ORF_ID e_value Gene_name EC_number CAZy COGs Description
HHOFPIHL_00001 1.2e-255 dnaA L it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HHOFPIHL_00002 1.1e-206 dnaN 2.7.7.7 L Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
HHOFPIHL_00003 2e-35 yaaA S S4 domain protein YaaA
HHOFPIHL_00004 1.7e-210 recF L it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HHOFPIHL_00005 0.0 gyrB 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOFPIHL_00006 0.0 gyrA 5.99.1.3 L A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HHOFPIHL_00007 1.9e-49 rpsF J Binds together with S18 to 16S ribosomal RNA
HHOFPIHL_00008 3e-59 ssb L Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
HHOFPIHL_00009 1.2e-35 rpsR J Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HHOFPIHL_00010 4.7e-232 Q Imidazolonepropionase and related amidohydrolases
HHOFPIHL_00011 4e-303 E ABC transporter, substratebinding protein
HHOFPIHL_00012 2.4e-144
HHOFPIHL_00013 9.7e-230 Q Imidazolonepropionase and related amidohydrolases
HHOFPIHL_00014 2.8e-304 E ABC transporter, substratebinding protein
HHOFPIHL_00015 1e-99 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00016 1e-38 S response to heat
HHOFPIHL_00017 0.0 yybT T signaling protein consisting of a modified GGDEF domain and a DHH domain
HHOFPIHL_00018 7.2e-64 rplI J Binds to the 23S rRNA
HHOFPIHL_00020 6e-255 dnaB 3.6.4.12 L Participates in initiation and elongation during chromosome replication
HHOFPIHL_00021 3.8e-101 S NADPH-dependent FMN reductase
HHOFPIHL_00022 3.5e-39 yttB EGP Major facilitator Superfamily
HHOFPIHL_00023 2.7e-163 yttB EGP Major facilitator Superfamily
HHOFPIHL_00024 1.1e-22
HHOFPIHL_00025 2.8e-304 E ABC transporter, substratebinding protein
HHOFPIHL_00026 1.3e-38
HHOFPIHL_00027 5.7e-130 E Matrixin
HHOFPIHL_00029 5.7e-132 K response regulator
HHOFPIHL_00030 0.0 vicK 2.7.13.3 T Histidine kinase
HHOFPIHL_00031 7.4e-239 yycH S YycH protein
HHOFPIHL_00032 2.6e-152 yycI S YycH protein
HHOFPIHL_00033 3.4e-157 vicX 3.1.26.11 S domain protein
HHOFPIHL_00034 2.6e-104 htrA 3.4.21.107 O serine protease
HHOFPIHL_00035 1.9e-81 htrA 3.4.21.107 O serine protease
HHOFPIHL_00036 7.3e-83 rlmH 2.1.1.177 J Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HHOFPIHL_00038 3.7e-176 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00039 2.9e-134 nlhH I alpha/beta hydrolase fold
HHOFPIHL_00040 2e-177 draG 3.2.2.24 O ADP-ribosylglycohydrolase
HHOFPIHL_00041 4.5e-98 yncA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HHOFPIHL_00043 4.7e-89 cadD P Cadmium resistance transporter
HHOFPIHL_00044 8.3e-78 lipB 2.3.1.181 K Acetyltransferase (GNAT) domain
HHOFPIHL_00045 1.7e-77 gtrA S GtrA-like protein
HHOFPIHL_00046 6.8e-306 E Bacterial extracellular solute-binding proteins, family 5 Middle
HHOFPIHL_00047 5.6e-115 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00048 3.5e-233 XK27_06930 S ABC-2 family transporter protein
HHOFPIHL_00049 5.1e-132 qmcA O prohibitin homologues
HHOFPIHL_00050 5.7e-55 S protein encoded in hypervariable junctions of pilus gene clusters
HHOFPIHL_00051 6.9e-133
HHOFPIHL_00052 3.3e-80 GBS0088 S Nucleotidyltransferase
HHOFPIHL_00053 3.7e-85 yybC S Protein of unknown function (DUF2798)
HHOFPIHL_00054 8.9e-57 ydiI Q Thioesterase superfamily
HHOFPIHL_00055 1e-156 menB 4.1.3.36 H Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HHOFPIHL_00056 1.7e-143 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHOFPIHL_00057 1.9e-106 menE 6.2.1.26 H Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily
HHOFPIHL_00058 4.2e-95 S Protein of unknown function (DUF1097)
HHOFPIHL_00059 9.3e-167
HHOFPIHL_00060 2.4e-289 murE 6.3.2.13, 6.3.2.7 M Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HHOFPIHL_00061 2.2e-287 lysS 6.1.1.6 J Belongs to the class-II aminoacyl-tRNA synthetase family
HHOFPIHL_00062 5.4e-212 lmrP E Major Facilitator Superfamily
HHOFPIHL_00065 2.6e-100 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00066 3.9e-179 1.1.1.1 C nadph quinone reductase
HHOFPIHL_00067 8.9e-107 dhaS K Bacterial regulatory proteins, tetR family
HHOFPIHL_00068 1.7e-279 E amino acid
HHOFPIHL_00069 3.1e-286 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HHOFPIHL_00070 9.5e-152 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOFPIHL_00071 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00072 3.8e-137 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOFPIHL_00073 2e-174
HHOFPIHL_00074 3.4e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOFPIHL_00075 1e-107 ahpC 1.11.1.15 O Peroxiredoxin
HHOFPIHL_00076 4.8e-60
HHOFPIHL_00077 8.1e-114 ylbE GM NAD(P)H-binding
HHOFPIHL_00078 1.6e-39
HHOFPIHL_00079 8.3e-25 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00080 6.5e-24 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00083 6.9e-147 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHOFPIHL_00084 2.1e-149 U Binding-protein-dependent transport system inner membrane component
HHOFPIHL_00085 6.4e-140 U Binding-protein-dependent transport system inner membrane component
HHOFPIHL_00086 3.1e-50 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_00087 1e-26 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_00088 4.7e-120
HHOFPIHL_00089 1.9e-115 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HHOFPIHL_00090 2.3e-139 pmrB EGP Major facilitator Superfamily
HHOFPIHL_00091 6.9e-32 pmrB EGP Major facilitator Superfamily
HHOFPIHL_00092 1.8e-14 pmrB EGP Major facilitator Superfamily
HHOFPIHL_00093 1.8e-33 S COG NOG18757 non supervised orthologous group
HHOFPIHL_00094 1.2e-106 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00095 2.2e-131 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOFPIHL_00096 2e-174
HHOFPIHL_00097 3.4e-228 gltP U Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family
HHOFPIHL_00098 1e-107 ahpC 1.11.1.15 O Peroxiredoxin
HHOFPIHL_00099 4.8e-60
HHOFPIHL_00100 8.1e-114 ylbE GM NAD(P)H-binding
HHOFPIHL_00101 1.1e-45
HHOFPIHL_00102 6.6e-17 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00103 3.2e-47 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00106 1.9e-275 gnd 1.1.1.343, 1.1.1.44 H Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HHOFPIHL_00107 1e-72 K Transcriptional regulator
HHOFPIHL_00108 4.2e-77 elaA S Gnat family
HHOFPIHL_00109 4e-289 zwf 1.1.1.363, 1.1.1.49 G Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HHOFPIHL_00110 2.5e-160 aacC 2.3.1.81 V Aminoglycoside 3-N-acetyltransferase
HHOFPIHL_00111 2.2e-159 1.1.1.65 C Aldo keto reductase
HHOFPIHL_00112 3e-89
HHOFPIHL_00113 6e-216 yttB EGP Major facilitator Superfamily
HHOFPIHL_00114 4.9e-246 glpT G Major Facilitator Superfamily
HHOFPIHL_00115 5.2e-136 nfrA 1.5.1.39 C nitroreductase
HHOFPIHL_00116 5.3e-86 nrdI F Belongs to the NrdI family
HHOFPIHL_00117 1.2e-269 S ATPases associated with a variety of cellular activities
HHOFPIHL_00118 2.4e-251 lmrB EGP Major facilitator Superfamily
HHOFPIHL_00120 2e-143 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOFPIHL_00121 1.9e-175 K Transcriptional regulator, LacI family
HHOFPIHL_00122 3.3e-242 yhdP S Transporter associated domain
HHOFPIHL_00123 7.6e-61
HHOFPIHL_00124 1.4e-74 hsp O Belongs to the small heat shock protein (HSP20) family
HHOFPIHL_00125 7.1e-262 yjeM E Amino Acid
HHOFPIHL_00126 3.6e-162 ytbE 1.1.1.346 S Aldo keto reductase
HHOFPIHL_00128 0.0 yfgQ P E1-E2 ATPase
HHOFPIHL_00129 2.2e-93 M1-874 K Domain of unknown function (DUF1836)
HHOFPIHL_00130 0.0 glpQ 3.1.4.46 C phosphodiesterase
HHOFPIHL_00131 0.0 adhE 1.1.1.1, 1.2.1.10 C belongs to the iron- containing alcohol dehydrogenase family
HHOFPIHL_00132 6.1e-52 M LysM domain protein
HHOFPIHL_00133 7.2e-141 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00134 0.0 3.2.1.4, 3.2.1.78, 3.2.1.8 GH26,GH5,GH9 M Leucine-rich repeat (LRR) protein
HHOFPIHL_00135 2.1e-56 M LysM domain protein
HHOFPIHL_00137 6.5e-57 M LysM domain
HHOFPIHL_00139 2.7e-97 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00140 1.9e-166 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHOFPIHL_00141 4.2e-178 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HHOFPIHL_00142 3.6e-216 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHOFPIHL_00143 1.1e-57 DR0488 S 3D domain
HHOFPIHL_00144 6.5e-285 M Exporter of polyketide antibiotics
HHOFPIHL_00145 8.8e-167 yjjC V ABC transporter
HHOFPIHL_00146 2.5e-118 ypgQ S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOFPIHL_00147 3.7e-235 V Polysaccharide biosynthesis C-terminal domain
HHOFPIHL_00148 2.9e-289 uxaC 5.3.1.12 G glucuronate isomerase
HHOFPIHL_00149 1.4e-259 gph G MFS/sugar transport protein
HHOFPIHL_00150 0.0 yicI 3.2.1.20 GH31 G Belongs to the glycosyl hydrolase 31 family
HHOFPIHL_00151 0.0 uidA 3.2.1.31 G Belongs to the glycosyl hydrolase 2 family
HHOFPIHL_00152 0.0 mtlD 1.1.1.17, 1.1.1.57 G Mannitol dehydrogenase C-terminal domain
HHOFPIHL_00153 1.2e-168 yqhA G Aldose 1-epimerase
HHOFPIHL_00154 3.2e-121 pgm3 G Belongs to the phosphoglycerate mutase family
HHOFPIHL_00155 1.4e-189 C Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOFPIHL_00156 2.7e-304 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HHOFPIHL_00157 2.3e-170 gnd 1.1.1.343, 1.1.1.44 G Dehydrogenase
HHOFPIHL_00158 2.6e-129 kdgR K FCD domain
HHOFPIHL_00159 8.8e-214 uxuA 4.2.1.8 G Catalyzes the dehydration of D-mannonate
HHOFPIHL_00160 2.4e-184 exuR K Periplasmic binding protein domain
HHOFPIHL_00161 4.9e-279 yjmB G MFS/sugar transport protein
HHOFPIHL_00162 4.8e-309 5.1.2.7 S tagaturonate epimerase
HHOFPIHL_00163 4e-294 uxaC 5.3.1.12 G glucuronate isomerase
HHOFPIHL_00164 2.4e-226 S module of peptide synthetase
HHOFPIHL_00166 9.5e-35 EGP Major facilitator Superfamily
HHOFPIHL_00167 1.4e-195 EGP Major facilitator Superfamily
HHOFPIHL_00168 1e-16 S Protein of unknown function (DUF3278)
HHOFPIHL_00169 3.3e-15 U Bacterial surface protein 26-residue
HHOFPIHL_00170 6.6e-129
HHOFPIHL_00171 1.4e-89 ybaK J Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HHOFPIHL_00172 2e-132 gntR1 K UbiC transcription regulator-associated domain protein
HHOFPIHL_00173 2e-123 O Zinc-dependent metalloprotease
HHOFPIHL_00174 3.9e-84 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHOFPIHL_00175 1.8e-77
HHOFPIHL_00176 9.2e-141 plnC K LytTr DNA-binding domain
HHOFPIHL_00177 6.2e-241 2.7.13.3 T GHKL domain
HHOFPIHL_00178 3.1e-240 2.1.1.80, 2.7.13.3, 3.1.1.61 T protein histidine kinase activity
HHOFPIHL_00179 1.4e-133 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HHOFPIHL_00181 3.7e-173 rluA 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHOFPIHL_00182 1.1e-77 uspA T universal stress protein
HHOFPIHL_00183 1e-174 norB EGP Major Facilitator
HHOFPIHL_00184 1.7e-11 K transcriptional regulator
HHOFPIHL_00185 5e-51 K transcriptional regulator
HHOFPIHL_00186 0.0 oppA1 E ABC transporter substrate-binding protein
HHOFPIHL_00187 1e-173 oppC EP Binding-protein-dependent transport system inner membrane component
HHOFPIHL_00188 9.8e-180 oppB P ABC transporter permease
HHOFPIHL_00189 2.2e-179 oppF P Belongs to the ABC transporter superfamily
HHOFPIHL_00190 2.4e-192 oppD P Belongs to the ABC transporter superfamily
HHOFPIHL_00191 1.5e-80 ywnA K Winged helix-turn-helix transcription repressor, HrcA DNA-binding
HHOFPIHL_00192 1.6e-196 lplA 6.3.1.20 H Lipoate-protein ligase
HHOFPIHL_00193 2.3e-69
HHOFPIHL_00194 2e-48
HHOFPIHL_00195 2.3e-267 xylA 5.3.1.5 G Belongs to the xylose isomerase family
HHOFPIHL_00196 2.5e-294 xylB 2.7.1.12, 2.7.1.16, 2.7.1.17 G Xylulose kinase
HHOFPIHL_00197 2.3e-94 xylT EGP Major facilitator Superfamily
HHOFPIHL_00198 1.5e-141 xylT EGP Major facilitator Superfamily
HHOFPIHL_00200 3.3e-141 IQ reductase
HHOFPIHL_00201 1.6e-69 frataxin S Domain of unknown function (DU1801)
HHOFPIHL_00202 0.0 S membrane
HHOFPIHL_00203 3e-90 uspA T universal stress protein
HHOFPIHL_00204 4.7e-96 yxkA S Phosphatidylethanolamine-binding protein
HHOFPIHL_00205 1.4e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHOFPIHL_00206 3.9e-123 kcsA P Ion channel
HHOFPIHL_00207 2.3e-49
HHOFPIHL_00208 5.3e-169 C Aldo keto reductase
HHOFPIHL_00209 7.5e-70
HHOFPIHL_00210 1.7e-93 Z012_06855 S Acetyltransferase (GNAT) family
HHOFPIHL_00211 8.4e-252 nhaC C Na H antiporter NhaC
HHOFPIHL_00212 2.3e-190 S Membrane transport protein
HHOFPIHL_00213 7e-189 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOFPIHL_00214 2.9e-277 yufL 2.7.13.3 T Single cache domain 3
HHOFPIHL_00215 3e-125 malR3 K cheY-homologous receiver domain
HHOFPIHL_00216 8.8e-179 S ABC-2 family transporter protein
HHOFPIHL_00217 7.1e-101 XK27_06935 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00218 1.8e-124 yliE T Putative diguanylate phosphodiesterase
HHOFPIHL_00219 1.5e-94 wecD K Acetyltransferase (GNAT) family
HHOFPIHL_00220 4.7e-141 S zinc-ribbon domain
HHOFPIHL_00221 1.6e-234 S response to antibiotic
HHOFPIHL_00223 1.2e-85 F NUDIX domain
HHOFPIHL_00225 3.2e-103 padC Q Phenolic acid decarboxylase
HHOFPIHL_00226 1.8e-83 padR K Virulence activator alpha C-term
HHOFPIHL_00227 5.3e-101 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00228 4.7e-188 1.1.1.219 GM Male sterility protein
HHOFPIHL_00229 1.2e-76 elaA S Gnat family
HHOFPIHL_00230 2.1e-79 yybA 2.3.1.57 K Transcriptional regulator
HHOFPIHL_00231 6.3e-38
HHOFPIHL_00232 3.4e-92
HHOFPIHL_00233 5e-91 P Cadmium resistance transporter
HHOFPIHL_00234 3.1e-121 sirR K Helix-turn-helix diphteria tox regulatory element
HHOFPIHL_00235 1.5e-71 T Universal stress protein family
HHOFPIHL_00236 2.4e-284 mntH P H( )-stimulated, divalent metal cation uptake system
HHOFPIHL_00237 7.7e-188 guaC 1.1.1.205, 1.7.1.7 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHOFPIHL_00238 3.7e-251 purA 6.3.4.4 F Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HHOFPIHL_00239 2.2e-243 purB 4.3.2.2 F Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HHOFPIHL_00240 6.1e-97 fadR K Bacterial regulatory proteins, tetR family
HHOFPIHL_00241 3.9e-181 D Alpha beta
HHOFPIHL_00242 1.1e-147 ptp3 3.1.3.48 T Tyrosine phosphatase family
HHOFPIHL_00243 5.7e-166 I Alpha beta
HHOFPIHL_00244 0.0 O Pro-kumamolisin, activation domain
HHOFPIHL_00245 5.5e-118 S Membrane
HHOFPIHL_00246 1.8e-133 puuD S peptidase C26
HHOFPIHL_00247 5.4e-37
HHOFPIHL_00248 2.4e-113 magIII L Base excision DNA repair protein, HhH-GPD family
HHOFPIHL_00249 7.2e-294 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHOFPIHL_00250 3.2e-200 M NlpC/P60 family
HHOFPIHL_00251 1.5e-163 G Peptidase_C39 like family
HHOFPIHL_00252 1.3e-104 pncA Q Isochorismatase family
HHOFPIHL_00253 6.1e-54 K Transcriptional regulator PadR-like family
HHOFPIHL_00254 1.9e-70 XK27_06920 S Protein of unknown function (DUF1700)
HHOFPIHL_00255 4.4e-119 S Putative adhesin
HHOFPIHL_00256 1.2e-185 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHOFPIHL_00257 3e-226 fabV 1.3.1.44, 1.3.1.9 I NAD(P)H binding domain of trans-2-enoyl-CoA reductase
HHOFPIHL_00258 7.4e-74 fld C Flavodoxin
HHOFPIHL_00259 3.9e-98 K Acetyltransferase (GNAT) domain
HHOFPIHL_00260 6.8e-243 yifK E Amino acid permease
HHOFPIHL_00261 5.6e-118
HHOFPIHL_00262 5.5e-104 S WxL domain surface cell wall-binding
HHOFPIHL_00263 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00264 9.8e-225 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHOFPIHL_00265 7.9e-188 adhP 1.1.1.1 C alcohol dehydrogenase
HHOFPIHL_00266 8.8e-69 lrpA K AsnC family
HHOFPIHL_00267 2.8e-163 opuBA E ABC transporter, ATP-binding protein
HHOFPIHL_00268 1.7e-274 proWX EM Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHOFPIHL_00269 1.6e-202 yxjG 2.1.1.14 E methionine synthase, vitamin-B12 independent
HHOFPIHL_00270 5.8e-100 S NADPH-dependent FMN reductase
HHOFPIHL_00271 9.2e-73 K MarR family
HHOFPIHL_00272 1.8e-189 L Helix-turn-helix domain
HHOFPIHL_00273 0.0 pacL1 P P-type ATPase
HHOFPIHL_00275 2.8e-276 pipD E Dipeptidase
HHOFPIHL_00276 5.6e-154
HHOFPIHL_00277 6.6e-99 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HHOFPIHL_00278 1.3e-119 S Elongation factor G-binding protein, N-terminal
HHOFPIHL_00279 1.9e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_00280 1.9e-08 asnB 6.3.5.4 E Protein of unknown function (DUF3923)
HHOFPIHL_00281 4e-170 EG EamA-like transporter family
HHOFPIHL_00282 0.0 copB 3.6.3.4 P P-type ATPase
HHOFPIHL_00283 5e-78 copR K Copper transport repressor CopY TcrY
HHOFPIHL_00284 2.4e-226 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHOFPIHL_00285 1.7e-159 S reductase
HHOFPIHL_00286 0.0 ctpA 3.6.3.54 P P-type ATPase
HHOFPIHL_00287 2.5e-67 silP 1.9.3.1, 3.6.3.54 S Cupredoxin-like domain
HHOFPIHL_00289 6e-146 yxkH G Polysaccharide deacetylase
HHOFPIHL_00290 1.6e-159 xerD L Phage integrase, N-terminal SAM-like domain
HHOFPIHL_00291 4.2e-192 add 3.5.4.4 F Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HHOFPIHL_00292 0.0 oatA I Acyltransferase
HHOFPIHL_00293 5.6e-122
HHOFPIHL_00294 0.0 lai 4.2.1.53 S Myosin-crossreactive antigen
HHOFPIHL_00295 2.6e-106 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHOFPIHL_00296 3.5e-67 cdd 2.4.2.2, 3.5.4.5 F This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
HHOFPIHL_00297 1.4e-37
HHOFPIHL_00298 2.4e-94 K helix_turn_helix multiple antibiotic resistance protein
HHOFPIHL_00299 1.2e-247 xylP1 G MFS/sugar transport protein
HHOFPIHL_00300 4.6e-99 S Protein of unknown function (DUF1440)
HHOFPIHL_00301 0.0 uvrA2 L ABC transporter
HHOFPIHL_00302 5e-66 S Tautomerase enzyme
HHOFPIHL_00303 1e-263
HHOFPIHL_00304 3.8e-222
HHOFPIHL_00305 2.1e-109 opuCD P Binding-protein-dependent transport system inner membrane component
HHOFPIHL_00306 2e-177 opuCC M Periplasmic glycine betaine choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein)
HHOFPIHL_00307 8e-106 opuCB E ABC transporter permease
HHOFPIHL_00308 2.8e-224 opuCA E ABC transporter, ATP-binding protein
HHOFPIHL_00309 2.3e-44
HHOFPIHL_00310 2e-222 mdtG EGP Major facilitator Superfamily
HHOFPIHL_00311 2.5e-183 yfeX P Peroxidase
HHOFPIHL_00312 1.9e-225 patB 4.4.1.8 E Aminotransferase, class I
HHOFPIHL_00313 6.2e-109 M Protein of unknown function (DUF3737)
HHOFPIHL_00314 0.0 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOFPIHL_00315 7.4e-194 ykoT GT2 M Glycosyl transferase family 2
HHOFPIHL_00316 1.4e-248 M hydrolase, family 25
HHOFPIHL_00317 3.3e-107
HHOFPIHL_00318 3.1e-196 yubA S AI-2E family transporter
HHOFPIHL_00319 3.8e-167 yclI V FtsX-like permease family
HHOFPIHL_00320 2.9e-122 yclH V ABC transporter
HHOFPIHL_00321 0.0 malL 3.2.1.10, 3.2.1.20, 3.2.1.41 CBM48,GH13,GH31 G Alpha amylase, catalytic domain protein
HHOFPIHL_00322 8.6e-57 K Winged helix DNA-binding domain
HHOFPIHL_00323 1.1e-138 pnuC H nicotinamide mononucleotide transporter
HHOFPIHL_00324 8.2e-152 corA P CorA-like Mg2+ transporter protein
HHOFPIHL_00325 0.0 poxB 1.2.3.3, 1.2.5.1 EH Belongs to the TPP enzyme family
HHOFPIHL_00326 4.1e-66
HHOFPIHL_00327 6.5e-43
HHOFPIHL_00328 7e-248 T PhoQ Sensor
HHOFPIHL_00329 8e-131 K Transcriptional regulatory protein, C terminal
HHOFPIHL_00330 1.2e-30
HHOFPIHL_00331 2.8e-114 ylbE GM NAD(P)H-binding
HHOFPIHL_00332 6.5e-229 ndh 1.6.99.3 C NADH dehydrogenase
HHOFPIHL_00333 8.1e-96 ogt 2.1.1.63, 3.2.2.20 L Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HHOFPIHL_00334 7.5e-103 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00335 1.1e-267 gabD 1.2.1.16, 1.2.1.20, 1.2.1.79 C Belongs to the aldehyde dehydrogenase family
HHOFPIHL_00336 4.2e-101 K Bacterial transcriptional regulator
HHOFPIHL_00337 1.8e-09
HHOFPIHL_00338 1.3e-146 kduI 5.3.1.17 G Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
HHOFPIHL_00339 1.2e-138 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOFPIHL_00340 7e-128 kdgT P 2-keto-3-deoxygluconate permease
