ytmP 2.7.1.89 M Phosphotransferase
PANGELCK_00822 1.5e-120 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
PANGELCK_00824 1.3e-221 ytfP S Flavoprotein
PANGELCK_00825 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PANGELCK_00826 9.6e-64 XK27_02560 S cog cog2151
PANGELCK_00827 9.1e-42 WQ51_02910 S Protein of unknown function, DUF536
PANGELCK_00828 3.2e-09 dnaQ 2.7.7.7 L DNA polymerase III
PANGELCK_00829 1.3e-84 dnaQ 2.7.7.7 L DNA polymerase III
PANGELCK_00830 1.9e-127 K transcriptional regulator, MerR family
PANGELCK_00831 0.0 V ABC transporter (Permease
PANGELCK_00832 9.5e-124 V abc transporter atp-binding protein
PANGELCK_00834 8.7e-42 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PANGELCK_00835 1.4e-47
PANGELCK_00836 2.9e-50
PANGELCK_00837 4.4e-46
PANGELCK_00839 6.2e-76
PANGELCK_00840 0.0
PANGELCK_00841 0.0 bcsA 2.4.1.12 GT2 M COG1215 Glycosyltransferases, probably involved in cell wall biogenesis
PANGELCK_00842 1.4e-147 2.4.1.83 GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PANGELCK_00844 1.1e-160 T Diguanylate cyclase
PANGELCK_00845 2.2e-35 pfkB 2.7.1.11, 2.7.1.56 H Belongs to the carbohydrate kinase PfkB family. LacC subfamily
PANGELCK_00846 2e-60 fruR K transcriptional
PANGELCK_00847 4.2e-28 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
PANGELCK_00848 3.7e-45
PANGELCK_00849 7.2e-49
PANGELCK_00850 0.0 L AAA ATPase domain
PANGELCK_00851 0.0 3.6.4.12 L UvrD/REP helicase N-terminal domain
PANGELCK_00852 0.0 ctpE P E1-E2 ATPase
PANGELCK_00853 2.6e-59
PANGELCK_00854 1e-18 S Bacteriocin (Lactococcin_972)
PANGELCK_00855 0.0 S bacteriocin-associated integral membrane protein
PANGELCK_00856 1.9e-118 yujD V ABC transporter
PANGELCK_00857 9.8e-41 pchB 2.5.1.19, 4.2.1.10, 4.2.99.21, 5.4.99.5 E Chorismate mutase
PANGELCK_00858 8.2e-257 trpE 4.1.3.27 EH Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PANGELCK_00859 3.3e-103 trpG 2.4.2.18, 2.6.1.85, 4.1.3.27 EH anthranilate
PANGELCK_00860 8.7e-179 trpD 2.4.2.18, 4.1.3.27 F Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PANGELCK_00861 2.3e-131 trpC 4.1.1.48, 5.3.1.24 E Belongs to the TrpC family
PANGELCK_00862 4.8e-97 trpF 4.1.1.48, 4.2.1.160, 4.2.1.20, 5.3.1.24 E belongs to the TrpF family
PANGELCK_00863 6.4e-229 trpB 4.2.1.20, 5.3.1.24 E The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
PANGELCK_00864 1.9e-141 trpA 4.2.1.20 E The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate
PANGELCK_00869 4.2e-74 copY K negative regulation of transcription, DNA-templated
PANGELCK_00870 0.0 copA 3.6.3.54 P P-type ATPase
PANGELCK_00871 2.7e-31 copZ 2.7.7.77 P Heavy metal-associated domain protein
PANGELCK_00872 9.7e-34 K Transcriptional regulator C-terminal region
PANGELCK_00873 2.2e-83 V ABC transporter
PANGELCK_00874 2.5e-56
PANGELCK_00875 6.7e-193 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
PANGELCK_00876 3.9e-114 papP P ABC transporter (Permease
PANGELCK_00877 3e-106 P ABC transporter (Permease
PANGELCK_00878 3.4e-135 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_00879 9.7e-155 cjaA ET ABC transporter substrate-binding protein
PANGELCK_00883 6.6e-254 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
PANGELCK_00884 1.8e-116 ywaF S Integral membrane protein (intg_mem_TP0381)
PANGELCK_00885 3.9e-40
PANGELCK_00887 1.4e-34
PANGELCK_00891 5.8e-30
PANGELCK_00895 3.4e-08
PANGELCK_00896 3.9e-276 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
PANGELCK_00897 3e-187 pfkA 2.7.1.11 F Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis
PANGELCK_00898 0.0 dnaE 2.7.7.7 L DNA polymerase
PANGELCK_00899 7e-112 leuD 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PANGELCK_00900 2.8e-276 leuC 4.2.1.33, 4.2.1.35 E Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PANGELCK_00901 4.3e-189 leuB 1.1.1.85 CE Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
PANGELCK_00902 8.4e-290 leuA 2.3.3.13 E Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PANGELCK_00903 3.6e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PANGELCK_00904 1.8e-178 pyrD 1.3.1.14, 1.3.98.1 F Catalyzes the conversion of dihydroorotate to orotate
PANGELCK_00906 6.3e-39 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
PANGELCK_00907 9.9e-95 ypmS S Protein conserved in bacteria
PANGELCK_00908 9.6e-158 ypmR E COG2755 Lysophospholipase L1 and related esterases
PANGELCK_00909 3.4e-144 DegV S DegV family
PANGELCK_00910 2.5e-300 recN L May be involved in recombinational repair of damaged DNA
PANGELCK_00911 2.4e-72 argR K Regulates arginine biosynthesis genes
PANGELCK_00912 7.7e-149 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
PANGELCK_00913 2.8e-157 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
PANGELCK_00914 4.6e-29 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PANGELCK_00915 1.4e-232 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
PANGELCK_00917 1.1e-118 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PANGELCK_00918 5e-125 dnaD
PANGELCK_00919 6e-182 metA 2.3.1.46 E Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
PANGELCK_00920 6.4e-93 apt 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
PANGELCK_00921 0.0 recJ L Single-strand DNA-specific exonuclease, C terminal domain
PANGELCK_00922 1.3e-64 GnaT 2.5.1.16 K acetyltransferase
PANGELCK_00923 1.3e-38 Q Methyltransferase domain
PANGELCK_00924 3.1e-136 XK27_05435 1.1.1.100 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PANGELCK_00925 2.7e-174 rnz 3.1.26.11 S Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
PANGELCK_00926 1.5e-112 galT 2.7.7.12 G UDPglucose--hexose-1-phosphate uridylyltransferase
PANGELCK_00927 5.5e-245 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PANGELCK_00928 8.4e-236 rodA D Belongs to the SEDS family
PANGELCK_00929 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00930 8.5e-163 L High confidence in function and specificity
PANGELCK_00931 2e-42 mccF V LD-carboxypeptidase
PANGELCK_00932 3.5e-46 L COG3547 Transposase and inactivated derivatives
PANGELCK_00933 1.6e-104 L COG3547 Transposase and inactivated derivatives
PANGELCK_00934 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00935 0.0 2.4.1.5 GH13 M KxYKxGKxW signal domain protein
PANGELCK_00936 5.2e-179 XK27_08075 M glycosyl transferase family 2
PANGELCK_00937 9.5e-98 S Carbohydrate-binding domain-containing protein Cthe_2159
PANGELCK_00938 3.7e-145 P molecular chaperone
PANGELCK_00939 3.8e-93 XK27_05505 S Psort location CytoplasmicMembrane, score
PANGELCK_00941 4.1e-50 hisE 3.5.4.19, 3.6.1.31, 5.3.1.16 E phosphoribosyl-ATP diphosphatase activity
PANGELCK_00942 1.8e-59 hisI 3.5.4.19, 3.5.4.25, 3.6.1.31, 5.3.1.16 E Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PANGELCK_00943 4e-136 hisF 3.5.4.19, 3.6.1.31 E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
PANGELCK_00944 1.2e-129 hisA 5.3.1.16 E 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PANGELCK_00945 1.6e-111 hisH E IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PANGELCK_00946 3.9e-107 hisB 1.1.1.23, 2.6.1.9, 3.1.3.15, 4.2.1.19 E imidazoleglycerol-phosphate dehydratase
PANGELCK_00947 7.8e-233 hisD 1.1.1.23, 1.1.1.308 E Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PANGELCK_00948 8e-117 hisG 2.4.2.17 E Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
PANGELCK_00949 9e-181 hisZ 2.4.2.17, 6.1.1.21 E Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
PANGELCK_00950 1.9e-192 hisC 2.6.1.9 E Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PANGELCK_00951 5.9e-59 XK27_08085
PANGELCK_00952 1.4e-146 XK27_08080 3.1.1.53 G Exopolysaccharide biosynthesis protein
PANGELCK_00953 1.3e-136 hisK 3.1.3.15 E Histidinol phosphatase and related hydrolases of the PHP family
PANGELCK_00954 3.7e-114 ylfI S tigr01906
PANGELCK_00955 1.2e-140 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
PANGELCK_00956 1.1e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
PANGELCK_00957 2.5e-214 hemN H Involved in the biosynthesis of porphyrin-containing compound
PANGELCK_00958 5.4e-29 KT response to antibiotic
PANGELCK_00960 1.3e-204 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
PANGELCK_00961 1.9e-112 rmlC 1.1.1.133, 5.1.3.13 M Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose
PANGELCK_00962 2.4e-161 rfbA 2.7.7.24 M Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
PANGELCK_00963 1.9e-258 S phospholipase Carboxylesterase
PANGELCK_00964 2.1e-199 yurR 1.4.5.1 E oxidoreductase
PANGELCK_00965 9.7e-144 zupT P Mediates zinc uptake. May also transport other divalent cations
PANGELCK_00966 2e-146 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PANGELCK_00967 1.2e-123 trmK 2.1.1.217 S SAM-dependent methyltransferase
PANGELCK_00968 1.8e-66 gtrA S GtrA-like protein
PANGELCK_00969 5.7e-250 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PANGELCK_00970 5.4e-162 ybbR S Protein conserved in bacteria
PANGELCK_00971 7.9e-149 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PANGELCK_00972 2.4e-253 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain protein
PANGELCK_00973 1.1e-147 cobQ S glutamine amidotransferase
PANGELCK_00974 0.0 mprF 2.3.2.3 J Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
PANGELCK_00975 9.7e-132 pip 1.11.1.10 S Alpha beta hydrolase
PANGELCK_00976 2.7e-39 MA20_06245 S yiaA/B two helix domain
PANGELCK_00977 0.0 uup S abc transporter atp-binding protein
PANGELCK_00978 3.1e-113 udk 2.7.1.48 F Cytidine monophosphokinase
PANGELCK_00979 1.1e-176 yfmL 3.6.4.13 L DEAD DEAH box helicase
PANGELCK_00980 5.4e-225 XK27_05680 6.3.2.2, 6.3.2.4 M carbamoylphosphate synthase large subunit
PANGELCK_00981 5.1e-152 XK27_05675 S Esterase
PANGELCK_00982 6.1e-162 XK27_05670 S Putative esterase
PANGELCK_00983 6.6e-265 gapN 1.2.1.9 C Belongs to the aldehyde dehydrogenase family
PANGELCK_00984 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
PANGELCK_00985 3e-38 ptsH G phosphocarrier protein Hpr
PANGELCK_00986 1.6e-216 icd 1.1.1.42 C Isocitrate dehydrogenase
PANGELCK_00987 6.9e-209 citZ 2.3.3.1 C Belongs to the citrate synthase family
PANGELCK_00988 0.0 acnA 4.2.1.3 C Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PANGELCK_00989 2.2e-34 nrdH O Glutaredoxin
PANGELCK_00990 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PANGELCK_00991 4.2e-183 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PANGELCK_00992 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PANGELCK_00993 1.9e-137 divIVA D Cell division initiation protein