HHOFPIHL_00341 8.2e-110 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HHOFPIHL_00342 4.2e-81 eda 4.1.2.14, 4.1.3.42 G KDPG and KHG aldolase
HHOFPIHL_00343 8e-129 IQ reductase
HHOFPIHL_00344 6.4e-241 mntH P H( )-stimulated, divalent metal cation uptake system
HHOFPIHL_00345 8.2e-154 S Uncharacterised protein, DegV family COG1307
HHOFPIHL_00346 2.5e-269 nox C NADH oxidase
HHOFPIHL_00347 2.3e-56 trxA1 O Belongs to the thioredoxin family
HHOFPIHL_00348 1.3e-38 yrkD S Metal-sensitive transcriptional repressor
HHOFPIHL_00349 3.5e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOFPIHL_00350 5.4e-59 crcB U Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HHOFPIHL_00351 4.2e-150 M1-1017
HHOFPIHL_00352 8.7e-164 I Carboxylesterase family
HHOFPIHL_00353 3.3e-88 luxS 4.4.1.21 H Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)
HHOFPIHL_00354 4.5e-165
HHOFPIHL_00355 5.5e-250 pts14C G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOFPIHL_00356 2.1e-168 S Alpha/beta hydrolase of unknown function (DUF915)
HHOFPIHL_00357 1e-156 lysR5 K LysR substrate binding domain
HHOFPIHL_00358 9e-145 yxaA S membrane transporter protein
HHOFPIHL_00359 5.4e-57 ywjH S Protein of unknown function (DUF1634)
HHOFPIHL_00360 1.3e-139 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HHOFPIHL_00361 6.8e-226 mdtG EGP Major facilitator Superfamily
HHOFPIHL_00362 5.7e-94 2.7.6.5 S RelA SpoT domain protein
HHOFPIHL_00363 8.1e-28 S Protein of unknown function (DUF2929)
HHOFPIHL_00364 5.5e-169 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHOFPIHL_00366 0.0 S membrane
HHOFPIHL_00367 8.5e-125 K cheY-homologous receiver domain
HHOFPIHL_00368 1.1e-245 ciaH 2.7.13.3 T His Kinase A (phosphoacceptor) domain
HHOFPIHL_00369 1.8e-181 malR K Transcriptional regulator, LacI family
HHOFPIHL_00370 4.5e-255 malT G Major Facilitator
HHOFPIHL_00371 0.0 mapA 2.4.1.8 GH65 G hydrolase, family 65, central catalytic
HHOFPIHL_00372 2.4e-77
HHOFPIHL_00373 6e-42 rpsN J Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HHOFPIHL_00374 4.2e-152 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHOFPIHL_00375 2.1e-162 S Alpha/beta hydrolase of unknown function (DUF915)
HHOFPIHL_00376 9.6e-152 3.1.3.102, 3.1.3.104 S Sucrose-6F-phosphate phosphohydrolase
HHOFPIHL_00377 4.6e-64 K MarR family
HHOFPIHL_00378 8.4e-249 yclG M Parallel beta-helix repeats
HHOFPIHL_00379 2.7e-73 spx4 1.20.4.1 P ArsC family
HHOFPIHL_00380 5.9e-143 iap CBM50 M NlpC/P60 family
HHOFPIHL_00381 1.7e-47 K acetyltransferase
HHOFPIHL_00382 2.4e-31 K acetyltransferase
HHOFPIHL_00383 5.1e-298 E dipeptidase activity
HHOFPIHL_00384 6.9e-69 S membrane transporter protein
HHOFPIHL_00385 1.6e-49 S membrane transporter protein
HHOFPIHL_00386 1.8e-21 IQ Enoyl-(Acyl carrier protein) reductase
HHOFPIHL_00387 3.3e-77 IQ Enoyl-(Acyl carrier protein) reductase
HHOFPIHL_00388 1.8e-226 G Major Facilitator
HHOFPIHL_00389 0.0 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HHOFPIHL_00390 3e-153 3.2.1.37 GH43 K helix_turn_helix, arabinose operon control protein
HHOFPIHL_00391 1.6e-132 IQ Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
HHOFPIHL_00392 1.7e-151 1.6.5.2 GM NmrA-like family
HHOFPIHL_00393 1.4e-72 K Transcriptional regulator
HHOFPIHL_00394 0.0 2.7.8.12 M glycerophosphotransferase
HHOFPIHL_00395 3.1e-170
HHOFPIHL_00396 6.3e-63 K Transcriptional regulator, HxlR family
HHOFPIHL_00397 3.9e-202 ytbD EGP Major facilitator Superfamily
HHOFPIHL_00398 7.2e-183 S Aldo keto reductase
HHOFPIHL_00399 1.8e-136 cysA V ABC transporter, ATP-binding protein
HHOFPIHL_00400 0.0 Q FtsX-like permease family
HHOFPIHL_00401 1.3e-60 gntR1 K Transcriptional regulator, GntR family
HHOFPIHL_00402 5e-69 S Iron-sulphur cluster biosynthesis
HHOFPIHL_00403 2.4e-184 sdrF M Collagen binding domain
HHOFPIHL_00404 0.0 cadA P P-type ATPase
HHOFPIHL_00405 5.6e-121 S SNARE associated Golgi protein
HHOFPIHL_00406 0.0 mco Q Multicopper oxidase
HHOFPIHL_00407 9.4e-53 czrA K Transcriptional regulator, ArsR family
HHOFPIHL_00408 3.6e-103 P Cadmium resistance transporter
HHOFPIHL_00409 2.9e-161 MA20_14895 S Conserved hypothetical protein 698
HHOFPIHL_00410 2.9e-154 K LysR substrate binding domain
HHOFPIHL_00411 3.9e-210 norA EGP Major facilitator Superfamily
HHOFPIHL_00412 5.9e-160 K helix_turn_helix, arabinose operon control protein
HHOFPIHL_00413 4.5e-311 ybiT S ABC transporter, ATP-binding protein
HHOFPIHL_00414 5.8e-169 ydcZ S Putative inner membrane exporter, YdcZ
HHOFPIHL_00415 8.7e-181 xopQ 3.2.2.1, 3.2.2.8 F inosine-uridine preferring nucleoside hydrolase
HHOFPIHL_00416 1.4e-25
HHOFPIHL_00417 0.0 2.8.2.22 M Arylsulfotransferase Ig-like domain
HHOFPIHL_00418 3.2e-135 XK27_07210 6.1.1.6 S B3/4 domain
HHOFPIHL_00419 1.9e-127 S Protein of unknown function (DUF975)
HHOFPIHL_00420 7.2e-62 ytrA K helix_turn_helix gluconate operon transcriptional repressor
HHOFPIHL_00421 1.7e-162 ytrB V ABC transporter, ATP-binding protein
HHOFPIHL_00422 8.4e-176
HHOFPIHL_00423 1.3e-193 KT Putative sugar diacid recognition
HHOFPIHL_00424 2.8e-214 EG GntP family permease
HHOFPIHL_00425 2e-208 glxK 2.7.1.165 G Belongs to the glycerate kinase type-1 family
HHOFPIHL_00426 1.8e-53 ydbT S Bacterial PH domain
HHOFPIHL_00427 1.3e-188 ydbT S Bacterial PH domain
HHOFPIHL_00428 7.8e-85 S Bacterial PH domain
HHOFPIHL_00429 4.9e-78 2.4.2.6 F Nucleoside 2-deoxyribosyltransferase
HHOFPIHL_00430 1.6e-255 U Belongs to the purine-cytosine permease (2.A.39) family
HHOFPIHL_00431 9.8e-36
HHOFPIHL_00432 4.1e-278 frvR K Mga helix-turn-helix domain
HHOFPIHL_00433 6.1e-252 S Uncharacterized protein conserved in bacteria (DUF2252)
HHOFPIHL_00434 1.6e-61 K Winged helix DNA-binding domain
HHOFPIHL_00435 8.2e-32
HHOFPIHL_00436 4.1e-240 mntH P H( )-stimulated, divalent metal cation uptake system
HHOFPIHL_00437 5.8e-241 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHOFPIHL_00439 3e-98 I NUDIX domain
HHOFPIHL_00440 2.8e-114 yviA S Protein of unknown function (DUF421)
HHOFPIHL_00441 4.4e-74 S Protein of unknown function (DUF3290)
HHOFPIHL_00442 3e-167 ropB K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00443 8.8e-221 EGP Major facilitator Superfamily
HHOFPIHL_00444 9.8e-255 gshR 1.8.1.7 C Glutathione reductase
HHOFPIHL_00445 9.1e-36 ygbF S Sugar efflux transporter for intercellular exchange
HHOFPIHL_00446 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00447 7.5e-198 napA P Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
HHOFPIHL_00448 1e-35
HHOFPIHL_00449 1.5e-138 kguE 2.7.1.45 G Xylose isomerase domain protein TIM barrel
HHOFPIHL_00450 1.3e-233 gntT EG Citrate transporter
HHOFPIHL_00451 3.7e-179 kdgK 2.7.1.45 G pfkB family carbohydrate kinase
HHOFPIHL_00452 3.8e-108 hxlA 4.1.2.43 G Orotidine 5'-phosphate decarboxylase HUMPS family
HHOFPIHL_00453 1.3e-88 hxlB 4.1.2.14, 4.1.2.43, 4.1.3.42, 5.3.1.27 M sugar phosphate isomerase involved in capsule formation
HHOFPIHL_00454 5.2e-176 kdgR K helix_turn _helix lactose operon repressor
HHOFPIHL_00455 4.3e-55
HHOFPIHL_00456 1.4e-83
HHOFPIHL_00457 0.0 helD 3.6.4.12 L DNA helicase
HHOFPIHL_00458 1.2e-191 trpS 6.1.1.2 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHOFPIHL_00459 5.7e-169 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHOFPIHL_00460 1.3e-227 mvaA 1.1.1.34, 1.1.1.88, 2.3.1.9 C Belongs to the HMG-CoA reductase family
HHOFPIHL_00461 4.9e-179
HHOFPIHL_00462 1.8e-130 cobB K SIR2 family
HHOFPIHL_00463 3.8e-51
HHOFPIHL_00464 2.1e-162 yunF F Protein of unknown function DUF72
HHOFPIHL_00465 0.0 metG 6.1.1.10, 6.1.1.20 J Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HHOFPIHL_00466 1.8e-147 tatD L hydrolase, TatD family
HHOFPIHL_00467 4.3e-98 rnmV 3.1.26.8 J Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
HHOFPIHL_00468 1.3e-162 ksgA 2.1.1.182 J Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
HHOFPIHL_00469 4.3e-36 veg S Biofilm formation stimulator VEG
HHOFPIHL_00470 1.9e-163 ispE 2.1.1.182, 2.7.1.148 F Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HHOFPIHL_00471 1.2e-108 ung2 3.2.2.27 L Uracil-DNA glycosylase
HHOFPIHL_00472 0.0 yicI 3.2.1.177 GH31 G Belongs to the glycosyl hydrolase 31 family
HHOFPIHL_00473 2.8e-260 xylP G MFS/sugar transport protein
HHOFPIHL_00474 3.1e-212 xylR GK ROK family
HHOFPIHL_00475 8.5e-292 celA 3.2.1.86 GT1 G Belongs to the glycosyl hydrolase 1 family
HHOFPIHL_00476 1.7e-160 2.7.1.2 GK ROK family
HHOFPIHL_00477 7.4e-91
HHOFPIHL_00479 4.3e-154 S Prolyl oligopeptidase family
HHOFPIHL_00480 1.1e-162 znuA P Belongs to the bacterial solute-binding protein 9 family
HHOFPIHL_00481 2.7e-131 fhuC P ABC transporter
HHOFPIHL_00482 8.2e-132 znuB U ABC 3 transport family
HHOFPIHL_00485 4.4e-144 purR 2.4.2.22, 2.4.2.7 F pur operon repressor
HHOFPIHL_00486 3.8e-217 glmU 2.3.1.157, 2.7.7.23 M Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HHOFPIHL_00487 5.5e-178 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOFPIHL_00488 9.7e-56 S Domain of unknown function (DUF3899)
HHOFPIHL_00489 3.6e-70 racA K helix_turn_helix, mercury resistance
HHOFPIHL_00490 1.7e-131 gntR K UbiC transcription regulator-associated domain protein
HHOFPIHL_00491 0.0 xpkA 4.1.2.22, 4.1.2.9 G Phosphoketolase
HHOFPIHL_00492 1.8e-189 L Helix-turn-helix domain
HHOFPIHL_00493 9.3e-147 yxeH S hydrolase
HHOFPIHL_00494 8.7e-267 ywfO S HD domain protein
HHOFPIHL_00495 4.3e-155 lipL 2.3.1.200, 2.3.1.204 H biotin lipoate A B protein ligase
HHOFPIHL_00496 1.7e-78 ywiB S Domain of unknown function (DUF1934)
HHOFPIHL_00497 5.8e-54 rpoE K Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling
HHOFPIHL_00498 6.7e-311 pyrG 6.3.4.2 F Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
HHOFPIHL_00499 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00500 3.7e-246
HHOFPIHL_00501 2.7e-73 K Transcriptional regulator
HHOFPIHL_00502 0.0 alsS 2.2.1.6 EH Belongs to the TPP enzyme family
HHOFPIHL_00503 4e-130 budA 4.1.1.5 H Belongs to the alpha-acetolactate decarboxylase family
HHOFPIHL_00504 0.0 pelX UW LPXTG-motif cell wall anchor domain protein
HHOFPIHL_00505 2.8e-238 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHOFPIHL_00506 4.3e-42 rpmE2 J Ribosomal protein L31
HHOFPIHL_00507 8.7e-117 srtA 3.4.22.70 M sortase family
HHOFPIHL_00508 5.7e-18 S WxL domain surface cell wall-binding
HHOFPIHL_00509 3.4e-08 S WxL domain surface cell wall-binding
HHOFPIHL_00510 6.6e-07 S WxL domain surface cell wall-binding
HHOFPIHL_00511 6.9e-81 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00513 4.2e-15 S WxL domain surface cell wall-binding
HHOFPIHL_00514 2.8e-32 S WxL domain surface cell wall-binding
HHOFPIHL_00515 9.8e-109 S Cell surface protein
HHOFPIHL_00516 9e-58 XK27_00720 S regulation of response to stimulus
HHOFPIHL_00517 6.5e-80 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00518 2.5e-252 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00519 5.3e-86 ptpA 3.1.3.48 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHOFPIHL_00520 9.9e-95 lemA S LemA family
HHOFPIHL_00521 1.6e-147 htpX O Belongs to the peptidase M48B family
HHOFPIHL_00522 8.6e-150
HHOFPIHL_00523 2.4e-256 murF 6.3.2.10 M Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein
HHOFPIHL_00524 1.6e-240 cshA 3.6.4.13 F DEAD-box RNA helicase possibly involved in RNA degradation. Unwinds dsRNA in both 5'- and 3'-directions, has RNA- dependent ATPase activity
HHOFPIHL_00525 2.1e-213 S nuclear-transcribed mRNA catabolic process, no-go decay
HHOFPIHL_00526 2.9e-63 acpS 2.7.6.3, 2.7.8.7, 5.1.1.1 I Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein
HHOFPIHL_00527 4.6e-213 alr 5.1.1.1 E Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HHOFPIHL_00529 3.6e-61 ndoA L Toxic component of a toxin-antitoxin (TA) module
HHOFPIHL_00530 1.1e-113 S (CBS) domain
HHOFPIHL_00532 1.9e-256 S Putative peptidoglycan binding domain
HHOFPIHL_00533 2.2e-176 ldh 1.1.1.27 C Belongs to the LDH MDH superfamily. LDH family
HHOFPIHL_00534 1e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_00535 8.7e-104 pth 3.1.1.29 J The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis
HHOFPIHL_00536 0.0 mfd L Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HHOFPIHL_00537 2e-294 yabM S Polysaccharide biosynthesis protein
HHOFPIHL_00538 1.6e-39 yabO J S4 domain protein
HHOFPIHL_00539 9.7e-44 divIC D Septum formation initiator
HHOFPIHL_00540 4.2e-71 yabR J RNA binding
HHOFPIHL_00541 5.7e-258 tilS 2.4.2.8, 6.3.4.19 J Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
HHOFPIHL_00542 1.3e-96 hpt 2.4.2.8 F Belongs to the purine pyrimidine phosphoribosyltransferase family
HHOFPIHL_00543 0.0 ftsH O Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HHOFPIHL_00544 2.6e-163 hslO O Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HHOFPIHL_00545 1.5e-194 dus J Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HHOFPIHL_00550 7.6e-52 2.7.1.196, 2.7.1.205 G PTS system, Lactose/Cellobiose specific IIB subunit
HHOFPIHL_00551 1.3e-298 dtpT U amino acid peptide transporter
HHOFPIHL_00552 7.2e-149 yjjH S Calcineurin-like phosphoesterase
HHOFPIHL_00555 3.3e-136 proC 1.5.1.2 E Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HHOFPIHL_00556 1.1e-217 nagA 3.5.1.25 G Belongs to the metallo-dependent hydrolases superfamily. NagA family
HHOFPIHL_00557 2.5e-124 gntR1 K UbiC transcription regulator-associated domain protein
HHOFPIHL_00558 2.3e-95 MA20_25245 K FR47-like protein
HHOFPIHL_00559 5.3e-141 tagA 2.4.1.187 GT26 F Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid
HHOFPIHL_00560 4.8e-287 pncB 6.3.4.21 F Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
HHOFPIHL_00561 1.6e-154 nadE 6.3.1.5 F Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source
HHOFPIHL_00562 1.4e-72
HHOFPIHL_00563 0.0 yhgF K Tex-like protein N-terminal domain protein
HHOFPIHL_00564 4e-89 ydcK S Belongs to the SprT family
HHOFPIHL_00565 3.1e-156 thrB 2.7.1.39 F Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate
HHOFPIHL_00567 3.1e-47 4.1.1.52, 4.2.1.83 E amidohydrolase
HHOFPIHL_00568 5.5e-18 yobS K transcriptional regulator
HHOFPIHL_00569 1.6e-100 S Psort location CytoplasmicMembrane, score
HHOFPIHL_00570 6.6e-75 K MarR family
HHOFPIHL_00571 3e-246 dinF V MatE
HHOFPIHL_00572 1.8e-110 gph 3.1.3.18 S HAD hydrolase, family IA, variant
HHOFPIHL_00573 4.3e-55 manL 2.7.1.191 G PTS system fructose IIA component
HHOFPIHL_00574 6.9e-60 pts10B 2.7.1.191, 2.7.1.202 G PTS system sorbose subfamily IIB component
HHOFPIHL_00575 1.1e-117 manM G PTS system
HHOFPIHL_00576 2.5e-155 manN G system, mannose fructose sorbose family IID component
HHOFPIHL_00577 2.2e-177 K AI-2E family transporter
HHOFPIHL_00578 2.7e-168 2.7.7.65 T diguanylate cyclase
HHOFPIHL_00579 1.9e-118 yliE T EAL domain
HHOFPIHL_00580 2.8e-102 K Bacterial regulatory proteins, tetR family
HHOFPIHL_00581 2.4e-102 XK27_06930 V domain protein
HHOFPIHL_00582 8.1e-129 XK27_06930 V domain protein
HHOFPIHL_00583 2.4e-167 znuA P Belongs to the bacterial solute-binding protein 9 family
HHOFPIHL_00584 5.3e-175 L Integrase core domain
HHOFPIHL_00585 7.8e-205 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHOFPIHL_00586 2.4e-107 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HHOFPIHL_00587 1.8e-45 mleP2 S Transporter, auxin efflux carrier (AEC) family protein
HHOFPIHL_00588 1.3e-174 EG EamA-like transporter family
HHOFPIHL_00589 1.5e-123 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHOFPIHL_00590 4.5e-230 V Beta-lactamase
HHOFPIHL_00591 5e-259 pepC 3.4.22.40 E Peptidase C1-like family
HHOFPIHL_00593 5.3e-127 rpiA 2.7.1.12, 5.3.1.6 G Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HHOFPIHL_00594 4.1e-56
HHOFPIHL_00595 8.7e-101 dut 3.6.1.23, 4.1.1.36, 6.3.2.5 F dUTP diphosphatase
HHOFPIHL_00596 1.1e-256 radA O DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HHOFPIHL_00597 3.7e-213 yacL S domain protein
HHOFPIHL_00598 3.1e-289 gltX 6.1.1.17, 6.1.1.24 J Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HHOFPIHL_00599 7.4e-277 cysS 6.1.1.16, 6.3.1.13 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHOFPIHL_00600 7.8e-70 mrnC J Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HHOFPIHL_00601 2.5e-138 rlmB 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOFPIHL_00602 1.8e-90 yacP S YacP-like NYN domain
HHOFPIHL_00603 1.5e-98 sigH K Sigma-70 region 2
HHOFPIHL_00604 3.3e-25 secE U Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
HHOFPIHL_00605 1.1e-98 nusG K Participates in transcription elongation, termination and antitermination
HHOFPIHL_00606 3.7e-70 rplK J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HHOFPIHL_00607 1.2e-123 rplA J Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release
HHOFPIHL_00608 6.9e-84 rplJ J Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HHOFPIHL_00609 4e-49 rplL J Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation
HHOFPIHL_00610 0.0 mprF 2.3.2.3 S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHOFPIHL_00611 1.1e-109 yvdD 3.2.2.10 S Belongs to the LOG family
HHOFPIHL_00612 1.3e-170 fadB4 1.1.1.157 I 3-hydroxyacyl-CoA dehydrogenase
HHOFPIHL_00613 8.5e-195 nrdF 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOFPIHL_00614 0.0 nrdE 1.17.4.1 F Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HHOFPIHL_00615 4.9e-37 nrdH O Glutaredoxin
HHOFPIHL_00616 1.9e-112 rsmC 2.1.1.172 J Methyltransferase
HHOFPIHL_00617 9.8e-92 tadA 3.5.4.33 F Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)
HHOFPIHL_00618 0.0 dnaX 2.7.7.7 L DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOFPIHL_00619 1.5e-39 yaaK S Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HHOFPIHL_00620 8.7e-110 recR L May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HHOFPIHL_00621 1.3e-38 yaaL S Protein of unknown function (DUF2508)
HHOFPIHL_00622 2.1e-112 tmk 2.7.4.9 F Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HHOFPIHL_00623 2.2e-54 yaaQ S Cyclic-di-AMP receptor
HHOFPIHL_00624 3.2e-181 holB 2.7.7.7 L DNA polymerase III
HHOFPIHL_00625 1.7e-38 yabA L Involved in initiation control of chromosome replication
HHOFPIHL_00626 1.2e-154 rsmI 2.1.1.198 H Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HHOFPIHL_00627 4e-141 fat 3.1.2.21 I Acyl-ACP thioesterase
HHOFPIHL_00628 3.2e-127 yeaZ 2.3.1.234 O Universal bacterial protein YeaZ
HHOFPIHL_00629 1.8e-110 rimI 2.3.1.128 K Ribosomal-protein-alanine acetyltransferase
HHOFPIHL_00630 1.4e-195 tsaD 2.3.1.234 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HHOFPIHL_00631 2.3e-215 yeaN P Transporter, major facilitator family protein
HHOFPIHL_00632 7.5e-46 cadC1 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHOFPIHL_00633 0.0 uup S ABC transporter, ATP-binding protein
HHOFPIHL_00634 6.9e-113 rex K Modulates transcription in response to changes in cellular NADH NAD( ) redox state
HHOFPIHL_00635 3e-44 groS O Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HHOFPIHL_00636 6.5e-293 groL O Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions
HHOFPIHL_00637 0.0 ydaO E amino acid
HHOFPIHL_00638 3.7e-140 lrgB M LrgB-like family
HHOFPIHL_00639 1.6e-60 lrgA S LrgA family
HHOFPIHL_00640 3.6e-178 tagO 2.7.8.33, 2.7.8.35 M transferase
HHOFPIHL_00641 1.1e-116 yvyE 3.4.13.9 S YigZ family
HHOFPIHL_00642 1.5e-255 comFA L Helicase C-terminal domain protein
HHOFPIHL_00643 1.1e-124 comFC S Competence protein
HHOFPIHL_00644 7.9e-97 hpf J Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HHOFPIHL_00645 0.0 secA U Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
HHOFPIHL_00646 8.6e-187 prfB J Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HHOFPIHL_00647 1e-223 minJ O Domain present in PSD-95, Dlg, and ZO-1/2.