PANGELCK_00994 7.7e-138 ylmH S conserved protein, contains S4-like domain
PANGELCK_00995 3.8e-30 yggT D integral membrane protein
PANGELCK_00996 3.4e-90 sepF D cell septum assembly
PANGELCK_00997 2.4e-119 ylmE S Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PANGELCK_00998 3.3e-234 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PANGELCK_00999 3.5e-223 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
PANGELCK_01000 4.9e-138 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
PANGELCK_01001 4.4e-197 murG 2.4.1.227 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PANGELCK_01002 6.9e-248 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PANGELCK_01004 0.0 typA T GTP-binding protein TypA
PANGELCK_01005 3e-176 glk 2.7.1.2 G Glucokinase
PANGELCK_01006 4.2e-27 yqgQ S protein conserved in bacteria
PANGELCK_01007 3.4e-79 perR P Belongs to the Fur family
PANGELCK_01008 2.9e-77 dps P Belongs to the Dps family
PANGELCK_01009 1.1e-102 pilD 3.4.23.43 NOU Type II secretory pathway prepilin signal peptidase PulO and related peptidases
PANGELCK_01010 2.9e-164 3.5.2.6 V D-alanyl-D-alanine carboxypeptidase
PANGELCK_01011 1e-110 sodA 1.15.1.1 C radicals which are normally produced within the cells and which are toxic to biological systems
PANGELCK_01012 5.9e-183 holA 2.7.7.7 L DNA polymerase III delta subunit
PANGELCK_01013 0.0 ppc 4.1.1.31 H Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PANGELCK_01014 1.2e-62 S Domain of unknown function (DUF4430)
PANGELCK_01015 9.2e-73 S Psort location CytoplasmicMembrane, score
PANGELCK_01016 1.6e-126 sitB 3.6.3.35 P ABC transporter, ATP-binding protein
PANGELCK_01017 2.3e-132 mtsC P ABC-type Mn2 Zn2 transport systems, permease components
PANGELCK_01018 3e-170 sitA P Belongs to the bacterial solute-binding protein 9 family
PANGELCK_01019 1.9e-118 sirR K iron dependent repressor
PANGELCK_01020 4e-135 htpX O Belongs to the peptidase M48B family
PANGELCK_01021 7.7e-92 lemA S LemA family
PANGELCK_01022 1.2e-172 spd F DNA RNA non-specific endonuclease
PANGELCK_01023 0.0 2.4.1.21 GT5 M Right handed beta helix region
PANGELCK_01024 3.1e-135 S double-stranded DNA endodeoxyribonuclease activity
PANGELCK_01025 3.6e-304 hsdM 2.1.1.72 V type I restriction-modification system
PANGELCK_01026 1.8e-128 S Protein conserved in bacteria
PANGELCK_01027 5.5e-109
PANGELCK_01028 2.4e-71 3.1.21.3 V Type I restriction modification DNA specificity domain
PANGELCK_01030 9.5e-174 S Bacteriophage abortive infection AbiH
PANGELCK_01031 0.0 hsdR 3.1.21.3 L Subunit R is required for both nuclease and ATPase activities, but not for modification
PANGELCK_01032 1.7e-45 K Helix-turn-helix domain
PANGELCK_01033 3.5e-132 sdh 1.1.1.276, 1.1.1.313, 1.1.1.381 S Belongs to the short-chain dehydrogenases reductases (SDR) family
PANGELCK_01034 1.7e-202 MA20_36090 S Protein of unknown function (DUF2974)
PANGELCK_01035 2e-112 1.14.14.5 C COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PANGELCK_01036 5.2e-153 5.2.1.8 G hydrolase
PANGELCK_01037 3e-26 P Hemerythrin HHE cation binding domain protein
PANGELCK_01038 5.8e-140 XK27_00880 3.5.1.28 M Glycosyl hydrolase, family 25
PANGELCK_01039 1.8e-81 ybaK S Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
PANGELCK_01040 1.2e-114 pgm6 5.4.2.11, 5.4.2.12 G Phosphoglycerate mutase
PANGELCK_01042 7.5e-174 S hydrolase
PANGELCK_01043 8.4e-23
PANGELCK_01044 7.2e-141 M LysM domain
PANGELCK_01045 9.2e-286 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
PANGELCK_01046 5.1e-16
PANGELCK_01047 2.8e-11
PANGELCK_01048 1.1e-232 mntH P H( )-stimulated, divalent metal cation uptake system
PANGELCK_01049 1.1e-33 XK27_12190 S protein conserved in bacteria
PANGELCK_01051 2.5e-87 bioY S biotin synthase
PANGELCK_01052 7.5e-252 yegQ O Peptidase U32
PANGELCK_01053 8.9e-178 yegQ O Peptidase U32
PANGELCK_01055 1.9e-66 ytxH S General stress protein
PANGELCK_01056 3.7e-08 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
PANGELCK_01057 1.6e-143 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PANGELCK_01058 1.6e-166 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
PANGELCK_01059 2.2e-41 pspC KT PspC domain
PANGELCK_01060 2.3e-83 ydcK S Belongs to the SprT family
PANGELCK_01061 0.0 yhgF K Transcriptional accessory protein
PANGELCK_01063 1.6e-155 XK27_03015 S permease
PANGELCK_01064 2.9e-148 ycgQ S TIGR03943 family
PANGELCK_01065 2.4e-171 S CRISPR-associated protein Csn2 subfamily St
PANGELCK_01066 3.1e-53 cas2 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PANGELCK_01067 9.3e-172 cas1 L CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
PANGELCK_01068 0.0 cas9 L CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
PANGELCK_01069 1.9e-276 sulP P Sulfate permease and related transporters (MFS superfamily)
PANGELCK_01070 6.4e-100
PANGELCK_01071 6.2e-114 estA E GDSL-like Lipase/Acylhydrolase
PANGELCK_01072 4e-94 S CAAX protease self-immunity
PANGELCK_01073 1.1e-51
PANGELCK_01075 6.3e-63 yqeB S Pyrimidine dimer DNA glycosylase
PANGELCK_01076 6.4e-61 S Protein of unknown function (DUF1722)
PANGELCK_01077 2.6e-20 M Bacterial lipoprotein
PANGELCK_01078 5.8e-10
PANGELCK_01079 1.2e-127 V CAAX protease self-immunity
PANGELCK_01080 6e-46
PANGELCK_01081 6.8e-75 K TetR family transcriptional regulator
PANGELCK_01082 4.9e-81 Q Methyltransferase domain
PANGELCK_01083 1.7e-144 acoC 2.3.1.12, 2.3.1.61 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PANGELCK_01084 3e-174 acoB C dehydrogenase E1 component
PANGELCK_01085 1.8e-166 acoA C Acetoin dehydrogenase E1 component subunit alpha
PANGELCK_01086 2.8e-172 pdhD 1.8.1.4 C Dehydrogenase
PANGELCK_01087 7.8e-10 S CsbD-like
PANGELCK_01088 7.2e-31 S Membrane
PANGELCK_01089 4.7e-172 S Domain of unknown function (DUF389)
PANGELCK_01090 2.5e-158 yegS 2.7.1.107 I Diacylglycerol kinase
PANGELCK_01091 7.1e-124 ybbA S Putative esterase
PANGELCK_01092 2.5e-173 fatB P COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component
PANGELCK_01093 8.3e-134 fecE 3.6.3.34 HP ABC transporter
PANGELCK_01094 6.5e-153 fecD P Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PANGELCK_01095 5e-123 V CAAX protease self-immunity
PANGELCK_01096 1.3e-148 S Domain of unknown function (DUF4300)
PANGELCK_01097 1.2e-94 tetR K transcriptional regulator
PANGELCK_01098 7.3e-282 norB P Major facilitator superfamily
PANGELCK_01099 4.1e-21 S Domain of unknown function (DUF4767)
PANGELCK_01101 9.9e-104 cutC P Participates in the control of copper homeostasis
PANGELCK_01102 1.9e-134 S CAAX amino terminal protease family
PANGELCK_01103 2.1e-97 ypgQ F HD superfamily hydrolase
PANGELCK_01104 5.2e-96 XK27_08140 K Bacterial regulatory proteins, tetR family
PANGELCK_01105 1.9e-150 yitS S EDD domain protein, DegV family
PANGELCK_01106 3.8e-202 yeaN P transporter
PANGELCK_01107 2.9e-131 S Domain of unknown function (DUF4336)
PANGELCK_01108 1.4e-131 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PANGELCK_01109 1.7e-12
PANGELCK_01110 7.7e-297 V ABC transporter transmembrane region
PANGELCK_01111 1.9e-127 bcrA V abc transporter atp-binding protein
PANGELCK_01112 2e-116 S ABC-type transport system involved in multi-copper enzyme maturation, permease component
PANGELCK_01113 5.7e-112 K Bacterial regulatory proteins, tetR family
PANGELCK_01114 1.5e-36 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PANGELCK_01115 5.9e-55
PANGELCK_01116 8.7e-60
PANGELCK_01117 1.1e-49
PANGELCK_01118 1e-257 yheS_2 S ATPase components of ABC transporters with duplicated ATPase domains
PANGELCK_01119 2e-217 EGP Transmembrane secretion effector
PANGELCK_01120 4.3e-22
PANGELCK_01121 7.5e-66 yvbK 3.1.3.25 K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
PANGELCK_01122 4.5e-18 K Psort location Cytoplasmic, score 8.87
PANGELCK_01123 4.4e-52 K TfoX N-terminal domain
PANGELCK_01124 5.2e-128 S CAAX protease self-immunity
PANGELCK_01125 1.7e-235 S the current gene model (or a revised gene model) may contain a frame shift
PANGELCK_01126 1.3e-85 XK27_12525 S hmm pf01594
PANGELCK_01128 7.8e-29 S the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts
PANGELCK_01129 2.7e-152 xtmB S phage Terminase large subunit
PANGELCK_01130 2.5e-138 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_01131 1e-29 atp9 1.6.5.3 C ATP hydrolysis coupled proton transport
PANGELCK_01133 2.7e-115 T response regulator
PANGELCK_01134 1.5e-104 2.7.6.5 S Region found in RelA / SpoT proteins
PANGELCK_01135 3e-22
PANGELCK_01136 2.7e-88 L Recombinase
PANGELCK_01138 2.3e-251 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PANGELCK_01139 2.7e-97 mip S hydroperoxide reductase activity
PANGELCK_01140 2.5e-200 I acyl-CoA dehydrogenase
PANGELCK_01141 5.3e-154 ydiA P C4-dicarboxylate transporter malic acid transport protein
PANGELCK_01142 8.3e-244 msrR K Transcriptional regulator
PANGELCK_01143 1.4e-153 pheA 4.2.1.51 E Prephenate dehydratase
PANGELCK_01144 2.7e-77 aroK 1.1.1.25, 2.7.1.71, 4.2.1.10, 4.2.3.4 F Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PANGELCK_01145 1.6e-233 aroA 1.3.1.12, 1.3.1.43, 2.5.1.19 E Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
PANGELCK_01146 1.2e-166 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily
PANGELCK_01147 1.2e-52 yheA S Belongs to the UPF0342 family
PANGELCK_01148 7.3e-203 tyrA 1.3.1.12, 1.3.1.43 E prephenate dehydrogenase
PANGELCK_01149 2.2e-218 aroC 4.2.3.5 E Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PANGELCK_01150 3.8e-201 aroB 2.7.1.71, 4.2.3.4 E Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PANGELCK_01151 1.2e-152 aroE 1.1.1.25 E Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PANGELCK_01152 3.4e-118 aroD 1.1.1.25, 4.2.1.10 E Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate
PANGELCK_01153 1.9e-214 ywbD 2.1.1.191 J Methyltransferase
PANGELCK_01154 0.0 ltaS 2.7.8.20 M Belongs to the LTA synthase family
PANGELCK_01155 1.2e-25 WQ51_00785
PANGELCK_01156 7.4e-247 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
PANGELCK_01157 7.9e-79 yueI S Protein of unknown function (DUF1694)
PANGELCK_01158 2.6e-200 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
PANGELCK_01159 3.3e-200 yyaQ S YjbR
PANGELCK_01160 1.9e-181 ccpA K Catabolite control protein A