HHOFPIHL_00648 2e-129 K response regulator
HHOFPIHL_00649 1.1e-248 phoR 2.7.13.3 T Histidine kinase
HHOFPIHL_00650 2.5e-161 pstS P Phosphate
HHOFPIHL_00651 2e-158 pstC P probably responsible for the translocation of the substrate across the membrane
HHOFPIHL_00652 2.2e-154 pstA P Phosphate transport system permease protein PstA
HHOFPIHL_00653 1.8e-150 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOFPIHL_00654 1.3e-139 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOFPIHL_00655 1.4e-119 phoU P Plays a role in the regulation of phosphate uptake
HHOFPIHL_00656 1.7e-54 pspC KT PspC domain protein
HHOFPIHL_00657 5.5e-30 yvlD S Mycobacterial 4 TMS phage holin, superfamily IV
HHOFPIHL_00658 9.5e-172 hprK F Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
HHOFPIHL_00659 1.1e-150 lgt 2.1.1.199 M Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HHOFPIHL_00660 1.5e-183 gpsA 1.1.1.94 I Glycerol-3-phosphate dehydrogenase
HHOFPIHL_00661 5.6e-169 galU 2.7.7.9 M UTP-glucose-1-phosphate uridylyltransferase
HHOFPIHL_00662 4.5e-177 trxB 1.8.1.9 C Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family
HHOFPIHL_00664 3.3e-115 yfbR S HD containing hydrolase-like enzyme
HHOFPIHL_00665 4.5e-94 K acetyltransferase
HHOFPIHL_00666 0.0 uvrB L damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
HHOFPIHL_00667 0.0 uvrA L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
HHOFPIHL_00668 2.4e-90 S Short repeat of unknown function (DUF308)
HHOFPIHL_00669 1.7e-76 rapZ S Displays ATPase and GTPase activities
HHOFPIHL_00670 2.8e-66 rapZ S Displays ATPase and GTPase activities
HHOFPIHL_00671 3.4e-191 ybhK S Required for morphogenesis under gluconeogenic growth conditions
HHOFPIHL_00672 9.9e-169 whiA K May be required for sporulation
HHOFPIHL_00673 1.7e-102 clpP 3.4.21.92 O Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
HHOFPIHL_00674 2.6e-74 XK27_02470 K LytTr DNA-binding domain
HHOFPIHL_00675 1.6e-126 liaI S membrane
HHOFPIHL_00677 1.4e-107 S ECF transporter, substrate-specific component
HHOFPIHL_00679 7.5e-186 cggR K Putative sugar-binding domain
HHOFPIHL_00680 9e-192 gap 1.2.1.12 G Belongs to the glyceraldehyde-3-phosphate dehydrogenase family
HHOFPIHL_00681 4.3e-225 pgk 2.7.2.3, 5.3.1.1 F Belongs to the phosphoglycerate kinase family
HHOFPIHL_00682 2.3e-139 tpiA 2.7.2.3, 5.3.1.1 G Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
HHOFPIHL_00683 6.1e-249 eno 4.2.1.11 G Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
HHOFPIHL_00685 3.9e-287 clcA P chloride
HHOFPIHL_00686 4.9e-32 secG U Preprotein translocase
HHOFPIHL_00687 7.8e-140 est 3.1.1.1 S Serine aminopeptidase, S33
HHOFPIHL_00688 0.0 rnr J 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs
HHOFPIHL_00689 2.3e-81 smpB J the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA
HHOFPIHL_00690 1.2e-132 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHOFPIHL_00691 4.4e-103 yxjI
HHOFPIHL_00692 1.8e-141 ung 3.2.2.27 L Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HHOFPIHL_00693 1.1e-178 pta 2.3.1.8, 3.6.3.21 C phosphate acetyltransferase
HHOFPIHL_00694 1.1e-83 ydiB 2.7.1.221, 5.1.1.1 O Hydrolase, P-loop family
HHOFPIHL_00695 1.4e-87 2.3.1.128, 2.3.1.178 J Acetyltransferase (GNAT) domain
HHOFPIHL_00696 3e-195 C Aldo keto reductase family protein
HHOFPIHL_00697 6e-102 dnaQ 2.7.7.7 L DNA polymerase III
HHOFPIHL_00698 2.4e-152 xth 3.1.11.2 L exodeoxyribonuclease III
HHOFPIHL_00699 5e-165 murB 1.3.1.98 M Cell wall formation
HHOFPIHL_00700 0.0 yjcE P Sodium proton antiporter
HHOFPIHL_00701 1.2e-123 S Protein of unknown function (DUF1361)
HHOFPIHL_00702 4.5e-152 dacA 2.7.7.85 S Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HHOFPIHL_00703 1.8e-133 ybbR S YbbR-like protein
HHOFPIHL_00704 1.1e-253 glmM 5.4.2.10 G Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HHOFPIHL_00705 0.0 glmS 2.6.1.16 M Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source
HHOFPIHL_00706 1.7e-12
HHOFPIHL_00707 9.1e-130 nagB 3.1.1.31, 3.5.99.6 G Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion
HHOFPIHL_00708 2.2e-252 NU Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase
HHOFPIHL_00709 0.0 cadA 3.6.3.3, 3.6.3.5 P P-type ATPase
HHOFPIHL_00710 4.1e-98 dps P Belongs to the Dps family
HHOFPIHL_00711 1.1e-25 copZ P Heavy-metal-associated domain
HHOFPIHL_00712 7.9e-202 tagH 3.6.3.38, 3.6.3.40 GM Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system
HHOFPIHL_00713 6.2e-51
HHOFPIHL_00714 2.1e-63 S Iron Transport-associated domain
HHOFPIHL_00715 1.8e-178 M Iron Transport-associated domain
HHOFPIHL_00716 5.2e-91 M Iron Transport-associated domain
HHOFPIHL_00717 1.2e-163 isdE P Periplasmic binding protein
HHOFPIHL_00718 9.9e-172 isdF U Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HHOFPIHL_00719 7.8e-140 fhuC 3.6.3.34 HP ABC transporter, ATP-binding protein
HHOFPIHL_00720 2.4e-170 ppx 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHOFPIHL_00721 0.0 ppk 2.7.4.1 P Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HHOFPIHL_00722 6.4e-290 ppx3 3.6.1.11, 3.6.1.40 FP exopolyphosphatase
HHOFPIHL_00723 1.6e-151 licD M LicD family
HHOFPIHL_00724 2.9e-78 S Domain of unknown function (DUF5067)
HHOFPIHL_00725 3.9e-75 K Transcriptional regulator
HHOFPIHL_00726 1.9e-25
HHOFPIHL_00727 2.7e-79 O OsmC-like protein
HHOFPIHL_00728 8.3e-24
HHOFPIHL_00730 6.5e-55 ypaA S Protein of unknown function (DUF1304)
HHOFPIHL_00731 1.3e-35
HHOFPIHL_00732 9.9e-39
HHOFPIHL_00733 3.8e-257 fumC 4.2.1.2 C Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
HHOFPIHL_00734 1.8e-259 dapE 3.5.1.18 E Peptidase dimerisation domain
HHOFPIHL_00735 5e-91 K helix_turn _helix lactose operon repressor
HHOFPIHL_00736 9.8e-103 S Putative glutamine amidotransferase
HHOFPIHL_00737 1.3e-134 S protein conserved in bacteria
HHOFPIHL_00738 1.6e-151 pac 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HHOFPIHL_00739 2.3e-237 arcA 3.5.3.6 E Arginine
HHOFPIHL_00740 2.8e-45
HHOFPIHL_00743 9e-147 K response regulator
HHOFPIHL_00744 3.5e-269 T PhoQ Sensor
HHOFPIHL_00745 1.5e-211 ywbD 2.1.1.191 J S-adenosylmethionine-dependent methyltransferase
HHOFPIHL_00746 1.3e-154 glcU U sugar transport
HHOFPIHL_00747 7.1e-261 pgi 5.3.1.9 G Belongs to the GPI family
HHOFPIHL_00748 0.0 S Bacterial membrane protein YfhO
HHOFPIHL_00749 5.2e-81 tspO T TspO/MBR family
HHOFPIHL_00750 3.8e-99 S Protein of unknown function (DUF1211)
HHOFPIHL_00753 2.2e-163 S NAD:arginine ADP-ribosyltransferase
HHOFPIHL_00754 1.1e-170 ybiR P Citrate transporter
HHOFPIHL_00755 2.1e-120 yliE T Putative diguanylate phosphodiesterase
HHOFPIHL_00756 1.4e-175 L Integrase core domain
HHOFPIHL_00757 1.8e-53 2.7.7.65 T diguanylate cyclase activity
HHOFPIHL_00758 9.8e-177 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_00759 2.5e-152 2.7.7.65 T diguanylate cyclase
HHOFPIHL_00760 8.7e-09
HHOFPIHL_00761 8.9e-56
HHOFPIHL_00762 0.0 lmrA V ABC transporter, ATP-binding protein
HHOFPIHL_00763 0.0 yfiC V ABC transporter
HHOFPIHL_00764 5.5e-197 ampC V Beta-lactamase
HHOFPIHL_00765 1e-133 cobQ S glutamine amidotransferase
HHOFPIHL_00766 1.4e-264 murD 3.4.21.10, 6.3.2.13, 6.3.2.9 M Mur ligase, middle domain
HHOFPIHL_00767 8.5e-110 tdk 2.7.1.21 F thymidine kinase
HHOFPIHL_00768 5.5e-187 prfA J Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HHOFPIHL_00769 1.8e-156 prmB 2.1.1.297, 2.1.1.298 J Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif
HHOFPIHL_00770 6.5e-190 ywlC 2.7.7.87, 3.1.3.48 J Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine
HHOFPIHL_00771 4.2e-141 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHOFPIHL_00772 5.7e-77 glyA 2.1.2.1 E Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HHOFPIHL_00773 3e-113 upp 2.4.2.9 F Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HHOFPIHL_00774 6.1e-126 atpB C it plays a direct role in the translocation of protons across the membrane
HHOFPIHL_00775 7.3e-27 atpE C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOFPIHL_00776 1.6e-56 atpF C Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HHOFPIHL_00777 2e-89 atpH C F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HHOFPIHL_00778 1.7e-287 atpA 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HHOFPIHL_00779 7.3e-161 atpG C Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HHOFPIHL_00780 1.4e-267 atpD 3.6.3.14 C Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HHOFPIHL_00781 8.3e-67 atpC C Produces ATP from ADP in the presence of a proton gradient across the membrane
HHOFPIHL_00782 4.3e-33 ywzB S Protein of unknown function (DUF1146)
HHOFPIHL_00783 5.9e-244 murA 2.5.1.7 M Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HHOFPIHL_00784 4.6e-180 mbl D Cell shape determining protein MreB Mrl
HHOFPIHL_00785 1.1e-52 yidD S Could be involved in insertion of integral membrane proteins into the membrane
HHOFPIHL_00786 1.1e-33 S Protein of unknown function (DUF2969)
HHOFPIHL_00787 1.1e-220 rodA D Belongs to the SEDS family
HHOFPIHL_00788 1.9e-49 gcsH2 E glycine cleavage
HHOFPIHL_00789 9.3e-142 f42a O Band 7 protein
HHOFPIHL_00790 4.2e-178 S Protein of unknown function (DUF2785)
HHOFPIHL_00791 1.8e-217 ddl 6.3.2.4 F Belongs to the D-alanine--D-alanine ligase family
HHOFPIHL_00792 1.1e-305 glpQ 3.1.4.46 C Glycerophosphoryl diester phosphodiesterase family
HHOFPIHL_00793 7.9e-160 2.3.1.19 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_00794 1e-81 usp6 T universal stress protein
HHOFPIHL_00795 3.2e-41
HHOFPIHL_00796 2.1e-238 rarA L recombination factor protein RarA
HHOFPIHL_00797 1.9e-80 yueI S Protein of unknown function (DUF1694)
HHOFPIHL_00798 1.3e-113 yktB S Belongs to the UPF0637 family
HHOFPIHL_00799 7.1e-61 KLT serine threonine protein kinase
HHOFPIHL_00800 9.7e-109 rpsD J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HHOFPIHL_00801 2.4e-83 ytsP 1.8.4.14 T GAF domain-containing protein
HHOFPIHL_00802 0.0 ezrA D modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
HHOFPIHL_00803 3.8e-215 iscS2 2.8.1.7 E Aminotransferase class V
HHOFPIHL_00804 1.9e-228 thiI 2.8.1.4 H Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HHOFPIHL_00805 1.1e-89 tpx 1.11.1.15 O Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HHOFPIHL_00806 0.0 valS 6.1.1.9 J amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
HHOFPIHL_00807 2.1e-249 folC 6.3.2.12, 6.3.2.17 H Belongs to the folylpolyglutamate synthase family
HHOFPIHL_00808 5.6e-118 radC L DNA repair protein
HHOFPIHL_00809 9.6e-162 mreB D cell shape determining protein MreB
HHOFPIHL_00810 9.7e-139 mreC M Involved in formation and maintenance of cell shape
HHOFPIHL_00811 3.2e-92 mreD M rod shape-determining protein MreD
HHOFPIHL_00812 2.8e-117 minC D Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization
HHOFPIHL_00813 4.1e-147 minD D Belongs to the ParA family
HHOFPIHL_00814 2.5e-110 glnP P ABC transporter permease
HHOFPIHL_00815 4.2e-94 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHOFPIHL_00816 1.3e-159 aatB ET ABC transporter substrate-binding protein
HHOFPIHL_00817 6e-233 ymfF S Peptidase M16 inactive domain protein
HHOFPIHL_00818 4.4e-244 ymfH S Peptidase M16
HHOFPIHL_00819 1.3e-64 ymfM S Domain of unknown function (DUF4115)
HHOFPIHL_00820 1e-99 pgsA 2.7.8.41, 2.7.8.5 I Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HHOFPIHL_00821 1.6e-227 cinA 3.5.1.42 S Belongs to the CinA family
HHOFPIHL_00822 4.7e-189 recA L Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HHOFPIHL_00823 1e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_00825 4e-223 rny S Endoribonuclease that initiates mRNA decay
HHOFPIHL_00826 3e-150 ymdB S YmdB-like protein
HHOFPIHL_00827 0.0 mutS L that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HHOFPIHL_00828 0.0 mutL L This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HHOFPIHL_00829 2.8e-108 ruvA 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
HHOFPIHL_00830 1.2e-188 ruvB 3.6.4.12 L The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
HHOFPIHL_00831 4.1e-200 queA 2.4.99.17 J Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HHOFPIHL_00832 1.2e-227 tgt 2.4.2.29 F Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
HHOFPIHL_00833 1.1e-26 yajC U Preprotein translocase
HHOFPIHL_00834 3.5e-181 dinB 2.7.7.7 L Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HHOFPIHL_00835 9.9e-180 nrnA 3.1.13.3, 3.1.3.7 S DHHA1 domain protein
HHOFPIHL_00836 6.1e-252 cshB 3.6.4.13 JKL DEAD-box RNA helicase. May work in conjunction with the cold shock proteins to ensure proper initiation of transcription at low and optimal temperatures
HHOFPIHL_00837 0.0 alaS 6.1.1.7 J Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HHOFPIHL_00838 6.4e-44 yrzL S Belongs to the UPF0297 family
HHOFPIHL_00839 1.5e-74 yqgF J Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HHOFPIHL_00840 1.6e-51 yrzB S Belongs to the UPF0473 family
HHOFPIHL_00841 1.2e-39 zapA D Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
HHOFPIHL_00842 1.4e-87 cvpA S Colicin V production protein
HHOFPIHL_00843 0.0 mutS2 L Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity
HHOFPIHL_00844 2.7e-54 trxA O Belongs to the thioredoxin family
HHOFPIHL_00845 7.2e-92 yslB S Protein of unknown function (DUF2507)
HHOFPIHL_00846 2.2e-148 murI 3.6.1.66, 5.1.1.3 M Provides the (R)-glutamate required for cell wall biosynthesis
HHOFPIHL_00847 6.2e-108 rdgB 3.6.1.66, 5.1.1.3 F Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HHOFPIHL_00848 5.4e-100 S Phosphoesterase
HHOFPIHL_00849 4.4e-65 ykuL S (CBS) domain
HHOFPIHL_00851 4.7e-48 K helix_turn_helix, Arsenical Resistance Operon Repressor
HHOFPIHL_00852 4.1e-156 ykuT M mechanosensitive ion channel
HHOFPIHL_00853 6.9e-34 WQ51_05790 S protein containing a divergent version of the methyl-accepting chemotaxis-like domain
HHOFPIHL_00854 9.5e-43
HHOFPIHL_00855 2.7e-210 pepQ 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHOFPIHL_00856 1.6e-180 ccpA K catabolite control protein A
HHOFPIHL_00857 2.7e-133
HHOFPIHL_00858 5.7e-135 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHOFPIHL_00859 9.5e-267 glnPH2 P ABC transporter permease
HHOFPIHL_00860 2.6e-132 yebC K Transcriptional regulatory protein
HHOFPIHL_00861 1.2e-172 comGA NU Type II IV secretion system protein
HHOFPIHL_00862 3.1e-170 comGB NU type II secretion system
HHOFPIHL_00863 7.6e-49 comGC U competence protein ComGC
HHOFPIHL_00864 3.4e-82
HHOFPIHL_00866 1.1e-74
HHOFPIHL_00867 1.5e-186 ytxK 2.1.1.72 L N-6 DNA Methylase
HHOFPIHL_00868 1.1e-220 ackA 2.7.2.1 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHOFPIHL_00869 4.2e-90 cycA E Amino acid permease
HHOFPIHL_00870 4.3e-158 cycA E Amino acid permease
HHOFPIHL_00871 1.5e-155 yeaE S Aldo keto
HHOFPIHL_00872 5.3e-115 S Calcineurin-like phosphoesterase
HHOFPIHL_00873 2.3e-270 yunD 3.1.3.5 F Belongs to the 5'-nucleotidase family
HHOFPIHL_00874 1.1e-86 yutD S Protein of unknown function (DUF1027)
HHOFPIHL_00875 1.5e-146 nagD 2.7.1.25, 3.1.3.41 G Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro
HHOFPIHL_00876 7.7e-117 S Protein of unknown function (DUF1461)
HHOFPIHL_00877 6.9e-89 S WxL domain surface cell wall-binding
HHOFPIHL_00878 0.0 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_00879 2.8e-268 M domain protein
HHOFPIHL_00880 1.8e-251 yfnA E Amino Acid
HHOFPIHL_00881 3.6e-143 IQ Oxidoreductase, short chain dehydrogenase reductase family protein
HHOFPIHL_00882 2.9e-122 dedA S SNARE-like domain protein
HHOFPIHL_00883 6.1e-88 pgpA 3.1.3.27 I Phosphatidylglycerophosphatase A
HHOFPIHL_00884 3.5e-111 ppiB 5.2.1.8 G PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HHOFPIHL_00885 5.2e-71 yugI 5.3.1.9 J general stress protein
HHOFPIHL_00894 1.2e-07
HHOFPIHL_00904 7.3e-233 N Uncharacterized conserved protein (DUF2075)
HHOFPIHL_00905 1.8e-92 traP 1.14.99.57, 6.2.1.3 S enzyme involved in biosynthesis of extracellular polysaccharides
HHOFPIHL_00906 8.4e-139 yhfI S Metallo-beta-lactamase superfamily
HHOFPIHL_00907 1e-69 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHOFPIHL_00908 1.7e-120 mecA NOT Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis
HHOFPIHL_00909 9.5e-104 T EAL domain
HHOFPIHL_00910 1.7e-90
HHOFPIHL_00911 8.5e-251 pgaC GT2 M Glycosyl transferase
HHOFPIHL_00913 3.7e-102 ytqB J Putative rRNA methylase
HHOFPIHL_00914 3e-116 pgpB1 3.6.1.27 I Acid phosphatase homologues
HHOFPIHL_00915 0.0 leuS 6.1.1.4 J Belongs to the class-I aminoacyl-tRNA synthetase family
HHOFPIHL_00916 2.2e-122 P ABC-type multidrug transport system ATPase component
HHOFPIHL_00917 4.8e-145 S NADPH-dependent FMN reductase
HHOFPIHL_00918 4.4e-52
HHOFPIHL_00919 8.8e-298 ytgP S Polysaccharide biosynthesis protein
HHOFPIHL_00920 1.3e-125 rluB 5.4.99.19, 5.4.99.20, 5.4.99.21, 5.4.99.22 J pseudouridine synthase activity
HHOFPIHL_00921 1.3e-148 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HHOFPIHL_00922 2.4e-272 pepV 3.5.1.18 E dipeptidase PepV
HHOFPIHL_00923 8.2e-85 uspA T Belongs to the universal stress protein A family
HHOFPIHL_00924 1.2e-202 ald 1.4.1.1 C Belongs to the AlaDH PNT family
HHOFPIHL_00925 1.6e-244 cycA E Amino acid permease
HHOFPIHL_00926 2e-55 ytzB S Small secreted protein
HHOFPIHL_00927 4e-56 ytpP 2.7.1.180, 5.3.4.1 CO Thioredoxin
HHOFPIHL_00928 3.1e-113 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOFPIHL_00929 0.0 sftA D Belongs to the FtsK SpoIIIE SftA family
HHOFPIHL_00930 4.3e-258 mpl 6.3.2.4, 6.3.2.45, 6.3.2.8 M Belongs to the MurCDEF family
HHOFPIHL_00931 6.2e-134 pnuC H nicotinamide mononucleotide transporter
HHOFPIHL_00932 7.1e-119 ybhL S Belongs to the BI1 family
HHOFPIHL_00933 1.9e-237 F Permease
HHOFPIHL_00934 4.4e-263 guaD 3.5.4.3 F Amidohydrolase family
HHOFPIHL_00935 0.0 polA 2.7.7.7 L In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HHOFPIHL_00936 2.3e-164 fpg 3.2.2.23, 4.2.99.18 L Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
HHOFPIHL_00937 2.8e-111 coaE 2.7.1.24 F Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HHOFPIHL_00938 7.8e-88 nrdR K Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HHOFPIHL_00939 4.9e-249 dnaB L replication initiation and membrane attachment
HHOFPIHL_00940 1.3e-165 dnaI L Primosomal protein DnaI
HHOFPIHL_00941 0.0 thrS 6.1.1.3 J Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HHOFPIHL_00942 1.3e-78 infC J IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HHOFPIHL_00943 5.1e-27 rpmI J Belongs to the bacterial ribosomal protein bL35 family
HHOFPIHL_00944 3.7e-55 rplT J Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HHOFPIHL_00945 3.2e-103 yqeG S HAD phosphatase, family IIIA
HHOFPIHL_00946 8.5e-223 yqeH S Ribosome biogenesis GTPase YqeH
HHOFPIHL_00947 1.3e-48 yhbY J RNA-binding protein
HHOFPIHL_00948 5.9e-117 nadD 2.7.7.18, 3.6.1.55 H Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HHOFPIHL_00949 7.3e-109 nadD 2.7.6.3, 2.7.7.18 H Hydrolase, HD family
HHOFPIHL_00950 5.4e-59 rsfS J Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
HHOFPIHL_00951 5.9e-140 yqeM Q Methyltransferase
HHOFPIHL_00952 2.9e-215 ylbM S Belongs to the UPF0348 family
HHOFPIHL_00953 8.6e-96 yceD S Uncharacterized ACR, COG1399
HHOFPIHL_00954 6.9e-29 rpmF J Belongs to the bacterial ribosomal protein bL32 family
HHOFPIHL_00955 4.9e-148 3.1.3.23 S Sucrose-6F-phosphate phosphohydrolase
HHOFPIHL_00956 7.4e-52 K Transcriptional regulator, ArsR family
HHOFPIHL_00957 5.4e-113 zmp3 O Zinc-dependent metalloprotease
HHOFPIHL_00958 1.6e-230 L Transposase
HHOFPIHL_00959 1.9e-194 adhP 1.1.1.1 C alcohol dehydrogenase
HHOFPIHL_00960 2.8e-120 K response regulator
HHOFPIHL_00961 7.1e-292 arlS 2.7.13.3 T Histidine kinase
HHOFPIHL_00962 9.2e-71 S Protein of unknown function (DUF1093)
HHOFPIHL_00963 3.1e-135 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOFPIHL_00964 8.4e-44 acyP 3.6.1.7 C Belongs to the acylphosphatase family
HHOFPIHL_00965 9.4e-141 spoU 2.1.1.185 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HHOFPIHL_00966 4e-92 2.7.7.19, 2.7.7.72 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOFPIHL_00967 3.9e-68 yodB K Transcriptional regulator, HxlR family
HHOFPIHL_00968 5.8e-202 pheS 6.1.1.20 J Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HHOFPIHL_00969 0.0 pheT 6.1.1.20 J Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily
HHOFPIHL_00970 5e-207 mltG S Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HHOFPIHL_00971 1e-119 udk 2.7.1.48 F Cytidine monophosphokinase
HHOFPIHL_00972 6.3e-71 greA K Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
HHOFPIHL_00973 1.7e-56 yneR S Belongs to the HesB IscA family
HHOFPIHL_00974 0.0 S membrane
HHOFPIHL_00975 4.2e-27 CP_0775 S Domain of unknown function (DUF378)
HHOFPIHL_00976 0.0 pbp2b 3.4.16.4 M Penicillin-binding Protein
HHOFPIHL_00977 2.5e-21 rpmG J Belongs to the bacterial ribosomal protein bL33 family
HHOFPIHL_00978 7e-98 ygfA 6.3.3.2 H Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HHOFPIHL_00979 4e-119 gluP 3.4.21.105 S Peptidase, S54 family
HHOFPIHL_00980 9.3e-36 yqgQ S Bacterial protein of unknown function (DUF910)
HHOFPIHL_00981 8.9e-181 glk 2.7.1.2 G Glucokinase
HHOFPIHL_00982 2.1e-70 yqhL P Rhodanese-like protein
HHOFPIHL_00983 3.1e-23 WQ51_02665 S Protein of unknown function (DUF3042)
HHOFPIHL_00984 1.9e-141 glpQ 3.1.4.46 C phosphodiesterase
HHOFPIHL_00985 1.2e-171 miaA 2.5.1.75 F Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HHOFPIHL_00986 2.1e-64 glnR K Transcriptional regulator
HHOFPIHL_00987 2.6e-263 glnA 6.3.1.2 E glutamine synthetase
HHOFPIHL_00988 8.1e-157
HHOFPIHL_00989 1.8e-178
HHOFPIHL_00990 6.5e-96 dut S Protein conserved in bacteria
HHOFPIHL_00991 4.1e-95 K Transcriptional regulator
HHOFPIHL_00992 3.4e-49 rplU J This protein binds to 23S rRNA in the presence of protein L20
HHOFPIHL_00993 2.2e-57 ysxB J Cysteine protease Prp
HHOFPIHL_00994 1.6e-48 rpmA J Belongs to the bacterial ribosomal protein bL27 family
HHOFPIHL_00995 2.8e-191 pepP 3.4.11.9, 3.4.13.9 E Creatinase/Prolidase N-terminal domain
HHOFPIHL_00996 1.3e-99 efp J Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HHOFPIHL_00997 4.8e-73 yqhY S Asp23 family, cell envelope-related function
HHOFPIHL_00998 7.2e-74 nusB K Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HHOFPIHL_00999 6.2e-157 folD 1.5.1.5, 3.5.4.9 F Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HHOFPIHL_01000 2.5e-245 xseA 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOFPIHL_01001 2.9e-35 xseB 3.1.11.6 L Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
HHOFPIHL_01002 2.9e-165 ispA 2.5.1.1, 2.5.1.10, 2.5.1.29, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHOFPIHL_01003 2.9e-148 rrmJ 2.1.1.226, 2.1.1.227 J Ribosomal RNA large subunit methyltransferase J
HHOFPIHL_01004 3.7e-76 argR K Regulates arginine biosynthesis genes
HHOFPIHL_01005 2.6e-308 recN L May be involved in recombinational repair of damaged DNA
HHOFPIHL_01007 4.9e-51
HHOFPIHL_01008 3.3e-104 gmk 2.7.4.8 F Essential for recycling GMP and indirectly, cGMP
HHOFPIHL_01009 4.9e-31 rpoZ 2.7.7.6 K Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
HHOFPIHL_01010 7.9e-211 coaBC 4.1.1.36, 6.3.2.5 H Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HHOFPIHL_01011 0.0 priA L Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HHOFPIHL_01012 1.5e-172 fmt 2.1.2.9 J Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HHOFPIHL_01013 1.6e-228 sun 2.1.1.176 J Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HHOFPIHL_01014 7.7e-132 stp 3.1.3.16 T phosphatase
HHOFPIHL_01015 0.0 prkC 2.7.11.1 KLT serine threonine protein kinase
HHOFPIHL_01016 6.1e-168 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHOFPIHL_01017 1.1e-118 rpe 5.1.3.1 G Belongs to the ribulose-phosphate 3-epimerase family
HHOFPIHL_01018 4.7e-128 thiN 2.7.6.2 H thiamine pyrophosphokinase
HHOFPIHL_01019 4.9e-27 rpmB J Belongs to the bacterial ribosomal protein bL28 family
HHOFPIHL_01020 5.2e-57 asp S Asp23 family, cell envelope-related function
HHOFPIHL_01021 0.0 yloV S DAK2 domain fusion protein YloV
HHOFPIHL_01022 0.0 recG 3.6.4.12 L Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HHOFPIHL_01023 4.7e-188 plsX 2.3.1.15 I Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
HHOFPIHL_01024 6.4e-38 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOFPIHL_01025 2.8e-128 rnc 3.1.26.3 J Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
HHOFPIHL_01026 0.0 smc D Required for chromosome condensation and partitioning
HHOFPIHL_01027 3.6e-173 ftsY U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HHOFPIHL_01028 2.9e-57 ylxM S Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
HHOFPIHL_01029 6.4e-207 ffh 3.6.5.4 U Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HHOFPIHL_01030 0.0 pacL 3.6.3.8 P P-type ATPase
HHOFPIHL_01031 1.8e-215 3.1.3.1 S associated with various cellular activities
HHOFPIHL_01032 4.5e-252 S Putative metallopeptidase domain
HHOFPIHL_01033 2.1e-48
HHOFPIHL_01034 3.8e-44 rpsP J Belongs to the bacterial ribosomal protein bS16 family
HHOFPIHL_01035 1.9e-40 ylqC S Belongs to the UPF0109 family
HHOFPIHL_01036 1.2e-91 rimM J An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HHOFPIHL_01037 1.6e-108 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHOFPIHL_01038 1.1e-26 trmD 2.1.1.228, 4.6.1.12 J Belongs to the RNA methyltransferase TrmD family
HHOFPIHL_01039 2.7e-58 rplS J This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
HHOFPIHL_01040 7.2e-15 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOFPIHL_01041 2.3e-75 fabZ 3.5.1.108, 4.2.1.59 I Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
HHOFPIHL_01042 2.1e-79 marR K Transcriptional regulator
HHOFPIHL_01043 1.7e-182 fabH 2.3.1.180 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HHOFPIHL_01044 2e-36 acpP IQ Carrier of the growing fatty acid chain in fatty acid biosynthesis
HHOFPIHL_01045 2.2e-165 fabD 2.3.1.39 I Malonyl CoA-acyl carrier protein transacylase
HHOFPIHL_01046 3.2e-122 IQ reductase
HHOFPIHL_01047 1.1e-228 fabF 2.3.1.179 I Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
HHOFPIHL_01048 3e-72 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHOFPIHL_01049 3.8e-72 fabZ 3.5.1.108, 4.2.1.59 I FabA-like domain
HHOFPIHL_01050 1.2e-266 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HHOFPIHL_01051 4.2e-155 accD 2.1.3.15, 6.4.1.2 I Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HHOFPIHL_01052 5.9e-143 accA 2.1.3.15, 6.4.1.2 I alpha subunit
HHOFPIHL_01053 5.3e-128 fabI 1.3.1.10, 1.3.1.9 I Enoyl- acyl-carrier-protein reductase NADH
HHOFPIHL_01054 8.4e-145 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHOFPIHL_01055 6.5e-85 bioY S BioY family
HHOFPIHL_01056 2e-52 yvdC S MazG nucleotide pyrophosphohydrolase domain
HHOFPIHL_01057 1.1e-92 entB 3.5.1.19 Q Isochorismatase family
HHOFPIHL_01058 6.1e-79 S Protein of unknown function (DUF3021)
HHOFPIHL_01059 8.7e-75 K LytTr DNA-binding domain
HHOFPIHL_01060 2.4e-50 N PFAM Uncharacterised protein family UPF0150
HHOFPIHL_01061 1.3e-176 S Cysteine-rich secretory protein family
HHOFPIHL_01064 1.4e-118 ydeA 3.5.1.124 S DJ-1/PfpI family
HHOFPIHL_01065 2.3e-209 1.1.1.90 C Zn-dependent alcohol dehydrogenases, class III
HHOFPIHL_01066 1.7e-148 K LysR substrate binding domain
HHOFPIHL_01067 1.6e-26 adhR K MerR, DNA binding
HHOFPIHL_01068 8.9e-192 C Aldo/keto reductase family
HHOFPIHL_01069 4e-198 rsgA 3.1.3.100 S One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit
HHOFPIHL_01070 2.3e-78 katA 1.11.1.6 C Belongs to the catalase family
HHOFPIHL_01071 1e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_01072 1.8e-197 katA 1.11.1.6 C Belongs to the catalase family
HHOFPIHL_01073 2.1e-102 rimL J Acetyltransferase (GNAT) domain
HHOFPIHL_01074 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_01075 6.2e-70
HHOFPIHL_01076 1.5e-10 K Bacterial regulatory proteins, tetR family
HHOFPIHL_01077 2.2e-148 K Helix-turn-helix
HHOFPIHL_01078 7.7e-280 yjeM E Amino Acid
HHOFPIHL_01079 6.3e-276 pipD E Dipeptidase
HHOFPIHL_01080 1.1e-154 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHOFPIHL_01081 1.4e-26 dmpI 5.3.2.6 G Belongs to the 4-oxalocrotonate tautomerase family
HHOFPIHL_01082 9.9e-296 glpK 2.7.1.30 F Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HHOFPIHL_01084 5.3e-56 S Protein of unknown function (DUF2975)
HHOFPIHL_01085 3.7e-28 yozG K Transcriptional regulator
HHOFPIHL_01086 2e-201
HHOFPIHL_01087 6.3e-100
HHOFPIHL_01088 1.5e-203 ica2 GT2 M Glycosyl transferase family group 2
HHOFPIHL_01089 6.3e-60 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOFPIHL_01090 8.5e-114 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOFPIHL_01091 0.0 yhcA V ABC transporter, ATP-binding protein
HHOFPIHL_01092 5.6e-59 bm3R1 K Psort location Cytoplasmic, score
HHOFPIHL_01093 4.5e-70 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHOFPIHL_01094 1.7e-38 S Mor transcription activator family
HHOFPIHL_01095 2.9e-41 S Mor transcription activator family
HHOFPIHL_01096 5.8e-126 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHOFPIHL_01097 1.4e-19 S Mor transcription activator family
HHOFPIHL_01098 8.6e-128 ybhF_2 V AAA domain, putative AbiEii toxin, Type IV TA system
HHOFPIHL_01099 1.1e-169 ybhR V ABC transporter
HHOFPIHL_01100 1.3e-111 K Bacterial regulatory proteins, tetR family
HHOFPIHL_01101 4e-177 lctO C L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases
HHOFPIHL_01102 5.4e-59 yqkB S Belongs to the HesB IscA family
HHOFPIHL_01103 2e-162 yjcE P Sodium proton antiporter
HHOFPIHL_01104 3.9e-19 yjcE P Sodium proton antiporter
HHOFPIHL_01105 3.6e-28 yeaN P Major Facilitator Superfamily
HHOFPIHL_01106 0.0 kup P Transport of potassium into the cell
HHOFPIHL_01107 3.9e-184 C Zinc-binding dehydrogenase
HHOFPIHL_01108 3.1e-18 1.1.1.219 GM Male sterility protein
HHOFPIHL_01109 2.6e-73 1.1.1.219 GM Male sterility protein
HHOFPIHL_01110 3.8e-78 K helix_turn_helix, mercury resistance
HHOFPIHL_01111 7.2e-66 K MarR family
HHOFPIHL_01112 4.3e-49 S Uncharacterized protein conserved in bacteria (DUF2316)
HHOFPIHL_01113 3e-198 adh 1.1.1.1, 1.1.1.14 E alcohol dehydrogenase
HHOFPIHL_01114 3.6e-39 K Transcriptional regulator
HHOFPIHL_01115 7.4e-30 K Transcriptional regulator
HHOFPIHL_01116 2.6e-163 akr5f 1.1.1.346 S reductase
HHOFPIHL_01117 4.2e-166 S Oxidoreductase, aldo keto reductase family protein
HHOFPIHL_01118 1e-81
HHOFPIHL_01119 3.9e-215 dapE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHOFPIHL_01120 3e-153 yitU 3.1.3.104 S hydrolase
HHOFPIHL_01121 1.6e-268 rsmF 2.1.1.176, 2.1.1.178 J NOL1 NOP2 sun family protein
HHOFPIHL_01122 2.3e-190 fni 1.1.1.88, 5.3.3.2 C Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP)
HHOFPIHL_01123 6.4e-204 mvaK2 2.7.1.36, 2.7.1.43, 2.7.4.2 I phosphomevalonate kinase
HHOFPIHL_01124 1.5e-175 mvaD 4.1.1.33 I diphosphomevalonate decarboxylase
HHOFPIHL_01125 2.5e-172 mvk 1.1.1.88, 2.3.3.10, 2.7.1.36 I mevalonate kinase
HHOFPIHL_01126 0.0 dinG 2.7.7.7, 3.6.4.12 L helicase involved in DNA repair and perhaps also replication
HHOFPIHL_01127 2.6e-83 ypmB S Protein conserved in bacteria
HHOFPIHL_01128 1.3e-65 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HHOFPIHL_01129 2.9e-134 aspB 2.6.1.1, 2.6.1.14 E Aminotransferase
HHOFPIHL_01130 5.5e-124 dnaD L Replication initiation and membrane attachment
HHOFPIHL_01131 1.3e-90 yetL K helix_turn_helix multiple antibiotic resistance protein
HHOFPIHL_01132 3.5e-61 P Rhodanese Homology Domain
HHOFPIHL_01133 0.0 ponA 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein 1A
HHOFPIHL_01134 1.4e-112 recU L Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation
HHOFPIHL_01135 5e-107 ypsA S Belongs to the UPF0398 family
HHOFPIHL_01136 6.4e-28 gpsB D Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation
HHOFPIHL_01138 3.6e-221 rlmL 2.1.1.173, 2.1.1.264 L Belongs to the methyltransferase superfamily
HHOFPIHL_01139 2.3e-68 FG Scavenger mRNA decapping enzyme C-term binding
HHOFPIHL_01140 5.3e-248 amtB P ammonium transporter
HHOFPIHL_01141 4.8e-28
HHOFPIHL_01142 9.7e-84 mutT 3.6.1.55 F Belongs to the Nudix hydrolase family
HHOFPIHL_01143 4e-54
HHOFPIHL_01144 9.7e-126 S CAAX protease self-immunity
HHOFPIHL_01145 3.4e-86 K Bacterial regulatory proteins, tetR family
HHOFPIHL_01146 1.6e-111 XK27_02070 S Nitroreductase family
HHOFPIHL_01147 5.9e-50 yurR 1.4.5.1 E FAD dependent oxidoreductase
HHOFPIHL_01148 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_01149 1.6e-143 yurR 1.4.5.1 E FAD dependent oxidoreductase
HHOFPIHL_01150 6.8e-66 rnhA 3.1.26.4 L Ribonuclease HI
HHOFPIHL_01151 2.4e-56 esbA S Family of unknown function (DUF5322)
HHOFPIHL_01152 6.2e-307 fhs 6.3.4.3 F Belongs to the formate--tetrahydrofolate ligase family
HHOFPIHL_01153 5.7e-81 lspA 3.4.23.36 MU This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HHOFPIHL_01154 2.7e-171 rluD 5.4.99.23 J Responsible for synthesis of pseudouridine from uracil
HHOFPIHL_01155 6.8e-90 pyrR 2.4.2.9 F Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HHOFPIHL_01156 1.5e-205 carA 6.3.5.5 F Belongs to the CarA family
HHOFPIHL_01157 0.0 carB 6.3.5.5 F Carbamoyl-phosphate synthase
HHOFPIHL_01158 0.0 FbpA K Fibronectin-binding protein
HHOFPIHL_01159 8.2e-70 K Transcriptional regulator
HHOFPIHL_01160 1.3e-198 npp S type I phosphodiesterase nucleotide pyrophosphatase
HHOFPIHL_01161 9e-234 yxiO S Vacuole effluxer Atg22 like
HHOFPIHL_01162 3.9e-159 degV S EDD domain protein, DegV family
HHOFPIHL_01163 3.2e-87 folT S ECF transporter, substrate-specific component
HHOFPIHL_01164 5.1e-75 gtcA S Teichoic acid glycosylation protein
HHOFPIHL_01165 3e-87 ysaA V VanZ like family
HHOFPIHL_01166 6.9e-92 V VanZ like family
HHOFPIHL_01167 8.5e-119 nth 4.2.99.18 L DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HHOFPIHL_01168 4.5e-146 mta K helix_turn_helix, mercury resistance
HHOFPIHL_01169 1.1e-178 C Zinc-binding dehydrogenase
HHOFPIHL_01170 5e-150 pphA 3.1.3.16 T Calcineurin-like phosphoesterase
HHOFPIHL_01171 6.2e-132 Q Methyltransferase domain
HHOFPIHL_01172 3.5e-46
HHOFPIHL_01173 1.6e-199 xerS L Belongs to the 'phage' integrase family
HHOFPIHL_01174 4.6e-76 3.6.1.55 F NUDIX domain
HHOFPIHL_01175 1.9e-100 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOFPIHL_01176 1.3e-81 msrB 1.8.4.11, 1.8.4.12 O peptide methionine sulfoxide reductase
HHOFPIHL_01177 4.2e-101 zmp1 O PFAM peptidase M10A and M12B, matrixin and adamalysin
HHOFPIHL_01178 3.7e-168 ppaC 3.6.1.1 C inorganic pyrophosphatase
HHOFPIHL_01179 1.6e-182 K Transcriptional regulator
HHOFPIHL_01180 0.0 parC 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOFPIHL_01181 0.0 parE 5.99.1.3 L Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
HHOFPIHL_01182 1.2e-98 plsY 2.3.1.15, 3.5.1.104 I Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
HHOFPIHL_01183 1.9e-169 lacX 5.1.3.3 G Aldose 1-epimerase
HHOFPIHL_01184 1.8e-262 hslU O this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HHOFPIHL_01185 1.8e-93 hslV 3.4.25.2 O Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HHOFPIHL_01186 5.8e-177 xerC D Belongs to the 'phage' integrase family. XerC subfamily
HHOFPIHL_01187 0.0 topA 5.99.1.2 L Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HHOFPIHL_01188 1.8e-167 dprA LU DNA protecting protein DprA
HHOFPIHL_01189 3.3e-136 rnhB 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHOFPIHL_01190 1.5e-158 ylqF S Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HHOFPIHL_01192 4.1e-74 abiGI K Psort location Cytoplasmic, score
HHOFPIHL_01195 5.7e-129
HHOFPIHL_01196 5.8e-35 yozE S Belongs to the UPF0346 family
HHOFPIHL_01197 6.5e-105 ypmS S Uncharacterized protein conserved in bacteria (DUF2140)
HHOFPIHL_01198 1.2e-166 ypmR E GDSL-like Lipase/Acylhydrolase
HHOFPIHL_01199 2.3e-148 DegV S EDD domain protein, DegV family
HHOFPIHL_01200 4.9e-111 hlyIII S protein, hemolysin III
HHOFPIHL_01201 7.4e-91 folA 1.5.1.3 H Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HHOFPIHL_01202 2.8e-187 thyA 2.1.1.45 F Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HHOFPIHL_01203 0.0 yfmR S ABC transporter, ATP-binding protein