PANGELCK_01161 5.4e-195 pepQ 3.4.13.9 E Belongs to the peptidase M24B family
PANGELCK_01162 1.3e-63 yugI 5.3.1.9 J RNA binding protein, contains ribosomal protein S1 domain
PANGELCK_01163 7.6e-274 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PANGELCK_01164 1.9e-80 smpB O the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
PANGELCK_01165 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
PANGELCK_01166 2e-33 secG U Preprotein translocase subunit SecG
PANGELCK_01167 5.9e-222 mdtG EGP Major facilitator Superfamily
PANGELCK_01168 3.4e-90 coaE 2.7.1.24, 3.2.2.23, 4.2.99.18 GH23 H Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
PANGELCK_01169 9.3e-147 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
PANGELCK_01170 4.4e-166 era M An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PANGELCK_01171 4.4e-65 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
PANGELCK_01172 1.3e-87 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PANGELCK_01173 7.7e-49 licT K antiterminator
PANGELCK_01174 7.4e-83 licT K antiterminator
PANGELCK_01175 1.3e-105 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PANGELCK_01176 0.0 pbp2b 3.4.16.4 M penicillin-binding protein
PANGELCK_01177 5.8e-144 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PANGELCK_01178 6.3e-154 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PANGELCK_01179 6.1e-148 I Alpha/beta hydrolase family
PANGELCK_01180 6.6e-08
PANGELCK_01181 0.0 feoB P transporter of a GTP-driven Fe(2 ) uptake system
PANGELCK_01182 2.9e-76 feoA P FeoA domain protein
PANGELCK_01183 6.4e-131 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_01184 5.8e-118 WQ51_01820 P Binding-protein-dependent transport system inner membrane component
PANGELCK_01185 1e-34 ykuJ S protein conserved in bacteria
PANGELCK_01186 1.4e-181 argF 2.1.3.3 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PANGELCK_01187 0.0 clpE O Belongs to the ClpA ClpB family
PANGELCK_01188 5.1e-86 mutT 3.5.4.33, 3.6.1.13, 3.6.1.55 L Belongs to the Nudix hydrolase family
PANGELCK_01189 6.2e-48 XK27_09445 S Domain of unknown function (DUF1827)
PANGELCK_01190 5.8e-172 S oxidoreductase
PANGELCK_01191 4.3e-228 murN 2.3.2.16 V FemAB family
PANGELCK_01192 2.9e-117 M Pfam SNARE associated Golgi protein
PANGELCK_01193 1.9e-107 S Domain of Unknown Function with PDB structure (DUF3862)
PANGELCK_01196 2.5e-204 rpsA 1.17.7.4 J ribosomal protein S1
PANGELCK_01199 3.7e-16 S Protein of unknown function (DUF2969)
PANGELCK_01200 6.3e-201 ilvE 2.6.1.42 E Aminotransferase
PANGELCK_01201 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PANGELCK_01202 4.2e-147 aadK G adenylyltransferase
PANGELCK_01203 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
PANGELCK_01204 3.1e-105 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
PANGELCK_01205 1.4e-12 L Helix-hairpin-helix DNA-binding motif class 1
PANGELCK_01206 2.2e-30 S Domain of unknown function (DUF1912)
PANGELCK_01207 8.5e-168 mmuM 1.5.1.20, 2.1.1.10 H Homocysteine
PANGELCK_01208 1.5e-250 mmuP E amino acid
PANGELCK_01209 3.9e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
PANGELCK_01210 2.6e-225 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PANGELCK_01211 9.7e-22
PANGELCK_01212 8.4e-90 folA 1.5.1.3, 1.5.1.47, 2.1.1.45, 3.5.4.12 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
PANGELCK_01213 1.1e-166 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PANGELCK_01214 7.6e-211 mvaS 2.3.3.10 I synthase
PANGELCK_01215 1e-224 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
PANGELCK_01216 3.3e-77 K hmm pf08876
PANGELCK_01217 2.2e-117 yqfA K protein, Hemolysin III
PANGELCK_01218 4.1e-29 pspC KT PspC domain protein
PANGELCK_01219 6.3e-196 S Protein of unknown function (DUF3114)
PANGELCK_01220 1.3e-152 S hydrolases or acyltransferases (alpha beta hydrolase superfamily)
PANGELCK_01221 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PANGELCK_01222 1.3e-13
PANGELCK_01223 5.9e-244 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
PANGELCK_01224 7.5e-191 dgs 2.4.1.208 GT4 M Glycosyltransferase, group 1 family protein
PANGELCK_01225 0.0 U protein secretion
PANGELCK_01226 6.5e-117 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
PANGELCK_01227 4.7e-20
PANGELCK_01228 5.5e-95 nudF 3.6.1.13 L AdP-ribose pyrophosphatase
PANGELCK_01229 9.6e-245 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PANGELCK_01230 0.0 mgtA 3.6.3.2 P COG0474 Cation transport ATPase
PANGELCK_01231 3.1e-184 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
PANGELCK_01232 8.9e-168 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
PANGELCK_01233 1.5e-169 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
PANGELCK_01234 1.3e-141 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
PANGELCK_01235 6.5e-99 GBS0088 J protein conserved in bacteria
PANGELCK_01236 7.5e-247 merA 1.16.1.1 C Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PANGELCK_01237 6.8e-126 E Alpha beta hydrolase
PANGELCK_01239 1.3e-196 ald 1.4.1.1 C Belongs to the AlaDH PNT family
PANGELCK_01240 8.6e-215 hipO 3.5.1.47 E COG1473 Metal-dependent amidase aminoacylase carboxypeptidase
PANGELCK_01241 2.6e-129 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PANGELCK_01242 8.7e-114 S VIT family
PANGELCK_01243 4.5e-135 deoD_1 2.4.2.3 F Phosphorylase superfamily
PANGELCK_01244 3e-23
PANGELCK_01245 5.2e-27 XK27_00085 K Transcriptional
PANGELCK_01246 2.6e-196 yceA S Belongs to the UPF0176 family
PANGELCK_01247 7.7e-121 sagI S ABC-2 type transporter
PANGELCK_01248 1.3e-165 V ABC transporter
PANGELCK_01249 4e-130 rr02 KT response regulator
PANGELCK_01250 8.8e-208 T signal transduction protein with a C-terminal ATPase domain
PANGELCK_01251 1.7e-120 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
PANGELCK_01252 4.3e-197 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PANGELCK_01253 2.7e-308 lmrA V abc transporter atp-binding protein
PANGELCK_01254 0.0 mdlB V abc transporter atp-binding protein
PANGELCK_01255 2.8e-26 K DNA-binding transcription factor activity
PANGELCK_01256 1.2e-272 opuD M Belongs to the BCCT transporter (TC 2.A.15) family
PANGELCK_01257 2.8e-108 abiGI K Transcriptional regulator, AbiEi antitoxin
PANGELCK_01258 3.2e-102 XK27_00530 M CHAP domain protein
PANGELCK_01260 4.6e-45 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
PANGELCK_01261 5.6e-78 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PANGELCK_01262 6.5e-213 V permease protein
PANGELCK_01263 5.8e-121 macB V ABC transporter, ATP-binding protein
PANGELCK_01264 4e-181 acrA M Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PANGELCK_01265 7.6e-127 2.1.1.223 S Putative SAM-dependent methyltransferase
PANGELCK_01266 0.0 carB 6.3.5.5 F carbamoyl-phosphate synthetase ammonia chain
PANGELCK_01267 2.1e-210 carA 6.3.5.5 F carbamoyl-phosphate synthetase glutamine chain
PANGELCK_01268 1.3e-173 pyrB 2.1.3.2 F Belongs to the ATCase OTCase family
PANGELCK_01269 2.1e-222 pyrP F uracil Permease
PANGELCK_01271 1.8e-87 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PANGELCK_01272 2.5e-161 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PANGELCK_01273 2.8e-76 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PANGELCK_01274 9e-167 fhuR K transcriptional regulator (lysR family)
PANGELCK_01276 1.8e-96
PANGELCK_01277 1.4e-56 S ABC-2 type transporter
PANGELCK_01278 3.7e-157 V AAA domain, putative AbiEii toxin, Type IV TA system
PANGELCK_01282 1.2e-140 ppiA 5.2.1.8 O PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PANGELCK_01283 0.0 pts33BCA 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_01284 3e-07 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PANGELCK_01285 3.1e-251 cycA E permease
PANGELCK_01286 3.5e-39 ynzC S UPF0291 protein
PANGELCK_01287 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
PANGELCK_01288 3.7e-176 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
PANGELCK_01289 1.2e-32 S Glutathione-dependent formaldehyde-activating
PANGELCK_01290 9e-202 S membrane
PANGELCK_01291 1.9e-214 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
PANGELCK_01292 1e-293 nptA P COG1283 Na phosphate symporter
PANGELCK_01293 8e-114 3.4.17.14, 3.5.1.28 NU amidase activity
PANGELCK_01294 3.1e-82 S Bacterial inner membrane protein
PANGELCK_01295 9e-142 XK27_04800 S Sucrose-6F-phosphate phosphohydrolase
PANGELCK_01296 4.6e-104 mur1 3.4.17.14, 3.5.1.28 NU amidase activity
PANGELCK_01297 1.9e-53 glnB K Belongs to the P(II) protein family
PANGELCK_01298 3.1e-226 amt P Ammonium Transporter
PANGELCK_01299 6.2e-157 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PANGELCK_01300 1.2e-54 yabA L Involved in initiation control of chromosome replication
PANGELCK_01301 6.6e-129 yaaT S stage 0 sporulation protein
PANGELCK_01302 6.6e-159 holB 2.7.7.7 L dna polymerase iii
PANGELCK_01303 5.5e-107 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
PANGELCK_01305 0.0 tkt 2.2.1.1 G Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
PANGELCK_01306 5.8e-135 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
PANGELCK_01307 2.8e-224 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PANGELCK_01308 6e-217 ftsW D Belongs to the SEDS family
PANGELCK_01309 2.6e-68 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
PANGELCK_01310 5.1e-262 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PANGELCK_01311 6.2e-157 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PANGELCK_01312 6.5e-279 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PANGELCK_01313 3e-85 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PANGELCK_01314 1.6e-77 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PANGELCK_01315 1.1e-122 atpB C it plays a direct role in the translocation of protons across the membrane
PANGELCK_01316 8.3e-17 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PANGELCK_01317 2.6e-292 S AAA ATPase domain
PANGELCK_01318 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
PANGELCK_01319 0.0 L Superfamily I DNA and RNA helicases and helicase subunits
PANGELCK_01320 4.2e-98 rimL 2.3.1.128, 5.2.1.8 J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PANGELCK_01321 2.6e-103 S COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PANGELCK_01322 8e-15 coiA 3.6.4.12 S Competence protein
PANGELCK_01323 2.2e-15 T peptidase