HHOFPIHL_01204 1.7e-218 cca 2.7.7.19, 2.7.7.72 J Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HHOFPIHL_01205 1.3e-171 ypjC S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHOFPIHL_01206 1.1e-231 S Tetratricopeptide repeat protein
HHOFPIHL_01207 1.5e-40 hup L Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
HHOFPIHL_01208 6.7e-248 der 1.1.1.399, 1.1.1.95 S GTPase that plays an essential role in the late steps of ribosome biogenesis
HHOFPIHL_01209 1.1e-210 rpsA 1.17.7.4 J Ribosomal protein S1
HHOFPIHL_01210 6.4e-117 cmk 1.17.7.4, 2.5.1.19, 2.7.1.26, 2.7.4.25, 2.7.7.2, 6.3.2.1 F Belongs to the cytidylate kinase family. Type 1 subfamily
HHOFPIHL_01211 8e-26 M Lysin motif
HHOFPIHL_01212 3.7e-252 recQ1 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHOFPIHL_01213 4.1e-184 ypbB 5.1.3.1 S Helix-turn-helix domain
HHOFPIHL_01214 6.5e-94 U Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
HHOFPIHL_01215 2.7e-129 rluB 5.4.99.19, 5.4.99.21, 5.4.99.22 J Belongs to the pseudouridine synthase RsuA family
HHOFPIHL_01216 3e-102 scpB D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HHOFPIHL_01217 7.4e-133 scpA D Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HHOFPIHL_01218 3.1e-71 ribT K COG0454 Histone acetyltransferase HPA2 and related acetyltransferases
HHOFPIHL_01219 9.8e-166 xerD D recombinase XerD
HHOFPIHL_01220 9.3e-169 cvfB S S1 domain
HHOFPIHL_01221 0.0 pyk 2.7.1.40, 2.7.7.4 G Belongs to the pyruvate kinase family
HHOFPIHL_01222 7.3e-127 tal 2.2.1.2 H Transaldolase/Fructose-6-phosphate aldolase
HHOFPIHL_01223 0.0 dnaE 2.7.7.7 L DNA polymerase
HHOFPIHL_01224 0.0 clpB O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHOFPIHL_01225 2.5e-236 pepT 3.4.11.4 E Cleaves the N-terminal amino acid of tripeptides
HHOFPIHL_01226 3.1e-155 yqfO 3.5.4.16 S Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HHOFPIHL_01227 2.3e-125 trmK 2.1.1.217 S SAM-dependent methyltransferase
HHOFPIHL_01228 0.0 ydgH S MMPL family
HHOFPIHL_01229 1.6e-88 K Transcriptional regulator
HHOFPIHL_01230 4.6e-197 sigA K Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
HHOFPIHL_01231 0.0 dnaG L RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
HHOFPIHL_01232 0.0 glyS 6.1.1.14 J Glycyl-tRNA synthetase beta subunit
HHOFPIHL_01233 1.5e-177 glyQ 6.1.1.14 J glycyl-tRNA synthetase alpha subunit
HHOFPIHL_01234 3.3e-149 recO L Involved in DNA repair and RecF pathway recombination
HHOFPIHL_01235 1.5e-169 era S An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HHOFPIHL_01236 3.4e-62 dgkA 2.7.1.107, 2.7.1.66 M Diacylglycerol kinase
HHOFPIHL_01237 8.5e-79 ybeY 2.6.99.2, 3.5.4.5 S Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HHOFPIHL_01238 7.7e-180 phoH T phosphate starvation-inducible protein PhoH
HHOFPIHL_01239 7e-72 yqeY S YqeY-like protein
HHOFPIHL_01240 3.4e-67 hxlR K Transcriptional regulator, HxlR family
HHOFPIHL_01241 5.7e-194 qor 1.1.1.1, 1.6.5.5 C Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily
HHOFPIHL_01242 1.3e-22 rpsU J Belongs to the bacterial ribosomal protein bS21 family
HHOFPIHL_01243 1.4e-150 yqfL 2.7.11.33, 2.7.4.28 F Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
HHOFPIHL_01244 2.9e-173 nfo 3.1.21.2 L Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HHOFPIHL_01245 1.8e-242 tagF1 2.7.8.12, 2.7.8.45 M glycerophosphotransferase
HHOFPIHL_01246 8e-151 tagG U Transport permease protein
HHOFPIHL_01247 1.5e-190 tagB 2.7.8.14, 2.7.8.44, 2.7.8.47 M CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase
HHOFPIHL_01248 1.7e-162 yitT S Uncharacterised 5xTM membrane BCR, YitT family COG1284
HHOFPIHL_01249 2.8e-96 msrA 1.8.4.11, 1.8.4.12 O Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HHOFPIHL_01250 0.0 aspS 6.1.1.12 J Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp)
HHOFPIHL_01251 8.7e-248 hisS 6.1.1.21 J histidyl-tRNA synthetase
HHOFPIHL_01252 6.1e-99
HHOFPIHL_01253 5.8e-160 lytH 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHOFPIHL_01254 3.5e-165 yniA G Fructosamine kinase
HHOFPIHL_01255 5.1e-116 3.1.3.18 S HAD-hyrolase-like
HHOFPIHL_01256 1.1e-75 dtd J rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality
HHOFPIHL_01257 0.0 relA 2.7.6.5 KT In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HHOFPIHL_01258 2.7e-60
HHOFPIHL_01259 3.4e-135 rsmE 2.1.1.193 J Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit
HHOFPIHL_01260 9.7e-180 prmA J Ribosomal protein L11 methyltransferase
HHOFPIHL_01261 6.1e-54
HHOFPIHL_01262 9.1e-28 mscL M Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
HHOFPIHL_01263 1.8e-62
HHOFPIHL_01265 3.3e-42
HHOFPIHL_01267 4.8e-213 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHOFPIHL_01269 1.8e-189 L Helix-turn-helix domain
HHOFPIHL_01270 4e-08
HHOFPIHL_01272 2.7e-185 L PFAM Integrase, catalytic core
HHOFPIHL_01273 1e-53 asp2 S Asp23 family, cell envelope-related function
HHOFPIHL_01274 9.2e-66 asp S Asp23 family, cell envelope-related function
HHOFPIHL_01275 2.5e-23
HHOFPIHL_01276 2.5e-71
HHOFPIHL_01277 3.7e-25 S Transglycosylase associated protein
HHOFPIHL_01278 5.3e-179 M Glycosyl hydrolases family 25
HHOFPIHL_01280 4.3e-60 S Bacteriophage holin family
HHOFPIHL_01281 2.2e-21
HHOFPIHL_01283 2.4e-35
HHOFPIHL_01284 8.8e-70
HHOFPIHL_01285 3.4e-36
HHOFPIHL_01286 6.6e-74 Z012_12235 S Baseplate J-like protein
HHOFPIHL_01287 4.6e-11
HHOFPIHL_01288 8.9e-13
HHOFPIHL_01289 4e-64
HHOFPIHL_01290 3.4e-16
HHOFPIHL_01291 2.4e-24 M LysM domain
HHOFPIHL_01292 3.1e-284 M Phage tail tape measure protein TP901
HHOFPIHL_01295 5.6e-23
HHOFPIHL_01296 7.6e-46 S Protein of unknown function (DUF3383)
HHOFPIHL_01297 9.9e-11
HHOFPIHL_01298 5.3e-07
HHOFPIHL_01299 2.7e-29
HHOFPIHL_01302 8.9e-15 N PFAM Bacterial Ig-like domain (group 2)
HHOFPIHL_01303 1.5e-28 S Phage major capsid protein E
HHOFPIHL_01304 6.3e-13
HHOFPIHL_01306 1.3e-11 K cell adhesion
HHOFPIHL_01307 4.1e-53 S Phage portal protein, SPP1 Gp6-like
HHOFPIHL_01308 6.8e-135 S Terminase-like family
HHOFPIHL_01309 3.1e-33 S Phage terminase small subunit
HHOFPIHL_01316 7.9e-41 S Beta protein
HHOFPIHL_01317 1.4e-43 S Psort location Cytoplasmic, score
HHOFPIHL_01319 5.4e-43 arpU S Phage transcriptional regulator, ArpU family
HHOFPIHL_01322 3.8e-62 S Endodeoxyribonuclease RusA
HHOFPIHL_01323 3.3e-55 K AntA/AntB antirepressor
HHOFPIHL_01324 6.9e-37 L Domain of unknown function (DUF4373)
HHOFPIHL_01325 2.9e-78 pi112 3.6.4.12 L PDDEXK-like domain of unknown function (DUF3799)
HHOFPIHL_01326 9.4e-67 recT L RecT family
HHOFPIHL_01330 2.7e-07
HHOFPIHL_01336 1e-36 yvaO K Helix-turn-helix XRE-family like proteins
HHOFPIHL_01337 9.6e-46 E IrrE N-terminal-like domain
HHOFPIHL_01339 4.9e-30
HHOFPIHL_01340 1.3e-15
HHOFPIHL_01341 3.2e-17
HHOFPIHL_01343 7.6e-25
HHOFPIHL_01344 4.1e-54
HHOFPIHL_01346 5.7e-135 3.6.4.12 L Belongs to the 'phage' integrase family
HHOFPIHL_01347 0.0 lepA M Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
HHOFPIHL_01348 1.4e-250 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHOFPIHL_01349 5.2e-34 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOFPIHL_01350 3.8e-237 dltB M MBOAT, membrane-bound O-acyltransferase family
HHOFPIHL_01351 1.3e-298 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOFPIHL_01352 1.7e-17 dltX S D-Ala-teichoic acid biosynthesis protein
HHOFPIHL_01353 1.8e-189 L Helix-turn-helix domain
HHOFPIHL_01354 1.3e-178 dnaJ O ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
HHOFPIHL_01355 0.0 dnaK O Heat shock 70 kDa protein
HHOFPIHL_01356 1.8e-83 grpE O Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HHOFPIHL_01357 7.8e-191 hrcA K Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons
HHOFPIHL_01358 4.3e-180 ribF 2.7.1.26, 2.7.7.2 H Belongs to the ribF family
HHOFPIHL_01359 6.7e-170 truB 5.4.99.25 J Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HHOFPIHL_01360 9.4e-56 rbfA J One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HHOFPIHL_01361 0.0 infB J One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HHOFPIHL_01362 1.4e-44 ylxQ J ribosomal protein
HHOFPIHL_01363 2.3e-47 ylxR K Protein of unknown function (DUF448)
HHOFPIHL_01364 1.2e-190 nusA K Participates in both transcription termination and antitermination
HHOFPIHL_01365 1.8e-81 rimP J Required for maturation of 30S ribosomal subunits
HHOFPIHL_01366 1.4e-38
HHOFPIHL_01367 0.0 polC 2.7.7.7 L Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HHOFPIHL_01368 0.0 proS 6.1.1.15 J Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
HHOFPIHL_01369 5.9e-233 rseP 3.4.21.107, 3.4.21.116 M zinc metalloprotease
HHOFPIHL_01370 2e-138 cdsA 2.7.7.41 I Belongs to the CDS family
HHOFPIHL_01371 2.1e-148 uppS 2.5.1.31 H Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HHOFPIHL_01372 3.2e-74
HHOFPIHL_01373 2.4e-85 frr J Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
HHOFPIHL_01374 1.7e-128 pyrH 2.7.4.22 F Catalyzes the reversible phosphorylation of UMP to UDP
HHOFPIHL_01375 1.9e-153 tsf J Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HHOFPIHL_01376 2.5e-139 rpsB J Belongs to the universal ribosomal protein uS2 family
HHOFPIHL_01377 3.2e-135 S Haloacid dehalogenase-like hydrolase
HHOFPIHL_01378 4.7e-185 ldhA 1.1.1.28 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOFPIHL_01379 3.4e-45 yazA L GIY-YIG catalytic domain protein
HHOFPIHL_01380 2.1e-137 yabB 2.1.1.223 L Methyltransferase small domain
HHOFPIHL_01381 4e-121 plsC 2.3.1.51 I Acyltransferase
HHOFPIHL_01382 0.0 mdlB V ABC transporter
HHOFPIHL_01383 9.9e-287 mdlA V ABC transporter
HHOFPIHL_01384 1.6e-32 yneF S Uncharacterised protein family (UPF0154)
HHOFPIHL_01385 1.8e-37 ynzC S UPF0291 protein
HHOFPIHL_01386 3.1e-110 lexA 3.4.21.88 K Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HHOFPIHL_01387 4.2e-77 F nucleoside 2-deoxyribosyltransferase
HHOFPIHL_01388 1.8e-189 L Helix-turn-helix domain
HHOFPIHL_01389 6.5e-218 mvaS 2.3.3.10 I Hydroxymethylglutaryl-CoA synthase
HHOFPIHL_01390 8.2e-165 S Polyphosphate nucleotide phosphotransferase, PPK2 family
HHOFPIHL_01391 5.3e-124 G phosphoglycerate mutase
HHOFPIHL_01392 7.7e-25 KT PspC domain
HHOFPIHL_01393 4.6e-82 ndk 2.7.4.6 F Belongs to the NDK family
HHOFPIHL_01395 1.4e-175 L Integrase core domain
HHOFPIHL_01398 1.3e-69 S MTH538 TIR-like domain (DUF1863)
HHOFPIHL_01399 2.2e-165 yegS 2.7.1.107 I Diacylglycerol kinase catalytic domain
HHOFPIHL_01400 1.3e-74
HHOFPIHL_01402 1.1e-77 T Universal stress protein family
HHOFPIHL_01403 1.6e-91 apt 2.4.2.22, 2.4.2.7 F Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HHOFPIHL_01404 0.0 recJ L Single-stranded-DNA-specific exonuclease RecJ
HHOFPIHL_01405 4e-55 yrvD S Pfam:DUF1049
HHOFPIHL_01406 5.7e-180 rnz 3.1.26.11 J Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA
HHOFPIHL_01407 3.8e-28
HHOFPIHL_01408 6.2e-105
HHOFPIHL_01409 1.6e-246 obg S An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HHOFPIHL_01410 0.0 uvrC L The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
HHOFPIHL_01411 1.1e-15
HHOFPIHL_01412 3.2e-52 MA20_27270 S mazG nucleotide pyrophosphohydrolase
HHOFPIHL_01413 6.6e-110 engB D Necessary for normal cell division and for the maintenance of normal septation
HHOFPIHL_01414 6.9e-234 clpX O ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HHOFPIHL_01415 2.2e-222 tig D Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
HHOFPIHL_01416 1.9e-225 tuf J This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HHOFPIHL_01417 3.2e-167 S Tetratricopeptide repeat
HHOFPIHL_01418 0.0 rnjB J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOFPIHL_01419 1.3e-41 rpsO J Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HHOFPIHL_01420 2.1e-33 rpsT J Binds directly to 16S ribosomal RNA
HHOFPIHL_01421 1.4e-184 holA 2.7.7.7 L DNA polymerase III delta subunit
HHOFPIHL_01422 0.0 comEC S Competence protein ComEC
HHOFPIHL_01423 8.8e-89 comEB 3.5.4.12 F ComE operon protein 2
HHOFPIHL_01424 9.7e-121 comEA L Competence protein ComEA
HHOFPIHL_01425 4e-195 ylbL T Belongs to the peptidase S16 family
HHOFPIHL_01426 4.8e-82 coaD 2.7.7.3 H Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HHOFPIHL_01427 1.6e-97 rsmD 2.1.1.171 L RNA methyltransferase, RsmD family
HHOFPIHL_01428 1.3e-42 ylbG S Uncharacterized protein conserved in bacteria (DUF2129)
HHOFPIHL_01429 1.2e-208 ftsW D Belongs to the SEDS family
HHOFPIHL_01430 0.0 typA T GTP-binding protein TypA
HHOFPIHL_01431 1.6e-143 suhB 3.1.3.25 G Belongs to the inositol monophosphatase superfamily
HHOFPIHL_01432 7.9e-45 yktA S Belongs to the UPF0223 family
HHOFPIHL_01433 7.1e-164 1.1.1.27 C L-malate dehydrogenase activity
HHOFPIHL_01434 2e-269 lpdA 1.8.1.4 C Dehydrogenase
HHOFPIHL_01435 5.4e-205 pdhC 2.3.1.12 C Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
HHOFPIHL_01436 2.8e-182 pdhB 1.2.4.1 C Transketolase, C-terminal domain protein
HHOFPIHL_01437 7e-214 pdhA 1.2.4.1, 1.2.4.4 C Dehydrogenase E1 component
HHOFPIHL_01438 2.8e-102 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
HHOFPIHL_01439 0.0 L Transposase
HHOFPIHL_01440 3.1e-68
HHOFPIHL_01441 1.2e-32 ykzG S Belongs to the UPF0356 family
HHOFPIHL_01442 0.0 rnjA J An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HHOFPIHL_01443 5.7e-188 ytlR 2.7.1.91 I Diacylglycerol kinase catalytic
HHOFPIHL_01444 1.3e-28
HHOFPIHL_01445 6.1e-110 mltD CBM50 M NlpC P60 family protein
HHOFPIHL_01446 9.7e-165 ypuA S Protein of unknown function (DUF1002)
HHOFPIHL_01447 1.6e-168 ykfC 3.4.14.13 M NlpC/P60 family
HHOFPIHL_01448 0.0 tkt 2.2.1.1 H Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HHOFPIHL_01449 2.8e-160 rbsK 2.7.1.15 H Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HHOFPIHL_01450 3.6e-185 rbsR K helix_turn _helix lactose operon repressor
HHOFPIHL_01451 1.1e-189 yghZ C Aldo keto reductase family protein
HHOFPIHL_01452 9e-159 murQ 4.2.1.126 G Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HHOFPIHL_01453 1.5e-308 E ABC transporter, substratebinding protein
HHOFPIHL_01454 3.4e-280 nylA 3.5.1.4 J Belongs to the amidase family
HHOFPIHL_01455 1.8e-159 yckB ET Belongs to the bacterial solute-binding protein 3 family
HHOFPIHL_01456 2.5e-121 yecS E ABC transporter permease
HHOFPIHL_01457 1.2e-126 yoaK S Protein of unknown function (DUF1275)
HHOFPIHL_01458 1.4e-176 prs 2.7.6.1 F Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HHOFPIHL_01459 0.0 recD2 3.1.11.5 L DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity
HHOFPIHL_01460 3.4e-118 S Repeat protein
HHOFPIHL_01461 1e-119 pgm6 5.4.2.11, 5.4.2.12 G phosphoglycerate mutase
HHOFPIHL_01462 8e-224 mnmA 2.8.1.13 J Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34
HHOFPIHL_01464 1.5e-58 XK27_04120 S Putative amino acid metabolism
HHOFPIHL_01465 8.9e-223 iscS 2.8.1.7 E Aminotransferase class V
HHOFPIHL_01466 2.5e-124 mtnN 3.2.2.9 E Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HHOFPIHL_01467 5.2e-31
HHOFPIHL_01468 2.5e-95 nudF 3.6.1.13 L ADP-ribose pyrophosphatase
HHOFPIHL_01469 2.2e-34 cspA K Cold shock protein
HHOFPIHL_01470 0.0 ileS 6.1.1.5 J amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HHOFPIHL_01471 3.3e-92 divIVA D DivIVA domain protein
HHOFPIHL_01472 4.4e-146 ylmH S S4 domain protein
HHOFPIHL_01473 4.1e-41 yggT S YGGT family
HHOFPIHL_01474 1.7e-75 sepF D Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA
HHOFPIHL_01475 1.1e-215 ftsZ D Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HHOFPIHL_01476 2e-244 ftsA D Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring
HHOFPIHL_01477 1.8e-148 divIB D Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex
HHOFPIHL_01478 4.4e-200 murG 2.4.1.227, 6.3.2.8 GT28 M Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HHOFPIHL_01479 1.1e-251 murD 6.3.2.9 M Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HHOFPIHL_01480 1.9e-183 mraY 2.7.8.13 M First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HHOFPIHL_01481 0.0 ftsI 3.4.16.4 M Penicillin-binding Protein
HHOFPIHL_01482 7.6e-62 ftsL D Cell division protein FtsL
HHOFPIHL_01483 1.7e-176 rsmH 2.1.1.199 J Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA
HHOFPIHL_01484 2e-79 mraZ K Belongs to the MraZ family
HHOFPIHL_01485 7.5e-61 S Protein of unknown function (DUF3397)
HHOFPIHL_01486 2.2e-12 S Protein of unknown function (DUF4044)
HHOFPIHL_01487 0.0 ftsK D Belongs to the FtsK SpoIIIE SftA family
HHOFPIHL_01488 2.7e-96 trmL 2.1.1.207 J Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily
HHOFPIHL_01489 4.8e-162 rrmA 2.1.1.187 H Methyltransferase
HHOFPIHL_01490 1.6e-203 XK27_05220 S AI-2E family transporter
HHOFPIHL_01491 3.9e-108 cutC P Participates in the control of copper homeostasis
HHOFPIHL_01492 5.5e-16 tagE1 2.4.1.52 GT4 M Glycosyl transferases group 1
HHOFPIHL_01493 2.1e-269 tagE3 2.4.1.52 GT4 M Glycosyl transferases group 1
HHOFPIHL_01494 5.6e-270 tagE2 2.4.1.52 GT4 M Glycosyl transferases group 1
HHOFPIHL_01495 1.9e-27
HHOFPIHL_01496 1.3e-63 S Pfam Methyltransferase
HHOFPIHL_01497 8.4e-60 alr 5.1.1.1, 6.3.2.10 M UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HHOFPIHL_01498 3.1e-28 3.1.3.18 S Pfam Methyltransferase
HHOFPIHL_01499 3.7e-47 3.1.3.18 S Pfam Methyltransferase
HHOFPIHL_01500 7.5e-174 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 G Responsible for synthesis of pseudouridine from uracil
HHOFPIHL_01501 2e-149 nadK 2.7.1.23 F Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HHOFPIHL_01502 3.3e-118 yjbM 2.7.6.5 S RelA SpoT domain protein
HHOFPIHL_01503 1.4e-113 yjbH Q Thioredoxin
HHOFPIHL_01504 2.5e-158 degV S DegV family
HHOFPIHL_01505 0.0 pepF E oligoendopeptidase F
HHOFPIHL_01506 5.1e-201 coiA 3.6.4.12 S Competence protein
HHOFPIHL_01507 3.6e-125 trmB 2.1.1.297, 2.1.1.33 J Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA
HHOFPIHL_01508 1.9e-149 ytmP 2.7.1.89 M Choline/ethanolamine kinase
HHOFPIHL_01509 5.9e-222 ecsB U ABC transporter
HHOFPIHL_01510 3e-135 ecsA V ABC transporter, ATP-binding protein
HHOFPIHL_01511 3.1e-83 hit FG histidine triad
HHOFPIHL_01512 1.9e-50
HHOFPIHL_01513 9.1e-151 prsA 5.2.1.8 M Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins
HHOFPIHL_01514 1.9e-183 S Metal dependent phosphohydrolases with conserved 'HD' motif.
HHOFPIHL_01515 0.0 L AAA domain
HHOFPIHL_01516 9.6e-233 yhaO L Ser Thr phosphatase family protein
HHOFPIHL_01517 1.3e-52 yheA S Belongs to the UPF0342 family
HHOFPIHL_01518 0.0 pbp2A 2.4.1.129, 3.4.16.4 GT51 M penicillin-binding protein
HHOFPIHL_01519 4.7e-79 argR K Regulates arginine biosynthesis genes
HHOFPIHL_01520 0.0 argS 6.1.1.19 J Arginyl-tRNA synthetase
HHOFPIHL_01522 1.4e-17
HHOFPIHL_01523 1.1e-231 3.2.1.96, 3.5.1.28 M N-acetylmuramoyl-L-alanine amidase
HHOFPIHL_01524 4e-98 1.5.1.3 H RibD C-terminal domain
HHOFPIHL_01525 8.6e-54 S Protein of unknown function (DUF1516)
HHOFPIHL_01526 1.6e-131 racD 5.1.1.13 M Belongs to the aspartate glutamate racemases family
HHOFPIHL_01527 2.3e-253 yxbA 6.3.1.12 S ATP-grasp enzyme
HHOFPIHL_01528 0.0 asnB 6.3.5.4 E Asparagine synthase
HHOFPIHL_01529 4.9e-120 ntcA2 4.1.99.16, 4.2.3.22, 4.2.3.75 K Transcriptional regulator, Crp Fnr family
HHOFPIHL_01530 3.1e-275 pipD E Peptidase family C69
HHOFPIHL_01531 1.3e-37
HHOFPIHL_01532 0.0
HHOFPIHL_01533 9.1e-175 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_01536 0.0 uvrA3 L ABC transporter
HHOFPIHL_01537 1.9e-126 L Helix-turn-helix domain
HHOFPIHL_01539 5.1e-47
HHOFPIHL_01540 1.2e-83 V VanZ like family
HHOFPIHL_01541 9.4e-83 ohrR K Transcriptional regulator
HHOFPIHL_01542 2.3e-122 S CAAX protease self-immunity
HHOFPIHL_01543 1.1e-37
HHOFPIHL_01544 4.6e-177 1.1.1.26 CH Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HHOFPIHL_01545 0.0 trePP 2.4.1.216, 2.4.1.8, 3.1.3.12, 3.2.1.28 GH37,GH65 G Glycosyl hydrolase family 65 central catalytic domain
HHOFPIHL_01546 1e-119 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S beta-phosphoglucomutase
HHOFPIHL_01547 1.2e-143 S haloacid dehalogenase-like hydrolase
HHOFPIHL_01548 4.5e-120 dck 2.7.1.74 F Deoxynucleoside kinase
HHOFPIHL_01549 1.8e-56 XK27_08430 S Staphylococcal protein of unknown function (DUF960)
HHOFPIHL_01550 3.9e-260 bmr3 EGP Major facilitator Superfamily
HHOFPIHL_01551 9.8e-214 metK 2.5.1.6 H Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HHOFPIHL_01552 1.5e-121
HHOFPIHL_01553 5.3e-62
HHOFPIHL_01554 4.7e-105
HHOFPIHL_01555 2.6e-52 ybjQ S Belongs to the UPF0145 family
HHOFPIHL_01556 3.6e-91 zmp2 O Zinc-dependent metalloprotease
HHOFPIHL_01571 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHOFPIHL_01572 1.6e-35 ykuJ S Protein of unknown function (DUF1797)
HHOFPIHL_01573 1.9e-184 mprF S Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HHOFPIHL_01574 3.6e-196 cpoA GT4 M Glycosyltransferase, group 1 family protein
HHOFPIHL_01575 2.7e-224 mgs 2.4.1.337 GT4 M Glycosyltransferase, group 1 family protein
HHOFPIHL_01576 0.0 ptsI 2.7.3.9 G General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HHOFPIHL_01577 7.2e-40 ptsH G phosphocarrier protein HPR
HHOFPIHL_01578 3.9e-30
HHOFPIHL_01579 0.0 clpE O Belongs to the ClpA ClpB family
HHOFPIHL_01580 1.1e-214 manA 1.14.13.81, 5.3.1.8, 5.4.2.8 G MucBP domain
HHOFPIHL_01581 0.0 pacL3 3.6.3.8 P Cation transporter/ATPase, N-terminus
HHOFPIHL_01582 9.2e-283 pipD E Dipeptidase
HHOFPIHL_01583 9.6e-258 nox 1.6.3.4 C NADH oxidase
HHOFPIHL_01584 9.1e-279 XK27_00720 S Leucine-rich repeat (LRR) protein
HHOFPIHL_01585 1.3e-306 prfC J Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HHOFPIHL_01586 3.1e-90
HHOFPIHL_01587 0.0 2.7.8.12 M glycerophosphotransferase
HHOFPIHL_01588 3.7e-157
HHOFPIHL_01589 2.6e-76 tagD 2.7.7.15, 2.7.7.39 IM Glycerol-3-phosphate cytidylyltransferase
HHOFPIHL_01590 1.5e-179 yueF S AI-2E family transporter
HHOFPIHL_01591 4.4e-108 ygaC J Belongs to the UPF0374 family
HHOFPIHL_01592 5.6e-39 S Bacteriocin-protection, YdeI or OmpD-Associated
HHOFPIHL_01593 2.3e-215 pbpX2 V Beta-lactamase
HHOFPIHL_01594 1.2e-143 recX 2.4.1.337 GT4 S Regulatory protein RecX
HHOFPIHL_01595 1e-78 fld C Flavodoxin
HHOFPIHL_01596 9e-159 yihY S Belongs to the UPF0761 family
HHOFPIHL_01597 2.1e-157 S Nuclease-related domain
HHOFPIHL_01598 1.8e-212 mnaA 5.1.3.14 G Belongs to the UDP-N-acetylglucosamine 2-epimerase family
HHOFPIHL_01599 2.5e-159 csbB 2.4.1.83 GT2 M Glycosyltransferase like family 2
HHOFPIHL_01600 4.1e-232 gntP EG Gluconate
HHOFPIHL_01601 5.6e-77 T Universal stress protein family
HHOFPIHL_01603 3.5e-212 yfmL 3.6.4.13 L DEAD DEAH box helicase
HHOFPIHL_01604 2.5e-186 mocA S Oxidoreductase
HHOFPIHL_01605 5.7e-64 S Domain of unknown function (DUF4828)
HHOFPIHL_01606 8.7e-147 lys M Glycosyl hydrolases family 25
HHOFPIHL_01607 3.2e-150 gntR K rpiR family
HHOFPIHL_01608 2.1e-304 gntK 2.7.1.12, 2.7.1.16, 2.7.1.17 G Belongs to the FGGY kinase family
HHOFPIHL_01609 4.3e-213 gntP EG Gluconate
HHOFPIHL_01610 2.8e-233 potE E amino acid
HHOFPIHL_01611 4.3e-250 fucP G Major Facilitator Superfamily
HHOFPIHL_01612 2.5e-65 rbsD 5.4.99.62 G Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose
HHOFPIHL_01613 2.4e-297 gshF 6.3.2.2 H Belongs to the glutamate--cysteine ligase type 1 family
HHOFPIHL_01614 8.7e-240 pdp 2.4.2.2, 2.4.2.4 F pyrimidine-nucleoside phosphorylase
HHOFPIHL_01615 5.2e-173 deoR K sugar-binding domain protein
HHOFPIHL_01616 1.7e-128 deoD 2.4.2.1, 2.4.2.28 F Purine nucleoside phosphorylase
HHOFPIHL_01617 3.8e-234 deoB 5.4.2.7 G Phosphotransfer between the C1 and C5 carbon atoms of pentose
HHOFPIHL_01618 1.3e-120 deoC 4.1.2.4, 5.4.2.8 F Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HHOFPIHL_01619 3.4e-28 cro K Helix-turn-helix XRE-family like proteins
HHOFPIHL_01620 4.6e-58 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_01621 1.3e-145 3.1.3.48 T Pfam:Y_phosphatase3C
HHOFPIHL_01622 1.8e-195 C Oxidoreductase
HHOFPIHL_01623 7.8e-55 pduU E BMC
HHOFPIHL_01624 4.1e-220 ackA 2.7.2.1, 2.7.2.15 F Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HHOFPIHL_01625 6.2e-210 pduQ C Iron-containing alcohol dehydrogenase
HHOFPIHL_01626 3e-265 pduP 1.2.1.87 C Aldehyde dehydrogenase family
HHOFPIHL_01627 1.4e-81 pduO S Haem-degrading
HHOFPIHL_01628 5.8e-103 pduO 2.5.1.17 S Cobalamin adenosyltransferase
HHOFPIHL_01629 6e-42 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HHOFPIHL_01630 3e-90 S Putative propanediol utilisation
HHOFPIHL_01631 6.1e-114 pduL 2.3.1.222, 2.3.1.8 Q Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate
HHOFPIHL_01632 4.9e-42 pduA_4 CQ BMC
HHOFPIHL_01633 9.7e-83 pduK CQ BMC
HHOFPIHL_01634 1.1e-56 pduH S Dehydratase medium subunit
HHOFPIHL_01635 0.0 pduG D Diol dehydratase reactivase ATPase-like domain
HHOFPIHL_01636 3e-90 pduE 4.2.1.28 Q Dehydratase small subunit
HHOFPIHL_01637 2e-129 pduD 4.2.1.28, 4.2.1.30 Q Dehydratase medium subunit
HHOFPIHL_01638 0.0 pduC 4.2.1.28 Q Dehydratase large subunit
HHOFPIHL_01639 4.1e-130 pduB E BMC
HHOFPIHL_01640 5.2e-41 pduA_4 CQ BMC
HHOFPIHL_01641 3.7e-207 K helix_turn_helix, arabinose operon control protein
HHOFPIHL_01642 9.5e-132 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHOFPIHL_01643 3.3e-42 eutP E Ethanolamine utilisation - propanediol utilisation
HHOFPIHL_01644 8.3e-257 rumA 2.1.1.190 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOFPIHL_01645 9.4e-189 yegS 2.7.1.107 G Lipid kinase
HHOFPIHL_01646 6.5e-273 gatB 6.1.1.12, 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOFPIHL_01647 3.8e-276 gatA 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
HHOFPIHL_01648 1.5e-49 gatC 6.3.5.6, 6.3.5.7 J Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HHOFPIHL_01649 1.1e-193 camS S sex pheromone
HHOFPIHL_01650 0.0 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHOFPIHL_01651 0.0 pcrA 3.6.4.12 L ATP-dependent DNA helicase
HHOFPIHL_01652 3.2e-214 purK2 6.3.4.18 F Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HHOFPIHL_01653 5.1e-99 xpt 2.4.2.22, 2.4.2.7 F Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis
HHOFPIHL_01654 3.1e-72 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HHOFPIHL_01655 7.3e-64 menA 2.5.1.74 H 1,4-dihydroxy-2-naphthoate
HHOFPIHL_01656 1.2e-180 hepT 2.5.1.30, 2.5.1.90 H Belongs to the FPP GGPP synthase family
HHOFPIHL_01657 0.0 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HHOFPIHL_01658 1.1e-269 cydD CO ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydD
HHOFPIHL_01659 1.1e-173 cydB 1.10.3.14 C Cytochrome d ubiquinol oxidase subunit II
HHOFPIHL_01660 3.5e-282 cydA 1.10.3.14 C ubiquinol oxidase
HHOFPIHL_01661 8.7e-181 pdxB EH D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain
HHOFPIHL_01662 1.7e-145 rfbB 4.2.1.46 M Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily
HHOFPIHL_01663 3.3e-144 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHOFPIHL_01664 7.4e-176 cps1C S Membrane protein involved in the export of O-antigen and teichoic acid
HHOFPIHL_01665 1.9e-179 glf 5.4.99.9 M UDP-galactopyranose mutase
HHOFPIHL_01666 7.5e-28
HHOFPIHL_01667 7.7e-73 glfT1 1.1.1.133 S Glycosyltransferase like family 2
HHOFPIHL_01668 1.1e-172 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_01669 8e-159 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHOFPIHL_01670 6.5e-190 lplA2 6.3.1.20 H Bacterial lipoate protein ligase C-terminus
HHOFPIHL_01671 1.4e-254 yfnA E Amino Acid
HHOFPIHL_01672 3e-195 asnA 6.3.1.1 F aspartate--ammonia ligase
HHOFPIHL_01673 1.3e-79 ribH 2.5.1.78 H Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
HHOFPIHL_01674 6.8e-223 ribBA 3.5.4.25, 4.1.99.12 H Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate
HHOFPIHL_01675 1.1e-104 ribE 2.5.1.9, 3.5.4.25, 4.1.99.12 H Riboflavin synthase
HHOFPIHL_01676 8e-199 ribD 1.1.1.193, 3.5.4.26 H Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HHOFPIHL_01677 1.8e-116 ktrA P domain protein
HHOFPIHL_01678 1.4e-240 ktrB P Potassium uptake protein
HHOFPIHL_01679 1.9e-194 manA 5.3.1.8 G mannose-6-phosphate isomerase
HHOFPIHL_01680 4.7e-64 rpsI J Belongs to the universal ribosomal protein uS9 family
HHOFPIHL_01681 1.3e-78 rplM J This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HHOFPIHL_01682 5e-153 truA 5.4.99.12 J Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs
HHOFPIHL_01683 1.4e-157 ecfA2 3.6.3.55 P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOFPIHL_01684 4.9e-151 cbiO P ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HHOFPIHL_01685 7.4e-62 rplQ J Ribosomal protein L17
HHOFPIHL_01686 2.8e-171 rpoA 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOFPIHL_01687 7.5e-62 rpsK J Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HHOFPIHL_01688 1.3e-60 rpsM J Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HHOFPIHL_01689 1.4e-33 infA J One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HHOFPIHL_01690 3.4e-123 adk 2.7.4.3 F Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
HHOFPIHL_01691 1.2e-233 secY U The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
HHOFPIHL_01692 1.9e-69 rplO J Binds to the 23S rRNA
HHOFPIHL_01693 3.8e-24 rpmD J Ribosomal protein L30
HHOFPIHL_01694 2.4e-84 rpsE J Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HHOFPIHL_01695 6.6e-57 rplR J This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HHOFPIHL_01696 3e-93 rplF J This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HHOFPIHL_01697 1e-66 rpsH J One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HHOFPIHL_01698 2.1e-94 rplE J This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HHOFPIHL_01699 1.8e-50 rplX J One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HHOFPIHL_01700 4.3e-59 rplN J Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HHOFPIHL_01701 1.9e-40 rpsQ J One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HHOFPIHL_01702 4.8e-25 rpmC J Belongs to the universal ribosomal protein uL29 family
HHOFPIHL_01703 7.8e-76 rplP J Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HHOFPIHL_01704 5.1e-119 rpsC J Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HHOFPIHL_01705 2.4e-54 rplV J The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HHOFPIHL_01706 1.8e-46 rpsS J Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HHOFPIHL_01707 6e-149 rplB J One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HHOFPIHL_01708 2e-43 rplW J One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
HHOFPIHL_01709 3.2e-107 rplD J Forms part of the polypeptide exit tunnel
HHOFPIHL_01710 6.1e-117 rplC J One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HHOFPIHL_01711 8.9e-50 rpsJ J Involved in the binding of tRNA to the ribosomes
HHOFPIHL_01712 2.7e-236 mepA V MATE efflux family protein
HHOFPIHL_01713 0.0 fusA J Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HHOFPIHL_01714 6.4e-84 rpsG J One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
HHOFPIHL_01715 1.2e-70 rpsL J Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HHOFPIHL_01716 1.4e-110 pilD 3.4.23.43 NOU Bacterial Peptidase A24 N-terminal domain
HHOFPIHL_01717 0.0 rpoC 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOFPIHL_01718 0.0 rpoB 2.7.7.6 K DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HHOFPIHL_01719 5e-105 K Bacterial regulatory proteins, tetR family
HHOFPIHL_01720 0.0 clpC O Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
HHOFPIHL_01721 9.9e-77 ctsR K Belongs to the CtsR family
HHOFPIHL_01730 2e-212 serS 6.1.1.11 J Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HHOFPIHL_01731 9.5e-115 dak 2.7.1.74, 2.7.1.76 F deoxynucleoside kinase
HHOFPIHL_01732 4.3e-236 L Transposase
HHOFPIHL_01733 3.7e-274 lysP E amino acid
HHOFPIHL_01734 1e-24 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHOFPIHL_01735 6.9e-131 I alpha/beta hydrolase fold
HHOFPIHL_01736 1e-119 lssY 3.6.1.27 I phosphatase
HHOFPIHL_01737 1.1e-72 S Threonine/Serine exporter, ThrE
HHOFPIHL_01738 6.4e-118 thrE S Putative threonine/serine exporter
HHOFPIHL_01739 2.6e-120 sirR K iron dependent repressor
HHOFPIHL_01740 1.2e-158 czcD P cation diffusion facilitator family transporter
HHOFPIHL_01741 4.3e-103 K Acetyltransferase (GNAT) domain
HHOFPIHL_01742 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_01743 3e-45 merR K MerR HTH family regulatory protein
HHOFPIHL_01744 1.8e-268 lmrB EGP Major facilitator Superfamily
HHOFPIHL_01745 3.5e-105 S Domain of unknown function (DUF4811)
HHOFPIHL_01746 1e-37 yyaN K MerR HTH family regulatory protein
HHOFPIHL_01747 7.4e-108 azlC E branched-chain amino acid
HHOFPIHL_01748 2.8e-49 azlD S Branched-chain amino acid transport protein (AzlD)
HHOFPIHL_01749 9.5e-231 pyrP F Permease
HHOFPIHL_01750 2.1e-216 EGP Major facilitator Superfamily
HHOFPIHL_01751 2.6e-70
HHOFPIHL_01752 6e-91 paiA 2.3.1.57 K Acetyltransferase (GNAT) domain
HHOFPIHL_01753 3.8e-87 nimA S resistance protein
HHOFPIHL_01754 6.3e-105 3.2.2.20 K acetyltransferase
HHOFPIHL_01755 7.2e-141 yejC S Protein of unknown function (DUF1003)
HHOFPIHL_01756 1.1e-166 rluD 5.4.99.23, 5.4.99.28, 5.4.99.29 J Responsible for synthesis of pseudouridine from uracil
HHOFPIHL_01757 1.4e-53 S Glycine cleavage H-protein
HHOFPIHL_01760 1.5e-90 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HHOFPIHL_01761 1e-281 araA 5.3.1.4 G Catalyzes the conversion of L-arabinose to L-ribulose
HHOFPIHL_01762 3.2e-138 araD 4.1.2.17, 5.1.3.4 G links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source
HHOFPIHL_01763 1.2e-304 araB 2.7.1.12, 2.7.1.16, 2.7.1.17 G carbohydrate kinase FGGY
HHOFPIHL_01764 5.3e-204 araP U Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family
HHOFPIHL_01765 2.5e-200 araR K Transcriptional regulator
HHOFPIHL_01766 2.3e-102 maa 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HHOFPIHL_01767 1.6e-171 K transcriptional regulator, ArsR family
HHOFPIHL_01768 1.2e-201 abf G Belongs to the glycosyl hydrolase 43 family
HHOFPIHL_01769 3.4e-236 lacY G Oligosaccharide H symporter
HHOFPIHL_01770 1.5e-296 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HHOFPIHL_01771 0.0 recQ 3.6.4.12 L ATP-dependent DNA helicase RecQ
HHOFPIHL_01772 2e-68 K Transcriptional regulator
HHOFPIHL_01773 9e-96 1.5.1.40 S NADP oxidoreductase coenzyme F420-dependent
HHOFPIHL_01774 1.8e-278 pipD E Dipeptidase
HHOFPIHL_01775 9.6e-264 arcD E Arginine ornithine antiporter
HHOFPIHL_01776 0.0 pepN 3.4.11.2 E aminopeptidase
HHOFPIHL_01777 4.3e-73 S Iron-sulphur cluster biosynthesis
HHOFPIHL_01778 0.0 rafA 3.2.1.22 G alpha-galactosidase
HHOFPIHL_01779 1.1e-305 guaA 2.3.1.128, 6.3.5.2 F Catalyzes the synthesis of GMP from XMP
HHOFPIHL_01780 2.9e-102 aacA4_1 4.1.1.17 K acetyltransferase
HHOFPIHL_01781 2.4e-175 coaA 2.7.1.33 F Pantothenic acid kinase
HHOFPIHL_01782 0.0 helD 3.6.4.12 L DNA helicase
HHOFPIHL_01783 2.2e-289 yjbQ P TrkA C-terminal domain protein
HHOFPIHL_01784 5.9e-120 G phosphoglycerate mutase
HHOFPIHL_01785 1.3e-179 oppF P Belongs to the ABC transporter superfamily
HHOFPIHL_01786 3.5e-205 oppD P Belongs to the ABC transporter superfamily
HHOFPIHL_01787 9.8e-186 oppC EP ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOFPIHL_01788 2.2e-152 oppB P ABC-type dipeptide oligopeptide nickel transport systems, permease components
HHOFPIHL_01789 1e-306 oppA E ABC transporter, substratebinding protein
HHOFPIHL_01790 5.1e-306 oppA E ABC transporter, substratebinding protein
HHOFPIHL_01791 9.2e-226 hflX S GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HHOFPIHL_01792 1.6e-109 glnP P ABC transporter permease
HHOFPIHL_01793 1.1e-110 gluC P ABC transporter permease
HHOFPIHL_01794 2.4e-150 glnH ET ABC transporter substrate-binding protein
HHOFPIHL_01795 1.6e-134 glnQ 3.6.3.21 E ABC transporter, ATP-binding protein
HHOFPIHL_01796 6.6e-173
HHOFPIHL_01797 5.3e-13 3.2.1.14 GH18
HHOFPIHL_01798 4.7e-79 zur P Belongs to the Fur family
HHOFPIHL_01799 2.3e-75 gmk2 2.7.4.8 F Guanylate kinase
HHOFPIHL_01800 4.4e-76 apfA 2.7.7.72, 3.6.1.61 F Nudix hydrolase
HHOFPIHL_01801 1.2e-242 yfnA E Amino Acid
HHOFPIHL_01802 0.0 pepX 3.4.14.11 E Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline
HHOFPIHL_01803 3.9e-178 pip 3.4.11.5 E Releases the N-terminal proline from various substrates
HHOFPIHL_01804 4.6e-87 M ErfK YbiS YcfS YnhG
HHOFPIHL_01805 6.7e-295 S ABC transporter, ATP-binding protein
HHOFPIHL_01806 4e-68 E Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
HHOFPIHL_01807 6.9e-127 XK27_07075 S CAAX protease self-immunity
HHOFPIHL_01808 5.2e-122 cmpC S ATPases associated with a variety of cellular activities
HHOFPIHL_01809 7.1e-170 WQ51_06230 U Belongs to the binding-protein-dependent transport system permease family
HHOFPIHL_01810 3.9e-168 XK27_00670 S ABC transporter
HHOFPIHL_01811 9.1e-164 degV S Uncharacterised protein, DegV family COG1307
HHOFPIHL_01812 2.9e-179 XK27_08835 S ABC transporter
HHOFPIHL_01813 3e-154 XK27_08840 U Belongs to the binding-protein-dependent transport system permease family
HHOFPIHL_01814 3.3e-138 XK27_08845 S ABC transporter, ATP-binding protein
HHOFPIHL_01816 9.5e-158 glxR 1.1.1.31, 1.1.1.60 I Dehydrogenase
HHOFPIHL_01817 5.2e-128 terC P integral membrane protein, YkoY family
HHOFPIHL_01818 2e-244 pbpX1 V SH3-like domain
HHOFPIHL_01819 2e-109 NU mannosyl-glycoprotein
HHOFPIHL_01820 5.7e-183 S DUF218 domain
HHOFPIHL_01821 9.9e-188 pacA 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHOFPIHL_01822 4.5e-135 IQ reductase
HHOFPIHL_01823 1.6e-14
HHOFPIHL_01824 0.0 ydgH S MMPL family
HHOFPIHL_01825 1.3e-257 ydiC1 EGP Major facilitator Superfamily
HHOFPIHL_01826 1.6e-91 K Transcriptional regulator PadR-like family
HHOFPIHL_01827 2.7e-82 merR K MerR family regulatory protein
HHOFPIHL_01828 4.8e-63 iap CBM50 M NlpC P60 family
HHOFPIHL_01829 8.3e-78 yjcF K protein acetylation
HHOFPIHL_01830 9e-124 pgm3 G phosphoglycerate mutase family
HHOFPIHL_01831 0.0 ltaS 2.7.8.20 M Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily
HHOFPIHL_01832 1.3e-179 trxB1 1.18.1.2, 1.19.1.1 C Ferredoxin--NADP reductase
HHOFPIHL_01833 7.6e-143 S Alpha/beta hydrolase of unknown function (DUF915)
HHOFPIHL_01834 1e-190 S Protease prsW family
HHOFPIHL_01835 1.6e-177 iunH2 3.2.2.1, 3.2.2.8 F nucleoside hydrolase
HHOFPIHL_01836 1.6e-07 yvlA
HHOFPIHL_01837 6.7e-229 L Transposase
HHOFPIHL_01838 2.7e-88
HHOFPIHL_01839 2.4e-150 XK27_02985 S Sucrose-6F-phosphate phosphohydrolase
HHOFPIHL_01840 1.6e-154 S Alpha/beta hydrolase of unknown function (DUF915)