PANGELCK_01324 2.6e-147 rarD S Transporter
PANGELCK_01325 3.8e-151 thrB 2.7.1.39 E Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
PANGELCK_01326 6.8e-237 hom 1.1.1.3, 2.7.2.4 E homoserine dehydrogenase
PANGELCK_01327 2.7e-128 yxkH G deacetylase
PANGELCK_01328 4.6e-205 argD 2.6.1.11, 2.6.1.17 E acetylornithine aminotransferase
PANGELCK_01329 1.8e-128 argB 2.7.2.8 E Belongs to the acetylglutamate kinase family. ArgB subfamily
PANGELCK_01330 3e-218 argJ 2.3.1.1, 2.3.1.35, 2.7.2.8 E Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
PANGELCK_01331 4.4e-186 argC 1.2.1.38 E Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PANGELCK_01332 5.7e-222 mtnE 2.6.1.83 E mutations do not affect methionine salvage in vivo however
PANGELCK_01333 1.4e-139 cnhA 3.5.1.3 S Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase
PANGELCK_01334 0.0 vanY 3.4.17.14, 3.5.1.28 M D-alanyl-D-alanine carboxypeptidase
PANGELCK_01335 0.0 3.4.17.14, 3.5.1.28 M GBS Bsp-like repeat
PANGELCK_01337 5.9e-09
PANGELCK_01338 1.6e-163 K sequence-specific DNA binding
PANGELCK_01339 3.5e-44 S protein conserved in bacteria
PANGELCK_01340 7.9e-39 S Phage Mu protein F like protein
PANGELCK_01341 1.3e-234 L Transposase
PANGELCK_01345 2e-24 L Terminase small subunit
PANGELCK_01351 3.1e-08
PANGELCK_01353 5e-185 D nuclear chromosome segregation
PANGELCK_01354 1.5e-135 yejC S cyclic nucleotide-binding protein
PANGELCK_01355 2e-163 rapZ S Displays ATPase and GTPase activities
PANGELCK_01356 6.2e-182 ybhK S Required for morphogenesis under gluconeogenic growth conditions
PANGELCK_01357 5.7e-161 whiA K May be required for sporulation
PANGELCK_01358 2.2e-273 pepD E Dipeptidase
PANGELCK_01359 1.1e-142 XK27_10720 D peptidase activity
PANGELCK_01360 5.2e-284 adcA P Belongs to the bacterial solute-binding protein 9 family
PANGELCK_01361 2.6e-09
PANGELCK_01363 3.1e-160 yeiH S Membrane
PANGELCK_01364 2.3e-125 mur1 3.4.17.14, 3.5.1.28 NU muramidase
PANGELCK_01365 2.9e-165 cpsY K Transcriptional regulator
PANGELCK_01366 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
PANGELCK_01367 6.6e-59 phnA P Alkylphosphonate utilization operon protein PhnA
PANGELCK_01368 1.4e-105 artQ P ABC transporter (Permease
PANGELCK_01369 9.8e-112 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_01370 6.7e-156 aatB ET ABC transporter substrate-binding protein
PANGELCK_01371 2.4e-267 uvrX 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PANGELCK_01372 1.1e-49
PANGELCK_01373 2.3e-44
PANGELCK_01374 7.9e-188 adhP 1.1.1.1 C alcohol dehydrogenase
PANGELCK_01375 2.3e-99 rimL J COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins
PANGELCK_01376 1.5e-302 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
PANGELCK_01377 1.7e-125 gntR1 K transcriptional
PANGELCK_01378 2e-55 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
PANGELCK_01379 1.9e-273 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PANGELCK_01380 5.3e-87
PANGELCK_01381 4e-90 niaR S small molecule binding protein (contains 3H domain)
PANGELCK_01382 1.6e-128 K DNA-binding helix-turn-helix protein
PANGELCK_01383 1.6e-157 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
PANGELCK_01384 5e-134 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PANGELCK_01385 1.3e-152 GK ROK family
PANGELCK_01386 8.6e-156 dprA LU DNA protecting protein DprA
PANGELCK_01387 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PANGELCK_01388 1.2e-83 mutF V AAA domain, putative AbiEii toxin, Type IV TA system
PANGELCK_01389 2.2e-51 V ABC-2 family transporter protein
PANGELCK_01391 2.4e-142 S TraX protein
PANGELCK_01392 4.6e-120 KT Transcriptional regulatory protein, C terminal
PANGELCK_01393 5.6e-237 T PhoQ Sensor
PANGELCK_01394 6.9e-256 trmFO 2.1.1.74 J Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
PANGELCK_01395 8e-221 XK27_05470 E Methionine synthase
PANGELCK_01396 1.3e-70 ndk 2.7.4.6 F Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
PANGELCK_01397 3.5e-42 pspE P Rhodanese-like protein
PANGELCK_01398 8.2e-137 IQ Acetoin reductase
PANGELCK_01400 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
PANGELCK_01403 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
PANGELCK_01404 3.1e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
PANGELCK_01405 2.3e-67 mgrA K Transcriptional regulator, MarR family
PANGELCK_01406 4e-145 1.6.5.2 GM NmrA family
PANGELCK_01407 8.6e-128 proV E abc transporter atp-binding protein
PANGELCK_01408 2e-259 proWX P ABC transporter
PANGELCK_01409 3.7e-140 S Phenazine biosynthesis protein
PANGELCK_01410 6.3e-92 2.7.7.65 T Psort location CytoplasmicMembrane, score
PANGELCK_01411 2.8e-132 cbiQ P cobalt transport
PANGELCK_01412 1e-156 P abc transporter atp-binding protein
PANGELCK_01413 3.7e-148 cbiO2 P ABC transporter, ATP-binding protein
PANGELCK_01414 9.8e-64 pnuC H nicotinamide mononucleotide transporter
PANGELCK_01415 1.6e-65 K Transcriptional regulator
PANGELCK_01416 3.6e-177 1.1.1.1 C nadph quinone reductase
PANGELCK_01417 1e-153 I Alpha/beta hydrolase family
PANGELCK_01418 1.1e-148 IQ Belongs to the short-chain dehydrogenases reductases (SDR) family
PANGELCK_01419 8.4e-38
PANGELCK_01420 2.1e-58 S Protein of unknown function with HXXEE motif
PANGELCK_01421 1.3e-93 K Transcriptional regulator, TetR family
PANGELCK_01422 6.8e-151 czcD P cation diffusion facilitator family transporter
PANGELCK_01423 6.7e-193 hemH 4.99.1.1, 4.99.1.9 H Catalyzes the ferrous insertion into protoporphyrin IX
PANGELCK_01424 9.5e-189 adhB 1.1.1.1, 1.1.1.14 E Dehydrogenase
PANGELCK_01425 1.6e-64 copY K Copper transport repressor, CopY TcrY family
PANGELCK_01426 1.5e-64 silP 1.9.3.1, 3.6.3.54 S cog cog4633
PANGELCK_01427 0.0 copA 3.6.3.54 P P-type ATPase
PANGELCK_01428 1.1e-85 spxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
PANGELCK_01429 8.3e-138 G protein with an alpha beta hydrolase fold
PANGELCK_01432 1.6e-126 ybhF_2 V abc transporter atp-binding protein
PANGELCK_01433 2.8e-175 ybhR V ABC transporter
PANGELCK_01434 4.5e-109 K Bacterial regulatory proteins, tetR family
PANGELCK_01435 3.5e-140 2.4.2.3 F Phosphorylase superfamily
PANGELCK_01436 6e-109 gph 3.1.3.18 S HAD hydrolase, family IA, variant 1
PANGELCK_01437 0.0 V Type III restriction enzyme, res subunit
PANGELCK_01438 1.1e-173 yclQ P ABC-type enterochelin transport system, periplasmic component
PANGELCK_01439 3.1e-232 dinF V Mate efflux family protein
PANGELCK_01440 4e-276 S Psort location CytoplasmicMembrane, score
PANGELCK_01441 6.2e-307 FbpA K RNA-binding protein homologous to eukaryotic snRNP
PANGELCK_01442 1.2e-133 S TraX protein
PANGELCK_01443 6.1e-94 thiJ 2.7.11.1, 3.5.1.124 S DJ-1 family
PANGELCK_01444 2.9e-145 pyrK C Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )
PANGELCK_01445 4.5e-177 pyrD 1.3.1.14, 1.3.98.1 F Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily
PANGELCK_01446 5e-125 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
PANGELCK_01447 1.7e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PANGELCK_01448 1.8e-230 nylA 3.5.1.4 J Belongs to the amidase family
PANGELCK_01449 4.6e-149 yckB ET Belongs to the bacterial solute-binding protein 3 family
PANGELCK_01450 9.3e-81 yecS P ABC transporter (Permease
PANGELCK_01451 0.0 sasH 3.1.3.5, 3.6.1.45 F Belongs to the 5'-nucleotidase family
PANGELCK_01452 7.1e-170 bglC K Transcriptional regulator
PANGELCK_01453 2.8e-244 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PANGELCK_01454 1.3e-238 agcS E (Alanine) symporter
PANGELCK_01455 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
PANGELCK_01456 1.5e-239 metY 2.5.1.49 E o-acetylhomoserine
PANGELCK_01457 8.9e-107 S haloacid dehalogenase-like hydrolase
PANGELCK_01458 4.2e-86 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
PANGELCK_01459 6.2e-111 hsdS2 2.1.1.72 V Type I restriction modification DNA specificity domain
PANGELCK_01460 1e-34 M1-755 P Hemerythrin HHE cation binding domain protein
PANGELCK_01461 5e-238 XK27_04775 S hemerythrin HHE cation binding domain
PANGELCK_01462 2.9e-143 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PANGELCK_01463 4.3e-169 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
PANGELCK_01464 7.2e-71 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
PANGELCK_01465 1e-44 yktA S Belongs to the UPF0223 family
PANGELCK_01466 5.9e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
PANGELCK_01467 2.4e-245 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
PANGELCK_01468 2.6e-155 pstS P phosphate
PANGELCK_01469 1.4e-156 pstC P probably responsible for the translocation of the substrate across the membrane
PANGELCK_01470 9.1e-156 pstA P phosphate transport system permease
PANGELCK_01471 4e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PANGELCK_01472 3.5e-140 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
PANGELCK_01473 3.2e-113 phoU P Plays a role in the regulation of phosphate uptake
PANGELCK_01474 0.0 pepN 3.4.11.2 E aminopeptidase
PANGELCK_01475 1.1e-192 xerS D Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division
PANGELCK_01476 1e-184 lplA 6.3.1.20 H Lipoate-protein ligase
PANGELCK_01477 1.5e-38
PANGELCK_01478 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PANGELCK_01479 1.2e-298 malQ 2.4.1.25 GH77 G 4-alpha-glucanotransferase
PANGELCK_01480 7.8e-172 malR K Transcriptional regulator
PANGELCK_01481 3.6e-227 malX G ABC transporter
PANGELCK_01482 2.6e-250 malF P ABC transporter (Permease
PANGELCK_01483 2.2e-151 malG P ABC transporter (Permease
PANGELCK_01484 8.8e-212 msmX P Belongs to the ABC transporter superfamily
PANGELCK_01485 1.9e-23 tatA U protein secretion
PANGELCK_01486 6.4e-123 tatC U Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PANGELCK_01487 1.7e-291 ywbL P COG0672 High-affinity Fe2 Pb2 permease
PANGELCK_01488 6.4e-229 ycdB P peroxidase
PANGELCK_01489 5.1e-143 ycdO P periplasmic lipoprotein involved in iron transport
PANGELCK_01490 0.0 pulA 3.2.1.1, 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PANGELCK_01491 0.0 3.5.1.28 M N-Acetylmuramoyl-L-alanine amidase
PANGELCK_01492 0.0 3.5.1.28 NU amidase activity
PANGELCK_01493 0.0 lpdA 1.8.1.4 C Dehydrogenase
PANGELCK_01494 3.5e-207 acoC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
PANGELCK_01495 6.4e-182 acoB 1.2.4.1, 1.2.4.4 C COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit
PANGELCK_01496 5.6e-183 acoA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
PANGELCK_01497 2.4e-202 hpk9 2.7.13.3 T protein histidine kinase activity
PANGELCK_01498 3.5e-225 2.7.13.3 T protein histidine kinase activity
PANGELCK_01499 0.0 S the current gene model (or a revised gene model) may contain a frame shift
PANGELCK_01500 9.1e-234 pyrC 3.5.2.3 F Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily
PANGELCK_01501 3.8e-119 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PANGELCK_01502 4.7e-216 yeaB K Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PANGELCK_01503 4.8e-249 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PANGELCK_01504 2.7e-183 dacA1 3.4.16.4 M Belongs to the peptidase S11 family
PANGELCK_01505 8.7e-156 rssA S Phospholipase, patatin family
PANGELCK_01506 6.5e-100 estA E Lysophospholipase L1 and related esterases
PANGELCK_01507 1.4e-284 S unusual protein kinase
PANGELCK_01508 4.9e-39 S granule-associated protein
PANGELCK_01509 6.8e-286 bglH 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
PANGELCK_01510 2.6e-195 S hmm pf01594
PANGELCK_01511 9.9e-106 G Belongs to the phosphoglycerate mutase family
PANGELCK_01512 5.4e-107 G Belongs to the phosphoglycerate mutase family
PANGELCK_01513 1e-105 pgm G Belongs to the phosphoglycerate mutase family
PANGELCK_01514 2.5e-136 supH 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
PANGELCK_01516 1.3e-177 wbbI M transferase activity, transferring glycosyl groups
PANGELCK_01517 4e-184 sacB GT2,GT4 M Stealth protein CR2, conserved region 2
PANGELCK_01518 4.1e-214 glf 5.4.99.9 M UDP-galactopyranose mutase
PANGELCK_01519 8.3e-244 epsU S Polysaccharide biosynthesis protein
PANGELCK_01520 1.5e-126 cps3F
PANGELCK_01521 2.7e-194 M Glycosyltransferase like family 2
PANGELCK_01522 1.7e-163
PANGELCK_01523 4e-121 Z012_10770 M Domain of unknown function (DUF1919)
PANGELCK_01524 1.8e-212 wcoF M Glycosyltransferase, group 1 family protein
PANGELCK_01525 7.4e-214 rgpAc GT4 M group 1 family protein
PANGELCK_01526 6.8e-251 cpsE M Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase
PANGELCK_01527 1e-115 cpsD D COG0489 ATPases involved in chromosome partitioning
PANGELCK_01528 2e-110 cps4C M biosynthesis protein
PANGELCK_01529 8.9e-133 cpsB 3.1.3.48 GM Capsular polysaccharide biosynthesis protein
PANGELCK_01530 4.7e-250 cps4A K Cell envelope-like function transcriptional attenuator common domain protein
PANGELCK_01531 4.9e-128 deoD 2.4.2.1, 2.4.2.28 F purine nucleoside phosphorylase
PANGELCK_01532 6.7e-133 yfeJ 6.3.5.2 F glutamine amidotransferase
PANGELCK_01533 3.5e-161 clcA_2 P chloride
PANGELCK_01534 6.4e-51 S LemA family
PANGELCK_01535 1.7e-148 punA 2.4.2.1 F The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PANGELCK_01536 1.1e-95 S Protein of unknown function (DUF1697)
PANGELCK_01537 1.3e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
PANGELCK_01538 1.5e-121 rpiA 2.7.1.12, 2.7.1.15, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
PANGELCK_01539 7.4e-253 V Glucan-binding protein C
PANGELCK_01540 1.8e-31 M tape measure protein
PANGELCK_01544 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PANGELCK_01545 2.6e-97 hpt 2.4.2.8, 6.3.4.19 F Belongs to the purine pyrimidine phosphoribosyltransferase family
PANGELCK_01546 4.4e-228 tilS 2.4.2.8, 6.3.4.19 D Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
PANGELCK_01547 2.5e-231 XK27_09285 3.5.2.6 V Beta-lactamase enzyme family
PANGELCK_01549 8.7e-60 divIC D Septum formation initiator
PANGELCK_01550 2.2e-39 yabO J Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
PANGELCK_01551 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PANGELCK_01552 8.9e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
PANGELCK_01553 3.3e-203 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
PANGELCK_01554 3.2e-29 yyzM S Protein conserved in bacteria
PANGELCK_01555 4.2e-198 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
PANGELCK_01556 2.2e-254 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PANGELCK_01557 3.2e-133 parB K Belongs to the ParB family
PANGELCK_01558 1.5e-201 htrA 3.4.21.107 O Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain'
PANGELCK_01559 6.8e-81 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PANGELCK_01560 2.2e-117 yoaK S Protein of unknown function (DUF1275)
PANGELCK_01564 0.0 XK27_10405 S Bacterial membrane protein YfhO
PANGELCK_01565 1.1e-305 ybiT S abc transporter atp-binding protein
PANGELCK_01566 9.3e-153 yvjA S membrane
PANGELCK_01567 7.2e-189 trpS 6.1.1.2 J Tryptophanyl-tRNA synthetase
PANGELCK_01568 1.1e-273 guaB 1.1.1.205 F Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
PANGELCK_01569 3.7e-199 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PANGELCK_01570 1.9e-57 yaaA S S4 domain protein YaaA
PANGELCK_01571 2.5e-228 ymfF S Peptidase M16
PANGELCK_01572 9.2e-234 ymfH S Peptidase M16
PANGELCK_01573 1e-127 S sequence-specific DNA binding
PANGELCK_01574 2.6e-89 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
PANGELCK_01575 3.5e-149 ecfA1 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PANGELCK_01576 1.2e-149 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PANGELCK_01577 2.2e-132 ecfT P Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
PANGELCK_01578 5.9e-71 lytE M LysM domain protein
PANGELCK_01579 3.5e-62 isaA GH23 M Immunodominant staphylococcal antigen A
PANGELCK_01580 2.1e-305 S Bacterial membrane protein, YfhO
PANGELCK_01581 4.3e-219 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
PANGELCK_01582 8.7e-97 yvbG U UPF0056 membrane protein
PANGELCK_01583 0.0 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
PANGELCK_01584 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
PANGELCK_01585 2.2e-73 rplI J binds to the 23S rRNA
PANGELCK_01586 1.9e-245 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
PANGELCK_01587 1.8e-47 veg S Biofilm formation stimulator VEG
PANGELCK_01588 5.8e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PANGELCK_01589 1.1e-10
PANGELCK_01590 6.5e-52 ypaA M Membrane
PANGELCK_01591 7.9e-94 XK27_06935 K transcriptional regulator
PANGELCK_01592 1.1e-160 XK27_06930 V domain protein
PANGELCK_01593 7.2e-102 S Putative adhesin
PANGELCK_01594 6.2e-60 XK27_06920 S Protein of unknown function (DUF1700)
PANGELCK_01595 3.5e-52 K transcriptional regulator, PadR family
PANGELCK_01596 4.1e-115 nudL L hydrolase
PANGELCK_01600 6.7e-19 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PANGELCK_01601 3.4e-25 rpmF J Belongs to the bacterial ribosomal protein bL32 family
PANGELCK_01602 4.7e-218 metE 2.1.1.14 E Methionine synthase
PANGELCK_01603 1.4e-07 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_01604 1.2e-27 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_01605 5.8e-37 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_01606 2e-30 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_01607 2.1e-238 hisS 6.1.1.21 J histidyl-tRNA synthetase
PANGELCK_01609 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
PANGELCK_01610 1.4e-167 XK27_01785 S cog cog1284
PANGELCK_01611 5.4e-119 yaaA S Belongs to the UPF0246 family
PANGELCK_01612 5.9e-114 nrdG 1.97.1.4 O Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
PANGELCK_01613 2.8e-85 XK27_10930 K acetyltransferase
PANGELCK_01614 7.5e-14
PANGELCK_01615 0.0 nrdD 1.1.98.6 F Ribonucleoside-triphosphate reductase
PANGELCK_01616 1.1e-287 ccs S the current gene model (or a revised gene model) may contain a frame shift
PANGELCK_01617 3.2e-44 yrzB S Belongs to the UPF0473 family
PANGELCK_01618 1.8e-69 yqgF L Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PANGELCK_01619 3.1e-43 yrzL S Belongs to the UPF0297 family
PANGELCK_01620 8.4e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
PANGELCK_01621 6.3e-235 rarA L ATPase related to the helicase subunit of the Holliday junction resolvase
PANGELCK_01623 1.3e-215 int L Belongs to the 'phage' integrase family
PANGELCK_01624 1.4e-18 S Domain of unknown function (DUF3173)
PANGELCK_01625 6.3e-158 L Replication initiation factor
PANGELCK_01626 2.1e-88 K sequence-specific DNA binding
PANGELCK_01627 5.2e-79 S Short repeat of unknown function (DUF308)
PANGELCK_01628 1.8e-78 S membrane protein of uknown function UCP014873
PANGELCK_01629 1.7e-95 bcrC 3.6.1.27 I Acid phosphatase homologues
PANGELCK_01630 1.9e-89 adk 2.7.4.3 F topology modulation protein
PANGELCK_01631 4.1e-250 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PANGELCK_01632 2.6e-79 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PANGELCK_01633 2.8e-35 XK27_09805 S MORN repeat protein
PANGELCK_01634 0.0 XK27_09800 I Acyltransferase
PANGELCK_01635 1e-187 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
PANGELCK_01636 2.9e-48 rpsJ J Involved in the binding of tRNA to the ribosomes
PANGELCK_01637 2.4e-110 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PANGELCK_01638 5.7e-104 rplD J Forms part of the polypeptide exit tunnel
PANGELCK_01639 2.4e-44 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
PANGELCK_01640 6.8e-153 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PANGELCK_01641 8.3e-47 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PANGELCK_01642 7.3e-53 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PANGELCK_01643 1.6e-117 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PANGELCK_01644 1.1e-71 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PANGELCK_01645 3.5e-26 rpmC J Belongs to the universal ribosomal protein uL29 family
PANGELCK_01646 6e-39 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PANGELCK_01647 3.9e-60 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PANGELCK_01648 1.4e-47 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PANGELCK_01649 1.6e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PANGELCK_01650 1.5e-28 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PANGELCK_01651 1.2e-67 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PANGELCK_01652 6.6e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PANGELCK_01653 1.9e-56 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PANGELCK_01654 1.3e-79 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PANGELCK_01655 1.9e-23 rpmD J ribosomal protein l30
PANGELCK_01656 5.7e-58 rplO J binds to the 23S rRNA
PANGELCK_01657 2.1e-230 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
PANGELCK_01658 5.6e-115 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
PANGELCK_01659 2.7e-32 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PANGELCK_01660 6e-15 rpmJ J Belongs to the bacterial ribosomal protein bL36 family
PANGELCK_01661 4e-57 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PANGELCK_01662 1.9e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PANGELCK_01663 3.6e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PANGELCK_01664 4.4e-62 rplQ J ribosomal protein l17
PANGELCK_01665 6.2e-246 6.3.2.2 H gamma-glutamylcysteine synthetase
PANGELCK_01667 1.3e-165 fba 4.1.2.13, 4.1.2.29 G aldolase
PANGELCK_01670 5.1e-96 ywlG S Belongs to the UPF0340 family
PANGELCK_01671 4.7e-257 treC 3.2.1.93 GH13 G COG0366 Glycosidases
PANGELCK_01672 0.0 pepO 3.4.24.71 O Peptidase family M13
PANGELCK_01673 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
PANGELCK_01676 1.6e-274 thrC 4.2.3.1 E Threonine synthase
PANGELCK_01677 8.7e-224 norN V Mate efflux family protein
PANGELCK_01678 1.4e-57 asp S cog cog1302
PANGELCK_01679 4.2e-303 yloV S kinase related to dihydroxyacetone kinase
PANGELCK_01680 0.0 ilvD 4.2.1.9 E Belongs to the IlvD Edd family
PANGELCK_01681 0.0 ilvB 2.2.1.6 EH Acetolactate synthase
PANGELCK_01682 5e-76 ilvN 2.2.1.6 E Acetolactate synthase
PANGELCK_01683 1.3e-193 ilvC 1.1.1.86 H Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PANGELCK_01684 5.5e-239 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PANGELCK_01685 0.0 pbp1B 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PANGELCK_01686 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PANGELCK_01687 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PANGELCK_01688 5e-68 S cog cog4699
PANGELCK_01689 2.4e-175 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PANGELCK_01690 5.1e-148 comGA NU Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
PANGELCK_01691 2.2e-43 comGC U Required for transformation and DNA binding
PANGELCK_01692 8.4e-70 cglD NU Competence protein
PANGELCK_01693 1.1e-15 NU Type II secretory pathway pseudopilin
PANGELCK_01694 3.8e-70 comGF U Competence protein ComGF
PANGELCK_01695 2.4e-13 comGF U Putative Competence protein ComGF
PANGELCK_01696 5.5e-175 ytxK 2.1.1.72 L DNA methylase
PANGELCK_01697 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PANGELCK_01698 1.5e-26 lanR K sequence-specific DNA binding
PANGELCK_01699 3.2e-105 V CAAX protease self-immunity
PANGELCK_01701 4e-100 S CAAX amino terminal protease family protein
PANGELCK_01702 1.1e-130 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PANGELCK_01703 9.1e-203 pepA 3.4.11.7 G COG1363 Cellulase M and related proteins
PANGELCK_01704 2.7e-08 XK27_10305 S Domain of unknown function (DUF4651)
PANGELCK_01705 7.9e-54 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
PANGELCK_01706 2e-09 S NTF2 fold immunity protein
PANGELCK_01707 1.9e-112 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
PANGELCK_01708 6.1e-188 yeeE S Sulphur transport
PANGELCK_01709 8.3e-37 yeeD O sulfur carrier activity
PANGELCK_01710 6.6e-66 ssb_2 L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
PANGELCK_01711 5.1e-90 tadA 3.5.4.1, 3.5.4.33 FJ Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
PANGELCK_01715 3.5e-157 rrmA 2.1.1.187 Q methyltransferase
PANGELCK_01716 1.4e-128 S HAD hydrolase, family IA, variant
PANGELCK_01717 5.3e-58 dapD 2.3.1.117, 2.3.1.89 E Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate
PANGELCK_01718 7.4e-219 hipO 3.5.1.47 E Catalyzes the conversion of N-acetyl-diaminopimelate to diaminopimelate and acetate
PANGELCK_01719 3.5e-94 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PANGELCK_01720 9.1e-116 gluP 3.4.21.105 O membrane protein (homolog of Drosophila rhomboid)
PANGELCK_01721 5.7e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
PANGELCK_01722 5.3e-184 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
PANGELCK_01723 1.9e-95 XK27_08585 S Psort location CytoplasmicMembrane, score
PANGELCK_01724 1.6e-140 fnt P Formate nitrite transporter
PANGELCK_01725 7.9e-230 XK27_09615 C reductase
PANGELCK_01726 6.3e-108 XK27_09620 S FMN reductase (NADPH) activity
PANGELCK_01727 2.1e-76 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
PANGELCK_01728 4.2e-75 3.5.1.19 Q hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
PANGELCK_01729 1.2e-225 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PANGELCK_01730 1.6e-126 WQ51_05710 S Mitochondrial biogenesis AIM24
PANGELCK_01731 3.3e-86 cah 4.2.1.1 P Reversible hydration of carbon dioxide
PANGELCK_01732 1.2e-50 S Protein of unknown function (DUF3397)
PANGELCK_01733 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PANGELCK_01734 2.6e-118 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
PANGELCK_01735 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PANGELCK_01736 5.1e-273 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PANGELCK_01737 1.7e-230 2.7.13.3 T signal transduction protein with a C-terminal ATPase domain
PANGELCK_01738 1.5e-150 hpk9 2.7.13.3 T protein histidine kinase activity
PANGELCK_01739 2.5e-207 hpk9 2.7.13.3 T protein histidine kinase activity
PANGELCK_01740 1.2e-225 fasC 2.7.13.3 T protein histidine kinase activity
PANGELCK_01741 2.7e-129 fasA KT Response regulator of the LytR AlgR family
PANGELCK_01742 1.1e-228 argG 6.3.4.5 E Belongs to the argininosuccinate synthase family. Type 1 subfamily
PANGELCK_01743 7.8e-263 argH 4.3.2.1 E Argininosuccinate lyase
PANGELCK_01744 3.8e-54 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
PANGELCK_01745 1.7e-140 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PANGELCK_01746 3.2e-168 jag S RNA-binding protein
PANGELCK_01747 9.9e-98 K Transcriptional regulator
PANGELCK_01748 2.7e-97 1.6.5.2 S NADPH-quinone reductase (modulator of drug activity B)
PANGELCK_01749 3.4e-14 rpmH J Ribosomal protein L34
PANGELCK_01750 7e-225 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
PANGELCK_01751 1.2e-46 sptS 2.7.13.3 T Histidine kinase
PANGELCK_01753 7.7e-96 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
PANGELCK_01754 7.3e-15 M domain protein
PANGELCK_01756 1.1e-09
PANGELCK_01757 3.4e-195 XK27_10075 S abc transporter atp-binding protein
PANGELCK_01760 0.0 V abc transporter atp-binding protein
PANGELCK_01761 3.8e-299 V abc transporter atp-binding protein
PANGELCK_01762 0.0 gshF 6.3.2.2, 6.3.2.29, 6.3.2.30, 6.3.2.4 H Belongs to the glutamate--cysteine ligase type 1 family
PANGELCK_01764 3.5e-272 S Protein of unknown function (DUF3114)
PANGELCK_01765 1.3e-99 2.3.1.128 K Acetyltransferase GNAT Family
PANGELCK_01766 0.0 glgP 2.4.1.1 GT35 G Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties
PANGELCK_01767 9.2e-283 glgA 2.4.1.21 GT5 G Synthesizes alpha-1,4-glucan chains using ADP-glucose
PANGELCK_01768 4.4e-179 glgD 2.4.1.21, 2.7.7.27 GT5 G glucose-1-phosphate adenylyltransferase
PANGELCK_01769 1e-188 glgC 2.7.7.27 H Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
PANGELCK_01770 0.0 glgB 2.4.1.18, 3.2.1.141, 3.2.1.20 CBM48,GH13,GH31 G Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PANGELCK_01771 0.0 pulA 3.2.1.41 CBM48,GH13 G belongs to the glycosyl hydrolase 13 family
PANGELCK_01772 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
PANGELCK_01773 3.9e-187 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
PANGELCK_01774 1.9e-135 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
PANGELCK_01775 2.2e-93 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PANGELCK_01778 3.1e-113 vraR K Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain
PANGELCK_01779 1.9e-170 vraS 2.7.13.3 T Histidine kinase
PANGELCK_01780 1.2e-115 yvqF S Membrane
PANGELCK_01781 1e-94 kcsA P Ion transport protein
PANGELCK_01782 7.5e-293 prkC 2.7.11.1 KLT serine threonine protein kinase
PANGELCK_01783 1e-134 stp 3.1.3.16 T phosphatase
PANGELCK_01784 2.8e-241 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PANGELCK_01785 1.7e-168 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PANGELCK_01786 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PANGELCK_01787 2.3e-45 rpoZ 2.7.7.6 K DNA-directed 5'-3' RNA polymerase activity
PANGELCK_01788 4.4e-112 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
PANGELCK_01789 6.6e-193 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
PANGELCK_01790 3.1e-142 XK27_02985 S overlaps another CDS with the same product name
PANGELCK_01791 1e-145 supH S overlaps another CDS with the same product name
PANGELCK_01792 1.2e-59 yvoA_1 K Transcriptional
PANGELCK_01793 5.4e-119 skfE V abc transporter atp-binding protein
PANGELCK_01794 4.9e-129 V Psort location CytoplasmicMembrane, score
PANGELCK_01795 1e-170 oppF P Belongs to the ABC transporter superfamily
PANGELCK_01796 3.5e-202 oppD P Belongs to the ABC transporter superfamily
PANGELCK_01797 5.9e-166 amiD P ABC transporter (Permease
PANGELCK_01798 6.6e-276 amiC P ABC transporter (Permease
PANGELCK_01799 2.5e-310 amiA E ABC transporter, substrate-binding protein, family 5
PANGELCK_01800 0.0 amiA E ABC transporter, substrate-binding protein, family 5
PANGELCK_01801 5.7e-175 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
PANGELCK_01802 9.2e-172 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
PANGELCK_01803 7.5e-152 nadK 2.7.1.23 H Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PANGELCK_01804 3.9e-119 yjbM 2.7.6.5 S Gtp pyrophosphokinase
PANGELCK_01805 2.4e-101 yjbK S Adenylate cyclase
PANGELCK_01806 1.9e-175 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PANGELCK_01807 3.9e-204 iscS 2.8.1.7 E Cysteine desulfurase
PANGELCK_01808 1.8e-59 XK27_04120 S Putative amino acid metabolism
PANGELCK_01809 1.5e-118 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
PANGELCK_01810 2.2e-128 puuD T peptidase C26
PANGELCK_01811 1.2e-118 radC E Belongs to the UPF0758 family
PANGELCK_01812 0.0 rgpF M Rhamnan synthesis protein F
PANGELCK_01813 6.2e-188 rgpEc GT2 M Glycosyl transferase family 2
PANGELCK_01814 1.8e-223 rgpD 3.6.3.38 P Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
PANGELCK_01815 2e-141 rgpC GM Transport permease protein
PANGELCK_01816 1e-173 rgpB GT2 M Glycosyltransferase, group 2 family protein
PANGELCK_01817 1.2e-219 rgpA GT4 M Domain of unknown function (DUF1972)