HHOFPIHL_01841 6.8e-237 G The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane
HHOFPIHL_01842 2.2e-142 S Uncharacterized protein conserved in bacteria (DUF2087)
HHOFPIHL_01843 4.1e-61 S LuxR family transcriptional regulator
HHOFPIHL_01844 7.4e-134 cat 2.3.1.28 V Chloramphenicol acetyltransferase
HHOFPIHL_01845 2.6e-219 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHOFPIHL_01846 1.9e-169 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHOFPIHL_01847 4.4e-95 S ABC transporter permease
HHOFPIHL_01848 7.7e-258 P ABC transporter
HHOFPIHL_01849 7.5e-115 P Cobalt transport protein
HHOFPIHL_01850 1.2e-120 tenA 3.5.99.2 K Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HHOFPIHL_01851 6.6e-60
HHOFPIHL_01852 1.1e-08
HHOFPIHL_01854 1.3e-30
HHOFPIHL_01855 7.1e-217
HHOFPIHL_01856 6.7e-187 ansA 3.5.1.1 EJ Asparaginase
HHOFPIHL_01857 2.9e-25
HHOFPIHL_01858 8.5e-249 pbuX F xanthine permease
HHOFPIHL_01859 7.2e-169 natA S ABC transporter, ATP-binding protein
HHOFPIHL_01860 4.7e-211 natB CP ABC-2 family transporter protein
HHOFPIHL_01862 3.9e-251 yjjP S Putative threonine/serine exporter
HHOFPIHL_01863 2e-160 degV S Uncharacterised protein, DegV family COG1307
HHOFPIHL_01864 1.3e-153 1.1.1.2, 1.1.1.307 C Aldo keto reductase
HHOFPIHL_01865 1.5e-64 S Protein of unknown function (DUF1722)
HHOFPIHL_01866 2.6e-69 yqeB S Pyrimidine dimer DNA glycosylase
HHOFPIHL_01867 3.1e-283 gadB 4.1.1.15 E Belongs to the group II decarboxylase family
HHOFPIHL_01868 1.7e-125 K Crp-like helix-turn-helix domain
HHOFPIHL_01869 9.5e-239 larA 5.1.2.1 S Domain of unknown function (DUF2088)
HHOFPIHL_01870 1.2e-132 cpmA S AIR carboxylase
HHOFPIHL_01871 1.6e-230 larC 4.99.1.12 S Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HHOFPIHL_01872 2.4e-150 larE S NAD synthase
HHOFPIHL_01873 7.7e-123 glpF U Belongs to the MIP aquaporin (TC 1.A.8) family
HHOFPIHL_01874 1.3e-179 hoxN U High-affinity nickel-transport protein
HHOFPIHL_01875 3.2e-42 aroD S Serine hydrolase (FSH1)
HHOFPIHL_01876 7.7e-34 aroD S Serine hydrolase (FSH1)
HHOFPIHL_01877 5.4e-42 GnaT 2.5.1.16 K Acetyltransferase (GNAT) domain
HHOFPIHL_01879 5.2e-209 potA 3.6.3.30, 3.6.3.31 P Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
HHOFPIHL_01880 1e-148 potB P ABC transporter permease
HHOFPIHL_01881 7e-131 potC P ABC transporter permease
HHOFPIHL_01882 9.2e-203 potD P ABC transporter
HHOFPIHL_01883 4.8e-148 pstB 3.6.3.27 P Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system
HHOFPIHL_01884 4.7e-144 pstA P Phosphate transport system permease protein PstA
HHOFPIHL_01885 1e-168 pstC P probably responsible for the translocation of the substrate across the membrane
HHOFPIHL_01886 1e-154 pstS P Phosphate
HHOFPIHL_01887 1.1e-56
HHOFPIHL_01888 2.1e-31
HHOFPIHL_01889 5.3e-43
HHOFPIHL_01890 0.0 dinG 3.1.12.1, 3.6.4.12 KL DEAD_2
HHOFPIHL_01891 1.7e-125
HHOFPIHL_01892 5.5e-180 sepS16B
HHOFPIHL_01893 9.8e-286 V ABC transporter transmembrane region
HHOFPIHL_01894 0.0 KLT Protein kinase domain
HHOFPIHL_01896 1e-198 pgl 3.1.1.31 G Lactonase, 7-bladed beta-propeller
HHOFPIHL_01897 4.8e-81 yoaA 2.3.1.128 J COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HHOFPIHL_01898 6.6e-298 E amino acid
HHOFPIHL_01899 5.4e-119 S membrane
HHOFPIHL_01900 1.1e-113 S VIT family
HHOFPIHL_01901 5.7e-91 perR P Belongs to the Fur family
HHOFPIHL_01902 7.1e-179 3.2.1.96, 3.5.1.28 GH73 M N-acetylmuramoyl-L-alanine amidase
HHOFPIHL_01904 1e-126 yibF S overlaps another CDS with the same product name
HHOFPIHL_01905 2.8e-202 yibE S overlaps another CDS with the same product name
HHOFPIHL_01907 2.8e-82 uspA T Belongs to the universal stress protein A family
HHOFPIHL_01908 3.6e-128
HHOFPIHL_01909 1.5e-86 K helix_turn_helix multiple antibiotic resistance protein
HHOFPIHL_01910 0.0 pepO 3.4.24.71 O Peptidase family M13
HHOFPIHL_01912 3.1e-172
HHOFPIHL_01913 0.0 M domain protein
HHOFPIHL_01914 1.3e-44 pepO 3.4.24.71 O Peptidase family M13
HHOFPIHL_01915 9.5e-92 yvqK 1.2.1.88, 1.5.5.2, 2.5.1.17 S cob(I)alamin adenosyltransferase
HHOFPIHL_01916 0.0 rtpR 1.1.98.6, 1.17.4.1, 1.17.4.2 F ribonucleoside-triphosphate reductase activity
HHOFPIHL_01918 0.0 L Transposase
HHOFPIHL_01919 3.3e-186 galR K Transcriptional regulator
HHOFPIHL_01920 4.5e-285 galT 2.7.7.12 G UDP-glucose--hexose-1-phosphate uridylyltransferase
HHOFPIHL_01921 3.1e-192 galE 5.1.3.2 M Belongs to the NAD(P)-dependent epimerase dehydratase family
HHOFPIHL_01922 5.1e-223 galK 2.7.1.6 F Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HHOFPIHL_01923 5.2e-254 gph G Transporter
HHOFPIHL_01924 2.4e-37
HHOFPIHL_01925 0.0 pgm 5.4.2.2, 5.4.2.8 G Phosphoglucomutase phosphomannomutase, alpha beta alpha domain
HHOFPIHL_01926 1.4e-197 galM 5.1.3.3 G Catalyzes the interconversion of alpha and beta anomers of maltose
HHOFPIHL_01927 2.2e-207 mmgC 1.3.8.1 I Acyl-CoA dehydrogenase, C-terminal domain
HHOFPIHL_01928 1.1e-144 etfB C Electron transfer flavoprotein domain
HHOFPIHL_01929 1.3e-176 etfA C Electron transfer flavoprotein FAD-binding domain
HHOFPIHL_01930 4.3e-186 1.1.1.1 C nadph quinone reductase
HHOFPIHL_01931 3.8e-54 K Transcriptional
HHOFPIHL_01932 3.4e-126 hchA 3.5.1.124 S DJ-1/PfpI family
HHOFPIHL_01933 0.0 oppD EP Psort location Cytoplasmic, score
HHOFPIHL_01934 6.3e-81 6.3.3.2 S ASCH
HHOFPIHL_01935 1.4e-246 EGP Major facilitator Superfamily
HHOFPIHL_01936 2.3e-23
HHOFPIHL_01937 1.9e-152 map 3.4.11.18 E Methionine Aminopeptidase
HHOFPIHL_01938 7.4e-140 menG 2.1.1.163, 2.1.1.201 H Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)
HHOFPIHL_01939 1.4e-158 hipB K Helix-turn-helix
HHOFPIHL_01940 1.3e-119 mpg 3.2.2.21 L Belongs to the DNA glycosylase MPG family
HHOFPIHL_01941 7.5e-70 yeaO S Protein of unknown function, DUF488
HHOFPIHL_01942 5.5e-124 pgmB 2.4.1.64, 3.1.3.12, 3.2.1.28, 5.4.2.6 GH37,GH65 S HAD-hyrolase-like
HHOFPIHL_01943 7.9e-79 usp1 T Universal stress protein family
HHOFPIHL_01944 6.2e-264 U Belongs to the BCCT transporter (TC 2.A.15) family
HHOFPIHL_01945 9.1e-115 maa 2.3.1.18, 2.3.1.79 S Maltose O-acetyltransferase
HHOFPIHL_01946 2.5e-83 S 3-demethylubiquinone-9 3-methyltransferase
HHOFPIHL_01947 2.9e-145 rnhA 3.1.26.4 L Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HHOFPIHL_01948 4.5e-85
HHOFPIHL_01949 6.4e-240 codA 3.5.4.1 F cytosine deaminase
HHOFPIHL_01950 1.4e-47
HHOFPIHL_01951 1.1e-152 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHOFPIHL_01952 5.2e-18
HHOFPIHL_01953 3.2e-124 yrkL S Flavodoxin-like fold
HHOFPIHL_01955 6.2e-30
HHOFPIHL_01957 1e-37 S Cytochrome B5
HHOFPIHL_01958 2.1e-31 cspC K Cold shock protein
HHOFPIHL_01959 1.6e-111 XK27_00220 S Dienelactone hydrolase family
HHOFPIHL_01960 4.4e-52
HHOFPIHL_01961 1.8e-220 mutY L A G-specific adenine glycosylase
HHOFPIHL_01962 4.7e-307 E Bacterial extracellular solute-binding proteins, family 5 Middle
HHOFPIHL_01963 0.0 pelX M domain, Protein
HHOFPIHL_01964 1.1e-52
HHOFPIHL_01965 4.7e-196 6.3.1.20 H Lipoate-protein ligase
HHOFPIHL_01966 9.7e-67 gcvH E glycine cleavage
HHOFPIHL_01967 5.1e-184 tas C Aldo/keto reductase family
HHOFPIHL_01968 2.1e-32
HHOFPIHL_01969 4.3e-34 EG EamA-like transporter family
HHOFPIHL_01970 4.6e-129 EG EamA-like transporter family
HHOFPIHL_01971 8.6e-114 metI P ABC transporter permease
HHOFPIHL_01972 9.9e-58 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOFPIHL_01973 1.5e-119 metN P Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HHOFPIHL_01974 2.2e-145 P Belongs to the nlpA lipoprotein family
HHOFPIHL_01975 1.8e-20 tag 3.2.2.20 L glycosylase
HHOFPIHL_01976 4.1e-52 tag 3.2.2.20 L glycosylase
HHOFPIHL_01977 4.5e-310 E ABC transporter, substratebinding protein
HHOFPIHL_01979 0.0 3.2.1.21 GH3 G hydrolase, family 3
HHOFPIHL_01980 4.5e-188 pva1 3.5.1.24 M Linear amide C-N hydrolases, choloylglycine hydrolase family
HHOFPIHL_01981 1.7e-276 sbcC L Putative exonuclease SbcCD, C subunit
HHOFPIHL_01982 8.5e-207 sbcD L SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity
HHOFPIHL_01983 4.2e-106 tag 3.2.2.20 L glycosylase
HHOFPIHL_01984 1.2e-147 S Zinc-dependent metalloprotease
HHOFPIHL_01985 1e-168 XK27_00880 3.5.1.28 M hydrolase, family 25
HHOFPIHL_01986 3.2e-206 G Glycosyl hydrolases family 8
HHOFPIHL_01987 8.6e-56 yphJ 4.1.1.44 S decarboxylase
HHOFPIHL_01988 5.1e-80 yphH S Cupin domain
HHOFPIHL_01989 2e-76 K helix_turn_helix, mercury resistance
HHOFPIHL_01990 2e-100 yobS K Bacterial regulatory proteins, tetR family
HHOFPIHL_01991 1.2e-09 K MarR family
HHOFPIHL_01992 7.1e-231
HHOFPIHL_01993 3.4e-160 dkgB S reductase
HHOFPIHL_01994 7e-204 EGP Major facilitator Superfamily
HHOFPIHL_01995 2.1e-195 EGP Major facilitator Superfamily
HHOFPIHL_01996 1.2e-129 C Oxidoreductase
HHOFPIHL_01997 3.8e-41 ccmL CQ Ethanolamine utilisation protein EutN/carboxysome
HHOFPIHL_01998 1.8e-58 K helix_turn_helix, arabinose operon control protein
HHOFPIHL_01999 7.5e-60 S Domain of unknown function (DUF4430)
HHOFPIHL_02000 5.9e-178 U FFAT motif binding
HHOFPIHL_02001 3.6e-114 S ECF-type riboflavin transporter, S component
HHOFPIHL_02002 3.6e-307 ykoD_2 S AAA domain, putative AbiEii toxin, Type IV TA system
HHOFPIHL_02003 8.8e-159 P ABC-type cobalt transport system permease component CbiQ and related transporters
HHOFPIHL_02004 1.1e-71
HHOFPIHL_02005 9.4e-98 ubiX 2.5.1.129 H Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN
HHOFPIHL_02006 1.9e-283 ubiD 4.1.1.98 H 3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HHOFPIHL_02007 3.5e-160 K LysR substrate binding domain
HHOFPIHL_02008 2.3e-69 def 3.5.1.31, 3.5.1.88 J Removes the formyl group from the N-terminal Met of newly synthesized proteins
HHOFPIHL_02009 0.0 epsA I PAP2 superfamily
HHOFPIHL_02010 3e-54 S Domain of unknown function (DU1801)
HHOFPIHL_02011 7.2e-110 aqpZ U Belongs to the MIP aquaporin (TC 1.A.8) family
HHOFPIHL_02012 6.8e-110 pcp 3.4.19.3 O Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HHOFPIHL_02013 1.4e-175 L Integrase core domain
HHOFPIHL_02014 0.0 lmrA 3.6.3.44 V ABC transporter
HHOFPIHL_02015 2e-97 rmaB K Transcriptional regulator, MarR family
HHOFPIHL_02016 3.4e-121 S membrane transporter protein
HHOFPIHL_02017 1.6e-112 3.1.3.48 T Tyrosine phosphatase family
HHOFPIHL_02018 2.4e-120
HHOFPIHL_02019 3.9e-125 skfE V ATPases associated with a variety of cellular activities
HHOFPIHL_02020 5.5e-62 yvoA_1 K Transcriptional regulator, GntR family
HHOFPIHL_02021 3.1e-173 3.5.2.6 V Beta-lactamase enzyme family
HHOFPIHL_02022 2.2e-87 btuE 1.11.1.9 O Belongs to the glutathione peroxidase family
HHOFPIHL_02023 3.6e-200 bcr1 EGP Major facilitator Superfamily
HHOFPIHL_02024 8.6e-145 S Sucrose-6F-phosphate phosphohydrolase
HHOFPIHL_02025 1.8e-155 map 3.4.11.18 E Methionine Aminopeptidase
HHOFPIHL_02026 2.2e-93
HHOFPIHL_02027 3.5e-129 ydfG S KR domain
HHOFPIHL_02028 1.5e-64 hxlR K HxlR-like helix-turn-helix
HHOFPIHL_02029 7.4e-60 asp2 S Asp23 family, cell envelope-related function
HHOFPIHL_02030 3.6e-70 asp S Asp23 family, cell envelope-related function
HHOFPIHL_02031 3.4e-25
HHOFPIHL_02032 2.4e-90
HHOFPIHL_02033 4.4e-18 S Transglycosylase associated protein
HHOFPIHL_02034 9.4e-156
HHOFPIHL_02035 5.9e-270 asnS 6.1.1.22 J Asparaginyl-tRNA synthetase
HHOFPIHL_02036 5.2e-183 chaT1 U Major Facilitator Superfamily
HHOFPIHL_02037 2.4e-93 laaE K Transcriptional regulator PadR-like family
HHOFPIHL_02038 5.2e-66 lysM M LysM domain
HHOFPIHL_02039 1.2e-134 XK27_07210 6.1.1.6 S B3 4 domain
HHOFPIHL_02040 7.8e-123 iprA K Cyclic nucleotide-monophosphate binding domain
HHOFPIHL_02041 1.8e-170 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HHOFPIHL_02042 2e-213 arcT 2.6.1.1 E Aminotransferase
HHOFPIHL_02043 3.8e-257 arcD E Arginine ornithine antiporter
HHOFPIHL_02044 3.3e-197 argF 2.1.3.3, 2.1.3.6, 2.7.2.2 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHOFPIHL_02045 7.7e-238 arcA 3.5.3.6 E Arginine
HHOFPIHL_02046 1.1e-281 S C4-dicarboxylate anaerobic carrier
HHOFPIHL_02047 4.2e-226 2.1.1.80, 2.7.13.3, 3.1.1.61 T histidine kinase DNA gyrase B
HHOFPIHL_02048 1.2e-149 KT YcbB domain
HHOFPIHL_02049 1.2e-280 arcD S C4-dicarboxylate anaerobic carrier
HHOFPIHL_02050 1.6e-260 ytjP 3.5.1.18 E Dipeptidase
HHOFPIHL_02052 1.2e-208 ykiI
HHOFPIHL_02053 4.5e-106 thiJ-2 3.5.1.124 S DJ-1/PfpI family
HHOFPIHL_02054 1.6e-161 3.1.3.48 T Tyrosine phosphatase family
HHOFPIHL_02055 3.6e-220 EGP Major facilitator Superfamily
HHOFPIHL_02056 1.2e-36 S Protein of unknown function (DUF3781)
HHOFPIHL_02057 7.5e-39
HHOFPIHL_02058 1e-84 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
HHOFPIHL_02059 8.1e-126 V McrBC 5-methylcytosine restriction system component
HHOFPIHL_02060 1.8e-97 mcrB V COG1401 GTPase subunit of restriction endonuclease
HHOFPIHL_02061 1.7e-12 V HNH endonuclease
HHOFPIHL_02062 2.8e-43 S AAA domain, putative AbiEii toxin, Type IV TA system
HHOFPIHL_02066 3.6e-71
HHOFPIHL_02067 2.2e-27
HHOFPIHL_02068 6e-28 S Mor transcription activator family
HHOFPIHL_02069 6.7e-84 L Phage integrase SAM-like domain
HHOFPIHL_02070 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02071 5e-70 L Phage integrase SAM-like domain
HHOFPIHL_02072 1.2e-66 3.1.3.16 S Protein of unknown function (DUF1643)
HHOFPIHL_02073 4.8e-93 L Phage integrase SAM-like domain
HHOFPIHL_02075 1.6e-78 KL Phage plasmid primase P4 family
HHOFPIHL_02079 4.6e-12 polA 2.7.7.7 L 3'-5' exonuclease
HHOFPIHL_02081 6.4e-17
HHOFPIHL_02082 9.8e-07
HHOFPIHL_02083 1.2e-24 E Acetyltransferase (GNAT) domain
HHOFPIHL_02084 1.9e-122 dltD M Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein)
HHOFPIHL_02085 3.8e-21 dltC 6.1.1.13 J Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOFPIHL_02086 1.2e-155 dltB M MBOAT, membrane-bound O-acyltransferase family
HHOFPIHL_02087 2.2e-146 dltA 6.1.1.13 H Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall
HHOFPIHL_02089 7.9e-96 T PhoQ Sensor
HHOFPIHL_02090 3.1e-74 K Transcriptional regulatory protein, C terminal
HHOFPIHL_02091 1e-157 ydgH S MMPL family
HHOFPIHL_02093 8.3e-35 K Bacterial regulatory proteins, tetR family
HHOFPIHL_02095 1.8e-54 K Acetyltransferase (GNAT) domain
HHOFPIHL_02096 1e-254 aha1 P E1-E2 ATPase
HHOFPIHL_02097 1.5e-219 L Transposase
HHOFPIHL_02098 2e-60 S Protein of unknown function (DUF1624)
HHOFPIHL_02099 5.6e-109 brpA K Cell envelope-like function transcriptional attenuator common domain protein
HHOFPIHL_02100 3.6e-191 glpQ 3.1.4.46 C phosphodiesterase
HHOFPIHL_02102 3.4e-28
HHOFPIHL_02103 3.8e-39 yafP 3.6.4.13 K Acetyltransferase (GNAT) domain
HHOFPIHL_02104 6.1e-131 gpmA 5.4.2.11 G Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HHOFPIHL_02105 9.8e-267 M domain protein
HHOFPIHL_02106 4e-169 K AI-2E family transporter
HHOFPIHL_02107 4.3e-214 xylR GK ROK family
HHOFPIHL_02108 1e-125
HHOFPIHL_02109 2e-238 cfa 2.1.1.317, 2.1.1.79 M cyclopropane-fatty-acyl-phospholipid synthase
HHOFPIHL_02110 4.3e-53 azlD S branched-chain amino acid
HHOFPIHL_02111 8.5e-137 azlC E AzlC protein
HHOFPIHL_02112 1.3e-87 ywnH 2.3.1.183 M Acetyltransferase (GNAT) domain
HHOFPIHL_02113 2.9e-254 gor 1.8.1.7 C Glutathione reductase
HHOFPIHL_02114 1.8e-37 S Domain of unknown function (DUF4430)
HHOFPIHL_02115 1.5e-195 L Transposase
HHOFPIHL_02116 6.5e-23 L Transposase
HHOFPIHL_02117 2.3e-161 V domain protein
HHOFPIHL_02118 4.4e-239 dacA 3.4.16.4 M Belongs to the peptidase S11 family
HHOFPIHL_02119 8.7e-215 hpk31 2.7.13.3 T Histidine kinase
HHOFPIHL_02120 3.5e-123 K response regulator
HHOFPIHL_02121 2.8e-210 guaB 1.1.1.205 F Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides
HHOFPIHL_02122 8.8e-107
HHOFPIHL_02123 3.1e-133 XK27_01040 S Protein of unknown function (DUF1129)
HHOFPIHL_02124 4.4e-200 ychF J ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner
HHOFPIHL_02125 8.5e-33 yyzM S Bacterial protein of unknown function (DUF951)
HHOFPIHL_02126 3.4e-155 spo0J K Belongs to the ParB family
HHOFPIHL_02127 4.1e-136 soj D Sporulation initiation inhibitor
HHOFPIHL_02128 5e-148 noc K Belongs to the ParB family
HHOFPIHL_02129 1.7e-131 rsmG 2.1.1.170 J Specifically methylates the N7 position of a guanine in 16S rRNA
HHOFPIHL_02130 1.3e-162 cpdA 2.1.2.2, 3.1.4.17, 3.1.4.53 S Calcineurin-like phosphoesterase
HHOFPIHL_02131 1.5e-169 rihC 3.2.2.1, 3.2.2.8 F Nucleoside
HHOFPIHL_02132 6.4e-214 pbuO_1 S Permease family
HHOFPIHL_02133 1.4e-226 nupG F Nucleoside
HHOFPIHL_02134 1.4e-153 5.4.2.7 G Metalloenzyme superfamily
HHOFPIHL_02135 1.6e-114 GM NmrA-like family
HHOFPIHL_02136 6.3e-44
HHOFPIHL_02137 1.1e-88
HHOFPIHL_02138 4.1e-40
HHOFPIHL_02139 1.1e-62 K HxlR-like helix-turn-helix
HHOFPIHL_02140 3.5e-34
HHOFPIHL_02141 1.2e-117
HHOFPIHL_02142 5.1e-310
HHOFPIHL_02143 1.8e-234 L Transposase
HHOFPIHL_02144 4e-94
HHOFPIHL_02145 2.2e-87
HHOFPIHL_02146 4.3e-80 EK Aminotransferase, class I
HHOFPIHL_02147 8.7e-123 EK Aminotransferase, class I
HHOFPIHL_02148 3.1e-167 K LysR substrate binding domain
HHOFPIHL_02149 6.2e-11 S Protein of unknown function (DUF2922)
HHOFPIHL_02150 3e-27
HHOFPIHL_02151 3.7e-99 K DNA-templated transcription, initiation
HHOFPIHL_02152 3.1e-206
HHOFPIHL_02153 1.5e-59
HHOFPIHL_02154 4.6e-54
HHOFPIHL_02155 7.7e-196 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HHOFPIHL_02156 8.5e-229 macB3 V ABC transporter, ATP-binding protein
HHOFPIHL_02157 6.8e-20 macB3 V ABC transporter, ATP-binding protein
HHOFPIHL_02158 2.1e-109 thiE 2.5.1.3 H Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
HHOFPIHL_02159 4.9e-148 thiD 2.5.1.3, 2.7.1.49, 2.7.4.7, 4.1.99.17 H Phosphomethylpyrimidine kinase
HHOFPIHL_02160 1.8e-139 thiM 2.7.1.50 H Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
HHOFPIHL_02161 2.7e-149 vdlC S Enoyl-(Acyl carrier protein) reductase
HHOFPIHL_02162 2.8e-129 ybbM S Uncharacterised protein family (UPF0014)
HHOFPIHL_02163 4.2e-118 ybbL S ABC transporter, ATP-binding protein
HHOFPIHL_02164 2.5e-275 rumA 2.1.1.190, 2.1.1.35 J Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HHOFPIHL_02165 2.6e-91
HHOFPIHL_02166 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02170 1e-28
HHOFPIHL_02172 6.8e-15 K Helix-turn-helix XRE-family like proteins
HHOFPIHL_02173 2.7e-81 P CorA-like Mg2+ transporter protein
HHOFPIHL_02174 2.7e-70 XK27_00890 S Domain of unknown function (DUF368)
HHOFPIHL_02175 1.2e-50 XK27_00890 S Domain of unknown function (DUF368)
HHOFPIHL_02176 2.8e-134 K helix_turn_helix, mercury resistance
HHOFPIHL_02177 1.8e-223 xylR GK ROK family
HHOFPIHL_02178 2.9e-159 akr5f 1.1.1.346 C Aldo keto reductase
HHOFPIHL_02179 5.2e-248 rarA L recombination factor protein RarA
HHOFPIHL_02180 3.4e-278 rny S Endoribonuclease that initiates mRNA decay
HHOFPIHL_02181 1.9e-124 yoaK S Protein of unknown function (DUF1275)
HHOFPIHL_02182 3.5e-174 D Alpha beta
HHOFPIHL_02183 0.0 pepF2 E Oligopeptidase F
HHOFPIHL_02184 5.4e-74 K Transcriptional regulator
HHOFPIHL_02185 3e-164
HHOFPIHL_02186 3.3e-192 S DUF218 domain
HHOFPIHL_02187 1.5e-253 brnQ U Component of the transport system for branched-chain amino acids
HHOFPIHL_02188 3.7e-157 nanK 2.7.1.2 GK ROK family
HHOFPIHL_02189 6.1e-252 frlA E Amino acid permease
HHOFPIHL_02190 3.6e-252 brnQ U Component of the transport system for branched-chain amino acids
HHOFPIHL_02191 1.2e-34 S SEC-C Motif Domain Protein
HHOFPIHL_02192 1.4e-194 S DNA/RNA non-specific endonuclease
HHOFPIHL_02194 2.2e-51
HHOFPIHL_02195 8.7e-78 K Winged helix DNA-binding domain
HHOFPIHL_02196 1.3e-111 nnrD 4.2.1.136, 5.1.99.6 H Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX
HHOFPIHL_02197 5.7e-103 ddpX 3.4.13.22 E Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HHOFPIHL_02198 7.1e-77
HHOFPIHL_02199 1.3e-27
HHOFPIHL_02200 4.2e-191 pva3 3.5.1.24 M Linear amide C-N hydrolase, choloylglycine hydrolase family protein
HHOFPIHL_02201 3.8e-84 iap CBM50 M NlpC P60 family
HHOFPIHL_02202 8.4e-293 ytgP S Polysaccharide biosynthesis protein
HHOFPIHL_02203 1.1e-59 K Helix-turn-helix domain
HHOFPIHL_02204 0.0 yuxL 3.4.19.1 E Prolyl oligopeptidase family
HHOFPIHL_02205 3.1e-170 panE2 1.1.1.169 H Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HHOFPIHL_02206 8.8e-44
HHOFPIHL_02207 5.7e-65 spxA 1.20.4.1 K Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress
HHOFPIHL_02208 0.0 yjcE P Sodium proton antiporter
HHOFPIHL_02209 4.4e-311 cpdB 3.1.3.6, 3.1.4.16 F Belongs to the 5'-nucleotidase family
HHOFPIHL_02210 6.3e-307 astA 2.8.2.22 M Arylsulfotransferase Ig-like domain
HHOFPIHL_02211 3.2e-116 yoaK S Protein of unknown function (DUF1275)
HHOFPIHL_02212 8.1e-155 rihA F Inosine-uridine preferring nucleoside hydrolase
HHOFPIHL_02214 4.1e-188 nupC F Na+ dependent nucleoside transporter C-terminus
HHOFPIHL_02215 9.8e-150 1.1.1.1 C alcohol dehydrogenase
HHOFPIHL_02216 3.3e-75 S Membrane
HHOFPIHL_02217 8.2e-112 trpF 5.3.1.24 E belongs to the TrpF family
HHOFPIHL_02218 1.1e-122 yeiI 2.7.1.15, 2.7.1.45, 2.7.1.83 G Phosphomethylpyrimidine kinase
HHOFPIHL_02219 5.4e-110 psuK 2.7.1.15, 2.7.1.45, 2.7.1.83 GK Winged helix-turn-helix DNA-binding
HHOFPIHL_02221 1.9e-178 K helix_turn _helix lactose operon repressor
HHOFPIHL_02222 6.1e-29 mcbG S Pentapeptide repeats (8 copies)
HHOFPIHL_02223 1e-99 ywlG S Belongs to the UPF0340 family
HHOFPIHL_02224 4e-84 hmpT S ECF-type riboflavin transporter, S component
HHOFPIHL_02225 7.4e-141 thiD 2.7.1.35, 2.7.1.49, 2.7.4.7 H Phosphomethylpyrimidine kinase
HHOFPIHL_02226 1.1e-261 norG_2 K Aminotransferase class I and II
HHOFPIHL_02227 3.9e-223 lytR5 K Cell envelope-related transcriptional attenuator domain
HHOFPIHL_02228 1e-139 P ATPases associated with a variety of cellular activities
HHOFPIHL_02229 1.9e-144 opuAB P Binding-protein-dependent transport system inner membrane component
HHOFPIHL_02230 1e-159 opuAB P Binding-protein-dependent transport system inner membrane component
HHOFPIHL_02231 9.3e-228 rodA D Cell cycle protein
HHOFPIHL_02232 4.3e-95
HHOFPIHL_02234 6.8e-71 4.4.1.5 E Glyoxalase
HHOFPIHL_02235 4.7e-140 S Membrane
HHOFPIHL_02236 2.8e-185 tdh 1.1.1.14 C Zinc-binding dehydrogenase
HHOFPIHL_02237 1.8e-172 scrK 2.7.1.2, 2.7.1.4 GK ROK family
HHOFPIHL_02238 4.4e-76
HHOFPIHL_02239 2.7e-205 gldA 1.1.1.6 C dehydrogenase
HHOFPIHL_02240 5.7e-55 ykkC P Small Multidrug Resistance protein
HHOFPIHL_02241 9.7e-52 sugE P Multidrug resistance protein
HHOFPIHL_02242 1.8e-106 speG J Acetyltransferase (GNAT) domain
HHOFPIHL_02243 3.6e-146 G Belongs to the phosphoglycerate mutase family
HHOFPIHL_02245 0.0 treP 2.4.1.64 GH65 G hydrolase, family 65, central catalytic
HHOFPIHL_02246 1.6e-199 nlhH_1 I alpha/beta hydrolase fold
HHOFPIHL_02247 9.5e-253 xylP2 G symporter
HHOFPIHL_02248 2.3e-309 E ABC transporter, substratebinding protein
HHOFPIHL_02249 6.8e-84
HHOFPIHL_02250 2.3e-07
HHOFPIHL_02251 9.5e-178 K Transcriptional regulator, LacI family
HHOFPIHL_02252 1.3e-96 G Major Facilitator
HHOFPIHL_02253 3.1e-156 G Major Facilitator
HHOFPIHL_02254 0.0 3.2.1.10, 3.2.1.20 GH13,GH31 G Alpha amylase, catalytic domain protein
HHOFPIHL_02255 3.6e-117
HHOFPIHL_02256 6.4e-75 K helix_turn_helix, mercury resistance
HHOFPIHL_02257 1.2e-224 C Oxidoreductase
HHOFPIHL_02258 3.1e-12
HHOFPIHL_02259 1.2e-67 K Transcriptional regulator, HxlR family
HHOFPIHL_02260 2.6e-213 mccF V LD-carboxypeptidase
HHOFPIHL_02261 2.8e-179 rihB 3.2.2.1, 3.2.2.8 F Nucleoside
HHOFPIHL_02262 8.9e-119 yeiL K Cyclic nucleotide-monophosphate binding domain
HHOFPIHL_02263 7.6e-172 P Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HHOFPIHL_02264 3.4e-219 dhaT 1.1.1.1, 1.1.1.202 C Dehydrogenase
HHOFPIHL_02265 6.1e-125 hadL 3.8.1.2 S Haloacid dehalogenase-like hydrolase
HHOFPIHL_02266 3e-121 S GyrI-like small molecule binding domain
HHOFPIHL_02267 3.7e-69 ycgX S Protein of unknown function (DUF1398)
HHOFPIHL_02268 2.1e-99 S Phosphatidylethanolamine-binding protein
HHOFPIHL_02269 9.2e-224 EGP Major facilitator Superfamily
HHOFPIHL_02270 1.7e-122 devA 3.6.3.25 V ABC transporter, ATP-binding protein
HHOFPIHL_02271 3.4e-181 hrtB V ABC transporter permease
HHOFPIHL_02272 2.4e-87 ygfC K Bacterial regulatory proteins, tetR family
HHOFPIHL_02273 2.9e-205 ynfM EGP Major facilitator Superfamily
HHOFPIHL_02274 1.4e-84 thiW S Thiamine-precursor transporter protein (ThiW)
HHOFPIHL_02275 1.5e-167 mleP S Sodium Bile acid symporter family
HHOFPIHL_02276 1e-309 sfcA 1.1.1.38, 4.1.1.101 C Malic enzyme
HHOFPIHL_02277 4.2e-161 mleR K LysR family
HHOFPIHL_02278 3.7e-148 K Helix-turn-helix domain, rpiR family
HHOFPIHL_02279 1.8e-217 aguA 3.5.3.12 E agmatine deiminase
HHOFPIHL_02280 4.5e-169 arcC 2.7.2.2 E Belongs to the carbamate kinase family
HHOFPIHL_02281 1e-217 aguA 3.5.3.12 E agmatine deiminase
HHOFPIHL_02282 2e-234 aguD E Amino Acid
HHOFPIHL_02283 6.6e-198 ptcA 2.1.3.3, 2.1.3.6 E Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HHOFPIHL_02284 8.1e-239 nhaC C Na H antiporter NhaC
HHOFPIHL_02285 6.8e-262 E Amino acid permease
HHOFPIHL_02286 0.0 tdc 4.1.1.25 E Pyridoxal-dependent decarboxylase conserved domain
HHOFPIHL_02287 2.2e-240 tyrS 6.1.1.1 J Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HHOFPIHL_02288 1.3e-38
HHOFPIHL_02291 2.7e-208 atoB 1.1.1.88, 2.3.1.9 I Belongs to the thiolase family
HHOFPIHL_02292 1.9e-26
HHOFPIHL_02293 6.3e-157 EG EamA-like transporter family
HHOFPIHL_02294 4.4e-304 abfA 3.2.1.55 GH51 G Alpha-L-arabinofuranosidase C-terminus
HHOFPIHL_02295 3.6e-39
HHOFPIHL_02296 6.4e-14 S Transglycosylase associated protein
HHOFPIHL_02297 7.8e-14 yjdF S Protein of unknown function (DUF2992)
HHOFPIHL_02298 1.2e-157 K Transcriptional regulator
HHOFPIHL_02299 3.7e-306 3.2.1.45 GH30 G Glycosyl hydrolase family 30 TIM-barrel domain
HHOFPIHL_02300 3.2e-138 S Belongs to the UPF0246 family
HHOFPIHL_02301 8.4e-111 pyrE 2.4.2.10, 4.1.1.23 F Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HHOFPIHL_02302 5.3e-122 pyrF 4.1.1.23 F Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP)
HHOFPIHL_02303 7.5e-217 naiP EGP Major facilitator Superfamily
HHOFPIHL_02304 1.2e-134 S Protein of unknown function
HHOFPIHL_02305 5e-170 pepI 3.4.11.5, 3.5.1.101 E Releases the N-terminal proline from various substrates
HHOFPIHL_02306 5.5e-161 G Belongs to the carbohydrate kinase PfkB family
HHOFPIHL_02307 2.9e-254 F Belongs to the purine-cytosine permease (2.A.39) family
HHOFPIHL_02308 1.7e-187 yegU O ADP-ribosylglycohydrolase
HHOFPIHL_02309 2.3e-122 yihL K UTRA
HHOFPIHL_02310 1.5e-166 yhaZ L DNA alkylation repair enzyme
HHOFPIHL_02311 4.5e-131 yfeJ 6.3.5.2 F glutamine amidotransferase
HHOFPIHL_02312 0.0 tetP J elongation factor G
HHOFPIHL_02313 3.9e-234 EK Aminotransferase, class I
HHOFPIHL_02314 9.7e-138 IQ reductase
HHOFPIHL_02315 6.8e-98 K Bacterial regulatory proteins, tetR family
HHOFPIHL_02316 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02317 4.5e-73 S COG NOG18757 non supervised orthologous group
HHOFPIHL_02318 4.2e-209 pmrB EGP Major facilitator Superfamily
HHOFPIHL_02319 1.9e-115 lacA 2.3.1.18, 2.3.1.79 S Maltose acetyltransferase
HHOFPIHL_02320 7.2e-81
HHOFPIHL_02321 1.5e-25
HHOFPIHL_02322 4.9e-119 cah 4.2.1.1 P Eukaryotic-type carbonic anhydrase
HHOFPIHL_02323 1e-173 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_02324 1.5e-141 U Binding-protein-dependent transport system inner membrane component
HHOFPIHL_02325 2.6e-152 U Binding-protein-dependent transport system inner membrane component
HHOFPIHL_02326 1.6e-249 G Bacterial extracellular solute-binding protein
HHOFPIHL_02327 1.9e-214 P Belongs to the ABC transporter superfamily
HHOFPIHL_02328 3.4e-172 lacM 3.2.1.23, 3.2.1.35, 3.2.1.51, 3.2.1.97 GH101,GH29 G beta-galactosidase
HHOFPIHL_02329 0.0 lacL 3.2.1.23 G Belongs to the glycosyl hydrolase 2 family
HHOFPIHL_02330 9.8e-71 K Transcriptional regulator
HHOFPIHL_02331 1.9e-94 qorB 1.6.5.2 GM NmrA-like family
HHOFPIHL_02332 1.7e-211 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHOFPIHL_02333 5.8e-76 M Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
HHOFPIHL_02335 1.1e-141 K Helix-turn-helix domain
HHOFPIHL_02336 4.7e-168
HHOFPIHL_02337 0.0 addA 3.6.4.12 L ATP-dependent helicase nuclease subunit A
HHOFPIHL_02338 0.0 rexB 3.1.21.3, 3.6.4.12 L The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. This subunit has 5' - 3' nuclease activity
HHOFPIHL_02339 9.1e-217 argE 3.5.1.18 E succinyl-diaminopimelate desuccinylase
HHOFPIHL_02340 6.2e-185 xynD 3.5.1.104 G polysaccharide deacetylase
HHOFPIHL_02341 1.3e-58
HHOFPIHL_02342 4.6e-103 GM NAD(P)H-binding
HHOFPIHL_02343 5.7e-183 iolS C Aldo keto reductase
HHOFPIHL_02344 5.9e-228 pbuG S permease
HHOFPIHL_02345 1.7e-93 K helix_turn_helix multiple antibiotic resistance protein
HHOFPIHL_02346 2.7e-166 drrA V ABC transporter
HHOFPIHL_02347 7e-120 drrB U ABC-2 type transporter
HHOFPIHL_02348 1.5e-169 2.5.1.74 H UbiA prenyltransferase family
HHOFPIHL_02349 0.0 S Bacterial membrane protein YfhO
HHOFPIHL_02350 1.2e-86 ccl S QueT transporter
HHOFPIHL_02352 1.4e-175 L Integrase core domain
HHOFPIHL_02353 2.2e-32
HHOFPIHL_02354 0.0 S Predicted membrane protein (DUF2207)
HHOFPIHL_02355 0.0 xynB 3.2.1.37 GH43 G Belongs to the glycosyl hydrolase 43 family
HHOFPIHL_02356 2.7e-282 xynT G MFS/sugar transport protein
HHOFPIHL_02357 6.2e-152 rhaS2 K Transcriptional regulator, AraC family
HHOFPIHL_02358 2.8e-279 cls I Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HHOFPIHL_02359 5.2e-22
HHOFPIHL_02360 4.1e-150 F DNA/RNA non-specific endonuclease
HHOFPIHL_02361 4.5e-89
HHOFPIHL_02364 1.2e-51
HHOFPIHL_02365 3.1e-113 L haloacid dehalogenase-like hydrolase
HHOFPIHL_02366 1.7e-254 pepC 3.4.22.40 E aminopeptidase
HHOFPIHL_02367 1.6e-79 K helix_turn_helix multiple antibiotic resistance protein
HHOFPIHL_02368 4.2e-109 lepB 3.4.21.89 U Belongs to the peptidase S26 family
HHOFPIHL_02369 1.5e-206 tcaB EGP Major facilitator Superfamily
HHOFPIHL_02370 1.6e-227 S module of peptide synthetase
HHOFPIHL_02371 1.2e-91 ykhA 3.1.2.20 I Thioesterase superfamily
HHOFPIHL_02372 1.4e-98 J Acetyltransferase (GNAT) domain
HHOFPIHL_02373 5.1e-116 ywnB S NAD(P)H-binding
HHOFPIHL_02374 5.5e-245 brnQ U Component of the transport system for branched-chain amino acids
HHOFPIHL_02375 4.3e-37
HHOFPIHL_02376 2.6e-126 yjjG 3.1.3.102, 3.1.3.104, 3.1.3.5, 3.8.1.2 S HAD-hyrolase-like
HHOFPIHL_02377 1e-37
HHOFPIHL_02378 5.5e-48
HHOFPIHL_02379 7.2e-225 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHOFPIHL_02380 2.4e-124 gidA D NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
HHOFPIHL_02381 3.2e-256 mnmE S Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HHOFPIHL_02382 5.9e-111 jag S R3H domain protein
HHOFPIHL_02383 1e-145 yidC U Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HHOFPIHL_02384 3.2e-59 rnpA 3.1.26.5 J RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
HHOFPIHL_02385 2.6e-14 rpmH J Belongs to the bacterial ribosomal protein bL34 family
HHOFPIHL_02386 1.1e-54 L recombinase activity
HHOFPIHL_02391 1.8e-31 L Transposase DDE domain
HHOFPIHL_02392 1.6e-46 S Protein of unknown function (DUF2992)
HHOFPIHL_02393 3.3e-20 L Transposase
HHOFPIHL_02394 2.6e-50 L Transposase
HHOFPIHL_02395 2.2e-74 S Protein of unknown function with HXXEE motif
HHOFPIHL_02396 1e-117 L Integrase core domain
HHOFPIHL_02397 2.9e-70 hsdS 3.1.21.3 V Type I restriction modification DNA specificity domain
HHOFPIHL_02398 1.7e-217 hsdM 2.1.1.72 V type I restriction-modification system
HHOFPIHL_02399 2.2e-294 hsdR 3.1.21.3 L Type I restriction enzyme R protein N terminus (HSDR_N)
HHOFPIHL_02400 1.3e-112 S Fic/DOC family
HHOFPIHL_02402 4.7e-07 K Helix-turn-helix domain
HHOFPIHL_02403 5.5e-127 U TraM recognition site of TraD and TraG
HHOFPIHL_02404 9.4e-25 I mechanosensitive ion channel activity
HHOFPIHL_02406 3.7e-21
HHOFPIHL_02407 6.7e-127 U type IV secretory pathway VirB4
HHOFPIHL_02408 3.6e-28 M CHAP domain
HHOFPIHL_02412 1.3e-41 soj D Sporulation initiation inhibitor
HHOFPIHL_02413 4.4e-110 K Primase C terminal 1 (PriCT-1)
HHOFPIHL_02414 1.2e-36 S Protein of unknown function (DUF3102)
HHOFPIHL_02417 3.1e-08 CO Thioredoxin
HHOFPIHL_02422 1.8e-26 ruvB 3.6.4.12 L four-way junction helicase activity
HHOFPIHL_02424 2.7e-23 L Protein of unknown function (DUF3991)
HHOFPIHL_02425 3e-184 uvrX 2.7.7.7 L Belongs to the DNA polymerase type-Y family
HHOFPIHL_02427 5.9e-22
HHOFPIHL_02428 2e-17 N PFAM YcfA family protein
HHOFPIHL_02429 8.6e-43 S PFAM Uncharacterised protein family UPF0150
HHOFPIHL_02430 4.8e-22 L Psort location Cytoplasmic, score
HHOFPIHL_02431 2.6e-92 topB 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HHOFPIHL_02433 4.1e-139 clpB O Belongs to the ClpA ClpB family
HHOFPIHL_02438 4.6e-29 3.4.22.70 M by MetaGeneAnnotator
HHOFPIHL_02440 1.4e-17 M domain protein
HHOFPIHL_02442 6e-104
HHOFPIHL_02443 3.2e-09 2.1.1.72, 3.1.21.3 AA10,CBM73 L Belongs to the N(4) N(6)-methyltransferase family
HHOFPIHL_02445 5.3e-27 C Lantibiotic biosynthesis dehydratase C-term
HHOFPIHL_02446 3.7e-86 V ABC transporter transmembrane region
HHOFPIHL_02447 7.1e-82 V ABC transporter transmembrane region
HHOFPIHL_02448 2.4e-22 2.7.7.73, 2.7.7.80 H Involved in molybdopterin and thiamine biosynthesis, family 2
HHOFPIHL_02450 1.5e-67 L the current gene model (or a revised gene model) may contain a frame shift
HHOFPIHL_02451 2e-52
HHOFPIHL_02452 9.3e-208 npr 1.11.1.1 C Pyridine nucleotide-disulphide oxidoreductase
HHOFPIHL_02453 6.9e-231 1.7.1.15 S Pyridine nucleotide-disulphide oxidoreductase
HHOFPIHL_02454 8e-100 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HHOFPIHL_02455 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02458 2.1e-47 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HHOFPIHL_02460 8.3e-176 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02461 1e-32 L Integrase
HHOFPIHL_02462 1.3e-294 cadA P P-type ATPase
HHOFPIHL_02463 1.7e-162 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_02464 3.3e-92 K Transcriptional regulatory protein, C terminal
HHOFPIHL_02465 7.7e-146 T HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain
HHOFPIHL_02466 1.4e-84 dedA S SNARE associated Golgi protein
HHOFPIHL_02467 3.5e-51 lssY 3.6.1.27 I PAP2 superfamily
HHOFPIHL_02468 2.2e-131 ykoT GT2 M Glycosyl transferase family 2
HHOFPIHL_02469 1.6e-189 M 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HHOFPIHL_02472 9e-60
HHOFPIHL_02473 6.9e-30 S FMN_bind
HHOFPIHL_02474 2.9e-54 apbE 2.7.1.180 H Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein
HHOFPIHL_02475 6.3e-126 P FAD-binding domain
HHOFPIHL_02476 4.7e-51 tnp2PF3 L Putative transposase of IS4/5 family (DUF4096)
HHOFPIHL_02477 3.1e-56 tnp2PF3 L Transposase DDE domain
HHOFPIHL_02478 1.8e-23 K sequence-specific DNA binding
HHOFPIHL_02479 1.1e-54 S Bacterial mobilisation protein (MobC)
HHOFPIHL_02480 3.2e-185 U Relaxase/Mobilisation nuclease domain
HHOFPIHL_02481 1.1e-78 repA S Replication initiator protein A
HHOFPIHL_02482 1.6e-35 ligA 6.5.1.2 L DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HHOFPIHL_02483 1.6e-143 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HHOFPIHL_02484 1.2e-23 S Family of unknown function (DUF5388)
HHOFPIHL_02485 3.7e-62 L Integrase core domain
HHOFPIHL_02486 3.7e-57 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02488 4.7e-25
HHOFPIHL_02489 0.0 mco Q Multicopper oxidase
HHOFPIHL_02490 4.6e-239 EGP Major Facilitator Superfamily
HHOFPIHL_02491 2.9e-76 ybgJ 3.5.1.54 E Allophanate hydrolase subunit 1
HHOFPIHL_02492 3e-91 kipA 6.3.4.6 E Allophanate hydrolase subunit 2
HHOFPIHL_02493 3.1e-37 accB 2.3.1.12, 4.1.1.3 I first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
HHOFPIHL_02494 9.6e-218 accC 6.3.4.14, 6.4.1.2 I Acetyl-CoA carboxylase biotin carboxylase subunit
HHOFPIHL_02495 3.8e-129 ycsI S Protein of unknown function (DUF1445)
HHOFPIHL_02496 3.4e-111 ycsF S LamB/YcsF family
HHOFPIHL_02497 1.4e-183 ycsG P Natural resistance-associated macrophage protein
HHOFPIHL_02498 1.1e-63 L Transposase
HHOFPIHL_02499 3.5e-131 tnp L DDE domain
HHOFPIHL_02500 2.4e-147 D CobQ CobB MinD ParA nucleotide binding domain protein
HHOFPIHL_02502 2.9e-58
HHOFPIHL_02503 2.8e-28
HHOFPIHL_02504 5.9e-68 S protein conserved in bacteria
HHOFPIHL_02505 1.6e-42
HHOFPIHL_02506 1.2e-26
HHOFPIHL_02507 5.2e-111 L MobA MobL family protein
HHOFPIHL_02508 2.7e-247 traA L MobA/MobL family
HHOFPIHL_02509 6.9e-221 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HHOFPIHL_02510 1.6e-93 S Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
HHOFPIHL_02511 2.8e-193 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02512 1.9e-82 bioY S BioY family
HHOFPIHL_02513 4.1e-189 birA 6.3.4.15 H Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor
HHOFPIHL_02514 1.3e-173 L Transposase and inactivated derivatives, IS30 family
HHOFPIHL_02515 1e-140 cylB V ABC-2 type transporter
HHOFPIHL_02516 1.9e-30 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HHOFPIHL_02517 2.7e-174 L Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair
HHOFPIHL_02518 1.6e-109 cylA V AAA domain, putative AbiEii toxin, Type IV TA system
HHOFPIHL_02519 2.6e-103 L Helix-turn-helix domain of Hin and related proteins, a family of DNA-binding domains unique to bacteria and represented by the Hin protein of Salmonella. The basic HTH domain is a simple fold comprised of three core helices that form a right-handed
HHOFPIHL_02520 0.0 asnB 6.3.5.4 E Aluminium induced protein
HHOFPIHL_02521 7.2e-220 tnp L MULE transposase domain
HHOFPIHL_02522 4.1e-233 tagE 2.4.1.52 GT4 M Glycosyl transferases group 1
HHOFPIHL_02523 5.7e-94 L 4.5 Transposon and IS
HHOFPIHL_02524 3.9e-10 L Transposase
HHOFPIHL_02525 5.1e-196 L Psort location Cytoplasmic, score
HHOFPIHL_02526 2.9e-31
HHOFPIHL_02527 0.0 traI 5.99.1.2 L This gene contains a nucleotide ambiguity which may be the result of a sequencing error
HHOFPIHL_02528 6.2e-67
HHOFPIHL_02529 6.2e-117
HHOFPIHL_02530 0.0 L MobA MobL family protein
HHOFPIHL_02531 1.6e-26
HHOFPIHL_02532 1.2e-40
HHOFPIHL_02533 1.8e-84
HHOFPIHL_02534 3.9e-44 relB L Addiction module antitoxin, RelB DinJ family
HHOFPIHL_02535 1.2e-56 repA S Replication initiator protein A
HHOFPIHL_02536 7.6e-38 K Peptidase S24-like
HHOFPIHL_02537 1.4e-13 S Protein of unknown function (DUF805)
HHOFPIHL_02539 5.4e-47
HHOFPIHL_02542 1.2e-82
HHOFPIHL_02543 1.3e-60 L Transposase IS200 like
HHOFPIHL_02544 4e-172 L transposase, IS605 OrfB family
HHOFPIHL_02546 3.8e-98 soj D CobQ CobB MinD ParA nucleotide binding domain protein
HHOFPIHL_02547 2.1e-11
HHOFPIHL_02548 5.3e-175 L Integrase core domain
HHOFPIHL_02550 1.2e-12 ytgB S Transglycosylase associated protein
HHOFPIHL_02551 1.4e-130 S Phage Mu protein F like protein
HHOFPIHL_02552 3e-106 icaB G Polysaccharide deacetylase
HHOFPIHL_02554 1.5e-156 icaA GT2 M Glycosyl transferase
HHOFPIHL_02555 6.6e-155 2.7.7.7, 3.4.21.110 D Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HHOFPIHL_02556 1.9e-175 L Initiator Replication protein
HHOFPIHL_02557 3.9e-27
HHOFPIHL_02558 6.8e-107 L Integrase
HHOFPIHL_02559 1.7e-44 yefM 2.3.1.15 D Antitoxin component of a toxin-antitoxin (TA) module
HHOFPIHL_02560 2.4e-59 yafQ S endonuclease activity
HHOFPIHL_02561 1.4e-74 arsC 1.20.4.1 T Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HHOFPIHL_02562 1.1e-56 arsD S Arsenical resistance operon trans-acting repressor ArsD
HHOFPIHL_02563 1.8e-232 arsB U Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HHOFPIHL_02564 0.0 arsA 3.6.3.16 D Anion-transporting ATPase
HHOFPIHL_02565 2.7e-57 arsR K Helix-turn-helix domain
HHOFPIHL_02566 9.5e-61 L Domain of unknown function (DUF4158)
HHOFPIHL_02567 1.7e-84 dps P Belongs to the Dps family
HHOFPIHL_02568 8.8e-88 S Protein of unknown function, DUF536
HHOFPIHL_02569 4e-37 S Bacteriophage abortive infection AbiH
HHOFPIHL_02570 5.8e-127 3.1.21.3 V Type I restriction modification DNA specificity domain
HHOFPIHL_02571 1.4e-73
HHOFPIHL_02572 2.7e-179 L Lactococcus lactis RepB C-terminus
HHOFPIHL_02573 1.5e-219 L Transposase
HHOFPIHL_02574 2.3e-107 L Integrase
HHOFPIHL_02575 4.8e-44 T Antidote-toxin recognition MazE, bacterial antitoxin
HHOFPIHL_02576 4.9e-57 pemK T PemK-like, MazF-like toxin of type II toxin-antitoxin system
HHOFPIHL_02577 3.5e-07 L Initiator Replication protein
HHOFPIHL_02578 6.1e-112
HHOFPIHL_02579 3.4e-100 D Relaxase/Mobilisation nuclease domain
HHOFPIHL_02580 1.5e-13 mobC S Bacterial mobilisation protein (MobC)

eggNOG-mapper v2 (Database: eggNOG v5.0, Jul. 2018 release)