PANGELCK_01818 1.4e-140 S Predicted membrane protein (DUF2142)
PANGELCK_01819 2.8e-129 2.7.8.12 M transferase activity, transferring glycosyl groups
PANGELCK_01820 2.8e-214 amrA S polysaccharide biosynthetic process
PANGELCK_01821 2.6e-47 XK27_09090 S Uncharacterized conserved protein (DUF2304)
PANGELCK_01822 1.9e-124 ycbB S Glycosyl transferase family 2
PANGELCK_01823 6.5e-159 rfbD 1.1.1.133, 5.1.3.13 M Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose
PANGELCK_01824 2.6e-169 yfdH GT2 M COG0463, glycosyltransferases involved in cell wall biogenesis
PANGELCK_01825 5.9e-55 yitW K metal-sulfur cluster biosynthetic enzyme
PANGELCK_01826 8.9e-201 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
PANGELCK_01827 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
PANGELCK_01828 4.2e-49 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
PANGELCK_01829 3.2e-20 rpsU J Belongs to the bacterial ribosomal protein bS21 family
PANGELCK_01830 6.1e-135 gltS ET Belongs to the bacterial solute-binding protein 3 family
PANGELCK_01831 2.8e-210 arcT 2.6.1.1 E Aminotransferase
PANGELCK_01832 1.7e-137 ET Belongs to the bacterial solute-binding protein 3 family
PANGELCK_01833 6.4e-140 ET ABC transporter
PANGELCK_01834 1.2e-82 mutT 3.6.1.55 F Nudix family
PANGELCK_01835 1.8e-10 S the current gene model (or a revised gene model) may contain a frame shift
PANGELCK_01836 2.1e-27
PANGELCK_01837 1e-113 ycaK 1.6.5.2 S NADPH-dependent FMN reductase
PANGELCK_01838 1.2e-83 MA20_25245 K Gnat family
PANGELCK_01839 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
PANGELCK_01841 4.9e-160 S CAAX amino terminal protease family protein
PANGELCK_01842 0.0 glnP P ABC-type amino acid transport signal transduction systems periplasmic component domain
PANGELCK_01843 1.6e-134 glnQ 3.6.3.21 E abc transporter atp-binding protein
PANGELCK_01844 1.7e-17 XK27_00735
PANGELCK_01845 8.8e-248 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PANGELCK_01847 2.3e-128 rsuA 5.4.99.19, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PANGELCK_01848 9.8e-10 O ADP-ribosylglycohydrolase
PANGELCK_01849 9.6e-62 paaI Q protein possibly involved in aromatic compounds catabolism
PANGELCK_01850 7.8e-61 ycaO O OsmC-like protein
PANGELCK_01852 5.7e-150 EG Permeases of the drug metabolite transporter (DMT) superfamily
PANGELCK_01853 8.5e-08 N PFAM Uncharacterised protein family UPF0150
PANGELCK_01854 6.5e-111 serB 3.1.3.3 E phosphoserine phosphatase
PANGELCK_01855 1.9e-298 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
PANGELCK_01856 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PANGELCK_01857 5.5e-98 3.1.3.18 S IA, variant 1
PANGELCK_01858 1.6e-115 lrgB M Inhibits the expression or activity of extracellular murein hydrolases by interacting, possibly with LrgA, with the holin-like proteins CidA and or CidB. The LrgAB and CidAB proteins may affect the proton motive force of the membrane. May be involved in programmed cell death (PCD), possibly triggering PCD in response to antibiotics and environmental stresses
PANGELCK_01859 1e-55 lrgA S Effector of murein hydrolase LrgA
PANGELCK_01861 5.4e-59 arsC 1.20.4.1 P Belongs to the ArsC family
PANGELCK_01862 9.2e-73 ogt 2.1.1.63, 3.2.2.20 L methylated-DNA-[protein]-cysteine S-methyltransferase activity
PANGELCK_01863 4.5e-219 serA 1.1.1.399, 1.1.1.95 EH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PANGELCK_01864 2.4e-101 wecD M Acetyltransferase (GNAT) domain
PANGELCK_01865 5.1e-209 serC 2.6.1.52 E Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PANGELCK_01866 8.9e-151 GK ROK family
PANGELCK_01867 6.9e-71 gloA 4.4.1.5 E Lactoylglutathione lyase
PANGELCK_01868 1.9e-145 XK27_08050 O HflC and HflK could regulate a protease
PANGELCK_01869 4.4e-205 potD P spermidine putrescine ABC transporter
PANGELCK_01870 2.3e-131 potC P ABC-type spermidine putrescine transport system, permease component II
PANGELCK_01871 4.1e-139 potB P ABC-type spermidine putrescine transport system, permease component I
PANGELCK_01872 5.2e-212 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
PANGELCK_01873 3.1e-167 murB 1.3.1.98 M cell wall formation
PANGELCK_01874 8.2e-82 folK 2.7.6.3, 4.1.2.25 H 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
PANGELCK_01875 3.8e-60 folB 1.13.11.81, 2.5.1.15, 2.7.6.3, 4.1.2.25, 5.1.99.8 H Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PANGELCK_01876 7.1e-291 amy 3.2.1.1 GH13 G Belongs to the glycosyl hydrolase 13 family
PANGELCK_01877 2.9e-145 folP 2.5.1.15, 2.7.6.3 H Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PANGELCK_01878 7.7e-100 folE 3.5.4.16 F gtp cyclohydrolase
PANGELCK_01879 0.0 ydaO E amino acid
PANGELCK_01880 2.2e-235 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
PANGELCK_01881 1.5e-36 ylqC L Belongs to the UPF0109 family
PANGELCK_01882 2.4e-43 rpsP J Belongs to the bacterial ribosomal protein bS16 family
PANGELCK_01884 1e-211 2.7.13.3 T protein histidine kinase activity
PANGELCK_01885 4.2e-122 agrA KT phosphorelay signal transduction system
PANGELCK_01886 1.5e-162 O protein import
PANGELCK_01887 4.3e-166 tehB 2.1.1.265 PQ tellurite resistance protein tehb
PANGELCK_01888 3.7e-17 yjdB S Domain of unknown function (DUF4767)
PANGELCK_01890 3.4e-157 xth 3.1.11.2 L exodeoxyribonuclease III
PANGELCK_01891 5.8e-72 S QueT transporter
PANGELCK_01893 8e-169 yfjR K regulation of single-species biofilm formation
PANGELCK_01895 3.1e-184 yegS 2.7.1.107 I Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase
PANGELCK_01896 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PANGELCK_01897 4.8e-85 ccl S cog cog4708
PANGELCK_01898 6.5e-160 rbn E Belongs to the UPF0761 family
PANGELCK_01899 1.1e-166 map 3.4.11.18 E Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed
PANGELCK_01900 7.3e-231 ytoI K transcriptional regulator containing CBS domains
PANGELCK_01901 2.8e-99 XK27_07830 2.3.1.128 J Acetyltransferase GNAT Family
PANGELCK_01902 2.1e-230 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PANGELCK_01903 0.0 comEC S Competence protein ComEC
PANGELCK_01904 8.6e-93 comEA L COG1555 DNA uptake protein and related DNA-binding proteins
PANGELCK_01905 1.1e-141 plsC 2.3.1.51 I Acyltransferase
PANGELCK_01906 8.1e-147 nodB3 G Polysaccharide deacetylase
PANGELCK_01907 4.6e-140 yabB 2.1.1.223 L Methyltransferase
PANGELCK_01908 1e-41 yazA L endonuclease containing a URI domain
PANGELCK_01909 2.4e-49 L COG1943 Transposase and inactivated derivatives
PANGELCK_01910 1.9e-88 L COG1943 Transposase and inactivated derivatives
PANGELCK_01912 4.7e-94 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PANGELCK_01913 2.6e-83 comFC K competence protein
PANGELCK_01914 1.9e-250 comFA L Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
PANGELCK_01915 4.5e-109 yvyE 3.4.13.9 S YigZ family
PANGELCK_01916 6.3e-168 cysK 2.5.1.47 E Belongs to the cysteine synthase cystathionine beta- synthase family
PANGELCK_01917 3.5e-112 acuB S CBS domain
PANGELCK_01918 1.6e-123 livF E COG0410 ABC-type branched-chain amino acid transport systems, ATPase component
PANGELCK_01919 1.1e-136 livG E COG0411 ABC-type branched-chain amino acid transport systems, ATPase component
PANGELCK_01920 4.9e-139 livM E Belongs to the binding-protein-dependent transport system permease family
PANGELCK_01921 1.2e-144 livH E Belongs to the binding-protein-dependent transport system permease family
PANGELCK_01922 1e-210 livJ E COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component
PANGELCK_01923 5.4e-46 ylbG S UPF0298 protein
PANGELCK_01924 2.7e-71 ylbF S Belongs to the UPF0342 family
PANGELCK_01925 3.7e-105 clpP 3.4.21.92 OU Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
PANGELCK_01926 5.7e-112 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PANGELCK_01927 0.0 sacB 2.4.1.10, 2.4.1.9, 3.2.1.26 GH32,GH68 G Belongs to the glycosyl hydrolase 68 family
PANGELCK_01928 6.6e-304 3.2.1.26, 3.2.1.65 GH32 G Belongs to the glycosyl hydrolase 32 family
PANGELCK_01929 1.3e-221 malY 4.4.1.8 E COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities
PANGELCK_01930 3e-201 metB 2.5.1.48, 4.4.1.8 E cystathionine
PANGELCK_01931 0.0 pacL 3.6.3.8, 3.6.3.9 P cation transport ATPase
PANGELCK_01932 3.8e-282 ytgP S Membrane protein involved in the export of O-antigen and teichoic acid
PANGELCK_01933 2.6e-269 murE 6.3.2.13, 6.3.2.7 M to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PANGELCK_01934 5.1e-189 femA 2.3.2.16, 2.3.2.17, 2.3.2.18 V protein involved in methicillin resistance
PANGELCK_01935 1.2e-97 yvdD 3.2.2.10 S Belongs to the LOG family
PANGELCK_01936 8.6e-57 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PANGELCK_01937 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PANGELCK_01938 8e-42 ylxQ J ribosomal protein
PANGELCK_01939 1e-47 ylxR K Nucleic-acid-binding protein implicated in transcription termination
PANGELCK_01940 2.4e-196 nusA K Participates in both transcription termination and antitermination
PANGELCK_01941 2e-80 rimP S Required for maturation of 30S ribosomal subunits
PANGELCK_01942 1.2e-177 brpA K Transcriptional
PANGELCK_01943 7.4e-89 XK27_05885 2.3.1.82 M phosphinothricin N-acetyltransferase activity
PANGELCK_01944 9.4e-77 ydiB 2.7.1.221, 5.1.1.1 M ATPase or kinase
PANGELCK_01945 1.6e-247 pbuO S permease
PANGELCK_01946 1.7e-153 yitU 3.1.3.104 S hydrolases of the HAD superfamily
PANGELCK_01947 1e-130 XK27_00940 1.2.1.70, 3.5.1.9 S Metal-dependent hydrolase
PANGELCK_01948 6.2e-169 manL 2.7.1.191 G pts system
PANGELCK_01949 3.4e-133 manY G pts system
PANGELCK_01950 5.3e-159 manN G PTS system mannose fructose sorbose family IID component
PANGELCK_01951 2.2e-66 manO S Protein conserved in bacteria
PANGELCK_01952 4.9e-174 manL 2.7.1.191 G pts system
PANGELCK_01953 2e-117 manM G pts system
PANGELCK_01954 3.3e-169 manN G PTS system mannose fructose sorbose family IID component
PANGELCK_01955 2.5e-62 manO S protein conserved in bacteria
PANGELCK_01956 6.2e-230 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PANGELCK_01957 1.5e-112
PANGELCK_01958 2.6e-247 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
PANGELCK_01959 4.4e-166 dnaI L Primosomal protein DnaI
PANGELCK_01960 2.3e-215 dnaB L Replication initiation and membrane attachment
PANGELCK_01961 3e-81 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
PANGELCK_01962 4.6e-280 T PhoQ Sensor
PANGELCK_01963 7.9e-123 T Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain
PANGELCK_01964 6.2e-91 yceD K metal-binding, possibly nucleic acid-binding protein
PANGELCK_01965 2.1e-126 rsmG 2.1.1.170 J Ribosomal RNA small subunit methyltransferase G
PANGELCK_01966 8.3e-233 P COG0168 Trk-type K transport systems, membrane components
PANGELCK_01967 3e-119 ktrA P COG0569 K transport systems, NAD-binding component
PANGELCK_01968 4.5e-149 cbiQ P cobalt transport
PANGELCK_01969 3.5e-310 ykoD P abc transporter atp-binding protein
PANGELCK_01970 3e-93 S UPF0397 protein
PANGELCK_01971 1.6e-157 salL 2.5.1.63, 2.5.1.94 S S-adenosyl-l-methionine hydroxide adenosyltransferase
PANGELCK_01972 1.8e-210 sstT E Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
PANGELCK_01973 3.6e-99 metI P ABC transporter (Permease
PANGELCK_01974 1.9e-187 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
PANGELCK_01975 7.7e-263 dapE 3.5.1.18 E COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases
PANGELCK_01976 7.8e-163 metQ M Belongs to the NlpA lipoprotein family
PANGELCK_01977 5.3e-137 ET ABC transporter substrate-binding protein
PANGELCK_01978 1.7e-128 cbiO P ABC transporter
PANGELCK_01979 1.7e-134 P cobalt transport protein
PANGELCK_01980 7.9e-177 cbiM P PDGLE domain
PANGELCK_01981 6.4e-159 ureD O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PANGELCK_01982 9.5e-112 ureG KO Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
PANGELCK_01983 2.9e-128 ureF O Required for maturation of urease via the functional incorporation of the urease nickel metallocenter
PANGELCK_01984 6.6e-78 ureE O enzyme active site formation
PANGELCK_01985 0.0 ureC 3.5.1.5 E Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family
PANGELCK_01986 7.8e-54 ureB 3.5.1.5 E Belongs to the urease beta subunit family
PANGELCK_01987 7.6e-46 ureA 3.5.1.5 E Belongs to the urease gamma subunit family
PANGELCK_01988 6.8e-95 ureI S AmiS/UreI family transporter
PANGELCK_01989 6.7e-254 S Domain of unknown function (DUF4173)
PANGELCK_01990 1.3e-54 yhaI L Membrane
PANGELCK_01991 0.0 comA V ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain
PANGELCK_01992 1.9e-153 K sequence-specific DNA binding
PANGELCK_01993 4.4e-107 bcrC 3.6.1.27 I Membrane-associated phospholipid phosphatase
PANGELCK_01994 1.3e-88 ribU U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
PANGELCK_01995 4.4e-94 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
PANGELCK_01996 2.2e-246 trkA P Potassium transporter peripheral membrane component
PANGELCK_01997 4.6e-258 trkH P Cation transport protein
PANGELCK_01998 1.4e-13 yidD M Could be involved in insertion of integral membrane proteins into the membrane
PANGELCK_01999 4.4e-132 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
PANGELCK_02000 2e-95 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
PANGELCK_02001 3.4e-121 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
PANGELCK_02002 5.9e-127 xerD L tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site
PANGELCK_02003 2.1e-85 ykuL S CBS domain
PANGELCK_02004 2.1e-96 XK27_09740 S Phosphoesterase
PANGELCK_02005 1.3e-182 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PANGELCK_02006 7.6e-149 murI 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
PANGELCK_02007 1.6e-36 yneF S UPF0154 protein
PANGELCK_02008 4.5e-89 K transcriptional regulator
PANGELCK_02009 2e-241 lysA 4.1.1.20 E Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine
PANGELCK_02010 4.2e-12 ycdA S Domain of unknown function (DUF4352)
PANGELCK_02011 2.1e-99 ybhL S Belongs to the BI1 family
PANGELCK_02012 7.3e-94 XK27_09705 6.1.1.14 S HD superfamily hydrolase
PANGELCK_02013 2.3e-128 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PANGELCK_02014 1.1e-43 acyP 3.6.1.7 C Belongs to the acylphosphatase family
PANGELCK_02015 1.4e-162 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
PANGELCK_02016 1.2e-77 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
PANGELCK_02017 2.7e-293 mltG ADL Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PANGELCK_02018 1.2e-85 XK27_09675 K histone acetyltransferase HPA2 and related acetyltransferases
PANGELCK_02019 3.4e-255 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
PANGELCK_02020 4.8e-22
PANGELCK_02021 0.0 snf 2.7.11.1 L Superfamily II DNA RNA helicases, SNF2 family'
PANGELCK_02026 2.8e-85 sigH K DNA-templated transcription, initiation
PANGELCK_02027 1.8e-134 ykuT M mechanosensitive ion channel
PANGELCK_02028 5.2e-229 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
PANGELCK_02029 1.3e-70 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
PANGELCK_02030 1.1e-308 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
PANGELCK_02031 8.4e-84 XK27_03960 S Protein of unknown function (DUF3013)
PANGELCK_02032 2.1e-76 mutT3 3.6.1.13, 3.6.1.55 L NUDIX domain
PANGELCK_02033 8.5e-176 prmA J Ribosomal protein L11 methyltransferase
PANGELCK_02034 9.1e-133 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
PANGELCK_02035 0.0 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
PANGELCK_02036 3.1e-83 nrdI F Belongs to the NrdI family
PANGELCK_02037 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
PANGELCK_02038 1.4e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
PANGELCK_02039 0.0 dex 3.2.1.11 GH66 G Glycosyl hydrolase family 66
PANGELCK_02040 4.3e-236 ilvA 4.3.1.19 E Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PANGELCK_02041 3.3e-112 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
PANGELCK_02042 3.8e-111 fnr5 K Catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
PANGELCK_02043 2.3e-191 yhjX P Major Facilitator
PANGELCK_02044 9.2e-43 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PANGELCK_02045 8.1e-84 V VanZ like family
PANGELCK_02046 3.4e-179 D nuclear chromosome segregation
PANGELCK_02047 2.2e-123 glnQ E abc transporter atp-binding protein
PANGELCK_02048 3e-271 glnP P ABC transporter
PANGELCK_02049 1.5e-152 uppP 3.6.1.27 V Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin
PANGELCK_02050 4.8e-18 S Protein of unknown function (DUF3021)
PANGELCK_02051 7.8e-124 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
PANGELCK_02052 3.9e-183 tagO 2.7.8.33, 2.7.8.35 M transferase
PANGELCK_02053 1.7e-137 sufC O ABC-type transport system involved in Fe-S cluster assembly, ATPase component
PANGELCK_02054 2e-233 sufD O assembly protein SufD
PANGELCK_02055 1e-237 sufS 2.8.1.7, 4.4.1.16 E Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PANGELCK_02056 9.4e-74 nifU C SUF system FeS assembly protein, NifU family
PANGELCK_02057 2.9e-273 sufB O assembly protein SufB
PANGELCK_02058 4.7e-26
PANGELCK_02059 3.6e-157 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
PANGELCK_02060 2.8e-182 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
PANGELCK_02061 2e-71 adcR K transcriptional
PANGELCK_02062 5.4e-135 adcC 3.6.3.35 P ABC transporter, ATP-binding protein
PANGELCK_02063 3.9e-129 adcB P ABC transporter (Permease
PANGELCK_02064 1.2e-158 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
PANGELCK_02065 0.0 ptsG 2.7.1.199, 2.7.1.201, 2.7.1.208, 2.7.1.211 G pts system
PANGELCK_02066 1.2e-157 rgfB 3.1.3.90 L Endonuclease/Exonuclease/phosphatase family
PANGELCK_02067 1.1e-256 pgi 5.3.1.9 G Belongs to the GPI family
PANGELCK_02068 4.3e-150 Z012_04635 K sequence-specific DNA binding
PANGELCK_02069 9.8e-278 V ABC transporter
PANGELCK_02070 6.1e-126 yeeN K transcriptional regulatory protein
PANGELCK_02071 1.7e-46 yajC U protein transport
PANGELCK_02072 5.3e-141 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
PANGELCK_02073 7.2e-144 cdsA 2.7.7.41 S Belongs to the CDS family
PANGELCK_02074 6.5e-232 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
PANGELCK_02075 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
PANGELCK_02076 0.0 WQ51_06230 S ABC transporter substrate binding protein
PANGELCK_02077 1.4e-142 cmpC S abc transporter atp-binding protein
PANGELCK_02078 4.9e-42 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PANGELCK_02079 2.4e-287 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
PANGELCK_02081 1.9e-44
PANGELCK_02082 5.8e-55 S TM2 domain
PANGELCK_02083 4.9e-162 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
PANGELCK_02084 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PANGELCK_02085 6.2e-20 rpmG J Belongs to the bacterial ribosomal protein bL33 family
PANGELCK_02086 2.8e-24 secE U Belongs to the SecE SEC61-gamma family
PANGELCK_02087 8.4e-96 nusG K Participates in transcription elongation, termination and antitermination
PANGELCK_02088 1.1e-62 3.1.3.27, 3.1.3.4, 3.1.3.81, 3.6.1.27 I phosphatidate phosphatase activity
PANGELCK_02089 9.5e-144 cof S Sucrose-6F-phosphate phosphohydrolase
PANGELCK_02090 2e-130 glcR K transcriptional regulator (DeoR family)
PANGELCK_02091 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
PANGELCK_02092 7.9e-71 K transcriptional
PANGELCK_02093 7.5e-225 S COG1073 Hydrolases of the alpha beta superfamily
PANGELCK_02094 2.5e-150 cylA V abc transporter atp-binding protein
PANGELCK_02095 6.2e-130 cylB V ABC-2 type transporter
PANGELCK_02096 9e-75 K COG3279 Response regulator of the LytR AlgR family
PANGELCK_02097 8.3e-30 S Protein of unknown function (DUF3021)
PANGELCK_02098 1.1e-122 mta K Transcriptional
PANGELCK_02099 8.1e-120 yhcA V abc transporter atp-binding protein
PANGELCK_02100 2.7e-206 macB_2 V FtsX-like permease family
PANGELCK_02101 9.7e-272 pncB 6.3.4.21 H Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PANGELCK_02102 4.1e-150 nadE 6.3.1.5 H Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
PANGELCK_02103 8.5e-70 yhaI S Protein of unknown function (DUF805)
PANGELCK_02104 3.5e-252 pepC 3.4.22.40 E aminopeptidase
PANGELCK_02105 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
PANGELCK_02106 4.3e-109 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
PANGELCK_02107 5.8e-94 ypsA S Belongs to the UPF0398 family
PANGELCK_02108 2.1e-36 gpsB D regulation of cell shape
PANGELCK_02109 3e-223 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
PANGELCK_02110 2.9e-274 mapZ D Early cell division protein that marks the future cell division site and supports proper FtsZ ring positioning
PANGELCK_02111 6.4e-35 L Transposase

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)